-- dump date 20120504_134637 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_031731.1 49473689 2867435 1..843 1 NC_005955.1 hypothetical protein 843 2867435 BQ00010 Bartonella quintana str. Toulouse hypothetical protein YP_031731.1 1 D 283165 CDS YP_031732.1 49473690 2866470 840..1436 1 NC_005955.1 septum formation maf protein 1436 maf-1 2866470 maf-1 Bartonella quintana str. Toulouse septum formation maf protein YP_031732.1 840 D 283165 CDS YP_031733.1 49473691 2867106 1429..2310 1 NC_005955.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 2310 aroE 2867106 aroE Bartonella quintana str. Toulouse shikimate 5-dehydrogenase YP_031733.1 1429 D 283165 CDS YP_031734.1 49473692 2867020 2307..2894 1 NC_005955.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2894 coaE 2867020 coaE Bartonella quintana str. Toulouse dephospho-CoA kinase YP_031734.1 2307 D 283165 CDS YP_031735.1 49473693 2866681 2899..3606 1 NC_005955.1 DNA polymerase III epsilon chain 3606 dnaQ 2866681 dnaQ Bartonella quintana str. Toulouse DNA polymerase III epsilon chain YP_031735.1 2899 D 283165 CDS YP_031736.1 49473694 2866878 3938..6844 1 NC_005955.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 6844 polA 2866878 polA Bartonella quintana str. Toulouse DNA polymerase I YP_031736.1 3938 D 283165 CDS YP_031737.1 49473695 2866348 complement(6851..7738) 1 NC_005955.1 hypothetical protein 7738 2866348 BQ00070 Bartonella quintana str. Toulouse hypothetical protein YP_031737.1 6851 R 283165 CDS YP_031738.1 49473696 2867415 complement(7829..8602) 1 NC_005955.1 hypothetical protein 8602 2867415 BQ00080 Bartonella quintana str. Toulouse hypothetical protein YP_031738.1 7829 R 283165 CDS YP_031739.1 49473697 2867202 complement(9856..10359) 1 NC_005955.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 10359 lspA 2867202 lspA Bartonella quintana str. Toulouse lipoprotein signal peptidase YP_031739.1 9856 R 283165 CDS YP_031740.1 49473698 2866938 complement(10385..11221) 1 NC_005955.1 tRNA/rRNA methyltransferase 11221 2866938 BQ00100 Bartonella quintana str. Toulouse tRNA/rRNA methyltransferase YP_031740.1 10385 R 283165 CDS YP_031741.1 49473699 2867244 complement(12328..12597) 1 NC_005955.1 hypothetical protein 12597 2867244 BQ00120 Bartonella quintana str. Toulouse hypothetical protein YP_031741.1 12328 R 283165 CDS YP_031742.1 49473700 2866667 complement(12606..12884) 1 NC_005955.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 12884 ihfB 2866667 ihfB Bartonella quintana str. Toulouse integration host factor subunit beta YP_031742.1 12606 R 283165 CDS YP_031743.1 49473701 2867246 13076..13744 1 NC_005955.1 hypothetical protein 13744 2867246 BQ00140 Bartonella quintana str. Toulouse hypothetical protein YP_031743.1 13076 D 283165 CDS YP_031744.1 49473702 2867524 13858..14436 1 NC_005955.1 hypothetical protein 14436 2867524 BQ00150 Bartonella quintana str. Toulouse hypothetical protein YP_031744.1 13858 D 283165 CDS YP_031745.1 49473703 2866865 14443..15237 1 NC_005955.1 ABC transporter/ATP-binding protein 15237 2866865 BQ00160 Bartonella quintana str. Toulouse ABC transporter/ATP-binding protein YP_031745.1 14443 D 283165 CDS YP_031746.1 49473704 2867270 16415..16879 1 NC_005955.1 nitrogen regulatory IIA 16879 ptsN 2867270 ptsN Bartonella quintana str. Toulouse nitrogen regulatory IIA YP_031746.1 16415 D 283165 CDS YP_031747.1 49473705 2867038 18280..18789 1 NC_005955.1 hypothetical protein 18789 2867038 BQ00180 Bartonella quintana str. Toulouse hypothetical protein YP_031747.1 18280 D 283165 CDS YP_031748.1 49473706 2867481 18831..20060 1 NC_005955.1 hypothetical protein 20060 2867481 BQ00190 Bartonella quintana str. Toulouse hypothetical protein YP_031748.1 18831 D 283165 CDS YP_031749.1 49473707 2867222 21803..23464 1 NC_005955.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 23464 lysK 2867222 lysK Bartonella quintana str. Toulouse lysyl-tRNA synthetase YP_031749.1 21803 D 283165 CDS YP_031750.1 49473708 2867049 23464..25041 1 NC_005955.1 peptide chain release factor 3 25041 prfC 2867049 prfC Bartonella quintana str. Toulouse peptide chain release factor 3 YP_031750.1 23464 D 283165 CDS YP_031751.1 49473709 2866811 complement(25143..25466) 1 NC_005955.1 thioredoxin 25466 trxA 2866811 trxA Bartonella quintana str. Toulouse thioredoxin YP_031751.1 25143 R 283165 CDS YP_031752.1 49473710 2866756 complement(25577..29050) 1 NC_005955.1 ATP-dependent nuclease subunit A 29050 addA 2866756 addA Bartonella quintana str. Toulouse ATP-dependent nuclease subunit A YP_031752.1 25577 R 283165 CDS YP_031753.1 49473711 2867452 complement(29047..32166) 1 NC_005955.1 hypothetical protein 32166 2867452 BQ00260 Bartonella quintana str. Toulouse hypothetical protein YP_031753.1 29047 R 283165 CDS YP_031754.1 49473712 2866812 complement(33914..35416) 1 NC_005955.1 chlorosome protein 35416 2866812 BQ00270 Bartonella quintana str. Toulouse chlorosome protein YP_031754.1 33914 R 283165 CDS YP_031755.1 49473713 2867483 complement(35491..37935) 1 NC_005955.1 sensor histidine kinase 37935 2867483 BQ00280 Bartonella quintana str. Toulouse sensor histidine kinase YP_031755.1 35491 R 283165 CDS YP_031756.1 49473714 2866636 complement(37975..39372) 1 NC_005955.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 39372 ahcY 2866636 ahcY Bartonella quintana str. Toulouse S-adenosyl-L-homocysteine hydrolase YP_031756.1 37975 R 283165 CDS YP_031757.1 49473715 2867008 complement(40065..41069) 1 NC_005955.1 NADH-ubiquinone oxidoreductase 41069 2867008 BQ00300 Bartonella quintana str. Toulouse NADH-ubiquinone oxidoreductase YP_031757.1 40065 R 283165 CDS YP_031758.1 49473716 2867406 complement(41107..42426) 1 NC_005955.1 folylpolyglutamate synthase 42426 folC 2867406 folC Bartonella quintana str. Toulouse folylpolyglutamate synthase YP_031758.1 41107 R 283165 CDS YP_031759.1 49473717 2866376 complement(42430..43350) 1 NC_005955.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 43350 accD 2866376 accD Bartonella quintana str. Toulouse acetyl-CoA carboxylase subunit beta YP_031759.1 42430 R 283165 CDS YP_031760.1 49473718 2866410 complement(45452..46834) 1 NC_005955.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; in the alphaproteobacteria, this protein contains an N-terminal SbtC-like domain; bifunctional SbtC-like/phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 46834 dfp 2866410 dfp Bartonella quintana str. Toulouse bifunctional SbtC-like/phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_031760.1 45452 R 283165 CDS YP_031761.1 49473719 2866319 complement(46904..48490) 1 NC_005955.1 ubiquinone biosynthesis protein Aarf 48490 aarF 2866319 aarF Bartonella quintana str. Toulouse ubiquinone biosynthesis protein Aarf YP_031761.1 46904 R 283165 CDS YP_031762.1 49473720 2866639 complement(48493..49275) 1 NC_005955.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 49275 ubiE 2866639 ubiE Bartonella quintana str. Toulouse ubiquinone/menaquinone biosynthesis methyltransferase YP_031762.1 48493 R 283165 CDS YP_031763.1 49473721 2867167 complement(49393..51825) 1 NC_005955.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 51825 gyrB 2867167 gyrB Bartonella quintana str. Toulouse DNA gyrase subunit B YP_031763.1 49393 R 283165 CDS YP_031764.1 49473722 2866760 52812..53681 1 NC_005955.1 ABC transporter periplasmic amino acid-binding protein 53681 2866760 BQ00380 Bartonella quintana str. Toulouse ABC transporter periplasmic amino acid-binding protein YP_031764.1 52812 D 283165 CDS YP_031765.1 49473723 2866653 complement(53694..55226) 1 NC_005955.1 competence protein comM 55226 comM 2866653 comM Bartonella quintana str. Toulouse competence protein comM YP_031765.1 53694 R 283165 CDS YP_031766.1 49473724 2867505 55641..57602 1 NC_005955.1 hypothetical protein 57602 2867505 BQ00400 Bartonella quintana str. Toulouse hypothetical protein YP_031766.1 55641 D 283165 CDS YP_031767.1 49473725 2867498 57602..62248 1 NC_005955.1 hypothetical protein 62248 2867498 BQ00410 Bartonella quintana str. Toulouse hypothetical protein YP_031767.1 57602 D 283165 CDS YP_031768.1 49473726 2866485 complement(62277..64043) 1 NC_005955.1 ABC transporter ATP-binding protein 64043 msbA 2866485 msbA Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_031768.1 62277 R 283165 CDS YP_031769.1 49473727 2866385 complement(64266..64784) 1 NC_005955.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 64784 infC 2866385 infC Bartonella quintana str. Toulouse translation initiation factor IF-3 YP_031769.1 64266 R 283165 CDS YP_031770.1 49473728 2866505 64981..65778 1 NC_005955.1 hypothetical protein 65778 2866505 BQ00440 Bartonella quintana str. Toulouse hypothetical protein YP_031770.1 64981 D 283165 CDS YP_031771.1 49473729 2866608 65796..66542 1 NC_005955.1 hypothetical protein 66542 2866608 BQ00450 Bartonella quintana str. Toulouse hypothetical protein YP_031771.1 65796 D 283165 CDS YP_031772.1 49473730 2867597 66765..67937 1 NC_005955.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 67937 dapE 2867597 dapE Bartonella quintana str. Toulouse succinyl-diaminopimelate desuccinylase YP_031772.1 66765 D 283165 CDS YP_031773.1 49473731 2866422 complement(68037..69236) 1 NC_005955.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 69236 hemN 2866422 hemN Bartonella quintana str. Toulouse coproporphyrinogen III oxidase YP_031773.1 68037 R 283165 CDS YP_031774.1 49473732 2866883 complement(69233..69880) 1 NC_005955.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 69880 2866883 BQ00480 Bartonella quintana str. Toulouse deoxyribonucleotide triphosphate pyrophosphatase YP_031774.1 69233 R 283165 CDS YP_031775.1 49473733 2866523 70197..71267 1 NC_005955.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 71267 hrcA 2866523 hrcA Bartonella quintana str. Toulouse heat-inducible transcription repressor YP_031775.1 70197 D 283165 CDS YP_031776.1 49473734 2867394 71392..72054 1 NC_005955.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 72054 grpE 2867394 grpE Bartonella quintana str. Toulouse heat shock protein GrpE YP_031776.1 71392 D 283165 CDS YP_031777.1 49473735 2866482 complement(72169..72708) 1 NC_005955.1 ABC transporter (permease) 72708 2866482 BQ00510 Bartonella quintana str. Toulouse ABC transporter (permease) YP_031777.1 72169 R 283165 CDS YP_031778.1 49473736 2867269 complement(73320..73616) 1 NC_005955.1 phosphocarrier protein 73616 ptsH 2867269 ptsH Bartonella quintana str. Toulouse phosphocarrier protein YP_031778.1 73320 R 283165 CDS YP_031779.1 49473737 2866607 complement(73627..74034) 1 NC_005955.1 fructose-specific IIA component 74034 2866607 BQ00530 Bartonella quintana str. Toulouse fructose-specific IIA component YP_031779.1 73627 R 283165 CDS YP_031780.1 49473738 2867266 complement(74167..74631) 1 NC_005955.1 hypothetical protein 74631 2867266 BQ00540 Bartonella quintana str. Toulouse hypothetical protein YP_031780.1 74167 R 283165 CDS YP_031781.1 49473739 2866372 complement(74655..76439) 1 NC_005955.1 two-component sensor histidine kinase 76439 2866372 BQ00550 Bartonella quintana str. Toulouse two-component sensor histidine kinase YP_031781.1 74655 R 283165 CDS YP_031782.1 49473740 2866490 complement(76479..77201) 1 NC_005955.1 transcriptional regulator 77201 2866490 BQ00560 Bartonella quintana str. Toulouse transcriptional regulator YP_031782.1 76479 R 283165 CDS YP_031783.1 49473741 2866961 77575..78030 1 NC_005955.1 LysM domain/BON superfamily protein 78030 2866961 BQ00570 Bartonella quintana str. Toulouse LysM domain/BON superfamily protein YP_031783.1 77575 D 283165 CDS YP_031784.1 49473742 2866974 complement(78169..78717) 1 NC_005955.1 hypothetical protein 78717 2866974 BQ00580 Bartonella quintana str. Toulouse hypothetical protein YP_031784.1 78169 R 283165 CDS YP_031785.1 49473743 2866711 79609..81501 1 NC_005955.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 81501 dnaK 2866711 dnaK Bartonella quintana str. Toulouse molecular chaperone DnaK YP_031785.1 79609 D 283165 CDS YP_031786.1 49473744 2866620 81660..82802 1 NC_005955.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 82802 dnaJ1 2866620 dnaJ1 Bartonella quintana str. Toulouse molecular chaperone DnaJ YP_031786.1 81660 D 283165 CDS YP_031787.1 49473745 2867036 84547..85452 1 NC_005955.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 85452 argB 2867036 argB Bartonella quintana str. Toulouse acetylglutamate kinase YP_031787.1 84547 D 283165 CDS YP_031788.1 49473746 2866595 85475..86383 1 NC_005955.1 hypothetical protein 86383 2866595 BQ00630 Bartonella quintana str. Toulouse hypothetical protein YP_031788.1 85475 D 283165 CDS YP_031789.1 49473747 2867566 86968..88773 1 NC_005955.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 88773 lepA 2867566 lepA Bartonella quintana str. Toulouse GTP-binding protein LepA YP_031789.1 86968 D 283165 CDS YP_031790.1 49473748 2867249 complement(88850..89698) 1 NC_005955.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 89698 dapD 2867249 dapD Bartonella quintana str. Toulouse 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_031790.1 88850 R 283165 CDS YP_031791.1 49473749 2867410 89804..90667 1 NC_005955.1 hypothetical protein 90667 2867410 BQ00660 Bartonella quintana str. Toulouse hypothetical protein YP_031791.1 89804 D 283165 CDS YP_031792.1 49473750 2867384 complement(90700..91443) 1 NC_005955.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 91443 truA 2867384 truA Bartonella quintana str. Toulouse tRNA pseudouridine synthase A YP_031792.1 90700 R 283165 CDS YP_031793.1 49473751 2867397 complement(91445..92374) 1 NC_005955.1 methionyl-tRNA formyltransferase 92374 fmt 2867397 fmt Bartonella quintana str. Toulouse methionyl-tRNA formyltransferase YP_031793.1 91445 R 283165 CDS YP_031794.1 49473752 2866415 complement(92374..92904) 1 NC_005955.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 92904 def 2866415 def Bartonella quintana str. Toulouse peptide deformylase YP_031794.1 92374 R 283165 CDS YP_031795.1 49473753 2867390 92994..94178 1 NC_005955.1 hypothetical protein 94178 2867390 BQ00700 Bartonella quintana str. Toulouse hypothetical protein YP_031795.1 92994 D 283165 CDS YP_031796.1 49473754 2867398 94286..94873 1 NC_005955.1 hypothetical protein 94873 2867398 BQ00710 Bartonella quintana str. Toulouse hypothetical protein YP_031796.1 94286 D 283165 CDS YP_031797.1 49473755 2867439 complement(96302..96553) 1 NC_005955.1 hypothetical protein 96553 2867439 BQ00720 Bartonella quintana str. Toulouse hypothetical protein YP_031797.1 96302 R 283165 CDS YP_031798.1 49473756 2867385 complement(96579..97010) 1 NC_005955.1 heat shock protein 97010 ibpA1 2867385 ibpA1 Bartonella quintana str. Toulouse heat shock protein YP_031798.1 96579 R 283165 CDS YP_031799.1 49473757 2867158 97118..97858 1 NC_005955.1 endonuclease III 97858 nth 2867158 nth Bartonella quintana str. Toulouse endonuclease III YP_031799.1 97118 D 283165 CDS YP_031800.1 49473758 2866562 98007..98210 1 NC_005955.1 50S ribosomal protein L35 98210 rpmI 2866562 rpmI Bartonella quintana str. Toulouse 50S ribosomal protein L35 YP_031800.1 98007 D 283165 CDS YP_031801.1 49473759 2866502 98244..98645 1 NC_005955.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 98645 rplT 2866502 rplT Bartonella quintana str. Toulouse 50S ribosomal protein L20 YP_031801.1 98244 D 283165 CDS YP_031802.1 49473760 2867409 98740..99825 1 NC_005955.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 99825 pheS 2867409 pheS Bartonella quintana str. Toulouse phenylalanyl-tRNA synthetase subunit alpha YP_031802.1 98740 D 283165 CDS YP_031803.1 49473761 2866356 99857..102271 1 NC_005955.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 102271 pheT 2866356 pheT Bartonella quintana str. Toulouse phenylalanyl-tRNA synthetase subunit beta YP_031803.1 99857 D 283165 CDS YP_031804.1 49473762 2867530 102546..103454 1 NC_005955.1 Iron transport protein yfeA 103454 yfeA 2867530 yfeA Bartonella quintana str. Toulouse Iron transport protein yfeA YP_031804.1 102546 D 283165 CDS YP_031805.1 49473763 2867520 103451..104278 1 NC_005955.1 Iron transport protein yfeB 104278 yfeB 2867520 yfeB Bartonella quintana str. Toulouse Iron transport protein yfeB YP_031805.1 103451 D 283165 CDS YP_031806.1 49473764 2867521 104275..105141 1 NC_005955.1 Iron transport system membrane protein yfeC 105141 yfeC 2867521 yfeC Bartonella quintana str. Toulouse Iron transport system membrane protein yfeC YP_031806.1 104275 D 283165 CDS YP_031807.1 49473765 2867381 105138..106043 1 NC_005955.1 Iron transport system membrane protein yfeD 106043 yfeD 2867381 yfeD Bartonella quintana str. Toulouse Iron transport system membrane protein yfeD YP_031807.1 105138 D 283165 CDS YP_031808.1 49473766 2867571 106455..106841 1 NC_005955.1 hypothetical protein 106841 2867571 BQ00830 Bartonella quintana str. Toulouse hypothetical protein YP_031808.1 106455 D 283165 CDS YP_031809.1 49473767 2866635 complement(107234..108538) 1 NC_005955.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 108538 pncB 2866635 pncB Bartonella quintana str. Toulouse nicotinate phosphoribosyltransferase YP_031809.1 107234 R 283165 CDS YP_031810.1 49473768 2866547 complement(108670..117237) 1 NC_005955.1 cyclic beta 1-2 glucan synthetase 117237 2866547 BQ00850 Bartonella quintana str. Toulouse cyclic beta 1-2 glucan synthetase YP_031810.1 108670 R 283165 CDS YP_031811.1 49473769 2867320 complement(117438..119138) 1 NC_005955.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 119138 rpsA 2867320 rpsA Bartonella quintana str. Toulouse 30S ribosomal protein S1 YP_031811.1 117438 R 283165 CDS YP_031812.1 49473770 2866698 complement(119272..119919) 1 NC_005955.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 119919 cmk 2866698 cmk Bartonella quintana str. Toulouse cytidylate kinase YP_031812.1 119272 R 283165 CDS YP_031813.1 49473771 2866984 complement(119916..121244) 1 NC_005955.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 121244 aroA 2866984 aroA Bartonella quintana str. Toulouse 3-phosphoshikimate 1-carboxyvinyltransferase YP_031813.1 119916 R 283165 CDS YP_031814.1 49473772 2866784 121433..121813 1 NC_005955.1 hypothetical protein 121813 2866784 BQ00890 Bartonella quintana str. Toulouse hypothetical protein YP_031814.1 121433 D 283165 CDS YP_031815.1 49473773 2867263 complement(125213..127948) 1 NC_005955.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 127948 mutS 2867263 mutS Bartonella quintana str. Toulouse DNA mismatch repair protein MutS YP_031815.1 125213 R 283165 CDS YP_031816.1 49473774 2866543 128158..130455 1 NC_005955.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 130455 maeB 2866543 maeB Bartonella quintana str. Toulouse malic enzyme YP_031816.1 128158 D 283165 CDS YP_031817.1 49473775 2867071 complement(130507..130983) 1 NC_005955.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 130983 secB 2867071 secB Bartonella quintana str. Toulouse preprotein translocase subunit SecB YP_031817.1 130507 R 283165 CDS YP_031818.1 49473776 2866600 complement(131125..131628) 1 NC_005955.1 hypothetical protein 131628 2866600 BQ00960 Bartonella quintana str. Toulouse hypothetical protein YP_031818.1 131125 R 283165 CDS YP_031819.1 49473777 2867015 131812..132504 1 NC_005955.1 hypothetical protein 132504 2867015 BQ00970 Bartonella quintana str. Toulouse hypothetical protein YP_031819.1 131812 D 283165 CDS YP_031820.1 49473778 2866944 complement(134082..135083) 1 NC_005955.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 135083 hslO 2866944 hslO Bartonella quintana str. Toulouse heat shock protein 33 YP_031820.1 134082 R 283165 CDS YP_031821.1 49473779 2867003 complement(136061..137254) 1 NC_005955.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase 137254 argD 2867003 argD Bartonella quintana str. Toulouse acetylornithine transaminase YP_031821.1 136061 R 283165 CDS YP_031822.1 49473780 2866946 137737..138270 1 NC_005955.1 hypothetical protein 138270 2866946 BQ01020 Bartonella quintana str. Toulouse hypothetical protein YP_031822.1 137737 D 283165 CDS YP_031823.1 49473781 2866664 complement(139052..139693) 1 NC_005955.1 Thiol 3A-disulfide interchange protein 139693 dsbE 2866664 dsbE Bartonella quintana str. Toulouse Thiol 3A-disulfide interchange protein YP_031823.1 139052 R 283165 CDS YP_031824.1 49473782 2866492 complement(139668..139919) 1 NC_005955.1 hypothetical protein 139919 2866492 BQ01050 Bartonella quintana str. Toulouse hypothetical protein YP_031824.1 139668 R 283165 CDS YP_031825.1 49473783 2866368 complement(139907..140686) 1 NC_005955.1 Heme exporter protein C 140686 ccmC 2866368 ccmC Bartonella quintana str. Toulouse Heme exporter protein C YP_031825.1 139907 R 283165 CDS YP_031826.1 49473784 2867241 complement(140732..141397) 1 NC_005955.1 Heme exporter protein B 141397 ccmB 2867241 ccmB Bartonella quintana str. Toulouse Heme exporter protein B YP_031826.1 140732 R 283165 CDS YP_031827.1 49473785 2867227 complement(141394..142020) 1 NC_005955.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 142020 ccmA 2867227 ccmA Bartonella quintana str. Toulouse cytochrome c biogenesis protein CcmA YP_031827.1 141394 R 283165 CDS YP_031828.1 49473786 2867234 142319..145006 1 NC_005955.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 145006 acnA 2867234 acnA Bartonella quintana str. Toulouse aconitate hydratase YP_031828.1 142319 D 283165 CDS YP_031829.1 49473787 2867041 145233..145499 1 NC_005955.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 145499 rpsT 2867041 rpsT Bartonella quintana str. Toulouse 30S ribosomal protein S20 YP_031829.1 145233 D 283165 CDS YP_031830.1 49473788 2866280 146196..147767 1 NC_005955.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 147767 dnaA 2866280 dnaA Bartonella quintana str. Toulouse chromosome replication initiator DnaA YP_031830.1 146196 D 283165 CDS YP_031831.1 49473789 2866680 147961..149082 1 NC_005955.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 149082 dnaN 2866680 dnaN Bartonella quintana str. Toulouse DNA polymerase III subunit beta YP_031831.1 147961 D 283165 CDS YP_031832.1 49473790 2867572 149103..150236 1 NC_005955.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 150236 recF 2867572 recF Bartonella quintana str. Toulouse recombination protein F YP_031832.1 149103 D 283165 CDS YP_031833.1 49473791 2867083 150289..150735 1 NC_005955.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 150735 aroQ 2867083 aroQ Bartonella quintana str. Toulouse 3-dehydroquinate dehydratase YP_031833.1 150289 D 283165 CDS YP_031834.1 49473792 2867027 150857..151828 1 NC_005955.1 cytochrome o ubiquinol oxidase subunit II 151828 cyoA 2867027 cyoA Bartonella quintana str. Toulouse cytochrome o ubiquinol oxidase subunit II YP_031834.1 150857 D 283165 CDS YP_031835.1 49473793 2867032 151902..153920 1 NC_005955.1 cytochrome o ubiquinol oxidase subunit I 153920 cyoB 2867032 cyoB Bartonella quintana str. Toulouse cytochrome o ubiquinol oxidase subunit I YP_031835.1 151902 D 283165 CDS YP_031836.1 49473794 2867131 153917..154582 1 NC_005955.1 cytochrome o ubiquinol oxidase subunit III 154582 cyoC 2867131 cyoC Bartonella quintana str. Toulouse cytochrome o ubiquinol oxidase subunit III YP_031836.1 153917 D 283165 CDS YP_031837.1 49473795 2867422 154582..155088 1 NC_005955.1 cytochrome o ubiquinol oxidase subunit IV 155088 cyoD 2867422 cyoD Bartonella quintana str. Toulouse cytochrome o ubiquinol oxidase subunit IV YP_031837.1 154582 D 283165 CDS YP_031838.1 49473796 2866978 155521..156543 1 NC_005955.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 156543 gpsA 2866978 gpsA Bartonella quintana str. Toulouse NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_031838.1 155521 D 283165 CDS YP_031839.1 49473797 2867030 complement(156831..157649) 1 NC_005955.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 157649 fabI1 2867030 fabI1 Bartonella quintana str. Toulouse enoyl-ACP reductase YP_031839.1 156831 R 283165 CDS YP_031840.1 49473798 2867230 complement(157698..158918) 1 NC_005955.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 158918 fabB 2867230 fabB Bartonella quintana str. Toulouse 3-oxoacyl-ACP synthase YP_031840.1 157698 R 283165 CDS YP_031841.1 49473799 2867238 complement(158976..159485) 1 NC_005955.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 159485 fabA 2867238 fabA Bartonella quintana str. Toulouse 3-hydroxydecanoyl-ACP dehydratase YP_031841.1 158976 R 283165 CDS YP_031842.1 49473800 2867429 159717..160217 1 NC_005955.1 Iron response regulator 160217 fur1 2867429 fur1 Bartonella quintana str. Toulouse Iron response regulator YP_031842.1 159717 D 283165 CDS YP_031843.1 49473801 2867240 complement(160277..160834) 1 NC_005955.1 hypothetical protein 160834 2867240 BQ01240 Bartonella quintana str. Toulouse hypothetical protein YP_031843.1 160277 R 283165 CDS YP_031844.1 49473802 2866275 complement(161599..161832) 1 NC_005955.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 161832 rpsU 2866275 rpsU Bartonella quintana str. Toulouse 30S ribosomal protein S21 YP_031844.1 161599 R 283165 CDS YP_031845.1 49473803 2866498 164682..165797 1 NC_005955.1 hypothetical protein 165797 2866498 BQ01280 Bartonella quintana str. Toulouse hypothetical protein YP_031845.1 164682 D 283165 CDS YP_031846.1 49473804 2866795 165820..168945 1 NC_005955.1 acriflavin resistance protein d 168945 acrD 2866795 acrD Bartonella quintana str. Toulouse acriflavin resistance protein d YP_031846.1 165820 D 283165 CDS YP_031847.1 49473805 2867079 169137..170816 1 NC_005955.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 170816 pgi 2867079 pgi Bartonella quintana str. Toulouse glucose-6-phosphate isomerase YP_031847.1 169137 D 283165 CDS YP_031848.1 49473806 2866776 171226..171717 1 NC_005955.1 50S ribosomal protein L21 171717 rplU 2866776 rplU Bartonella quintana str. Toulouse 50S ribosomal protein L21 YP_031848.1 171226 D 283165 CDS YP_031849.1 49473807 2866665 171730..171999 1 NC_005955.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 171999 rpmA 2866665 rpmA Bartonella quintana str. Toulouse 50S ribosomal protein L27 YP_031849.1 171730 D 283165 CDS YP_031850.1 49473808 2867407 173436..175949 1 NC_005955.1 multiphosphoryl transfer protein (mtp) 175949 fruB 2867407 fruB Bartonella quintana str. Toulouse multiphosphoryl transfer protein (mtp) YP_031850.1 173436 D 283165 CDS YP_031851.1 49473809 2866495 complement(177995..178216) 1 NC_005955.1 hypothetical protein 178216 2866495 BQ01360 Bartonella quintana str. Toulouse hypothetical protein YP_031851.1 177995 R 283165 CDS YP_031852.1 49473810 2867068 179860..183057 1 NC_005955.1 adhesin 183057 badA1 2867068 badA1 Bartonella quintana str. Toulouse adhesin YP_031852.1 179860 D 283165 CDS YP_031853.1 49473811 2867052 183418..186267 1 NC_005955.1 adhesin 186267 badA2 2867052 badA2 Bartonella quintana str. Toulouse adhesin YP_031853.1 183418 D 283165 CDS YP_031854.1 49473812 2867059 186628..189540 1 NC_005955.1 adhesin 189540 badA3 2867059 badA3 Bartonella quintana str. Toulouse adhesin YP_031854.1 186628 D 283165 CDS YP_031855.1 49473813 2867277 189537..190109 1 NC_005955.1 hypothetical protein 190109 2867277 BQ01420 Bartonella quintana str. Toulouse hypothetical protein YP_031855.1 189537 D 283165 CDS YP_031856.1 49473814 2867522 complement(190705..191211) 1 NC_005955.1 hypothetical protein 191211 2867522 BQ01430 Bartonella quintana str. Toulouse hypothetical protein YP_031856.1 190705 R 283165 CDS YP_031857.1 49473815 2867420 193137..193862 1 NC_005955.1 cell division protein ftsJ 193862 ftsJ 2867420 ftsJ Bartonella quintana str. Toulouse cell division protein ftsJ YP_031857.1 193137 D 283165 CDS YP_031858.1 49473816 2866544 194031..195056 1 NC_005955.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 195056 obgE 2866544 obgE Bartonella quintana str. Toulouse GTPase ObgE YP_031858.1 194031 D 283165 CDS YP_031859.1 49473817 2867517 195040..196194 1 NC_005955.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 196194 proB 2867517 proB Bartonella quintana str. Toulouse gamma-glutamyl kinase YP_031859.1 195040 D 283165 CDS YP_031860.1 49473818 2867258 196262..197500 1 NC_005955.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 197500 proA 2867258 proA Bartonella quintana str. Toulouse gamma-glutamyl phosphate reductase YP_031860.1 196262 D 283165 CDS YP_031861.1 49473819 2867345 197530..198123 1 NC_005955.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 198123 nadD 2867345 nadD Bartonella quintana str. Toulouse nicotinic acid mononucleotide adenylyltransferase YP_031861.1 197530 D 283165 CDS YP_031862.1 49473820 2867401 199204..200484 1 NC_005955.1 filament-A percursor 200484 filA 2867401 filA Bartonella quintana str. Toulouse filament-A percursor YP_031862.1 199204 D 283165 CDS YP_031863.1 49473821 2866654 200474..201799 1 NC_005955.1 carboxy-terminal processing protease ctpA 201799 ctpA 2866654 ctpA Bartonella quintana str. Toulouse carboxy-terminal processing protease ctpA YP_031863.1 200474 D 283165 CDS YP_031864.1 49473822 2866386 201841..202362 1 NC_005955.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 202362 invA 2866386 invA Bartonella quintana str. Toulouse dinucleoside polyphosphate hydrolase YP_031864.1 201841 D 283165 CDS YP_031865.1 49473823 2866387 202474..203034 1 NC_005955.1 invasion-associated protein B 203034 invB 2866387 invB Bartonella quintana str. Toulouse invasion-associated protein B YP_031865.1 202474 D 283165 CDS YP_031866.1 49473824 2867346 203370..203663 1 NC_005955.1 hypothetical protein 203663 2867346 BQ01560 Bartonella quintana str. Toulouse hypothetical protein YP_031866.1 203370 D 283165 CDS YP_031867.1 49473825 2866675 203688..204032 1 NC_005955.1 hypothetical protein 204032 2866675 BQ01570 Bartonella quintana str. Toulouse hypothetical protein YP_031867.1 203688 D 283165 CDS YP_031868.1 49473826 2866912 complement(204047..204577) 1 NC_005955.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 204577 ppa 2866912 ppa Bartonella quintana str. Toulouse inorganic pyrophosphatase YP_031868.1 204047 R 283165 CDS YP_031869.1 49473827 2866527 complement(204646..206472) 1 NC_005955.1 GTP-binding protein TypA 206472 typA 2866527 typA Bartonella quintana str. Toulouse GTP-binding protein TypA YP_031869.1 204646 R 283165 CDS YP_031870.1 49473828 2866717 complement(207716..209092) 1 NC_005955.1 Mg2+ transport protein 209092 mgtE 2866717 mgtE Bartonella quintana str. Toulouse Mg2+ transport protein YP_031870.1 207716 R 283165 CDS YP_031871.1 49473829 2867140 complement(211634..212701) 1 NC_005955.1 hypothetical protein 212701 2867140 BQ01620 Bartonella quintana str. Toulouse hypothetical protein YP_031871.1 211634 R 283165 CDS YP_031872.1 49473830 2867141 complement(212713..213969) 1 NC_005955.1 peptidoglycan-binding protein 213969 2867141 BQ01630 Bartonella quintana str. Toulouse peptidoglycan-binding protein YP_031872.1 212713 R 283165 CDS YP_031873.1 49473831 2867437 214238..215128 1 NC_005955.1 UTP-glucose-1-phosphate uridylyltransferase 215128 galU 2867437 galU Bartonella quintana str. Toulouse UTP-glucose-1-phosphate uridylyltransferase YP_031873.1 214238 D 283165 CDS YP_031874.1 49473832 2866798 215168..216163 1 NC_005955.1 polysialic acid capsule expression protein 216163 2866798 BQ01650 Bartonella quintana str. Toulouse polysialic acid capsule expression protein YP_031874.1 215168 D 283165 CDS YP_031875.1 49473833 2866466 complement(216450..216809) 1 NC_005955.1 Outer membrane lipoprotein precursor 216809 2866466 BQ01660 Bartonella quintana str. Toulouse Outer membrane lipoprotein precursor YP_031875.1 216450 R 283165 CDS YP_031876.1 49473834 2867157 217061..218446 1 NC_005955.1 sigma 54 activator-like protein 218446 2867157 BQ01670 Bartonella quintana str. Toulouse sigma 54 activator-like protein YP_031876.1 217061 D 283165 CDS YP_031877.1 49473835 2867145 218881..220452 1 NC_005955.1 phopholipase D-family protein 220452 2867145 BQ01680 Bartonella quintana str. Toulouse phopholipase D-family protein YP_031877.1 218881 D 283165 CDS YP_031878.1 49473836 2867591 220604..222103 1 NC_005955.