-- dump date   	20140619_012131
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1005057000001	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1005057000002	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1005057000003	L-aspartate oxidase; Provisional; Region: PRK06175
1005057000004	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1005057000005	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1005057000006	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1005057000007	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1005057000008	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1005057000009	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1005057000010	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1005057000011	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1005057000012	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1005057000013	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1005057000014	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1005057000015	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1005057000016	beta subunit interaction interface [polypeptide binding]; other site
1005057000017	Walker A motif; other site
1005057000018	ATP binding site [chemical binding]; other site
1005057000019	Walker B motif; other site
1005057000020	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1005057000021	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1005057000022	core domain interface [polypeptide binding]; other site
1005057000023	delta subunit interface [polypeptide binding]; other site
1005057000024	epsilon subunit interface [polypeptide binding]; other site
1005057000025	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1005057000026	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1005057000027	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1005057000028	alpha subunit interaction interface [polypeptide binding]; other site
1005057000029	Walker A motif; other site
1005057000030	ATP binding site [chemical binding]; other site
1005057000031	Walker B motif; other site
1005057000032	inhibitor binding site; inhibition site
1005057000033	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1005057000034	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1005057000035	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1005057000036	gamma subunit interface [polypeptide binding]; other site
1005057000037	epsilon subunit interface [polypeptide binding]; other site
1005057000038	LBP interface [polypeptide binding]; other site
1005057000039	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1005057000040	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1005057000041	ATP binding site [chemical binding]; other site
1005057000042	Mg2+ binding site [ion binding]; other site
1005057000043	G-X-G motif; other site
1005057000044	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1005057000045	anchoring element; other site
1005057000046	dimer interface [polypeptide binding]; other site
1005057000047	ATP binding site [chemical binding]; other site
1005057000048	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1005057000049	active site
1005057000050	putative metal-binding site [ion binding]; other site
1005057000051	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1005057000052	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1005057000053	DNA polymerase III subunit beta; Validated; Region: PRK05643
1005057000054	putative DNA binding surface [nucleotide binding]; other site
1005057000055	dimer interface [polypeptide binding]; other site
1005057000056	beta-clamp/clamp loader binding surface; other site
1005057000057	beta-clamp/translesion DNA polymerase binding surface; other site
1005057000058	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1005057000059	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1005057000060	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057000061	Walker A motif; other site
1005057000062	ATP binding site [chemical binding]; other site
1005057000063	Walker B motif; other site
1005057000064	arginine finger; other site
1005057000065	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1005057000066	DnaA box-binding interface [nucleotide binding]; other site
1005057000067	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1005057000068	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1005057000069	membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Region: yidC_nterm; TIGR03593
1005057000070	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1005057000071	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1005057000072	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1005057000073	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1005057000074	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1005057000075	G1 box; other site
1005057000076	GTP/Mg2+ binding site [chemical binding]; other site
1005057000077	Switch I region; other site
1005057000078	G2 box; other site
1005057000079	Switch II region; other site
1005057000080	G3 box; other site
1005057000081	G4 box; other site
1005057000082	G5 box; other site
1005057000083	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1005057000084	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1005057000085	oligomerisation interface [polypeptide binding]; other site
1005057000086	mobile loop; other site
1005057000087	roof hairpin; other site
1005057000088	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1005057000089	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1005057000090	ring oligomerisation interface [polypeptide binding]; other site
1005057000091	ATP/Mg binding site [chemical binding]; other site
1005057000092	stacking interactions; other site
1005057000093	hinge regions; other site
1005057000094	translation elongation factor P; Region: efp; TIGR00038
1005057000095	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1005057000096	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1005057000097	RNA binding site [nucleotide binding]; other site
1005057000098	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1005057000099	RNA binding site [nucleotide binding]; other site
1005057000100	DNA replication protein DnaC; Validated; Region: PRK07952
1005057000101	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057000102	Walker A motif; other site
1005057000103	ATP binding site [chemical binding]; other site
1005057000104	Walker B motif; other site
1005057000105	primosomal protein DnaI; Provisional; Region: PRK02854
1005057000106	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1005057000107	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1005057000108	S-adenosylmethionine binding site [chemical binding]; other site
1005057000109	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1005057000110	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1005057000111	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1005057000112	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1005057000113	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1005057000114	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1005057000115	DNA binding residues [nucleotide binding]
1005057000116	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1005057000117	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1005057000118	glutaminase active site [active]
1005057000119	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1005057000120	dimer interface [polypeptide binding]; other site
1005057000121	active site
1005057000122	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1005057000123	dimer interface [polypeptide binding]; other site
1005057000124	active site
1005057000125	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: glmU; TIGR01173
1005057000126	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1005057000127	Substrate binding site; other site
1005057000128	Mg++ binding site; other site
1005057000129	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1005057000130	active site
1005057000131	substrate binding site [chemical binding]; other site
1005057000132	CoA binding site [chemical binding]; other site
1005057000133	putative hydrolase; Provisional; Region: PRK10976
1005057000134	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1005057000135	active site
1005057000136	motif I; other site
1005057000137	motif II; other site
1005057000138	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1005057000139	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1005057000140	THF binding site; other site
1005057000141	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1005057000142	substrate binding site [chemical binding]; other site
1005057000143	THF binding site; other site
1005057000144	zinc-binding site [ion binding]; other site
1005057000145	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1005057000146	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1005057000147	purine monophosphate binding site [chemical binding]; other site
1005057000148	dimer interface [polypeptide binding]; other site
1005057000149	putative catalytic residues [active]
1005057000150	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1005057000151	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1005057000152	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1005057000153	IHF dimer interface [polypeptide binding]; other site
1005057000154	IHF - DNA interface [nucleotide binding]; other site
1005057000155	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1005057000156	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1005057000157	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1005057000158	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1005057000159	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1005057000160	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1005057000161	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1005057000162	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1005057000163	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1005057000164	DNA binding site [nucleotide binding]
1005057000165	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1005057000166	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1005057000167	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1005057000168	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1005057000169	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1005057000170	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1005057000171	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1005057000172	RPB3 interaction site [polypeptide binding]; other site
1005057000173	RPB1 interaction site [polypeptide binding]; other site
1005057000174	RPB11 interaction site [polypeptide binding]; other site
1005057000175	RPB10 interaction site [polypeptide binding]; other site
1005057000176	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1005057000177	core dimer interface [polypeptide binding]; other site
1005057000178	peripheral dimer interface [polypeptide binding]; other site
1005057000179	L10 interface [polypeptide binding]; other site
1005057000180	L11 interface [polypeptide binding]; other site
1005057000181	putative EF-Tu interaction site [polypeptide binding]; other site
1005057000182	putative EF-G interaction site [polypeptide binding]; other site
1005057000183	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1005057000184	23S rRNA interface [nucleotide binding]; other site
1005057000185	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1005057000186	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1005057000187	mRNA/rRNA interface [nucleotide binding]; other site
1005057000188	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1005057000189	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1005057000190	23S rRNA interface [nucleotide binding]; other site
1005057000191	L7/L12 interface [polypeptide binding]; other site
1005057000192	putative thiostrepton binding site; other site
1005057000193	L25 interface [polypeptide binding]; other site
1005057000194	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1005057000195	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1005057000196	putative homodimer interface [polypeptide binding]; other site
1005057000197	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1005057000198	heterodimer interface [polypeptide binding]; other site
1005057000199	homodimer interface [polypeptide binding]; other site
1005057000200	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1005057000201	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1005057000202	FAD binding domain; Region: FAD_binding_4; pfam01565
1005057000203	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1005057000204	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1005057000205	FAD binding site [chemical binding]; other site
1005057000206	argininosuccinate synthase; Provisional; Region: PRK13820
1005057000207	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1005057000208	ANP binding site [chemical binding]; other site
1005057000209	Substrate Binding Site II [chemical binding]; other site
1005057000210	Substrate Binding Site I [chemical binding]; other site
1005057000211	argininosuccinate lyase; Provisional; Region: PRK04833
1005057000212	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1005057000213	active sites [active]
1005057000214	tetramer interface [polypeptide binding]; other site
1005057000215	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1005057000216	active site residue [active]
1005057000217	preprotein translocase subunit SecB; Validated; Region: PRK05751
1005057000218	SecA binding site; other site
1005057000219	Preprotein binding site; other site
1005057000220	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1005057000221	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1005057000222	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1005057000223	trimer interface [polypeptide binding]; other site
1005057000224	active site
1005057000225	substrate binding site [chemical binding]; other site
1005057000226	CoA binding site [chemical binding]; other site
1005057000227	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1005057000228	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1005057000229	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1005057000230	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1005057000231	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1005057000232	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1005057000233	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1005057000234	DNA binding residues [nucleotide binding]
1005057000235	DNA primase; Validated; Region: dnaG; PRK05667
1005057000236	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1005057000237	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1005057000238	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1005057000239	active site
1005057000240	metal binding site [ion binding]; metal-binding site
1005057000241	interdomain interaction site; other site
1005057000242	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1005057000243	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1005057000244	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1005057000245	UGMP family protein; Validated; Region: PRK09604
1005057000246	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1005057000247	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1005057000248	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1005057000249	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1005057000250	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1005057000251	putative ribose interaction site [chemical binding]; other site
1005057000252	putative ADP binding site [chemical binding]; other site
1005057000253	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13298
1005057000254	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1005057000255	active site
1005057000256	NTP binding site [chemical binding]; other site
1005057000257	metal binding triad [ion binding]; metal-binding site
1005057000258	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1005057000259	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1005057000260	PTS system glucose-specific transporter subunit; Provisional; Region: PRK09439
