-- dump date 20111121_010300 -- class Genbank::CDS -- table cds_note -- id note YP_002563157.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.501(Affirmative) YP_002563158.1 psort: bacterial inner membrane --- Certainty= 0.198(Affirmative); COG0026 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) YP_002563159.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative) YP_002563160.1 psort: bacterial inner membrane --- Certainty= 0.429(Affirmative); COG0772 FtsW bacterial cell division membrane protein YP_002563161.1 psort: bacterial inner membrane --- Certainty= 0.117(Affirmative) YP_002563162.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.277(Affirmative); COG0789 SoxR Predicted transcriptional regulators YP_002563163.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.158(Affirmative) YP_002563164.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.297(Affirmative) YP_002563165.1 psort: bacterial inner membrane --- Certainty= 0.164(Affirmative); COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes YP_002563166.1 psort: bacterial inner membrane --- Certainty= 0.136(Affirmative); COG0180 trpS tryptophanyl-tRNA synthetase YP_002563167.1 posrt: bacterial cytoplasm --- Certainty= 0.292(Affirmative); COG0576 GrpE molecular chaperone GrpE (heat shock protein) YP_002563168.1 posrt: bacterial inner membrane --- Certainty= 0.109(Affirmative); COG0117 RibD pyrimidine deaminase YP_002563169.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002563170.1 psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG1314 SecG Preprotein translocase subunit YP_002563171.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.270(Affirmative) YP_002563172.1 psort: bacterial inner membrane --- Certainty= 0.285(Affirmative); COG0582 XerC integrase YP_002563173.1 psort: bacterial cytoplasm --- Certainty= 0.231(Affirmative); COG1136 PhnL ABC-type transport systems, involved in lipoprotein release, ATPase components YP_002563174.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002563175.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.234(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.646 Max cleavage site probability: 0.575 between pos. 27 and 28 YP_002563176.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_002563177.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.482(Affirmative) YP_002563178.1 member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 0.998 Max cleavage site probability: 0.848 between pos. 28 and 29 YP_002563179.1 member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.676(Affirmative) psort: bacterial periplasmic space --- Certainty= 0.193(Affirmative) YP_002563180.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.127(Affirmative) YP_002563181.1 Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.230(Affirmative); COG2104 ThiS Sulfur transfer protein involved in thiamine biosynthesis YP_002563182.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002563183.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.321(Affirmative) YP_002563184.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002563185.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.928(Affirmative) YP_002563186.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0742 N6-adenine-specific methylase YP_002563187.1 member of the MSP2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.973 between pos. 28 and 29 YP_002563188.1 psort: bacterial inner membrane --- Certainty= 0.440(Affirmative); COG0477 ProP permeases of the major facilitator superfamily YP_002563189.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002563190.1 posrt: bacterial inner membrane --- Certainty= 0.042(Affirmative); COG1207 GlmU N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) YP_002563191.1 psort: bacterial cytoplasm --- Certainty= 0.076(Affirmative); COG1028 FabG Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_002563192.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002563193.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002563194.1 psort: bacterial cytoplasm --- Certainty= 0.243(Affirmative); COG0291 RpmI ribosomal protein L35 YP_002563195.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.087(Affirmative) YP_002563196.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002563197.1 member of the msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.676(Affirmative) YP_002563198.1 member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.666 between pos. 28 and 29 YP_002563199.1 psort: bacterial inner membrane --- Certainty= 0.459(Affirmative) YP_002563200.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.072(Affirmative); COG2835 Uncharacterized BCR YP_002563201.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.530(Affirmative) bacterial periplasmic space --- Certainty= 0.164(Affirmative) YP_002563202.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.033(Affirmative) YP_002563203.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.440(Affirmative); COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains YP_002563204.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.013(Affirmative) YP_002563205.1 called by Glimmer 2; hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.581(Affirmative); COG1463 Permease component of an ABC-transporter YP_002563206.1 member of the msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.153(Affirmative) YP_002563207.1 member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.658 between pos. 28 and 29 YP_002563208.1 member of the msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.973 between pos. 28 and 29 YP_002563209.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002563210.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002563211.1 psort: bacterial outside --- Certainty= 0.300(Affirmative); COG0476 ThiF dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 YP_002563212.1 member of msp2 superfamily; psort: bacterial cytoplasm --- Certainty= 0.211(Affirmative) signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.933 between pos. 29 and 30 YP_002563213.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.126(Affirmative); COG0679 Predicted permeases YP_002563214.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.386(Affirmative) YP_002563215.1 psort: bacterial cytoplasm --- Certainty= 0.525(Affirmative); COG1722 XseB Exonuclease VII small subunit YP_002563216.1 posrt: bacterial cytoplasm --- Certainty= 0.097(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins YP_002563217.1 psort: bacterial outer membrane --- Certainty= 0.941(Affirmative); COG3504 VirB9 Type IV secretory pathway, VirB9 components YP_002563218.1 psort: bacterial cytoplasm --- Certainty= 0.268(Affirmative); COG1071 AcoA Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit YP_002563219.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_002563220.1 psort: bacterial inner membrane --- Certainty= 0.115(Affirmative); COG0516 GuaB IMP dehydrogenase/GMP reductase YP_002563221.1 catalyzes the phosphorylation of NAD to NADP YP_002563222.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002563223.1 psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD ACP S-malonyltransferase YP_002563224.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002563225.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.554(Affirmative); COG0477 Permeases of the major facilitator superfamily YP_002563226.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.300(Affirmative) YP_002563227.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002563228.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.922(Affirmative); COG1651 Protein-disulfide isomerase YP_002563229.1 mitochondrial processing protease; psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0612 PqqL predicted Zn-dependent peptidases YP_002563230.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.210(Affirmative); COG0739 Membrane proteins related to metalloendopeptidases YP_002563231.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.095(Affirmative); COG2070 Dioxygenases related to 2-nitropropane dioxygenase YP_002563232.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002563233.1 member of msp1b gene family, full length gene copy 2; member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.285(Affirmative) YP_002563234.1 member of msp1b gene family, partial gene 2; member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.227(Affirmative) YP_002563235.1 psort: bacterial inner membrane --- Certainty= 0.100(Affirmative); COG1197 Mfd transcription-repair coupling factor - superfamily II helicase YP_002563236.1 psort: bacterial inner membrane --- Certainty= 0.276(Affirmative); COG0328 RnhA ribonuclease HI YP_002563237.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.317(Affirmative) YP_002563238.1 Catalyzes the phosphorylation of UMP to UDP YP_002563239.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002563240.1 psort: bacterial inner membrane --- Certainty= 0.382(Affirmative); COG0020 UppS undecaprenyl pyrophosphate synthase YP_002563241.1 COG0575 CdsA CDP-diglyceride synthetase YP_002563242.1 member of msp1b gene family, partial gene 3; member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.227(Affirmative) YP_002563243.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.136(Affirmative) YP_002563244.1 psort: bacterial cytoplasm --- Certainty= 0.378(Affirmative); COG0152 PurC phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthase YP_002563245.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002563246.1 psort: bacterial inner membrane --- Certainty= 0.533(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.922 Max cleavage site probability: 0.842 between pos. 21 and 22; COG0526 TrxA Thiol-disulfide isomerase and thioredoxins YP_002563247.1 psort: bacterial inner membrane --- Certainty= 0.444(Affirmative); COG3175 COX11 cytochrome oxidase assembly factor YP_002563248.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002563249.1 ATP-binding protein; required for proper cytochrome c maturation YP_002563250.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002563251.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002563252.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.141(Affirmative) YP_002563253.1 psort: bacterial cytoplasm --- Certainty= 0.427(Affirmative); COG1278 CspC cold shock proteins YP_002563254.1 psort: bacterial inner membrane --- Certainty= 0.567(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.998 Max cleavage site probability: 0.704 between pos. 32 and 33; COG0347 GlnK nitrogen regulatory protein PII YP_002563255.1 psort: bacterial inner membrane --- Certainty= 0.035(Affirmative); COG0349 Rnd ribonuclease D YP_002563256.1 psort: bacterial inner membrane --- Certainty= 0.191(Affirmative); COG0272 Lig NAD-dependent DNA ligase YP_002563257.1 psort: bacterial cytoplasm --- Certainty= 0.297(Affirmative) YP_002563258.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0271 BolA Stress-induced morphogen (activity unknown) YP_002563259.1 psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG0526 TrxA Thiol-disulfide isomerase and thioredoxins YP_002563260.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002563261.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.576(Affirmative); COG1593 Integral membrane protein, possible transporter YP_002563262.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.465(Affirmative) YP_002563263.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002563264.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002563265.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002563266.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002563267.1 psort: bacterial cytoplasm --- Certainty= 0.285(Affirmative); COG2114 CyaA Adenylate cyclase, family 3 (some proteins contain HAMP domain) YP_002563268.1 psort: bacterial inner membrane --- Certainty= 0.397(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component YP_002563269.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002563270.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002563271.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_002563272.1 psort: bacterial inner membrane --- Certainty= 0.459(Affirmative) YP_002563273.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002563274.