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 222103 guaB 2867591 guaB Bartonella quintana str. Toulouse inosine 5'-monophosphate dehydrogenase YP_031878.1 220604 D 283165 CDS YP_031879.1 49473837 2866633 222926..224212 1 NC_005955.1 SUN protein (Fmu protein) 224212 sun1 2866633 sun1 Bartonella quintana str. Toulouse SUN protein (Fmu protein) YP_031879.1 222926 D 283165 CDS YP_031880.1 49473838 2867605 224344..225900 1 NC_005955.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 225900 guaA 2867605 guaA Bartonella quintana str. Toulouse GMP synthase YP_031880.1 224344 D 283165 CDS YP_031881.1 49473839 2866584 226035..226799 1 NC_005955.1 hypothetical protein 226799 2866584 BQ01720 Bartonella quintana str. Toulouse hypothetical protein YP_031881.1 226035 D 283165 CDS YP_031882.1 49473840 2866553 complement(226915..227961) 1 NC_005955.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 227961 ugpC 2866553 ugpC Bartonella quintana str. Toulouse glycerol-3-phosphate transporter ATP-binding subunit YP_031882.1 226915 R 283165 CDS YP_031883.1 49473841 2867340 complement(227964..228815) 1 NC_005955.1 sn-glycerol-3-phosphate transport system permease protein ugpE 228815 ugpE 2867340 ugpE Bartonella quintana str. Toulouse sn-glycerol-3-phosphate transport system permease protein ugpE YP_031883.1 227964 R 283165 CDS YP_031884.1 49473842 2866565 complement(228826..229710) 1 NC_005955.1 sn-glycerol-3-phosphate transport system permease protein ugpA 229710 ugpA 2866565 ugpA Bartonella quintana str. Toulouse sn-glycerol-3-phosphate transport system permease protein ugpA YP_031884.1 228826 R 283165 CDS YP_031885.1 49473843 2866566 complement(229821..231146) 1 NC_005955.1 glycerol-3-phosphate-binding periplasmic protein precursor ugpB 231146 ugpB 2866566 ugpB Bartonella quintana str. Toulouse glycerol-3-phosphate-binding periplasmic protein precursor ugpB YP_031885.1 229821 R 283165 CDS YP_031886.1 49473844 2867137 complement(231525..232451) 1 NC_005955.1 ABC transporter periplasmic binding protein 232451 2867137 BQ01770 Bartonella quintana str. Toulouse ABC transporter periplasmic binding protein YP_031886.1 231525 R 283165 CDS YP_031887.1 49473845 2867094 complement(232461..233333) 1 NC_005955.1 ABC transporter permease 233333 2867094 BQ01780 Bartonella quintana str. Toulouse ABC transporter permease YP_031887.1 232461 R 283165 CDS YP_031888.1 49473846 2867152 complement(233337..234089) 1 NC_005955.1 ABC transporter ATP-binding protein 234089 2867152 BQ01790 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_031888.1 233337 R 283165 CDS YP_031889.1 49473847 2867599 234779..235003 1 NC_005955.1 glutaredoxin-like protein nrdH 235003 nrdH 2867599 nrdH Bartonella quintana str. Toulouse glutaredoxin-like protein nrdH YP_031889.1 234779 D 283165 CDS YP_031890.1 49473848 2867016 235003..235401 1 NC_005955.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 235401 nrdI 2867016 nrdI Bartonella quintana str. Toulouse ribonucleotide reductase stimulatory protein YP_031890.1 235003 D 283165 CDS YP_031891.1 49473849 2867614 235383..237533 1 NC_005955.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 237533 nrdE 2867614 nrdE Bartonella quintana str. Toulouse ribonucleotide-diphosphate reductase subunit alpha YP_031891.1 235383 D 283165 CDS YP_031892.1 49473850 2867615 237545..238519 1 NC_005955.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 238519 nrdF 2867615 nrdF Bartonella quintana str. Toulouse ribonucleotide-diphosphate reductase subunit beta YP_031892.1 237545 D 283165 CDS YP_031893.1 49473851 2866438 complement(238516..239382) 1 NC_005955.1 protoporphyrinogen oxidase 239382 hemK 2866438 hemK Bartonella quintana str. Toulouse protoporphyrinogen oxidase YP_031893.1 238516 R 283165 CDS YP_031894.1 49473852 2866949 complement(239379..240458) 1 NC_005955.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 240458 prfA 2866949 prfA Bartonella quintana str. Toulouse peptide chain release factor 1 YP_031894.1 239379 R 283165 CDS YP_031895.1 49473853 2866367 complement(240658..241074) 1 NC_005955.1 Iron response regulator 241074 fur2 2866367 fur2 Bartonella quintana str. Toulouse Iron response regulator YP_031895.1 240658 R 283165 CDS YP_031896.1 49473854 2866581 complement(241092..243812) 1 NC_005955.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 243812 secA 2866581 secA Bartonella quintana str. Toulouse preprotein translocase subunit SecA YP_031896.1 241092 R 283165 CDS YP_031897.1 49473855 2867198 244232..245185 1 NC_005955.1 peptidyl-prolyl cis-trans isomerase 245185 2867198 BQ01880 Bartonella quintana str. Toulouse peptidyl-prolyl cis-trans isomerase YP_031897.1 244232 D 283165 CDS YP_031898.1 49473856 2866994 245302..246540 1 NC_005955.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 246540 argJ 2866994 argJ Bartonella quintana str. Toulouse bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_031898.1 245302 D 283165 CDS YP_031899.1 49473857 2867290 246681..247094 1 NC_005955.1 Mutator mutT protein 247094 mutT 2867290 mutT Bartonella quintana str. Toulouse Mutator mutT protein YP_031899.1 246681 D 283165 CDS YP_031900.1 49473858 2866613 complement(247604..248467) 1 NC_005955.1 hypothetical protein 248467 2866613 BQ01910 Bartonella quintana str. Toulouse hypothetical protein YP_031900.1 247604 R 283165 CDS YP_031901.1 49473859 2867284 complement(248625..249992) 1 NC_005955.1 leucyl aminopeptidase 249992 pepA 2867284 pepA Bartonella quintana str. Toulouse leucyl aminopeptidase YP_031901.1 248625 R 283165 CDS YP_031902.1 49473860 2867019 complement(250006..251004) 1 NC_005955.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 251004 coaA 2867019 coaA Bartonella quintana str. Toulouse pantothenate kinase YP_031902.1 250006 R 283165 CDS YP_031903.1 49473861 2866569 complement(251126..252115) 1 NC_005955.1 L-asparaginase 252115 ansA 2866569 ansA Bartonella quintana str. Toulouse L-asparaginase YP_031903.1 251126 R 283165 CDS YP_031904.1 49473862 2867138 252318..252899 1 NC_005955.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 252899 hslV 2867138 hslV Bartonella quintana str. Toulouse ATP-dependent protease peptidase subunit YP_031904.1 252318 D 283165 CDS YP_031905.1 49473863 2866787 252900..254210 1 NC_005955.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 254210 hslU 2866787 hslU Bartonella quintana str. Toulouse ATP-dependent protease ATP-binding subunit HslU YP_031905.1 252900 D 283165 CDS YP_031906.1 49473864 2866276 complement(254230..255258) 1 NC_005955.1 ribosomal RNA small subunit methyltransferase c 255258 rsmC 2866276 rsmC Bartonella quintana str. Toulouse ribosomal RNA small subunit methyltransferase c YP_031906.1 254230 R 283165 CDS YP_031907.1 49473865 2866682 complement(255297..257498) 1 NC_005955.1 polynucleotide phosphorylase 257498 pnp 2866682 pnp Bartonella quintana str. Toulouse polynucleotide phosphorylase YP_031907.1 255297 R 283165 CDS YP_031908.1 49473866 2867097 complement(257765..258034) 1 NC_005955.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 258034 rpsO 2867097 rpsO Bartonella quintana str. Toulouse 30S ribosomal protein S15 YP_031908.1 257765 R 283165 CDS YP_031909.1 49473867 2866818 258352..259980 1 NC_005955.1 transport transmembrane protein 259980 2866818 BQ02000 Bartonella quintana str. Toulouse transport transmembrane protein YP_031909.1 258352 D 283165 CDS YP_031910.1 49473868 2867382 complement(260215..261027) 1 NC_005955.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 261027 truB 2867382 truB Bartonella quintana str. Toulouse tRNA pseudouridine synthase B YP_031910.1 260215 R 283165 CDS YP_031911.1 49473869 2867160 complement(261032..261439) 1 NC_005955.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 261439 rbfA 2867160 rbfA Bartonella quintana str. Toulouse ribosome-binding factor A YP_031911.1 261032 R 283165 CDS YP_031912.1 49473870 2866384 complement(261563..264100) 1 NC_005955.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 264100 infB 2866384 infB Bartonella quintana str. Toulouse translation initiation factor IF-2 YP_031912.1 261563 R 283165 CDS YP_031913.1 49473871 2866484 complement(264131..264730) 1 NC_005955.1 hypothetical protein 264730 2866484 BQ02040 Bartonella quintana str. Toulouse hypothetical protein YP_031913.1 264131 R 283165 CDS YP_031914.1 49473872 2866858 complement(264731..266362) 1 NC_005955.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 266362 nusA 2866858 nusA Bartonella quintana str. Toulouse transcription elongation factor NusA YP_031914.1 264731 R 283165 CDS YP_031915.1 49473873 2866630 complement(266412..267062) 1 NC_005955.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 267062 2866630 BQ02060 Bartonella quintana str. Toulouse hypothetical protein YP_031915.1 266412 R 283165 CDS YP_031916.1 49473874 2867286 complement(267190..267891) 1 NC_005955.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 267891 trmB 2867286 trmB Bartonella quintana str. Toulouse tRNA (guanine-N(7)-)-methyltransferase YP_031916.1 267190 R 283165 CDS YP_031917.1 49473875 2866462 complement(267888..269156) 1 NC_005955.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 269156 metK 2866462 metK Bartonella quintana str. Toulouse S-adenosylmethionine synthetase YP_031917.1 267888 R 283165 CDS YP_031918.1 49473876 2866623 complement(269272..269685) 1 NC_005955.1 transcriptional regulator 269685 2866623 BQ02090 Bartonella quintana str. Toulouse transcriptional regulator YP_031918.1 269272 R 283165 CDS YP_031919.1 49473877 2867179 complement(269832..271466) 1 NC_005955.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 271466 lnt 2867179 lnt Bartonella quintana str. Toulouse apolipoprotein N-acyltransferase YP_031919.1 269832 R 283165 CDS YP_031920.1 49473878 2867215 complement(271429..272448) 1 NC_005955.1 hemolysin 272448 tlyC 2867215 tlyC Bartonella quintana str. Toulouse hemolysin YP_031920.1 271429 R 283165 CDS YP_031921.1 49473879 2867204 complement(272546..273022) 1 NC_005955.1 hypothetical protein 273022 2867204 BQ02120 Bartonella quintana str. Toulouse hypothetical protein YP_031921.1 272546 R 283165 CDS YP_031922.1 49473880 2866352 complement(273035..274144) 1 NC_005955.1 phosphate starvation-induced protein phoH 274144 phoH 2866352 phoH Bartonella quintana str. Toulouse phosphate starvation-induced protein phoH YP_031922.1 273035 R 283165 CDS YP_031923.1 49473881 2867077 complement(274222..275598) 1 NC_005955.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 275598 2867077 BQ02140 Bartonella quintana str. Toulouse (dimethylallyl)adenosine tRNA methylthiotransferase YP_031923.1 274222 R 283165 CDS YP_031924.1 49473882 2866780 complement(275630..276121) 1 NC_005955.1 peptide N-acetyltransferase 276121 2866780 BQ02150 Bartonella quintana str. Toulouse peptide N-acetyltransferase YP_031924.1 275630 R 283165 CDS YP_031925.1 49473883 2867184 complement(276121..276804) 1 NC_005955.1 hypothetical protein 276804 2867184 BQ02160 Bartonella quintana str. Toulouse hypothetical protein YP_031925.1 276121 R 283165 CDS YP_031926.1 49473884 2867243 complement(278538..279143) 1 NC_005955.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 279143 recR 2867243 recR Bartonella quintana str. Toulouse recombination protein RecR YP_031926.1 278538 R 283165 CDS YP_031927.1 49473885 2866489 complement(279178..279504) 1 NC_005955.1 hypothetical protein 279504 2866489 BQ02190 Bartonella quintana str. Toulouse hypothetical protein YP_031927.1 279178 R 283165 CDS YP_031928.1 49473886 2866701 complement(279519..281441) 1 NC_005955.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 281441 dnaX 2866701 dnaX Bartonella quintana str. Toulouse DNA polymerase III subunits gamma and tau YP_031928.1 279519 R 283165 CDS YP_031929.1 49473887 2867537 complement(282744..283151) 1 NC_005955.1 hypothetical protein 283151 2867537 BQ02210 Bartonella quintana str. Toulouse hypothetical protein YP_031929.1 282744 R 283165 CDS YP_031930.1 49473888 2866960 complement(284438..285169) 1 NC_005955.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 285169 kdsB 2866960 kdsB Bartonella quintana str. Toulouse 3-deoxy-manno-octulosonate cytidylyltransferase YP_031930.1 284438 R 283165 CDS YP_031931.1 49473889 2866799 285276..285815 1 NC_005955.1 hypothetical protein 285815 2866799 BQ02240 Bartonella quintana str. Toulouse hypothetical protein YP_031931.1 285276 D 283165 CDS YP_031932.1 49473890 2866651 complement(289611..290399) 1 NC_005955.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 290399 moeB 2866651 moeB Bartonella quintana str. Toulouse molybdopterin biosynthesis protein MoeB YP_031932.1 289611 R 283165 CDS YP_031933.1 49473891 2867395 290488..291426 1 NC_005955.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 291426 gshB 2867395 gshB Bartonella quintana str. Toulouse glutathione synthetase YP_031933.1 290488 D 283165 CDS YP_031934.1 49473892 2867208 291576..292622 1 NC_005955.1 periplasmic phosphate binding protein 292622 2867208 BQ02300 Bartonella quintana str. Toulouse periplasmic phosphate binding protein YP_031934.1 291576 D 283165 CDS YP_031935.1 49473893 2867194 292683..294143 1 NC_005955.1 ABC transporter permease 294143 2867194 BQ02310 Bartonella quintana str. Toulouse ABC transporter permease YP_031935.1 292683 D 283165 CDS YP_031936.1 49473894 2866672 294140..295432 1 NC_005955.1 phosphate ABC transporter permease 295432 pstA 2866672 pstA Bartonella quintana str. Toulouse phosphate ABC transporter permease YP_031936.1 294140 D 283165 CDS YP_031937.1 49473895 2866704 295491..296249 1 NC_005955.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 296249 pstB 2866704 pstB Bartonella quintana str. Toulouse phosphate transporter ATP-binding protein YP_031937.1 295491 D 283165 CDS YP_031938.1 49473896 2867195 296271..296993 1 NC_005955.1 phosphate transporter PhoU 296993 phoU 2867195 phoU Bartonella quintana str. Toulouse phosphate transporter PhoU YP_031938.1 296271 D 283165 CDS YP_031939.1 49473897 2867242 297759..298619 1 NC_005955.1 hypothetical protein 298619 2867242 BQ02350 Bartonella quintana str. Toulouse hypothetical protein YP_031939.1 297759 D 283165 CDS YP_031940.1 49473898 2867103 298651..299898 1 NC_005955.1 aminopeptidase 299898 2867103 BQ02360 Bartonella quintana str. Toulouse aminopeptidase YP_031940.1 298651 D 283165 CDS YP_031941.1 49473899 2866609 299957..300832 1 NC_005955.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 300832 mutM 2866609 mutM Bartonella quintana str. Toulouse formamidopyrimidine-DNA glycosylase YP_031941.1 299957 D 283165 CDS YP_031942.1 49473900 2866351 300916..302304 1 NC_005955.1 hypothetical protein 302304 2866351 BQ02380 Bartonella quintana str. Toulouse hypothetical protein YP_031942.1 300916 D 283165 CDS YP_031943.1 49473901 2867233 302305..302925 1 NC_005955.1 ribonuclease d 302925 rnd1 2867233 rnd1 Bartonella quintana str. Toulouse ribonuclease d YP_031943.1 302305 D 283165 CDS YP_031944.1 49473902 2866825 303521..303838 1 NC_005955.1 hypothetical protein 303838 2866825 BQ02400 Bartonella quintana str. Toulouse hypothetical protein YP_031944.1 303521 D 283165 CDS YP_031945.1 49473903 2867363 305016..305849 1 NC_005955.1 hemin binding protein c 305849 hpbC 2867363 hpbC Bartonella quintana str. Toulouse hemin binding protein c YP_031945.1 305016 D 283165 CDS YP_031946.1 49473904 2867126 306185..307003 1 NC_005955.1 hemin binding protein a 307003 hbpA 2867126 hbpA Bartonella quintana str. Toulouse hemin binding protein a YP_031946.1 306185 D 283165 CDS YP_031947.1 49473905 2867611 307496..308857 1 NC_005955.1 hemin binding protein b 308857 hbpB 2867611 hbpB Bartonella quintana str. Toulouse hemin binding protein b YP_031947.1 307496 D 283165 CDS YP_031948.1 49473906 2866644 309110..312025 1 NC_005955.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 312025 ileS 2866644 ileS Bartonella quintana str. Toulouse isoleucyl-tRNA synthetase YP_031948.1 309110 D 283165 CDS YP_031949.1 49473907 2867155 312231..312830 1 NC_005955.1 hypothetical protein 312830 2867155 BQ02450 Bartonella quintana str. Toulouse hypothetical protein YP_031949.1 312231 D 283165 CDS YP_031950.1 49473908 2867142 complement(312911..313357) 1 NC_005955.1 nitrogen fixation protein 313357 2867142 BQ02460 Bartonella quintana str. Toulouse nitrogen fixation protein YP_031950.1 312911 R 283165 CDS YP_031951.1 49473909 2867143 313618..315021 1 NC_005955.1 hypothetical protein 315021 2867143 BQ02470 Bartonella quintana str. Toulouse hypothetical protein YP_031951.1 313618 D 283165 CDS YP_031952.1 49473910 2866577 315002..315559 1 NC_005955.1 hypothetical protein 315559 2866577 BQ02480 Bartonella quintana str. Toulouse hypothetical protein YP_031952.1 315002 D 283165 CDS YP_031953.1 49473911 2866578 316852..317100 1 NC_005955.1 hypothetical protein 317100 2866578 BQ02490 Bartonella quintana str. Toulouse hypothetical protein YP_031953.1 316852 D 283165 CDS YP_031954.1 49473912 2866785 318414..319745 1 NC_005955.1 pmbA protein, maturation of antibiotic mccb17 319745 pmbA 2866785 pmbA Bartonella quintana str. Toulouse pmbA protein, maturation of antibiotic mccb17 YP_031954.1 318414 D 283165 CDS YP_031955.1 49473913 2866699 319810..320535 1 NC_005955.1 myo-inositol monophosphatase 320535 2866699 BQ02520 Bartonella quintana str. Toulouse myo-inositol monophosphatase YP_031955.1 319810 D 283165 CDS YP_031956.1 49473914 2866714 320581..320826 1 NC_005955.1 hypothetical protein 320826 2866714 BQ02530 Bartonella quintana str. Toulouse hypothetical protein YP_031956.1 320581 D 283165 CDS YP_031957.1 49473915 2867430 321667..322989 1 NC_005955.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 322989 kdtA 2867430 kdtA Bartonella quintana str. Toulouse 3-deoxy-D-manno-octulosonic-acid transferase YP_031957.1 321667 D 283165 CDS YP_031958.1 49473916 2867459 322979..324010 1 NC_005955.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 324010 lpxK 2867459 lpxK Bartonella quintana str. Toulouse tetraacyldisaccharide 4'-kinase YP_031958.1 322979 D 283165 CDS YP_031959.1 49473917 2867464 complement(324043..324279) 1 NC_005955.1 hypothetical protein 324279 2867464 BQ02560 Bartonella quintana str. Toulouse hypothetical protein YP_031959.1 324043 R 283165 CDS YP_031960.1 49473918 2866853 complement(324406..326244) 1 NC_005955.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 326244 mutL 2866853 mutL Bartonella quintana str. Toulouse DNA mismatch repair protein YP_031960.1 324406 R 283165 CDS YP_031961.1 49473919 2867465 326543..327631 1 NC_005955.1 Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 327631 2867465 BQ02580 Bartonella quintana str. Toulouse 2'-deoxycytidine 5'-triphosphate deaminase YP_031961.1 326543 D 283165 CDS YP_031962.1 49473920 2867178 328614..329765 1 NC_005955.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 329765 lldD 2867178 lldD Bartonella quintana str. Toulouse L-lactate dehydrogenase YP_031962.1 328614 D 283165 CDS YP_031963.1 49473921 2866576 complement(331695..332357) 1 NC_005955.1 Phage related lysozyme 332357 2866576 BQ02630 Bartonella quintana str. Toulouse Phage related lysozyme YP_031963.1 331695 R 283165 CDS YP_031964.1 49473922 2866683 complement(337697..338017) 1 NC_005955.1 hypothetical protein 338017 2866683 BQ02680 Bartonella quintana str. Toulouse hypothetical protein YP_031964.1 337697 R 283165 CDS YP_031965.1 49473923 2867408 338201..339631 1 NC_005955.1 phenylalanine-specific permease 339631 pheP 2867408 pheP Bartonella quintana str. Toulouse phenylalanine-specific permease YP_031965.1 338201 D 283165 CDS YP_031966.1 49473924 2866761 339673..340353 1 NC_005955.1 ABC transporter ATP-binding protein 340353 2866761 BQ02700 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_031966.1 339673 D 283165 CDS YP_031967.1 49473925 2866762 340350..340988 1 NC_005955.1 hypothetical protein 340988 2866762 BQ02710 Bartonella quintana str. Toulouse hypothetical protein YP_031967.1 340350 D 283165 CDS YP_031968.1 49473926 2867281 341004..341558 1 NC_005955.1 biotin synthase 341558 2867281 BQ02720 Bartonella quintana str. Toulouse biotin synthase YP_031968.1 341004 D 283165 CDS YP_031969.1 49473927 2867344 341702..341911 1 NC_005955.1 hypothetical protein 341911 2867344 BQ02730 Bartonella quintana str. Toulouse hypothetical protein YP_031969.1 341702 D 283165 CDS YP_031970.1 49473928 2866325 345113..346276 1 NC_005955.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 346276 serC 2866325 serC Bartonella quintana str. Toulouse phosphoserine aminotransferase YP_031970.1 345113 D 283165 CDS YP_031971.1 49473929 2867279 346653..347942 1 NC_005955.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 347942 purA 2867279 purA Bartonella quintana str. Toulouse adenylosuccinate synthetase YP_031971.1 346653 D 283165 CDS YP_031972.1 49473930 2866396 348183..349610 1 NC_005955.1 hypothetical protein 349610 2866396 BQ02810 Bartonella quintana str. Toulouse hypothetical protein YP_031972.1 348183 D 283165 CDS YP_031973.1 49473931 2867334 complement(349755..350639) 1 NC_005955.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 350639 rpoH1 2867334 rpoH1 Bartonella quintana str. Toulouse RNA polymerase factor sigma-32 YP_031973.1 349755 R 283165 CDS YP_031974.1 49473932 2867236 complement(350787..351791) 1 NC_005955.1 ribosomal large subunit pseudouridine synthase D 351791 rluD 2867236 rluD Bartonella quintana str. Toulouse ribosomal large subunit pseudouridine synthase D YP_031974.1 350787 R 283165 CDS YP_031975.1 49473933 2866676 complement(351824..353254) 1 NC_005955.1 aldehyde dehydrogenase 353254 aldA 2866676 aldA Bartonella quintana str. Toulouse aldehyde dehydrogenase YP_031975.1 351824 R 283165 CDS YP_031976.1 49473934 2866856 353705..356260 1 NC_005955.1 cell division transmembrane protein 356260 2866856 BQ02850 Bartonella quintana str. Toulouse cell division transmembrane protein YP_031976.1 353705 D 283165 CDS YP_031977.1 49473935 2866416 356443..357249 1 NC_005955.1 sensory box histidine kinase 357249 2866416 BQ02860 Bartonella quintana str. Toulouse sensory box histidine kinase YP_031977.1 356443 D 283165 CDS YP_031978.1 49473936 2867161 357391..358698 1 NC_005955.1 hypothetical protein 358698 2867161 BQ02870 Bartonella quintana str. Toulouse hypothetical protein YP_031978.1 357391 D 283165 CDS YP_031979.1 49473937 2866514 complement(358713..359126) 1 NC_005955.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 359126 mscL 2866514 mscL Bartonella quintana str. Toulouse large-conductance mechanosensitive channel YP_031979.1 358713 R 283165 CDS YP_031980.1 49473938 2867078 359714..360802 1 NC_005955.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 360802 pyrD 2867078 pyrD Bartonella quintana str. Toulouse dihydroorotate dehydrogenase 2 YP_031980.1 359714 D 283165 CDS YP_031981.1 49473939 2867116 361194..362615 1 NC_005955.1 glutamine synthetase 362615 glnA1 2867116 glnA1 Bartonella quintana str. Toulouse glutamine synthetase YP_031981.1 361194 D 283165 CDS YP_031982.1 49473940 2867318 362627..363910 1 NC_005955.1 oxidoreductase 363910 2867318 BQ02920 Bartonella quintana str. Toulouse oxidoreductase YP_031982.1 362627 D 283165 CDS YP_031983.1 49473941 2867368 364029..365504 1 NC_005955.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 365504 zwf 2867368 zwf Bartonella quintana str. Toulouse glucose-6-phosphate 1-dehydrogenase YP_031983.1 364029 D 283165 CDS YP_031984.1 49473942 2867086 365516..366283 1 NC_005955.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 366283 pgl 2867086 pgl Bartonella quintana str. Toulouse 6-phosphogluconolactonase YP_031984.1 365516 D 283165 CDS YP_031985.1 49473943 2867405 complement(368201..369100) 1 NC_005955.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 369100 folD 2867405 folD Bartonella quintana str. Toulouse bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_031985.1 368201 R 283165 CDS YP_031986.1 49473944 2866399 369415..371295 1 NC_005955.1 hypothetical protein 371295 2866399 BQ02970 Bartonella quintana str. Toulouse hypothetical protein YP_031986.1 369415 D 283165 CDS YP_031987.1 49473945 2867092 371758..372492 1 NC_005955.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 372492 2867092 BQ02980 Bartonella quintana str. Toulouse 16S ribosomal RNA methyltransferase RsmE YP_031987.1 371758 D 283165 CDS YP_031988.1 49473946 2867426 372570..373943 1 NC_005955.1 glutamate-cysteine ligase 373943 gshA 2867426 gshA Bartonella quintana str. Toulouse glutamate-cysteine ligase YP_031988.1 372570 D 283165 CDS YP_031989.1 49473947 2866541 374582..375937 1 NC_005955.1 Sodium /dicarboxylate symporter 375937 2866541 BQ03010 Bartonella quintana str. Toulouse Sodium /dicarboxylate symporter YP_031989.1 374582 D 283165 CDS YP_031990.1 49473948 2866324 complement(376041..376751) 1 NC_005955.1 hypothetical protein 376751 2866324 BQ03020 Bartonella quintana str. Toulouse hypothetical protein YP_031990.1 376041 R 283165 CDS YP_031991.1 49473949 2866986 377034..377819 1 NC_005955.1 competence protein comF 377819 comF 2866986 comF Bartonella quintana str. Toulouse competence protein comF YP_031991.1 377034 D 283165 CDS YP_031992.1 49473950 2867618 377868..378125 1 NC_005955.1 glutaredoxin 378125 grxC 2867618 grxC Bartonella quintana str. Toulouse glutaredoxin YP_031992.1 377868 D 283165 CDS YP_031993.1 49473951 2866690 complement(378148..378891) 1 NC_005955.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 378891 ubiG 2866690 ubiG Bartonella quintana str. Toulouse 3-demethylubiquinone-9 3-methyltransferase YP_031993.1 378148 R 283165 CDS YP_031994.1 49473952 2867224 379084..380340 1 NC_005955.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 380340 lysC 2867224 lysC Bartonella quintana str. Toulouse aspartate kinase YP_031994.1 379084 D 283165 CDS YP_031995.1 49473953 2866393 complement(381265..382641) 1 NC_005955.1 Na+/H antiporter 382641 nhaA 2866393 nhaA Bartonella quintana str. Toulouse Na+/H antiporter YP_031995.1 381265 R 283165 CDS YP_031996.1 49473954 2866449 complement(382793..384484) 1 NC_005955.1 hypothetical protein 384484 2866449 BQ03080 Bartonella quintana str. Toulouse hypothetical protein YP_031996.1 382793 R 283165 CDS YP_031997.1 49473955 2866452 384854..386626 1 NC_005955.1 hypothetical protein 386626 2866452 BQ03090 Bartonella quintana str. Toulouse hypothetical protein YP_031997.1 384854 D 283165 CDS YP_031998.1 49473956 2866395 387270..387941 1 NC_005955.1 hypothetical protein 387941 2866395 BQ03100 Bartonella quintana str. Toulouse hypothetical protein YP_031998.1 387270 D 283165 CDS YP_031999.1 49473957 2867354 387946..389379 1 NC_005955.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 389379 engA 2867354 engA Bartonella quintana str. Toulouse GTP-binding protein EngA YP_031999.1 387946 D 283165 CDS YP_032000.1 49473958 2867527 390104..390511 1 NC_005955.1 hypothetical protein 390511 2867527 BQ03120 Bartonella quintana str. Toulouse hypothetical protein YP_032000.1 390104 D 283165 CDS YP_032001.1 49473959 2866563 390535..391293 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 391293 atpB 2866563 atpB Bartonella quintana str. Toulouse ATP synthase F0F1 subunit A YP_032001.1 390535 D 283165 CDS YP_032002.1 49473960 2866828 391348..391578 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 391578 atpE 2866828 atpE Bartonella quintana str. Toulouse ATP synthase F0F1 subunit C YP_032002.1 391348 D 283165 CDS YP_032003.1 49473961 2867276 391718..392284 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; ATP synthase F0F1 subunit B' 392284 atpF1 2867276 atpF1 Bartonella quintana str. Toulouse ATP synthase F0F1 subunit B' YP_032003.1 391718 D 283165 CDS YP_032004.1 49473962 2867070 392296..392790 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 392790 atpF2 2867070 atpF2 Bartonella quintana str. Toulouse ATP synthase F0F1 subunit B YP_032004.1 392296 D 283165 CDS YP_032005.1 49473963 2866832 complement(393475..395697) 1 NC_005955.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 395697 glyS 2866832 glyS Bartonella quintana str. Toulouse glycyl-tRNA synthetase subunit beta YP_032005.1 393475 R 283165 CDS YP_032006.1 49473964 2867060 complement(395697..396641) 1 NC_005955.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 396641 glyQ 2867060 glyQ Bartonella quintana str. Toulouse glycyl-tRNA synthetase subunit alpha YP_032006.1 395697 R 283165 CDS YP_032007.1 49473965 2867361 complement(396744..398438) 1 NC_005955.1 hypothetical protein 398438 2867361 BQ03190 Bartonella quintana str. Toulouse hypothetical protein YP_032007.1 396744 R 283165 CDS YP_032008.1 49473966 2866389 complement(398532..399602) 1 NC_005955.1 octaprenyl-diphosphate synthase 399602 ispB 2866389 ispB Bartonella quintana str. Toulouse octaprenyl-diphosphate synthase YP_032008.1 398532 R 283165 CDS YP_032009.1 49473967 2866892 399804..400595 1 NC_005955.1 hypothetical protein 400595 2866892 BQ03210 Bartonella quintana str. Toulouse hypothetical protein YP_032009.1 399804 D 283165 CDS YP_032010.1 49473968 2867504 400792..401643 1 NC_005955.1 protease sohB 401643 sohB 2867504 sohB Bartonella quintana str. Toulouse protease sohB YP_032010.1 400792 D 283165 CDS YP_032011.1 49473969 2866968 401900..402808 1 NC_005955.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 402808 thrB 2866968 thrB Bartonella quintana str. Toulouse 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_032011.1 401900 D 283165 CDS YP_032012.1 49473970 2867533 404000..404440 1 NC_005955.1 hypothetical protein 404440 2867533 BQ03250 Bartonella quintana str. Toulouse hypothetical protein YP_032012.1 404000 D 283165 CDS YP_032013.1 49473971 2866916 complement(405109..406212) 1 NC_005955.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 406212 2866916 BQ03260 Bartonella quintana str. Toulouse GTP-dependent nucleic acid-binding protein EngD YP_032013.1 405109 R 283165 CDS YP_032014.1 49473972 2866922 406433..407209 1 NC_005955.1 hypothetical protein 407209 2866922 BQ03270 Bartonella quintana str. Toulouse hypothetical protein YP_032014.1 406433 D 283165 CDS YP_032015.1 49473973 2867298 complement(408545..409126) 1 NC_005955.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 409126 pth 2867298 pth Bartonella quintana str. Toulouse peptidyl-tRNA hydrolase YP_032015.1 408545 R 283165 CDS YP_032016.1 49473974 2866702 complement(409208..409834) 1 NC_005955.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 409834 rplY 2866702 rplY Bartonella quintana str. Toulouse 50S ribosomal protein L25 YP_032016.1 409208 R 283165 CDS YP_032017.1 49473975 2866458 complement(411427..412359) 1 NC_005955.