-- dump date 20111121_011345 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_001220645.1 148245184 5172823 1253..1462 1 NC_009478.1 hypothetical protein (NP_879740.1| conserved hypothetical protein [Bordetella pertussis Tohama I]; ZP_00300166.1| COG1724: Predicted periplasmic or secreted lipoprotein [Geobacter metallireducens GS-15]).; hypothetical protein 1462 5172823 pCM1_0001 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220645.1 1253 D 443906 CDS YP_001220646.1 148245185 5172820 1459..1857 1 NC_009478.1 hypothetical protein (YP_055986.1| hypothetical protein PPA1278 [Propionibacterium acnes KPA171202]; NP_696949.1| hypothetical protein BL1802 [Bifidobacterium longum NCC2705]). weak similarity to: smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.; hypothetical protein 1857 5172820 pCM1_0002 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220646.1 1459 D 443906 CDS YP_001220647.1 148245186 5172833 2059..2733 1 NC_009478.1 putative partitioning protein, ATPase (NP_052567.1| plasmid partition protein homolog ParA [Corynebacterium glutamicum]; ZP_00109013.1| COG1192: ATPases involved in chromosome partitioning [Nostoc punctiforme]). pfam00991, ParA, ParA family ATPase.; Conserved hypothetical protein; putative partitioning protein, ATPase 2733 parA 5172833 parA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative partitioning protein, ATPase YP_001220647.1 2059 D 443906 CDS YP_001220648.1 148245187 5172819 2730..3008 1 NC_009478.1 hypothetical protein, putative partitioning protein (ZP_00111179.1| hypothetical protein [Nostoc punctiforme]; NP_981997.1| partitioning protein ParB [Erwinia amylovora]).; putative partitioning protein 3008 parB 5172819 parB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative partitioning protein YP_001220648.1 2730 D 443906 CDS YP_001220649.1 148245188 5172818 3088..5289 1 NC_009478.1 putative membrane protein, putative coupling protein (NP_816955.1| conserved hypothetical protein [Enterococcus faecalis V583]; NP_114056.1| Mob protein [Streptococcus mutans]; AAL59680.1| conjugative coupling factor [Vibrio cholerae]). maybe involved in either mobilization or conjugation of the plasmid. weak similarity to: COG0433, Predicted ATPase [General function prediction only]; hypothetical protein 5289 traG 5172818 traG Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220649.1 3088 D 443906 CDS YP_001220650.1 148245189 5172841 5637..6128 1 NC_009478.1 hypothetical protein 6128 5172841 pCM1_0006 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220650.1 5637 D 443906 CDS YP_001220651.1 148245190 5172836 6173..6400 1 NC_009478.1 hypothetical protein 6400 5172836 pCM1_0007 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220651.1 6173 D 443906 CDS YP_001220652.1 148245191 5172827 complement(6465..6767) 1 NC_009478.1 hypothetical protein, putative transcriptional regulator ArsR family (NP_630544.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00271874.1| COG0640: Predicted transcriptional regulators [Ralstonia metallidurans CH34]). , smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor; hypothetical protein 6767 5172827 pCM1_0008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220652.1 6465 R 443906 CDS YP_001220653.1 148245192 5172829 7012..8259 1 NC_009478.1 conserved hypothetical protein containing an ATPase domain (NP_301610.1| conserved hypothetical protein [Mycobacterium leprae TN]; ZP_00292164.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]). , weak similarity to: COG0455, ATPases involved in chromosome partitioning, and COG1192, Soj, ATPases involved in chromosome partitioning.; hypothetical protein 8259 5172829 pCM1_0009 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220653.1 7012 D 443906 CDS YP_001220654.1 148245193 5172839 8307..8693 1 NC_009478.1 putative membrane protein (AAS20158.1| hypothetical protein [Arthrobacter aurescens]).; hypothetical protein 8693 5172839 pCM1_0010 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220654.1 8307 D 443906 CDS YP_001220655.1 148245194 5172831 8702..9418 1 NC_009478.1 Hypothetical protein; hypothetical protein 9418 5172831 pCM1_0011 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220655.1 8702 D 443906 CDS YP_001220656.1 148245195 5172821 9421..10848 1 NC_009478.1 putative membrane protein (NP_628307.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_627714.1| putative ATP-binding protein [Streptomyces coelicolor A3(2)]; CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]). , maybe involved in conjugation or mobilization.; Hypothetical protein; hypothetical protein 10848 5172821 pCM1_0012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220656.1 9421 D 443906 CDS YP_001220657.1 148245196 5172837 10845..12527 1 NC_009478.1 hypothetical membrane protein (AAS20155.1| membrane protein [Arthrobacter aurescens]; NP_825278.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 12527 5172837 pCM1_0013 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220657.1 10845 D 443906 CDS YP_001220658.1 148245197 5172842 12524..14095 1 NC_009478.1 putative ATP/GTP-binding protein (AAS20154.1| ATP/GTP-binding protein [Arthrobacter aurescens]; NP_628305.1| putative ATP/GTP-binding protein [Streptomyces coelicolor A3(2)]). may be involved in conjugation or mobilization. weak similarity to VirB4- ATPases (COG3451, VirB4, Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion]).; Conserved hypothetical protein; putative ATP/GTP-binding protein 14095 5172842 pCM1_0014 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP/GTP-binding protein YP_001220658.1 12524 D 443906 CDS YP_001220659.1 148245198 5172832 14110..15213 1 NC_009478.1 putative secreted protein (NP_824302.1| hypothetical protein SAV3126 [Streptomyces avermitilis MA- 4680]; CAD47991.1| hypothetical protein [Arthrobacter nicotinovorans]).; putative secreted protein 15213 5172832 pCM1_0015 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001220659.1 14110 D 443906 CDS YP_001220660.1 148245199 5172840 15210..15665 1 NC_009478.1 hypothetical protein may be involved in conjugation or mobilization. weak similarity to: pfam05286, FINO, Fertility inhibition protein (FINO). This family consists of several bacterial fertility inhibition (FINO) proteins. The conjugative transfer of F-like plasmids is repressed by FinO, an RNA binding protein.; hypothetical protein 15665 5172840 pCM1_0016 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220660.1 15210 D 443906 CDS YP_001220661.1 148245200 5172838 15659..16183 1 NC_009478.1 putative membrane protein may be involved in conjugation or mobilization.; Hypothetical protein; hypothetical protein 16183 5172838 pCM1_0017 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220661.1 15659 D 443906 CDS YP_001220662.1 148245201 5172844 16180..16938 1 NC_009478.1 putative secreted protein (NP_939455.1| Conserved hypothetical exported protein [Corynebacterium diphtheriae NCTC 13129]; ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]). may be involved in conjugation or mobilization.; putative secreted protein 16938 5172844 pCM1_0018 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001220662.1 16180 D 443906 CDS YP_001220663.1 148245202 5172830 complement(16921..17403) 1 NC_009478.1 hypothetical protein 17403 5172830 pCM1_0019 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220663.1 16921 R 443906 CDS YP_001220664.1 148245203 5172825 17651..19891 1 NC_009478.1 cellulase, endo-1,4-beta-glucanase (CAA44467.2| Cellulase [Clavibacter michiganensis]; AAK16222.1| cellulase CelA [Clavibacter michiganensis subsp. sepedonicus]; AAL83749.1| endo-beta-1,4-glucanase [Paenibacillus sp. KCTC8848P]). , known virulence factor, required for wilting of tomato. , , three domain structure: pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5). , smart00637, CBD_II, CBD_II domain., COG4305, Endoglucanase C-terminal domain/subunit and related proteins [Carbohydrate transport and metabolism]; High confidence in function and specificity; cellulase 19891 celA 5172825 celA Clavibacter michiganensis subsp. michiganensis NCPPB 382 cellulase YP_001220664.1 17651 D 443906 CDS YP_001220665.1 148245204 5172843 20350..20664 1 NC_009478.1 hypothetical protein 20664 5172843 pCM1_0021 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220665.1 20350 D 443906 CDS YP_001220666.1 148245205 5172835 20749..21036 1 NC_009478.1 hypothetical protein 21036 5172835 pCM1_0022 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220666.1 20749 D 443906 CDS YP_001220667.1 148245206 5172826 complement(21052..21993) 1 NC_009478.1 putative extracellular serine protease (NP_298723.1| hypothetical protein XF1434 [Xylella fastidiosa 9a5c]; NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; putative extracellular serine protease 21993 ppaJ 5172826 ppaJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220667.1 21052 R 443906 CDS YP_001220668.1 148245207 5172828 complement(22677..23243) 1 NC_009478.1 hypothetical protein (NP_695884.1| hypothetical protein BL0701 [Bifidobacterium longum NCC2705]).; hypothetical protein 23243 5172828 pCM1_0024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220668.1 22677 R 443906 CDS YP_001220669.1 148245208 5172834 complement(23240..23869) 1 NC_009478.1 putative recombinase/invertase (NP_052565.1| DNA recombinase homolog Pin [Corynebacterium glutamicum]; CAD48011.1| putative DNA recombinase [Arthrobacter nicotinovorans]). pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface. pfam02796, HTH_7, Helix-turn-helix domain of resolvase.; Hypothetical protein; DNA-invertase 23869 pin 5172834 pin Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA-invertase YP_001220669.1 23240 R 443906 CDS YP_001220670.1 148245209 5172822 complement(24442..24714) 1 NC_009478.1 conserved hypothetical protein (ZP_00287374.1| COG5271: AAA ATPase containing von Willebrand factor type A (vWA)domain [Enterococcus faecium]; ZP_00008330.1| hypothetical protein Rsph024340 [Rhodobacter sphaeroides]).; hypothetical protein 24714 5172822 pCM1_0026 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220670.1 24442 R 443906 CDS YP_001220671.1 148245210 5172817 24836..25072 1 NC_009478.1 hypothetical protein 25072 5172817 pCM1_0027 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220671.1 24836 D 443906 CDS YP_001220672.1 148245211 5172824 25373..26899 1 NC_009478.1 hypothetical protein, putative replication protein (AAR27480.1| RepA [Leifsonia xyli subsp. cynodontis]; CAB43095.1| putative Rep protein [Mycobacterium fortuitum]).; putative replication protein 26899 repA 5172824 repA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative replication protein YP_001220672.1 25373 D 443906 CDS YP_001220673.1 148271111 5172916 1..1539 1 NC_009479.1 conserved hypothetical protein (NP_817941.1| gp90 [Mycobacteriophage Corndog]; AAS20140.1| ParB [Arthrobacter aurescens])., , pfam02195, ParBc, ParB-like nuclease domain.; hypothetical protein 1539 5172916 pCM2_0001 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220673.1 1 D 443906 CDS YP_001220674.1 148271112 5172915 complement(1701..2021) 1 NC_009479.1 hypothetical protein 2021 5172915 pCM2_0002 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220674.1 1701 R 443906 CDS YP_001220675.1 148271113 5172914 2421..3329 1 NC_009479.1 putative antirestriction protein (T43094 hypothetical protein - Lactococcus lactis plasmid pMRC01; YP_068542.1| antirestriction protein [Yersinia pseudotuberculosis IP 32953]).; Conserved hypothetical protein; hypothetical protein 3329 5172914 pCM2_0003 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220675.1 2421 D 443906 CDS YP_001220676.1 148271114 5172913 3847..3966 1 NC_009479.1 hypothetical protein (NP_787847.1| hypothetical protein TWT719 [Tropheryma whipplei str. Twist]; YP_061785.1| hypothetical protein Lxx07640 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 3966 5172913 pCM2_0004 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220676.1 3847 D 443906 CDS YP_001220677.1 148271115 5172912 4362..4739 1 NC_009479.1 putative single-strand binding protein (NP_052579.1| single-strand binding protein homolog Ssb [Corynebacterium glutamicum]; NP_817551.1| gp102 [Mycobacteriophage CJW1]). pfam00436, SSB, Single-strand binding protein family.; Conserved hypothetical protein; hypothetical protein 4739 ssb 5172912 ssb Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220677.1 4362 D 443906 CDS YP_001220678.1 148271116 5172911 4742..5263 1 NC_009479.1 hypothetical protein 5263 5172911 pCM2_0006 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220678.1 4742 D 443906 CDS YP_001220679.1 148271117 5172910 5260..6033 1 NC_009479.1 conserved hypothetical protein, putative endonuclease (CAF19968.1| extracellular deoxyribonuclease [Corynebacterium glutamicum ATCC 13032]; NP_695460.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein 6033 5172910 pCM2_0007 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220679.1 5260 D 443906 CDS YP_001220680.1 148271118 5172909 6096..7049 1 NC_009479.1 hypothetical protein 7049 5172909 pCM2_0008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220680.1 6096 D 443906 CDS YP_001220681.1 148271119 5172908 7265..7753 1 NC_009479.1 conserved hypothetical protein, putative bacteriophage protein (YP_025588.1| conserved hypothetical protein [Mycobacterium ulcerans]; NP_954805.1| putative bacteriophage-related protein [Gordonia westfalica]).; hypothetical protein 7753 5172908 pCM2_0009 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220681.1 7265 D 443906 CDS YP_001220682.1 148271120 5172907 complement(7774..8208) 1 NC_009479.1 hypothetical protein 8208 5172907 pCM2_0010 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220682.1 7774 R 443906 CDS YP_001220683.1 148271121 5172906 8311..8550 1 NC_009479.1 hypothetical protein 8550 5172906 pCM2_0011 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220683.1 8311 D 443906 CDS YP_001220684.1 148271122 5172905 8547..9269 1 NC_009479.1 hypothetical protein (AAV52093.1| putative TraA conjugation protein [Nocardioides sp. JS614]; AAS20188.1| TraA-like protein [Arthrobacter aurescens]).; hypothetical protein 9269 5172905 pCM2_0012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220684.1 8547 D 443906 CDS YP_001220685.1 148271123 5172904 9307..13785 1 NC_009479.1 putative conjugal transfer protein (relexase/helicase) (AAS20144.1| TraA-like protein [Arthrobacter aurescens]; AAV52093.1| putative TraA conjugation protein [Nocardioides sp. JS614]).; Conserved hypothetical protein; putative conjugal transfer protein, Dtr system 13785 traA 5172904 traA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative conjugal transfer protein, Dtr system YP_001220685.1 9307 D 443906 CDS YP_001220686.1 148271124 5172903 complement(13844..14287) 1 NC_009479.1 conserved hypothetical protein (AAS20152.1| hypothetical protein [Arthrobacter aurescens]; NP_825682.1| hypothetical protein SAV4505 [Streptomyces avermitilis MA-4680]).; hypothetical protein 14287 5172903 pCM2_0014 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220686.1 13844 R 443906 CDS YP_001220687.1 148271125 5172902 complement(14385..16043) 1 NC_009479.1 conjugal transfer protein (AAS20153.1| TraG-family protein [Arthrobacter aurescens]; NP_825686.1| putative traG-family protein [Streptomyces avermitilis MA-4680])., pfam02534, TRAG, TraG/TraD family. The TraG/TraD family are bacterial conjugation proteins. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome although the exact mechanism of action is unknown. These proteins contain a P-loop and walker-B site for nucleotide binding.; Conserved hypothetical protein; conjugal transfer protein 16043 traG 5172902 traG Clavibacter michiganensis subsp. michiganensis NCPPB 382 conjugal transfer protein YP_001220687.1 14385 R 443906 CDS YP_001220688.1 148271126 5172899 complement(16650..17699) 1 NC_009479.1 conserved hypothetical protein, putative peptidoglycan lytic enzyme (NP_630954.1| putative secreted protein [Streptomyces coelicolor A3(2)]; YP_062952.1| peptidoglycan lytic protein P45 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.; hypothetical protein 17699 5172899 pCM2_0016 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220688.1 16650 R 443906 CDS YP_001220689.1 148271128 5172898 complement(17696..18181) 1 NC_009479.1 hypothetical protein (AAS20160.1| hypothetical protein [Arthrobacter aurescens]).; hypothetical protein 18181 5172898 pCM2_0017 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220689.1 17696 R 443906 CDS YP_001220690.1 148271127 5172897 17759..19210 1 NC_009479.1 conserved hypothetical protein, putative ATPase (NP_215044.1| hypothetical protein Rv0530 [Mycobacterium tuberculosis H37Rv]; YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]).; putative ATPase 19210 5172897 pCM2_0018 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001220690.1 17759 D 443906 CDS YP_001220691.1 148271129 5172896 complement(18191..19441) 1 NC_009479.1 conserved hypothetical protein, putative ATPase (YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]; NP_215044.1| hypothetical protein Rv0530 [Mycobacterium tuberculosis H37Rv]).; putative ATPase 19441 5172896 pCM2_0021 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001220691.1 18191 R 443906 CDS YP_001220692.1 148271130 5172895 complement(19451..20956) 1 NC_009479.1 conserved hypothetical protein, putative ATP- binding protein (CAD47983.1| putative ATP-binding protein [Arthrobacter nicotinovorans]; ZP_00206739.1| COG0466: ATP-dependent Lon protease, bacterial type [Bifidobacterium longum DJO10A]). weak similarity to COG3451, VirB4, Type IV secretory pathway, VirB4 components [Intracellular trafficking and secretion].; putative ATP-binding protein 20956 5172895 pCM2_0022 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-binding protein YP_001220692.1 19451 R 443906 CDS YP_001220693.1 148271131 5172894 complement(20956..22485) 1 NC_009479.1 conserved membrane protein (CAD47984.1| putative integral membrane protein [Arthrobacter nicotinovorans]; NP_696643.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein 22485 5172894 pCM2_0023 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220693.1 20956 R 443906 CDS YP_001220694.1 148271132 5172893 complement(22478..23770) 1 NC_009479.1 putative conjugal transfer protein (NP_954833.1| hypothetical protein [Gordonia westfalica]; CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]).; Conserved hypothetical protein; hypothetical protein 23770 5172893 pCM2_0024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220694.1 22478 R 443906 CDS YP_001220695.1 148271133 5172892 complement(23767..24552) 1 NC_009479.1 putative secreted protein (CAD47986.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_122034.1| hypothetical protein pnf11450 [Nocardia farcinica IFM 10152]).; Conserved hypothetical protein; putative secreted protein 24552 5172892 pCM2_0025 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001220695.1 23767 R 443906 CDS YP_001220696.1 148271134 5172891 complement(24549..24899) 1 NC_009479.1 hypothetical membrane protein (CAD47987.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein 24899 5172891 pCM2_0026 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220696.1 24549 R 443906 CDS YP_001220697.1 148271135 5172890 complement(24899..25567) 1 NC_009479.1 hypothetical protein 25567 5172890 pCM2_0027 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220697.1 24899 R 443906 CDS YP_001220698.1 148271136 5172889 complement(25686..26822) 1 NC_009479.1 conserved secreted protein, putative hydrolase (AAS20163.1| hypothetical protein [Arthrobacter aurescens]; YP_062243.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]). , , pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. InterPro: Esterase/lipase/thioesterase.; Function unclear; hypothetical protein 26822 5172889 pCM2_0028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220698.1 25686 R 443906 CDS YP_001220699.1 148271137 5172888 complement(26819..27736) 1 NC_009479.1 hypothetical membrane protein (CAD47995.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_061884.1| hypothetical protein Lxx08840 [Leifsonia xyli subsp. xyli str. CTCB07]). weak similarity to: COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].; hypothetical protein 27736 5172888 pCM2_0029 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220699.1 26819 R 443906 CDS YP_001220700.1 148271138 5172887 complement(28284..28952) 1 NC_009479.1 hypothetical protein, putative DNA-binding protein (N-terminal half: NP_384377.1| hypothetical protein SMc00351 [Sinorhizobium meliloti 1021]; NP_521253.1| PUTATIVE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000] ; C-terminal half: AAS20169.1| hypothetical protein [Arthrobacter aurescens]; CAD60534.1| Cinorf12 protein [Streptomyces cinnamoneus]). smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.; putative DNA-binding protein 28952 5172887 pCM2_0030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-binding protein YP_001220700.1 28284 R 443906 CDS YP_001220701.1 148271139 5172886 complement(29328..29624) 1 NC_009479.1 hypothetical protein 29624 5172886 pCM2_0031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220701.1 29328 R 443906 CDS YP_001220702.1 148271140 5172885 29687..31648 1 NC_009479.1 hypothetical protein, putative helicase (CAD47997.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_122052.1| hypothetical protein pnf230 [Nocardia farcinica IFM 10152]).; hypothetical protein 31648 5172885 pCM2_0032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220702.1 29687 D 443906 CDS YP_001220703.1 148271141 5172884 31937..32707 1 NC_009479.1 putative ATPase, partitioning protein (AAC45808.1| putative plasmid partitioning protein; ParA [Rhodococcus erythropolis]; NP_841536.1| ParA family ATPase [Nitrosomonas europaea ATCC 19718]). pfam00991, ParA, ParA family ATPase.; Function unclear; putative ATPase, partitioning protein 32707 parA 5172884 parA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase, partitioning protein YP_001220703.1 31937 D 443906 CDS YP_001220704.1 148271142 5172883 complement(33340..33681) 1 NC_009479.1 hypothetical protein 33681 5172883 pCM2_0034 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220704.1 33340 R 443906 CDS YP_001220705.1 148271143 5172882 complement(34001..37405) 1 NC_009479.1 conserved hypothetical protein, putative rhs- related protein (NP_733489.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00300025.1| COG3209: Rhs family protein [Geobacter metallireducens GS-15]). pfam05593, RHS_repeat, RHS Repeat. RHS proteins contain extended repeat regions.; putative rhs related protein 37405 rhsA 5172882 rhsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative rhs related protein YP_001220705.1 34001 R 443906 CDS YP_001220706.1 148271144 5172878 complement(39113..39457) 1 NC_009479.1 conserved hypothetical protein, ; YP_062335.1| hypothetical protein Lxx14130 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 39457 5172878 pCM2_0036 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220706.1 39113 R 443906 CDS YP_001220707.1 148271145 5172877 complement(39577..40263) 1 NC_009479.1 conserved hypothetical protein (ZP_00151041.2| COG2135: Uncharacterized conserved protein [Dechloromonas aromatica RCB]; NP_824216.1| hypothetical protein SAV3040 [Streptomyces avermitilis MA-4680]). pfam02586, DUF159, Uncharacterised ACR, COG2135.; hypothetical protein 40263 5172877 pCM2_0037 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220707.1 39577 R 443906 CDS YP_001220708.1 148271146 5172876 40341..41342 1 NC_009479.1 hypothetical protein (YP_120156.1| hypothetical protein nfa39440 [Nocardia farcinica IFM 10152]). weak similarities to VirB11 family proteins (ATPases).; hypothetical protein 41342 5172876 pCM2_0038 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220708.1 40341 D 443906 CDS YP_001220709.1 148271147 5172875 41500..42351 1 NC_009479.1 hypothetical protein 42351 5172875 pCM2_0039 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220709.1 41500 D 443906 CDS YP_001220710.1 148271148 5172874 complement(42684..43211) 1 NC_009479.1 hypothetical protein 43211 5172874 pCM2_0040 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220710.1 42684 R 443906 CDS YP_001220711.1 148271149 5172873 43317..43886 1 NC_009479.1 Hypothetical protein; hypothetical protein 43886 5172873 pCM2_0041 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220711.1 43317 D 443906 CDS YP_001220712.1 148271150 5172872 44636..45133 1 NC_009479.1 hypothetical protein 45133 5172872 pCM2_0042 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220712.1 44636 D 443906 CDS YP_001220713.1 148271151 5172871 complement(45301..45807) 1 NC_009479.1 hypothetical protein pfam07411, DUF1508, Domain of unknown function (DUF1508).; hypothetical protein 45807 5172871 pCM2_0043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220713.1 45301 R 443906 CDS YP_001220714.1 148271152 5172870 46277..46672 1 NC_009479.1 hypothetical protein weak similarity to esterases; hypothetical protein 46672 5172870 pCM2_0044 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220714.1 46277 D 443906 CDS YP_001220715.1 148271153 5172869 46761..46916 1 NC_009479.1 hypothetical protein 46916 5172869 pCM2_0045 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220715.1 46761 D 443906 CDS YP_001220716.1 148271154 5172868 46969..47142 1 NC_009479.1 hypothetical protein 47142 5172868 pCM2_0046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220716.1 46969 D 443906 CDS YP_001220717.1 148271155 5172867 complement(47770..48534) 1 NC_009479.1 hypothetical protein 48534 5172867 pCM2_0047 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220717.1 47770 R 443906 CDS YP_001220718.1 148271156 5172866 complement(48889..49074) 1 NC_009479.1 hypothetical protein 49074 5172866 pCM2_0048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220718.1 48889 R 443906 CDS YP_001220719.1 148271157 5172865 49749..50327 1 NC_009479.1 hypothetical protein 50327 5172865 pCM2_0049 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220719.1 49749 D 443906 CDS YP_001220720.1 148271158 5172864 50621..50809 1 NC_009479.1 hypothetical protein 50809 5172864 pCM2_0050 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220720.1 50621 D 443906 CDS YP_001220721.1 148271159 5172863 complement(51643..51990) 1 NC_009479.1 hypothetical protein 51990 5172863 pCM2_0051 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220721.1 51643 R 443906 CDS YP_001220722.1 148271160 5172862 complement(52086..52940) 1 NC_009479.1 putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin. InterPro: Peptidase trypsin-like serine and cysteine proteases.; Conserved hypothetical protein; hypothetical protein 52940 phpB 5172862 phpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220722.1 52086 R 443906 CDS YP_001220723.1 148271161 5172861 53465..54298 1 NC_009479.1 putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Hypothetical protein; putative extracellular serine protease 54298 phpA 5172861 phpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220723.1 53465 D 443906 CDS YP_001220724.1 148271162 5172860 55371..56213 1 NC_009479.1 putative extracellular serine protease (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07])., pfam00089, Trypsin, Trypsin. , , !! virulence factor !!; Conserved hypothetical protein; hypothetical protein 56213 pat-1 5172860 pat-1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220724.1 55371 D 443906 CDS YP_001220725.1 148271163 5172859 complement(60511..61455) 1 NC_009479.1 hypothetical protein (BAD84024.1| hypothetical protein [Corynebacterium glutamicum]; CAE09114.1| hypothetical protein [Gordonia westfalica]; NP_688285.1| abortive infection protein AbiGII [Streptococcus agalactiae 2603V/R]).; hypothetical protein 61455 5172859 pCM2_0055 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220725.1 60511 R 443906 CDS YP_001220726.1 148271164 5172858 complement(61448..62452) 1 NC_009479.1 putative transcriptional regulator (NP_940396.1| hypothetical protein DIP2072 [Corynebacterium diphtheriae NCTC 13129]; CAE09113.1| hypothetical protein [Gordonia westfalica]).; Conserved hypothetical protein; putative transcriptional regulator 62452 5172858 pCM2_0056 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001220726.1 61448 R 443906 CDS YP_001220727.1 148271165 5172857 complement(63216..63833) 1 NC_009479.1 hypothetical protein 63833 5172857 pCM2_0057 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220727.1 63216 R 443906 CDS YP_001220728.1 148271166 5172856 complement(63936..64526) 1 NC_009479.1 hypothetical protein (AAN24520.1| hypothetical protein BL0701 [Bifidobacterium longum NCC2705]; BAB97855.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 64526 5172856 pCM2_0058 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220728.1 63936 R 443906 CDS YP_001220729.1 148271167 5172855 64866..65033 1 NC_009479.1 conserved hypothetical protein (CAG75796.1| conserved hypothetical protein [Erwinia carotovora subsp. atroseptica SCRI1043]; YP_107569.1| hypothetical protein BPSL0940 [Burkholderia pseudomallei K96243]).; hypothetical protein 65033 5172855 pCM2_0059 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220729.1 64866 D 443906 CDS YP_001220730.1 148271168 5172854 65036..65257 1 NC_009479.1 conserved hypothetical protein (NP_687579.1| hypothetical protein SAG0550 [Streptococcus agalactiae 2603V/R]; NP_766711.1| hypothetical protein bsr0071 [Bradyrhizobium japonicum USDA 110]).; hypothetical protein 65257 5172854 pCM2_0060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220730.1 65036 D 443906 CDS YP_001220731.1 148271169 5172853 66023..66310 1 NC_009479.1 hypothetical protein (NP_696949.1| hypothetical protein BL1802 [Bifidobacterium longum NCC2705]).; hypothetical protein 66310 5172853 pCM2_0061 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220731.1 66023 D 443906 CDS YP_001220732.1 148271170 5172852 complement(66364..66549) 1 NC_009479.1 hypothetical protein 66549 5172852 pCM2_0062 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220732.1 66364 R 443906 CDS YP_001220733.1 148271171 5172851 complement(66598..66933) 1 NC_009479.1 hypothetical protein 66933 5172851 pCM2_0063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220733.1 66598 R 443906 CDS YP_001220734.1 148271172 5172850 67041..67535 1 NC_009479.1 hypothetical protein 67535 5172850 pCM2_0064 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220734.1 67041 D 443906 CDS YP_001220735.1 148271173 5172849 67655..67864 1 NC_009479.1 hypothetical protein (NP_612167.1| YpkF [Corynebacterium jeikeium]).; hypothetical protein 67864 5172849 pCM2_0065 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220735.1 67655 D 443906 CDS YP_001220736.1 148271174 5172848 67890..68732 1 NC_009479.1 conserved hypothetical protein (NP_990877.1| unknown [Achromobacter denitrificans]; ZP_00038266.1| COG2184: Protein involved in cell division [Xylella fastidiosa Dixon]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; hypothetical protein 68732 5172848 pCM2_0066 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220736.1 67890 D 443906 CDS YP_001220737.1 148271175 5172847 complement(68844..69233) 1 NC_009479.1 hypothetical protein 69233 5172847 pCM2_0067 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220737.1 68844 R 443906 CDS YP_001220738.1 148271176 5172846 complement(69233..69568) 1 NC_009479.1 hypothetical protein 69568 5172846 pCM2_0068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220738.1 69233 R 443906 CDS YP_001220739.1 148271177 5172845 complement(69586..69903) 1 NC_009479.1 hypothetical protein 69903 5172845 pCM2_0069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220739.1 69586 R 443906 CDS YP_001220740.1 148271179 5174723 1..1434 1 NC_009480.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1434 dnaA 5174723 dnaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 chromosomal replication initiation protein YP_001220740.1 1 D 443906 CDS YP_001220741.1 148271180 5173799 1978..3129 1 NC_009480.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3129 dnaN 5173799 dnaN Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III subunit beta YP_001220741.1 1978 D 443906 CDS YP_001220742.1 148271181 5174200 3150..4037 1 NC_009480.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase-like protein 4037 gndA1 5174200 gndA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 6-phosphogluconate dehydrogenase-like protein YP_001220742.1 3150 D 443906 CDS YP_001220743.1 148271182 5174954 4045..5259 1 NC_009480.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5259 recF 5174954 recF Clavibacter michiganensis subsp. michiganensis NCPPB 382 recombination protein F YP_001220743.1 4045 D 443906 CDS YP_001220744.1 148271183 5175237 5256..5768 1 NC_009480.1 conserved hypothetical protein (AAS02321.1| hypothetical protein MAP0004 [Mycobacterium avium subsp. paratuberculosis str. k10]; CAF18570.1| CONSERVED HYPOTHETICAL PROTEIN [Corynebacterium glutamicum ATCC 13032]). pfam05258, DUF721, Protein of unknown function (DUF721). This family contains several actinomycete proteins of unknown function.; hypothetical protein 5768 5175237 CMM_0005 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220744.1 5256 D 443906 CDS YP_001220745.1 148271184 5174484 5958..8003 1 NC_009480.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 8003 gyrB 5174484 gyrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA gyrase subunit B YP_001220745.1 5958 D 443906 CDS YP_001220746.1 148271185 5175389 8086..10773 1 NC_009480.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 10773 gyrA 5175389 gyrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA gyrase subunit A YP_001220746.1 8086 D 443906 CDS YP_001220747.1 148271186 5173662 10766..11173 1 NC_009480.1 conserved membrane protein (NP_825500.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00198923.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; putative integral membrane protein 11173 5173662 CMM_0008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative integral membrane protein YP_001220747.1 10766 D 443906 CDS YP_001220748.1 148271187 5174870 complement(11620..12258) 1 NC_009480.1 hypothetical protein 12258 5174870 CMM_0009 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220748.1 11620 R 443906 CDS YP_001220749.1 148271188 5173516 12368..12907 1 NC_009480.1 peptidyl-prolyl cis-trans isomerase B (EC 5.2.1.8) (P77949|PPIB_STRCH Peptidyl-prolyl cis-trans isomerase B (PPIase B) (Rotamase B) (Cyclophilin ScCypB) (S-cyclophilin); ZP_00226474.1| COG0652: Peptidyl-prolyl cis-trans isomerase (rotamase) -cyclophilin family [Kineococcus radiotolerans SRS30216]). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. pfam00160, Pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase.; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase 12907 ppiA 5173516 ppiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptidyl-prolyl cis-trans isomerase YP_001220749.1 12368 D 443906 CDS YP_001220750.1 148271189 5174217 12907..13770 1 NC_009480.1 conserved membrane protein (NP_334528.1| Rhomboid family protein [Mycobacterium tuberculosis CDC1551]; NP_628043.1| putative membrane protein [Streptomyces coelicolor A3(2)]). pfam01694, Rhomboid, Rhomboid family.; Family membership; hypothetical protein 13770 5174217 CMM_0011 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220750.1 12907 D 443906 CDS YP_001220751.1 148271190 5174513 complement(14163..14402) 1 NC_009480.1 conserved membrane protein (NP_788965.1| putative membrane protein [Tropheryma whipplei TW08/27]; CAF18608.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam06781, UPF0233,Uncharacterised protein family (UPF0233).; Hypothetical protein; hypothetical protein 14402 5174513 CMM_0012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220751.1 14163 R 443906 CDS YP_001220752.1 148271191 5173818 14508..15308 1 NC_009480.1 putative sortase (ZP_00226470.1| COG3764: Sortase (surface protein transpeptidase) [Kineococcus radiotolerans SRS30216]; NP_789137.1| putative membrane protein [Tropheryma whipplei TW08/27]). pfam04203,Sortase, Sortase family. The founder member of this family is S.aureus sortase, a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall.; Family membership; putative sortase 15308 5173818 CMM_0013 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sortase YP_001220752.1 14508 D 443906 CDS YP_001220753.1 148271192 5173284 15466..16104 1 NC_009480.1 glutamine amidotransferase class I, putative para-aminobenzoate/ anthranilate synthase glutamine amidotransferase component II [Includes: Para-aminobenzoate synthase glutamine amidotransferase component II (ADC synthase); Anthranilate synthase component II ] (ZP_00209755.1| COG0512: Anthranilate/para-aminobenzoate synthases component II [Magnetospirillum magnetotacticum]; NP_214527.1| pabA [Mycobacterium tuberculosis H37Rv]). CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE (ADC) FROM CHORISMATE AND GLUTAMINE AND ALSO INVOLVED IN THE SYNTHESIS OF ANTHRANILATE. pfam00117, GATase,Glutamine amidotransferase class-I. InterPro: Anthranilate synthase component II/delta crystallin; Specificity unclear; para-aminobenzoate synthetase component II 16104 pabA 5173284 pabA Clavibacter michiganensis subsp. michiganensis NCPPB 382 para-aminobenzoate synthetase component II YP_001220753.1 15466 D 443906 CDS YP_001220754.1 148271193 5175382 complement(16218..17966) 1 NC_009480.1 hypothetical protein 17966 pknB 5175382 pknB Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220754.1 16218 R 443906 CDS YP_001220755.1 148271194 5173494 complement(18101..20008) 1 NC_009480.1 hypothetical protein 20008 pknA 5173494 pknA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220755.1 18101 R 443906 CDS YP_001220756.1 148271195 5173600 complement(20005..21456) 1 NC_009480.1 putative penicillin-binding protein 2 (PBP-2) (ZP_00227926.1| COG0768: Cell division protein FtsI/penicillin-binding protein 2 [Kineococcus radiotolerans SRS30216]; NP_787904.1| penicillin-binding protein [Tropheryma whipplei str. Twist])., pfam00905,Transpeptidase, Penicillin binding protein transpeptidase domain.; High confidence in function and specificity; penicillin-binding protein 21456 pbpA 5173600 pbpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 penicillin-binding protein YP_001220756.1 20005 R 443906 CDS YP_001220757.1 148271196 5175504 complement(21453..22850) 1 NC_009480.1 putative cell division membrane protein (ZP_00227927.1| COG0772: Bacterial cell division membrane protein [Kineococcus radiotolerans SRS30216]; NP_695774.1| protein involved in cell wall formation and stabilization of the FtsZ ring during cell division [Bifidobacterium longum NCC2705]). This is a septum-peptidoglycan biosynthetic protein involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division (By similarity). pfam01098,FTSW_RODA_SPOVE, Cell cycle protein. This entry includes the following members; FtsW, RodA, SpoVE; High confidence in function and specificity; putative cell division membrane protein 22850 ftsW1 5175504 ftsW1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell division membrane protein YP_001220757.1 21453 R 443906 CDS YP_001220758.1 148271197 5174064 complement(22843..24105) 1 NC_009480.1 putative serine/threonine protein phosphatase (ZP_00227928.1| COG0631: Serine/threonine protein phosphatase [Kineococcus radiotolerans SRS30216]; ZP_00058950.1| COG0631: Serine/threonine protein phosphatase [Thermobifida fusca]). pfam00481, PP2C,Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.; Function unclear; putative serine/threonine protein phosphatase 24105 5174064 CMM_0019 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine protein phosphatase YP_001220758.1 22843 R 443906 CDS YP_001220759.1 148271198 5172947 complement(24110..24694) 1 NC_009480.1 conserved hypothetical protein (NP_628032.1| putative secreted protein [Streptomyces coelicolor A3(2)]; CAB02439.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.; hypothetical protein 24694 5172947 CMM_0020 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220759.1 24110 R 443906 CDS YP_001220760.1 148271199 5172918 complement(24691..25422) 1 NC_009480.1 conserved hypothetical protein containing C-terminal FOG:FHA domain (COG1716) (ZP_00227930.1| COG1716: FOG: FHA domain [Kineococcus radiotolerans SRS30216]; NP_695771.1| hypothetical protein with FHA domain [Bifidobacterium longum NCC2705]). pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.; hypothetical protein 25422 5172918 CMM_0021 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220760.1 24691 R 443906 CDS YP_001220761.1 148271200 5175925 25879..28146 1 NC_009480.1 putative membrane protein (ZP_00121629.1| COG2898: Uncharacterized conserved protein [Bifidobacterium longum DJO10A]). pfam04329, DUF470, Family of unknown function (DUF470). This sequence is usually found in association with DUF471 and DUF472, and occasionally also with UPF0104 (pfam03706) in integral membrane proteins. pfam04331,DUF472, Family of unknown function (DUF472).; Function unclear; hypothetical protein 28146 5175925 CMM_0022 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220761.1 25879 D 443906 CDS YP_001220762.1 148271201 5172934 28143..28829 1 NC_009480.1 two-component system response regulator(NP_822457.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00058730.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Thermobifida fusca]). pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 28829 5172934 CMM_0023 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001220762.1 28143 D 443906 CDS YP_001220763.1 148271202 5172963 28837..29955 1 NC_009480.1 putative two-component system sensor kinase (NP_822456.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_823166.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 29955 5172963 CMM_0024 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001220763.1 28837 D 443906 CDS YP_001220764.1 148271203 5172992 complement(29995..30117) 1 NC_009480.1 rpmJ2; smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 30117 rpmJ 5172992 rpmJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L36 YP_001220764.1 29995 R 443906 CDS YP_001220765.1 148271204 5175338 30162..31235 1 NC_009480.1 putative GTPase (NP_962706.1| hypothetical protein MAP3772c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00173773.1| COG0523: Putative GTPases (G3E family) [Methylobacillus flagellatus KT]). weak similarity to: pfam02492, cobW, Cobalamin synthesis protein/P47K.; Function unclear; hypothetical protein 31235 5175338 CMM_0026 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220765.1 30162 D 443906 CDS YP_001220766.1 148271205 5172981 31412..33178 1 NC_009480.1 ATP-dependent DNA helicase recQ (EC 3.6.1.-) (ZP_00198343.2| COG0514: Superfamily II DNA helicase [Kineococcus radiotolerans SRS30216]; ZP_00169039.2| COG0514: Superfamily II DNA helicase [Ralstonia eutropha JMP134]). InterPro: ATP-dependent DNA helicase RecQ pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; ATP-dependent DNA helicase 33178 recQ1 5172981 recQ1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent DNA helicase YP_001220766.1 31412 D 443906 CDS YP_001220767.1 148271206 5173418 33175..33420 1 NC_009480.1 hypothetical protein 33420 5173418 CMM_0028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220767.1 33175 D 443906 CDS YP_001220768.1 148271207 5173028 33677..34654 1 NC_009480.1 glutaminase (L-glutamine amidohydrolase) (ZP_00162219.2| COG2066: Glutaminase [Anabaena variabilis ATCC 29413]; ZP_00026087.1| COG2066: Glutaminase [Ralstonia metallidurans]). pfam04960, Glutaminase,Glutaminase. This family of enzymes deaminates glutamine to glutamate EC:3.5.1.2.; High confidence in function and specificity; putative glutaminase 34654 glsA 5173028 glsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutaminase YP_001220768.1 33677 D 443906 CDS YP_001220769.1 148271208 5175932 complement(34674..35723) 1 NC_009480.1 putative hydrolase/acyltransferase (ZP_00187188.2| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Rubrobacter xylanophilus DSM 9941]; NP_295074.1| hydrolase,alpha/beta hydrolase fold family [Deinococcus radiodurans R1]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. InterPro: Alpha/beta hydrolase fold.; Function unclear; putative hydrolase/acyltransferase 35723 5175932 CMM_0030 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001220769.1 34674 R 443906 CDS YP_001220770.1 148271209 5174522 35841..36227 1 NC_009480.1 putative transcriptional regulator, PadR family (NP_821203.1| putative transcriptional regulator PadR-like family [Streptomyces avermitilis MA-4680]; ZP_00209884.1| COG1695: Predicted transcriptional regulators [Magnetospirillum magnetotacticum]). pfam03551, PadR,Transcriptional regulator PadR-like family.; Specificity unclear; hypothetical protein 36227 5174522 CMM_0031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220770.1 35841 D 443906 CDS YP_001220771.1 148271210 5173015 36305..37552 1 NC_009480.1 Hypothetical protein; hypothetical protein 37552 5173015 CMM_0032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220771.1 36305 D 443906 CDS YP_001220772.1 148271211 5173035 complement(37569..37958) 1 NC_009480.1 conserved hypothetical protein (NP_627276.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00198785.1| COG2514: Predicted ring-cleavage extradiol dioxygenase [Kineococcus radiotolerans SRS30216]). pfam00903, Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein 37958 5173035 CMM_0033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220772.1 37569 R 443906 CDS YP_001220773.1 148271212 5173065 40054..40860 1 NC_009480.1 putative sugar phosphate isomerase/epimerase (ZP_00229027.1| COG1082: Sugar phosphate isomerases/epimerases [Kineococcus radiotolerans SRS30216]; NP_623524.1| Sugar phosphate isomerases/epimerases [Thermoanaerobacter tengcongensis]).; Function unclear; putative sugar phosphate isomerase/epimerase 40860 5173065 CMM_0034 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar phosphate isomerase/epimerase YP_001220773.1 40054 D 443906 CDS YP_001220774.1 148271213 5173049 40857..41966 1 NC_009480.1 putative dehydrogenase/oxidoreductase (ZP_00227973.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_241574.1| BH0708 unknown conserved protein [Bacillus halodurans C-125]). InterPro: Oxidoreductase C-terminal pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Specificity unclear; putative dehydrogenase/oxidoreductase 41966 5173049 CMM_0035 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase/oxidoreductase YP_001220774.1 40857 D 443906 CDS YP_001220775.1 148271214 5173044 42124..43209 1 NC_009480.1 LacI family transcriptional regulator 43209 5173044 CMM_0036 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001220775.1 42124 D 443906 CDS YP_001220776.1 148271215 5174750 complement(45327..45899) 1 NC_009480.1 hypothetical protein (ZP_00230295.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]).; hypothetical protein 45899 5174750 CMM_0037 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220776.1 45327 R 443906 CDS YP_001220777.1 148271216 5175175 complement(47879..48292) 1 NC_009480.1 hypothetical protein 48292 5175175 CMM_0038 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220777.1 47879 R 443906 CDS YP_001220778.1 148271217 5173121 complement(48734..49567) 1 NC_009480.1 putative extracellular serine protease, family S1A (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease 49567 chpE 5173121 chpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001220778.1 48734 R 443906 CDS YP_001220779.1 148271218 5173185 complement(49775..50104) 1 NC_009480.1 hypothetical protein 50104 5173185 CMM_0040 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220779.1 49775 R 443906 CDS YP_001220780.1 148271219 5173189 50376..51356 1 NC_009480.1 putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease 51356 ppaA 5173189 ppaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220780.1 50376 D 443906 CDS YP_001220781.1 148271220 5173735 complement(51503..52507) 1 NC_009480.1 conserved hypothetical protein, putative extracelluar serine protease (NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative extracellular serine protease 52507 ppaB1 5173735 ppaB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220781.1 51503 R 443906 CDS YP_001220782.1 148271221 5174722 52708..53559 1 NC_009480.1 putative pectate lyase (NP_625403.1| putative secreted lyase [Streptomyces coelicolor A3(2)]; CAB40884.1| pectate lyase [Bacillus sp. BP-23]). pfam03211, Pectate_lyase, Pectate lyase.; Function unclear; hypothetical protein 53559 pelA1 5174722 pelA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220782.1 52708 D 443906 CDS YP_001220783.1 148271222 5175587 complement(53883..54896) 1 NC_009480.1 conserved hypothetical protein, putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative extracellular serine protease 54896 ppaC 5175587 ppaC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220783.1 53883 R 443906 CDS YP_001220784.1 148271223 5173320 complement(57043..57396) 1 NC_009480.1 hypothetical protein 57396 5173320 CMM_0045 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220784.1 57043 R 443906 CDS YP_001220785.1 148271224 5173352 61909..62718 1 NC_009480.1 hypothetical protein, putative phage protein (CAD43910.1| hypothetical protein [Lactobacillus casei bacteriophage A2]; ZP_00230220.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858]); hypothetical protein 62718 5173352 CMM_0046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220785.1 61909 D 443906 CDS YP_001220786.1 148271225 5173152 complement(63422..63748) 1 NC_009480.1 hypothetical protein (weak similarity to: NP_858518.1| hypothetical protein [Rhodococcus equi]; YP_056012.1| hypothetical protein PPA1305 [Propionibacterium acnes KPA171202]).; hypothetical protein 63748 5173152 CMM_0047 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220786.1 63422 R 443906 CDS YP_001220787.1 148271226 5173172 complement(64558..64995) 1 NC_009480.1 hypothetical protein 64995 5173172 CMM_0048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220787.1 64558 R 443906 CDS YP_001220788.1 148271227 5173003 65645..67468 1 NC_009480.1 putative beta-N-acetylglucosaminidase (ZP_00187564.2| COG1472: Beta-glucosidase-related glycosidases [Rubrobacter xylanophilus DSM 9941]; NP_626989.1| beta-N-acetylglucosaminidase (putative secreted protein)[Streptomyces coelicolor A3(2)]). ,InterPro: Glycoside hydrolase family 3 N terminal ,pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-N-acetylglucosaminidase 67468 nagA 5173003 nagA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-N-acetylglucosaminidase YP_001220788.1 65645 D 443906 CDS YP_001220789.1 148271228 5175110 complement(67885..68886) 1 NC_009480.1 conserved hypothetical protein, putative extracellular protease (NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; NP_693914.1| hypothetical protein OB2992 [Oceanobacillus iheyensis HTE831]).; Function unclear; putative extracellular protease 68886 ppaB2 5175110 ppaB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular protease YP_001220789.1 67885 R 443906 CDS YP_001220790.1 148271229 5173784 69085..69936 1 NC_009480.1 putative pectate lyase (NP_625403.1| putative secreted lyase [Streptomyces coelicolor A3(2)]; CAB40884.1| pectate lyase [Bacillus sp. BP-23]). pfam03211, Pectate_lyase, Pectate lyase.; Function unclear; hypothetical protein 69936 pelA2 5173784 pelA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220790.1 69085 D 443906 CDS YP_001220791.1 148271230 5175582 complement(70785..71645) 1 NC_009480.1 putative extracellular serine protease, family S1 (chymotrypsin) (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease 71645 chpC 5175582 chpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001220791.1 70785 R 443906 CDS YP_001220792.1 148271231 5175518 74779..75633 1 NC_009480.1 putative extracellular serine protease, family S1 (chymotrypsin) (YP_063162.1| pat1 protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089, Trypsin, Trypsin.; Function unclear; serine protease 75633 chpF 5175518 chpF Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001220792.1 74779 D 443906 CDS YP_001220793.1 148271232 5175219 complement(76541..77545) 1 NC_009480.1 hypothetical protein (NP_954793.1| hypothetical protein [Gordonia westfalica]; NP_940397.1| Hypothetical protein DIP2073 [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 77545 5175219 CMM_0054 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220793.1 76541 R 443906 CDS YP_001220794.1 148271233 5173218 complement(77538..78542) 1 NC_009480.1 conserved hypothetical protein (NP_940396.1| Hypothetical protein DIP2072 [Corynebacterium diphtheriae]; NP_954792.1| hypothetical protein [Gordonia westfalica]).; Function unclear; hypothetical protein 78542 5173218 CMM_0055 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220794.1 77538 R 443906 CDS YP_001220795.1 148271234 5173230 complement(79094..79756) 1 NC_009480.1 hypothetical protein 79756 5173230 CMM_0056 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220795.1 79094 R 443906 CDS YP_001220796.1 148271235 5173235 complement(80653..80916) 1 NC_009480.1 hypothetical protein 80916 5173235 CMM_0057 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220796.1 80653 R 443906 CDS YP_001220797.1 148271236 5173282 82453..82716 1 NC_009480.1 hypothetical protein 82716 5173282 CMM_0058 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220797.1 82453 D 443906 CDS YP_001220798.1 148271237 5173248 82939..83772 1 NC_009480.1 putative extracellular serine protease (AAD09893.2| unknown [Clavibacter michiganensis subsp. michiganensis]; BAA06163.1| SAM-P20 serine protease precursor [Streptomyces albogriseolus]). pfam00089, Trypsin,Trypsin.; Conserved hypothetical protein; putative extracellular serine protease 83772 chpG 5173248 chpG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220798.1 82939 D 443906 CDS YP_001220799.1 148271238 5175664 85126..85584 1 NC_009480.1 hypothetical protein 85584 5175664 CMM_0060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220799.1 85126 D 443906 CDS YP_001220800.1 148271239 5173264 85938..86894 1 NC_009480.1 putative cell filamentation protein (ZP_00038266.1| COG2184: Protein involved in cell division [Xylella fastidiosa Dixon]; NP_990877.1| unknown [Achromobacter denitrificans]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; putative cell filamentation protein 86894 5173264 CMM_0061 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell filamentation protein YP_001220800.1 85938 D 443906 CDS YP_001220801.1 148271240 5174792 91403..91792 1 NC_009480.1 hypothetical protein, putative single-strand binding protein (NP_052579.1| single-strand binding protein homolog Ssb [Corynebacterium glutamicum]; NP_817551.1| gp102 [Mycobacteriophage CJW1]; SSB2_STRCO Single-strand binding protein 2 (SSB 2) (Helix-destabilizing protein 2)). pfam00436, SSB, Single-strand binding protein family. This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.; hypothetical protein 91792 5174792 CMM_0062 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220801.1 91403 D 443906 CDS YP_001220802.1 148271241 5173310 92168..92875 1 NC_009480.1 conserved hypothetical protein (NP_739263.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 92875 5173310 CMM_0063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220802.1 92168 D 443906 CDS YP_001220803.1 148271242 5173334 complement(92944..93639) 1 NC_009480.1 putative hydrolase (Q8TWR2|Y970_METKA Putative HAD-hydrolase MK0970; ZP_00310287.1| COG1011: Predicted hydrolase (HAD superfamily) [Cytophaga hutchinsonii]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase 93639 5173334 CMM_0064 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001220803.1 92944 R 443906 CDS YP_001220804.1 148271243 5173348 complement(93727..94533) 1 NC_009480.1 conserved hypothetical protein, putative phosphotransferase (NP_977552.1| trifolitoxin immunity domain protein [Bacillus cereus ATCC 10987]; ZP_00200969.1| COG3173: Predicted aminoglycoside phosphotransferase [Exiguobacterium sp. 255-15]).; putative phosphotransferase 94533 5173348 CMM_0065 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphotransferase YP_001220804.1 93727 R 443906 CDS YP_001220805.1 148271244 5173317 94677..95309 1 NC_009480.1 partitioning protein (ZP_00174639.2| COG1192: ATPases involved in chromosome partitioning [Crocosphaera watsonii WH 8501]; NP_940697.1| stability protein [Pseudomonas syringae pv. syringae]). , pfam00991, ParA,ParA family ATPase.; High confidence in function and specificity; partitioning protein 95309 parX 5173317 parX Clavibacter michiganensis subsp. michiganensis NCPPB 382 partitioning protein YP_001220805.1 94677 D 443906 CDS YP_001220806.1 148271245 5175476 96096..97265 1 NC_009480.1 putative ATPase (NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]; NP_940101.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]). pfam01637, Arch_ATPase, Archaeal ATPase. This family contain a conserved P-loop motif that is involved in binding ATP.; Function unclear; putative ATPase 97265 5175476 CMM_0067 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001220806.1 96096 D 443906 CDS YP_001220807.1 148271246 5173384 97383..97616 1 NC_009480.1 hypothetical protein 97616 5173384 CMM_0068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220807.1 97383 D 443906 CDS YP_001220808.1 148271247 5173371 complement(97673..98977) 1 NC_009480.1 Na(+)/H(+) antiporter, NhaA family (ZP_00228734.1| COG3004: Na+/H+ antiporter [Kineococcus radiotolerans SRS30216]; ZP_00058667.1| COG3004: Na+/H+ antiporter [Thermobifida fusca]). pfam06965, Na_H_antiport_1, Na+/H+ antiporter 1. This family contains a number of bacterial Na+/H+ antiporter 1 proteins. These are integral membrane proteins that catalyse the exchange of H+ for Na+ in a manner that is highly dependent on the pH.; High confidence in function and specificity; NahA family Na(+)/H(+) antiporter 98977 nhaA1 5173371 nhaA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NahA family Na(+)/H(+) antiporter YP_001220808.1 97673 R 443906 CDS YP_001220809.1 148271248 5175286 complement(99640..102741) 1 NC_009480.1 subtilisin-like serine protease, peptidase family S8A (CAA07000.1| subtilisin-like protease [Lycopersicon esculentum]; NP_717522.1| serine protease, subtilase family [Shewanella oneidensis MR-1]). , pfam05922,Subtilisin_N, Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. , pfam02225,PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.,pfam00082, Peptidase_S8, Subtilase family.; Specificity unclear; subtilisin-like serine protease 102741 sbtA 5175286 sbtA Clavibacter michiganensis subsp. michiganensis NCPPB 382 subtilisin-like serine protease YP_001220809.1 99640 R 443906 CDS YP_001220810.1 148271249 5175632 complement(103428..104384) 1 NC_009480.1 putative serine protease (NP_693914.1| hypothetical protein OB2992 [Oceanobacillus iheyensis HTE831]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]; NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]). pfam00089, Trypsin,Trypsin.; Conserved hypothetical protein; hypothetical protein 104384 ppaE 5175632 ppaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220810.1 103428 R 443906 CDS YP_001220811.1 148271250 5174216 complement(106123..106863) 1 NC_009480.1 conserved hypothetical protein (NP_631356.1| conserved hypothetical protein SC5F8.11c. [Streptomyces coelicolor A3(2)]; AAD31327.1| beta-lactamase-like protein [Mycobacterium smegmatis]). pfam00753,Lactamase_B, Metallo-beta-lactamase superfamily.; Family membership; hypothetical protein 106863 5174216 CMM_0072 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220811.1 106123 R 443906 CDS YP_001220812.1 148271251 5173402 107334..108860 1 NC_009480.1 putative acyl-CoA synthetase (AMP-forming)(ZP_00294061.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Thermobifida fusca]; NP_822779.1| putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme.; Function unclear; putative acyl-CoA synthetase (AMP-forming) 108860 5173402 CMM_0073 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA synthetase (AMP-forming) YP_001220812.1 107334 D 443906 CDS YP_001220813.1 148271252 5174652 112168..112389 1 NC_009480.1 conserved hypothetical protein (NP_687579.1| conserved hypothetical protein [Streptococcus agalactiae 2603V/R]; ZP_00224261.1| hypothetical protein Bucepa02001221 [Burkholderia cepacia R1808]).; hypothetical protein 112389 5174652 CMM_0074 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220813.1 112168 D 443906 CDS YP_001220814.1 148271253 5173438 complement(113031..114005) 1 NC_009480.1 putative extracellular serine protease (NP_779169.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; YP_061793.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease 114005 ppaD 5173438 ppaD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001220814.1 113031 R 443906 CDS YP_001220815.1 148271254 5175387 114879..115307 1 NC_009480.1 hypothetical protein (CAD47974.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein 115307 5175387 CMM_0076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220815.1 114879 D 443906 CDS YP_001220816.1 148271255 5173416 complement(116970..117137) 1 NC_009480.1 hypothetical protein (NP_600530.1| hypothetical protein NCgl1256 [Corynebacterium glutamicum ATCC 13032]; XP_322451.1| predicted protein [Neurospora crassa]); hypothetical protein 117137 5173416 CMM_0077 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220816.1 116970 R 443906 CDS YP_001220817.1 148271256 5174183 117213..118871 1 NC_009480.1 putative NADH oxidase (NP_736949.1| putative pyridine nucleotide-disulphide oxidoreductase [Corynebacterium efficiens YS-314]; NP_654717.1| pyr_redox, Pyridine nucleotide-disulphide oxidoreductase [Bacillus anthracis A2012]). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase. pfam00070,Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. pfam02852, Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. pfam00581, Rhodanese,Rhodanese-like domain.; Specificity unclear; putative NADH oxidase 118871 5174183 CMM_0078 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NADH oxidase YP_001220817.1 117213 D 443906 CDS YP_001220818.1 148271257 5173440 118888..119187 1 NC_009480.1 conserved hypothetical protein (NP_601905.1| rhodanese-related sulfurtransferase [Corynebacterium glutamicum ATCC 13032]; ZP_00058946.1| COG0607: Rhodanese-related sulfurtransferase [Thermobifida fusca]). pfam00581, Rhodanese, Rhodanese-like domain.; Function unclear; hypothetical protein 119187 5173440 CMM_0079 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220818.1 118888 D 443906 CDS YP_001220819.1 148271258 5173431 119184..119501 1 NC_009480.1 conserved hypothetical protein (NP_736667.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; NP_898741.1| conserved hypothetical protein [Rhodococcus erythropolis]). pfam02583, DUF156,Uncharacterised BCR, COG1937.; Function unclear; hypothetical protein 119501 5173431 CMM_0080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220819.1 119184 D 443906 CDS YP_001220820.1 148271259 5173457 complement(119736..120527) 1 NC_009480.1 putative oxidoreductase(ZP_00229014.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; YP_004276.1| short chain dehydrogenase [Thermus thermophilus HB27]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short-chain dehydrogenase/reductase 120527 5173457 CMM_0081 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain dehydrogenase/reductase YP_001220820.1 119736 R 443906 CDS YP_001220821.1 148271260 5173451 complement(120538..122925) 1 NC_009480.1 putative beta-glycosidase (ZP_00229019.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; AAF43783.1| xylosidase/arabinosidase [Thermoanaerobacter ethanolicus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-glucosidase 122925 bglB 5173451 bglB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glucosidase YP_001220821.1 120538 R 443906 CDS YP_001220822.1 148271261 5173828 complement(123070..124908) 1 NC_009480.1 putative beta-glucosidase/beta-xylosidase (ZP_00214214.1| COG1472: Beta-glucosidase-related glycosidases [Burkholderia cepacia R18194]; S53805 beta-glucosidase/xylosidase - Erwinia chrysanthemi). pfam00933,Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.; Specificity unclear; putative beta-glucosidase/beta-xylosidase 124908 bglC 5173828 bglC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glucosidase/beta-xylosidase YP_001220822.1 123070 R 443906 CDS YP_001220823.1 148271262 5173939 complement(124978..125889) 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00225485.1| COG0395: ABC-type sugar transport system,permease component [Kineococcus radiotolerans SRS30216]; AAF37729.1| cellobiose transport permease BglB [Thermobifida fusca]). InterPro: Binding-protein-dependent transport systems inner membrane component pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 125889 5173939 CMM_0084 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001220823.1 124978 R 443906 CDS YP_001220824.1 148271263 5173504 complement(125886..126968) 1 NC_009480.1 putative sugar ABC transporter, permease component (AAF37728.1| cellobiose transport permease BglA [Thermobifida fusca]; ZP_00226174.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_627026.1| putative cellobiose transport permease [Streptomyces coelicolor A3(2)]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 126968 5173504 CMM_0085 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001220824.1 125886 R 443906 CDS YP_001220825.1 148271264 5173547 complement(127043..128320) 1 NC_009480.1 putative sugar ABC transporter, binding protein (ZP_00058384.1| COG1653: ABC-type sugar transport system,periplasmic component [Thermobifida fusca]; T46602 cellobiose/cellotriose binding protein [imported] -Streptomyces reticuli (fragment)). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, binding protein 128320 5173547 CMM_0086 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, binding protein YP_001220825.1 127043 R 443906 CDS YP_001220826.1 148271265 5173477 128542..129288 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00120758.1| COG1309: Transcriptional regulator [Bifidobacterium longum DJO10A]; NP_793102.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 129288 5173477 CMM_0087 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220826.1 128542 D 443906 CDS YP_001220827.1 148271266 5173512 complement(129377..130822) 1 NC_009480.1 putative beta-glucosidase (NP_631601.1| putative beta-glucosidase [Streptomyces coelicolor A3(2)]; NP_826430.1| putative cellobiose hydrolase [Streptomyces avermitilis MA-4680]). InterPro: Glycoside hydrolase family 1; Specificity unclear; putative beta-glucosidase 130822 bglA 5173512 bglA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glucosidase YP_001220827.1 129377 R 443906 CDS YP_001220828.1 148271267 5174035 131048..132076 1 NC_009480.1 putative transcriptional regulator, LacI family (AAP57290.1| CatR [Clavibacter michiganensis subsp. michiganensis]; NP_826160.1| putative LacI-family transcriptional regulator [Streptomyces avermitilis MA-4680]). InterPro: Periplasmic binding proteins and sugar binding domain LacI family pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator 132076 catR 5174035 catR Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001220828.1 131048 D 443906 CDS YP_001220829.1 148271268 5175749 complement(132170..133801) 1 NC_009480.1 tomatinase, glycosyl hydrolase, family 10 (ZP_00192175.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; CAA10112.1| tomatinase [Fusarium oxysporum f. sp. lycopersici]). , pfam00331,Glyco_hydro_10, Glycosyl hydrolase family 10.; High confidence in function and specificity; tomatinase, endo-1,4-beta-glycosidase 133801 tomA 5175749 tomA Clavibacter michiganensis subsp. michiganensis NCPPB 382 tomatinase, endo-1,4-beta-glycosidase YP_001220829.1 132170 R 443906 CDS YP_001220830.1 148271269 5175885 complement(134140..134811) 1 NC_009480.1 putative two-component system response regulator (ZP_00199394.2| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_625364.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 134811 regB 5175885 regB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001220830.1 134140 R 443906 CDS YP_001220831.1 148271270 5174372 complement(134808..135962) 1 NC_009480.1 putative two-component system sensor kinase (ZP_00192164.3| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_827214.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative two-component system sensor kinase 135962 regA 5174372 regA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001220831.1 134808 R 443906 CDS YP_001220832.1 148271271 5175976 complement(135959..138130) 1 NC_009480.1 putative exporter of the RND family (ZP_00229024.1| COG2409: Predicted drug exporters of the RND superfamily [Kineococcus radiotolerans SRS30216]; NP_631580.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]). InterPro: HMGCR/Patched 5TM box; Specificity unclear; RND family transporter 138130 5175976 CMM_0093 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RND family transporter YP_001220832.1 135959 R 443906 CDS YP_001220833.1 148271272 5173566 138337..139557 1 NC_009480.1 cytochrome P450 (ZP_00229013.1| COG2124: Cytochrome P450 [Kineococcus radiotolerans SRS30216]; CAE53708.1| putative cytochrome P450 [Streptomyces peucetius])., ,pfam00067, p450, Cytochrome P450. Cytochrome P450s are involved in the oxidative degradation of various compounds.; Specificity unclear; putative cytochrome P450 139557 cytA 5173566 cytA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome P450 YP_001220833.1 138337 D 443906 CDS YP_001220834.1 148271273 5175085 139554..139751 1 NC_009480.1 putative 3Fe-4S ferredoxin (P18325|FER2_STRGO Ferredoxin 2 (Fd-2); P46374|FAS2_RHOFA Ferredoxin fas2).; Function unclear; putative 3Fe-4S ferredoxin 139751 cytB 5175085 cytB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 3Fe-4S ferredoxin YP_001220834.1 139554 D 443906 CDS YP_001220835.1 148271274 5175202 139748..140950 1 NC_009480.1 Ferredoxin Reductase (P450 system) (NP_822785.1| putative ferredoxin reductase [Streptomyces avermitilis MA-4680]; ZP_00229012.1| COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.; Specificity unclear; putative ferredoxin reductase 140950 cytC 5175202 cytC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ferredoxin reductase YP_001220835.1 139748 D 443906 CDS YP_001220836.1 148271275 5174269 complement(141009..143633) 1 NC_009480.1 putative beta-glucosidase, glycosyl hydrolase family 3 (ZP_00229019.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; AAF43783.1| xylosidase/arabinosidase [Thermoanaerobacter ethanolicus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; glycosyl hydrolase family beta-glucosidase 143633 bglD 5174269 bglD Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycosyl hydrolase family beta-glucosidase YP_001220836.1 141009 R 443906 CDS YP_001220837.1 148271276 5174851 complement(143748..144755) 1 NC_009480.1 putative transcriptional regulator, LacI-family (emb|CAD47864.1| putative LacI-family transcriptional regulator [Arthrobacter nicotinovorans]; NP_963234.1| hypothetical protein MAP4300 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator 144755 5174851 CMM_0098 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001220837.1 143748 R 443906 CDS YP_001220838.1 148271277 5173585 144980..147469 1 NC_009480.1 putative beta-galactosidase/beta-glucuronidase (ZP_00229015.1| COG3250: Beta-galactosidase/beta-glucuronidase [Kineococcus radiotolerans SRS30216]; ZP_00061173.1| COG3250: Beta-galactosidase/ beta-glucuronidase [Clostridium thermocellum ATCC 27405]). InterPro: Glycoside hydrolase family 2 pfam02837,Glyco_hydro_2_N, Glycosyl hydrolases family 2, sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain.; Specificity unclear; hypothetical protein 147469 bglE 5173585 bglE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220838.1 144980 D 443906 CDS YP_001220839.1 148271278 5175285 147484..149739 1 NC_009480.1 putative beta-glucosidase, glycosyl hydrolase family 3 (ZP_00229018.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; ZP_00060124.1| COG1472: Beta-glucosidase- related glycosidases [Clostridium thermocellum ATCC 27405]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; beta-galactosidase 149739 bglF 5175285 bglF Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-galactosidase YP_001220839.1 147484 D 443906 CDS YP_001220840.1 148271279 5174629 149904..151076 1 NC_009480.1 putative beta-glucosidase, glycosyl hydrolase family 1 (ZP_00192144.3| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Kineococcus radiotolerans SRS30216]; CAA52344.1| beta-glucosidase [Streptomyces rochei]). InterPro: Glycoside hydrolase family 1. pfam00232, Glyco_hydro_1, Glycosyl hydrolase family 1.; Specificity unclear; beta-galactosidase 151076 bglG 5174629 bglG Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-galactosidase YP_001220840.1 149904 D 443906 CDS YP_001220841.1 148271280 5173286 151096..152694 1 NC_009480.1 putative beta-galactosidase, glycosyl hydrolase family 35 (ZP_00229011.1| COG1874: Beta-galactosidase [Kineococcus radiotolerans SRS30216]; NP_642855.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]). pfam01301, Glyco_hydro_35, Glycosyl hydrolases family 35.; Specificity unclear; putative beta-galactosidase 152694 bglH 5173286 bglH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-galactosidase YP_001220841.1 151096 D 443906 CDS YP_001220842.1 148271281 5173833 complement(152728..154494) 1 NC_009480.1 putative beta-xylosidase, glycosyl hydrolase family 43 (14-beta-D-xylan xylohydrolase) (NP_244550.1| xylan beta-1,4-xylosidase [Bacillus halodurans C-125]; ZP_00066469.1| COG3507: Beta-xylosidase [Microbulbifer degradans 2-40]). pfam04616, Glyco_hydro_43, Glycosyl hydrolases family 43. cd00057, FA58C, Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.; Specificity unclear; beta-xylosidase glycosyl hydrolase family 43 154494 bglI 5173833 bglI Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-xylosidase glycosyl hydrolase family 43 YP_001220842.1 152728 R 443906 CDS YP_001220843.1 148271282 5174063 154629..156008 1 NC_009480.1 putative sugar permease (MFS superfamily) (ZP_00229022.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; CAD47966.1| hypothetical protein [Arthrobacter nicotinovorans]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; sugar permease 156008 5174063 CMM_0104 Clavibacter michiganensis subsp. michiganensis NCPPB 382 sugar permease YP_001220843.1 154629 D 443906 CDS YP_001220844.1 148271283 5173572 156005..158506 1 NC_009480.1 putative alpha rhamnosidase (ZP_00229021.1| hypothetical protein Krad06000075 [Kineococcus radiotolerans SRS30216]; AAR96046.1| alpha-L-rhamnosidase A [Thermomicrobia bacterium PRI-1686]). , weak similarities to: COG3408, GDB1, Glycogen debranching enzyme; pfam05592, Bac_rhamnosid, Bacterial alpha-L-rhamnosidase. This family consists of bacterial rhamnosidase A and B enzymes. L-Rhamnose is abundant in biomass as a common constituent of glycolipids and glycosides, such as plant pigments, pectic polysaccharides, gums or biosurfactants.; Specificity unclear; putative alpha-rhamnosidase 158506 ramA 5173572 ramA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-rhamnosidase YP_001220844.1 156005 D 443906 CDS YP_001220845.1 148271284 5173716 complement(159396..161624) 1 NC_009480.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 161624 aglA 5173716 aglA Clavibacter michiganensis subsp. michiganensis NCPPB 382 alpha-xylosidase YicI YP_001220845.1 159396 R 443906 CDS YP_001220846.1 148271285 5175505 complement(161748..162659) 1 NC_009480.1 putative sugar ABC transporter, permease compound (NP_822503.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00121009.2| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]).; Specificity unclear; putative sugar ABC transporter, permease compound 162659 5175505 CMM_0107 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease compound YP_001220846.1 161748 R 443906 CDS YP_001220847.1 148271286 5173628 complement(162659..163621) 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_822502.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00227865.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative sugar ABC transporter, permease component 163621 5173628 CMM_0108 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001220847.1 162659 R 443906 CDS YP_001220848.1 148271287 5173664 complement(163695..165053) 1 NC_009480.1 putative sugar ABC transporter, binding protein (NP_822501.1| putative solute-binding lipoprotein [Streptomyces avermitilis MA-4680]; ZP_00227866.1| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, binding protein 165053 5173664 CMM_0109 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, binding protein YP_001220848.1 163695 R 443906 CDS YP_001220849.1 148271288 5173684 165201..166802 1 NC_009480.1 putative xylosidase (NP_693008.1| xylosidase; arabinofuranosidase [Oceanobacillus iheyensis HTE831]; XYLB_BUTFI Xylosidase/arabinosidase [Includes: Beta-xylosidase (1,4-beta-D-xylan xylohydrolase) (Xylan 1,4-beta-xylosidase); Alpha-N-arabinofuranosidase (Arabinosidase)]). pfam04616, Glyco_hydro_43, Glycosyl hydrolases family 43.; Specificity unclear; xylosidase glycosyl hydrolase family protein 166802 5173684 CMM_0110 Clavibacter michiganensis subsp. michiganensis NCPPB 382 xylosidase glycosyl hydrolase family protein YP_001220849.1 165201 D 443906 CDS YP_001220850.1 148271289 5173614 166885..167691 1 NC_009480.1 putative sugar phosphate isomerase/epimerase (ZP_00229027.1| COG1082: Sugar phosphate isomerases/epimerases [Kineococcus radiotolerans SRS30216]; NP_774276.1| bll7636 [Bradyrhizobium japonicum USDA 110]).; Function unclear; putative sugar phosphate isomerase/epimerase 167691 5173614 CMM_0111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar phosphate isomerase/epimerase YP_001220850.1 166885 D 443906 CDS YP_001220851.1 148271290 5173741 167688..168797 1 NC_009480.1 putative dehydrogenase/oxidoreductase (ZP_00227973.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_241574.1| BH0708 unknown conserved protein [Bacillus halodurans C-125]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative dehydrogenase/oxidoreductase 168797 5173741 CMM_0112 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase/oxidoreductase YP_001220851.1 167688 D 443906 CDS YP_001220852.1 148271291 5173695 168891..169622 1 NC_009480.1 putative hydrolase (ZP_00194950.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Mesorhizobium sp. BNC1]; ZP_00024553.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Ralstonia metallidurans]).; Function unclear; putative hydrolase 169622 5173695 CMM_0113 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001220852.1 168891 D 443906 CDS YP_001220853.1 148271292 5173768 169619..170332 1 NC_009480.1 hypothetical protein (NP_624727.1| hypothetical protein SCF51.05 [Streptomyces coelicolor A3(2)]; NP_601349.1| hypothetical protein NCgl2067 [Corynebacterium glutamicum ATCC 13032]). contains COG1413, FOG: HEAT repeat.; hypothetical protein 170332 5173768 CMM_0114 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220853.1 169619 D 443906 CDS YP_001220854.1 148271293 5173085 170415..171371 1 NC_009480.1 putative transcriptional regulator, MerR family (ZP_00191993.3| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_822962.1| putative MerR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00376,MerR, MerR family regulatory protein.; Specificity unclear; hypothetical protein 171371 5173085 CMM_0115 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220854.1 170415 D 443906 CDS YP_001220855.1 148271294 5173806 171496..172086 1 NC_009480.1 putative dienelactone hydrolase (ZP_00210010.1| COG0412: Dienelactone hydrolase and related enzymes [Magnetospirillum magnetotacticum]; ZP_00228563.1| COG0412: Dienelactone hydrolase and related enzymes [Kineococcus radiotolerans SRS30216]). pfam01738, DLH,Dienelactone hydrolase family.; Specificity unclear; putative dienelactone hydrolase 172086 5173806 CMM_0116 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dienelactone hydrolase YP_001220855.1 171496 D 443906 CDS YP_001220856.1 148271295 5173796 complement(172096..173580) 1 NC_009480.1 putative drug-resistance MFS transporter (S70171 integral membrane protein - Streptomyces pristinaespiralis; NP_628206.1| putative integral membrane efflux protein [Streptomyces coelicolor A3(2)]). InterPro: General substrate transporters 14 transmembrane helices; Specificity unclear; putative MFS-type efflux protein 173580 5173796 CMM_0117 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS-type efflux protein YP_001220856.1 172096 R 443906 CDS YP_001220857.1 148271296 5173758 173663..174409 1 NC_009480.1 putative TetR-family transcriptional regulator (NP_631278.1| putative TetR-family transcriptional regulator (NP_631278.1| putative TetR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_792454.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.; Specificity unclear; TetR family transcriptional regulator 174409 5173758 CMM_0118 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220857.1 173663 D 443906 CDS YP_001220858.1 148271297 5173845 complement(174435..175130) 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_827877.1| putative TetR-family transcriptional regulator (NP_827877.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_737549.1| transcription regulator AmtR [Corynebacterium efficiens YS-314]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 175130 5173845 CMM_0119 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220858.1 174435 R 443906 CDS YP_001220859.1 148271298 5173871 complement(175154..178837) 1 NC_009480.1 putative urea amidolyase (NP_923904.1| probable urea amidolyase [Gloeobacter violaceus PCC 7421]; NP_946755.1| putative urea amidolyase [Rhodopseudomonas palustris CGA009]). domain combination of urea hydrolase related proteins: pfam00289, CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain. pfam02786,CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain. pfam02785, Biotin_carb_C, Biotin carboxylase C-terminal domain. pfam02626, AHS2,Allophanate hydrolase subunit 2. pfam02682, AHS1,Allophanate hydrolase subunit 1. pfam00364, Biotin_lipoyl,Biotin-requiring enzyme.; High confidence in function and specificity; putative urea amidolyase 178837 uahA 5173871 uahA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative urea amidolyase YP_001220859.1 175154 R 443906 CDS YP_001220860.1 148271299 5175764 complement(178834..179526) 1 NC_009480.1 conserved hypothetical protein (NP_737324.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00225763.1| COG3665: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 179526 5175764 CMM_0121 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220860.1 178834 R 443906 CDS YP_001220861.1 148271300 5173890 complement(179523..180365) 1 NC_009480.1 conserved hypothetical protein (ZP_00225764.1| COG3665: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_737325.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein 180365 5173890 CMM_0122 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220861.1 179523 R 443906 CDS YP_001220862.1 148271301 5173959 complement(180362..181945) 1 NC_009480.1 putative amino-acid permease, APC family (ZP_00225765.1| COG0531: Amino acid transporters [Kineococcus radiotolerans SRS30216]; NP_827885.1| putative amino acid/metabolite permease [Streptomyces avermitilis MA-4680])., pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease APC family 181945 5173959 CMM_0123 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid permease APC family YP_001220862.1 180362 R 443906 CDS YP_001220863.1 148271302 5173995 complement(182195..185590) 1 NC_009480.1 putative acyl-CoA synthetase (AAR91681.1| ATP/NADPH-dependent carboxylic acid reductase [Nocardia sp. NRRL 5646]; NP_959974.1| FadD9 [Mycobacterium avium subsp. paratuberculosis str. k10])., N-terminal domain: COG1022,FAA1, Long-chain acyl-CoA synthetases (AMP-forming),pfam00501, AMP-binding, AMP-binding enzyme. pfam00550, PP-binding, Phosphopantetheine attachment site. A 4'-phosphopantetheine prosthetic group is attached through a serine. , C-terminal domain: COG3320, COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes acyl_carrier: acyl carrier protein, may be involved in the activation of fatty acids or part of a PKS/NRPS.; Specificity unclear; putative acyl-CoA synthetase 185590 5173995 CMM_0124 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA synthetase YP_001220863.1 182195 R 443906 CDS YP_001220864.1 148271303 5173924 complement(185595..186320) 1 NC_009480.1 putative 4-phosphopantetheinyl transferase (Enterobactin synthetase component D) (NP_822924.1| putative phosphopantetheinyl transferase [Streptomyces avermitilis MA-4680]; AAR92400.1| Sfp-type phosphopantetheinyl transferase [Saccharopolyspora erythraea]).; Function unclear; putative 4-phosphopantetheinyl transferase 186320 5173924 CMM_0125 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 4-phosphopantetheinyl transferase YP_001220864.1 185595 R 443906 CDS YP_001220865.1 148271304 5173975 complement(186504..187316) 1 NC_009480.1 hypothetical protein (EAM74364.1| hypothetical protein KradDRAFT_1431 [Kineococcus radiotolerans SRS30216]; ZP_00413143.1| hypothetical protein ArthDRAFT_2026 [Arthrobacter sp. FB24]).; hypothetical protein 187316 5173975 CMM_0126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220865.1 186504 R 443906 CDS YP_001220866.1 148271305 5174048 complement(187313..187864) 1 NC_009480.1 putative RNA polymerase ECF-subfamily sigma factor (NP_627178.1| putative RNA polymerase sigma factor [Streptomyces coelicolor A3(2)]; YP_121728.1| putative sigma factor [Nocardia farcinica IFM 10152]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. pfam04545,Sigma70_r4, Sigma-70, region 4.; Specificity unclear; RNA polymerase ECF-subfamily sigma factor 187864 sigX 5174048 sigX Clavibacter michiganensis subsp. michiganensis NCPPB 382 RNA polymerase ECF-subfamily sigma factor YP_001220866.1 187313 R 443906 CDS YP_001220867.1 148271306 5173832 188085..188795 1 NC_009480.1 conserved hypothetical protein (XP_390017.1| hypothetical protein FG09841.1 [Gibberella zeae PH-1]; NP_923811.1| hypothetical protein gll0865 [Gloeobacter violaceus PCC 7421]).; hypothetical protein 188795 5173832 CMM_0128 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220867.1 188085 D 443906 CDS YP_001220868.1 148271307 5174019 188801..189469 1 NC_009480.1 putative sortase (NP_631498.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_693584.1| hypothetical protein OB2663 [Oceanobacillus iheyensis HTE831]). cd00004, Sortase, Sortase domain; transpeptidase of Gram-positive bacteria, cleaves surface proteins at the LPXTG motif between Thr and Gly and catalyzes the formation of an amide bond between the carboxyl group of Thr and the amino group of cell-wall crossbridges. In two different classes of sortases the N-terminus either functions as both a signal peptide for secretion and a stop-transfer signal for membrane anchoring, or it contains a signal peptide only and the C-terminus serves as a membrane anchor. pfam04203, Sortase, Sortase family. The founder member of this family is S.aureus sortase, a transpeptidase that attaches surface proteins by the threonine of an LPXTG motif to the cell wall.; Family membership; putative sortase 189469 5174019 CMM_0129 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sortase YP_001220868.1 188801 D 443906 CDS YP_001220869.1 148271308 5174101 complement(189495..189755) 1 NC_009480.1 hypothetical protein (; hypothetical protein 189755 5174101 CMM_0130 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220869.1 189495 R 443906 CDS YP_001220870.1 148271309 5174036 complement(189769..190011) 1 NC_009480.1 hypothetical protein 190011 5174036 CMM_0131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220870.1 189769 R 443906 CDS YP_001220871.1 148271310 5174084 complement(190129..191409) 1 NC_009480.1 hypothetical protein (only weak similarities to RTX toxins (ZP_00116833.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]) and phage capsid proteins (NP_861884.1| Hoc head outer capsid protein [Enterobacteria phage RB69])).; hypothetical protein 191409 5174084 CMM_0132 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220871.1 190129 R 443906 CDS YP_001220872.1 148271311 5174160 191551..192192 1 NC_009480.1 putative cysteine peptidase, family C15 (NP_931479.1| Pyrrolidone- carboxylate peptidase (5-oxoprolyl-peptidase) [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00024570.1| COG2039: Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) [Ralstonia metallidurans]). pfam01470, Peptidase_C15,Pyroglutamyl peptidase.; Function unclear; putative pyroglutamylpeptidase 192192 5174160 CMM_0133 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyroglutamylpeptidase YP_001220872.1 191551 D 443906 CDS YP_001220873.1 148271312 5174137 192438..193625 1 NC_009480.1 putative FAD-dependent monooxygenase (ZP_00216251.1| COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Burkholderia cepacia R18194]; NP_771617.1| blr4977 [Bradyrhizobium japonicum USDA 110]). pfam01360,Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD.; Specificity unclear; hypothetical protein 193625 5174137 CMM_0134 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220873.1 192438 D 443906 CDS YP_001220874.1 148271313 5174203 complement(193999..194973) 1 NC_009480.1 conserved hypothetical protein, weakly ; ZP_00239107.1| GTP pyrophosphokinase [Bacillus cereus G9241])., , pfam04607, RelA_SpoT, Region found in RelA / SpoT proteins.; hypothetical protein 194973 5174203 CMM_0135 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220874.1 193999 R 443906 CDS YP_001220875.1 148271314 5174261 complement(194970..196007) 1 NC_009480.1 hypothetical protein (AAN62299.1| hypothetical protein [Pseudomonas aeruginosa]; AAW89695.1| hypothetical protein, putative phage associated protein [Neisseria gonorrhoeae FA 1090]).; hypothetical protein 196007 5174261 CMM_0136 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220875.1 194970 R 443906 CDS YP_001220876.1 148271315 5174233 complement(196333..197721) 1 NC_009480.1 putative MFS transporter (CAF21275.1| Permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]; NP_961251.1| hypothetical protein MAP2317c [Mycobacterium avium subsp. paratuberculosis str. k10]).; Specificity unclear; putative MFS transporter 197721 5174233 CMM_0137 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS transporter YP_001220876.1 196333 R 443906 CDS YP_001220877.1 148271316 5174332 197794..198540 1 NC_009480.1 putative kinase/phosphotransferase (weak similarity to COG3173, Predicted aminoglycoside phosphotransferase [General function prediction only]; ZP_00200969.1| COG3173: Predicted aminoglycoside phosphotransferase [Exiguobacterium sp. 255-15]; NP_655042.1| Choline_kinase, Choline/ethanolamine kinase [Bacillus anthracis A2012]).; Function unclear; hypothetical protein 198540 5174332 CMM_0138 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220877.1 197794 D 443906 CDS YP_001220878.1 148271317 5174407 complement(198545..198928) 1 NC_009480.1 conserved hypothetical protein (ZP_00074096.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Trichodesmium erythraeum IMS101]; NP_765595.1| mutator protein mutT [Staphylococcus epidermidis ATCC 12228]). pfam00293, NUDIX, NUDIX domain.; Family membership; hypothetical protein 198928 5174407 CMM_0139 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220878.1 198545 R 443906 CDS YP_001220879.1 148271318 5174297 complement(198943..199437) 1 NC_009480.1 transcriptional regulator, MarR family (NP_977771.1| transcriptional regulator, MarR family [Bacillus cereus ATCC 10987]; ZP_00037950.1| COG1846: Transcriptional regulators [Enterococcus faecium]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein 199437 5174297 CMM_0140 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220879.1 198943 R 443906 CDS YP_001220880.1 148271319 5174393 199666..200331 1 NC_009480.1 putative secreted protein 200331 5174393 CMM_0141 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001220880.1 199666 D 443906 CDS YP_001220881.1 148271320 5174429 200413..201393 1 NC_009480.1 hypothetical protein; putative serine peptidase,family S26 (NP_563211.1| signal peptidase type I [Clostridium perfringens str. 13]), , pfam00461,Peptidase_S26, Signal peptidase I.; hypothetical protein 201393 5174429 CMM_0142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220881.1 200413 D 443906 CDS YP_001220882.1 148271321 5174445 201390..202232 1 NC_009480.1 hypothetical protein , cd00110, LamG, Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans.; hypothetical protein 202232 5174445 CMM_0143 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220882.1 201390 D 443906 CDS YP_001220883.1 148271322 5174458 complement(202285..203268) 1 NC_009480.1 conserved hypothetical protein (NP_929594.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; AAM97361.1| RubK [Streptomyces collinus]).; Function unclear; hypothetical protein 203268 5174458 CMM_0144 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220883.1 202285 R 443906 CDS YP_001220884.1 148271323 5174529 complement(203637..204329) 1 NC_009480.1 hypothetical protein (NP_925435.1| unknown protein [Gloeobacter violaceus PCC 7421]).; hypothetical protein 204329 5174529 CMM_0145 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220884.1 203637 R 443906 CDS YP_001220885.1 148271324 5174618 complement(204455..205099) 1 NC_009480.1 hypothetical protein weak similarity to: NP_831063.