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002563275.1 psort: bacterial inner membrane --- Certainty= 0.395(Affirmative); COG0755 CcmC ABC-type transport system involved in cytochrome c biogenesis, permease component YP_002563276.1 psort: bacterial cytoplasm --- Certainty= 0.266(Affirmative); COG0194 Gmk guanylate kinase YP_002563277.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.319(Affirmative); COG0726 Predicted xylanase/chitin deacetylase YP_002563278.1 psort: bacterial cytoplasm --- Certainty= 0.295(Affirmative); COG0190 FolD 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase YP_002563279.1 member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.227(Affirmative) YP_002563280.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.179(Affirmative) YP_002563281.1 member of msp1 superfamily; msp1B partial gene 1; psort: bacterial inner membrane --- Certainty= 0.266(Affirmative) YP_002563282.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.151(Affirmative); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_002563283.1 psort: bacterial inner membrane --- Certainty= 0.412(Affirmative); COG3303 NrfA formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit YP_002563284.1 psort: bacterial inner membrane --- Certainty= 0.463(Affirmative); COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA subunit YP_002563285.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002563286.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.389(Affirmative) YP_002563287.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.075(Affirmative); COG0546 Predicted phosphatases YP_002563288.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002563289.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.808(Affirmative) bacterial outer membrane --- Certainty= 0.790(Affirmative); COG2823 Predicted periplasmic or secreted lipoprotein YP_002563290.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002563291.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002563292.1 psort: bacterial cytoplasm --- Certainty= 0.174(Affirmative); COG1589 FtsQ cell division septal protein YP_002563293.1 psort: bacterial cytoplasm --- Certainty= 0.262(Affirmative); COG3852 NtrB signal transduction histidine kinase, nitrogen specific YP_002563294.1 member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 1.000 Max cleavage site probability: 0.875 between pos. 28 and 29 YP_002563295.1 psort: bacterial inner membrane --- Certainty= 0.117(Affirmative) YP_002563296.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.643(Affirmative) YP_002563297.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.355(Affirmative) YP_002563298.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.646(Affirmative) YP_002563299.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.701(Affirmative) bacterial outer membrane --- Certainty= 0.317(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.741 Max cleavage site probability: 0.700 between pos. 27 and 28 YP_002563300.1 psort: bacterial cytoplasm --- Certainty= 0.098(Affirmative); COG1235 PhnP Metal-dependent hydrolases of the beta-lactamase superfamily I YP_002563301.1 psort: bacterial cytoplasm --- Certainty= 0.125(Affirmative); COG0174 GlnA glutamine synthase YP_002563302.1 psort: bacterial inner membrane --- Certainty= 0.586(Affirmative); COG0573 PstC ABC-type phosphate transport system, permease component YP_002563303.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002563304.1 psort: bacterial inner membrane --- Certainty= 0.153(Affirmative); COG0074 SucD succinyl-CoA synthetase alpha subunit YP_002563305.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002563306.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002563307.1 psort: bacterial outer membrane --- Certainty= 0.239(Affirmative) bacterial periplasmic space --- Certainty= 0.239(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.984 Max cleavage site probability: 0.934 between pos. 20 and 21; COG0226 ABC-type phosphate transport system, periplasmic component YP_002563308.1 psort: bacterial inner membrane --- Certainty= 0.391(Affirmative); signalP: Prediction: Signal peptide Signal peptide probability: 0.837 Max cleavage site probability: 0.403 between pos. 26 and 27 YP_002563309.1 psort: bacterial cytoplasm --- Certainty= 0.022(Affirmative) YP_002563310.1 COG3038 CybB cytochrome B561 YP_002563311.1 psort: bacterial inner membrane --- Certainty= 0.673(Affirmative) YP_002563312.1 psort: bacterial inner membrane --- Certainty= 0.569(Affirmative); COG1404 aprE subtilisin-like serine proteases YP_002563313.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.326(Affirmative) YP_002563314.1 psort: bacterial periplasmic space --- Certainty= 0.738(Affirmative); COG0771 MurD UDP-N-acetylmuramoylalanine-D-glutamate ligase YP_002563315.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002563316.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.172(Affirmative); COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily YP_002563317.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.486(Affirmative) YP_002563318.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.727(Affirmative) YP_002563319.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002563320.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002563321.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002563322.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002563323.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002563324.1 psort: bacterial cytoplasm --- Certainty= 0.245(Affirmative); COG0250 NusG transcription antiterminator YP_002563325.1 binds directly to 23S ribosomal RNA YP_002563326.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002563327.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002563328.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002563329.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002563330.1 psort: bacterial inner membrane --- Certainty= 0.168(Affirmative); COG0086 RpoC DNA-directed RNA polymerase beta' subunit/160 kD subunit YP_002563331.1 psort: bacterial inner membrane --- Certainty= 0.183(Affirmative); COG0164 RnhB ribonuclease HII YP_002563332.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative) YP_002563333.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.306(Affirmative); COG1238 Uncharacterized membrane protein YP_002563334.1 psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes YP_002563335.1 Na+/H+ antiporter; psort: bacterial inner membrane --- Certainty= 0.249(Affirmative) YP_002563336.1 called by Glimmer 2; type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_002563337.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002563338.1 psort: bacterial cytoplasm --- Certainty= 0.464(Affirmative); COG0242 Def N-formylmethionyl-tRNA deformylase YP_002563339.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.130(Affirmative); COG0400 Predicted esterase YP_002563340.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.370(Affirmative); COG3621 Patatin YP_002563341.1 psort: bacterial cytoplasm --- Certainty= 0.034(Affirmative); COG0259 PdxH pyridoxamine phosphate oxidase YP_002563342.1 psort: bacterial inner membrane --- Certainty= 0.153(Affirmative); COG0769 MurE UDP-N-acetylmuramyl tripeptide synthase YP_002563343.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative) YP_002563344.1 psort: bacterial inner membrane --- Certainty= 0.236(Affirmative); COG0626 cystathionine beta-lyases/cystathionine gamma-synthases YP_002563345.1 psort: bacterial inner membrane --- Certainty= 0.036(Affirmative); COG0271 BolA stress-induced morphogen (activity unknown) YP_002563346.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.204(Affirmative) YP_002563347.1 psort: bacterial inner membrane --- Certainty= 0.113(Affirmative); COG0587 DnaE DNA polymerase III alpha subunit YP_002563348.1 psort: bacterial inner membrane --- Certainty= 0.257(Affirmative); COG0128 AroA 5-enolpyruvylshikimate-3-phosphate synthase YP_002563349.1 psort: bacterial inner membrane --- Certainty= 0.508(Affirmative); COG2009 SdhC succinate dehydrogenase/fumarate reductase cytochrome b subunit YP_002563350.1 psort: bacterial inner membrane --- Certainty= 0.408(Affirmative); COG2142 SdhD succinate dehydrogenase hydrophobic anchor subunit YP_002563351.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.206(Affirmative) YP_002563352.1 psort: bacterial inner membrane --- Certainty= 0.206(Affirmative); COG0351 ThiD hydroxymethylpyrimidine/phosphomethylpyrimidine kinase YP_002563353.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.237(Affirmative); COG0593 ATPase involved in DNA replication initiation YP_002563354.1 psort: bacterial inner membrane --- Certainty= 0.531(Affirmative); COG0628 PerM predicted permease YP_002563355.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.377(Affirmative); COG2975 Uncharacterized BCR YP_002563356.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002563357.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.559(Affirmative); COG2202 PAS/PAC domain YP_002563358.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.201(Affirmative) YP_002563359.1 psort: bacterial inner membrane --- Certainty= 0.414(Affirmative); COG1267 PgpA phosphatidlglycerophosphatase A YP_002563360.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.370(Affirmative) YP_002563361.1 psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0544 Tig FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) YP_002563362.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002563363.1 binds and unfolds substrates as part of the ClpXP protease YP_002563364.1 psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0466 Lon ATP-dependent Lon protease, bacterial type YP_002563365.1 psort: bacterial inner membrane --- Certainty= 0.179(Affirmative); COG0223 Fmt methionyl-tRNA formyltransferase YP_002563366.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.011(Affirmative); COG1054 Uncharacterized enzyme related to sulfurtransferases YP_002563367.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.443(Affirmative); COG1806 Uncharacterized BCR YP_002563368.1 psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0352 ThiE thiamine monophosphate synthase YP_002563369.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.329(Affirmative); COG1253 Hemolysins and related proteins containing CBS domains YP_002563370.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.196(Affirmative); COG0762 Predicted integral membrane protein YP_002563371.1 psort: bacterial inner membrane --- Certainty= 0.291(Affirmative); COG1674 FtsK DNA segregation ATPase FtsK/SpoIIIE and related proteins YP_002563372.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.321(Affirmative) YP_002563373.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_002563374.1 psort: bacterial inner membrane --- Certainty= 0.582(Affirmative); COG0642 BaeS signal transduction histidine kinase YP_002563375.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.919(Affirmative) YP_002563376.1 psort: bacterial inner membrane --- Certainty= 0.537(Affirmative); COG0848 ExbD biopolymer transport protein YP_002563377.1 psort: bacterial inner membrane --- Certainty= 0.378(Affirmative); COG0811 TolQ biopolymer transport protein YP_002563378.1 psort: bacterial inner membrane --- Certainty= 0.130(Affirmative); COG0323 MutL DNA mismatch repair enzyme (predicted ATPase) YP_002563379.1 psort: bacterial cytoplasm --- Certainty= 0.158(Affirmative); COG0758 Smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake YP_002563380.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002563381.1 psort: bacterial inner membrane --- Certainty= 0.170(Affirmative); COG2805 Predicted ATPases involved in pili biogenesis, PilT homologs YP_002563382.1 psort: bacterial inner membrane --- Certainty= 0.187(Affirmative); COG0304 FabB 3-oxoacyl-ACP synthase YP_002563383.1 psort: bacterial inner membrane --- Certainty= 0.070(Affirmative); COG0236 AcpP acyl carrier protein YP_002563384.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002563385.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Similar to genes annotated as pgpA in E. ruminantium; psort: bacterial inner membrane --- Certainty= 0.455(Affirmative) YP_002563386.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.164(Affirmative); COG1495 Disulfide bond formation protein DsbB YP_002563387.