1005057000261	HPr interaction site; other site
1005057000262	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1005057000263	active site
1005057000264	phosphorylation site [posttranslational modification]
1005057000265	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1005057000266	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1005057000267	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1005057000268	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1005057000269	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1005057000270	dimerization domain swap beta strand [polypeptide binding]; other site
1005057000271	regulatory protein interface [polypeptide binding]; other site
1005057000272	active site
1005057000273	regulatory phosphorylation site [posttranslational modification]; other site
1005057000274	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1005057000275	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1005057000276	dimer interface [polypeptide binding]; other site
1005057000277	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1005057000278	catalytic residue [active]
1005057000279	NAD-dependent DNA ligase (contains BRCT domain type II) [DNA replication, recombination, and repair]; Region: Lig; COG0272
1005057000280	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1005057000281	nucleotide binding pocket [chemical binding]; other site
1005057000282	K-X-D-G motif; other site
1005057000283	catalytic site [active]
1005057000284	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1005057000285	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1005057000286	Dimer interface [polypeptide binding]; other site
1005057000287	BRCT sequence motif; other site
1005057000288	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1005057000289	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1005057000290	HIGH motif; other site
1005057000291	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1005057000292	active site
1005057000293	KMSKS motif; other site
1005057000294	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
1005057000295	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1005057000296	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1005057000297	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1005057000298	Flagellar motor switch protein [Cell motility and secretion]; Region: FliG; COG1536
1005057000299	FliG C-terminal domain; Region: FliG_C; pfam01706
1005057000300	Flagellar biosynthesis/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliH; COG1317
1005057000301	Flagellar assembly protein FliH; Region: FliH; pfam02108
1005057000302	flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496
1005057000303	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1005057000304	Walker A motif; other site
1005057000305	ATP binding site [chemical binding]; other site
1005057000306	Walker B motif; other site
1005057000307	Flagellar FliJ protein; Region: FliJ; pfam02050
1005057000308	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1005057000309	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1005057000310	Flagellar motor switch protein [Cell motility and secretion]; Region: FliM; COG1868
1005057000311	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1005057000312	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1005057000313	putative bifunctional flagellar biosynthesis protein FliO/FliP; Provisional; Region: PRK12430
1005057000314	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1005057000315	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1005057000316	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1005057000317	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
1005057000318	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1005057000319	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1005057000320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1005057000321	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1005057000322	dimer interface [polypeptide binding]; other site
1005057000323	substrate binding site [chemical binding]; other site
1005057000324	metal binding sites [ion binding]; metal-binding site
1005057000325	peptidase PmbA; Provisional; Region: PRK11040
1005057000326	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1005057000327	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1005057000328	putative SAM binding site [chemical binding]; other site
1005057000329	putative homodimer interface [polypeptide binding]; other site
1005057000330	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1005057000331	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1005057000332	dimer interface [polypeptide binding]; other site
1005057000333	active site
1005057000334	transaldolase-like protein; Provisional; Region: PTZ00411
1005057000335	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1005057000336	active site
1005057000337	dimer interface [polypeptide binding]; other site
1005057000338	catalytic residue [active]
1005057000339	transketolase; Reviewed; Region: PRK12753
1005057000340	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1005057000341	TPP-binding site [chemical binding]; other site
1005057000342	dimer interface [polypeptide binding]; other site
1005057000343	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1005057000344	PYR/PP interface [polypeptide binding]; other site
1005057000345	dimer interface [polypeptide binding]; other site
1005057000346	TPP binding site [chemical binding]; other site
1005057000347	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1005057000348	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1005057000349	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1005057000350	metal binding site [ion binding]; metal-binding site
1005057000351	dimer interface [polypeptide binding]; other site
1005057000352	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1005057000353	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1005057000354	dimer interface [polypeptide binding]; other site
1005057000355	active site
1005057000356	catalytic residue [active]
1005057000357	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1005057000358	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1005057000359	Tetramer interface [polypeptide binding]; other site
1005057000360	active site
1005057000361	FMN-binding site [chemical binding]; other site
1005057000362	hypothetical protein; Provisional; Region: PRK04946
1005057000363	Smr domain; Region: Smr; pfam01713
1005057000364	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1005057000365	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1005057000366	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1005057000367	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1005057000368	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1005057000369	NAD binding site [chemical binding]; other site
1005057000370	dimerization interface [polypeptide binding]; other site
1005057000371	product binding site; other site
1005057000372	substrate binding site [chemical binding]; other site
1005057000373	zinc binding site [ion binding]; other site
1005057000374	catalytic residues [active]
1005057000375	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1005057000376	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1005057000377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1005057000378	homodimer interface [polypeptide binding]; other site
1005057000379	catalytic residue [active]
1005057000380	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1005057000381	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1005057000382	active site
1005057000383	motif I; other site
1005057000384	motif II; other site
1005057000385	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1005057000386	putative active site pocket [active]
1005057000387	4-fold oligomerization interface [polypeptide binding]; other site
1005057000388	metal binding residues [ion binding]; metal-binding site
1005057000389	3-fold/trimer interface [polypeptide binding]; other site
1005057000390	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1005057000391	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1005057000392	putative active site [active]
1005057000393	oxyanion strand; other site
1005057000394	catalytic triad [active]
1005057000395	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1005057000396	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1005057000397	catalytic residues [active]
1005057000398	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1005057000399	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1005057000400	substrate binding site [chemical binding]; other site
1005057000401	glutamase interaction surface [polypeptide binding]; other site
1005057000402	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1005057000403	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1005057000404	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1005057000405	metal binding site [ion binding]; metal-binding site
1005057000406	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1005057000407	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1005057000408	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1005057000409	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1005057000410	trimer interface [polypeptide binding]; other site
1005057000411	active site
1005057000412	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
1005057000413	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057000414	active site
1005057000415	nucleotide binding site [chemical binding]; other site
1005057000416	HIGH motif; other site
1005057000417	KMSKS motif; other site
1005057000418	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1005057000419	tRNA binding surface [nucleotide binding]; other site
1005057000420	anticodon binding site; other site
1005057000421	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1005057000422	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1005057000423	Ligand Binding Site [chemical binding]; other site
1005057000424	TilS substrate binding domain; Region: TilS; pfam09179
1005057000425	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1005057000426	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1005057000427	Lumazine binding domain; Region: Lum_binding; pfam00677
1005057000428	Lumazine binding domain; Region: Lum_binding; pfam00677
1005057000429	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1005057000430	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1005057000431	minor groove reading motif; other site
1005057000432	helix-hairpin-helix signature motif; other site
1005057000433	active site
1005057000434	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1005057000435	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1005057000436	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1005057000437	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1005057000438	active site
1005057000439	HIGH motif; other site
1005057000440	dimer interface [polypeptide binding]; other site
1005057000441	KMSKS motif; other site
1005057000442	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1005057000443	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1005057000444	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1005057000445	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1005057000446	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1005057000447	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1005057000448	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1005057000449	active site
1005057000450	dimer interface [polypeptide binding]; other site
1005057000451	motif 1; other site
1005057000452	motif 2; other site
1005057000453	motif 3; other site
1005057000454	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1005057000455	anticodon binding site; other site
1005057000456	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1005057000457	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1005057000458	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1005057000459	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1005057000460	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1005057000461	23S rRNA binding site [nucleotide binding]; other site
1005057000462	L21 binding site [polypeptide binding]; other site
1005057000463	L13 binding site [polypeptide binding]; other site
1005057000464	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1005057000465	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1005057000466	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1005057000467	dimer interface [polypeptide binding]; other site
1005057000468	motif 1; other site
1005057000469	active site
1005057000470	motif 2; other site
1005057000471	motif 3; other site
1005057000472	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1005057000473	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1005057000474	putative tRNA-binding site [nucleotide binding]; other site
1005057000475	B3/4 domain; Region: B3_4; pfam03483
1005057000476	tRNA synthetase B5 domain; Region: B5; smart00874
1005057000477	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1005057000478	dimer interface [polypeptide binding]; other site
1005057000479	motif 1; other site
1005057000480	motif 3; other site
1005057000481	motif 2; other site
1005057000482	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1005057000483	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1005057000484	IHF dimer interface [polypeptide binding]; other site
1005057000485	IHF - DNA interface [nucleotide binding]; other site
1005057000486	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1005057000487	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1005057000488	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1005057000489	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1005057000490	DALR anticodon binding domain; Region: DALR_1; pfam05746
1005057000491	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1005057000492	motif 1; other site
1005057000493	dimer interface [polypeptide binding]; other site
1005057000494	active site
1005057000495	motif 2; other site
1005057000496	motif 3; other site
1005057000497	endonuclease IV; Provisional; Region: PRK01060
1005057000498	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1005057000499	AP (apurinic/apyrimidinic) site pocket; other site
1005057000500	DNA interaction; other site
1005057000501	Metal-binding active site; metal-binding site
1005057000502	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1005057000503	5S rRNA interface [nucleotide binding]; other site
1005057000504	CTC domain interface [polypeptide binding]; other site
1005057000505	L16 interface [polypeptide binding]; other site
1005057000506	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1005057000507	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1005057000508	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1005057000509	SurA N-terminal domain; Region: SurA_N; pfam09312
1005057000510	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1005057000511	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1005057000512	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1005057000513	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1005057000514	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1005057000515	active site
1005057000516	metal binding site [ion binding]; metal-binding site
1005057000517	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1005057000518	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1005057000519	folate binding site [chemical binding]; other site
1005057000520	NADP+ binding site [chemical binding]; other site
1005057000521	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1005057000522	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1005057000523	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1005057000524	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1005057000525	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1005057000526	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1005057000527	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1005057000528	IMP binding site; other site
1005057000529	dimer interface [polypeptide binding]; other site