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 412359 prsA 2866458 prsA Bartonella quintana str. Toulouse ribose-phosphate pyrophosphokinase YP_032017.1 411427 R 283165 CDS YP_032018.1 49473976 2866404 complement(413242..414033) 1 NC_005955.1 hypothetical protein 414033 2866404 BQ03320 Bartonella quintana str. Toulouse hypothetical protein YP_032018.1 413242 R 283165 CDS YP_032019.1 49473977 2866430 complement(414101..415192) 1 NC_005955.1 hypothetical protein 415192 2866430 BQ03330 Bartonella quintana str. Toulouse hypothetical protein YP_032019.1 414101 R 283165 CDS YP_032020.1 49473978 2867557 complement(415167..416045) 1 NC_005955.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 416045 lgt 2867557 lgt Bartonella quintana str. Toulouse prolipoprotein diacylglyceryl transferase YP_032020.1 415167 R 283165 CDS YP_032021.1 49473979 2866403 416308..416565 1 NC_005955.1 hypothetical protein 416565 2866403 BQ03350 Bartonella quintana str. Toulouse hypothetical protein YP_032021.1 416308 D 283165 CDS YP_032022.1 49473980 2867603 416766..416996 1 NC_005955.1 hypothetical protein 416996 2867603 BQ03360 Bartonella quintana str. Toulouse hypothetical protein YP_032022.1 416766 D 283165 CDS YP_032023.1 49473981 2866406 416950..417450 1 NC_005955.1 hypothetical protein 417450 2866406 BQ03370 Bartonella quintana str. Toulouse hypothetical protein YP_032023.1 416950 D 283165 CDS YP_032024.1 49473982 2866706 complement(417503..418843) 1 NC_005955.1 sensor histidine kinase 418843 envZ 2866706 envZ Bartonella quintana str. Toulouse sensor histidine kinase YP_032024.1 417503 R 283165 CDS YP_032025.1 49473983 2867573 complement(418851..419555) 1 NC_005955.1 transcriptional regulator ompR 419555 ompR 2867573 ompR Bartonella quintana str. Toulouse transcriptional regulator ompR YP_032025.1 418851 R 283165 CDS YP_032026.1 49473984 2867162 419695..420348 1 NC_005955.1 hypothetical protein 420348 2867162 BQ03400 Bartonella quintana str. Toulouse hypothetical protein YP_032026.1 419695 D 283165 CDS YP_032027.1 49473985 2867134 complement(420423..421136) 1 NC_005955.1 hypothetical protein 421136 2867134 BQ03410 Bartonella quintana str. Toulouse hypothetical protein YP_032027.1 420423 R 283165 CDS YP_032028.1 49473986 2866531 422818..423489 1 NC_005955.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 423489 rnhB 2866531 rnhB Bartonella quintana str. Toulouse ribonuclease HII YP_032028.1 422818 D 283165 CDS YP_032029.1 49473987 2867584 423486..424448 1 NC_005955.1 hypothetical protein 424448 2867584 BQ03430 Bartonella quintana str. Toulouse hypothetical protein YP_032029.1 423486 D 283165 CDS YP_032030.1 49473988 2867133 424451..425860 1 NC_005955.1 oxidoreductase 425860 2867133 BQ03440 Bartonella quintana str. Toulouse oxidoreductase YP_032030.1 424451 D 283165 CDS YP_032031.1 49473989 2867212 426010..426534 1 NC_005955.1 hypothetical protein 426534 2867212 BQ03450 Bartonella quintana str. Toulouse hypothetical protein YP_032031.1 426010 D 283165 CDS YP_032032.1 49473990 2866817 complement(427142..428416) 1 NC_005955.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 428416 purD 2866817 purD Bartonella quintana str. Toulouse phosphoribosylamine--glycine ligase YP_032032.1 427142 R 283165 CDS YP_032033.1 49473991 2866528 428508..429512 1 NC_005955.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 429512 ubiA 2866528 ubiA Bartonella quintana str. Toulouse 4-hydroxybenzoate polyprenyltransferase YP_032033.1 428508 D 283165 CDS YP_032034.1 49473992 2867056 complement(430033..430656) 1 NC_005955.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 430656 pdxH 2867056 pdxH Bartonella quintana str. Toulouse pyridoxamine 5'-phosphate oxidase YP_032034.1 430033 R 283165 CDS YP_032035.1 49473993 2866750 430980..431882 1 NC_005955.1 molecular chaperone DnaJ 431882 dnaJ2 2866750 dnaJ2 Bartonella quintana str. Toulouse molecular chaperone DnaJ YP_032035.1 430980 D 283165 CDS YP_032036.1 49473994 2867028 432003..432821 1 NC_005955.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 432821 fabI2 2867028 fabI2 Bartonella quintana str. Toulouse enoyl-ACP reductase YP_032036.1 432003 D 283165 CDS YP_032037.1 49473995 2867196 432967..434067 1 NC_005955.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 434067 aroC 2867196 aroC Bartonella quintana str. Toulouse chorismate synthase YP_032037.1 432967 D 283165 CDS YP_032038.1 49473996 2867512 434071..435177 1 NC_005955.1 GTP cyclohydrolase II 435177 ribA 2867512 ribA Bartonella quintana str. Toulouse GTP cyclohydrolase II YP_032038.1 434071 D 283165 CDS YP_032039.1 49473997 2866901 435185..435439 1 NC_005955.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 435439 xseB 2866901 xseB Bartonella quintana str. Toulouse exodeoxyribonuclease VII small subunit YP_032039.1 435185 D 283165 CDS YP_032040.1 49473998 2866512 435670..437592 1 NC_005955.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 437592 dxs 2866512 dxs Bartonella quintana str. Toulouse 1-deoxy-D-xylulose-5-phosphate synthase YP_032040.1 435670 D 283165 CDS YP_032041.1 49473999 2867214 437704..438237 1 NC_005955.1 hemolysin-like protein 438237 tlyA 2867214 tlyA Bartonella quintana str. Toulouse hemolysin-like protein YP_032041.1 437704 D 283165 CDS YP_032042.1 49474000 2867445 complement(440577..441995) 1 NC_005955.1 tldD protein 441995 tldD 2867445 tldD Bartonella quintana str. Toulouse tldD protein YP_032042.1 440577 R 283165 CDS YP_032043.1 49474001 2866768 complement(442097..442636) 1 NC_005955.1 hypothetical protein 442636 2866768 BQ03580 Bartonella quintana str. Toulouse hypothetical protein YP_032043.1 442097 R 283165 CDS YP_032044.1 49474002 2867423 443031..443966 1 NC_005955.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 443966 cyoE 2867423 cyoE Bartonella quintana str. Toulouse protoheme IX farnesyltransferase YP_032044.1 443031 D 283165 CDS YP_032045.1 49474003 2866542 444150..445172 1 NC_005955.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 445172 ispH 2866542 ispH Bartonella quintana str. Toulouse 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_032045.1 444150 D 283165 CDS YP_032046.1 49474004 2867210 446165..446632 1 NC_005955.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 446632 rnhA 2867210 rnhA Bartonella quintana str. Toulouse ribonuclease H YP_032046.1 446165 D 283165 CDS YP_032047.1 49474005 2866679 447611..448195 1 NC_005955.1 hypothetical protein 448195 2866679 BQ03640 Bartonella quintana str. Toulouse hypothetical protein YP_032047.1 447611 D 283165 CDS YP_032048.1 49474006 2867328 complement(448243..451128) 1 NC_005955.1 hypothetical protein 451128 2867328 BQ03650 Bartonella quintana str. Toulouse hypothetical protein YP_032048.1 448243 R 283165 CDS YP_032049.1 49474007 2866549 complement(451580..452854) 1 NC_005955.1 processing protease 452854 2866549 BQ03660 Bartonella quintana str. Toulouse processing protease YP_032049.1 451580 R 283165 CDS YP_032050.1 49474008 2867218 complement(454760..455125) 1 NC_005955.1 hypothetical protein 455125 2867218 BQ03680 Bartonella quintana str. Toulouse hypothetical protein YP_032050.1 454760 R 283165 CDS YP_032051.1 49474009 2867205 complement(455368..455730) 1 NC_005955.1 hypothetical protein 455730 2867205 BQ03690 Bartonella quintana str. Toulouse hypothetical protein YP_032051.1 455368 R 283165 CDS YP_032052.1 49474010 2866417 complement(455924..456271) 1 NC_005955.1 hypothetical protein 456271 2866417 BQ03700 Bartonella quintana str. Toulouse hypothetical protein YP_032052.1 455924 R 283165 CDS YP_032053.1 49474011 2867280 complement(457330..458025) 1 NC_005955.1 phosphatase 458025 2867280 BQ03710 Bartonella quintana str. Toulouse phosphatase YP_032053.1 457330 R 283165 CDS YP_032054.1 49474012 2867431 458386..459522 1 NC_005955.1 adenine DNA methyltransferase 459522 ccrM 2867431 ccrM Bartonella quintana str. Toulouse adenine DNA methyltransferase YP_032054.1 458386 D 283165 CDS YP_032055.1 49474013 2867271 complement(459575..460681) 1 NC_005955.1 A/G-specific adenine glycosylase 460681 mutY 2867271 mutY Bartonella quintana str. Toulouse A/G-specific adenine glycosylase YP_032055.1 459575 R 283165 CDS YP_032056.1 49474014 2867534 460841..461341 1 NC_005955.1 hypothetical protein 461341 2867534 BQ03740 Bartonella quintana str. Toulouse hypothetical protein YP_032056.1 460841 D 283165 CDS YP_032057.1 49474015 2867378 461424..462080 1 NC_005955.1 hypothetical protein 462080 2867378 BQ03750 Bartonella quintana str. Toulouse hypothetical protein YP_032057.1 461424 D 283165 CDS YP_032058.1 49474016 2867373 462262..464928 1 NC_005955.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 464928 ppdK 2867373 ppdK Bartonella quintana str. Toulouse pyruvate phosphate dikinase YP_032058.1 462262 D 283165 CDS YP_032059.1 49474017 2866433 complement(465149..465991) 1 NC_005955.1 hypothetical protein 465991 2866433 BQ03770 Bartonella quintana str. Toulouse hypothetical protein YP_032059.1 465149 R 283165 CDS YP_032060.1 49474018 2867370 467783..468160 1 NC_005955.1 hypothetical protein 468160 2867370 BQ03780 Bartonella quintana str. Toulouse hypothetical protein YP_032060.1 467783 D 283165 CDS YP_032061.1 49474019 2866309 468272..468682 1 NC_005955.1 hypothetical protein 468682 2866309 BQ03790 Bartonella quintana str. Toulouse hypothetical protein YP_032061.1 468272 D 283165 CDS YP_032062.1 49474020 2866318 complement(468783..469220) 1 NC_005955.1 Ros/MucR family transcriptional regulator 469220 2866318 BQ03800 Bartonella quintana str. Toulouse Ros/MucR family transcriptional regulator YP_032062.1 468783 R 283165 CDS YP_032063.1 49474021 2866838 470113..472206 1 NC_005955.1 oligopeptidase B 472206 ptrB 2866838 ptrB Bartonella quintana str. Toulouse oligopeptidase B YP_032063.1 470113 D 283165 CDS YP_032064.1 49474022 2866982 complement(472301..472903) 1 NC_005955.1 superoxide dismutase 472903 sodB 2866982 sodB Bartonella quintana str. Toulouse superoxide dismutase YP_032064.1 472301 R 283165 CDS YP_032065.1 49474023 2866336 complement(474308..475375) 1 NC_005955.1 toxin secretion protein 475375 2866336 BQ03850 Bartonella quintana str. Toulouse toxin secretion protein YP_032065.1 474308 R 283165 CDS YP_032066.1 49474024 2866752 complement(476818..477603) 1 NC_005955.1 hypothetical protein 477603 2866752 BQ03860 Bartonella quintana str. Toulouse hypothetical protein YP_032066.1 476818 R 283165 CDS YP_032067.1 49474025 2866557 complement(478214..478753) 1 NC_005955.1 hypothetical protein 478753 2866557 BQ03870 Bartonella quintana str. Toulouse hypothetical protein YP_032067.1 478214 R 283165 CDS YP_032068.1 49474026 2867235 complement(478746..479342) 1 NC_005955.1 hypothetical protein 479342 2867235 BQ03880 Bartonella quintana str. Toulouse hypothetical protein YP_032068.1 478746 R 283165 CDS YP_032069.1 49474027 2866622 complement(479360..481510) 1 NC_005955.1 penicillin-binding protein mrcA 481510 mrcA1 2866622 mrcA1 Bartonella quintana str. Toulouse penicillin-binding protein mrcA YP_032069.1 479360 R 283165 CDS YP_032070.1 49474028 2867136 481835..482113 1 NC_005955.1 hypothetical protein 482113 2867136 BQ03900 Bartonella quintana str. Toulouse hypothetical protein YP_032070.1 481835 D 283165 CDS YP_032071.1 49474029 2867393 482132..482800 1 NC_005955.1 two-component system regulatory protein 482800 feuP 2867393 feuP Bartonella quintana str. Toulouse two-component system regulatory protein YP_032071.1 482132 D 283165 CDS YP_032072.1 49474030 2867392 482797..484221 1 NC_005955.1 sensor histidine kinase 484221 feuQ 2867392 feuQ Bartonella quintana str. Toulouse sensor histidine kinase YP_032072.1 482797 D 283165 CDS YP_032073.1 49474031 2867084 484488..485225 1 NC_005955.1 cytochrome c-type biogenesis protein cycH 485225 cycH 2867084 cycH Bartonella quintana str. Toulouse cytochrome c-type biogenesis protein cycH YP_032073.1 484488 D 283165 CDS YP_032074.1 49474032 2867365 485594..486073 1 NC_005955.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 486073 cycJ 2867365 cycJ Bartonella quintana str. Toulouse cytochrome c-type biogenesis protein CcmE YP_032074.1 485594 D 283165 CDS YP_032075.1 49474033 2867366 486081..488069 1 NC_005955.1 cytochrome c-type biogenesis protein cycK 488069 cycK 2867366 cycK Bartonella quintana str. Toulouse cytochrome c-type biogenesis protein cycK YP_032075.1 486081 D 283165 CDS YP_032076.1 49474034 2867024 488066..488518 1 NC_005955.1 cytochrome c-type biogenesis protein cycL 488518 cycL 2867024 cycL Bartonella quintana str. Toulouse cytochrome c-type biogenesis protein cycL YP_032076.1 488066 D 283165 CDS YP_032077.1 49474035 2867471 488703..490214 1 NC_005955.1 Serine protease 490214 htrA1 2867471 htrA1 Bartonella quintana str. Toulouse Serine protease YP_032077.1 488703 D 283165 CDS YP_032078.1 49474036 2867610 490295..490981 1 NC_005955.1 two-component response regulator 490981 2867610 BQ03980 Bartonella quintana str. Toulouse two-component response regulator YP_032078.1 490295 D 283165 CDS YP_032079.1 49474037 2866400 490978..492360 1 NC_005955.1 sensor histidine kinase 492360 2866400 BQ03990 Bartonella quintana str. Toulouse sensor histidine kinase YP_032079.1 490978 D 283165 CDS YP_032080.1 49474038 2866297 492488..495412 1 NC_005955.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 495412 glnE 2866297 glnE Bartonella quintana str. Toulouse bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_032080.1 492488 D 283165 CDS YP_032081.1 49474039 2866271 496452..497336 1 NC_005955.1 hemin binding protein d 497336 hbpD 2866271 hbpD Bartonella quintana str. Toulouse hemin binding protein d YP_032081.1 496452 D 283165 CDS YP_032082.1 49474040 2866444 497734..498258 1 NC_005955.1 methyltransferase (fragment) 498258 2866444 BQ04020 Bartonella quintana str. Toulouse methyltransferase (fragment) YP_032082.1 497734 D 283165 CDS YP_032083.1 49474041 2866427 complement(498266..500587) 1 NC_005955.1 two-component sensor histidine kinase 500587 2866427 BQ04030 Bartonella quintana str. Toulouse two-component sensor histidine kinase YP_032083.1 498266 R 283165 CDS YP_032084.1 49474042 2866957 complement(500873..503503) 1 NC_005955.1 aminopeptidase 503503 pepN 2866957 pepN Bartonella quintana str. Toulouse aminopeptidase YP_032084.1 500873 R 283165 CDS YP_032085.1 49474043 2866550 complement(503583..504410) 1 NC_005955.1 DNA polymerase 504410 2866550 BQ04050 Bartonella quintana str. Toulouse DNA polymerase YP_032085.1 503583 R 283165 CDS YP_032086.1 49474044 2867305 complement(505396..506142) 1 NC_005955.1 phosphomethylpyrimidine kinase 506142 thiD1 2867305 thiD1 Bartonella quintana str. Toulouse phosphomethylpyrimidine kinase YP_032086.1 505396 R 283165 CDS YP_032087.1 49474045 2867299 complement(506133..506738) 1 NC_005955.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 506738 thiE 2867299 thiE Bartonella quintana str. Toulouse thiamine-phosphate pyrophosphorylase YP_032087.1 506133 R 283165 CDS YP_032088.1 49474046 2866582 complement(506735..507508) 1 NC_005955.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 507508 thiG 2866582 thiG Bartonella quintana str. Toulouse thiazole synthase YP_032088.1 506735 R 283165 CDS YP_032089.1 49474047 2866830 complement(507513..507710) 1 NC_005955.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 507710 thiG1 2866830 thiG1 Bartonella quintana str. Toulouse sulfur carrier protein ThiS YP_032089.1 507513 R 283165 CDS YP_032090.1 49474048 2866831 complement(507714..508664) 1 NC_005955.1 thiamine biosynthesis oxidoreductase 508664 thiO 2866831 thiO Bartonella quintana str. Toulouse thiamine biosynthesis oxidoreductase YP_032090.1 507714 R 283165 CDS YP_032091.1 49474049 2867532 complement(508745..510511) 1 NC_005955.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 510511 thiC 2867532 thiC Bartonella quintana str. Toulouse thiamine biosynthesis protein ThiC YP_032091.1 508745 R 283165 CDS YP_032092.1 49474050 2867303 complement(511572..512366) 1 NC_005955.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 512366 hmuV 2867303 hmuV Bartonella quintana str. Toulouse hemin importer ATP-binding subunit YP_032092.1 511572 R 283165 CDS YP_032093.1 49474051 2866873 complement(512363..513460) 1 NC_005955.1 hemin ABC transporter permease 513460 hutC 2866873 hutC Bartonella quintana str. Toulouse hemin ABC transporter permease YP_032093.1 512363 R 283165 CDS YP_032094.1 49474052 2866866 complement(513465..514367) 1 NC_005955.1 periplasmic hemin-binding protein 514367 hutB 2866866 hutB Bartonella quintana str. Toulouse periplasmic hemin-binding protein YP_032094.1 513465 R 283165 CDS YP_032095.1 49474053 2866418 complement(514401..515426) 1 NC_005955.1 hemin degrading protein 515426 hemS 2866418 hemS Bartonella quintana str. Toulouse hemin degrading protein YP_032095.1 514401 R 283165 CDS YP_032096.1 49474054 2866826 complement(515687..517864) 1 NC_005955.1 Heme receptor precursor 517864 hutA 2866826 hutA Bartonella quintana str. Toulouse Heme receptor precursor YP_032096.1 515687 R 283165 CDS YP_032097.1 49474055 2866473 518104..518883 1 NC_005955.1 tonB protein 518883 tonB 2866473 tonB Bartonella quintana str. Toulouse tonB protein YP_032097.1 518104 D 283165 CDS YP_032098.1 49474056 2867010 complement(518997..521090) 1 NC_005955.1 soluble lytic murein transglycosylase precursor 521090 slt 2867010 slt Bartonella quintana str. Toulouse soluble lytic murein transglycosylase precursor YP_032098.1 518997 R 283165 CDS YP_032099.1 49474057 2867248 521337..522221 1 NC_005955.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 522221 dapA 2867248 dapA Bartonella quintana str. Toulouse dihydrodipicolinate synthase YP_032099.1 521337 D 283165 CDS YP_032100.1 49474058 2866981 522239..522715 1 NC_005955.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 522715 smpB 2866981 smpB Bartonella quintana str. Toulouse SsrA-binding protein YP_032100.1 522239 D 283165 CDS YP_032101.1 49474059 2866753 complement(522763..523431) 1 NC_005955.1 hypothetical protein 523431 2866753 BQ04210 Bartonella quintana str. Toulouse hypothetical protein YP_032101.1 522763 R 283165 CDS YP_032102.1 49474060 2867319 523988..524386 1 NC_005955.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 524386 rpoZ 2867319 rpoZ Bartonella quintana str. Toulouse DNA-directed RNA polymerase subunit omega YP_032102.1 523988 D 283165 CDS YP_032103.1 49474061 2866361 524538..526766 1 NC_005955.1 GTP pyrophosphokinase 526766 spoT 2866361 spoT Bartonella quintana str. Toulouse GTP pyrophosphokinase YP_032103.1 524538 D 283165 CDS YP_032104.1 49474062 2866815 526784..527362 1 NC_005955.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 527362 pyrE 2866815 pyrE Bartonella quintana str. Toulouse orotate phosphoribosyltransferase YP_032104.1 526784 D 283165 CDS YP_032105.1 49474063 2867211 527461..528039 1 NC_005955.1 hypothetical protein 528039 2867211 BQ04250 Bartonella quintana str. Toulouse hypothetical protein YP_032105.1 527461 D 283165 CDS YP_032106.1 49474064 2866794 528060..528461 1 NC_005955.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 528461 acpS 2866794 acpS Bartonella quintana str. Toulouse 4'-phosphopantetheinyl transferase YP_032106.1 528060 D 283165 CDS YP_032107.1 49474065 2867563 528542..529354 1 NC_005955.1 Signal peptidase I 529354 lebB 2867563 lebB Bartonella quintana str. Toulouse Signal peptidase I YP_032107.1 528542 D 283165 CDS YP_032108.2 161761284 2867232 529302..530042 1 NC_005955.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 530042 rncS 2867232 rncS Bartonella quintana str. Toulouse ribonuclease III YP_032108.2 529302 D 283165 CDS YP_032109.1 49474067 2866854 530035..530940 1 NC_005955.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 530940 era 2866854 era Bartonella quintana str. Toulouse GTP-binding protein Era YP_032109.1 530035 D 283165 CDS YP_032110.1 49474068 2867130 530942..531673 1 NC_005955.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 531673 recO 2867130 recO Bartonella quintana str. Toulouse DNA repair protein RecO YP_032110.1 530942 D 283165 CDS YP_032111.1 49474069 2867251 531710..532570 1 NC_005955.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 532570 panC 2867251 panC Bartonella quintana str. Toulouse pantoate--beta-alanine ligase YP_032111.1 531710 D 283165 CDS YP_032112.1 49474070 2867164 532574..533401 1 NC_005955.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 533401 panB 2867164 panB Bartonella quintana str. Toulouse 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_032112.1 532574 D 283165 CDS YP_032113.1 49474071 2867139 complement(534768..535388) 1 NC_005955.1 hypothetical protein 535388 2867139 BQ04330 Bartonella quintana str. Toulouse hypothetical protein YP_032113.1 534768 R 283165 CDS YP_032114.1 49474072 2867117 complement(535388..536254) 1 NC_005955.1 hypothetical protein 536254 2867117 BQ04340 Bartonella quintana str. Toulouse hypothetical protein YP_032114.1 535388 R 283165 CDS YP_032115.1 49474073 2867066 536320..537648 1 NC_005955.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 537648 pyrC1 2867066 pyrC1 Bartonella quintana str. Toulouse dihydroorotase YP_032115.1 536320 D 283165 CDS YP_032116.1 49474074 2867245 complement(537868..538239) 1 NC_005955.1 hypothetical protein 538239 2867245 BQ04360 Bartonella quintana str. Toulouse hypothetical protein YP_032116.1 537868 R 283165 CDS YP_032117.1 49474075 2867427 538709..540217 1 NC_005955.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 540217 cysS 2867427 cysS Bartonella quintana str. Toulouse cysteinyl-tRNA synthetase YP_032117.1 538709 D 283165 CDS YP_032118.1 49474076 2866909 540261..540932 1 NC_005955.1 hypothetical protein 540932 2866909 BQ04380 Bartonella quintana str. Toulouse hypothetical protein YP_032118.1 540261 D 283165 CDS YP_032119.1 49474077 2866899 541048..542931 1 NC_005955.1 ABC transporter ATP-binding protein 542931 2866899 BQ04390 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032119.1 541048 D 283165 CDS YP_032120.1 49474078 2866459 543053..543754 1 NC_005955.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 543754 psdA 2866459 psdA Bartonella quintana str. Toulouse phosphatidylserine decarboxylase YP_032120.1 543053 D 283165 CDS YP_032121.1 49474079 2866626 543763..544602 1 NC_005955.1 phosphatidylserine synthase 544602 pssA 2866626 pssA Bartonella quintana str. Toulouse phosphatidylserine synthase YP_032121.1 543763 D 283165 CDS YP_032122.1 49474080 2867386 complement(544675..545424) 1 NC_005955.1 oxidoreductase 545424 2867386 BQ04420 Bartonella quintana str. Toulouse oxidoreductase YP_032122.1 544675 R 283165 CDS YP_032123.1 49474081 2867073 complement(545428..546960) 1 NC_005955.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 546960 purF 2867073 purF Bartonella quintana str. Toulouse amidophosphoribosyltransferase YP_032123.1 545428 R 283165 CDS YP_032124.1 49474082 2866859 complement(547010..547579) 1 NC_005955.1 colicin v production protein 547579 cvpA 2866859 cvpA Bartonella quintana str. Toulouse colicin v production protein YP_032124.1 547010 R 283165 CDS YP_032125.1 49474083 2866267 complement(547704..549098) 1 NC_005955.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 549098 radA 2866267 radA Bartonella quintana str. Toulouse DNA repair protein RadA YP_032125.1 547704 R 283165 CDS YP_032126.1 49474084 2866821 complement(549105..550607) 1 NC_005955.1 unwinds double stranded DNA; replicative DNA helicase 550607 dnaB 2866821 dnaB Bartonella quintana str. Toulouse replicative DNA helicase YP_032126.1 549105 R 283165 CDS YP_032127.1 49474085 2866742 complement(551260..551841) 1 NC_005955.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 551841 rplI 2866742 rplI Bartonella quintana str. Toulouse 50S ribosomal protein L9 YP_032127.1 551260 R 283165 CDS YP_032128.1 49474086 2866860 complement(551866..552846) 1 NC_005955.1 hypothetical protein 552846 2866860 BQ04480 Bartonella quintana str. Toulouse hypothetical protein YP_032128.1 551866 R 283165 CDS YP_032129.1 49474087 2867379 complement(553000..553248) 1 NC_005955.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 553248 rpsR 2867379 rpsR Bartonella quintana str. Toulouse 30S ribosomal protein S18 YP_032129.1 553000 R 283165 CDS YP_032130.1 49474088 2867309 complement(553245..553655) 1 NC_005955.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 553655 rpsF 2867309 rpsF Bartonella quintana str. Toulouse 30S ribosomal protein S6 YP_032130.1 553245 R 283165 CDS YP_032131.1 49474089 2866294 554006..554593 1 NC_005955.1 hypothetical protein 554593 2866294 BQ04510 Bartonella quintana str. Toulouse hypothetical protein YP_032131.1 554006 D 283165 CDS YP_032132.1 49474090 2867021 554670..555614 1 NC_005955.1 ACP S-malonyltransferase 555614 fabD 2867021 fabD Bartonella quintana str. Toulouse ACP S-malonyltransferase YP_032132.1 554670 D 283165 CDS YP_032133.1 49474091 2867025 555634..556371 1 NC_005955.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 556371 fabG 2867025 fabG Bartonella quintana str. Toulouse 3-ketoacyl-ACP reductase YP_032133.1 555634 D 283165 CDS YP_032134.1 49474092 2867229 556634..556870 1 NC_005955.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 556870 acpP 2867229 acpP Bartonella quintana str. Toulouse acyl carrier protein YP_032134.1 556634 D 283165 CDS YP_032135.1 49474093 2867018 556980..558242 1 NC_005955.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 558242 fabF1 2867018 fabF1 Bartonella quintana str. Toulouse 3-oxoacyl-ACP synthase YP_032135.1 556980 D 283165 CDS YP_032136.1 49474094 2866274 558345..559454 1 NC_005955.1 hypothetical protein 559454 2866274 BQ04560 Bartonella quintana str. Toulouse hypothetical protein YP_032136.1 558345 D 283165 CDS YP_032137.1 49474095 2866824 559524..560189 1 NC_005955.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 560189 gmk 2866824 gmk Bartonella quintana str. Toulouse guanylate kinase YP_032137.1 559524 D 283165 CDS YP_032138.1 49474096 2867111 complement(560238..561068) 1 NC_005955.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 561068 ksgA 2867111 ksgA Bartonella quintana str. Toulouse dimethyladenosine transferase YP_032138.1 560238 R 283165 CDS YP_032139.1 49474097 2866868 complement(561059..562072) 1 NC_005955.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 562072 pdxA 2866868 pdxA Bartonella quintana str. Toulouse 4-hydroxythreonine-4-phosphate dehydrogenase YP_032139.1 561059 R 283165 CDS YP_032140.1 49474098 2866279 complement(562072..563046) 1 NC_005955.1 hypothetical protein 563046 2866279 BQ04600 Bartonella quintana str. Toulouse hypothetical protein YP_032140.1 562072 R 283165 CDS YP_032141.1 49474099 2867556 complement(563132..565504) 1 NC_005955.1 hypothetical protein 565504 2867556 BQ04610 Bartonella quintana str. Toulouse hypothetical protein YP_032141.1 563132 R 283165 CDS YP_032142.1 49474100 2866347 complement(565505..566599) 1 NC_005955.1 hypothetical protein 566599 2866347 BQ04620 Bartonella quintana str. Toulouse hypothetical protein YP_032142.1 565505 R 283165 CDS YP_032143.1 49474101 2866561 complement(566596..567786) 1 NC_005955.1 hypothetical protein 567786 2866561 BQ04630 Bartonella quintana str. Toulouse hypothetical protein YP_032143.1 566596 R 283165 CDS YP_032144.1 49474102 2867560 568177..568638 1 NC_005955.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 568638 2867560 BQ04640 Bartonella quintana str. Toulouse DNA polymerase III subunit chi YP_032144.1 568177 D 283165 CDS YP_032145.1 49474103 2867119 568829..569092 1 NC_005955.1 hypothetical protein 569092 2867119 BQ04650 Bartonella quintana str. Toulouse hypothetical protein YP_032145.1 568829 D 283165 CDS YP_032146.1 49474104 2867372 complement(569089..570408) 1 NC_005955.1 transport protein 570408 yhjE 2867372 yhjE Bartonella quintana str. Toulouse transport protein YP_032146.1 569089 R 283165 CDS YP_032147.1 49474105 2866304 571342..573933 1 NC_005955.1 hypothetical protein 573933 2866304 BQ04680 Bartonella quintana str. Toulouse hypothetical protein YP_032147.1 571342 D 283165 CDS YP_032148.1 49474106 2866307 574324..574746 1 NC_005955.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 574746 ndk 2866307 ndk Bartonella quintana str. Toulouse nucleoside diphosphate kinase YP_032148.1 574324 D 283165 CDS YP_032149.1 49474107 2866283 complement(574851..575432) 1 NC_005955.1 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase 575432 pgsA 2866283 pgsA Bartonella quintana str. Toulouse CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase YP_032149.1 574851 R 283165 CDS YP_032150.1 49474108 2867327 complement(575507..577543) 1 NC_005955.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 577543 uvrC 2867327 uvrC Bartonella quintana str. Toulouse excinuclease ABC subunit C YP_032150.1 575507 R 283165 CDS YP_032151.1 49474109 2866407 complement(577943..578785) 1 NC_005955.1 hypothetical protein 578785 2866407 BQ04720 Bartonella quintana str. Toulouse hypothetical protein YP_032151.1 577943 R 283165 CDS YP_032152.1 49474110 2866881 580782..581093 1 NC_005955.1 hypothetical protein 581093 tatA 2866881 tatA Bartonella quintana str. Toulouse hypothetical protein YP_032152.1 580782 D 283165 CDS YP_032153.1 49474111 2866882 581159..581599 1 NC_005955.1 hypothetical protein 581599 tatB 2866882 tatB Bartonella quintana str. Toulouse hypothetical protein YP_032153.1 581159 D 283165 CDS YP_032154.1 49474112 2867333 581596..582387 1 NC_005955.1 Sec-independent protein translocase component 582387 tatC 2867333 tatC Bartonella quintana str. Toulouse Sec-independent protein translocase component YP_032154.1 581596 D 283165 CDS YP_032155.1 49474113 2866326 582435..583712 1 NC_005955.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 583712 serS 2866326 serS Bartonella quintana str. Toulouse seryl-tRNA synthetase YP_032155.1 582435 D 283165 CDS YP_032156.1 49474114 2867542 583846..584505 1 NC_005955.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 584505 pcm 2867542 pcm Bartonella quintana str. Toulouse protein-L-isoaspartate O-methyltransferase YP_032156.1 583846 D 283165 CDS YP_032157.1 49474115 2866435 584674..585849 1 NC_005955.1 antigen (virulence determinant) (lipoptrotein) 585849 2866435 BQ04790 Bartonella quintana str. Toulouse antigen (virulence determinant) (lipoptrotein) YP_032157.1 584674 D 283165 CDS YP_032158.1 49474116 2866291 586249..586701 1 NC_005955.1 hypothetical protein 586701 2866291 BQ04800 Bartonella quintana str. Toulouse hypothetical protein YP_032158.1 586249 D 283165 CDS YP_032159.1 49474117 2866311 587227..587613 1 NC_005955.1 hypothetical protein 587613 2866311 BQ04810 Bartonella quintana str. Toulouse hypothetical protein YP_032159.1 587227 D 283165 CDS YP_032160.1 49474118 2866842 587610..588470 1 NC_005955.1 hypothetical protein 588470 2866842 BQ04820 Bartonella quintana str. Toulouse hypothetical protein YP_032160.1 587610 D 283165 CDS YP_032161.1 49474119 2867297 complement(589164..591053) 1 NC_005955.1 peptidyl-prolyl cis-trans isomerase 591053 ppiD 2867297 ppiD Bartonella quintana str. Toulouse peptidyl-prolyl cis-trans isomerase YP_032161.1 589164 R 283165 CDS YP_032162.1 49474120 2866611 591207..591971 1 NC_005955.