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.279(Affirmative) YP_002563388.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.372(Affirmative) YP_002563389.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.330(Affirmative) YP_002563390.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.102(Affirmative) YP_002563391.1 psort: bacterial cytoplasm --- Certainty= 0.080(Affirmative); COG2941 CAT5 ubiquinone biosynthesis protein COQ7 YP_002563392.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.217(Affirmative) YP_002563393.1 Hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.920(Affirmative) YP_002563394.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.153(Affirmative) YP_002563395.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.138(Affirmative) YP_002563396.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative) YP_002563397.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.126(Affirmative) YP_002563398.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.117(Affirmative) YP_002563399.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.293(Affirmative) YP_002563400.1 psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0210 UvrD superfamily I DNA and RNA helicases YP_002563401.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.461(Affirmative) YP_002563402.1 negatively supercoils closed circular double-stranded DNA YP_002563403.1 psort: bacterial cytoplasm --- Certainty= 0.535(Affirmative); COG0177 Nth predicted EndoIII-related endonuclease YP_002563404.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.939(Affirmative) YP_002563405.1 molecular chaperone YP_002563406.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.044(Affirmative) YP_002563407.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.377(Affirmative) YP_002563408.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002563409.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002563410.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.314(Affirmative) YP_002563411.1 psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase YP_002563412.1 psort: bacterial cytoplasm --- Certainty= 0.290(Affirmative); COG0625 Gst glutathione-S-transferases YP_002563413.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.164(Affirmative) YP_002563414.1 psort: bacterial cytoplasm --- Certainty= 0.231(Affirmative); COG3842 PotA ABC-type spermidine/putrescine transport systems, ATPase components YP_002563415.1 psort: bacterial inner membrane --- Certainty= 0.053(Affirmative); COG0353 RecR recombinational DNA repair protein (RecF pathway) YP_002563416.1 psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0803 ZnuA ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding (lipo)protein (surface adhesin A) YP_002563417.1 psort: bacterial inner membrane --- Certainty= 0.179(Affirmative); COG1121 ZnuC ABC-type Mn/Zn transport systems, ATPase component YP_002563418.1 psort: bacterial inner membrane --- Certainty= 0.716(Affirmative); COG0543 UbiB 2-polyprenylphenol hydroxylase YP_002563419.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.493(Affirmative) YP_002563420.1 psort: bacterial cytoplasm --- Certainty= 0.196(Affirmative); COG0621 MiaB 2-methylthioadenine synthetase YP_002563421.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.020(Affirmative) YP_002563422.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.629(Affirmative) YP_002563423.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002563424.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.280(Affirmative) YP_002563425.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002563426.1 psort: bacterial cytoplasm --- Certainty= 0.185(Affirmative) YP_002563427.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.143(Affirmative) YP_002563428.1 This protein performs the mismatch recognition step during the DNA repair process YP_002563429.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.160(Affirmative) YP_002563430.1 High sequence identity to AMF_304 and AMF_309 psort: bacterial inner membrane --- Certainty= 0.518(Affirmative); COG0477 ProP Permeases of the major facilitator superfamily YP_002563431.1 High sequence identity to AMF_303 and AMF_309 Higher sequence similarity to other Anaplasmataceae than AMF_303, lower than AMF_309; psort: bacterial inner membrane --- Certainty= 0.554(Affirmative); COG0477 ProP Permeases of the major facilitator superfamily YP_002563432.1 psort: bacterial inner membrane --- Certainty= 0.172(Affirmative); COG0171 NadE NAD synthase YP_002563433.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002563434.1 psort: bacterial inner membrane --- Certainty= 0.516(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2 YP_002563435.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.274(Affirmative) YP_002563436.1 High sequence identity to AMF_303 and AMF_304 Higher sequence similarity to other Anaplasmataceae than AMF_303 and AMF_304; psort: bacterial inner membrane --- Certainty= 0.603(Affirmative); COG0477 ProP Permeases of the major facilitator superfamily YP_002563437.1 psort: bacterial cytoplasm --- Certainty= 0.082(Affirmative); COG0629 Ssb single-stranded DNA-binding protein YP_002563438.1 psort: bacterial cytoplasm --- Certainty= 0.142(Affirmative) YP_002563439.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002563440.1 psort: bacterial cytoplasm --- Certainty= 0.069(Affirmative); COG0623 FabI enoyl-ACP reductase (NADH) YP_002563441.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002563442.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.450(Affirmative) YP_002563443.1 psort: bacterial inner membrane --- Certainty= 0.268(Affirmative); COG1057 NadD Nicotinic acid mononucleotide adenylyltransferase YP_002563444.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002563445.1 psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0776 HimA Bacterial nucleoid DNA-binding protein YP_002563446.1 psort: bacterial cytoplasm --- Certainty= 0.235(Affirmative); COG2812 DnaX DNA polymerase III, gamma/tau subunits YP_002563447.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.026(Affirmative); COG0009 translation factor (SUA5) YP_002563448.1 psort: bacterial periplasmic space --- Certainty= 0.923(Affirmative); COG0237 CoaE dephospho-CoA kinase YP_002563449.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002563450.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.298(Affirmative); COG2840 Uncharacterized BCR YP_002563451.1 psort: bacterial cytoplasm --- Certainty= 0.135(Affirmative); COG1758 RpoZ DNA-directed RNA polymerase subunit K/omega YP_002563452.1 psort: bacterial cytoplasm --- Certainty=0.133(Affirmative) YP_002563453.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002563454.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.333(Affirmative); COG0084 Mg-dependent DNase YP_002563455.1 psort: bacterial inner membrane --- Certainty= 0.196(Affirmative); COG0284 PyrF orotidine-5'-phosphate decarboxylase YP_002563456.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002563457.1 psort: bacterial inner membrane --- Certainty= 0.249(Affirmative); COG0496 SurE survival protein, predicted acid phosphatase YP_002563458.1 psort: bacterial cytoplasm --- Certainty= 0.333(Affirmative); COG0852 NuoC NADH:ubiquinone oxidoreductase 27 kD subunit YP_002563459.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002563460.1 psort: bacterial inner membrane --- Certainty= 0.510(Affirmative); COG0838 NuoA NADH:ubiquinone oxidoreductase subunit 3 (chain A) YP_002563461.1 psort: bacterial cytoplasm --- Certainty= 0.286(Affirmative); COG0178 UvrA excinuclease ATPase subunit YP_002563462.1 psort: bacterial inner membrane --- Certainty= 0.164(Affirmative); COG0781 NusB transcription termination factor YP_002563463.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002563464.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002563465.1 psort: bacterial inner membrane --- Certainty= 0.469(Affirmative); COG1183 PssA phosphatidylserine synthase YP_002563466.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_002563467.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.302(Affirmative); COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases YP_002563468.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.248(Affirmative) YP_002563469.1 psort: bacterial inner membrane --- Certainty= 0.187(Affirmative); COG0707 MurG UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase YP_002563470.1 psort: bacterial cytoplasm --- Certainty= 0.218(Affirmative); COG0231 Efp translation elongation factor P/translation initiation factor eIF-5A YP_002563471.1 psort: bacterial inner membrane --- Certainty= 0.100(Affirmative); COG0483 SuhB Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family YP_002563472.1 psort: bacterial inner membrane --- Certainty= 0.174(Affirmative); COG0564 RluA pseudouridylate synthases, 23S RNA-specific YP_002563473.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP YP_002563474.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative) YP_002563475.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.013(Affirmative) YP_002563476.1 Possible frameshift with AMF_351; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG2902 NAD-specific glutamate dehydrogenase YP_002563477.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.194(Affirmative) YP_002563478.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002563479.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002563480.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins YP_002563481.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.126(Affirmative) YP_002563482.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.186(Affirmative); COG1565 Uncharacterized ACR YP_002563483.1 psort: bacterial inner membrane --- Certainty= 0.183(Affirmative); COG0358 DnaG DNA primase (bacterial type) YP_002563484.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.327(Affirmative) YP_002563485.1 Possible frameshift with AMF_362; psort: bacterial inner membrane --- Certainty= 0.117(Affirmative); COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32) YP_002563486.1 psort: bacterial cytoplasm --- Certainty= 0.034(Affirmative); COG0042 Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family YP_002563487.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002563488.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.036(Affirmative) YP_002563489.1 psort: bacterial cytoplasm --- Certainty= 0.170(Affirmative); COG1324 CutA uncharacterized protein involved in tolerance to divalent cations YP_002563490.1 psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase YP_002563491.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.130(Affirmative); COG0500 SAM-dependent methyltransferases YP_002563492.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.388(Affirmative) YP_002563493.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.183(Affirmative); COG0063 Predicted sugar kinase YP_002563494.1 psort: bacterial cytoplasm --- Certainty= 0.362(Affirmative); COG0550 TopA topoisomerase IA YP_002563495.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.770(Affirmative) YP_002563496.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002563497.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002563498.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.805(Affirmative) YP_002563499.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002563500.1 psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative); COG0492 TrxB thioredoxin reductase YP_002563501.1 psort: bacterial cytoplasm --- Certainty= 0.065(Affirmative); COG0450 AhpC peroxiredoxin YP_002563502.1 psort: bacterial cytoplasm --- Certainty= 0.178(Affirmative); COG0075 - serine-pyruvate aminotransferase/archaeal aspartate aminotransferase YP_002563503.1 psort: bacterial inner membrane --- Certainty= 0.601(Affirmative); COG0760 SurA Parvulin-like peptidyl-prolyl isomerase YP_002563504.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.014(Affirmative); COG1214 Inactive homologs of metal-dependent proteases, molecular chaperones YP_002563505.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.561(Affirmative) YP_002563507.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002563508.1 functions in MreBCD complex in some organisms YP_002563509.1 psort: bacterial cytoplasm --- Certainty= 0.231(Affirmative); COG0130 TruB pseudouridine synthase YP_002563510.