1005057000530	interdomain contacts; other site
1005057000531	partial ornithine binding site; other site
1005057000532	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1005057000533	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1005057000534	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1005057000535	catalytic site [active]
1005057000536	subunit interface [polypeptide binding]; other site
1005057000537	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1005057000538	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1005057000539	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1005057000540	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1005057000541	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1005057000542	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1005057000543	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1005057000544	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057000545	active site
1005057000546	HIGH motif; other site
1005057000547	nucleotide binding site [chemical binding]; other site
1005057000548	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1005057000549	active site
1005057000550	KMSKS motif; other site
1005057000551	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1005057000552	tRNA binding surface [nucleotide binding]; other site
1005057000553	anticodon binding site; other site
1005057000554	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1005057000555	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1005057000556	chaperone protein DnaJ; Provisional; Region: PRK10767
1005057000557	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1005057000558	HSP70 interaction site [polypeptide binding]; other site
1005057000559	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1005057000560	Zn binding sites [ion binding]; other site
1005057000561	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1005057000562	dimer interface [polypeptide binding]; other site
1005057000563	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1005057000564	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1005057000565	nucleotide binding site [chemical binding]; other site
1005057000566	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
1005057000567	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1005057000568	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1005057000569	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1005057000570	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1005057000571	NADH-quinone oxidoreductase, E subunit; Region: nuoE_fam; TIGR01958
1005057000572	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1005057000573	putative dimer interface [polypeptide binding]; other site
1005057000574	[2Fe-2S] cluster binding site [ion binding]; other site
1005057000575	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1005057000576	SLBB domain; Region: SLBB; pfam10531
1005057000577	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1005057000578	NADH-quinone oxidoreductase, chain G; Region: NuoG; TIGR01973
1005057000579	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1005057000580	catalytic loop [active]
1005057000581	iron binding site [ion binding]; other site
1005057000582	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1005057000583	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1005057000584	[4Fe-4S] binding site [ion binding]; other site
1005057000585	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1005057000586	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1005057000587	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1005057000588	4Fe-4S binding domain; Region: Fer4; pfam00037
1005057000589	4Fe-4S binding domain; Region: Fer4; pfam00037
1005057000590	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1005057000591	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1005057000592	proton-translocating NADH-quinone oxidoreductase, chain L; Region: NDH_I_L; TIGR01974
1005057000593	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1005057000594	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1005057000595	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1005057000596	NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; Region: NuoN; COG1007
1005057000597	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1005057000598	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1005057000599	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1005057000600	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1005057000601	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1005057000602	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1005057000603	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1005057000604	active site
1005057000605	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1005057000606	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1005057000607	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1005057000608	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1005057000609	RF-1 domain; Region: RF-1; pfam00472
1005057000610	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1005057000611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1005057000612	S-adenosylmethionine binding site [chemical binding]; other site
1005057000613	hypothetical protein; Provisional; Region: PRK10941
1005057000614	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1005057000615	NAD synthetase; Reviewed; Region: nadE; cl17435
1005057000616	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1005057000617	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1005057000618	propionate/acetate kinase; Provisional; Region: PRK12379
1005057000619	phosphate acetyltransferase; Reviewed; Region: PRK05632
1005057000620	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
1005057000621	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
1005057000622	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1005057000623	dimer interface [polypeptide binding]; other site
1005057000624	putative radical transfer pathway; other site
1005057000625	diiron center [ion binding]; other site
1005057000626	tyrosyl radical; other site
1005057000627	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1005057000628	ATP cone domain; Region: ATP-cone; pfam03477
1005057000629	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1005057000630	active site
1005057000631	dimer interface [polypeptide binding]; other site
1005057000632	catalytic residues [active]
1005057000633	effector binding site; other site
1005057000634	R2 peptide binding site; other site
1005057000635	DNA gyrase subunit A; Validated; Region: PRK05560
1005057000636	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1005057000637	CAP-like domain; other site
1005057000638	active site
1005057000639	primary dimer interface [polypeptide binding]; other site
1005057000640	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1005057000641	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1005057000642	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1005057000643	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1005057000644	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1005057000645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3416
1005057000646	peroxidase; Provisional; Region: PRK15000
1005057000647	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1005057000648	dimer interface [polypeptide binding]; other site
1005057000649	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1005057000650	catalytic triad [active]
1005057000651	peroxidatic and resolving cysteines [active]
1005057000652	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1005057000653	ligand binding site [chemical binding]; other site
1005057000654	active site
1005057000655	UGI interface [polypeptide binding]; other site
1005057000656	catalytic site [active]
1005057000657	GrpE; Region: GrpE; pfam01025
1005057000658	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1005057000659	dimer interface [polypeptide binding]; other site
1005057000660	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1005057000661	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1005057000662	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1005057000663	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1005057000664	putative GSH binding site [chemical binding]; other site
1005057000665	catalytic residues [active]
1005057000666	ribonuclease T; Provisional; Region: PRK05168
1005057000667	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1005057000668	active site
1005057000669	catalytic site [active]
1005057000670	substrate binding site [chemical binding]; other site
1005057000671	superoxide dismutase; Provisional; Region: PRK10925
1005057000672	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1005057000673	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1005057000674	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1005057000675	putative active site [active]
1005057000676	catalytic residue [active]
1005057000677	GTP-binding protein YchF; Reviewed; Region: PRK09601
1005057000678	YchF GTPase; Region: YchF; cd01900
1005057000679	G1 box; other site
1005057000680	GTP/Mg2+ binding site [chemical binding]; other site
1005057000681	Switch I region; other site
1005057000682	G2 box; other site
1005057000683	Switch II region; other site
1005057000684	G3 box; other site
1005057000685	G4 box; other site
1005057000686	G5 box; other site
1005057000687	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1005057000688	threonine synthase; Validated; Region: PRK09225
1005057000689	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1005057000690	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1005057000691	catalytic residue [active]
1005057000692	homoserine kinase; Provisional; Region: PRK01212
1005057000693	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1005057000694	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1005057000695	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1005057000696	putative catalytic residues [active]
1005057000697	putative nucleotide binding site [chemical binding]; other site
1005057000698	putative aspartate binding site [chemical binding]; other site
1005057000699	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1005057000700	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1005057000701	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1005057000702	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1005057000703	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1005057000704	active site
1005057000705	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1005057000706	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1005057000707	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1005057000708	dimerization interface 3.5A [polypeptide binding]; other site
1005057000709	active site
1005057000710	penicillin-binding protein 1b; Provisional; Region: PRK14850
1005057000711	Transglycosylase; Region: Transgly; pfam00912
1005057000712	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1005057000713	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1005057000714	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1005057000715	SEC-C motif; Region: SEC-C; pfam02810
1005057000716	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1005057000717	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1005057000718	CoA-binding site [chemical binding]; other site
1005057000719	ATP-binding [chemical binding]; other site
1005057000720	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1005057000721	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1005057000722	active site
1005057000723	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1005057000724	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1005057000725	dimer interface [polypeptide binding]; other site
1005057000726	TPP-binding site [chemical binding]; other site
1005057000727	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1005057000728	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1005057000729	E3 interaction surface; other site
1005057000730	lipoyl attachment site [posttranslational modification]; other site
1005057000731	e3 binding domain; Region: E3_binding; pfam02817
1005057000732	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1005057000733	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1005057000734	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1005057000735	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1005057000736	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1005057000737	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1005057000738	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1005057000739	cell division protein FtsZ; Validated; Region: PRK09330
1005057000740	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1005057000741	nucleotide binding site [chemical binding]; other site
1005057000742	SulA interaction site; other site
1005057000743	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1005057000744	Cell division protein FtsA; Region: FtsA; smart00842
1005057000745	Cell division protein FtsA; Region: FtsA; pfam14450
1005057000746	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1005057000747	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1005057000748	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1005057000749	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1005057000750	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1005057000751	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1005057000752	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1005057000753	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1005057000754	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1005057000755	active site
1005057000756	homodimer interface [polypeptide binding]; other site
1005057000757	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1005057000758	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1005057000759	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1005057000760	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1005057000761	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1005057000762	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1005057000763	Mg++ binding site [ion binding]; other site
1005057000764	putative catalytic motif [active]
1005057000765	putative substrate binding site [chemical binding]; other site
1005057000766	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1005057000767	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1005057000768	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1005057000769	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1005057000770	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1005057000771	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1005057000772	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1005057000773	Cell division protein FtsL; Region: FtsL; cl11433
1005057000774	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1005057000775	MraW methylase family; Region: Methyltransf_5; cl17771
1005057000776	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1005057000777	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1005057000778	putative valine binding site [chemical binding]; other site
1005057000779	dimer interface [polypeptide binding]; other site
1005057000780	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1005057000781	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1005057000782	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1005057000783	PYR/PP interface [polypeptide binding]; other site
1005057000784	dimer interface [polypeptide binding]; other site
1005057000785	TPP binding site [chemical binding]; other site
1005057000786	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1005057000787	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1005057000788	TPP-binding site [chemical binding]; other site
1005057000789	dimer interface [polypeptide binding]; other site
1005057000790	serine endoprotease; Provisional; Region: PRK10942
1005057000791	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1005057000792	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1005057000793	protein binding site [polypeptide binding]; other site