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 591971 tpiA 2866611 tpiA Bartonella quintana str. Toulouse triosephosphate isomerase YP_032162.1 591207 D 283165 CDS YP_032163.1 49474121 2866454 592053..592508 1 NC_005955.1 preprotein translocase subunit SecG 592508 secG 2866454 secG Bartonella quintana str. Toulouse preprotein translocase subunit SecG YP_032163.1 592053 D 283165 CDS YP_032164.1 49474122 2867350 592636..594264 1 NC_005955.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 594264 pyrG 2867350 pyrG Bartonella quintana str. Toulouse CTP synthetase YP_032164.1 592636 D 283165 CDS YP_032165.1 49474123 2866392 594301..595137 1 NC_005955.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 595137 kdsA 2866392 kdsA Bartonella quintana str. Toulouse 2-dehydro-3-deoxyphosphooctonate aldolase YP_032165.1 594301 D 283165 CDS YP_032166.1 49474124 2866707 595210..596478 1 NC_005955.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 596478 eno 2866707 eno Bartonella quintana str. Toulouse phosphopyruvate hydratase YP_032166.1 595210 D 283165 CDS YP_032167.1 49474125 2866342 596587..596991 1 NC_005955.1 hypothetical protein 596991 2866342 BQ04890 Bartonella quintana str. Toulouse hypothetical protein YP_032167.1 596587 D 283165 CDS YP_032168.1 49474126 2867100 597188..597517 1 NC_005955.1 hypothetical protein 597517 2867100 BQ04900 Bartonella quintana str. Toulouse hypothetical protein YP_032168.1 597188 D 283165 CDS YP_032169.1 49474127 2866532 597646..598686 1 NC_005955.1 pyruvate dehydrogenase E1 component, alpha subunit 598686 pdhA 2866532 pdhA Bartonella quintana str. Toulouse pyruvate dehydrogenase E1 component, alpha subunit YP_032169.1 597646 D 283165 CDS YP_032170.1 49474128 2866533 598703..600067 1 NC_005955.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 600067 pdhB 2866533 pdhB Bartonella quintana str. Toulouse pyruvate dehydrogenase subunit beta YP_032170.1 598703 D 283165 CDS YP_032171.1 49474129 2866740 600082..601401 1 NC_005955.1 branched-chain alpha-keto acid dehydrogenase subunit E2 601401 pdhC 2866740 pdhC Bartonella quintana str. Toulouse branched-chain alpha-keto acid dehydrogenase subunit E2 YP_032171.1 600082 D 283165 CDS YP_032172.1 49474130 2866574 601625..603085 1 NC_005955.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 603085 pdhD2 2866574 pdhD2 Bartonella quintana str. Toulouse dihydrolipoamide dehydrogenase YP_032172.1 601625 D 283165 CDS YP_032173.1 49474131 2866312 603161..604123 1 NC_005955.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 604123 lipA 2866312 lipA Bartonella quintana str. Toulouse lipoyl synthase YP_032173.1 603161 D 283165 CDS YP_032174.1 49474132 2866302 604126..604587 1 NC_005955.1 hypothetical protein 604587 2866302 BQ04960 Bartonella quintana str. Toulouse hypothetical protein YP_032174.1 604126 D 283165 CDS YP_032175.1 49474133 2866535 complement(604686..605174) 1 NC_005955.1 competence /damage-inducible protein cinA 605174 cinA 2866535 cinA Bartonella quintana str. Toulouse competence /damage-inducible protein cinA YP_032175.1 604686 R 283165 CDS YP_032176.1 49474134 2866390 complement(605171..606346) 1 NC_005955.1 IspD/ispF bifunctional enzyme 606346 ispDF 2866390 ispDF Bartonella quintana str. Toulouse IspD/ispF bifunctional enzyme YP_032176.1 605171 R 283165 CDS YP_032177.1 49474135 2866299 complement(606412..606858) 1 NC_005955.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 606858 rirA 2866299 rirA Bartonella quintana str. Toulouse iron-responsive transcriptional regulator YP_032177.1 606412 R 283165 CDS YP_032178.1 49474136 2866545 607036..609300 1 NC_005955.1 nitrogen regulation protein 609300 ntrY 2866545 ntrY Bartonella quintana str. Toulouse nitrogen regulation protein YP_032178.1 607036 D 283165 CDS YP_032179.1 49474137 2867107 609302..610660 1 NC_005955.1 nitrogen regulation protein 610660 ntrX 2867107 ntrX Bartonella quintana str. Toulouse nitrogen regulation protein YP_032179.1 609302 D 283165 CDS YP_032180.1 49474138 2866486 610664..612040 1 NC_005955.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 612040 trkA 2866486 trkA Bartonella quintana str. Toulouse potassium transporter peripheral membrane component YP_032180.1 610664 D 283165 CDS YP_032181.1 49474139 2866461 613016..613648 1 NC_005955.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 613648 clpP 2866461 clpP Bartonella quintana str. Toulouse ATP-dependent Clp protease proteolytic subunit YP_032181.1 613016 D 283165 CDS YP_032182.1 49474140 2866674 613835..615109 1 NC_005955.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 615109 clpX 2866674 clpX Bartonella quintana str. Toulouse ATP-dependent protease ATP-binding subunit ClpX YP_032182.1 613835 D 283165 CDS YP_032183.1 49474141 2866292 615293..617716 1 NC_005955.1 ATP-dependent protease lon 617716 lon1 2866292 lon1 Bartonella quintana str. Toulouse ATP-dependent protease lon YP_032183.1 615293 D 283165 CDS YP_032184.1 49474142 2867051 617945..618223 1 NC_005955.1 DNA-binding protein 618223 hupB 2867051 hupB Bartonella quintana str. Toulouse DNA-binding protein YP_032184.1 617945 D 283165 CDS YP_032185.1 49474143 2866666 complement(627456..627818) 1 NC_005955.1 response regulator 627818 2866666 BQ05210 Bartonella quintana str. Toulouse response regulator YP_032185.1 627456 R 283165 CDS YP_032186.1 49474144 2866950 complement(628461..629372) 1 NC_005955.1 lysophospholipase l2 629372 2866950 BQ05220 Bartonella quintana str. Toulouse lysophospholipase l2 YP_032186.1 628461 R 283165 CDS YP_032187.1 49474145 2866481 629647..630153 1 NC_005955.1 small heat shock protein 630153 ibpA2 2866481 ibpA2 Bartonella quintana str. Toulouse small heat shock protein YP_032187.1 629647 D 283165 CDS YP_032188.1 49474146 2866534 631076..631450 1 NC_005955.1 hypothetical protein 631450 2866534 BQ05250 Bartonella quintana str. Toulouse hypothetical protein YP_032188.1 631076 D 283165 CDS YP_032189.1 49474147 2866537 complement(632370..633299) 1 NC_005955.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 633299 2866537 BQ05270 Bartonella quintana str. Toulouse lipid A biosynthesis lauroyl acyltransferase YP_032189.1 632370 R 283165 CDS YP_032190.1 49474148 2866748 complement(633306..634334) 1 NC_005955.1 alcohol dehydrogenase 634334 adh 2866748 adh Bartonella quintana str. Toulouse alcohol dehydrogenase YP_032190.1 633306 R 283165 CDS YP_032191.1 49474149 2867017 complement(634396..635670) 1 NC_005955.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-ACP synthase 635670 fabF2 2867017 fabF2 Bartonella quintana str. Toulouse 3-oxoacyl-ACP synthase YP_032191.1 634396 R 283165 CDS YP_032192.1 49474150 2867026 complement(635685..636860) 1 NC_005955.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 636860 fabF3 2867026 fabF3 Bartonella quintana str. Toulouse 3-oxoacyl-ACP synthase YP_032192.1 635685 R 283165 CDS YP_032193.1 49474151 2867209 complement(636871..637155) 1 NC_005955.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein 637155 acpP2 2867209 acpP2 Bartonella quintana str. Toulouse acyl carrier protein YP_032193.1 636871 R 283165 CDS YP_032194.1 49474152 2867265 complement(637359..639668) 1 NC_005955.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate; malic enzyme 639668 2867265 BQ05320 Bartonella quintana str. Toulouse malic enzyme YP_032194.1 637359 R 283165 CDS YP_032195.1 49474153 2866670 complement(640636..645201) 1 NC_005955.1 hypothetical protein 645201 2866670 BQ05330 Bartonella quintana str. Toulouse hypothetical protein YP_032195.1 640636 R 283165 CDS YP_032196.1 49474154 2866580 645925..646164 1 NC_005955.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 646164 hfq 2866580 hfq Bartonella quintana str. Toulouse RNA-binding protein Hfq YP_032196.1 645925 D 283165 CDS YP_032197.1 49474155 2866453 646226..647569 1 NC_005955.1 GTP-binding protein HflX 647569 hflX 2866453 hflX Bartonella quintana str. Toulouse GTP-binding protein HflX YP_032197.1 646226 D 283165 CDS YP_032198.1 49474156 2867199 647713..649479 1 NC_005955.1 hypothetical protein 649479 2867199 BQ05360 Bartonella quintana str. Toulouse hypothetical protein YP_032198.1 647713 D 283165 CDS YP_032199.1 49474157 2867540 649636..650712 1 NC_005955.1 cytochrome c oxidase assembly protein 650712 2867540 BQ05370 Bartonella quintana str. Toulouse cytochrome c oxidase assembly protein YP_032199.1 649636 D 283165 CDS YP_032200.1 49474158 2867391 complement(650734..651669) 1 NC_005955.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 651669 argC 2867391 argC Bartonella quintana str. Toulouse N-acetyl-gamma-glutamyl-phosphate reductase YP_032200.1 650734 R 283165 CDS YP_032201.1 49474159 2867080 652005..653318 1 NC_005955.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 653318 glyA 2867080 glyA Bartonella quintana str. Toulouse serine hydroxymethyltransferase YP_032201.1 652005 D 283165 CDS YP_032202.1 49474160 2866457 653334..653816 1 NC_005955.1 transcriptional regulator NrdR 653816 nrdR 2866457 nrdR Bartonella quintana str. Toulouse transcriptional regulator NrdR YP_032202.1 653334 D 283165 CDS YP_032203.1 49474161 2867485 653839..654936 1 NC_005955.1 riboflavin biosynthesis protein ribD 654936 ribD 2867485 ribD Bartonella quintana str. Toulouse riboflavin biosynthesis protein ribD YP_032203.1 653839 D 283165 CDS YP_032204.1 49474162 2867449 654918..655538 1 NC_005955.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 655538 ribE 2867449 ribE Bartonella quintana str. Toulouse riboflavin synthase subunit alpha YP_032204.1 654918 D 283165 CDS YP_032205.1 49474163 2867102 655618..656076 1 NC_005955.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 656076 ribH 2867102 ribH Bartonella quintana str. Toulouse 6,7-dimethyl-8-ribityllumazine synthase YP_032205.1 655618 D 283165 CDS YP_032206.1 49474164 2867063 656079..656549 1 NC_005955.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 656549 nusB 2867063 nusB Bartonella quintana str. Toulouse transcription antitermination protein NusB YP_032206.1 656079 D 283165 CDS YP_032207.1 49474165 2867468 complement(656617..657096) 1 NC_005955.1 hypothetical protein 657096 2867468 BQ05450 Bartonella quintana str. Toulouse hypothetical protein YP_032207.1 656617 R 283165 CDS YP_032208.1 49474166 2867600 657333..657890 1 NC_005955.1 hypothetical protein 657890 2867600 BQ05460 Bartonella quintana str. Toulouse hypothetical protein YP_032208.1 657333 D 283165 CDS YP_032209.1 49474167 2866809 658047..659120 1 NC_005955.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 659120 plsX 2866809 plsX Bartonella quintana str. Toulouse glycerol-3-phosphate acyltransferase PlsX YP_032209.1 658047 D 283165 CDS YP_032210.1 49474168 2867022 659170..660144 1 NC_005955.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 660144 fabH 2867022 fabH Bartonella quintana str. Toulouse 3-oxoacyl-ACP synthase YP_032210.1 659170 D 283165 CDS YP_032211.1 49474169 2866488 660222..660536 1 NC_005955.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 660536 ihfA 2866488 ihfA Bartonella quintana str. Toulouse integration host factor subunit alpha YP_032211.1 660222 D 283165 CDS YP_032212.1 49474170 2867457 660744..661247 1 NC_005955.1 hypothetical protein 661247 2867457 BQ05500 Bartonella quintana str. Toulouse hypothetical protein YP_032212.1 660744 D 283165 CDS YP_032213.1 49474171 2866969 complement(661293..663269) 1 NC_005955.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 663269 thrS 2866969 thrS Bartonella quintana str. Toulouse threonyl-tRNA synthetase YP_032213.1 661293 R 283165 CDS YP_032214.1 49474172 2866560 complement(663390..663743) 1 NC_005955.1 hypothetical protein 663743 2866560 BQ05520 Bartonella quintana str. Toulouse hypothetical protein YP_032214.1 663390 R 283165 CDS YP_032215.1 49474173 2866471 complement(663744..664172) 1 NC_005955.1 hypothetical protein 664172 2866471 BQ05530 Bartonella quintana str. Toulouse hypothetical protein YP_032215.1 663744 R 283165 CDS YP_032216.1 49474174 2867402 664298..664918 1 NC_005955.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 664918 folE 2867402 folE Bartonella quintana str. Toulouse GTP cyclohydrolase I YP_032216.1 664298 D 283165 CDS YP_032217.1 49474175 2867586 665437..666507 1 NC_005955.1 hypothetical protein 666507 2867586 BQ05560 Bartonella quintana str. Toulouse hypothetical protein YP_032217.1 665437 D 283165 CDS YP_032218.1 49474176 2866958 666647..667141 1 NC_005955.1 hypothetical protein 667141 2866958 BQ05570 Bartonella quintana str. Toulouse hypothetical protein YP_032218.1 666647 D 283165 CDS YP_032219.1 49474177 2867105 669578..669943 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 669943 nuoA 2867105 nuoA Bartonella quintana str. Toulouse NADH dehydrogenase subunit A YP_032219.1 669578 D 283165 CDS YP_032220.1 49474178 2866508 669934..670515 1 NC_005955.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 670515 nuoB 2866508 nuoB Bartonella quintana str. Toulouse NADH dehydrogenase subunit B YP_032220.1 669934 D 283165 CDS YP_032221.1 49474179 2866525 670532..671140 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 671140 nuoC 2866525 nuoC Bartonella quintana str. Toulouse NADH dehydrogenase subunit C YP_032221.1 670532 D 283165 CDS YP_032222.1 49474180 2866689 671263..672453 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 672453 nuoD 2866689 nuoD Bartonella quintana str. Toulouse NADH dehydrogenase subunit D YP_032222.1 671263 D 283165 CDS YP_032223.1 49474181 2866478 672453..673103 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 673103 nuoE 2866478 nuoE Bartonella quintana str. Toulouse NADH dehydrogenase subunit E YP_032223.1 672453 D 283165 CDS YP_032224.1 49474182 2866519 673270..674577 1 NC_005955.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 674577 nuoF 2866519 nuoF Bartonella quintana str. Toulouse NADH dehydrogenase I subunit F YP_032224.1 673270 D 283165 CDS YP_032225.1 49474183 2866904 674641..676710 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 676710 nuoG 2866904 nuoG Bartonella quintana str. Toulouse NADH dehydrogenase subunit G YP_032225.1 674641 D 283165 CDS YP_032226.1 49474184 2866905 676733..677779 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 677779 nuoH 2866905 nuoH Bartonella quintana str. Toulouse NADH dehydrogenase subunit H YP_032226.1 676733 D 283165 CDS YP_032227.1 49474185 2866604 677794..678285 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 678285 nuoI 2866604 nuoI Bartonella quintana str. Toulouse NADH dehydrogenase subunit I YP_032227.1 677794 D 283165 CDS YP_032228.1 49474186 2866598 678386..679006 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 679006 nuoJ 2866598 nuoJ Bartonella quintana str. Toulouse NADH dehydrogenase subunit J YP_032228.1 678386 D 283165 CDS YP_032229.1 49474187 2866592 679016..679324 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 679324 nuoK 2866592 nuoK Bartonella quintana str. Toulouse NADH dehydrogenase subunit K YP_032229.1 679016 D 283165 CDS YP_032230.1 49474188 2866583 679331..681295 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 681295 nuoL 2866583 nuoL Bartonella quintana str. Toulouse NADH dehydrogenase subunit L YP_032230.1 679331 D 283165 CDS YP_032231.1 49474189 2866848 681295..682764 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 682764 nuoM 2866848 nuoM Bartonella quintana str. Toulouse NADH dehydrogenase subunit M YP_032231.1 681295 D 283165 CDS YP_032232.1 49474190 2866857 682783..684237 1 NC_005955.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 684237 nuoN 2866857 nuoN Bartonella quintana str. Toulouse NADH dehydrogenase subunit N YP_032232.1 682783 D 283165 CDS YP_032233.1 49474191 2867580 684237..685046 1 NC_005955.1 biotin-protein ligase birA 685046 birA 2867580 birA Bartonella quintana str. Toulouse biotin-protein ligase birA YP_032233.1 684237 D 283165 CDS YP_032234.1 49474192 2867352 685094..686770 1 NC_005955.1 hypothetical protein 686770 2867352 BQ05790 Bartonella quintana str. Toulouse hypothetical protein YP_032234.1 685094 D 283165 CDS YP_032235.1 49474193 2867221 686992..688317 1 NC_005955.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 688317 proS 2867221 proS Bartonella quintana str. Toulouse prolyl-tRNA synthetase YP_032235.1 686992 D 283165 CDS YP_032236.1 49474194 2866431 688333..689601 1 NC_005955.1 lipoprotein releasing system transmembrane protein lolC 689601 lolC 2866431 lolC Bartonella quintana str. Toulouse lipoprotein releasing system transmembrane protein lolC YP_032236.1 688333 D 283165 CDS YP_032237.1 49474195 2866286 689601..690281 1 NC_005955.1 lipoprotein releasing system ATP-binding protein lolD 690281 lolD 2866286 lolD Bartonella quintana str. Toulouse lipoprotein releasing system ATP-binding protein lolD YP_032237.1 689601 D 283165 CDS YP_032238.1 49474196 2866884 690358..690648 1 NC_005955.1 hypothetical protein 690648 2866884 BQ05830 Bartonella quintana str. Toulouse hypothetical protein YP_032238.1 690358 D 283165 CDS YP_032239.1 49474197 2866716 690654..694154 1 NC_005955.1 transcription repair coupling factor 694154 mfd 2866716 mfd Bartonella quintana str. Toulouse transcription repair coupling factor YP_032239.1 690654 D 283165 CDS YP_032240.1 49474198 2867254 696395..697006 1 NC_005955.1 hypothetical protein 697006 2867254 BQ05860 Bartonella quintana str. Toulouse hypothetical protein YP_032240.1 696395 D 283165 CDS YP_032241.1 49474199 2867220 complement(697099..699726) 1 NC_005955.1 ribonuclease E 699726 rne 2867220 rne Bartonella quintana str. Toulouse ribonuclease E YP_032241.1 697099 R 283165 CDS YP_032242.1 49474200 2866657 700330..701559 1 NC_005955.1 N-acetylmuramoyl-L-alanine amidase 701559 amiB 2866657 amiB Bartonella quintana str. Toulouse N-acetylmuramoyl-L-alanine amidase YP_032242.1 700330 D 283165 CDS YP_032243.1 49474201 2866631 701730..704192 1 NC_005955.1 penicillin-binding protein 1a 704192 mrcA2 2866631 mrcA2 Bartonella quintana str. Toulouse penicillin-binding protein 1a YP_032243.1 701730 D 283165 CDS YP_032244.1 49474202 2867358 704542..705510 1 NC_005955.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; peptide chain release factor 2 705510 prfB 2867358 prfB Bartonella quintana str. Toulouse peptide chain release factor 2 YP_032244.1 704542 D 283165 CDS YP_032245.1 49474203 2867582 complement(705665..706147) 1 NC_005955.1 bacterioferritin comigratory protein 706147 bcp 2867582 bcp Bartonella quintana str. Toulouse bacterioferritin comigratory protein YP_032245.1 705665 R 283165 CDS YP_032246.1 49474204 2866778 complement(706394..707647) 1 NC_005955.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 707647 tyrS 2866778 tyrS Bartonella quintana str. Toulouse tyrosyl-tRNA synthetase YP_032246.1 706394 R 283165 CDS YP_032247.1 49474205 2866712 complement(707943..708623) 1 NC_005955.1 hypothetical protein 708623 2866712 BQ05930 Bartonella quintana str. Toulouse hypothetical protein YP_032247.1 707943 R 283165 CDS YP_032248.1 49474206 2866434 708796..709941 1 NC_005955.1 nitrogenase cofactor synthesis protein nifS 709941 nifS1 2866434 nifS1 Bartonella quintana str. Toulouse nitrogenase cofactor synthesis protein nifS YP_032248.1 708796 D 283165 CDS YP_032249.1 49474207 2866703 710099..711610 1 NC_005955.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 711610 2866703 BQ05950 Bartonella quintana str. Toulouse cysteine desulfurase YP_032249.1 710099 D 283165 CDS YP_032250.1 49474208 2866511 711659..712414 1 NC_005955.1 ATP-dependent transporter 712414 2866511 BQ05960 Bartonella quintana str. Toulouse ATP-dependent transporter YP_032250.1 711659 D 283165 CDS YP_032251.1 49474209 2866800 712426..713694 1 NC_005955.1 hypothetical protein 713694 2866800 BQ05970 Bartonella quintana str. Toulouse hypothetical protein YP_032251.1 712426 D 283165 CDS YP_032252.1 49474210 2866414 713705..714949 1 NC_005955.1 nitrogenase cofactor synthesis protein nifS 714949 nifS2 2866414 nifS2 Bartonella quintana str. Toulouse nitrogenase cofactor synthesis protein nifS YP_032252.1 713705 D 283165 CDS YP_032253.1 49474211 2866658 714942..715346 1 NC_005955.1 hypothetical protein 715346 2866658 BQ05990 Bartonella quintana str. Toulouse hypothetical protein YP_032253.1 714942 D 283165 CDS YP_032254.1 49474212 2866847 715626..715826 1 NC_005955.1 hypothetical protein 715826 2866847 BQ06000 Bartonella quintana str. Toulouse hypothetical protein YP_032254.1 715626 D 283165 CDS YP_032255.1 49474213 2866641 complement(715985..716311) 1 NC_005955.1 hypothetical protein 716311 2866641 BQ06010 Bartonella quintana str. Toulouse hypothetical protein YP_032255.1 715985 R 283165 CDS YP_032256.1 49474214 2866709 complement(717357..718583) 1 NC_005955.1 2-octaprenyl-6-methoxyphenyl hydroxylase 718583 ubiH 2866709 ubiH Bartonella quintana str. Toulouse 2-octaprenyl-6-methoxyphenyl hydroxylase YP_032256.1 717357 R 283165 CDS YP_032257.1 49474215 2866538 718829..719530 1 NC_005955.1 phosphatidylcholine synthase 719530 pcsA 2866538 pcsA Bartonella quintana str. Toulouse phosphatidylcholine synthase YP_032257.1 718829 D 283165 CDS YP_032258.1 49474216 2867061 complement(721248..722060) 1 NC_005955.1 hypothetical protein 722060 2867061 BQ06070 Bartonella quintana str. Toulouse hypothetical protein YP_032258.1 721248 R 283165 CDS YP_032259.1 49474217 2867294 complement(722071..722844) 1 NC_005955.1 hypothetical protein 722844 2867294 BQ06080 Bartonella quintana str. Toulouse hypothetical protein YP_032259.1 722071 R 283165 CDS YP_032260.1 49474218 2867101 complement(722834..724393) 1 NC_005955.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 724393 metG 2867101 metG Bartonella quintana str. Toulouse methionyl-tRNA synthetase YP_032260.1 722834 R 283165 CDS YP_032261.1 49474219 2866728 complement(724454..725509) 1 NC_005955.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 725509 dnaC 2866728 dnaC Bartonella quintana str. Toulouse DNA polymerase III subunit delta' YP_032261.1 724454 R 283165 CDS YP_032262.1 49474220 2866806 complement(725506..726150) 1 NC_005955.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 726150 tmk 2866806 tmk Bartonella quintana str. Toulouse thymidylate kinase YP_032262.1 725506 R 283165 CDS YP_032263.1 49474221 2867436 complement(726181..727344) 1 NC_005955.1 penicillin-binding protein 727344 dacA1 2867436 dacA1 Bartonella quintana str. Toulouse penicillin-binding protein YP_032263.1 726181 R 283165 CDS YP_032264.1 49474222 2867200 complement(727837..728700) 1 NC_005955.1 rare lipoprotein A 728700 rlpA 2867200 rlpA Bartonella quintana str. Toulouse rare lipoprotein A YP_032264.1 727837 R 283165 CDS YP_032265.1 49474223 2866428 730755..731468 1 NC_005955.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 731468 lexA 2866428 lexA Bartonella quintana str. Toulouse LexA repressor YP_032265.1 730755 D 283165 CDS YP_032266.1 49474224 2867314 complement(733947..734564) 1 NC_005955.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 734564 rpsD 2867314 rpsD Bartonella quintana str. Toulouse 30S ribosomal protein S4 YP_032266.1 733947 R 283165 CDS YP_032267.1 49474225 2866852 complement(734747..735559) 1 NC_005955.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 735559 murI 2866852 murI Bartonella quintana str. Toulouse glutamate racemase YP_032267.1 734747 R 283165 CDS YP_032268.1 49474226 2866966 complement(735552..736388) 1 NC_005955.1 RNA methyltransferase 736388 2866966 BQ06210 Bartonella quintana str. Toulouse RNA methyltransferase YP_032268.1 735552 R 283165 CDS YP_032269.1 49474227 2867609 736719..737423 1 NC_005955.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 737423 sfsA 2867609 sfsA Bartonella quintana str. Toulouse sugar fermentation stimulation protein A YP_032269.1 736719 D 283165 CDS YP_032270.1 49474228 2866464 737416..738246 1 NC_005955.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 738246 map 2866464 map Bartonella quintana str. Toulouse methionine aminopeptidase YP_032270.1 737416 D 283165 CDS YP_032271.1 49474229 2867617 738264..739058 1 NC_005955.1 DNA repair protein radC 739058 radC 2867617 radC Bartonella quintana str. Toulouse DNA repair protein radC YP_032271.1 738264 D 283165 CDS YP_032272.1 49474230 2867446 complement(739104..739442) 1 NC_005955.1 hypothetical protein 739442 2867446 BQ06250 Bartonella quintana str. Toulouse hypothetical protein YP_032272.1 739104 R 283165 CDS YP_032273.1 49474231 2866518 complement(739951..740724) 1 NC_005955.1 hydrolase 740724 2866518 BQ06260 Bartonella quintana str. Toulouse hydrolase YP_032273.1 739951 R 283165 CDS YP_032274.1 49474232 2866822 complement(740721..741239) 1 NC_005955.1 hypothetical protein 741239 2866822 BQ06270 Bartonella quintana str. Toulouse hypothetical protein YP_032274.1 740721 R 283165 CDS YP_032275.1 49474233 2866767 complement(741495..742070) 1 NC_005955.1 cold shock protein 742070 2866767 BQ06280 Bartonella quintana str. Toulouse cold shock protein YP_032275.1 741495 R 283165 CDS YP_032276.1 49474234 2867166 742392..743525 1 NC_005955.1 branched chain amino acid ABC transporter periplasmic ligand-binding protein 743525 livJ 2867166 livJ Bartonella quintana str. Toulouse branched chain amino acid ABC transporter periplasmic ligand-binding protein YP_032276.1 742392 D 283165 CDS YP_032277.1 49474235 2867559 743656..744720 1 NC_005955.1 branched chain amino acid ABC transporter permease 744720 livH 2867559 livH Bartonella quintana str. Toulouse branched chain amino acid ABC transporter permease YP_032277.1 743656 D 283165 CDS YP_032278.1 49474236 2867579 744720..745778 1 NC_005955.1 high-affinity branched-chain amino acid transporter permease 745778 livM 2867579 livM Bartonella quintana str. Toulouse high-affinity branched-chain amino acid transporter permease YP_032278.1 744720 D 283165 CDS YP_032279.1 49474237 2867558 745775..746557 1 NC_005955.1 high-affinity branched-chain amino acid transport, ATP-binding protein 746557 livG 2867558 livG Bartonella quintana str. Toulouse high-affinity branched-chain amino acid transport, ATP-binding protein YP_032279.1 745775 D 283165 CDS YP_032280.1 49474238 2866329 746544..747254 1 NC_005955.1 high-affinity branched-chain amino acid transport, ATP-binding protein 747254 livF 2866329 livF Bartonella quintana str. Toulouse high-affinity branched-chain amino acid transport, ATP-binding protein YP_032280.1 746544 D 283165 CDS YP_032281.1 49474239 2866370 complement(747632..749122) 1 NC_005955.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 749122 gatA 2866370 gatA Bartonella quintana str. Toulouse aspartyl/glutamyl-tRNA amidotransferase subunit A YP_032281.1 747632 R 283165 CDS YP_032282.1 49474240 2867561 complement(749154..749441) 1 NC_005955.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 749441 gatC 2867561 gatC Bartonella quintana str. Toulouse aspartyl/glutamyl-tRNA amidotransferase subunit C YP_032282.1 749154 R 283165 CDS YP_032283.1 49474241 2867489 749587..750066 1 NC_005955.1 hypothetical protein 750066 2867489 BQ06360 Bartonella quintana str. Toulouse hypothetical protein YP_032283.1 749587 D 283165 CDS YP_032284.1 49474242 2866456 complement(750051..751847) 1 NC_005955.1 acyl-CoA dehydrogenase 751847 2866456 BQ06370 Bartonella quintana str. Toulouse acyl-CoA dehydrogenase YP_032284.1 750051 R 283165 CDS YP_032285.1 49474243 2867065 751806..752771 1 NC_005955.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 752771 pyrB 2867065 pyrB Bartonella quintana str. Toulouse aspartate carbamoyltransferase YP_032285.1 751806 D 283165 CDS YP_032286.1 49474244 2867064 752768..754063 1 NC_005955.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 754063 pyrC2 2867064 pyrC2 Bartonella quintana str. Toulouse dihydroorotase YP_032286.1 752768 D 283165 CDS YP_032287.1 49474245 2866619 754082..754717 1 NC_005955.1 hypothetical protein 754717 2866619 BQ06400 Bartonella quintana str. Toulouse hypothetical protein YP_032287.1 754082 D 283165 CDS YP_032288.1 49474246 2866700 754674..755906 1 NC_005955.1 DNA processing chain A 755906 dprA 2866700 dprA Bartonella quintana str. Toulouse DNA processing chain A YP_032288.1 754674 D 283165 CDS YP_032289.1 49474247 2866474 756308..758869 1 NC_005955.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 758869 topA 2866474 topA Bartonella quintana str. Toulouse DNA topoisomerase I YP_032289.1 756308 D 283165 CDS YP_032290.1 49474248 2867190 758873..761149 1 NC_005955.1 VacB and RNase II family exoribonuclease 761149 vacB 2867190 vacB Bartonella quintana str. Toulouse VacB and RNase II family exoribonuclease YP_032290.1 758873 D 283165 CDS YP_032291.1 49474249 2866885 762566..762733 1 NC_005955.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 762733 rpmG 2866885 rpmG Bartonella quintana str. Toulouse 50S ribosomal protein L33 YP_032291.1 762566 D 283165 CDS YP_032292.1 49474250 2866277 763205..763699 1 NC_005955.1 hypothetical protein 763699 2866277 BQ06450 Bartonella quintana str. Toulouse hypothetical protein YP_032292.1 763205 D 283165 CDS YP_032293.1 49474251 2866628 763749..764384 1 NC_005955.1 hypothetical protein 764384 2866628 BQ06460 Bartonella quintana str. Toulouse hypothetical protein YP_032293.1 763749 D 283165 CDS YP_032294.1 49474252 2867456 764415..764858 1 NC_005955.1 transcriptional regulator 764858 2867456 BQ06470 Bartonella quintana str. Toulouse transcriptional regulator YP_032294.1 764415 D 283165 CDS YP_032295.1 49474253 2867486 complement(766381..767361) 1 NC_005955.1 tRNA-dihydrouridine synthase A 767361 2867486 BQ06500 Bartonella quintana str. Toulouse tRNA-dihydrouridine synthase A YP_032295.1 766381 R 283165 CDS YP_032296.1 49474254 2866381 768460..768951 1 NC_005955.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 768951 accB 2866381 accB Bartonella quintana str. Toulouse acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_032296.1 768460 D 283165 CDS YP_032297.1 49474255 2866377 768966..770324 1 NC_005955.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 770324 accC 2866377 accC Bartonella quintana str. Toulouse acetyl-CoA carboxylase biotin carboxylase subunit YP_032297.1 768966 D 283165 CDS YP_032298.1 49474256 2866973 complement(770683..770913) 1 NC_005955.1 hypothetical protein 770913 2866973 BQ06550 Bartonella quintana str. Toulouse hypothetical protein YP_032298.1 770683 R 283165 CDS YP_032299.1 49474257 2867127 773810..774454 1 NC_005955.1 cytoplasmic membrane protein 774454 lemA 2867127 lemA Bartonella quintana str. Toulouse cytoplasmic membrane protein YP_032299.1 773810 D 283165 CDS YP_032300.1 49474258 2867493 774454..775305 1 NC_005955.1 hypothetical protein 775305 2867493 BQ06590 Bartonella quintana str. Toulouse hypothetical protein YP_032300.1 774454 D 283165 CDS YP_032301.1 49474259 2866323 775458..776195 1 NC_005955.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 776195 lipB 2866323 lipB Bartonella quintana str. Toulouse lipoate-protein ligase B YP_032301.1 775458 D 283165 CDS YP_032302.1 49474260 2866964 776279..778336 1 NC_005955.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 778336 parE 2866964 parE Bartonella quintana str. Toulouse DNA topoisomerase IV subunit B YP_032302.1 776279 D 283165 CDS YP_032303.1 49474261 2867612 complement(778357..780141) 1 NC_005955.1 single-stranded-DNA-specific exonuclease 780141 recJ 2867612 recJ Bartonella quintana str. Toulouse single-stranded-DNA-specific exonuclease YP_032303.1 778357 R 283165 CDS YP_032304.1 49474262 2866738 780432..780896 1 NC_005955.