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002563511.1 psort: bacterial inner membrane --- Certainty= 0.287(Affirmative); COG0005 Pnp purine nucleoside phosphorylase YP_002563512.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.264(Affirmative); COG0500 SAM-dependent methyltransferases YP_002563513.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002563514.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.397(Affirmative) YP_002563515.1 member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.567(Affirmative) YP_002563516.1 member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.667(Affirmative) YP_002563517.1 member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.546(Affirmative) YP_002563518.1 member of msp1 superfamily; psort: bacterial inner membrane --- Certainty= 0.563(Affirmative) YP_002563519.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.635(Affirmative) YP_002563520.1 Hypothetical protein called by Glimmer 2; Some similarity to AMF_408 and to AMF_395; psort: bacterial inner membrane --- Certainty= 0.688(Affirmative) YP_002563521.1 Hypothetical protein called by Glimmer 2; Some similarity to AMF_408; psort: bacterial cytoplasm --- Certainty= 0.324(Affirmative) YP_002563522.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_405, AMF_406, AMF_407, AMF_408 psort: bacterial inner membrane --- Certainty= 0.452(Affirmative) YP_002563523.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_403, AMF_406, AMF_407, AMF_404 psort: bacterial periplasmic space --- Certainty= 0.950(Affirmative) YP_002563524.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.053(Affirmative) YP_002563525.1 Hypothetical protein called by Glimmer 2; Significant sequence similarity with AMF_405, AMF_403, AMF_407, and AMF_404 .; psort: bacterial inner membrane --- Certainty= 0.699(Affirmative) YP_002563526.1 Hypothetical protein called by Glimmer 2; Significant sequence similarity to AMF_406, AMF_405, AMF_403, and AMF_404 .; psort: bacterial periplasmic space --- Certainty= 0.839(Affirmative) YP_002563527.1 Hypothetical protein called by Glimmer 2; Significant sequence similarity with AMF_402, AMF_401, and AMF_403 .; psort: bacterial inner membrane --- Certainty= 0.722(Affirmative) YP_002563528.1 psort: bacterial cytoplasm --- Certainty= 0.093(Affirmative); COG0611 ThiL thiamine monophosphate kinase YP_002563529.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.739(Affirmative); COG1295 Predicted multitransmembrane protein YP_002563530.1 psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002563531.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.154(Affirmative) YP_002563532.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002563533.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002563534.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; C-terminal end matches AMF_428.; psort: bacterial periplasmic space --- Certainty= 0.294(Affirmative); COG2358 Predicted periplasmic binding protein YP_002563535.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002563536.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.463(Affirmative); COG1714 Uncharacterized membrane protein/domain YP_002563537.1 psort: bacterial inner membrane --- Certainty= 0.033(Affirmative); COG1539 FolB dihydroneopterin aldolase YP_002563538.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_002563539.1 psort: bacterial cytoplasm --- Certainty= 0.326(Affirmative); COG2227 UbiG 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase YP_002563540.1 psort: bacterial cytoplasm --- Certainty= 0.078(Affirmative); COG0532 translation initiation factor 2 (GTPase) YP_002563541.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.197(Affirmative) YP_002563542.1 psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0698 ribose 5-phosphate isomerase YP_002563543.1 Involved in ubiquinone biosynthesis YP_002563544.1 Appears to be a truncated version of AMF_418; psort: bacterial inner membrane --- Certainty= 0.259(Affirmative); COG0533 QRI7 Metal-dependent proteases with possible chaperone activity YP_002563545.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; 65/65 identities with the C-terminal end of AMF_417 (from AA 275-339); psort: bacterial cytoplasm --- Certainty= 0.077(Affirmative); COG2358 Predicted periplasmic binding protein YP_002563546.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.274(Affirmative) YP_002563547.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.361(Affirmative) YP_002563548.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.272(Affirmative) YP_002563549.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.161(Affirmative) YP_002563550.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.183(Affirmative) YP_002563551.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.292(Affirmative) YP_002563552.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_002563553.1 psort: bacterial inner membrane --- Certainty= 0.179(Affirmative); COG1028 FabG dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases YP_002563554.1 N-terminal end of AMF_435 (putA).; psort: bacterial cytoplasm --- Certainty= 0.539(Affirmative); COG1012 PutA NAD-dependent aldehyde dehydrogenase YP_002563555.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.310(Affirmative) YP_002563556.1 psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative); COG0797 RlpA lipoproteins YP_002563557.1 psort: bacterial cytoplasm --- Certainty= 0.293(Affirmative); COG0708 XthA exonuclease III YP_002563558.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.138(Affirmative) YP_002563559.1 psort: bacterial cytoplasm --- Certainty= 0.021(Affirmative); COG0257 RpmJ ribosomal protein L36 YP_002563560.1 Conserved family - Septum formation initiator; psort: bacterial inner membrane --- Certainty= 0.399(Affirmative) YP_002563561.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.503(Affirmative) YP_002563562.1 involved in the peptidyltransferase reaction during translation YP_002563563.1 psort: bacterial cytoplasm --- Certainty= 0.280(Affirmative); COG0261 RplU ribosomal protein L21 YP_002563564.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002563565.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002563566.1 C-terminal end of the full-length purA; psort: bacterial cytoplasm --- Certainty= 0.325(Affirmative); COG0104 PurA Adenylosuccinate synthase YP_002563567.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.266(Affirmative) YP_002563568.1 psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis YP_002563569.1 psort: bacterial cytoplasm --- Certainty= 0.396(Affirmative); COG0212 5-formyltetrahydrofolate cyclo-ligase YP_002563570.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative) YP_002563571.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.359(Affirmative) YP_002563572.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.423(Affirmative) YP_002563573.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.614(Affirmative) YP_002563574.1 psort: bacterial inner membrane --- Certainty= 0.170(Affirmative); COG0492 TrxB thioredoxin reductase YP_002563575.1 psort: bacterial cytoplasm --- Certainty= 0.121(Affirmative); COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs YP_002563576.1 psort: bacterial inner membrane --- Certainty= 0.174(Affirmative); COG0302 FolE GTP cyclohydrolase I YP_002563577.1 psort: bacterial cytoplasm --- Certainty= 0.154(Affirmative); COG0224 AtpG F0F1-type ATP synthase gamma subunit YP_002563578.1 Catalyzes the transfer of electrons from NADH to quinone YP_002563579.1 Catalyzes the transfer of electrons from NADH to quinone YP_002563580.1 psort: bacterial cytoplasm --- Certainty= 0.219(Affirmative); COG0847 DnaQ DNA polymerase III epsilon subunit and related 3'-5' exonucleases YP_002563581.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.102(Affirmative); COG0606 Predicted ATPase with chaperone activity YP_002563582.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.924(Affirmative) YP_002563583.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.497(Affirmative) YP_002563584.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.358(Affirmative) YP_002563585.1 psort: bacterial cytoplasm --- Certainty= 0.052(Affirmative); COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32) YP_002563586.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.307(Affirmative) YP_002563587.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.122(Affirmative) YP_002563588.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.192(Affirmative) YP_002563589.1 Catalyzes the transfer of electrons from NADH to quinone YP_002563590.1 Catalyzes the transfer of electrons from NADH to quinone YP_002563591.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.578(Affirmative) YP_002563592.1 psort: bacterial inner membrane --- Certainty= 0.115(Affirmative); COG0187 GyrB DNA gyrase (topoisomerase II) B subunit YP_002563593.1 psort: bacterial inner membrane --- Certainty= 0.100(Affirmative); COG0163 UbiX 3-polyprenyl-4-hydroxybenzoate decarboxylase YP_002563594.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.310(Affirmative); COG3088 Uncharacterized protein involved in biosynthesis of c-type cytochromes YP_002563595.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.323(Affirmative) YP_002563596.1 psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0633 Fdx ferredoxin YP_002563597.1 psort: bacterial inner membrane --- Certainty= 0.111(Affirmative); COG0443 DnaK molecular chaperone YP_002563598.1 psort: bacterial cytoplasm --- Certainty= 0.094(Affirmative); COG1076 DjlA DnaJ-domain-containing proteins 1 YP_002563599.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.215(Affirmative); COG0316 Uncharacterized ACR YP_002563600.1 psort: bacterial cytoplasm --- Certainty= 0.150(Affirmative); COG0822 IscU NifU homologs involved in Fe-S cluster formation YP_002563601.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002563602.1 duplicated gene; Similar to AMF_489; psort: bacterial inner membrane --- Certainty= 0.119(Affirmative); COG1104 cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes YP_002563603.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.242(Affirmative); COG2945 Predicted hydrolase of the alpha/beta superfamily YP_002563604.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_002563605.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative) YP_002563606.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002563607.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002563608.1 called by Glimmer 2; similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_002563609.1 psort: bacterial inner membrane --- Certainty= 0.162(Affirmative); COG0355 AtpC F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit) YP_002563610.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002563611.1 psort: bacterial inner membrane --- Certainty= 0.444(Affirmative); COG2239 MgtE Mg/Co/Ni transporter MgtE (contains CBS domain) YP_002563612.1 psort: bacterial cytoplasm --- Certainty= 0.172(Affirmative); COG0293 FtsJ methyltransferase involved in cell division YP_002563613.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_504; psort: bacterial periplasmic space --- Certainty= 0.939(Affirmative) YP_002563614.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_503, the middle of AMF_735; psort: bacterial inner membrane --- Certainty= 0.501(Affirmative) YP_002563615.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_209, AMF_571, AMF_735, and AMF_790 .; psort: bacterial inner membrane --- Certainty= 0.539(Affirmative) YP_002563616.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Inverted from St. Maries; psort: bacterial inner membrane --- Certainty= 0.469(Affirmative) YP_002563617.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_505, AMF_571, AMF_735, AMF_790 .; psort: bacterial inner membrane --- Certainty= 0.862(Affirmative) YP_002563618.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002563619.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002563620.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative) YP_002563621.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.072(Affirmative) YP_002563622.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.680(Affirmative) YP_002563623.