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; putative peptidase 205099 5174618 CMM_0146 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidase YP_001220885.1 204455 R 443906 CDS YP_001220886.1 148271325 5174464 complement(205099..205731) 1 NC_009480.1 putative signal peptidase I (Leader peptidase I) (AAN08877.1| signal peptidase type I [Leishmania major]; AAF02220.1| signal peptidase type I [Bacillus amyloliquefaciens]). pfam00461, Peptidase_S26, Signal peptidase I.; hypothetical protein 205731 5174464 CMM_0147 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220886.1 205099 R 443906 CDS YP_001220887.1 148271326 5174561 complement(205728..206537) 1 NC_009480.1 hypothetical protein 206537 5174561 CMM_0148 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220887.1 205728 R 443906 CDS YP_001220888.1 148271327 5174646 complement(206653..207351) 1 NC_009480.1 hypothetical protein, weak similarity to: NP_834566.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; hypothetical protein 207351 5174646 CMM_0149 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220888.1 206653 R 443906 CDS YP_001220889.1 148271328 5174699 complement(207498..210902) 1 NC_009480.1 hypothetical protein (EAL12040.1| cell wall surface anchor family protein, putative [Bacillus cereus G9241]; ZP_00117602.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]). , weak similarity to cell surface proteins and invasin.; Conserved hypothetical protein; putative cell wall surface anchor family protein 210902 5174699 CMM_0150 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell wall surface anchor family protein YP_001220889.1 207498 R 443906 CDS YP_001220890.1 148271329 5174769 211308..213179 1 NC_009480.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 213179 dnaK 5174769 dnaK Clavibacter michiganensis subsp. michiganensis NCPPB 382 molecular chaperone DnaK YP_001220890.1 211308 D 443906 CDS YP_001220891.1 148271330 5173896 213176..213829 1 NC_009480.1 heat shock chaperone (HSP-70 cofactor)(NP_695711.1| GrpE protein [Bifidobacterium longum NCC2705]; NP_787877.1| HSP-70 cofactor GrpE [Tropheryma whipplei str. Twist]). Stimulates jointly with dnaJ the ATPAse activity of dnaK. Helps to release ADP from dnaK thus allowing dnaK to recycle more efficiently (By similarity). pfam01025, GrpE, GrpE.; High confidence in function and specificity; heat shock chaperone 213829 grpE 5173896 grpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 heat shock chaperone YP_001220891.1 213176 D 443906 CDS YP_001220892.1 148271331 5174590 213950..214963 1 NC_009480.1 chaperone (NP_789681.1| molecular chaperone DnaJ [Tropheryma whipplei TW08/27]; ZP_00225596.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Kineococcus radiotolerans SRS30216]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. , pfam01556, DnaJ_C, DnaJ C terminal region.; High confidence in function and specificity; chaperone, curved DNA-binding protein 214963 dnaJ1 5174590 dnaJ1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 chaperone, curved DNA-binding protein YP_001220892.1 213950 D 443906 CDS YP_001220893.1 148271332 5174725 214965..215438 1 NC_009480.1 putative transcriptional regulator, MerR family (ZP_00056688.1| COG0789: Predicted transcriptional regulators [Thermobifida fusca]; NP_825664.1| putative HspR protein [Streptomyces avermitilis MA-4680]). PUTATIVE HEAT SHOCK REGULATOR pfam00376, MerR, MerR family regulatory protein.; Specificity unclear; heat shock transcriptional regulator 215438 hspR 5174725 hspR Clavibacter michiganensis subsp. michiganensis NCPPB 382 heat shock transcriptional regulator YP_001220893.1 214965 D 443906 CDS YP_001220894.1 148271333 5175623 215435..216658 1 NC_009480.1 putative methyltransferase (NP_625336.1| conserved hypothetical protein SCG20A.21 [Streptomyces coelicolor A3(2)]; ZP_00138173.1| COG2813: 16S RNA G1207 methylase RsmC [Pseudomonas aeruginosa CBPP-PA14]). , , pfam05175,MTS, Methyltransferase small domain., InterPro: SAM (and some other nucleotide) binding motif.; Function unclear; putative methyltransferase 216658 5175623 CMM_0155 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001220894.1 215435 D 443906 CDS YP_001220895.1 148271334 5174757 216711..217151 1 NC_009480.1 conserved hypothetical protein (ZP_00067078.1| hypothetical protein [Microbulbifer degradans 2-40]; NP_266258.1| hypothetical protein L103661 [Lactococcus lactis subsp. lactis Il1403]).; hypothetical protein 217151 5174757 CMM_0156 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220895.1 216711 D 443906 CDS YP_001220896.1 148271335 5174671 complement(217183..217419) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (ZP_00225419.1| COG3655: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_656871.1| HTH_XRE, Helix-turn-helix XRE-family like proteins [Bacillus anthracis A2012]). smart00530, HTH_XRE,Helix-turn-helix XRE-family like proteins. pfam01381,HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 217419 5174671 CMM_0157 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001220896.1 217183 R 443906 CDS YP_001220897.1 148271336 5174779 complement(217419..218057) 1 NC_009480.1 Hypothetical protein; hypothetical protein 218057 5174779 CMM_0158 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220897.1 217419 R 443906 CDS YP_001220898.1 148271337 5174738 complement(218138..218584) 1 NC_009480.1 conserved hypothetical protein, FAD binding protein (AAQ61023.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472]; NP_738977.1| hypothetical protein [Corynebacterium efficiens YS-314]). pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein.; hypothetical protein 218584 5174738 CMM_0159 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220898.1 218138 R 443906 CDS YP_001220899.1 148271338 5174811 complement(218974..219702) 1 NC_009480.1 hypothetical protein 219702 5174811 CMM_0160 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220899.1 218974 R 443906 CDS YP_001220900.1 148271339 5174967 complement(219867..220895) 1 NC_009480.1 putative LacI-family transcriptional regulator (NP_936186.1| transcriptional regulator [Vibrio vulnificus YJ016]; AAC82367.1| catabolite control protein A [Thermoactinomyces sp. E79]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcriptional regulator 220895 5174967 CMM_0161 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001220900.1 219867 R 443906 CDS YP_001220901.1 148271340 5174872 complement(221482..222105) 1 NC_009480.1 conserved hypothetical protein, possible flavoprotein oxygenase (ZP_00217975.1| COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [Burkholderia cepacia R18194]; NP_244852.1| BH3984 unknown conserved protein [Bacillus halodurans C-125]).; hypothetical protein 222105 5174872 CMM_0162 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220901.1 221482 R 443906 CDS YP_001220902.1 148271341 5175023 222222..223250 1 NC_009480.1 hypothetical protein 223250 5175023 CMM_0163 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220902.1 222222 D 443906 CDS YP_001220903.1 148271342 5175091 223454..224224 1 NC_009480.1 hypothetical protein (only very weak similarities to e. g. ZP_00213268.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R18194]).; hypothetical protein 224224 5175091 CMM_0164 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220903.1 223454 D 443906 CDS YP_001220904.1 148271343 5174980 224275..225177 1 NC_009480.1 putative Fe3+-siderophore ABC transpoter, ATPase component (NP_631450.1| putative ABC-transport protein,ATP-binding component [Streptomyces coelicolor A3(2)]; ZP_00203479.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Anabaena variabilis ATCC 29413]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative Fe3+-siderophore ABC transporter,ATPase component 225177 fhuC 5174980 fhuC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,ATPase component YP_001220904.1 224275 D 443906 CDS YP_001220905.1 148271344 5173486 225174..226163 1 NC_009480.1 putative Fe3+-siderophore ABC transporter, binding protein (NP_631449.1| possible binding-protein-dependent transport lipoprotein [Streptomyces coelicolor A3(2)]; YP_038579.1| iron compound ABC transporter, iron compound-binding protein [Bacillus thuringiensis serovar konkukian str. 97-27]).; Specificity unclear; putative Fe3+-siderophore ABC transporter,binding protein 226163 fhuD 5173486 fhuD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,binding protein YP_001220905.1 225174 D 443906 CDS YP_001220906.1 148271345 5173503 226198..228354 1 NC_009480.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 228354 fhuB 5173503 fhuB Clavibacter michiganensis subsp. michiganensis NCPPB 382 iron-hydroxamate transporter permease subunit YP_001220906.1 226198 D 443906 CDS YP_001220907.1 148271346 5173419 228475..228960 1 NC_009480.1 putative membrane protein (ZP_00299182.1| COG2259: Predicted membrane protein [Geobacter metallireducens GS-15]; ZP_00187970.1| hypothetical protein Rxyl02000785 [Rubrobacter xylanophilus DSM 9941]). weak similarity to: pfam07291, MauE, Methylamine utilisation protein MauE.; hypothetical protein 228960 5173419 CMM_0167a Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220907.1 228475 D 443906 CDS YP_001220908.1 148271347 5175059 229937..231484 1 NC_009480.1 putative two-component system sensor kinase (NP_628759.1| putative two-component system sensor kinase [Streptomyces coelicolor A3(2)]; NP_826056.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 231484 5175059 CMM_0168 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001220908.1 229937 D 443906 CDS YP_001220909.1 148271348 5175107 231511..232173 1 NC_009480.1 putative two-component system response regulator (NP_826055.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00198576.2| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00196, GerE,Bacterial regulatory proteins, luxR family. pfam00072,Response_reg, Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 232173 5175107 CMM_0169 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001220909.1 231511 D 443906 CDS YP_001220910.1 148271349 5175184 232240..232644 1 NC_009480.1 putative tautomerase (ZP_00209270.1| COG1942: Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [Magnetospirillum magnetotacticum]; P94502|YRDN_BACSU Probable tautomerase yrdN). pfam01361,Tautomerase, Tautomerase enzyme. This family includes the enzyme 4-oxalocrotonate tautomerase that catalyses the ketonisation of 2-hydroxymuconate to 2-oxo-3-hexenedioate.; Function unclear; putative tautomerase 232644 5175184 CMM_0170 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tautomerase YP_001220910.1 232240 D 443906 CDS YP_001220911.1 148271350 5175171 complement(232668..233180) 1 NC_009480.1 putative acetyltransferase, GnaT family (NP_899804.1| probable putative acetyltransferase [Chromobacterium violaceum ATCC 12472]; ZP_00058960.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 233180 5175171 CMM_0171 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001220911.1 232668 R 443906 CDS YP_001220912.1 148271351 5175380 complement(233252..234946) 1 NC_009480.1 conserved hypothetical protein (AAD02119.1| unknown [Streptomyces toyocaensis]; ZP_00226047.1| COG0595: Predicted hydrolase of the metallo-beta-lactamase superfamily [Kineococcus radiotolerans SRS30216]). pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily.; Family membership; hypothetical protein 234946 5175380 CMM_0172 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220912.1 233252 R 443906 CDS YP_001220913.1 148271352 5175316 235445..236977 1 NC_009480.1 putative sulfate MFS permease (NP_627488.1| putative integral membrane transporter [Streptomyces coelicolor A3(2)]; NP_862402.1| putative integral membrane transporter [Micrococcus sp. 28]). pfam00916,Sulfate_transp, Sulfate transporter family. TIGRFAM (TIGR00815): sulfate permease sulP. pfam01740, STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; High confidence in function and specificity; putative sulfate MFS permease 236977 sulP 5175316 sulP Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sulfate MFS permease YP_001220913.1 235445 D 443906 CDS YP_001220914.1 148271353 5175729 complement(237042..237698) 1 NC_009480.1 putative Mn2+/Zn2+ ABC-type transporter, ATPase component (NP_624795.1| ABC transport protein, ATP-binding subunit [Streptomyces coelicolor A3(2)]; NP_599281.1| ABC-type transporter, ATPase component [Corynebacterium glutamicum ATCC 13032]). most likely involved in Zn2+ and/or Mn2+ uptake. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative Mn2+/Zn2+ ABC-type transporter, ATPase component 237698 mntA 5175729 mntA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Mn2+/Zn2+ ABC-type transporter, ATPase component YP_001220914.1 237042 R 443906 CDS YP_001220915.1 148271354 5175288 237755..238624 1 NC_009480.1 putative Mn2+/Zn2+ ABC-type transporter, permease component (NP_599280.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]; NP_624794.1| ABC transporter protein, integral membrane subunit [Streptomyces coelicolor A3(2)]).; Specificity unclear; putative Mn2+/Zn2+ ABC-type transporter,permease component 238624 mntB 5175288 mntB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Mn2+/Zn2+ ABC-type transporter,permease component YP_001220915.1 237755 D 443906 CDS YP_001220916.1 148271355 5175656 238675..239907 1 NC_009480.1 conserved hypothetical protein, putatively secreted (NP_599278.1| hypothetical protein NCgl0025 [Corynebacterium glutamicum ATCC 13032]; NP_624793.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 239907 5175656 CMM_0176 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220916.1 238675 D 443906 CDS YP_001220917.1 148271356 5175267 239904..240830 1 NC_009480.1 putative manganese ABC transporter, substrate-binding lipoprotein (NP_599279.1| ABC-type transporter,periplasmic component [Corynebacterium glutamicum ATCC 13032]; NP_624792.1| putative solute-binding lipoprotein [Streptomyces coelicolor A3(2)]). InterPro: Adhesion lipoprotein family pfam01297, SBP_bac_9, Periplasmic solute binding protein family.; Specificity unclear; putative Mn2+/Zn2+ ABC-type transporter,substrate binding protein 240830 mntC 5175267 mntC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Mn2+/Zn2+ ABC-type transporter,substrate binding protein YP_001220917.1 239904 D 443906 CDS YP_001220918.1 148271357 5175684 240866..242077 1 NC_009480.1 conserved hypothetical protein (NP_624791.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_599278.1| hypothetical protein NCgl0025 [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 242077 5175684 CMM_0178 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220918.1 240866 D 443906 CDS YP_001220919.1 148271358 5174892 242217..243596 1 NC_009480.1 NAD-dependent aldehyde dehydrogenase (AAN37492.1| 6-oxohexanoate dehydrogenase; ChnE [Rhodococcus sp. Phi2]; O32507|GABD_DEIRA Succinate-semialdehyde dehydrogenase [NADP+] (SSDH)). pfam00171, Aldedh, Aldehyde dehydrogenase family.; Specificity unclear; NAD-dependent aldehyde dehydrogenase 243596 5174892 CMM_0179 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NAD-dependent aldehyde dehydrogenase YP_001220919.1 242217 D 443906 CDS YP_001220920.1 148271359 5173539 243680..244027 1 NC_009480.1 hypothetical protein 244027 5173539 CMM_0180 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220920.1 243680 D 443906 CDS YP_001220921.1 148271360 5173487 complement(244054..245394) 1 NC_009480.1 putative glycosyltransferase (YP_051468.1| putative glycosyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]; AAN01207.1| putative glycosyltransferase [Lechevalieria aerocolonigenes]). pfam00201, UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase.; Function unclear; putative glycosyltransferase 245394 5173487 CMM_0181 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001220921.1 244054 R 443906 CDS YP_001220922.1 148271361 5173168 complement(245483..245749) 1 NC_009480.1 hypothetical protein 245749 5173168 CMM_0182 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220922.1 245483 R 443906 CDS YP_001220923.1 148271362 5174806 245857..247074 1 NC_009480.1 putative aminotransferase (Q9CBM9|YM94_MYCLE Putative aminotransferase ML1794; NP_625035.1| putative transferase [Streptomyces coelicolor A3(2)]). pfam00155,Aminotran_1_2, Aminotransferase class I and II.; Function unclear; hypothetical protein 247074 5174806 CMM_0183 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220923.1 245857 D 443906 CDS YP_001220924.1 148271363 5174662 247071..248258 1 NC_009480.1 putative methionine synthase II (ZP_00093248.1| COG0620: Methionine synthase II (cobalamin-independent) [Novosphingobium aromaticivorans]; CAF20466.1|; High confidence in function and specificity; hypothetical protein 248258 metE1 5174662 metE1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220924.1 247071 D 443906 CDS YP_001220925.1 148271364 5174727 248261..249622 1 NC_009480.1 O-acetylhomoserine (Thiol)-lyase (EC 2.4.1.49) (Homocysteine synthase) (ZP_00228435.1| COG2873: O-acetylhomoserine sulfhydrylase [Kineococcus radiotolerans SRS30216]; ZP_00293095.1| COG2873: O-acetylhomoserine sulfhydrylase [Thermobifida fusca]). Transforms O-acetylhomoserine into homocysteine. pfam01053,Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme.; High confidence in function and specificity; O-acetylhomoserine (thiol)-lyase 249622 metC 5174727 metC Clavibacter michiganensis subsp. michiganensis NCPPB 382 O-acetylhomoserine (thiol)-lyase YP_001220925.1 248261 D 443906 CDS YP_001220926.1 148271365 5174514 249625..250932 1 NC_009480.1 putative oxidoreductase/monooxygenase (ZP_00228434.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_693700.1| thermophilic desulfurizing enzyme [Oceanobacillus iheyensis HTE831]; AAK63173.1| thiophene oxidizing enzyme [Tsukamurella wratislaviensis]).; Specificity unclear; putative oxidoreductase/monooxygenase 250932 5174514 CMM_0186 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase/monooxygenase YP_001220926.1 249625 D 443906 CDS YP_001220927.1 148271366 5174866 complement(250962..251618) 1 NC_009480.1 putative tetR-family transcriptional regulator (NP_824466.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_960670.1| hypothetical protein MAP1736 [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Bacterial regulatory proteins TetR family pfam00440,TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 251618 5174866 CMM_0187 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220927.1 250962 R 443906 CDS YP_001220928.1 148271367 5174706 251762..253300 1 NC_009480.1 putative multi-drug efflux MFS permease (ZP_00226170.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_739141.1| putative lincomycin-resistance protein [Corynebacterium efficiens YS-314]). pfam00083,Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters efflux_EmrB: drug resistance transport; Specificity unclear; putative multi-drug efflux MFS permease 253300 5174706 CMM_0188 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multi-drug efflux MFS permease YP_001220928.1 251762 D 443906 CDS YP_001220929.1 148271368 5174636 253394..254248 1 NC_009480.1 putative hydrolase (ZP_00191747.2| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_624748.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 254248 5174636 CMM_0189 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001220929.1 253394 D 443906 CDS YP_001220930.1 148271369 5174460 254241..254825 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00191859.2| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_624749.1| putative tetR family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 254825 5174460 CMM_0190 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220930.1 254241 D 443906 CDS YP_001220931.1 148271370 5174692 254831..255229 1 NC_009480.1 Hypothetical protein; hypothetical protein 255229 5174692 CMM_0191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220931.1 254831 D 443906 CDS YP_001220932.1 148271371 5174538 complement(255226..255621) 1 NC_009480.1 putative membrane protein weak similarity to: pfam04235, DUF418, Protein of unknown function (DUF418). Probable integral membrane protein.; Hypothetical protein; hypothetical protein 255621 5174538 CMM_0192 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220932.1 255226 R 443906 CDS YP_001220933.1 148271372 5174490 complement(255632..256381) 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00126009.1| COG1309: Transcriptional regulator [Pseudomonas syringae pv. syringae B728a]; ZP_00192174.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 256381 5174490 CMM_0193 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220933.1 255632 R 443906 CDS YP_001220934.1 148271373 5174402 256493..257581 1 NC_009480.1 putative oxidoreductase (NP_579646.1| putative dehydrogenase [Pyrococcus furiosus DSM 3638]; NP_103783.1| NADH-dependent dyhydrogenase [Mesorhizobium loti MAFF303099]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative oxidoreductase 257581 5174402 CMM_0194 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001220934.1 256493 D 443906 CDS YP_001220935.1 148271374 5174388 257578..258390 1 NC_009480.1 hypothetical protein 258390 5174388 CMM_0195 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220935.1 257578 D 443906 CDS YP_001220936.1 148271375 5174305 258445..259767 1 NC_009480.1 putative sugar ABC transporter, binding protein (P_627687.1| putative secreted sugar-binding protein [Streptomyces coelicolor A3(2)]; YP_014349.1| ABC transporter, substrate-binding protein [Listeria monocytogenes str. 4b F2365]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter, binding protein 259767 5174305 CMM_0196 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, binding protein YP_001220936.1 258445 D 443906 CDS YP_001220937.1 148271376 5174482 259819..260805 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_627686.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; NP_346128.1| ABC transporter, permease protein [Streptococcus pneumoniae TIGR4]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 260805 5174482 CMM_0197 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001220937.1 259819 D 443906 CDS YP_001220938.1 148271377 5174192 260802..261683 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_627685.1| putative sugar-permease [Streptomyces coelicolor A3(2)]; ZP_00192766.2| COG0395: ABC-type sugar transport system, permease component [Mesorhizobium sp. BNC1]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 261683 5174192 CMM_0198 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001220938.1 260802 D 443906 CDS YP_001220939.1 148271378 5174259 complement(261760..262104) 1 NC_009480.1 hypothetical protein (CAF18736.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_898810.1| hypothetical protein PBD2.195 [Rhodococcus erythropolis]).; hypothetical protein 262104 5174259 CMM_0199 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220939.1 261760 R 443906 CDS YP_001220940.1 148271379 5175119 complement(262107..262565) 1 NC_009480.1 hypothetical protein (CAF18735.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_898809.1| hypothetical protein PBD2.194 [Rhodococcus erythropolis]).; hypothetical protein 262565 5175119 CMM_0200 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220940.1 262107 R 443906 CDS YP_001220941.1 148271380 5174227 complement(262610..264466) 1 NC_009480.1 putative glycosyl hydrolase, family 2 (NP_631552.1| putative hydrolase [Streptomyces coelicolor A3(2)]; ZP_00226612.1| COG3250: Beta-galactosidase/beta-glucuronidase [Kineococcus radiotolerans SRS30216]). pfam02837, Glyco_hydro_2_N, Glycosyl hydrolases family 2,sugar binding domain. pfam00703, Glyco_hydro_2, Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.; Specificity unclear; glycoside hydrolase family protein 264466 5174227 CMM_0201 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycoside hydrolase family protein YP_001220941.1 262610 R 443906 CDS YP_001220942.1 148271381 5174094 complement(264565..265752) 1 NC_009480.1 putative dehydrogenase/oxidoreductase (ZP_00226130.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_534841.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Specificity unclear; putative dehydrogenase/oxidoreductase 265752 5174094 CMM_0202 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase/oxidoreductase YP_001220942.1 264565 R 443906 CDS YP_001220943.1 148271382 5174116 complement(265809..268430) 1 NC_009480.1 putative multidrug efflux MFS permease (NP_627382.1| putative membrane transport protein [Streptomyces coelicolor A3(2)]; YP_044552.1| putative transport protein [Staphylococcus aureus subsp. aureus MSSA476]). pfam00529, HlyD, HlyD family secretion protein. actII: Transport protein; Function unclear; RND superfamily drug exporter 268430 5174116 CMM_0203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RND superfamily drug exporter YP_001220943.1 265809 R 443906 CDS YP_001220944.1 148271383 5174033 268492..269082 1 NC_009480.1 putative transcriptional regulator,TetR-family (NP_626528.1| putative TetR-family transcriptional regulator. [Streptomyces coelicolor A3(2)]; NP_350067.1| Transcriptional regulator, AcrR family [Clostridium acetobutylicum ATCC 824]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 269082 5174033 CMM_0204 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220944.1 268492 D 443906 CDS YP_001220945.1 148271384 5174044 complement(269099..270904) 1 NC_009480.1 putative membrane protein (CAF20404.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). weak (N-terminal similarities) to serine proteases (Subtilisin subfamily).; Function unclear; hypothetical protein 270904 5174044 CMM_0205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220945.1 269099 R 443906 CDS YP_001220946.1 148271385 5174011 complement(271019..271876) 1 NC_009480.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 271876 5174011 CMM_0206 Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-hydroxybutyryl-CoA dehydrogenase YP_001220946.1 271019 R 443906 CDS YP_001220947.1 148271386 5173982 complement(272021..272632) 1 NC_009480.1 conserved hypothetical protein (NP_624907.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00296064.1| COG0655: Multimeric flavodoxin WrbA [Methanosarcina barkeri str. fusaro]; NP_882980.1| NADPH-dependent FMN reductase [Bordetella parapertussis 12822]).; Function unclear; hypothetical protein 272632 5173982 CMM_0207 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220947.1 272021 R 443906 CDS YP_001220948.1 148271387 5173965 272795..273652 1 NC_009480.1 putative membrane-associated phospholipid phosphatase 273652 5173965 CMM_0208 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-associated phospholipid phosphatase YP_001220948.1 272795 D 443906 CDS YP_001220949.1 148271388 5173957 273681..273920 1 NC_009480.1 Hypothetical protein; hypothetical protein 273920 5173957 CMM_0209 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220949.1 273681 D 443906 CDS YP_001220950.1 148271389 5173880 273960..274382 1 NC_009480.1 putative protein chain release factor B(NP_875617.1| Protein chain release factor B [Prochlorococcus marinus subsp. marinus str. CCMP1375]; ZP_00225589.1| COG1186: Protein chain release factor B [Kineococcus radiotolerans SRS30216]). pfam00472, RF-1,Peptidyl-tRNA hydrolase domain. This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. InterPro: Class I peptide chain release factor prfB: peptide chain release factor 2; Family membership; hypothetical protein 274382 5173880 CMM_0210 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220950.1 273960 D 443906 CDS YP_001220951.1 148271390 5173825 complement(274410..275459) 1 NC_009480.1 putative monooxygenase (ZP_00225458.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_534605.1| monooxygenase [Agrobacterium tumefaciens str. C58 (U. Washington)]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase 275459 5173825 CMM_0211 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001220951.1 274410 R 443906 CDS YP_001220952.1 148271391 5173912 complement(275539..275694) 1 NC_009480.1 conserved hypothetical protein, putative antitoxin (ZP_00204491.1| COG2161: Antitoxin of toxin-antitoxin stability system [Actinobacillus pleuropneumoniae serovar 1 str. 4074]; ZP_00177056.1| COG2161: Antitoxin of toxin-antitoxin stability system [Crocosphaera watsonii WH 8501]). pfam02604, DUF172, Uncharacterized ACR, COG2161.; hypothetical protein 275694 5173912 CMM_0212 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220952.1 275539 R 443906 CDS YP_001220953.1 148271392 5173783 275764..276108 1 NC_009480.1 conserved hypothetical protein (ZP_00018531.1| hypothetical protein [Chloroflexus aurantiacus]; ZP_00227133.1| COG4898: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 276108 5173783 CMM_0213 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220953.1 275764 D 443906 CDS YP_001220954.1 148271393 5173767 complement(276105..276335) 1 NC_009480.1 conserved hypothetical protein (CAF21348.1| hypothetical protein predicted by Glimmer/Critica [Corynebacterium glutamicum ATCC 13032]; NP_828735.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 276335 5173767 CMM_0214 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220954.1 276105 R 443906 CDS YP_001220955.1 148271394 5173669 complement(276332..276907) 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_624661.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_624835.1| putative TetR family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 276907 5173669 CMM_0215 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220955.1 276332 R 443906 CDS YP_001220956.1 148271395 5173748 277004..278119 1 NC_009480.1 putative Zn-dependant oxidoreductase (XP_387934.1| hypothetical protein FG07758.1 [Gibberella zeae PH-1]; XP_405167.1| hypothetical protein AN1030.2 [Aspergillus nidulans FGSC A4]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zn-dependant oxidoreductase 278119 5173748 CMM_0216 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant oxidoreductase YP_001220956.1 277004 D 443906 CDS YP_001220957.1 148271396 5173691 complement(278116..278919) 1 NC_009480.1 hypothetical protein (NP_898693.1| hypothetical protein PBD2.078 [Rhodococcus erythropolis]).; hypothetical protein 278919 5173691 CMM_0217 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220957.1 278116 R 443906 CDS YP_001220958.1 148271397 5173701 complement(278916..279569) 1 NC_009480.1 hypothetical protein (ZP_00657923.1| hypothetical protein NocaDRAFT_1855 [Nocardioides sp. JS614]); hypothetical protein 279569 5173701 CMM_0218 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220958.1 278916 R 443906 CDS YP_001220959.1 148271398 5173648 279717..280016 1 NC_009480.1 putative sulfurtransferase (NP_266940.1| hypothetical protein L193291 [Lactococcus lactis subsp. lactis Il1403]; NP_601905.1| rhodanese-related sulfurtransferase [Corynebacterium glutamicum ATCC 13032]). pfam00581, Rhodanese, Rhodanese-like domain. InterPro: Rhodanese/cdc25 fold; Function unclear; hypothetical protein 280016 5173648 CMM_0219 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220959.1 279717 D 443906 CDS YP_001220960.1 148271399 5173574 280058..280642 1 NC_009480.1 conserved hypothetical protein (ZP_00228399.1| COG4430: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00274169.1| COG4430: Uncharacterized protein conserved in bacteria [Ralstonia metallidurans CH34]).; hypothetical protein 280642 5173574 CMM_0220 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220960.1 280058 D 443906 CDS YP_001220961.1 148271400 5173599 complement(280668..280982) 1 NC_009480.1 putative multidrug resistance membrane protein (ZP_00293737.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]; AAL07365.1| putative small multidrug resistance protein [Stenotrophomonas maltophilia]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family.; Specificity unclear; putative multidrug resistance membrane protein 280982 5173599 CMM_0221 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug resistance membrane protein YP_001220961.1 280668 R 443906 CDS YP_001220962.1 148271401 5173621 complement(280982..281377) 1 NC_009480.1 putative multidrug resistance membrane protein (ZP_00293737.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]; ZP_00173962.2| COG2076: Membrane transporters of cations and cationic drugs [Methylobacillus flagellatus KT]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family. Several members have been shown to export a range of toxins, including ethidium bromide and quaternary ammonium compounds, through coupling with proton influx. InterPro: Integral membrane protein DUF7; Function unclear; putative multidrug resistance membrane protein 281377 5173621 CMM_0222 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug resistance membrane protein YP_001220962.1 280982 R 443906 CDS YP_001220963.1 148271402 5173568 complement(281510..282169) 1 NC_009480.1 putative phosphatase (NP_533751.1| haloacid dehalogenase-like hydrolase [Agrobacterium tumefaciens str. C58]; ZP_00267448.1| COG0637: Predicted phosphatase/phosphohexomutase [Pseudomonas fluorescens PfO-1]; NP_827006.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. TIGR00099: conserved hypothetical prote; Function unclear; putative phosphatase 282169 5173568 CMM_0223 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001220963.1 281510 R 443906 CDS YP_001220964.1 148271403 5174849 282255..283451 1 NC_009480.1 putative glycosyl transferase (AAM70336.1| CalG1 [Micromonospora echinospora]; BAD08357.1| glycosyltransferase [Streptomyces halstedii]). pfam03033,Glyco_transf_28, Glycosyltransferase family 28 N-terminal domain. This N-terminal domain contains the acceptor binding site and likely membrane association site. pfam04101, Glyco_tran_28_C, Glycosyltransferase family 28 C-terminal domain.; Specificity unclear; putative glycosyl transferase 283451 5174849 CMM_0224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001220964.1 282255 D 443906 CDS YP_001220965.1 148271404 5173549 283730..284890 1 NC_009480.1 putative sarcosine oxidase (ZP_00227998.1| COG0665: Glycine/D-amino acid oxidases (deaminating) [Kineococcus radiotolerans SRS30216]; Q827H4|MSOX_STRAW Monomeric sarcosine oxidase (MSOX)). pfam01266, DAO, FAD dependent oxidoreductase.; Specificity unclear; putative sarcosine oxidase 284890 5173549 CMM_0225 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sarcosine oxidase YP_001220965.1 283730 D 443906 CDS YP_001220966.1 148271405 5173506 complement(284921..285598) 1 NC_009480.1 hypothetical protein 285598 5173506 CMM_0226 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220966.1 284921 R 443906 CDS YP_001220967.1 148271406 5173527 complement(285732..286691) 1 NC_009480.1 putative acetyl xylan esterase (NP_822477.1| putative cephalosporin C deacetylase [Streptomyces avermitilis MA-4680]; NP_107393.1| acetyl xylan esterase [Mesorhizobium loti MAFF303099]). , pfam05448, AXE1,Acetyl xylan esterase (AXE1).; Specificity unclear; putative acetyl xylan esterase 286691 5173527 CMM_0227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyl xylan esterase YP_001220967.1 285732 R 443906 CDS YP_001220968.1 148271407 5173489 complement(286773..287369) 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_822813.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; CAB07159.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)[Mycobacterium tuberculosis H37Rv]). pfam00440,TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 287369 5173489 CMM_0228 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001220968.1 286773 R 443906 CDS YP_001220969.1 148271408 5173461 complement(287456..289510) 1 NC_009480.1 putative acyl esterase (NP_826040.1| hypothetical protein SAV4863 [Streptomyces avermitilis MA-4680]; NP_105843.1|; Function unclear; putative acyl esterase 289510 5173461 CMM_0229 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl esterase YP_001220969.1 287456 R 443906 CDS YP_001220970.1 148271409 5173433 complement(289507..291240) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_790103.1| peptide ABC transporter, ATP-binding protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_415350.1| putative ATP-binding component of a transport system; putative oligopeptide transport protein (ABC superfamily, atp_bind) [Escherichia coli K12]). cd00267,ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain (twice).; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 291240 5173433 CMM_0230 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001220970.1 289507 R 443906 CDS YP_001220971.1 148271410 5173387 complement(291237..292118) 1 NC_009480.1 putative peptide ABC transporter, permease component (CAG20639.1| hypothetical ABC transporter permease [Photobacterium profundum]; NP_846941.1| oligopeptide ABC transporter, oligopeptide-binding protein [Bacillus anthracis str. Ames]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; High confidence in function and specificity; putative peptide ABC transporter, permease component 292118 5173387 CMM_0231 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001220971.1 291237 R 443906 CDS YP_001220972.1 148271411 5173442 complement(292115..293134) 1 NC_009480.1 putative peptide ABC transporter, permease component (CAG20638.1| hypothetical ABC transporter,permease protein [Photobacterium profundum]; NP_085756.1| dipeptide transport system permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 293134 5173442 CMM_0232 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001220972.1 292115 R 443906 CDS YP_001220973.1 148271412 5173326 complement(293131..294786) 1 NC_009480.1 putative peptide ABC transporter, substrate-binding protein (CAG20637.1| hypothetical ABC transporter,periplasmic solute-binding protein, family 5 [Photobacterium profundum]; NP_357196.1| AGR_L_2824p [Agrobacterium tumefaciens str. C58]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 294786 5173326 CMM_0233 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001220973.1 293131 R 443906 CDS YP_001220974.1 148271413 5173380 complement(294887..295393) 1 NC_009480.1 hypothetical protein 295393 5173380 CMM_0234 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220974.1 294887 R 443906 CDS YP_001220975.1 148271414 5173311 complement(295483..296382) 1 NC_009480.1 hypothetical protein 296382 5173311 CMM_0235 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220975.1 295483 R 443906 CDS YP_001220976.1 148271415 5173406 complement(296480..298468) 1 NC_009480.1 conserved membrane protein, putative amino acid permease, APC family (NP_825946.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00110752.1| COG0531: Amino acid transporters [Nostoc punctiforme]).; Conserved hypothetical protein; hypothetical protein 298468 5173406 CMM_0236 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220976.1 296480 R 443906 CDS YP_001220977.1 148271416 5173257 complement(298681..299049) 1 NC_009480.1 hypothetical protein 299049 5173257 CMM_0237 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220977.1 298681 R 443906 CDS YP_001220978.1 148271417 5173338 complement(299132..300355) 1 NC_009480.1 putative efflux MFS permease (NP_827094.1| putative bicyclomycin resistance protein [Streptomyces avermitilis MA-4680]; NP_830072.1| Bicyclomycin resistance protein [Bacillus cereus ATCC 14579]). pfam00083, Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00710): drug resistance transporter; Specificity unclear; putative bicyclomycin efflux MFS permease 300355 5173338 CMM_0238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bicyclomycin efflux MFS permease YP_001220978.1 299132 R 443906 CDS YP_001220979.1 148271418 5173267 300554..300775 1 NC_009480.1 hypothetical protein 300775 5173267 CMM_0239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220979.1 300554 D 443906 CDS YP_001220980.1 148271419 5173293 300958..301788 1 NC_009480.1 putative short-chain alcohol dehydrogenase (ZP_00226165.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00193775.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Mesorhizobium sp. BNC1]). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain alcohol dehydrogenase 301788 5173293 CMM_0240 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain alcohol dehydrogenase YP_001220980.1 300958 D 443906 CDS YP_001220981.1 148271420 5173240 complement(301826..302098) 1 NC_009480.1 Hypothetical protein; hypothetical protein 302098 5173240 CMM_0241 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220981.1 301826 R 443906 CDS YP_001220982.1 148271421 5173191 complement(302169..302795) 1 NC_009480.1 Putative methylated-DNA-protein-cysteine methyltransferase (O-6-methylguanine-DNA-alkyltransferase) (ZP_00228907.1| COG0350: Methylated DNA-protein cysteine methyltransferase [Kineococcus radiotolerans SRS30216]; NP_602199.1| methylated DNA-protein cysteine methyltransferase [Corynebacterium glutamicum ATCC 13032]). pfam02870, Methyltransf_1N, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain. pfam01035, Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain.; Family membership; 6-O-methylguanine-DNA methyltransferase 302795 ogtA 5173191 ogtA Clavibacter michiganensis subsp. michiganensis NCPPB 382 6-O-methylguanine-DNA methyltransferase YP_001220982.1 302169 R 443906 CDS YP_001220983.1 148271422 5175121 complement(302792..303322) 1 NC_009480.1 DNA-directed RNA polymerase specialized sigma subunit, ECF family (ZP_00228908.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]; ZP_00293287.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Thermobifida fusca]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. pfam04545,Sigma70_r4, Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; hypothetical protein 303322 sigY 5175121 sigY Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220983.1 302792 R 443906 CDS YP_001220984.1 148271423 5175919 303648..304385 1 NC_009480.1 putative two-component system response regulator (NP_825375.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; NP_628202.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. InterPro: Response regulator receiver domain; Function unclear; putative two-component system response regulator 304385 5175919 CMM_0244 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001220984.1 303648 D 443906 CDS YP_001220985.1 148271424 5173208 304664..305953 1 NC_009480.1 hypothetical protein, , only weak N-terminal similarities to RTX toxins.; hypothetical protein 305953 5173208 CMM_0245 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220985.1 304664 D 443906 CDS YP_001220986.1 148271425 5173220 306397..310155 1 NC_009480.1 hypothetical protein 310155 5173220 CMM_0246 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220986.1 306397 D 443906 CDS YP_001220987.1 148271426 5173126 310377..311591 1 NC_009480.1 putative oxidoreductase/dehydrogenase (NP_823001.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; ZP_00226131.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894,GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain. InterPro: Oxidoreductase C-terminal redox_disulf_1: redox-active disulfide; Function unclear; putative oxidoreductase/dehydrogenase 311591 5173126 CMM_0247 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase/dehydrogenase YP_001220987.1 310377 D 443906 CDS YP_001220988.1 148271427 5173177 311642..312358 1 NC_009480.1 conserved membrane protein (NP_625282.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_823511.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 312358 5173177 CMM_0248 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220988.1 311642 D 443906 CDS YP_001220989.1 148271428 5173108 312537..313244 1 NC_009480.1 conserved hypothetical protein (NP_823510.1| hypothetical protein SAV2334 [Streptomyces avermitilis MA-4680]; ZP_00171355.2| COG4549: Uncharacterized protein conserved in bacteria [Ralstonia eutropha JMP134]). Mtu_fam_11: Mycobacterium tuberculosis p; hypothetical protein 313244 5173108 CMM_0249 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220989.1 312537 D 443906 CDS YP_001220990.1 148271429 5173161 313241..314725 1 NC_009480.1 conserved membrane protein (ZP_00126878.2| COG3182: Uncharacterized iron-regulated membrane protein [Pseudomonas syringae pv. syringae B728a]; ZP_00293139.1| COG3182: Uncharacterized iron-regulated membrane protein [Thermobifida fusca]; YP_049875.1| putative iron-regulated membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam03929, DUF337, Uncharacterized iron-regulated membrane protein (DUF337). bcl-2: Apoptosis regulator; Conserved hypothetical protein; hypothetical protein 314725 5173161 CMM_0250 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220990.1 313241 D 443906 CDS YP_001220991.1 148271430 5173052 complement(314775..315788) 1 NC_009480.1 putative LacI-family transcriptional regulator (ZP_00049013.1| COG1609: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_823745.1| putative LacI-family transcriptional regulator Streptomyces avermitilis MA-4680]). pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The LacI family of proteins consist of transcriptional regulators related to the lac repressor.; Specificity unclear; LacI family transcriptional regulator 315788 5173052 CMM_0251 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001220991.1 314775 R 443906 CDS YP_001220992.1 148271431 5173145 complement(315851..316573) 1 NC_009480.1 conserved membrane protein (ZP_00239707.1| integral membrane protein [Bacillus cereus G9241]; NP_825757.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 316573 5173145 CMM_0252 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220992.1 315851 R 443906 CDS YP_001220993.1 148271432 5173067 complement(316624..317823) 1 NC_009480.1 putative glycosyl transferase (ZP_00329344.1| COG0438: Glycosyltransferase [Moorella thermoacetica ATCC 39073]; NP_294949.1| mannosyltransferase, putative [Deinococcus radiodurans R1]). pfam00534, Glycos_transf_1,Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates,including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Function unclear; hypothetical protein 317823 5173067 CMM_0253 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220993.1 316624 R 443906 CDS YP_001220994.1 148271433 5173094 complement(317976..318227) 1 NC_009480.1 hypothetical protein (NP_821697.1| hypothetical protein SAV522 [Streptomyces avermitilis MA-4680]; NP_436996.1| HYPOTHETICAL PROTEIN SMb20474 [Sinorhizobium meliloti 1021]).; hypothetical protein 318227 5173094 CMM_0254 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220994.1 317976 R 443906 CDS YP_001220995.1 148271434 5173018 318363..319832 1 NC_009480.1 putative efflux MFS permease (ZP_00190381.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_628802.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr, Sugar (and other) transporter. efflux_EmrB: drug resistance transport; Specificity unclear; putative MFS permease 319832 5173018 CMM_0255 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001220995.1 318363 D 443906 CDS YP_001220996.1 148271435 5173045 complement(320052..320687) 1 NC_009480.1 conserved hypothetical protein (ZP_00280805.1| COG2907: Predicted NAD/FAD-binding protein [Burkholderia fungorum LB400]; ZP_00150213.1| COG2907: Predicted NAD/FAD-binding protein [Dechloromonas aromatica RCB]).; Function unclear; hypothetical protein 320687 5173045 CMM_0256 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220996.1 320052 R 443906 CDS YP_001220997.1 148271436 5173002 complement(320698..321345) 1 NC_009480.1 putative transcriptional regulator, MerR family (NP_629684.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_828502.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]). smart00422, HTH_MERR, helix_turn_helix, mercury resistance.; Specificity unclear; MerR family transcriptional regulator 321345 5173002 CMM_0257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MerR family transcriptional regulator YP_001220997.1 320698 R 443906 CDS YP_001220998.1 148271437 5173037 complement(321541..322134) 1 NC_009480.1 conserved hypothetical protein (NP_901178.1| probable transmembrane protein [Chromobacterium violaceum ATCC 12472]; NP_623732.1| conserved hypothetical protein [Thermoanaerobacter tengcongensis]).; hypothetical protein 322134 5173037 CMM_0258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001220998.1 321541 R 443906 CDS YP_001220999.1 148271438 5172950 322313..322837 1 NC_009480.1 putative membrane protein involved in chromosome condensation (AAK73171.1| putative CrcB-like protein [Brevibacterium sp. HCU]; AAL42476.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]) pfam02537, CRCB, CrcB-like protein. CRCB is a putative integral membrane protein possibly involved in chromosome condensation. crcB: crcB protein; Function unclear; putative membrane protein involved in chromosome condensation 322837 crcB1 5172950 crcB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane protein involved in chromosome condensation YP_001220999.1 322313 D 443906 CDS YP_001221000.1 148271439 5173467 322834..323214 1 NC_009480.1 putative membrane protein involved in chromosome condensation (Q9FC37|CRB2_STRCO Protein crcB homolog 2; ZP_00043418.1| COG0239: Integral membrane protein possibly involved in chromosome condensation [Magnetococcus sp. MC-1]). pfam02537, CRCB, CrcB-like protein. CRCB is a putative integral membrane protein possibly involved in chromosome condensation. crcB: crcB protein; Function unclear; putative membrane protein involved in chromosome condensation 323214 crcB2 5173467 crcB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane protein involved in chromosome condensation YP_001221000.1 322834 D 443906 CDS YP_001221001.1 148271440 5172975 323211..323687 1 NC_009480.1 putative acetyltransferase (NP_294404.1| hypothetical protein [Deinococcus radiodurans]; ZP_00186452.1| COG1246: N-acetylglutamate synthase and related acetyltransferases [Rubrobacter xylanophilus DSM 9941]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 323687 5172975 CMM_0261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221001.1 323211 D 443906 CDS YP_001221002.1 148271441 5172966 323697..324284 1 NC_009480.1 putative NTP pyrophosphohydrolases (ZP_00188287.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Rubrobacter xylanophilus DSM 9941]; ZP_00330170.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Moorella thermoacetica ATCC 39073]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolases 324284 5172966 CMM_0262 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphohydrolases YP_001221002.1 323697 D 443906 CDS YP_001221003.1 148271442 5173907 complement(324294..325301) 1 NC_009480.1 putative D-alanine-D-alanine ligase (ZP_00137683.2| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00212274.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Burkholderia cepacia R18194]). Cell wall formation (By similarity). pfam01820,Dala_Dala_ligas, D-ala D-ala ligase. InterPro: D-alanine--D-alanine ligase.; High confidence in function and specificity; putative D-alanine--D-alanine ligase 325301 ddlA 5173907 ddlA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative D-alanine--D-alanine ligase YP_001221003.1 324294 R 443906 CDS YP_001221004.1 148271443 5174994 complement(325348..326058) 1 NC_009480.1 conserved hypothetical protein (NP_630443.1| hypothetical protein SC3A7.19 [Streptomyces coelicolor A3(2)]; ZP_00034039.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia fungorum]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; hypothetical protein 326058 5174994 CMM_0264 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221004.1 325348 R 443906 CDS YP_001221005.1 148271444 5172976 complement(326061..326615) 1 NC_009480.1 conserved hypothetical protein (NP_631701.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00049640.1| COG0262: Dihydrofolate reductase [Magnetospirillum magnetotacticum]). pfam01872, RibD_C,RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis.; Family membership; hypothetical protein 326615 5172976 CMM_0265 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221005.1 326061 R 443906 CDS YP_001221006.1 148271445 5175583 326881..328224 1 NC_009480.1 conserved membrane protein (NP_791711.1| membrane protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; NP_901555.1| hypothetical protein CV1885 [Chromobacterium violaceum ATCC 12472]).; Conserved hypothetical protein; hypothetical protein 328224 5175583 CMM_0266 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221006.1 326881 D 443906 CDS YP_001221007.1 148271446 5172923 328221..329078 1 NC_009480.1 putative transcriptional regulator, RpiR family (NP_781945.1| transcriptional regulator, rpiR family [Clostridium tetani E88]; NP_519498.1| CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]). pfam01418,HTH_6, Helix-turn-helix domain, rpiR family. This domain contains a helix-turn-helix motif. The best characterised member of this family is RpiR, a regulator of the expression of rpiB gene. pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins.; Specificity unclear; RpiR family transcriptional regulator 329078 5172923 CMM_0267 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RpiR family transcriptional regulator YP_001221007.1 328221 D 443906 CDS YP_001221008.1 148271447 5173012 329139..330083 1 NC_009480.1 putative hydroxyacid dehydrogenase (ZP_00127342.1| COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Pseudomonas syringae pv. syringae B728a]; YP_044837.1| putative 3-hydroxyisobutyrate dehydrogenase [Acinetobacter sp. ADP1]). pfam03446, NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase.; Specificity unclear; putative hydroxyacid dehydrogenase 330083 5173012 CMM_0268 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydroxyacid dehydrogenase YP_001221008.1 329139 D 443906 CDS YP_001221009.1 148271448 5175506 330080..331660 1 NC_009480.1 putative aldehyde dehydrogenase (ZP_00166104.1| COG1012: NAD-dependent aldehyde dehydrogenases [Ralstonia eutropha JMP134]; NP_791704.1| aldehyde dehydrogenase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor. InterPro: Aldehyde dehydrogenase family.; Specificity unclear; putative aldehyde dehydrogenase 331660 5175506 CMM_0269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldehyde dehydrogenase YP_001221009.1 330080 D 443906 CDS YP_001221010.1 148271449 5173127 331874..333112 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (ZP_00192200.3| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_625350.1| putative sugar transport sugar binding protein [Streptomyces coelicolor A3(2)]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter, substrate binding protein 333112 5173127 CMM_0270 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001221010.1 331874 D 443906 CDS YP_001221011.1 148271450 5175681 333112..334101 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00226127.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]; NP_625351.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter, permease component 334101 5175681 CMM_0271 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221011.1 333112 D 443906 CDS YP_001221012.1 148271451 5175281 334094..334969 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00226128.1| COG0395: ABC-type sugar transport system,permease component [Kineococcus radiotolerans SRS30216]; NP_625352.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter, permease component 334969 5175281 CMM_0272 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221012.1 334094 D 443906 CDS YP_001221013.1 148271452 5173236 335052..335822 1 NC_009480.1 conserved hypothetical protein (ZP_00226129.1| COG4813: Trehalose utilization protein [Kineococcus radiotolerans SRS30216]; NP_693487.1| hypothetical protein OB2566 [Oceanobacillus iheyensis HTE831]). pfam06283, DUF1037, Protein of unknown function (DUF1037). This family consists of several bacterial ThuA like proteins. The function of the family is unknown.; Function unclear; trehalose utilization-related protein 335822 5173236 CMM_0273 Clavibacter michiganensis subsp. michiganensis NCPPB 382 trehalose utilization-related protein YP_001221013.1 335052 D 443906 CDS YP_001221014.1 148271453 5173176 335819..337048 1 NC_009480.1 putative dehydrogenase (ZP_00226130.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_534841.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family,C-terminal alpha/beta domain.; Function unclear; putative dehydrogenase 337048 5173176 CMM_0274 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase YP_001221014.1 335819 D 443906 CDS YP_001221015.1 148271454 5172931 337069..338382 1 NC_009480.1 transcriptional regulator, ROK family (ZP_00227613.1| COG1940: Transcriptional regulator/sugar kinase [Kineococcus radiotolerans SRS30216]; NP_623501.1| Transcriptional regulator [Thermoanaerobacter tengcongensis]). InterPro: ROK family ROK_glcA_fam: ROK family protein (puta; Specificity unclear; ROK family transcriptional regulator 338382 5172931 CMM_0275 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ROK family transcriptional regulator YP_001221015.1 337069 D 443906 CDS YP_001221016.1 148271455 5173529 338379..339035 1 NC_009480.1 conserved hypothetical protein, putative phosphatase (ZP_00163802.1| hypothetical protein Selo236801 [Synechococcus elongatus PCC 7942]; NP_945802.1| possible hydrolases/phosphatases [Rhodopseudomonas palustris CGA009]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Family membership; hypothetical protein 339035 5173529 CMM_0276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221016.1 338379 D 443906 CDS YP_001221017.1 148271456 5173315 complement(339073..340074) 1 NC_009480.1 Hypothetical protein; hypothetical protein 340074 5173315 CMM_0277 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221017.1 339073 R 443906 CDS YP_001221018.1 148271457 5173673 340257..340847 1 NC_009480.1 putative chorismate mutase (ZP_00041424.1| COG1605: Chorismate mutase [Xylella fastidiosa Ann-1]; ZP_00217335.1| COG1605: Chorismate mutase [Burkholderia cepacia R18194]). pfam01817, Chorismate_mut, Chorismate mutase. InterPro: Chorismate mutase; Family membership; putative chorismate mutase 340847 5173673 CMM_0278 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chorismate mutase YP_001221018.1 340257 D 443906 CDS YP_001221019.1 148271458 5174944 complement(340959..341297) 1 NC_009480.1 conserved membrane protein (CAB02345.1| PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_825933.1| hypothetical protein SAV4756 [Streptomyces avermitilis MA-4680]). pfam02694,UPF0060, Uncharacterized BCR, YnfA/UPF0060 family.; Conserved hypothetical protein; hypothetical protein 341297 5174944 CMM_0279 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221019.1 340959 R 443906 CDS YP_001221020.1 148271459 5173443 complement(341356..341847) 1 NC_009480.1 conserved hypothetical protein (NP_828610.1| hypothetical protein SAV7434 [Streptomyces avermitilis MA-4680]; ZP_00225717.1| hypothetical protein Krad06004549 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 341847 5173443 CMM_0280 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221020.1 341356 R 443906 CDS YP_001221021.1 148271460 5173095 complement(342105..342899) 1 NC_009480.1 putative acetyltransferase (NP_295640.1| hypothetical protein [Deinococcus radiodurans R1]; NP_822402.1| hypothetical protein SAV1227 [Streptomyces avermitilis MA-4680]; NP_935421.1| acetyltransferase [Vibrio vulnificus YJ016]). weak similarities to: COG3153,COG3153, Predicted acetyltransferase [General function prediction only]; pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. nadC: nicotinate-nucleotide pyrophosphor; putative acetyltransferase 342899 5173095 CMM_0281 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221021.1 342105 R 443906 CDS YP_001221022.1 148271461 5173346 complement(342905..345463) 1 NC_009480.1 conserved hypothetical protein (ZP_00294435.1| hypothetical protein Tfus02000641 [Thermobifida fusca]; NP_624665.1| putative large secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 345463 5173346 CMM_0282 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221022.1 342905 R 443906 CDS YP_001221023.1 148271462 5173646 345561..346151 1 NC_009480.1 putative adenylate kinase (NP_599567.1| putative adenylate kinase [Corynebacterium glutamicum ATCC 13032]; NP_293926.1| hypothetical protein [Deinococcus radiodurans R1]).; Function unclear; putative adenylate kinase 346151 5173646 CMM_0283 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative adenylate kinase YP_001221023.1 345561 D 443906 CDS YP_001221024.1 148271463 5173552 complement(346118..346705) 1 NC_009480.1 hypothetical protein 346705 5173552 CMM_0284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221024.1 346118 R 443906 CDS YP_001221025.1 148271464 5173929 complement(346723..347499) 1 NC_009480.1 putative permease, DMT family (ZP_00198666.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Kineococcus radiotolerans SRS30216]; NP_629665.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00892, DUF6,Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function.; Specificity unclear; permease DMT family 347499 5173929 CMM_0285 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease DMT family YP_001221025.1 346723 R 443906 CDS YP_001221026.1 148271465 5175394 347748..348374 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_629666.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_940577.1| Putative TetR-family transcriptional regulator [Corynebacterium diphtheriae]). InterPro: Bacterial regulatory proteins TetR family; Specificity unclear; TetR family transcriptional regulator 348374 5175394 CMM_0286 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221026.1 347748 D 443906 CDS YP_001221027.1 148271466 5173476 348371..348868 1 NC_009480.1 putative diadenosine tetraphosphate (Ap4A) hydrolase, Hit family (NP_539734.1| BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMETRICAL) [Brucella melitensis]; NP_102422.1| probable Hit-like protein involved in cell-cycle regulation [Mesorhizobium loti MAFF303099]). cd01277, HINT_subgroup, HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides.; Specificity unclear; diadenosine tetraphosphate hydrolase 348868 5173476 CMM_0287 Clavibacter michiganensis subsp. michiganensis NCPPB 382 diadenosine tetraphosphate hydrolase YP_001221027.1 348371 D 443906 CDS YP_001221028.1 148271467 5174709 348940..349608 1 NC_009480.1 putative oxidoreductase/dehydrogenase (NP_823521.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; CAC14507.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative oxidoreductase 349608 5174709 CMM_0288 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221028.1 348940 D 443906 CDS YP_001221029.1 148271468 5173491 complement(349694..350386) 1 NC_009480.1 conserved secreted protein (ZP_00227777.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_939578.1| Putative secreted protein [Corynebacterium diphtheriae]). pfam04264, YceI,YceI like family. E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised.; Conserved hypothetical protein; hypothetical protein 350386 5173491 CMM_0289 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221029.1 349694 R 443906 CDS YP_001221030.1 148271469 5173374 350578..351084 1 NC_009480.1 RNA polymerase sigma factor, ECF-subfamily (NP_215249.1| sigL [Mycobacterium tuberculosis H37Rv]; ZP_00225475.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]). pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. pfam04545, Sigma70_r4, Sigma-70,region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; RNA polymerase ECF-subfamily sigma factor 351084 sigL 5173374 sigL Clavibacter michiganensis subsp. michiganensis NCPPB 382 RNA polymerase ECF-subfamily sigma factor YP_001221030.1 350578 D 443906 CDS YP_001221031.1 148271470 5175170 351081..351872 1 NC_009480.1 conserved membrane protein, putative anti-sigma factor (NP_215250.1| hypothetical protein Rv0736 [Mycobacterium tuberculosis H37Rv]; NP_826301.1| putative membrane protein [Streptomyces avermitilis MA-4680]). similarity to anti-sigma factors (COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]); Conserved hypothetical protein; hypothetical protein 351872 5175170 CMM_0291 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221031.1 351081 D 443906 CDS YP_001221032.1 148271471 5173750 complement(352171..352761) 1 NC_009480.1 hypothetical protein (ZP_00410568.1| hypothetical protein ArthDRAFT_3888 [Arthrobacter sp. FB24]).; hypothetical protein 352761 5173750 CMM_0292 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221032.1 352171 R 443906 CDS YP_001221033.1 148271472 5173707 352835..354202 1 NC_009480.1 putative MFS permease (ZP_00098466.1| COG0477: Permeases of the major facilitator superfamily [Desulfitobacterium hafniense]; NP_834739.1| Macrolide-efflux protein [Bacillus cereus ATCC 14579]). pfam05977,DUF894, Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins.; Specificity unclear; putative MFS permease 354202 5173707 CMM_0293 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221033.1 352835 D 443906 CDS YP_001221034.1 148271473 5174184 complement(354199..354702) 1 NC_009480.1 conserved hypothetical protein (NP_294991.1| hypothetical protein [Deinococcus radiodurans R1]; NP_827164.1| hypothetical protein SAV5987 [Streptomyces avermitilis MA-4680]). PPR: pentatricopeptide repeat domain; Family membership; hypothetical protein 354702 5174184 CMM_0294 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221034.1 354199 R 443906 CDS YP_001221035.1 148271474 5174309 complement(354731..355741) 1 NC_009480.1 HTH-type transcriptional repressor, LacI family (NP_823290.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00330608.1| COG1609: Transcriptional regulators [Moorella thermoacetica ATCC 39073]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; LacI family transcriptional regulator 355741 5174309 CMM_0295 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001221035.1 354731 R 443906 CDS YP_001221036.1 148271475 5175511 355969..357261 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (ZP_00121433.1| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]; NP_826156.1| putative sugar transporter solute-binding protein [Streptomyces avermitilis MA-4680]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 357261 5175511 CMM_0296 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001221036.1 355969 D 443906 CDS YP_001221037.1 148271476 5175586 357272..358297 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_826157.1| putative binding protein-dependent transporter [Streptomyces avermitilis MA-4680]; NP_533738.1| ABC transporter, membrane spanning protein [sugar] [Agrobacterium tumefaciens str. C58]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 358297 5175586 CMM_0297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221037.1 357272 D 443906 CDS YP_001221038.1 148271477 5173955 358294..359199 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_826158.1| putative binding protein-dependent transporter [Streptomyces avermitilis MA-4680]; NP_533737.1| ABC transporter, membrane spanning protein [sugar] [Agrobacterium tumefaciens str. C58]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative sugar ABC transporter, permease component 359199 5173955 CMM_0298 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221038.1 358294 D 443906 CDS YP_001221039.1 148271478 5174387 359196..361577 1 NC_009480.1 putative beta-glycosidase, putative xylosidase (ZP_00226641.1| COG1472: Beta-glucosidase-related glycosidases [Kineococcus radiotolerans SRS30216]; JC7728 xylan 1,4-beta-xylosidase (EC 3.2.1.37) - Streptomyces thermoviolaceus). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.; Specificity unclear; putative beta-glycosidase 361577 bglX 5174387 bglX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glycosidase YP_001221039.1 359196 D 443906 CDS YP_001221040.1 148271479 5173104 complement(361717..362565) 1 NC_009480.1 putative nucleoside-diphosphate-sugar epimerase (ZP_00227284.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_822058.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate-sugar epimerase 362565 5173104 CMM_0300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001221040.1 361717 R 443906 CDS YP_001221041.1 148271480 5174376 362661..363410 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_822057.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; CAE53340.1| putative TetR-family transcitpional regulator [Actinoplanes teichomyceticus]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 363410 5174376 CMM_0301 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221041.1 362661 D 443906 CDS YP_001221042.1 148271481 5174425 complement(363450..364307) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (NP_625190.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]; NP_821830.1| putative DNA-binding protein [Streptomyces avermitilis MA-4680]). pfam01381,HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Function unclear; Cro/CI family transcriptional regulator 364307 5174425 CMM_0302 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001221042.1 363450 R 443906 CDS YP_001221043.1 148271482 5174560 364409..365089 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (ZP_00227716.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_625189.1| putative short chain oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain oxidoreductase 365089 5174560 CMM_0303 Clavibacter michiganensis subsp. michiganensis NCPPB 382 short chain oxidoreductase YP_001221043.1 364409 D 443906 CDS YP_001221044.1 148271483 5174585 365157..365555 1 NC_009480.1 conserved hypothetical protein (NP_386041.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]; NP_739257.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam05146, DUF704,Aha1 domain. The function of this presumed domain is unknown.; hypothetical protein 365555 5174585 CMM_0304 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221044.1 365157 D 443906 CDS YP_001221045.1 148271484 5173130 365594..366160 1 NC_009480.1 putative acetyltransferase (ZP_00227803.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; NP_600641.1| acetyltransferase [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 366160 5173130 CMM_0305 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221045.1 365594 D 443906 CDS YP_001221046.1 148271485 5175434 366519..367412 1 NC_009480.1 Region start changed from 366300 to 366519 (-219 bases); hypothetical protein 367412 5175434 CMM_0306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221046.1 366519 D 443906 CDS YP_001221047.1 148271486 5174749 complement(367435..367848) 1 NC_009480.1 putative thiosulfate sulfurtransferase (ZP_00227801.1| COG0607: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]; NP_625584.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). Catalyzes although with low efficiency the sulfur transfer reaction from thiosulfate to cyanide (By similarity). pfam00581,Rhodanese, Rhodanese-like domain. InterPro: Rhodanese/cdc25 fold; Function unclear; putative sulfurtransferase 367848 5174749 CMM_0307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sulfurtransferase YP_001221047.1 367435 R 443906 CDS YP_001221048.1 148271487 5175081 368106..369347 1 NC_009480.1 conserved hypothetical protein (BAB98631.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]; NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]).; hypothetical protein 369347 5175081 CMM_0308 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221048.1 368106 D 443906 CDS YP_001221049.1 148271488 5175182 complement(369387..369920) 1 NC_009480.1 conserved hypothetical protein (NP_627216.1| hypothetical protein SCE50.21 [Streptomyces coelicolor A3(2)]; ZP_00191774.2| COG0529: Adenylylsulfate kinase and related kinases [Kineococcus radiotolerans SRS30216]). weak similarity to: smart00382, AAA, ATPases associated with a variety of cellular activities; hypothetical protein 369920 5175182 CMM_0309 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221049.1 369387 R 443906 CDS YP_001221050.1 148271489 5175061 370093..371634 1 NC_009480.1 alpha-L-arabinofuranosidase (Arabinosidase) (ZP_00121523.2| COG3534: Alpha-L-arabinofuranosidase [Bifidobacterium longum DJO10A]; NP_626674.1| alpha-L-arabinofuranosidase [Streptomyces coelicolor A3(2)]). ,pfam03662, Glyco_hydro_79n, Glycosyl hydrolase family 79,N-terminal domain. , pfam06964, Alpha-L-AF_C, Alpha-L-arabinofuranosidase C-terminus.This catalyses the hydrolysis of nonreducing terminal alpha-L-arabinofuranosidic linkages in L-arabinose-containing polysaccharides.; High confidence in function and specificity; hypothetical protein 371634 abfA1 5175061 abfA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221050.1 370093 D 443906 CDS YP_001221051.1 148271490 5175955 complement(371722..371940) 1 NC_009480.1 hypothetical protein (NP_626168.1| hypothetical hydrophilic protein [Streptomyces coelicolor A3(2)]; NP_845828.1| conserved hypothetical protein [Bacillus anthracis str. Ames]).; hypothetical protein 371940 5175955 CMM_0311 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221051.1 371722 R 443906 CDS YP_001221052.1 148271491 5175571 complement(372277..372867) 1 NC_009480.1 putative acetyltransferase (ZP_00184424.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Exiguobacterium sp. 255-15]; NP_626962.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 372867 5175571 CMM_0312 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221052.1 372277 R 443906 CDS YP_001221053.1 148271492 5175024 complement(372914..373255) 1 NC_009480.1 hypothetical protein (NP_825872.1| putative Lsr2-like protein [Streptomyces avermitilis MA-4680]; ZP_00293146.1| hypothetical protein Tfus02001333 [Thermobifida fusca]).; hypothetical protein 373255 5175024 CMM_0313 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221053.1 372914 R 443906 CDS YP_001221054.1 148271493 5174025 373355..374428 1 NC_009480.1 conserved hypothetical protein, putative GTPase (NP_962706.1| hypothetical protein MAP3772c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00173773.1| COG0523: Putative GTPases (G3E family) [Methylobacillus flagellatus KT]). pfam02492, cobW, Cobalamin synthesis protein/P47K.; hypothetical protein 374428 5174025 CMM_0314 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221054.1 373355 D 443906 CDS YP_001221055.1 148271494 5174473 374511..375521 1 NC_009480.1 putative thioredoxin reductase (ZP_00217649.1| COG0492: Thioredoxin reductase [Burkholderia cepacia R18194]; NP_639620.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function unclear; putative thioredoxin reductase 375521 5174473 CMM_0315 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin reductase YP_001221055.1 374511 D 443906 CDS YP_001221056.1 148271495 5174291 375588..377780 1 NC_009480.1 putative ATP-dependant protease, ATPase subunit (ZP_00225929.1| COG0542: ATPases with chaperone activity,ATP-binding subunit [Kineococcus radiotolerans SRS30216]; YP_056693.1| ATP-dependent protease (Clp chaperone) [Propionibacterium acnes KPA171202]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA) (twice). clpX: ATP-dependent Clp protease ATP; Function unclear; ATPase with chaperone activity, ATP-binding subunit 377780 clpY 5174291 clpY Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATPase with chaperone activity, ATP-binding subunit YP_001221056.1 375588 D 443906 CDS YP_001221057.1 148271496 5175612 complement(377847..380030) 1 NC_009480.1 alpha-galactosidase (Melibiase)(ZP_00226650.1| COG3345: Alpha-galactosidase [Kineococcus radiotolerans SRS30216]; AAD30994.2| alpha-galactosidase [Bifidobacterium adolescentis]). pfam02065, Melibiase,Melibiase.; High confidence in function and specificity; hypothetical protein 380030 agaA 5175612 agaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221057.1 377847 R 443906 CDS YP_001221058.1 148271497 5173131 380141..380620 1 NC_009480.1 putative transcriptional regulator (only weak similarity, ZP_00199538.1| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_624573.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]).; Family membership; putative transcriptional regulator 380620 5173131 CMM_0318 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001221058.1 380141 D 443906 CDS YP_001221059.1 148271498 5175308 complement(380682..381347) 1 NC_009480.1 conserved hypothetical protein (ZP_00199464.2| hypothetical protein Krad06000208 [Kineococcus radiotolerans SRS30216]; NP_216552.1| hypothetical protein Rv2036 [Mycobacterium tuberculosis H37Rv]; NP_630338.1| conserved hypothetical protein SCAH10.03 [Streptomyces coelicolor A3(2)]).; hypothetical protein 381347 5175308 CMM_0319 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221059.1 380682 R 443906 CDS YP_001221060.1 148271499 5172964 complement(381414..381764) 1 NC_009480.1 hypothetical protein 381764 5172964 CMM_0320 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221060.1 381414 R 443906 CDS YP_001221061.1 148271500 5174716 381880..382884 1 NC_009480.1 putative oxidoreductase (ZP_00225711.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00292358.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Thermobifida fusca]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 382884 5174716 CMM_0321 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221061.1 381880 D 443906 CDS YP_001221062.1 148271501 5173144 382892..384100 1 NC_009480.1 putative dipeptidase (NP_826200.1| putative dipeptidase [Streptomyces avermitilis MA-4680]; ZP_00191103.2| COG2355: Zn-dependent dipeptidase,microsomal dipeptidase homolog [Kineococcus radiotolerans SRS30216]). pfam01244, Renal_dipeptase, Renal dipeptidase.; High confidence in function and specificity; putative dipeptidase 384100 5173144 CMM_0322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dipeptidase YP_001221062.1 382892 D 443906 CDS YP_001221063.1 148271502 5173115 384097..384960 1 NC_009480.1 putative acetyltransferase, GnaT family (NP_629283.1| hypothetical protein [Streptomyces coelicolor A3(2)]; AAB84468.1| putative acetyl transferase [Bacillus subtilis]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; GNAT family acetyltransferase 384960 5173115 CMM_0323 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GNAT family acetyltransferase YP_001221063.1 384097 D 443906 CDS YP_001221064.1 148271503 5174983 complement(384894..386636) 1 NC_009480.1 putative ABC transporter (fused permease/ATPase) (NP_631729.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; AAN77618.1| putative ABC transporter [Mycobacterium avium subsp. paratuberculosis]). putative exporter of siderophore/antibiotic.; High confidence in function and specificity; putative ABC transporter (fused permease/ATPase) 386636 5174983 CMM_0324 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter (fused permease/ATPase) YP_001221064.1 384894 R 443906 CDS YP_001221065.1 148271504 5172932 complement(386636..388456) 1 NC_009480.1 putative ABC transporter (fused permease/ATPase) (NP_631728.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00267801.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Rhodospirillum rubrum]). putative exporter of siderophore/antibiotic.; High confidence in function and specificity; putative ABC transporter (fused permease/ATPase) 388456 5172932 CMM_0325 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter (fused permease/ATPase) YP_001221065.1 386636 R 443906 CDS YP_001221066.1 148271505 5174014 complement(388453..389223) 1 NC_009480.1 putative methyltransferase (NP_631727.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_962672.1| hypothetical protein MAP3738c [Mycobacterium avium subsp. paratuberculosis str. k10]). PUTATIVELY INVOLVED IN METHYLATION OF SIDEROPHORE/ANTIBIOTIC.; Specificity unclear; hypothetical protein 389223 5174014 CMM_0326 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221066.1 388453 R 443906 CDS YP_001221067.1 148271506 5174437 complement(389220..390032) 1 NC_009480.1 putative thioesterase (NP_821582.1| putative thioesterase [Streptomyces avermitilis MA-4680]; S49055 thioesterase - Streptomyces fradiae (strain T59235)). pfam00975, Thioesterase, Thioesterase domain. Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to the type II fatty acid thioesterases of vertebrates.; High confidence in function and specificity; putative thioesterase 390032 5174437 CMM_0327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioesterase YP_001221067.1 389220 R 443906 CDS YP_001221068.1 148271507 5173269 complement(390130..392058) 1 NC_009480.1 putative oxidoreductase/methylase (NP_631724.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_404400.1| conserved hypothetical protein [Yersinia pestis]; NP_631727.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). two domains: N-terminal (COG4693, PchG, Oxidoreductase (NAD-binding),involved in siderophore biosynthesis; pfam07414, YbtU,Yersiniabactin synthetase thiazolinyl reductase component YbtU. This family represents the thiazolinyl reductase component YbtU (approximately 350 residues long) of the bacterial four-protein yersiniabactin synthetase complex.). C-terminal putative methylase(COG2242, CobL,Precorrin-6B methylase 2,COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis; pfam00891,Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilise S-adenosyl methionine.). putatively involved in the modification of a siderophore/antibiotic.; Specificity unclear; putative oxidoreductase/methylase 392058 5173269 CMM_0328 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase/methylase YP_001221068.1 390130 R 443906 CDS YP_001221069.1 148271508 5174419 complement(392055..393200) 1 NC_009480.1 putative dehydrogenase, iron-regulated protein (NP_631723.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_962677.1| hypothetical protein MAP3743 [Mycobacterium avium subsp. paratuberculosis str. k10]). putatively involved in the modification of a siderophore/antibiotic. weak similarity to: COG1748, LYS9,Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; pfam03435, Saccharop_dh,Saccharopine dehydrogenase.; Function unclear; putative dehydrogenase, iron-regulated protein 393200 5174419 CMM_0329 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase, iron-regulated protein YP_001221069.1 392055 R 443906 CDS YP_001221070.1 148271509 5175282 complement(393197..398776) 1 NC_009480.1 non-ribosomal peptide syntethase (NP_631722.1| putative non-ribosomal peptide synthase [Streptomyces coelicolor A3(2)]; NP_252915.1| pyochelin synthetase [Pseudomonas aeruginosa PA01]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. pfam00668, Condensation, Condensation domain. pfam00501,AMP-binding, AMP-binding enzyme. pfam01209,Ubie_methyltran, ubiE/COQ5 methyltransferase family. pfam00550, PP-binding, Phosphopantetheine attachment site. pfam00975, Thioesterase, Thioesterase domain.; Specificity unclear; non-ribosomal peptide synthetase 398776 npsB 5175282 npsB Clavibacter michiganensis subsp. michiganensis NCPPB 382 non-ribosomal peptide synthetase YP_001221070.1 393197 R 443906 CDS YP_001221071.1 148271510 5174409 complement(398773..405660) 1 NC_009480.1 non ribosomal peptide synthethase (NP_631721.1| putative non-ribosomal peptide synthase [Streptomyces coelicolor A3(2)]; NP_534178.1| non-ribosomal peptide synthetase [Agrobacterium tumefaciens str. C58]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. two activation/conjugation domains. pfam00501, AMP-binding, AMP-binding enzyme (twice: Aa 609-1014, 1682-2079). pfam00668, Condensation,Condensation domain (twice: Aa 112-409, 1185-1475). pfam00550, PP-binding, Phosphopantetheine attachment site (thrice: Aa 13-76, 1099-1162, 2188-2246).; Specificity unclear; non-ribosomal peptide synthetase 405660 npsA 5174409 npsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 non-ribosomal peptide synthetase YP_001221071.1 398773 R 443906 CDS YP_001221072.1 148271511 5174131 405761..407479 1 NC_009480.1 putative organic acid CoA ligase (NP_631720.1| putative AMP-binding ligase [Streptomyces coelicolor A3(2)]; ZP_00059514.1| COG1021: Peptide arylation enzymes [Thermobifida fusca]). putatively involved in the biosynthesis of a catecholate siderophore/antibiotic. pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; hypothetical protein 407479 5174131 CMM_0332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221072.1 405761 D 443906 CDS YP_001221073.1 148271512 5173961 407472..408191 1 NC_009480.1 putative 4-phosphopantetheinyl transferase (NP_337369.1| EntD-related protein [Mycobacterium tuberculosis CDC1551]; AAR92400.1| Sfp-type phosphopantetheinyl transferase [Saccharopolyspora erythraea]). pfam01648, ACPS, 4'-phosphopantetheinyl transferase superfamily.; Specificity unclear; 4-phosphopantetheinyl transferase 408191 5173961 CMM_0333 Clavibacter michiganensis subsp. michiganensis NCPPB 382 4-phosphopantetheinyl transferase YP_001221073.1 407472 D 443906 CDS YP_001221074.1 148271513 5175569 408202..409668 1 NC_009480.1 putative anthranilate synthase (CAG20074.1| hypotetical anthranilate synthase [Photobacterium profundum]; NP_405477.1| putative salicylate synthetase [Yersinia pestis]). putatively involved in the synthesis of an aromatic acid (salicylate, isochorismate) for a catecholate siderophore/antibiotic. pfam00425,Chorismate_bind, chorismate binding enzyme. This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase,aminodeoxychorismate synthase and para-aminobenzoate synthase.; Specificity unclear; putative organic acid synthase 409668 5175569 CMM_0334 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative organic acid synthase YP_001221074.1 408202 D 443906 CDS YP_001221075.1 148271514 5175129 complement(409681..411495) 1 NC_009480.1 conserved membrane protein (NP_531343.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; NP_384960.1| HYPOTHETICAL TRANSMEMBRANE SIGNAL PEPTIDE PROTEIN [Sinorhizobium meliloti 1021]).; hypothetical protein 411495 5175129 CMM_0335 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221075.1 409681 R 443906 CDS YP_001221076.1 148271515 5175397 complement(411488..411898) 1 NC_009480.1 hypothetical protein 411898 5175397 CMM_0336 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221076.1 411488 R 443906 CDS YP_001221077.1 148271516 5174341 complement(411935..413278) 1 NC_009480.1 conserved hypothetical protein, putative peptidase (AAP13501.1| Orf12 [Streptomyces clavuligerus]; NP_959400.1| LpqF [Mycobacterium avium subsp. paratuberculosis str. k10]). , weak similarities to: pfam00768, Peptidase_S11, D-alanyl-D-alanine carboxypeptidase.; Function unclear; hypothetical protein 413278 5174341 CMM_0337 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221077.1 411935 R 443906 CDS YP_001221078.1 148271517 5175962 complement(413447..414691) 1 NC_009480.1 conserved hypothetical protein (maybe involved in cell wall metabolism; putative N-acetylmuramoyl-l-alanine amidase) (ZP_00235910.1| putative peptidoglycan binding domain protein [Bacillus cereus G9241]; NP_733648.1| hypothetical protein [Streptomyces coelicolor A3(2)]). pfam01471, PG_binding_1, Putative peptidoglycan binding domain.; Function unclear; hypothetical protein 414691 5175962 CMM_0338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221078.1 413447 R 443906 CDS YP_001221079.1 148271518 5175786 complement(414897..415358) 1 NC_009480.1 conserved membrane protein (NP_827521.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; NP_938697.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam07332,DUF1469, Protein of unknown function (DUF1469). This family consists of several hypothetical bacterial proteins of around 140 residues in length. Members of the family seem to be found exclusively in Actinomycetes. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein 415358 5175786 CMM_0339 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221079.1 414897 R 443906 CDS YP_001221080.1 148271519 5175902 complement(415448..416053) 1 NC_009480.1 Hypothetical protein; hypothetical protein 416053 5175902 CMM_0340 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221080.1 415448 R 443906 CDS YP_001221081.1 148271520 5175911 complement(416050..416628) 1 NC_009480.1 Hypothetical protein; hypothetical protein 416628 5175911 CMM_0341 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221081.1 416050 R 443906 CDS YP_001221082.1 148271521 5175797 complement(416625..416999) 1 NC_009480.1 hypothetical protein 416999 5175797 CMM_0342 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221082.1 416625 R 443906 CDS YP_001221083.1 148271522 5175374 complement(417181..417618) 1 NC_009480.1 conserved hypothetical protein, putative alkaline shock protein (ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_827606.1| hypothetical protein SAV6430 [Streptomyces avermitilis MA-4680]). pfam03780, DUF322,Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response. flhB_rel: FlhB domain protein; putative alkaline shock protein 417618 5175374 CMM_0343 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alkaline shock protein YP_001221083.1 417181 R 443906 CDS YP_001221084.1 148271523 5175819 complement(417819..419000) 1 NC_009480.1 putative transcriptional regulator, AraC family (ZP_00024251.1| COG2207: AraC-type DNA-binding domain-containing proteins [Ralstonia metallidurans]; NP_962164.1| hypothetical protein MAP3230c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00165,HTH_AraC, Bacterial regulatory helix-turn-helix proteins,araC family. Members of this family contain two structural repeats of this domain.; High confidence in function and specificity; AraC family transcriptional regulator 419000 5175819 CMM_0344 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AraC family transcriptional regulator YP_001221084.1 417819 R 443906 CDS YP_001221085.1 148271524 5175732 complement(419162..420103) 1 NC_009480.1 conserved exported protein, putative dessication-related protein (ZP_00227307.1| hypothetical protein Krad06001366 [Kineococcus radiotolerans SRS30216]; ZP_00280800.1| hypothetical protein Bcep02004480 [Burkholderia fungorum LB400]).; Conserved hypothetical protein; hypothetical protein 420103 5175732 CMM_0345 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221085.1 419162 R 443906 CDS YP_001221086.1 148271525 5175646 complement(420329..420871) 1 NC_009480.1 conserved membrane protein (ZP_00227499.1| COG1121: ABC-type Mn/Zn transport systems, ATPase component [Kineococcus radiotolerans SRS30216]; NP_821494.1| hypothetical protein SAV320 [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 420871 5175646 CMM_0346 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221086.1 420329 R 443906 CDS YP_001221087.1 148271526 5173259 complement(421093..424278) 1 NC_009480.1 putative alpha-mannosidase (NP_822929.1| putative alpha-mannosidase [Streptomyces avermitilis MA-4680]; YP_054780.1| glycosyl hydrolase [Propionibacterium acnes KPA171202]). pfam01074, Glyco_hydro_38, Glycosyl hydrolases family 38.; High confidence in function and specificity; putative alpha-mannosidase 424278 manX 5173259 manX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-mannosidase YP_001221087.1 421093 R 443906 CDS YP_001221088.1 148271527 5173178 complement(424342..425685) 1 NC_009480.1 putative 6-phospho-beta-glucosidase (NP_822930.1| putative 6-phospho-beta-glucosidase [Streptomyces avermitilis MA-4680]; YP_054779.1| putative glucosidase [Propionibacterium acnes KPA171202]). pfam02056,Glyco_hydro_4, Family 4 glycosyl hydrolase.; High confidence in function and specificity; putative 6-phospho-beta-glucosidase 425685 bglY 5173178 bglY Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 6-phospho-beta-glucosidase YP_001221088.1 424342 R 443906 CDS YP_001221089.1 148271528 5173644 complement(425682..426407) 1 NC_009480.1 putative transcriptional regulator, DeoR family (NP_822931.1| putative DeoR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_624108.1| Transcriptional regulator of sugar metabolism [Thermoanaerobacter tengcongensis]). pfam00455, DeoR,Bacterial regulatory proteins, deoR family. InterPro: Bacterial regulatory protein DeoR family; Specificity unclear; DeoR family transcriptional regulator 426407 5173644 CMM_0349 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DeoR family transcriptional regulator YP_001221089.1 425682 R 443906 CDS YP_001221090.1 148271529 5174916 426635..427657 1 NC_009480.1 putative carbohydrate kinase (NP_822932.1| putative carbohydrate kinase [Streptomyces avermitilis MA-4680]; ZP_00226288.1| COG0524: Sugar kinases, ribokinase family [Kineococcus radiotolerans SRS30216]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative carbohydrate kinase 427657 5174916 CMM_0350 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carbohydrate kinase YP_001221090.1 426635 D 443906 CDS YP_001221091.1 148271530 5175227 427733..429019 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (NP_822933.1| putative sugar binding secreted protein [Streptomyces avermitilis MA-4680]; YP_054776.1| sugar-binding protein [Propionibacterium acnes KPA171202]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate binding protein 429019 5175227 CMM_0351 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001221091.1 427733 D 443906 CDS YP_001221092.1 148271531 5175079 429016..430014 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_822934.1| putative sugar transport system permease [Streptomyces avermitilis MA-4680]; YP_054775.1| transport permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter, permease component 430014 5175079 CMM_0352 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221092.1 429016 D 443906 CDS YP_001221093.1 148271532 5174914 430011..430934 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_822935.1| putative ABC-type transport system permease protein [Streptomyces avermitilis MA-4680]; YP_054774.1| sugar transport permease BglB [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative sugar ABC transporter, permease component 430934 5174914 CMM_0353 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221093.1 430011 D 443906 CDS YP_001221094.1 148271533 5174911 430931..431695 1 NC_009480.1 putative glucosamine-6-phosphate deaminase (Glucosamine-6- phosphate isomerase) (Q9K487|NAGB_STRCO Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate isomerase) (GNPDA) (GlcN6P deaminase); ZP_00120662.1| COG0363: 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Bifidobacterium longum DJO10A]). Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity). pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase. nagB: glucosamine-6-phosphate isomerase; High confidence in function and specificity; putative glucosamine-6-phosphate isomerase 431695 nagB 5174911 nagB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucosamine-6-phosphate isomerase YP_001221094.1 430931 D 443906 CDS YP_001221095.1 148271534 5175575 431769..434759 1 NC_009480.1 beta-galactosidase (Lactase) (AAQ19029.1| beta-galactosidase [Arthrobacter sp. SB]; ZP_00226654.1| COG3250: Beta-galactosidase/ beta-glucuronidase [Kineococcus radiotolerans SRS30216]). pfam02837,Glyco_hydro_2_N, Glycosyl hydrolases family 2, sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. pfam02929,Bgal_small_N, Beta galactosidase small chain, N terminal domain. sipfam02930, Bgal_small_C, Beta galactosidase small chain, C terminal domain. This domain is found in the carboxy-terminal portion of the small chain of dimeric beta-galactosidases EC:3.2.1.23. This domain is also found in single chain beta-galactosidase.; High confidence in function and specificity; beta-galactosidase 434759 bgaA 5175575 bgaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-galactosidase YP_001221095.1 431769 D 443906 CDS YP_001221096.1 148271535 5173221 complement(434829..435344) 1 NC_009480.1 putative acyl-CoA thioesterase (NP_967633.1| conserved hypothetical protein [Bdellovibrio bacteriovorus HD100]; ZP_00269440.1| hypothetical protein Rrub02001636 [Rhodospirillum rubrum]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes, principally thioesterases. InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site; Specificity unclear; putative acyl-CoA thioesterase 435344 5173221 CMM_0356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA thioesterase YP_001221096.1 434829 R 443906 CDS YP_001221097.1 148271536 5174509 435599..436171 1 NC_009480.1 putative NADPH-dependent FMN reductase (NP_102215.1| hypothetical protein mlr0414 [Mesorhizobium loti MAFF303099]; CAD47912.1| putative NADPH:quinone oxidoreductase [Arthrobacter nicotinovorans]). pfam03358,FMN_red, NADPH-dependent FMN reductase.; Function unclear; hypothetical protein 436171 5174509 CMM_0357 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221097.1 435599 D 443906 CDS YP_001221098.1 148271537 5174143 436334..437383 1 NC_009480.1 putative transcriptional regulator, LacI family (NP_629820.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00227762.1| COG1609: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; LacI family transcriptional regulator 437383 5174143 CMM_0358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001221098.1 436334 D 443906 CDS YP_001221099.1 148271538 5174268 437577..438791 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (ZP_00192200.3| COG1653: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_625350.1| putative sugar transport sugar binding protein [Streptomyces coelicolor A3(2)]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 438791 5174268 CMM_0359 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001221099.1 437577 D 443906 CDS YP_001221100.1 148271539 5174165 438788..439747 1 NC_009480.1 putative sugar ABC trasnporter, permease component (NP_625351.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226127.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 439747 5174165 CMM_0360 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221100.1 438788 D 443906 CDS YP_001221101.1 148271540 5174362 439744..440574 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_625352.1| putative sugar transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226128.1| COG0395: ABC-type sugar transport system, permease component [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 440574 5174362 CMM_0361 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221101.1 439744 D 443906 CDS YP_001221102.1 148271541 5173839 440654..442702 1 NC_009480.1 putative alpha glucosidase (NP_459046.1| putative glycosyl hydrolase [Salmonella typhimurium LT2]; XP_388973.1| hypothetical protein FG08797.1 [Gibberella zeae PH-1])., pfam01055, Glyco_hydro_31, Glycosyl hydrolases family 31., InterPro: Glycoside hydrolase family 31; Specificity unclear; putative alpha glucosidase 442702 5173839 CMM_0362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha glucosidase YP_001221102.1 440654 D 443906 CDS YP_001221103.1 148271542 5173720 442816..443871 1 NC_009480.1 putative Fe3+-hydroxamate ABC transporter,substrate binding protein (ZP_00226720.1| COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_699933.1| iron compound ABC transporter, periplasmic iron compound-binding protein [Brucella suis 1330]). pfam01497, Peripla_BP_2, Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative Fe3+-hydroxamate ABC transporter,substrate binding protein 443871 5173720 CMM_0363 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-hydroxamate ABC transporter,substrate binding protein YP_001221103.1 442816 D 443906 CDS YP_001221104.1 148271543 5175935 443868..444944 1 NC_009480.1 putative Fe3+-siderophore ABC transporter, permease component (ZP_00226721.1| COG0609: ABC-type Fe3+-siderophore transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_793040.1| iron ABC transporter, permease protein, putative [Pseudomonas syringae pv. tomato str. DC3000]). pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family.; Specificity unclear; putative Fe3+-siderophore ABC transporter,permease component 444944 5175935 CMM_0364 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,permease component YP_001221104.1 443868 D 443906 CDS YP_001221105.1 148271544 5174524 444941..445711 1 NC_009480.1 putative Fe3+-siderophore ABC transporter, ATPase component (ZP_00226722.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Kineococcus radiotolerans SRS30216]; CAB92552.1| FecE protein [Serratia sp. ATCC 39006]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative Fe3+-siderophore ABC transporter,ATPase component 445711 5174524 CMM_0365 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,ATPase component YP_001221105.1 444941 D 443906 CDS YP_001221106.1 148271545 5174286 445786..446586 1 NC_009480.1 putative nucleoside-diphosphate-sugar epimerase (ZP_00291479.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]; AAL17942.1| putative UDP glucose epimerase [Mycobacterium smegmatis]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor.; High confidence in function and specificity; putative nucleoside-diphosphate-sugar epimerase 446586 5174286 CMM_0366 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001221106.1 445786 D 443906 CDS YP_001221107.1 148271546 5174786 446742..447713 1 NC_009480.1 putative phosphonate ABC transporter, substrate-binding protein (ZP_00110175.1| COG3221: ABC-type phosphate/phosphonate transport system, periplasmic component [Nostoc punctiforme]; NP_946052.1| putative PhnD protein, phosphonate ABC transporter, periplasmic binding protein precursor [Rhodopseudomonas palustris CGA009]). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALKYLPHOSPHONATES. InterPro: Bacterial extracellular solute-binding proteins family 3; Specificity unclear; putative phosphonate ABC transporter, substrate-binding protein 447713 phnD 5174786 phnD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphonate ABC transporter, substrate-binding protein YP_001221107.1 446742 D 443906 CDS YP_001221108.1 148271547 5174242 447735..448634 1 NC_009480.1 putative phosphate/phosphonate ABC transporter,ATPase component (NP_243840.1| alkylphosphonate ABC tranporter (ATP-binding protein) [Bacillus halodurans]; NP_486270.1| ABC tranporter, ATP-binding component [Nostoc sp. PCC 7120]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative phosphate/phosphonate ABC transporter,ATPase component 448634 phnC 5174242 phnC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,ATPase component YP_001221108.1 447735 D 443906 CDS YP_001221109.1 148271548 5174303 448631..450379 1 NC_009480.1 putative phosphate/phosphonate ABC transporter,permease component (ZP_00203666.1| COG3639: ABC-type phosphate/phosphonate transport system, permease component [Dechloromonas aromatica RCB]; AAP27494.1| phosphonate ABC transporter, permease protein [Bacillus anthracis str. Ames]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component (twice). InterPro: Binding-protein-dependent transport systems inner membrane component; Specificity unclear; putative phosphate/phosphonate ABC transporter,permease component 450379 phnE 5174303 phnE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,permease component YP_001221109.1 448631 D 443906 CDS YP_001221110.1 148271549 5174351 450376..451269 1 NC_009480.1 putative 2-dehydropantoate 2-reductase (NP_337148.1| oxidoreductase, ketopantoate reductase family [Mycobacterium tuberculosis CDC1551]; Q9ABG6|PANE_CAUCR Putative 2-dehydropantoate 2-reductase (Ketopantoate reductase)). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. InterPro: Ketopantoate reductase ApbA/PanE. pfam02558, ApbA,Ketopantoate reductase PanE/ApbA. apbA_panE: 2-dehydropantoate 2-reductas; High confidence in function and specificity; 2-dehydropantoate 2-reductase 451269 panE 5174351 panE Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-dehydropantoate 2-reductase YP_001221110.1 450376 D 443906 CDS YP_001221111.1 148271550 5175413 complement(451286..451903) 1 NC_009480.1 putative acetyltransferase (NP_530883.1| acetyltransferase [Agrobacterium tumefaciens str. C58]; NP_437997.1| putative acetyltransferase protein [Sinorhizobium meliloti 1021]).; Function unclear; putative acetyltransferase 451903 phnX 5175413 phnX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221111.1 451286 R 443906 CDS YP_001221112.1 148271551 5173795 complement(451900..452610) 1 NC_009480.1 conserved hypothetical protein involved in phosphonate metabolism (NP_085695.1| ATP-binding component of phosphonate transport [Mesorhizobium loti MAFF303099]; AAL52063.1| PHOSPHONATES TRANSPORT ATP-BINDING PROTEIN PHNN [Brucella melitensis 16M]).; Function unclear; hypothetical protein 452610 phnN 5173795 phnN Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221112.1 451900 R 443906 CDS YP_001221113.1 148271552 5173815 complement(452607..453788) 1 NC_009480.1 putative metal-dependent hydrolase involved in phosphonate metabolism (ZP_00195547.1| COG3454: Metal-dependent hydrolase involved in phosphonate metabolism [Mesorhizobium sp. BNC1]; ZP_00124006.1| COG3454: Metal-dependent hydrolase involved in phosphonate metabolism [Pseudomonas syringae pv. syringae B728a]). BELONGS TO AN OPERON INVOLVED IN ALKYLPHOSPHONATE UPTAKE AND C-P LYASE. EXACT FUNCTION NOT KNOWN.; Function unclear; putative metal-dependent hydrolase involved in phosphonate metabolism 453788 phnM 5173815 phnM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal-dependent hydrolase involved in phosphonate metabolism YP_001221113.1 452607 R 443906 CDS YP_001221114.1 148271553 5174030 complement(453785..454531) 1 NC_009480.1 Conserved hypothetical protein possibly involved in phosphonate metabolism (ZP_00195546.1| hypothetical protein MBNC02000901 [Mesorhizobium sp. BNC1]; NP_697873.1| conserved hypothetical protein [Brucella suis 1330]). pfam06299, DUF1045, Protein of unknown function (DUF1045). This family consists of several hypothetical proteins from Agrobacterium, Rhizobium and Brucella species. The function of this family is unknown.; Function unclear; hypothetical protein 454531 phnV 5174030 phnV Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221114.1 453785 R 443906 CDS YP_001221115.1 148271554 5173843 complement(454528..455286) 1 NC_009480.1 putative phosphonate ABC transporter, ATPase (NP_104472.1| ATP-binding component of phosphonate transport, HisP-like nucleotide binding protein [Mesorhizobium loti MAFF303099]; NP_767866.1| phosphonate uptake transporter ATP-binding protein [Bradyrhizobium japonicum USDA 110]). PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALKYLPHOSPHONATES. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE TRANSPORT SYSTEM. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative phosphonate ABC transporter, ATPase 455286 phnL 5173843 phnL Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphonate ABC transporter, ATPase YP_001221115.1 454528 R 443906 CDS YP_001221116.1 148271555 5173987 complement(455283..456062) 1 NC_009480.1 putative phosphonate ABC transporter, ATPase (NP_530885.1| ABC transporter, nucleotide binding/ATPase protein [phosphonate] [Agrobacterium tumefaciens str. C58]; NP_437995.1| putative phosphonate uptake ABC transporter ATP-binding protein [Sinorhizobium meliloti 1021]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; phosphonate C-P lyase system protein PhnK 456062 phnK 5173987 phnK Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphonate C-P lyase system protein PhnK YP_001221116.1 455283 R 443906 CDS YP_001221117.1 148271556 5173970 complement(456059..456928) 1 NC_009480.1 putative C-P (carbon-phosphorus) lyase (NP_418522.1| phosphonate metabolism; conserved protein in phn operon [Escherichia coli K12]; NP_437994.1| putative C-P (carbon-phosphorus) lyase component protein [Sinorhizobium meliloti 1021]). pfam06007, PhnJ,Phosphonate metabolism protein PhnJ.; Specificity unclear; putative C-P (carbon-phosphorus) lyase 456928 phnJ 5173970 phnJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative C-P (carbon-phosphorus) lyase YP_001221117.1 456059 R 443906 CDS YP_001221118.1 148271557 5174086 complement(456925..458040) 1 NC_009480.1 conserved hypothetical protein involved in phosphonate metabolism (NP_104468.1| hypothetical protein,; ZP_00205860.1| COG3626: Uncharacterized enzyme of phosphonate metabolism [Pseudomonas syringae pv. syringae B728a]). pfam05861, PhnI, Bacterial phosphonate metabolism protein . Bacteria that use phosphonates as a phosphorus source must be able to break the stable carbon-phosphorus bond. In Escherichia coli phosphonates are broken down by a C-P lyase that has a broad substrate specificity. The genes for phosphonate uptake and degradation in E. coli are organised in an operon of 14 genes, named phnC to phnP. Three gene products (PhnC, PhnD and PhnE) comprise a binding protein-dependent phosphonate transporter, which also transports phosphate, phosphite, and certain phosphate esters such as phosphoserine; two gene products (PhnF and PhnO) may have a role in gene regulation; and nine gene products (PhnG, PhnH, PhnI, PhnJ, PhnK, PhnL,PhnM, PhnN, and PhnP) probably comprise a membrane-associated C-P lyase enzyme complex.; Function unclear; hypothetical protein 458040 phnI 5174086 phnI Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221118.1 456925 R 443906 CDS YP_001221119.1 148271558 5174151 complement(458040..458687) 1 NC_009480.1 putative C-P (carbon-phosphorus) lyase component (NP_104467.1| hypothetical protein, ; NP_946047.1| putative PhnH protein, phosphonate metabolism, function unknown [Rhodopseudomonas palustris CGA009]). pfam05845,PhnH, Bacterial phosphonate metabolism protein .; Function unclear; putative C-P (carbon-phosphorus) lyase component 458687 phnH 5174151 phnH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative C-P (carbon-phosphorus) lyase component YP_001221119.1 458040 R 443906 CDS YP_001221120.1 148271559 5174108 complement(458684..459175) 1 NC_009480.1 putative C-P (carbon-phosphorus lyase component (NP_530889.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; NP_437991.1| putative C-P (carbon-phosphorus lyase component protein [Sinorhizobium meliloti 1021]). pfam06754, PhnG,Phosphonate metabolism protein PhnG. The exact function of PhnG is unknown, however it is thought likely that along with six other proteins PhnG makes up the the C-P (carbon-phosphorus) lyase.; Function unclear; putative C-P (carbon-phosphorus lyase component 459175 phnG 5174108 phnG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative C-P (carbon-phosphorus lyase component YP_001221120.1 458684 R 443906 CDS YP_001221121.1 148271560 5174194 459383..460120 1 NC_009480.1 putative transcriptional regulator, GntR family (NP_530890.1| transcriptional regulator, GntR family [Agrobacterium tumefaciens str. C58 (U. Washington)]; NP_698105.1| transcriptional regulator, GntR family [Brucella suis 1330]). putative regulator of the phn operon. pfam00392, GntR, Bacterial regulatory proteins,gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator 460120 phnF 5174194 phnF Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001221121.1 459383 D 443906 CDS YP_001221122.1 148271561 5174320 460220..461437 1 NC_009480.1 putative multidrug efflux MFS permease (NP_737817.1| putative multidrug resistance protein [Corynebacterium efficiens YS-314]; NP_962079.1| hypothetical protein MAP3145c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative multidrug efflux MFS permease 461437 5174320 CMM_0382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug efflux MFS permease YP_001221122.1 460220 D 443906 CDS YP_001221123.1 148271562 5173232 461542..464274 1 NC_009480.1 phosphoenolpyruvate carboxylase (ZP_00293827.1| COG2352: Phosphoenolpyruvate carboxylase [Thermobifida fusca]; NP_695792.1| phosphoenolpyruvate carboxylase [Bifidobacterium longum NCC2705]). pfam00311, PEPcase,Phosphoenolpyruvate carboxylase.; High confidence in function and specificity; hypothetical protein 464274 ppcA 5173232 ppcA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221123.1 461542 D 443906 CDS YP_001221124.1 148271563 5173911 complement(464495..464998) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (NP_863201.1| hypothetical protein [Staphylococcus epidermidis ATCC 12228]; NP_900580.1| hypothetical protein CV0910 [Chromobacterium violaceum ATCC 12472]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 464998 5173911 CMM_0384 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001221124.1 464495 R 443906 CDS YP_001221125.1 148271564 5174963 complement(465146..466255) 1 NC_009480.1 putative L-threonine aldolase (NP_822663.1| putative L-threonine aldolase [Streptomyces avermitilis MA-4680]; YP_011095.1| threonine aldolase, low-specificity [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]). Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine L-threo-phenylserine L-beta-34- methylenedioxyphenylserine and L-beta-34-dihydroxyphenylserine.; High confidence in function and specificity; putative L-threonine aldolase 466255 ltaE 5174963 ltaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-threonine aldolase YP_001221125.1 465146 R 443906 CDS YP_001221126.1 148271565 5174566 complement(466292..466948) 1 NC_009480.1 putative NTP pyrophosphohydrolase (NP_624609.1| conserved hypothetical protein SCF85.08c [Streptomyces coelicolor A3(2)]; ZP_00229098.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Kineococcus radiotolerans SRS30216]). pfam00293,NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolase 466948 5174566 CMM_0386 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphohydrolase YP_001221126.1 466292 R 443906 CDS YP_001221127.1 148271566 5175772 complement(467019..468287) 1 NC_009480.1 putative sulfide:quinone oxidoreductase (NP_440916.1| hypothetical protein [Synechocystis sp. PCC 6803]; ZP_00084090.1| COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases [Pseudomonas fluorescens PfO-1]). , pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Function unclear; putative NAD(FAD)-dependent dehydrogenase 468287 5175772 CMM_0387 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD(FAD)-dependent dehydrogenase YP_001221127.1 467019 R 443906 CDS YP_001221128.1 148271567 5175098 468608..469054 1 NC_009480.1 putative stress-like protein (; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]). pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; Function unclear; putative alkaline shock protein 469054 5175098 CMM_0388 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alkaline shock protein YP_001221128.1 468608 D 443906 CDS YP_001221129.1 148271568 5175087 469277..470095 1 NC_009480.1 putative Aquaporin (ZP_00032143.1| COG0580: Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Burkholderia fungorum]; NP_884218.1| aquaporin Z [Bordetella parapertussis 12822]). Transport of water across the membrane. Possibly involved in the adaptation to variation in intravacuolar pH or osmolarity. MIP: MIP family channel proteins pfam00230, MIP, Major intrinsic protein. MIP (Major Intrinsic Protein) family proteins exhibit essentially two distinct types of channel properties: (1) specific water transport by the aquaporins, and (2) small neutral solutes transport, such as glycerol by the glycerol facilitators.; High confidence in function and specificity; hypothetical protein 470095 aqpZ 5175087 aqpZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221129.1 469277 D 443906 CDS YP_001221130.1 148271569 5175858 470190..471176 1 NC_009480.1 hypothetical protein (similarities of the N-terminal part to: ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 471176 5175858 CMM_0390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221130.1 470190 D 443906 CDS YP_001221131.1 148271570 5175051 complement(471212..471784) 1 NC_009480.1 hypothetical protein (ZP_00057389.1| hypothetical protein [Thermobifida fusca]; CAF19543.1| secreted protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 471784 5175051 CMM_0391 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221131.1 471212 R 443906 CDS YP_001221132.1 148271571 5175034 complement(471875..472327) 1 NC_009480.1 conserved hypothetical protein (ZP_00223109.1| COG3152: Predicted membrane protein [Burkholderia cepacia R1808]; NP_708910.1| putative cytochrome [Shigella flexneri 2a str. 301]). pfam05656, DUF805, Protein of unknown function (DUF805).; Function unclear; hypothetical protein 472327 5175034 CMM_0392 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221132.1 471875 R 443906 CDS YP_001221133.1 148271572 5174906 complement(472374..473138) 1 NC_009480.1 conserved hypothetical protein (NP_854517.1| HYPOTHETICAL PROTEIN [Mycobacterium bovis subsp. bovis AF2122/97]; BAC00185.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 473138 5174906 CMM_0393 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221133.1 472374 R 443906 CDS YP_001221134.1 148271573 5173079 complement(473188..474225) 1 NC_009480.1 conserved hypothetical protein (NP_215352.1| hypothetical protein Rv0837c [Mycobacterium tuberculosis H37Rv]; NP_601982.1| hypothetical protein NCgl2692 [Corynebacterium glutamicum ATCC 13032])).; Function unclear; hypothetical protein 474225 5173079 CMM_0394 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221134.1 473188 R 443906 CDS YP_001221135.1 148271574 5173943 complement(474322..474789) 1 NC_009480.1 putative membrane protein (H83813 hypothetical protein BH1312 [imported] - Bacillus halodurans (strain C-125)).; Function unclear; hypothetical protein 474789 5173943 CMM_0395 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221135.1 474322 R 443906 CDS YP_001221136.1 148271575 5175215 complement(474786..475919) 1 NC_009480.1 putative Na+ efflux ABC transporter, permease component (ZP_00227879.1| COG1668: ABC-type Na+ efflux pump, permease component [Kineococcus radiotolerans SRS30216]; AAF04136.1| hypothetical ABC transporter [Mycobacterium smegmatis]).; Function unclear; putative Na+ efflux ABC transporter, permease component 475919 5175215 CMM_0396 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Na+ efflux ABC transporter, permease component YP_001221136.1 474786 R 443906 CDS YP_001221137.1 148271576 5174119 complement(475916..476797) 1 NC_009480.1 putative ABC-Transporter, ATP binding protein (ZP_00227878.1| COG4152: ABC-type uncharacterized transport system, ATPase component [Kineococcus radiotolerans SRS30216]; AAF04137.1| hypothetical ABC transporter [Mycobacterium smegmatis]). InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Function unclear; putative ABC transporter, ATP-binding protein 476797 5174119 CMM_0397 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001221137.1 475916 R 443906 CDS YP_001221138.1 148271577 5175516 476999..477448 1 NC_009480.1 Hypothetical protein; hypothetical protein 477448 5175516 CMM_0398 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221138.1 476999 D 443906 CDS YP_001221139.1 148271578 5174223 complement(477439..478344) 1 NC_009480.1 conserved hypothetical protein, eventually Ca2+-binding (NP_978918.1| regucalcin family protein [Bacillus cereus ATCC 10987]; NP_626682.1| putative calcium-binding protein [Streptomyces coelicolor A3(2)]).; Family membership; hypothetical protein 478344 5174223 CMM_0399 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221139.1 477439 R 443906 CDS YP_001221140.1 148271579 5174273 complement(478341..479135) 1 NC_009480.1 putative short chain dehydrogenase (ZP_00226079.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAF21988.1| Subunit of 2-[hydroxy(phenyl)methyl]-succinyl-CoA DH; bbsD [Azoarcus sp. EbN1]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase 479135 5174273 CMM_0400 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase YP_001221140.1 478341 R 443906 CDS YP_001221141.1 148271580 5174847 479188..479970 1 NC_009480.1 putative short-chain alcohol dehydrogenase (ZP_00226078.1| COG1028: dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_767148.1| hypothetical oxidoreductase [Bradyrhizobium japonicum]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain alcohol dehydrogenase 479970 5174847 CMM_0401 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain alcohol dehydrogenase YP_001221141.1 479188 D 443906 CDS YP_001221142.1 148271581 5175879 complement(479989..480438) 1 NC_009480.1 hypothetical protein 480438 5175879 CMM_0402 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221142.1 479989 R 443906 CDS YP_001221143.1 148271582 5174228 480919..482340 1 NC_009480.1 putative glycerol-3-phosphate MFS permease (NP_938673.1| Putative glycerol-3-phosphate transporter [Corynebacterium diphtheriae]; AAL21184.1| MFS family, sn-glycerol-3-phosphate transport protein [Salmonella typhimurium LT2]). Responsible for glycerol-3-phosphate uptake. pfam00083, Sugar_tr, Sugar (and other) transporter. 2A0104: phosphoglycerate transporter pr; High confidence in function and specificity; putative glycerol-3-phosphate MFS permease 482340 glpT 5174228 glpT Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerol-3-phosphate MFS permease YP_001221143.1 480919 D 443906 CDS YP_001221144.1 148271583 5174121 complement(482363..483100) 1 NC_009480.1 putative two-component system response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). InterPro: Response regulator receiver domain pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system response regulator 483100 5174121 CMM_0404 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001221144.1 482363 R 443906 CDS YP_001221145.1 148271584 5174271 complement(483097..484506) 1 NC_009480.1 putative two-component system, sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.; Specificity unclear; putative two-component system, sensor kinase 484506 5174271 CMM_0405 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001221145.1 483097 R 443906 CDS YP_001221146.1 148271585 5174440 484813..486405 1 NC_009480.1 putative drug efflux MFS permease (NP_472303.1| ; NP_627413.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr,Sugar (and other) transporter. InterPro: General substrate transporters 2_A_01_02: Multidrug resistance protein; Specificity unclear; putative drug efflux MFS permease 486405 5174440 CMM_0406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative drug efflux MFS permease YP_001221146.1 484813 D 443906 CDS YP_001221147.1 148271586 5174950 complement(486491..487339) 1 NC_009480.1 putative hydrolase (ZP_00226479.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_826888.1| putative alpha/beta hydrolase fold family protein [Streptomyces avermitilis MA-4680]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; alpha/beta fold family hydrolase 487339 5174950 CMM_0407 Clavibacter michiganensis subsp. michiganensis NCPPB 382 alpha/beta fold family hydrolase YP_001221147.1 486491 R 443906 CDS YP_001221148.1 148271587 5174693 487427..488134 1 NC_009480.1 hypothetical protein 488134 5174693 CMM_0408 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221148.1 487427 D 443906 CDS YP_001221149.1 148271588 5175324 complement(488148..488861) 1 NC_009480.1 oxidoreductase (ZP_00227286.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; AAD46515.1| oxidoreductase homolog [Streptomyces albus]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative oxidoreductase 488861 5175324 CMM_0409 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221149.1 488148 R 443906 CDS YP_001221150.1 148271589 5174708 488994..489413 1 NC_009480.1 putative transcriptional regulator, MerR-family (ZP_00191407.2| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; CAE53385.1| putative transcriptional regulator, MerR family [Actinoplanes teichomyceticus]). pfam00376, MerR,MerR family regulatory protein.; Specificity unclear; MerR family transcriptional regulator 489413 5174708 CMM_0410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MerR family transcriptional regulator YP_001221150.1 488994 D 443906 CDS YP_001221151.1 148271590 5174605 489604..490074 1 NC_009480.1 hypothetical protein 490074 5174605 CMM_0411 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221151.1 489604 D 443906 CDS YP_001221152.1 148271591 5174616 490088..490267 1 NC_009480.1 hypothetical protein 490267 5174616 CMM_0412 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221152.1 490088 D 443906 CDS YP_001221153.1 148271592 5173874 complement(490374..490736) 1 NC_009480.1 hypothetical protein 490736 5173874 CMM_0413 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221153.1 490374 R 443906 CDS YP_001221154.1 148271593 5174385 490826..491362 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_899880.1| probable transcriptional regulator, MarR family [Chromobacterium violaceum ATCC 12472]; NP_348196.1| Transcriptional regulators, MarR/EmrR family [Clostridium acetobutylicum]). InterPro: Bacterial regulatory protein MarR family. pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 491362 5174385 CMM_0414 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221154.1 490826 D 443906 CDS YP_001221155.1 148271594 5174096 491439..491861 1 NC_009480.1 putative organic hydroperoxide resistance protein (NP_599276.2| stress-induced protein [Corynebacterium glutamicum ATCC 13032]; NP_834187.1| Osmotically inducible protein C [Bacillus cereus ATCC 14579]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; High confidence in function and specificity; organic hydroperoxide resistance protein 491861 osmC 5174096 osmC Clavibacter michiganensis subsp. michiganensis NCPPB 382 organic hydroperoxide resistance protein YP_001221155.1 491439 D 443906 CDS YP_001221156.1 148271595 5175279 491861..492268 1 NC_009480.1 putative membrane protein (NP_295648.1| hypothetical protein [Deinococcus radiodurans R1]; ZP_00209412.1| hypothetical protein Magn023696 [Magnetospirillum magnetotacticum]).; Function unclear; hypothetical protein 492268 5175279 CMM_0416 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221156.1 491861 D 443906 CDS YP_001221157.1 148271596 5174573 492406..492837 1 NC_009480.1 conserved hypothetical protein (NP_883401.1| conserved hypothetical protein [Bordetella parapertussis 12822]; ZP_00032237.1| COG3607: Predicted lactoylglutathione lyase [Burkholderia fungorum]). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; hypothetical protein 492837 5174573 CMM_0417 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221157.1 492406 D 443906 CDS YP_001221158.1 148271597 5175963 complement(492847..493980) 1 NC_009480.1 putative epoxide hydrolase (ZP_00229095.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_347356.1| Epoxide hydrolase,; Function unclear; putative epoxide hydrolase 493980 5175963 CMM_0418 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative epoxide hydrolase YP_001221158.1 492847 R 443906 CDS YP_001221159.1 148271598 5175979 complement(493997..495226) 1 NC_009480.1 conserved hypothetical protein, putative HTH-type transcriptional regulator (NP_737943.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_695848.1| hypothetical protein BL0662 [Bifidobacterium longum NCC2705]).; Function unclear; hypothetical protein 495226 5175979 CMM_0419 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221159.1 493997 R 443906 CDS YP_001221160.1 148271599 5175945 complement(495310..496368) 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_695267.1| probable ABC transporter permease protein for sugars [Bifidobacterium longum NCC2705]; ZP_00182437.2| COG1172:ribose/xylose/arabinose/ galactoside ABC-type transport systems, permease components Exiguobacterium sp. 255-15]). pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component.Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system.; Specificity unclear; putative sugar ABC transporter, membrane spanning protein 496368 5175945 CMM_0420 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, membrane spanning protein YP_001221160.1 495310 R 443906 CDS YP_001221161.1 148271600 5174592 complement(496365..497447) 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_695266.1| probable ABC transport system permease protein for sugars [Bifidobacterium longum NCC2705]; ZP_00066972.1| COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Microbulbifer degradans 2-40]). InterPro: Binding-system dependent bacterial transporters (araH livH/limM families) pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter, permease component 497447 5174592 CMM_0421 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221161.1 496365 R 443906 CDS YP_001221162.1 148271601 5175540 complement(497444..499018) 1 NC_009480.1 putative sugar ABC transporter, ATPase component (NP_695265.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; NP_437568.1| putative sugar uptake ABC transporter ATP-binding protein [Sinorhizobium meliloti 1021]). pfam00005, ABC_tran, ABC transporter (2 times).; Specificity unclear; putative sugar ABC transporter, ATPase component 499018 5175540 CMM_0422 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATPase component YP_001221162.1 497444 R 443906 CDS YP_001221163.1 148271602 5175151 complement(499112..500116) 1 NC_009480.1 putative sugar ABC transporter, binding protein (ZP_00121662.1| COG1879: ABC-type sugar transport system,periplasmic component [Bifidobacterium longum DJO10A]; ZP_00223066.1| COG1879: ABC-type sugar transport system,periplasmic component [Burkholderia cepacia R1808]).; Specificity unclear; putative sugar ABC transporter, binding protein 500116 5175151 CMM_0423 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, binding protein YP_001221163.1 499112 R 443906 CDS YP_001221164.1 148271603 5174638 complement(500283..501956) 1 NC_009480.1 putative sugar uptake ABC transporter, ATPase component (NP_695265.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; ZP_00223067.1| COG1129: ABC-type sugar transport system,ATPase component [Burkholderia cepacia R1808]). pfam00005,ABC_tran, ABC transporter (duplicated domain).; Specificity unclear; putative sugar uptake ABC transporter, ATPase component 501956 5174638 CMM_0424 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar uptake ABC transporter, ATPase component YP_001221164.1 500283 R 443906 CDS YP_001221165.1 148271604 5173769 complement(502082..503104) 1 NC_009480.1 putative transcriptional regulator, LacI family (NP_630441.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_822206.1| putative LacI-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The LacI family of proteins consist of transcriptional regulators related to the lac repressor. In this case, generally the sugar binding domain binds a sugar which changes the DNA binding activity of the repressor domain (pfam00356).; Specificity unclear; LacI family transcription regulator 503104 5173769 CMM_0425 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcription regulator YP_001221165.1 502082 R 443906 CDS YP_001221166.1 148271605 5175661 503366..504322 1 NC_009480.1 putative manganese-containing catalase (ZP_00235296.1| manganese catalase [Bacillus cereus G9241]; CAE09059.1| mn catalase [Thermus thermophilus]). pfam05067, Mn_catalase, Manganese containing catalase. Catalases are important antioxidant metalloenzymes that catalyse disproportionation of hydrogen peroxide, forming dioxygen and water. Two families of catalases are known,one having a heme cofactor, and this family that is a structurally distinct family containing non-heme manganese.; High confidence in function and specificity; manganese-containing catalase 504322 5175661 CMM_0426 Clavibacter michiganensis subsp. michiganensis NCPPB 382 manganese-containing catalase YP_001221166.1 503366 D 443906 CDS YP_001221167.1 148271606 5175210 506213..506389 1 NC_009480.1 hypothetical protein , weak similarity to: pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein 506389 5175210 CMM_0427 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221167.1 506213 D 443906 CDS YP_001221168.1 148271607 5175776 506602..509040 1 NC_009480.1 putative phosphoketolase (Q8YTZ6|PHK2_ANASP Probable phosphoketolase 2; NP_960507.1| hypothetical protein MAP1573c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03894, XFP, D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. Bacterial enzyme splits fructose-6-P and/or xylulose-5-P with the aid of inorganic phosphate into either acetyl-P and erythrose-4-P and/or acetyl-P and glyeraldehyde-3-P EC:4.1.2.9, EC:4.1.2.22.; Specificity unclear; putative phosphoketolase 509040 5175776 CMM_0428 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoketolase YP_001221168.1 506602 D 443906 CDS YP_001221169.1 148271608 5175259 complement(509091..509840) 1 NC_009480.1 putative secreted protein (ZP_00413710.1| S-layer homology region [Arthrobacter sp. FB24]).; Hypothetical protein; hypothetical protein 509840 5175259 CMM_0429 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221169.1 509091 R 443906 CDS YP_001221170.1 148271609 5175959 complement(509932..511758) 1 NC_009480.1 hypothetical secreted protein, putative cell-surface protein (only weak similarities, putative N-terminal RTX toxin and C-terminal fibrinogen-binding domain; ZP_00413710.1| S-layer homology region [Arthrobacter sp. FB24]).; Hypothetical protein; hypothetical protein 511758 5175959 CMM_0430 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221170.1 509932 R 443906 CDS YP_001221171.1 148271610 5175970 complement(511928..514192) 1 NC_009480.1 putative secreted hemagglutinin/hemolysin-related protein (NP_868824.1| probable fibrinogen-binding protein homolog-putative involved in cell-cell interaction [Pirellula sp. 1]; also similarities to membrane proteins of unknown function: NP_628213.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]).; Function unclear; putative hemagglutinin/hemolysin-related protein 514192 5175970 CMM_0431 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hemagglutinin/hemolysin-related protein YP_001221171.1 511928 R 443906 CDS YP_001221172.1 148271611 5175334 514407..515069 1 NC_009480.1 conserved hypothetical protein (NP_600647.1| uncharacterized low-complexity protein [Corynebacterium glutamicum ATCC 13032]; NP_628440.1| hypothetical protein [Streptomyces coelicolor A3(2)])., , pfam00805,Pentapeptide, Pentapeptide repeats (8 copies).; hypothetical protein 515069 5175334 CMM_0432 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221172.1 514407 D 443906 CDS YP_001221173.1 148271612 5175306 complement(515083..516114) 1 NC_009480.1 putative iron-siderophore ABC transporter, permease component (BAB97894.1| ABC-type transporter, permease components [Corynebacterium glutamicum ATCC 13032]; AAD29086.1| FepG [Yersinia enterocolitica]; NP_626057.1| putative iron-siderophore uptake system transmembrane component [Streptomyces coelicolor A3(2)]). pfam01032,FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporter,permease component 516114 fepG 5175306 fepG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,permease component YP_001221173.1 515083 R 443906 CDS YP_001221174.1 148271613 5173350 complement(516111..517118) 1 NC_009480.1 putative iron-siderophore ABC transporter, permease component (BAB97895.1| ABC-type transporter, permease components [Corynebacterium glutamicum ATCC 13032]; NP_626058.1| putative iron-siderophore uptake system transmembrane component [Streptomyces coelicolor A3(2)]; AAD29085.1| FepD [Yersinia enterocolitica]). InterPro: FecCD transport family pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporter,permease component 517118 fepD 5173350 fepD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,permease component YP_001221174.1 516111 R 443906 CDS YP_001221175.1 148271614 5173397 517149..518225 1 NC_009480.1 putative iron-siderophore ABC transporter, binding protein (BAC00469.1| ABC-type Fe3+-siderophores transport systems, periplasmic components [Corynebacterium glutamicum ATCC 13032]; pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative iron-siderophore ABC transporter,binding protein 518225 fepB 5173397 fepB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,binding protein YP_001221175.1 517149 D 443906 CDS YP_001221176.1 148271615 5173277 complement(518235..518756) 1 NC_009480.1 putative acetyltransferase (NP_103315.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]; BAA06228.1| regulatory protein for C-P lyase [Streptomyces griseus]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 518756 5173277 CMM_0436 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221176.1 518235 R 443906 CDS YP_001221177.1 148271616 5175333 518809..519558 1 NC_009480.1 putative SAM-dependant methyltransferase (NP_631493.1| hypothetical protein SC5C11.02. [Streptomyces coelicolor A3(2)]; NP_418726.1| putative methyltransferase [Escherichia coli K12]). pfam02390,Methyltransf_4, Putative methyltransferase.; Conserved hypothetical protein; putative SAM-dependant methyltransferase 519558 5175333 CMM_0437 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative SAM-dependant methyltransferase YP_001221177.1 518809 D 443906 CDS YP_001221178.1 148271617 5175854 complement(519626..520414) 1 NC_009480.1 putative hydrolase (NP_350247.1| Alpha/beta superfamily hydrolase [Clostridium acetobutylicum]; NP_623397.1| Hydrolases of the alpha/beta superfamily [Thermoanaerobacter tengcongensis]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 520414 5175854 CMM_0438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221178.1 519626 R 443906 CDS YP_001221179.1 148271618 5174728 complement(520414..520944) 1 NC_009480.1 putative phenolic acid decarboxylase (NP_959619.1| hypothetical protein MAP0685 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_391320.1| ferulate decarboxylase [Bacillus subtilis]). pfam05870,PA_decarbox, Phenolic acid decarboxylase (PAD). This family consists of several bacterial phenolic acid decarboxylase proteins. Phenolic acids, also called substituted cinnamic acids, are important lignin-related aromatic acids and natural constituents of plant cell walls. These acids (particularly ferulic, p-coumaric, and caffeic acids) bind the complex lignin polymer to the hemicellulose and cellulose in plants. The Phenolic acid decarboxylase (PAD) gene (pad) is transcriptionally regulated by p-coumaric, ferulic, or caffeic acid; these three acids are the three substrates of PAD.; Specificity unclear; putative phenolic acid decarboxylase 520944 padA 5174728 padA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phenolic acid decarboxylase YP_001221179.1 520414 R 443906 CDS YP_001221180.1 148271619 5175359 521008..521508 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_824165.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00081183.1| COG1846: Transcriptional regulators [Geobacter metallireducens]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein 521508 5175359 CMM_0440 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221180.1 521008 D 443906 CDS YP_001221181.1 148271620 5175141 521634..522209 1 NC_009480.1 hypothetical protein 522209 5175141 CMM_0441 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221181.1 521634 D 443906 CDS YP_001221182.1 148271621 5173917 522274..522888 1 NC_009480.1 hypothetical protein 522888 5173917 CMM_0442 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221182.1 522274 D 443906 CDS YP_001221183.1 148271622 5175363 complement(522987..523577) 1 NC_009480.1 putative MarR-family transcriptional regulator (NP_824140.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_629432.1| putative MarR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01047,MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR.; Specificity unclear; MarR family transcriptional regulator 523577 5175363 CMM_0443 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221183.1 522987 R 443906 CDS YP_001221184.1 148271623 5174343 complement(523574..525331) 1 NC_009480.1 putative MFS permease (NP_628213.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; ZP_00226711.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). TIGRFAM (TIGR00711): drug resistance transporter, EmrB/QacA subfamily.; Specificity unclear; MFS family transporter 525331 5174343 CMM_0444 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MFS family transporter YP_001221184.1 523574 R 443906 CDS YP_001221185.1 148271624 5173778 525500..525856 1 NC_009480.1 conserved hypothetical protein (ZP_00071215.1| hypothetical protein [Trichodesmium erythraeum IMS101]; NP_968301.1| putative glyoxalase [Bdellovibrio bacteriovorus HD100]). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 525856 5173778 CMM_0445 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221185.1 525500 D 443906 CDS YP_001221186.1 148271625 5175906 complement(525870..527021) 1 NC_009480.1 putative Xaa-Pro dipeptidase (NP_343867.1| Prolidase (Xaa-Pro dipeptidase) (pepQ-like3) [Sulfolobus solfataricus P2]; NP_635937.1| Xaa-Pro dipeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]).; Function unclear; putative peptidase 527021 5175906 CMM_0446 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidase YP_001221186.1 525870 R 443906 CDS YP_001221187.1 148271626 5174487 complement(527021..527329) 1 NC_009480.1 conserved hypothetical protein (NP_821812.1| hypothetical protein SAV637 [Streptomyces avermitilis MA-4680]; NP_714492.1| conserved hypothetical protein [Leptospira interrogans serovar lai str. 56601]).; hypothetical protein 527329 5174487 CMM_0447 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221187.1 527021 R 443906 CDS YP_001221188.1 148271627 5174624 complement(527347..527865) 1 NC_009480.1 hypothetical protein 527865 5174624 CMM_0448 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221188.1 527347 R 443906 CDS YP_001221189.1 148271628 5174813 complement(527872..528774) 1 NC_009480.1 hypothetical protein 528774 5174813 CMM_0449 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221189.1 527872 R 443906 CDS YP_001221190.1 148271629 5175355 complement(528865..529494) 1 NC_009480.1 putative oxidoreductase (NP_822664.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; NP_902034.1| acetoacetyl-CoA reductase [Chromobacterium violaceum ATCC 12472]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Hypothetical protein; hypothetical protein 529494 5175355 CMM_0450 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221190.1 528865 R 443906 CDS YP_001221191.1 148271630 5175143 complement(529491..530912) 1 NC_009480.1 hypothetical protein (NP_625383.1| hypothetical protein 2SCG4.05c [Streptomyces coelicolor A3(2)]; NP_625383.1| hypothetical protein 2SCG4.05c [Streptomyces coelicolor A3(2)]).; hypothetical protein 530912 5175143 CMM_0451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221191.1 529491 R 443906 CDS YP_001221192.1 148271631 5175222 complement(531050..531616) 1 NC_009480.1 putative acetyltransferase (NP_253367.1| peptide n-acetyltransferase RimI [Pseudomonas aeruginosa PA01]; ZP_00088630.1| COG0456: Acetyltransferases [Azotobacter vinelandii]). , pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 531616 5175222 CMM_0452 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221192.1 531050 R 443906 CDS YP_001221193.1 148271632 5175174 531745..532962 1 NC_009480.1 puative low-affinity inorganic phosphate permease (ZP_00227554.1| COG0306: Phosphate/sulphate permeases [Kineococcus radiotolerans SRS30216]; NP_737084.1| putative phosphate transport protein PitA [Corynebacterium efficiens YS-314]). pfam01384, PHO4, Phosphate transporter family.; High confidence in function and specificity; low affinity phosphate permease 532962 pitA 5175174 pitA Clavibacter michiganensis subsp. michiganensis NCPPB 382 low affinity phosphate permease YP_001221193.1 531745 D 443906 CDS YP_001221194.1 148271633 5173624 532974..533285 1 NC_009480.1 putative membrane protein (NP_737083.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00227553.1| hypothetical protein Krad06004394 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 533285 5173624 CMM_0454 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221194.1 532974 D 443906 CDS YP_001221195.1 148271634 5175145 533288..533998 1 NC_009480.1 conserved hypothetical protein, putative fusion protein containing duplicated domain (NP_962973.1| hypothetical protein MAP4039c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00198152.1| hypothetical protein Krad06004393 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 533998 5175145 CMM_0455 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221195.1 533288 D 443906 CDS YP_001221196.1 148271635 5175785 complement(534030..534233) 1 NC_009480.1 hypothetical protein 534233 5175785 CMM_0456 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221196.1 534030 R 443906 CDS YP_001221197.1 148271636 5174789 534450..535112 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_599627.1| transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; AAM94766.1| CalR1 [Micromonospora echinospora]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 535112 5174789 CMM_0457 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221197.1 534450 D 443906 CDS YP_001221198.1 148271637 5175954 535109..536812 1 NC_009480.1 putative MFS permease (ZP_00229023.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_599629.1| permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]). InterPro: Drug resistance transporter EmrB/QacA subfamily pfam00083,Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00711): drug resistance transport protein; Function unclear; MFS-type efflux permease 536812 5175954 CMM_0458 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MFS-type efflux permease YP_001221198.1 535109 D 443906 CDS YP_001221199.1 148271638 5174436 536932..537375 1 NC_009480.1 conserved hypothetical protein (NP_627085.1| hypothetical protein SCE20.30. [Streptomyces coelicolor A3(2)]; NP_438059.1| CONSERVED HYPOTHETICAL PROTEIN [Sinorhizobium meliloti 1021]). pfam05146, DUF704, Aha1 domain. The function of this presumed domain is unknown.; Function unclear; hypothetical protein 537375 5174436 CMM_0459 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221199.1 536932 D 443906 CDS YP_001221200.1 148271639 5175769 complement(537372..539066) 1 NC_009480.1 conserved hypothetical protein (ZP_00120870.2| hypothetical protein Blon020749 [Bifidobacterium longum DJO10A]; ZP_00218065.1| hypothetical protein Bcepa02000673 [Burkholderia cepacia R18194]).; hypothetical protein 539066 5175769 CMM_0460 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221200.1 537372 R 443906 CDS YP_001221201.1 148271640 5173895 539259..540188 1 NC_009480.1 putative permease, AEC family (NP_696444.1| hypothetical protein with unknown or transport function [Bifidobacterium longum NCC2705]; ZP_00189944.2| COG0679: Predicted permeases [Kineococcus radiotolerans SRS30216] 2a69: Auxin Efflux Carrier pfam03547, Auxin_eff, Auxin Efflux Carrier. This family of transporters are found in all domains of life.; Specificity unclear; permease AEC family 540188 5173895 CMM_0461 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease AEC family YP_001221201.1 539259 D 443906 CDS YP_001221202.1 148271641 5174254 complement(540201..540359) 1 NC_009480.1 hypothetical protein 540359 5174254 CMM_0462 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221202.1 540201 R 443906 CDS YP_001221203.1 148271642 5174324 complement(540498..540974) 1 NC_009480.1 putative acetyltransferase (ZP_00184384.1| hypothetical protein Exigu007901 [Exiguobacterium sp. 255-15]; ZP_00062966.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293] pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; putative acetyltransferase 540974 5174324 CMM_0463 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221203.1 540498 R 443906 CDS YP_001221204.1 148271643 5175808 complement(541062..542021) 1 NC_009480.1 putative sugar reductase (NP_625517.1| putative reductase [Streptomyces coelicolor A3(2)]; CAF21980.1| Sugar dehydratase [Azoarcus sp. EbN1]).; Family membership; hypothetical protein 542021 5175808 CMM_0464 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221204.1 541062 R 443906 CDS YP_001221205.1 148271644 5175922 complement(542537..543241) 1 NC_009480.1 hypothetical protein 543241 5175922 CMM_0465 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221205.1 542537 R 443906 CDS YP_001221206.1 148271645 5175896 complement(543275..544162) 1 NC_009480.1 conserved hypothetical protein (NP_828650.1| hypothetical protein SAV7474 [Streptomyces avermitilis MA-4680]; NP_293888.1| endo alpha-1,4 polygalactosaminidase,putative [Deinococcus radiodurans R1]).; Function unclear; hypothetical protein 544162 5175896 CMM_0466 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221206.1 543275 R 443906 CDS YP_001221207.1 148271646 5175743 complement(544172..544609) 1 NC_009480.1 conserved hypothetical protein (NP_695944.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]; NP_358299.1| Conserved hypothetical protein [Streptococcus pneumoniae R6]). pfam06171, DUF984,Protein of unknown function (DUF984).; Function unclear; hypothetical protein 544609 5175743 CMM_0467 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221207.1 544172 R 443906 CDS YP_001221208.1 148271647 5174395 complement(544648..544995) 1 NC_009480.1 Hypothetical protein; hypothetical protein 544995 5174395 CMM_0468 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221208.1 544648 R 443906 CDS YP_001221209.1 148271648 5175827 545154..546062 1 NC_009480.1 putative oxidoreductase (NP_636454.1| oxidoreductase [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_535107.1| oxidoreductase [Agrobacterium tumefaciens str. C58]). pfam00106, adh_short, short chain dehydrogenase; Function unclear; putative oxidoreductase 546062 5175827 CMM_0469 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221209.1 545154 D 443906 CDS YP_001221210.1 148271649 5174803 complement(546093..546659) 1 NC_009480.1 conserved hypothetical protein (NP_862390.1| MC12 [Micrococcus sp. 28]; ZP_00225867.1| hypothetical protein Krad06004329 [Kineococcus radiotolerans SRS30216]). pfam03473, MOSC, MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes.; Function unclear; hypothetical protein 546659 5174803 CMM_0470 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221210.1 546093 R 443906 CDS YP_001221211.1 148271650 5175918 546768..548468 1 NC_009480.1 putative two-component sensor histidine kinase (NP_834294.1| Phosphate regulon sensor protein phoR [Bacillus cereus ATCC 14579]; ZP_00061962.1| COG5002: Signal transduction histidine kinase [Clostridium thermocellum ATCC 27405]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component sensor histidine kinase 548468 5175918 CMM_0471 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component sensor histidine kinase YP_001221211.1 546768 D 443906 CDS YP_001221212.1 148271651 5175844 548510..549385 1 NC_009480.1 hypothetical protein 549385 5175844 CMM_0472 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221212.1 548510 D 443906 CDS YP_001221213.1 148271652 5174472 complement(549618..550475) 1 NC_009480.1 putative two-component system response regulator (ZP_00019357.1| hypothetical protein [Chloroflexus aurantiacus]; NP_602156.1| two-component system, response regulator [Corynebacterium glutamicum ATCC 13032]). InterPro: Response regulator receiver domain pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator 550475 5174472 CMM_0473 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001221213.1 549618 R 443906 CDS YP_001221214.1 148271653 5173856 complement(550605..551192) 1 NC_009480.1 putative membrane protein (only very weak similarities to histidine kinases, two-component regulators); Hypothetical protein; hypothetical protein 551192 5173856 CMM_0474 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221214.1 550605 R 443906 CDS YP_001221215.1 148271654 5175904 complement(551281..552117) 1 NC_009480.1 Exodeoxyribonuclease III (ZP_00227856.1| COG0708: Exonuclease III [Kineococcus radiotolerans SRS30216]; CAB06567.1| PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI) [Mycobacterium tuberculosis H37Rv]). , pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family.; High confidence in function and specificity; putative exonuclease III 552117 xthB 5175904 xthB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative exonuclease III YP_001221215.1 551281 R 443906 CDS YP_001221216.1 148271655 5174193 complement(556093..556488) 1 NC_009480.1 hypothetical protein 556488 5174193 CMM_0476 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221216.1 556093 R 443906 CDS YP_001221217.1 148271656 5174230 complement(556485..557234) 1 NC_009480.1 hypothetical protein , , pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; hypothetical protein 557234 5174230 CMM_0477 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221217.1 556485 R 443906 CDS YP_001221218.1 148271657 5175278 complement(557231..557785) 1 NC_009480.1 ECF sigma factor (ZP_00198063.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]; ZP_00179997.2| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Moorella thermoacetica ATCC 39073]). pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. pfam04545, Sigma70_r4, Sigma-70,region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.; Specificity unclear; putative ECF sigma factor 557785 sigZ 5175278 sigZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ECF sigma factor YP_001221218.1 557231 R 443906 CDS YP_001221219.1 148271658 5175095 557918..558391 1 NC_009480.1 conserved hypothetical protein (ZP_00189314.2| COG1302: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_626104.1| putative stress-like protein [Streptomyces coelicolor A3(2)]). pfam03780, DUF322, Protein of unknown function (DUF322). This is a family of small proteins. It includes a protein identified as an alkaline shock protein, so may be involved in stress response.; hypothetical protein 558391 5175095 CMM_0479 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221219.1 557918 D 443906 CDS YP_001221220.1 148271659 5175814 558564..559439 1 NC_009480.1 putative beta-hydroxyacid dehydrogenase (NP_822718.1| putative dehydrogenase [Streptomyces avermitilis MA-4680]; ZP_00187394.1| COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Rubrobacter xylanophilus DSM 9941]).; Specificity unclear; putative beta-hydroxyacid dehydrogenase 559439 5175814 CMM_0480 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-hydroxyacid dehydrogenase YP_001221220.1 558564 D 443906 CDS YP_001221221.1 148271660 5174601 559506..560060 1 NC_009480.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 560060 pyrE 5174601 pyrE Clavibacter michiganensis subsp. michiganensis NCPPB 382 orotate phosphoribosyltransferase YP_001221221.1 559506 D 443906 CDS YP_001221222.1 148271661 5174805 560060..562135 1 NC_009480.1 hypothetical protein (weak similarity to: Q06852|SLP1_CLOTM CELL SURFACE GLYCOPROTEIN 1 PRECURSOR (OUTER LAYER PROTEIN B)(S-LAYER PROTEIN 1)).; hypothetical protein 562135 5174805 CMM_0482 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221222.1 560060 D 443906 CDS YP_001221223.1 148271662 5172997 562242..563510 1 NC_009480.1 putative efflux MFS permease (ZP_00098466.1| COG0477: Permeases of the major facilitator superfamily [Desulfitobacterium hafniense]; NP_486255.1|; Specificity unclear; putative MFS permease 563510 5172997 CMM_0483 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221223.1 562242 D 443906 CDS YP_001221224.1 148271663 5174205 complement(563511..564308) 1 NC_009480.1 putative N-acetylglucosamine-6-phosphate deacetylase (ZP_00228023.1| COG0647: Predicted sugar phosphatases of the HAD superfamily [Kineococcus radiotolerans SRS30216]; NP_627072.1| putative N-acetylglucosamine-6-phosphate deacetylase [Streptomyces coelicolor A3(2)]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Specificity unclear; putative N-acetylglucosamine-6-phosphate deacetylase 564308 nagD 5174205 nagD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative N-acetylglucosamine-6-phosphate deacetylase YP_001221224.1 563511 R 443906 CDS YP_001221225.1 148271664 5173855 564438..565343 1 NC_009480.1 putative 3',5'-cyclic-nucleotide phosphodiesterase (ZP_00227924.1| COG1409: Predicted phosphohydrolases [Kineococcus radiotolerans SRS30216]; F70536 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17) cpdA homolog -Mycobacterium tuberculosis (strain H37RV)). pfam00149,Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases.; Specificity unclear; putative 3',5'-cyclic-nucleotide phosphodiesterase 565343 cpdA 5173855 cpdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 3',5'-cyclic-nucleotide phosphodiesterase YP_001221225.1 564438 D 443906 CDS YP_001221226.1 148271665 5173188 complement(565417..565587) 1 NC_009480.1 hypothetical protein (ZP_00197844.1| hypothetical protein Krad06004950 [Kineococcus radiotolerans SRS30216]; ZP_00052607.1| COG3237: Uncharacterized protein conserved in bacteria [Magnetospirillum magnetotacticum]).; hypothetical protein 565587 5173188 CMM_0486 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221226.1 565417 R 443906 CDS YP_001221227.1 148271666 5174918 565772..566191 1 NC_009480.1 putative membrane protein (NP_954813.1| putative membrane protein [Gordonia westfalica]; NP_628654.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 566191 5174918 CMM_0487 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221227.1 565772 D 443906 CDS YP_001221228.1 148271667 5173989 566280..568454 1 NC_009480.1 putative ATP-dependent DNA helicase (NP_823626.1| putative ATP-dependent DNA helicase [Streptomyces avermitilis MA-4680]; ZP_00226231.1| COG0514: Superfamily II DNA helicase [Kineococcus radiotolerans SRS30216]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; High confidence in function and specificity; putative ATP-dependent DNA helicase 568454 recQ2 5173989 recQ2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001221228.1 566280 D 443906 CDS YP_001221229.1 148271668 5174295 complement(568474..569520) 1 NC_009480.1 putative adenine-specific DNA-modification methylase (NP_787899.1| DNA modification methyltransferase [Tropheryma whipplei str. Twist]; NP_085633.1| DNA methyltransferase [Mesorhizobium loti MAFF303099]). pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.; Specificity unclear; putative adenine-specific DNA-modification methylase 569520 5174295 CMM_0489 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative adenine-specific DNA-modification methylase YP_001221229.1 568474 R 443906 CDS YP_001221230.1 148271669 5173413 569873..570955 1 NC_009480.1 putative membrane protein,; Hypothetical protein; hypothetical protein 570955 5173413 CMM_0490 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221230.1 569873 D 443906 CDS YP_001221231.1 148271670 5173903 571114..572013 1 NC_009480.1 putative membrane protein (ZP_00060954.1| hypothetical protein [Clostridium thermocellum ATCC 27405]; NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 572013 5173903 CMM_0491 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221231.1 571114 D 443906 CDS YP_001221232.1 148271671 5175464 572091..573335 1 NC_009480.1 conserved hypothetical protein (ZP_00227183.1| COG3844: Kynureninase [Kineococcus radiotolerans SRS30216]; ZP_00049417.2| COG3844: Kynureninase [Magnetospirillum magnetotacticum]). pfam00266,Aminotran_5, Aminotransferase class-V.; Family membership; hypothetical protein 573335 5175464 CMM_0492 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221232.1 572091 D 443906 CDS YP_001221233.1 148271672 5175332 complement(573369..574463) 1 NC_009480.1 putative NAD(P)H-dependant dehydrogenase (ZP_00226640.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_384229.1| PUTATIVE OXIDOREDUCTASE PROTEIN [Sinorhizobium meliloti 1021]). pfam01408, GFO_IDH_MocA,Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD.; Function unclear; putative oxidoreductase 574463 5175332 CMM_0493 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221233.1 573369 R 443906 CDS YP_001221234.1 148271673 5175667 574662..576896 1 NC_009480.1 putative sucrose synthase (Sucrose-UDP glucosyltransferase)(NP_681372.1| sucrose phosphate synthase [Thermosynechococcus elongatus BP-1]; NP_926553.1| sucrose phosphate synthase [Gloeobacter violaceus PCC 7421]; P31922|SUS1_HORVU Sucrose synthase 1 (Sucrose-UDP glucosyltransferase 1)). SUCROSE-CLEAVING ENZYME THAT PROVIDES UDP-GLUCOSE AND FRUCTOSE FOR VARIOUS METABOLIC PATHWAYS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Family membership; putative sucrose synthase (sucrose-UDP glucosyltransferase) 576896 5175667 CMM_0494 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sucrose synthase (sucrose-UDP glucosyltransferase) YP_001221234.1 574662 D 443906 CDS YP_001221235.1 148271674 5173465 576893..578218 1 NC_009480.1 putative glucoronosyltransferase (ZP_00240271.1| macrolide glycosyltransferase [Bacillus cereus G9241]; AAM70336.1| CalG1 [Micromonospora echinospora]). InterPro: UDP-glucoronosyl and UDP-glucosyl transferase. pfam00201,UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase.; Function unclear; putative glycosyltransferase 578218 5173465 CMM_0495 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221235.1 576893 D 443906 CDS YP_001221236.1 148271675 5175276 578576..580291 1 NC_009480.1 conserved hypothetical protein (CAB03747.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_925015.1| hypothetical protein gll2069 [Gloeobacter violaceus PCC 7421]). pfam04169, DUF404,Domain of unknown function (DUF404). pfam04174, DUF407,Domain of unknown function (DUF407).; hypothetical protein 580291 5175276 CMM_0496 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221236.1 578576 D 443906 CDS YP_001221237.1 148271676 5173008 580291..581226 1 NC_009480.1 conserved hypothetical protein (NP_961156.1| hypothetical protein MAP2222c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00164167.1| COG2307: Uncharacterized protein conserved in bacteria [Synechococcus elongatus PCC 7942]). pfam04168, DUF403,Bacterial domain of unknown function (DUF403).; hypothetical protein 581226 5173008 CMM_0497 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221237.1 580291 D 443906 CDS YP_001221238.1 148271677 5173998 581223..582068 1 NC_009480.1 conserved hypothetical protein (NP_961155.1| hypothetical protein MAP2221c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00213669.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Burkholderia cepacia R18194]). , pfam01841,Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Function unclear; hypothetical protein 582068 5173998 CMM_0498 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221238.1 581223 D 443906 CDS YP_001221239.1 148271678 5175033 582124..583041 1 NC_009480.1 putative lysophospholipase (NP_622099.1| Lysophospholipase [Thermoanaerobacter tengcongensis]; NP_972747.1| hydrolase, alpha/beta fold family [Treponema denticola ATCC 35405]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative lysophospholipase 583041 5175033 CMM_0499 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lysophospholipase YP_001221239.1 582124 D 443906 CDS YP_001221240.1 148271679 5175669 583038..583532 1 NC_009480.1 putative acetyltransferase (ZP_00109910.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Nostoc punctiforme]; NP_939442.1| Putative acetyltransferase [Corynebacterium diphtheriae]).; Function unclear; putative acetyltransferase 583532 5175669 CMM_0500 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221240.1 583038 D 443906 CDS YP_001221241.1 148271680 5174047 complement(583604..586429) 1 NC_009480.1 conserved hypothetical protein, putative cell wall/surface protein; hypothetical protein 586429 5174047 CMM_0501 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221241.1 583604 R 443906 CDS YP_001221242.1 148271681 5175153 complement(586426..588303) 1 NC_009480.1 putative serine protease, family S53 (NP_827126.1| hypothetical protein [Streptomyces avermitilis MA-4680]). pfam00082, Peptidase_S8, Subtilase family. Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see pfam00089).; Function unclear; serine protease 588303 5175153 CMM_0502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001221242.1 586426 R 443906 CDS YP_001221243.1 148271682 5173391 588673..589404 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_630409.1| transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_639852.1| putative lactone-dependent transcriptional regulator (TetR-family), MmfR [Streptomyces coelicolor A3(2)]). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 589404 5173391 CMM_0503 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221243.1 588673 D 443906 CDS YP_001221244.1 148271683 5174607 complement(589476..591650) 1 NC_009480.1 putative non-hemolytic phospholipase C (NP_900579.1| non-hemolytic phospholipase C precursor [Chromobacterium violaceum ATCC 12472]; A36143 phospholipase C (EC 3.1.4.3), nonhemolytic - Pseudomonas aeruginosa). pfam04185, Phosphoesterase, Phosphoesterase family. This family includes both bacterial phospholipase C enzymes EC:3.1.4.3, but also eukaryotic acid phosphatases EC:3.1.3.2. pfam05506, DUF756, Domain of unknown function (DUF756). This domain is found, normally as a tandem repeat, at the C-terminus of bacterial phospholipase C proteins.; Function unclear; putative phospholipase C 591650 5174607 CMM_0504 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phospholipase C YP_001221244.1 589476 R 443906 CDS YP_001221245.1 148271684 5173484 complement(591934..592566) 1 NC_009480.1 putative alkylated DNA repair protein (NP_822306.1| putative alkylated DNA repair protein [Streptomyces avermitilis MA-4680]; NP_215515.1| Alkylated DNA repair protein [Mycobacterium tuberculosis H37Rv]). alkb: alkylated DNA repair protein AlkB; Function unclear; DNA repair system specific for alkylated DNA 592566 alkB 5173484 alkB Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA repair system specific for alkylated DNA YP_001221245.1 591934 R 443906 CDS YP_001221246.1 148271685 5173392 complement(592631..593311) 1 NC_009480.1 conserved membrane protein (NP_832507.1| Integral membrane protein [Bacillus cereus ATCC 14579]; ZP_00212776.1| hypothetical protein Bcepa02005818 [Burkholderia cepacia R18194]).; Conserved hypothetical protein; hypothetical protein 593311 5173392 CMM_0506 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221246.1 592631 R 443906 CDS YP_001221247.1 148271686 5173463 593390..594439 1 NC_009480.1 putative lipoate-protein ligase A (ZP_00227712.1| COG0095: Lipoate-protein ligase A [Kineococcus radiotolerans SRS30216]; T46683 probable lipoate protein ligase snoP [imported] - Streptomyces nogalater). CREATES AN AMIDE LINKAGE THAT JOINS THE FREE CARBOXYL GROUP OF LIPOIC ACID TO THE EPSILON-AMINO GROUP OF A SPECIFIC LYSINE RESIDUE IN LIPOATE-DEPENDENT ENZYMES. THE ENZYME CATALYZES BOTH THE ATP-DEPENDENT ACTIVATION OF LIPOATE TO LIPOYL-AMP AND THE TRANSFER OF THE ACTIVATED LIPOYL ON THE APOPROTEINS (BY SIMILARITY). InterPro: Biotin/lipoate A/B protein ligase family lipoyltrans: lipoyltransferase and lipoate protein ligase pfam03099, BPL_LipA_LipB,Biotin/lipoate A/B protein ligase family. This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites.; Specificity unclear; putative lipoate-protein ligase A 594439 lplA 5173463 lplA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lipoate-protein ligase A YP_001221247.1 593390 D 443906 CDS YP_001221248.1 148271687 5175060 complement(594698..594982) 1 NC_009480.1 putative acetyltransferase (NP_631766.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00225610.1| COG2388: Predicted acetyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative acetyltransferase 594982 5175060 CMM_0508 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221248.1 594698 R 443906 CDS YP_001221249.1 148271688 5175328 complement(595050..595268) 1 NC_009480.1 hypothetical protein 595268 5175328 CMM_0509 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221249.1 595050 R 443906 CDS YP_001221250.1 148271689 5174154 complement(595269..595616) 1 NC_009480.1 hypothetical protein 595616 5174154 CMM_0510 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221250.1 595269 R 443906 CDS YP_001221251.1 148271690 5175029 595865..596761 1 NC_009480.1 conserved hypothetical protein (N-terminal: AAD27613.1| 57 kilodalton cell surface protein precursor Msa2 [Renibacterium salmoninarum]; NP_821231.1| hypothetical protein SAV57 [Streptomyces avermitilis MA-4680]). C-terminal half: NP_241888.1| BH1022 unknown conserved protein in bacilli [Bacillus halodurans C-125]; NP_828397.1| hypothetical protein SAV7221 [Streptomyces avermitilis MA-4680])., pfam01833, TIG, IPT/TIG domain.; hypothetical protein 596761 5175029 CMM_0511 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221251.1 595865 D 443906 CDS YP_001221252.1 148271691 5174313 complement(596758..597207) 1 NC_009480.1 putative membrane protein (weak similarities to: NP_656679.1| hypothetical protein predicted by GeneMark [Bacillus anthracis A2012]).; hypothetical protein 597207 5174313 CMM_0512 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221252.1 596758 R 443906 CDS YP_001221253.1 148271692 5175441 complement(597320..598960) 1 NC_009480.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 598960 pgmA 5175441 pgmA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglucomutase YP_001221253.1 597320 R 443906 CDS YP_001221254.1 148271693 5174619 599010..599966 1 NC_009480.1 Prephenate dehydratase (|NP_628146.1| prephenate dehydratase [Streptomyces coelicolor A3(2)]; ZP_00058942.1| COG0077: Prephenate dehydratase [Thermobifida fusca]). pfam00800, PDT, Prephenate dehydratase. This protein is involved in Phenylalanine biosynthesis. This protein catalyses the decarboxylation of prephenate to phenylpyruvate. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Pairs of ACT domains bind specifically to a particular amino acid leading to regulation of the linked enzyme.; High confidence in function and specificity; hypothetical protein 599966 pheA 5174619 pheA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221254.1 599010 D 443906 CDS YP_001221255.1 148271694 5174596 600028..601308 1 NC_009480.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 601308 serS 5174596 serS Clavibacter michiganensis subsp. michiganensis NCPPB 382 seryl-tRNA synthetase YP_001221255.1 600028 D 443906 CDS YP_001221256.1 148271695 5173199 601305..602126 1 NC_009480.1 putative hydrolase (ZP_00226154.1| COG0561: Predicted hydrolases of the HAD superfamily [Kineococcus radiotolerans SRS30216]; NP_789662.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]).; Function unclear; HAD family hydrolase 602126 5173199 CMM_0516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 HAD family hydrolase YP_001221256.1 601305 D 443906 CDS YP_001221257.1 148271696 5175395 602512..603657 1 NC_009480.1 putative transcriptional regulator/attenuator, LytR family(NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]; NP_627264.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). , pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Function unclear; LytR family transcriptional regulator 603657 5175395 CMM_0517 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LytR family transcriptional regulator YP_001221257.1 602512 D 443906 CDS YP_001221258.1 148271697 5172939 604230..604763 1 NC_009480.1 hypothetical protein 604763 5172939 CMM_0518 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221258.1 604230 D 443906 CDS YP_001221259.1 148271698 5174209 604825..605892 1 NC_009480.1 putative transcriptional regulator, LacI family (BAD02385.1| LacI/GalR family transcriptional repressor [Streptomyces thermoviolaceus]; NP_628912.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; hypothetical protein 605892 5174209 CMM_0519 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221259.1 604825 D 443906 CDS YP_001221260.1 148271699 5174382 606062..606760 1 NC_009480.1 conserved hypothetical protein (ZP_00226605.1| COG3828: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_624682.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 606760 5174382 CMM_0520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221260.1 606062 D 443906 CDS YP_001221261.1 148271700 5173863 606778..607854 1 NC_009480.1 putative oxidoreductase/dehydrogenase (ZP_00226604.1| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_770032.1| dehydrogenase [Bradyrhizobium japonicum USDA 110]). pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. InterPro: Oxidoreductase C-terminal.; Function unclear; putative oxidoreductase/dehydrogenase 607854 5173863 CMM_0521 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase/dehydrogenase YP_001221261.1 606778 D 443906 CDS YP_001221262.1 148271701 5173101 607946..608311 1 NC_009480.1 hypothetical protein 608311 5173101 CMM_0522 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221262.1 607946 D 443906 CDS YP_001221263.1 148271702 5174446 complement(608351..609706) 1 NC_009480.1 glycosyl hydrolase, family 13 (NP_960521.1| hypothetical protein MAP1587c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_737573.1| putative amylase [Corynebacterium efficiens YS-314]). InterPro: Glycoside hydrolase family 13 pfam00128, Alpha-amylase, Alpha amylase, catalytic domain.; High confidence in function and specificity; glycosy hydrolase family protein 609706 5174446 CMM_0523 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycosy hydrolase family protein YP_001221263.1 608351 R 443906 CDS YP_001221264.1 148271703 5175271 complement(610366..611445) 1 NC_009480.1 hypothetical protein 611445 5175271 CMM_0524 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221264.1 610366 R 443906 CDS YP_001221265.1 148271704 5175740 complement(611442..611858) 1 NC_009480.1 putative transcriptional regulator, PadR family (NP_687299.1| conserved hypothetical protein [Streptococcus agalactiae 2603V/R]; NP_422202.1| conserved hypothetical protein [Caulobacter crescentus CB15]). pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.; Specificity unclear; PadR family transcriptional regulator 611858 5175740 CMM_0525 Clavibacter michiganensis subsp. michiganensis NCPPB 382 PadR family transcriptional regulator YP_001221265.1 611442 R 443906 CDS YP_001221266.1 148271705 5174485 612006..612341 1 NC_009480.1 hypothetical protein 612341 5174485 CMM_0526 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221266.1 612006 D 443906 CDS YP_001221267.1 148271706 5174470 612444..613211 1 NC_009480.1 putative membrane protein, possible preprotein translocase (NP_627080.1| putative membrane protein. [Streptomyces coelicolor A3(2)]; ZP_00057695.1| COG0706: Preprotein translocase subunit YidC [Thermobifida fusca]). pfam02096, 60KD_IMP, 60Kd inner membrane protein.; Conserved hypothetical protein; hypothetical protein 613211 5174470 CMM_0527 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221267.1 612444 D 443906 CDS YP_001221268.1 148271707 5173886 613276..614184 1 NC_009480.1 putative metal-dependent hydrolase (NP_796992.1| hypothetical protein VP0613 [Vibrio parahaemolyticus RIMD 2210633]; CAG19181.1| hypothetical metal-dependent hydrolase [Photobacterium profundum]).; Function unclear; putative metal-dependent hydrolase 614184 5173886 CMM_0528 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal-dependent hydrolase YP_001221268.1 613276 D 443906 CDS YP_001221269.1 148271708 5173238 614297..614839 1 NC_009480.1 hypothetical protein 614839 5173238 CMM_0529 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221269.1 614297 D 443906 CDS YP_001221270.1 148271709 5173110 614857..615891 1 NC_009480.1 putative oxidoreductase (ZP_00228825.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_629103.1| putative aldoketoreductase [Streptomyces coelicolor A3(2)]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 615891 5173110 CMM_0530 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221270.1 614857 D 443906 CDS YP_001221271.1 148271710 5174882 615988..616755 1 NC_009480.1 putative 1-acylglycerol-3-phosphate O-acyltransferase (NP_822660.1| putative 1-acylglycerol-3-phosphate O-acyltransferase [Streptomyces avermitilis MA-4680]; NP_602082.1| 1-acyl-sn-glycerol-3-phosphate acyltransferase [Corynebacterium glutamicum ATCC 13032]). , pfam01553, Acyltransferase, Acyltransferase.; Specificity unclear; putative 1-acylglycerol-3-phosphate O-acyltransferase 616755 plsC 5174882 plsC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 1-acylglycerol-3-phosphate O-acyltransferase YP_001221271.1 615988 D 443906 CDS YP_001221272.1 148271711 5173307 complement(617075..617491) 1 NC_009480.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 617491 panD 5173307 panD Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate alpha-decarboxylase YP_001221272.1 617075 R 443906 CDS YP_001221273.1 148271712 5175419 617722..618813 1 NC_009480.1 putative tRNA processing ribonuclease BN (RNase BN)(NP_822167.1| putative membrane protein [Streptomyces avermitilis MA-4680]; BAB98344.1| tRNA-processing ribonuclease BN [Corynebacterium glutamicum ATCC 13032]). rbn: ribonuclease BN putative pfam03631, Ribonuclease_BN,Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation.; Function unclear; putative tRNA processing ribonuclease BN 618813 5175419 CMM_0533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tRNA processing ribonuclease BN YP_001221273.1 617722 D 443906 CDS YP_001221274.1 148271713 5173469 complement(618856..620382) 1 NC_009480.1 putative deoxyribodipyrimidine photolyase (NP_108272.1| blue light photoreceptor cryptochrome [Mesorhizobium loti MAFF303099]; NP_531913.1| DNA photolyase [Agrobacterium tumefaciens str. C58]). pfam00875, DNA_photolyase, DNA photolyase. This domain binds a light harvesting cofactor. pfam03441,FAD_binding_7, FAD binding domain of DNA photolyase.; High confidence in function and specificity; deoxyribodipyrimidine photo-lyase 620382 phrB 5173469 phrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 deoxyribodipyrimidine photo-lyase YP_001221274.1 618856 R 443906 CDS YP_001221275.1 148271714 5173746 620529..621914 1 NC_009480.1 putative glycosyl transferase (weak similarities to: NP_787164.1| glycosyltransferase [Tropheryma whipplei str. Twist]; NP_808963.1| putative glycosyltransferase [Bacteroides thetaiotaomicron VPI-5482]) pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Hypothetical protein; putative glycosyl transferase 621914 5173746 CMM_0535 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221275.1 620529 D 443906 CDS YP_001221276.1 148271715 5175522 complement(621911..622354) 1 NC_009480.1 transcriptional regulator, MarR family (NP_103003.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]; NP_631765.1| putative marR-family regulatory protein [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 622354 5175522 CMM_0536 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221276.1 621911 R 443906 CDS YP_001221277.1 148271716 5173456 complement(622675..623469) 1 NC_009480.1 putative transcriptional regulator (NP_213217.1| transcriptional regulator (PhoB-like) [Aquifex aeolicus]; NP_831082.1| Two-component response regulator [Bacillus cereus ATCC 14579]; NP_627031.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative transcriptional regulator 623469 5173456 CMM_0537 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001221277.1 622675 R 443906 CDS YP_001221278.1 148271717 5173050 complement(623866..624504) 1 NC_009480.1 uppA; Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 624504 upp 5173050 upp Clavibacter michiganensis subsp. michiganensis NCPPB 382 uracil phosphoribosyltransferase YP_001221278.1 623866 R 443906 CDS YP_001221279.1 148271718 5173149 624573..625022 1 NC_009480.1 putative cytosine/adenosine deaminase (ZP_00225554.1| COG0590: Cytosine/adenosine deaminases [Kineococcus radiotolerans SRS30216]; NP_825357.1| putative deaminase [Streptomyces avermitilis MA-4680]). pfam00383, dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region.; High confidence in function and specificity; putative cytosine/adenosine deaminase 625022 5173149 CMM_0539 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytosine/adenosine deaminase YP_001221279.1 624573 D 443906 CDS YP_001221280.1 148271719 5175494 complement(625050..625583) 1 NC_009480.1 conserved hypothetical prtotein (NP_624782.1| conserved hypothetical protein SCF76.03 [Streptomyces coelicolor A3(2)]; NP_830758.1| hypothetical protein [Bacillus cereus ATCC 14579]). pfam07336, DUF1470, Protein of unknown function (DUF1470). COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]; hypothetical protein 625583 5175494 CMM_0540 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221280.1 625050 R 443906 CDS YP_001221281.1 148271720 5174292 625636..626043 1 NC_009480.1 Region created by contig update; putative carboxymuconolactone decarboxylase-like protein 626043 5174292 CMM_0541 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxymuconolactone decarboxylase-like protein YP_001221281.1 625636 D 443906 CDS YP_001221282.1 148271721 5173072 626040..626948 1 NC_009480.1 putative phosphotriesterase-family protein (NP_625331.1| putative phosphotriesterase-family protein [Streptomyces coelicolor A3(2)]; NP_465494.1|; Function unclear; putative phosphotriesterase-family protein 626948 5173072 CMM_0542 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphotriesterase-family protein YP_001221282.1 626040 D 443906 CDS YP_001221283.1 148271722 5173377 complement(626945..627862) 1 NC_009480.1 putative metal efflux transport protein, CDF family (NP_826229.1| putative transport protein [Streptomyces avermitilis MA-4680]; ZP_00109098.1| COG0053: Predicted Co/Zn/Cd cation transporters [Nostoc punctiforme]). pfam01545, Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; Specificity unclear; CDF family metal efflux transport protein 627862 5173377 CMM_0543 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CDF family metal efflux transport protein YP_001221283.1 626945 R 443906 CDS YP_001221284.1 148271723 5173415 627994..628869 1 NC_009480.1 pyrroline-5-carboxylate reductase (ZP_00057049.1| COG0345: Pyrroline-5-carboxylate reductase [Thermobifida fusca]; NP_737040.1| pyrroline-5-carboxylate reductase [Corynebacterium efficiens YS-314]). proC: pyrroline-5-carboxylate reductase pfam01089, P5CR, Delta 1-pyrroline-5-carboxylate reductase.; High confidence in function and specificity; hypothetical protein 628869 proC 5173415 proC Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221284.1 627994 D 443906 CDS YP_001221285.1 148271724 5175803 complement(628910..629578) 1 NC_009480.1 putative K+ transporter, Trk family, NAD-binding component (ZP_00058665.1| COG0569: K+ transport systems,NAD-binding component [Thermobifida fusca]; ZP_00096571.1| COG0569: K+ transport systems, NAD-binding component [Novosphingobium aromaticivorans]). , pfam02254,TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins., pfam02080, TrkA_C, TrkA-C domain.; High confidence in function and specificity; potassium uptake system NAD-binding protein 629578 trkA 5175803 trkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 potassium uptake system NAD-binding protein YP_001221285.1 628910 R 443906 CDS YP_001221286.1 148271725 5175214 complement(629643..631067) 1 NC_009480.1 putative K+-transporter, membrane component; Trk family (ZP_00226587.1| COG0168: Trk-type K+ transport systems, membrane components [Kineococcus radiotolerans SRS30216]; ZP_00058666.1| COG0168: Trk-type K+ transport systems, membrane components [Thermobifida fusca]). InterPro: Cation transport protein pfam02386, TrkH, Cation transport protein. TIGRFAM (TIGR00933): K+ Transporter (Trk) Family pro; High confidence in function and specificity; Trk family potassium uptake protein 631067 trkG 5175214 trkG Clavibacter michiganensis subsp. michiganensis NCPPB 382 Trk family potassium uptake protein YP_001221286.1 629643 R 443906 CDS YP_001221287.1 148271726 5175368 631147..631695 1 NC_009480.1 transcriptional regulator, ArsR family (NP_898749.1| putative ArsR-family regulator [Rhodococcus erythropolis]; NP_630901.1| putative ArsR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01022, HTH_5, Bacterial regulatory protein,arsR family. Members of this family contains a DNA binding 'helix-turn-helix' motif.; Specificity unclear; ArsR family transcriptional regulator 631695 5175368 CMM_0547 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ArsR family transcriptional regulator YP_001221287.1 631147 D 443906 CDS YP_001221288.1 148271727 5173296 631818..632057 1 NC_009480.1 putative DNA-binding protein, putative excisionase (NP_825908.1| hypothetical protein SAV4731 [Streptomyces avermitilis MA-4680]; NP_334930.1| excisionase, putative [Mycobacterium tuberculosis CDC1551]). InterPro: Bacterial regulatory protein LacI family , weak similarity to: COG3311, AlpA, Predicted transcriptional regulator [Transcription].; Function unclear; putative DNA-binding protein, putative excisionase 632057 5173296 CMM_0548 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-binding protein, putative excisionase YP_001221288.1 631818 D 443906 CDS YP_001221289.1 148271729 5173062 complement(632357..633196) 1 NC_009480.1 putative phosphoserine phosphatase (CAB55344.1| phosphoserine phosphatase [Streptomyces coelicolor A3(2)]; ZP_00227480.1| COG0560: Phosphoserine phosphatase [Kineococcus radiotolerans SRS30216]). InterPro: Haloacid dehalogenase/epoxide hydrolase family serB: phosphoserine phosphatase SerB. pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; High confidence in function and specificity; putative phosphoserine phosphatase 633196 serB1 5173062 serB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoserine phosphatase YP_001221289.1 632357 R 443906 CDS YP_001221290.1 148271728 5175250 633187..633450 1 NC_009480.1 putative thioredoxin (ZP_00227479.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Kineococcus radiotolerans SRS30216]; CAB00934.