1005057000794	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1005057000795	protein binding site [polypeptide binding]; other site
1005057000796	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1005057000797	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1005057000798	trimer interface [polypeptide binding]; other site
1005057000799	active site
1005057000800	substrate binding site [chemical binding]; other site
1005057000801	CoA binding site [chemical binding]; other site
1005057000802	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1005057000803	active site
1005057000804	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1005057000805	rRNA interaction site [nucleotide binding]; other site
1005057000806	S8 interaction site; other site
1005057000807	putative laminin-1 binding site; other site
1005057000808	elongation factor Ts; Provisional; Region: tsf; PRK09377
1005057000809	UBA/TS-N domain; Region: UBA; pfam00627
1005057000810	Elongation factor TS; Region: EF_TS; pfam00889
1005057000811	Elongation factor TS; Region: EF_TS; pfam00889
1005057000812	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1005057000813	putative nucleotide binding site [chemical binding]; other site
1005057000814	uridine monophosphate binding site [chemical binding]; other site
1005057000815	homohexameric interface [polypeptide binding]; other site
1005057000816	Ribosome recycling factor [Translation, ribosomal structure and biogenesis]; Region: Frr; COG0233
1005057000817	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1005057000818	hinge region; other site
1005057000819	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1005057000820	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1005057000821	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1005057000822	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1005057000823	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1005057000824	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1005057000825	catalytic residue [active]
1005057000826	putative FPP diphosphate  binding site; other site
1005057000827	putative FPP binding hydrophobic cleft; other site
1005057000828	dimer interface [polypeptide binding]; other site
1005057000829	putative IPP diphosphate binding site; other site
1005057000830	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1005057000831	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1005057000832	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1005057000833	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1005057000834	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1005057000835	Surface antigen; Region: Bac_surface_Ag; pfam01103
1005057000836	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1005057000837	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1005057000838	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1005057000839	putative active site [active]
1005057000840	putative PHP Thumb interface [polypeptide binding]; other site
1005057000841	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1005057000842	generic binding surface II; other site
1005057000843	generic binding surface I; other site
1005057000844	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1005057000845	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1005057000846	dimer interface [polypeptide binding]; other site
1005057000847	motif 1; other site
1005057000848	active site
1005057000849	motif 2; other site
1005057000850	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
1005057000851	putative deacylase active site [active]
1005057000852	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1005057000853	active site
1005057000854	motif 3; other site
1005057000855	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1005057000856	anticodon binding site; other site
1005057000857	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1005057000858	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1005057000859	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1005057000860	FHIPEP family; Region: FHIPEP; pfam00771
1005057000861	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1005057000862	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1005057000863	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1005057000864	active site
1005057000865	HIGH motif; other site
1005057000866	KMSK motif region; other site
1005057000867	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1005057000868	tRNA binding surface [nucleotide binding]; other site
1005057000869	anticodon binding site; other site
1005057000870	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1005057000871	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1005057000872	RNA/DNA hybrid binding site [nucleotide binding]; other site
1005057000873	active site
1005057000874	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1005057000875	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1005057000876	active site
1005057000877	catalytic site [active]
1005057000878	substrate binding site [chemical binding]; other site
1005057000879	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1005057000880	active site
1005057000881	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1005057000882	active site
1005057000883	GrpE; Region: GrpE; pfam01025
1005057000884	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1005057000885	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1005057000886	dimer interface [polypeptide binding]; other site
1005057000887	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1005057000888	SmpB-tmRNA interface; other site
1005057000889	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1005057000890	nucleoside/Zn binding site; other site
1005057000891	dimer interface [polypeptide binding]; other site
1005057000892	catalytic motif [active]
1005057000893	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1005057000894	GTPase [General function prediction only]; Region: Era; COG1159
1005057000895	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1005057000896	G1 box; other site
1005057000897	GTP/Mg2+ binding site [chemical binding]; other site
1005057000898	G2 box; other site
1005057000899	Switch I region; other site
1005057000900	G3 box; other site
1005057000901	Switch II region; other site
1005057000902	ribonuclease III; Reviewed; Region: rnc; PRK00102
1005057000903	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1005057000904	dimerization interface [polypeptide binding]; other site
1005057000905	active site
1005057000906	metal binding site [ion binding]; metal-binding site
1005057000907	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1005057000908	dsRNA binding site [nucleotide binding]; other site
1005057000909	signal peptidase I; Provisional; Region: PRK10861
1005057000910	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
1005057000911	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1005057000912	Catalytic site [active]
1005057000913	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1005057000914	GTP-binding protein LepA; Provisional; Region: PRK05433
1005057000915	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1005057000916	G1 box; other site
1005057000917	putative GEF interaction site [polypeptide binding]; other site
1005057000918	GTP/Mg2+ binding site [chemical binding]; other site
1005057000919	Switch I region; other site
1005057000920	G2 box; other site
1005057000921	G3 box; other site
1005057000922	Switch II region; other site
1005057000923	G4 box; other site
1005057000924	G5 box; other site
1005057000925	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1005057000926	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1005057000927	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1005057000928	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1005057000929	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1005057000930	Ligand Binding Site [chemical binding]; other site
1005057000931	adenylosuccinate lyase; Provisional; Region: PRK09285
1005057000932	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1005057000933	tetramer interface [polypeptide binding]; other site
1005057000934	active site
1005057000935	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1005057000936	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1005057000937	catalytic residue [active]
1005057000938	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1005057000939	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
1005057000940	homotetramer interface [polypeptide binding]; other site
1005057000941	NAD binding site [chemical binding]; other site
1005057000942	homodimer interface [polypeptide binding]; other site
1005057000943	substrate binding site [chemical binding]; other site
1005057000944	active site
1005057000945	exoribonuclease II; Provisional; Region: PRK05054
1005057000946	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1005057000947	RNB domain; Region: RNB; pfam00773
1005057000948	hypothetical protein; Provisional; Region: PRK11111
1005057000949	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1005057000950	lipoyl synthase; Provisional; Region: PRK05481
1005057000951	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1005057000952	active site
1005057000953	dimer interface [polypeptide binding]; other site
1005057000954	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1005057000955	dimerization interface [polypeptide binding]; other site
1005057000956	active site
1005057000957	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1005057000958	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1005057000959	putative active site [active]
1005057000960	catalytic site [active]
1005057000961	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1005057000962	putative active site [active]
1005057000963	catalytic site [active]
1005057000964	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1005057000965	Intracellular septation protein A; Region: IspA; cl01098
1005057000966	hypothetical protein; Provisional; Region: PRK02868
1005057000967	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1005057000968	substrate binding site [chemical binding]; other site
1005057000969	active site
1005057000970	catalytic residues [active]
1005057000971	heterodimer interface [polypeptide binding]; other site
1005057000972	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1005057000973	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1005057000974	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1005057000975	catalytic residue [active]
1005057000976	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1005057000977	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1005057000978	active site
1005057000979	ribulose/triose binding site [chemical binding]; other site
1005057000980	phosphate binding site [ion binding]; other site
1005057000981	substrate (anthranilate) binding pocket [chemical binding]; other site
1005057000982	product (indole) binding pocket [chemical binding]; other site
1005057000983	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1005057000984	active site
1005057000985	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1005057000986	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1005057000987	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1005057000988	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1005057000989	EamA-like transporter family; Region: EamA; pfam00892
1005057000990	EamA-like transporter family; Region: EamA; pfam00892
1005057000991	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1005057000992	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
1005057000993	RNA binding surface [nucleotide binding]; other site
1005057000994	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1005057000995	probable active site [active]
1005057000996	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1005057000997	putative inner membrane peptidase; Provisional; Region: PRK11778
1005057000998	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1005057000999	tandem repeat interface [polypeptide binding]; other site
1005057001000	oligomer interface [polypeptide binding]; other site
1005057001001	active site residues [active]
1005057001002	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1005057001003	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1005057001004	active site
1005057001005	interdomain interaction site; other site
1005057001006	putative metal-binding site [ion binding]; other site
1005057001007	nucleotide binding site [chemical binding]; other site
1005057001008	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1005057001009	domain I; other site
1005057001010	DNA binding groove [nucleotide binding]
1005057001011	phosphate binding site [ion binding]; other site
1005057001012	domain II; other site
1005057001013	domain III; other site
1005057001014	nucleotide binding site [chemical binding]; other site
1005057001015	catalytic site [active]
1005057001016	domain IV; other site
1005057001017	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1005057001018	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1005057001019	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1005057001020	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1005057001021	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1005057001022	active site
1005057001023	dimerization interface [polypeptide binding]; other site
1005057001024	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1005057001025	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1005057001026	FeS/SAM binding site; other site
1005057001027	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1005057001028	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1005057001029	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1005057001030	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
1005057001031	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1005057001032	dimer interface [polypeptide binding]; other site
1005057001033	motif 1; other site
1005057001034	active site
1005057001035	motif 2; other site
1005057001036	motif 3; other site
1005057001037	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1005057001038	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1005057001039	dimer interface [polypeptide binding]; other site
1005057001040	active site
1005057001041	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1005057001042	folate binding site [chemical binding]; other site
1005057001043	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1005057001044	AAA domain; Region: AAA_26; pfam13500
1005057001045	biotin synthase; Provisional; Region: PRK15108
1005057001046	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1005057001047	FeS/SAM binding site; other site
1005057001048	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1005057001049	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1005057001050	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1005057001051	inhibitor-cofactor binding pocket; inhibition site
1005057001052	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1005057001053	catalytic residue [active]
1005057001054	6-phosphogluconolactonase; Provisional; Region: PRK11028
1005057001055	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1005057001056	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1005057001057	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1005057001058	ATP binding site [chemical binding]; other site
1005057001059	putative Mg++ binding site [ion binding]; other site
1005057001060	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1005057001061	nucleotide binding region [chemical binding]; other site
1005057001062	ATP-binding site [chemical binding]; other site
1005057001063	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1005057001064	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
1005057001065	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1005057001066	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1005057001067	Walker A/P-loop; other site
1005057001068	ATP binding site [chemical binding]; other site
1005057001069	Q-loop/lid; other site
1005057001070	ABC transporter signature motif; other site
1005057001071	Walker B; other site
1005057001072	D-loop; other site
1005057001073	H-loop/switch region; other site
