-- dump date   	20140619_011847
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_777640.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_777641.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_777642.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
NP_777643.1	COG0711
NP_777644.1	COG0712
NP_777645.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_777646.1	COG0224
NP_777647.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_777648.1	COG0355
NP_777649.1	COG0187
NP_777650.1	COG0592
NP_777651.1	COG0593
NP_777652.1	COG0230
NP_777653.1	COG0594; RNase P protein; protein C5
NP_777654.1	COG0759
NP_777655.1	COG0706
NP_777656.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_777657.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
NP_777658.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
NP_777659.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_777660.1	COG1509
NP_777661.1	COG0231; EF-P
NP_777662.1	acts to load the DnaB helicase onto the initiation site during DNA replication
NP_777663.1	COG0742
NP_777664.1	COG0552
NP_777665.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
NP_777666.1	COG0449; hexosephosphate aminotransferase; D-fructose-6- phosphate amidotransferase; GFAT; L-glutamine-D-fructose-6-phosphate amidotransferase; glucosamine-6-phosphate synthase
NP_777667.1	COG1207; N-acetylglucosamine-1-phosphate uridyltransferase
NP_777668.1	COG0561; YigL
NP_777669.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
NP_777670.1	COG0138; bifunctional purine biosynthesis protein PurH; AICAR transformylase; inosinicase; IMP synthetase; ATIC
NP_777671.1	COG0776; DNA-binding protein II; HB
NP_777672.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_777673.1	COG0085; transcriptase beta chain; RNA polymerase beta subunit
NP_777674.1	COG0222; L8
NP_777675.1	COG0244; L8
NP_777676.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
NP_777677.1	COG0080; L11 protein
NP_777678.1	COG0250
NP_777679.1	COG0690
NP_777680.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
NP_777681.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
NP_777682.1	catalyzes ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate
NP_777683.1	catalyzes the formation of arginine from (N-L-arginino)succinate
NP_777684.1	COG0607
NP_777685.1	COG1045; SAT
NP_777686.1	COG0568; sigma-70
NP_777687.1	COG0358
NP_777688.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_777689.1	COG0533; glycoprotease
NP_777690.1	COG0108; DHBP synthase; LuxH protein
NP_777691.1	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity
NP_777692.1	COG1968; undecaprenol kinase
NP_777693.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
NP_777694.1	Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
NP_777695.1	COG1925; histidine-containing protein
NP_777696.1	COG0272; polydeoxyribonucleotide synthase NAD+
NP_777697.1	COG0008; glutamate-tRNA ligase; GluRS
NP_777698.1	COG1677
NP_777699.1	COG1766
NP_777700.1	COG1536
NP_777701.1	COG1317
NP_777702.1	COG1157
NP_777703.1	COG2882
NP_777704.1	COG3144
NP_777705.1	COG1868
NP_777706.1	COG1886
NP_777707.1	COG1338
NP_777708.1	COG1987; flagellar biosynthetic protein MopD
NP_777709.1	COG1684; flagellar biosynthetic protein MopE
NP_777710.1	COG0267
NP_777711.1	COG0227
NP_777712.1	COG2911
NP_777713.1	COG0221; pyrophosphate phospho-hydrolase; PPase
NP_777714.1	COG0312; TldE protein
NP_777715.1	COG0313
NP_777716.1	COG0304; beta-ketoacyl-ACP synthase I; KAS I
NP_777717.1	Maintains the balance of metabolites in the pentose-phosphate pathway
NP_777718.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
NP_777719.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
NP_777720.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
NP_777721.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
NP_777722.1	COG2840
NP_777723.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
NP_777724.1	COG0141; HDH
NP_777725.1	COG0079; imidazole