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). redox_disulf_1: redox-active disulfide; Function unclear; putative thioredoxin 633450 5175250 CMM_0550 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001221290.1 633187 D 443906 CDS YP_001221291.1 148271730 5173187 633485..633787 1 NC_009480.1 Region created by contig update; hypothetical protein 633787 5173187 CMM_0551 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221291.1 633485 D 443906 CDS YP_001221292.1 148271731 5173242 633849..634880 1 NC_009480.1 putative transcriptional regulator, LacI family (CAC49322.1| putative transcriptional regulator, LacI family protein [Sinorhizobium meliloti]; B65179 ribose operon repressor - Escherichia coli (strain K-12)). InterPro: Periplasmic binding proteins and sugar binding domain LacI family pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcription regulator 634880 5173242 CMM_0552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcription regulator YP_001221292.1 633849 D 443906 CDS YP_001221293.1 148271732 5173736 634993..636306 1 NC_009480.1 putative sugar MFS permease (CAD47863.1| putative inositol transport protein [Arthrobacter nicotinovorans]; NP_786681.1| sugar transport protein [Lactobacillus plantarum WCFS1]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative sugar MFS-permease 636306 5173736 CMM_0553 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar MFS-permease YP_001221293.1 634993 D 443906 CDS YP_001221294.1 148271733 5173093 636303..637142 1 NC_009480.1 putative hydrolase (NP_350247.1| Alpha/beta superfamily hydrolase [Clostridium acetobutylicum ATCC 824]; NP_623397.1| Hydrolases of the alpha/beta superfamily [Thermoanaerobacter tengcongensis]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 637142 5173093 CMM_0554 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221294.1 636303 D 443906 CDS YP_001221295.1 148271734 5173410 637139..638380 1 NC_009480.1 conserved hypothetical protein (NP_624916.1| conserved hypothetical protein SCF55.28c [Streptomyces coelicolor A3(2)]; NP_601589.2| hypothetical protein NCgl2305 [Corynebacterium glutamicum ATCC13032]).; Function unclear; hypothetical protein 638380 5173410 CMM_0555 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221295.1 637139 D 443906 CDS YP_001221296.1 148271735 5173020 complement(638377..639012) 1 NC_009480.1 putative membrane protein (NP_978925.1| membrane protein, putative [Bacillus cereus ATCC 10987]; ZP_00228655.1| hypothetical protein Krad06001037 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 639012 5173020 CMM_0556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221296.1 638377 R 443906 CDS YP_001221297.1 148271736 5173335 complement(639092..639307) 1 NC_009480.1 hypothetical protein 639307 5173335 CMM_0557 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221297.1 639092 R 443906 CDS YP_001221298.1 148271737 5173576 complement(639386..639718) 1 NC_009480.1 hypothetical protein 639718 5173576 CMM_0558 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221298.1 639386 R 443906 CDS YP_001221299.1 148271738 5173967 complement(639896..640306) 1 NC_009480.1 hypothetical protein 640306 5173967 CMM_0559 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221299.1 639896 R 443906 CDS YP_001221300.1 148271739 5172942 complement(640299..641534) 1 NC_009480.1 putative transcriptional regulator (NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]; ZP_00058848.1| COG1316: Transcriptional regulator [Thermobifida fusca]). lytR_cpsA_psr: cell envelope-related fu pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Specificity unclear; putative transcriptional regulator 641534 5172942 CMM_0560 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001221300.1 640299 R 443906 CDS YP_001221301.1 148271740 5173604 complement(641710..643020) 1 NC_009480.1 Aspartyl-tRNA synthetase (Aspartate-tRNA ligase) (NP_789687.1| aspartyl-tRNA synthetase [Tropheryma whipplei TW08/27]; NP_831934.1| Aspartyl-tRNA synthetase [Bacillus cereus ATCC 14579]). pfam01336, tRNA_anti, OB-fold nucleic acid binding domain. This family contains OB-fold domains that bind to nucleic acids. The family includes the anti-codon binding domain of lysyl, aspartyl,and asparaginyl-tRNA synthetases (See pfam00152). pfam00152, tRNA-synt_2, tRNA synthetases class II (D, K and N).; High confidence in function and specificity; aspartyl-tRNA synthetase 643020 aspS 5173604 aspS Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartyl-tRNA synthetase YP_001221301.1 641710 R 443906 CDS YP_001221302.1 148271741 5174971 643133..643966 1 NC_009480.1 conserved hypothetical protein (ZP_00059424.1| COG1540: Uncharacterized proteins, homologs of lactam utilization protein B [Thermobifida fusca]; Q7MZI3|Y7A4_PHOLL Hypothetical UPF0271 protein plu4304). pfam03746, LamB_YcsF, LamB/YcsF family. The exact molecular function of the proteins in this family is unknown.; Function unclear; hypothetical protein 643966 5174971 CMM_0562 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221302.1 643133 D 443906 CDS YP_001221303.1 148271742 5172958 643963..644583 1 NC_009480.1 putative allophanate hydrolase subunit (NP_534404.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; ZP_00125164.1| COG1984: Allophanate hydrolase subunit 2 [Pseudomonas syringae pv. syringae B728a]). pfam02682, AHS1,Allophanate hydrolase subunit 1.; Function unclear; putative allophanate hydrolase subunit 644583 5172958 CMM_0563 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative allophanate hydrolase subunit YP_001221303.1 643963 D 443906 CDS YP_001221304.1 148271743 5172926 644580..645497 1 NC_009480.1 putative allophanate hydrolase subunit 2 (ZP_00059426.1| COG1984: Allophanate hydrolase subunit 2 [Thermobifida fusca]; ZP_00168285.1| COG1984: Allophanate hydrolase subunit 2 [Ralstonia eutropha JMP134]). pfam02626, AHS2, Allophanate hydrolase subunit 2. This domain forms the second subunit of allophanate hydrolase.; Specificity unclear; putative allophanate hydrolase subunit 645497 5172926 CMM_0564 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative allophanate hydrolase subunit YP_001221304.1 644580 D 443906 CDS YP_001221305.1 148271744 5172968 complement(645549..646376) 1 NC_009480.1 putative membrane protein (NP_822890.1| hypothetical protein SAV1714 [Streptomyces avermitilis MA-4680]; ZP_00228318.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]).; hypothetical protein 646376 5172968 CMM_0565 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221305.1 645549 R 443906 CDS YP_001221306.1 148271745 5172979 complement(646496..648985) 1 NC_009480.1 putative excinuclease ABC subunit, UvrA paralog (NP_625216.1| putative excinuclease ABC subunit A [Streptomyces coelicolor A3(2)]; ZP_00226049.1| COG0178: Excinuclease ATPase subunit [Kineococcus radiotolerans SRS30216]). The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB the uvrA molecules dissociate (By similarity).; Function unclear; putative excinuclease ABC subunit A 648985 5172979 CMM_0566 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative excinuclease ABC subunit A YP_001221306.1 646496 R 443906 CDS YP_001221307.1 148271746 5173006 complement(649537..650580) 1 NC_009480.1 putative RNA polymerase sigma 70 factor (subfamily principal sigma factors) , InterPro: Sigma-70 factor family., pfam00140, Sigma70_r1_2, Sigma-70 factor, region 1.2., pfam04542, Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. , pfam04539, Sigma70_r3, Sigma-70 region 3. ,pfam04545, Sigma70_r4, Sigma-70, region 4.; Specificity unclear; putative RNA polymerase sigma 70 factor 650580 sigB 5173006 sigB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNA polymerase sigma 70 factor YP_001221307.1 649537 R 443906 CDS YP_001221308.1 148271747 5175818 650896..651540 1 NC_009480.1 putative phosphoglycerate mutase (NP_787883.1| phosphoglycerate mutase [Tropheryma whipplei str. Twist]; NP_628636.1| putative phosphoglycerate mutase [Streptomyces coelicolor A3(2)]). pfam00300, PGAM,Phosphoglycerate mutase family.; Specificity unclear; putative phosphoglycerate mutase 651540 5175818 CMM_0568 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoglycerate mutase YP_001221308.1 650896 D 443906 CDS YP_001221309.1 148271748 5172989 651540..652148 1 NC_009480.1 putative thioredoxin, maybe involved in cytochrome C biogenesis (AAS20117.1| hypothetical protein [Arthrobacter aurescens]; ZP_00227205.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Kineococcus radiotolerans SRS30216])., , InterPro: Thioredoxin, dsbE: periplasmic protein thiol:disulfide; Specificity unclear; putative thioredoxin 652148 ccbD 5172989 ccbD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001221309.1 651540 D 443906 CDS YP_001221310.1 148271749 5173561 652149..652889 1 NC_009480.1 Cytochrome c-type biogenesis protein, membrane component (AAS20063.1| cytochrome biogenesis related protein [Arthrobacter aurescens]; NP_825976.1| putative cytochrome C biogenesis membrane protein [Streptomyces avermitilis MA-4680]). , , pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region. This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins.; High confidence in function and specificity; cytochrome C biogenesis membrane protein 652889 ccdA 5173561 ccdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytochrome C biogenesis membrane protein YP_001221310.1 652149 D 443906 CDS YP_001221311.1 148271750 5173680 652873..654519 1 NC_009480.1 putative cytochrome C biogenesis membrane protein (AAS20089.1| putative cytochrome c biogenesis membrane protein [Arthrobacter aurescens]; ZP_00227402.1| COG1333: ResB protein required for cytochrome c biosynthesis [Kineococcus radiotolerans SRS30216]). , , pfam05140,ResB, ResB-like family. This family includes both ResB and cytochrome c biogenesis proteins.; High confidence in function and specificity; putative cytochrome C biogenesis membrane protein 654519 resB 5173680 resB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome C biogenesis membrane protein YP_001221311.1 652873 D 443906 CDS YP_001221312.1 148271751 5174493 654516..655541 1 NC_009480.1 putative cytochrome c biogenesis protein, ABC transporter ATPase component(NP_789692.1| putative cytochrome biogenesis protein [Tropheryma whipplei TW08/27]; AAS20090.1| cytochrome biogenesis protein [Arthrobacter aurescens]). , , pfam01578, Cytochrom_C_asm,Cytochrome C assembly protein.; High confidence in function and specificity; putative cytochrome C-type biogenesis protein 655541 resC 5174493 resC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome C-type biogenesis protein YP_001221312.1 654516 D 443906 CDS YP_001221313.1 148271752 5174571 complement(655571..656554) 1 NC_009480.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 656554 menC 5174571 menC Clavibacter michiganensis subsp. michiganensis NCPPB 382 O-succinylbenzoate synthase YP_001221313.1 655571 R 443906 CDS YP_001221314.1 148271753 5174924 656631..657806 1 NC_009480.1 putative cytosine-specific DNA methylase (NP_927946.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; NP_422420.1| DNA-cytosine methyltransferase [Caulobacter crescentus CB15]). , , pfam00145, DNA_methylase, C-5 cytosine-specific DNA methylase.; Specificity unclear; putative cytosine-specific DNA methylase 657806 5174924 CMM_0574 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytosine-specific DNA methylase YP_001221314.1 656631 D 443906 CDS YP_001221315.1 148271754 5173023 657850..658593 1 NC_009480.1 hypothetical protein, , weak similarity to: pfam01541, GIY-YIG, GIY-YIG catalytic domain. This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC), bacteriophage T4 endonucleases segA, segB, segC, segD and segE; it is also found in putative endonucleases encoded by group I introns of fungi and phage.; hypothetical protein 658593 5173023 CMM_0575 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221315.1 657850 D 443906 CDS YP_001221316.1 148271755 5173042 658675..659586 1 NC_009480.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 659586 menB 5173042 menB Clavibacter michiganensis subsp. michiganensis NCPPB 382 naphthoate synthase YP_001221316.1 658675 D 443906 CDS YP_001221317.1 148271756 5174090 659612..660799 1 NC_009480.1 O-succinylbenzoate-CoA ligase (NP_789066.1| O-succinylbenzoic acid--CoA ligase [Tropheryma whipplei TW08/27]; NP_599697.1| o-succinylbenzoate-CoA ligase [Corynebacterium glutamicum ATCC 13032]). Involved in menaquinone biosynthesis. pfam00501, AMP-binding, AMP-binding enzyme.; High confidence in function and specificity; O-succinylbenzoate--CoA ligase 660799 menE 5174090 menE Clavibacter michiganensis subsp. michiganensis NCPPB 382 O-succinylbenzoate--CoA ligase YP_001221317.1 659612 D 443906 CDS YP_001221318.1 148271757 5175618 complement(660845..661828) 1 NC_009480.1 putative quinone oxidoreductase (NADPH:quinone reductase) (ZP_00137648.1| hypothetical protein Paer021788 [Pseudomonas aeruginosa UCBPP-PA14]; NP_721489.1| putative oxidoreductase [Streptococcus mutans UA159]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative quinone reductase 661828 5175618 CMM_0578 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative quinone reductase YP_001221318.1 660845 R 443906 CDS YP_001221319.1 148271758 5173076 complement(661825..662256) 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_627620.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_800796.1| putative transcriptional regulator [Vibrio parahaemolyticus RIMD 2210633]). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator 662256 5173076 CMM_0579 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221319.1 661825 R 443906 CDS YP_001221320.1 148271759 5173047 662376..662798 1 NC_009480.1 putative ester cyclase (XP_386716.1| hypothetical protein FG06540.1 [Gibberella zeae PH-1]; NP_825174.1| hypothetical protein SAV3997 [Streptomyces avermitilis MA-4680]; ZP_00227684.1| COG5485: Predicted ester cyclase [Kineococcus radiotolerans SRS30216]).; hypothetical protein 662798 5173047 CMM_0580 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221320.1 662376 D 443906 CDS YP_001221321.1 148271760 5173099 complement(662903..663076) 1 NC_009480.1 hypothetical protein (ZP_00161537.1| COG3237: Uncharacterized protein conserved in bacteria [Anabaena variabilis ATCC 29413]); hypothetical protein 663076 5173099 CMM_0581 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221321.1 662903 R 443906 CDS YP_001221322.1 148271761 5173057 663209..663526 1 NC_009480.1 putative membrane protein (NP_600566.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]).; Hypothetical protein; hypothetical protein 663526 5173057 CMM_0582 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221322.1 663209 D 443906 CDS YP_001221323.1 148271762 5173150 complement(663516..663911) 1 NC_009480.1 putative NTP pyrophosphohydrolase (ZP_00292530.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Thermobifida fusca]; CAG22608.1| hypothetical protein [Photobacterium profundum]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NTP pyrophosphohydrolase 663911 5173150 CMM_0583 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphohydrolase YP_001221323.1 663516 R 443906 CDS YP_001221324.1 148271763 5173112 complement(664071..664676) 1 NC_009480.1 putative acetyltransferase (NP_821878.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]; NP_535242.1| acetyltransferase [Agrobacterium tumefaciens str. C58]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 664676 5173112 CMM_0584 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221324.1 664071 R 443906 CDS YP_001221325.1 148271764 5173164 complement(664690..665268) 1 NC_009480.1 putative acetyltransferase (NP_821878.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]; NP_535242.1| acetyltransferase [Agrobacterium tumefaciens str. C58]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 665268 5173164 CMM_0585 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221325.1 664690 R 443906 CDS YP_001221326.1 148271765 5173135 complement(665325..666644) 1 NC_009480.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 666644 hemA 5173135 hemA Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamyl-tRNA reductase YP_001221326.1 665325 R 443906 CDS YP_001221327.1 148271766 5173709 666749..667876 1 NC_009480.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 667876 hemE 5173709 hemE Clavibacter michiganensis subsp. michiganensis NCPPB 382 uroporphyrinogen decarboxylase YP_001221327.1 666749 D 443906 CDS YP_001221328.1 148271767 5173265 667869..669308 1 NC_009480.1 protoporphyrinogen oxidase (YP_055020.1| putative protoporphyrinogen oxidase, HemY [Propionibacterium acnes KPA171202]; ZP_00294157.1| COG1232: Protoporphyrinogen oxidase [Thermobifida fusca]). InterPro: Protoporphyrinogen oxidase proto_IX_ox: protoporphyrinogen oxidase domain; High confidence in function and specificity; hypothetical protein 669308 hemY 5173265 hemY Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221328.1 667869 D 443906 CDS YP_001221329.1 148271768 5173206 669436..669777 1 NC_009480.1 conserved hypothetical protein (ZP_00226603.1| hypothetical protein Krad06003057 [Kineococcus radiotolerans SRS30216]; ZP_00293622.1| COG1179: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Thermobifida fusca]).; Function unclear; hypothetical protein 669777 5173206 CMM_0589 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221329.1 669436 D 443906 CDS YP_001221330.1 148271769 5173184 669810..670226 1 NC_009480.1 conserved membrane protein (ZP_00226140.1| hypothetical protein Krad06003872 [Kineococcus radiotolerans SRS30216]; NP_827521.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam07332, DUF1469, Protein of unknown function (DUF1469). This family consists of several hypothetical bacterial proteins of around 140 residues in length. Members of the family seem to be found exclusively in Actinomycetes. The function of this family is unknown.; Conserved hypothetical protein; hypothetical protein 670226 5173184 CMM_0590 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221330.1 669810 D 443906 CDS YP_001221331.1 148271770 5173193 670216..670491 1 NC_009480.1 hypothetical protein 670491 5173193 CMM_0591 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221331.1 670216 D 443906 CDS YP_001221332.1 148271771 5173226 670513..672150 1 NC_009480.1 conserved membrane protein (NP_960846.1| hypothetical protein MAP1912 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_822488.1| hypothetical protein SAV1313 [Streptomyces avermitilis MA-4680]).; Conserved hypothetical protein; hypothetical protein 672150 5173226 CMM_0592 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221332.1 670513 D 443906 CDS YP_001221333.1 148271772 5173211 672238..672801 1 NC_009480.1 conserved hypothetical protein (NP_823314.1| hypothetical protein SAV2138 [Streptomyces avermitilis MA-4680]; CAB03711.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). menD: 2-succinyl-6-hydroxy-24-cyclohexad; hypothetical protein 672801 5173211 CMM_0593 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221333.1 672238 D 443906 CDS YP_001221334.1 148271773 5173244 672863..673642 1 NC_009480.1 conserved hypothetical protein (NP_630152.1| conserved hypothetical protein SC1B5.02 [Streptomyces coelicolor A3(2)]; ZP_00294158.1| COG3253: Uncharacterized conserved protein [Thermobifida fusca]). pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyses the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.; hypothetical protein 673642 5173244 CMM_0594 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221334.1 672863 D 443906 CDS YP_001221335.1 148271774 5173261 673642..674892 1 NC_009480.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 674892 hemH 5173261 hemH Clavibacter michiganensis subsp. michiganensis NCPPB 382 ferrochelatase YP_001221335.1 673642 D 443906 CDS YP_001221336.1 148271775 5175406 674889..675875 1 NC_009480.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 675875 hemC 5175406 hemC Clavibacter michiganensis subsp. michiganensis NCPPB 382 porphobilinogen deaminase YP_001221336.1 674889 D 443906 CDS YP_001221337.1 148271776 5175728 675872..676711 1 NC_009480.1 uroporphyrinogen-III synthase (NP_787859.1| uroporphyrinogen-III synthase-like protein [Tropheryma whipplei str. Twist]; CAD48147.1| uroporphyrinogen III synthase [Bacillus megaterium]). pfam02602, HEM4,Uroporphyrinogen-III synthase HemD. InterPro: Uroporphyrinogen III synthase HEM4; High confidence in function and specificity; hypothetical protein 676711 hemD 5175728 hemD Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221337.1 675872 D 443906 CDS YP_001221338.1 148271777 5175384 676708..677688 1 NC_009480.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 677688 hemB 5175384 hemB Clavibacter michiganensis subsp. michiganensis NCPPB 382 delta-aminolevulinic acid dehydratase YP_001221338.1 676708 D 443906 CDS YP_001221339.1 148271778 5175293 677771..679138 1 NC_009480.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 679138 hemL 5175293 hemL Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamate-1-semialdehyde aminotransferase YP_001221339.1 677771 D 443906 CDS YP_001221340.1 148271779 5175493 complement(679197..680018) 1 NC_009480.1 putative DNA/RNA endonuclease (ZP_00227350.1| COG1864: DNA/RNA endonuclease G, NUC1 [Kineococcus radiotolerans SRS30216]; NP_792286.1| DNA/RNA non-specific endonuclease [Pseudomonas syringae pv. tomato str. DC3000]). pfam01223, Endonuclease_NS, DNA/RNA non-specific endonuclease.; Function unclear; DNA/RNA endonuclease 680018 5175493 CMM_0600 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA/RNA endonuclease YP_001221340.1 679197 R 443906 CDS YP_001221341.1 148271780 5173306 complement(680102..680764) 1 NC_009480.1 putative heme oxygenase (decyclizing) (ZP_00292306.1| COG5398: Heme oxygenase [Thermobifida fusca]; NP_827107.1| putative heme oxygenase [Streptomyces avermitilis MA-4680]). cd00232, HemeO, Heme oxygenase catalyzes the rate limiting step in the degradation of heme to bilirubin, it is essential for recycling of iron from heme. Heme is used as a substrate and cofactor for its own degradation to biliverdin, iron,and carbon monoxide. InterPro: Heme oxygenase.; High confidence in function and specificity; Heme oxygenase (decyclizing) 680764 hemO 5173306 hemO Clavibacter michiganensis subsp. michiganensis NCPPB 382 Heme oxygenase (decyclizing) YP_001221341.1 680102 R 443906 CDS YP_001221342.1 148271781 5174132 complement(680840..681232) 1 NC_009480.1 conserved membrane protein (ZP_00226497.1| COG3759: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_602268.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam06993,DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.; Function unclear; hypothetical protein 681232 5174132 CMM_0602 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221342.1 680840 R 443906 CDS YP_001221343.1 148271782 5173272 complement(681317..682342) 1 NC_009480.1 putative Zinc-dependant oxidoreductase/dehydrogenase (NP_601737.1| putative Zn-NADPH:quinone dehydrogenase [Corynebacterium glutamicum ATCC 13032]; ZP_00272074.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Ralstonia metallidurans CH34]). pfam00107, ADH_zinc_N,Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zinc-dependant oxidoreductase 682342 5173272 CMM_0603 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zinc-dependant oxidoreductase YP_001221343.1 681317 R 443906 CDS YP_001221344.1 148271783 5173314 complement(682375..683400) 1 NC_009480.1 6-phosphofructokinase (fructose 6-phosphate 1-phosphotransferase) (ZP_00293787.1| COG0205: 6-phosphofructokinase [Thermobifida fusca]; PFP_AMYME Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (6-phosphofructokinase, pyrophosphate dependent)(Pyrophosphate-dependent 6-phosphofructose-1-kinase)(PPi-dependent phosphofructokinase)). cd00763,Bacterial_PFK, Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate.; Specificity unclear; hypothetical protein 683400 pfkA 5173314 pfkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221344.1 682375 R 443906 CDS YP_001221345.1 148271784 5174902 683439..684146 1 NC_009480.1 kinase of unknown specificity (NP_733512.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00226595.1| COG1072: Panthothenate kinase [Kineococcus radiotolerans SRS30216]). may be Uridine kinase (EC 2.7.1.48) (Uridine monophosphokinase) (Cytidine monophosphokinase) COG0572, Udk, Uridine kinase [Nucleotide transport and metabolism], or Pantothenate kinase (EC 2.7.1.33). pfam00485, PRK, Phosphoribulokinase / Uridine kinase family. InterPro: ATP/GTP-binding site motif A (P-loop); Specificity unclear; putative kinase 684146 5174902 CMM_0605 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative kinase YP_001221345.1 683439 D 443906 CDS YP_001221346.1 148271785 5173298 complement(684157..684657) 1 NC_009480.1 putative general stress protein (NP_637057.1| general stress protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_294870.1| general stress protein 26, putative [Deinococcus radiodurans R1]). pfam01243, Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase.; Function unclear; putative general stress protein 684657 5173298 CMM_0606 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative general stress protein YP_001221346.1 684157 R 443906 CDS YP_001221347.1 148271786 5173328 684723..685688 1 NC_009480.1 putative DNA repair protein, putative DNA glycosylase (CAB07048.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627260.1| conserved hypothetical protein SCE34.20 [Streptomyces coelicolor A3(2)]). pfam00730, HhH-GPD, HhH-GPD superfamily base excision DNA repair protein. This family contains a diverse range of structurally related DNA repair proteins.; Function unclear; putative DNA repair protein 685688 5173328 CMM_0607 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA repair protein YP_001221347.1 684723 D 443906 CDS YP_001221348.1 148271787 5173342 complement(685740..686546) 1 NC_009480.1 Region start changed from 686564 to 686546 (-18 bases); hypothetical protein 686546 5173342 CMM_0608 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221348.1 685740 R 443906 CDS YP_001221349.1 148271788 5173369 686616..687569 1 NC_009480.1 putative aldose-1-epimerase (NP_696523.1| hypothetical protein with possible aldose-1-epimerase domain [Bifidobacterium longum NCC2705]; YP_055725.1| putative aldose-1-epimerase [Propionibacterium acnes KPA171202]). pfam01263, Aldose_epim, Aldose 1-epimerase.; Specificity unclear; putative aldose-1-epimerase 687569 5173369 CMM_0609 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldose-1-epimerase YP_001221349.1 686616 D 443906 CDS YP_001221350.1 148271789 5173383 687668..688135 1 NC_009480.1 conserved hypothetical protein (ZP_00198752.1| COG0346: Lactoylglutathione lyase and related lyases [Kineococcus radiotolerans SRS30216]; ZP_00293658.1| COG0346: Lactoylglutathione lyase and related lyases [Thermobifida fusca]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Family membership; putative glyoxylase family protein 688135 5173383 CMM_0610 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glyoxylase family protein YP_001221350.1 687668 D 443906 CDS YP_001221351.1 148271790 5173400 688242..688700 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_801192.1| transcriptional regulator, MarR family [Vibrio parahaemolyticus RIMD 2210633]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 688700 5173400 CMM_0611 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221351.1 688242 D 443906 CDS YP_001221352.1 148271791 5173428 complement(688722..689468) 1 NC_009480.1 hypothetical protein 689468 5173428 CMM_0612 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221352.1 688722 R 443906 CDS YP_001221353.1 148271792 5173409 complement(689561..691201) 1 NC_009480.1 putative levanase (26-beta-D-fructan fructanohydrolase) (XP_386627.1| hypothetical protein FG06451.1 [Gibberella zeae PH-1]; NP_348398.1| Levanase [Clostridium acetobutylicum ATCC 824]; BAC54106.1| 2,6-beta-D-fructan-6-levanbiohydrolase [Streptomyces exfoliatus]). pfam00251, Glyco_hydro_32, Glycosyl hydrolases family 32. InterPro: Glycoside hydrolase family 32 pfam00251, Glyco_hydro_32, Glycosyl hydrolases family 32.; Specificity unclear; putative levanase/invertase 691201 sacC 5173409 sacC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative levanase/invertase YP_001221353.1 689561 R 443906 CDS YP_001221354.1 148271793 5175412 691469..693034 1 NC_009480.1 putative levansucrase (Beta-D-fructofuranosyl transferase) (BAB72022.1| beta-fructofuranosidase [Arthrobacter sp. K-1]; AAB36606.1| levansucrase precursor [Gluconacetobacter diazotrophicus]). RELEASES FRUCTOOLIGOSACCHARIDES AND LEVAN A HIGH- MOLECULAR-MASS FRUCTOSYL POLYMER FROM SUCROSE. IT ACTS MORE AS A SUCROSE HYDROLASE THAN AS A FRUCTAN POLYMERASE. pfam02435,Glyco_hydro_68, Levansucrase/Invertase. This Pfam family consists of the glycosyl hydrolase 68 family, including several bacterial levansucrase enzymes, and invertase from zymomonas.; High confidence in function and specificity; putative levansucrase 693034 sacB 5175412 sacB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative levansucrase YP_001221354.1 691469 D 443906 CDS YP_001221355.1 148271794 5173947 693118..693771 1 NC_009480.1 hypothetical membrane protein (NP_625282.1| putative integral membrane protein [Streptomyces coelicolor A3(2)], ZP_00057087.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 693771 5173947 CMM_0615 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221355.1 693118 D 443906 CDS YP_001221356.1 148271795 5173468 693943..694707 1 NC_009480.1 conserved hypothetical protein (NP_823510.1| hypothetical protein SAV2334 [Streptomyces avermitilis MA-4680]; ZP_00227010.1| hypothetical protein Krad06002197 [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 694707 5173468 CMM_0616 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221356.1 693943 D 443906 CDS YP_001221357.1 148271796 5173437 694704..695531 1 NC_009480.1 conserved hypothetical protein, putative copper resistance protein (NP_789674.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00059215.1| COG2372: Uncharacterized protein, homolog of Cu resistance protein CopC [Thermobifida fusca]). pfam04234, CopC, Copper resistance protein CopC. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.; Function unclear; hypothetical protein 695531 5173437 CMM_0617 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221357.1 694704 D 443906 CDS YP_001221358.1 148271797 5173511 complement(695606..696508) 1 NC_009480.1 putative transcriptional regulator, LysR-family (NP_599842.1| transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; AAO65784.1| hypothetical DNA binding protein; SCN_3 [Streptomyces cinnamonensis]). pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; LysR family transcriptional regulator 696508 5173511 CMM_0618 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001221358.1 695606 R 443906 CDS YP_001221359.1 148271798 5173448 696681..700331 1 NC_009480.1 bifunctional protein [Includes: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12) (P5C dehydrogenase)] (YP_055334.1| NAD-dependent aldehyde dehydrogenases [Propionibacterium acnes KPA171202]; CAF18667.1| PROLINE DEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE [Corynebacterium glutamicum ATCC 13032]). , pfam01619, Pro_dh, Proline dehydrogenase. ,pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; High confidence in function and specificity; delta-1-pyrroline-5-carboxylate dehydrogenase /proline oxidase 700331 putA 5173448 putA Clavibacter michiganensis subsp. michiganensis NCPPB 382 delta-1-pyrroline-5-carboxylate dehydrogenase /proline oxidase YP_001221359.1 696681 D 443906 CDS YP_001221360.1 148271799 5174664 700353..700484 1 NC_009480.1 hypothetical protein 700484 5174664 CMM_0620 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221360.1 700353 D 443906 CDS YP_001221361.1 148271800 5173537 700481..701185 1 NC_009480.1 hypothetical protein 701185 5173537 CMM_0621 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221361.1 700481 D 443906 CDS YP_001221362.1 148271801 5173496 701209..701787 1 NC_009480.1 putative 4'-phosphopantetheinyl transferase (NP_832074.1| 4'-phosphopantetheinyl transferase [Bacillus cereus ATCC 14579]; NP_824369.1| putative phosphopantetheinyl transferase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative 4'-phosphopantetheinyl transferase 701787 5173496 CMM_0622 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 4'-phosphopantetheinyl transferase YP_001221362.1 701209 D 443906 CDS YP_001221363.1 148271802 5173562 complement(701792..703105) 1 NC_009480.1 putative metalloendopeptidase, family M1 (NP_827808.1| putative metallopeptidase [Streptomyces avermitilis MA-4680]; NP_938746.1| Putative metallopeptidase [Corynebacterium diphtheriae NCTC 13129]). pfam01433, Peptidase_M1, Peptidase family M1. Members of this family are aminopeptidases.; Function unclear; metalloendopeptidase family M1 703105 5173562 CMM_0623 Clavibacter michiganensis subsp. michiganensis NCPPB 382 metalloendopeptidase family M1 YP_001221363.1 701792 R 443906 CDS YP_001221364.1 148271803 5173570 complement(703102..707304) 1 NC_009480.1 non-ribosomal peptide synthase (CAF20734.1| NON-RIBOSOMAL PEPTIDE SYNTHETASE [Corynebacterium glutamicum ATCC 13032]; NP_827809.1| putative non-ribosomal peptide synthetase [Streptomyces avermitilis MA-4680]). domains: pfam00501, AMP-binding, AMP-binding enzyme; pfam00550, PP-binding, Phosphopantetheine attachment site. 2x COG0663,PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.; Specificity unclear; non-ribosomal peptide synthase 707304 npsC 5173570 npsC Clavibacter michiganensis subsp. michiganensis NCPPB 382 non-ribosomal peptide synthase YP_001221364.1 703102 R 443906 CDS YP_001221365.1 148271804 5173739 complement(707376..707744) 1 NC_009480.1 putative transcriptional regulator, GntR family (NP_626001.1| putative gntR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00057983.1| COG1725: Predicted transcriptional regulators [Thermobifida fusca]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; hypothetical protein 707744 5173739 CMM_0625 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221365.1 707376 R 443906 CDS YP_001221366.1 148271805 5173609 707868..708239 1 NC_009480.1 Hypothetical protein; hypothetical protein 708239 5173609 CMM_0626 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221366.1 707868 D 443906 CDS YP_001221367.1 148271806 5174631 709446..716102 1 NC_009480.1 putative cell-wall associated protein (ZP_00230281.1| wall-associated protein, putative [Listeria monocytogenes str. 4b H7858]; NP_977523.1| wall associated protein, putative [Bacillus cereus ATCC 10987]). C-terminal rhs-domain (Aa 1450-2070) ((AAC32486.1| RhsA [Streptomyces clavuligerus]; ZP_00251926.1| COG3209: Rhs family protein [Bacillus anthracis str. A1055]).; Function unclear; hypothetical protein 716102 5174631 CMM_0627 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221367.1 709446 D 443906 CDS YP_001221368.1 148271807 5173623 complement(716740..717177) 1 NC_009480.1 putative transcriptional regulator, AsnC family (CAB02066.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_625510.1| putative AsnC-family regulatory protein [Streptomyces coelicolor A3(2)]). related to leucine-responsive regulatory protein: MEDIATES A GLOBAL RESPONSE TO LEUCINE. EXOGENOUS LEUCINE AFFECTS THE EXPRESSION OF A NUMBER OF DIFFERENT OPERONS; LRP MEDIATES THIS EFFECT FOR AT LEAST SOME OF THESE OPERONS. FOR EXAMPLE IT IS REGULATOR OF THE BRANCHED-CHAIN AMINO ACID TRANSPORT GENES. pfam01037, AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins.; Specificity unclear; AsnC family transcriptional regulator 717177 5173623 CMM_0628 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AsnC family transcriptional regulator YP_001221368.1 716740 R 443906 CDS YP_001221369.1 148271808 5173656 717361..718203 1 NC_009480.1 hypothetical protein 718203 5173656 CMM_0629 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221369.1 717361 D 443906 CDS YP_001221370.1 148271809 5173742 718242..719486 1 NC_009480.1 putative ornithine aminotransferase ( NP_824597.1| putative ornithine aminotransferase [Streptomyces avermitilis MA-4680]; ZP_00058716.1| COG4992: Ornithine/acetylornithine aminotransferase [Thermobifida fusca]). pfam00202, Aminotran_3, Aminotransferase class-III.; High confidence in function and specificity; putative ornithine aminotransferase 719486 rocD 5173742 rocD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ornithine aminotransferase YP_001221370.1 718242 D 443906 CDS YP_001221371.1 148271810 5173010 719607..720104 1 NC_009480.1 hypothetical protein 720104 5173010 CMM_0631 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221371.1 719607 D 443906 CDS YP_001221372.1 148271811 5173674 720135..720782 1 NC_009480.1 hypothetical protein 720782 5173674 CMM_0632 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221372.1 720135 D 443906 CDS YP_001221373.1 148271812 5173764 complement(720800..721792) 1 NC_009480.1 putative permease, DMT family (YP_062089.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_938965.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00892,DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function. InterPro: Integral membrane protein DUF6 2A78: Carboxylate/Amino Acid/Amine Tra; Specificity unclear; permease DMT family 721792 5173764 CMM_0633 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease DMT family YP_001221373.1 720800 R 443906 CDS YP_001221374.1 148271813 5173698 complement(721857..722258) 1 NC_009480.1 hypothetical protein 722258 5173698 CMM_0634 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221374.1 721857 R 443906 CDS YP_001221375.1 148271814 5173822 complement(722346..723230) 1 NC_009480.1 putative NDP-sugar epimerase (ZP_00185910.1| hypothetical protein Rxyl332801 [Rubrobacter xylanophilus DSM 9941]; NP_103218.1| UDP-galactose 4-epimerase [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative NDP-sugar epimerase 723230 5173822 CMM_0635 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NDP-sugar epimerase YP_001221375.1 722346 R 443906 CDS YP_001221376.1 148271815 5173773 complement(723227..723643) 1 NC_009480.1 hypothetical protein 723643 5173773 CMM_0636 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221376.1 723227 R 443906 CDS YP_001221377.1 148271816 5173846 complement(723640..724875) 1 NC_009480.1 putative benzoate transporter, BenE family (NP_386459.1| PUTATIVE MEMBRANE TRANSPORT PROTEIN [Sinorhizobium meliloti 1021]; ZP_00225740.1| COG3135: Uncharacterized protein involved in benzoate metabolism [Kineococcus radiotolerans SRS30216]). pfam03594, BenE,Benzoate membrane transport protein. InterPro: Benzoate membrane transport protein benE: benzoate membrane transport prot MFS transporter, subfamily 14; Specificity unclear; benzoate transport protein BenE family 724875 5173846 CMM_0637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 benzoate transport protein BenE family YP_001221377.1 723640 R 443906 CDS YP_001221378.1 148271817 5173797 725136..726395 1 NC_009480.1 putative membrane metalloendopeptidase, subfamily M23B (YP_062953.1| cell wall binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00098490.1| COG0739: Membrane proteins related to metalloendopeptidases [Desulfitobacterium hafniense]; NP_693412.1| hypothetical protein OB2491 [Oceanobacillus iheyensis HTE831]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M37 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated.; Function unclear; M23 family membrane bound metalloendopeptidase 726395 5173797 CMM_0638 Clavibacter michiganensis subsp. michiganensis NCPPB 382 M23 family membrane bound metalloendopeptidase YP_001221378.1 725136 D 443906 CDS YP_001221379.1 148271818 5173900 726453..727175 1 NC_009480.1 conserved hypothetical protein (ZP_00137144.2| COG2755: Lysophospholipase L1 and related esterases [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00220463.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R1808]).; Family membership; hypothetical protein 727175 5173900 CMM_0639 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221379.1 726453 D 443906 CDS YP_001221380.1 148271819 5173948 727339..727794 1 NC_009480.1 conserved hypothetical prtoein (ZP_00192028.2| COG5637: Predicted integral membrane protein [Kineococcus radiotolerans SRS30216]; NP_821603.1| hypothetical protein SAV428 [Streptomyces avermitilis MA-4680]). surE: stationary-phase survival protein S; hypothetical protein 727794 5173948 CMM_0640 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221380.1 727339 D 443906 CDS YP_001221381.1 148271820 5173977 727797..728033 1 NC_009480.1 hypothetical protein 728033 5173977 CMM_0641 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221381.1 727797 D 443906 CDS YP_001221382.1 148271821 5173963 728165..728962 1 NC_009480.1 putative membrane protein (NP_824620.1| hypothetical protein SAV3443 [Streptomyces avermitilis MA-4680]; ZP_00228318.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]). pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).; hypothetical protein 728962 5173963 CMM_0642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221382.1 728165 D 443906 CDS YP_001221383.1 148271822 5174004 729154..730227 1 NC_009480.1 putative NAD(P)H-dependent oxidoreductase (ZP_00227298.1| COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family [Kineococcus radiotolerans SRS30216]; NP_737709.1| putative NAD(P)H-dependent 2-cyclohexen-1-one reductase [Corynebacterium efficiens YS-314]). pfam00724, Oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase family.; Function unclear; putative oxidoreductase 730227 5174004 CMM_0643 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221383.1 729154 D 443906 CDS YP_001221384.1 148271823 5174026 complement(730274..731011) 1 NC_009480.1 putative two-component system, response regulator (ZP_00058730.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Thermobifida fusca]; NP_630354.1| putative two-component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 731011 5174026 CMM_0644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001221384.1 730274 R 443906 CDS YP_001221385.1 148271824 5174089 complement(731008..732228) 1 NC_009480.1 putative two-component system sensor kinase (ZP_00226573.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_827214.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00058731.1| COG4585: Signal transduction histidine kinase [Thermobifida fusca]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 732228 5174089 CMM_0645 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001221385.1 731008 R 443906 CDS YP_001221386.1 148271825 5174039 complement(732294..732650) 1 NC_009480.1 putative membrane protein (NP_939424.1| Putative integral membrane protein [Corynebacterium diphtheriae]; NP_827987.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; Hypothetical protein; hypothetical protein 732650 5174039 CMM_0646 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221386.1 732294 R 443906 CDS YP_001221387.1 148271826 5174105 complement(732755..733354) 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_959008.1| hypothetical protein MAP0074 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_629094.1| putative regulatory protein [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator 733354 5174105 CMM_0647 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221387.1 732755 R 443906 CDS YP_001221388.1 148271827 5174070 733415..734998 1 NC_009480.1 putative efflux MFS permease (NP_825134.1| putative transport integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00189667.3| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative efflux MFS permease 734998 5174070 CMM_0648 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative efflux MFS permease YP_001221388.1 733415 D 443906 CDS YP_001221389.1 148271828 5174172 735725..736021 1 NC_009480.1 Hypothetical protein; hypothetical protein 736021 5174172 CMM_0649 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221389.1 735725 D 443906 CDS YP_001221390.1 148271829 5174148 complement(736095..737114) 1 NC_009480.1 putative monooxygenase (NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]; ZP_00227515.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase.; Function unclear; putative monooxygenase 737114 5174148 CMM_0650 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001221390.1 736095 R 443906 CDS YP_001221391.1 148271830 5174247 complement(737194..738264) 1 NC_009480.1 putative monooxygenase (NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]; ZP_00227515.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: Bacterial luciferase; Function unclear; putative monooxygenase 738264 5174247 CMM_0651 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001221391.1 737194 R 443906 CDS YP_001221392.1 148271831 5174214 complement(738309..739274) 1 NC_009480.1 putative Zn-dependant quinone oxidoreductase (ZP_00227353.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_215970.1| qor [Mycobacterium tuberculosis H37Rv]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependant quinone oxidoreductase 739274 qorA 5174214 qorA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant quinone oxidoreductase YP_001221392.1 738309 R 443906 CDS YP_001221393.1 148271832 5175534 739395..740333 1 NC_009480.1 Cysteine synthase chloroplast precursor (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (NP_739056.1| putative cysteine synthase [Corynebacterium efficiens YS-314]; NP_903231.1| cysteine synthase [Chromobacterium violaceum ATCC 12472]). pfam00291, PALP,Pyridoxal-phosphate dependent enzyme. InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity; hypothetical protein 740333 cysK 5175534 cysK Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221393.1 739395 D 443906 CDS YP_001221394.1 148271833 5175124 740336..740920 1 NC_009480.1 putative serine O-acetyltransferase (YP_061730.1| serine O-acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_940228.1| serine acetyltransferase [Corynebacterium diphtheriae NCTC 13129]).; High confidence in function and specificity; putative serine O-acetyltransferase 740920 cysE 5175124 cysE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine O-acetyltransferase YP_001221394.1 740336 D 443906 CDS YP_001221395.1 148271834 5174641 740920..741579 1 NC_009480.1 putative RNA methyltransferase (RNA methylase) (YP_063092.1| tRNA/rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293932.1| COG0566: rRNA methylases [Thermobifida fusca]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. rRNA_methyl_2: RNA methyltransferase T.; Specificity unclear; putative RNA methyltransferase 741579 5174641 CMM_0655 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNA methyltransferase YP_001221395.1 740920 D 443906 CDS YP_001221396.1 148271835 5174272 741611..742171 1 NC_009480.1 conserved hypothetical protein (NP_631271.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00229139.1| COG2320: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam04229,UPF0157, Uncharacterised protein family (UPF0157). Also known as GrpB.; Function unclear; hypothetical protein 742171 5174272 CMM_0656 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221396.1 741611 D 443906 CDS YP_001221397.1 148271836 5174299 complement(742168..742569) 1 NC_009480.1 hypothetical protein (NP_626702.1| hypothetical protein SCC24.30c [Streptomyces coelicolor A3(2)]).; hypothetical protein 742569 5174299 CMM_0657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221397.1 742168 R 443906 CDS YP_001221398.1 148271837 5174417 742620..743141 1 NC_009480.1 putative endoribonuclease (NP_733554.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_771770.1| bll5130 [Bradyrhizobium japonicum USDA 110]). pfam01042, Ribonuc_L-PSP, Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis.; Function unclear; putative endoribonuclease L-PSP 743141 5174417 CMM_0658 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endoribonuclease L-PSP YP_001221398.1 742620 D 443906 CDS YP_001221399.1 148271838 5174348 complement(743160..744161) 1 NC_009480.1 putative adenosine deaminase (Adenosine aminohydrolase 3) (NP_826754.1| putative adenosine deaminase [Streptomyces avermitilis MA-4680]; YP_062278.1| adenosine deaminase protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00962, A_deaminase,Adenosine/AMP deaminase. InterPro: Adenosine and AMP deaminase; High confidence in function and specificity; putative adenosine deaminase 744161 addB 5174348 addB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative adenosine deaminase YP_001221399.1 743160 R 443906 CDS YP_001221400.1 148271839 5174055 744239..744547 1 NC_009480.1 hypothetical protein 744547 5174055 CMM_0660 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221400.1 744239 D 443906 CDS YP_001221401.1 148271840 5173243 745338..748628 1 NC_009480.1 conserved hypothetical protein (NP_627580.1| putative large ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00162995.2| COG1413: FOG: HEAT repeat [Anabaena variabilis ATCC 29413]). COG5635,Predicted NTPase (NACHT family) [Signal transduction mechanisms]. pfam05729, NACHT, NACHT domain. This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.; Function unclear; hypothetical protein 748628 5173243 CMM_0661 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221401.1 745338 D 443906 CDS YP_001221402.1 148271841 5174398 complement(748784..749830) 1 NC_009480.1 NADP-dependent alcohol dehydrogenase (ZP_00226305.1| COG1064: Zn-dependent alcohol dehydrogenases [Kineococcus radiotolerans SRS30216]; CAC35017.1| alcohol dehydrogenase, class C [Mycobacterium smegmatis]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; NADP-dependent alcohol dehydrogenase 749830 adhA 5174398 adhA Clavibacter michiganensis subsp. michiganensis NCPPB 382 NADP-dependent alcohol dehydrogenase YP_001221402.1 748784 R 443906 CDS YP_001221403.1 148271842 5175247 749984..751369 1 NC_009480.1 putative carboxylesterase, type B (P37967|PNBA_BACSU Para-nitrobenzyl esterase (PNB carboxy-esterase) (PNBCE); NP_628470.1| putative carboxylesterase [Streptomyces coelicolor A3(2)]). pfam00135, COesterase,Carboxylesterase.; Specificity unclear; putative carboxylesterase, type B 751369 5175247 CMM_0663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxylesterase, type B YP_001221403.1 749984 D 443906 CDS YP_001221404.1 148271843 5174562 complement(751420..751908) 1 NC_009480.1 putative transcriptional regulator, MerR family (BAD30046.1| hypothetical protein [Rhodococcus opacus]; ZP_00084416.1| COG0789: Predicted transcriptional regulators [Pseudomonas fluorescens PfO-1]; NP_890689.1| putative MerR-family transcriptional regulator [Bordetella bronchiseptica RB50]). pfam00376, MerR, MerR family regulatory protein., binding; Specificity unclear; hypothetical protein 751908 SoxR 5174562 SoxR Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221404.1 751420 R 443906 CDS YP_001221405.1 148271844 5174689 752015..752341 1 NC_009480.1 ferredoxin (YP_062518.1| ferredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787703.1| ferredoxin [Tropheryma whipplei str. Twist]; NP_629284.1| ferredoxin [Streptomyces coelicolor A3(2)]). pfam00037, Fer4, 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases.; High confidence in function and specificity; hypothetical protein 752341 fdxA 5174689 fdxA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221405.1 752015 D 443906 CDS YP_001221406.1 148271845 5172953 752338..752832 1 NC_009480.1 putative flavin-dependant reductase (NP_822657.1| putative flavin-dependent reductase [Streptomyces avermitilis MA-4680]; AAC38226.1| NADH-dependent FMN oxydoreductase [Rhodococcus erythropolis]). pfam01613,Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components.; Specificity unclear; putative flavin-dependant reductase 752832 5172953 CMM_0666 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative flavin-dependant reductase YP_001221406.1 752338 D 443906 CDS YP_001221407.1 148271846 5174477 complement(752869..754794) 1 NC_009480.1 putative secreted phosphoesterase (NP_631671.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00199472.2| COG1409: Predicted phosphohydrolases [Kineococcus radiotolerans SRS30216]; AAO54034.1| Ser/Thr protein phosphatase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00149,Metallophos, Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases.; Function unclear; putative secreted phosphoesterase 754794 5174477 CMM_0667 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted phosphoesterase YP_001221407.1 752869 R 443906 CDS YP_001221408.1 148271847 5174612 755391..756011 1 NC_009480.1 conserved hypothetical protein, putative phosphohydrolase (AAN85489.1| putative cyanamide hydratase [Streptomyces atroolivaceus]; ZP_00170298.2| COG1418: Predicted HD superfamily hydrolase [Ralstonia eutropha JMP134]). pfam01966, HD, HD domain. HD domains are metal dependent phosphohydrolases.; Function unclear; putative phosphohydrolase 756011 5174612 CMM_0668 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphohydrolase YP_001221408.1 755391 D 443906 CDS YP_001221409.1 148271848 5174533 756008..756292 1 NC_009480.1 hypothetical protein 756292 5174533 CMM_0669 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221409.1 756008 D 443906 CDS YP_001221410.1 148271849 5174620 complement(756289..756963) 1 NC_009480.1 hypothetical protein 756963 5174620 CMM_0670 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221410.1 756289 R 443906 CDS YP_001221411.1 148271850 5174654 complement(757050..759155) 1 NC_009480.1 conserved membrane protein (YP_063090.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827281.1| putative membrane protein [Streptomyces avermitilis MA-4680]; NP_939709.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). weak similarities to: pfam01061, ABC2_membrane, ABC-2 type transporter; and pfam00015, MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain. This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.; Function unclear; hypothetical protein 759155 5174654 CMM_0671 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221411.1 757050 R 443906 CDS YP_001221412.1 148271851 5174821 complement(759152..759820) 1 NC_009480.1 hypothetical protein with ATPase domain (CAF21648.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00225487.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 759820 5174821 CMM_0672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221412.1 759152 R 443906 CDS YP_001221413.1 148271852 5174701 complement(759817..760500) 1 NC_009480.1 putative transcriptional regulator, TetR-family (YP_063089.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_823990.1| hypothetical protein SAV2814 [Streptomyces avermitilis MA-4680]; NP_768856.1| transcriptional regulatory protein [Bradyrhizobium japonicum]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 760500 5174701 CMM_0673 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221413.1 759817 R 443906 CDS YP_001221414.1 148271853 5174941 complement(760594..761907) 1 NC_009480.1 putative transcriptional regulator, AraC family (NP_519953.1| PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000]; NP_962164.1| hypothetical protein MAP3230c [Mycobacterium avium subsp. paratuberculosis str. k10]). smart00342, HTH_ARAC,helix_turn_helix, arabinose operon control protein. COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Specificity unclear; AraC family transcriptional regulator 761907 5174941 CMM_0674 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AraC family transcriptional regulator YP_001221414.1 760594 R 443906 CDS YP_001221415.1 148271854 5174759 762248..762451 1 NC_009480.1 Hypothetical protein; hypothetical protein 762451 5174759 CMM_0675 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221415.1 762248 D 443906 CDS YP_001221416.1 148271855 5175043 complement(762473..765496) 1 NC_009480.1 putative dsDNA exonuclease subunit (NP_828232.1| putative exonuclease [Streptomyces avermitilis MA-4680]; AE1643 ATP-dependent dsDNA exonuclease SbcC homolog sbcC [imported] -Listeria innocua (strain Clip11262)). SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity (By similarity).; High confidence in function and specificity; putative exonuclease 765496 sbcC 5175043 sbcC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative exonuclease YP_001221416.1 762473 R 443906 CDS YP_001221417.1 148271856 5175716 complement(765496..766662) 1 NC_009480.1 putative dsDNA exonuclease subunit (NP_625587.1| putative exonuclease [Streptomyces coelicolor A3(2)]; NP_800533.1| putative exonuclease SbcD [Vibrio parahaemolyticus RIMD 2210633]). SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3->5 double strand exonuclease that can open hairpins. It also has a 5 single-strand endonuclease activity. InterPro: DNA repair exonuclease sbcd: exonuclease SbcD; High confidence in function and specificity; putative dsDNA exonuclease subunit 766662 sbcD 5175716 sbcD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dsDNA exonuclease subunit YP_001221417.1 765496 R 443906 CDS YP_001221418.1 148271857 5175910 766983..769637 1 NC_009480.1 putative serine/threonine-protein kinase (NP_630756.1| putative serine/threonine protein kinase [Streptomyces coelicolor A3(2)]; NP_345802.1| conserved hypothetical protein [Streptococcus pneumoniae TIGR4]). pfam00069, Pkinase, Protein kinase domain. smart00220,S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily.; Function unclear; putative serine/threonine-protein kinase 769637 pknC 5175910 pknC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine-protein kinase YP_001221418.1 766983 D 443906 CDS YP_001221419.1 148271858 5173559 769707..770345 1 NC_009480.1 putative acetyltransferase (NP_979782.1| acetyltransferase, GNAT family [Bacillus cereus ATCC 10987]; ZP_00200227.1| COG1670: Acetyltransferases,including N-acetylases of ribosomal proteins [Rubrobacter xylanophilus DSM 9941]).; Function unclear; hypothetical protein 770345 5173559 CMM_0679 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221419.1 769707 D 443906 CDS YP_001221420.1 148271859 5174973 770342..773032 1 NC_009480.1 putative acyl-CoA ligase/aldehyde dehydrogenase contains two domains: N-terminal: CoA ligase (COG0318,CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II ; pfam00501, AMP-binding, AMP-binding enzyme; ZP_00170177.2| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Ralstonia eutropha JMP134]; ZP_00029907.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Burkholderia fungorum]). C-terminal: Dehydrogenase (COG1012, PutA, NAD-dependent aldehyde dehydrogenases; CAC38029.1| aldehyde dehydrogenase [Alcanivorax borkumensis]; ZP_00080991.1| COG1012: NAD-dependent aldehyde dehydrogenases [Geobacter metallireducens]).; Specificity unclear; putative acyl-CoA ligase/aldehyde dehydrogenase 773032 5174973 CMM_0680 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA ligase/aldehyde dehydrogenase YP_001221420.1 770342 D 443906 CDS YP_001221421.1 148271860 5175065 773029..774276 1 NC_009480.1 3-oxoacyl-[acyl-carrier-protein] synthase (Beta-ketoacyl-ACP synthase) (ZP_00331147.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Moorella thermoacetica ATCC 39073]; ZP_00289321.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Magnetococcus sp. MC-1])., ,CATALYZES THE CONDENSATION REACTION OF FATTY ACID SYNTHESIS BY THE ADDITION TO AN ACYL ACCEPTOR OF TWO CARBONS FROM MALONYL-ACP. HAS A PREFERENCE FOR SHORT CHAIN ACID SUBSTRATES., , pfam00109, ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain. pfam02801, Ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain. fabH: 3-oxoacyl-(acyl-carrier-protein); High confidence in function and specificity; 3-oxoacyl-[acyl-carrier-protein] synthase 774276 fabB 5175065 fabB Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-oxoacyl-[acyl-carrier-protein] synthase YP_001221421.1 773029 D 443906 CDS YP_001221422.1 148271861 5175974 774273..775922 1 NC_009480.1 putative acetolactate synthase large subunit (Acetohydroxy-acid synthase large subunit) (YP_052316.1| acetolactate synthase isozyme II large subunit [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_931847.1| acetolactate synthase isozyme II large subunit (AHAS-II) (acetohydroxy-acid synthase II large subunit) (ALS-II)[Photorhabdus luminescens subsp. laumondii TTO1]. pfam02776, TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. pfam00205, TPP_enzyme_M,Thiamine pyrophosphate enzyme, central domain. pfam02775,TPP_enzyme_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.; High confidence in function and specificity; putative acetolactate synthase 775922 ilvG 5175974 ilvG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetolactate synthase YP_001221422.1 774273 D 443906 CDS YP_001221423.1 148271862 5175064 775919..776554 1 NC_009480.1 putative pantothenate metabolism flavoprotein (|AAD21550.1| pantothenate metabolism flavoprotein [Zymomonas mobilis]; ZP_00318608.1| COG0452: Phosphopantothenoylcysteine synthetase/decarboxylase [Oenococcus oeni PSU-1]). pfam02441, Flavoprotein,Flavoprotein. This family contains diverse flavoprotein enzymes.; Function unclear; putative pantothenate metabolism flavoprotein 776554 coaBC 5175064 coaBC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pantothenate metabolism flavoprotein YP_001221423.1 775919 D 443906 CDS YP_001221424.1 148271863 5173752 776547..777245 1 NC_009480.1 putative antimicrobial peptide ABC transporter, ATP-binding protein (NP_815381.1| ABC transporter, ATP-binding protein [Enterococcus faecalis V583]; ZP_00283781.1| COG1136: ABC-type antimicrobial peptide transport system,ATPase component [Burkholderia fungorum LB400]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; peptide ABC transporter ATP-binding protein 777245 5173752 CMM_0684 Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptide ABC transporter ATP-binding protein YP_001221424.1 776547 D 443906 CDS YP_001221425.1 148271864 5174986 777242..778471 1 NC_009480.1 putative antimicrobial peptide ABC transporter,permease component (NP_815380.1| permease protein,putative [Enterococcus faecalis V583]; ZP_00227187.1| COG0577: ABC-type antimicrobial peptide transport system,permease component [Kineococcus radiotolerans SRS30216]).; Specificity unclear; peptide ABC transporter permease 778471 5174986 CMM_0685 Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptide ABC transporter permease YP_001221425.1 777242 D 443906 CDS YP_001221426.1 148271865 5175097 778696..779385 1 NC_009480.1 hypothetical membrane protein (NP_960625.1| hypothetical protein MAP1691c [Mycobacterium avium subsp. paratuberculosis str. k10]; CAF19632.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). only very weak similarity to: pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region.; hypothetical protein 779385 5175097 CMM_0686 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221426.1 778696 D 443906 CDS YP_001221427.1 148271866 5175144 complement(779420..780259) 1 NC_009480.1 putative short-chain alcohol oxidoreductase (NP_103147.1| oxidoreductase of short-chain [Mesorhizobium loti MAFF303099]; ZP_00227341.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain dehydrogenase 780259 5175144 CMM_0687 Clavibacter michiganensis subsp. michiganensis NCPPB 382 short chain dehydrogenase YP_001221427.1 779420 R 443906 CDS YP_001221428.1 148271867 5175193 780416..780892 1 NC_009480.1 conserved hypothetical protein (NP_825702.1| hypothetical protein SAV4525 [Streptomyces avermitilis MA-4680]; NP_962798.1| hypothetical protein MAP3864 [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 780892 5175193 CMM_0688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221428.1 780416 D 443906 CDS YP_001221429.1 148271868 5175178 780975..782264 1 NC_009480.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 782264 purA 5175178 purA Clavibacter michiganensis subsp. michiganensis NCPPB 382 adenylosuccinate synthetase YP_001221429.1 780975 D 443906 CDS YP_001221430.1 148271869 5174853 782357..782485 1 NC_009480.1 hypothetical protein 782485 5174853 CMM_0690 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221430.1 782357 D 443906 CDS YP_001221431.1 148271870 5175283 complement(782498..782950) 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_631735.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; CAA98363.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 782950 5175283 CMM_0691 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221431.1 782498 R 443906 CDS YP_001221432.1 148271871 5175351 783012..783380 1 NC_009480.1 conserved hypothetical protein (NP_631734.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_532221.1| glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein [Agrobacterium tumefaciens str. C58]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily. InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 783380 5175351 CMM_0692 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221432.1 783012 D 443906 CDS YP_001221433.1 148271872 5174910 783456..784205 1 NC_009480.1 hypothetical protein 784205 5174910 CMM_0693 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221433.1 783456 D 443906 CDS YP_001221434.1 148271873 5175386 complement(784209..784745) 1 NC_009480.1 putative ATP/GTP binding protein (NP_625858.1| ATP/GTP binding protein [Streptomyces coelicolor A3(2)]; NP_814788.1| tunicamycin resistance protein, putative [Enterococcus faecalis V583]).; Conserved hypothetical protein; hypothetical protein 784745 5175386 CMM_0694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221434.1 784209 R 443906 CDS YP_001221435.1 148271874 5175027 784899..785327 1 NC_009480.1 conserved hypothetical protein (NP_738977.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_903029.1| conserved hypothetical protein [Chromobacterium violaceum ATCC 12472]). pfam04940, BLUF,Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein.; hypothetical protein 785327 5175027 CMM_0695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221435.1 784899 D 443906 CDS YP_001221436.1 148271875 5174788 complement(785365..786303) 1 NC_009480.1 putative hydrolase (NP_824275.1| putative hydrolase [Streptomyces avermitilis MA-4680]; ZP_00057512.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Thermobifida fusca]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 786303 5174788 CMM_0696 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221436.1 785365 R 443906 CDS YP_001221437.1 148271876 5175339 complement(786349..786603) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (NP_656871.1| HTH_XRE, Helix-turn-helix XRE-family like proteins [Bacillus anthracis A2012]; ZP_00035555.2| hypothetical protein Efae020552 [Enterococcus faecium]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif; Specificity unclear; Cro/CI family transcriptional regulator 786603 5175339 CMM_0697 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001221437.1 786349 R 443906 CDS YP_001221438.1 148271877 5173785 complement(786623..787300) 1 NC_009480.1 hypothetical protein 787300 5173785 CMM_0698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221438.1 786623 R 443906 CDS YP_001221439.1 148271878 5175826 complement(787367..788857) 1 NC_009480.1 two component system, sensor kinase (NP_960156.1| hypothetical protein MAP1222 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_951511.1| sensor histidine kinase [Geobacter sulfurreducens PCA]; NP_739103.1| putative sensor kinase [Corynebacterium efficiens YS-314]). pfam00672, HAMP, HAMP domain. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Function unclear; two component system, sensor kinase 788857 5175826 CMM_0699 Clavibacter michiganensis subsp. michiganensis NCPPB 382 two component system, sensor kinase YP_001221439.1 787367 R 443906 CDS YP_001221440.1 148271879 5174623 complement(788854..789522) 1 NC_009480.1 putative two-component system response regulator (NP_960155.1| hypothetical protein MAP1221 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00225501.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Function unclear; putative two-component system response regulator 789522 5174623 CMM_0700 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001221440.1 788854 R 443906 CDS YP_001221441.1 148271880 5175953 789670..790368 1 NC_009480.1 hypothetical protein 790368 5175953 CMM_0701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221441.1 789670 D 443906 CDS YP_001221442.1 148271881 5175784 790440..791081 1 NC_009480.1 putative acetyltransferase (AAC03422.1| unknown [Myxococcus xanthus]; NP_711398.1| probable Acetyltransferase, GNAT family protein [Leptospira interrogans serovar lai str. 56601]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 791081 5175784 CMM_0702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221442.1 790440 D 443906 CDS YP_001221443.1 148271882 5175226 complement(791116..791481) 1 NC_009480.1 hypothetical protein 791481 5175226 CMM_0703 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221443.1 791116 R 443906 CDS YP_001221444.1 148271883 5174814 complement(791849..792331) 1 NC_009480.1 hypothetical protein 792331 5174814 CMM_0704 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221444.1 791849 R 443906 CDS YP_001221445.1 148271884 5175960 792796..793188 1 NC_009480.1 conserved hypothetical protein (NP_243026.1| BH2160 unknown conserved protein [Bacillus halodurans]; NP_691431.1| hypothetical protein OB0510 [Oceanobacillus iheyensis HTE831]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 793188 5175960 CMM_0705 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221445.1 792796 D 443906 CDS YP_001221446.1 148271885 5175840 793298..795367 1 NC_009480.1 putative beta lactamase/penicillin-binding protein (NP_832928.1| Penicillin-binding protein [Bacillus cereus ATCC 14579]; NP_335363.1| penicillin-binding protein 4 [Mycobacterium tuberculosis CDC1551]). pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and pfam00768 D-alanyl-D-alanine carboxypeptidase.; Function unclear; putative beta lactamase/penicillin-binding protein 795367 pbpB 5175840 pbpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta lactamase/penicillin-binding protein YP_001221446.1 793298 D 443906 CDS YP_001221447.1 148271886 5175491 795421..796800 1 NC_009480.1 putative two-component system, sensor kinase (NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]; ZP_00294209.1| COG4585: Signal transduction histidine kinase [Thermobifida fusca]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase- DNA gyrase B- phytochrome-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 796800 5175491 CMM_0707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001221447.1 795421 D 443906 CDS YP_001221448.1 148271887 5175931 796797..797477 1 NC_009480.1 putative two-component system response regulator (ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_625364.1| putative two component system response regulator [Streptomyces coelicolor A3(2)]). pfam00072, Response_reg,Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 797477 5175931 CMM_0708 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001221448.1 796797 D 443906 CDS YP_001221449.1 148271888 5175260 797660..798079 1 NC_009480.1 stress-induced protein, putative organic hydroperoxide resistance protein (CNP_599276.2| stress-induced protein [Corynebacterium glutamicum ATCC 13032]; YP_055293.1| stress-induced protein [Propionibacterium acnes KPA171202]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; Function unclear; stress-induced protein, putative organic hydroperoxide resistance protein 798079 5175260 CMM_0709 Clavibacter michiganensis subsp. michiganensis NCPPB 382 stress-induced protein, putative organic hydroperoxide resistance protein YP_001221449.1 797660 D 443906 CDS YP_001221450.1 148271889 5175132 798162..798545 1 NC_009480.1 putative chorismate mutase (YP_063084.1| chorismate mutase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626280.1| putative chorismate mutase [Streptomyces coelicolor A3(2)]). pfam01817, Chorismate_mut, Chorismate mutase. InterPro: Chorismate mutase; High confidence in function and specificity; hypothetical protein 798545 tyrA 5175132 tyrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221450.1 798162 D 443906 CDS YP_001221451.1 148271890 5173898 complement(798577..799560) 1 NC_009480.1 conserved hypothetical protein (ZP_00189995.2| COG0189: Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Kineococcus radiotolerans SRS30216]; NP_860745.1| conserved hypothetical protein [Helicobacter hepaticus ATCC 51449]). rimK_fam: S6 modification enzyme RimK fa; hypothetical protein 799560 5173898 CMM_0711 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221451.1 798577 R 443906 CDS YP_001221452.1 148271891 5175321 complement(799650..800480) 1 NC_009480.1 conserved hypothetical protein (NP_822654.1| hypothetical protein [Streptomyces avermitilis MA-4680]; NP_691380.1| hypothetical protein OB0459 [Oceanobacillus iheyensis HTE831]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Family membership; hypothetical protein 800480 5175321 CMM_0712 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221452.1 799650 R 443906 CDS YP_001221453.1 148271892 5175783 complement(800539..801126) 1 NC_009480.1 conserved hypothetical protein (CAF18943.1| putative secreted protein [Corynebacterium glutamicum ATCC 13032]; NP_662037.1| conserved hypothetical protein [Chlorobium tepidum TLS]).; Function unclear; hypothetical protein 801126 5175783 CMM_0713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221453.1 800539 R 443906 CDS YP_001221454.1 148271893 5175961 complement(801284..803158) 1 NC_009480.1 hypothetical protein (ZP_00120551.1| hypothetical protein [Bifidobacterium longum DJO10A]; ZP_00199275.1| hypothetical protein Krad06001109 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 803158 5175961 CMM_0714 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221454.1 801284 R 443906 CDS YP_001221455.1 148271894 5175364 complement(803155..804867) 1 NC_009480.1 conserved membrane protein, putative polysaccharide polymerase (only weak similarities: AAC45844.1| putative O-antigen polymerase [Escherichia coli]) may be involved in EPS biosynthesis; Hypothetical protein; membrane protein, putative polysaccharide polymerase 804867 wzy2 5175364 wzy2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative polysaccharide polymerase YP_001221455.1 803155 R 443906 CDS YP_001221456.1 148271895 5174066 complement(804846..805895) 1 NC_009480.1 putative pyruvyl-transferase (NP_830681.1| putative pyruvyl- transferase [Bacillus cereus ATCC 14579]; CAB92958.1| putative pyruvyl-transferase [Thermoanaerobacter thermohydrosulfuricus]). pfam04230,PS_pyruv_trans, Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis. weak similarity to: COG2327, WcaK,Uncharacterized conserved protein [Function unknown].; Conserved hypothetical protein; putative pyruvyl-transferase 805895 wcnG 5174066 wcnG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyruvyl-transferase YP_001221456.1 804846 R 443906 CDS YP_001221457.1 148271896 5173200 complement(805892..807082) 1 NC_009480.1 putative membrane protein may be involved in the biosynthesis of EPS. weak similarity to: COG2244, RfbX,Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only], and pfam01943, Polysacc_synt, Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide.; Hypothetical protein; hypothetical protein 807082 wzx2 5173200 wzx2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221457.1 805892 R 443906 CDS YP_001221458.1 148271897 5173994 complement(807079..808125) 1 NC_009480.1 putative mannosyltransferase (ZP_00033687.1| COG0438: Glycosyltransferase [Burkholderia fungorum]; AAF04384.1| WbdB; mannosyl transferase B [Klebsiella pneumoniae]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars; Specificity unclear; putative mannosyltransferase 808125 wcnE 5173994 wcnE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mannosyltransferase YP_001221458.1 807079 R 443906 CDS YP_001221459.1 148271898 5173181 complement(808125..809255) 1 NC_009480.1 putative glycosyltransferase (ZP_00226742.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; NP_924472.1| probable glycosyltransferase [Gloeobacter violaceus]; BAA94399.1| mannosyl transferase [Actinobacillus actinomycetemcomitans]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase 809255 wcnD 5173181 wcnD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221459.1 808125 R 443906 CDS YP_001221460.1 148271899 5173111 complement(809255..810730) 1 NC_009480.1 putative undecaprenyl-phosphate galactosephosphotransferase (ZP_00228118.1| COG2148: Sugar transferases involved in lipopolysaccharide synthesis [Kineococcus radiotolerans SRS30216]; NP_624703.1| putative glycosyl transferase [Streptomyces coelicolor A3(2)]; NP_695455.1| undecaprenyl-phosphate sugar phosphotransferase [Bifidobacterium longum NCC2705]). pfam02397, Bac_transf, Bacterial sugar transferase. InterPro: Bacterial sugar transferase.; High confidence in function and specificity; putative undecaprenyl-phosphate sugar phosphotransferase 810730 wcnC 5173111 wcnC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl-phosphate sugar phosphotransferase YP_001221460.1 809255 R 443906 CDS YP_001221461.1 148271900 5173154 complement(810821..811540) 1 NC_009480.1 putative protein-tyrosine-phosphatase (NP_599596.1| protein-tyrosine-phosphatase [Corynebacterium glutamicum ATCC 13032]; NP_695454.1| hypothetical protein with possible low molecular weight protein-tyrosine-phosphatase domain [Bifidobacterium longum NCC2705]). pfam01451,LMWPc, Low molecular weight phosphotyrosine protein phosphatase.; Specificity unclear; hypothetical protein 811540 wzb 5173154 wzb Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221461.1 810821 R 443906 CDS YP_001221462.1 148271901 5173821 complement(811550..812962) 1 NC_009480.1 putative capsular polysaccharide biosynthesis protein, putative protein tyrosine kinase (CAF19058.1| cell surface polysaccharide biosynthesis / Chain length determinant protein [Corynebacterium glutamicum ATCC 13032]; NP_696399.1| possible Etk-like tyrosine kinase involved in Eps biosynthesis [Bifidobacterium longum NCC2705]). two domains. N-terminal: COG3944, Capsular polysaccharide biosynthesis protein; pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases. C-terminal: COG0489, Mrp, ATPases involved in chromosome partitioning; Function unclear; putative protein tyrosine kinase 812962 wzc 5173821 wzc Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein tyrosine kinase YP_001221462.1 811550 R 443906 CDS YP_001221463.1 148271902 5173802 813177..815450 1 NC_009480.1 putative acyltransferase (ZP_00057849.1| COG1835: Predicted acyltransferases [Thermobifida fusca]; CAF19073.1| PROBABLE LIPOPOLYSACCHARIDE MODIFICATION ACYLTRANS [Corynebacterium glutamicum ATCC 13032]). potentially involved in the biosynthesis of (Exo)polysaccharides. pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes.; Family membership; putative acyltransferase 815450 wcnB 5173802 wcnB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyltransferase YP_001221463.1 813177 D 443906 CDS YP_001221464.1 148271903 5173029 complement(815640..816677) 1 NC_009480.1 putative acyltransferase (NP_626735.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_102483.1| probable lipopolysaccharide modification acyltransferase [Mesorhizobium loti MAFF303099]). pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltransferase 816677 wcnA 5173029 wcnA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound acyltransferase YP_001221464.1 815640 R 443906 CDS YP_001221465.1 148271904 5173033 complement(816769..817479) 1 NC_009480.1 putative esterase (only weak similarities,ZP_00071593.1| COG2755: Lysophospholipase L1 and related esterases [Trichodesmium erythraeum IMS101]; NP_809482.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]). pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Family membership; putative esterase 817479 5173033 CMM_0725 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001221465.1 816769 R 443906 CDS YP_001221466.1 148271905 5173780 complement(817680..818729) 1 NC_009480.1 conserved hypothetical protein (NP_822654.1| hypothetical protein [Streptomyces avermitilis MA-4680]; NP_737707.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Function unclear; hypothetical protein 818729 5173780 CMM_0726 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221466.1 817680 R 443906 CDS YP_001221467.1 148271906 5175852 complement(818980..819783) 1 NC_009480.1 putative dienelactone hydrolase (NP_967924.1| dienelactone hydrolase family protein [Bdellovibrio bacteriovorus HD100]; NP_866914.1| probable dienelactone hydrolase [Pirellula sp. 1]). pfam01738, DLH, Dienelactone hydrolase family. InterPro: Dienelactone hydrolase.; Family membership; putative hydrolase 819783 5175852 CMM_0727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221467.1 818980 R 443906 CDS YP_001221468.1 148271907 5175789 complement(819780..822140) 1 NC_009480.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 822140 purL 5175789 purL Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylformylglycinamidine synthase II YP_001221468.1 819780 R 443906 CDS YP_001221469.1 148271908 5174917 complement(822137..822832) 1 NC_009480.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 822832 purQ 5174917 purQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylformylglycinamidine synthase I YP_001221469.1 822137 R 443906 CDS YP_001221470.1 148271909 5174977 complement(822832..823224) 1 NC_009480.1 putative phosphoribosylformylglycinamidine (FGAM) synthase component (ZP_00197960.1| COG1828: Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Kineococcus radiotolerans SRS30216]; ZP_00292269.1| COG1828: Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component [Thermobifida fusca]). pfam02700, PurC, Phosphoribosylformylglycinamidine (FGAM) synthase. This family forms a component of the de novo purine biosynthesis pathway.; High confidence in function and specificity; putative phosphoribosylformylglycinamidine (FGAM) synthase 823224 purS 5174977 purS Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoribosylformylglycinamidine (FGAM) synthase YP_001221470.1 822832 R 443906 CDS YP_001221471.1 148271910 5175358 complement(823345..824028) 1 NC_009480.1 conserved hypothetical protein, putative isomerase (ZP_00227845.1| COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Kineococcus radiotolerans SRS30216]; AAP42849.1| NanT2 [Streptomyces nanchangensis]; NP_889535.1| hypothetical protein BB2999 [Bordetella bronchiseptica RB50]).; Function unclear; hypothetical protein 824028 5175358 CMM_0731 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221471.1 823345 R 443906 CDS YP_001221472.1 148271911 5175929 824193..825590 1 NC_009480.1 putative MFS permease (ZP_00227844.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; AAP42848.1| NanT1 [Streptomyces nanchangensis]). pfam00083, Sugar_tr, Sugar (and other) transporter. TIGRFAM (TIGR00883): metabolite:proton symporter family protein; Specificity unclear; putative MFS permease 825590 5175929 CMM_0732 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221472.1 824193 D 443906 CDS YP_001221473.1 148271912 5175448 complement(825663..826337) 1 NC_009480.1 putative transcriptional regulator, GntR-family (ZP_00227843.1| COG1802: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_627999.1| putative gntR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00392, GntR,Bacterial regulatory proteins, gntR family.; Specificity unclear; GntR family transcriptional regulator 826337 5175448 CMM_0733 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001221473.1 825663 R 443906 CDS YP_001221474.1 148271913 5175004 826366..827205 1 NC_009480.1 putative amidohydrolase (NP_302587.1| putative hydrolase [Mycobacterium leprae]; ZP_00227842.1| COG0388: Predicted amidohydrolase [Kineococcus radiotolerans SRS30216]). pfam00795, CN_hydrolase, Carbon-nitrogen hydrolase. This family contains hydrolases that break carbon-nitrogen bonds.; Function unclear; putative amidohydrolase 827205 5175004 CMM_0734 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative amidohydrolase YP_001221474.1 826366 D 443906 CDS YP_001221475.1 148271914 5175672 complement(827277..828266) 1 NC_009480.1 putative oxidoreductase (NP_960686.1| hypothetical protein MAP1752c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00107451.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme]). pfam00248,Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 828266 5175672 CMM_0735 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221475.1 827277 R 443906 CDS YP_001221476.1 148271915 5174930 828392..828877 1 NC_009480.1 transcriptional regulator, Fur family (Ferric uptake regulator) (O07724|FUR_MYCTU Ferric uptake regulation protein (Ferric uptake regulator); YP_061416.1| ferric uptake regulator, Fur family [Leifsonia xyli subsp. xyli str. CTCB07]) . may act as a global negative controlling element employing Fe(2+) as a cofactor to bind the operator of the repressed genes (By similarity). pfam01475, FUR, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family.; Specificity unclear; FUR family transcriptional regulator 828877 furA 5174930 furA Clavibacter michiganensis subsp. michiganensis NCPPB 382 FUR family transcriptional regulator YP_001221476.1 828392 D 443906 CDS YP_001221477.1 148271916 5174442 828956..830485 1 NC_009480.1 catalase (YP_061415.1| catalase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294401.1| COG0753: Catalase [Thermobifida fusca]). pfam00199, Catalase,Catalase., , InterPro: Catalase; High confidence in function and specificity; hypothetical protein 830485 katA 5174442 katA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221477.1 828956 D 443906 CDS YP_001221478.1 148271917 5175644 complement(830624..832954) 1 NC_009480.1 hypothetical protein (NP_736862.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_233017.1| SecA-related protein [Vibrio cholerae O1 biovar eltor str. N16961]); hypothetical protein 832954 5175644 CMM_0738 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221478.1 830624 R 443906 CDS YP_001221479.1 148271918 5174740 complement(833418..833921) 1 NC_009480.1 putative acetyltransferase (ZP_00199016.1| hypothetical protein Krad022685 [Kineococcus radiotolerans SRS30216]; NP_825281.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). InterPro: GCN5-related N-acetyltransferase pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Family membership; putative acetyltransferase 833921 5174740 CMM_0739 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221479.1 833418 R 443906 CDS YP_001221480.1 148271919 5173915 complement(833936..834535) 1 NC_009480.1 putative acyltransferase (CAE30321.1| acyltransferase [Mesorhizobium septentrionale]; CAC82838.1| NodA protein [Sinorhizobium sp. ORS1044]).; Hypothetical protein; putative acyltransferase 834535 5173915 CMM_0740 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyltransferase YP_001221480.1 833936 R 443906 CDS YP_001221481.1 148271920 5175701 834599..835756 1 NC_009480.1 conserved membrane protein (CAA17327.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_940438.1| Putative integral membrane protein [Corynebacterium diphtheriae]). ,InterPro: Domain of unknown function DUF20 , pfam01594,UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. It is not clear what source suggested that these proteins may be permeases and this information should be treated with caution.; Function unclear; hypothetical protein 835756 5175701 CMM_0741 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221481.1 834599 D 443906 CDS YP_001221482.1 148271921 5175756 835753..836553 1 NC_009480.1 putative membrane protein (NP_738715.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00051056.1| hypothetical protein Magn025090 [Magnetospirillum magnetotacticum]). pfam06724, DUF1206,Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.; putative integral membrane protein 836553 5175756 CMM_0742 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative integral membrane protein YP_001221482.1 835753 D 443906 CDS YP_001221483.1 148271922 5175254 836550..837290 1 NC_009480.1 conserved hypothetical protein, putative epimerase (CAB09457.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_827106.1| hypothetical protein SAV5929 [Streptomyces avermitilis MA-4680]). InterPro: Phenazine biosynthesis PhzC/PhzF protein pfam02567, PhzC-PhzF, Phenazine biosynthesis-like protein. PhzF_family: phenazine biosynthesis pro; Function unclear; hypothetical protein 837290 5175254 CMM_0743 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221483.1 836550 D 443906 CDS YP_001221484.1 148271923 5175378 complement(837317..838630) 1 NC_009480.1 conserved membrane protein (NP_736814.1| putative transport protein [Corynebacterium efficiens YS-314]; ZP_00121591.2| COG1253: Hemolysins and related proteins containing CBS domains [Bifidobacterium longum DJO10A]). ,pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. , pfam00571,CBS, CBS domain. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. (twice). pfam03471,CorC_HlyC, Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters. This domain is also found in CorC that is involved in Magnesium and cobalt efflux. The function of this domain is uncertain but might be involved in modulating transport of ion substrates.; Family membership; hypothetical protein 838630 5175378 CMM_0744 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221484.1 837317 R 443906 CDS YP_001221485.1 148271924 5175561 838844..839251 1 NC_009480.1 Hypothetical protein; hypothetical protein 839251 5175561 CMM_0745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221485.1 838844 D 443906 CDS YP_001221486.1 148271925 5173124 complement(839279..839833) 1 NC_009480.1 putative phosphoribulokinase (Phosphopentokinase) (P37101|KPPR_SYNY3 Phosphoribulokinase (Phosphopentokinase) (PRK); ZP_00109191.1| COG0572: Uridine kinase [Nostoc punctiforme]). pfam00485, PRK,Phosphoribulokinase / Uridine kinase family.; Specificity unclear; putative phosphoribulokinase 839833 prkA 5173124 prkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoribulokinase YP_001221486.1 839279 R 443906 CDS YP_001221487.1 148271926 5175163 complement(839902..840855) 1 NC_009480.1 putative dioxygenase (ZP_00226029.1| COG3485: Protocatechuate 3,4-dioxygenase beta subunit [Kineococcus radiotolerans SRS30216]; CAF18808.1| 3,4-dioxygenase beta subunit [Corynebacterium glutamicum ATCC 13032]).,pfam00775, Dioxygenase_C, Dioxygenase.; Specificity unclear; putative dioxygenase 840855 5175163 CMM_0747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dioxygenase YP_001221487.1 839902 R 443906 CDS YP_001221488.1 148271927 5175410 complement(840974..842203) 1 NC_009480.1 putative monooxygenase (NP_641998.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]; NP_624584.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]).,pfam01360, Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD., InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase).; Specificity unclear; putative monooxygenase 842203 5175410 CMM_0748 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001221488.1 840974 R 443906 CDS YP_001221489.1 148271928 5175564 842313..842807 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_625140.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; CAF19334.1| transcriptional regulator, MarR family [Corynebacterium glutamicum ATCC 13032]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 842807 5175564 CMM_0749 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221489.1 842313 D 443906 CDS YP_001221490.1 148271929 5175156 complement(842826..843623) 1 NC_009480.1 putative glycosyl transferase (NP_792926.1| glycosyl transferase, group 2 family protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_745399.1| glycosyl transferase, group 2 family protein [Pseudomonas putida KT2440]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 843623 5175156 CMM_0750 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221490.1 842826 R 443906 CDS YP_001221491.1 148271930 5174563 complement(843620..846349) 1 NC_009480.1 conserved hypothetical protein, acyl-CoA dehydrogenase/methyltransferase multidomain protein: N-terminal (AA 150-350) putative acyl-CoA dehydrogenase (COG1960, CaiA, Acyl-CoA dehydrogenases) (NP_962172.1| hypothetical protein MAP3238 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_745402.1| acyl-CoA dehydrogenase-related protein [Pseudomonas putida KT2440]); AA 475-700 COG2120, COG2120, Uncharacterized proteins, LmbE homologs (NP_962173.1| hypothetical protein MAP3239 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00265336.1| COG2120: Uncharacterized proteins,LmbE homologs [Pseudomonas fluorescens PfO-1]); C-terminal (AA 720-850) putative methyltransferase (pfam05401, NodS,Nodulation protein S (NodS)(ZP_00284505.1| COG0500: SAM-dependent methyltransferases [Burkholderia fungorum LB400]; NP_745400.1| methyltransferase, putative [Pseudomonas putida KT2440]).; Function unclear; acyl-CoA dehydrogenase/methyltransferase 846349 5174563 CMM_0751 Clavibacter michiganensis subsp. michiganensis NCPPB 382 acyl-CoA dehydrogenase/methyltransferase YP_001221491.1 843620 R 443906 CDS YP_001221492.1 148271931 5174991 846449..846667 1 NC_009480.1 putative hypothetical protein; hypothetical protein 846667 5174991 CMM_0752 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221492.1 846449 D 443906 CDS YP_001221493.1 148271932 5175530 complement(846755..847675) 1 NC_009480.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 847675 purC 5175530 purC Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_001221493.1 846755 R 443906 CDS YP_001221494.1 148271933 5175892 complement(847672..848922) 1 NC_009480.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 848922 purD 5175892 purD Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylamine--glycine ligase YP_001221494.1 847672 R 443906 CDS YP_001221495.1 148271934 5174455 849311..849691 1 NC_009480.1 conserved hypothetical protein (AAT89946.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225567.1| hypothetical protein Krad06004784 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 849691 5174455 CMM_0755 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221495.1 849311 D 443906 CDS YP_001221496.1 148271935 5174899 849751..850059 1 NC_009480.1 putative membrane protein (YP_063050.1| hypothetical protein Lxx22770 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 850059 5174899 CMM_0756 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221496.1 849751 D 443906 CDS YP_001221497.1 148271936 5175706 complement(850126..851586) 1 NC_009480.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 851586 purF 5175706 purF Clavibacter michiganensis subsp. michiganensis NCPPB 382 amidophosphoribosyltransferase YP_001221497.1 850126 R 443906 CDS YP_001221498.1 148271937 5174092 851676..852785 1 NC_009480.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 852785 purM 5174092 purM Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylaminoimidazole synthetase YP_001221498.1 851676 D 443906 CDS YP_001221499.1 148271938 5173132 complement(852922..853131) 1 NC_009480.1 conserved hypothetical protein (AAT89942.