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_002563624.1 psort: bacterial cytoplasm --- Certainty= 0.340(Affirmative); COG1225 Bcp Peroxiredoxin YP_002563625.1 called by Glimmer 2; in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002563626.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.327(Affirmative) YP_002563627.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.556(Affirmative) YP_002563628.1 psort: bacterial cytoplasm --- Certainty= 0.384(Affirmative); COG1186 PrfB protein chain release factor B YP_002563629.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0217 Uncharacterized ACR YP_002563630.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002563631.1 psort: bacterial inner membrane --- Certainty= 0.095(Affirmative); COG0285 FolC folylpolyglutamate synthase YP_002563632.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002563633.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002563634.1 psort: bacterial cytoplasm --- Certainty= 0.332(Affirmative); COG0666 Arp ankyrin repeat proteins YP_002563635.1 Catalyzes the transfer of electrons from NADH to quinone YP_002563636.1 psort: bacterial inner membrane --- Certainty= 0.147(Affirmative); COG0681 LepB signal peptidase I YP_002563637.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.161(Affirmative); COG0316 Uncharacterized ACR YP_002563638.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.172(Affirmative) YP_002563639.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.092(Affirmative) YP_002563640.1 psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563641.1 psort: bacterial outer membrane --- Certainty= 0.676(Affirmative) YP_002563642.1 psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563643.1 psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG1217 TypA predicted membrane GTPase involved in stress response YP_002563644.1 psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative); COG0542 ClpA ATPases with chaperone activity, ATP-binding subunit YP_002563645.1 psort: bacterial inner membrane --- Certainty= 0.607(Affirmative); COG0861 membrane protein TerC, possibly involved in tellurium resistance YP_002563646.1 psort: bacterial cytoplasm --- Certainty= 0.191(Affirmative); COG0858 RbfA ribosome-binding factor A YP_002563647.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002563648.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002563649.1 psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG0841 AcrB cation/multidrug efflux pump YP_002563650.1 psort: bacterial inner membrane --- Certainty= 0.525(Affirmative); COG0805 TatC Sec-independent protein secretion pathway component TatC YP_002563651.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002563652.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.217(Affirmative) YP_002563653.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002563654.1 psort: bacterial inner membrane --- Certainty= 0.650(Affirmative); COG1007 NuoN NADH:ubiquinone oxidoreductase subunit 2 (chain N) YP_002563655.1 psort: bacterial inner membrane --- Certainty= 0.711(Affirmative); COG1008 NuoM NADH:ubiquinone oxidoreductase subunit 4 (chain M) YP_002563656.1 psort: bacterial inner membrane --- Certainty= 0.576(Affirmative); COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit YP_002563657.1 psort: bacterial inner membrane --- Certainty= 0.573(Affirmative); COG0713 NuoK NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) YP_002563658.1 psort: bacterial inner membrane --- Certainty= 0.650(Affirmative); COG0839 NuoJ NADH:ubiquinone oxidoreductase subunit 6 (chain J) YP_002563659.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_002563660.1 psort: bacterial inner membrane --- Certainty= 0.005(Affirmative); COG1250 FadB 3-hydroxyacyl-CoA dehydrogenase YP_002563661.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.287(Affirmative) YP_002563662.1 psort: bacterial cytoplasm --- Certainty= 0.059(Affirmative); COG0324 MiaA tRNA delta(2)-isopentenylpyrophosphate transferase YP_002563663.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB8); psort: bacterial inner membrane --- Certainty= 0.510(Affirmative) YP_002563664.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.304(Affirmative); Uncharacterized BCR YP_002563665.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002563666.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.416(Affirmative) YP_002563667.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002563668.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002563669.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002563670.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002563671.1 psort: bacterial inner membrane --- Certainty= 0.042(Affirmative); COG0825 AccA Acetyl-CoA carboxylase alpha subunit YP_002563672.1 psort: bacterial cytoplasm --- Certainty= 0.249(Affirmative); COG0266 Nei formamidopyrimidine-DNA glycosylase YP_002563673.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_505, AMF_735, AMF_509, AMF_509, and AMF_790 .; psort: bacterial inner membrane --- Certainty= 0.586(Affirmative) YP_002563674.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002563675.1 Hypothetical protein called by Glimmer 2; similar to the middle of AMF_507 (AAs 505 to 577).; psort: bacterial cytoplasm --- Certainty= 0.154(Affirmative) YP_002563676.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.925(Affirmative) YP_002563677.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.936(Affirmative) YP_002563678.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; AMF577 appears to be a duplication of the C terminal end of this gene.; psort: bacterial inner membrane --- Certainty= 0.196(Affirmative) YP_002563679.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Appears to be a duplication of the C-terminal end of AMF_576 .; psort: bacterial inner membrane --- Certainty= 0.225(Affirmative) YP_002563680.1 psort: bacterial inner membrane --- Certainty= 0.317(Affirmative); COG2857 CYT1 cytochrome c1 YP_002563681.1 psort: bacterial inner membrane --- Certainty= 0.495(Affirmative); COG3658 - cytochrome b YP_002563682.1 psort: bacterial inner membrane --- Certainty= 0.217(Affirmative); split domain; COG0723 QcrA Rieske Fe-S protein YP_002563683.1 psort: bacterial cytoplasm --- Certainty= 0.295(Affirmative); split domain; COG0723 QcrA Rieske Fe-S protein YP_002563684.1 Hypothetical protein called by Glimmer 2; psort: bacterial membrane --- Certainty= 0.421(Affirmative) YP_002563685.1 psort: bacterial inner membrane --- Certainty= 0.590(Affirmative); COG1108 ZnuB ABC-type Mn2+/Zn2+ transport systems, permease components YP_002563686.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.154(Affirmative) YP_002563687.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002563688.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002563689.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002563690.1 psort: bacterial cytoplasm --- Certainty= 0.174(Affirmative); COG0424 Maf nucleotide-binding protein implicated in inhibition of septum formation YP_002563691.1 psort: bacterial cytoplasm --- Certainty= 0.244(Affirmative); COG0845 AcrA Membrane-fusion protein YP_002563692.1 psort: bacterial membrane --- Certainty= 0.512(Affirmative); COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes YP_002563693.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.157(Affirmative); COG1520 Uncharacterized proteins of WD40-like repeat family YP_002563694.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002563695.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002563696.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002563697.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002563698.1 psort: bacterial cytoplasm --- Certainty= 0.177(Affirmative); COG0756 Dut dUTPase YP_002563699.1 psort: bacterial periplasmic space --- Certainty= 0.644(Affirmative); COG0770 MurF UDP-N-acetylmuramyl pentapeptide synthase YP_002563700.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.378(Affirmative) YP_002563701.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); psort: bacterial inner membrane --- Certainty= 0.722(Affirmative); COG3704 Type IV secretory pathway, VirB6 components YP_002563702.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); bacterial inner membrane --- Certainty= 0.836(Affirmative) bacterial outer membrane --- Certainty= 0.790(Affirmative); COG3704 Type IV secretory pathway, VirB6 components YP_002563703.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Possible type IV secretion system protein (virB6); psort: bacterial inner membrane --- Certainty= 0.675(Affirmative); COG3704 Type IV secretory pathway, VirB6 components YP_002563704.1 psort: bacterial inner membrane --- Certainty= 0.626(Affirmative); COG3704 VirB6 type IV secretory pathway, VirB6 components YP_002563705.1 psort: bacterial membrane --- Certainty= 0.588(Affirmative); COG3451 VirB4 type IV secretory pathway, VirB4 components YP_002563706.1 psort: bacterial inner membrane --- Certainty= 0.213(Affirmative); COG3702 VirB3 type IV secretory pathway, VirB3 components YP_002563707.1 psort: bacterial inner membrane --- Certainty= 0.128(Affirmative); COG0605 SodA superoxide dismutase YP_002563708.1 psort: bacterial inner membrane --- Certainty= 0.660(Affirmative); COG0581 PstA ABC-type phosphate transport system, permease component YP_002563710.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002563711.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.109(Affirmative) YP_002563712.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.584(Affirmative) YP_002563713.1 psort: bacterial membrane --- Certainty= 0.771(Affirmative); COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit YP_002563714.1 Synonym: sfhB; psort: bacterial cytoplasm --- Certainty= 0.134(Affirmative); COG0564 RluA pseudouridylate synthases, 23S RNA-specific YP_002563715.1 required for 70S ribosome assembly YP_002563716.1 psort: bacterial inner membrane --- Certainty= 0.304(Affirmative); COG1198 PriA primosomal protein N' (replication factor Y) - superfamily II helicase YP_002563717.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.155(Affirmative) YP_002563718.1 psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG1587 HemD Uroporphyrinogen-III synthase YP_002563719.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.145(Affirmative); COG0006 Xaa-Pro aminopeptidase YP_002563720.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.846(Affirmative); COG3577 Predicted aspartyl protease YP_002563721.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.037(Affirmative); COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB YP_002563722.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002563723.1 psort: bacterial cytoplasm --- Certainty= 0.243(Affirmative); COG0541 Ffh signal recognition particle GTPase YP_002563724.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_002563725.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outside --- Certainty= 0.300(Affirmative); COG2867 Oligoketide cyclase/lipid transport protein YP_002563726.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002563727.1 psort: bacterial cytoplasm --- Certainty= 0.143(Affirmative); COG1530 CafA ribonucleases G and E YP_002563728.1 called by Glimmer 2; subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002563729.1 called by Glimmer 2; subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002563730.1 called by Glimmer 2; subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002563731.1 called by Glimmer 2; subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002563732.1 called by Glimmer 2; subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_002563733.1 psort: bacterial cytoplasm --- Certainty= 0.161(Affirmative) YP_002563734.1 psort: bacterial inner membrane --- Certainty= 0.147(Affirmative); COH2317 Zn-dependent carboxypeptidases YP_002563735.1 psort: bacterial inner membrane --- Certainty= 0.291(Affirmative); COG2885 OmpA outer membrane protein and related peptidoglycan-associated (lipo)proteins YP_002563736.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002563737.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002563738.1 psort: bacterial cytoplasm --- Certainty= 0.129(Affirmative); COG1494 GlpX Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins YP_002563739.