NP_777726.1	catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate
NP_777727.1	COG0118
NP_777728.1	COG0106
NP_777729.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
NP_777730.1	COG0139; COG0140; histidine biosynthesis bifunctional protein HisIE; PRA-CH; PRA-PH
NP_777731.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
NP_777732.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
NP_777733.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
NP_777734.1	COG0037
NP_777735.1	COG0534; Na+ drug antiporter; multidrug-efflux transporter
NP_777736.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
NP_777737.1	COG2209; nitrogen fixation protein RnfA
NP_777738.1	COG2878
NP_777739.1	COG1726
NP_777740.1	COG1805; nitrogen fixation protein RnfD
NP_777741.1	COG2869; Nitrogen fixation protein RnfG
NP_777742.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
NP_777743.1	COG0177
NP_777744.1	COG0162; tyrosine-tRNA ligase; TyrRS
NP_777745.1	COG0316
NP_777746.1	YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function
NP_777747.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
NP_777748.1	COG0441; threonine-tRNA ligase; ThrRS
NP_777749.1	COG0290
NP_777750.1	COG0291; ribosomal protein A
NP_777751.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_777752.1	COG0016; phenylalanine-tRNA ligase alpha chain; PheRS
NP_777753.1	COG0073; COG0072; phenylalanine-tRNA ligase beta chain; PheRS
NP_777754.1	COG1862
NP_777755.1	COG0751
NP_777756.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_777757.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
NP_777758.1	COG1825
NP_777759.1	COG0586
NP_777760.1	COG0030; S-adenosylmethionine-6-N', N'-adenosyl rRNA dimethyltransferase; 16S rRNA dimethylase; high level kasugamycin resistance protein ksgA; kasugamycin dimethyltransferase
NP_777761.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
NP_777762.1	COG0262
NP_777763.1	COG0458; carbamoyl- phosphate synthase (ammonia); carbamoyl-phosphate synthetase (ammonia); carbamoyl-phosphate synthetase I; carbon-dioxide-ammonia ligase; CARB
NP_777764.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
NP_777765.1	COG0289; DHPR
NP_777766.1	COG0761
NP_777767.1	COG0597; prolipoprotein signal peptidase; signal peptidase II; SPase II
NP_777768.1	COG0060; isoleucine-tRNA ligase; IleRS
NP_777769.1	COG0268
NP_777770.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
NP_777771.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
NP_777772.1	COG0838; NADH-ubiquinone oxidoreductase chain A; Nuo1
NP_777773.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
NP_777774.1	NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms
NP_777775.1	Catalyzes the transfer of electrons from NADH to quinone
NP_777776.1	COG1894; NADH-ubiquinone oxidoreductase chain 6; Nuo6
NP_777777.1	Catalyzes the transfer of electrons from NADH to quinone
NP_777778.1	Catalyzes the transfer of electrons from NADH to quinone
NP_777779.1	Catalyzes the transfer of electrons from NADH to quinone
NP_777780.1	COG0839; NADH-ubiquinone oxidoreductase chain J; Nuo10
NP_777781.1	COG0713; NADH-ubiquinone oxidoreductase chain K; Nuo11
NP_777782.1	COG1009; NADH-ubiquinone oxidoreductase chain L; Nuo12
NP_777783.1	COG1008
NP_777784.1	COG1007; NADH dehydrogenase (ubiquinone); ubiquinone reductase; type I dehydrogenase; complex I dehydrogenase
NP_777785.1	COG0861
NP_777786.1	COG0285; FolC bifunctional protein; folylpoly-gamma-glutamate synthetase; FPGS
NP_777787.1	COG1286
NP_777788.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
NP_777789.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
NP_777790.1	COG2890; M.BusHemKP
NP_777791.1	COG2912
NP_777792.1	COG0282; Acetokinase
NP_777793.1	COG0857; COG0280; phosphotransacetylase
NP_777794.1	COG0633; ferredoxin
NP_777795.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
NP_777796.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_777797.1	COG0188
NP_777798.1	COG3416