1005057001074	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1005057001075	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1005057001076	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1005057001077	flavodoxin FldA; Validated; Region: PRK09267
1005057001078	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1005057001079	DNA photolyase; Region: DNA_photolyase; pfam00875
1005057001080	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1005057001081	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1005057001082	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1005057001083	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1005057001084	TPP-binding site [chemical binding]; other site
1005057001085	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1005057001086	2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component); Region: sucB; TIGR01347
1005057001087	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1005057001088	E3 interaction surface; other site
1005057001089	lipoyl attachment site [posttranslational modification]; other site
1005057001090	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1005057001091	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1005057001092	catalytic core [active]
1005057001093	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1005057001094	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1005057001095	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1005057001096	active site
1005057001097	ADP/pyrophosphate binding site [chemical binding]; other site
1005057001098	dimerization interface [polypeptide binding]; other site
1005057001099	allosteric effector site; other site
1005057001100	fructose-1,6-bisphosphate binding site; other site
1005057001101	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1005057001102	amphipathic channel; other site
1005057001103	Asn-Pro-Ala signature motifs; other site
1005057001104	triosephosphate isomerase; Provisional; Region: PRK14565
1005057001105	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1005057001106	substrate binding site [chemical binding]; other site
1005057001107	dimer interface [polypeptide binding]; other site
1005057001108	catalytic triad [active]
1005057001109	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1005057001110	IHF dimer interface [polypeptide binding]; other site
1005057001111	IHF - DNA interface [nucleotide binding]; other site
1005057001112	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1005057001113	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1005057001114	RNA binding site [nucleotide binding]; other site
1005057001115	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1005057001116	RNA binding site [nucleotide binding]; other site
1005057001117	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1005057001118	RNA binding site [nucleotide binding]; other site
1005057001119	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1005057001120	RNA binding site [nucleotide binding]; other site
1005057001121	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1005057001122	RNA binding site [nucleotide binding]; other site
1005057001123	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1005057001124	RNA binding site [nucleotide binding]; other site
1005057001125	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1005057001126	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1005057001127	hinge; other site
1005057001128	active site
1005057001129	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
1005057001130	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1005057001131	catalytic residue [active]
1005057001132	seryl-tRNA synthetase; Provisional; Region: PRK05431
1005057001133	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1005057001134	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1005057001135	dimer interface [polypeptide binding]; other site
1005057001136	active site
1005057001137	motif 1; other site
1005057001138	motif 2; other site
1005057001139	motif 3; other site
1005057001140	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1005057001141	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1005057001142	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1005057001143	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1005057001144	rRNA binding site [nucleotide binding]; other site
1005057001145	predicted 30S ribosome binding site; other site
1005057001146	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1005057001147	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1005057001148	dimer interface [polypeptide binding]; other site
1005057001149	anticodon binding site; other site
1005057001150	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1005057001151	homodimer interface [polypeptide binding]; other site
1005057001152	motif 1; other site
1005057001153	active site
1005057001154	motif 2; other site
1005057001155	GAD domain; Region: GAD; pfam02938
1005057001156	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1005057001157	active site
1005057001158	motif 3; other site
1005057001159	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1005057001160	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1005057001161	ABC-ATPase subunit  interface; other site
1005057001162	dimer interface [polypeptide binding]; other site
1005057001163	putative PBP binding regions; other site
1005057001164	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1005057001165	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1005057001166	pyruvate kinase; Provisional; Region: PRK05826
1005057001167	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1005057001168	domain interfaces; other site
1005057001169	active site
1005057001170	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1005057001171	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1005057001172	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1005057001173	heat shock protein HtpX; Provisional; Region: PRK05457
1005057001174	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1005057001175	DNA-binding site [nucleotide binding]; DNA binding site
1005057001176	RNA-binding motif; other site
1005057001177	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1005057001178	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1005057001179	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1005057001180	Transporter associated domain; Region: CorC_HlyC; smart01091
1005057001181	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1005057001182	cell division inhibitor MinD; Provisional; Region: PRK10818
1005057001183	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1005057001184	Switch I; other site
1005057001185	Switch II; other site
1005057001186	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1005057001187	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1005057001188	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1005057001189	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1005057001190	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1005057001191	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1005057001192	S-adenosylmethionine binding site [chemical binding]; other site
1005057001193	outer membrane protein A; Reviewed; Region: PRK10808
1005057001194	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1005057001195	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1005057001196	ligand binding site [chemical binding]; other site
1005057001197	integral membrane protein MviN; Region: mviN; TIGR01695
1005057001198	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1005057001199	FlgN protein; Region: FlgN; cl09176
1005057001200	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
1005057001201	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1005057001202	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1005057001203	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1005057001204	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1005057001205	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgC; COG1558
1005057001206	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1005057001207	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1005057001208	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1005057001209	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK12633
1005057001210	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1005057001211	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
1005057001212	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1005057001213	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1005057001214	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1005057001215	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1005057001216	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1005057001217	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1005057001218	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1005057001219	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1005057001220	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1005057001221	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1005057001222	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1005057001223	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1005057001224	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1005057001225	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1005057001226	Flagellar hook-associated protein [Cell motility and secretion]; Region: FlgK; COG1256
1005057001227	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1005057001228	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1005057001229	homodimer interface [polypeptide binding]; other site
1005057001230	oligonucleotide binding site [chemical binding]; other site
1005057001231	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1005057001232	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1005057001233	RNA binding surface [nucleotide binding]; other site
1005057001234	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1005057001235	active site
1005057001236	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1005057001237	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1005057001238	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1005057001239	NAD(P) binding site [chemical binding]; other site
1005057001240	active site
1005057001241	acyl carrier protein; Provisional; Region: acpP; PRK00982
1005057001242	thymidylate kinase; Validated; Region: tmk; PRK00698
1005057001243	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1005057001244	TMP-binding site; other site
1005057001245	ATP-binding site [chemical binding]; other site
1005057001246	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1005057001247	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1005057001248	ATPase involved in DNA replication [DNA replication, recombination, and repair]; Region: HolB; COG0470
1005057001249	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1005057001250	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1005057001251	active site
1005057001252	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1005057001253	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1005057001254	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1005057001255	active site turn [active]
1005057001256	phosphorylation site [posttranslational modification]
1005057001257	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1005057001258	nucleotide binding site/active site [active]
1005057001259	HIT family signature motif; other site
1005057001260	catalytic residue [active]
1005057001261	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1005057001262	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1005057001263	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1005057001264	trimer interface [polypeptide binding]; other site
1005057001265	eyelet of channel; other site
1005057001266	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1005057001267	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1005057001268	putative dimer interface [polypeptide binding]; other site
1005057001269	putative anticodon binding site; other site
1005057001270	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1005057001271	homodimer interface [polypeptide binding]; other site
1005057001272	motif 1; other site
1005057001273	motif 2; other site
1005057001274	active site
1005057001275	motif 3; other site
1005057001276	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
1005057001277	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1005057001278	active site
1005057001279	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1005057001280	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1005057001281	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1005057001282	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1005057001283	ABC transporter ATPase component; Reviewed; Region: PRK11147
1005057001284	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1005057001285	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1005057001286	ABC transporter; Region: ABC_tran_2; pfam12848
1005057001287	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1005057001288	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1005057001289	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1005057001290	active site residue [active]
1005057001291	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1005057001292	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057001293	active site
1005057001294	HIGH motif; other site
1005057001295	nucleotide binding site [chemical binding]; other site
1005057001296	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1005057001297	active site
1005057001298	KMSKS motif; other site
1005057001299	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1005057001300	tRNA binding surface [nucleotide binding]; other site
1005057001301	anticodon binding site; other site
1005057001302	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1005057001303	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1005057001304	interface (dimer of trimers) [polypeptide binding]; other site
1005057001305	Substrate-binding/catalytic site; other site
1005057001306	Zn-binding sites [ion binding]; other site
1005057001307	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1005057001308	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1005057001309	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1005057001310	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1005057001311	homotrimer interaction site [polypeptide binding]; other site
1005057001312	putative active site [active]
1005057001313	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1005057001314	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1005057001315	ATP binding site [chemical binding]; other site
1005057001316	Mg++ binding site [ion binding]; other site
1005057001317	motif III; other site
1005057001318	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1005057001319	nucleotide binding region [chemical binding]; other site
1005057001320	ATP-binding site [chemical binding]; other site
1005057001321	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1005057001322	putative RNA binding site [nucleotide binding]; other site
1005057001323	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1005057001324	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1005057001325	RNase E interface [polypeptide binding]; other site
1005057001326	trimer interface [polypeptide binding]; other site
1005057001327	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1005057001328	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1005057001329	RNase E interface [polypeptide binding]; other site
1005057001330	trimer interface [polypeptide binding]; other site
1005057001331	active site
1005057001332	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1005057001333	putative nucleic acid binding region [nucleotide binding]; other site
1005057001334	G-X-X-G motif; other site
1005057001335	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1005057001336	RNA binding site [nucleotide binding]; other site
1005057001337	domain interface; other site
1005057001338	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1005057001339	16S/18S rRNA binding site [nucleotide binding]; other site