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 780896 rplM 2866738 rplM Bartonella quintana str. Toulouse 50S ribosomal protein L13 YP_032304.1 780432 D 283165 CDS YP_032305.1 49474263 2866724 780899..781384 1 NC_005955.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 781384 rpsI 2866724 rpsI Bartonella quintana str. Toulouse 30S ribosomal protein S9 YP_032305.1 780899 D 283165 CDS YP_032306.1 49474264 2866448 complement(781705..782070) 1 NC_005955.1 response regulator 782070 divK 2866448 divK Bartonella quintana str. Toulouse response regulator YP_032306.1 781705 R 283165 CDS YP_032307.1 49474265 2866808 784024..784293 1 NC_005955.1 hypothetical protein 784293 2866808 BQ06660 Bartonella quintana str. Toulouse hypothetical protein YP_032307.1 784024 D 283165 CDS YP_032308.1 49474266 2866648 complement(784811..787483) 1 NC_005955.1 hypothetical protein 787483 2866648 BQ06670 Bartonella quintana str. Toulouse hypothetical protein YP_032308.1 784811 R 283165 CDS YP_032309.1 49474267 2866642 complement(791293..792687) 1 NC_005955.1 amino acid permease 792687 2866642 BQ06710 Bartonella quintana str. Toulouse amino acid permease YP_032309.1 791293 R 283165 CDS YP_032310.1 49474268 2867461 complement(793986..794345) 1 NC_005955.1 hypothetical protein 794345 2867461 BQ06720 Bartonella quintana str. Toulouse hypothetical protein YP_032310.1 793986 R 283165 CDS YP_032311.1 49474269 2866572 complement(794782..796320) 1 NC_005955.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 796320 hutH 2866572 hutH Bartonella quintana str. Toulouse histidine ammonia-lyase YP_032311.1 794782 R 283165 CDS YP_032312.1 49474270 2866835 797097..797870 1 NC_005955.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 797870 ppnK 2866835 ppnK Bartonella quintana str. Toulouse inorganic polyphosphate/ATP-NAD kinase YP_032312.1 797097 D 283165 CDS YP_032313.1 49474271 2867508 798020..799423 1 NC_005955.1 ATP-dependent RNA helicase 799423 2867508 BQ06760 Bartonella quintana str. Toulouse ATP-dependent RNA helicase YP_032313.1 798020 D 283165 CDS YP_032314.1 49474272 2867044 complement(799485..800864) 1 NC_005955.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 800864 gltX 2867044 gltX Bartonella quintana str. Toulouse glutamyl-tRNA synthetase YP_032314.1 799485 R 283165 CDS YP_032315.1 49474273 2866306 complement(800875..802551) 1 NC_005955.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 802551 nadE 2866306 nadE Bartonella quintana str. Toulouse NAD synthetase YP_032315.1 800875 R 283165 CDS YP_032316.1 49474274 2867291 complement(802663..804042) 1 NC_005955.1 2-dehydro-3-deoxyphosphooctonate aldolase 804042 2867291 BQ06790 Bartonella quintana str. Toulouse 2-dehydro-3-deoxyphosphooctonate aldolase YP_032316.1 802663 R 283165 CDS YP_032317.1 49474275 2867278 complement(804118..805509) 1 NC_005955.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 805509 gor 2867278 gor Bartonella quintana str. Toulouse glutathione reductase YP_032317.1 804118 R 283165 CDS YP_032318.1 49474276 2867513 complement(805709..806266) 1 NC_005955.1 hypothetical protein 806266 2867513 BQ06810 Bartonella quintana str. Toulouse hypothetical protein YP_032318.1 805709 R 283165 CDS YP_032319.1 49474277 2866804 complement(806362..807066) 1 NC_005955.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 807066 rpiA 2866804 rpiA Bartonella quintana str. Toulouse ribose-5-phosphate isomerase A YP_032319.1 806362 R 283165 CDS YP_032320.1 49474278 2866450 complement(807540..809798) 1 NC_005955.1 DNA uptake protein 809798 2866450 BQ06830 Bartonella quintana str. Toulouse DNA uptake protein YP_032320.1 807540 R 283165 CDS YP_032321.1 49474279 2866836 809910..811337 1 NC_005955.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 811337 gltX 2866836 gltX Bartonella quintana str. Toulouse glutamyl-tRNA synthetase YP_032321.1 809910 D 283165 CDS YP_032322.1 49474280 2867054 811618..812934 1 NC_005955.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 812934 gltA 2867054 gltA Bartonella quintana str. Toulouse type II citrate synthase YP_032322.1 811618 D 283165 CDS YP_032323.1 49474281 2866332 814606..815358 1 NC_005955.1 ABC transporter periplasmic amino acid-binding protein 815358 2866332 BQ06860 Bartonella quintana str. Toulouse ABC transporter periplasmic amino acid-binding protein YP_032323.1 814606 D 283165 CDS YP_032324.1 49474282 2866816 815439..816158 1 NC_005955.1 ABC transporter permease 816158 2866816 BQ06870 Bartonella quintana str. Toulouse ABC transporter permease YP_032324.1 815439 D 283165 CDS YP_032325.1 49474283 2866282 816158..816865 1 NC_005955.1 ABC transporter permease 816865 2866282 BQ06880 Bartonella quintana str. Toulouse ABC transporter permease YP_032325.1 816158 D 283165 CDS YP_032326.1 49474284 2867129 816943..817716 1 NC_005955.1 amino-acid ABC transporter 817716 2867129 BQ06890 Bartonella quintana str. Toulouse amino-acid ABC transporter YP_032326.1 816943 D 283165 CDS YP_032327.1 49474285 2867399 complement(817735..818922) 1 NC_005955.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 818922 lpxB 2867399 lpxB Bartonella quintana str. Toulouse lipid-A-disaccharide synthase YP_032327.1 817735 R 283165 CDS YP_032328.1 49474286 2867432 complement(818915..819787) 1 NC_005955.1 phosphatidate cytidyltransferase 819787 cdsA1 2867432 cdsA1 Bartonella quintana str. Toulouse phosphatidate cytidyltransferase YP_032328.1 818915 R 283165 CDS YP_032329.1 49474287 2867062 complement(819790..820614) 1 NC_005955.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 820614 lpxA 2867062 lpxA Bartonella quintana str. Toulouse UDP-N-acetylglucosamine acyltransferase YP_032329.1 819790 R 283165 CDS YP_032330.1 49474288 2867029 complement(820637..821104) 1 NC_005955.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 821104 fabZ 2867029 fabZ Bartonella quintana str. Toulouse (3R)-hydroxymyristoyl-ACP dehydratase YP_032330.1 820637 R 283165 CDS YP_032331.1 49474289 2867496 complement(821106..822152) 1 NC_005955.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 822152 lpxD 2867496 lpxD Bartonella quintana str. Toulouse UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_032331.1 821106 R 283165 CDS YP_032332.1 49474290 2866335 complement(822219..824615) 1 NC_005955.1 hypothetical protein 824615 omp89 2866335 omp89 Bartonella quintana str. Toulouse hypothetical protein YP_032332.1 822219 R 283165 CDS YP_032333.1 49474291 2867004 complement(824827..825975) 1 NC_005955.1 zinc metalloprotease 825975 2867004 BQ06960 Bartonella quintana str. Toulouse zinc metalloprotease YP_032333.1 824827 R 283165 CDS YP_032334.1 49474292 2867417 complement(825991..826806) 1 NC_005955.1 phosphatidate cytidylyltransferase 826806 cdsA2 2867417 cdsA2 Bartonella quintana str. Toulouse phosphatidate cytidylyltransferase YP_032334.1 825991 R 283165 CDS YP_032335.1 49474293 2867412 complement(827532..828092) 1 NC_005955.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 828092 frr 2867412 frr Bartonella quintana str. Toulouse ribosome recycling factor YP_032335.1 827532 R 283165 CDS YP_032336.1 49474294 2866266 complement(828130..828849) 1 NC_005955.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 828849 pyrH 2866266 pyrH Bartonella quintana str. Toulouse uridylate kinase YP_032336.1 828130 R 283165 CDS YP_032337.1 49474295 2867217 complement(829009..829932) 1 NC_005955.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 829932 tsf 2867217 tsf Bartonella quintana str. Toulouse elongation factor Ts YP_032337.1 829009 R 283165 CDS YP_032338.1 49474296 2867317 complement(830044..830817) 1 NC_005955.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 830817 rpsB 2867317 rpsB Bartonella quintana str. Toulouse 30S ribosomal protein S2 YP_032338.1 830044 R 283165 CDS YP_032339.1 49474297 2867014 complement(830977..831801) 1 NC_005955.1 hypothetical protein 831801 2867014 BQ07020 Bartonella quintana str. Toulouse hypothetical protein YP_032339.1 830977 R 283165 CDS YP_032340.1 49474298 2866989 831946..832407 1 NC_005955.1 hypothetical protein 832407 2866989 BQ07030 Bartonella quintana str. Toulouse hypothetical protein YP_032340.1 831946 D 283165 CDS YP_032341.1 49474299 2866997 832548..832970 1 NC_005955.1 cell-cycle regulation Hit-like protein 832970 2866997 BQ07040 Bartonella quintana str. Toulouse cell-cycle regulation Hit-like protein YP_032341.1 832548 D 283165 CDS YP_032342.1 49474300 2866536 complement(832978..835329) 1 NC_005955.1 endopeptidase Clp ATP-binding chain a 835329 clpA 2866536 clpA Bartonella quintana str. Toulouse endopeptidase Clp ATP-binding chain a YP_032342.1 832978 R 283165 CDS YP_032343.1 49474301 2866983 complement(835336..835707) 1 NC_005955.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 835707 clpS 2866983 clpS Bartonella quintana str. Toulouse ATP-dependent Clp protease adaptor protein ClpS YP_032343.1 835336 R 283165 CDS YP_032344.1 49474302 2867440 835952..837304 1 NC_005955.1 penicillin-binding protein 837304 dacA2 2867440 dacA2 Bartonella quintana str. Toulouse penicillin-binding protein YP_032344.1 835952 D 283165 CDS YP_032345.1 49474303 2866970 837337..837615 1 NC_005955.1 hypothetical protein 837615 2866970 BQ07080 Bartonella quintana str. Toulouse hypothetical protein YP_032345.1 837337 D 283165 CDS YP_032346.1 49474304 2866879 complement(838121..839518) 1 NC_005955.1 L-serine dehydratase 839518 sdaA 2866879 sdaA Bartonella quintana str. Toulouse L-serine dehydratase YP_032346.1 838121 R 283165 CDS YP_032347.1 49474305 2866786 complement(839874..840563) 1 NC_005955.1 nitroreductase 840563 pnbA 2866786 pnbA Bartonella quintana str. Toulouse nitroreductase YP_032347.1 839874 R 283165 CDS YP_032348.1 49474306 2867342 complement(841781..845989) 1 NC_005955.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 845989 rpoC 2867342 rpoC Bartonella quintana str. Toulouse DNA-directed RNA polymerase subunit beta' YP_032348.1 841781 R 283165 CDS YP_032349.1 49474307 2866551 complement(846168..850319) 1 NC_005955.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 850319 rpoB 2866551 rpoB Bartonella quintana str. Toulouse DNA-directed RNA polymerase subunit beta YP_032349.1 846168 R 283165 CDS YP_032350.1 49474308 2866770 complement(850614..850985) 1 NC_005955.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 850985 rplL 2866770 rplL Bartonella quintana str. Toulouse 50S ribosomal protein L7/L12 YP_032350.1 850614 R 283165 CDS YP_032351.1 49474309 2866735 complement(851090..851608) 1 NC_005955.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 851608 rplJ 2866735 rplJ Bartonella quintana str. Toulouse 50S ribosomal protein L10 YP_032351.1 851090 R 283165 CDS YP_032352.1 49474310 2866772 complement(851977..852675) 1 NC_005955.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 852675 rplA 2866772 rplA Bartonella quintana str. Toulouse 50S ribosomal protein L1 YP_032352.1 851977 R 283165 CDS YP_032353.1 49474311 2866509 complement(852680..853108) 1 NC_005955.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 853108 rplK 2866509 rplK Bartonella quintana str. Toulouse 50S ribosomal protein L11 YP_032353.1 852680 R 283165 CDS YP_032354.1 49474312 2867085 complement(853257..853787) 1 NC_005955.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 853787 nusG 2867085 nusG Bartonella quintana str. Toulouse transcription antitermination protein NusG YP_032354.1 853257 R 283165 CDS YP_032355.1 49474313 2867289 complement(853808..854020) 1 NC_005955.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 854020 secE 2867289 secE Bartonella quintana str. Toulouse preprotein translocase subunit SecE YP_032355.1 853808 R 283165 CDS YP_032356.1 49474314 2866792 complement(854353..855528) 1 NC_005955.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 855528 tuf 2866792 tuf Bartonella quintana str. Toulouse elongation factor Tu YP_032356.1 854353 R 283165 CDS YP_032357.1 49474315 2867545 856122..856940 1 NC_005955.1 tRNA /rRNA methyltransferase 856940 2867545 BQ07240 Bartonella quintana str. Toulouse tRNA /rRNA methyltransferase YP_032357.1 856122 D 283165 CDS YP_032358.1 49474316 2866888 complement(856930..857670) 1 NC_005955.1 hypothetical protein 857670 2866888 BQ07250 Bartonella quintana str. Toulouse hypothetical protein YP_032358.1 856930 R 283165 CDS YP_032359.1 49474317 2867569 complement(858261..858686) 1 NC_005955.1 hypothetical protein 858686 2867569 BQ07260 Bartonella quintana str. Toulouse hypothetical protein YP_032359.1 858261 R 283165 CDS YP_032360.1 49474318 2866979 complement(858770..859168) 1 NC_005955.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 859168 2866979 BQ07270 Bartonella quintana str. Toulouse NADH dehydrogenase YP_032360.1 858770 R 283165 CDS YP_032361.1 49474319 2866369 complement(859351..860850) 1 NC_005955.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 860850 gatB 2866369 gatB Bartonella quintana str. Toulouse aspartyl/glutamyl-tRNA amidotransferase subunit B YP_032361.1 859351 R 283165 CDS YP_032362.1 49474320 2867262 complement(860981..862390) 1 NC_005955.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 862390 tig 2867262 tig Bartonella quintana str. Toulouse trigger factor YP_032362.1 860981 R 283165 CDS YP_032363.1 49474321 2866652 complement(865203..865508) 1 NC_005955.1 NADH-ubiquinone oxidoreductase 865508 2866652 BQ07330 Bartonella quintana str. Toulouse NADH-ubiquinone oxidoreductase YP_032363.1 865203 R 283165 CDS YP_032364.1 49474322 2866520 866061..866375 1 NC_005955.1 hypothetical protein 866375 2866520 BQ07350 Bartonella quintana str. Toulouse hypothetical protein YP_032364.1 866061 D 283165 CDS YP_032365.1 49474323 2866876 complement(866516..867205) 1 NC_005955.1 hypothetical protein 867205 2866876 BQ07360 Bartonella quintana str. Toulouse hypothetical protein YP_032365.1 866516 R 283165 CDS YP_032366.1 49474324 2867042 complement(867202..868413) 1 NC_005955.1 permease 868413 perM 2867042 perM Bartonella quintana str. Toulouse permease YP_032366.1 867202 R 283165 CDS YP_032367.1 49474325 2866350 868581..869666 1 NC_005955.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 869666 purM 2866350 purM Bartonella quintana str. Toulouse phosphoribosylaminoimidazole synthetase YP_032367.1 868581 D 283165 CDS YP_032368.1 49474326 2867075 869663..870274 1 NC_005955.1 phosphoribosylglycinamide formyltransferase 870274 purN 2867075 purN Bartonella quintana str. Toulouse phosphoribosylglycinamide formyltransferase YP_032368.1 869663 D 283165 CDS YP_032369.1 49474327 2867186 complement(870492..872981) 1 NC_005955.1 sensor histidine kinase 872981 2867186 BQ07400 Bartonella quintana str. Toulouse sensor histidine kinase YP_032369.1 870492 R 283165 CDS YP_032370.1 49474328 2866846 873257..873775 1 NC_005955.1 hypothetical protein 873775 2866846 BQ07410 Bartonella quintana str. Toulouse hypothetical protein YP_032370.1 873257 D 283165 CDS YP_032371.1 49474329 2866272 complement(873828..874244) 1 NC_005955.1 DnaK suppressor protein 874244 dksA 2866272 dksA Bartonella quintana str. Toulouse DnaK suppressor protein YP_032371.1 873828 R 283165 CDS YP_032372.1 49474330 2867108 complement(874576..875085) 1 NC_005955.1 4-hydroxyphenylacetate 3-monooxygenase 875085 nmoB 2867108 nmoB Bartonella quintana str. Toulouse 4-hydroxyphenylacetate 3-monooxygenase YP_032372.1 874576 R 283165 CDS YP_032373.1 49474331 2866789 875258..875932 1 NC_005955.1 Pentose (ribulose)-5-phosphate-3-epimerase 875932 rpe 2866789 rpe Bartonella quintana str. Toulouse Pentose (ribulose)-5-phosphate-3-epimerase YP_032373.1 875258 D 283165 CDS YP_032374.1 49474332 2867285 875942..877261 1 NC_005955.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 877261 purB 2867285 purB Bartonella quintana str. Toulouse adenylosuccinate lyase YP_032374.1 875942 D 283165 CDS YP_032375.1 49474333 2867549 877322..877870 1 NC_005955.1 hypothetical protein 877870 2867549 BQ07460 Bartonella quintana str. Toulouse hypothetical protein YP_032375.1 877322 D 283165 CDS YP_032376.1 49474334 2866820 878046..878810 1 NC_005955.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 878810 purC 2866820 purC Bartonella quintana str. Toulouse phosphoribosylaminoimidazole-succinocarboxamide synthase YP_032376.1 878046 D 283165 CDS YP_032377.1 49474335 2867502 878898..879137 1 NC_005955.1 hypothetical protein 879137 2867502 BQ07480 Bartonella quintana str. Toulouse hypothetical protein YP_032377.1 878898 D 283165 CDS YP_032378.1 49474336 2867076 879150..879821 1 NC_005955.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 879821 purQ 2867076 purQ Bartonella quintana str. Toulouse phosphoribosylformylglycinamidine synthase I YP_032378.1 879150 D 283165 CDS YP_032379.1 49474337 2867048 880112..882322 1 NC_005955.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 882322 purL 2867048 purL Bartonella quintana str. Toulouse phosphoribosylformylglycinamidine synthase II YP_032379.1 880112 D 283165 CDS YP_032380.1 49474338 2867497 882394..882627 1 NC_005955.1 hypothetical protein 882627 2867497 BQ07510 Bartonella quintana str. Toulouse hypothetical protein YP_032380.1 882394 D 283165 CDS YP_032381.1 49474339 2867476 882725..883057 1 NC_005955.1 hypothetical protein 883057 2867476 BQ07520 Bartonella quintana str. Toulouse hypothetical protein YP_032381.1 882725 D 283165 CDS YP_032382.1 49474340 2866365 883113..884381 1 NC_005955.1 bicyclomycin resistance protein 884381 2866365 BQ07530 Bartonella quintana str. Toulouse bicyclomycin resistance protein YP_032382.1 883113 D 283165 CDS YP_032383.1 49474341 2867013 complement(885344..887593) 1 NC_005955.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 887593 parC 2867013 parC Bartonella quintana str. Toulouse DNA topoisomerase IV subunit A YP_032383.1 885344 R 283165 CDS YP_032384.1 49474342 2866839 complement(888310..890103) 1 NC_005955.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 890103 aspS 2866839 aspS Bartonella quintana str. Toulouse aspartyl-tRNA synthetase YP_032384.1 888310 R 283165 CDS YP_032385.1 49474343 2867223 890177..891391 1 NC_005955.1 ribonuclease D 891391 rnd2 2867223 rnd2 Bartonella quintana str. Toulouse ribonuclease D YP_032385.1 890177 D 283165 CDS YP_032386.1 49474344 2867470 complement(891976..893487) 1 NC_005955.1 exopolyphosphatase 893487 2867470 BQ07580 Bartonella quintana str. Toulouse exopolyphosphatase YP_032386.1 891976 R 283165 CDS YP_032387.1 49474345 2866606 complement(893494..895683) 1 NC_005955.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 895683 ppk 2866606 ppk Bartonella quintana str. Toulouse polyphosphate kinase YP_032387.1 893494 R 283165 CDS YP_032388.1 49474346 2866408 895969..896208 1 NC_005955.1 hypothetical protein 896208 2866408 BQ07600 Bartonella quintana str. Toulouse hypothetical protein YP_032388.1 895969 D 283165 CDS YP_032389.1 49474347 2866823 896242..897477 1 NC_005955.1 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 897477 2866823 BQ07610 Bartonella quintana str. Toulouse salicylate hydroxylase YP_032389.1 896242 D 283165 CDS YP_032390.1 49474348 2866729 complement(897945..901433) 1 NC_005955.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 901433 dnaE 2866729 dnaE Bartonella quintana str. Toulouse DNA polymerase III subunit alpha YP_032390.1 897945 R 283165 CDS YP_032391.1 49474349 2867616 901842..903950 1 NC_005955.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 903950 recG 2867616 recG Bartonella quintana str. Toulouse ATP-dependent DNA helicase RecG YP_032391.1 901842 D 283165 CDS YP_032392.1 49474350 2867120 complement(904333..906156) 1 NC_005955.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 906156 glmS 2867120 glmS Bartonella quintana str. Toulouse glucosamine--fructose-6-phosphate aminotransferase YP_032392.1 904333 R 283165 CDS YP_032393.1 49474351 2867576 complement(906332..907678) 1 NC_005955.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 907678 glmU 2867576 glmU Bartonella quintana str. Toulouse bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_032393.1 906332 R 283165 CDS YP_032394.1 49474352 2867516 complement(907695..908483) 1 NC_005955.1 cytochrome c-type biogenesis protein 908483 2867516 BQ07660 Bartonella quintana str. Toulouse cytochrome c-type biogenesis protein YP_032394.1 907695 R 283165 CDS YP_032395.1 49474353 2866999 complement(908530..909540) 1 NC_005955.1 hypothetical protein 909540 2866999 BQ07670 Bartonella quintana str. Toulouse hypothetical protein YP_032395.1 908530 R 283165 CDS YP_032396.1 49474354 2866993 complement(909559..909882) 1 NC_005955.1 hypothetical protein 909882 2866993 BQ07680 Bartonella quintana str. Toulouse hypothetical protein YP_032396.1 909559 R 283165 CDS YP_032397.1 49474355 2866411 909990..911192 1 NC_005955.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 911192 dgt 2866411 dgt Bartonella quintana str. Toulouse deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_032397.1 909990 D 283165 CDS YP_032398.1 49474356 2866995 911223..912980 1 NC_005955.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 912980 argS 2866995 argS Bartonella quintana str. Toulouse arginyl-tRNA synthetase YP_032398.1 911223 D 283165 CDS YP_032399.1 49474357 2866801 913131..915653 1 NC_005955.1 hypothetical protein 915653 2866801 BQ07710 Bartonella quintana str. Toulouse hypothetical protein YP_032399.1 913131 D 283165 CDS YP_032400.1 49474358 2866990 complement(915769..916113) 1 NC_005955.1 hypothetical protein 916113 2866990 BQ07720 Bartonella quintana str. Toulouse hypothetical protein YP_032400.1 915769 R 283165 CDS YP_032401.1 49474359 2866382 916414..917520 1 NC_005955.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 917520 ilvE 2866382 ilvE Bartonella quintana str. Toulouse branched-chain amino acid aminotransferase YP_032401.1 916414 D 283165 CDS YP_032402.1 49474360 2867046 complement(917642..918628) 1 NC_005955.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 918628 glpX 2867046 glpX Bartonella quintana str. Toulouse fructose 1,6-bisphosphatase II YP_032402.1 917642 R 283165 CDS YP_032403.1 49474361 2866483 922330..923544 1 NC_005955.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 923544 icdA 2866483 icdA Bartonella quintana str. Toulouse isocitrate dehydrogenase YP_032403.1 922330 D 283165 CDS YP_032404.1 49474362 2867007 923659..925089 1 NC_005955.1 transport transmembrane protein 925089 2867007 BQ07790 Bartonella quintana str. Toulouse transport transmembrane protein YP_032404.1 923659 D 283165 CDS YP_032405.1 49474363 2867374 complement(928921..929433) 1 NC_005955.1 peptidyl prolyl cis-trans isomerase b 929433 ppiB1 2867374 ppiB1 Bartonella quintana str. Toulouse peptidyl prolyl cis-trans isomerase b YP_032405.1 928921 R 283165 CDS YP_032406.1 49474364 2867360 complement(929457..930047) 1 NC_005955.1 peptidyl-prolyl cis-trans isomerase b 930047 ppiB2 2867360 ppiB2 Bartonella quintana str. Toulouse peptidyl-prolyl cis-trans isomerase b YP_032406.1 929457 R 283165 CDS YP_032407.1 49474365 2867174 complement(930037..930555) 1 NC_005955.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 930555 coaD 2867174 coaD Bartonella quintana str. Toulouse phosphopantetheine adenylyltransferase YP_032407.1 930037 R 283165 CDS YP_032408.1 49474366 2867585 complement(930579..933356) 1 NC_005955.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 933356 gyrA 2867585 gyrA Bartonella quintana str. Toulouse DNA gyrase subunit A YP_032408.1 930579 R 283165 CDS YP_032409.1 49474367 2866358 complement(933590..934108) 1 NC_005955.1 single-strand binding protein (ssb) 934108 ssb 2866358 ssb Bartonella quintana str. Toulouse single-strand binding protein (ssb) YP_032409.1 933590 R 283165 CDS YP_032410.1 49474368 2867330 934447..937338 1 NC_005955.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 937338 uvrA 2867330 uvrA Bartonella quintana str. Toulouse excinuclease ABC subunit A YP_032410.1 934447 D 283165 CDS YP_032411.1 49474369 2866316 937635..937973 1 NC_005955.1 nitrogen regulatory protein p-II 937973 glnB 2866316 glnB Bartonella quintana str. Toulouse nitrogen regulatory protein p-II YP_032411.1 937635 D 283165 CDS YP_032412.1 49474370 2867170 938030..939439 1 NC_005955.1 glutamine synthetase I 939439 glnA2 2867170 glnA2 Bartonella quintana str. Toulouse glutamine synthetase I YP_032412.1 938030 D 283165 CDS YP_032413.1 49474371 2867473 939596..940141 1 NC_005955.1 hypothetical protein 940141 2867473 BQ07900 Bartonella quintana str. Toulouse hypothetical protein YP_032413.1 939596 D 283165 CDS YP_032414.1 49474372 2866401 complement(940185..940970) 1 NC_005955.1 hypothetical protein 940970 2866401 BQ07910 Bartonella quintana str. Toulouse hypothetical protein YP_032414.1 940185 R 283165 CDS YP_032415.1 49474373 2867237 complement(941583..942566) 1 NC_005955.1 ribosomal large subunit pseudouridine synthase c 942566 rluC 2867237 rluC Bartonella quintana str. Toulouse ribosomal large subunit pseudouridine synthase c YP_032415.1 941583 R 283165 CDS YP_032416.1 49474374 2866797 942777..944564 1 NC_005955.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABC transporter 944564 txpA 2866797 txpA Bartonella quintana str. Toulouse cyclic beta-1,2-glucan ABC transporter YP_032416.1 942777 D 283165 CDS YP_032417.1 49474375 2866696 complement(944765..947431) 1 NC_005955.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 947431 alaS 2866696 alaS Bartonella quintana str. Toulouse alanyl-tRNA synthetase YP_032417.1 944765 R 283165 CDS YP_032418.1 49474376 2867562 complement(947642..948685) 1 NC_005955.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 948685 recA 2867562 recA Bartonella quintana str. Toulouse recombinase A YP_032418.1 947642 R 283165 CDS YP_032419.1 49474377 2867239 complement(949291..950610) 1 NC_005955.1 recombination factor protein RarA 950610 2867239 BQ07960 Bartonella quintana str. Toulouse recombination factor protein RarA YP_032419.1 949291 R 283165 CDS YP_032420.1 49474378 2867515 complement(950619..952013) 1 NC_005955.1 heat shock protein 952013 htrA2 2867515 htrA2 Bartonella quintana str. Toulouse heat shock protein YP_032420.1 950619 R 283165 CDS YP_032421.1 49474379 2866773 complement(952275..952706) 1 NC_005955.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 952706 rplQ 2866773 rplQ Bartonella quintana str. Toulouse 50S ribosomal protein L17 YP_032421.1 952275 R 283165 CDS YP_032422.1 49474380 2866556 complement(952731..953744) 1 NC_005955.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 953744 rpoA 2866556 rpoA Bartonella quintana str. Toulouse DNA-directed RNA polymerase subunit alpha YP_032422.1 952731 R 283165 CDS YP_032423.1 49474381 2867188 complement(953838..954227) 1 NC_005955.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 954227 rpsK 2867188 rpsK Bartonella quintana str. Toulouse 30S ribosomal protein S11 YP_032423.1 953838 R 283165 CDS YP_032424.1 49474382 2867181 complement(954351..954719) 1 NC_005955.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 954719 rpsM 2867181 rpsM Bartonella quintana str. Toulouse 30S ribosomal protein S13 YP_032424.1 954351 R 283165 CDS YP_032425.1 49474383 2866521 complement(954900..955478) 1 NC_005955.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 955478 adk 2866521 adk Bartonella quintana str. Toulouse adenylate kinase YP_032425.1 954900 R 283165 CDS YP_032426.1 49474384 2867069 complement(955475..956821) 1 NC_005955.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 956821 secY 2867069 secY Bartonella quintana str. Toulouse preprotein translocase subunit SecY YP_032426.1 955475 R 283165 CDS YP_032427.1 49474385 2866507 complement(956947..957411) 1 NC_005955.1 late assembly protein; 50S ribosomal protein L15 957411 rplO 2866507 rplO Bartonella quintana str. Toulouse 50S ribosomal protein L15 YP_032427.1 956947 R 283165 CDS YP_032428.1 49474386 2866661 complement(957431..957637) 1 NC_005955.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 957637 rpmD 2866661 rpmD Bartonella quintana str. Toulouse 50S ribosomal protein L30 YP_032428.1 957431 R 283165 CDS YP_032429.1 49474387 2867310 complement(957669..958217) 1 NC_005955.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 958217 rpsE 2867310 rpsE Bartonella quintana str. Toulouse 30S ribosomal protein S5 YP_032429.1 957669 R 283165 CDS YP_032430.1 49474388 2866765 complement(958331..958693) 1 NC_005955.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 958693 rplR 2866765 rplR Bartonella quintana str. Toulouse 50S ribosomal protein L18 YP_032430.1 958331 R 283165 CDS YP_032431.1 49474389 2866744 complement(958706..959239) 1 NC_005955.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 959239 rplF 2866744 rplF Bartonella quintana str. Toulouse 50S ribosomal protein L6 YP_032431.1 958706 R 283165 CDS YP_032432.1 49474390 2866731 complement(959278..959676) 1 NC_005955.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 959676 rpsH 2866731 rpsH Bartonella quintana str. Toulouse 30S ribosomal protein S8 YP_032432.1 959278 R 283165 CDS YP_032433.1 49474391 2867093 complement(959691..959996) 1 NC_005955.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 959996 rpsN 2867093 rpsN Bartonella quintana str. Toulouse 30S ribosomal protein S14 YP_032433.1 959691 R 283165 CDS YP_032434.1 49474392 2866743 complement(960021..960578) 1 NC_005955.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 960578 rplE 2866743 rplE Bartonella quintana str. Toulouse 50S ribosomal protein L5 YP_032434.1 960021 R 283165 CDS YP_032435.1 49474393 2866688 complement(960571..960885) 1 NC_005955.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 960885 rplX 2866688 rplX Bartonella quintana str. Toulouse 50S ribosomal protein L24 YP_032435.1 960571 R 283165 CDS YP_032436.1 49474394 2866506 complement(960898..961266) 1 NC_005955.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 961266 rplN 2866506 rplN Bartonella quintana str. Toulouse 50S ribosomal protein L14 YP_032436.1 960898 R 283165 CDS YP_032437.1 49474395 2867526 complement(961411..961650) 1 NC_005955.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 961650 rpsQ 2867526 rpsQ Bartonella quintana str. Toulouse 30S ribosomal protein S17 YP_032437.1 961411 R 283165 CDS YP_032438.1 49474396 2866660 complement(961663..961863) 1 NC_005955.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 961863 rpmC 2866660 rpmC Bartonella quintana str. Toulouse 50S ribosomal protein L29 YP_032438.1 961663 R 283165 CDS YP_032439.1 49474397 2866741 complement(961876..962289) 1 NC_005955.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 962289 rplP 2866741 rplP Bartonella quintana str. Toulouse 50S ribosomal protein L16 YP_032439.1 961876 R 283165 CDS YP_032440.1 49474398 2867315 complement(962326..963036) 1 NC_005955.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 963036 rpsC 2867315 rpsC Bartonella quintana str. Toulouse 30S ribosomal protein S3 YP_032440.1 962326 R 283165 CDS YP_032441.1 49474399 2866777 complement(963036..963425) 1 NC_005955.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 963425 rplV 2866777 rplV Bartonella quintana str. Toulouse 50S ribosomal protein L22 YP_032441.1 963036 R 283165 CDS YP_032442.1 49474400 2866862 complement(963428..963706) 1 NC_005955.