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002563740.1 psort: bacterial inner membrane --- Certainty= 0.126(Affirmative); COG0142 IspA geranylgeranyl pyrophosphate synthase YP_002563741.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative) YP_002563742.1 psort: bacterial periplasmic space --- Certainty= 0.711(Affirmative); COG0665 DadA Glycine/D-amino acid oxidases (deaminating) YP_002563743.1 unwinds double stranded DNA YP_002563744.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.236(Affirmative) YP_002563745.1 psort: bacterial cytoplasm --- Certainty= 0.064(Affirmative); COG0402 SsnA cytosine deaminase and related metal-dependent hydrolases YP_002563746.1 psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0332 FabH 3-oxoacyl-ACP synthase III YP_002563747.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002563748.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002563749.1 psort: bacterial cytoplasm --- Certainty= 0.172(Affirmative); COG0343 Tgt queuine/archaeosine tRNA-ribosyltransferase YP_002563750.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002563751.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002563752.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.131(Affirmative); COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_002563753.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_002563754.1 psort: bacterial cytoplasm --- Certainty= 0.255(Affirmative) YP_002563755.1 psort: bacterial cytoplasm --- Certainty= 0.077(Affirmative) YP_002563756.1 psort: bacterial inner membrane --- Certainty= 0.230(Affirmative) YP_002563757.1 psort: bacterial cytoplasm --- Certainty= 0.255(Affirmative) YP_002563758.1 psort: bacterial cytoplasm --- Certainty= 0.340(Affirmative) YP_002563759.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002563760.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.186(Affirmative) YP_002563761.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.561(Affirmative); COG1115 Na+/alanine symporter YP_002563762.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.535(Affirmative); COG0658 Predicted multitransmembrane, metal-binding protein YP_002563763.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002563764.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002563765.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002563766.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002563767.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002563768.1 psort: bacterial inner membrane --- Certainty= 0.208(Affirmative); COG0563 Adk adenylate kinase and related kinases YP_002563769.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002563770.1 late assembly protein YP_002563771.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002563772.1 binds 5S rRNA along with protein L5 and L25 YP_002563773.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002563774.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002563775.1 psort: bacterial cytoplasm --- Certainty= 0.248(Affirmative); COG0199 RpsN ribosomal protein S14 YP_002563776.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002563777.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002563778.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002563779.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002563780.1 one of the stabilizing components for the large ribosomal subunit YP_002563781.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002563782.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002563783.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002563784.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002563785.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002563786.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002563787.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002563788.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002563789.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002563790.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002563791.1 psort: bacterial cytoplasm --- Certainty= 0.108(Affirmative); COG0566 SpoU rRNA methylases YP_002563792.1 psort: bacterial cytoplasm --- Certainty= 0.151(Affirmative); COG0283 Cmk cytidylate kinase YP_002563793.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002563794.1 psort: bacterial inner membrane --- Certainty= 0.446(Affirmative); COG0616 SppA periplasmic serine proteases (ClpP class) YP_002563795.1 Hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.655(Affirmative) YP_002563796.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.292(Affirmative) YP_002563797.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.435(Affirmative) YP_002563798.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002563799.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG1485 Predicted ATPase YP_002563800.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.216(Affirmative) YP_002563801.1 psort: bacterial inner membrane --- Certainty= 0.397(Affirmative); COG0330 HflC membrane protease subunits, stomatin/prohibitin homologs YP_002563802.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.128(Affirmative) YP_002563803.1 psort: bacterial cytoplasm --- Certainty= 0.239(Affirmative); COG1074 RecB ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) YP_002563804.1 psort: bacterial cytoplasm --- Certainty= 0.371(Affirmative); COG0604 Qor NADPH:quinone reductase and related Zn-dependent oxidoreductases YP_002563805.1 psort: bacterial inner membrane --- Certainty= 0.478(Affirmative); COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component YP_002563806.1 psort: bacterial cytoplasm --- Certainty= 0.270(Affirmative); COG0294 FolP dihydropteroate synthase and related enzymes YP_002563807.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002563808.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.355(Affirmative) YP_002563809.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002563810.1 psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0452 Dfp Phosphopantothenoylcysteine synthetase/decarboxylase YP_002563811.1 psort: bacterial cytoplasm --- Certainty= 0.356(Affirmative); dihydroorotase and related cyclic amidohydrolases YP_002563812.1 psort: bacterial inner membrane --- Certainty= 0.200(Affirmative); COG1109 CpsG phosphomannomutase YP_002563813.1 psort: bacterial cytoplasm --- Certainty= 0.232(Affirmative); COG0321 LipB lipoate-protein ligase B YP_002563814.1 psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG2003 RadC DNA repair proteins YP_002563815.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002563816.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002563817.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.187(Affirmative); COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_002563818.1 psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0542 ATPases with chaperone activity, ATP-binding subunit YP_002563819.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.586(Affirmative) YP_002563820.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.480(Affirmative) YP_002563821.1 psort: bacterial outer membrane --- Certainty= 0.935(Affirmative); COG3485 PcaH Protocatechuate 3,4-dioxygenase beta subunit YP_002563822.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.307(Affirmative) YP_002563823.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002563824.1 psort: bacterial inner membrane --- Certainty= 0.104(Affirmative); COG0299 PurN Folate-dependent phosphoribosylglycinamide formyltransferase PurN YP_002563825.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_505, AMF_509, AMF_571, and AMF_790 .; psort: bacterial inner membrane --- Certainty= 0.544(Affirmative) YP_002563826.1 psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain YP_002563827.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002563828.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_002563829.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative); COG0739 Membrane proteins related to metalloendopeptidases YP_002563830.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.187(Affirmative) YP_002563831.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.183(Affirmative) YP_002563832.1 psort: bacterial cytoplasm --- Certainty= 0.209(Affirmative); COG0502 BioB biotin synthase and related enzymes YP_002563833.1 psort: bacterial inner membrane --- Certainty= 0.215(Affirmative); COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain YP_002563834.1 psort: bacterial cytoplasm --- Certainty= 0.253(Affirmative); COG0294 FolP Dihydropteroate synthase and related enzymes YP_002563835.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.247(Affirmative) YP_002563836.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.193(Affirmative); COG0501 Zn-dependent protease with chaperone function YP_002563837.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.176(Affirmative); COG0799 Uncharacterized ACR (homolog of plant Iojap proteins) YP_002563838.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.334(Affirmative) YP_002563839.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.198(Affirmative) YP_002563840.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002563841.1 psort: bacterial cytoplasm --- Certainty= 0.189(Affirmative); COG0582 XerC integrase YP_002563842.1 psort: bacterial inner membrane --- Certainty= 0.191(Affirmative); COG0240 GpsA glycerol 3-phosphate dehydrogenase YP_002563843.1 Member of the msp2 superfamily; Truncated compared to St. Maries; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative) YP_002563844.1 Member of the msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563845.1 Member of the msp2 superfamily; psort: bacterial periplasmic space --- Certainty= 0.902(Affirmative) YP_002563846.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002563847.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.266(Affirmative) YP_002563848.1 heat shock protein involved in degradation of misfolded proteins YP_002563849.1 heat shock protein involved in degradation of misfolded proteins YP_002563850.1 psort: bacterial cytoplasm --- Certainty= 0.266(Affirmative); COG2226 UbiE methylase involved in ubiquinone/menaquinone biosynthesis YP_002563851.1 psort: bacterial inner membrane --- Certainty= 0.253(Affirmative); COG0143 MetG methionyl-tRNA synthetase YP_002563852.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_002563853.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative) YP_002563854.1 psort: bacterial inner membrane --- Certainty= 0.548(Affirmative); COG1622 CyoA Heme/copper-type cytochrome/quinol oxidases, subunit 2 YP_002563855.1 psort: bacterial inner membrane --- Certainty= 0.448(Affirmative); COG0843 CyoB Heme/copper-type cytochrome/quinol oxidases, subunit 1 YP_002563856.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002563857.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.922(Affirmative); COG0457 TPR-repeat-containing proteins YP_002563858.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002563859.1 psort: bacterial inner membrane --- Certainty= 0.522(Affirmative); COG1862 YajC preprotein translocase subunit YajC YP_002563860.1 psort: bacterial inner membrane --- Certainty= 0.200(Affirmative); COG0449 GlmS glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains YP_002563861.1 psort: bacterial cytoplasm --- Certainty= 0.192(Affirmative); COG0592 DnaN DNA polymerase sliding clamp subunit (PCNA homolog) YP_002563862.1 other copies include: AM151; psort: bacterial cytoplasm --- Certainty= 0.224(Affirmative); COG0349 Rnd ribonuclease D YP_002563863.1 psort: bacterial inner membrane --- Certainty= 0.143(Affirmative); COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_002563864.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.151(Affirmative); COG2932 Predicted transcriptional regulator YP_002563865.1 psort: bacterial inner membrane --- Certainty= 0.240(Affirmative); COG0221 Ppa inorganic pyrophosphatase YP_002563866.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.235(Affirmative) YP_002563867.1 forms a direct contact with the tRNA during translation YP_002563868.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002563869.1 psort: bacterial inner membrane --- Certainty= 0.295(Affirmative); COG1538 TolC outer membrane protein YP_002563870.