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302445.1| conserved hypothetical protein [Mycobacterium leprae]).; hypothetical protein 853131 5173132 CMM_0759 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221499.1 852922 R 443906 CDS YP_001221500.1 148271939 5174687 853341..854471 1 NC_009480.1 putative FAD-dependant monooxygenase/oxidoreductase (YP_063046.1| flavine-dependent monooxygenase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625435.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. InterPro: NAD binding site; Function unclear; putative FAD-dependant oxidoreductase 854471 5174687 CMM_0760 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative FAD-dependant oxidoreductase YP_001221500.1 853341 D 443906 CDS YP_001221501.1 148271940 5174049 complement(854801..856861) 1 NC_009480.1 putative amino acid permease, APC family (AAR90221.1| putative membrane protein [Rhodococcus sp. DK17]; NP_825951.1| putative membrane protein [Streptomyces avermitilis MA-4680]). pfam00324,AA_permease, Amino acid permease. InterPro: Permease for amino acids and related compounds family I.; Specificity unclear; amino acid permease APC family 856861 5174049 CMM_0761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid permease APC family YP_001221501.1 854801 R 443906 CDS YP_001221502.1 148271941 5174817 complement(856950..857615) 1 NC_009480.1 conserved membrane protein (NP_625700.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00057925.1| COG2364: Predicted membrane protein [Thermobifida fusca]). pfam02588, DUF161,Uncharacterized BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C). (twice).; Function unclear; hypothetical protein 857615 5174817 CMM_0762 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221502.1 856950 R 443906 CDS YP_001221503.1 148271942 5174302 857678..859141 1 NC_009480.1 putative transcriptional regulator containing a DNA-binding HTH domain and an aminotransferase domain (ZP_00228006.1| COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Kineococcus radiotolerans SRS30216]; NP_828105.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392,GntR, Bacterial regulatory proteins, gntR family. pfam00155, Aminotran_1_2, Aminotransferase class I and II.; Function unclear; transcriptional regulator 859141 5174302 CMM_0763 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator YP_001221503.1 857678 D 443906 CDS YP_001221504.1 148271943 5174691 859301..860284 1 NC_009480.1 putative extracellular serine protease, glutamyl endopeptidase (ZP_00227464.1| COG3591: V8-like Glu-specific endopeptidase [Kineococcus radiotolerans SRS30216]; NP_297821.1| hypothetical protein [Xylella fastidiosa 9a5c]).; Function unclear; hypothetical protein 860284 ppaF 5174691 ppaF Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221504.1 859301 D 443906 CDS YP_001221505.1 148271944 5174225 860397..862478 1 NC_009480.1 putative glycogen debranching enzyme (ZP_00228190.1| COG1523: Type II secretory pathway,pullulanase PulA and related glycosidases [Kineococcus radiotolerans SRS30216]; YP_061380.1| glycogen debranching enzyme [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycogen debranching enzyme 862478 5174225 CMM_0765 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycogen debranching enzyme YP_001221505.1 860397 D 443906 CDS YP_001221506.1 148271945 5175686 862605..863672 1 NC_009480.1 conserved membrane protein (NP_295927.1| conserved hypothetical protein [Deinococcus radiodurans R1]; NP_281741.1| putative integral membrane protein [Campylobacter jejuni subsp.jejuni NCTC 11168]).; Function unclear; hypothetical protein 863672 5175686 CMM_0766 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221506.1 862605 D 443906 CDS YP_001221507.1 148271946 5175330 complement(863669..864067) 1 NC_009480.1 hypothetical protein (YP_062777.1| hypothetical protein Lxx19520 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 864067 5175330 CMM_0767 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221507.1 863669 R 443906 CDS YP_001221508.1 148271947 5175160 complement(864085..864483) 1 NC_009480.1 hypothetical protein (ZP_00228438.1| COG4338: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00267705.1| COG0117: Pyrimidine deaminase [Rhodospirillum rubrum]; ZP_00328354.1| COG4338: Uncharacterized protein conserved in bacteria [Trichodesmium erythraeum IMS101]). weak similarity to: COG4338, Uncharacterized protein conserved in bacteria [Function unknown].; hypothetical protein 864483 5175160 CMM_0768 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221508.1 864085 R 443906 CDS YP_001221509.1 148271948 5174822 864672..867941 1 NC_009480.1 putative integral membrane efflux protein, RND family (NP_827216.1| putative integral membrane efflux protein [Streptomyces avermitilis MA-4680]; ZP_00330620.1| COG0841: Cation/multidrug efflux pump [Moorella thermoacetica ATCC 39073]). pfam00873, ACR_tran,AcrB/AcrD/AcrF family. Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.; Specificity unclear; RND family mulitdrug efflux protein 867941 5174822 CMM_0769 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RND family mulitdrug efflux protein YP_001221509.1 864672 D 443906 CDS YP_001221510.1 148271949 5173401 869280..870491 1 NC_009480.1 putative RNA helicase (YP_062998.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227011.1| COG0513: Superfamily II DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). 25466,pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent RNA helicase 870491 5173401 CMM_0770 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent RNA helicase YP_001221510.1 869280 D 443906 CDS YP_001221511.1 148271950 5173649 870534..871118 1 NC_009480.1 putative acetyltransferase (ZP_00227685.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; ZP_00086502.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Pseudomonas fluorescens PfO-1]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 871118 5173649 CMM_0771 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221511.1 870534 D 443906 CDS YP_001221512.1 148271951 5175528 871152..871655 1 NC_009480.1 putative acetyltransferase (ZP_00226643.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; NP_828437.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 871655 5175528 CMM_0772 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221512.1 871152 D 443906 CDS YP_001221513.1 148271952 5175105 871708..872181 1 NC_009480.1 Hypothetical protein; hypothetical protein 872181 5175105 CMM_0773 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221513.1 871708 D 443906 CDS YP_001221514.1 148271953 5175673 872320..873297 1 NC_009480.1 putative sugar kinase (BAB97551.1| Sugar kinases,ribokinase family [Corynebacterium glutamicum ATCC 13032]; ZP_00226213.1| COG0524: Sugar kinases, ribokinase family [Kineococcus radiotolerans SRS30216]). pfam00294,PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative sugar kinase 873297 5175673 CMM_0774 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar kinase YP_001221514.1 872320 D 443906 CDS YP_001221515.1 148271954 5174913 873294..874235 1 NC_009480.1 conserved hypothetical protein, putative aldolase (CAF18726.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00226214.1| hypothetical protein Krad06003760 [Kineococcus radiotolerans SRS30216]).; Function unclear; putative aldolase 874235 5174913 CMM_0775 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldolase YP_001221515.1 873294 D 443906 CDS YP_001221516.1 148271955 5174559 874289..875794 1 NC_009480.1 putative NAD-dependent aldehyde dehydrogenase (NP_599412.1| NAD-dependent aldehyde dehydrogenase [Corynebacterium glutamicum ATCC 13032]; ZP_00226521.1| COG1012: NAD-dependent aldehyde dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam00171, Aldedh,Aldehyde dehydrogenase family. InterPro: Aldehyde dehydrogenase family; Specificity unclear; putative NAD-dependent aldehyde dehydrogenase 875794 5174559 CMM_0776 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD-dependent aldehyde dehydrogenase YP_001221516.1 874289 D 443906 CDS YP_001221517.1 148271956 5175236 875854..876780 1 NC_009480.1 conserved hypothetical protein involved in inositol metabolism (CAF18728.1| enzyme involved in inositol metabolism [Corynebacterium glutamicum ATCC 13032]; NP_631041.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam06845, IolB, Myo-inositol catabolism protein IolB. This family consists of several bacterial Myo-inositol catabolism (IolB) proteins.The exact function of IolB is unknown.; High confidence in function and specificity; hypothetical protein 876780 5175236 CMM_0777 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221517.1 875854 D 443906 CDS YP_001221518.1 148271957 5173059 876777..878693 1 NC_009480.1 putative acetolactate synthase (CAF18729.1| PUTATIVE ACETOLACTATE SYNTHASE PROTEIN [Corynebacterium glutamicum ATCC 13032]; ZP_00226216.1| COG3962: Acetolactate synthase [Kineococcus radiotolerans SRS30216]). pfam02776, TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. pfam00205, TPP_enzyme_M, Thiamine pyrophosphate enzyme,central domain. pfam02775, TPP_enzyme_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain. acolac_lg: acetolactate synthase larg; Specificity unclear; putative acetolactate synthase 878693 5173059 CMM_0778 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetolactate synthase YP_001221518.1 876777 D 443906 CDS YP_001221519.1 148271958 5173381 complement(878806..879132) 1 NC_009480.1 hypothetical protein 879132 5173381 CMM_0779 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221519.1 878806 R 443906 CDS YP_001221520.1 148271959 5173074 879560..880537 1 NC_009480.1 putative sugar phosphate isomerase/epimerase (NP_438000.1| HYPOTHETICAL PROTEIN SMb20768 [Sinorhizobium meliloti 1021]; ZP_00228598.1| COG3623: Putative L-xylulose-5-phosphate 3-epimerase [Kineococcus radiotolerans SRS30216]). COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]. hxl6Piso_put: hexulose-6-phosphate is; Specificity unclear; putative sugar phosphate isomerase/epimerase 880537 5173074 CMM_0780 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar phosphate isomerase/epimerase YP_001221520.1 879560 D 443906 CDS YP_001221521.1 148271960 5175715 880534..881502 1 NC_009480.1 putative 3-hydroxyacyl-CoA dehydrogenase (ZP_00228602.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Kineococcus radiotolerans SRS30216]; ZP_00298783.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Geobacter metallireducens GS-15]). pfam02737, 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. pfam00725, 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain.; Specificity unclear; putative 3-hydroxyacyl-CoA dehydrogenase 881502 5175715 CMM_0781 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 3-hydroxyacyl-CoA dehydrogenase YP_001221521.1 880534 D 443906 CDS YP_001221522.1 148271961 5174279 complement(881536..882285) 1 NC_009480.1 putative oxidoreductase (NP_793827.1| oxidoreductase, short-chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; NP_631846.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. TIGR00301: NADP oxidoreductase coenzym; Function unclear; putative oxidoreductase 882285 5174279 CMM_0782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221522.1 881536 R 443906 CDS YP_001221523.1 148271962 5175629 882419..883261 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (ZP_00226903.1| COG1396: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_631845.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 883261 5175629 CMM_0783 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001221523.1 882419 D 443906 CDS YP_001221524.1 148271963 5174318 883362..884003 1 NC_009480.1 Hypothetical protein; hypothetical protein 884003 5174318 CMM_0784 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221524.1 883362 D 443906 CDS YP_001221525.1 148271964 5174001 complement(884011..884700) 1 NC_009480.1 putative transcriptional regulator, GntR family (ZP_00196672.1| hypothetical protein MBNC415202 [Mesorhizobium sp. BNC1]; NP_435388.1| putative GntR-family regulator [Sinorhizobium meliloti 1021]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; GntR family transcriptional regulator 884700 5174001 CMM_0785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001221525.1 884011 R 443906 CDS YP_001221526.1 148271965 5173030 complement(884749..885546) 1 NC_009480.1 putative triosephosphate isomerase (NP_624890.1| putative triosephosphate isomerase [Streptomyces coelicolor A3(2)]; YP_048976.1| putative triosephosphate isomerase [Erwinia carotovora subsp. atroseptica SCRI1043]). , pfam00121, TIM, Triosephosphate isomerase.; High confidence in function and specificity; putative triosephosphate isomerase 885546 tpiB 5173030 tpiB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative triosephosphate isomerase YP_001221526.1 884749 R 443906 CDS YP_001221527.1 148271966 5175792 complement(885551..886012) 1 NC_009480.1 putative ribose 5-phosphate isomerase (NP_624891.1| putative ribose 5-phosphate isomerase [Streptomyces coelicolor A3(2)]; XP_456866.1| unnamed protein product [Debaryomyces hansenii]). , pfam02502, LacAB_rpiB,Ribose/Galactose Isomerase. InterPro: Ribose/Galactose Isomerase.; High confidence in function and specificity; putative ribose 5-phosphate isomerase 886012 rpiB 5175792 rpiB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ribose 5-phosphate isomerase YP_001221527.1 885551 R 443906 CDS YP_001221528.1 148271967 5172945 complement(886062..887798) 1 NC_009480.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 887798 dakA 5172945 dakA Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydroxyacetone kinase YP_001221528.1 886062 R 443906 CDS YP_001221529.1 148271968 5174588 complement(887879..888640) 1 NC_009480.1 putative transcriptional regulator, GntR family (CAF18724.1| Bacterial regulatory proteins, gntR family [Corynebacterium glutamicum ATCC 13032]; NP_823160.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392, GntR,Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator 888640 5174588 CMM_0789 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001221529.1 887879 R 443906 CDS YP_001221530.1 148271969 5173546 complement(888694..889623) 1 NC_009480.1 putative sugar ABC transporter ATP-binding protein (NP_630359.1| probable ABC sugar transport ATP binding protein [Streptomyces coelicolor A3(2)]; ZP_00226220.1| COG1129: ABC-type sugar transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative sugar ABC transporter ATP-binding protein 889623 5173546 CMM_0790 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter ATP-binding protein YP_001221530.1 888694 R 443906 CDS YP_001221531.1 148271970 5172971 complement(889620..890663) 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_631045.1| probable ABC transport protein, membrane component. [Streptomyces coelicolor A3(2)]; ZP_00226219.1| COG1172: Ribose/xylose/arabinose/ galactoside ABC-type transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families); Specificity unclear; putative sugar ABC transporter, permease component 890663 5172971 CMM_0791 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221531.1 889620 R 443906 CDS YP_001221532.1 148271971 5174075 complement(890768..891745) 1 NC_009480.1 putative sugar ABC transporter, solute-binding protein (NP_631044.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00226218.1| COG1879: ABC-type sugar transport system, periplasmic component [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative sugar ABC transporter, solute-binding protein 891745 5174075 CMM_0792 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, solute-binding protein YP_001221532.1 890768 R 443906 CDS YP_001221533.1 148271972 5175140 complement(892001..893008) 1 NC_009480.1 putative myo-inositol dehydrogenase (ZP_00199086.2| COG0673: Predicted dehydrogenases and related proteins [Kineococcus radiotolerans SRS30216]; NP_602254.1| myo-inositol dehydrogenase [Corynebacterium glutamicum ATCC 13032]). pfam01408, GFO_IDH_MocA, Oxidoreductase family,NAD-binding Rossmann fold. This family of enzymes utilise NADP or NAD. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Specificity unclear; putative myo-inositol dehydrogenase 893008 5175140 CMM_0793 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative myo-inositol dehydrogenase YP_001221533.1 892001 R 443906 CDS YP_001221534.1 148271973 5172961 complement(893068..893985) 1 NC_009480.1 putative sugar epimerase (ZP_00200300.1| COG1082: Sugar phosphate isomerases/epimerases [Rubrobacter xylanophilus DSM 9941]; ZP_00092855.1| COG1082: Sugar phosphate isomerases/epimerases [Azotobacter vinelandii]; NP_519368.1| PUTATIVE MYO-INOSITOL CATABOLISM PROTEIN [Ralstonia solanacearum]).; Function unclear; putative sugar epimerase 893985 5172961 CMM_0794 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar epimerase YP_001221534.1 893068 R 443906 CDS YP_001221535.1 148271974 5173256 894292..896427 1 NC_009480.1 putative extracellular nuclease/phosphatase (NP_601790.1| predicted extracellular nuclease [Corynebacterium glutamicum ATCC 13032]; NP_927023.1| hypothetical protein gll4077 [Gloeobacter violaceus]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; Function unclear; putative extracellular nuclease/phosphatase 896427 5173256 CMM_0795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular nuclease/phosphatase YP_001221535.1 894292 D 443906 CDS YP_001221536.1 148271975 5173751 896513..896914 1 NC_009480.1 putative thioredoxin (ZP_00292263.1| COG0526: Thiol-disulfide isomerase and thioredoxins [Thermobifida fusca]; NP_739422.1| putative thioredoxin [Corynebacterium efficiens YS-314]). Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. pfam00085,Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. InterPro: Thioredoxin.; High confidence in function and specificity; putative thioredoxin 896914 trxC 5173751 trxC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001221536.1 896513 D 443906 CDS YP_001221537.1 148271976 5174923 897027..898910 1 NC_009480.1 putative ATP-dependent DNA helicase (YP_062975.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628739.1| putative helicase [Streptomyces coelicolor A3(2)]). pfam00270, DEAD,DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C,Helicase conserved C-terminal domain. pfam00570, HRDC,HRDC domain. The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding.; Specificity unclear; putative ATP-dependent DNA helicase 898910 recQ3 5174923 recQ3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001221537.1 897027 D 443906 CDS YP_001221538.1 148271977 5173345 899312..901318 1 NC_009480.1 conserved hypothetical protein (ZP_00228010.1| COG3533: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_228092.1| hypothetical protein [Thermotoga maritima]).; Function unclear; hypothetical protein 901318 5173345 CMM_0798 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221538.1 899312 D 443906 CDS YP_001221539.1 148271978 5174539 901468..903150 1 NC_009480.1 putative oligopeptide ABC transporter, substrate-binding lipoprotein (NP_629263.1| BldKB, putative ABC transport system lipoprotein [Streptomyces coelicolor A3(2)]; ZP_00294235.1| COG0747: ABC-type dipeptide transport system, periplasmic component [Thermobifida fusca]). This protein is a component of the oligopeptide permease, a binding protein-dependent transport system It binds peptides up small peptides with high affinity. Also required for sporulation and competence. pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative oligopeptide ABC transporter, substrate-binding lipoprotein 903150 bldKB 5174539 bldKB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, substrate-binding lipoprotein YP_001221539.1 901468 D 443906 CDS YP_001221540.1 148271979 5173204 903154..904116 1 NC_009480.1 putative oligopeptide ABC transporter, permease component (ZP_00059564.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; NP_629262.1| BldKA,putative ABC transport system integral membrane protein [Streptomyces coelicolor A3(2)]). Part of the binding-protein-dependent transport system for peptides; probably responsible for the translocation of the substrate across the membrane. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter, permease component 904116 bldKA 5173204 bldKA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001221540.1 903154 D 443906 CDS YP_001221541.1 148271980 5173679 904113..905105 1 NC_009480.1 putative peptide ABC transporter, permease component (ZP_00059566.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; NP_629264.1| BldKC,putative ABC transport system integral membrane protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 905105 bldKC 5173679 bldKC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001221541.1 904113 D 443906 CDS YP_001221542.1 148271981 5174002 905102..905968 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_824329.1| putative ABC transporter intracellular ATPase BldKD [Streptomyces avermitilis MA-4680]; NP_059748.1| moaD [Agrobacterium tumefaciens]). ,, Part of the binding-protein-dependent transport system for peptides. Probably responsible for energy coupling to the transport system., , InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 905968 bldKD 5174002 bldKD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001221542.1 905102 D 443906 CDS YP_001221543.1 148271982 5173804 905965..906903 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_824330.1| putative ABC transporter ATP-binding protein BldKE [Streptomyces avermitilis MA-4680]; NP_244512.1| oligopeptide ABC transporter (ATP-binding protein) [Bacillus halodurans]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 906903 bldKE 5173804 bldKE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001221543.1 905965 D 443906 CDS YP_001221544.1 148271983 5175301 906900..908207 1 NC_009480.1 putative proline iminopeptidase (Prolyl aminopeptidase)(JC4623 prolyl aminopeptidase (EC 3.4.11.5) - Hafnia alvei; NP_696104.1| proline iminopeptidase [Bifidobacterium longum NCC2705]). InterPro: Esterase/lipase/thioesterase family active site pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Specificity unclear; putative prolyl aminopeptidase 908207 pipA 5175301 pipA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative prolyl aminopeptidase YP_001221544.1 906900 D 443906 CDS YP_001221545.1 148271984 5173703 908204..909688 1 NC_009480.1 putative Xaa-Pro aminopeptidase (Aminoacylproline aminopeptidase) (NP_696514.1| Xaa-Pro aminopeptidase I [Bifidobacterium longum NCC2705]; NP_625637.1| Xaa-Pro aminopeptidase II (EC 3.4.11.9) [Streptomyces coelicolor A3(2)]). , pfam05195, AMP_N, Aminopeptidase P, N-terminal domain. , pfam00557, Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative Xaa-Pro aminopeptidase 909688 pepP1 5173703 pepP1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Xaa-Pro aminopeptidase YP_001221545.1 908204 D 443906 CDS YP_001221546.1 148271985 5175056 909706..910419 1 NC_009480.1 putative transcriptional regulator, GntR-family (NP_822905.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_879291.1| putative GntR-family transcriptional regulator [Bordetella pertussis Tohama I]). pfam00392,GntR, Bacterial regulatory proteins, gntR family. This domain comprises the N-terminal HTH-containing region of GntR-like bacterial transcription factors. At the C terminus there is usually an effector-binding/oligomerisation domain.; Specificity unclear; GntR family transcriptional regulator 910419 5175056 CMM_0806 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001221546.1 909706 D 443906 CDS YP_001221547.1 148271986 5173375 910532..911776 1 NC_009480.1 putative secreted D-amino acid oxidase (NP_630387.1| putative secreted oxidoreductase [Streptomyces coelicolor A3(2)]; NP_832586.1| Sarcosine oxidase beta subunit [Bacillus cereus ATCC 14579]). pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases.; Specificity unclear; putative secreted D-amino acid oxidase 911776 5173375 CMM_0807 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted D-amino acid oxidase YP_001221547.1 910532 D 443906 CDS YP_001221548.1 148271987 5173151 911773..912111 1 NC_009480.1 conserved hypothetical protein, putative D-amino acid oxidase subunit (NP_822909.1| hypothetical protein SAV1733 [Streptomyces avermitilis MA-4680]; NP_832589.1| Sarcosine oxidase alpha subunit [Bacillus cereus ATCC 14579]). weak similarity to COG3383, Uncharacterized anaerobic dehydrogenase; hypothetical protein 912111 5173151 CMM_0808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221548.1 911773 D 443906 CDS YP_001221549.1 148271988 5175641 912108..913799 1 NC_009480.1 putative amino acid oxidase (NP_630389.1| putative secreted oxidase [Streptomyces coelicolor A3(2)]; AAQ87569.1| Opine oxidase subunit A [Rhizobium sp. NGR234]; AAC38595.1| hydrogen cyanide synthase HcnB [Pseudomonas fluorescens]) pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues.; Function unclear; putative amino acid oxidase 913799 5175641 CMM_0809 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative amino acid oxidase YP_001221549.1 912108 D 443906 CDS YP_001221550.1 148271989 5173083 913796..914713 1 NC_009480.1 putative dihydrodipicolinate synthase (NP_822907.1| putative dihydrodipicolinate synthase [Streptomyces avermitilis MA-4680]; NP_797714.1| probable dihydrodipicolinate synthetase [Vibrio parahaemolyticus RIMD 2210633]). pfam00701, DHDPS, Dihydrodipicolinate synthetase family. This family has a TIM barrel structure.; High confidence in function and specificity; dihydrodipicolinate synthase 914713 dapX 5173083 dapX Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydrodipicolinate synthase YP_001221550.1 913796 D 443906 CDS YP_001221551.1 148271990 5174858 914721..915722 1 NC_009480.1 putative proline racemase (NP_822906.1| putative proline racemase [Streptomyces avermitilis MA-4680]; NP_845180.1| proline racemase, putative [Bacillus anthracis str. Ames]). pfam05544, Pro_racemase, Proline racemase. This family consists of proline racemase (EC 5.1.1.4) proteins which catalyse the interconversion of L-and D-proline in bacteria.; High confidence in function and specificity; putative proline racemase 915722 5174858 CMM_0811 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proline racemase YP_001221551.1 914721 D 443906 CDS YP_001221552.1 148271991 5173343 915749..917269 1 NC_009480.1 putative aldehyde dehydrogenase (AAR90163.1| putative aldehyde dehydrogenase [Rhodococcus sp. DK17]; NP_827565.1| putative aldehyde dehydrogenase [Streptomyces avermitilis MA-4680]). InterPro: Aldehyde dehydrogenase family pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; Specificity unclear; putative aldehyde dehydrogenase 917269 5173343 CMM_0812 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldehyde dehydrogenase YP_001221552.1 915749 D 443906 CDS YP_001221553.1 148271992 5173105 917535..919640 1 NC_009480.1 putative acyl-CoA oxidase (YP_062974.1| acyl-CoA oxidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058724.1| COG1960: Acyl-CoA dehydrogenases [Thermobifida fusca]). pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain. pfam01756, ACOX,Acyl-CoA oxidase. This is a family of Acyl-CoA oxidases EC:1.3.3.6. Acyl-coA oxidase converts acyl-CoA into trans-2- enoyl-CoA.; Specificity unclear; putative acyl-CoA oxidase 919640 5173105 CMM_0813 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA oxidase YP_001221553.1 917535 D 443906 CDS YP_001221554.1 148271993 5173760 complement(919711..920055) 1 NC_009480.1 putative growth inhibitor (NP_713024.1| chpK [Leptospira interrogans serovar lai str. 56601]; CAA98393.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02452, PemK, PemK-like protein. PemK is a growth inhibitor in E. Coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis.; Function unclear; putative growth inhibitor 920055 5173760 CMM_0814 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative growth inhibitor YP_001221554.1 919711 R 443906 CDS YP_001221555.1 148271994 5173445 complement(920052..920303) 1 NC_009480.1 putative transcriptional regulator, CopG family(NP_336510.1| DNA-binding protein, CopG family [Mycobacterium tuberculosis CDC1551]; NP_713025.1| ChpI protein [Leptospira interrogans serovar lai str. 56601]). pfam01402, HTH_4, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected.; Conserved hypothetical protein; CopG family transcriptional regulator 920303 5173445 CMM_0815 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CopG family transcriptional regulator YP_001221555.1 920052 R 443906 CDS YP_001221556.1 148271995 5173202 complement(920376..921158) 1 NC_009480.1 putative esterase, lysophospholipase (ZP_00213268.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R18194]; ZP_00137144.2| COG2755: Lysophospholipase L1 and related esterases [Pseudomonas aeruginosa UCBPP-PA14]; NP_215591.1| hypothetical protein Rv1075c [Mycobacterium tuberculosis H37Rv]).; Family membership; putative esterase, lysophospholipase 921158 5173202 CMM_0816 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase, lysophospholipase YP_001221556.1 920376 R 443906 CDS YP_001221557.1 148271996 5173207 921336..922304 1 NC_009480.1 Proline iminopeptidase (Prolyl aminopeptidase) (YP_062972.1| prolyl aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058619.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Thermobifida fusca]). SPECIFICALLY CATALYZES THE REMOVAL OF N-TERMINAL PROLINE RESIDUES FROM PEPTIDES. pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; High confidence in function and specificity; proline iminopeptidase 922304 pipB 5173207 pipB Clavibacter michiganensis subsp. michiganensis NCPPB 382 proline iminopeptidase YP_001221557.1 921336 D 443906 CDS YP_001221558.1 148271997 5173651 complement(922323..922820) 1 NC_009480.1 putative glycerol-3-phosphate cytidylyltransferase (ZP_00227149.1| COG0615: Cytidylyltransferase [Kineococcus radiotolerans SRS30216]; NP_213944.1| glycerol-3-phosphate cytidyltransferase [Aquifex aeolicus]). pfam01467, CTP_transf_2, Cytidylyltransferase. This family includes: Cholinephosphate cytidylyltransferase, Glycerol-3-phosphate cytidylyltransferase. InterPro: Cytidylyltransferase.; Function unclear; glycerol-3-phosphate cytidylyltransferase 922820 tagD 5173651 tagD Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycerol-3-phosphate cytidylyltransferase YP_001221558.1 922323 R 443906 CDS YP_001221559.1 148271998 5174712 923198..925816 1 NC_009480.1 putative cell surface protein, potentially involved in polysaccharide synthesis (only weak similarities to sugar transferases, endoglucanases and RTX toxins; NP_631284.1| putative polysaccharide lyase [Streptomyces coelicolor A3(2)).; Function unclear; putative cell surface protein 925816 wcoA 5174712 wcoA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell surface protein YP_001221559.1 923198 D 443906 CDS YP_001221560.1 148271999 5173258 926113..928713 1 NC_009480.1 hypothetical protein potentially involved in polysaccharide metabolism (only weak similarities to glucanases, RTX toxins; NP_680916.1| ORF_ID:tlr0125 unknown protein [Thermosynechococcus elongatus BP-1]; NP_631284.1| putative polysaccharide lyase [Streptomyces coelicolor A3(2)]). InterPro: Proline-rich region; Function unclear; putative secreted protein 928713 wcoB 5173258 wcoB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001221560.1 926113 D 443906 CDS YP_001221561.1 148272000 5173280 929197..930732 1 NC_009480.1 putative undecaprenyl-phosphate sugar phosphotransferase (NP_959898.1| hypothetical protein MAP0964c [Mycobacterium avium subsp. paratuberculosis str. k10]; AAM94041.1| putative undecaprenyl-phosphate glycosyl-1-phosphate transferase; glucose-1-phosphate transferase [Streptomyces sp. 139]). Contains two domains,N-terminal: COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases; pfam02719, Polysacc_synt_2,Polysaccharide biosynthesis protein. C-terminal: COG2148,WcaJ, Sugar transferases involved in lipopolysaccharide synthesis; pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.; Specificity unclear; putative undecaprenyl-phosphate sugar phosphotransferase 930732 wcoC 5173280 wcoC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl-phosphate sugar phosphotransferase YP_001221561.1 929197 D 443906 CDS YP_001221562.1 148272001 5173300 930734..931966 1 NC_009480.1 putative glycosyltransferase (ZP_00081740.1| COG0438: Glycosyltransferase [Geobacter metallireducens]; CAC18356.1| putative rhamnosyltransferase [Streptococcus salivarius]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides.; Specificity unclear; putative glycosyltransferase 931966 wcoD 5173300 wcoD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221562.1 930734 D 443906 CDS YP_001221563.1 148272002 5173339 931963..932790 1 NC_009480.1 putative phosphatidylglycerophosphate synthase (ZP_00227148.1| COG2870: ADP-heptose synthase,bifunctional sugar kinase/ adenylyltransferase [Kineococcus radiotolerans SRS30216]; NP_823318.1| hypothetical protein [Streptomyces avermitilis MA-4680]; ZP_00057237.1| COG0558: Phosphatidylglycerophosphate synthase [Thermobifida fusca]). pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase.; Specificity unclear; putative phosphatidylglycerophosphate synthase 932790 wcoE 5173339 wcoE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatidylglycerophosphate synthase YP_001221563.1 931963 D 443906 CDS YP_001221564.1 148272003 5173361 932787..934028 1 NC_009480.1 putative glycosyl transferase (NP_103517.1| unknown protein [Mesorhizobium loti MAFF303099]; AAN64562.1| glycosyltransferase [Streptococcus gordonii]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides.; Function unclear; putative glycosyltransferase 934028 wcoF 5173361 wcoF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221564.1 932787 D 443906 CDS YP_001221565.1 148272004 5173372 934078..939963 1 NC_009480.1 hypothetical protein (only weak similarities to collagenases, glucanases and RTX toxins; ZP_00227150.1| hypothetical protein Krad06001747 [Kineococcus radiotolerans SRS30216]; ZP_00116912.1| COG3468: Type V secretory pathway, adhesin AidA [Cytophaga hutchinsonii]; NP_518236.1| PUTATIVE HEMAGGLUTININ-RELATED PROTEIN [Ralstonia solanacearum]). pfam00801, PKD, PKD domain.; Function unclear; putative cell surface protein 939963 wcoG 5173372 wcoG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell surface protein YP_001221565.1 934078 D 443906 CDS YP_001221566.1 148272005 5173412 940128..941498 1 NC_009480.1 Hypothetical protein; hypothetical protein 941498 wcoH 5173412 wcoH Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221566.1 940128 D 443906 CDS YP_001221567.1 148272006 5173395 941495..942883 1 NC_009480.1 putative capsular polysaccharide synthesis enzyme (CAF19058.1| cell surface polysaccharide biosynthesis / Chain length determinant protein [Corynebacterium glutamicum ATCC 13032]; NP_696399.1| possible Etk- like tyrosine kinase involved in Eps biosynthesis [Bifidobacterium longum NCC2705]). , Contains two domains. N-terminal: COG3944, Capsular polysaccharide biosynthesis protein; pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. , C-terminal: COG0489, Mrp, ATPases involved in chromosome partitioning; Specificity unclear; capsular polysaccharide synthesis enzyme 942883 wcoI 5173395 wcoI Clavibacter michiganensis subsp. michiganensis NCPPB 382 capsular polysaccharide synthesis enzyme YP_001221567.1 941495 D 443906 CDS YP_001221568.1 148272007 5175775 943579..944319 1 NC_009480.1 hypothetical protein (CAI37418.1| putative DNA restriction-modification system, hypothetical protein [Corynebacterium jeikeium K411]; NP_862180.1| hypothetical protein [Streptomyces violaceoruber]).; hypothetical protein 944319 5175775 CMM_0828 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221568.1 943579 D 443906 CDS YP_001221569.1 148272008 5173077 complement(946682..947329) 1 NC_009480.1 hypothetical protein, putative membrane protein; hypothetical protein 947329 wcoK 5173077 wcoK Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221569.1 946682 R 443906 CDS YP_001221570.1 148272009 5173396 complement(947529..949463) 1 NC_009480.1 Region start changed from 949550 to 949463 (-87 bases); putative glycosyltransferase 949463 5173396 CMM_0830 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221570.1 947529 R 443906 CDS YP_001221571.1 148272010 5173325 949624..950673 1 NC_009480.1 putative glycosyl transferase (NP_637800.1| GumI protein [Xanthomonas campestris pv. campestris str. ATCC 33913] ; ZP_00228119.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyl transferase 950673 wcoM 5173325 wcoM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221571.1 949624 D 443906 CDS YP_001221572.1 148272011 5173481 950845..952464 1 NC_009480.1 putative membrane protein involved in the export of polysaccharides, MOP family (NP_637799.1| GumJ protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00039159.1| COG2244: Membrane protein involved in the export of O-antigen and teichoic acid [Xylella fastidiosa Dixon]; CAF19065.1| putative translocase involved in export of a cell surface polysaccaride [Corynebacterium glutamicum ATCC 13032]). , , pfam01943, Polysacc_synt,Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. InterPro: Polysaccharide biosynthesis protein.; Specificity unclear; putative membrane protein involved in the export of polysaccharides 952464 wzx3 5173481 wzx3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane protein involved in the export of polysaccharides YP_001221572.1 950845 D 443906 CDS YP_001221573.1 148272012 5173971 952628..953671 1 NC_009480.1 putative nucleotide sugar epimerase (ZP_00226592.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; ZP_00064898.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Microbulbifer degradans 2-40]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative nucleotide sugar epimerase 953671 wcoN 5173971 wcoN Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleotide sugar epimerase YP_001221573.1 952628 D 443906 CDS YP_001221574.1 148272013 5173447 complement(953701..954522) 1 NC_009480.1 conserved membrane protein (ZP_00227474.1| hypothetical protein Krad06004208 [Kineococcus radiotolerans SRS30216]; NP_736959.1| hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein 954522 wcoO 5173447 wcoO Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221574.1 953701 R 443906 CDS YP_001221575.1 148272014 5173500 954603..955109 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_782612.1| transcriptional regulator, marR family [Clostridium tetani E88]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein; Specificity unclear; MarR family transcriptional regulator 955109 wcoP 5173500 wcoP Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221575.1 954603 D 443906 CDS YP_001221576.1 148272015 5173474 955106..955870 1 NC_009480.1 conserved hypothetical protein (ZP_00198897.1| COG3361: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_625469.1| conserved hypothetical protein SCG11A.10c [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 955870 wcoQ 5173474 wcoQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221576.1 955106 D 443906 CDS YP_001221577.1 148272016 5173525 complement(955907..957742) 1 NC_009480.1 putative glycosyl hydrolase, family 15 (NP_636453.1| conserved hypothetical protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_733605.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15.; Specificity unclear; glycoside hydrolase family protein 957742 wcoR 5173525 wcoR Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycoside hydrolase family protein YP_001221577.1 955907 R 443906 CDS YP_001221578.1 148272017 5173534 957982..958515 1 NC_009480.1 conserved hypothetical protein (NP_630535.1| conserved hypothetical protein SC9B5.17 [Streptomyces coelicolor A3(2)]; Q9EYI6|Y189_STRNO Hypothetical 19.0 kDa protein in sno 5'region (ORF7); NP_663093.1| histone macro-H2A1-related protein [Chlorobium tepidum TLS]).; Function unclear; hypothetical protein 958515 5173534 CMM_0838 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221578.1 957982 D 443906 CDS YP_001221579.1 148272018 5174949 959321..960616 1 NC_009480.1 putative membrane bound metalloprotease (YP_062953.1| cell wall binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00109858.1| COG0739: Membrane proteins related to metalloendopeptidases, family M23 [Nostoc punctiforme]). pfam01551, Peptidase_M37,Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities.; Function unclear; putative membrane bound metalloprotease 960616 5174949 CMM_0839 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane bound metalloprotease YP_001221579.1 959321 D 443906 CDS YP_001221580.1 148272019 5173542 960630..962003 1 NC_009480.1 putative membrane associated protein (NP_787277.1| NPL/P60 family secreted protein [Tropheryma whipplei str. Twist]; NP_471978.1| peptidoglycan lytic protein P45 [Listeria innocua]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins. InterPro: NLP/P60.; Function unclear; NPL/P60 family secreted protein 962003 5173542 CMM_0840 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NPL/P60 family secreted protein YP_001221580.1 960630 D 443906 CDS YP_001221581.1 148272020 5173289 complement(962140..962667) 1 NC_009480.1 putative inorganic pyrophosphatase (YP_062951.1| inorganic pyrophosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; O06379|IPYR_MYCTU Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)). pfam00719,Pyrophosphatase, Inorganic pyrophosphatase.; High confidence in function and specificity; hypothetical protein 962667 ipyA 5173289 ipyA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221581.1 962140 R 443906 CDS YP_001221582.1 148272021 5175049 962722..963747 1 NC_009480.1 putative ATPase of the PP-loop superfamily implicated in cell cycle control (YP_062950.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058801.1| COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control [Thermobifida fusca]). pfam01171, ATP_bind_3, PP-loop family. This family of proteins belongs to the PP-loop superfamily.; Specificity unclear; putative cell cycle protein 963747 5175049 CMM_0842 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell cycle protein YP_001221582.1 962722 D 443906 CDS YP_001221583.1 148272022 5175425 963749..964300 1 NC_009480.1 Hypoxanthine-guanine phosphoribosyltransferase (YP_062949.1| hypoxanthine phosphoribosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825842.1| putative hypoxanthine phosphoribosyltransferase [Streptomyces avermitilis MA-4680]). pfam00156,Pribosyltran, Phosphoribosyl transferase domain. InterPro: Phosphoribosyl transferase; High confidence in function and specificity; hypothetical protein 964300 hptA 5175425 hptA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221583.1 963749 D 443906 CDS YP_001221584.1 148272023 5175489 964458..966458 1 NC_009480.1 cell division protein, membrane-bound ATP-dependent protease (YP_062948.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226547.1| COG0465: ATP-dependent Zn proteases [Kineococcus radiotolerans SRS30216]. pfam06480, FtsH_ext, FtsH Extracellular. This domain is found in the FtsH family of proteins. FtsH is the only membrane-bound ATP-dependent protease universally conserved in prokaryotes. pfam00004, AAA, ATPase family associated with various cellular activities (AAA). pfam01434, Peptidase_M41, Peptidase family M41.; High confidence in function and specificity; cell division protein, membrane-bound ATP-dependent protease 966458 ftsH 5175489 ftsH Clavibacter michiganensis subsp. michiganensis NCPPB 382 cell division protein, membrane-bound ATP-dependent protease YP_001221584.1 964458 D 443906 CDS YP_001221585.1 148272024 5173969 966463..967047 1 NC_009480.1 GTP cyclohydrolase I (YP_062947.1| GTP cyclohydrolase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_870186.1| GTP cyclohydrolase I [Pirellula sp. 1]). catalytic activity: gtp + 2 h(2)o = formate + 2-amino-4-hydroxy-6- (erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate. pathway: tetrahydrofolate biosynthesis; first step. pfam01227,GTP_cyclohydroI, GTP cyclohydrolase I. folE: GTP cyclohydrolase I; High confidence in function and specificity; hypothetical protein 967047 folE 5173969 folE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221585.1 966463 D 443906 CDS YP_001221586.1 148272025 5173640 967044..967916 1 NC_009480.1 dihydropteroate synthase (Dihydropteroate pyrophosphorylase)(YP_062946.1| dihydropteroate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293163.1| COG0294: Dihydropteroate synthase and related enzymes [Thermobifida fusca]). pfam00809, Pterin_bind, Pterin binding enzyme.; High confidence in function and specificity; dihydropteroate synthase 967916 folP 5173640 folP Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydropteroate synthase YP_001221586.1 967044 D 443906 CDS YP_001221587.1 148272026 5173654 967921..968631 1 NC_009480.1 Hypothetical protein; hypothetical protein 968631 5173654 CMM_0847 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221587.1 967921 D 443906 CDS YP_001221588.1 148272027 5173082 968625..969515 1 NC_009480.1 bifunctional folate synthesis protein [Includes: Dihydroneopterin aldolase (EC 4.1.2.25) (DHNA) and 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (78- dihydro-6-hydroxymethylpterin pyrophosphokinase)] (NP_696836.1| probable bifunctional folate synthesis protein [includes: dihydroneopterin aldolase (DhnA); 2-amino-4-hydroxy-6-hydroxy- methyldihydropteridine pyrophosphokinase [Bifidobacterium longum NCC2705]; NP_561938.1| bifunctional folate synthesis protein [Clostridium perfringens str. 13]). COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism]; pfam02152, FolB,Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. pfam01288, HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).; High confidence in function and specificity; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase/dihydroneopterin aldolase 969515 folBK 5173082 folBK Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase/dihydroneopterin aldolase YP_001221588.1 968625 D 443906 CDS YP_001221589.1 148272028 5173603 969512..969994 1 NC_009480.1 conserved membrane protein (CAB08939.1| PROBABLE CONSERVED SECRETED PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_940327.1| Putative membrane protein [Corynebacterium diphtheriae]).; Conserved hypothetical protein; hypothetical protein 969994 5173603 CMM_0849 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221589.1 969512 D 443906 CDS YP_001221590.1 148272029 5173075 970044..970532 1 NC_009480.1 conserved membrane protein (YP_062943.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226554.1| COG3402: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_825854.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam03703, DUF304,Bacterial membrane flanked domain. Domain found in uncharacterised family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices.; hypothetical protein 970532 5173075 CMM_0850 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221590.1 970044 D 443906 CDS YP_001221591.1 148272030 5174488 970529..972331 1 NC_009480.1 conserved membrane protein (NP_737260.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226555.1| COG3428: Predicted membrane protein [Kineococcus radiotolerans SRS30216]). three times pfam03703, DUF304, Bacterial membrane flanked domain. Domain found in uncharacterised family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices.; Function unclear; hypothetical protein 972331 5174488 CMM_0851 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221591.1 970529 D 443906 CDS YP_001221592.1 148272031 5173022 972328..973089 1 NC_009480.1 conserved hypothetical protein (COG5495, COG5495,Uncharacterized conserved protein; ZP_00058789.1| hypothetical protein [Thermobifida fusca]; NP_825863.1| hypothetical protein SAV4686 [Streptomyces avermitilis MA-4680]).; hypothetical protein 973089 5173022 CMM_0852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221592.1 972328 D 443906 CDS YP_001221593.1 148272032 5173054 973132..974010 1 NC_009480.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 974010 panC 5173054 panC Clavibacter michiganensis subsp. michiganensis NCPPB 382 pantoate--beta-alanine ligase YP_001221593.1 973132 D 443906 CDS YP_001221594.1 148272033 5175390 974122..975663 1 NC_009480.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 975663 lysS 5175390 lysS Clavibacter michiganensis subsp. michiganensis NCPPB 382 lysyl-tRNA synthetase YP_001221594.1 974122 D 443906 CDS YP_001221595.1 148272034 5173629 975670..975795 1 NC_009480.1 hypothetical protein 975795 5173629 CMM_0855 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221595.1 975670 D 443906 CDS YP_001221596.1 148272035 5174032 975817..975999 1 NC_009480.1 hypothetical protein (YP_062937.1| hypothetical protein Lxx21380 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227406.1| hypothetical protein Krad06000875 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 975999 5174032 CMM_0856 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221596.1 975817 D 443906 CDS YP_001221597.1 148272036 5173399 976162..978672 1 NC_009480.1 ATP-dependent protease, ATPase subunit (NP_627581.1| putative Clp-family ATP-binding protease [Streptomyces coelicolor A3(2)]; NP_959395.1| ClpC [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam02861, Clp_N, Clp amino terminal domain (twice). pfam00004, AAA, ATPase family associated with various cellular activities (AAA) (twice). clpX: ATP-dependent Clp protease ATP; High confidence in function and specificity; ATP-dependent protease, ATPase subunit 978672 clpC 5173399 clpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent protease, ATPase subunit YP_001221597.1 976162 D 443906 CDS YP_001221598.1 148272037 5173616 978839..979726 1 NC_009480.1 putative UDP-glucose 4-epimerase (ZP_00225979.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_103218.1| UDP-galactose 4-epimerase [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative UDP-glucose 4-epimerase 979726 galE2 5173616 galE2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-glucose 4-epimerase YP_001221598.1 978839 D 443906 CDS YP_001221599.1 148272038 5174705 979723..980700 1 NC_009480.1 putative oxidoreductase, aldo/keto reductase family (ZP_00279967.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Burkholderia fungorum LB400]; NP_822773.1| putative aldo/keto reductase [Streptomyces avermitilis MA-4680]). pfam00248,Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 980700 5174705 CMM_0859 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001221599.1 979723 D 443906 CDS YP_001221600.1 148272039 5172929 981002..981517 1 NC_009480.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 981517 rplJ 5172929 rplJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L10 YP_001221600.1 981002 D 443906 CDS YP_001221601.1 148272040 5173754 981593..981976 1 NC_009480.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 981976 rplL 5173754 rplL Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L7/L12 YP_001221601.1 981593 D 443906 CDS YP_001221602.1 148272041 5173834 complement(982055..983674) 1 NC_009480.1 putative transcriptional regulator, C-terminal response regulator domain (ZP_00140987.1| COG2202: FOG: PAS/PAC domain [Pseudomonas aeruginosa UCBPP-PA14]). pfam00196, GerE, Bacterial regulatory proteins, luxR family. InterPro: Bacterial regulatory protein LuxR family.; Function unclear; putative transcriptional regulator 983674 5173834 CMM_0862 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001221602.1 982055 R 443906 CDS YP_001221603.1 148272042 5172959 983800..984279 1 NC_009480.1 putative transcriptional regulator, MarR family (CAB02063.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_628214.1| putative marR regulatory protein [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 984279 5172959 CMM_0863 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221603.1 983800 D 443906 CDS YP_001221604.1 148272043 5172969 984361..985593 1 NC_009480.1 putative multidrug efflux MFS permease (O06473|YFMO_BACSU Multidrug efflux protein yfmO; ZP_00226584.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative multidrug efflux MFS permease 985593 5172969 CMM_0864 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug efflux MFS permease YP_001221604.1 984361 D 443906 CDS YP_001221605.1 148272044 5172943 complement(985636..986655) 1 NC_009480.1 transcriptional regulator, LacI family (ZP_00048869.2| COG1609: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_695717.1| probable LacI-type transcriptional regulator [Bifidobacterium longum NCC2705]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. The periplasmic binding proteins are the primary receptors for chemotaxis and transport of many sugar based solutes.; Specificity unclear; LacI family transcription regulator 986655 5172943 CMM_0865 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcription regulator YP_001221605.1 985636 R 443906 CDS YP_001221606.1 148272045 5172991 986970..988334 1 NC_009480.1 putative alpha-glucoside ABC transporter, substrate-binding protein (ZP_00292314.1| COG1653: ABC-type sugar transport system, periplasmic component [Thermobifida fusca]; ZP_00201205.1| COG1653: ABC-type sugar transport system, periplasmic component [Crocosphaera watsonii WH 8501]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative alpha-glucoside ABC transporter,substrate-binding protein 988334 5172991 CMM_0866 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-glucoside ABC transporter,substrate-binding protein YP_001221606.1 986970 D 443906 CDS YP_001221607.1 148272046 5172980 988471..989442 1 NC_009480.1 putative alpha-glucoside ABC transporter, permease component (ZP_00292313.1| COG1175: ABC-type sugar transport systems, permease components [Thermobifida fusca]; ZP_00201204.1| COG1175: ABC-type sugar transport systems, permease components [Crocosphaera watsonii WH 8501]).; Specificity unclear; putative alpha-glucoside ABC transporter,permease component 989442 5172980 CMM_0867 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-glucoside ABC transporter,permease component YP_001221607.1 988471 D 443906 CDS YP_001221608.1 148272047 5173046 989439..990428 1 NC_009480.1 putative alpha-glucoside ABC transport system,permease component (ZP_00058629.1| COG0395: ABC-type sugar transport system, permease component [Thermobifida fusca]; NP_442748.1| membrane bound sugar transport protein [Synechocystis sp. PCC 6803]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative alpha-glucoside ABC transport system,permease component 990428 5173046 CMM_0868 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-glucoside ABC transport system,permease component YP_001221608.1 989439 D 443906 CDS YP_001221609.1 148272048 5173014 990551..992431 1 NC_009480.1 ABC transporter consisting of fused permease and ATPase domains (AAF67494.1| NovA [Streptomyces caeruleus]; ZP_00226145.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Kineococcus radiotolerans SRS30216]). pfam00664,ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; ABC transporter permease/ATPase 992431 5173014 CMM_0869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ABC transporter permease/ATPase YP_001221609.1 990551 D 443906 CDS YP_001221610.1 148272049 5173041 complement(992488..993255) 1 NC_009480.1 conserved hypothetical protein (AAS20097.1| hypothetical protein [Arthrobacter aurescens]; NP_827127.1| putative secreted protein [Streptomyces avermitilis MA-4680]). pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function (twice). TIGR00729: ribonuclease HII; hypothetical protein 993255 5173041 CMM_0870 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221610.1 992488 R 443906 CDS YP_001221611.1 148272050 5173025 complement(993258..994001) 1 NC_009480.1 conserved hypothetical protein (AAS20096.1| hypothetical protein [Arthrobacter aurescens]; ZP_00293399.1| hypothetical protein Tfus02000754 [Thermobifida fusca]).; hypothetical protein 994001 5173025 CMM_0871 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221611.1 993258 R 443906 CDS YP_001221612.1 148272051 5173068 994171..995535 1 NC_009480.1 putative cystathionine beta-synthase (Serine sulfhydrase) (BAB96806.1| probable cystathionine beta-synthase [Rhodococcus erythropolis]; ZP_00227382.1| COG0031: Cysteine synthase [Kineococcus radiotolerans SRS30216]). pfam00291, PALP, Pyridoxal-phosphate dependent enzyme. COG0517, FOG: CBS domain [General function prediction only], pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; High confidence in function and specificity; putative cystathionine beta-synthase 995535 cysB 5173068 cysB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cystathionine beta-synthase YP_001221612.1 994171 D 443906 CDS YP_001221613.1 148272052 5174798 995583..996755 1 NC_009480.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 996755 metB 5174798 metB Clavibacter michiganensis subsp. michiganensis NCPPB 382 cystathionine gamma-synthase YP_001221613.1 995583 D 443906 CDS YP_001221614.1 148272053 5174739 complement(996801..997559) 1 NC_009480.1 putative Ribonuclease H (YP_062422.1| ribonuclease H [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056416.1| ribonuclease H [Propionibacterium acnes KPA171202]). pfam00075, RnaseH, RNase H. RNase H digests the RNA strand of an RNA/DNA hybrid. pfam01402, HTH_4, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerisation and not DNA binding as might have been expected.; High confidence in function and specificity; ribonuclease H 997559 rnhA 5174739 rnhA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonuclease H YP_001221614.1 996801 R 443906 CDS YP_001221615.1 148272054 5173061 997737..998759 1 NC_009480.1 putative transcriptional regulator, LacI-family (NP_630441.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00198171.1| hypothetical protein Krad024574 [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 998759 5173061 CMM_0875 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001221615.1 997737 D 443906 CDS YP_001221616.1 148272055 5173055 998939..1000642 1 NC_009480.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 1000642 araB 5173055 araB Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribulokinase YP_001221616.1 998939 D 443906 CDS YP_001221617.1 148272056 5175021 1000639..1001349 1 NC_009480.1 catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; L-ribulose-5-phosphate 4-epimerase 1001349 araD 5175021 araD Clavibacter michiganensis subsp. michiganensis NCPPB 382 L-ribulose-5-phosphate 4-epimerase YP_001221617.1 1000639 D 443906 CDS YP_001221618.1 148272057 5173360 1001346..1002863 1 NC_009480.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 1002863 araA 5173360 araA Clavibacter michiganensis subsp. michiganensis NCPPB 382 L-arabinose isomerase YP_001221618.1 1001346 D 443906 CDS YP_001221619.1 148272058 5174052 1002940..1004070 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (ZP_00198172.2| COG4213: ABC-type xylose transport system, periplasmic component [Kineococcus radiotolerans SRS30216]; NP_769848.1| ABC transporter sugar-binding protein [Bradyrhizobium japonicum USDA 110]). pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 1004070 5174052 CMM_0879 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001221619.1 1002940 D 443906 CDS YP_001221620.1 148272059 5173119 1004248..1005777 1 NC_009480.1 putative sugar ABC transporter, ATPase component (ZP_00225839.1| COG1129: ABC-type sugar transport system,ATPase component [Kineococcus radiotolerans SRS30216]; NP_826945.1| putative sugar ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]). pfam00005,ABC_tran, ABC transporter (twice, two fused ATPases).; Specificity unclear; putative sugar ABC transporter, ATPase component 1005777 5173119 CMM_0880 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATPase component YP_001221620.1 1004248 D 443906 CDS YP_001221621.1 148272060 5173100 1005783..1006970 1 NC_009480.1 putative sugar ABC transporter, permease component (AAD45714.1| L-arabinose membrane permease [Geobacillus stearothermophilus]; NP_626652.1| putative sugar transport permease [Streptomyces coelicolor A3(2)]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component (twice, two fused permeases).; Specificity unclear; putative sugar ABC transporter, permease component 1006970 5173100 CMM_0881 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221621.1 1005783 D 443906 CDS YP_001221622.1 148272061 5173138 complement(1007319..1008512) 1 NC_009480.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1008512 xylA 5173138 xylA Clavibacter michiganensis subsp. michiganensis NCPPB 382 xylose isomerase YP_001221622.1 1007319 R 443906 CDS YP_001221623.1 148272062 5174248 1008717..1010219 1 NC_009480.1 putative beta-glucosidase (ZP_00188825.3| COG2723: Beta-glucosidase/ 6-phospho-beta-glucosidase/beta-galactosidase [Kineococcus radiotolerans SRS30216]; S45675 beta-glucosidase (EC 3.2.1.21) - Streptomyces sp. (strain QM-B814)). pfam00232, Glyco_hydro_1, Glycosyl hydrolase family 1.; Specificity unclear; beta-glucosidase 1010219 bglJ 5174248 bglJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-glucosidase YP_001221623.1 1008717 D 443906 CDS YP_001221624.1 148272063 5175482 1010216..1010782 1 NC_009480.1 putative acetyltransferase (ZP_00227685.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Kineococcus radiotolerans SRS30216]; NP_389071.1|; Function unclear; putative acetyltransferase 1010782 5175482 CMM_0884 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221624.1 1010216 D 443906 CDS YP_001221625.1 148272064 5173155 complement(1010813..1011250) 1 NC_009480.1 putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_790665.1| transcriptional regulator, MarR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 1011250 5173155 CMM_0885 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221625.1 1010813 R 443906 CDS YP_001221626.1 148272065 5173174 complement(1011375..1011710) 1 NC_009480.1 hypothetical protein 1011710 5173174 CMM_0886 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221626.1 1011375 R 443906 CDS YP_001221627.1 148272066 5174771 complement(1011839..1012795) 1 NC_009480.1 putative transcriptional regulator, LysR family (NP_628924.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00292125.1| COG0583: Transcriptional regulator [Thermobifida fusca]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; hypothetical protein 1012795 5174771 CMM_0887 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221627.1 1011839 R 443906 CDS YP_001221628.1 148272067 5173201 1012877..1013932 1 NC_009480.1 putative selenocysteine lyase (ZP_00057151.1| COG0520: Selenocysteine lyase [Thermobifida fusca]; NP_626135.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00266, Aminotran_5,Aminotransferase class-V.; Family membership; hypothetical protein 1013932 5173201 CMM_0888 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221628.1 1012877 D 443906 CDS YP_001221629.1 148272068 5173190 1014064..1015299 1 NC_009480.1 putative MFS-type efflux transporter (ZP_00198278.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_827094.1| putative bicyclomycin resistance protein [Streptomyces avermitilis MA-4680]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS-type efflux transporter 1015299 5173190 CMM_0889 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS-type efflux transporter YP_001221629.1 1014064 D 443906 CDS YP_001221630.1 148272069 5173263 1015340..1016434 1 NC_009480.1 putative membrane protein (NP_822458.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00056876.1| hypothetical protein [Thermobifida fusca]).; Function unclear; hypothetical protein 1016434 5173263 CMM_0890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221630.1 1015340 D 443906 CDS YP_001221631.1 148272070 5173219 complement(1016431..1017318) 1 NC_009480.1 putative streptomycin-kinase(AAN18030.1| putative streptomycin-3-kinase [Pseudomonas aurantiaca]; NP_250549.1| streptomycin 3''-phosphotransferase [Pseudomonas aeruginosa PA01]). pfam04655, APH_6_hur,Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.; Specificity unclear; putative streptomycin phosphotransferase 1017318 strB 5173219 strB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative streptomycin phosphotransferase YP_001221631.1 1016431 R 443906 CDS YP_001221632.1 148272071 5175640 complement(1017315..1017965) 1 NC_009480.1 hypothetical protein 1017965 5175640 CMM_0892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221632.1 1017315 R 443906 CDS YP_001221633.1 148272072 5173166 complement(1018383..1021241) 1 NC_009480.1 putative transcriptional regulator, LuxR family (ZP_00228816.1| COG2771: DNA-binding HTH domain-containing proteins [Kineococcus radiotolerans SRS30216]; NP_733725.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_335345.1| transcriptional regulator, LuxR family [Mycobacterium tuberculosis CDC1551]). pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; LuxR family transcriptional regulator 1021241 5173166 CMM_0893 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LuxR family transcriptional regulator YP_001221633.1 1018383 R 443906 CDS YP_001221634.1 148272073 5173233 complement(1021575..1022228) 1 NC_009480.1 putative nucleoside-diphosphate-sugar epimerase (ZP_00058107.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]; NP_826075.1| hypothetical protein SAV4898 [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate-sugar epimerase 1022228 5173233 CMM_0894 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001221634.1 1021575 R 443906 CDS YP_001221635.1 148272074 5175704 1022461..1024578 1 NC_009480.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 1024578 ptaA 5175704 ptaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphate acetyltransferase YP_001221635.1 1022461 D 443906 CDS YP_001221636.1 148272075 5174998 1024644..1025834 1 NC_009480.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1025834 ackA 5174998 ackA Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetate kinase YP_001221636.1 1024644 D 443906 CDS YP_001221637.1 148272076 5175462 1026122..1031185 1 NC_009480.1 putative cell surface protein (putative adhesin,putative hemagglutinin/hemolysin-related protein) (NP_879893.1| putative outer membrane ligand binding protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein 1031185 5175462 CMM_0897 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221637.1 1026122 D 443906 CDS YP_001221638.1 148272077 5173278 1031353..1032204 1 NC_009480.1 hypothetical protein 1032204 5173278 CMM_0898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221638.1 1031353 D 443906 CDS YP_001221639.1 148272078 5173316 1032201..1033412 1 NC_009480.1 conserved membrane protein (NP_825339.1| hypothetical protein SAV4162 [Streptomyces avermitilis MA-4680]; NP_864673.1| conserved hypothetical protein [Pirellula sp. 1]).; hypothetical protein 1033412 5173316 CMM_0899 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221639.1 1032201 D 443906 CDS YP_001221640.1 148272079 5173308 1033458..1035938 1 NC_009480.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1035938 5173308 CMM_0900 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III subunits gamma and tau YP_001221640.1 1033458 D 443906 CDS YP_001221641.1 148272080 5173333 1035945..1036544 1 NC_009480.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1036544 recR 5173333 recR Clavibacter michiganensis subsp. michiganensis NCPPB 382 recombination protein RecR YP_001221641.1 1035945 D 443906 CDS YP_001221642.1 148272081 5173179 1036654..1037919 1 NC_009480.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1037919 lysC 5173179 lysC Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate kinase YP_001221642.1 1036654 D 443906 CDS YP_001221643.1 148272082 5175880 1037969..1039066 1 NC_009480.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1039066 asdA 5175880 asdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate-semialdehyde dehydrogenase YP_001221643.1 1037969 D 443906 CDS YP_001221644.1 148272083 5174621 1039154..1040632 1 NC_009480.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 1040632 mqoA 5174621 mqoA Clavibacter michiganensis subsp. michiganensis NCPPB 382 malate:quinone oxidoreductase YP_001221644.1 1039154 D 443906 CDS YP_001221645.1 148272084 5174140 1040702..1041886 1 NC_009480.1 conserved hypothetical protein (YP_061469.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; CAB01265.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_630564.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam04055, Radical_SAM, Radical SAM superfamily.; High confidence in function and specificity; hypothetical protein 1041886 5174140 CMM_0905 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221645.1 1040702 D 443906 CDS YP_001221646.1 148272085 5173351 1041957..1042655 1 NC_009480.1 putative two-component system, response regulator (NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]; ZP_00033625.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Burkholderia fungorum]). pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1042655 5173351 CMM_0906 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001221646.1 1041957 D 443906 CDS YP_001221647.1 148272086 5173379 1042656..1043330 1 NC_009480.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1043330 tdkA 5173379 tdkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 thymidine kinase YP_001221647.1 1042656 D 443906 CDS YP_001221648.1 148272087 5175978 1043686..1045080 1 NC_009480.1 putative tyrosine-protein kinase (NP_599595.1| putative ATPase involved in chromosome partitioning [Corynebacterium glutamicum ATCC 13032]; ZP_00190418.2| COG0489: ATPases involved in chromosome partitioning [Kineococcus radiotolerans SRS30216]). , N-terminal: COG3944, Capsular polysaccharide biosynthesis protein,pfam02706, Wzz, Chain length determinant protein. This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This region is also found as part of bacterial tyrosine kinases. , C-terminal: COG0489, Mrp,ATPases involved in chromosome partitioning; Function unclear; putative tyrosine-protein kinase 1045080 5175978 CMM_0908 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tyrosine-protein kinase YP_001221648.1 1043686 D 443906 CDS YP_001221649.1 148272088 5173404 1045419..1046369 1 NC_009480.1 hypothetical protein (BAB97739.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 1046369 5173404 CMM_0909 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221649.1 1045419 D 443906 CDS YP_001221650.1 148272089 5173386 1046366..1048186 1 NC_009480.1 hypothetical protein (ZP_00120927.1| COG1463: ABC-type transport system involved in resistance to organic solvents, periplasmic component [Bifidobacterium longum DJO10A]; ZP_00120551.1| COG0840: Methyl-accepting chemotaxis protein [Bifidobacterium longum DJO10A]; ZP_00199275.1| hypothetical protein Krad06001109 [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 1048186 5173386 CMM_0910 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221650.1 1046366 D 443906 CDS YP_001221651.1 148272090 5173439 1048274..1048858 1 NC_009480.1 hypothetical protein 1048858 5173439 CMM_0911 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221651.1 1048274 D 443906 CDS YP_001221652.1 148272091 5173420 1049131..1049721 1 NC_009480.1 hypothetical protein 1049721 5173420 CMM_0912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221652.1 1049131 D 443906 CDS YP_001221653.1 148272092 5173462 complement(1049761..1050288) 1 NC_009480.1 conserved membrane protein, putative resistance protein (NP_347289.1| Uncharacterized conserved membrane protein, ; NP_832420.1| Teicoplanin resistance protein vanZ [Bacillus cereus ATCC 14579]). pfam04892, VanZ, VanZ like family.; Function unclear; hypothetical protein 1050288 5173462 CMM_0913 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221653.1 1049761 R 443906 CDS YP_001221654.1 148272093 5173432 1050375..1051388 1 NC_009480.1 putative flavin-dependent oxidoreductase/monooxygenase (NP_826413.1| putative LuxAB-like protein (oxygenase) [Streptomyces avermitilis MA-4680]; CAF25096.1| putative alkanalmonooxygenase [Yersinia enterocolitica]) pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: Bacterial luciferase.; Function unclear; putative flavin-dependent oxidoreductase/monooxygenase 1051388 5173432 CMM_0914 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative flavin-dependent oxidoreductase/monooxygenase YP_001221654.1 1050375 D 443906 CDS YP_001221655.1 148272094 5173493 1051481..1053715 1 NC_009480.1 putative penicillin-binding protein (YP_061622.1| penicillin-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789643.1| putative penicillin-binding protein/transpeptidase [Tropheryma whipplei TW08/27]; ZP_00120566.1| hypothetical protein Blon020421 [Bifidobacterium longum DJO10A]). Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. pfam00912, Transgly, Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. pfam00905, Transpeptidase, Penicillin binding protein transpeptidase domain. The active site serine is conserved in all members of this family.; Specificity unclear; putative penicillin-binding protein 1053715 pbpC 5173493 pbpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative penicillin-binding protein YP_001221655.1 1051481 D 443906 CDS YP_001221656.1 148272095 5175496 1053861..1055141 1 NC_009480.1 putative acyltransferase (ZP_00226320.1| COG1835: Predicted acyltransferases [Kineococcus radiotolerans SRS30216]; NP_298068.1| O-antigen acetylase [Xylella fastidiosa 9a5c]; ZP_00058493.1| COG1835: Predicted acyltransferases [Thermobifida fusca]). pfam01757,Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative acyltransferase 1055141 5175496 CMM_0916 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyltransferase YP_001221656.1 1053861 D 443906 CDS YP_001221657.1 148272096 5173450 1055138..1055590 1 NC_009480.1 hypothetical membrane protein; Hypothetical protein; hypothetical protein 1055590 5173450 CMM_0917 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221657.1 1055138 D 443906 CDS YP_001221658.1 148272097 5173927 complement(1055835..1056779) 1 NC_009480.1 putative phosphohydrolase (YP_061478.1| phosphohydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789644.1| putative secreted protein [Tropheryma whipplei TW08/27]). InterPro: Serine/threonine specific protein phosphatase. pfam00149, Metallophos,Calcineurin-like phosphoesterase. This family includes a diverse range of phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as nucleases such as bacterial SbcD or yeast MRE11.; Function unclear; putative phosphohydrolase 1056779 5173927 CMM_0918 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphohydrolase YP_001221658.1 1055835 R 443906 CDS YP_001221659.1 148272098 5173508 complement(1056779..1059316) 1 NC_009480.1 putative membrane carboxypeptidase (penicillin-binding protein) (YP_061622.1| penicillin-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789643.1| putative penicillin-binding protein/transpeptidase [Tropheryma whipplei TW08/27]). InterPro: Penicillin binding protein transpeptidase domain. pfam00912,Transgly, Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyses the polymerisation of murein glycan chains. pfam00905, Transpeptidase, Penicillin binding protein transpeptidase domain. The active site serine is conserved in all members of this family. pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate.; Specificity unclear; putative penicillin-binding protein 1059316 pbpD 5173508 pbpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative penicillin-binding protein YP_001221659.1 1056779 R 443906 CDS YP_001221660.1 148272099 5175512 1059422..1059604 1 NC_009480.1 conserved hypothetical protein (NP_787831.1| unknown [Tropheryma whipplei str. Twist]; NP_938688.1| Conserved hypothetical protein [Corynebacterium diphtheriae]).; hypothetical protein 1059604 5175512 CMM_0920 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221660.1 1059422 D 443906 CDS YP_001221661.1 148272100 5173557 1059604..1060068 1 NC_009480.1 putative endoribonuclease, putative translation initiation inhibitor (NP_627772.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959330.1| hypothetical protein MAP0396 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01042, Ribonuc_L-PSP,Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. TIGR00004: endoribonuclease L-PSP puta; Function unclear; putative endoribonuclease, putative translation initiation inhibitor 1060068 5173557 CMM_0921 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endoribonuclease, putative translation initiation inhibitor YP_001221661.1 1059604 D 443906 CDS YP_001221662.1 148272101 5173569 complement(1060150..1062189) 1 NC_009480.1 putative acetyl-coenzyme A synthetase (Acetate-CoA ligase) (ZP_00227761.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Kineococcus radiotolerans SRS30216]; ZP_00058154.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]). pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; acetyl-coenzyme A synthetase 1062189 acsA1 5173569 acsA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetyl-coenzyme A synthetase YP_001221662.1 1060150 R 443906 CDS YP_001221663.1 148272102 5173158 1062551..1063795 1 NC_009480.1 putative ATPase (NP_787829.1| putative type II/type IV pathway secretion protein [Tropheryma whipplei str. Twist]; NP_599554.2| predicted ATPase involved in pili and flagella biosynthesis [Corynebacterium glutamicum ATCC 13032]). pfam00437, GSPII_E, Type II/IV secretion system protein. This family contains both type II and type IV pathway secretion proteins from bacteria. also VirB11 (COG0630)- similarity; Family membership; hypothetical protein 1063795 5173158 CMM_0923 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221663.1 1062551 D 443906 CDS YP_001221664.1 148272103 5173578 1063792..1064817 1 NC_009480.1 conserved membrane protein (NP_789640.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_798789.1| putative tight adherence TadC-related transmembrane protein [Vibrio parahaemolyticus RIMD 2210633]). weak similarity to: pfam00482, GSPII_F,Bacterial type II secretion system protein F domain.; Family membership; hypothetical protein 1064817 5173578 CMM_0924 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221664.1 1063792 D 443906 CDS YP_001221665.1 148272104 5173601 1064943..1065368 1 NC_009480.1 hypothetical protein (AAN24334.1| hypothetical protein BL0505 [Bifidobacterium longum NCC2705]).; hypothetical protein 1065368 5173601 CMM_0925 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221665.1 1064943 D 443906 CDS YP_001221666.1 148272105 5173641 1065365..1065766 1 NC_009480.1 hypothetical protein (AAT88406.1| hypothetical protein Lxx04030 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789638.1| hypothetical protein TW717 [Tropheryma whipplei TW08/27]); hypothetical protein 1065766 5173641 CMM_0925A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221666.1 1065365 D 443906 CDS YP_001221667.1 148272106 5173622 1065756..1066115 1 NC_009480.1 hypothetical protein (AAO44794.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein 1066115 5173622 CMM_0926 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221667.1 1065756 D 443906 CDS YP_001221668.1 148272107 5173699 1066457..1069411 1 NC_009480.1 DNA topoisomerase I (ZP_00227140.1| COG0550: Topoisomerase IA [Kineococcus radiotolerans SRS30216]; NP_959359.1| TopA [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01751, Toprim, Toprim domain. This is a conserved region from DNA primase. pfam01131, Topoisom_bac, DNA topoisomerase.; High confidence in function and specificity; DNA topoisomerase I 1069411 topA 5173699 topA Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA topoisomerase I YP_001221668.1 1066457 D 443906 CDS YP_001221669.1 148272108 5173708 1069408..1070043 1 NC_009480.1 Thymidylate kinase (dTMP kinase) (Q8G6Z6|KTHY_BIFLO Thymidylate kinase (dTMP kinase); Q9RY40|KTHY_DEIRA Thymidylate kinase (dTMP kinase)). pfam02223,Thymidylate_kin, Thymidylate kinase. DTMP_kinase: thymidylate kinase; High confidence in function and specificity; hypothetical protein 1070043 tmkA 5173708 tmkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221669.1 1069408 D 443906 CDS YP_001221670.1 148272109 5175639 1070040..1071284 1 NC_009480.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1071284 holB 5175639 holB Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III subunit delta' YP_001221670.1 1070040 D 443906 CDS YP_001221671.1 148272110 5174946 1071281..1072858 1 NC_009480.1 putative proteinase (ZP_00227136.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_825801.1| putative proteinase [Streptomyces avermitilis MA-4680]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold (only weak similarity).; Conserved hypothetical protein; hypothetical protein 1072858 5174946 CMM_0930 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221671.1 1071281 D 443906 CDS YP_001221672.1 148272111 5173904 1073336..1074694 1 NC_009480.1 D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 4 precursor (NP_601895.1| D-alanyl-D-alanine carboxypeptidase [Corynebacterium glutamicum ATCC 13032]; NP_218144.1| hypothetical protein Rv3627c [Mycobacterium tuberculosis H37Rv]). Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction. PBP4: D-alanyl-D-alanine carboxypeptid pfam02113, Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family.; Function unclear; D-alanyl-D-alanine carboxypeptidase 1074694 pbpE 5173904 pbpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 D-alanyl-D-alanine carboxypeptidase YP_001221672.1 1073336 D 443906 CDS YP_001221673.1 148272112 5175529 1074759..1075349 1 NC_009480.1 putative pyrazinamidase/nicotinamidase (CAA17257.1| PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) [Mycobacterium tuberculosis H37Rv]; NP_787820.1| pyrazinamidase; nicotinamidase [Tropheryma whipplei str. Twist])., ,pfam00857, Isochorismatase, Isochorismatase family. This family are hydrolase enzymes.; Specificity unclear; putative pyrazinamidase / nicotinamidase 1075349 pncA 5175529 pncA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyrazinamidase / nicotinamidase YP_001221673.1 1074759 D 443906 CDS YP_001221674.1 148272113 5173378 1075427..1076902 1 NC_009480.1 putative succinate-semialdehyde dehydrogenase [NADP+] (ZP_00293214.1| COG1012: NAD-dependent aldehyde dehydrogenases [Thermobifida fusca]; YP_054797.1| aldehyde dehydrogenase [Propionibacterium acnes KPA171202]). pfam00171, Aldedh, Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; High confidence in function and specificity; putative succinate-semialdehyde dehydrogenase 1076902 gabD 5173378 gabD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative succinate-semialdehyde dehydrogenase YP_001221674.1 1075427 D 443906 CDS YP_001221675.1 148272114 5174506 1076902..1077702 1 NC_009480.1 putative tRNA/rRNA methyltransferase (YP_062139.1| rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056231.1| rRNA methylase family protein [Propionibacterium acnes KPA171202]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. InterPro: tRNA/rRNA methyltransferase (SpoU).; Function unclear; putative tRNA/rRNA methyltransferase 1077702 5174506 CMM_0934 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tRNA/rRNA methyltransferase YP_001221675.1 1076902 D 443906 CDS YP_001221676.1 148272115 5173766 1077769..1078116 1 NC_009480.1 hypothetical protein (NP_895470.1| conserved hypothetical protein [Prochlorococcus marinus str. MIT 9313]; NP_898274.1| conserved hypothetical [Synechococcus sp. WH 8102]).; hypothetical protein 1078116 5173766 CMM_0935 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221676.1 1077769 D 443906 CDS YP_001221677.1 148272116 5173685 1078250..1078618 1 NC_009480.1 hypothetical protein (NP_895470.1| conserved hypothetical protein [Prochlorococcus marinus str. MIT 9313]; NP_898274.1| conserved hypothetical [Synechococcus sp. WH 8102]).; hypothetical protein 1078618 5173685 CMM_0936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221677.1 1078250 D 443906 CDS YP_001221678.1 148272117 5173774 complement(1078702..1080633) 1 NC_009480.1 putative multidrug export ABC transporter, fused permease and ATP-binding protein (YP_061527.1| ABC transporter, NBP/MSD fusion protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627447.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). pfam00664, ABC_membrane,ABC transporter transmembrane region. pfam00005, ABC_tran,ABC transporter.; Function unclear; putative multidrug export ABC transporter, fused permease and ATP-binding protein 1080633 5173774 CMM_0937 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug export ABC transporter, fused permease and ATP-binding protein YP_001221678.1 1078702 R 443906 CDS YP_001221679.1 148272118 5173744 1080838..1081764 1 NC_009480.1 putative multidrug export ABC transporter, ATP-binding protein (ZP_00199970.1| COG1131: ABC-type multidrug transport system, ATPase component [Rubrobacter xylanophilus DSM 9941]; CAH04372.1| NodI membrane transport protein [Sinorhizobium sp. BR816]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative multidrug export ABC transporter, ATP-binding protein 1081764 5173744 CMM_0938 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug export ABC transporter, ATP-binding protein YP_001221679.1 1080838 D 443906 CDS YP_001221680.1 148272119 5173831 1081761..1082594 1 NC_009480.1 putative multidrug export ABC transporter, permease component (NP_435717.1| NodJ membrane transport protein [Sinorhizobium meliloti 1021]; ZP_00271835.1| COG0842: ABC-type multidrug transport system, permease component [Ralstonia metallidurans CH34]). pfam01061, ABC2_membrane,ABC-2 type transporter.; Function unclear; putative multidrug export ABC transporter,permease component 1082594 5173831 CMM_0939 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug export ABC transporter,permease component YP_001221680.1 1081761 D 443906 CDS YP_001221681.1 148272120 5173803 1082591..1083433 1 NC_009480.1 putative multidrug export ABC transporter, permease component (ZP_00329441.1| COG0842: ABC-type multidrug transport system, permease component [Moorella thermoacetica ATCC 39073]; ZP_00291807.1| COG0842: ABC-type multidrug transport system, permease component [Thermobifida fusca]). pfam01061, ABC2_membrane, ABC-2 type transporter.; Specificity unclear; putative multidrug export ABC transporter,permease component 1083433 5173803 CMM_0940 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug export ABC transporter,permease component YP_001221681.1 1082591 D 443906 CDS YP_001221682.1 148272121 5173870 complement(1083396..1084745) 1 NC_009480.1 putative MFS permease (NP_530800.1| MFS permease [Agrobacterium tumefaciens str. C58]; ZP_00195331.1| COG0477: Permeases of the major facilitator superfamily [Mesorhizobium sp. BNC1]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894). This family consists of several bacterial proteins, many of which are annotated as putative transmembrane transport proteins.; Specificity unclear; MFS family transporter 1084745 5173870 CMM_0941 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MFS family transporter YP_001221682.1 1083396 R 443906 CDS YP_001221683.1 148272122 5173893 1084888..1085718 1 NC_009480.1 putative ribokinase (ZP_00019960.1| hypothetical protein [Chloroflexus aurantiacus]; NP_781564.1| ribokinase [Clostridium tetani E88]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; hypothetical protein 1085718 5173893 CMM_0942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221683.1 1084888 D 443906 CDS YP_001221684.1 148272123 5173938 1085724..1086191 1 NC_009480.1 hypothetical protein 1086191 5173938 CMM_0943 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221684.1 1085724 D 443906 CDS YP_001221685.1 148272124 5173962 1086418..1087686 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (NP_637562.1| ABC transporter sugar binding protein [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00233263.1| ABC transporter, substrate-binding protein [Listeria monocytogenes str. 1/2a F6854]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 1087686 5173962 CMM_0944 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001221685.1 1086418 D 443906 CDS YP_001221686.1 148272125 5174005 1087690..1088631 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_779660.1| ABC transporter sugar permease [Xylella fastidiosa Temecula1]; AAM24057.1| ABC-type sugar transport systems, permease components [Thermoanaerobacter tengcongensis MB4]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 1088631 5174005 CMM_0945 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221686.1 1087690 D 443906 CDS YP_001221687.1 148272126 5173976 1088643..1089554 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_471178.1| ; NP_694344.1| sugar binding-protein dependent transporter system permease [Oceanobacillus iheyensis HTE831]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 1089554 5173976 CMM_0946 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221687.1 1088643 D 443906 CDS YP_001221688.1 148272127 5174078 1089587..1091449 1 NC_009480.1 putative beta-glycosidase (EAA49874.1| hypothetical protein MG10038.4 [Magnaporthe grisea 70-15]; CAD47965.1| putative beta-glucosidase [Arthrobacter nicotinovorans]; ZP_00214214.1| COG1472: Beta-glucosidase-related glycosidases [Burkholderia cepacia R18194]). pfam00933,Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915, Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain.sim; Specificity unclear; putative beta-glycosidase 1091449 5174078 CMM_0947 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glycosidase YP_001221688.1 1089587 D 443906 CDS YP_001221689.1 148272128 5174028 1091558..1092697 1 NC_009480.1 puative transcriptional regulator, LacI family (Q45831|REGA_CLOSA HTH-type transcriptional regulator regA; ZP_00186316.1| COG1609: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]). pfam00356, LacI,Bacterial regulatory proteins, lacI family. pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator 1092697 5174028 CMM_0948 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001221689.1 1091558 D 443906 CDS YP_001221690.1 148272129 5174135 complement(1092708..1092917) 1 NC_009480.1 Hypothetical protein; hypothetical protein 1092917 5174135 CMM_0949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221690.1 1092708 R 443906 CDS YP_001221691.1 148272130 5174041 complement(1092917..1093471) 1 NC_009480.1 conserved hypothetical protein (ZP_00141347.1| COG2258: Uncharacterized protein conserved in bacteria [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00189460.2| COG2258: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam03473, MOSC,MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes.; Function unclear; hypothetical protein 1093471 5174041 CMM_0950 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221691.1 1092917 R 443906 CDS YP_001221692.1 148272131 5174171 1093591..1094295 1 NC_009480.1 Hypothetical protein; hypothetical protein 1094295 5174171 CMM_0951 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221692.1 1093591 D 443906 CDS YP_001221693.1 148272132 5174098 complement(1094342..1095748) 1 NC_009480.1 putative MFS permease (NP_629604.1| transmembrane transport protein [Streptomyces coelicolor A3(2)]; NP_386279.1| PUTATIVE TRANSPORT TRANSMEMBRANE PROTEIN [Sinorhizobium meliloti]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease 1095748 5174098 CMM_0952 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221693.1 1094342 R 443906 CDS YP_001221694.1 148272133 5174243 complement(1095854..1097269) 1 NC_009480.1 putative MFS permease (NP_629604.1| transmembrane transport protein [Streptomyces coelicolor A3(2)]; NP_695723.1| transmembrane transport protein possibly for shikimate [Bifidobacterium longum NCC2705]). pfam00083,Sugar_tr, Sugar (and other) transporter. 2A0106: citrate-proton symport; Specificity unclear; putative MFS permease 1097269 5174243 CMM_0953 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221694.1 1095854 R 443906 CDS YP_001221695.1 148272134 5174206 1097486..1097782 1 NC_009480.1 hypothetical protein 1097782 5174206 CMM_0954 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221695.1 1097486 D 443906 CDS YP_001221696.1 148272135 5174285 complement(1097779..1099572) 1 NC_009480.1 putative peptide ABC transporter, permease compound (NP_630721.1| putative transport system permease protein [Streptomyces coelicolor A3(2)]; YP_049650.1| putative transport system membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]). two fused permease domains (COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components and COG1173, DppC,ABC-type dipeptide/oligopeptide/nickel transport systems,permease components).; Specificity unclear; putative peptide ABC transporter, permease compound 1099572 5174285 CMM_0955 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease compound YP_001221696.1 1097779 R 443906 CDS YP_001221697.1 148272136 5174300 complement(1099572..1101113) 1 NC_009480.1 putative peptide ABC transporter, binding protein (YP_049651.1| putative ABC transporter substrate-binding protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_630720.1| putative solute-binding lipoprotein [Streptomyces coelicolor A3(2)]). pfam00496, SBP_bac_5,Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 1101113 5174300 CMM_0956 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001221697.1 1099572 R 443906 CDS YP_001221698.1 148272137 5174357 complement(1101103..1102527) 1 NC_009480.1 putative MFS permease (YP_049652.1| putative transport system membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00226985.