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 963706 rpsS 2866862 rpsS Bartonella quintana str. Toulouse 30S ribosomal protein S19 YP_032442.1 963428 R 283165 CDS YP_032443.1 49474401 2866771 complement(963722..964555) 1 NC_005955.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 964555 rplB 2866771 rplB Bartonella quintana str. Toulouse 50S ribosomal protein L2 YP_032443.1 963722 R 283165 CDS YP_032444.1 49474402 2866526 complement(964578..964871) 1 NC_005955.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 964871 rplW 2866526 rplW Bartonella quintana str. Toulouse 50S ribosomal protein L23 YP_032444.1 964578 R 283165 CDS YP_032445.1 49474403 2866749 complement(964868..965488) 1 NC_005955.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 965488 rplD 2866749 rplD Bartonella quintana str. Toulouse 50S ribosomal protein L4 YP_032445.1 964868 R 283165 CDS YP_032446.1 49474404 2866755 complement(965488..966228) 1 NC_005955.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 966228 rplC 2866755 rplC Bartonella quintana str. Toulouse 50S ribosomal protein L3 YP_032446.1 965488 R 283165 CDS YP_032447.1 49474405 2866720 complement(966256..966564) 1 NC_005955.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 966564 rpsJ 2866720 rpsJ Bartonella quintana str. Toulouse 30S ribosomal protein S10 YP_032447.1 966256 R 283165 CDS YP_032448.1 49474406 2866791 complement(966629..967804) 1 NC_005955.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 967804 tuf 2866791 tuf Bartonella quintana str. Toulouse elongation factor Tu YP_032448.1 966629 R 283165 CDS YP_032449.1 49474407 2867438 complement(967868..969952) 1 NC_005955.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 969952 fusA 2867438 fusA Bartonella quintana str. Toulouse elongation factor G YP_032449.1 967868 R 283165 CDS YP_032450.1 49474408 2866730 complement(969980..970450) 1 NC_005955.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 970450 rpsG 2866730 rpsG Bartonella quintana str. Toulouse 30S ribosomal protein S7 YP_032450.1 969980 R 283165 CDS YP_032451.1 49474409 2867185 complement(970469..970840) 1 NC_005955.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 970840 rpsL 2867185 rpsL Bartonella quintana str. Toulouse 30S ribosomal protein S12 YP_032451.1 970469 R 283165 CDS YP_032452.1 49474410 2866894 971373..972155 1 NC_005955.1 exodeoxyribonuclease III 972155 xthA1 2866894 xthA1 Bartonella quintana str. Toulouse exodeoxyribonuclease III YP_032452.1 971373 D 283165 CDS YP_032453.1 49474411 2867356 972281..973192 1 NC_005955.1 amino-acid ABC transporter binding protein 973192 ybeJ 2867356 ybeJ Bartonella quintana str. Toulouse amino-acid ABC transporter binding protein YP_032453.1 972281 D 283165 CDS YP_032454.1 49474412 2866346 973334..974086 1 NC_005955.1 amino acid permease 974086 gltJ 2866346 gltJ Bartonella quintana str. Toulouse amino acid permease YP_032454.1 973334 D 283165 CDS YP_032455.1 49474413 2867057 974089..974805 1 NC_005955.1 amino acid permease 974805 gltK 2867057 gltK Bartonella quintana str. Toulouse amino acid permease YP_032455.1 974089 D 283165 CDS YP_032456.1 49474414 2867047 974842..975588 1 NC_005955.1 glutamate /aspartate transport ATP-binding protein 975588 gltL 2867047 gltL Bartonella quintana str. Toulouse glutamate /aspartate transport ATP-binding protein YP_032456.1 974842 D 283165 CDS YP_032457.1 49474415 2867191 complement(977039..979762) 1 NC_005955.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 979762 valS 2867191 valS Bartonella quintana str. Toulouse valyl-tRNA synthetase YP_032457.1 977039 R 283165 CDS YP_032458.1 49474416 2866491 complement(979923..980489) 1 NC_005955.1 hypothetical protein 980489 2866491 BQ08360 Bartonella quintana str. Toulouse hypothetical protein YP_032458.1 979923 R 283165 CDS YP_032459.1 49474417 2866869 complement(980737..982062) 1 NC_005955.1 hypothetical protein 982062 2866869 BQ08370 Bartonella quintana str. Toulouse hypothetical protein YP_032459.1 980737 R 283165 CDS YP_032460.1 49474418 2867494 complement(982095..982769) 1 NC_005955.1 protein-L-isoaspartate(D-aspartate) O-methyltransferase 982769 pcm2 2867494 pcm2 Bartonella quintana str. Toulouse protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_032460.1 982095 R 283165 CDS YP_032461.1 49474419 2867169 complement(985786..986685) 1 NC_005955.1 hemin binding protein E 986685 hbpE 2867169 hbpE Bartonella quintana str. Toulouse hemin binding protein E YP_032461.1 985786 R 283165 CDS YP_032462.1 49474420 2866971 complement(987730..988002) 1 NC_005955.1 hypothetical protein 988002 2866971 BQ08440 Bartonella quintana str. Toulouse hypothetical protein YP_032462.1 987730 R 283165 CDS YP_032463.1 49474421 2867023 complement(987996..990371) 1 NC_005955.1 hypothetical protein 990371 2867023 BQ08450 Bartonella quintana str. Toulouse hypothetical protein YP_032463.1 987996 R 283165 CDS YP_032464.1 49474422 2866439 990543..990926 1 NC_005955.1 hypothetical protein 990926 2866439 BQ08460 Bartonella quintana str. Toulouse hypothetical protein YP_032464.1 990543 D 283165 CDS YP_032465.1 49474423 2867072 991006..993519 1 NC_005955.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 993519 secD 2867072 secD Bartonella quintana str. Toulouse bifunctional preprotein translocase subunit SecD/SecF YP_032465.1 991006 D 283165 CDS YP_032466.1 49474424 2866945 993620..995374 1 NC_005955.1 potassium-efflux system protein 995374 2866945 BQ08490 Bartonella quintana str. Toulouse potassium-efflux system protein YP_032466.1 993620 D 283165 CDS YP_032467.1 49474425 2866455 995403..996356 1 NC_005955.1 hypothetical protein 996356 2866455 BQ08500 Bartonella quintana str. Toulouse hypothetical protein YP_032467.1 995403 D 283165 CDS YP_032468.1 49474426 2866419 complement(997064..998629) 1 NC_005955.1 hypothetical protein 998629 2866419 BQ08510 Bartonella quintana str. Toulouse hypothetical protein YP_032468.1 997064 R 283165 CDS YP_032469.1 49474427 2867293 1001119..1002522 1 NC_005955.1 D-serine /D-alanine /glycine transporter 1002522 cycA 2867293 cycA Bartonella quintana str. Toulouse D-serine /D-alanine /glycine transporter YP_032469.1 1001119 D 283165 CDS YP_032470.1 49474428 2866764 complement(1002613..1003632) 1 NC_005955.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1003632 ilvC 2866764 ilvC Bartonella quintana str. Toulouse ketol-acid reductoisomerase YP_032470.1 1002613 R 283165 CDS YP_032471.1 49474429 2867283 complement(1005263..1005997) 1 NC_005955.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1005997 pdxJ 2867283 pdxJ Bartonella quintana str. Toulouse pyridoxine 5'-phosphate synthase YP_032471.1 1005263 R 283165 CDS YP_032472.1 49474430 2867000 complement(1006085..1007206) 1 NC_005955.1 hypothetical protein 1007206 2867000 BQ08560 Bartonella quintana str. Toulouse hypothetical protein YP_032472.1 1006085 R 283165 CDS YP_032473.1 49474431 2866649 complement(1009624..1010511) 1 NC_005955.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1010511 miaA 2866649 miaA Bartonella quintana str. Toulouse tRNA delta(2)-isopentenylpyrophosphate transferase YP_032473.1 1009624 R 283165 CDS YP_032474.1 49474432 2867043 complement(1011143..1012660) 1 NC_005955.1 Serine protease 1012660 htrA3 2867043 htrA3 Bartonella quintana str. Toulouse Serine protease YP_032474.1 1011143 R 283165 CDS YP_032475.1 49474433 2866340 complement(1012816..1013763) 1 NC_005955.1 ftsH protease activity modulator hflC 1013763 hflC 2866340 hflC Bartonella quintana str. Toulouse ftsH protease activity modulator hflC YP_032475.1 1012816 R 283165 CDS YP_032476.1 49474434 2866303 complement(1013766..1014911) 1 NC_005955.1 protease subunit hflK 1014911 hflK 2866303 hflK Bartonella quintana str. Toulouse protease subunit hflK YP_032476.1 1013766 R 283165 CDS YP_032477.1 49474435 2867396 complement(1015020..1015541) 1 NC_005955.1 dihydrofolate reductase 1015541 folA 2867396 folA Bartonella quintana str. Toulouse dihydrofolate reductase YP_032477.1 1015020 R 283165 CDS YP_032478.1 49474436 2866546 complement(1015538..1016332) 1 NC_005955.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1016332 thyA 2866546 thyA Bartonella quintana str. Toulouse thymidylate synthase YP_032478.1 1015538 R 283165 CDS YP_032479.1 49474437 2867590 1016543..1017850 1 NC_005955.1 alpha-ketoglutarate permease 1017850 kgtP 2867590 kgtP Bartonella quintana str. Toulouse alpha-ketoglutarate permease YP_032479.1 1016543 D 283165 CDS YP_032480.1 49474438 2866405 complement(1020421..1020726) 1 NC_005955.1 hypothetical protein 1020726 2866405 BQ08670 Bartonella quintana str. Toulouse hypothetical protein YP_032480.1 1020421 R 283165 CDS YP_032481.1 49474439 2866843 1021343..1021888 1 NC_005955.1 hypothetical protein 1021888 2866843 BQ08680 Bartonella quintana str. Toulouse hypothetical protein YP_032481.1 1021343 D 283165 CDS YP_032482.1 49474440 2866445 1021901..1022083 1 NC_005955.1 hypothetical protein 1022083 2866445 BQ08690 Bartonella quintana str. Toulouse hypothetical protein YP_032482.1 1021901 D 283165 CDS YP_032483.1 49474441 2866300 1022127..1022414 1 NC_005955.1 hypothetical protein 1022414 2866300 BQ08700 Bartonella quintana str. Toulouse hypothetical protein YP_032483.1 1022127 D 283165 CDS YP_032484.1 49474442 2867312 1022471..1024801 1 NC_005955.1 DNA helicase II 1024801 uvrD 2867312 uvrD Bartonella quintana str. Toulouse DNA helicase II YP_032484.1 1022471 D 283165 CDS YP_032485.1 49474443 2867362 1025565..1026146 1 NC_005955.1 sco1/2 family protein 1026146 2867362 BQ08730 Bartonella quintana str. Toulouse sco1/2 family protein YP_032485.1 1025565 D 283165 CDS YP_032486.1 49474444 2867172 1026178..1027047 1 NC_005955.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1027047 prmA 2867172 prmA Bartonella quintana str. Toulouse ribosomal protein L11 methyltransferase YP_032486.1 1026178 D 283165 CDS YP_032487.1 49474445 2867539 1027065..1028891 1 NC_005955.1 aminopeptidase 1028891 2867539 BQ08750 Bartonella quintana str. Toulouse aminopeptidase YP_032487.1 1027065 D 283165 CDS YP_032488.1 49474446 2866441 complement(1029435..1031594) 1 NC_005955.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1031594 ligA 2866441 ligA Bartonella quintana str. Toulouse NAD-dependent DNA ligase LigA YP_032488.1 1029435 R 283165 CDS YP_032489.1 49474447 2867613 complement(1031724..1033385) 1 NC_005955.1 DNA repair protein recN 1033385 recN 2867613 recN Bartonella quintana str. Toulouse DNA repair protein recN YP_032489.1 1031724 R 283165 CDS YP_032490.1 49474448 2866516 complement(1033392..1034285) 1 NC_005955.1 competence lipoprotein comL precursor 1034285 comL 2866516 comL Bartonella quintana str. Toulouse competence lipoprotein comL precursor YP_032490.1 1033392 R 283165 CDS YP_032491.1 49474449 2867400 complement(1034456..1035328) 1 NC_005955.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1035328 lpxC 2867400 lpxC Bartonella quintana str. Toulouse UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_032491.1 1034456 R 283165 CDS YP_032492.1 49474450 2867434 complement(1035545..1037317) 1 NC_005955.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1037317 ftsZ 2867434 ftsZ Bartonella quintana str. Toulouse cell division protein FtsZ YP_032492.1 1035545 R 283165 CDS YP_032493.1 49474451 2867418 complement(1037389..1038687) 1 NC_005955.1 cell division protein ftsA 1038687 ftsA 2867418 ftsA Bartonella quintana str. Toulouse cell division protein ftsA YP_032493.1 1037389 R 283165 CDS YP_032494.1 49474452 2867428 complement(1038687..1039616) 1 NC_005955.1 cell division protein FtsQ 1039616 ftsQ 2867428 ftsQ Bartonella quintana str. Toulouse cell division protein FtsQ YP_032494.1 1038687 R 283165 CDS YP_032495.1 49474453 2867175 complement(1039583..1040503) 1 NC_005955.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1040503 ddl 2867175 ddl Bartonella quintana str. Toulouse D-alanine--D-alanine ligase YP_032495.1 1039583 R 283165 CDS YP_032496.1 49474454 2867338 complement(1040754..1041800) 1 NC_005955.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1041800 murB 2867338 murB Bartonella quintana str. Toulouse UDP-N-acetylenolpyruvoylglucosamine reductase YP_032496.1 1040754 R 283165 CDS YP_032497.1 49474455 2866914 complement(1041700..1043127) 1 NC_005955.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1043127 murC 2866914 murC Bartonella quintana str. Toulouse UDP-N-acetylmuramate--L-alanine ligase YP_032497.1 1041700 R 283165 CDS YP_032498.1 49474456 2866590 complement(1043111..1044247) 1 NC_005955.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1044247 murG 2866590 murG Bartonella quintana str. Toulouse undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_032498.1 1043111 R 283165 CDS YP_032499.1 49474457 2867425 complement(1044237..1045394) 1 NC_005955.1 cell division protein ftsW 1045394 ftsW 2867425 ftsW Bartonella quintana str. Toulouse cell division protein ftsW YP_032499.1 1044237 R 283165 CDS YP_032500.1 49474458 2867307 complement(1045526..1046926) 1 NC_005955.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1046926 murD 2867307 murD Bartonella quintana str. Toulouse UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_032500.1 1045526 R 283165 CDS YP_032501.1 49474459 2866621 complement(1046931..1048001) 1 NC_005955.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1048001 mraY 2866621 mraY Bartonella quintana str. Toulouse phospho-N-acetylmuramoyl-pentapeptide- transferase YP_032501.1 1046931 R 283165 CDS YP_032502.1 49474460 2866593 complement(1048023..1049444) 1 NC_005955.1 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanine ligase 1049444 murF 2866593 murF Bartonella quintana str. Toulouse UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanine ligase YP_032502.1 1048023 R 283165 CDS YP_032503.1 49474461 2867308 complement(1049441..1050892) 1 NC_005955.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1050892 murE 2867308 murE Bartonella quintana str. Toulouse UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_032503.1 1049441 R 283165 CDS YP_032504.1 49474462 2867421 complement(1050916..1052658) 1 NC_005955.1 penicillin-binding protein 1052658 ftsI 2867421 ftsI Bartonella quintana str. Toulouse penicillin-binding protein YP_032504.1 1050916 R 283165 CDS YP_032505.1 49474463 2866366 complement(1052658..1053062) 1 NC_005955.1 hypothetical protein 1053062 2866366 BQ08930 Bartonella quintana str. Toulouse hypothetical protein YP_032505.1 1052658 R 283165 CDS YP_032506.1 49474464 2866353 complement(1053059..1054057) 1 NC_005955.1 S-adenosyl-methyltransferase MraW 1054057 mraW 2866353 mraW Bartonella quintana str. Toulouse S-adenosyl-methyltransferase MraW YP_032506.1 1053059 R 283165 CDS YP_032507.1 49474465 2867514 complement(1054835..1055344) 1 NC_005955.1 transmembrane protein 1055344 2867514 BQ08970 Bartonella quintana str. Toulouse transmembrane protein YP_032507.1 1054835 R 283165 CDS YP_032508.1 49474466 2867550 complement(1056287..1056661) 1 NC_005955.1 hypothetical protein 1056661 2867550 BQ08980 Bartonella quintana str. Toulouse hypothetical protein YP_032508.1 1056287 R 283165 CDS YP_032509.1 49474467 2867359 complement(1059701..1061350) 1 NC_005955.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1061350 2867359 BQ09000 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032509.1 1059701 R 283165 CDS YP_032510.1 49474468 2867197 1061518..1062060 1 NC_005955.1 hypothetical protein 1062060 2867197 BQ09010 Bartonella quintana str. Toulouse hypothetical protein YP_032510.1 1061518 D 283165 CDS YP_032511.1 49474469 2866774 1062101..1062709 1 NC_005955.1 pyrazinamidase /nicotinamidase pnca 1062709 pncA 2866774 pncA Bartonella quintana str. Toulouse pyrazinamidase /nicotinamidase pnca YP_032511.1 1062101 D 283165 CDS YP_032512.1 49474470 2866980 complement(1062757..1063809) 1 NC_005955.1 hypothetical protein 1063809 2866980 BQ09030 Bartonella quintana str. Toulouse hypothetical protein YP_032512.1 1062757 R 283165 CDS YP_032513.1 49474471 2866285 1064161..1064700 1 NC_005955.1 hypothetical protein 1064700 2866285 BQ09040 Bartonella quintana str. Toulouse hypothetical protein YP_032513.1 1064161 D 283165 CDS YP_032514.1 49474472 2867192 1065121..1065300 1 NC_005955.1 hypothetical protein 1065300 2867192 BQ09050 Bartonella quintana str. Toulouse hypothetical protein YP_032514.1 1065121 D 283165 CDS YP_032515.1 49474473 2866998 complement(1068192..1068506) 1 NC_005955.1 phage related protein 1068506 2866998 BQ09070 Bartonella quintana str. Toulouse phage related protein YP_032515.1 1068192 R 283165 CDS YP_032516.1 49474474 2867123 1069758..1070072 1 NC_005955.1 hypothetical protein 1070072 2867123 BQ09100 Bartonella quintana str. Toulouse hypothetical protein YP_032516.1 1069758 D 283165 CDS YP_032517.1 49474475 2866429 1072837..1073574 1 NC_005955.1 hypothetical protein 1073574 2866429 BQ09140 Bartonella quintana str. Toulouse hypothetical protein YP_032517.1 1072837 D 283165 CDS YP_032518.1 49474476 2867337 complement(1075641..1077653) 1 NC_005955.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1077653 rpoD 2867337 rpoD Bartonella quintana str. Toulouse RNA polymerase sigma factor RpoD YP_032518.1 1075641 R 283165 CDS YP_032519.1 49474477 2866669 complement(1078007..1079935) 1 NC_005955.1 synthesizes RNA primers at the replication forks; DNA primase 1079935 dnaG 2866669 dnaG Bartonella quintana str. Toulouse DNA primase YP_032519.1 1078007 R 283165 CDS YP_032520.1 49474478 2867578 1080071..1081288 1 NC_005955.1 hypothetical protein 1081288 2867578 BQ09180 Bartonella quintana str. Toulouse hypothetical protein YP_032520.1 1080071 D 283165 CDS YP_032521.1 49474479 2866588 1083650..1083901 1 NC_005955.1 hypothetical protein 1083901 2866588 BQ09200 Bartonella quintana str. Toulouse hypothetical protein YP_032521.1 1083650 D 283165 CDS YP_032522.1 49474480 2866638 1085154..1085672 1 NC_005955.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 1085672 ubiC 2866638 ubiC Bartonella quintana str. Toulouse chorismate pyruvate lyase YP_032522.1 1085154 D 283165 CDS YP_032523.1 49474481 2867568 1086849..1088045 1 NC_005955.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1088045 carA 2867568 carA Bartonella quintana str. Toulouse carbamoyl phosphate synthase small subunit YP_032523.1 1086849 D 283165 CDS YP_032524.1 49474482 2866301 complement(1088211..1089431) 1 NC_005955.1 transporter 1089431 2866301 BQ09230 Bartonella quintana str. Toulouse transporter YP_032524.1 1088211 R 283165 CDS YP_032525.1 49474483 2867565 1090791..1094276 1 NC_005955.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1094276 carB 2867565 carB Bartonella quintana str. Toulouse carbamoyl phosphate synthase large subunit YP_032525.1 1090791 D 283165 CDS YP_032526.1 49474484 2867581 1094530..1094739 1 NC_005955.1 cold shock protein 1094739 2867581 BQ09250 Bartonella quintana str. Toulouse cold shock protein YP_032526.1 1094530 D 283165 CDS YP_032527.1 49474485 2867587 1095076..1096278 1 NC_005955.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1096278 aatA 2867587 aatA Bartonella quintana str. Toulouse aspartate aminotransferase YP_032527.1 1095076 D 283165 CDS YP_032528.1 49474486 2867621 complement(1097094..1097999) 1 NC_005955.1 LysR family transcriptional regulator 1097999 2867621 BQ09270 Bartonella quintana str. Toulouse LysR family transcriptional regulator YP_032528.1 1097094 R 283165 CDS YP_032529.1 49474487 2867216 complement(1098056..1099009) 1 NC_005955.1 thioredoxin reductase 1099009 trxB 2867216 trxB Bartonella quintana str. Toulouse thioredoxin reductase YP_032529.1 1098056 R 283165 CDS YP_032530.1 49474488 2866487 1099320..1100714 1 NC_005955.1 trk system potassium uptake protein trkH 1100714 trkH 2866487 trkH Bartonella quintana str. Toulouse trk system potassium uptake protein trkH YP_032530.1 1099320 D 283165 CDS YP_032531.1 49474489 2867081 complement(1101875..1102933) 1 NC_005955.1 lipopolysaccharide core biosynthesis mannosyltransferase lpcC 1102933 lpcC 2867081 lpcC Bartonella quintana str. Toulouse lipopolysaccharide core biosynthesis mannosyltransferase lpcC YP_032531.1 1101875 R 283165 CDS YP_032532.1 49474490 2866991 complement(1102940..1103413) 1 NC_005955.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1103413 greA 2866991 greA Bartonella quintana str. Toulouse transcription elongation factor GreA YP_032532.1 1102940 R 283165 CDS YP_032533.1 49474491 2867171 1103747..1104079 1 NC_005955.1 hypothetical protein 1104079 2867171 BQ09320 Bartonella quintana str. Toulouse hypothetical protein YP_032533.1 1103747 D 283165 CDS YP_032534.1 49474492 2867331 1104330..1106654 1 NC_005955.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1106654 uvrB 2867331 uvrB Bartonella quintana str. Toulouse excinuclease ABC subunit B YP_032534.1 1104330 D 283165 CDS YP_032535.1 49474493 2867594 1108507..1108980 1 NC_005955.1 RNA methyltransferase 1108980 2867594 BQ09340 Bartonella quintana str. Toulouse RNA methyltransferase YP_032535.1 1108507 D 283165 CDS YP_032536.1 49474494 2866813 complement(1109225..1110478) 1 NC_005955.1 poly(A) polymerase 1110478 pcnB 2866813 pcnB Bartonella quintana str. Toulouse poly(A) polymerase YP_032536.1 1109225 R 283165 CDS YP_032537.1 49474495 2867121 1110731..1111762 1 NC_005955.1 regulatory protein 1111762 2867121 BQ09360 Bartonella quintana str. Toulouse regulatory protein YP_032537.1 1110731 D 283165 CDS YP_032538.1 49474496 2867300 1111762..1112673 1 NC_005955.1 hypothetical protein 1112673 2867300 BQ09370 Bartonella quintana str. Toulouse hypothetical protein YP_032538.1 1111762 D 283165 CDS YP_032539.1 49474497 2867009 1112670..1115474 1 NC_005955.1 hypothetical protein 1115474 2867009 BQ09380 Bartonella quintana str. Toulouse hypothetical protein YP_032539.1 1112670 D 283165 CDS YP_032540.1 49474498 2866975 1115471..1117567 1 NC_005955.1 hypothetical protein 1117567 2866975 BQ09390 Bartonella quintana str. Toulouse hypothetical protein YP_032540.1 1115471 D 283165 CDS YP_032541.1 49474499 2866315 1117821..1118723 1 NC_005955.1 hypothetical protein 1118723 2866315 BQ09400 Bartonella quintana str. Toulouse hypothetical protein YP_032541.1 1117821 D 283165 CDS YP_032542.1 49474500 2867168 complement(1118823..1119731) 1 NC_005955.1 hypothetical protein 1119731 2867168 BQ09410 Bartonella quintana str. Toulouse hypothetical protein YP_032542.1 1118823 R 283165 CDS YP_032543.1 49474501 2866559 complement(1121390..1122616) 1 NC_005955.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1122616 mnmA 2866559 mnmA Bartonella quintana str. Toulouse tRNA-specific 2-thiouridylase MnmA YP_032543.1 1121390 R 283165 CDS YP_032544.1 49474502 2866992 1122930..1123205 1 NC_005955.1 hypothetical protein 1123205 2866992 BQ09440 Bartonella quintana str. Toulouse hypothetical protein YP_032544.1 1122930 D 283165 CDS YP_032545.1 49474503 2866585 complement(1123331..1123717) 1 NC_005955.1 hypothetical protein 1123717 2866585 BQ09450 Bartonella quintana str. Toulouse hypothetical protein YP_032545.1 1123331 R 283165 CDS YP_032546.1 49474504 2866713 1124285..1124986 1 NC_005955.1 cell cycle transcriptional regulator ctra 1124986 ctrA 2866713 ctrA Bartonella quintana str. Toulouse cell cycle transcriptional regulator ctra YP_032546.1 1124285 D 283165 CDS YP_032547.1 49474505 2867575 complement(1125200..1125838) 1 NC_005955.1 hypothetical protein 1125838 2867575 BQ09470 Bartonella quintana str. Toulouse hypothetical protein YP_032547.1 1125200 R 283165 CDS YP_032548.1 49474506 2866308 1126053..1126649 1 NC_005955.1 hypothetical protein 1126649 2866308 BQ09480 Bartonella quintana str. Toulouse hypothetical protein YP_032548.1 1126053 D 283165 CDS YP_032549.1 49474507 2867501 1126677..1127339 1 NC_005955.1 hypothetical protein 1127339 2867501 BQ09490 Bartonella quintana str. Toulouse hypothetical protein YP_032549.1 1126677 D 283165 CDS YP_032550.1 49474508 2866589 complement(1127599..1128717) 1 NC_005955.1 degT /dnrJ /eryC1 /strS family protein 1128717 2866589 BQ09500 Bartonella quintana str. Toulouse degT /dnrJ /eryC1 /strS family protein YP_032550.1 1127599 R 283165 CDS YP_032551.1 49474509 2867177 complement(1128769..1129725) 1 NC_005955.1 hypothetical protein 1129725 2867177 BQ09510 Bartonella quintana str. Toulouse hypothetical protein YP_032551.1 1128769 R 283165 CDS YP_032552.1 49474510 2867518 complement(1130820..1131602) 1 NC_005955.1 ABC transporter ATP-binding protein 1131602 2867518 BQ09530 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032552.1 1130820 R 283165 CDS YP_032553.1 49474511 2867165 complement(1131614..1132474) 1 NC_005955.1 oligopeptide transport ATP-binding protein 1132474 oppD 2867165 oppD Bartonella quintana str. Toulouse oligopeptide transport ATP-binding protein YP_032553.1 1131614 R 283165 CDS YP_032554.1 49474512 2867487 complement(1132467..1133396) 1 NC_005955.1 ABC transporter permease 1133396 2867487 BQ09550 Bartonella quintana str. Toulouse ABC transporter permease YP_032554.1 1132467 R 283165 CDS YP_032555.1 49474513 2867509 complement(1133399..1134472) 1 NC_005955.1 ABC transporter permease 1134472 2867509 BQ09560 Bartonella quintana str. Toulouse ABC transporter permease YP_032555.1 1133399 R 283165 CDS YP_032556.1 49474514 2866426 complement(1134563..1136200) 1 NC_005955.1 ABC transporter periplasmic oligopeptide-binding protein 1136200 2866426 BQ09570 Bartonella quintana str. Toulouse ABC transporter periplasmic oligopeptide-binding protein YP_032556.1 1134563 R 283165 CDS YP_032557.1 49474515 2866948 complement(1136614..1138239) 1 NC_005955.1 ABC transporter periplasmic oligopeptide-binding protein 1138239 2866948 BQ09580 Bartonella quintana str. Toulouse ABC transporter periplasmic oligopeptide-binding protein YP_032557.1 1136614 R 283165 CDS YP_032558.1 49474516 2866655 complement(1139596..1140222) 1 NC_005955.1 DNA-3-methyladenine glycosylase I 1140222 tag 2866655 tag Bartonella quintana str. Toulouse DNA-3-methyladenine glycosylase I YP_032558.1 1139596 R 283165 CDS YP_032559.1 49474517 2866906 complement(1140200..1141627) 1 NC_005955.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1141627 xseA 2866906 xseA Bartonella quintana str. Toulouse exodeoxyribonuclease VII large subunit YP_032559.1 1140200 R 283165 CDS YP_032560.1 49474518 2866840 complement(1142569..1143369) 1 NC_005955.1 hypothetical protein 1143369 2866840 BQ09640 Bartonella quintana str. Toulouse hypothetical protein YP_032560.1 1142569 R 283165 CDS YP_032561.1 49474519 2867484 complement(1143372..1144292) 1 NC_005955.1 hypothetical protein 1144292 2867484 BQ09650 Bartonella quintana str. Toulouse hypothetical protein YP_032561.1 1143372 R 283165 CDS YP_032562.1 49474520 2867472 complement(1144451..1145176) 1 NC_005955.1 hypothetical protein 1145176 2867472 BQ09660 Bartonella quintana str. Toulouse hypothetical protein YP_032562.1 1144451 R 283165 CDS YP_032563.1 49474521 2866793 1145895..1146641 1 NC_005955.1 electron transfer flavoprotein subunit beta 1146641 etfB 2866793 etfB Bartonella quintana str. Toulouse electron transfer flavoprotein subunit beta YP_032563.1 1145895 D 283165 CDS YP_032564.1 49474522 2866803 1146694..1147614 1 NC_005955.1 electron transfer flavoprotein subunit alpha 1147614 etfA 2866803 etfA Bartonella quintana str. Toulouse electron transfer flavoprotein subunit alpha YP_032564.1 1146694 D 283165 CDS YP_032565.1 49474523 2866362 1147618..1149276 1 NC_005955.1 electron transfer flavoprotein-ubiquinone oxidoreductase 1149276 2866362 BQ09690 Bartonella quintana str. Toulouse electron transfer flavoprotein-ubiquinone oxidoreductase YP_032565.1 1147618 D 283165 CDS YP_032566.1 49474524 2866380 complement(1150201..1151001) 1 NC_005955.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1151001 proC 2866380 proC Bartonella quintana str. Toulouse pyrroline-5-carboxylate reductase YP_032566.1 1150201 R 283165 CDS YP_032567.1 49474525 2866290 complement(1151057..1151302) 1 NC_005955.1 hypothetical protein 1151302 2866290 BQ09710 Bartonella quintana str. Toulouse hypothetical protein YP_032567.1 1151057 R 283165 CDS YP_032568.1 49474526 2867469 complement(1151409..1151777) 1 NC_005955.1 hypothetical protein 1151777 2867469 BQ09720 Bartonella quintana str. Toulouse hypothetical protein YP_032568.1 1151409 R 283165 CDS YP_032569.1 49474527 2867477 complement(1151801..1152688) 1 NC_005955.1 hypothetical protein 1152688 2867477 BQ09730 Bartonella quintana str. Toulouse hypothetical protein YP_032569.1 1151801 R 283165 CDS YP_032570.1 49474528 2866632 complement(1153602..1154687) 1 NC_005955.1 mrp protein 1154687 mrp 2866632 mrp Bartonella quintana str. Toulouse mrp protein YP_032570.1 1153602 R 283165 CDS YP_032571.1 49474529 2866570 1155264..1155398 1 NC_005955.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1155398 rpmH 2866570 rpmH Bartonella quintana str. Toulouse 50S ribosomal protein L34 YP_032571.1 1155264 D 283165 CDS YP_032572.1 49474530 2866805 1155507..1155908 1 NC_005955.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1155908 rnpA 2866805 rnpA Bartonella quintana str. Toulouse ribonuclease P YP_032572.1 1155507 D 283165 CDS YP_032573.1 49474531 2866896 1155898..1157739 1 NC_005955.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1157739 2866896 BQ09780 Bartonella quintana str. Toulouse inner membrane protein translocase component YidC YP_032573.1 1155898 D 283165 CDS YP_032574.1 49474532 2867219 1157736..1158383 1 NC_005955.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1158383 engB 2867219 engB Bartonella quintana str. Toulouse ribosome biogenesis GTP-binding protein YsxC YP_032574.1 1157736 D 283165 CDS YP_032575.1 49474533 2866359 1158531..1159223 1 NC_005955.1 glutathione S-transferase 1159223 2866359 BQ09800 Bartonella quintana str. Toulouse glutathione S-transferase YP_032575.1 1158531 D 283165 CDS YP_032576.1 49474534 2867460 1159393..1160205 1 NC_005955.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1160205 2867460 BQ09810 Bartonella quintana str. Toulouse dihydrodipicolinate reductase YP_032576.1 1159393 D 283165 CDS YP_032577.1 49474535 2867163 1160234..1160854 1 NC_005955.