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.164(Affirmative) YP_002563871.1 psort: bacterial cytoplasm --- Certainty= 0.248(Affirmative); COG0489 Mrp ATPases involved in chromosome partitioning YP_002563872.1 psort: bacterial periplasmic space --- Certainty= 0.933(Affirmative); COG0462 PrsA phosphoribosylpyrophosphate synthetase YP_002563873.1 psort: bacterial cytoplasm --- Certainty= 0.174(Affirmative) YP_002563874.1 Catalyzes the conversion of citrate to isocitrate YP_002563875.1 protein associated with Co2+ and Mg2+ efflux YP_002563876.1 psort: bacterial inner membrane --- Certainty= 0.342(Affirmative); COG0026 PurK phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) YP_002563877.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.938(Affirmative) YP_002563878.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_505, AMF_509, AMF_571, and AMF_735 .; psort: bacterial inner membrane --- Certainty= 0.480(Affirmative) YP_002563879.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.312(Affirmative) YP_002563880.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Significant similarity to AMF_794 psort: bacterial inner membrane --- Certainty= 0.423(Affirmative) YP_002563881.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Significant similarity to AMF_794 psort: bacterial inner membrane --- Certainty= 0.539(Affirmative) YP_002563882.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.172(Affirmative) YP_002563883.1 psort: bacterial cytoplasm --- Certainty= 0.571(Affirmative); COG3451 VirB4 type IV secretory pathway, VirB4 components YP_002563884.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Significant similarity to AMF_798, AMF_154, AMF_755, AMF_801, AMF_59, AMF_870, AMF_33, AMF_23, AMF_49, AMF_947, AMF_57, AMF_532, AMF_536, AMF_799, AMF_873, AMF_756, AMF_24, AMF_946, AMF_800, AMF_535, and AMF_48.; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563885.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Significant similarity to AMF_797, AMF_154, AMF_755, AMF_801, AMF_59, AMF_870, AMF_33, AMF_23, AMF_49, AMF_947, AMF_57, AMF_532, AMF_536, AMF_799, AMF_873, AMF_756, AMF_24, AMF_946, AMF_800, AMF_535, and AMF_48.; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563886.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Contains the ORF X internal motif; psort: bacterial inner membrane --- Certainty= 0.408(Affirmative) YP_002563887.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.210(Affirmative) YP_002563888.1 psort: bacterial inner membrane --- Certainty= 0.213(Affirmative) YP_002563889.1 psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563890.1 member of msp2 superfamily; psort: bacterial periplasmic space --- Certainty= 0.930(Affirmative) YP_002563891.1 psort: bacterial inner membrane --- Certainty= 0.289(Affirmative); COG0330 HflC membrane protease subunits, stomatin/prohibitin homologs YP_002563892.1 psort: bacterial inner membrane --- Certainty= 0.355(Affirmative); COG0330 HflC membrane protease subunits, stomatin/prohibitin homologs YP_002563893.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.846(Affirmative); COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_002563894.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.526(Affirmative) YP_002563895.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002563896.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_002563897.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.431(Affirmative) YP_002563898.1 psort: bacterial inner membrane --- Certainty= 0.618(Affirmative) YP_002563899.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.002(Affirmative) YP_002563900.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.548(Affirmative) YP_002563901.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.259(Affirmative); COG0612 Predicted Zn-dependent peptidases YP_002563902.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.100(Affirmative); COG0612 Predicted Zn-dependent peptidases YP_002563903.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002563904.1 psort: bacterial cytoplasm --- Certainty= 0.105(Affirmative); COG0196 RibF FAD synthase YP_002563905.1 psort: bacterial cytoplasm --- Certainty= 0.319(Affirmative); COG0695 GrxC glutaredoxin and related proteins YP_002563906.1 psort: bacterial inner membrane --- Certainty= 0.123(Affirmative); COG2890 HemK predicted rRNA or tRNA methylase YP_002563907.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002563908.1 psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0508 AceF dihydrolipoamide acyltransferases YP_002563909.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.030(Affirmative); COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily YP_002563910.1 psort: bacterial cytoplasm --- Certainty= 0.232(Affirmative); COG0414 PanC pantothenate synthetase YP_002563911.1 psort: bacterial periplasmic space --- Certainty= 0.623(Affirmative); COG1686 DacC D-alanyl-D-alanine carboxypeptidase YP_002563912.1 psort: bacterial inner membrane --- Certainty= 0.427(Affirmative); COG0526 TrxA thiol-disulfide isomerase and thioredoxins YP_002563913.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.337(Affirmative); COG2938 Uncharacterized ACR YP_002563914.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.525(Affirmative); COG0750 Predicted membrane-associated Zn-dependent proteases 1 YP_002563915.1 psort: bacterial outer membrane --- Certainty= 0.936(Affirmative); COG4775 - outer membrane protein/protective antigen OMA87 YP_002563916.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.944(Affirmative) YP_002563917.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002563918.1 psort: bacterial inner membrane --- Certainty= 0.162(Affirmative); COG0138 PurH AICAR transformylase/IMP cyclohydrolase PurH YP_002563919.1 psort: bacterial inner membrane --- Certainty= 0.359(Affirmative); COG0558 PgsA phosphatidylglycerophosphate synthase YP_002563920.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.592(Affirmative); COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 YP_002563921.1 psort: bacterial inner membrane --- Certainty= 0.293(Affirmative); COG0741 MltE soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) YP_002563922.1 psort: bacterial inner membrane --- Certainty= 0.501(Affirmative); COG3346 - uncharacterized conserved protein YP_002563923.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.917(Affirmative); COG1357 Unchacterized low-complexity proteins YP_002563924.1 psort: bacterial inner membrane --- Certainty= 0.359(Affirmative); COG0371 GldA glycerol dehydrogenase and related enzymes YP_002563925.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002563926.1 Hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.917(Affirmative) YP_002563927.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002563928.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.191(Affirmative) YP_002563929.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.917(Affirmative) YP_002563930.1 psort: bacterial inner membrane --- Certainty= 0.134(Affirmative); COG0849 FtsA predicted ATPases of the HSP70 class involved in cell division YP_002563931.1 psort: bacterial inner membrane --- Certainty= 0.639(Affirmative); COG0168 TrkG Trk-type K+ transport systems, membrane components YP_002563932.1 psort: bacterial cytoplasm --- Certainty= 0.138(Affirmative); COG0037 MesJ predicted ATPase of the PP-loop superfamily implicated in cell cycle control YP_002563933.1 psort: bacterial inner membrane --- Certainty= 0.457(Affirmative); COG0465 HflB ATP-dependent Zn proteases YP_002563934.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002563935.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.160(Affirmative) YP_002563936.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative) YP_002563937.1 psort: bacterial inner membrane --- Certainty= 0.482(Affirmative); COG1230 CzcD Co/Zn/Cd efflux system component YP_002563938.1 psort: bacterial inner membrane --- Certainty= 0.686(Affirmative); COG2386 CcmB ABC-type transport system involved in cytochrome c biogenesis, permease component YP_002563939.1 psort: bacterial cytoplasm --- Certainty= 0.549(Affirmative); COG1734 DksA DnaK suppressor protein YP_002563940.1 psort: bacterial inner membrane --- Certainty= 0.177(Affirmative); COG0132 BioD dethiobiotin synthetase YP_002563941.1 psort: bacterial cytoplasm --- Certainty= 0.333(Affirmative); COG0552 FtsY signal recognition particle GTPase YP_002563942.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_002563943.1 psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0608 RecJ single-stranded DNA-specific exonuclease YP_002563944.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.134(Affirmative) YP_002563945.1 psort: bacterial cytoplasm --- Certainty= 0.092(Affirmative; COG0617 PcnB tRNA nucleotidyltransferase/poly(A) polymerase YP_002563946.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002563947.1 psort: bacterial cytoplasm --- Certainty= 0.191(Affirmative); COG1396 Predicted transcriptional regulators YP_002563948.1 Member of msp2 superfamily; Also known as Ana37; psort: bacterial periplasmic space --- Certainty= 0.861(Affirmative) YP_002563949.1 Member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.264(Affirmative) YP_002563950.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.548(Affirmative) YP_002563951.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.921(Affirmative) YP_002563952.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.934(Affirmative) YP_002563953.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.582(Affirmative) YP_002563954.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.318(Affirmative); COG0694 Thioredoxin-like proteins and domains YP_002563955.1 Member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002563956.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; Contains the ORF X internal motif; psort: bacterial periplasmic space --- Certainty= 0.915(Affirmative) YP_002563957.1 Member of msp2 superfamily; psort: bacterial cytoplasm --- Certainty= 0.481(Affirmative) YP_002563958.1 Member of msp2 superfamily; Significant sequence similarity to AMF_56 (highest in C-terminal end); psort: bacterial cytoplasm --- Certainty= 0.225(Affirmative) YP_002563959.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.191(Affirmative) YP_002563960.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.790(Affirmative) YP_002563961.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.206(Affirmative) YP_002563962.1 Member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.401(Affirmative) YP_002563963.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.318(Affirmative); COG0354 Predicted aminomethyltransferase related to GcvT YP_002563964.1 psort: bacterial inner membrane --- Certainty= 0.529(Affirmative); COG1138 CcmF cytochrome c biogenesis factor YP_002563965.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002563966.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002563967.1 psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0807 RibA GTP cyclohydrolase II YP_002563968.1 psort: bacterial cytoplasm --- Certainty= 0.417(Affirmative); COG0782 GreA transcription elongation factor YP_002563969.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002563970.1 psort: bacterial inner membrane --- Certainty= 0.123(Affirmative); COG0712 AtpH F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein) YP_002563971.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.401(Affirmative) YP_002563972.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.609(Affirmative) YP_002563973.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.930(Affirmative) YP_002563974.1 psort: bacterial inner membrane --- Certainty= 0.605(Affirmative) YP_002563975.1 psort: bacterial cytoplasm --- Certainty= 0.398(Affirmative); COG1466 HolA DNA polymerase III delta subunit YP_002563976.1 psort: bacterial cytoplasm --- Certainty= 0.336(Affirmative); COG2918 GshA Gamma-glutamylcysteine synthetase YP_002563977.1 psort: bacterial cytoplasm --- Certainty= 0.043(Affirmative); COG0372 GltA citrate synthase YP_002563978.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002563979.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.169(Affirmative) YP_002563980.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.362(Affirmative) YP_002563981.1 psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0508 AceF dihydrolipoamide acyltransferases YP_002563982.