NP_777799.1	COG0450; thioredoxin peroxidase 1; thioredoxin-dependent peroxide reductase 1; thiol-specific antioxidant protein; TSA; PRP; natural killer cell enhancing factor B; NKEF-B
NP_777800.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_777801.1	COG0576; Hsp-70 cofactor 2
NP_777802.1	COG0061; poly(P)/ATP NAD kinase
NP_777803.1	COG0278
NP_777804.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
NP_777805.1	COG0605; superoxide dismutase SodA
NP_777806.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_777807.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
NP_777808.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
NP_777809.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
NP_777810.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
NP_777811.1	COG1734
NP_777812.1	COG0101
NP_777813.1	bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli
NP_777814.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
NP_777815.1	catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate
NP_777816.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
NP_777817.1	COG0508; E2
NP_777818.1	COG1249; lipoamide reductase [NADH]; E3 component of alpha-ketoacid dehydrogenase complexes; lipoyl dehydrogenase; dihydrolipoyl dehydrogenase; diaphorase
NP_777819.1	COG0775
NP_777820.1	COG0316
NP_777821.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
NP_777822.1	COG0849
NP_777823.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_777824.1	COG0773; UDP-N-acetylmuramoyl-L-alanine synthetase
NP_777825.1	COG0707; undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
NP_777826.1	COG0772
NP_777827.1	COG0771; UDP-N- acetylmuramoyl-L-alanyl-D-glutamate synthetase; D-glutamic acid adding enzyme
NP_777828.1	COG0472; UDP-MurNAc-pentapeptide phosphotransferase
NP_777829.1	COG0770; UDP-MurNAc-pentapeptide synthetase; D-alanyl-D-alanine-adding enzyme
NP_777830.1	COG0769; UDP-N-acetylmuramyl-tripeptide synthetase; meso-diaminopimelate-adding enzyme; UDP-MurNAc-tripeptide synthetase
NP_777831.1	COG0768; penicillin-binding protein 3; PBP-3
NP_777832.1	COG3116
NP_777833.1	COG0275; methyltransferase
NP_777834.1	COG0440; AHAS; acetohydroxy-acid synthase small subunit; ALS
NP_777835.1	COG0028; AHAS; acetohydroxy-acid synthase large subunit; ALS
NP_777836.1	COG1477
NP_777837.1	COG0265; protease DO
NP_777838.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
NP_777839.1	COG0024; MAP; peptidase M
NP_777840.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_777841.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_777842.1	COG0528; UK; uridine monophosphate kinase; UMP kinase; SMBA protein
NP_777843.1	COG0233; ribosome releasing factor; RRF
NP_777844.1	COG0020; UPP synthetase; di-trans-poly-cis-decaprenylcistransferase; undecaprenyl diphosphate synthase; UDS
NP_777845.1	COG0764; (3R)-hydroxymyristoyl ACP dehydrase
NP_777846.1	COG0587
NP_777847.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_777848.1	COG1377
NP_777849.1	COG1298
NP_777850.1	COG0018; arginine-tRNA ligase; ARGRS
NP_777851.1	COG0491; glyoxalase II; Glx II
NP_777852.1	COG0328; RNase HI; ribonuclease H; RNase H
NP_777853.1	COG0847
NP_777854.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
NP_777855.1	COG0576; HSP-70 cofactor
NP_777856.1	COG2914
NP_777857.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_777858.1	COG0590
NP_777859.1	COG0736; holo-ACP synthase
NP_777860.1	COG1159; bex protein
NP_777861.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_777862.1	COG0681; SPase I; leader peptidase I
NP_777863.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
NP_777864.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
NP_777865.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
NP_777866.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
NP_777867.1	COG0741; murein hydrolase E
NP_777868.1	COG0623; NADH- dependent enoyl-ACP reductase; cold-shock induced protein 15; CSI15; vegetative protein 241; VEG241