1005057001340	S13e-L30e interaction site [polypeptide binding]; other site
1005057001341	25S rRNA binding site [nucleotide binding]; other site
1005057001342	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1005057001343	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1005057001344	RNA binding site [nucleotide binding]; other site
1005057001345	active site
1005057001346	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1005057001347	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1005057001348	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1005057001349	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1005057001350	translation initiation factor IF-2; Region: IF-2; TIGR00487
1005057001351	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1005057001352	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1005057001353	G1 box; other site
1005057001354	putative GEF interaction site [polypeptide binding]; other site
1005057001355	GTP/Mg2+ binding site [chemical binding]; other site
1005057001356	Switch I region; other site
1005057001357	G2 box; other site
1005057001358	G3 box; other site
1005057001359	Switch II region; other site
1005057001360	G4 box; other site
1005057001361	G5 box; other site
1005057001362	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1005057001363	Translation-initiation factor 2; Region: IF-2; pfam11987
1005057001364	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1005057001365	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1005057001366	NusA N-terminal domain; Region: NusA_N; pfam08529
1005057001367	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1005057001368	RNA binding site [nucleotide binding]; other site
1005057001369	homodimer interface [polypeptide binding]; other site
1005057001370	NusA-like KH domain; Region: KH_5; pfam13184
1005057001371	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1005057001372	G-X-X-G motif; other site
1005057001373	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1005057001374	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1005057001375	Preprotein translocase SecG subunit; Region: SecG; cl09123
1005057001376	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1005057001377	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1005057001378	active site
1005057001379	substrate binding site [chemical binding]; other site
1005057001380	metal binding site [ion binding]; metal-binding site
1005057001381	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1005057001382	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057001383	Walker A motif; other site
1005057001384	ATP binding site [chemical binding]; other site
1005057001385	Walker B motif; other site
1005057001386	arginine finger; other site
1005057001387	Peptidase family M41; Region: Peptidase_M41; pfam01434
1005057001388	FtsJ-like methyltransferase; Region: FtsJ; cl17430
1005057001389	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1005057001390	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1005057001391	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1005057001392	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1005057001393	BolA-like protein; Region: BolA; cl00386
1005057001394	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1005057001395	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1005057001396	hinge; other site
1005057001397	active site
1005057001398	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1005057001399	Ribosomal protein L21 [Translation, ribosomal structure and biogenesis]; Region: RplU; COG0261
1005057001400	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1005057001401	Obg family GTPase CgtA; Region: Obg_CgtA; TIGR02729
1005057001402	GTP1/OBG; Region: GTP1_OBG; pfam01018
1005057001403	Obg GTPase; Region: Obg; cd01898
1005057001404	G1 box; other site
1005057001405	GTP/Mg2+ binding site [chemical binding]; other site
1005057001406	Switch I region; other site
1005057001407	G2 box; other site
1005057001408	G3 box; other site
1005057001409	Switch II region; other site
1005057001410	G4 box; other site
1005057001411	G5 box; other site
1005057001412	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1005057001413	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1005057001414	23S rRNA interface [nucleotide binding]; other site
1005057001415	L3 interface [polypeptide binding]; other site
1005057001416	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1005057001417	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1005057001418	Prephenate dehydratase; Region: PDT; pfam00800
1005057001419	signal recognition particle protein; Provisional; Region: PRK10867
1005057001420	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1005057001421	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1005057001422	P loop; other site
1005057001423	GTP binding site [chemical binding]; other site
1005057001424	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1005057001425	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1005057001426	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1005057001427	RimM N-terminal domain; Region: RimM; pfam01782
1005057001428	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1005057001429	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1005057001430	protease TldD; Provisional; Region: tldD; PRK10735
1005057001431	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1005057001432	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1005057001433	active site
1005057001434	trimer interface [polypeptide binding]; other site
1005057001435	dimer interface [polypeptide binding]; other site
1005057001436	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1005057001437	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1005057001438	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1005057001439	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1005057001440	RNA binding surface [nucleotide binding]; other site
1005057001441	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1005057001442	active site
1005057001443	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1005057001444	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1005057001445	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1005057001446	motif 1; other site
1005057001447	active site
1005057001448	motif 2; other site
1005057001449	motif 3; other site
1005057001450	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1005057001451	carbon storage regulator; Provisional; Region: PRK01712
1005057001452	glutamate--cysteine ligase; Provisional; Region: PRK02107
1005057001453	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1005057001454	DNA-specific endonuclease I; Provisional; Region: PRK15137
1005057001455	RNA methyltransferase, RsmE family; Region: TIGR00046
1005057001456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1005057001457	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1005057001458	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1005057001459	active site
1005057001460	dimer interface [polypeptide binding]; other site
1005057001461	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1005057001462	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057001463	active site
1005057001464	HIGH motif; other site
1005057001465	nucleotide binding site [chemical binding]; other site
1005057001466	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057001467	active site
1005057001468	KMSKS motif; other site
1005057001469	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1005057001470	CTP synthetase; Validated; Region: pyrG; PRK05380
1005057001471	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1005057001472	Catalytic site [active]
1005057001473	active site
1005057001474	UTP binding site [chemical binding]; other site
1005057001475	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1005057001476	active site
1005057001477	putative oxyanion hole; other site
1005057001478	catalytic triad [active]
1005057001479	enolase; Provisional; Region: eno; PRK00077
1005057001480	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1005057001481	dimer interface [polypeptide binding]; other site
1005057001482	metal binding site [ion binding]; metal-binding site
1005057001483	substrate binding pocket [chemical binding]; other site
1005057001484	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1005057001485	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1005057001486	Peptidase family M23; Region: Peptidase_M23; pfam01551
1005057001487	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1005057001488	homotrimer interaction site [polypeptide binding]; other site
1005057001489	zinc binding site [ion binding]; other site
1005057001490	CDP-binding sites; other site
1005057001491	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1005057001492	substrate binding site; other site
1005057001493	dimer interface; other site
1005057001494	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1005057001495	AAA domain; Region: AAA_33; pfam13671
1005057001496	ligand-binding site [chemical binding]; other site
1005057001497	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1005057001498	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1005057001499	CysD dimerization site [polypeptide binding]; other site
1005057001500	G1 box; other site
1005057001501	putative GEF interaction site [polypeptide binding]; other site
1005057001502	GTP/Mg2+ binding site [chemical binding]; other site
1005057001503	Switch I region; other site
1005057001504	G2 box; other site
1005057001505	G3 box; other site
1005057001506	Switch II region; other site
1005057001507	G4 box; other site
1005057001508	G5 box; other site
1005057001509	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1005057001510	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1005057001511	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1005057001512	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1005057001513	Active Sites [active]
1005057001514	siroheme synthase; Provisional; Region: cysG; PRK10637
1005057001515	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1005057001516	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1005057001517	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1005057001518	active site
1005057001519	SAM binding site [chemical binding]; other site
1005057001520	homodimer interface [polypeptide binding]; other site
1005057001521	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1005057001522	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1005057001523	Active Sites [active]
1005057001524	sulfite reductase subunit beta; Provisional; Region: PRK13504
1005057001525	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1005057001526	sulfite reductase [NADPH] flavoprotein, alpha-component; Region: cysJ; TIGR01931
1005057001527	Flavodoxin; Region: Flavodoxin_1; pfam00258
1005057001528	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1005057001529	FAD binding pocket [chemical binding]; other site
1005057001530	FAD binding motif [chemical binding]; other site
1005057001531	catalytic residues [active]
1005057001532	NAD binding pocket [chemical binding]; other site
1005057001533	phosphate binding motif [ion binding]; other site
1005057001534	beta-alpha-beta structure motif; other site
1005057001535	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1005057001536	catalytic residues [active]
1005057001537	hinge region; other site
1005057001538	alpha helical domain; other site
1005057001539	5'-3' exonuclease; Region: 53EXOc; smart00475
1005057001540	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1005057001541	active site
1005057001542	metal binding site 1 [ion binding]; metal-binding site
1005057001543	putative 5' ssDNA interaction site; other site
1005057001544	metal binding site 3; metal-binding site
1005057001545	metal binding site 2 [ion binding]; metal-binding site
1005057001546	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1005057001547	putative DNA binding site [nucleotide binding]; other site
1005057001548	putative metal binding site [ion binding]; other site
1005057001549	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1005057001550	G1 box; other site
1005057001551	GTP/Mg2+ binding site [chemical binding]; other site
1005057001552	Switch I region; other site
1005057001553	G2 box; other site
1005057001554	G3 box; other site
1005057001555	Switch II region; other site
1005057001556	G4 box; other site
1005057001557	G5 box; other site
1005057001558	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1005057001559	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1005057001560	G1 box; other site
1005057001561	putative GEF interaction site [polypeptide binding]; other site
1005057001562	GTP/Mg2+ binding site [chemical binding]; other site
1005057001563	Switch I region; other site
1005057001564	G2 box; other site
1005057001565	G3 box; other site
1005057001566	Switch II region; other site
1005057001567	G4 box; other site
1005057001568	G5 box; other site
1005057001569	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1005057001570	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1005057001571	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1005057001572	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1005057001573	catalytic site [active]
1005057001574	G-X2-G-X-G-K; other site
1005057001575	putative global regulator; Reviewed; Region: PRK09559
1005057001576	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1005057001577	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1005057001578	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1005057001579	RF-1 domain; Region: RF-1; pfam00472
1005057001580	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1005057001581	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1005057001582	dimer interface [polypeptide binding]; other site
1005057001583	putative anticodon binding site; other site
1005057001584	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1005057001585	motif 1; other site
1005057001586	active site
1005057001587	motif 2; other site
1005057001588	motif 3; other site
1005057001589	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1005057001590	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1005057001591	active site
1005057001592	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1005057001593	substrate binding site [chemical binding]; other site
1005057001594	catalytic residues [active]
1005057001595	dimer interface [polypeptide binding]; other site
1005057001596	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1005057001597	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1005057001598	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1005057001599	dimerization interface [polypeptide binding]; other site
1005057001600	active site
1005057001601	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1005057001602	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1005057001603	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1005057001604	FeS/SAM binding site; other site
1005057001605	TRAM domain; Region: TRAM; pfam01938
1005057001606	metal-binding heat shock protein; Provisional; Region: PRK00016
1005057001607	Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535
1005057001608	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1005057001609	Transporter associated domain; Region: CorC_HlyC; smart01091
1005057001610	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1005057001611	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1005057001612	HIGH motif; other site
1005057001613	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1005057001614	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057001615	active site
1005057001616	KMSKS motif; other site
1005057001617	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1005057001618	tRNA binding surface [nucleotide binding]; other site
1005057001619	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1005057001620	DNA polymerase III, delta subunit; Region: holA; TIGR01128
1005057001621	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1005057001622	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
1005057001623	active site
1005057001624	(T/H)XGH motif; other site
1005057001625	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