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_002563983.1 psort: bacterial inner membrane --- Certainty= 0.348(Affirmative); COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2 YP_002563984.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002563985.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.061(Affirmative); COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase YP_002563986.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_002563987.1 psort: bacterial cytoplasm --- Certainty= 0.176(Affirmative); COG0162 TyrS tyrosyl-tRNA synthetase YP_002563988.1 psort: bacterial inner membrane --- Certainty= 0.251(Affirmative); COG0174 GlnA glutamine synthase YP_002563989.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002563990.1 psort: bacterial inner membrane --- Certainty= 0.181(Affirmative); COG0142 IspA geranylgeranyl pyrophosphate synthase YP_002563991.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.310(Affirmative) YP_002563992.1 psort: bacterial cytoplasm --- Certainty= 0.267(Affirmative); COG1127 Ttg2A ABC-type exporter of toluene and related compounds, ATPase component YP_002563993.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.365(Affirmative); COG0767 ABC-type toluene export system, permease component YP_002563994.1 psort: bacterial inner membrane --- Certainty= 0.126(Affirmative); COG0036 Rpe pentose-5-phosphate-3-epimerase YP_002563995.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002563996.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.711(Affirmative) YP_002563997.1 psort: bacterial cytoplasm --- Certainty= 0.023(Affirmative); COG0078 ArgF ornithine carbamoyltransferase YP_002563998.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_002563999.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.794(Affirmative) YP_002564000.1 Member of msp2 superfamily; psort: bacterial periplasmic space --- Certainty= 0.508(Affirmative) YP_002564001.1 Member of msp2 superfamily; psort: bacterial periplasmic space --- Certainty= 0.356(Affirmative) YP_002564002.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.444(Affirmative) YP_002564003.1 Member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.281(Affirmative) YP_002564004.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.081(Affirmative) YP_002564005.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.353(Affirmative) YP_002564006.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.007(Affirmative) YP_002564007.1 psort: bacterial inner membrane --- Certainty= 0.629(Affirmative); COG0728 MviN uncharacterized membrane protein, virulence factor YP_002564008.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002564009.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.023(Affirmative) YP_002564010.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002564011.1 psort: bacterial inner membrane --- Certainty= 0.385(Affirmative); COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002564012.1 psort: bacterial cytoplasm --- Certainty= 0.195(Affirmative); COG0242 Def N-formylmethionyl-tRNA deformylase YP_002564013.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.312(Affirmative); COG1573 Uracil-DNA glycosylase YP_002564014.1 Hypothetical protein called by Glimmer 2; psort: bacterial outer membrane --- Certainty= 0.915(Affirmative) YP_002564015.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.257(Affirmative) YP_002564016.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.286(Affirmative) YP_002564017.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_940 psort: bacterial cytoplasm --- Certainty= 0.394(Affirmative) YP_002564018.1 Hypothetical protein called by Glimmer 2; Significant similarity to AMF_939 psort: bacterial cytoplasm --- Certainty= 0.115(Affirmative) YP_002564019.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002564020.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002564021.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.542(Affirmative) YP_002564022.1 Member of msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.676(Affirmative) YP_002564023.1 Member of msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.414(Affirmative) YP_002564024.1 psort: bacterial inner membrane --- Certainty= 0.106(Affirmative); COG0043 UbiD 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases YP_002564025.1 Member of the msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.785(Affirmative) YP_002564026.1 Member of the msp2 superfamily; psort: bacterial outer membrane --- Certainty= 0.940(Affirmative) YP_002564027.1 Member of the msp2 superfamily; psort: bacterial inner membrane --- Certainty= 0.353(Affirmative) YP_002564028.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002564029.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.427(Affirmative); COG0319 Predicted metal-dependent hydrolase YP_002564030.1 psort: bacterial cytoplasm --- Certainty= 0.252(Affirmative); COG1192 Soj ATPases involved in chromosome partitioning YP_002564031.1 psort: bacterial cytoplasm --- Certainty= 0.231(Affirmative); COG1475 Spo0J predicted transcriptional regulators YP_002564032.1 Essential for efficient processing of 16S rRNA YP_002564033.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002564034.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002564035.1 psort: bacterial inner membrane --- Certainty= 0.304(Affirmative); COG1058 CinA predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA YP_002564036.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002564037.1 psort: bacterial cytoplasm --- Certainty= 0.223(Affirmative); COG0290 InfC translation initiation factor IF3 YP_002564038.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.153(Affirmative); COG0802 Predicted ATPase or kinase YP_002564039.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.459(Affirmative); COG0670 Integral membrane protein, interacts with FtsH YP_002564040.1 psort: bacterial cytoplasm --- Certainty= 0.076(Affirmative); COG0136 Asd aspartate-semialdehyde dehydrogenase YP_002564041.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.515(Affirmative) YP_002564042.1 psort: bacterial inner membrane --- Certainty= 0.138(Affirmative); COG2812 DnaX DNA polymerase III, gamma/tau subunits YP_002564043.1 psort: bacterial cytoplasm --- Certainty= 0.128(Affirmative); COG0057 GapA glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase YP_002564044.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.448(Affirmative) YP_002564045.1 psort: bacterial inner membrane --- Certainty= 0.289(Affirmative); COG3155 ElbB Uncharacterized sigma cross-reacting protein 27A (ES1 or KNP-I alpha protein) YP_002564046.1 psort: bacterial inner membrane --- Certainty= 0.595(Affirmative); COG0772 FtsW bacterial cell division membrane protein YP_002564047.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002564048.1 psort: bacterial inner membrane --- Certainty= 0.238(Affirmative); COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_002564049.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.654(Affirmative) YP_002564050.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002564051.1 psort: bacterial inner membrane --- Certainty= 0.179(Affirmative); COG0751 GlyS glycyl-tRNA synthetase, beta subunit YP_002564052.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002564053.1 psort: bacterial cytoplasm --- Certainty= 0.379(Affirmative); COG0157 NadC nicotinate-nucleotide pyrophosphorylase YP_002564054.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.533(Affirmative); COG0344 Predicted membrane protein YP_002564055.1 psort: bacterial cytoplasm --- Certainty= 0.172(Affirmative); COG0817 RuvC holliday junction resolvasome endonuclease subunit YP_002564056.1 psort: bacterial inner membrane --- Certainty= 0.370(Affirmative); COG1845 CyoC heme/copper-type cytochrome/quinol oxidase, subunit 3 YP_002564057.1 psort: bacterial inner membrane --- Certainty= 0.225(Affirmative); COG0407 HemE uroporphyrinogen-III decarboxylase YP_002564058.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.230(Affirmative); COG1253 Hemolysins and related proteins containing CBS domains YP_002564059.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.213(Affirmative); COG3740 - phage head maturation protease YP_002564060.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.054(Affirmative) YP_002564061.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.168(Affirmative); COG0500 SAM-dependent methyltransferases YP_002564062.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002564063.1 psort: bacterial cytoplasm --- Certainty= 0.270(Affirmative); COG1145 NapF ferredoxin 2 YP_002564064.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002564065.1 psort: bacterial cytoplasm --- Certainty= 0.514(Affirmative); COG0290 InfC translation initiation factor IF3 YP_002564066.1 psort: bacterial inner membrane --- Certainty= 0.355(Affirmative); COG3505 VirD4 type IV secretory pathway, VirD4 components YP_002564067.1 psort: bacterial cytoplasm --- Certainty= 0.168(Affirmative); COG0630 VirB11 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis YP_002564068.1 psort: bacterial inner membrane --- Certainty= 0.334(Affirmative); COG2948 VirB10 type IV secretory pathway, VirB10 components YP_002564069.1 psort: bacterial periplasmic space --- Certainty= 0.742(Affirmative); COG3504 VirB9 type IV secretory pathway, VirB9 components YP_002564070.1 psort: bacterial inner membrane --- Certainty= 0.576(Affirmative); COG3736 VirB8 type IV secretion system, component VirB8 YP_002564071.1 psort: bacterial cytoplasm --- Certainty= 0.289(Affirmative); COG0807 RibA GTP cyclohydrolase II YP_002564072.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.438(Affirmative) YP_002564073.1 Hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.408(Affirmative) YP_002564074.1 psort: bacterial cytoplasm --- Certainty= 0.142(Affirmative); COG0253 DapF diaminopimelate epimerase YP_002564075.1 Hypothetical protein called by Glimmer 2; psort: bacterial periplasmic space --- Certainty= 0.932(Affirmative) YP_002564076.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.391(Affirmative) YP_002564077.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002564078.1 psort: bacterial cytoplasm --- Certainty= 0.273(Affirmative); COG1570 XseA exonuclease VII, large subunit YP_002564079.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.346(Affirmative) YP_002564080.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002564081.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002564082.1 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. YP_002564083.1 psort: bacterial inner membrane --- Certainty= 0.111(Affirmative); COG1200 RecG RecG-like helicases YP_002564084.1 psort: bacterial inner membrane --- Certainty= 0.102(Affirmative); COG0702 Predicted nucleoside-diphosphate-sugar epimerases YP_002564085.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002564086.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002564087.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002564088.1 psort: bacterial inner membrane --- Certainty= 0.185(Affirmative); COG1040 ComFC Predicted amidophosphoribosyltransferases YP_002564089.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002564090.1 psort: bacterial inner membrane --- Certainty= 0.637(Affirmative); COG0475 KefB Kef-type K+ transport systems, membrane components YP_002564091.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.340(Affirmative); COG0526 Thiol-disulfide isomerase and thioredoxins YP_002564092.1 called by Glimmer 2; Conserved hypothetical protein called by Glimmer 2; psort: bacterial inner membrane --- Certainty= 0.401(Affirmative); COG1981 Predicted membrane protein YP_002564093.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase YP_002564094.1 Hypothetical protein called by Glimmer 2; psort: bacterial cytoplasm --- Certainty= 0.285(Affirmative) YP_002564095.1 psort: bacterial cytoplasm --- Certainty= 0.333(Affirmative); COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs YP_002564096.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002564097.1 psort: bacterial cytoplasm --- Certainty= 0.051(Affirmative); COG0245 IspF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002564098.1 psort: bacterial periplasmic space --- Certainty= 0.786(Affirmative); COG1211 IspD 4-diphosphocytidyl-2-methyl-D-erithritol synthase