NP_777869.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NP_777870.1	COG2095
NP_777871.1	COG0321; lipoate biosynthesis protein B
NP_777872.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
NP_777873.1	COG0284; OMP decarboxylase; OMPDCASE
NP_777874.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
NP_777875.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
NP_777876.1	COG1607; P14 protein
NP_777877.1	COG2917
NP_777879.1	COG0159
NP_777880.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
NP_777881.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
NP_777882.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_777883.1	COG1187; pseudouridylate synthase; uracil hydrolyase
NP_777884.1	SohB; periplasmic protein; member of the peptidase S49 family
NP_777885.1	COG0483; IMPase; IMP; inositol monophosphatase; lithium-sensitive myo-inositol monophosphatase A1
NP_777886.1	COG0820
NP_777887.1	COG0124; histidine-tRNA ligase; HisRS
NP_777888.1	COG0112; serine methylase; glycine hydroxymethyltransferase; SHMT
NP_777889.1	COG0132; dethiobiotin synthase; DTB synthetase; DTBS
NP_777890.1	COG0500
NP_777891.1	COG0156; AONS; 8-amino-7- ketopelargonate synthase; 7-keto-8-amino-pelargonic acid synthetase; 7-KAP synthetase; L-alanine--pimelyl CoA ligase
NP_777892.1	COG0502; biotin synthetase
NP_777893.1	COG0161; 7,8-diamino-pelargonic acid aminotransferase; DAPA aminotransferase
NP_777894.1	catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
NP_777895.1	COG1197; TRCF
NP_777896.1	COG0057; GAPDH
NP_777897.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
NP_777898.1	COG0415; DNA photolyase; photoreactivating enzyme
NP_777899.1	COG0327
NP_777900.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
NP_777901.1	COG0508; dihydrolipoamide transsuccinylase; E2; E2O
NP_777902.1	COG2885; surface antigen; PPL
NP_777903.1	COG0588; phosphoglyceromutase; PGAM; BPG-dependent PGAM
NP_777904.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_777905.1	COG0149; TIM
NP_777906.2	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
NP_777907.1	COG0283; CK; cytidine monophosphate kinase; CMP kinase; (MssA protein; P25
NP_777908.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
NP_777909.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
NP_777910.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_777911.1	COG0492; TRXR
NP_777912.1	COG0361
NP_777913.1	COG0173; aspartate-tRNA ligase; AspRS
NP_777914.1	COG1108
NP_777915.1	COG1121; ATP-binding protein
NP_777916.1	COG0739
NP_777917.1	COG0469; PK
NP_777918.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
NP_777919.1	metalloprotease
NP_777920.1	COG1253; COG0861
NP_777921.1	COG1214
NP_777922.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
NP_777923.1	COG2894; septum site-determining protein MinD
NP_777924.1	COG0850
NP_777925.1	COG2813; rRNA (guanine-N2-)-methyltransferase; 16S rRNA m2G1207 methyltransferase
NP_777926.1	COG0728
NP_777927.1	COG1815
NP_777928.1	COG1558; proximal rod protein
NP_777929.2	FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod
NP_777930.1	COG1749; distal rod protein
NP_777931.1	COG2063; basal body L-ring protein
NP_777932.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
NP_777933.1	COG1705
NP_777934.1	COG1530
NP_777935.1	COG0564; pseudouridylate synthase; uracil hydrolyase
NP_777936.1	COG0333
NP_777937.1	COG0331; MCT
NP_777938.1	COG1028; 3-ketoacyl- acyl carrier protein reductase
NP_777939.1	COG0236; ACP
NP_777940.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
NP_777941.1	COG0470
NP_777942.1	COG0084
NP_777943.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
NP_777944.1	COG0537
NP_777945.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_777946.1	COG1054
NP_777947.1	COG0525; valine-tRNA ligase; VALRS
NP_777948.1	COG0260; leucine aminopeptidase; LAP; leucyl aminopeptidase; aminopeptidase A/I
NP_777949.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.