1005057001626	CPxP  motif; other site
1005057001627	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1005057001628	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1005057001629	putative antibiotic transporter; Provisional; Region: PRK10739
1005057001630	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
1005057001631	Phosphoglycerate kinase; Region: PGK; pfam00162
1005057001632	substrate binding site [chemical binding]; other site
1005057001633	hinge regions; other site
1005057001634	ADP binding site [chemical binding]; other site
1005057001635	catalytic site [active]
1005057001636	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1005057001637	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1005057001638	active site
1005057001639	intersubunit interface [polypeptide binding]; other site
1005057001640	zinc binding site [ion binding]; other site
1005057001641	Na+ binding site [ion binding]; other site
1005057001642	mechanosensitive channel MscS; Provisional; Region: PRK10334
1005057001643	Conserved TM helix; Region: TM_helix; pfam05552
1005057001644	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1005057001645	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1005057001646	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1005057001647	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1005057001648	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1005057001649	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1005057001650	Family description; Region: UvrD_C_2; pfam13538
1005057001651	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
1005057001652	AAA domain; Region: AAA_30; pfam13604
1005057001653	Family description; Region: UvrD_C_2; pfam13538
1005057001654	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1005057001655	MltA specific insert domain; Region: MltA; pfam03562
1005057001656	3D domain; Region: 3D; pfam06725
1005057001657	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1005057001658	homopentamer interface [polypeptide binding]; other site
1005057001659	active site
1005057001660	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1005057001661	catalytic motif [active]
1005057001662	Zn binding site [ion binding]; other site
1005057001663	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
1005057001664	RibD C-terminal domain; Region: RibD_C; cl17279
1005057001665	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1005057001666	putative RNA binding site [nucleotide binding]; other site
1005057001667	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1005057001668	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1005057001669	TPP-binding site; other site
1005057001670	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1005057001671	PYR/PP interface [polypeptide binding]; other site
1005057001672	dimer interface [polypeptide binding]; other site
1005057001673	TPP binding site [chemical binding]; other site
1005057001674	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1005057001675	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1005057001676	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1005057001677	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1005057001678	DsrC like protein; Region: DsrC; pfam04358
1005057001679	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1005057001680	UbiA prenyltransferase family; Region: UbiA; pfam01040
1005057001681	cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847
1005057001682	Subunit I/III interface [polypeptide binding]; other site
1005057001683	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1005057001684	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1005057001685	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1005057001686	D-pathway; other site
1005057001687	Putative ubiquinol binding site [chemical binding]; other site
1005057001688	Low-spin heme (heme b) binding site [chemical binding]; other site
1005057001689	Putative water exit pathway; other site
1005057001690	Binuclear center (heme o3/CuB) [ion binding]; other site
1005057001691	K-pathway; other site
1005057001692	Putative proton exit pathway; other site
1005057001693	cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433
1005057001694	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1005057001695	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1005057001696	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]; Region: Tig; COG0544
1005057001697	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1005057001698	Clp protease; Region: CLP_protease; pfam00574
1005057001699	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1005057001700	oligomer interface [polypeptide binding]; other site
1005057001701	active site residues [active]
1005057001702	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1005057001703	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1005057001704	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1005057001705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057001706	Walker A motif; other site
1005057001707	ATP binding site [chemical binding]; other site
1005057001708	Walker B motif; other site
1005057001709	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1005057001710	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1005057001711	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1005057001712	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1005057001713	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057001714	Walker A motif; other site
1005057001715	ATP binding site [chemical binding]; other site
1005057001716	Walker B motif; other site
1005057001717	arginine finger; other site
1005057001718	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1005057001719	periplasmic folding chaperone; Provisional; Region: PRK10788
1005057001720	SurA N-terminal domain; Region: SurA_N_3; cl07813
1005057001721	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1005057001722	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1005057001723	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1005057001724	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1005057001725	Walker A/P-loop; other site
1005057001726	ATP binding site [chemical binding]; other site
1005057001727	Q-loop/lid; other site
1005057001728	ABC transporter signature motif; other site
1005057001729	Walker B; other site
1005057001730	D-loop; other site
1005057001731	H-loop/switch region; other site
1005057001732	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1005057001733	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1005057001734	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1005057001735	Walker A/P-loop; other site
1005057001736	ATP binding site [chemical binding]; other site
1005057001737	Q-loop/lid; other site
1005057001738	ABC transporter signature motif; other site
1005057001739	Walker B; other site
1005057001740	D-loop; other site
1005057001741	H-loop/switch region; other site
1005057001742	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14961
1005057001743	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057001744	Walker A motif; other site
1005057001745	ATP binding site [chemical binding]; other site
1005057001746	Walker B motif; other site
1005057001747	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1005057001748	arginine finger; other site
1005057001749	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1005057001750	hypothetical protein; Validated; Region: PRK00153
1005057001751	heat shock protein 90; Provisional; Region: PRK05218
1005057001752	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1005057001753	ATP binding site [chemical binding]; other site
1005057001754	Mg2+ binding site [ion binding]; other site
1005057001755	G-X-G motif; other site
1005057001756	adenylate kinase; Reviewed; Region: adk; PRK00279
1005057001757	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1005057001758	AMP-binding site [chemical binding]; other site
1005057001759	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1005057001760	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1005057001761	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1005057001762	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1005057001763	homodimer interface [polypeptide binding]; other site
1005057001764	NADP binding site [chemical binding]; other site
1005057001765	substrate binding site [chemical binding]; other site
1005057001766	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1005057001767	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1005057001768	active site
1005057001769	HIGH motif; other site
1005057001770	nucleotide binding site [chemical binding]; other site
1005057001771	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1005057001772	KMSKS motif; other site
1005057001773	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1005057001774	tRNA binding surface [nucleotide binding]; other site
1005057001775	anticodon binding site; other site
1005057001776	hypothetical protein; Provisional; Region: PRK04998
1005057001777	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1005057001778	DNA-binding site [nucleotide binding]; DNA binding site
1005057001779	RNA-binding motif; other site
1005057001780	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1005057001781	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1005057001782	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1005057001783	shikimate binding site; other site
1005057001784	NAD(P) binding site [chemical binding]; other site
1005057001785	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1005057001786	Uncharacterized protein conserved in bacteria [Function unknown]; Region: Smg; COG2922
1005057001787	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1005057001788	active site
1005057001789	catalytic residues [active]
1005057001790	metal binding site [ion binding]; metal-binding site
1005057001791	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1005057001792	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1005057001793	putative active site [active]
1005057001794	substrate binding site [chemical binding]; other site
1005057001795	putative cosubstrate binding site; other site
1005057001796	catalytic site [active]
1005057001797	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1005057001798	substrate binding site [chemical binding]; other site
1005057001799	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1005057001800	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1005057001801	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1005057001802	alphaNTD homodimer interface [polypeptide binding]; other site
1005057001803	alphaNTD - beta interaction site [polypeptide binding]; other site
1005057001804	alphaNTD - beta' interaction site [polypeptide binding]; other site
1005057001805	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1005057001806	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1005057001807	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1005057001808	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1005057001809	RNA binding surface [nucleotide binding]; other site
1005057001810	30S ribosomal protein S11; Validated; Region: PRK05309
1005057001811	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1005057001812	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1005057001813	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1005057001814	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1005057001815	SecY translocase; Region: SecY; pfam00344
1005057001816	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1005057001817	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1005057001818	23S rRNA binding site [nucleotide binding]; other site
1005057001819	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1005057001820	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1005057001821	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1005057001822	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1005057001823	5S rRNA interface [nucleotide binding]; other site
1005057001824	23S rRNA interface [nucleotide binding]; other site
1005057001825	L5 interface [polypeptide binding]; other site
1005057001826	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1005057001827	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1005057001828	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1005057001829	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1005057001830	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1005057001831	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1005057001832	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1005057001833	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1005057001834	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1005057001835	RNA binding site [nucleotide binding]; other site
1005057001836	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1005057001837	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1005057001838	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1005057001839	putative translocon interaction site; other site
1005057001840	23S rRNA interface [nucleotide binding]; other site
1005057001841	signal recognition particle (SRP54) interaction site; other site
1005057001842	L23 interface [polypeptide binding]; other site
1005057001843	trigger factor interaction site; other site
1005057001844	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1005057001845	23S rRNA interface [nucleotide binding]; other site
1005057001846	5S rRNA interface [nucleotide binding]; other site
1005057001847	putative antibiotic binding site [chemical binding]; other site
1005057001848	L25 interface [polypeptide binding]; other site
1005057001849	L27 interface [polypeptide binding]; other site
1005057001850	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1005057001851	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1005057001852	G-X-X-G motif; other site
1005057001853	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1005057001854	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1005057001855	protein-rRNA interface [nucleotide binding]; other site
1005057001856	putative translocon binding site; other site
1005057001857	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1005057001858	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1005057001859	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1005057001860	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1005057001861	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1005057001862	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1005057001863	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1005057001864	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1005057001865	elongation factor Tu; Reviewed; Region: PRK00049
1005057001866	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1005057001867	G1 box; other site
1005057001868	GEF interaction site [polypeptide binding]; other site
1005057001869	GTP/Mg2+ binding site [chemical binding]; other site
1005057001870	Switch I region; other site
1005057001871	G2 box; other site
1005057001872	G3 box; other site
1005057001873	Switch II region; other site
1005057001874	G4 box; other site
1005057001875	G5 box; other site
1005057001876	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1005057001877	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1005057001878	Antibiotic Binding Site [chemical binding]; other site
1005057001879	elongation factor G; Reviewed; Region: PRK00007
1005057001880	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1005057001881	G1 box; other site
1005057001882	putative GEF interaction site [polypeptide binding]; other site
1005057001883	GTP/Mg2+ binding site [chemical binding]; other site
1005057001884	Switch I region; other site
1005057001885	G2 box; other site
1005057001886	G3 box; other site
1005057001887	Switch II region; other site
1005057001888	G4 box; other site
1005057001889	G5 box; other site
1005057001890	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1005057001891	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1005057001892	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1005057001893	30S ribosomal protein S7; Validated; Region: PRK05302
1005057001894	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1005057001895	S17 interaction site [polypeptide binding]; other site