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1160854 gpmA 2867163 gpmA Bartonella quintana str. Toulouse phosphoglyceromutase YP_032577.1 1160234 D 283165 CDS YP_032578.1 49474536 2866863 1164333..1165538 1 NC_005955.1 omp43 precursor 1165538 2866863 BQ09890 Bartonella quintana str. Toulouse omp43 precursor YP_032578.1 1164333 D 283165 CDS YP_032579.1 49474537 2866339 complement(1166521..1167480) 1 NC_005955.1 hypothetical protein 1167480 2866339 BQ09900 Bartonella quintana str. Toulouse hypothetical protein YP_032579.1 1166521 R 283165 CDS YP_032580.1 49474538 2867535 complement(1167607..1167981) 1 NC_005955.1 hypothetical protein 1167981 2867535 BQ09910 Bartonella quintana str. Toulouse hypothetical protein YP_032580.1 1167607 R 283165 CDS YP_032581.1 49474539 2866891 complement(1168794..1169069) 1 NC_005955.1 hypothetical protein 1169069 2866891 BQ09920 Bartonella quintana str. Toulouse hypothetical protein YP_032581.1 1168794 R 283165 CDS YP_032582.1 49474540 2866913 complement(1170990..1172075) 1 NC_005955.1 hypothetical protein 1172075 2866913 BQ09930 Bartonella quintana str. Toulouse hypothetical protein YP_032582.1 1170990 R 283165 CDS YP_032583.1 49474541 2866915 1179507..1179899 1 NC_005955.1 transcriptional regulator 1179899 2866915 BQ10010 Bartonella quintana str. Toulouse transcriptional regulator YP_032583.1 1179507 D 283165 CDS YP_032584.1 49474542 2867183 1180055..1181149 1 NC_005955.1 multidrug resistance protein vceA 1181149 vceA 2867183 vceA Bartonella quintana str. Toulouse multidrug resistance protein vceA YP_032584.1 1180055 D 283165 CDS YP_032585.1 49474543 2867098 1181173..1182744 1 NC_005955.1 multidrug resistance protein vceB 1182744 vceB 2867098 vceB Bartonella quintana str. Toulouse multidrug resistance protein vceB YP_032585.1 1181173 D 283165 CDS YP_032586.1 49474544 2866333 complement(1183127..1183705) 1 NC_005955.1 acetyltransferase 1183705 2866333 BQ10040 Bartonella quintana str. Toulouse acetyltransferase YP_032586.1 1183127 R 283165 CDS YP_032587.1 49474545 2866337 complement(1183759..1184892) 1 NC_005955.1 ornithine decarboxylase 1184892 odc 2866337 odc Bartonella quintana str. Toulouse ornithine decarboxylase YP_032587.1 1183759 R 283165 CDS YP_032588.1 49474546 2867313 complement(1184927..1185169) 1 NC_005955.1 hypothetical protein 1185169 2867313 BQ10060 Bartonella quintana str. Toulouse hypothetical protein YP_032588.1 1184927 R 283165 CDS YP_032589.1 49474547 2866907 complement(1186001..1186915) 1 NC_005955.1 hypothetical protein 1186915 2866907 BQ10070 Bartonella quintana str. Toulouse hypothetical protein YP_032589.1 1186001 R 283165 CDS YP_032590.1 49474548 2867413 complement(1187693..1188523) 1 NC_005955.1 ferredoxin-NADP reductase 1188523 fpr 2867413 fpr Bartonella quintana str. Toulouse ferredoxin-NADP reductase YP_032590.1 1187693 R 283165 CDS YP_032591.1 49474549 2866677 1189167..1190285 1 NC_005955.1 alanine racemase 1190285 alr 2866677 alr Bartonella quintana str. Toulouse alanine racemase YP_032591.1 1189167 D 283165 CDS YP_032592.1 49474550 2867118 complement(1191537..1194332) 1 NC_005955.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 1194332 gcvP 2867118 gcvP Bartonella quintana str. Toulouse glycine dehydrogenase YP_032592.1 1191537 R 283165 CDS YP_032593.1 49474551 2866374 complement(1194338..1194706) 1 NC_005955.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 1194706 gcvH 2866374 gcvH Bartonella quintana str. Toulouse glycine cleavage system protein H YP_032593.1 1194338 R 283165 CDS YP_032594.1 49474552 2867114 complement(1194715..1195833) 1 NC_005955.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1195833 gcvT 2867114 gcvT Bartonella quintana str. Toulouse glycine cleavage system aminomethyltransferase T YP_032594.1 1194715 R 283165 CDS YP_032595.1 49474553 2866293 1196549..1197211 1 NC_005955.1 ATP-dependent protease lon 1197211 lon2 2866293 lon2 Bartonella quintana str. Toulouse ATP-dependent protease lon YP_032595.1 1196549 D 283165 CDS YP_032596.1 49474554 2867091 1197234..1197431 1 NC_005955.1 hypothetical protein 1197431 2867091 BQ10150 Bartonella quintana str. Toulouse hypothetical protein YP_032596.1 1197234 D 283165 CDS YP_032597.1 49474555 2867304 1198870..1199901 1 NC_005955.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1199901 asd 2867304 asd Bartonella quintana str. Toulouse aspartate-semialdehyde dehydrogenase YP_032597.1 1198870 D 283165 CDS YP_032598.1 49474556 2867189 complement(1199989..1200615) 1 NC_005955.1 hypothetical protein 1200615 2867189 BQ10180 Bartonella quintana str. Toulouse hypothetical protein YP_032598.1 1199989 R 283165 CDS YP_032599.1 49474557 2867113 complement(1203616..1204083) 1 NC_005955.1 nodulation protein n 1204083 nodN 2867113 nodN Bartonella quintana str. Toulouse nodulation protein n YP_032599.1 1203616 R 283165 CDS YP_032600.1 49474558 2867528 1204252..1205589 1 NC_005955.1 hypothetical protein 1205589 2867528 BQ10230 Bartonella quintana str. Toulouse hypothetical protein YP_032600.1 1204252 D 283165 CDS YP_032601.1 49474559 2867529 complement(1206397..1206771) 1 NC_005955.1 hypothetical protein 1206771 2867529 BQ10250 Bartonella quintana str. Toulouse hypothetical protein YP_032601.1 1206397 R 283165 CDS YP_032602.1 49474560 2866715 1208286..1209026 1 NC_005955.1 hypothetical protein 1209026 2866715 BQ10260 Bartonella quintana str. Toulouse hypothetical protein YP_032602.1 1208286 D 283165 CDS YP_032603.1 49474561 2867355 complement(1210540..1213575) 1 NC_005955.1 hypothetical protein 1213575 2867355 BQ10280 Bartonella quintana str. Toulouse hypothetical protein YP_032603.1 1210540 R 283165 CDS YP_032604.1 49474562 2866678 complement(1214203..1219821) 1 NC_005955.1 surface protein 1219821 2866678 BQ10290 Bartonella quintana str. Toulouse surface protein YP_032604.1 1214203 R 283165 CDS YP_032605.1 49474563 2867034 1220060..1220959 1 NC_005955.1 ferric anguibactin-binding protein 1220959 fatB 2867034 fatB Bartonella quintana str. Toulouse ferric anguibactin-binding protein YP_032605.1 1220060 D 283165 CDS YP_032606.1 49474564 2867031 1221059..1222015 1 NC_005955.1 ferric anguibactin transport system permease 1222015 fatD 2867031 fatD Bartonella quintana str. Toulouse ferric anguibactin transport system permease YP_032606.1 1221059 D 283165 CDS YP_032607.1 49474565 2867033 1222083..1222958 1 NC_005955.1 ferric anguibactin transport system permease 1222958 fatC 2867033 fatC Bartonella quintana str. Toulouse ferric anguibactin transport system permease YP_032607.1 1222083 D 283165 CDS YP_032608.1 49474566 2867411 1222955..1223713 1 NC_005955.1 Iron compound ABC transporter 1223713 ceuD 2867411 ceuD Bartonella quintana str. Toulouse Iron compound ABC transporter YP_032608.1 1222955 D 283165 CDS YP_032609.1 49474567 2866625 complement(1224781..1225785) 1 NC_005955.1 hypothetical protein 1225785 2866625 BQ10350 Bartonella quintana str. Toulouse hypothetical protein YP_032609.1 1224781 R 283165 CDS YP_032610.1 49474568 2866637 1229054..1231357 1 NC_005955.1 hypothetical protein 1231357 2866637 BQ10380 Bartonella quintana str. Toulouse hypothetical protein YP_032610.1 1229054 D 283165 CDS YP_032611.1 49474569 2867380 1235401..1238667 1 NC_005955.1 hypothetical protein 1238667 2867380 BQ10410 Bartonella quintana str. Toulouse hypothetical protein YP_032611.1 1235401 D 283165 CDS YP_032612.1 49474570 2866645 complement(1241044..1241445) 1 NC_005955.1 hypothetical protein 1241445 2866645 BQ10440 Bartonella quintana str. Toulouse hypothetical protein YP_032612.1 1241044 R 283165 CDS YP_032613.1 49474571 2867376 1242629..1243012 1 NC_005955.1 hypothetical protein 1243012 2867376 BQ10450 Bartonella quintana str. Toulouse hypothetical protein YP_032613.1 1242629 D 283165 CDS YP_032614.1 49474572 2866475 1244403..1244732 1 NC_005955.1 hypothetical protein 1244732 2866475 BQ10460 Bartonella quintana str. Toulouse hypothetical protein YP_032614.1 1244403 D 283165 CDS YP_032615.1 49474573 2867450 complement(1244980..1245948) 1 NC_005955.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 1245948 ribF 2867450 ribF Bartonella quintana str. Toulouse bifunctional riboflavin kinase/FMN adenylyltransferase YP_032615.1 1244980 R 283165 CDS YP_032616.1 49474574 2866378 complement(1245981..1246826) 1 NC_005955.1 hypothetical protein 1246826 2866378 BQ10480 Bartonella quintana str. Toulouse hypothetical protein YP_032616.1 1245981 R 283165 CDS YP_032617.1 49474575 2867383 complement(1248573..1248896) 1 NC_005955.1 hypothetical protein 1248896 2867383 BQ10500 Bartonella quintana str. Toulouse hypothetical protein YP_032617.1 1248573 R 283165 CDS YP_032618.1 49474576 2866467 complement(1249136..1249339) 1 NC_005955.1 hypothetical protein 1249339 2866467 BQ10510 Bartonella quintana str. Toulouse hypothetical protein YP_032618.1 1249136 R 283165 CDS YP_032619.1 49474577 2866530 complement(1249340..1250083) 1 NC_005955.1 hypothetical protein 1250083 2866530 BQ10520 Bartonella quintana str. Toulouse hypothetical protein YP_032619.1 1249340 R 283165 CDS YP_032620.1 49474578 2866954 1250432..1250746 1 NC_005955.1 virB2 protein 1250746 virB2 2866954 virB2 Bartonella quintana str. Toulouse virB2 protein YP_032620.1 1250432 D 283165 CDS YP_032621.1 49474579 2866936 1250747..1251058 1 NC_005955.1 virB3 protein 1251058 virB3 2866936 virB3 Bartonella quintana str. Toulouse virB3 protein YP_032621.1 1250747 D 283165 CDS YP_032622.1 49474580 2866930 1251064..1253418 1 NC_005955.1 virB4 protein 1253418 virB4 2866930 virB4 Bartonella quintana str. Toulouse virB4 protein YP_032622.1 1251064 D 283165 CDS YP_032623.1 49474581 2866708 1253415..1253861 1 NC_005955.1 hypothetical protein 1253861 2866708 BQ10560 Bartonella quintana str. Toulouse hypothetical protein YP_032623.1 1253415 D 283165 CDS YP_032624.1 49474582 2866931 1253848..1254813 1 NC_005955.1 virB6 protein 1254813 virB6 2866931 virB6 Bartonella quintana str. Toulouse virB6 protein YP_032624.1 1253848 D 283165 CDS YP_032625.1 49474583 2866394 1255047..1255361 1 NC_005955.1 hypothetical protein 1255361 2866394 BQ10580 Bartonella quintana str. Toulouse hypothetical protein YP_032625.1 1255047 D 283165 CDS YP_032626.1 49474584 2866924 1255351..1256019 1 NC_005955.1 virB8 protein 1256019 virB8 2866924 virB8 Bartonella quintana str. Toulouse virB8 protein YP_032626.1 1255351 D 283165 CDS YP_032627.1 49474585 2866919 1256019..1256885 1 NC_005955.1 virB9 protein 1256885 virB9 2866919 virB9 Bartonella quintana str. Toulouse virB9 protein YP_032627.1 1256019 D 283165 CDS YP_032628.1 49474586 2867095 1256875..1258032 1 NC_005955.1 virB10 protein 1258032 virB10 2867095 virB10 Bartonella quintana str. Toulouse virB10 protein YP_032628.1 1256875 D 283165 CDS YP_032629.1 49474587 2867096 1258029..1259099 1 NC_005955.1 virB11 protein 1259099 virB11 2867096 virB11 Bartonella quintana str. Toulouse virB11 protein YP_032629.1 1258029 D 283165 CDS YP_032630.1 49474588 2866612 1261086..1263005 1 NC_005955.1 VirD4 family; conjugal transfer protein TraG 1263005 traG 2866612 traG Bartonella quintana str. Toulouse conjugal transfer protein TraG YP_032630.1 1261086 D 283165 CDS YP_032631.1 49474589 2866656 1263630..1265231 1 NC_005955.1 cell filamentation protein 1265231 2866656 BQ10650 Bartonella quintana str. Toulouse cell filamentation protein YP_032631.1 1263630 D 283165 CDS YP_032632.1 49474590 2866571 1265556..1267058 1 NC_005955.1 hypothetical protein 1267058 2866571 BQ10660 Bartonella quintana str. Toulouse hypothetical protein YP_032632.1 1265556 D 283165 CDS YP_032633.1 49474591 2866552 1267412..1269157 1 NC_005955.1 hypothetical protein 1269157 2866552 BQ10670 Bartonella quintana str. Toulouse hypothetical protein YP_032633.1 1267412 D 283165 CDS YP_032634.1 49474592 2867377 1269465..1271246 1 NC_005955.1 hypothetical protein 1271246 2867377 BQ10680 Bartonella quintana str. Toulouse hypothetical protein YP_032634.1 1269465 D 283165 CDS YP_032635.1 49474593 2866827 1272665..1274236 1 NC_005955.1 virulence factor mviN-like protein 1274236 mviN 2866827 mviN Bartonella quintana str. Toulouse virulence factor mviN-like protein YP_032635.1 1272665 D 283165 CDS YP_032636.1 49474594 2866917 1274330..1275400 1 NC_005955.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1275400 trpS 2866917 trpS Bartonella quintana str. Toulouse tryptophanyl-tRNA synthetase YP_032636.1 1274330 D 283165 CDS YP_032637.1 49474595 2867332 1275462..1275953 1 NC_005955.1 hypothetical protein 1275953 2867332 BQ10710 Bartonella quintana str. Toulouse hypothetical protein YP_032637.1 1275462 D 283165 CDS YP_032638.1 49474596 2866693 1276010..1276588 1 NC_005955.1 hypothetical protein 1276588 2866693 BQ10720 Bartonella quintana str. Toulouse hypothetical protein YP_032638.1 1276010 D 283165 CDS YP_032639.1 49474597 2866615 complement(1277281..1278924) 1 NC_005955.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 1278924 groEL 2866615 groEL Bartonella quintana str. Toulouse molecular chaperone GroEL YP_032639.1 1277281 R 283165 CDS YP_032640.1 49474598 2866616 complement(1278985..1279281) 1 NC_005955.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1279281 groES 2866616 groES Bartonella quintana str. Toulouse co-chaperonin GroES YP_032640.1 1278985 R 283165 CDS YP_032641.1 49474599 2867433 1279505..1280893 1 NC_005955.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1280893 fumC 2867433 fumC Bartonella quintana str. Toulouse fumarate hydratase YP_032641.1 1279505 D 283165 CDS YP_032642.1 49474600 2866349 complement(1281572..1283200) 1 NC_005955.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 1283200 pgm 2866349 pgm Bartonella quintana str. Toulouse phosphoglucomutase YP_032642.1 1281572 R 283165 CDS YP_032643.1 49474601 2867335 1283399..1283923 1 NC_005955.1 hypothetical protein 1283923 2867335 BQ10800 Bartonella quintana str. Toulouse hypothetical protein YP_032643.1 1283399 D 283165 CDS YP_032644.1 49474602 2867302 complement(1285654..1287150) 1 NC_005955.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1287150 hisS 2867302 hisS Bartonella quintana str. Toulouse histidyl-tRNA synthetase YP_032644.1 1285654 R 283165 CDS YP_032645.1 49474603 2867349 complement(1288009..1288854) 1 NC_005955.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1288854 pyrF 2867349 pyrF Bartonella quintana str. Toulouse orotidine 5'-phosphate decarboxylase YP_032645.1 1288009 R 283165 CDS YP_032646.1 49474604 2867357 complement(1289704..1290789) 1 NC_005955.1 hypothetical protein 1290789 2867357 BQ10850 Bartonella quintana str. Toulouse hypothetical protein YP_032646.1 1289704 R 283165 CDS YP_032647.1 49474605 2866436 1298350..1300356 1 NC_005955.1 hypothetical protein 1300356 2866436 BQ10930 Bartonella quintana str. Toulouse hypothetical protein YP_032647.1 1298350 D 283165 CDS YP_032648.1 49474606 2866733 complement(1301114..1302571) 1 NC_005955.1 hypothetical protein 1302571 2866733 BQ10950 Bartonella quintana str. Toulouse hypothetical protein YP_032648.1 1301114 R 283165 CDS YP_032649.1 49474607 2867577 complement(1302825..1303319) 1 NC_005955.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1303319 sigH 2867577 sigH Bartonella quintana str. Toulouse RNA polymerase sigma factor YP_032649.1 1302825 R 283165 CDS YP_032650.1 49474608 2867326 complement(1303328..1303531) 1 NC_005955.1 hypothetical protein 1303531 2867326 BQ10970 Bartonella quintana str. Toulouse hypothetical protein YP_032650.1 1303328 R 283165 CDS YP_032651.1 49474609 2867324 1303700..1304494 1 NC_005955.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 1304494 2867324 BQ10980 Bartonella quintana str. Toulouse two-component response regulator YP_032651.1 1303700 D 283165 CDS YP_032652.1 49474610 2867329 1304515..1305528 1 NC_005955.1 sensory transduction histidine kinase 1305528 2867329 BQ10990 Bartonella quintana str. Toulouse sensory transduction histidine kinase YP_032652.1 1304515 D 283165 CDS YP_032653.1 49474611 2867341 complement(1305771..1306511) 1 NC_005955.1 hypothetical protein 1306511 2867341 BQ11000 Bartonella quintana str. Toulouse hypothetical protein YP_032653.1 1305771 R 283165 CDS YP_032654.1 49474612 2867339 complement(1306737..1306997) 1 NC_005955.1 hypothetical protein 1306997 2867339 BQ11010 Bartonella quintana str. Toulouse hypothetical protein YP_032654.1 1306737 R 283165 CDS YP_032655.1 49474613 2867039 1307339..1308280 1 NC_005955.1 hypothetical protein 1308280 fdhE 2867039 fdhE Bartonella quintana str. Toulouse hypothetical protein YP_032655.1 1307339 D 283165 CDS YP_032656.1 49474614 2866554 complement(1308956..1309402) 1 NC_005955.1 hypothetical protein 1309402 2866554 BQ11030 Bartonella quintana str. Toulouse hypothetical protein YP_032656.1 1308956 R 283165 CDS YP_032657.1 49474615 2867343 1310858..1311226 1 NC_005955.1 hypothetical protein 1311226 2867343 BQ11040 Bartonella quintana str. Toulouse hypothetical protein YP_032657.1 1310858 D 283165 CDS YP_032658.1 49474616 2866564 1311277..1311729 1 NC_005955.1 hypothetical protein 1311729 2866564 BQ11050 Bartonella quintana str. Toulouse hypothetical protein YP_032658.1 1311277 D 283165 CDS YP_032659.1 49474617 2866694 complement(1312686..1313657) 1 NC_005955.1 hypothetical protein 1313657 2866694 BQ11060 Bartonella quintana str. Toulouse hypothetical protein YP_032659.1 1312686 R 283165 CDS YP_032660.1 49474618 2866568 complement(1313654..1314778) 1 NC_005955.1 hypothetical protein 1314778 2866568 BQ11070 Bartonella quintana str. Toulouse hypothetical protein YP_032660.1 1313654 R 283165 CDS YP_032661.1 49474619 2866710 complement(1314775..1315233) 1 NC_005955.1 hypothetical protein 1315233 2866710 BQ11080 Bartonella quintana str. Toulouse hypothetical protein YP_032661.1 1314775 R 283165 CDS YP_032662.1 49474620 2866686 complement(1315406..1316866) 1 NC_005955.1 hypothetical protein 1316866 2866686 BQ11090 Bartonella quintana str. Toulouse hypothetical protein YP_032662.1 1315406 R 283165 CDS YP_032663.1 49474621 2866671 complement(1317135..1317830) 1 NC_005955.1 hypothetical protein 1317830 2866671 BQ11100 Bartonella quintana str. Toulouse hypothetical protein YP_032663.1 1317135 R 283165 CDS YP_032664.1 49474622 2866725 complement(1317988..1319106) 1 NC_005955.1 hypothetical protein 1319106 2866725 BQ11110 Bartonella quintana str. Toulouse hypothetical protein YP_032664.1 1317988 R 283165 CDS YP_032665.1 49474623 2866697 complement(1319525..1320319) 1 NC_005955.1 hypothetical protein 1320319 2866697 BQ11120 Bartonella quintana str. Toulouse hypothetical protein YP_032665.1 1319525 R 283165 CDS YP_032666.1 49474624 2866617 complement(1320416..1322260) 1 NC_005955.1 hypothetical protein 1322260 2866617 BQ11130 Bartonella quintana str. Toulouse hypothetical protein YP_032666.1 1320416 R 283165 CDS YP_032667.1 49474625 2866695 complement(1322245..1323453) 1 NC_005955.1 phage related protein 1323453 2866695 BQ11140 Bartonella quintana str. Toulouse phage related protein YP_032667.1 1322245 R 283165 CDS YP_032668.1 49474626 2866614 complement(1324424..1324738) 1 NC_005955.1 hypothetical protein 1324738 2866614 BQ11160 Bartonella quintana str. Toulouse hypothetical protein YP_032668.1 1324424 R 283165 CDS YP_032669.1 49474627 2866522 complement(1325274..1327913) 1 NC_005955.1 ATP-dependent Clp protease, ATP-binding subunit clpB 1327913 clpB 2866522 clpB Bartonella quintana str. Toulouse ATP-dependent Clp protease, ATP-binding subunit clpB YP_032669.1 1325274 R 283165 CDS YP_032670.1 49474628 2866460 complement(1328557..1328859) 1 NC_005955.1 zinc-binding protein 1328859 2866460 BQ11180 Bartonella quintana str. Toulouse zinc-binding protein YP_032670.1 1328557 R 283165 CDS YP_032671.1 49474629 2866468 complement(1328886..1329569) 1 NC_005955.1 septum formation maf protein 1329569 maf-2 2866468 maf-2 Bartonella quintana str. Toulouse septum formation maf protein YP_032671.1 1328886 R 283165 CDS YP_032672.1 49474630 2866383 complement(1329793..1330011) 1 NC_005955.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1330011 infA 2866383 infA Bartonella quintana str. Toulouse translation initiation factor IF-1 YP_032672.1 1329793 R 283165 CDS YP_032673.1 49474631 2866500 complement(1331288..1331869) 1 NC_005955.1 hypothetical protein 1331869 2866500 BQ11210 Bartonella quintana str. Toulouse hypothetical protein YP_032673.1 1331288 R 283165 CDS YP_032674.1 49474632 2867213 complement(1332542..1333132) 1 NC_005955.1 hypothetical protein 1333132 2867213 BQ11240 Bartonella quintana str. Toulouse hypothetical protein YP_032674.1 1332542 R 283165 CDS YP_032675.1 49474633 2866833 1335237..1335734 1 NC_005955.1 phosphoribosylaminoimidazole carboxylase I 1335734 purE 2866833 purE Bartonella quintana str. Toulouse phosphoribosylaminoimidazole carboxylase I YP_032675.1 1335237 D 283165 CDS YP_032676.1 49474634 2867055 1335753..1336931 1 NC_005955.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1336931 purK 2867055 purK Bartonella quintana str. Toulouse phosphoribosylaminoimidazole carboxylase ATPase subunit YP_032676.1 1335753 D 283165 CDS YP_032677.1 49474635 2867538 1337002..1337394 1 NC_005955.1 hypothetical protein 1337394 2867538 BQ11300 Bartonella quintana str. Toulouse hypothetical protein YP_032677.1 1337002 D 283165 CDS YP_032678.1 49474636 2866555 1338147..1338272 1 NC_005955.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1338272 rpmJ 2866555 rpmJ Bartonella quintana str. Toulouse 50S ribosomal protein L36 YP_032678.1 1338147 D 283165 CDS YP_032679.1 49474637 2867201 1338387..1339184 1 NC_005955.1 signal peptide protein 1339184 2867201 BQ11320 Bartonella quintana str. Toulouse signal peptide protein YP_032679.1 1338387 D 283165 CDS YP_032680.1 49474638 2867443 1340170..1340856 1 NC_005955.1 hypothetical protein 1340856 2867443 BQ11340 Bartonella quintana str. Toulouse hypothetical protein YP_032680.1 1340170 D 283165 CDS YP_032681.1 49474639 2866364 1340875..1341696 1 NC_005955.1 hypothetical protein 1341696 2866364 BQ11350 Bartonella quintana str. Toulouse hypothetical protein YP_032681.1 1340875 D 283165 CDS YP_032682.1 49474640 2867474 1342368..1342598 1 NC_005955.1 hypothetical protein 1342598 2867474 BQ11380 Bartonella quintana str. Toulouse hypothetical protein YP_032682.1 1342368 D 283165 CDS YP_032683.1 49474641 2866515 1342770..1344065 1 NC_005955.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1344065 murA 2866515 murA Bartonella quintana str. Toulouse UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_032683.1 1342770 D 283165 CDS YP_032684.1 49474642 2867492 complement(1344169..1344837) 1 NC_005955.1 phage related protein 1344837 2867492 BQ11400 Bartonella quintana str. Toulouse phage related protein YP_032684.1 1344169 R 283165 CDS YP_032685.1 49474643 2867480 complement(1345458..1345700) 1 NC_005955.1 hypothetical protein 1345700 2867480 BQ11410 Bartonella quintana str. Toulouse hypothetical protein YP_032685.1 1345458 R 283165 CDS YP_032686.1 49474644 2867507 complement(1346037..1346216) 1 NC_005955.1 hypothetical protein 1346216 2867507 BQ11420 Bartonella quintana str. Toulouse hypothetical protein YP_032686.1 1346037 R 283165 CDS YP_032687.1 49474645 2867499 complement(1346613..1346810) 1 NC_005955.1 hypothetical protein 1346810 2867499 BQ11430 Bartonella quintana str. Toulouse hypothetical protein YP_032687.1 1346613 R 283165 CDS YP_032688.1 49474646 2866967 complement(1346817..1347206) 1 NC_005955.1 hypothetical protein 1347206 2866967 BQ11450 Bartonella quintana str. Toulouse hypothetical protein YP_032688.1 1346817 R 283165 CDS YP_032689.1 49474647 2867547 complement(1347527..1347838) 1 NC_005955.1 hypothetical protein 1347838 2867547 BQ11460 Bartonella quintana str. Toulouse hypothetical protein YP_032689.1 1347527 R 283165 CDS YP_032690.1 49474648 2866985 1348292..1349290 1 NC_005955.1 hypothetical protein 1349290 2866985 BQ11480 Bartonella quintana str. Toulouse hypothetical protein YP_032690.1 1348292 D 283165 CDS YP_032691.1 49474649 2867256 1349292..1349990 1 NC_005955.1 hypothetical protein 1349990 2867256 BQ11490 Bartonella quintana str. Toulouse hypothetical protein YP_032691.1 1349292 D 283165 CDS YP_032692.1 49474650 2867115 1350231..1352591 1 NC_005955.1 phage related protein 1352591 2867115 BQ11500 Bartonella quintana str. Toulouse phage related protein YP_032692.1 1350231 D 283165 CDS YP_032693.1 49474651 2867564 1352717..1353313 1 NC_005955.1 hypothetical protein 1353313 2867564 BQ11510 Bartonella quintana str. Toulouse hypothetical protein YP_032693.1 1352717 D 283165 CDS YP_032694.1 49474652 2867583 1353910..1354395 1 NC_005955.1 hypothetical protein 1354395 2867583 BQ11520 Bartonella quintana str. Toulouse hypothetical protein YP_032694.1 1353910 D 283165 CDS YP_032695.1 49474653 2867598 1355553..1355870 1 NC_005955.1 hypothetical protein 1355870 2867598 BQ11530 Bartonella quintana str. Toulouse hypothetical protein YP_032695.1 1355553 D 283165 CDS YP_032696.1 49474654 2866421 1357813..1358361 1 NC_005955.1 hypothetical protein 1358361 2866421 BQ11560 Bartonella quintana str. Toulouse hypothetical protein YP_032696.1 1357813 D 283165 CDS YP_032697.1 49474655 2867367 1361316..1362263 1 NC_005955.1 intracellular effector 1362263 yopP 2867367 yopP Bartonella quintana str. Toulouse intracellular effector YP_032697.1 1361316 D 283165 CDS YP_032698.1 49474656 2866446 1363748..1364410 1 NC_005955.1 phage related lysozyme 1364410 2866446 BQ11590 Bartonella quintana str. Toulouse phage related lysozyme YP_032698.1 1363748 D 283165 CDS YP_032699.1 49474657 2866321 1368247..1368855 1 NC_005955.1 hypothetical protein 1368855 2866321 BQ11640 Bartonella quintana str. Toulouse hypothetical protein YP_032699.1 1368247 D 283165 CDS YP_032700.1 49474658 2866287 1368868..1369440 1 NC_005955.1 hypothetical protein 1369440 2866287 BQ11650 Bartonella quintana str. Toulouse hypothetical protein YP_032700.1 1368868 D 283165 CDS YP_032701.1 49474659 2867552 1371141..1371965 1 NC_005955.1 hypothetical protein 1371965 2867552 BQ11660 Bartonella quintana str. Toulouse hypothetical protein YP_032701.1 1371141 D 283165 CDS YP_032702.1 49474660 2866705 1372224..1372781 1 NC_005955.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1372781 dut 2866705 dut Bartonella quintana str. Toulouse deoxyuridine 5'-triphosphate nucleotidohydrolase YP_032702.1 1372224 D 283165 CDS YP_032703.1 49474661 2867479 complement(1373732..1374214) 1 NC_005955.1 biopolymer transport exbD protein 1374214 exbD 2867479 exbD Bartonella quintana str. Toulouse biopolymer transport exbD protein YP_032703.1 1373732 R 283165 CDS YP_032704.1 49474662 2866739 complement(1374211..1375053) 1 NC_005955.1 biopolymer transport exbB protein 1375053 exbB 2866739 exbB Bartonella quintana str. Toulouse biopolymer transport exbB protein YP_032704.1 1374211 R 283165 CDS YP_032705.1 49474663 2866451 1375539..1375865 1 NC_005955.1 hypothetical protein 1375865 2866451 BQ11720 Bartonella quintana str. Toulouse hypothetical protein YP_032705.1 1375539 D 283165 CDS YP_032706.1 49474664 2866437 1375869..1376306 1 NC_005955.1 hypothetical protein 1376306 2866437 BQ11730 Bartonella quintana str. Toulouse hypothetical protein YP_032706.1 1375869 D 283165 CDS YP_032707.1 49474665 2866668 complement(1376646..1378025) 1 NC_005955.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1378025 glmM 2866668 glmM Bartonella quintana str. Toulouse phosphoglucosamine mutase YP_032707.1 1376646 R 283165 CDS YP_032708.1 49474666 2867414 complement(1378489..1380642) 1 NC_005955.1 cell division protein ftsH 1380642 ftsH 2867414 ftsH Bartonella quintana str. Toulouse cell division protein ftsH YP_032708.1 1378489 R 283165 CDS YP_032709.1 49474667 2866921 complement(1380755..1382185) 1 NC_005955.1 hypothetical protein 1382185 2866921 BQ11760 Bartonella quintana str. Toulouse hypothetical protein YP_032709.1 1380755 R 283165 CDS YP_032710.1 49474668 2867606 complement(1383331..1383849) 1 NC_005955.1 peptidoglycan-associated lipoprotein 1383849 pal 2867606 pal Bartonella quintana str. Toulouse peptidoglycan-associated lipoprotein YP_032710.1 1383331 R 283165 CDS YP_032711.1 49474669 2867311 complement(1384061..1384750) 1 NC_005955.1 hypothetical protein 1384750 2867311 BQ11780 Bartonella quintana str. Toulouse hypothetical protein YP_032711.1 1384061 R 283165 CDS YP_032712.1 49474670 2866344 1385145..1385891 1 NC_005955.1 hypothetical protein 1385891 2866344 BQ11790 Bartonella quintana str. Toulouse hypothetical protein YP_032712.1 1385145 D 283165 CDS YP_032713.1 49474671 2866758 complement(1389474..1390796) 1 NC_005955.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1390796 tolB 2866758 tolB Bartonella quintana str. Toulouse translocation protein TolB YP_032713.1 1389474 R 283165 CDS YP_032714.1 49474672 2866754 complement(1390841..1392019) 1 NC_005955.1 tolA protein 1392019 tolA 2866754 tolA Bartonella quintana str. Toulouse tolA protein YP_032714.1 1390841 R 283165 CDS YP_032715.1 49474673 2866782 complement(1392097..1392549) 1 NC_005955.1 tolR protein 1392549 tolR 2866782 tolR Bartonella quintana str. Toulouse tolR protein YP_032715.1 1392097 R 283165 CDS YP_032716.1 49474674 2866781 complement(1392562..1393275) 1 NC_005955.1 inner membrane tolQ protein 1393275 tolQ 2866781 tolQ Bartonella quintana str. Toulouse inner membrane tolQ protein YP_032716.1 1392562 R 283165 CDS YP_032717.1 49474675 2866965 complement(1393419..1393859) 1 NC_005955.1 hypothetical protein 1393859 2866965 BQ11860 Bartonella quintana str. Toulouse hypothetical protein YP_032717.1 1393419 R 283165 CDS YP_032718.1 49474676 2866269 complement(1393852..1394937) 1 NC_005955.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1394937 ruvB 2866269 ruvB Bartonella quintana str. Toulouse Holliday junction DNA helicase RuvB YP_032718.1 1393852 R 283165 CDS YP_032719.1 49474677 2867553 complement(1394960..1395577) 1 NC_005955.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1395577 ruvA 2867553 ruvA Bartonella quintana str. Toulouse Holliday junction DNA helicase RuvA YP_032719.1 1394960 R 283165 CDS YP_032720.1 49474678 2866663 complement(1395574..1396083) 1 NC_005955.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1396083 ruvC 2866663 ruvC Bartonella quintana str. Toulouse Holliday junction resolvase YP_032720.1 1395574 R 283165 CDS YP_032721.1 49474679 2866939 complement(1396496..1397014) 1 NC_005955.1 hypothetical protein 1397014 2866939 BQ11900 Bartonella quintana str. Toulouse hypothetical protein YP_032721.1 1396496 R 283165 CDS YP_032722.1 49474680 2867574 complement(1397182..1398324) 1 NC_005955.1 opgC protein 1398324 opgC 2867574 opgC Bartonella quintana str. Toulouse opgC protein YP_032722.1 1397182 R 283165 CDS YP_032723.1 49474681 2866596 1398441..1399103 1 NC_005955.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1399103 thiE2 2866596 thiE2 Bartonella quintana str. Toulouse thiamine-phosphate pyrophosphorylase YP_032723.1 1398441 D 283165 CDS YP_032724.1 49474682 2866934 1400242..1401285 1 NC_005955.1 hypothetical protein 1401285 2866934 BQ11930 Bartonella quintana str. Toulouse hypothetical protein YP_032724.1 1400242 D 283165 CDS YP_032725.1 49474683 2866513 1401536..1402108 1 NC_005955.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1402108 efp 2866513 efp Bartonella quintana str. Toulouse elongation factor P YP_032725.1 1401536 D 283165 CDS YP_032726.1 49474684 2866779 1402124..1402915 1 NC_005955.1 extragenic suppressor protein suhb 1402915 suhB 2866779 suhB Bartonella quintana str. Toulouse extragenic suppressor protein suhb YP_032726.1 1402124 D 283165 CDS YP_032727.1 49474685 2867551 complement(1403019..1404809) 1 NC_005955.1 ABC transporter ATP-binding protein 1404809 2867551 BQ11960 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032727.1 1403019 R 283165 CDS YP_032728.1 49474686 2866510 1404996..1405217 1 NC_005955.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1405217 rpmE 2866510 rpmE Bartonella quintana str. Toulouse 50S ribosomal protein L31 YP_032728.1 1404996 D 283165 CDS YP_032729.1 49474687 2867387 complement(1405511..1406542) 1 NC_005955.1 fructose-bisphosphate aldolase 1406542 fbaB 2867387 fbaB Bartonella quintana str. Toulouse fructose-bisphosphate aldolase YP_032729.1 1405511 R 283165 CDS YP_032730.1 49474688 2867045 complement(1406621..1407814) 1 NC_005955.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1407814 pgk 2867045 pgk Bartonella quintana str. Toulouse phosphoglycerate kinase YP_032730.1 1406621 R 283165 CDS YP_032731.1 49474689 2866371 complement(1408161..1409183) 1 NC_005955.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1409183 gap 2866371 gap Bartonella quintana str. Toulouse glyceraldehyde-3-phosphate dehydrogenase YP_032731.1 1408161 R 283165 CDS YP_032732.1 49474690 2867444 complement(1409352..1411358) 1 NC_005955.