NP_777950.1	COG0251; p14.5; UK114 antigen homolog
NP_777951.1	COG0513; dead-box protein
NP_777952.1	COG1185; polynucleotide phosphorylase; PNPase; CAP87K
NP_777953.1	COG0184; BS18
NP_777954.1	COG0130; tRNA pseudouridine 55 synthase; Psi55 synthase; pseudouridylate synthase; uracil hydrolyase; P35 protein
NP_777955.1	COG0858; P15B protein
NP_777956.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_777957.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_777958.1	COG1109; MrsA protein
NP_777959.1	COG0465
NP_777960.1	COG0293; rRNA (uridine-2'-O-)-methyltransferase; 23S rRNA m2U2552 methyltransferase; cell division protein FtsJ
NP_777961.1	COG0782; transcript cleavage factor GreA
NP_777962.1	COG0271
NP_777963.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_777964.1	COG0261
NP_777965.1	involved in the peptidyltransferase reaction during translation
NP_777966.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_777967.1	COG0103; BS10
NP_777968.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_777969.1	chorismate mutase; CM; prephenate dehydratase; PDT; COG1605; COG0077
NP_777970.1	COG0541; fifty-four homolog; P48
NP_777971.1	COG0228; BS17
NP_777972.1	COG0806; 21K
NP_777973.1	COG0336; M1G-methyltransferase; tRNA [GM37] methyltransferase
NP_777974.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_777975.1	COG0312
NP_777976.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
NP_777977.1	COG0564; pseudouridylate synthase; uracil hydrolyase
NP_777978.1	COG0013; alanine-tRNA ligase; AlaRS
NP_777979.1	COG1551; repressor RSMA
NP_777980.1	involved in the first step of glutathione biosynthesis
NP_777981.1	COG2356; endo I
NP_777982.1	COG0212
NP_777983.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
NP_777984.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_777985.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_777986.1	COG0148; 2-phosphoglycerate dehydratase; 2-phospho-D- glycerate hydro-lyase
NP_777987.1	This protein performs the mismatch recognition step during the DNA repair process
NP_777988.1	COG0526
NP_777989.1	COG0258
NP_777990.1	COG0218
NP_777991.1	COG1217; tyrosine phosphorylated protein A
NP_777992.1	COG0194; GMP kinase
NP_777993.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_777994.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_777995.1	catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding
NP_777996.1	COG1190; lysine-tRNA ligase; LYSRS
NP_777997.1	COG1186; RF-2
NP_777998.1	COG0354
NP_777999.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
NP_778000.1	COG0319
NP_778001.1	COG1253; TLYC
NP_778002.1	COG0495; leucine-tRNA ligase; LEURS
NP_778003.1	COG1466
NP_778004.1	COG0425
NP_778005.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
NP_778006.1	YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP)
NP_778007.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
NP_778008.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
NP_778009.1	COG0668
NP_778010.1	COG1330; exodeoxyribonuclease V polypeptide
NP_778011.1	COG1074; exodeoxyribonuclease V polypeptide
NP_778012.1	COG0507
NP_778013.1	COG0054; DMRL synthase; lumazine synthase; riboflavin synthase beta chain
NP_778014.1	COG0117; COG1985; riboflavin biosynthesis protein RibD; riboflavin-specific deaminase; HTP reductase
NP_778015.1	Regulates rRNA biosynthesis by transcriptional antitermination
NP_778016.1	COG0477
NP_778017.1	COG2920
NP_778018.1	COG0109; heme O synthase
NP_778019.1	COG3125
NP_778020.1	COG1845; ubiquinol oxidase chain C
NP_778021.1	COG0843; cytochrome O subunit 1; oxidase BO(3) subunit 1; cytochrome O ubiquinol oxidase subunit 1; ubiquinol oxidase chain A
NP_778022.1	COG1622; cytochrome O subunit 2; oxidase BO(3) subunit 2; cytochrome O ubiquinol oxidase subunit 2; ubiquinol oxidase chain B
NP_778023.1	COG0271
NP_778024.1	COG0740; endopeptidase Clp; caseinolytic protease; protease Ti; heat shock protein F21.5
NP_778025.1	binds and unfolds substrates as part of the ClpXP protease
NP_778026.1	COG0466
NP_778027.1	COG0760; PPIase D; rotamase D
NP_778028.1	COG1132; ATP-binding protein
NP_778029.1	COG1132; ATP-binding protein
NP_778030.1	COG2812
NP_778031.1	COG0718
NP_778032.1	molecular chaperone
NP_778033.1	COG0563; ATP-AMP transphosphorylase
NP_778034.1	COG0190; FolD bifunctional protein
NP_778035.1	COG0215; cysteine-tRNA ligase; CysRS
NP_778036.1	COG2921