1005057001896	S8 interaction site; other site
1005057001897	16S rRNA interaction site [nucleotide binding]; other site
1005057001898	streptomycin interaction site [chemical binding]; other site
1005057001899	23S rRNA interaction site [nucleotide binding]; other site
1005057001900	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1005057001901	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1005057001902	sulfur relay protein TusC; Validated; Region: PRK00211
1005057001903	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1005057001904	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1005057001905	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1005057001906	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1005057001907	putative transporter; Provisional; Region: PRK03699
1005057001908	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1005057001909	putative substrate translocation pore; other site
1005057001910	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1005057001911	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1005057001912	active site
1005057001913	HIGH motif; other site
1005057001914	dimer interface [polypeptide binding]; other site
1005057001915	KMSKS motif; other site
1005057001916	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1005057001917	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1005057001918	substrate binding site [chemical binding]; other site
1005057001919	hexamer interface [polypeptide binding]; other site
1005057001920	metal binding site [ion binding]; metal-binding site
1005057001921	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1005057001922	active site
1005057001923	dimer interface [polypeptide binding]; other site
1005057001924	metal binding site [ion binding]; metal-binding site
1005057001925	shikimate kinase; Reviewed; Region: aroK; PRK00131
1005057001926	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1005057001927	ADP binding site [chemical binding]; other site
1005057001928	magnesium binding site [ion binding]; other site
1005057001929	putative shikimate binding site; other site
1005057001930	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1005057001931	phosphopentomutase; Provisional; Region: PRK05362
1005057001932	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1005057001933	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1005057001934	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1005057001935	G1 box; other site
1005057001936	putative GEF interaction site [polypeptide binding]; other site
1005057001937	GTP/Mg2+ binding site [chemical binding]; other site
1005057001938	Switch I region; other site
1005057001939	G2 box; other site
1005057001940	G3 box; other site
1005057001941	Switch II region; other site
1005057001942	G4 box; other site
1005057001943	G5 box; other site
1005057001944	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1005057001945	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1005057001946	IscR-regulated protein YhgI; Region: YhgI_GntY; TIGR03341
1005057001947	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1005057001948	carboxylesterase BioH; Provisional; Region: PRK10349
1005057001949	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1005057001950	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1005057001951	dimer interface [polypeptide binding]; other site
1005057001952	ssDNA binding site [nucleotide binding]; other site
1005057001953	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1005057001954	replicative DNA helicase; Provisional; Region: PRK08006
1005057001955	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1005057001956	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1005057001957	Walker A motif; other site
1005057001958	ATP binding site [chemical binding]; other site
1005057001959	Walker B motif; other site
1005057001960	DNA binding loops [nucleotide binding]
1005057001961	glutathione synthetase; Provisional; Region: PRK05246
1005057001962	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1005057001963	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1005057001964	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1005057001965	HemN family oxidoreductase; Provisional; Region: PRK05660
1005057001966	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1005057001967	FeS/SAM binding site; other site
1005057001968	HemN C-terminal domain; Region: HemN_C; pfam06969
1005057001969	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
1005057001970	adenine DNA glycosylase; Provisional; Region: PRK10880
1005057001971	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1005057001972	minor groove reading motif; other site
1005057001973	helix-hairpin-helix signature motif; other site
1005057001974	substrate binding pocket [chemical binding]; other site
1005057001975	active site
1005057001976	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1005057001977	DNA binding and oxoG recognition site [nucleotide binding]
1005057001978	oxidative damage protection protein; Provisional; Region: PRK05408
1005057001979	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1005057001980	hypothetical protein; Provisional; Region: PRK05423
1005057001981	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1005057001982	active site
1005057001983	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1005057001984	trimer interface [polypeptide binding]; other site
1005057001985	active site
1005057001986	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1005057001987	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1005057001988	active site
1005057001989	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1005057001990	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1005057001991	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1005057001992	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1005057001993	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1005057001994	ribonuclease R; Region: RNase_R; TIGR02063
1005057001995	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1005057001996	RNB domain; Region: RNB; pfam00773
1005057001997	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1005057001998	RNA binding site [nucleotide binding]; other site
1005057001999	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1005057002000	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1005057002001	GDP-binding site [chemical binding]; other site
1005057002002	ACT binding site; other site
1005057002003	IMP binding site; other site
1005057002004	FtsH protease regulator HflC; Provisional; Region: PRK11029
1005057002005	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1005057002006	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1005057002007	HflK protein; Region: hflK; TIGR01933
1005057002008	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1005057002009	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1005057002010	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1005057002011	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1005057002012	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1005057002013	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1005057002014	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1005057002015	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1005057002016	active site
1005057002017	P-loop; other site
1005057002018	phosphorylation site [posttranslational modification]
1005057002019	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1005057002020	active site
1005057002021	phosphorylation site [posttranslational modification]
1005057002022	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1005057002023	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1005057002024	active site
1005057002025	dimer interface [polypeptide binding]; other site
1005057002026	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1005057002027	dimer interface [polypeptide binding]; other site
1005057002028	active site
1005057002029	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1005057002030	catalytic site [active]
1005057002031	putative active site [active]
1005057002032	putative substrate binding site [chemical binding]; other site
1005057002033	dimer interface [polypeptide binding]; other site
1005057002034	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1005057002035	active site
1005057002036	metal binding site [ion binding]; metal-binding site
1005057002037	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cl02713
1005057002038	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1005057002039	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1005057002040	active site
1005057002041	HslU subunit interaction site [polypeptide binding]; other site
1005057002042	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1005057002043	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1005057002044	Walker A motif; other site
1005057002045	ATP binding site [chemical binding]; other site
1005057002046	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1005057002047	Walker B motif; other site
1005057002048	arginine finger; other site
1005057002049	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1005057002050	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1005057002051	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1005057002052	putative dimer interface [polypeptide binding]; other site
1005057002053	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1005057002054	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1005057002055	FAD binding pocket [chemical binding]; other site
1005057002056	FAD binding motif [chemical binding]; other site
1005057002057	phosphate binding motif [ion binding]; other site
1005057002058	beta-alpha-beta structure motif; other site
1005057002059	NAD binding pocket [chemical binding]; other site
1005057002060	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1005057002061	poxB regulator PoxA; Provisional; Region: PRK09350
1005057002062	motif 1; other site
1005057002063	dimer interface [polypeptide binding]; other site
1005057002064	active site
1005057002065	motif 2; other site
1005057002066	motif 3; other site
1005057002067	Phosphopantetheine adenylyltransferase [Coenzyme metabolism]; Region: CoaD; COG0669
1005057002068	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1005057002069	active site
1005057002070	(T/H)XGH motif; other site
1005057002071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1005057002072	S-adenosylmethionine binding site [chemical binding]; other site
1005057002073	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1005057002074	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1005057002075	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1005057002076	putative substrate translocation pore; other site
1005057002077	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1005057002078	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1005057002079	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1005057002080	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1005057002081	putative iron binding site [ion binding]; other site
1005057002082	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1005057002083	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1005057002084	domain interfaces; other site
1005057002085	active site
1005057002086	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1005057002087	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1005057002088	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1005057002089	RNA binding site [nucleotide binding]; other site
1005057002090	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1005057002091	multimer interface [polypeptide binding]; other site
1005057002092	Walker A motif; other site
1005057002093	ATP binding site [chemical binding]; other site
1005057002094	Walker B motif; other site
1005057002095	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1005057002096	catalytic residues [active]
1005057002097	ATP-dependent DNA helicase Rep; Region: rep; TIGR01074
1005057002098	Part of AAA domain; Region: AAA_19; pfam13245
1005057002099	Family description; Region: UvrD_C_2; pfam13538
1005057002100	ketol-acid reductoisomerase; Validated; Region: PRK05225
1005057002101	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1005057002102	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1005057002103	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1005057002104	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1005057002105	cysteine desulfurase; Provisional; Region: PRK14012
1005057002106	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1005057002107	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1005057002108	catalytic residue [active]
1005057002109	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1005057002110	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1005057002111	trimerization site [polypeptide binding]; other site
1005057002112	active site
1005057002113	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1005057002114	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1005057002115	HSP70 interaction site [polypeptide binding]; other site
1005057002116	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1005057002117	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1005057002118	nucleotide binding site [chemical binding]; other site
1005057002119	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1005057002120	SBD interface [polypeptide binding]; other site
1005057002121	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1005057002122	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1005057002123	catalytic loop [active]
1005057002124	iron binding site [ion binding]; other site
1005057002125	GTP-binding protein Der; Reviewed; Region: PRK00093
1005057002126	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1005057002127	G1 box; other site
1005057002128	GTP/Mg2+ binding site [chemical binding]; other site
1005057002129	Switch I region; other site
1005057002130	G2 box; other site
1005057002131	Switch II region; other site
1005057002132	G3 box; other site
1005057002133	G4 box; other site
1005057002134	G5 box; other site
1005057002135	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1005057002136	G1 box; other site
1005057002137	GTP/Mg2+ binding site [chemical binding]; other site
1005057002138	Switch I region; other site
1005057002139	G2 box; other site
1005057002140	G3 box; other site
1005057002141	Switch II region; other site
1005057002142	G4 box; other site
1005057002143	G5 box; other site
1005057002144	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1005057002145	anthranilate synthase component I; Provisional; Region: PRK13564
1005057002146	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1005057002147	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1005057002148	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1005057002149	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1005057002150	glutamine binding [chemical binding]; other site
1005057002151	catalytic triad [active]
1005057002152	IncFII RepA protein family; Region: IncFII_repA; pfam02387
1005057002153	hypothetical protein; Provisional; Region: PRK05208
1005057002154	IncFII RepA protein family; Region: IncFII_repA; pfam02387
1005057002155	2-isopropylmalate synthase; Validated; Region: PRK00915
1005057002156	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1005057002157	active site
1005057002158	catalytic residues [active]
1005057002159	metal binding site [ion binding]; metal-binding site
1005057002160	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1005057002161	tartrate dehydrogenase; Region: TTC; TIGR02089
1005057002162	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1005057002163	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1005057002164	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1005057002165	substrate binding site [chemical binding]; other site
1005057002166	ligand binding site [chemical binding]; other site
1005057002167	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1005057002168	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1005057002169	hypothetical protein; Provisional; Region: PRK14812
1005057002170	substrate binding site [chemical binding]; other site