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1411358 tktA 2867444 tktA Bartonella quintana str. Toulouse transketolase YP_032732.1 1409352 R 283165 CDS YP_032733.1 49474691 2867087 1411685..1411960 1 NC_005955.1 hypothetical protein 1411960 2867087 BQ12030 Bartonella quintana str. Toulouse hypothetical protein YP_032733.1 1411685 D 283165 CDS YP_032734.1 49474692 2867099 1411973..1412350 1 NC_005955.1 hypothetical protein 1412350 2867099 BQ12040 Bartonella quintana str. Toulouse hypothetical protein YP_032734.1 1411973 D 283165 CDS YP_032735.1 49474693 2867543 complement(1413417..1413950) 1 NC_005955.1 hypothetical protein 1413950 2867543 BQ12060 Bartonella quintana str. Toulouse hypothetical protein YP_032735.1 1413417 R 283165 CDS YP_032736.1 49474694 2866726 1414197..1414454 1 NC_005955.1 hypothetical protein 1414454 2866726 BQ12070 Bartonella quintana str. Toulouse hypothetical protein YP_032736.1 1414197 D 283165 CDS YP_032737.1 49474695 2866977 complement(1414451..1416292) 1 NC_005955.1 ABC transporter ATP-binding protein 1416292 2866977 BQ12080 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032737.1 1414451 R 283165 CDS YP_032738.1 49474696 2866996 complement(1416292..1416690) 1 NC_005955.1 hypothetical protein 1416690 2866996 BQ12090 Bartonella quintana str. Toulouse hypothetical protein YP_032738.1 1416292 R 283165 CDS YP_032739.1 49474697 2866988 complement(1416794..1417429) 1 NC_005955.1 hypothetical protein 1417429 2866988 BQ12100 Bartonella quintana str. Toulouse hypothetical protein YP_032739.1 1416794 R 283165 CDS YP_032740.1 49474698 2867389 1417661..1419106 1 NC_005955.1 hypothetical protein 1419106 2867389 BQ12110 Bartonella quintana str. Toulouse hypothetical protein YP_032740.1 1417661 D 283165 CDS YP_032741.1 49474699 2867325 complement(1419922..1420833) 1 NC_005955.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 1420833 rpoH2 2867325 rpoH2 Bartonella quintana str. Toulouse RNA polymerase factor sigma-32 YP_032741.1 1419922 R 283165 CDS YP_032742.1 49474700 2867006 1421306..1422976 1 NC_005955.1 hypothetical protein 1422976 2867006 BQ12130 Bartonella quintana str. Toulouse hypothetical protein YP_032742.1 1421306 D 283165 CDS YP_032743.1 49474701 2867037 1422997..1423335 1 NC_005955.1 ferredoxin II 1423335 fdxA 2867037 fdxA Bartonella quintana str. Toulouse ferredoxin II YP_032743.1 1422997 D 283165 CDS YP_032744.1 49474702 2867592 1423644..1424228 1 NC_005955.1 transcriptional factor regulator 1424228 2867592 BQ12150 Bartonella quintana str. Toulouse transcriptional factor regulator YP_032744.1 1423644 D 283165 CDS YP_032745.1 49474703 2866517 complement(1424776..1424955) 1 NC_005955.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1424955 rpmF 2866517 rpmF Bartonella quintana str. Toulouse 50S ribosomal protein L32 YP_032745.1 1424776 R 283165 CDS YP_032746.1 49474704 2866388 1425388..1426293 1 NC_005955.1 geranyltranstransferase (farnesyl-diphosphate synthase) 1426293 ispA 2866388 ispA Bartonella quintana str. Toulouse geranyltranstransferase (farnesyl-diphosphate synthase) YP_032746.1 1425388 D 283165 CDS YP_032747.1 49474705 2866375 complement(1426362..1427603) 1 NC_005955.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1427603 ispG 2866375 ispG Bartonella quintana str. Toulouse 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_032747.1 1426362 R 283165 CDS YP_032748.1 49474706 2867596 1427839..1428123 1 NC_005955.1 hypothetical protein 1428123 2867596 BQ12190 Bartonella quintana str. Toulouse hypothetical protein YP_032748.1 1427839 D 283165 CDS YP_032749.1 49474707 2867112 complement(1428571..1429575) 1 NC_005955.1 transport protein transmembrane 1429575 2867112 BQ12200 Bartonella quintana str. Toulouse transport protein transmembrane YP_032749.1 1428571 R 283165 CDS YP_032750.1 49474708 2867128 complement(1429572..1431233) 1 NC_005955.1 transport protein transmembrane 1431233 2867128 BQ12210 Bartonella quintana str. Toulouse transport protein transmembrane YP_032750.1 1429572 R 283165 CDS YP_032751.1 49474709 2867274 complement(1431256..1431672) 1 NC_005955.1 ATP synthase subunit epsilon 1431672 atpC 2867274 atpC Bartonella quintana str. Toulouse ATP synthase subunit epsilon YP_032751.1 1431256 R 283165 CDS YP_032752.1 49474710 2867275 complement(1431746..1433356) 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1433356 atpD 2867275 atpD Bartonella quintana str. Toulouse ATP synthase F0F1 subunit beta YP_032752.1 1431746 R 283165 CDS YP_032753.1 49474711 2867058 complement(1433376..1434287) 1 NC_005955.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1434287 atpG 2867058 atpG Bartonella quintana str. Toulouse ATP synthase F0F1 subunit gamma YP_032753.1 1433376 R 283165 CDS YP_032754.1 49474712 2867089 complement(1434308..1435843) 1 NC_005955.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1435843 atpA 2867089 atpA Bartonella quintana str. Toulouse ATP synthase F0F1 subunit alpha YP_032754.1 1434308 R 283165 CDS YP_032755.1 49474713 2867067 complement(1435843..1436427) 1 NC_005955.1 ATP synthase subunit delta 1436427 atpH 2867067 atpH Bartonella quintana str. Toulouse ATP synthase subunit delta YP_032755.1 1435843 R 283165 CDS YP_032756.1 49474714 2867050 complement(1437197..1439419) 1 NC_005955.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1439419 priA 2867050 priA Bartonella quintana str. Toulouse primosome assembly protein PriA YP_032756.1 1437197 R 283165 CDS YP_032757.1 49474715 2866479 1439880..1440533 1 NC_005955.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1440533 talC 2866479 talC Bartonella quintana str. Toulouse translaldolase YP_032757.1 1439880 D 283165 CDS YP_032758.1 49474716 2867608 complement(1440530..1441132) 1 NC_005955.1 hypothetical protein 1441132 2867608 BQ12300 Bartonella quintana str. Toulouse hypothetical protein YP_032758.1 1440530 R 283165 CDS YP_032759.1 49474717 2867619 complement(1441119..1443761) 1 NC_005955.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1443761 leuS 2867619 leuS Bartonella quintana str. Toulouse leucyl-tRNA synthetase YP_032759.1 1441119 R 283165 CDS YP_032760.1 49474718 2867109 1443947..1444636 1 NC_005955.1 hypothetical protein 1444636 2867109 BQ12320 Bartonella quintana str. Toulouse hypothetical protein YP_032760.1 1443947 D 283165 CDS YP_032761.1 49474719 2866783 1445263..1447221 1 NC_005955.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1447221 acs 2866783 acs Bartonella quintana str. Toulouse acetyl-CoA synthetase YP_032761.1 1445263 D 283165 CDS YP_032762.1 49474720 2867416 1447753..1448412 1 NC_005955.1 cell division protein ftsE 1448412 ftsE 2867416 ftsE Bartonella quintana str. Toulouse cell division protein ftsE YP_032762.1 1447753 D 283165 CDS YP_032763.1 49474721 2867570 1448405..1449358 1 NC_005955.1 hypothetical protein 1449358 2867570 BQ12350 Bartonella quintana str. Toulouse hypothetical protein YP_032763.1 1448405 D 283165 CDS YP_032764.1 49474722 2866424 1449345..1450037 1 NC_005955.1 hypothetical protein 1450037 2866424 BQ12360 Bartonella quintana str. Toulouse hypothetical protein YP_032764.1 1449345 D 283165 CDS YP_032765.1 49474723 2866423 complement(1451381..1453363) 1 NC_005955.1 ABC transporter ATP-binding protein 1453363 2866423 BQ12380 Bartonella quintana str. Toulouse ABC transporter ATP-binding protein YP_032765.1 1451381 R 283165 CDS YP_032766.1 49474724 2866432 complement(1453367..1454587) 1 NC_005955.1 hypothetical protein 1454587 2866432 BQ12390 Bartonella quintana str. Toulouse hypothetical protein YP_032766.1 1453367 R 283165 CDS YP_032767.1 49474725 2866398 complement(1454584..1456068) 1 NC_005955.1 hypothetical protein 1456068 2866398 BQ12400 Bartonella quintana str. Toulouse hypothetical protein YP_032767.1 1454584 R 283165 CDS YP_032768.1 49474726 2866895 complement(1456129..1456938) 1 NC_005955.1 exodeoxyribonuclease III 1456938 xthA2 2866895 xthA2 Bartonella quintana str. Toulouse exodeoxyribonuclease III YP_032768.1 1456129 R 283165 CDS YP_032769.1 49474727 2866732 complement(1456972..1457580) 1 NC_005955.1 Outer membrane lipoprotein carrier protein 1457580 2866732 BQ12420 Bartonella quintana str. Toulouse Outer membrane lipoprotein carrier protein YP_032769.1 1456972 R 283165 CDS YP_032770.1 49474728 2867419 complement(1457703..1460141) 1 NC_005955.1 DNA translocase FtsK 1460141 ftsK 2867419 ftsK Bartonella quintana str. Toulouse DNA translocase FtsK YP_032770.1 1457703 R 283165 CDS YP_032771.1 49474729 2867316 1460320..1461600 1 NC_005955.1 2-octaprenyl-6-methoxyphenyl hydroxylase 1461600 2867316 BQ12440 Bartonella quintana str. Toulouse 2-octaprenyl-6-methoxyphenyl hydroxylase YP_032771.1 1460320 D 283165 CDS YP_032772.1 49474730 2866573 complement(1462303..1462572) 1 NC_005955.1 trans-acting regulatory protein hvrA 1462572 hvrA 2866573 hvrA Bartonella quintana str. Toulouse trans-acting regulatory protein hvrA YP_032772.1 1462303 R 283165 CDS YP_032773.1 49474731 2867321 1462619..1463344 1 NC_005955.1 hypothetical protein 1463344 2867321 BQ12460 Bartonella quintana str. Toulouse hypothetical protein YP_032773.1 1462619 D 283165 CDS YP_032774.1 49474732 2866810 1463341..1463961 1 NC_005955.1 trwN protein 1463961 trwN 2866810 trwN Bartonella quintana str. Toulouse trwN protein YP_032774.1 1463341 D 283165 CDS YP_032775.1 49474733 2867110 1464105..1464383 1 NC_005955.1 korA protein 1464383 korA 2867110 korA Bartonella quintana str. Toulouse korA protein YP_032775.1 1464105 D 283165 CDS YP_032776.1 49474734 2867257 1464361..1464678 1 NC_005955.1 conjugal transfer protein TrwL 1464678 trwL1 2867257 trwL1 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032776.1 1464361 D 283165 CDS YP_032777.1 49474735 2867124 1464840..1465160 1 NC_005955.1 conjugal transfer protein TrwL 1465160 trwL2 2867124 trwL2 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032777.1 1464840 D 283165 CDS YP_032778.1 49474736 2867125 1465203..1465505 1 NC_005955.1 conjugal transfer protein TrwL 1465505 trwL3 2867125 trwL3 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032778.1 1465203 D 283165 CDS YP_032779.1 49474737 2867176 1465636..1465953 1 NC_005955.1 conjugal transfer protein TrwL 1465953 trwL4 2867176 trwL4 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032779.1 1465636 D 283165 CDS YP_032780.1 49474738 2867253 1466119..1466433 1 NC_005955.1 conjugal transfer protein TrwL 1466433 trwL5 2867253 trwL5 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032780.1 1466119 D 283165 CDS YP_032781.1 49474739 2867403 1466566..1466883 1 NC_005955.1 conjugal transfer protein TrwL 1466883 trwL6 2867403 trwL6 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032781.1 1466566 D 283165 CDS YP_032782.1 49474740 2867404 1467013..1467330 1 NC_005955.1 conjugal transfer protein TrwL 1467330 trwL7 2867404 trwL7 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032782.1 1467013 D 283165 CDS YP_032783.1 49474741 2867548 1467478..1467792 1 NC_005955.1 conjugal transfer protein TrwL 1467792 trwL8 2867548 trwL8 Bartonella quintana str. Toulouse conjugal transfer protein TrwL YP_032783.1 1467478 D 283165 CDS YP_032784.1 49474742 2866814 1467809..1468117 1 NC_005955.1 trwM protein 1468117 trwM 2866814 trwM Bartonella quintana str. Toulouse trwM protein YP_032784.1 1467809 D 283165 CDS YP_032785.1 49474743 2867351 1468120..1470591 1 NC_005955.1 trwK protein 1470591 trwK 2867351 trwK Bartonella quintana str. Toulouse trwK protein YP_032785.1 1468120 D 283165 CDS YP_032786.1 49474744 2867347 1470588..1471340 1 NC_005955.1 conjugal transfer protein TrwJ 1471340 trwJ1 2867347 trwJ1 Bartonella quintana str. Toulouse conjugal transfer protein TrwJ YP_032786.1 1470588 D 283165 CDS YP_032787.1 49474745 2867296 1471585..1472469 1 NC_005955.1 trwI1 protein 1472469 trwI1 2867296 trwI1 Bartonella quintana str. Toulouse trwI1 protein YP_032787.1 1471585 D 283165 CDS YP_032788.1 49474746 2866871 1472635..1472778 1 NC_005955.1 hypothetical protein 1472778 trwH1 2866871 trwH1 Bartonella quintana str. Toulouse hypothetical protein YP_032788.1 1472635 D 283165 CDS YP_032789.1 49474747 2867348 1472944..1473735 1 NC_005955.1 conjugal transfer protein TrwJ 1473735 trwJ2 2867348 trwJ2 Bartonella quintana str. Toulouse conjugal transfer protein TrwJ YP_032789.1 1472944 D 283165 CDS YP_032790.1 49474748 2866837 1473980..1474864 1 NC_005955.1 trwI2 protein 1474864 trwI2 2866837 trwI2 Bartonella quintana str. Toulouse trwI2 protein YP_032790.1 1473980 D 283165 CDS YP_032791.1 49474749 2866872 1475030..1475173 1 NC_005955.1 hypothetical protein 1475173 trwH2 2866872 trwH2 Bartonella quintana str. Toulouse hypothetical protein YP_032791.1 1475030 D 283165 CDS YP_032792.1 49474750 2866587 1475170..1475868 1 NC_005955.1 trwG protein 1475868 trwG 2866587 trwG Bartonella quintana str. Toulouse trwG protein YP_032792.1 1475170 D 283165 CDS YP_032793.1 49474751 2866586 1475882..1476682 1 NC_005955.1 trwF protein 1476682 trwF 2866586 trwF Bartonella quintana str. Toulouse trwF protein YP_032793.1 1475882 D 283165 CDS YP_032794.1 49474752 2866602 1476682..1477854 1 NC_005955.1 trwE protein 1477854 trwE 2866602 trwE Bartonella quintana str. Toulouse trwE protein YP_032794.1 1476682 D 283165 CDS YP_032795.1 49474753 2866601 1477829..1478890 1 NC_005955.1 trwD protein 1478890 trwD 2866601 trwD Bartonella quintana str. Toulouse trwD protein YP_032795.1 1477829 D 283165 CDS YP_032796.1 49474754 2867322 complement(1481142..1481921) 1 NC_005955.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1481921 sdhB 2867322 sdhB Bartonella quintana str. Toulouse succinate dehydrogenase iron-sulfur subunit YP_032796.1 1481142 R 283165 CDS YP_032797.1 49474755 2866880 complement(1481936..1483777) 1 NC_005955.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1483777 sdhA 2866880 sdhA Bartonella quintana str. Toulouse succinate dehydrogenase flavoprotein subunit YP_032797.1 1481936 R 283165 CDS YP_032798.1 49474756 2867288 complement(1483783..1484169) 1 NC_005955.1 succinate dehydrogenase hydrophobic membrane anchor protein 1484169 sdhD 2867288 sdhD Bartonella quintana str. Toulouse succinate dehydrogenase hydrophobic membrane anchor protein YP_032798.1 1483783 R 283165 CDS YP_032799.1 49474757 2867301 complement(1484188..1484589) 1 NC_005955.1 succinate dehydrogenase cytochrome b560 subunit 1484589 sdhC 2867301 sdhC Bartonella quintana str. Toulouse succinate dehydrogenase cytochrome b560 subunit YP_032799.1 1484188 R 283165 CDS YP_032800.1 49474758 2866745 complement(1485082..1485522) 1 NC_005955.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1485522 rplS 2866745 rplS Bartonella quintana str. Toulouse 50S ribosomal protein L19 YP_032800.1 1485082 R 283165 CDS YP_032801.1 49474759 2866558 complement(1485731..1486429) 1 NC_005955.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1486429 trmD 2866558 trmD Bartonella quintana str. Toulouse tRNA (guanine-N(1)-)-methyltransferase YP_032801.1 1485731 R 283165 CDS YP_032802.1 49474760 2867206 complement(1486426..1487019) 1 NC_005955.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1487019 rimM 2867206 rimM Bartonella quintana str. Toulouse 16S rRNA-processing protein RimM YP_032802.1 1486426 R 283165 CDS YP_032803.1 49474761 2866851 1487151..1487972 1 NC_005955.1 sapC-related protein 1487972 2866851 BQ12760 Bartonella quintana str. Toulouse sapC-related protein YP_032803.1 1487151 D 283165 CDS YP_032804.1 49474762 2866910 1487975..1488943 1 NC_005955.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1488943 xerC 2866910 xerC Bartonella quintana str. Toulouse site-specific tyrosine recombinase XerC YP_032804.1 1487975 D 283165 CDS YP_032805.1 49474763 2867567 complement(1488968..1489246) 1 NC_005955.1 transcriptional regulator bolA 1489246 bolA 2867567 bolA Bartonella quintana str. Toulouse transcriptional regulator bolA YP_032805.1 1488968 R 283165 CDS YP_032806.1 49474764 2867295 1489368..1489982 1 NC_005955.1 DnaJ related protein 1489982 2867295 BQ12790 Bartonella quintana str. Toulouse DnaJ related protein YP_032806.1 1489368 D 283165 CDS YP_032807.1 49474765 2867005 1490170..1491141 1 NC_005955.1 cobalamin biosynthesis protein cobS 1491141 cobS 2867005 cobS Bartonella quintana str. Toulouse cobalamin biosynthesis protein cobS YP_032807.1 1490170 D 283165 CDS YP_032808.1 49474766 2867207 1491171..1493075 1 NC_005955.1 cobalamin biosynthesis protein cobT 1493075 cobT 2867207 cobT Bartonella quintana str. Toulouse cobalamin biosynthesis protein cobT YP_032808.1 1491171 D 283165 CDS YP_032809.1 49474767 2866659 complement(1493309..1493602) 1 NC_005955.1 required for 70S ribosome assembly; 50S ribosomal protein L28 1493602 rpmB 2866659 rpmB Bartonella quintana str. Toulouse 50S ribosomal protein L28 YP_032809.1 1493309 R 283165 CDS YP_032810.1 49474768 2866691 1493888..1494673 1 NC_005955.1 SurF1 family protein (Surfeit 1) 1494673 surF1 2866691 surF1 Bartonella quintana str. Toulouse SurF1 family protein (Surfeit 1) YP_032810.1 1493888 D 283165 CDS YP_032811.1 49474769 2867074 complement(1496222..1497838) 1 NC_005955.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1497838 purH 2867074 purH Bartonella quintana str. Toulouse bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_032811.1 1496222 R 283165 CDS YP_032812.1 49474770 2866861 complement(1497995..1499704) 1 NC_005955.1 hypothetical protein 1499704 2866861 BQ12880 Bartonella quintana str. Toulouse hypothetical protein YP_032812.1 1497995 R 283165 CDS YP_032813.1 49474771 2866634 complement(1499770..1501113) 1 NC_005955.1 SUN protein (Fmu protein) 1501113 sun2 2866634 sun2 Bartonella quintana str. Toulouse SUN protein (Fmu protein) YP_032813.1 1499770 R 283165 CDS YP_032814.1 49474772 2866850 complement(1501173..1502222) 1 NC_005955.1 metalloprotease; heat shock protein HtpX 1502222 2866850 BQ12900 Bartonella quintana str. Toulouse heat shock protein HtpX YP_032814.1 1501173 R 283165 CDS YP_032815.1 49474773 2866864 1502262..1502522 1 NC_005955.1 hypothetical protein 1502522 2866864 BQ12910 Bartonella quintana str. Toulouse hypothetical protein YP_032815.1 1502262 D 283165 CDS YP_032816.1 49474774 2867090 complement(1502668..1503021) 1 NC_005955.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1503021 rpsP 2867090 rpsP Bartonella quintana str. Toulouse 30S ribosomal protein S16 YP_032816.1 1502668 R 283165 CDS YP_032817.1 49474775 2866746 complement(1503038..1503373) 1 NC_005955.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1503373 tyrA 2866746 tyrA Bartonella quintana str. Toulouse chorismate mutase YP_032817.1 1503038 R 283165 CDS YP_032818.1 49474776 2867388 complement(1503348..1504967) 1 NC_005955.1 Signal recognition particle protein 1504967 ffh 2867388 ffh Bartonella quintana str. Toulouse Signal recognition particle protein YP_032818.1 1503348 R 283165 CDS YP_032819.1 49474777 2866503 1506114..1510802 1 NC_005955.1 hypothetical protein 1510802 2866503 BQ12960 Bartonella quintana str. Toulouse hypothetical protein YP_032819.1 1506114 D 283165 CDS YP_032820.1 49474778 2866476 complement(1510820..1511878) 1 NC_005955.1 hypothetical protein 1511878 2866476 BQ12970 Bartonella quintana str. Toulouse hypothetical protein YP_032820.1 1510820 R 283165 CDS YP_032821.1 49474779 2867261 complement(1512041..1512787) 1 NC_005955.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; glutamine amidotransferase 1512787 2867261 BQ12980 Bartonella quintana str. Toulouse glutamine amidotransferase YP_032821.1 1512041 R 283165 CDS YP_032822.1 49474780 2867475 complement(1512882..1514438) 1 NC_005955.1 hypothetical protein 1514438 2867475 BQ12990 Bartonella quintana str. Toulouse hypothetical protein YP_032822.1 1512882 R 283165 CDS YP_032823.1 49474781 2867488 complement(1514446..1515615) 1 NC_005955.1 hypothetical protein 1515615 2867488 BQ13000 Bartonella quintana str. Toulouse hypothetical protein YP_032823.1 1514446 R 283165 CDS YP_032824.1 49474782 2866540 1515996..1517090 1 NC_005955.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1517090 2866540 BQ13010 Bartonella quintana str. Toulouse DNA-binding/iron metalloprotein/AP endonuclease YP_032824.1 1515996 D 283165 CDS YP_032825.1 49474783 2866504 1518644..1519072 1 NC_005955.1 hypothetical protein 1519072 2866504 BQ13020 Bartonella quintana str. Toulouse hypothetical protein YP_032825.1 1518644 D 283165 CDS YP_032826.1 49474784 2866757 1520256..1520939 1 NC_005955.1 two-component response regulator 1520939 2866757 BQ13040 Bartonella quintana str. Toulouse two-component response regulator YP_032826.1 1520256 D 283165 CDS YP_032827.1 49474785 2866736 complement(1521025..1521789) 1 NC_005955.1 hypothetical protein 1521789 2866736 BQ13050 Bartonella quintana str. Toulouse hypothetical protein YP_032827.1 1521025 R 283165 CDS YP_032828.1 49474786 2866734 complement(1522021..1524435) 1 NC_005955.1 hypothetical protein 1524435 2866734 BQ13060 Bartonella quintana str. Toulouse hypothetical protein YP_032828.1 1522021 R 283165 CDS YP_032829.1 49474787 2867203 complement(1524553..1525827) 1 NC_005955.1 diaminopimelate decarboxylase 1525827 lysA 2867203 lysA Bartonella quintana str. Toulouse diaminopimelate decarboxylase YP_032829.1 1524553 R 283165 CDS YP_032830.1 49474788 2866477 1527496..1528200 1 NC_005955.1 Thiol 3adisulfide interchange protein 1528200 2866477 BQ13100 Bartonella quintana str. Toulouse Thiol 3adisulfide interchange protein YP_032830.1 1527496 D 283165 CDS YP_032831.1 49474789 2866529 complement(1528706..1529560) 1 NC_005955.1 ribonuclease RNAse BN transmembrane protein 1529560 2866529 BQ13120 Bartonella quintana str. Toulouse ribonuclease RNAse BN transmembrane protein YP_032831.1 1528706 R 283165 CDS YP_032832.1 49474790 2866747 complement(1530206..1531138) 1 NC_005955.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1531138 tyrC 2866747 tyrC Bartonella quintana str. Toulouse cyclohexadienyl dehydrogenase YP_032832.1 1530206 R 283165 CDS YP_032833.1 49474791 2867228 1531338..1531601 1 NC_005955.1 hypothetical protein 1531601 2867228 BQ13140 Bartonella quintana str. Toulouse hypothetical protein YP_032833.1 1531338 D 283165 CDS YP_032834.1 49474792 2867135 complement(1531859..1532923) 1 NC_005955.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1532923 holA 2867135 holA Bartonella quintana str. Toulouse DNA polymerase III subunit delta YP_032834.1 1531859 R 283165 CDS YP_032835.1 49474793 2867306 complement(1536079..1536942) 1 NC_005955.1 phosphomethylpyrimidine kinase 1536942 thiD2 2867306 thiD2 Bartonella quintana str. Toulouse phosphomethylpyrimidine kinase YP_032835.1 1536079 R 283165 CDS YP_032836.1 49474794 2867231 1537074..1537880 1 NC_005955.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 1537880 plsC 2867231 plsC Bartonella quintana str. Toulouse 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_032836.1 1537074 D 283165 CDS YP_032837.1 49474795 2866373 1538524..1539621 1 NC_005955.1 penicillin-binding protein 1539621 dacA3 2866373 dacA3 Bartonella quintana str. Toulouse penicillin-binding protein YP_032837.1 1538524 D 283165 CDS YP_032838.1 49474796 2866685 complement(1540838..1541581) 1 NC_005955.1 hypothetical protein 1541581 2866685 BQ13240 Bartonella quintana str. Toulouse hypothetical protein YP_032838.1 1540838 R 283165 CDS YP_032839.1 49474797 2867588 complement(1541620..1542576) 1 NC_005955.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1542576 accA 2867588 accA Bartonella quintana str. Toulouse acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_032839.1 1541620 R 283165 CDS YP_032840.1 49474798 2866911 complement(1542655..1543602) 1 NC_005955.1 integrase /recombinase xerD 1543602 xerD 2866911 xerD Bartonella quintana str. Toulouse integrase /recombinase xerD YP_032840.1 1542655 R 283165 CDS YP_032841.1 49474799 2867082 1543864..1544496 1 NC_005955.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1544496 aroK 2867082 aroK Bartonella quintana str. Toulouse shikimate kinase YP_032841.1 1543864 D 283165 CDS YP_032842.1 49474800 2867442 1544471..1545604 1 NC_005955.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1545604 aroB 2867442 aroB Bartonella quintana str. Toulouse 3-dehydroquinate synthase YP_032842.1 1544471 D 283165 CDS YP_032843.1 49474801 2866844 1546008..1546403 1 NC_005955.1 hypothetical protein 1546403 2866844 BQ13290 Bartonella quintana str. Toulouse hypothetical protein YP_032843.1 1546008 D 283165 CDS YP_032844.1 49474802 2866591 1546423..1546815 1 NC_005955.1 hypothetical protein 1546815 2866591 BQ13300 Bartonella quintana str. Toulouse hypothetical protein YP_032844.1 1546423 D 283165 CDS YP_032845.1 49474803 2867259 complement(1546851..1547252) 1 NC_005955.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 1547252 phaG 2867259 phaG Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit G YP_032845.1 1546851 R 283165 CDS YP_032846.1 49474804 2866268 complement(1547249..1547530) 1 NC_005955.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit F 1547530 phaF 2866268 phaF Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit F YP_032846.1 1547249 R 283165 CDS YP_032847.1 49474805 2867607 complement(1547527..1548012) 1 NC_005955.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit E 1548012 phaE 2867607 phaE Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit E YP_032847.1 1547527 R 283165 CDS YP_032848.1 49474806 2867620 complement(1548009..1549631) 1 NC_005955.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 1549631 phaD 2867620 phaD Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit D YP_032848.1 1548009 R 283165 CDS YP_032849.1 49474807 2866425 complement(1549631..1549972) 1 NC_005955.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 1549972 phaC 2866425 phaC Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit C YP_032849.1 1549631 R 283165 CDS YP_032850.1 49474808 2866284 complement(1549972..1552893) 1 NC_005955.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; monovalent cation/H+ antiporter subunit A 1552893 phaA 2866284 phaA Bartonella quintana str. Toulouse monovalent cation/H+ antiporter subunit A YP_032850.1 1549972 R 283165 CDS YP_032851.1 49474809 2866855 complement(1553090..1553575) 1 NC_005955.1 transmembrane protein 1553575 2866855 BQ13370 Bartonella quintana str. Toulouse transmembrane protein YP_032851.1 1553090 R 283165 CDS YP_032852.1 49474810 2867544 1553747..1554844 1 NC_005955.1 carboxynorspermidine decarboxylase 1554844 nspC 2867544 nspC Bartonella quintana str. Toulouse carboxynorspermidine decarboxylase YP_032852.1 1553747 D 283165 CDS YP_032853.1 49474811 2866338 1554904..1556142 1 NC_005955.1 hypothetical protein 1556142 2866338 BQ13390 Bartonella quintana str. Toulouse hypothetical protein YP_032853.1 1554904 D 283165 CDS YP_032854.1 49474812 2866624 complement(1557098..1558504) 1 NC_005955.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1558504 pdhD1 2866624 pdhD1 Bartonella quintana str. Toulouse dihydrolipoamide dehydrogenase YP_032854.1 1557098 R 283165 CDS YP_032855.1 49474813 2866355 complement(1558537..1559769) 1 NC_005955.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1559769 sucB 2866355 sucB Bartonella quintana str. Toulouse dihydrolipoamide succinyltransferase YP_032855.1 1558537 R 283165 CDS YP_032856.1 49474814 2866354 complement(1559800..1562799) 1 NC_005955.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1562799 sucA 2866354 sucA Bartonella quintana str. Toulouse 2-oxoglutarate dehydrogenase E1 YP_032856.1 1559800 R 283165 CDS YP_032857.1 49474815 2866769 complement(1562959..1563861) 1 NC_005955.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1563861 sucD 2866769 sucD Bartonella quintana str. Toulouse succinyl-CoA synthetase subunit alpha YP_032857.1 1562959 R 283165 CDS YP_032858.1 49474816 2866751 complement(1563865..1565061) 1 NC_005955.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1565061 sucC 2866751 sucC Bartonella quintana str. Toulouse succinyl-CoA synthetase subunit beta YP_032858.1 1563865 R 283165 CDS YP_032859.1 49474817 2866465 complement(1565157..1566119) 1 NC_005955.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1566119 mdh 2866465 mdh Bartonella quintana str. Toulouse malate dehydrogenase YP_032859.1 1565157 R 283165 CDS YP_032860.1 49474818 2866819 complement(1566405..1567580) 1 NC_005955.1 hypothetical protein 1567580 2866819 BQ13460 Bartonella quintana str. Toulouse hypothetical protein YP_032860.1 1566405 R 283165 CDS YP_032861.1 49474819 2866829 complement(1567679..1568218) 1 NC_005955.1 Outer membrane lipoprotein 1568218 2866829 BQ13470 Bartonella quintana str. Toulouse Outer membrane lipoprotein YP_032861.1 1567679 R 283165 CDS YP_032862.1 49474820 2867604 1568449..1569300 1 NC_005955.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1569300 dapF 2867604 dapF Bartonella quintana str. Toulouse diaminopimelate epimerase YP_032862.1 1568449 D 283165 CDS YP_032863.1 49474821 2866320 1569300..1570583 1 NC_005955.1 hypothetical protein 1570583 2866320 BQ13490 Bartonella quintana str. Toulouse hypothetical protein YP_032863.1 1569300 D 283165 CDS YP_032864.1 49474822 2867424 1570598..1571821 1 NC_005955.1 cell division protein ftsY 1571821 ftsY 2867424 ftsY Bartonella quintana str. Toulouse cell division protein ftsY YP_032864.1 1570598 D 283165 CDS YP_032865.1 49474823 2866391 1571818..1572507 1 NC_005955.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1572507 ispZ 2866391 ispZ Bartonella quintana str. Toulouse intracellular septation protein A YP_032865.1 1571818 D 283165 CDS YP_032866.1 49474824 2867173 1572577..1573338 1 NC_005955.1 hydroxyacylglutathione hydrolase 1573338 gloB 2867173 gloB Bartonella quintana str. Toulouse hydroxyacylglutathione hydrolase YP_032866.1 1572577 D 283165 CDS YP_032867.1 49474825 2867012 complement(1573803..1574708) 1 NC_005955.1 chromosome partitioning protein, parb 1574708 parB 2867012 parB Bartonella quintana str. Toulouse chromosome partitioning protein, parb YP_032867.1 1573803 R 283165 CDS YP_032868.1 49474826 2867250 complement(1574757..1575554) 1 NC_005955.1 chromosome partitioning protein para 1575554 parA 2867250 parA Bartonella quintana str. Toulouse chromosome partitioning protein para YP_032868.1 1574757 R 283165 CDS YP_032869.1 49474827 2867122 complement(1575561..1576208) 1 NC_005955.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1576208 gidB 2867122 gidB Bartonella quintana str. Toulouse 16S rRNA methyltransferase GidB YP_032869.1 1575561 R 283165 CDS YP_032870.1 49474828 2867595 complement(1576208..1578076) 1 NC_005955.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1578076 gidA 2867595 gidA Bartonella quintana str. Toulouse tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_032870.1 1576208 R 283165 CDS YP_032871.1 49474829 2866902 complement(1578186..1579496) 1 NC_005955.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1579496 trmE 2866902 trmE Bartonella quintana str. Toulouse tRNA modification GTPase TrmE YP_032871.1 1578186 R 283165 CDS YP_032872.1 49474830 2867252 complement(1579529..1580794) 1 NC_005955.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1580794 rho 2867252 rho Bartonella quintana str. Toulouse transcription termination factor Rho YP_032872.1 1579529 R 283165 CDS