NP_778037.1	member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator
NP_778038.1	COG0169
NP_778039.1	COG0009
NP_778040.1	COG0242; PDF; formylmethionine deformylase
NP_778041.1	COG0223
NP_778042.1	COG0203
NP_778043.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_778044.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
NP_778045.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_778046.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_778047.1	COG0257; ribosomal protein II; ribosomal protein B; BL38
NP_778048.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_778049.1	COG0200
NP_778050.1	COG1841
NP_778051.1	COG0098; BS5
NP_778052.1	COG0256
NP_778053.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_778054.1	COG0096; BS8
NP_778055.1	COG0199
NP_778056.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_778057.1	COG0198
NP_778058.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_778059.1	COG0186
NP_778060.1	COG0255
NP_778061.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
NP_778062.1	COG0092; BS3; BS2
NP_778063.1	COG0091
NP_778064.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP_778065.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_778066.1	COG0089
NP_778067.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_778068.1	COG0087
NP_778069.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_778070.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_778071.1	COG0480; EF-G
NP_778072.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_778073.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_778074.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_778075.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_778076.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
NP_778077.1	COG0545; PPiase; rotamase
NP_778078.1	COG0477
NP_778079.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_778080.1	COG0036; pentose-5-phosphate 3-epimerase; PPE; R5P3E
NP_778081.1	COG0337
NP_778082.1	COG0703; SK
NP_778083.1	COG0813; inosine phosphorylase; PNP
NP_778084.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
NP_778085.1	COG0480; RF-3
NP_778086.1	COG0316; COG0694
NP_778087.1	COG0596
NP_778088.1	COG0629; SSB; helix-destabilizing protein
NP_778089.1	COG0305
NP_778090.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
NP_778091.1	COG1678
NP_778092.1	COG0816
NP_778093.1	COG0119
NP_778094.1	COG0066; isopropylmalate isomerase; alpha-IPM isomerase; IPMI
NP_778095.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_778096.1	COG0473; beta-IPM dehydrogenase; IMDH; 3-IPM-DH
NP_778097.1	COG0325
NP_778098.1	COG0635
NP_778099.1	COG0220
NP_778100.1	COG1194
NP_778101.1	COG2924
NP_778102.1	COG0796
NP_778103.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
NP_778104.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_778105.1	catalyzes the formation of dUMP from dUTP
NP_778106.1	COG0359
NP_778107.1	COG0238
NP_778108.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_778109.1	COG0104; IMP-aspartate ligase; ADSS; AMPSASE
NP_778110.1	COG0330
NP_778111.1	COG0330
NP_778112.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
NP_778113.1	COG0323
NP_778114.1	COG0246
NP_778115.1	COG2213; COG1762; EIIABC-Mtl; mannitol- permease IIABC component; phosphotransferase enzyme II ABC component; EII-Mtl
NP_778116.1	COG0166; GPI; phosphoglucose isomerase; PGI; phosphohexose isomerase; PHI
NP_778117.1	3'-5' exoribonuclease specific for small oligoribonuclotides
NP_778118.1	COG0860
NP_778119.1	COG0254
NP_778120.1	heat shock protein involved in degradation of misfolded proteins
NP_778121.1	heat shock protein involved in degradation of misfolded proteins
NP_778122.1	COG0512; glutamine amido- transferase
NP_778123.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
NP_778124.1	COG1018; FNR; flavodoxin reductase; FLXR; FLDR
NP_778125.1	lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
NP_778127.1	COG0589
NP_778128.1	COG0306
NP_778129.1	COG0477
NP_778130.1	COG0253; DAP epimerase
NP_778131.1	COG1965
NP_778132.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
NP_778133.1	COG0526; TRX
NP_778134.1	COG0210
NP_778135.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
NP_778136.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
NP_778137.1	COG1104; NifS-like protein
NP_778138.1	COG0822
NP_778139.1	COG1076
NP_778140.1	COG0443; heat shock protein 70; heat shock protein; HSP70
NP_778141.1	COG0633
NP_778142.1	COG1160