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083,Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters 2A0115: benzoate transport; Specificity unclear; putative MFS permease 1102527 5174357 CMM_0957 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221698.1 1101103 R 443906 CDS YP_001221699.1 148272138 5174403 complement(1102524..1103351) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_943428.1| ABC transporter, ATP-binding protin [Klebsiella pneumoniae]; AAP21664.1| Shy17 [Streptomyces hygroscopicus subsp. yingchengensis]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 1103351 5174403 CMM_0958 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001221699.1 1102524 R 443906 CDS YP_001221700.1 148272139 5174459 complement(1103348..1104208) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_244513.1| oligopeptide ABC transporter (ATP-binding protein) [Bacillus halodurans]; NP_693374.1| oligopeptide ABC transporter ATP-binding protein [Oceanobacillus iheyensis HTE831]). pfam00005, ABC_tran,ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 1104208 5174459 CMM_0959 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001221700.1 1103348 R 443906 CDS YP_001221701.1 148272140 5174431 complement(1104310..1104792) 1 NC_009480.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1104792 ribH 5174431 ribH Clavibacter michiganensis subsp. michiganensis NCPPB 382 6,7-dimethyl-8-ribityllumazine synthase YP_001221701.1 1104310 R 443906 CDS YP_001221702.1 148272141 5174053 complement(1104789..1106123) 1 NC_009480.1 Riboflavin biosynthesis protein ribA [Includes: GTP cyclohydrolase II (EC 3.5.4.25) and 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase)] (YP_061534.1| GTP cyclohydrolase II; 3,4-dihydroxy- 2-butanone-4-phosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_293879.1| GTP cyclohydrolase II/3,4-dihydroxy- 2-butanone-4-phosphate synthase [Deinococcus radiodurans R1]). contains two domains: N-terminal,pfam00926, DHBP_synthase, 3,4-dihydroxy-2-butanone 4-phosphate synthase. C-terminal, COG0807, RibA, GTP cyclohydrolase II [Coenzyme metabolism], pfam00925,GTP_cyclohydro2, GTP cyclohydrolase II.; High confidence in function and specificity; 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II 1106123 ribAB 5174053 ribAB Clavibacter michiganensis subsp. michiganensis NCPPB 382 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II YP_001221702.1 1104789 R 443906 CDS YP_001221703.1 148272142 5174207 complement(1106120..1106776) 1 NC_009480.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1106776 ribC 5174207 ribC Clavibacter michiganensis subsp. michiganensis NCPPB 382 riboflavin synthase subunit alpha YP_001221703.1 1106120 R 443906 CDS YP_001221704.1 148272143 5174955 complement(1106776..1107846) 1 NC_009480.1 Riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (EC 3.5.4.26) (Riboflavin-specific deaminase) and 5-amino-6-(5-phosphoribosylamino) uracil reductase (EC 1.1.1.193) (HTP reductase)] (YP_061536.1| riboflavin-specific deaminase; riboflavin-specific reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_855096.1| PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin- specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase) [Mycobacterium bovis AF2122/97]). contains two domains: N-terminally, COG0117, RibD, Pyrimidine deaminase [Coenzyme metabolism]; pfam00383, dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region. C-terminally, COG1985, RibD, Pyrimidine reductase,riboflavin biosynthesis [Coenzyme metabolism]; pfam01872,RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis.; High confidence in function and specificity; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase 1107846 ribD 5174955 ribD Clavibacter michiganensis subsp. michiganensis NCPPB 382 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001221704.1 1106776 R 443906 CDS YP_001221705.1 148272144 5175554 complement(1108127..1108891) 1 NC_009480.1 putative hydrolase (NP_629683.1| putative hydrolase [Streptomyces coelicolor A3(2)]; ZP_00191679.2| COG1011: Predicted hydrolase (HAD superfamily) [Kineococcus radiotolerans SRS30216]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Function unclear; putative hydrolase 1108891 5175554 CMM_0964 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221705.1 1108127 R 443906 CDS YP_001221706.1 148272145 5174597 complement(1108888..1109901) 1 NC_009480.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1109901 trpS 5174597 trpS Clavibacter michiganensis subsp. michiganensis NCPPB 382 tryptophanyl-tRNA synthetase YP_001221706.1 1108888 R 443906 CDS YP_001221707.1 148272146 5173922 complement(1109984..1110829) 1 NC_009480.1 putative exonuclease III (NP_787813.1| putative exodeoxyribonuclease [Tropheryma whipplei str. Twist]; ZP_00198614.2| COG0708: Exonuclease III [Kineococcus radiotolerans SRS30216]). pfam03372, Exo_endo_phos,Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; High confidence in function and specificity; putative exonuclease III 1110829 xthA 5173922 xthA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative exonuclease III YP_001221707.1 1109984 R 443906 CDS YP_001221708.1 148272147 5174361 complement(1110840..1111949) 1 NC_009480.1 conserved membrane protein, putative ribonuclease (ZP_00121873.1| COG1295: Predicted membrane protein [Bifidobacterium longum DJO10A]; NP_599910.1| multiple transmembrane domain containing protein [Corynebacterium glutamicum ATCC 13032]). pfam03631, Ribonuclease_BN,Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation.; Function unclear; membrane protein, putative ribonuclease 1111949 5174361 CMM_0967 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative ribonuclease YP_001221708.1 1110840 R 443906 CDS YP_001221709.1 148272148 5174481 1112074..1113729 1 NC_009480.1 Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, EI component) (NP_828150.1| putative phosphoenolpyruvate- protein phosphotransferase [Streptomyces avermitilis MA-4680]; ZP_00293042.1| COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Thermobifida fusca]). pfam05524,PEP-utilisers_N, PEP-utilising enzyme, N-terminal. pfam00391, PEP-utilizers, PEP-utilising enzyme, mobile domain. pfam02896, PEP-utilizers_C, PEP-utilising enzyme,TIM barrel domain. InterPro: PEP-utilizing enzyme.; Specificity unclear; phosphoenolpyruvate--protein phosphatase 1113729 ptsA 5174481 ptsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoenolpyruvate--protein phosphatase YP_001221709.1 1112074 D 443906 CDS YP_001221710.1 148272149 5174833 complement(1113818..1114579) 1 NC_009480.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1114579 sdhB 5174833 sdhB Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinate dehydrogenase iron-sulfur subunit YP_001221710.1 1113818 R 443906 CDS YP_001221711.1 148272150 5174839 complement(1114637..1116460) 1 NC_009480.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1116460 sdhA 5174839 sdhA Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinate dehydrogenase flavoprotein subunit YP_001221711.1 1114637 R 443906 CDS YP_001221712.1 148272151 5174643 complement(1116493..1116957) 1 NC_009480.1 succinate dehydrogenase, hydrophobic membrane subunit (YP_061549.1| succinate dehydrogenase, membrane subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225992.1| COG2142: Succinate dehydrogenase,hydrophobic anchor subunit [Kineococcus radiotolerans SRS30216]). pfam01127, Sdh_cyt, Succinate dehydrogenase cytochrome b subunit.; High confidence in function and specificity; putative succinate dehydrogenase, hydrophobic membrane subunit 1116957 sdhD 5174643 sdhD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative succinate dehydrogenase, hydrophobic membrane subunit YP_001221712.1 1116493 R 443906 CDS YP_001221713.1 148272152 5174191 complement(1116960..1117394) 1 NC_009480.1 succinate dehydrogenase, cytochrome b subunit (NP_629013.1| putative succinate dehydrogenase membrane subunit [Streptomyces coelicolor A3(2)]; ZP_00225993.1| COG2009: Succinate dehydrogenase/fumarate reductase,cytochrome b subunit [Kineococcus radiotolerans SRS30216]). MONO-HEME CYTOCHROME OF THE SUCCINATE DEHYDROGENASE COMPLEX. pfam01127, Sdh_cyt, Succinate dehydrogenase cytochrome b subunit.; High confidence in function and specificity; succinate dehydrogenase, cytochrome b subunit 1117394 sdhC 5174191 sdhC Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinate dehydrogenase, cytochrome b subunit YP_001221713.1 1116960 R 443906 CDS YP_001221714.1 148272153 5175055 complement(1117535..1118728) 1 NC_009480.1 putative mannosyl transferase (CAB08968.1| MANNOSYLTRANSFERASE PIMB [Mycobacterium tuberculosis H37Rv]; NP_737090.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). InterPro: Glycosyl transferases group 1. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative mannosyl transferase 1118728 5175055 CMM_0973 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mannosyl transferase YP_001221714.1 1117535 R 443906 CDS YP_001221715.1 148272154 5174534 1118828..1119949 1 NC_009480.1 Mannose-1-phosphate guanylyltransferase (NP_787484.1| Mannose-1-phosphate guanylyltransferase [Tropheryma whipplei str. Twist]; ZP_00225994.1| COG0836: Mannose-1-phosphate guanylyltransferase [Kineococcus radiotolerans SRS30216]). INVOLVED IN GDP-MANNOSE BIOSYNTHESIS WHICH SERVES AS THE ACTIVATED SUGAR NUCLEOTIDE PRECURSOR FOR MANNOSE RESIDUES IN CELL SURFACE POLYSACCHARIDES. InterPro: ADP-glucose pyrophosphorylase. pfam00483, NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; hypothetical protein 1119949 manC 5174534 manC Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221715.1 1118828 D 443906 CDS YP_001221716.1 148272155 5175172 1120024..1121097 1 NC_009480.1 putative ABC transporter, substrate-binding protein (ZP_00225996.1| COG1744: Uncharacterized ABC-type transport system, periplasmic component/ surface lipoprotein [Kineococcus radiotolerans SRS30216]; NP_622136.1| Surface lipoprotein [Thermoanaerobacter tengcongensis]). pfam02608, Bmp, Basic membrane protein. This is a family of basic membrane lipoproteins form Borrelia and various putative lipoproteins form other bacteria.; Function unclear; putative ABC transporter, substrate-binding protein 1121097 5175172 CMM_0975 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, substrate-binding protein YP_001221716.1 1120024 D 443906 CDS YP_001221717.1 148272156 5174663 1121248..1122342 1 NC_009480.1 putative ABC transporter, substrate-binding protein (ZP_00225996.1| COG1744: Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [Kineococcus radiotolerans SRS30216]; NP_622136.1| Surface lipoprotein [Thermoanaerobacter tengcongensis]). pfam02608, Bmp, Basic membrane protein. This is a family of basic membrane lipoproteins form Borrelia and various putative lipoproteins form other bacteria. InterPro: Basic membrane lipoprotein.; Function unclear; putative ABC transporter, substrate-binding protein 1122342 5174663 CMM_0976 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, substrate-binding protein YP_001221717.1 1121248 D 443906 CDS YP_001221718.1 148272157 5174615 1122424..1123965 1 NC_009480.1 putative sugar ABC transporter, ATPase component (ZP_00225997.1| COG3845: ABC-type uncharacterized transport systems, ATPase components [Kineococcus radiotolerans SRS30216]; NP_622137.1| ABC-type sugar (aldose) transport system, ATPase component [Thermoanaerobacter tengcongensis]). pfam00005, ABC_tran,ABC transporter (duplicated).; Specificity unclear; putative sugar ABC transporter, ATPase component 1123965 5174615 CMM_0977 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATPase component YP_001221718.1 1122424 D 443906 CDS YP_001221719.1 148272158 5174742 1123962..1125338 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00198294.1| COG4603: ABC-type uncharacterized transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00330811.1| COG4603: ABC-type uncharacterized transport system, permease component [Moorella thermoacetica ATCC 39073]). pfam02653,BPD_transp_2, Branched-chain amino acid transport system / permease component. This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system. InterPro: Binding-system dependent bacterial transporters (araH livH/limM families).; Specificity unclear; putative sugar ABC transporter, permease component 1125338 5174742 CMM_0978 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221719.1 1123962 D 443906 CDS YP_001221720.1 148272159 5174700 1125335..1126639 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00226022.1| COG1079: Uncharacterized ABC-type transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00108155.1| COG1079: Uncharacterized ABC-type transport system, permease component [Nostoc punctiforme]). pfam02653, BPD_transp_2,Branched-chain amino acid transport system / permease component. This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease, and a ribose transport system.; Specificity unclear; putative sugar ABC transporter, permease component 1126639 5174700 CMM_0979 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221720.1 1125335 D 443906 CDS YP_001221721.1 148272160 5174808 1126645..1127067 1 NC_009480.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1127067 cddA 5174808 cddA Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytidine deaminase YP_001221721.1 1126645 D 443906 CDS YP_001221722.1 148272161 5175072 1127064..1128362 1 NC_009480.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 1128362 deoA 5175072 deoA Clavibacter michiganensis subsp. michiganensis NCPPB 382 thymidine phosphorylase YP_001221722.1 1127064 D 443906 CDS YP_001221723.1 148272162 5174567 complement(1128418..1129353) 1 NC_009480.1 Inosine-uridine nucleoside N-ribohydrolase (Purine nucleosidase) (NP_738092.1| putative nucleoside hydrolase [Corynebacterium efficiens YS-314]; NP_246706.1| IunH [Pasteurella multocida Pm70]). CATALYZES THE HYDROLYSIS OF ALL OF THE COMMONLY OCCURRING PURINE AND PYRIMIDINE NUCLEOSIDES INTO RIBOSE AND THE ASSOCIATED BASE BUT HAS A PREFERENCE FOR INOSINE AND URIDINE AS SUBSTRATES. pfam01156, IU_nuc_hydro, Inosine-uridine preferring nucleoside hydrolase.; High confidence in function and specificity; inosine-uridine preferring nucleoside hydrolase 1129353 iunH 5174567 iunH Clavibacter michiganensis subsp. michiganensis NCPPB 382 inosine-uridine preferring nucleoside hydrolase YP_001221723.1 1128418 R 443906 CDS YP_001221724.1 148272163 5173704 1129456..1130574 1 NC_009480.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1130574 addA 5173704 addA Clavibacter michiganensis subsp. michiganensis NCPPB 382 adenosine deaminase YP_001221724.1 1129456 D 443906 CDS YP_001221725.1 148272164 5173312 1130643..1131092 1 NC_009480.1 putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) (NP_694338.1| hypothetical protein OB3416 [Oceanobacillus iheyensis HTE831]; NP_463246.1| putative PTS enzyme II [Salmonella typhimurium LT2]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.; Specificity unclear; phosphotransferase system mannitol/fructose-specific IIA component 1131092 5173312 CMM_0984 Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphotransferase system mannitol/fructose-specific IIA component YP_001221725.1 1130643 D 443906 CDS YP_001221726.1 148272165 5174282 1131089..1131361 1 NC_009480.1 putative phosphotransferase system, IIB component (ZP_00234701.1| PTS system, lactose/cellobiose specific IIB subunit [Listeria monocytogenes str. 1/2a F6854]; NP_979285.1| PTS system, lactose/cellobiose specific IIB subunit [Bacillus cereus ATCC 10987]). , pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; hypothetical protein 1131361 5174282 CMM_0985 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221726.1 1131089 D 443906 CDS YP_001221727.1 148272166 5174966 complement(1131310..1132320) 1 NC_009480.1 putative membrane protein (ZP_00226020.1| hypothetical protein Krad06004090 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1132320 5174966 CMM_0986 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221727.1 1131310 R 443906 CDS YP_001221728.1 148272167 5174764 complement(1132317..1132943) 1 NC_009480.1 transcriptional regulator, MerR family (ZP_00227809.1| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00057612.1| COG0789: Predicted transcriptional regulators [Thermobifida fusca]). smart00422, HTH_MERR,helix_turn_helix, mercury resistance; Specificity unclear; MerR family transcriptional regulator 1132943 5174764 CMM_0987 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MerR family transcriptional regulator YP_001221728.1 1132317 R 443906 CDS YP_001221729.1 148272168 5174979 complement(1133031..1134734) 1 NC_009480.1 putative phosphomannomutase (NP_873912.1| probable phosphomannomutase [Haemophilus ducreyi 35000HP]; NP_246011.1| YhxB [Pasteurella multocida]). pfam02878,PGM_PMM_I, Phosphoglucomutase/phosphomannomutase,alpha/beta/alpha domain I. pfam02879, PGM_PMM_II,Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II. pfam00408, PGM_PMM_IV,Phosphoglucomutase/phosphomannomutase, C-terminal domain.; High confidence in function and specificity; putative phosphomannomutase 1134734 manB 5174979 manB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphomannomutase YP_001221729.1 1133031 R 443906 CDS YP_001221730.1 148272169 5175780 complement(1134731..1135558) 1 NC_009480.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1135558 punA 5175780 punA Clavibacter michiganensis subsp. michiganensis NCPPB 382 purine nucleoside phosphorylase YP_001221730.1 1134731 R 443906 CDS YP_001221731.1 148272170 5175365 1135649..1137091 1 NC_009480.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; flavoprotein disulfide reductase 1137091 lpdA 5175365 lpdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 flavoprotein disulfide reductase YP_001221731.1 1135649 D 443906 CDS YP_001221732.1 148272171 5173672 complement(1137170..1138939) 1 NC_009480.1 Acetyl-/propionyl-coenzyme A carboxylase alpha chain [Includes: Biotin carboxylase (EC 6.3.4.14); Biotin carboxyl carrier protein (BCCP)] (ZP_00293824.1| COG4770: Acetyl/propionyl-CoA carboxylase, alpha subunit [Thermobifida fusca]; NP_629074.1| putative acyl-CoA carboxylase complex A subunit [Streptomyces coelicolor A3(2)]). THIS PROTEIN CARRIES TWO FUNCTIONS: BIOTIN CARBOXYL CARRIER PROTEIN AND BIOTIN CARBOXYLTRANSFERASE. accC: acetyl-CoA carboxylase biotin c pfam00289,CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain. pfam02786, CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain. pfam02785,Biotin_carb_C, Biotin carboxylase C-terminal domain. pfam00364, Biotin_lipoyl, Biotin-requiring enzyme.; High confidence in function and specificity; acetyl/propionyl CoA carboxylase subunit 1138939 accA 5173672 accA Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetyl/propionyl CoA carboxylase subunit YP_001221732.1 1137170 R 443906 CDS YP_001221733.1 148272172 5173449 1139062..1139589 1 NC_009480.1 hypothetical protein 1139589 5173449 CMM_0992 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221733.1 1139062 D 443906 CDS YP_001221734.1 148272173 5174869 complement(1139611..1140282) 1 NC_009480.1 putative inhibitor of septum formation (ZP_00049215.1| COG0424: Nucleotide-binding protein implicated in inhibition of septum formation [Magnetospirillum magnetotacticum]; ZP_00226343.1| COG0424: Nucleotide-binding protein implicated in inhibition of septum formation [Kineococcus radiotolerans SRS30216]). pfam02545, Maf, Maf-like protein. Maf is a putative inhibitor of septum formation in eukaryotes,bacteria, and archaea.; High confidence in function and specificity; hypothetical protein 1140282 5174869 CMM_0993 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221734.1 1139611 R 443906 CDS YP_001221735.1 148272174 5175063 1140337..1141602 1 NC_009480.1 putative RNA methyltransferase (ZP_00294131.1| COG2265: SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Thermobifida fusca]; ZP_00226682.1| COG2265: SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Kineococcus radiotolerans SRS30216]). pfam01938, TRAM, TRAM domain. This small domain has no known function. However it may perform a nucleic acid binding role. pfam05958, tRNA_U5-meth_tr, tRNA (Uracil-5-)-methyltransferase.; Specificity unclear; putative RNA methyltransferase 1141602 5175063 CMM_0994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNA methyltransferase YP_001221735.1 1140337 D 443906 CDS YP_001221736.1 148272175 5175025 1141702..1142406 1 NC_009480.1 putative two component system, response regulator (NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]; AAP42850.1| NanT3 [Streptomyces nanchangensis]). InterPro: Response regulator receiver domain pfam00072, Response_reg,Response regulator receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two component system, response regulator 1142406 5175025 CMM_0995 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two component system, response regulator YP_001221736.1 1141702 D 443906 CDS YP_001221737.1 148272176 5175096 1142396..1143742 1 NC_009480.1 putative two-component system, sensor kinase (ZP_00121793.2| COG4585: Signal transduction histidine kinase [Bifidobacterium longum DJO10A]; AAP42852.1| NanT5 [Streptomyces nanchangensis]). pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1143742 5175096 CMM_0996 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001221737.1 1142396 D 443906 CDS YP_001221738.1 148272177 5175114 1143739..1144761 1 NC_009480.1 Hypothetical protein; hypothetical protein 1144761 5175114 CMM_0997 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221738.1 1143739 D 443906 CDS YP_001221739.1 148272178 5175150 complement(1145049..1145282) 1 NC_009480.1 hypothetical protein (YP_056397.1| hypothetical protein PPA1708 [Propionibacterium acnes KPA171202]; NP_962334.1| hypothetical protein MAP3400 [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 1145282 5175150 CMM_0998 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221739.1 1145049 R 443906 CDS YP_001221740.1 148272179 5175179 complement(1145279..1146892) 1 NC_009480.1 putative acetyl-/propionyl-CoA carboxylase beta chain (NP_629079.1| propionyl-CoA carboxylase complex B subunit [Streptomyces coelicolor A3(2)]; ZP_00293826.1| COG4799: Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Thermobifida fusca]). pfam01039, Carboxyl_trans, Carboxyl transferase domain. All of the members in this family are biotin dependent carboxylases.; Specificity unclear; putative acetyl/propionyl-CoA carboxylase beta chain 1146892 accD 5175179 accD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyl/propionyl-CoA carboxylase beta chain YP_001221740.1 1145279 R 443906 CDS YP_001221741.1 148272180 5173471 1147000..1147782 1 NC_009480.1 putative lipoate protein ligase (NP_788981.1| putative protein ligase [Tropheryma whipplei TW08/27]; NP_599941.1| biotin-(acetyl-CoA carboxylase) ligase [Corynebacterium glutamicum ATCC 13032]). pfam03099,BPL_LipA_LipB, Biotin/lipoate A/B protein ligase family. pfam02237, BPL_C, Biotin protein ligase C terminal domain. birA_ligase: biotin--acetyl-CoA-carboxyla; Specificity unclear; putative lipoate protein ligase 1147782 5173471 CMM_1000 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lipoate protein ligase YP_001221741.1 1147000 D 443906 CDS YP_001221742.1 148272181 5175266 1147786..1148580 1 NC_009480.1 hypothetical membrane protein pfam03703, DUF304,Bacterial membrane flanked domain.; Hypothetical protein; hypothetical protein 1148580 5175266 CMM_1001 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221742.1 1147786 D 443906 CDS YP_001221743.1 148272182 5175195 complement(1148600..1149118) 1 NC_009480.1 putative membrane protein (NP_301574.1| putative membrane protein [Mycobacterium leprae TN]; ZP_00293833.1| COG2246: Predicted membrane protein [Thermobifida fusca]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Function unclear; hypothetical protein 1149118 5175195 CMM_1002 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221743.1 1148600 R 443906 CDS YP_001221744.1 148272183 5175417 1149255..1150382 1 NC_009480.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1150382 purK 5175417 purK Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_001221744.1 1149255 D 443906 CDS YP_001221745.1 148272184 5173237 1150437..1150961 1 NC_009480.1 Phosphoribosylaminoimidazole carboxylase catalytic subunit (O67239|PUR6_AQUAE Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); ZP_00226348.1| COG0041: Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Kineococcus radiotolerans SRS30216]; pfam00731, AIRC,AIR carboxylase. Members of this family catalyse the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyse the sixth step of de novo purine biosynthesis. InterPro: 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; High confidence in function and specificity; phosphoribosylaminoimidazole carboxylase catalytic subunit 1150961 purE 5173237 purE Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_001221745.1 1150437 D 443906 CDS YP_001221746.1 148272185 5175348 1150958..1152307 1 NC_009480.1 putative transcriptional regulator (ZP_00292832.1| COG1316: Transcriptional regulator [Thermobifida fusca]). pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain. InterPro: Cell envelope-related transcriptional attenuator domain.; Function unclear; putative transcriptional regulator 1152307 5175348 CMM_1005 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001221746.1 1150958 D 443906 CDS YP_001221747.1 148272186 5175314 complement(1152323..1153507) 1 NC_009480.1 putative glycosyltransferase, mannosyltransferase (YP_061577.1| mannosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; AAS55730.1| putative glycosyl transferase [Aneurinibacillus thermoaerophilus]; I76776 O9 mannan biosynthesis mannosyltransferase (EC 2.4.1.-) B - Escherichia coli). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase,mannosyltransferase 1153507 wcqB 5175314 wcqB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase,mannosyltransferase YP_001221747.1 1152323 R 443906 CDS YP_001221748.1 148272187 5173560 complement(1153554..1154300) 1 NC_009480.1 putative polysaccharide ABC transporter, ATP-binding protein (ZP_00226434.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_787162.1| ABC transporter ATP-binding protein [Tropheryma whipplei str. Twist]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative polysaccharide ABC transporter, ATP-binding protein 1154300 wzt 5173560 wzt Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polysaccharide ABC transporter, ATP-binding protein YP_001221748.1 1153554 R 443906 CDS YP_001221749.1 148272188 5173960 complement(1154284..1155153) 1 NC_009480.1 putative polysaccharide ABC-transporter, permease component (ZP_00226433.1| COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component [Kineococcus radiotolerans SRS30216]; NP_788992.1| putative ABC transport integral membrane subunit [Tropheryma whipplei TW08/27]). pfam01061,ABC2_membrane, ABC-2 type transporter.; Specificity unclear; putative polysaccharide ABC-transporter,permease component 1155153 wzm 5173960 wzm Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polysaccharide ABC-transporter,permease component YP_001221749.1 1154284 R 443906 CDS YP_001221750.1 148272189 5173842 complement(1155248..1156102) 1 NC_009480.1 putative dTDP-4-dehydrorhamnose reductase (dTDP-L-rhamnose synthetase) (YP_061578.1| dTDP-4-dehydrorhamnose reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787157.1| dTDP-4-dehydrorhamnose reductase [Tropheryma whipplei str. Twist]; AAG29801.1| dTDP-4-keto-6-deoxyhexose reductase [Streptomyces rishiriensis]). pfam04321, RmlD_sub_bind, RmlD substrate binding domain. L-rhanmose is a saccharide required for the virulence of some bacteria. Its precursor, dTDP-L-rhanmose, is synthesised by four different enzymes the final one of which is RmlD. The RmlD substrate binding domain is responsible for binding a sugar nucleotide.; High confidence in function and specificity; putative dTDP-4-dehydrorhamnose reductase 1156102 rmlD 5173842 rmlD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dTDP-4-dehydrorhamnose reductase YP_001221750.1 1155248 R 443906 CDS YP_001221751.1 148272190 5174905 complement(1156099..1157088) 1 NC_009480.1 putative dTDP-glucose 4,6-dehydratase (YP_061579.1| thymidine diphosphoglucose 4,6-dehydratase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787158.1| dTDP-glucose 4,6-dehydratase [Tropheryma whipplei str. Twist]; AAK83290.1| DTDP-glucose 4,6-dehydratase [Saccharopolyspora spinosa]). InterPro: NAD dependent epimerase/dehydratase family. pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; putative dTDP-glucose 4,6-dehydratase 1157088 rmlB 5174905 rmlB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dTDP-glucose 4,6-dehydratase YP_001221751.1 1156099 R 443906 CDS YP_001221752.1 148272191 5173940 1157269..1157721 1 NC_009480.1 conserved hypothetical protein, putative sugar translocase (NP_949391.1| hypothetical protein RPA4055 [Rhodopseudomonas palustris CGA009]; NP_790903.1| membrane protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; NP_636006.1| sugar translocase [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00231618.1| cell wall teichoic acid glycosylation protein GtcA [Listeria monocytogenes str. 4b H7858]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; putative sugar translocase 1157721 wcqC 5173940 wcqC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar translocase YP_001221752.1 1157269 D 443906 CDS YP_001221753.1 148272192 5173577 1157747..1158352 1 NC_009480.1 putative dTDP-4-dehydrorhamnose 3,5-epimerase (dTDP-L-rhamnose synthetase) (YP_061580.1| dTDP-4-dehydrorhamnose 3,5-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]; dTDP-L-rhamnose synthetase) (NP_963158.1| RmlC [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyse the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose.; High confidence in function and specificity; dTDP-4-dehydrorhamnose 3,5-epimerase 1158352 rmlC 5173577 rmlC Clavibacter michiganensis subsp. michiganensis NCPPB 382 dTDP-4-dehydrorhamnose 3,5-epimerase YP_001221753.1 1157747 D 443906 CDS YP_001221754.1 148272193 5174141 1158356..1159219 1 NC_009480.1 putative glucose-1-phosphate thymidylyltransferase (dTDP-glucose synthase) (AAN65244.1| dTDP-glucose synthase [Streptomyces roseochromogenes subsp. oscitans]; AAF67515.1| NovV [Streptomyces caeruleus]). pfam00483,NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; putative glucose-1-phosphate thymidylyltransferase 1159219 rmlA 5174141 rmlA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucose-1-phosphate thymidylyltransferase YP_001221754.1 1158356 D 443906 CDS YP_001221755.1 148272194 5174199 complement(1159283..1160260) 1 NC_009480.1 putative NDP-sugar-epimerase (AAP69596.1| putative NDP-sugar dehydratase/epimerase [Streptomyces griseoflavus]; YP_061584.1| UDP-glucose 4-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative NDP-sugar-epimerase 1160260 wcqD 5174199 wcqD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NDP-sugar-epimerase YP_001221755.1 1159283 R 443906 CDS YP_001221756.1 148272195 5173551 complement(1160257..1161288) 1 NC_009480.1 putative glycosyl transferase (NP_108629.1| ; NP_630465.1| putative sugar transferase [Streptomyces coelicolor A3(2)]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyl transferase 1161288 wcqE 5173551 wcqE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221756.1 1160257 R 443906 CDS YP_001221757.1 148272196 5173593 complement(1161285..1162139) 1 NC_009480.1 putative glycosyl transferase (NP_661812.1| glycosyl transferase [Chlorobium tepidum TLS]; AAN04247.1| putative glycosyl transferase [Streptomyces sp. 139]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyl transferase 1162139 wcqF 5173593 wcqF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221757.1 1161285 R 443906 CDS YP_001221758.1 148272197 5173617 1162412..1164625 1 NC_009480.1 hypothetical membrane protein (weak similarities,ZP_00047020.1| COG4485: Predicted membrane protein [Lactobacillus gasseri]; NP_689157.1| ABC transporter,permease protein, putative [Streptococcus agalactiae 2603V/R]). weak similarity to: COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Hypothetical protein; hypothetical protein 1164625 wcqG 5173617 wcqG Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221758.1 1162412 D 443906 CDS YP_001221759.1 148272198 5173618 1164622..1165584 1 NC_009480.1 putative glycosyl (rhamnosyl) transferase (ZP_00226429.1| COG0463: Glycosyltransferases involved in cell wall biogenesis [Kineococcus radiotolerans SRS30216]; YP_004503.1| dTDP-rhamnosyl transferase rfbF [Thermus thermophilus HB27]; NP_964886.1| hypothetical protein LJ1030 [Lactobacillus johnsonii NCC 533]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyltransferase 1165584 wcqH 5173618 wcqH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221759.1 1164622 D 443906 CDS YP_001221760.1 148272199 5173592 1165776..1166624 1 NC_009480.1 putative glycosyl transferase (NP_810558.1| putative glycosyltransferase [Bacteroides thetaiotaomicron VPI-5482]; BAA19631.1| unnamed protein product [Actinobacillus actinomycetemcomitans]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Specificity unclear; putative glycosyltransferase 1166624 wcqI 5173592 wcqI Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221760.1 1165776 D 443906 CDS YP_001221761.1 148272200 5173635 1166692..1167855 1 NC_009480.1 putative UDP-galactopyranose mutase (ZP_00226431.1| COG0562: UDP-galactopyranose mutase [Kineococcus radiotolerans SS30216]; NP_739329.1| putative UDP-galactopyranose mutase [Corynebacterium efficiens YS-314]). pfam03275, GLF, UDP-galactopyranose mutase. UDP-GALP_mutase: UDP-galactopyranose; High confidence in function and specificity; hypothetical protein 1167855 glfA 5173635 glfA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221761.1 1166692 D 443906 CDS YP_001221762.1 148272201 5175297 1167855..1169873 1 NC_009480.1 putative glycosyltransferase (ZP_00226432.1| COG1216: Predicted glycosyltransferases [Kineococcus radiotolerans SRS30216]; NP_218325.1| hypothetical protein Rv3808c [Mycobacterium tuberculosis H37Rv]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. InterPro: Glycosyl transferase family 2.; Specificity unclear; putative glycosyltransferase 1169873 wcqJ 5175297 wcqJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001221762.1 1167855 D 443906 CDS YP_001221763.1 148272202 5173625 1170018..1171847 1 NC_009480.1 putative peptidoglycan-binding protein (YP_061590.1| hemagglutinin-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696468.1| hypothetical protein BL1304 [Bifidobacterium longum NCC2705]).; Function unclear; putative secreted protein 1171847 wcqK 5173625 wcqK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001221763.1 1170018 D 443906 CDS YP_001221764.1 148272203 5173632 1172007..1172477 1 NC_009480.1 conserved membrane protein (NP_949391.1| hypothetical protein RPA4055 [Rhodopseudomonas palustris CGA009]; NP_816266.1| teichoic acid glycosylation protein, putative [Enterococcus faecalis V583]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Conserved hypothetical protein; hypothetical protein 1172477 wcqL 5173632 wcqL Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221764.1 1172007 D 443906 CDS YP_001221765.1 148272204 5173645 complement(1172505..1173797) 1 NC_009480.1 conserved membrane protein (YP_061600.1| exopolysaccharide production protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00110594.1| COG3307: Lipid A core - O-antigen ligase and related enzymes [Nostoc punctiforme]; ZP_00085768.1| COG3307: Lipid A core - O-antigen ligase and related enzymes [Pseudomonas fluorescens PfO-1]). potentially involved in export of polysaccharides (EPS/teichoic acids).; Function unclear; hypothetical protein 1173797 wcqM 5173645 wcqM Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221765.1 1172505 R 443906 CDS YP_001221766.1 148272205 5173702 complement(1173846..1175393) 1 NC_009480.1 conserved membrane protein, putative polysaccharide polymerase (YP_061601.1| exopolysaccharide production protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_419318.1| conserved hypothetical protein [Caulobacter crescentus CB15]; ZP_00085768.1| COG3307: Lipid A core -O-antigen ligase and related enzymes [Pseudomonas fluorescens PfO-1]). pfam04932, Wzy_C, O-Antigen Polymerase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria.; membrane protein, putative polysaccharide polymerase 1175393 wzy4 5173702 wzy4 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative polysaccharide polymerase YP_001221766.1 1173846 R 443906 CDS YP_001221767.1 148272206 5174059 complement(1175393..1176571) 1 NC_009480.1 putative glutaryl-CoA dehydrogenase (NP_821894.1| putative glutaryl-CoA dehydrogenase [Streptomyces avermitilis MA-4680]; NP_294274.1| glutaryl-CoA dehydrogenase, putative [Deinococcus radiodurans]). pfam02771, Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain. The N-terminal domain of Acyl-CoA dehydrogenase is an all-alpha domain. pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. Central domain of Acyl-CoA dehydrogenase has a beta-barrel fold. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.; Specificity unclear; putative glutaryl-CoA dehydrogenase 1176571 gcdH 5174059 gcdH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutaryl-CoA dehydrogenase YP_001221767.1 1175393 R 443906 CDS YP_001221768.1 148272207 5175725 1176737..1178029 1 NC_009480.1 putative mannose-6-phosphate isomerase (YP_061602.1| mannose-6-phosphate isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301594.1| putative mannose-6-phosphate isomerase [Mycobacterium leprae]). pfam01238, PMI_typeI, Phosphomannose isomerase type I. manA: mannose-6-phosphate isomerase cl; High confidence in function and specificity; putative mannose-6-phosphate isomerase 1178029 manA 5175725 manA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mannose-6-phosphate isomerase YP_001221768.1 1176737 D 443906 CDS YP_001221769.1 148272208 5175130 1178064..1179032 1 NC_009480.1 UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (YP_061604.1| UDP-glucose 4-epimerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627211.1| UDP-glucose 4-epimerase [Streptomyces coelicolor A3(2)]). InterPro: NAD dependent epimerase/dehydratase family pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; hypothetical protein 1179032 galE1 5175130 galE1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221769.1 1178064 D 443906 CDS YP_001221770.1 148272209 5174604 1179182..1179499 1 NC_009480.1 transcriptional regulator, whiB homolog (YP_061605.1| regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789077.1| WhiB-like regulatory protein [Tropheryma whipplei TW08/27]; S20912 regulatory protein whiB - Streptomyces coelicolor). pfam02467, Whib,Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.; Hypothetical protein; transcriptional regulator whiB-like protein 1179499 whiB1 5174604 whiB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator whiB-like protein YP_001221770.1 1179182 D 443906 CDS YP_001221771.1 148272210 5173772 1179593..1182670 1 NC_009480.1 putative glycosyl transferase (NP_789078.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00058546.1| COG1216: Predicted glycosyltransferases [Thermobifida fusca]). InterPro: Glycosyl transferase family 2 pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 1182670 wcqR 5173772 wcqR Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001221771.1 1179593 D 443906 CDS YP_001221772.1 148272211 5173712 1182675..1184174 1 NC_009480.1 putative secreted protein (NP_789079.1| putative secreted protein [Tropheryma whipplei TW08/27]; NP_826221.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; Function unclear; putative secreted protein 1184174 5173712 CMM_1031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001221772.1 1182675 D 443906 CDS YP_001221773.1 148272212 5175869 complement(1184261..1184704) 1 NC_009480.1 conserved hypothetical protein (YP_061607.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696177.1| hypothetical protein BL1005 [Bifidobacterium longum NCC2705]).; hypothetical protein 1184704 5175869 CMM_1032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221773.1 1184261 R 443906 CDS YP_001221774.1 148272213 5175379 1184750..1184965 1 NC_009480.1 conserved hypothetical protein (YP_061608.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00049347.1| hypothetical protein Magn022769 [Magnetospirillum magnetotacticum]; ZP_00058543.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 1184965 5175379 CMM_1033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221774.1 1184750 D 443906 CDS YP_001221775.1 148272214 5175403 1184968..1186395 1 NC_009480.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; phosphomannomutase/phosphoglucomutase 1186395 manB 5175403 manB Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphomannomutase/phosphoglucomutase YP_001221775.1 1184968 D 443906 CDS YP_001221776.1 148272215 5175848 1186485..1186817 1 NC_009480.1 conserved hypothetical protein (ZP_00227420.1| COG1937: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; CAB09730.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02583, DUF156, Uncharacterised BCR, COG1937.; Function unclear; hypothetical protein 1186817 5175848 CMM_1035 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221776.1 1186485 D 443906 CDS YP_001221777.1 148272216 5175938 1186861..1187076 1 NC_009480.1 putative copper binding protein (ZP_00227421.1| COG2608: Copper chaperone [Kineococcus radiotolerans SRS30216]; ZP_00293701.1| COG2608: Copper chaperone [Thermobifida fusca]). cd00371, HMA, Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. InterPro: Heavy-metal-associated domain TIGRFAM (TIGR00003): copper-ion-binding protein; Function unclear; putative copper binding protein 1187076 copP 5175938 copP Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative copper binding protein YP_001221777.1 1186861 D 443906 CDS YP_001221778.1 148272217 5173687 1187078..1189552 1 NC_009480.1 putative metal-transporting ATPase (AAS20130.1| metal transporter ATPase [Arthrobacter aurescens]; ZP_00227422.1| COG2217: Cation transport ATPase [Kineococcus radiotolerans SRS30216]). , cd00371, HMA,Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain contains two cysteine residues that are important in binding and transfer of metal ions, such as copper, cadmium, cobalt and zinc. , pfam00122, E1-E2_ATPase, E1-E2 ATPase. pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Specificity unclear; putative metal-transporting ATPase 1189552 copA 5173687 copA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal-transporting ATPase YP_001221778.1 1187078 D 443906 CDS YP_001221779.1 148272218 5173633 1189615..1191099 1 NC_009480.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 1191099 ahcY 5173633 ahcY Clavibacter michiganensis subsp. michiganensis NCPPB 382 S-adenosyl-L-homocysteine hydrolase YP_001221779.1 1189615 D 443906 CDS YP_001221780.1 148272219 5172938 complement(1191194..1192009) 1 NC_009480.1 conserved membrane protein (ZP_00228191.1| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]; ZP_00058535.1| COG1714: Predicted membrane protein/domain [Thermobifida fusca]). pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown.; Hypothetical protein; hypothetical protein 1192009 5172938 CMM_1039 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221780.1 1191194 R 443906 CDS YP_001221781.1 148272220 5175761 1192080..1193075 1 NC_009480.1 conserved membrane protein (ZP_00228195.1| COG1300: Uncharacterized membrane protein [Kineococcus radiotolerans SRS30216]; ZP_00058534.1| COG1300: Uncharacterized membrane protein [Thermobifida fusca]). pfam01944, DUF95, Integral membrane protein DUF95. Members of this family have several predicted transmembrane regions. The function of this family is unknown.; Function unclear; hypothetical protein 1193075 5175761 CMM_1040 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221781.1 1192080 D 443906 CDS YP_001221782.1 148272221 5175748 complement(1193129..1195615) 1 NC_009480.1 putative beta-glucosidase (glycosyl hydrolase,family3) (Beta-D- glucoside glucohydrolase) (NP_630676.1| putative beta-glucosidase [Streptomyces coelicolor A3(2)]; ZP_00019622.1| hypothetical protein [Chloroflexus aurantiacus]). pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain. pfam01915,Glyco_hydro_3_C, Glycosyl hydrolase family 3 C terminal domain. InterPro: Glycoside hydrolase family 3 C terminal; Specificity unclear; beta-glucosidase 1195615 bglK 5175748 bglK Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-glucosidase YP_001221782.1 1193129 R 443906 CDS YP_001221783.1 148272222 5173523 complement(1195669..1196949) 1 NC_009480.1 putative MFS permease (CAD47966.1| hypothetical protein [Arthrobacter nicotinovorans]; AAL78050.1| ORFB [Saccharopolyspora erythraea]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease 1196949 5173523 CMM_1042 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221783.1 1195669 R 443906 CDS YP_001221784.1 148272223 5175744 1197061..1197702 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00192310.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00126888.1| COG1309: Transcriptional regulator [Pseudomonas syringae pv. syringae B728a]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1197702 5175744 CMM_1043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221784.1 1197061 D 443906 CDS YP_001221785.1 148272224 5175719 complement(1197725..1199032) 1 NC_009480.1 conserved hypothetical protein (CAA18015.1| POSSIBLE CONSERVED MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627241.1| putative lipoprotein [Streptomyces coelicolor A3(2)]). pfam01882, DUF58,Protein of unknown function DUF58. This family of prokaryotic proteins have no known function.; Function unclear; hypothetical protein 1199032 5175719 CMM_1044 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221785.1 1197725 R 443906 CDS YP_001221786.1 148272225 5175722 complement(1199047..1200000) 1 NC_009480.1 putative regulatory protein (NP_826235.1| putative regulatory protein [Streptomyces avermitilis MA-4680]; ZP_00058532.1| COG0714: MoxR-like ATPases [Thermobifida fusca]).; Specificity unclear; putative regulatory protein 1200000 5175722 CMM_1045 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative regulatory protein YP_001221786.1 1199047 R 443906 CDS YP_001221787.1 148272226 5175731 complement(1199997..1201259) 1 NC_009480.1 conserved hypothetical protein (NP_338346.1| hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_627239.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 1201259 5175731 CMM_1046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221787.1 1199997 R 443906 CDS YP_001221788.1 148272227 5175660 complement(1201256..1201942) 1 NC_009480.1 conserved hypothetical protein (YP_061611.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826237.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). kdpC: potassium-transporting ATPase C; hypothetical protein 1201942 5175660 CMM_1047 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221788.1 1201256 R 443906 CDS YP_001221789.1 148272228 5175711 complement(1201939..1203135) 1 NC_009480.1 conserved membrane protein (YP_061612.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07] ; ZP_00225539.1| hypothetical protein Krad06004829 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 1203135 5175711 CMM_1048 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221789.1 1201939 R 443906 CDS YP_001221790.1 148272229 5175633 1203247..1203927 1 NC_009480.1 putative two-component system response regulator (YP_061613.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058528.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Thermobifida fusca]). pfam00072, Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 1203927 5175633 CMM_1049 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001221790.1 1203247 D 443906 CDS YP_001221791.1 148272230 5175688 1203932..1205566 1 NC_009480.1 putative two-component system sensor kinase (YP_061614.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627234.1| putative two-component system histidine kinase [Streptomyces coelicolor A3(2)]). pfam00672, HAMP, HAMP domain. pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 1205566 5175688 CMM_1050 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001221791.1 1203932 D 443906 CDS YP_001221792.1 148272231 5175630 1205550..1207277 1 NC_009480.1 conserved hypothetical protein (YP_061615.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056043.1| membrane spanning lipoprotein [Propionibacterium acnes KPA171202]). ogg: 8-oxoguanine DNA-glycosylase (ogg); lipoprotein LpqB 1207277 5175630 CMM_1051 Clavibacter michiganensis subsp. michiganensis NCPPB 382 lipoprotein LpqB YP_001221792.1 1205550 D 443906 CDS YP_001221793.1 148272232 5175648 1207348..1208151 1 NC_009480.1 putative amidophosphoribosyltransferase (YP_061616.1| competence protein F [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056042.1| putative amidophosphoribosyltransferase [Propionibacterium acnes KPA171202]). weak similarity to: pfam00156, Pribosyltran,Phosphoribosyl transferase domain.; Conserved hypothetical protein; putative amidophosphoribosyltransferase 1208151 5175648 CMM_1052 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative amidophosphoribosyltransferase YP_001221793.1 1207348 D 443906 CDS YP_001221794.1 148272233 5175619 1208306..1208995 1 NC_009480.1 putative ribosome-associated protein (YP_061617.1| sigma-54 modulation protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228969.1| COG1544: Ribosome-associated protein Y (PSrp-1) [Kineococcus radiotolerans SRS30216]). pfam02482, Ribosomal_S30AE, Sigma 54 modulation protein / S30EA ribosomal protein.; Function unclear; putative ribosome-associated protein 1208995 5175619 CMM_1053 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ribosome-associated protein YP_001221794.1 1208306 D 443906 CDS YP_001221795.1 148272234 5175626 1209195..1212020 1 NC_009480.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1212020 secA 5175626 secA Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecA YP_001221795.1 1209195 D 443906 CDS YP_001221796.1 148272235 5175541 complement(1212148..1212735) 1 NC_009480.1 hypothetical protein (ZP_00192100.2| hypothetical protein Krad06000007 [Kineococcus radiotolerans SRS30216]; ZP_00294296.1| hypothetical protein Tfus02000501 [Thermobifida fusca]).; hypothetical protein 1212735 5175541 CMM_1055 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221796.1 1212148 R 443906 CDS YP_001221797.1 148272236 5175600 1212939..1213544 1 NC_009480.1 hypothetical protein (ZP_00199350.1| hypothetical protein Krad06000009 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1213544 5175600 CMM_1056 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221797.1 1212939 D 443906 CDS YP_001221798.1 148272237 5175589 1213614..1214252 1 NC_009480.1 hypothetical protein (NP_789084.1| putative membrane/secreted protein [Tropheryma whipplei TW08/27]; ZP_00228975.1| hypothetical protein Krad06000011 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1214252 5175589 CMM_1057 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221798.1 1213614 D 443906 CDS YP_001221799.1 148272238 5175610 1214954..1215841 1 NC_009480.1 Region start changed from 1215161 to 1215047 (114 bases); putative septum formation inhibitor-activating ATPase 1215841 5175610 CMM_1058 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative septum formation inhibitor-activating ATPase YP_001221799.1 1214954 D 443906 CDS YP_001221800.1 148272239 5175584 1215851..1217356 1 NC_009480.1 putative two-component system sensor kinase (ZP_00228292.1| COG3920: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; NP_824193.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system sensor kinase 1217356 5175584 CMM_1059 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001221800.1 1215851 D 443906 CDS YP_001221801.1 148272240 5175591 complement(1217450..1217698) 1 NC_009480.1 putative transcriptional regulator (CAB08318.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB1 [Mycobacterium tuberculosis H37Rv]; NP_696183.1| WhiB-type transcription regulator [Bifidobacterium longum NCC2705]). pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria,required for differentiation and sporulation.; Function unclear; putative transcriptional regulator, WhiB-like 1217698 whiB2 5175591 whiB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator, WhiB-like YP_001221801.1 1217450 R 443906 CDS YP_001221802.1 148272241 5173706 1217945..1218376 1 NC_009480.1 hypothetical membrane protein (YP_062753.1| hypothetical protein Lxx19280 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228293.1| hypothetical protein Krad06001594 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1218376 5173706 CMM_1061 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221802.1 1217945 D 443906 CDS YP_001221803.1 148272242 5175566 complement(1218407..1218886) 1 NC_009480.1 putative alkyl hydroperoxide reductase (bacterioferritin comigratory protein) (NP_961263.1| Bcp [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_826353.1| putative AhpC/TSA family protein [Streptomyces avermitilis MA-4680]). pfam00578, AhpC-TSA,AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Specificity unclear; putative alkyl hydroperoxide reductase 1218886 bcp 5175566 bcp Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alkyl hydroperoxide reductase YP_001221803.1 1218407 R 443906 CDS YP_001221804.1 148272243 5175272 1219388..1219882 1 NC_009480.1 putative transcription factor (ZP_00198110.2| COG1329: Transcriptional regulators, ; NP_301347.1| putative transcription factor [Mycobacterium leprae]). pfam02559, CarD_TRCF, CarD-like/TRCF domain. InterPro: Transcription factor CarD; Function unclear; putative transcription factor 1219882 5175272 CMM_1063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcription factor YP_001221804.1 1219388 D 443906 CDS YP_001221805.1 148272244 5175576 1220007..1220237 1 NC_009480.1 hypothetical protein 1220237 5175576 CMM_1064 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221805.1 1220007 D 443906 CDS YP_001221806.1 148272245 5175559 1220385..1221230 1 NC_009480.1 conserved hypothetical protein (ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]; NP_627325.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1221230 5175559 CMM_1065 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221806.1 1220385 D 443906 CDS YP_001221807.1 148272246 5175556 1221227..1221718 1 NC_009480.1 hypothetical protein 1221718 5175556 CMM_1066 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221807.1 1221227 D 443906 CDS YP_001221808.1 148272247 5175547 complement(1221729..1223261) 1 NC_009480.1 putative L-asparagine permease, APC family (YP_062976.1| L-asparagine permease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226832.1| COG1113: Gamma-aminobutyrate permease and related permeases [Kineococcus radiotolerans SRS30216]). pfam00324, AA_permease, Amino acid permease. InterPro: Amino acid permease; Specificity unclear; L-asparagine permease 1223261 ansP 5175547 ansP Clavibacter michiganensis subsp. michiganensis NCPPB 382 L-asparagine permease YP_001221808.1 1221729 R 443906 CDS YP_001221809.1 148272248 5175913 1223358..1223921 1 NC_009480.1 hypothetical protein 1223921 5175913 CMM_1068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221809.1 1223358 D 443906 CDS YP_001221810.1 148272249 5175532 complement(1223970..1225298) 1 NC_009480.1 putative MFS permease (YP_061411.1| integral membrane efflux protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00283009.1| COG0477: Permeases of the major facilitator superfamily [Burkholderia fungorum LB400]). TIGRFAM( TIGR00900): H+ Antiporter protein; Specificity unclear; putative MFS permease 1225298 5175532 CMM_1069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221810.1 1223970 R 443906 CDS YP_001221811.1 148272250 5175498 complement(1225295..1225717) 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_959753.1| hypothetical protein MAP0819 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_825072.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 1225717 5175498 CMM_1070 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001221811.1 1225295 R 443906 CDS YP_001221812.1 148272251 5175507 1225905..1226081 1 NC_009480.1 hypothetical protein 1226081 5175507 CMM_1071 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221812.1 1225905 D 443906 CDS YP_001221813.1 148272252 5175479 1226186..1227004 1 NC_009480.1 putative hydrolase/acyltransferase (NP_532260.1| hydrolase [Agrobacterium tumefaciens str. C58]; NP_981307.1| hydrolase, alpha/beta fold family [Bacillus cereus ATCC 10987]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. acid_CoA_mut_C: methylmalonyl-CoA muta; Function unclear; putative hydrolase/acyltransferase 1227004 5175479 CMM_1072 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001221813.1 1226186 D 443906 CDS YP_001221814.1 148272253 5175492 complement(1227054..1228922) 1 NC_009480.1 putative glycosyl hydrolase, family 15 (YP_062268.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292808.1| COG3387: Glucoamylase and related glycosyl hydrolases [Thermobifida fusca]). pfam00723, Glyco_hydro_15, Glycosyl hydrolases family 15.; Function unclear; glycoside hydrolase family protein 1228922 5175492 CMM_1073 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycoside hydrolase family protein YP_001221814.1 1227054 R 443906 CDS YP_001221815.1 148272254 5175454 1228980..1230362 1 NC_009480.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1230362 zwfB 5175454 zwfB Clavibacter michiganensis subsp. michiganensis NCPPB 382 glucose-6-phosphate 1-dehydrogenase YP_001221815.1 1228980 D 443906 CDS YP_001221816.1 148272255 5174396 complement(1230394..1231041) 1 NC_009480.1 hypothetical protein 1231041 5174396 CMM_1075 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221816.1 1230394 R 443906 CDS YP_001221817.1 148272256 5175485 1231254..1232483 1 NC_009480.1 putative small-conductance mechanosensitive channel (ZP_00227048.1| COG0668: Small-conductance mechanosensitive channel [Kineococcus radiotolerans SRS30216]; ZP_00023357.1| COG0668: Small-conductance mechanosensitive channel [Ralstonia metallidurans]). pfam00924, MS_channel, Mechanosensitive ion channel.; Function unclear; putative small-conductance mechanosensitive channel 1232483 5175485 CMM_1076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative small-conductance mechanosensitive channel YP_001221817.1 1231254 D 443906 CDS YP_001221818.1 148272257 5175442 1232898..1234052 1 NC_009480.1 putative arsenate permease, ArsB family (Arsenic efflux pump protein)(YP_062266.1| arsenical pump membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_736635.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00226785.1| COG1055: Na+/H+ antiporter NhaD and related arsenite permeases [Kineococcus radiotolerans SRS30216]). Involved in arsenical resistance. Thought to form the channel of an arsenite pump. 2a45: arsenical pump membrane protein pfam02040, ArsB, Arsenical pump membrane protein.; Specificity unclear; ArsB family arsenate permease 1234052 arsB 5175442 arsB Clavibacter michiganensis subsp. michiganensis NCPPB 382 ArsB family arsenate permease YP_001221818.1 1232898 D 443906 CDS YP_001221819.1 148272258 5173216 1234135..1234713 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_959728.1| hypothetical protein MAP0794 [Mycobacterium avium subsp. paratuberculosis str. k10]; AAD13556.1| LanK [Streptomyces cyanogenus]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1234713 5173216 CMM_1078 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221819.1 1234135 D 443906 CDS YP_001221820.1 148272259 5175471 1234760..1237708 1 NC_009480.1 putative drug exporter, RND family (YP_054789.1| putative membrane transport protein [Propionibacterium acnes KPA171202]; NP_824795.1| putative drug exporters of the RND superfamily [Streptomyces avermitilis MA-4680]). actII: Transport protein; Specificity unclear; RND superfamily drug exporter 1237708 5175471 CMM_1079 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RND superfamily drug exporter YP_001221820.1 1234760 D 443906 CDS YP_001221821.1 148272260 5175239 1237705..1239600 1 NC_009480.1 conserved membrane protein (NP_961301.1| hypothetical protein MAP2367c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_827281.1| putative membrane protein [Streptomyces avermitilis MA-4680]). Mtu_efflux: ABC transporter efflux pro; Function unclear; hypothetical protein 1239600 5175239 CMM_1080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221821.1 1237705 D 443906 CDS YP_001221822.1 148272261 5175432 1239603..1241030 1 NC_009480.1 hypothetical protein 1241030 5175432 CMM_1081 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221822.1 1239603 D 443906 CDS YP_001221823.1 148272262 5175102 complement(1241105..1241407) 1 NC_009480.1 conserved hypothetical protein, putative monooxygenase (ZP_00226413.1| COG1359: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_959730.1| hypothetical protein MAP0796c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase.; putative monooxygenase 1241407 5175102 CMM_1082 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001221823.1 1241105 R 443906 CDS YP_001221824.1 148272263 5175806 complement(1241582..1242457) 1 NC_009480.1 putative sugar phosphate isomerase/epimerase (NP_627556.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00057048.1| COG1082: Sugar phosphate isomerases/epimerases [Thermobifida fusca]). pfam01261, AP_endonuc_2, AP endonuclease family 2.; Specificity unclear; hypothetical protein 1242457 5175806 CMM_1083 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221824.1 1241582 R 443906 CDS YP_001221825.1 148272264 5174790 1242606..1243430 1 NC_009480.1 conserved hypothetical protein, putative sugar kinase (NP_601735.1| hypothetical protein [Corynebacterium glutamicum ATCC 13032]; ZP_00225866.1| COG3001: Fructosamine-3-kinase [Kineococcus radiotolerans SRS30216]). pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterised but probably have a similar or identical function.; putative sugar kinase 1243430 5174790 CMM_1084 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar kinase YP_001221825.1 1242606 D 443906 CDS YP_001221826.1 148272265 5175256 1243531..1245126 1 NC_009480.1 putative trehalose-phosphate synthase (UDP-glucose-glucosephosphate glucosyltransferase) (YP_062264.1| trehalose-6-phosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225984.1| COG0380: Trehalose-6-phosphate synthase [Kineococcus radiotolerans SRS30216]). pfam00982, Glyco_transf_20, Glycosyltransferase family 20.; High confidence in function and specificity; putative trehalose-phosphate synthase 1245126 otsA 5175256 otsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative trehalose-phosphate synthase YP_001221826.1 1243531 D 443906 CDS YP_001221827.1 148272266 5175662 1245132..1245959 1 NC_009480.1 putative trehalose-phosphatase (Trehalose 6-phosphate phosphatase) (ZP_00225983.1| COG1877: Trehalose-6-phosphatase [Kineococcus radiotolerans SRS30216]; NP_940299.1| Putative trehalose-phosphatase [Corynebacterium diphtheriae]). pfam02358,Trehalose_PPase, Trehalose-phosphatase. otsB: trehalose-phosphatase.; High confidence in function and specificity; putative trehalose-phosphatase 1245959 otsB 5175662 otsB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative trehalose-phosphatase YP_001221827.1 1245132 D 443906 CDS YP_001221828.1 148272267 5175252 1246033..1249041 1 NC_009480.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit A 1249041 mnhAB 5175252 mnhAB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monovalent cation/H+ antiporter subunit A YP_001221828.1 1246033 D 443906 CDS YP_001221829.1 148272268 5175605 1249038..1249598 1 NC_009480.1 putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00226457.1| COG1006: Multisubunit Na+/H+ antiporter, MnhC subunit [Kineococcus radiotolerans SRS30216]; NP_739178.1| putative Na+/H+ antiporter [Corynebacterium efficiens YS-314]). pfam00420,Oxidored_q2, NADH-ubiquinone/plastoquinone oxidoreductase chain 4L. TIGRFAM (TIGR00941): Multicomponent Na+:H+ antiporter.; High confidence in function and specificity; putative Na+/H+ antiporter subunit 1249598 mnhC 5175605 mnhC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Na+/H+ antiporter subunit YP_001221829.1 1249038 D 443906 CDS YP_001221830.1 148272269 5172993 1249595..1251187 1 NC_009480.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; putative monovalent cation/H+ antiporter subunit D 1251187 mnhD 5172993 mnhD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monovalent cation/H+ antiporter subunit D YP_001221830.1 1249595 D 443906 CDS YP_001221831.1 148272270 5173988 1251184..1251858 1 NC_009480.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit E 1251858 mnhE 5173988 mnhE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monovalent cation/H+ antiporter subunit E YP_001221831.1 1251184 D 443906 CDS YP_001221832.1 148272271 5175439 1251855..1252130 1 NC_009480.1 putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00292641.1| hypothetical protein Tfus02001919 [Thermobifida fusca]; AAR35714.1| monovalent cation/proton antiporter, MrpF/PhaF family [Geobacter sulfurreducens PCA]).; High confidence in function and specificity; putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase 1252130 mnhF 5175439 mnhF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase YP_001221832.1 1251855 D 443906 CDS YP_001221833.1 148272272 5173653 1252127..1252699 1 NC_009480.1 putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase (ZP_00292640.1| COG1320: Multisubunit Na+/H+ antiporter, MnhG subunit [Thermobifida fusca]; ZP_00198672.2| COG1320: Multisubunit Na+/H+ antiporter, MnhG subunit [Kineococcus radiotolerans SRS30216]). pfam03334, PhaG_MnhG_YufB, Na+/H+ antiporter subunit.; Family membership; putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase 1252699 mnhG 5173653 mnhG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multisubunit Na+/H+ antiporter, NADH-quinone dehydrogenase YP_001221833.1 1252127 D 443906 CDS YP_001221834.1 148272273 5174345 1252765..1254459 1 NC_009480.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1254459 ilvD 5174345 ilvD Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydroxy-acid dehydratase YP_001221834.1 1252765 D 443906 CDS YP_001221835.1 148272274 5174479 1254456..1256339 1 NC_009480.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase 1 catalytic subunit 1256339 ilvB 5174479 ilvB Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetolactate synthase 1 catalytic subunit YP_001221835.1 1254456 D 443906 CDS YP_001221836.1 148272275 5174379 1256336..1256845 1 NC_009480.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1256845 ilvH 5174379 ilvH Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetolactate synthase 3 regulatory subunit YP_001221836.1 1256336 D 443906 CDS YP_001221837.1 148272276 5173472 1257014..1258039 1 NC_009480.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1258039 ilvC 5173472 ilvC Clavibacter michiganensis subsp. michiganensis NCPPB 382 ketol-acid reductoisomerase YP_001221837.1 1257014 D 443906 CDS YP_001221838.1 148272277 5174982 1258173..1258706 1 NC_009480.1 Hypothetical protein; hypothetical protein 1258706 5174982 CMM_1097 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221838.1 1258173 D 443906 CDS YP_001221839.1 148272278 5175090 1258703..1259071 1 NC_009480.1 Hypothetical protein; hypothetical protein 1259071 5175090 CMM_1098 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221839.1 1258703 D 443906 CDS YP_001221840.1 148272279 5175933 complement(1259081..1259482) 1 NC_009480.1 conserved membrane protein (NP_869710.1| conserved hypothetical protein-putative transmembrane protein [Pirellula sp. 1]; ZP_00110025.1| COG4270: Predicted membrane protein [Nostoc punctiforme]).; hypothetical protein 1259482 5175933 CMM_1099 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221840.1 1259081 R 443906 CDS YP_001221841.1 148272280 5175949 1259548..1261137 1 NC_009480.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1261137 serA 5175949 serA Clavibacter michiganensis subsp. michiganensis NCPPB 382 D-3-phosphoglycerate dehydrogenase YP_001221841.1 1259548 D 443906 CDS YP_001221842.1 148272281 5175137 complement(1261216..1261839) 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00198420.1| hypothetical protein Krad024089 [Kineococcus radiotolerans SRS30216]; NP_691916.1| transcriptional regulator [Oceanobacillus iheyensis HTE831]). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator 1261839 5175137 CMM_1101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221842.1 1261216 R 443906 CDS YP_001221843.1 148272282 5173740 1261961..1263502 1 NC_009480.1 putative efflux MFS permease (CAE15934.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]; AAN50737.1| possible transmembrane-transport protein [Leptospira interrogans serovar lai str. 56601]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative efflux MFS permease 1263502 5173740 CMM_1102 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative efflux MFS permease YP_001221843.1 1261961 D 443906 CDS YP_001221844.1 148272283 5174130 complement(1263580..1263834) 1 NC_009480.1 hypothetical membrane protein (NP_627991.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00225753.1| hypothetical protein Krad06004516 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1263834 5174130 CMM_1103 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221844.1 1263580 R 443906 CDS YP_001221845.1 148272284 5175261 1263947..1265014 1 NC_009480.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1265014 leuB 5175261 leuB Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-isopropylmalate dehydrogenase YP_001221845.1 1263947 D 443906 CDS YP_001221846.1 148272285 5174161 1265023..1266153 1 NC_009480.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 1266153 ilvE 5174161 ilvE Clavibacter michiganensis subsp. michiganensis NCPPB 382 branched-chain amino acid aminotransferase YP_001221846.1 1265023 D 443906 CDS YP_001221847.1 148272286 5173337 1266211..1266984 1 NC_009480.1 putative 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase, putative fumarylacetoacetate (FAA) hydrolase (YP_062251.1| 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293380.1| COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Thermobifida fusca]). pfam01557,FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.; Function unclear; hypothetical protein 1266984 5173337 CMM_1106 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221847.1 1266211 D 443906 CDS YP_001221848.1 148272287 5174336 1266987..1267745 1 NC_009480.1 hypothetical protein 1267745 5174336 CMM_1107 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221848.1 1266987 D 443906 CDS YP_001221849.1 148272288 5175327 1267759..1269279 1 NC_009480.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1269279 gltX 5175327 gltX Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamyl-tRNA synthetase YP_001221849.1 1267759 D 443906 CDS YP_001221850.1 148272289 5174201 1269272..1270222 1 NC_009480.1 putative thioredoxin reductase (YP_062249.1| pyridine nucleotide- disulfide oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_028840.1| thioredoxin reductase, putative [Bacillus anthracis str. Sterne]). ,pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Function unclear; putative thioredoxin reductase 1270222 trxB2 5174201 trxB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin reductase YP_001221850.1 1269272 D 443906 CDS YP_001221851.1 148272290 5174660 1270661..1274278 1 NC_009480.1 conserved hypothetical protein (AAB84461.1| DNA-binding protein [Bacillus subtilis]; AAO79850.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]).; hypothetical protein 1274278 5174660 CMM_1110 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221851.1 1270661 D 443906 CDS YP_001221852.1 148272291 5174410 1274459..1274689 1 NC_009480.1 hypothetical protein (NP_737865.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 1274689 5174410 CMM_1111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221852.1 1274459 D 443906 CDS YP_001221853.1 148272292 5174274 complement(1274834..1275844) 1 NC_009480.1 putative K+ channel protein, beta subunit (ZP_00228108.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAD19081.1| potassium channel beta chain [Stigmatella aurantiaca]). Pfam: Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity. Voltage-gated potassium channel beta-1 subunit (K+ channel beta-1 subunit) (Kv-beta-1). ACCESSORY POTASSIUM CHANNEL PROTEIN WHICH MODULATES THE ACTIVITY OF THE PORE-FORMING ALPHA SUBUNIT (BY SIMILARITY). InterPro: Aldo/keto reductase family; Function unclear; putative K+ channel protein, beta subunit 1275844 5174274 CMM_1112 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative K+ channel protein, beta subunit YP_001221853.1 1274834 R 443906 CDS YP_001221854.1 148272293 5174535 complement(1275979..1276989) 1 NC_009480.1 putative potassium channel protein subunit (ZP_00228108.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAD19081.1| potassium channel beta chain [Stigmatella aurantiaca]). pfam00248,Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative potassium channel protein subunit 1276989 5174535 CMM_1113 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative potassium channel protein subunit YP_001221854.1 1275979 R 443906 CDS YP_001221855.1 148272294 5173865 complement(1277057..1277671) 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_624827.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; NP_959089.1| hypothetical protein MAP0155 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator 1277671 5173865 CMM_1114 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221855.1 1277057 R 443906 CDS YP_001221856.1 148272295 5173793 1277727..1278524 1 NC_009480.1 putative short-chain dehydrogenase (ZP_00229050.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; CAB58271.1| putative dehydrogenase (putative secreted protein) [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Function unclear; putative short chain dehydrogenase 1278524 5173793 CMM_1115 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase YP_001221856.1 1277727 D 443906 CDS YP_001221857.1 148272296 5174894 complement(1278593..1279696) 1 NC_009480.1 conserved membrane protein, TerC family (NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]; YP_061942.1| membrane protein, tellurium resistance [Leifsonia xyli subsp. xyli str. CTCB07]). pfam03741, TerC, Integral membrane protein TerC family. This family contains a number of integral membrane proteins that also contains the TerC protein. TerC has been implicated in resistance to tellurium. This protein may be involved in efflux of tellurium ions.; Function unclear; TerC family membrane protein 1279696 5174894 CMM_1116 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TerC family membrane protein YP_001221857.1 1278593 R 443906 CDS YP_001221858.1 148272297 5175592 complement(1279936..1280352) 1 NC_009480.1 Hypothetical protein; hypothetical protein 1280352 5175592 CMM_1117 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221858.1 1279936 R 443906 CDS YP_001221859.1 148272298 5174901 complement(1280395..1281033) 1 NC_009480.1 putative Zn-dependant hydrolase (NP_335238.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_630432.1| conserved hypothetical protein SC3A7.08 [Streptomyces coelicolor A3(2)]). pfam00753,Lactamase_B, Metallo-beta-lactamase superfamily. menD: 2-succinyl-6-hydroxy-24-cyclohex; Function unclear; putative Zn-dependant hydrolase 1281033 5174901 CMM_1118 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant hydrolase YP_001221859.1 1280395 R 443906 CDS YP_001221860.1 148272299 5175652 1281390..1282106 1 NC_009480.1 putative serine protease, family S51 , related to cyanophycinase (NP_824488.1| hypothetical protein [Streptomyces avermitilis MA-4680]; YP_056776.1| hypothetical protein PPA2111 [Propionibacterium acnes KPA171202]). pfam03575, Peptidase_S51, Peptidase family S51.; Function unclear; S51 family peptidase 1282106 5175652 CMM_1119 Clavibacter michiganensis subsp. michiganensis NCPPB 382 S51 family peptidase YP_001221860.1 1281390 D 443906 CDS YP_001221861.1 148272300 5175346 1282117..1282803 1 NC_009480.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1282803 ungA 5175346 ungA Clavibacter michiganensis subsp. michiganensis NCPPB 382 uracil-DNA glycosylase YP_001221861.1 1282117 D 443906 CDS YP_001221862.1 148272301 5173297 1282857..1283546 1 NC_009480.1 putative acetyltransferase (YP_062723.1| phosphinothricin acetyltransferase protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00054060.1| COG1247: Sortase and related acyltransferases [Magnetospirillum magnetotacticum]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1283546 5173297 CMM_1121 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221862.1 1282857 D 443906 CDS YP_001221863.1 148272302 5174755 complement(1283428..1284360) 1 NC_009480.1 Region start changed from 1284588 to 1284360 (-228 bases); putative membrane bound protease 1284360 5174755 CMM_1122 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane bound protease YP_001221863.1 1283428 R 443906 CDS YP_001221864.1 148272303 5175804 complement(1286708..1287331) 1 NC_009480.1 putative hexulose-6-phosphate synthase (D-arabino 3-hexulose 6-phosphate formaldehyde lyase) (CAD28138.1| putative 3-hexulose-6-phosphate synthase [Rhodococcus opacus]; BAA90546.1| 3-hexulose-6-phosphate synthase [Mycobacterium gastri]). pfam00215, OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family.; High confidence in function and specificity; putative hexulose-6-phosphate synthase 1287331 sgaH 5175804 sgaH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hexulose-6-phosphate synthase YP_001221864.1 1286708 R 443906 CDS YP_001221865.1 148272304 5175046 complement(1287384..1287992) 1 NC_009480.1 putative 6-phospho-3-hexuloisomerase (BAA90545.1| 6-phospho- 3-hexuloisomerase [Mycobacterium gastri]; CAD28139.1| putative 6-phospho-3-hexuloisomerase [Rhodococcus opacus]). pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.; Function unclear; putative 6-phospho-3-hexuloisomerase 1287992 5175046 CMM_1124 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 6-phospho-3-hexuloisomerase YP_001221865.1 1287384 R 443906 CDS YP_001221866.1 148272305 5175269 1288259..1289437 1 NC_009480.1 putative transcriptional regulator, LuxR family (CAD28140.1| putative LuxR-like transcriptional regulator [Rhodococcus opacus]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. pfam00196,GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; LuxR family transcriptional regulator 1289437 5175269 CMM_1125 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LuxR family transcriptional regulator YP_001221866.1 1288259 D 443906 CDS YP_001221867.1 148272306 5175718 1289562..1291709 1 NC_009480.1 putative 5'-nucleotidase (YP_056763.1| 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Propionibacterium acnes KPA171202]; NP_736947.1| 5'-nucleotidase [Corynebacterium efficiens YS-314]). pfam00149, Metallophos, Calcineurin-like phosphoesterase. pfam02872, 5_nucleotid_C, 5'-nucleotidase, C-terminal domain. InterPro: 5-Nucleotidase; Function unclear; putative 5'-nucleotidase 1291709 5175718 CMM_1126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 5'-nucleotidase YP_001221867.1 1289562 D 443906 CDS YP_001221868.1 148272307 5175799 1291820..1293247 1 NC_009480.1 putative Asp/Glu-tRNA amidotransferase (ZP_00058755.1| COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Thermobifida fusca]; ZP_00111119.1| COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Nostoc punctiforme]). pfam01425, Amidase,Amidase.; Specificity unclear; putative Asp/Glu-tRNA amidotransferase 1293247 5175799 CMM_1127 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Asp/Glu-tRNA amidotransferase YP_001221868.1 1291820 D 443906 CDS YP_001221869.1 148272308 5173844 complement(1293257..1293994) 1 NC_009480.1 conserved membrane protein (NP_738052.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; NP_631844.1| putative membrane protein. [Streptomyces coelicolor A3(2)]). pfam01925, DUF81, Domain of unknown function DUF81. This integral membrane protein family has no known function.; Function unclear; hypothetical protein 1293994 5173844 CMM_1128 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221869.1 1293257 R 443906 CDS YP_001221870.1 148272309 5175773 1294075..1295067 1 NC_009480.1 putative siderophore-interacting protein (ZP_00227633.1| COG2375: Siderophore-interacting protein [Kineococcus radiotolerans SRS30216]; NP_737293.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). involved in the intracellular removol of iron from siderophores. pfam04954, SIP, Siderophore-interacting protein.; Specificity unclear; putative siderophore-interacting protein 1295067 5175773 CMM_1129 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative siderophore-interacting protein YP_001221870.1 1294075 D 443906 CDS YP_001221871.1 148272310 5174599 complement(1295500..1296378) 1 NC_009480.1 putative short-chain alcohol dehydrogenase (ZP_00227858.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; YP_061632.1| oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain alcohol dehydrogenase 1296378 5174599 CMM_1130 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain alcohol dehydrogenase YP_001221871.1 1295500 R 443906 CDS YP_001221872.1 148272311 5175695 complement(1296375..1296767) 1 NC_009480.1 hypothetical protein (ZP_00299320.1| hypothetical protein Gmet02002474 [Geobacter metallireducens GS-15]; ZP_00189534.3| hypothetical protein Krad06003867 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1296767 5175695 CMM_1131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221872.1 1296375 R 443906 CDS YP_001221873.1 148272312 5175802 complement(1296764..1298197) 1 NC_009480.1 putative pyridine nucleotide-disulphide oxidoreductase (CAA73871.1| mercuric reductase/glutathione reductase/ dihydrolipoamide dehydrogenase [Mycobacterium tuberculosis]; NP_821842.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]). pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. pfam02852,Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.; Function unclear; putative pyridine nucleotide-disulphide oxidoreductase 1298197 5175802 CMM_1132 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyridine nucleotide-disulphide oxidoreductase YP_001221873.1 1296764 R 443906 CDS YP_001221874.1 148272313 5175058 complement(1298254..1299093) 1 NC_009480.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1299093 echA 5175058 echA Clavibacter michiganensis subsp. michiganensis NCPPB 382 enoyl-CoA hydratase YP_001221874.1 1298254 R 443906 CDS YP_001221875.1 148272314 5175514 complement(1299162..1300004) 1 NC_009480.1 putative arginase (YP_061703.1| arginase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291576.1| COG0010: Arginase/agmatinase/ formimionoglutamate hydrolase,arginase family [Thermobifida fusca]). pfam00491,Arginase, Arginase family.; Specificity unclear; hypothetical protein 1300004 5175514 CMM_1134 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221875.1 1299162 R 443906 CDS YP_001221876.1 148272315 5174496 complement(1300110..1300760) 1 NC_009480.1 putative F420-dependent NADP reductase (ZP_00228826.1| COG2085: Predicted dinucleotide-binding enzymes [Kineococcus radiotolerans SRS30216]; AAR32680.1| conserved hypothetical protein [Streptomyces hygroscopicus]). pfam03807, F420_oxidored, NADP oxidoreductase coenzyme F420-dependent.; Function unclear; putative F420-dependent NADP reductase 1300760 5174496 CMM_1135 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative F420-dependent NADP reductase YP_001221876.1 1300110 R 443906 CDS YP_001221877.1 148272316 5175088 complement(1300855..1301598) 1 NC_009480.1 conserved hypothetical protein, ; ZP_00326969.1| COG1842: Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Trichodesmium erythraeum IMS101]). pfam04012, PspA_IM30, PspA/IM30 family.; Function unclear; hypothetical protein 1301598 5175088 CMM_1136 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221877.1 1300855 R 443906 CDS YP_001221878.1 148272317 5174578 complement(1301683..1303725) 1 NC_009480.1 conserved hypothetical protein (NP_336889.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; ZP_00227832.1| COG1512: Beta-propeller domains of methanol dehydrogenase type [Kineococcus radiotolerans SRS30216]). pfam04536, DUF477, Domain of unknown function (DUF477). The function of this presumed domain is unknown. EIIA-LAC: PTS system lactose-specifi; hypothetical protein 1303725 5174578 CMM_1137 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221878.1 1301683 R 443906 CDS YP_001221879.1 148272318 5175430 complement(1303814..1304239) 1 NC_009480.1 hypothetical protein (NP_336075.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]).; hypothetical protein 1304239 5175430 CMM_1138 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221879.1 1303814 R 443906 CDS YP_001221880.1 148272319 5174505 complement(1304368..1304679) 1 NC_009480.1 hypothetical protein 1304679 5174505 CMM_1139 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221880.1 1304368 R 443906 CDS YP_001221881.1 148272320 5173323 1305414..1306103 1 NC_009480.1 putative pyridoxamine-phosphate oxidase (NP_628586.1| putative oxidase [Streptomyces coelicolor A3(2)]; ZP_00013664.1| COG0259: Pyridoxamine-phosphate oxidase [Rhodospirillum rubrum]). pfam01243,Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase.; Specificity unclear; putative pyridoxamine-phosphate oxidase 1306103 5173323 CMM_1140 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyridoxamine-phosphate oxidase YP_001221881.1 1305414 D 443906 CDS YP_001221882.1 148272321 5174364 1306214..1306984 1 NC_009480.1 putative glutamine amidotransferase (ZP_00331246.1| COG2071: Predicted glutamine amidotransferases [Moorella thermoacetica ATCC 39073]; NP_302088.1| possible amidotransferase [Mycobacterium leprae TN]). pfam00117,GATase, Glutamine amidotransferase class-I. InterPro: Glutamine amidotransferase class-I; Function unclear; putative glutamine amidotransferase 1306984 5174364 CMM_1141 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamine amidotransferase YP_001221882.1 1306214 D 443906 CDS YP_001221883.1 148272322 5174843 complement(1307034..1307789) 1 NC_009480.1 putative short chain alcohol dehydrogenase (AAO42633.1| putative short-chain dehydrogenase [Ralstonia eutropha]; AAO57656.1| oxidoreductase, short chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000] pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain alcohol dehydrogenase 1307789 5174843 CMM_1142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain alcohol dehydrogenase YP_001221883.1 1307034 R 443906 CDS YP_001221884.1 148272323 5174580 complement(1307786..1308553) 1 NC_009480.1 putative short chain alcohol dehydrogenase (AAO57657.1| oxidoreductase, short chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; ZP_00126580.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Pseudomonas syringae pv. syringae B728a]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; High confidence in function and specificity; putative short chain alcohol dehydrogenase 1308553 5174580 CMM_1143 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain alcohol dehydrogenase YP_001221884.1 1307786 R 443906 CDS YP_001221885.1 148272324 5173861 complement(1308550..1309935) 1 NC_009480.1 putative MFS permease (ZP_00126581.1| COG0477: Permeases of the major facilitator superfamily [Pseudomonas syringae pv. syringae B728a]; NP_992822.1| putative sugar transporter [Yersinia pestis biovar Medievalis str. 91001]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 1309935 5173861 CMM_1144 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001221885.1 1308550 R 443906 CDS YP_001221886.1 148272325 5174633 complement(1309970..1310860) 1 NC_009480.1 putative deacetylase (ZP_00126582.1| COG0726: Predicted xylanase/chitin deacetylase [Pseudomonas syringae pv. syringae B728a]; NP_738966.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01522, Polysacc_deac_1, Polysaccharide deacetylase. This domain is found in polysaccharide deacetylase. This family of polysaccharide deacetylases includes NodB (nodulation protein B from Rhizobium) which is a chitooligosaccharide deacetylase. It also includes chitin deacetylase from yeast, and endoxylanases which hydrolyses glucosidic bonds in xylan.; Specificity unclear; putative deacetylase 1310860 5174633 CMM_1145 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative deacetylase YP_001221886.1 1309970 R 443906 CDS YP_001221887.1 148272326 5174734 complement(1310886..1311911) 1 NC_009480.1 Region start changed from 1311968 to 1311911 (-57 bases); putative asparaginase 1311911 5174734 CMM_1146 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative asparaginase YP_001221887.1 1310886 R 443906 CDS YP_001221888.1 148272327 5174650 1312083..1313111 1 NC_009480.1 putative transcriptional regulator, LacI family (NP_886234.1| LacI family transcriptional regulator [Bordetella parapertussis 12822]; NP_535765.1| transcriptional regulator, LacI family [Agrobacterium tumefaciens str. C58]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 1313111 5174650 CMM_1147 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001221888.1 1312083 D 443906 CDS YP_001221889.1 148272328 5173558 1313187..1313981 1 NC_009480.1 conserved hypothetical protein (NP_865622.1| conserved hypothetical protein [Pirellula sp. 1]; ZP_00117918.1| COG1305: Transglutaminase-like enzymes,putative cysteine proteases [Cytophaga hutchinsonii]). pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Family membership; hypothetical protein 1313981 5173558 CMM_1148 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221889.1 1313187 D 443906 CDS YP_001221890.1 148272329 5174653 complement(1314009..1314656) 1 NC_009480.1 hypothetical protein TIGR00426: competence protein ComEA helix; hypothetical protein 1314656 5174653 CMM_1149 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221890.1 1314009 R 443906 CDS YP_001221891.1 148272330 5175073 1314856..1316520 1 NC_009480.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1316520 argS 5175073 argS Clavibacter michiganensis subsp. michiganensis NCPPB 382 arginyl-tRNA synthetase YP_001221891.1 1314856 D 443906 CDS YP_001221892.1 148272331 5173694 1316632..1317363 1 NC_009480.1 hypothetical protein (YP_061720.1| hypothetical protein Lxx06820 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825215.1| hypothetical protein SAV4038 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1317363 5173694 CMM_1151 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221892.1 1316632 D 443906 CDS YP_001221893.1 148272332 5175251 1317520..1319019 1 NC_009480.1 Diaminopimelate decarboxylase (DAP decarboxylase)(YP_061724.1| diaminopimelate decarboxylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228463.1| COG0019: Diaminopimelate decarboxylase [Kineococcus radiotolerans SRS30216]). pfam02784, Orn_Arg_deC_N,Pyridoxal-dependent decarboxylase, pyridoxal binding domain. pfam00278, Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain.; High confidence in function and specificity; hypothetical protein 1319019 lysA 5175251 lysA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221893.1 1317520 D 443906 CDS YP_001221894.1 148272333 5174594 1319016..1320347 1 NC_009480.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1320347 thrA 5174594 thrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 homoserine dehydrogenase YP_001221894.1 1319016 D 443906 CDS YP_001221895.1 148272334 5174679 1320347..1321423 1 NC_009480.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1321423 thrC 5174679 thrC Clavibacter michiganensis subsp. michiganensis NCPPB 382 threonine synthase YP_001221895.1 1320347 D 443906 CDS YP_001221896.1 148272335 5174857 1321435..1322385 1 NC_009480.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1322385 thrB 5174857 thrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 homoserine kinase YP_001221896.1 1321435 D 443906 CDS YP_001221897.1 148272336 5173268 1322682..1325153 1 NC_009480.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1325153 5173268 CMM_1156 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcription termination factor Rho YP_001221897.1 1322682 D 443906 CDS YP_001221898.1 148272337 5174167 1325159..1326238 1 NC_009480.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1326238 prfA 5174167 prfA Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptide chain release factor 1 YP_001221898.1 1325159 D 443906 CDS YP_001221899.1 148272338 5173923 1326263..1327138 1 NC_009480.1 putative methylase of peptide chain release factors (YP_061731.1| methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824087.1| putative methyltransferase [Streptomyces avermitilis MA-4680]). TIGRFam: hemK_fam: modification methylase HemK; Function unclear; putative methylase of peptide chain release factors 1327138 5173923 CMM_1158 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylase of peptide chain release factors YP_001221899.1 1326263 D 443906 CDS YP_001221900.1 148272339 5175221 complement(1327166..1327819) 1 NC_009480.1 putative hydrolase/phosphatase (ZP_00167336.1| COG1011: Predicted hydrolase (HAD superfamily) [Ralstonia eutropha JMP134]; NP_671096.1| putative phosphatase [Yersinia pestis KIM]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Family membership; hypothetical protein 1327819 5175221 CMM_1159 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221900.1 1327166 R 443906 CDS YP_001221901.1 148272340 5175901 1327903..1328832 1 NC_009480.1 conserved hypothetical protein (ZP_00228471.1| COG0009: Putative translation factor (SUA5) [Kineococcus radiotolerans SRS30216]; NP_824086.1| hypothetical protein SAV2910 [Streptomyces avermitilis MA-4680]). pfam01300, Sua5_yciO_yrdC, yrdC domain. This domain has been shown to preferentially bind to dsRNA. The domain is found in SUA5 as well as HypF and YrdC.; hypothetical protein 1328832 5175901 CMM_1160 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221901.1 1327903 D 443906 CDS YP_001221902.1 148272341 5174450 1328829..1330148 1 NC_009480.1 putative undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (YP_061734.1| undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824083.1| putative teichoic acid linkage unit synthesis (synthesis of undecaprenylpyrophosphate-N-aetylglucosamine), Streptomyces avermitilis MA-4680). pfam00953, Glycos_transf_4, Glycosyl transferase InterPro: Glycosyl transferase family 4; Function unclear; putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 1330148 rfeA 5174450 rfeA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_001221902.1 1328829 D 443906 CDS YP_001221903.1 148272342 5174353 1330145..1330615 1 NC_009480.1 conserved membrane protein (YP_061735.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737918.1| hypothetical protein [Corynebacterium efficiens YS-314]). eventually involved in ATP synthesis (weak similarity to AtpI); Function unclear; hypothetical protein 1330615 5174353 CMM_1162 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221903.1 1330145 D 443906 CDS YP_001221904.1 148272343 5175770 1330770..1331618 1 NC_009480.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1331618 atpB 5175770 atpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit A YP_001221904.1 1330770 D 443906 CDS YP_001221905.1 148272344 5174416 1331665..1331898 1 NC_009480.1 ATP synthase C chain (Lipid-binding protein) (YP_061737.1| ATP synthase, C chain [Leifsonia xyli subsp. xyli str. CTCB07]; AAS68133.1| ATP synthase C subunit [Bifidobacterium animalis]). THIS IS ONE OF THE THREE CHAINS OF THE NONENZYMATIC COMPONENT (CF(0) SUBUNIT) OF THE ATPASE COMPLEX. pfam00137, ATP-synt_C, ATP synthase subunit C.; High confidence in function and specificity; ATP synthase C chain (Lipid-binding protein) 1331898 atpE 5174416 atpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP synthase C chain (Lipid-binding protein) YP_001221905.1 1331665 D 443906 CDS YP_001221906.1 148272345 5174260 1331910..1332476 1 NC_009480.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1332476 atpF 5174260 atpF Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit B YP_001221906.1 1331910 D 443906 CDS YP_001221907.1 148272346 5175816 1332476..1333267 1 NC_009480.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1333267 atpH 5175816 atpH Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit delta YP_001221907.1 1332476 D 443906 CDS YP_001221908.1 148272347 5173925 1333323..1334960 1 NC_009480.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1334960 atpA 5173925 atpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit alpha YP_001221908.1 1333323 D 443906 CDS YP_001221909.1 148272348 5174489 1335010..1335909 1 NC_009480.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1335909 atpG 5174489 atpG Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit gamma YP_001221909.1 1335010 D 443906 CDS YP_001221910.1 148272349 5173321 1335945..1337405 1 NC_009480.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1337405 atpD 5173321 atpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit beta YP_001221910.1 1335945 D 443906 CDS YP_001221911.1 148272350 5174537 1337407..1337676 1 NC_009480.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 1337676 atpC 5174537 atpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 F0F1 ATP synthase subunit epsilon YP_001221911.1 1337407 D 443906 CDS YP_001221912.1 148272351 5174397 1337796..1338551 1 NC_009480.1 conserved hypothetical protein (YP_061745.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738499.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03883, DUF328,Protein of unknown function (DUF328). Members of this family are functionally uncharacterised.; hypothetical protein 1338551 5174397 CMM_1171 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221912.1 1337796 D 443906 CDS YP_001221913.1 148272352 5173715 complement(1338564..1339157) 1 NC_009480.1 putative DNA-3-methyladenine glycosylase I (3-methyladenine-DNA glycosylase I constitutive) (YP_061746.1| DNA-3-methyladenine glycosydase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629291.1| DNA-3-methyladenine glycosylase I [Streptomyces coelicolor A3(2)]). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. pfam03352, Adenine_glyco,Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA. tag: DNA-3-methyladenine glycosylase I; High confidence in function and specificity; putative DNA-3-methyladenine glycosylase I 1339157 tag 5173715 tag Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-3-methyladenine glycosylase I YP_001221913.1 1338564 R 443906 CDS YP_001221914.1 148272353 5175762 complement(1339154..1339618) 1 NC_009480.1 putative methylated-DNA--protein-cysteine methyltransferase (6-O- methylguanine-DNA methyltransferase) (YP_061747.1| methylated-DNA- protein-cysteine S-methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00267484.1| COG0350: Methylated DNA-protein cysteine methyltransferase [Pseudomonas fluorescens PfO-1]). pfam02870, Methyltransf_1N, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain. pfam01035, Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain.; High confidence in function and specificity; putative methylated-DNA--protein-cysteine methyltransferase 1339618 ogtB 5175762 ogtB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylated-DNA--protein-cysteine methyltransferase YP_001221914.1 1339154 R 443906 CDS YP_001221915.1 148272354 5175643 complement(1339881..1340360) 1 NC_009480.1 transcriptional regulatory protein, AsnC family (NP_823787.1| putative AsnC-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00059068.1| COG1522: Transcriptional regulators [Thermobifida fusca]). InterPro: Bacterial regulatory proteins AsnC family pfam01037, AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins.; Specificity unclear; AsnC family transcriptional regulator 1340360 5175643 CMM_1174 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AsnC family transcriptional regulator YP_001221915.1 1339881 R 443906 CDS YP_001221916.1 148272355 5175243 1340590..1341780 1 NC_009480.1 hypothetical protein containing putative FHA domain (YP_056718.1| hypothetical protein PPA2047 [Propionibacterium acnes KPA171202]).; hypothetical protein 1341780 5175243 CMM_1175 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221916.1 1340590 D 443906 CDS YP_001221917.1 148272356 5174714 1341777..1342613 1 NC_009480.1 putative protein serine/threonine phosphatase (YP_062154.1| protein phosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44187.1| protein phosphatase [Tropheryma whipplei str. Twist]). pfam00481, PP2C,Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase. InterPro: Protein phosphatase 2C domain.; Specificity unclear; putative protein serine/threonine phosphatase 1342613 5174714 CMM_1176 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein serine/threonine phosphatase YP_001221917.1 1341777 D 443906 CDS YP_001221918.1 148272357 5175936 complement(1342644..1343642) 1 NC_009480.1 putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase (YP_061899.1| 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226272.1| COG2171: Tetrahydrodipicolinate N-succinyltransferase [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase 1343642 dapD 5175936 dapD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase YP_001221918.1 1342644 R 443906 CDS YP_001221919.1 148272358 5174877 1343723..1344820 1 NC_009480.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; succinyl-diaminopimelate desuccinylase 1344820 dapE 5174877 dapE Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinyl-diaminopimelate desuccinylase YP_001221919.1 1343723 D 443906 CDS YP_001221920.1 148272359 5175801 1344802..1346034 1 NC_009480.1 conserved membrane protein (YP_061901.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789128.1| putative integral membrane protein [Tropheryma whipplei TW08/27]). mraY: phospho-N-acetylmuramoyl-pentape; Conserved hypothetical protein; hypothetical protein 1346034 5175801 CMM_1179 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221920.1 1344802 D 443906 CDS YP_001221921.1 148272360 5174405 1346182..1346355 1 NC_009480.1 conserved hypothetical protein (YP_061902.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301785.1| conserved hypothetical protein [Mycobacterium leprae TN]).; hypothetical protein 1346355 5174405 CMM_1180 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221921.1 1346182 D 443906 CDS YP_001221922.1 148272361 5175305 complement(1346465..1347097) 1 NC_009480.1 putative O-methyltransferase (YP_061903.1| O-methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227539.1| COG4122: Predicted O-methyltransferase [Kineococcus radiotolerans SRS30216]). pfam01596, Methyltransf_3, O-methyltransferase. Members of this family are O-methyltransferases. The family includes catechol o-methyl- transferase, caffeoyl-CoA O-methyltransferase and a family of bacterial O-methyltransferases that may be involved in antibiotic production. InterPro: O-methyltransferase (family 3) pts-sorbose: PTS system sorbose subfam; Specificity unclear; putative O-methyltransferase 1347097 5175305 CMM_1181 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative O-methyltransferase YP_001221922.1 1346465 R 443906 CDS YP_001221923.1 148272362 5175967 1347248..1347622 1 NC_009480.1 putative sec-independent protein translocase protein, twin arginine pathway (ZP_00227544.1| COG1826: Sec-independent protein secretion pathway components [Kineococcus radiotolerans SRS30216]; YP_055357.1| conserved protein, putative twin arginine translocation complex component [Propionibacterium acnes KPA171202]).; High confidence in function and specificity; putative sec-independent protein translocase protein, twin arginine pathway 1347622 tatB 5175967 tatB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sec-independent protein translocase protein, twin arginine pathway YP_001221923.1 1347248 D 443906 CDS YP_001221924.1 148272363 5175944 complement(1347668..1348585) 1 NC_009480.1 putative transcriptional regulator, LysR-family (NP_828178.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00226031.1| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 1348585 5175944 CMM_1183 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001221924.1 1347668 R 443906 CDS YP_001221925.1 148272364 5175820 1348665..1348823 1 NC_009480.1 hypothetical protein 1348823 5175820 CMM_1184 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221925.1 1348665 D 443906 CDS YP_001221926.1 148272365 5175211 complement(1348915..1350090) 1 NC_009480.1 putative ATP-binding protein (NP_301793.1| MRP-family ATP-binding protein [Mycobacterium leprae TN]; NP_939359.1| Putative ATP-binding protein [Corynebacterium diphtheriae NCTC 13129]). pfam00142, Fer4_NifH, 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family. contains a second N-terminal domain: pfam01883, DUF59,Domain of unknown function DUF59. This family includes prokaryotic proteins of unknown function. InterPro: Domain of unknown function DUF59; Function unclear; putative ATP-binding protein 1350090 5175211 CMM_1185 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-binding protein YP_001221926.1 1348915 R 443906 CDS YP_001221927.1 148272366 5175345 complement(1350080..1350628) 1 NC_009480.1 putative membrane protein (YP_061906.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824287.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam06210, DUF1003,Protein of unknown function (DUF1003). This family consists of several hypothetical bacterial proteins of unknown function.; Function unclear; hypothetical protein 1350628 5175345 CMM_1186 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221927.1 1350080 R 443906 CDS YP_001221928.1 148272367 5174948 complement(1350612..1351958) 1 NC_009480.1 putative Mg2+ transporter, MgtE family (YP_061907.1| protein containg CBS domains [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789177.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]). ,pfam03448, MgtE_N, MgtE intracellular domain. This domain is found in eubacterial magnesium transporters of the MgtE family pfam01769. This region of similarity is presumed to be an intracellular domain, that may be involved in magnesium binding. , pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; Specificity unclear; Mg2+ transporter 1351958 5174948 CMM_1187 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Mg2+ transporter YP_001221928.1 1350612 R 443906 CDS YP_001221929.1 148272368 5174127 1352017..1352685 1 NC_009480.1 conserved membrane protein (YP_061908.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737795.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 1352685 5174127 CMM_1188 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221929.1 1352017 D 443906 CDS YP_001221930.1 148272369 5174614 complement(1352714..1354336) 1 NC_009480.1 putative Xaa-Pro aminopeptidase (Aminopeptidase P I)(Aminoacylproline aminopeptidase I) (YP_061909.1| aminopeptidase P [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225551.1| COG0006: Xaa-Pro aminopeptidase [Kineococcus radiotolerans SRS30216]). , pfam05195, AMP_N,Aminopeptidase P, N-terminal domain. , pfam00557,Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative Xaa-Pro aminopeptidase 1354336 pepP2 5174614 pepP2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Xaa-Pro aminopeptidase YP_001221930.1 1352714 R 443906 CDS YP_001221931.1 148272370 5175069 complement(1354385..1355422) 1 NC_009480.1 putative membrane protein with hydrolase activity (NP_954765.1| hypothetical protein [Gordonia westfalica]; ZP_00120778.2| hypothetical protein Blon020650 [Bifidobacterium longum DJO10A]; NP_789235.1| putative integral membrane protein (possible nuclease activity)[Tropheryma whipplei TW08/27]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling (in C-terminal half of the protein).; Function unclear; putative membrane protein with hydrolase activity 1355422 5175069 CMM_1190 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane protein with hydrolase activity YP_001221931.1 1354385 R 443906 CDS YP_001221932.1 148272371 5175497 1355503..1356378 1 NC_009480.1 putative phosphoesterase (YP_061910.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225549.1| COG0613: Predicted metal-dependent phosphoesterases (PHP family) [Kineococcus radiotolerans SRS30216]). pfam02231, PHP_N, PHP domain N-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain.; Function unclear; hypothetical protein 1356378 5175497 CMM_1191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221932.1 1355503 D 443906 CDS YP_001221933.1 148272372 5175679 complement(1356467..1357996) 1 NC_009480.1 putative ATP dependant RNA helicase (YP_061912.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057513.1| COG0513: Superfamily II DNA and RNA helicases [Thermobifida fusca]; CAB08305.1| PROBABLE ATP-DEPENDENT RNA HELICASE RHLE [Mycobacterium tuberculosis H37Rv]). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; putative ATP-dependent RNA helicase 1357996 rhlE 5175679 rhlE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent RNA helicase YP_001221933.1 1356467 R 443906 CDS YP_001221934.1 148272373 5175758 1358104..1358865 1 NC_009480.1 conserved hypothetical protein (YP_061913.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629315.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1358865 5175758 CMM_1193 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221934.1 1358104 D 443906 CDS YP_001221935.1 148272374 5174235 complement(1358947..1359234) 1 NC_009480.1 putative membrane protein (YP_061914.1| hypothetical protein Lxx09200 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1359234 5174235 CMM_1194 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221935.1 1358947 R 443906 CDS YP_001221936.1 148272375 5174711 complement(1359244..1359468) 1 NC_009480.1 conserved hypothetical protein (NP_337832.1| hypothetical protein MT3304 [Mycobacterium tuberculosis CDC1551]; YP_061915.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1359468 5174711 CMM_1195 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221936.1 1359244 R 443906 CDS YP_001221937.1 148272376 5175303 1359662..1362931 1 NC_009480.1 putative ATP-dependant DNA helicase/nuclease (YP_061916.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291865.1| COG0210: Superfamily I DNA and RNA helicases [Thermobifida fusca]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. Some members have large insertions near to the carboxy-terminus relative to other members of the family. COG2887, RecB family exonuclease [DNA replication,recombination, and repair] domain at the C-terminus; Specificity unclear; putative ATP-dependant DNA helicase/nuclease 1362931 uvrD1 5175303 uvrD1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependant DNA helicase/nuclease YP_001221937.1 1359662 D 443906 CDS YP_001221938.1 148272377 5174809 1362928..1366203 1 NC_009480.1 putative ATP-dependent DNA helicase (YP_061917.1| ATP-dependent DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227594.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair] (C-terminal).; Specificity unclear; putative ATP-dependent DNA helicase 1366203 uvrD2 5174809 uvrD2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001221938.1 1362928 D 443906 CDS YP_001221939.1 148272378 5173514 complement(1366116..1367192) 1 NC_009480.1 putative phosphotransferase (YP_061918.1| macrolide 2'-phosphotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227597.1| COG3173: Predicted aminoglycoside phosphotransferase [Kineococcus radiotolerans SRS30216]). pfam01636, APH, Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins, which confer resistance to various aminoglycosides. degV: degV family protein; Specificity unclear; putative phosphotransferase 1367192 5173514 CMM_1198 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphotransferase YP_001221939.1 1366116 R 443906 CDS YP_001221940.1 148272379 5174766 1367328..1368281 1 NC_009480.1 putative NTP pyrophosphohydrolase (YP_061919.1| NADH pyrophosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227598.1| COG2816: NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid- binding [Kineococcus radiotolerans SRS30216]). pfam00293, NUDIX, NUDIX domain.; Specificity unclear; putative NTP pyrophosphohydrolase 1368281 5174766 CMM_1199 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphohydrolase YP_001221940.1 1367328 D 443906 CDS YP_001221941.1 148272380 5174330 1368292..1370205 1 NC_009480.1 putative ATP-dependent DNA helicase (YP_061920.1| ATP-dependent DNA helicase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227601.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. InterPro: UvrD/REP helicase.; Specificity unclear; putative ATP-dependent DNA helicase 1370205 uvrD3 5174330 uvrD3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001221941.1 1368292 D 443906 CDS YP_001221942.1 148272381 5173941 complement(1370069..1370956) 1 NC_009480.1 conserved hypothetical protein (CAA16661.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_939100.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]). bcl-2: Apoptosis regulator; hypothetical protein 1370956 5173941 CMM_1201 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221942.1 1370069 R 443906 CDS YP_001221943.1 148272382 5174447 complement(1371099..1372502) 1 NC_009480.1 conserved hypothetical protein (YP_061922.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824237.1| hypothetical protein SAV3061 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1372502 5174447 CMM_1202 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221943.1 1371099 R 443906 CDS YP_001221944.1 148272383 5175671 1372715..1373806 1 NC_009480.1 putative ATP-dependant serine protease protein containing a PDZ domain, family S16 (ZP_00227615.1| COG3480: Predicted secreted protein containing a PDZ domain [Kineococcus radiotolerans SRS30216]; YP_061923.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins. , pfam05362, Lon_C, Lon protease (S16) C-terminal proteolytic domain. The Lon serine proteases must hydrolyse ATP to degrade protein substrates.; Function unclear; ATP-dependant serine protease 1373806 5175671 CMM_1203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependant serine protease YP_001221944.1 1372715 D 443906 CDS YP_001221945.1 148272384 5174523 1373947..1376898 1 NC_009480.1 conseved membrane protein (YP_061924.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789569.1| putative integral membrane protein [Tropheryma whipplei TW08/27]). TIGR00367: K+-dependent Na+/Ca+ exchan; conseved membrane protein 1376898 5174523 CMM_1204 Clavibacter michiganensis subsp. michiganensis NCPPB 382 conseved membrane protein YP_001221945.1 1373947 D 443906 CDS YP_001221946.1 148272385 5175242 complement(1377208..1377873) 1 NC_009480.1 putative peroxiredoxin (NP_624490.1| hypothetical protein SCJ1.03c [Streptomyces coelicolor A3(2)]; ZP_00092626.1| COG1225: Peroxiredoxin [Azotobacter vinelandii]). pfam00578, AhpC-TSA, AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Specificity unclear; putative peroxiredoxin 1377873 5175242 CMM_1205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peroxiredoxin YP_001221946.1 1377208 R 443906 CDS YP_001221947.1 148272386 5174647 complement(1377992..1379713) 1 NC_009480.1 conserved hypothetical protein, putative protein kinase (ZP_00017319.1| hypothetical protein [Chloroflexus aurantiacus]; ZP_00112431.1| COG0661: Predicted unusual protein kinase [Nostoc punctiforme]). , pfam03109, ABC1,ABC1 family.; Function unclear; putative protein kinase 1379713 5174647 CMM_1206 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein kinase YP_001221947.1 1377992 R 443906 CDS YP_001221948.1 148272387 5173390 complement(1379710..1380282) 1 NC_009480.1 putative transcriptional regulator, PadR family (NP_625650.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959288.1| hypothetical protein MAP0354c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03551, PadR, Transcriptional regulator PadR-like family.; Specificity unclear; PadR family transcriptional regulator 1380282 5173390 CMM_1207 Clavibacter michiganensis subsp. michiganensis NCPPB 382 PadR family transcriptional regulator YP_001221948.1 1379710 R 443906 CDS YP_001221949.1 148272388 5174720 complement(1380411..1381406) 1 NC_009480.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1381406 lipA 5174720 lipA Clavibacter michiganensis subsp. michiganensis NCPPB 382 lipoyl synthase YP_001221949.1 1380411 R 443906 CDS YP_001221950.1 148272389 5173747 complement(1381403..1382104) 1 NC_009480.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 1382104 lipB 5173747 lipB Clavibacter michiganensis subsp. michiganensis NCPPB 382 lipoate-protein ligase B YP_001221950.1 1381403 R 443906 CDS YP_001221951.1 148272390 5173817 1382208..1383107 1 NC_009480.1 putative siderophore-interacting protein (NP_625898.1| conserved hypothetical protein SCI41.06 [Streptomyces coelicolor A3(2)]; NP_337475.1| siderophore utilization protein [Mycobacterium tuberculosis CDC1551]). pfam04954, SIP, Siderophore-interacting protein.; Specificity unclear; putative siderophore-interacting protein 1383107 5173817 CMM_1210 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative siderophore-interacting protein YP_001221951.1 1382208 D 443906 CDS YP_001221952.1 148272391 5174319 1383261..1383848 1 NC_009480.1 hypothetical protein 1383848 5174319 CMM_1211 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221952.1 1383261 D 443906 CDS YP_001221953.1 148272392 5174231 1383874..1384521 1 NC_009480.1 hypothetical protein 1384521 5174231 CMM_1212 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221953.1 1383874 D 443906 CDS YP_001221954.1 148272393 5174068 1384572..1385234 1 NC_009480.1 conserved membrane protein (YP_051757.1| putative membrane protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00228341.1| COG1284: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam02588, DUF161, Uncharacterized BCR, YitT family COG1284. This is probably a bacterial ABC transporter permease (personal obs:Yeats C) (twice).; Function unclear; hypothetical protein 1385234 5174068 CMM_1213 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221954.1 1384572 D 443906 CDS YP_001221955.1 148272394 5173933 complement(1385245..1385583) 1 NC_009480.1 putative membrane protein (AAM35479.1| inner membrane protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00226239.1| COG1299: Phosphotransferase system,fructose-specific IIC component [Kineococcus radiotolerans SRS30216]). bcl-2: Apoptosis regulator; Hypothetical protein; hypothetical protein 1385583 5173933 CMM_1214 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221955.1 1385245 R 443906 CDS YP_001221956.1 148272395 5173719 1386030..1389488 1 NC_009480.1 hypothetical protein 1389488 5173719 CMM_1215 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221956.1 1386030 D 443906 CDS YP_001221957.1 148272396 5175032 complement(1389546..1390244) 1 NC_009480.1 putative cation efflux protein, CDF family (BAD34981.1| hypothetical protein [Arthrobacter globiformis]; ZP_00227400.1| COG0053: Predicted Co/Zn/Cd cation transporters [Kineococcus radiotolerans SRS30216]). pfam01545, Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; Function unclear; CDF family cation efflux protein 1390244 5175032 CMM_1216 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CDF family cation efflux protein YP_001221957.1 1389546 R 443906 CDS YP_001221958.1 148272397 5174676 complement(1390241..1390594) 1 NC_009480.1 putative transcriptional regulator, ArsR family (NP_600134.1| predicted arsR family transcriptional regulator [Corynebacterium glutamicum ATCC 13032]; H70757 probable transcription regulator - Mycobacterium tuberculosis (strain H37RV)). pfam01022, HTH_5, Bacterial regulatory protein, arsR family.; Specificity unclear; ArsR family transcriptional regulator 1390594 5174676 CMM_1217 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ArsR family transcriptional regulator YP_001221958.1 1390241 R 443906 CDS YP_001221959.1 148272398 5175793 1390705..1391142 1 NC_009480.1 putative arsenate reductase (NP_898754.1| putative arsenate reductase (ArsC) [Rhodococcus erythropolis]; CAF21520.1| Low molecular weight phosphotyrosine protein phosphatase [Corynebacterium glutamicum ATCC 13032]). pfam01451, LMWPc, Low molecular weight phosphotyrosine protein phosphatase. InterPro: Low molecular weight phosphotyrosine protein phosphatase.; Function unclear; hypothetical protein 1391142 5175793 CMM_1218 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221959.1 1390705 D 443906 CDS YP_001221960.1 148272399 5175921 complement(1391174..1391800) 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00188267.2| COG1309: Transcriptional regulator [Rubrobacter xylanophilus DSM 9941]; G69677 transcription regulator of polyketide synthase operon pksA - Bacillus subtilis). InterPro: Bacterial regulatory proteins TetR family pfam00440, TetR_N, Bacterial regulatory proteins,tetR family.; Specificity unclear; TetR family transcriptional regulator 1391800 5175921 CMM_1219 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001221960.1 1391174 R 443906 CDS YP_001221961.1 148272400 5175781 1391878..1393194 1 NC_009480.1 putative carboxylesterase (B69680 para-nitrobenzyl esterase (EC 3.1.1.-) - Bacillus subtilis; AAP03116.1| putative carboxyesterase [Streptomyces griseochromogenes]). pfam00135, COesterase,Carboxylesterase.; Specificity unclear; putative carboxylesterase 1393194 5175781 CMM_1220 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxylesterase YP_001221961.1 1391878 D 443906 CDS YP_001221962.1 148272401 5175952 1393337..1394131 1 NC_009480.1 hypothetical protein 1394131 5175952 CMM_1221 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221962.1 1393337 D 443906 CDS YP_001221963.1 148272402 5175604 complement(1394148..1395008) 1 NC_009480.1 putative hydrolase (NP_301650.1| putative oxidoreductase [Mycobacterium leprae TN]; NP_627387.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. ispD: 4-diphosphocytidyl-2C-methyl-D-er; Function unclear; putative hydrolase 1395008 5175604 CMM_1222 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001221963.1 1394148 R 443906 CDS YP_001221964.1 148272403 5175435 complement(1395005..1395571) 1 NC_009480.1 putative acetyltransferase (YP_061542.1| acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826247.1| putative acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1395571 5175435 CMM_1223 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001221964.1 1395005 R 443906 CDS YP_001221965.1 148272404 5175634 1395742..1395936 1 NC_009480.1 Hypothetical protein; hypothetical protein 1395936 5175634 CMM_1224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221965.1 1395742 D 443906 CDS YP_001221966.1 148272405 5175128 complement(1396033..1397793) 1 NC_009480.1 putative ATP-dependent RNA helicase (YP_062280.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; CAB00899.1| PROBABLE COLD-SHOCK DEAD-BOX PROTEIN A HOMOLOG DEAD (ATP-dependent RNA helicase deaD homolog) [Mycobacterium tuberculosis H37Rv]). Cold-shock DEAD-box protein A homolog (ATP-dependent RNA helicase deaD homolog). Has a helix-destabilizing activity (By similarity). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. pfam00271, Helicase_C, Helicase conserved C-terminal domain. pfam03880, DbpA, DbpA RNA binding domain. This RNA binding domain is found at the C-terminus of a number of DEAD helicase proteins.; Function unclear; putative ATP-dependent RNA helicase 1397793 5175128 CMM_1225 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent RNA helicase YP_001221966.1 1396033 R 443906 CDS YP_001221967.1 148272406 5174532 complement(1397886..1398641) 1 NC_009480.1 Hypothetical protein; hypothetical protein 1398641 5174532 CMM_1226 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221967.1 1397886 R 443906 CDS YP_001221968.1 148272407 5174974 complement(1398721..1399578) 1 NC_009480.1 putative methyltransferase (NP_823028.1| hypothetical protein SAV1852 [Streptomyces avermitilis MA-4680]; ZP_00225290.1| COG4106: Trans-aconitate methyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; putative methyltransferase 1399578 5174974 CMM_1227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001221968.1 1398721 R 443906 CDS YP_001221969.1 148272408 5174157 1399626..1400255 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (ZP_00210190.1| COG1396: Predicted transcriptional regulators [Magnetospirillum magnetotacticum]; ZP_00225291.2| COG1396: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 1400255 5174157 CMM_1228 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001221969.1 1399626 D 443906 CDS YP_001221970.1 148272409 5173620 complement(1400252..1401739) 1 NC_009480.1 hypothetical membrane protein , pfam03793, PASTA,PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases.; Hypothetical protein; hypothetical protein 1401739 5173620 CMM_1229 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221970.1 1400252 R 443906 CDS YP_001221971.1 148272410 5173505 complement(1401878..1402093) 1 NC_009480.1 hypothetical protein 1402093 5173505 CMM_1230 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221971.1 1401878 R 443906 CDS YP_001221972.1 148272411 5174020 complement(1402248..1402871) 1 NC_009480.1 putative carboxylesterase/phospholipase (ZP_00048910.1| COG0400: Predicted esterase [Magnetospirillum magnetotacticum]; NP_769886.1| bll3246 [Bradyrhizobium japonicum USDA 110]). pfam02230,Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity. InterPro: Phospholipase/Carboxylesterase; Function unclear; putative carboxylesterase/phospholipase 1402871 5174020 CMM_1231 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxylesterase/phospholipase YP_001221972.1 1402248 R 443906 CDS YP_001221973.1 148272412 5173429 complement(1402868..1403845) 1 NC_009480.1 putative dioxygenase (NP_769887.1| dioxygenase [Bradyrhizobium japonicum USDA 110]; ZP_00007110.1| COG0346: Lactoylglutathione lyase and related lyases [Rhodobacter sphaeroides]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (twice). InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; putative dioxygenase 1403845 5173429 CMM_1232 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dioxygenase YP_001221973.1 1402868 R 443906 CDS YP_001221974.1 148272413 5173881 complement(1403907..1404470) 1 NC_009480.1 hypothetical protein 1404470 5173881 CMM_1233 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221974.1 1403907 R 443906 CDS YP_001221975.1 148272414 5175421 1404553..1405680 1 NC_009480.1 Hypothetical protein; hypothetical protein 1405680 5175421 CMM_1234 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221975.1 1404553 D 443906 CDS YP_001221976.1 148272415 5173327 complement(1405686..1406126) 1 NC_009480.1 conserved hypothetical protein (ZP_00186867.2| hypothetical protein Rxyl021934 [Rubrobacter xylanophilus DSM 9941]; YP_062966.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1406126 5173327 CMM_1235 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221976.1 1405686 R 443906 CDS YP_001221977.1 148272416 5173098 1406232..1406501 1 NC_009480.1 hypothetical protein 1406501 5173098 CMM_1236 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221977.1 1406232 D 443906 CDS YP_001221978.1 148272417 5173260 1406568..1407698 1 NC_009480.1 putative NDP-sugar phosphate epimerase (ZP_00126896.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Pseudomonas syringae pv. syringae B728a]; ZP_00227125.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; CAC80137.1| progesterone 5-beta-reductase [Digitalis purpurea]).; Function unclear; putative NDP-sugar phosphate epimerase 1407698 5173260 CMM_1237 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NDP-sugar phosphate epimerase YP_001221978.1 1406568 D 443906 CDS YP_001221979.1 148272418 5172941 complement(1407685..1408923) 1 NC_009480.1 conserved membrane protein (ZP_00057288.1| COG2311: Predicted membrane protein [Thermobifida fusca]; CAF20253.1| putative membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam04171, DUF405, Protein of unknown function (DUF405). Predicted to be an integral membrane protein. pfam04235, DUF418, Protein of unknown function (DUF418). Probable integral membrane protein.; Function unclear; hypothetical protein 1408923 5172941 CMM_1238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221979.1 1407685 R 443906 CDS YP_001221980.1 148272419 5172952 1409053..1409979 1 NC_009480.1 putative multidrug ABC transporter, ATPase component (ZP_00227246.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_626193.1| putative ABC transporter, ATP-binding subunit [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative multidrug ABC transporter, ATPase component 1409979 5172952 CMM_1239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug ABC transporter, ATPase component YP_001221980.1 1409053 D 443906 CDS YP_001221981.1 148272420 5175691 1409976..1410839 1 NC_009480.1 putative multidrug ABC transporter, permease component (ZP_00227245.1| COG0842: ABC-type multidrug transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_827497.1| putative integral membrane transport protein [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative multidrug ABC transporter, permease component 1410839 5175691 CMM_1240 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug ABC transporter, permease component YP_001221981.1 1409976 D 443906 CDS YP_001221982.1 148272421 5173526 1410843..1412144 1 NC_009480.1 putative two-component system, sensor kinase (AAD45902.1| histidine kinase ChrS [Corynebacterium diphtheriae]; YP_061777.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1412144 5173526 CMM_1241 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001221982.1 1410843 D 443906 CDS YP_001221983.1 148272422 5173329 1412141..1412815 1 NC_009480.1 putative two-component system, response regulator (ZP_00200243.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Rubrobacter xylanophilus DSM 9941]; NP_294711.1| DNA-binding response regulator [Deinococcus radiodurans R1]). cd00156, REC, Signal receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1412815 5173329 CMM_1242 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001221983.1 1412141 D 443906 CDS YP_001221984.1 148272423 5174040 1413116..1414258 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (NP_244309.1| multiple sugar transport system (multiple sugar-binding protein) [Bacillus halodurans C-125]; AAN25480.1| probable sugar binding protein of ABC transporter for pentoses [Bifidobacterium longum NCC2705]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 1414258 5174040 CMM_1243 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001221984.1 1413116 D 443906 CDS YP_001221985.1 148272424 5174554 1414382..1415926 1 NC_009480.1 putative sugar ABC transporter, ATP-binding protein (ZP_00225839.1| COG1129: ABC-type sugar transport system,ATPase component [Kineococcus radiotolerans SRS30216]; NP_626651.1| putative sugar-transport ATP binding protein [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter(twice).; Specificity unclear; putative sugar ABC transporter, ATP-binding protein 1415926 5174554 CMM_1244 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATP-binding protein YP_001221985.1 1414382 D 443906 CDS YP_001221986.1 148272425 5174471 1415923..1417131 1 NC_009480.1 putative sugar ABC transporter, permease component (YP_061240.1| L-arabinose ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121446.1| COG4214: ABC-type xylose transport system,permease component [Bifidobacterium longum DJO10A]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter, permease component 1417131 5174471 CMM_1245 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001221986.1 1415923 D 443906 CDS YP_001221987.1 148272426 5174433 1417252..1417536 1 NC_009480.1 hypothetical protein 1417536 5174433 CMM_1246 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221987.1 1417252 D 443906 CDS YP_001221988.1 148272427 5175396 complement(1417546..1418346) 1 NC_009480.1 putative signal peptidase I (Leader peptidase I) (ZP_00293226.1| COG0681: Signal peptidase I [Thermobifida fusca]; AAT59376.1| signal peptidase I [Bacillus thuringiensis serovar konkukian str. 97-27]). pfam00461,Peptidase_S26, Signal peptidase I.; Specificity unclear; putative signal peptidase I 1418346 sipX 5175396 sipX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative signal peptidase I YP_001221988.1 1417546 R 443906 CDS YP_001221989.1 148272428 5174081 complement(1418373..1419275) 1 NC_009480.1 hypothetical protein 1419275 5174081 CMM_1248 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221989.1 1418373 R 443906 CDS YP_001221990.1 148272429 5174992 complement(1419272..1419874) 1 NC_009480.1 hypothetical secreted protein (only weak similarity to: AAP08264.1| Cell envelope-bound metalloprotease (camelysin) [Bacillus cereus ATCC 14579]; ZP_00293230.1| hypothetical protein Tfus02001419 [Thermobifida fusca]).; hypothetical protein 1419874 5174992 CMM_1249 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221990.1 1419272 R 443906 CDS YP_001221991.1 148272430 5175905 complement(1419971..1420516) 1 NC_009480.1 hypothetical secreted protein (NP_737798.1| hypothetical protein [Corynebacterium efficiens YS-314];).; hypothetical protein 1420516 5175905 CMM_1250 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221991.1 1419971 R 443906 CDS YP_001221992.1 148272431 5174424 1420874..1422520 1 NC_009480.1 putative two-component system, sensor histidine kinase (ZP_00200781.1| COG0642: Signal transduction histidine kinase [Exiguobacterium sp. 255-15]; ZP_00236041.1| sensory box histidine kinase PhoR [Bacillus cereus G9241]). smart00388, HisKA, His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor histidine kinase 1422520 5174424 CMM_1251 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor histidine kinase YP_001221992.1 1420874 D 443906 CDS YP_001221993.1 148272432 5174962 1422657..1424486 1 NC_009480.1 putative choline/glycine/betaine transporter, BCCT family (AAN69228.1| choline/carnitine/betaine transporter family protein [Pseudomonas putida KT2440]; CAB40689.1| putative BCCT family transporter [Streptomyces coelicolor A3(2)]). pfam02028, BCCT, BCCT family transporter. bcct: choline/carnitine/betaine transp; Specificity unclear; BCCT family choline/glycine betaine transporter 1424486 5174962 CMM_1252 Clavibacter michiganensis subsp. michiganensis NCPPB 382 BCCT family choline/glycine betaine transporter YP_001221993.1 1422657 D 443906 CDS YP_001221994.1 148272433 5174598 1424616..1425632 1 NC_009480.1 putative diacylglycerol kinase (YP_055799.1| conserved protein with diacylglycerol kinase catalytic domain [Propionibacterium acnes KPA171202]; YP_062988.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; Function unclear; putative diacylglycerol kinase 1425632 5174598 CMM_1253 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative diacylglycerol kinase YP_001221994.1 1424616 D 443906 CDS YP_001221995.1 148272434 5174288 1425688..1426866 1 NC_009480.1 putative ATPase (NP_719329.1| conserved hypothetical protein [Shewanella oneidensis MR-1]; ZP_00262873.1| COG4637: Predicted ATPase [Pseudomonas fluorescens PfO-1]).; Function unclear; putative ATPase 1426866 5174288 CMM_1254 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001221995.1 1425688 D 443906 CDS YP_001221996.1 148272435 5173422 complement(1426991..1428094) 1 NC_009480.1 putative fatty acid desaturase (NP_631110.1| putative delta fatty acid desaturase [Streptomyces coelicolor A3(2)]; ZP_00190195.3| COG3239: Fatty acid desaturase [Kineococcus radiotolerans SRS30216]) Fatty acid desaturase with both delta-5 and delta-6 activities. May represent a component of the polyunsaturated fatty acid biosynthesis pathway. pfam00487, FA_desaturase, Fatty acid desaturase.; Specificity unclear; putative fatty acid desaturase 1428094 5173422 CMM_1255 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative fatty acid desaturase YP_001221996.1 1426991 R 443906 CDS YP_001221997.1 148272436 5173864 complement(1428412..1429455) 1 NC_009480.1 putative Zn-dependent alcohol dehydrogenase (NP_631415.1| oxidoreductase. [Streptomyces coelicolor A3(2)]; AAN73270.1| (S)-specific alcohol dehydrogenase [Rhodococcus erythropolis]). , pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependent alcohol dehydrogenase 1429455 5173864 CMM_1256 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependent alcohol dehydrogenase YP_001221997.1 1428412 R 443906 CDS YP_001221998.1 148272437 5173304 complement(1429505..1430248) 1 NC_009480.1 Hypothetical protein; hypothetical protein 1430248 5173304 CMM_1257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221998.1 1429505 R 443906 CDS YP_001221999.1 148272438 5173359 1430413..1431060 1 NC_009480.1 conserved hypothetical protein (NP_627213.1| conserved hypothetical protein SCE50.18c [Streptomyces coelicolor A3(2)]; ZP_00225215.2| hypothetical protein Krad06002218 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1431060 5173359 CMM_1258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001221999.1 1430413 D 443906 CDS YP_001222000.1 148272439 5173411 complement(1431088..1434114) 1 NC_009480.1 putative alpha-mannosidase (Alpha-D-mannoside mannohydrolase) (NP_828453.1| putative alpha-mannosidase [Streptomyces avermitilis MA-4680]; YP_056165.1| alpha-mannosidase [Propionibacterium acnes KPA171202]). pfam01074, Glyco_hydro_38, Glycosyl hydrolases family 38.; High confidence in function and specificity; putative alpha-mannosidase 1434114 5173411 CMM_1259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-mannosidase YP_001222000.1 1431088 R 443906 CDS YP_001222001.1 148272440 5172940 complement(1434234..1435142) 1 NC_009480.1 putative sugar ABC transporter, permease component (YP_061256.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629566.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 1435142 5172940 CMM_1260 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001222001.1 1434234 R 443906 CDS YP_001222002.1 148272441 5173985 complement(1435145..1436149) 1 NC_009480.1 putative sugar ABC transporter, permease component (YP_061255.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228402.1| COG1175: ABC-type sugar transport systems, permease components [Kineococcus radiotolerans SRS30216]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative sugar ABC transporter, permease component 1436149 5173985 CMM_1261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001222002.1 1435145 R 443906 CDS YP_001222003.1 148272442 5172987 complement(1436152..1437543) 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (NP_629568.1| putative extracellular solute-binding lipoprotein [Streptomyces coelicolor A3(2)]; ZP_00228401.1| COG1653: ABC-type sugar transport system,periplasmic component [Kineococcus radiotolerans SRS30216]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate binding protein 1437543 5172987 CMM_1262 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001222003.1 1436152 R 443906 CDS YP_001222004.1 148272443 5174265 complement(1437721..1438986) 1 NC_009480.1 putative transcriptional regulator, Rok family (YP_061254.1| transcriptional regulator, ROK family [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00191333.2| COG1940: Transcriptional regulator/sugar kinase [Kineococcus radiotolerans SRS30216]). pfam00480, ROK, ROK family. ROK_glcA_fam: ROK family protein (puta; Specificity unclear; ROK family transcriptional regulator 1438986 5174265 CMM_1263 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ROK family transcriptional regulator YP_001222004.1 1437721 R 443906 CDS YP_001222005.1 148272444 5173573 1439158..1440297 1 NC_009480.1 conserved hypothetical protein (NP_625062.1| hypothetical protein SCF81.18 [Streptomyces coelicolor A3(2)]; ZP_00225772.1| hypothetical protein Krad06004462 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1440297 5173573 CMM_1264 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222005.1 1439158 D 443906 CDS YP_001222006.1 148272445 5173892 1440294..1440596 1 NC_009480.1 conserved secreted protein (ZP_00238872.1| conserved protein [Bacillus cereus G9241]; ZP_00274962.1| COG3369: Uncharacterized conserved protein [Ralstonia metallidurans CH34]).; Conserved hypothetical protein; hypothetical protein 1440596 5173892 CMM_1265 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222006.1 1440294 D 443906 CDS YP_001222007.1 148272446 5173034 complement(1440613..1441524) 1 NC_009480.1 putative Zn-metalloprotease (NP_959994.1| hypothetical protein MAP1060c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00227674.1| COG2321: Predicted metalloprotease [Kineococcus radiotolerans SRS30216]). pfam04228, Zn_peptidase, Putative neutral zinc metallopeptidase. Members of this family have a predicted zinc binding motif characteristic of neutral zinc metallopeptidases.; Function unclear; putative Zn-metalloprotease 1441524 5173034 CMM_1266 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-metalloprotease YP_001222007.1 1440613 R 443906 CDS YP_001222008.1 148272447 5175500 complement(1441556..1442185) 1 NC_009480.1 putative DNA alkylation repair enzyme (weak similarity; NP_899834.1| DNA alkylation repair enzyme [Chromobacterium violaceum ATCC 12472]; NP_720542.1| DNA alkylation repair enzyme [Streptococcus mutans UA159]). possibly COG4912: Predicted DNA alkylation repair enzyme; Conserved hypothetical protein; putative DNA alkylation repair enzyme 1442185 5175500 CMM_1267 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA alkylation repair enzyme YP_001222008.1 1441556 R 443906 CDS YP_001222009.1 148272448 5173883 complement(1442182..1443195) 1 NC_009480.1 putative NAD-dependant epimerase (NP_736669.1| hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00227493.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Specificity unclear; putative NAD-dependant epimerase 1443195 5173883 CMM_1268 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD-dependant epimerase YP_001222009.1 1442182 R 443906 CDS YP_001222010.1 148272449 5175142 complement(1443309..1443824) 1 NC_009480.1 conserved hypothetical protein (YP_062270.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294009.1| hypothetical protein Tfus02000211 [Thermobifida fusca]).; hypothetical protein 1443824 5175142 CMM_1269 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222010.1 1443309 R 443906 CDS YP_001222011.1 148272450 5175304 complement(1443821..1444195) 1 NC_009480.1 putative ATP-dependent Clp protease adaptor protein (YP_062269.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; Q9S2G5|CLPS_STRCO ATP-dependent Clp protease adaptor protein clpS). pfam02617,ClpS, ATP-dependent Clp protease adaptor protein ClpS. In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. ClpS directly influences the ClpAP machine by binding to the N-terminal domain of the chaperone ClpA.; High confidence in function and specificity; putative ATP-dependent Clp protease adaptor protein 1444195 clpS 5175304 clpS Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent Clp protease adaptor protein YP_001222011.1 1443821 R 443906 CDS YP_001222012.1 148272451 5174381 complement(1444284..1444982) 1 NC_009480.1 putative two-component system, response regulator (ZP_00228547.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; YP_061872.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system, response regulator 1444982 5174381 CMM_1271 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001222012.1 1444284 R 443906 CDS YP_001222013.1 148272452 5174545 complement(1444979..1446223) 1 NC_009480.1 putative two-component system sensor kinase (YP_061873.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627597.1| putative two component sensor kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 1446223 5174545 CMM_1272 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001222013.1 1444979 R 443906 CDS YP_001222014.1 148272453 5174669 complement(1446319..1447158) 1 NC_009480.1 putative ABC transporter, permease component (YP_061874.1| ABC transporter, integral membrane subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198462.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). weak similarity to: COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only] lspA: lipoprotein signal peptidase; Function unclear; putative ABC transporter, permease component 1447158 5174669 CMM_1273 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, permease component YP_001222014.1 1446319 R 443906 CDS YP_001222015.1 148272454 5174890 complement(1447155..1448090) 1 NC_009480.1 putative multidrug ABC transporter, ATP-binding protein (YP_061875.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737963.1| putative transport ATP-binding protein [Corynebacterium efficiens YS-314]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative multidrug ABC transporter, ATP-binding protein 1448090 5174890 CMM_1274 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug ABC transporter, ATP-binding protein YP_001222015.1 1447155 R 443906 CDS YP_001222016.1 148272455 5174146 complement(1448221..1449426) 1 NC_009480.1 putative aminotransferase (ZP_00225649.1| COG0436: Aspartate/tyrosine/ aromatic aminotransferase [Kineococcus radiotolerans SRS30216]; NP_825694.1| putative aminotransferase [Streptomyces avermitilis MA-4680]). pfam00155, Aminotran_1_2, Aminotransferase class I and II. InterPro: Aminotransferases class-I; Specificity unclear; putative aminotransferase 1449426 5174146 CMM_1275 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aminotransferase YP_001222016.1 1448221 R 443906 CDS YP_001222017.1 148272456 5174147 1449499..1450152 1 NC_009480.1 hypothetical protein (ZP_00228066.1| hypothetical protein Krad06002257 [Kineococcus radiotolerans SRS30216]; NP_629174.1| putative lipoprotein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1450152 5174147 CMM_1276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222017.1 1449499 D 443906 CDS YP_001222018.1 148272457 5175320 1450416..1451048 1 NC_009480.1 hypothetical protein (ZP_00188960.2| hypothetical protein Krad06004713 [Kineococcus radiotolerans SRS30216]; NP_789426.1| hypothetical protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1451048 5175320 CMM_1277 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222018.1 1450416 D 443906 CDS YP_001222019.1 148272458 5173858 1451273..1452808 1 NC_009480.1 putative serine protease (NP_737560.1| putative serine protease, heat shock protein [Corynebacterium efficiens YS-314]; YP_062302.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00089,Trypsin, Trypsin. pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins. InterPro: Serine proteases trypsin family.; Function unclear; putative serine protease 1452808 5173858 CMM_1278 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine protease YP_001222019.1 1451273 D 443906 CDS YP_001222020.1 148272459 5174908 1452959..1454032 1 NC_009480.1 putative glycosyl transferase (YP_062303.1| glucosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826208.1| putative glycosyl transferase [Streptomyces avermitilis MA-4680]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 1454032 5174908 CMM_1279 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001222020.1 1452959 D 443906 CDS YP_001222021.1 148272460 5175866 1454029..1454850 1 NC_009480.1 putative transferase, putative phosphatidylglycerophosphate synthase (YP_062304.1| transferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293849.1| COG0558: Phosphatidylglycerophosphate synthase [Thermobifida fusca]).; Specificity unclear; putative transferase, putative phosphatidylglycerophosphate synthase 1454850 5175866 CMM_1280 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transferase, putative phosphatidylglycerophosphate synthase YP_001222021.1 1454029 D 443906 CDS YP_001222022.1 148272461 5175570 1454847..1455722 1 NC_009480.1 putative glycosyl transferase (YP_062305.1| glycosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630828.1| putative glycosyltransferase [Streptomyces coelicolor A3(2)]). pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 1455722 5175570 CMM_1281 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001222022.1 1454847 D 443906 CDS YP_001222023.1 148272462 5175122 1455820..1457106 1 NC_009480.1 putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (Polyglycerol phosphate polymerase) (YP_062607.1| teichoic acid synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_267077.1| teichoic acid biosynthesis protein [Lactococcus lactis subsp. lactis Il1403]). pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerisation of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.; Function unclear; putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase 1457106 5175122 CMM_1282 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001222023.1 1455820 D 443906 CDS YP_001222024.1 148272463 5174565 complement(1457153..1457902) 1 NC_009480.1 conserved membrane protein (YP_062301.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301803.1| putative membrane protein [Mycobacterium leprae]).; hypothetical protein 1457902 5174565 CMM_1283 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222024.1 1457153 R 443906 CDS YP_001222025.1 148272464 5174321 1458057..1458380 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (CAD12221.1| hypothetical protein [Corynebacterium glutamicum]; AAN62096.1| conserved hypothetical protein [Pseudomonas aeruginosa]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 1458380 5174321 CMM_1284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001222025.1 1458057 D 443906 CDS YP_001222026.1 148272465 5173910 complement(1458370..1458681) 1 NC_009480.1 hypothetical protein (YP_062300.1| hypothetical protein Lxx13690 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1458681 5173910 CMM_1285 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222026.1 1458370 R 443906 CDS YP_001222027.1 148272466 5173590 complement(1458766..1459545) 1 NC_009480.1 putative polysaccharide/polyol phosphate ABC transporter, ATP-binding protein (YP_062299.1| lipopolysaccharide exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058569.1| COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Thermobifida fusca]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative polysaccharide/polyol phosphate ABC transporter, ATP-binding protein 1459545 5173590 CMM_1286 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polysaccharide/polyol phosphate ABC transporter, ATP-binding protein YP_001222027.1 1458766 R 443906 CDS YP_001222028.1 148272467 5175198 complement(1459545..1460345) 1 NC_009480.1 putative polysaccharide/polyol phosphate ABC transporter, permease component (YP_062298.1| lipopolysaccharide exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058570.1| COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component [Thermobifida fusca]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam01061, ABC2_membrane,ABC-2 type transporter.; Specificity unclear; putative polysaccharide/polyol phosphate ABC transporter, permease component 1460345 tagG 5175198 tagG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polysaccharide/polyol phosphate ABC transporter, permease component YP_001222028.1 1459545 R 443906 CDS YP_001222029.1 148272468 5174500 complement(1460382..1461074) 1 NC_009480.1 putative sugar nucleotidyltransferase (ZP_00226670.1| COG1213: Predicted sugar nucleotidyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00058566.1| COG1213: Predicted sugar nucleotidyltransferases [Thermobifida fusca]; NP_810634.1| putative glucose-1-P -cytidylyltransferase [Bacteroides thetaiotaomicron VPI-5482]). MAYBE INVOLVED IN THE BIOSYNTHESIS OF TEICHOIC ACIDS. pfam00483,NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; Specificity unclear; putative sugar nucleotidyltransferase 1461074 5174500 CMM_1288 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar nucleotidyltransferase YP_001222029.1 1460382 R 443906 CDS YP_001222030.1 148272469 5175006 1462342..1463223 1 NC_009480.1 putative ABC transporter, ATP-binding protein (YP_062297.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; cNP_696828.1| ATP-binding protein of ABC transporter system [Bifidobacterium longum NCC2705]). pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative ABC transporter, ATP-binding protein 1463223 5175006 CMM_1289 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001222030.1 1462342 D 443906 CDS YP_001222031.1 148272470 5174367 1463199..1464770 1 NC_009480.1 conserved membrane protein, putative ABC transporter permease component (YP_062296.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056499.1| ABC transporter associated permease [Propionibacterium acnes KPA171202]).; membrane protein, putative ABC transporter permease component 1464770 5174367 CMM_1290 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative ABC transporter permease component YP_001222031.1 1463199 D 443906 CDS YP_001222032.1 148272471 5174237 1464824..1465111 1 NC_009480.1 conserved hypothetical protein (YP_062295.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228314.1| hypothetical protein Krad06001616 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1465111 5174237 CMM_1291 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222032.1 1464824 D 443906 CDS YP_001222033.1 148272472 5175843 complement(1465136..1466452) 1 NC_009480.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1466452 pncB 5175843 pncB Clavibacter michiganensis subsp. michiganensis NCPPB 382 nicotinate phosphoribosyltransferase YP_001222033.1 1465136 R 443906 CDS YP_001222034.1 148272473 5173324 1466543..1468006 1 NC_009480.1 conserved hypothetical protein (ZP_00228361.1| COG3046: Uncharacterized protein related to deoxyribodipyrimidine photolyase [Kineococcus radiotolerans SRS30216]; NP_624520.1| conserved hypothetical protein SCJ1.33 [Streptomyces coelicolor A3(2)]). pfam04244, DPRP, Deoxyribodipyrimidine photolyase-related protein.; Function unclear; hypothetical protein 1468006 5173324 CMM_1293 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222034.1 1466543 D 443906 CDS YP_001222035.1 148272474 5174688 1468065..1468949 1 NC_009480.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1468949 murI 5174688 murI Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamate racemase YP_001222035.1 1468065 D 443906 CDS YP_001222036.1 148272475 5175360 1468958..1469695 1 NC_009480.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 1469695 rph 5175360 rph Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonuclease PH YP_001222036.1 1468958 D 443906 CDS YP_001222037.1 148272476 5172954 1469707..1470315 1 NC_009480.1 putative xanthosine triphosphate pyrophosphatase (YP_062291.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228325.1| COG0127: Xanthosine triphosphate pyrophosphatase [Kineococcus radiotolerans SRS30216]; NP_739010.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). , cd00515, HAM1, NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. TIGR00042: HAM1 protein; Function unclear; putative xanthosine triphosphate pyrophosphatase 1470315 5172954 CMM_1296 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative xanthosine triphosphate pyrophosphatase YP_001222037.1 1469707 D 443906 CDS YP_001222038.1 148272477 5174173 1470406..1471323 1 NC_009480.1 putative cobalt-zinc-cadmium efflux permease, CDF family (Cation efflux system protein)(YP_063177.1| cobalt-zinc-cadmium efflux permease [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630824.1| putative efflux protein [Streptomyces coelicolor A3(2)]). , pfam01545,Cation_efflux, Cation efflux family. Members of this family are integral membrane proteins, that are found to increase tolerance to divalent metal ions such as cadmium,zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells.; High confidence in function and specificity; cobalt-zinc-cadmium efflux permease,CDF family 1471323 czcD 5174173 czcD Clavibacter michiganensis subsp. michiganensis NCPPB 382 cobalt-zinc-cadmium efflux permease,CDF family YP_001222038.1 1470406 D 443906 CDS YP_001222039.1 148272478 5174745 complement(1471378..1472106) 1 NC_009480.1 conserved membrane protein (YP_062290.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789563.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_940604.1| Putative integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00597, DedA, DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; Function unclear; hypothetical protein 1472106 5174745 CMM_1298 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222039.1 1471378 R 443906 CDS YP_001222040.1 148272479 5174275 1472374..1473798 1 NC_009480.1 Region start changed from 1472365 to 1472374 (-9 bases); putative xylulose kinase 1473798 5174275 CMM_1299 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative xylulose kinase YP_001222040.1 1472374 D 443906 CDS YP_001222041.1 148272480 5174133 1473870..1475105 1 NC_009480.1 putative ATPase, type II/type IV pathway secretion protein (AAO44286.1| putative type II/type IV pathway secretion protein [Tropheryma whipplei str. Twist]; ZP_00228298.1| COG4962: Flp pilus assembly protein, ATPase CpaF [Kineococcus radiotolerans SRS30216]). pfam00437,GSPII_E, Type II/IV secretion system protein. This family contains both type II and type IV pathway secretion proteins from bacteria. VirB11 ATPase is a subunit of the Agrobacterium tumefaciens transfer DNA (T-DNA) transfer system, a type IV secretion pathway required for delivery of T-DNA and effector proteins to plant cells during infection.; Function unclear; putative ATPase, type II/type IV pathway secretion protein 1475105 5174133 CMM_1300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase, type II/type IV pathway secretion protein YP_001222041.1 1473870 D 443906 CDS YP_001222042.1 148272481 5174577 1475102..1475965 1 NC_009480.1 conserved membrane protein, putative pilus assembly protein (NP_789510.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_628691.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00482, GSPII_F, Bacterial type II secretion system protein F domain.; Function unclear; membrane protein, putative pilus assembly protein 1475965 5174577 CMM_1301 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative pilus assembly protein YP_001222042.1 1475102 D 443906 CDS YP_001222043.1 148272482 5175609 1475962..1476912 1 NC_009480.1 conserved membrane protein, putative pilus assembly protein (NP_789509.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00228300.1| COG2064: Flp pilus assembly protein TadC [Kineococcus radiotolerans SRS30216]). pfam00482, GSPII_F, Bacterial type II secretion system protein F domain.; Function unclear; membrane protein, putative pilus assembly protein 1476912 5175609 CMM_1302 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative pilus assembly protein YP_001222043.1 1475962 D 443906 CDS YP_001222044.1 148272483 5174449 1476963..1477157 1 NC_009480.1 conserved membrane protein (ZP_00228301.1| hypothetical protein Krad06001602 [Kineococcus radiotolerans SRS30216]; NP_789508.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly; hypothetical protein 1477157 5174449 CMM_1303 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222044.1 1476963 D 443906 CDS YP_001222045.1 148272484 5174717 1477157..1477534 1 NC_009480.1 conserved secreted protein (ZP_00228302.1| hypothetical protein Krad06001603 [Kineococcus radiotolerans SRS30216]; NP_789507.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly only weak similarity to: COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; hypothetical protein 1477534 5174717 CMM_1304 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222045.1 1477157 D 443906 CDS YP_001222046.1 148272485 5175735 1477509..1477964 1 NC_009480.1 conserved hypothetical protein (ZP_00228303.1| hypothetical protein Krad06001604 [Kineococcus radiotolerans SRS30216]; NP_789506.1| putative membrane/secreted protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly. only weak similarity to: COG4961, TadG, Flp pilus assembly protein TadG [Intracellular trafficking and secretion].; hypothetical protein 1477964 5175735 CMM_1305 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222046.1 1477509 D 443906 CDS YP_001222047.1 148272486 5174999 1477961..1478500 1 NC_009480.1 puataive secreted protein (NP_789505.1| putative membrane protein [Tropheryma whipplei TW08/27]). may be involved in pilus assembly.; Hypothetical protein; putative secreted protein 1478500 5174999 CMM_1306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222047.1 1477961 D 443906 CDS YP_001222048.1 148272487 5173718 complement(1478508..1479815) 1 NC_009480.1 putative MFS permease (CAE40411.1| probable transporter [Bordetella pertussis]; NP_787325.1| multidrug efflux protein [Tropheryma whipplei str. Twist]; ZP_00226080.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 1479815 5173718 CMM_1307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001222048.1 1478508 R 443906 CDS YP_001222049.1 148272488 5174630 1479891..1480994 1 NC_009480.1 Peptide chain release factor 2 (RF-2) (YP_062287.1| peptide chain release factor 2 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228305.1| COG1186: Protein chain release factor B [Kineococcus radiotolerans SRS30216]). Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity). pfam00472, RF-1,Peptidyl-tRNA hydrolase domain. This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. prfB: peptide chain release factor 2.; High confidence in function and specificity; peptide chain release factor RF-2 1480994 prfB 5174630 prfB Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptide chain release factor RF-2 YP_001222049.1 1479891 D 443906 CDS YP_001222050.1 148272489 5174531 1481070..1482737 1 NC_009480.1 putative ABC transporter, ATP-binding protein involved in cell division (NP_789501.1| cell division ATP-binding protein FtsE [Tropheryma whipplei TW08/27]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putative ABC transporter, ATP-binding protein involved in cell division 1482737 ftsE 5174531 ftsE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein involved in cell division YP_001222050.1 1481070 D 443906 CDS YP_001222051.1 148272490 5173885 1482734..1483651 1 NC_009480.1 putative ABC transporter, permease component,involved in cell division (YP_062285.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44297.1| cell division protein FtsX [Tropheryma whipplei str. Twist]). pfam02687, FtsX, Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins. ftsX: cell division ABC transporter pe; High confidence in function and specificity; putative ABC transporter, permease component,involved in cell division 1483651 ftsX 5173885 ftsX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, permease component,involved in cell division YP_001222051.1 1482734 D 443906 CDS YP_001222052.1 148272491 5174190 1483718..1484194 1 NC_009480.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1484194 smpB 5174190 smpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 SsrA-binding protein YP_001222052.1 1483718 D 443906 CDS YP_001222053.1 148272492 5175037 complement(1484812..1486623) 1 NC_009480.1 putative iron ABC transporter, permease component (NP_359235.1| ABC transporter membrane-spanning permease -unknown substrate [Streptococcus pneumoniae R6]; ZP_00313850.1| COG1178: ABC-type Fe3+ transport system,permease component [Clostridium thermocellum ATCC 27405]).; Specificity unclear; putative iron ABC transporter, permease component 1486623 5175037 CMM_1312 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron ABC transporter, permease component YP_001222053.1 1484812 R 443906 CDS YP_001222054.1 148272493 5175036 complement(1486626..1487654) 1 NC_009480.1 putative iron ABC transporter, ATPase component (NP_359236.1| ABC transporter ATP-binding protein -unknown substrate [Streptococcus pneumoniae R6]; ZP_00313849.1| COG3842: ABC-type spermidine/putrescine transport systems, ATPase components [Clostridium thermocellum ATCC 27405]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily; Specificity unclear; putative iron ABC transporter, ATPase component 1487654 5175036 CMM_1313 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron ABC transporter, ATPase component YP_001222054.1 1486626 R 443906 CDS YP_001222055.1 148272494 5174349 complement(1487654..1488736) 1 NC_009480.1 putative iron ABC transporter, substrate-binding protein (NP_359237.1| ABC transporter substrate-binding protein - unknown substrate [Streptococcus pneumoniae R6]; ZP_00313848.1| COG1840: ABC-type Fe3+ transport system, periplasmic component [Clostridium thermocellum ATCC 27405]).; Specificity unclear; putative iron ABC transporter, substrate-binding protein 1488736 5174349 CMM_1314 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron ABC transporter, substrate-binding protein YP_001222055.1 1487654 R 443906 CDS YP_001222056.1 148272495 5174277 1488976..1490478 1 NC_009480.1 putative MFS-type efflux protein (ZP_00228110.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_733510.1| putative transmembrane efflux protein. [Streptomyces coelicolor A3(2)]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS-type efflux protein 1490478 5174277 CMM_1315 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS-type efflux protein YP_001222056.1 1488976 D 443906 CDS YP_001222057.1 148272496 5175546 complement(1490510..1491322) 1 NC_009480.1 putative monophosphatase (ZP_00227046.1| COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monnophosphatase family [Kineococcus radiotolerans SRS30216]; NP_824226.1| putative monophosphatase [Streptomyces avermitilis MA-4680]). pfam00459, Inositol_P, Inositol monophosphatase family.; Specificity unclear; putative monophosphatase 1491322 5175546 CMM_1316 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monophosphatase YP_001222057.1 1490510 R 443906 CDS YP_001222058.1 148272497 5175074 complement(1491333..1492409) 1 NC_009480.1 putative GTPase (ZP_00227044.1| COG1162: Predicted GTPases [Kineococcus radiotolerans SRS30216]; CAF19467.1| putative GTPase [Corynebacterium glutamicum ATCC 13032]).; Function unclear; putative GTPase 1492409 5175074 CMM_1317 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative GTPase YP_001222058.1 1491333 R 443906 CDS YP_001222059.1 148272498 5175900 complement(1492406..1493869) 1 NC_009480.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1493869 aroA 5175900 aroA Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-phosphoshikimate 1-carboxyvinyltransferase YP_001222059.1 1492406 R 443906 CDS YP_001222060.1 148272499 5173043 1493934..1494758 1 NC_009480.1 RNA polymerase sigma-factor, ECF subfamily (Sigma-24) (NP_962258.1| SigH [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00227040.1| COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Kineococcus radiotolerans SRS30216]). ,pfam04542, Sigma70_r2, Sigma-70 region 2. , pfam04545,Sigma70_r4, Sigma-70, region 4.; Specificity unclear; ECF subfamily RNA polymerase sigma factor 1494758 sigH 5173043 sigH Clavibacter michiganensis subsp. michiganensis NCPPB 382 ECF subfamily RNA polymerase sigma factor YP_001222060.1 1493934 D 443906 CDS YP_001222061.1 148272500 5173920 1494755..1494997 1 NC_009480.1 putative anti-sigma factor involved in the regulation of oxidative stress, putative regulation of sigH (directly upstream) (NP_939084.1| Putative anti sigma factor [Corynebacterium diphtheriae NCTC13129]; NP_824213.1| putative anti-sigma factor [Streptomyces avermitilis MA-4680]). COG5662, Predicted transmembrane transcriptional regulator [Transcription]; Specificity unclear; putative anti-sigma factor 1494997 rsrA 5173920 rsrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anti-sigma factor YP_001222061.1 1494755 D 443906 CDS YP_001222062.1 148272501 5174859 1495033..1495473 1 NC_009480.1 putative acetyl transferase (AAP83142.1| putative acetyltransferase [Lysobacter enzymogenes]; ZP_00107049.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Nostoc punctiforme]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase; Function unclear; putative acetyl transferase 1495473 5174859 CMM_1321 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyl transferase YP_001222062.1 1495033 D 443906 CDS YP_001222063.1 148272502 5174369 complement(1495574..1499392) 1 NC_009480.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; alpha-ketoglutarate decarboxylase 1499392 kgd 5174369 kgd Clavibacter michiganensis subsp. michiganensis NCPPB 382 alpha-ketoglutarate decarboxylase YP_001222063.1 1495574 R 443906 CDS YP_001222064.1 148272503 5173727 1499573..1501012 1 NC_009480.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 1501012 guaB3 5173727 guaB3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 inosine 5-monophosphate dehydrogenase YP_001222064.1 1499573 D 443906 CDS YP_001222065.1 148272504 5173262 1501126..1502556 1 NC_009480.1 conserved membrane protein (ZP_00227019.1| COG1253: Hemolysins and related proteins containing CBS domains [Kineococcus radiotolerans SRS30216]; NP_828257.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function. pfam03471, CorC_HlyC, Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters.; Function unclear; hypothetical protein 1502556 5173262 CMM_1324 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222065.1 1501126 D 443906 CDS YP_001222066.1 148272505 5174576 1502549..1503592 1 NC_009480.1 conserved membrane protein (ZP_00227018.1| COG1253: Hemolysins and related proteins containing CBS domains [Kineococcus radiotolerans SRS30216]; NP_828256.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]). pfam01595, DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571, CBS, CBS domain. CBS domains are small intracellular modules of unknown function.; Function unclear; hypothetical protein 1503592 5174576 CMM_1325 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222066.1 1502549 D 443906 CDS YP_001222067.1 148272506 5174956 complement(1503662..1504741) 1 NC_009480.1 putative NADH-dependent flavin oxidoreductase (AAK73169.1| NADH-dependent flavin oxidoreductase [Brevibacterium sp. HCU]; NP_739487.1| putative NADH-dependent flavin oxidoreductase [Corynebacterium efficiens YS-314]). pfam00724, Oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase family.InterPro: NADH:flavin oxidoreductase/NADH oxidase; Function unclear; putative oxidoreductase 1504741 5174956 CMM_1326 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222067.1 1503662 R 443906 CDS YP_001222068.1 148272507 5175212 1504825..1505757 1 NC_009480.1 putative sugar kinase (BAA94841.1| hypothetical protein [Arthrobacter sp. Q36]). pfam01256, Carb_kinase,Carbohydrate kinase. InterPro: Uncharacterized protein family UPF0031; Function unclear; hypothetical protein 1505757 5175212 CMM_1327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222068.1 1504825 D 443906 CDS YP_001222069.1 148272508 5175759 complement(1505754..1506434) 1 NC_009480.1 conserved hypothetical protein (ZP_00227777.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_939578.1| Putative secreted protein [Corynebacterium diphtheriae NCTC 13129]).; Function unclear; hypothetical protein 1506434 5175759 CMM_1328 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222069.1 1505754 R 443906 CDS YP_001222070.1 148272509 5175763 1506642..1506959 1 NC_009480.1 conserved hypothetical protein (NP_737931.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00228490.1| COG0011: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam01910, DUF77, Domain of unknown function DUF77. Domain of unknown function.; Function unclear; hypothetical protein 1506959 5175763 CMM_1329 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222070.1 1506642 D 443906 CDS YP_001222071.1 148272510 5175203 1507035..1508315 1 NC_009480.1 putative MFS permease (NP_384591.1| PUTATIVE TRANSPORT TRANSMEMBRANE PROTEIN [Sinorhizobium meliloti 1021]; YP_046983.1| putative permease (MFS superfamily) [Acinetobacter sp. ADP1]). pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 1508315 5175203 CMM_1330 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001222071.1 1507035 D 443906 CDS YP_001222072.1 148272511 5174136 complement(1508355..1509011) 1 NC_009480.1 putative two-component system response regulator (ZP_00225674.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]). pfam00196, GerE, Bacterial regulatory proteins, luxR family. pfam00072, Response_reg, Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 1509011 5174136 CMM_1331 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001222072.1 1508355 R 443906 CDS YP_001222073.1 148272512 5173607 complement(1509039..1510271) 1 NC_009480.1 putative membrane protein (ZP_01131051.1| hypothetical protein A20C1_00590 [marine actinobacterium PHSC20C1]; AAT89627.1| hypothetical protein Lxx18970 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1510271 5173607 CMM_1332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222073.1 1509039 R 443906 CDS YP_001222074.1 148272513 5174164 complement(1510268..1511422) 1 NC_009480.1 putative two-component system sensor kinase (BAB98004.1| Two-component system, sensory transduction histidine kinases [Corynebacterium glutamicum ATCC 13032]; NP_696797.1| possible histidine kinase sensor of two component system [Bifidobacterium longum NCC2705]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-,and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 1511422 5174164 CMM_1333 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001222074.1 1510268 R 443906 CDS YP_001222075.1 148272514 5173823 complement(1511593..1512273) 1 NC_009480.1 putative two-component system response regulator (ZP_00225674.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]; NP_737890.1| putative transcription regulator [Corynebacterium efficiens YS-314]). pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system response regulator 1512273 5173823 CMM_1334 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001222075.1 1511593 R 443906 CDS YP_001222076.1 148272515 5173731 complement(1512393..1513562) 1 NC_009480.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine; homoserine O-acetyltransferase 1513562 metX 5173731 metX Clavibacter michiganensis subsp. michiganensis NCPPB 382 homoserine O-acetyltransferase YP_001222076.1 1512393 R 443906 CDS YP_001222077.1 148272516 5173800 complement(1513646..1515016) 1 NC_009480.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 1515016 metY 5173800 metY Clavibacter michiganensis subsp. michiganensis NCPPB 382 O-acetylhomoserine aminocarboxypropyltransferase YP_001222077.1 1513646 R 443906 CDS YP_001222078.1 148272517 5173225 1515152..1515949 1 NC_009480.1 putative oxidoreductase/short chain dehydrogenase (NP_630900.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]; NP_601406.1| putative short-chain dehydrogenase [Corynebacterium glutamicum ATCC 13032]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Function unclear; putative oxidoreductase 1515949 5173225 CMM_1337 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222078.1 1515152 D 443906 CDS YP_001222079.1 148272518 5175794 complement(1515988..1516662) 1 NC_009480.1 putative transcriptional regulator, TetR-family (AAK45993.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis CDC1551]; NP_627555.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1516662 5175794 CMM_1338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001222079.1 1515988 R 443906 CDS YP_001222080.1 148272519 5175778 1516782..1517852 1 NC_009480.1 putative transporter involved in metal resistance (ZP_00121878.1| COG0861: Membrane protein TerC, possibly involved in tellurium resistance [Bifidobacterium longum DJO10A]; NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]). , pfam03741,TerC, Integral membrane protein TerC family.; Function unclear; TerC family integral membrane export protein 1517852 5175778 CMM_1339 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TerC family integral membrane export protein YP_001222080.1 1516782 D 443906 CDS YP_001222081.1 148272520 5175459 1517849..1518670 1 NC_009480.1 putative serine/threonine protein phosphatase (NP_787218.1| protein phosphatase [Tropheryma whipplei str. Twist]; ZP_00024666.1| COG0631: Serine/threonine protein phosphatase [Ralstonia metallidurans]). pfam00481,PP2C, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.; Specificity unclear; putative serine/threonine protein phosphatase 1518670 5175459 CMM_1340 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine protein phosphatase YP_001222081.1 1517849 D 443906 CDS YP_001222082.1 148272521 5175377 1518748..1520217 1 NC_009480.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1520217 leuC 5175377 leuC Clavibacter michiganensis subsp. michiganensis NCPPB 382 isopropylmalate isomerase large subunit YP_001222082.1 1518748 D 443906 CDS YP_001222083.1 148272522 5175578 1520220..1520834 1 NC_009480.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 1520834 leuD 5175578 leuD Clavibacter michiganensis subsp. michiganensis NCPPB 382 isopropylmalate isomerase small subunit YP_001222083.1 1520220 D 443906 CDS YP_001222084.1 148272523 5175404 1520877..1522205 1 NC_009480.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1522205 murA 5175404 murA Clavibacter michiganensis subsp. michiganensis NCPPB 382 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_001222084.1 1520877 D 443906 CDS YP_001222085.1 148272524 5174328 1522329..1523066 1 NC_009480.1 putative sugar phosphate acyltransferase 1523066 5174328 CMM_1344 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar phosphate acyltransferase YP_001222085.1 1522329 D 443906 CDS YP_001222086.1 148272525 5175309 1523074..1524126 1 NC_009480.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1524126 gpsA 5175309 gpsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_001222086.1 1523074 D 443906 CDS YP_001222087.1 148272526 5174346 1524129..1525238 1 NC_009480.1 D-alanine--D-alanine ligase (D-alanylalanine synthetase) (D-Ala-D-Ala ligase) (NP_629695.1| D-alanine-D-alanine ligase [Streptomyces coelicolor A3(2)]; ZP_00059114.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Thermobifida fusca]). pfam01820, Dala_Dala_ligas, D-ala D-ala ligase. This family contains D-alanine--D-alanine ligase enzymes EC:6.3.2.4.; High confidence in function and specificity; D-alanine-D-alanine ligase 1525238 ddlC 5174346 ddlC Clavibacter michiganensis subsp. michiganensis NCPPB 382 D-alanine-D-alanine ligase YP_001222087.1 1524129 D 443906 CDS YP_001222088.1 148272527 5174921 1525341..1526258 1 NC_009480.1 putative glycosyl transferase (AAK64294.1| unknown [Brevibacterium flavum]; NP_737258.1| putative glycosyl transferase [Corynebacterium efficiens YS-314]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 1526258 5174921 CMM_1347 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001222088.1 1525341 D 443906 CDS YP_001222089.1 148272528 5175205 complement(1526215..1526727) 1 NC_009480.1 hypothetical protein (NP_789197.1| conserved hypothetical lipoprotein [Tropheryma whipplei TW08/27]; NP_627822.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1526727 5175205 CMM_1348 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222089.1 1526215 R 443906 CDS YP_001222090.1 148272529 5175162 1526752..1527837 1 NC_009480.1 thiamine-monophosphate kinase (Thiamine-phosphate kinase)(NP_629697.1| putative thiamine monphosphate kinase [Streptomyces coelicolor A3(2)]; ZP_00059104.1| COG0611: Thiamine monophosphate kinase [Thermobifida fusca]).; High confidence in function and specificity; thiamin-monophosphate kinase 1527837 thiL 5175162 thiL Clavibacter michiganensis subsp. michiganensis NCPPB 382 thiamin-monophosphate kinase YP_001222090.1 1526752 D 443906 CDS YP_001222091.1 148272530 5174120 complement(1527834..1528445) 1 NC_009480.1 putative DNA methylase (CAF20026.1| N6-adenine-specific methylase [Corynebacterium glutamicum ATCC 13032]; ZP_00228410.1| COG0742: N6-adenine-specific methylase [Kineococcus radiotolerans SRS30216]). pfam03602, Cons_hypoth95, Conserved hypothetical protein 95.; Specificity unclear; putative DNA methylase 1528445 5174120 CMM_1350 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA methylase YP_001222091.1 1527834 R 443906 CDS YP_001222092.1 148272531 5175111 1528715..1529674 1 NC_009480.1 putative regulatory protein, ATPase (NP_626353.1| putative regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00225463.1| COG0714: MoxR-like ATPases [Kineococcus radiotolerans SRS30216]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.; Function unclear; putative regulatory protein, ATPase 1529674 5175111 CMM_1351 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative regulatory protein, ATPase YP_001222092.1 1528715 D 443906 CDS YP_001222093.1 148272532 5174964 1529700..1531007 1 NC_009480.1 conserved memebrane protein (NP_626354.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00225464.1| COG1721: Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [Kineococcus radiotolerans SRS30216]). InterPro: Protein of unknown function DUF58 pfam01882, DUF58,Protein of unknown function DUF58.; Function unclear; hypothetical protein 1531007 5174964 CMM_1352 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222093.1 1529700 D 443906 CDS YP_001222094.1 148272533 5174909 1531004..1533547 1 NC_009480.1 putative membrane-bound protease (NP_626355.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00057749.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Thermobifida fusca]). pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine,and aspartate residues that form the catalytic triad in the structurally characterised transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologues of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.; Function unclear; putative membrane-bound protease 1533547 5174909 CMM_1353 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound protease YP_001222094.1 1531004 D 443906 CDS YP_001222095.1 148272534 5174898 1533544..1535727 1 NC_009480.1 ATP-dependent DNA helicase recG (ZP_00059102.1| COG1200: RecG-like helicase [Thermobifida fusca]; NP_629701.1| putative ATP-dependent DNA helicase [Streptomyces coelicolor A3(2)]). Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3 to 5 polarity. RecG unwind branched duplex DNA (Y-DNA) (By similarity). InterPro: DEAD/DEAH box helicase pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain. recG: ATP-dependent DNA helicase RecG; High confidence in function and specificity; ATP-dependent DNA helicase 1535727 recG 5174898 recG Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent DNA helicase YP_001222095.1 1533544 D 443906 CDS YP_001222096.1 148272535 5174177 1535754..1536245 1 NC_009480.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1536245 coaD 5174177 coaD Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphopantetheine adenylyltransferase YP_001222096.1 1535754 D 443906 CDS YP_001222097.1 148272536 5173162 1536265..1536837 1 NC_009480.1 conserved hypothetical protein (ZP_00228407.1| COG1399: Predicted metal-binding, possibly nucleic acid-binding protein [Kineococcus radiotolerans SRS30216]; NP_629705.1| hypothetical protein [Streptomyces coelicolor A3(2)]). pfam02620, DUF177, Uncharacterized ACR, COG1399.; hypothetical protein 1536837 5173162 CMM_1356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222097.1 1536265 D 443906 CDS YP_001222098.1 148272537 5174867 1536840..1537043 1 NC_009480.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1537043 rpmF 5174867 rpmF Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L32 YP_001222098.1 1536840 D 443906 CDS YP_001222099.1 148272538 5174840 1537069..1537785 1 NC_009480.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1537785 rnc 5174840 rnc Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonuclease III YP_001222099.1 1537069 D 443906 CDS YP_001222100.1 148272539 5174850 1537792..1538727 1 NC_009480.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 1538727 fpgA 5174850 fpgA Clavibacter michiganensis subsp. michiganensis NCPPB 382 formamidopyrimidine-DNA glycosylase YP_001222100.1 1537792 D 443906 CDS YP_001222101.1 148272540 5173659 complement(1538740..1539858) 1 NC_009480.1 putative acetyltransferase (NP_822401.1| hypothetical protein SAV1226 [Streptomyces avermitilis MA-4680]; NP_285343.1| hypothetical protein [Deinococcus radiodurans]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (duplicated). InterPro: GCN5-related N-acetyltransferase; Function unclear; putative acetyltransferase 1539858 5173659 CMM_1360 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222101.1 1538740 R 443906 CDS YP_001222102.1 148272541 5174834 1540015..1543770 1 NC_009480.1 putative chromosome segregation ATPase (NP_823834.1| putative chromosome segregation protein [Streptomyces avermitilis MA-4680]; Q9CBT5|SMC_MYCLE Chromosome partition protein smc). PLAYS AN IMPORTANT ROLE IN CHROMOSOME STRUCTURE AND PARTITIONING. ESSENTIAL FOR CHROMOSOME PARTITION (BY SIMILARITY). pfam02463, SMC_N,RecF/RecN/SMC N terminal domain. This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. pfam06470, SMC_hinge, SMC proteins Flexible Hinge Domain. pfam02483, SMC_C, SMC family, C-terminal domain. This Pfam family represents a conserved domain towards the C-terminus of the SMC family proteins.; High confidence in function and specificity; putative chromosome segregation ATPase 1543770 smcA 5174834 smcA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chromosome segregation ATPase YP_001222102.1 1540015 D 443906 CDS YP_001222103.1 148272542 5174339 1543791..1544666 1 NC_009480.1 Signal recognition particle component (SRP54)(NP_904493.1| signal recognition particle-docking protein FtsY [Porphyromonas gingivalis W83]; ZP_00098684.1| COG0552: Signal recognition particle GTPase [Desulfitobacterium hafniense]). Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). pfam02881, SRP54_N, SRP54-type protein, helical bundle domain. pfam00448, SRP54,SRP54-type protein, GTPase domain. This family includes relatives of the G-domain of the SRP54 family of proteins. InterPro: Cell division transporter substrate-binding protein FtsY; High confidence in function and specificity; Signal recognition particle component 1544666 ftsY 5174339 ftsY Clavibacter michiganensis subsp. michiganensis NCPPB 382 Signal recognition particle component YP_001222103.1 1543791 D 443906 CDS YP_001222104.1 148272543 5174196 1544729..1546300 1 NC_009480.1 Signal recognition particle protein (srp54) (AAL32278.1| signal recognition particle protein subunit [Arcanobacterium pyogenes]; NP_695507.1| signal recognition particle protein [Bifidobacterium longum NCC2705]; NP_823824.1| putative signal recognition particle [Streptomyces avermitilis MA-4680]). NECESSARY FOR EFFICIENT EXPORT OF EXTRA-CYTOPLASMIC PROTEINS. BINDS TO THE SIGNAL SEQUENCE WHEN IT EMERGES FROM THE RIBOSOMES (BY SIMILARITY). pfam00448, SRP54, SRP54-type protein,GTPase domain. This family includes relatives of the G-domain of the SRP54 family of proteins. pfam02978,SRP_SPB, Signal peptide binding domain. pfam02881,SRP54_N, SRP54-type protein, helical bundle domain.; High confidence in function and specificity; signal recognition particle protein 1546300 ffhA 5174196 ffhA Clavibacter michiganensis subsp. michiganensis NCPPB 382 signal recognition particle protein YP_001222104.1 1544729 D 443906 CDS YP_001222105.1 148272544 5173388 1546445..1546822 1 NC_009480.1 putative lyase (AAL78051.1| ORFC [Saccharopolyspora erythraea]; ZP_00051953.2| COG0346: Lactoylglutathione lyase and related lyases [Magnetospirillum magnetotacticum]; NP_821960.1| hypothetical protein SAV785 [Streptomyces avermitilis MA-4680]). pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; putative lyase 1546822 5173388 CMM_1364 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lyase YP_001222105.1 1546445 D 443906 CDS YP_001222106.1 148272545 5174767 complement(1546832..1548031) 1 NC_009480.1 putative membrane-associated serine protease,subfamily S1C (YP_061252.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292210.1| COG0265: Trypsin-like serine proteases, typically periplasmic,contain C-terminal PDZ domain [Thermobifida fusca]). contains two domains: N-terminal, pfam02674, Colicin_V,Colicin V production protein. C-terminal, pfam00089,Trypsin, Trypsin. InterPro: Serine proteases trypsin family.; Function unclear; membrane-associated serine protease 1548031 5174767 CMM_1365 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane-associated serine protease YP_001222106.1 1546832 R 443906 CDS YP_001222107.1 148272546 5174736 complement(1548045..1549196) 1 NC_009480.1 Region start changed from 1549235 to 1549196 (-39 bases); hypothetical protein 1549196 5174736 CMM_1366 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222107.1 1548045 R 443906 CDS YP_001222108.1 148272547 5174658 1549452..1549865 1 NC_009480.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1549865 rpsP 5174658 rpsP Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S16 YP_001222108.1 1549452 D 443906 CDS YP_001222109.1 148272548 5174312 1549869..1550105 1 NC_009480.1 putative RNA-binding protein (YP_062402.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198094.1| COG1837: Predicted RNA-binding protein (contains KH domain)[Kineococcus radiotolerans SRS30216]). pfam00013, KH, KH domain. KH motifs can bind RNA in vitro.; Function unclear; hypothetical protein 1550105 5174312 CMM_1368 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222109.1 1549869 D 443906 CDS YP_001222110.1 148272549 5174626 1550137..1550718 1 NC_009480.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1550718 rimM 5174626 rimM Clavibacter michiganensis subsp. michiganensis NCPPB 382 16S rRNA-processing protein RimM YP_001222110.1 1550137 D 443906 CDS YP_001222111.1 148272550 5173762 1550720..1551406 1 NC_009480.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1551406 trmD 5173762 trmD Clavibacter michiganensis subsp. michiganensis NCPPB 382 tRNA (guanine-N(1)-)-methyltransferase YP_001222111.1 1550720 D 443906 CDS YP_001222112.1 148272551 5175443 complement(1551426..1552193) 1 NC_009480.1 putative methionine aminopeptidase (Peptidase M) (YP_062397.1| methionine aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; AAN25516.1| methionine aminopeptidase [Bifidobacterium longum NCC2705]). Removes the amino-terminal methionine from nascent proteins. pfam00557, Peptidase_M24, metallopeptidase family M24.; High confidence in function and specificity; putative methionine aminopeptidase 1552193 mapA1 5175443 mapA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methionine aminopeptidase YP_001222112.1 1551426 R 443906 CDS YP_001222113.1 148272552 5174845 1552264..1552755 1 NC_009480.1 Hypothetical protein; hypothetical protein 1552755 5174845 CMM_1372 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222113.1 1552264 D 443906 CDS YP_001222114.1 148272553 5174240 1552926..1553270 1 NC_009480.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1553270 rplS 5174240 rplS Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L19 YP_001222114.1 1552926 D 443906 CDS YP_001222115.1 148272554 5175692 1553337..1554089 1 NC_009480.1 putative signal peptidase I (Leader peptidase I)(YP_062656.1| signal peptidase I [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225759.1| COG0681: Signal peptidase I [Kineococcus radiotolerans SRS30216]). pfam00461, Peptidase_S26, Signal peptidase I.; Function unclear; putative signal peptidase I 1554089 lepB 5175692 lepB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative signal peptidase I YP_001222115.1 1553337 D 443906 CDS YP_001222116.1 148272555 5173114 1554089..1554748 1 NC_009480.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1554748 rnhB 5173114 rnhB Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonuclease HII YP_001222116.1 1554089 D 443906 CDS YP_001222117.1 148272556 5173036 1554822..1555145 1 NC_009480.1 conserved hypothetical protein (YP_062394.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; CAA98339.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; CAF20372.1| putative CTP synthase (UTP-ammonia lyase) [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 1555145 5173036 CMM_1376 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222117.1 1554822 D 443906 CDS YP_001222118.1 148272557 5174178 1555257..1555613 1 NC_009480.1 conserved hypothetical protein, putative endonuclease (YP_062393.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629736.1| hypothetical protein [Streptomyces coelicolor A3(2)]; CAA98371.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02021, UPF0102, Uncharacterised protein family UPF0102. The function of this family is unknown.; hypothetical protein 1555613 5174178 CMM_1377 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222118.1 1555257 D 443906 CDS YP_001222119.1 148272558 5174174 1555613..1557169 1 NC_009480.1 putative ATP-dependant serine protease (NP_789248.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; YP_062392.1| competence protein M [Leifsonia xyli subsp. xyli str. CTCB07]). pfam05362,Lon_C, Lon protease (S16) C-terminal proteolytic domain. The Lon serine proteases must hydrolyse ATP to degrade protein substrates. pfam00004, AAA, ATPase family associated with various cellular activities (AAA). (pfam01078, Mg_chelatase, Magnesium chelatase, subunit ChlI. Magnesium-chelatase is a three-component enzyme that catalyses the insertion of Mg2+ into protoporphyrin IX.); Function unclear; putative ATP-dependant serine protease 1557169 5174174 CMM_1378 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependant serine protease YP_001222119.1 1555613 D 443906 CDS YP_001222120.1 148272559 5174122 1557364..1558659 1 NC_009480.1 putative DNA processing protein (YP_062391.1| DNA processing factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789249.1| putative DNA processing protein [Tropheryma whipplei TW08/27]). , pfam02481, SMF, SMF family. The SMF family (DNA processing chain A, dprA) are a group of bacterial proteins.; Function unclear; hypothetical protein 1558659 5174122 CMM_1379 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222120.1 1557364 D 443906 CDS YP_001222121.1 148272560 5174050 1558833..1559729 1 NC_009480.1 putative tyrosine recombinase (NP_961892.1| XerC [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_789250.1| putative DNA recombinase [Tropheryma whipplei TW08/27]). pfam02899, Phage_integr_N, Phage integrase, N-terminal SAM-like domain. pfam00589, Phage_integrase,Phage integrase family. Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment. The catalytic site residues in CRE recombinase are Arg-173, His-289, Arg-292 and Tyr-324.; Specificity unclear; integrase/recombinase 1559729 xerC 5174050 xerC Clavibacter michiganensis subsp. michiganensis NCPPB 382 integrase/recombinase YP_001222121.1 1558833 D 443906 CDS YP_001222122.1 148272561 5174006 complement(1559800..1560351) 1 NC_009480.1 putative metalloprotease, family M23B (NP_696656.1| narrowly conserved hypothetical protein in M23/M37 peptidase family [Bifidobacterium longum NCC2705]; NP_789252.1| hypothetical protein [Tropheryma whipplei TW08/27]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Function unclear; M23B family metallopeptidase 1560351 5174006 CMM_1381 Clavibacter michiganensis subsp. michiganensis NCPPB 382 M23B family metallopeptidase YP_001222122.1 1559800 R 443906 CDS YP_001222123.1 148272562 5173936 1560452..1561927 1 NC_009480.1 putative sugar MFS permease (YP_062390.1| sugar transporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198873.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. SP: Sugar transporter; Specificity unclear; putative sugar MFS permease 1561927 5173936 CMM_1382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar MFS permease YP_001222123.1 1560452 D 443906 CDS YP_001222124.1 148272563 5173737 1562166..1563113 1 NC_009480.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1563113 rpsB 5173737 rpsB Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S2 YP_001222124.1 1562166 D 443906 CDS YP_001222125.1 148272564 5175713 1563223..1564050 1 NC_009480.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1564050 tsf 5175713 tsf Clavibacter michiganensis subsp. michiganensis NCPPB 382 elongation factor Ts YP_001222125.1 1563223 D 443906 CDS YP_001222126.1 148272565 5175890 1564207..1564923 1 NC_009480.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1564923 pyrH 5175890 pyrH Clavibacter michiganensis subsp. michiganensis NCPPB 382 uridylate kinase YP_001222126.1 1564207 D 443906 CDS YP_001222127.1 148272566 5173857 1565037..1565594 1 NC_009480.1 frrA; Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1565594 frr 5173857 frr Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribosome recycling factor YP_001222127.1 1565037 D 443906 CDS YP_001222128.1 148272567 5173696 1565595..1566635 1 NC_009480.1 putative phosphatidate cytidylyltransferase (CDP-diacylglycerol synthase) (CTP:phosphatidate cytidylyltransferase) (NP_337459.1| phosphatidate cytidylyltransferase, putative [Mycobacterium tuberculosis CDC1551]; YP_062197.1| phosphatidate cytidylyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01148,CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases.; Specificity unclear; putative phosphatidate cytidylyltransferase 1566635 cdsA 5173696 cdsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatidate cytidylyltransferase YP_001222128.1 1565595 D 443906 CDS YP_001222129.1 148272568 5173205 1566646..1567191 1 NC_009480.1 conserved hypothetical protein (YP_062198.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789259.1| hypothetical protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1567191 5173205 CMM_1388 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222129.1 1566646 D 443906 CDS YP_001222130.1 148272569 5175295 1567295..1567999 1 NC_009480.1 conserved secreted protein, putative transglycosylase (YP_062199.1| secreted protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291803.1| COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Thermobifida fusca]). weak similarity to: pfam01464, SLT,Transglycosylase SLT domain.; Conserved hypothetical protein; hypothetical protein 1567999 5175295 CMM_1389 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222130.1 1567295 D 443906 CDS YP_001222131.1 148272570 5174841 1568070..1569800 1 NC_009480.1 Putative Na(+)/H(+) antiporter, CPA1 family (YP_061417.1| Na+/H+ antiporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00189223.3| COG0025: NhaP-type Na+/H+ and K+/H+ antiporters [Kineococcus radiotolerans SRS30216]). pfam00999, Na_H_Exchanger, Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. TIGRFAM (TIGR00831): Na+/H+ antiporter.; High confidence in function and specificity; CPA1 family Na+/H+ antiporter 1569800 5174841 CMM_1390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CPA1 family Na+/H+ antiporter YP_001222131.1 1568070 D 443906 CDS YP_001222132.1 148272571 5174366 1569836..1570132 1 NC_009480.1 putative ATP-/GTP-binding protein (YP_062200.1| ATP/GTP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293982.1| hypothetical protein Tfus02000184 [Thermobifida fusca]).; Conserved hypothetical protein; putative ATP-/GTP-binding protein 1570132 5174366 CMM_1391 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-/GTP-binding protein YP_001222132.1 1569836 D 443906 CDS YP_001222133.1 148272572 5173553 1570129..1570863 1 NC_009480.1 conserved hypothetical protein, putative hydrolase (YP_062201.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228488.1| COG2945: Predicted hydrolase of the alpha/beta superfamily [Kineococcus radiotolerans SRS30216]). weak similarity to: pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. gatB: glutamyl-tRNA(Gln) amidotransferas; Function unclear; hypothetical protein 1570863 5173553 CMM_1392 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222133.1 1570129 D 443906 CDS YP_001222134.1 148272573 5174931 complement(1570892..1571950) 1 NC_009480.1 conserved membrane protein, AI-E2 family (NP_789283.1| conserved hypothetical integral membrane protein [Tropheryma whipplei TW08/27]; NP_629892.1| putative membrane protein [Streptomyces coelicolor A3(2)]). , pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function.; Conserved hypothetical protein; AI-E2 family membrane protein 1571950 5174931 CMM_1393 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AI-E2 family membrane protein YP_001222134.1 1570892 R 443906 CDS YP_001222135.1 148272574 5173347 complement(1571980..1573755) 1 NC_009480.1 conserved hypothetical protein (YP_062203.1| large Ala/Glu-rich protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789284.1| putative low complexity hydrophilic protein [Tropheryma whipplei TW08/27]).; hypothetical protein 1573755 5173347 CMM_1394 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222135.1 1571980 R 443906 CDS YP_001222136.1 148272575 5173453 1574038..1575897 1 NC_009480.1 conserved membrane protein (YP_062204.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787545.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein 1575897 5173453 CMM_1395 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222136.1 1574038 D 443906 CDS YP_001222137.1 148272576 5174244 1575894..1576898 1 NC_009480.1 putative thioredoxin (YP_062205.1| thioredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055812.1| putative thioredoxin [Propionibacterium acnes KPA171202]). pfam00085, Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. cd00189, TPR, Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2) -[ASL]-X(4)-[PKE] is the consensus sequence.; Family membership; putative thioredoxin 1576898 5174244 CMM_1396 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001222137.1 1575894 D 443906 CDS YP_001222138.1 148272577 5174492 complement(1576974..1579553) 1 NC_009480.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 1579553 glgB 5174492 glgB Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycogen branching enzyme YP_001222138.1 1576974 R 443906 CDS YP_001222139.1 148272578 5175558 complement(1579559..1581697) 1 NC_009480.1 putative glycosidase (YP_062207.1| alpha-amylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228507.1| COG0366: Glycosidases [Kineococcus radiotolerans SRS30216]). , pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycosidase 1581697 5175558 CMM_1398 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosidase YP_001222139.1 1579559 R 443906 CDS YP_001222140.1 148272579 5173309 1582236..1584791 1 NC_009480.1 putative glucan phosphorylase (NP_733664.1| putative glycogen phosphorylase [Streptomyces coelicolor A3(2)]; ZP_00228508.1| COG0058: Glucan phosphorylase [Kineococcus radiotolerans SRS30216]). pfam00343,Phosphorylase, Carbohydrate phosphorylase. The members of this family catalyse the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch,glucan or maltodextrin.; Specificity unclear; putative glucan phosphorylase 1584791 glgP 5173309 glgP Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucan phosphorylase YP_001222140.1 1582236 D 443906 CDS YP_001222141.1 148272580 5175834 complement(1584831..1586138) 1 NC_009480.1 hypothetical secreted protein (ZP_00414486.1| hypothetical protein ArthDRAFT_0607 [Arthrobacter sp. FB24]).; hypothetical protein 1586138 5175834 CMM_1400 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222141.1 1584831 R 443906 CDS YP_001222142.1 148272582 5174498 complement(1586295..1588373) 1 NC_009480.1 putative glycosyl hydrolase (ZP_00228514.1| COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases [Kineococcus radiotolerans SRS30216]; YP_055821.1| putative glycogen debranching enzyme [Propionibacterium acnes KPA171202]). pfam02922,Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. InterPro: Glycoside hydrolase family 13; Specificity unclear; putative glycosyl hydrolase 1588373 glgX 5174498 glgX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl hydrolase YP_001222142.1 1586295 R 443906 CDS YP_001222143.1 148272581 5173004 1588372..1589577 1 NC_009480.1 putative cysteine desulfurase (NP_629622.1| putative pyridoxal-phosphate-dependent aminotransferase [Streptomyces coelicolor A3(2)]; YP_062359.1| cysteine desulfurase [Leifsonia xyli subsp. xyli str. CTCB07]). Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). pfam00266, Aminotran_5,Aminotransferase class-V. InterPro: Aminotransferase class-V; Specificity unclear; putative cysteine desulfurase 1589577 csdA 5173004 csdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cysteine desulfurase YP_001222143.1 1588372 D 443906 CDS YP_001222144.1 148272583 5173906 1589574..1590737 1 NC_009480.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1590737 mnmA 5173906 mnmA Clavibacter michiganensis subsp. michiganensis NCPPB 382 tRNA-specific 2-thiouridylase MnmA YP_001222144.1 1589574 D 443906 CDS YP_001222145.1 148272584 5174763 1590745..1593306 1 NC_009480.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1593306 ligA 5174763 ligA Clavibacter michiganensis subsp. michiganensis NCPPB 382 NAD-dependent DNA ligase LigA YP_001222145.1 1590745 D 443906 CDS YP_001222146.1 148272585 5174095 1593419..1594801 1 NC_009480.1 conserved secreted protein (YP_062355.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626621.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1594801 5174095 CMM_1405 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222146.1 1593419 D 443906 CDS YP_001222147.1 148272586 5173507 complement(1594813..1595268) 1 NC_009480.1 putative secreted protein (NP_716552.1| conserved hypothetical protein [Shewanella oneidensis MR-1]). pfam03724, META, Domain of unknown function (306). Small domain family found in proteins of of unknown function.; putative secreted protein 1595268 5173507 CMM_1406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222147.1 1594813 R 443906 CDS YP_001222148.1 148272587 5173000 1595316..1595684 1 NC_009480.1 putative glutamyl-tRNA(Gln) amidotransferase subunit C (Glu-ADT subunit C) (YP_062354.1| glutamyl-tRNA amidotransferase subunit C [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228527.1| COG0721: Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Kineococcus radiotolerans SRS30216]). pfam02686, Glu-tRNAGln, Glu-tRNAGln amidotransferase C subunit. This is a family of Glu-tRNAGln amidotransferase C subunits. The Glu-tRNA Gln amidotransferase enzyme itself is an important translational fidelity mechanism replacing incorrectly charged Glu-tRNAGln with the correct Gln-tRANGln via transmidation of the misacylated Glu-tRNAGln. This activity supplements the lack of glutaminyl-tRNA synthetase activity in gram-positive eubacterteria,cyanobacteria, Archaea, and organelles. InterPro: Glutamyl-tRNA(Gln) amidotransferase C subunit TIGRFam: gatC: glutamyl-tRNA(Gln) amidotransferase; High confidence in function and specificity; glutamyl-tRNA(Gln) amidotransferase subunit C 1595684 gatC 5173000 gatC Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamyl-tRNA(Gln) amidotransferase subunit C YP_001222148.1 1595316 D 443906 CDS YP_001222149.1 148272588 5175120 1595692..1597239 1 NC_009480.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1597239 gatA 5175120 gatA Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_001222149.1 1595692 D 443906 CDS YP_001222150.1 148272589 5175016 1597239..1598741 1 NC_009480.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1598741 gatB 5175016 gatB Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_001222150.1 1597239 D 443906 CDS YP_001222151.1 148272590 5175038 1598738..1600375 1 NC_009480.1 putative ABC transporter ATP-binding protein (CAF19765.1| ATPase component of ABC transporters with duplicated ATPase domains [Corynebacterium glutamicum ATCC 13032]; NP_630815.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter (2 times). InterPro: AAA ATPase superfamily.; Function unclear; putative ABC transporter ATP-binding protein 1600375 5175038 CMM_1410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter ATP-binding protein YP_001222151.1 1598738 D 443906 CDS YP_001222152.1 148272591 5175809 complement(1600400..1602049) 1 NC_009480.1 putative secreted protein (CAF19985.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]). Mtu_fam_11: Mycobacterium tuberculosis; putative secreted protein 1602049 5175809 CMM_1411 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222152.1 1600400 R 443906 CDS YP_001222153.1 148272592 5175665 1602196..1602912 1 NC_009480.1 conserved membrane protein (ZP_00226283.1| COG0586: Uncharacterized membrane-associated protein [Kineococcus radiotolerans SRS30216]; NP_737534.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam00597, DedA, DedA family. This family combines the DedA related proteins and YIAN/YGIK family. Members of this family are not functionally characterised. InterPro: DedA family TIGR00367: K+-dependent Na+/Ca+ exchanger; Function unclear; hypothetical protein 1602912 5175665 CMM_1412 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222153.1 1602196 D 443906 CDS YP_001222154.1 148272593 5175973 1603039..1603707 1 NC_009480.1 conserved hypothetical protein (YP_061421.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227520.1| hypothetical protein Krad06003909 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1603707 5175973 CMM_1413 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222154.1 1603039 D 443906 CDS YP_001222155.1 148272594 5175917 complement(1603756..1605444) 1 NC_009480.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1605444 5175917 CMM_1414 Clavibacter michiganensis subsp. michiganensis NCPPB 382 long-chain-fatty-acid--CoA ligase YP_001222155.1 1603756 R 443906 CDS YP_001222156.1 148272595 5174988 complement(1605541..1605987) 1 NC_009480.1 conserved hypothetical protein (NP_960888.1| hypothetical protein MAP1954c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_631754.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1605987 5174988 CMM_1415 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222156.1 1605541 R 443906 CDS YP_001222157.1 148272596 5175296 complement(1606061..1607509) 1 NC_009480.1 putative dehydrogenase (YP_062999.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961968.1| hypothetical protein MAP3034 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO).; Specificity unclear; putative dehydrogenase 1607509 5175296 CMM_1416 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydrogenase YP_001222157.1 1606061 R 443906 CDS YP_001222158.1 148272597 5173355 complement(1607519..1608517) 1 NC_009480.1 putative short-chain dehydrogenase (ZP_00228984.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; ZP_00107839.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Nostoc punctiforme]; CAB76332.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; short chain dehydrogenase 1608517 5173355 CMM_1417 Clavibacter michiganensis subsp. michiganensis NCPPB 382 short chain dehydrogenase YP_001222158.1 1607519 R 443906 CDS YP_001222159.1 148272598 5175302 complement(1608615..1610303) 1 NC_009480.1 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1610303 5175302 CMM_1418 Clavibacter michiganensis subsp. michiganensis NCPPB 382 long-chain-fatty-acid--CoA ligase YP_001222159.1 1608615 R 443906 CDS YP_001222160.1 148272599 5175560 complement(1610368..1611297) 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_336791.1| oxidoreductase, short-chain dehydrogenase/reductase family [Mycobacterium tuberculosis CDC1551]; NP_535663.1| dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 1611297 5175560 CMM_1419 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001222160.1 1610368 R 443906 CDS YP_001222161.1 148272600 5173446 1611781..1612998 1 NC_009480.1 putative acetylornithine deacetylase (EAA64290.1| hypothetical protein AN1583.2 [Aspergillus nidulans FGSC A4]; ZP_00128135.1| COG0624: Acetylornithine deacetylase/ Succinyl-diaminopimelate desuccinylase and related deacylases [Pseudomonas syringae pv. syringae B728a]).,pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; putative acetylornithine deacetylase 1612998 argE 5173446 argE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetylornithine deacetylase YP_001222161.1 1611781 D 443906 CDS YP_001222162.1 148272601 5174666 complement(1612995..1613486) 1 NC_009480.1 conserved hypothetical protein, putative phosphoesterase (NP_828681.1| hypothetical protein SAV7505 [Streptomyces avermitilis MA-4680]; NP_302694.1| conserved hypotehical protein [Mycobacterium leprae TN]). InterPro: Uncharacterized protein family UPF0025 TIGR00040: conserved hypothetical protein; Function unclear; putative phosphoesterase 1613486 5174666 CMM_1421 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphoesterase YP_001222162.1 1612995 R 443906 CDS YP_001222163.1 148272602 5174564 1613567..1614100 1 NC_009480.1 putative acetyltransferase (NP_102782.1| hypothetical protein mlr1123 [Mesorhizobium loti MAFF303099]; NP_422206.1| acetyltransferase, GNAT family [Caulobacter crescentus CB15]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. TIGR00729: ribonuclease HII; Function unclear; putative acetyltransferase 1614100 5174564 CMM_1422 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222163.1 1613567 D 443906 CDS YP_001222164.1 148272603 5174816 1614159..1614773 1 NC_009480.1 putative sulfite oxidase (NP_822473.1| hypothetical protein SAV1298 [Streptomyces avermitilis MA-4680]; ZP_00051501.1| COG2041: Sulfite oxidase and related enzymes [Magnetospirillum magnetotacticum]). pfam00174,Oxidored_molyb, Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases.; Function unclear; putative sulfite oxidase 1614773 5174816 CMM_1423 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sulfite oxidase YP_001222164.1 1614159 D 443906 CDS YP_001222165.1 148272604 5175253 1614770..1615516 1 NC_009480.1 Region start changed from 1614740 to 1614770 (-30 bases); putative oxidoreductase 1615516 5175253 CMM_1424 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222165.1 1614770 D 443906 CDS YP_001222166.1 148272605 5175113 1615581..1616114 1 NC_009480.1 conserved hypothetical protein (AAT89246.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. , CTCB07]; ZP_01090609.1| hypothetical protein DSM3645_12896 [Blastopirellula marina DSM 3645]); hypothetical protein 1616114 5175113 CMM_1425 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222166.1 1615581 D 443906 CDS YP_001222167.1 148272606 5175106 1616230..1617228 1 NC_009480.1 conserved hypothetical protein (ZP_00198062.1| COG3662: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; ZP_00274370.1| COG3662: Uncharacterized protein conserved in bacteria [Ralstonia metallidurans CH34]). menD: 2-succinyl-6-hydroxy-24-cyclohex; hypothetical protein 1617228 5175106 CMM_1426 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222167.1 1616230 D 443906 CDS YP_001222168.1 148272607 5174486 1617311..1618603 1 NC_009480.1 DNA polymerase IV (YP_062348.1| DNA polymerase IV [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225516.1| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair [Kineococcus radiotolerans SRS30216]). Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity). pfam00817, IMS, impB/mucB/samB family. These proteins are involved in UV protection. InterPro: UMUC family (DNA-repair).; High confidence in function and specificity; DNA polymerase IV 1618603 dinB 5174486 dinB Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase IV YP_001222168.1 1617311 D 443906 CDS YP_001222169.1 148272608 5175670 1618615..1619118 1 NC_009480.1 putative membrane protein (YP_063067.1| hypothetical protein Lxx23000 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1619118 5175670 CMM_1428 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222169.1 1618615 D 443906 CDS YP_001222170.1 148272609 5174957 complement(1619167..1620480) 1 NC_009480.1 UDP-glucose 6-dehydrogenase (UDP-Glc dehydrogenase) (ZP_00226352.1| COG1004: Predicted UDP-glucose 6-dehydrogenase [Kineococcus radiotolerans SRS30216]; NP_334746.1| UDP-glucose 6-dehydrogenase [Mycobacterium tuberculosis CDC1551]). pfam03721, UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain. pfam00984, UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase family, central domain. pfam03720,UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain. InterPro: UDP-glucose/GDP-mannose dehydrogenase family.; High confidence in function and specificity; UDP-glucose 6-dehydrogenase 1620480 udgA 5174957 udgA Clavibacter michiganensis subsp. michiganensis NCPPB 382 UDP-glucose 6-dehydrogenase YP_001222170.1 1619167 R 443906 CDS YP_001222171.1 148272610 5172960 complement(1620650..1622452) 1 NC_009480.1 Malto-oligosyltrehalose trehalohydrolase (4- alpha-D-{(1->4)-alpha- D-glucano}trehalose trehalohydrolase) (Q44316|TREZ_ARTSQ Malto-oligosyltrehalose trehalohydrolase (MTHase) 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) ; Q53238|TREZ_RHIS1 Malto-oligosyltrehalose trehalohydrolase (MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase)). , pfam02922,Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. , pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. , InterPro: Glycoside hydrolase family 13.; High confidence in function and specificity; maltooligosyl trehalose trehalohydrolase 1622452 treZ 5172960 treZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 maltooligosyl trehalose trehalohydrolase YP_001222171.1 1620650 R 443906 CDS YP_001222172.1 148272611 5175231 complement(1622449..1624800) 1 NC_009480.1 Maltooligosyl trehalose synthase ((14)-alpha-D-glucan 1-alpha- D-glucosylmutase) (Q44315|TREY_ARTSQ Maltooligosyl trehalose synthase ((1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase); AAB95368.1| maltooligosyl trehalose synthase [Brevibacterium helvolum]). Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide maltooligosyl trehalose (alpha-maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation.; High confidence in function and specificity; maltooligosyl trehalose synthase 1624800 treY 5175231 treY Clavibacter michiganensis subsp. michiganensis NCPPB 382 maltooligosyl trehalose synthase YP_001222172.1 1622449 R 443906 CDS YP_001222173.1 148272612 5175895 complement(1624797..1627001) 1 NC_009480.1 putative glucan debranching enzyme (BAA94842.1| glycogen debranching enzyme [Arthrobacter sp. Q36]; AAR83844.1| glycogen debranching enzyme [Brevibacterium helvolum]). pfam02922, Isoamylase_N, Isoamylase N-terminal domain. This domain is found in a range of enzymes that act on branched substrates - isoamylase, pullulanase and branching enzyme. pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; High confidence in function and specificity; putative glucan debranching enzyme 1627001 treX 5175895 treX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucan debranching enzyme YP_001222173.1 1624797 R 443906 CDS YP_001222174.1 148272613 5175878 1627212..1627544 1 NC_009480.1 conserved hypothetical protein (YP_062346.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_782141.1| conserved protein [Clostridium tetani E88]; NP_831863.1| hypothetical protein [Bacillus cereus ATCC 14579]).; Function unclear; hypothetical protein 1627544 5175878 CMM_1433 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222174.1 1627212 D 443906 CDS YP_001222175.1 148272614 5175883 1627819..1628481 1 NC_009480.1 putative ABC-type transporter, permease component (NP_737744.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00120538.2| COG4721: Predicted membrane protein [Bifidobacterium longum DJO10A]; YP_062345.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]).; Function unclear; putative ABC-type transporter, permease component 1628481 5175883 CMM_1434 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC-type transporter, permease component YP_001222175.1 1627819 D 443906 CDS YP_001222176.1 148272615 5175194 1628484..1630046 1 NC_009480.1 putative ABC transporter, ATP-binding protein (ZP_00120537.1| COG1122: ABC-type cobalt transport system,ATPase component [Bifidobacterium longum DJO10A]; YP_062344.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]). cd00267,ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain (duplicated). InterPro: AAA ATPase superfamily; Specificity unclear; putative ABC transporter, ATP-binding protein 1630046 5175194 CMM_1435 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001222176.1 1628484 D 443906 CDS YP_001222177.1 148272616 5173586 1630043..1630837 1 NC_009480.1 putative ABC transporter, permease component (YP_062343.1| ABC-type cobalt transport system [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600308.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]). pfam02361, CbiQ, Cobalt transport protein.; Specificity unclear; putative ABC transporter, permease component 1630837 5173586 CMM_1436 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, permease component YP_001222177.1 1630043 D 443906 CDS YP_001222178.1 148272617 5175013 1630827..1631375 1 NC_009480.1 conserved hypothetical protein (YP_062342.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737747.1| hypothetical protein [Corynebacterium efficiens YS-314]). pfam00485, PRK,Phosphoribulokinase / Uridine kinase family. InterPro: ATP/GTP-binding site motif A (P-loop); Function unclear; hypothetical protein 1631375 5175013 CMM_1437 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222178.1 1630827 D 443906 CDS YP_001222179.1 148272618 5174830 1631385..1631657 1 NC_009480.1 hypothetical protein (YP_062341.1| Hypothetical protein Lxx14200 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1631657 5174830 CMM_1438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222179.1 1631385 D 443906 CDS YP_001222180.1 148272619 5173916 complement(1631752..1632102) 1 NC_009480.1 conserved hypothetical protein (ZP_00228025.1| COG3824: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_857503.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]). pfam06262, DUF1025, Domain of unknown function (DUF1025). Family of bacterial protein with undetermined function.; hypothetical protein 1632102 5173916 CMM_1439 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222180.1 1631752 R 443906 CDS YP_001222181.1 148272620 5174406 complement(1632354..1632974) 1 NC_009480.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 1632974 ornA 5174406 ornA Clavibacter michiganensis subsp. michiganensis NCPPB 382 oligoribonuclease YP_001222181.1 1632354 R 443906 CDS YP_001222182.1 148272621 5175649 1633031..1633246 1 NC_009480.1 putative membrane protein (NP_789296.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; NP_629003.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 1633246 5175649 CMM_1441 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222182.1 1633031 D 443906 CDS YP_001222183.1 148272622 5174952 1633300..1633611 1 NC_009480.1 Region start changed from 1633243 to 1633300 (-57 bases); putative thioredoxin 1633611 5174952 CMM_1442 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001222183.1 1633300 D 443906 CDS YP_001222184.1 148272623 5175262 1633739..1634560 1 NC_009480.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1634560 nadE 5175262 nadE Clavibacter michiganensis subsp. michiganensis NCPPB 382 NAD synthetase YP_001222184.1 1633739 D 443906 CDS YP_001222185.1 148272624 5174760 complement(1634639..1635346) 1 NC_009480.1 hypothetical protein (YP_062230.1| hypothetical protein Lxx12850 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787532.1| unknown [Tropheryma whipplei str. Twist]).; hypothetical protein 1635346 5174760 CMM_1444 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222185.1 1634639 R 443906 CDS YP_001222186.1 148272625 5175199 complement(1635428..1635664) 1 NC_009480.1 hypothetical protein 1635664 5175199 CMM_1445 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222186.1 1635428 R 443906 CDS YP_001222187.1 148272626 5174695 1635835..1636362 1 NC_009480.1 putative peptide methionine sulfoxide reductase (Protein- methionine-S-oxide reductase) (ZP_00301868.1| COG0225: Peptide methionine sulfoxide reductase [Novosphingobium aromaticivorans DSM 12444]; Q9RTB6|MSRA_DEIRA Peptide methionine sulfoxide reductase msrA (Protein-methionine-S-oxide reductase) (Peptide Met(O)reductase)). pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine. msrA: peptide methionine sulfoxide redu; High confidence in function and specificity; putative peptide methionine sulfoxide reductase 1636362 msrA 5174695 msrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide methionine sulfoxide reductase YP_001222187.1 1635835 D 443906 CDS YP_001222188.1 148272627 5174051 1636462..1636692 1 NC_009480.1 hypothetical protein 1636692 5174051 CMM_1447 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222188.1 1636462 D 443906 CDS YP_001222189.1 148272628 5173091 1636758..1637201 1 NC_009480.1 hypothetical protein 1637201 5173091 CMM_1448 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222189.1 1636758 D 443906 CDS YP_001222190.1 148272629 5174912 1637198..1637761 1 NC_009480.1 putative transcriptional regulator, MarR-family (NP_627419.1| putative MarR-family transcriptional repressor [Streptomyces coelicolor A3(2)]; NP_824874.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 1637761 5174912 CMM_1449 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001222190.1 1637198 D 443906 CDS YP_001222191.1 148272630 5174943 1637758..1638231 1 NC_009480.1 putative secreted protein (YP_062227.1| hypothetical protein Lxx12820 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789301.1| putative secreted protein [Tropheryma whipplei TW08/27]).; putative secreted protein 1638231 5174943 CMM_1450 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222191.1 1637758 D 443906 CDS YP_001222192.1 148272631 5175136 1638295..1639977 1 NC_009480.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1639977 5175136 CMM_1451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter ATP-binding protein YP_001222192.1 1638295 D 443906 CDS YP_001222193.1 148272632 5174754 1639982..1640461 1 NC_009480.1 putative thioesterase (ZP_00227872.1| COG0824: Predicted thioesterase [Kineococcus radiotolerans SRS30216]; NP_789303.1| hypothetical protein [Tropheryma whipplei TW08/27]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes, principally thioesterases. InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site.; Function unclear; putative thioesterase 1640461 5174754 CMM_1452 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioesterase YP_001222193.1 1639982 D 443906 CDS YP_001222194.1 148272633 5173565 complement(1640482..1641387) 1 NC_009480.1 putative acyl-coenzyme A thioesterase II (YP_062222.1| acyl-CoA thioesterase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227900.1| COG1946: Acyl-CoA thioesterase [Kineococcus radiotolerans SRS30216]). pfam02551, Acyl_CoA_thio, Acyl-CoA thioesterase. This family represents the thioesterase II domain (duplicated). tesB: acyl-CoA thioesterase II; Specificity unclear; putative acyl-CoA thioesterase II 1641387 tesB 5173565 tesB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA thioesterase II YP_001222194.1 1640482 R 443906 CDS YP_001222195.1 148272634 5175484 1641471..1642166 1 NC_009480.1 conserved hypothetical protein (YP_062221.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826546.1| hypothetical protein SAV5369 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1642166 5175484 CMM_1454 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222195.1 1641471 D 443906 CDS YP_001222196.1 148272635 5173897 complement(1642194..1642589) 1 NC_009480.1 hemoglobin-like protein, truncated hemoglobin family (NP_826547.1| putative globin [Streptomyces avermitilis MA-4680]; ZP_00058748.1| COG2346: Truncated hemoglobins [Thermobifida fusca])., , pfam01152,Bac_globin, Bacterial-like globin. This family of heme binding proteins are found mainly in bacteria. However they can also be found in some protozoa and plants as well., COG2346, Truncated hemoglobins.; Function unclear; hemoglobin-like protein 1642589 glbO 5173897 glbO Clavibacter michiganensis subsp. michiganensis NCPPB 382 hemoglobin-like protein YP_001222196.1 1642194 R 443906 CDS YP_001222197.1 148272636 5173974 complement(1642589..1643908) 1 NC_009480.1 conserved membrane protein (YP_061871.1| small-conductance mechanosensitive channel [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625136.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_626892.1| putative membrane protein [Streptomyces coelicolor A3(2)])., , pfam00924, MS_channel,Mechanosensitive ion channel., COG0668, MscS, Small-conductance mechanosensitive channel.; Family membership; hypothetical protein 1643908 5173974 CMM_1456 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222197.1 1642589 R 443906 CDS YP_001222198.1 148272637 5174412 complement(1644071..1646614) 1 NC_009480.1 Aminopeptidase N (Lysyl aminopeptidase) (Alanine aminopeptidase) (YP_061876.1| aminopeptidase N [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225907.1| COG0308: Aminopeptidase N [Kineococcus radiotolerans SRS30216]). pfam01433, Peptidase_M1, Peptidase family M1. Members of this family are aminopeptidases. InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity; hypothetical protein 1646614 pepN 5174412 pepN Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222198.1 1644071 R 443906 CDS YP_001222199.1 148272638 5175131 1646766..1647392 1 NC_009480.1 conserved hypothetical protein (ZP_00225908.1| hypothetical protein Krad06004249 [Kineococcus radiotolerans SRS30216]; CAA16043.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). weak similarity to: COG3917, NahD, 2-hydroxychromene-2-carboxylate isomerase [Secondary metabolites biosynthesis,transport, and catabolism]; pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure.; hypothetical protein 1647392 5175131 CMM_1458 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222199.1 1646766 D 443906 CDS YP_001222200.1 148272639 5175232 1647509..1647997 1 NC_009480.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 1647997 rpiA 5175232 rpiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribose-5-phosphate isomerase B YP_001222200.1 1647509 D 443906 CDS YP_001222201.1 148272640 5173598 1648004..1648993 1 NC_009480.1 putative formamidopyrimidine-DNA glycosylase involved in DNA repair (YP_061878.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787524.1| putative DNA glycosylase [Tropheryma whipplei str. Twist]). pfam01149, Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. pfam06831, H2TH,Formamidopyrimidine-DNA glycosylase H2TH domain.; High confidence in function and specificity; putative formamidopyrimidine-DNA glycosylase involved in DNA repair 1648993 mutM 5173598 mutM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative formamidopyrimidine-DNA glycosylase involved in DNA repair YP_001222201.1 1648004 D 443906 CDS YP_001222202.1 148272641 5175515 complement(1649193..1649678) 1 NC_009480.1 putative stress induced DNA-binding protein (YP_061879.1| starvation- induced DNA-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44492.1| stress induced DNA-binding protein [Tropheryma whipplei str. Twist]). pfam00210, Ferritin, Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.; Specificity unclear; putative stress induced DNA-binding protein 1649678 dpsA 5175515 dpsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative stress induced DNA-binding protein YP_001222202.1 1649193 R 443906 CDS YP_001222203.1 148272642 5175475 complement(1649831..1655266) 1 NC_009480.1 Hypothetical protein; hypothetical protein 1655266 5175475 CMM_1462 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222203.1 1649831 R 443906 CDS YP_001222204.1 148272643 5174448 1655837..1657291 1 NC_009480.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1657291 tig 5174448 tig Clavibacter michiganensis subsp. michiganensis NCPPB 382 trigger factor YP_001222204.1 1655837 D 443906 CDS YP_001222205.1 148272644 5173340 1657490..1658077 1 NC_009480.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1658077 clpP 5173340 clpP Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent Clp protease proteolytic subunit YP_001222205.1 1657490 D 443906 CDS YP_001222206.1 148272645 5174483 1658114..1658794 1 NC_009480.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1658794 clpP2 5174483 clpP2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent Clp protease proteolytic subunit YP_001222206.1 1658114 D 443906 CDS YP_001222207.1 148272646 5173287 complement(1658859..1660001) 1 NC_009480.1 putative monooxygenase (ZP_00292953.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Thermobifida fusca]; NP_822383.1| putative monooxygenase [Streptomyces avermitilis MA-4680]). pfam00296, Bac_luciferase,Luciferase-like monooxygenase. InterPro: bacterial luciferase family protein; Function unclear; putative monooxygenase 1660001 5173287 CMM_1466 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001222207.1 1658859 R 443906 CDS YP_001222208.1 148272647 5175294 1660153..1661433 1 NC_009480.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1661433 clpX 5175294 clpX Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent protease ATP-binding subunit ClpX YP_001222208.1 1660153 D 443906 CDS YP_001222209.1 148272648 5173979 complement(1661515..1663578) 1 NC_009480.1 putative peptidyl-dipeptidase (Dipeptidyl carboxypeptidase) (AAM40709.1| peptidyl-dipeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00198809.2| COG0339: Zn-dependent oligopeptidases [Kineococcus radiotolerans SRS30216]). REMOVES DIPEPTIDES FROM THE C-TERMINI OF N-BLOCKED TRIPEPTIDES TETRAPEPTIDES AND LARGER PEPTIDES. pfam01432, Peptidase_M3, Peptidase family M3.; High confidence in function and specificity; putative peptidyl-dipeptidase 1663578 dcpA 5173979 dcpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidyl-dipeptidase YP_001222209.1 1661515 R 443906 CDS YP_001222210.1 148272649 5175658 1663618..1664421 1 NC_009480.1 putative methylase (NP_823056.1| putative methyltransferase-UbiE family [Streptomyces avermitilis MA-4680]; NP_335290.1| methyltransferase, UbiE/COQ5 family [Mycobacterium tuberculosis CDC1551]). InterPro: ubiE/COQ5 methyltransferase; Function unclear; putative methylase 1664421 5175658 CMM_1469 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylase YP_001222210.1 1663618 D 443906 CDS YP_001222211.1 148272650 5175898 complement(1664434..1664697) 1 NC_009480.1 hypothetical protein (YP_061805.1| hypothetical protein Lxx07900 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1664697 5175898 CMM_1470 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222211.1 1664434 R 443906 CDS YP_001222212.1 148272651 5175813 complement(1664697..1665149) 1 NC_009480.1 putative acetyltransferase, GNAT family (YP_061806.1| acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_107750.1|; Function unclear; GNAT family acetyltransferase 1665149 5175813 CMM_1471 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GNAT family acetyltransferase YP_001222212.1 1664697 R 443906 CDS YP_001222213.1 148272652 5174088 complement(1665146..1667791) 1 NC_009480.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1667791 valS 5174088 valS Clavibacter michiganensis subsp. michiganensis NCPPB 382 valyl-tRNA synthetase YP_001222213.1 1665146 R 443906 CDS YP_001222214.1 148272653 5173341 complement(1667927..1669867) 1 NC_009480.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP; phosphoenolpyruvate carboxykinase 1669867 pckA 5173341 pckA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoenolpyruvate carboxykinase YP_001222214.1 1667927 R 443906 CDS YP_001222215.1 148272654 5175535 1669979..1671406 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (ZP_00227904.1| COG3800: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00057955.1| COG1396: Predicted transcriptional regulators [Thermobifida fusca]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam06114, DUF955,Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function. InterPro: Helix-turn-helix motif.; Specificity unclear; Cro/CI family transcriptional regulator 1671406 5175535 CMM_1474 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001222215.1 1669979 D 443906 CDS YP_001222216.1 148272655 5174935 complement(1671425..1673089) 1 NC_009480.1 putative oligopeptide ABC transporter ATP-binding protein, two fused domains (NP_768244.1| ABC transporter ATP-binding protein [Bradyrhizobium japonicum]; ZP_00191786.2| COG1123: ATPase components of various ABC-type transport systems, contain duplicated ATPase [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative oligopeptide ABC transporter, ATP-binding protein 1673089 5174935 CMM_1475 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, ATP-binding protein YP_001222216.1 1671425 R 443906 CDS YP_001222217.1 148272656 5174400 complement(1673086..1673946) 1 NC_009480.1 putative oligopeptide ABC transporter, permease component (ZP_00228687.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_768243.1| ABC transporter permease protein [Bradyrhizobium japonicum]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.; Specificity unclear; putative oligopeptide ABC transporter, permease component 1673946 5174400 CMM_1476 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001222217.1 1673086 R 443906 CDS YP_001222218.1 148272657 5174082 complement(1673943..1675013) 1 NC_009480.1 putative oligopeptide ABC transporter, permease component (ZP_00228686.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Kineococcus radiotolerans SRS30216]; NP_641209.1| ABC transporter permease [Xanthomonas axonopodis pv. citri str. 306]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter, permease component 1675013 5174082 CMM_1477 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001222218.1 1673943 R 443906 CDS YP_001222219.1 148272658 5175915 complement(1675010..1676656) 1 NC_009480.1 putative oligopeptide ABC transporter, substrate-binding protein (NP_641208.1| ABC transporter oligopeptide binding protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00191783.2| COG0747: ABC-type dipeptide transport system, periplasmic component [Kineococcus radiotolerans SRS30216]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative oligopeptide ABC transporter, substrate-binding protein 1676656 5175915 CMM_1478 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, substrate-binding protein YP_001222219.1 1675010 R 443906 CDS YP_001222220.1 148272659 5173733 1676761..1677366 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00189647.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_518756.1| PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum GMI1000]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 1677366 5173733 CMM_1479 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001222220.1 1676761 D 443906 CDS YP_001222221.1 148272660 5175204 1677476..1678237 1 NC_009480.1 putative expansin (AAK16222.1| cellulase CelA [Clavibacter michiganensis subsp. sepedonicus]; XP_367645.1| hypothetical protein MG07556.4 [Magnaporthe grisea 70-15]; AAL24497.1| alpha-expansin [Oryza sativa]).; Function unclear; putative expansin 1678237 expA 5175204 expA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative expansin YP_001222221.1 1677476 D 443906 CDS YP_001222222.1 148272661 5172994 1678314..1679063 1 NC_009480.1 putative SAM-dependant methyltransferase (NP_962393.1| hypothetical protein MAP3459 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00276697.1| COG0500: SAM-dependent methyltransferases [Ralstonia metallidurans CH34]). InterPro: SAM (and some other nucleotide) binding motif; Specificity unclear; putative SAM-dependant methyltransferase 1679063 5172994 CMM_1481 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative SAM-dependant methyltransferase YP_001222222.1 1678314 D 443906 CDS YP_001222223.1 148272662 5174668 1679310..1682612 1 NC_009480.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 1682612 ileS 5174668 ileS Clavibacter michiganensis subsp. michiganensis NCPPB 382 isoleucyl-tRNA synthetase YP_001222223.1 1679310 D 443906 CDS YP_001222224.1 148272663 5175481 1682609..1684183 1 NC_009480.1 folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (YP_061811.1| folylpolyglutamate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787604.1| folylpolyglutamate synthase; dihydrofolate synthase [Tropheryma whipplei str. Twist]; NP_826629.1| putative folylpolyglutamate synthase [Streptomyces avermitilis MA-4680]). Conversion of folates to polyglutamate derivatives. pfam01225, Mur_ligase, Mur ligase family, catalytic domain. This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. pfam02875, Mur_ligase_C, Mur ligase family,glutamate ligase domain.; High confidence in function and specificity; hypothetical protein 1684183 folC 5175481 folC Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222224.1 1682609 D 443906 CDS YP_001222225.1 148272664 5173631 1684180..1684677 1 NC_009480.1 putative membrane protein (YP_061812.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226697.1| hypothetical protein Krad06002845 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1684677 5173631 CMM_1484 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222225.1 1684180 D 443906 CDS YP_001222226.1 148272665 5173809 1684687..1685106 1 NC_009480.1 putative nucleoside diphosphate kinase (NDP kinase) (Nucleoside-2-P kinase) (YP_061813.1| nucleoside diphosphate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198869.1| COG0105: Nucleoside diphosphate kinase [Kineococcus radiotolerans SRS30216]). smart00562,NDK, These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity. InterPro: Nucleoside diphosphate kinase; High confidence in function and specificity; hypothetical protein 1685106 ndkA 5173809 ndkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222226.1 1684687 D 443906 CDS YP_001222227.1 148272666 5174380 complement(1685168..1685776) 1 NC_009480.1 conserved membrane protein (AAS20061.1| conserved hypothetical protein [Arthrobacter aurescens]; ZP_00227045.1| COG4243: Predicted membrane protein [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 1685776 5174380 CMM_1486 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222227.1 1685168 R 443906 CDS YP_001222228.1 148272667 5174570 1686082..1689102 1 NC_009480.1 putative ribonuclease (YP_061815.1| ribonuclease G [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292466.1| COG1530: Ribonucleases G and E [Thermobifida fusca]). pfam00575, S1, S1 RNA binding domain. The S1 domain occurs in a wide range of RNA associated proteins. RNaseEG: ribonuclease Rne/Rng family; Function unclear; putative ribonuclease 1689102 5174570 CMM_1487 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ribonuclease YP_001222228.1 1686082 D 443906 CDS YP_001222229.1 148272668 5175975 complement(1689191..1689469) 1 NC_009480.1 conserved hypothetical protein (YP_061816.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293669.1| hypothetical protein Tfus02001029 [Thermobifida fusca]).; hypothetical protein 1689469 5175975 CMM_1488 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222229.1 1689191 R 443906 CDS YP_001222230.1 148272669 5174828 1689759..1690067 1 NC_009480.1 50S ribosomal protein L21 (YP_061817.1| 50S ribosomal protein L21 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB03777.1| PROBABLE 50S RIBOSOMAL PROTEIN L21 RPLU [Mycobacterium tuberculosis H37Rv]; NP_940119.1| 50S ribosomal protein L21 [Corynebacterium diphtheriae NCTC 13129]). This protein binds to 23S ribosomal RNA in the presence of protein L20. pfam00829, Ribosomal_L21p,Ribosomal prokaryotic L21 protein.; High confidence in function and specificity; 50S ribosomal protein L21 1690067 rplU 5174828 rplU Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L21 YP_001222230.1 1689759 D 443906 CDS YP_001222231.1 148272670 5173819 1690092..1690346 1 NC_009480.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1690346 rpmA 5173819 rpmA Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L27 YP_001222231.1 1690092 D 443906 CDS YP_001222232.1 148272671 5175920 1690466..1692004 1 NC_009480.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1692004 obgE 5175920 obgE Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTPase ObgE YP_001222232.1 1690466 D 443906 CDS YP_001222233.1 148272672 5175636 1692008..1692787 1 NC_009480.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1692787 proB 5175636 proB Clavibacter michiganensis subsp. michiganensis NCPPB 382 gamma-glutamyl kinase YP_001222233.1 1692008 D 443906 CDS YP_001222234.1 148272673 5175829 1692835..1694133 1 NC_009480.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1694133 proA 5175829 proA Clavibacter michiganensis subsp. michiganensis NCPPB 382 gamma-glutamyl phosphate reductase YP_001222234.1 1692835 D 443906 CDS YP_001222235.1 148272674 5175760 1694234..1694449 1 NC_009480.1 hypothetical membrane protein (YP_061822.1| hypothetical protein Lxx08090 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1694449 5175760 CMM_1494 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222235.1 1694234 D 443906 CDS YP_001222236.1 148272675 5175208 1694467..1695069 1 NC_009480.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1695069 nadD 5175208 nadD Clavibacter michiganensis subsp. michiganensis NCPPB 382 nicotinic acid mononucleotide adenylyltransferase YP_001222236.1 1694467 D 443906 CDS YP_001222237.1 148272676 5173714 1695066..1696592 1 NC_009480.1 conserved hypothetical protein (YP_061824.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 1696592 5173714 CMM_1496 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222237.1 1695066 D 443906 CDS YP_001222238.1 148272677 5175310 1696632..1697009 1 NC_009480.1 conserved hypothetical protein (YP_061825.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00197999.1| COG0799: Uncharacterized homolog of plant Iojap protein [Kineococcus radiotolerans SRS30216]). pfam02410, DUF143, Domain of unknown function DUF143. This domain has no known function nor do any of the proteins that possess it.; Function unclear; hypothetical protein 1697009 5175310 CMM_1497 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222238.1 1696632 D 443906 CDS YP_001222239.1 148272678 5174584 1697041..1697457 1 NC_009480.1 conserved hypothetical protein (NP_952619.1| conserved hypothetical protein [Geobacter sulfurreducens PCA]; NP_282311.1| hypothetical protein Cj1164c [Campylobacter jejuni subsp. jejuni NCTC 11168]).; Function unclear; hypothetical protein 1697457 5174584 CMM_1498 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222239.1 1697041 D 443906 CDS YP_001222240.1 148272679 5174478 complement(1697691..1698695) 1 NC_009480.1 hypothetical protein (only weak similarities to: NP_980009.1| conserved hypothetical protein [Bacillus cereus ATCC 10987]).; hypothetical protein 1698695 5174478 CMM_1499 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222240.1 1697691 R 443906 CDS YP_001222241.1 148272680 5174927 1698747..1699070 1 NC_009480.1 hypothetical protein 1699070 5174927 CMM_1500 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222241.1 1698747 D 443906 CDS YP_001222242.1 148272681 5175022 1699112..1700116 1 NC_009480.1 putative esterase (YP_061243.1| secreted hydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_631558.1| putative secreted hydrolase [Streptomyces coelicolor A3(2)]). cd00229, SEST, Streptomyces scabies esterase is a causal agent of the potato scab disease. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases. InterPro: GDSL lipolytic enzyme TIGR00365: glutaredoxin-related protein; Function unclear; putative esterase 1700116 5175022 CMM_1501 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001222242.1 1699112 D 443906 CDS YP_001222243.1 148272682 5174162 1700253..1701041 1 NC_009480.1 putative transcriptional regulator, DeoR family (YP_061707.1| transcriptional regulator, DeoR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738434.1| putative deoR-family transcriptional regulator [Corynebacterium efficiens YS-314]). pfam00455, DeoR,Bacterial regulatory proteins, deoR family.; Hypothetical protein; DeoR family transcriptional regulator 1701041 5174162 CMM_1502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DeoR family transcriptional regulator YP_001222243.1 1700253 D 443906 CDS YP_001222244.1 148272683 5175909 1701038..1702009 1 NC_009480.1 putative 1-phosphofructokinase (YP_061708.1| 1-phosphofructokinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738438.1| putative 1-phosphofructokinase [Corynebacterium efficiens YS-314]). pfam00294, PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases. InterPro: PfkB family of carbohydrate kinases; Specificity unclear; putative 1-phosphofructokinase 1702009 fruK 5175909 fruK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 1-phosphofructokinase YP_001222244.1 1701038 D 443906 CDS YP_001222245.1 148272684 5173786 1702032..1704089 1 NC_009480.1 phosphoenolpyruvate-dependent fructose phosphotransferase system, EIIA, EIIB, EIIC (YP_054858.1| phosphotransferase system [Propionibacterium acnes KPA171202]; YP_061709.1| PTS system, fructose-specific permease, transmembrane protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. , pfam02379, PTS_IIB_fruc, PTS system,Fructose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The sugar-specific permease of the PTS consists of three domains (IIA, IIB and IIC). IIB is is phosphorylated by phospho-IIA, before the phosphoryl group is transferred to the sugar substrate. , pfam02378, PTS_EIIC,Phosphotransferase system, EIIC. , InterPro: Phosphotransferase system EIIC fruA: PTS system IIA component fructo; High confidence in function and specificity; phosphoenolpyruvate-dependent fructose phosphotransferase system, EIIA, EIIB, EIIC 1704089 fruA 5173786 fruA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoenolpyruvate-dependent fructose phosphotransferase system, EIIA, EIIB, EIIC YP_001222245.1 1702032 D 443906 CDS YP_001222246.1 148272685 5173729 1704145..1704417 1 NC_009480.1 phosphotransferase system, phosphocarrier protein HPr (ZP_00226194.1| COG1925: Phosphotransferase system,HPr-related proteins [Kineococcus radiotolerans SRS30216]; YP_055065.1| phosphocarrier protein HPr [Propionibacterium acnes KPA171202]). pfam00381, PTS-HPr,PTS HPr component phosphorylation site.; High confidence in function and specificity; phosphotransferase system, phosphocarrier protein HPr 1704417 fruB 5173729 fruB Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphotransferase system, phosphocarrier protein HPr YP_001222246.1 1704145 D 443906 CDS YP_001222247.1 148272686 5173829 complement(1704492..1706039) 1 NC_009480.1 putative short-chain dehydrogenase/oxidoreductase (NP_828433.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; NP_640936.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase 1706039 5173829 CMM_1506 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain dehydrogenase/oxidoreductase YP_001222247.1 1704492 R 443906 CDS YP_001222248.1 148272687 5175726 complement(1706121..1706396) 1 NC_009480.1 hypothetical protein 1706396 5175726 CMM_1506A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222248.1 1706121 R 443906 CDS YP_001222249.1 148272688 5175965 1706484..1709024 1 NC_009480.1 putative ATP-dependent helicase (NP_822750.1| putative ATP-dependent helicase [Streptomyces avermitilis MA-4680]; ZP_00293629.1| COG4581: Superfamily II RNA helicase [Thermobifida fusca]). pfam00270, DEAD, DEAD/DEAH box helicase. Members of this family include the DEAD and DEAH box helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Specificity unclear; putative ATP-dependent helicase 1709024 5175965 CMM_1507 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent helicase YP_001222249.1 1706484 D 443906 CDS YP_001222250.1 148272689 5175924 1709021..1709950 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_624645.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; CAA17300.1| Possible oxidoreductase [Mycobacterium tuberculosis H37Rv]). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 1709950 5175924 CMM_1508 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001222250.1 1709021 D 443906 CDS YP_001222251.1 148272690 5175268 complement(1709966..1711084) 1 NC_009480.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1711084 hisC1 5175268 hisC1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 histidinol-phosphate aminotransferase YP_001222251.1 1709966 R 443906 CDS YP_001222252.1 148272691 5173480 1711169..1712074 1 NC_009480.1 putative hydrolase (ZP_00108734.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Nostoc punctiforme]; NP_295075.1| dihydrolipoamide acetyltransferase-related protein [Deinococcus radiodurans R1]). pfam00561, Abhydrolase_1,alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. InterPro: Alpha/beta hydrolase fold hupD: hydrogenase expression/formation; Function unclear; putative hydrolase 1712074 5173480 CMM_1510 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001222252.1 1711169 D 443906 CDS YP_001222253.1 148272692 5175966 1712142..1712876 1 NC_009480.1 putative hydrolase/acyltransferase (ZP_00227961.1| COG1075: Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [Kineococcus radiotolerans SRS30216]; AAN48022.1| alpha/beta hydrolase fold [Leptospira interrogans serovar lai str. 56601]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. TIGR00253: conserved hypothetical prote; Function unclear; putative hydrolase/acyltransferase 1712876 5175966 CMM_1511 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001222253.1 1712142 D 443906 CDS YP_001222254.1 148272693 5175447 1712908..1714353 1 NC_009480.1 putative efflux MFS permease (YP_061828.1| transmembrane efflux pump [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627842.1| putative transmembrane efflux protein [Streptomyces coelicolor A3(2)]). efflux_EmrB: drug resistance transport; Specificity unclear; putative efflux MFS permease 1714353 5175447 CMM_1512 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative efflux MFS permease YP_001222254.1 1712908 D 443906 CDS YP_001222255.1 148272694 5175291 complement(1714350..1715327) 1 NC_009480.1 putative Zn-dependant oxidoreductase (NP_628012.1| putative quinone oxidoreductase [Streptomyces coelicolor A3(2)]; XP_468289.1| putative quinone oxidoreductase [Oryza sativa (japonica cultivar-group)]). pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily; Function unclear; putative Zn-dependant oxidoreductase 1715327 5175291 CMM_1513 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant oxidoreductase YP_001222255.1 1714350 R 443906 CDS YP_001222256.1 148272695 5175882 1715482..1716048 1 NC_009480.1 conserved hypothetical protein (YP_061830.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227945.1| COG2353: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam04264, YceI, YceI like family. E. coli YceI is a base-induced periplasmic protein. Its function has not yet been characterised.; Function unclear; hypothetical protein 1716048 5175882 CMM_1514 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222256.1 1715482 D 443906 CDS YP_001222257.1 148272696 5175000 complement(1716185..1717144) 1 NC_009480.1 putative hydrolase/acyltransferase (NP_661840.1| hydrolase, alpha/beta hydrolase fold family [Chlorobium tepidum TLS]; NP_821687.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase/acyltransferase 1717144 5175000 CMM_1515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001222257.1 1716185 R 443906 CDS YP_001222258.1 148272697 5175790 complement(1717308..1718240) 1 NC_009480.1 putative hydrolase/acyltransferase (ZP_00283301.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia fungorum LB400]; NP_822882.1| putative 3-oxoadipate enol-lactone hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase/acyltransferase 1718240 5175790 CMM_1516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001222258.1 1717308 R 443906 CDS YP_001222259.1 148272698 5174622 complement(1718237..1719283) 1 NC_009480.1 conserved membrane protein (YP_062173.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789315.1| putative integral membrane protein. [Tropheryma whipplei TW08/27]). TIGR00040: conserved hypothetical prot; Conserved hypothetical protein; hypothetical protein 1719283 5174622 CMM_1517 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222259.1 1718237 R 443906 CDS YP_001222260.1 148272699 5174737 complement(1719355..1722777) 1 NC_009480.1 DNA polymerase III alpha subunit (ZP_00225627.1| COG0587: DNA polymerase III, alpha subunit [Kineococcus radiotolerans SRS30216]; NP_827731.1| putative DNA polymerase III alpha subunit [Streptomyces avermitilis MA-4680]). DNA POLYMERASE III IS A COMPLEX MULTICHAIN ENZYME RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA. THIS DNA POLYMERASE ALSO EXHIBITS 3 TO 5 EXONUCLEASE ACTIVITY. THE ALPHA CHAIN IS THE DNA POLYMERASE. polc: DNA polymerase III alpha subuni; High confidence in function and specificity; DNA polymerase III, alpha chain 1722777 dnaE1 5174737 dnaE1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III, alpha chain YP_001222260.1 1719355 R 443906 CDS YP_001222261.1 148272700 5175517 1722892..1724259 1 NC_009480.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1724259 zwfA1 5175517 zwfA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glucose-6-phosphate 1-dehydrogenase YP_001222261.1 1722892 D 443906 CDS YP_001222262.1 148272701 5174391 1724367..1725110 1 NC_009480.1 putative carboxymethylenebutenolidase (EC 3.1.1.45) (Dienelactone hydrolase) (NP_216570.1| hypothetical protein Rv2054 [Mycobacterium tuberculosis H37Rv]; NP_531327.1| carboxymethylenebutenolidase [Agrobacterium tumefaciens str. C58 (U. Washington)] ). pfam01738, DLH,Dienelactone hydrolase family. InterPro: Dienelactone hydrolase.; Function unclear; putative carboxymethylenebutenolidase 1725110 5174391 CMM_1520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxymethylenebutenolidase YP_001222262.1 1724367 D 443906 CDS YP_001222263.1 148272702 5175230 1725174..1726481 1 NC_009480.1 putative transcriptional regulator, LytR family (YP_061827.1| transcriptional regulator, LytR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787856.1| transcriptional regulator [Tropheryma whipplei str. Twist]). pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.; Specificity unclear; LytR family transcriptional regulator 1726481 5175230 CMM_1521 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LytR family transcriptional regulator YP_001222263.1 1725174 D 443906 CDS YP_001222264.1 148272703 5173841 complement(1726516..1727436) 1 NC_009480.1 putative transcriptional regulator, LysR family (NP_534506.1| transcriptional regulator, LysR family [Agrobacterium tumefaciens str. C58]; YP_050354.1| LysR-family transcriptional regulator [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; LysR family transcriptional regulator 1727436 5173841 CMM_1522 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001222264.1 1726516 R 443906 CDS YP_001222265.1 148272704 5175040 1727505..1728032 1 NC_009480.1 putative acetyltransferase (YP_048512.1| putative acetyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00217564.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Burkholderia cepacia R18194]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1728032 5175040 CMM_1523 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222265.1 1727505 D 443906 CDS YP_001222266.1 148272705 5175343 complement(1728051..1728749) 1 NC_009480.1 putative nicotinamide mononucleotide transporter,PnuC family (CAF18632.1| mononucleotide transporter [Corynebacterium glutamicum ATCC 13032]; YP_056127.1| nicotinamide mononucleotide transporter [Propionibacterium acnes KPA171202]). pfam04973, NMN_transporter,Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.; Specificity unclear; nicotinamide mononucleotide transporter 1728749 5175343 CMM_1524 Clavibacter michiganensis subsp. michiganensis NCPPB 382 nicotinamide mononucleotide transporter YP_001222266.1 1728051 R 443906 CDS YP_001222267.1 148272706 5174180 complement(1728886..1729209) 1 NC_009480.1 hypothetical protein 1729209 5174180 CMM_1525 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222267.1 1728886 R 443906 CDS YP_001222268.1 148272707 5175255 1729463..1730332 1 NC_009480.1 putative oxidoreductase (NP_301411.1| putative oxidoreductase [Mycobacterium leprae TN]; ZP_00198753.2| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Function unclear; putative oxidoreductase 1730332 5175255 CMM_1526 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222268.1 1729463 D 443906 CDS YP_001222269.1 148272708 5174919 complement(1730403..1731542) 1 NC_009480.1 conserved hypothetical protein (YP_062174.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227742.1| COG4850: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; CAF20598.1| ATPase component of ABC transporters with duplicated ATPase domains [Corynebacterium glutamicum ATCC 13032]).; Function unclear; hypothetical protein 1731542 5174919 CMM_1527 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222269.1 1730403 R 443906 CDS YP_001222270.1 148272709 5175245 complement(1731539..1732270) 1 NC_009480.1 conserved hypothetical protein (ZP_00189333.2| COG2135: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_629361.1| conserved hypothetical protein SC7E4.11 [Streptomyces coelicolor A3(2)]). pfam02586, DUF159, Uncharacterised ACR, COG2135.; hypothetical protein 1732270 5175245 CMM_1528 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222270.1 1731539 R 443906 CDS YP_001222271.1 148272710 5175258 1732461..1733366 1 NC_009480.1 putative proline/glycine/betaine/choline ABC transporter, ATP-binding protein (AAP55490.1| PROV-like protein [Leifsonia xyli subsp. xyli]; NP_938494.1| choline transport system ATP-binding protein [Corynebacterium diphtheriae NCTC 13129]). PROBABLY INVOLVED IN OSMOPROTECTION. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter, ATP-binding protein 1733366 proV 5175258 proV Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proline/glycine/betaine/choline ABC transporter, ATP-binding protein YP_001222271.1 1732461 D 443906 CDS YP_001222272.1 148272711 5174153 1733363..1734064 1 NC_009480.1 putative proline/glycine/betaine/choline ABC transporter, permease component (YP_062177.1| ABC-type glycine betaine transport, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055115.1| ABC transporter-associated permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter, permease component 1734064 proW 5174153 proW Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proline/glycine/betaine/choline ABC transporter, permease component YP_001222272.1 1733363 D 443906 CDS YP_001222273.1 148272712 5174301 1734061..1734786 1 NC_009480.1 putative proline/glycine/betaine/choline ABC transporter, permease component (YP_062178.1| ABC-type glycine betaine transport, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055114.1| ABC transporter-associated permease [Propionibacterium acnes KPA171202]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter, permease component 1734786 proZ 5174301 proZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proline/glycine/betaine/choline ABC transporter, permease component YP_001222273.1 1734061 D 443906 CDS YP_001222274.1 148272713 5174057 1734800..1735729 1 NC_009480.1 putative proline/glycine/betaine/choline ABC transporter, substrate-binding protein (YP_062179.1| ABC-type glycine betaine transport, substrate-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055113.1| putative substrate-binding protein [Propionibacterium acnes KPA171202]). pfam04069, OpuAC, Substrate binding domain of ABC-type glycine betaine transport system. Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation.; Specificity unclear; putative proline/glycine/betaine/choline ABC transporter, substrate-binding protein 1735729 proX 5174057 proX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proline/glycine/betaine/choline ABC transporter, substrate-binding protein YP_001222274.1 1734800 D 443906 CDS YP_001222275.1 148272714 5175426 1735828..1736322 1 NC_009480.1 hypothetical protein 1736322 5175426 CMM_1533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222275.1 1735828 D 443906 CDS YP_001222276.1 148272715 5175099 1736319..1737539 1 NC_009480.1 putative chalcone synthase/polyketide synthase III (ZP_00225533.1| COG3424: Predicted naringenin-chalcone synthase [Kineococcus radiotolerans SRS30216]; ZP_00204033.1| COG3424: Predicted naringenin-chalcone synthase [Psychrobacter sp. 273-4]). pfam00195,Chal_sti_synt_N, Chalcone and stilbene synthases, N-terminal domain. The C-terminal domain of Chalcone synthase is reported to be structurally; Specificity unclear; putative chalcone synthase/polyketide synthase III 1737539 chsA 5175099 chsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chalcone synthase/polyketide synthase III YP_001222276.1 1736319 D 443906 CDS YP_001222277.1 148272716 5173634 1737539..1738261 1 NC_009480.1 putative methylase (ZP_00225534.1| COG0500: SAM-dependent methyltransferases [Kineococcus radiotolerans SRS30216]; NP_285650.1| hypothetical protein [Deinococcus radiodurans]).; Specificity unclear; hypothetical protein 1738261 5173634 CMM_1535 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222277.1 1737539 D 443906 CDS YP_001222278.1 148272717 5174056 1738258..1739448 1 NC_009480.1 putative monooxygenase (AAF12452.1| oxidoreductase,putative [Deinococcus radiodurans]; ZP_00225535.1| COG0654: 2-polyprenyl- 6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]). pfam01494, FAD_binding_3, FAD binding domain. This domain is involved in FAD binding in a number of enzymes. pfam01360, Monooxygenase,Monooxygenase. This family includes diverse enzymes that utilise FAD. InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase).; Function unclear; putative monooxygenase 1739448 5174056 CMM_1536 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001222278.1 1738258 D 443906 CDS YP_001222279.1 148272718 5175859 complement(1739441..1740286) 1 NC_009480.1 putative polyprenyltransferase (YP_061829.1| 1,4-dihydroxy- 2-naphthoate octaprenyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; CAC17489.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00004483.1| COG0382: 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Rhodobacter sphaeroides]). pfam01040, UbiA, UbiA prenyltransferase family. InterPro: UbiA prenyltransferase.; Function unclear; putative polyprenyltransferase 1740286 5175859 CMM_1537 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyprenyltransferase YP_001222279.1 1739441 R 443906 CDS YP_001222280.1 148272719 5174031 complement(1740283..1740753) 1 NC_009480.1 putative acetyltransferase (ZP_00198496.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00294382.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Thermobifida fusca]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 1740753 5174031 CMM_1538 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222280.1 1740283 R 443906 CDS YP_001222281.1 148272720 5173776 1740805..1741338 1 NC_009480.1 putative N-acetyltransferase (ZP_00170037.2| COG1247: Sortase and related acyltransferases [Ralstonia eutropha JMP134]; AAN70415.1| phosphinothricin N-acetyltransferase, putative [Pseudomonas putida KT2440]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase; Function unclear; putative N-acetyltransferase 1741338 5173776 CMM_1539 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative N-acetyltransferase YP_001222281.1 1740805 D 443906 CDS YP_001222282.1 148272721 5175508 complement(1741632..1742075) 1 NC_009480.1 hypothetical protein 1742075 5175508 CMM_1540 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222282.1 1741632 R 443906 CDS YP_001222283.1 148272722 5173241 1742453..1743865 1 NC_009480.1 cytochrome bd-type menaquinol oxidase subunit I (YP_062182.1| cytochrome D ubiquinol oxidase subunit I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628129.1| putative cytochrome oxidase subunit I [Streptomyces coelicolor A3(2)]). pfam01654, Bac_Ubq_Cox, Bacterial Cytochrome Ubiquinol Oxidase. This family are the alternative oxidases found in many bacteria which oxidise ubiquinol and reduce oxygen as part of the electron transport chain.; High confidence in function and specificity; cytochrome bd-type menaquinol oxidase subunit I 1743865 cydA 5173241 cydA Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytochrome bd-type menaquinol oxidase subunit I YP_001222283.1 1742453 D 443906 CDS YP_001222284.1 148272723 5174497 1743865..1744869 1 NC_009480.1 cytochrome bd-type menaquinol oxidase subunit II (YP_062183.1| cytochrome D ubiquinol oxidase subunit II [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628130.1| putative cytochrome oxidase subunit II [Streptomyces coelicolor A3(2)]). pfam02322, Cyto_ox_2, Cytochrome oxidase subunit II. This Family consists of cytochrome bd type terminal oxidases that catalyses Quinol dependent,Na+ independent oxygen uptake. InterPro: Cytochrome bd ubiquinol oxidase subunit II cydB: cytochrome d ubiquinol oxidase; High confidence in function and specificity; cytochrome bd-type menaquinol oxidase subunit II 1744869 cydB 5174497 cydB Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytochrome bd-type menaquinol oxidase subunit II YP_001222284.1 1743865 D 443906 CDS YP_001222285.1 148272724 5175811 1744877..1746637 1 NC_009480.1 ABC transporter, ATP-binding protein involved in cytochrome bd biosynthesis (AAP55500.1| cytochrome oxidase subunit IV [Leifsonia xyli subsp. xyli]; NP_628131.1| putative ABC transporter [Streptomyces coelicolor A3(2)]). , pfam00005, ABC_tran, ABC transporter. InterPro: ABC transporter transmembrane region; High confidence in function and specificity; ABC transporter, ATP-binding protein involved in cytochrome bd biosynthesis 1746637 cydD 5175811 cydD Clavibacter michiganensis subsp. michiganensis NCPPB 382 ABC transporter, ATP-binding protein involved in cytochrome bd biosynthesis YP_001222285.1 1744877 D 443906 CDS YP_001222286.1 148272725 5175863 1746634..1748301 1 NC_009480.1 ABC transporter, fused permease/ATP-binding protein involved in the biosynthesis of cytochrom bd (YP_062185.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293394.1| COG4987: ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; transport ATP-binding protein CydC 1748301 cydC 5175863 cydC Clavibacter michiganensis subsp. michiganensis NCPPB 382 transport ATP-binding protein CydC YP_001222286.1 1746634 D 443906 CDS YP_001222287.1 148272726 5174572 complement(1748332..1749150) 1 NC_009480.1 conserved hypothetical protein, putative 4-amino-4-deoxychorismate lyase (YP_062186.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822350.1| hypothetical protein SAV1175 [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 1749150 5174572 CMM_1545 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222287.1 1748332 R 443906 CDS YP_001222288.1 148272727 5173349 1749204..1750667 1 NC_009480.1 putative anthranilate synthase component I (YP_062187.1| anthranilate synthase component I [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44483.1| anthranilate synthase component I [Tropheryma whipplei str. Twist]). ,pfam04715, Anth_synt_I_N, Anthranilate synthase component I, N terminal region. , pfam00425, Chorismate_bind,chorismate binding enzyme.; High confidence in function and specificity; putative anthranilate synthase component I 1750667 trpE2 5173349 trpE2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anthranilate synthase component I YP_001222288.1 1749204 D 443906 CDS YP_001222289.1 148272728 5174696 1750767..1753322 1 NC_009480.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1753322 leuS 5174696 leuS Clavibacter michiganensis subsp. michiganensis NCPPB 382 leucyl-tRNA synthetase YP_001222289.1 1750767 D 443906 CDS YP_001222290.1 148272729 5175887 1753719..1754390 1 NC_009480.1 putative protein involved in DNA uptake (NP_622578.1| DNA uptake protein and related DNA-binding proteins [Thermoanaerobacter tengcongensis]; NP_789319.1| putative DNA uptake protein [Tropheryma whipplei TW08/27]).; Specificity unclear; putative protein involved in DNA uptake 1754390 5175887 CMM_1548 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein involved in DNA uptake YP_001222290.1 1753719 D 443906 CDS YP_001222291.1 148272730 5175617 1754387..1756144 1 NC_009480.1 conserved membrane protein, putatively involved in DNA uptake (ZP_00293576.1| COG0658: Predicted membrane metal-binding protein [Thermobifida fusca]). pfam03772,Competence, Competence protein. Members of this family are integral membrane proteins with 6 predicted transmembrane helices. Some members of this family have been shown to be essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane.; Function unclear; membrane protein, putatively involved in DNA uptake 1756144 5175617 CMM_1549 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putatively involved in DNA uptake YP_001222291.1 1754387 D 443906 CDS YP_001222292.1 148272731 5173997 1756230..1757258 1 NC_009480.1 DNA polymerase III, delta subunit (YP_062389.1| DNA polymerase III, delta subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626802.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]).; High confidence in function and specificity; DNA polymerase III, delta subunit 1757258 holA 5173997 holA Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III, delta subunit YP_001222292.1 1756230 D 443906 CDS YP_001222293.1 148272732 5175606 complement(1757361..1757624) 1 NC_009480.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1757624 rpsT 5175606 rpsT Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S20 YP_001222293.1 1757361 R 443906 CDS YP_001222294.1 148272733 5173937 complement(1757760..1758278) 1 NC_009480.1 putative NUDIX hydrolase (NP_822596.1| putative MutT/NUDIX-family protein [Streptomyces avermitilis MA-4680]; ZP_00058247.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Thermobifida fusca]). pfam00293, NUDIX, NUDIX domain.; Function unclear; putative NUDIX hydrolase 1758278 5173937 CMM_1552 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NUDIX hydrolase YP_001222294.1 1757760 R 443906 CDS YP_001222295.1 148272734 5174245 1758372..1759631 1 NC_009480.1 conserved hypothetical protein, putative amidohydrolase (ZP_00228134.1| COG1228: Imidazolonepropionase and related amidohydrolases [Kineococcus radiotolerans SRS30216]; NP_229522.1| conserved hypothetical protein [Thermotoga maritima]). pfam01979, Amidohydro_1, Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily. pyrC_multi: dihydroorotase multifunct; Function unclear; putative amidohydrolase 1759631 5174245 CMM_1553 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative amidohydrolase YP_001222295.1 1758372 D 443906 CDS YP_001222296.1 148272735 5173710 1759628..1760605 1 NC_009480.1 NDP sugar epimerase, putative cell-division inhibitor (ZP_00225407.2| COG1090: Predicted nucleoside-diphosphate sugar epimerase [Kineococcus radiotolerans SRS30216]; NP_244757.1| cell-division inhibitor [Bacillus halodurans C-125]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family.; Function unclear; NDP sugar epimerase, putative cell-division inhibitor 1760605 5173710 CMM_1554 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NDP sugar epimerase, putative cell-division inhibitor YP_001222296.1 1759628 D 443906 CDS YP_001222297.1 148272736 5175521 1760718..1762565 1 NC_009480.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1762565 lepA 5175521 lepA Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP-binding protein LepA YP_001222297.1 1760718 D 443906 CDS YP_001222298.1 148272737 5173358 complement(1762575..1763351) 1 NC_009480.1 Hypothetical protein; putative secreted protein 1763351 5173358 CMM_1556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222298.1 1762575 R 443906 CDS YP_001222299.1 148272738 5173368 complement(1763578..1764357) 1 NC_009480.1 Hypothetical protein; putative secreted protein 1764357 5173368 CMM_1557 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222299.1 1763578 R 443906 CDS YP_001222300.1 148272739 5175548 complement(1764671..1765447) 1 NC_009480.1 Hypothetical protein; putative secreted protein 1765447 5175548 CMM_1558 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222300.1 1764671 R 443906 CDS YP_001222301.1 148272740 5174103 1765744..1766397 1 NC_009480.1 Region start changed from 1765816 to 1765744 (72 bases); hypothetical protein 1766397 5174103 CMM_1559 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222301.1 1765744 D 443906 CDS YP_001222302.1 148272741 5174609 complement(1766420..1767121) 1 NC_009480.1 putative phosphatase (ZP_00306861.1| COG0546: Predicted phosphatases [Ferroplasma acidarmanus]; ZP_00292966.1| COG0546: Predicted phosphatases [Thermobifida fusca])., , pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family are structurally different from the alpha/ beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.,InterPro: Haloacid dehalogenase/epoxide hydrolase family ,serB: phosphoserine phosphatase SerB; Function unclear; putative phosphatase 1767121 5174609 CMM_1560 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001222302.1 1766420 R 443906 CDS YP_001222303.1 148272742 5175457 1767201..1768424 1 NC_009480.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1768424 hemN 5175457 hemN Clavibacter michiganensis subsp. michiganensis NCPPB 382 coproporphyrinogen III oxidase YP_001222303.1 1767201 D 443906 CDS YP_001222304.1 148272743 5174438 complement(1768440..1768853) 1 NC_009480.1 conserved hypothetical protein (NP_824345.1| hypothetical protein SAV3169 [Streptomyces avermitilis MA-4680]; ZP_00292803.1| hypothetical protein Tfus02001595 [Thermobifida fusca]). pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein 1768853 5174438 CMM_1562 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222304.1 1768440 R 443906 CDS YP_001222305.1 148272744 5175581 complement(1768864..1769259) 1 NC_009480.1 conserved hypothetical protein (NP_254020.1| conserved hypothetical protein [Pseudomonas aeruginosa PA01]; AAM41875.1| conserved hypothetical protein [Xanthomonas campestris pv. campestris str. ATCC 33913]).; hypothetical protein 1769259 5175581 CMM_1563 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222305.1 1768864 R 443906 CDS YP_001222306.1 148272745 5174970 1769447..1770469 1 NC_009480.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 1770469 hrcA 5174970 hrcA Clavibacter michiganensis subsp. michiganensis NCPPB 382 heat-inducible transcription repressor YP_001222306.1 1769447 D 443906 CDS YP_001222307.1 148272746 5175465 1770530..1771645 1 NC_009480.1 chaperone (YP_062381.1| DnaJ protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198394.1| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Kineococcus radiotolerans SRS30216]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. pfam00684, DnaJ_CXXCXGXG,DnaJ central domain (4 repeats). pfam01556, DnaJ_C, DnaJ C terminal region. This family consists of the C terminal region form the DnaJ protein. DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress. InterPro: DnaJ C terminal domain TIGR00270: conserved hypothetical prote; High confidence in function and specificity; chaperone 1771645 dnaJ2 5175465 dnaJ2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 chaperone YP_001222307.1 1770530 D 443906 CDS YP_001222308.1 148272747 5175008 1771648..1772406 1 NC_009480.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1772406 5175008 CMM_1566 Clavibacter michiganensis subsp. michiganensis NCPPB 382 16S ribosomal RNA methyltransferase RsmE YP_001222308.1 1771648 D 443906 CDS YP_001222309.1 148272748 5173826 1772435..1772791 1 NC_009480.1 putative HIT family hydrolase (YP_062379.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00120249.2| COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Bifidobacterium longum DJO10A]). pfam01230,HIT, HIT domain.; Function unclear; HIT family hydrolase 1772791 5173826 CMM_1567 Clavibacter michiganensis subsp. michiganensis NCPPB 382 HIT family hydrolase YP_001222309.1 1772435 D 443906 CDS YP_001222310.1 148272749 5174661 1772778..1773827 1 NC_009480.1 putative phosphate starvation-induced ATPase (YP_062378.1| phosphate starvation-induced protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826760.1| putative phosphate starvation-induced protein [Streptomyces avermitilis MA-4680]). pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.; Function unclear; putative phosphate starvation-induced ATPase 1773827 5174661 CMM_1568 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate starvation-induced ATPase YP_001222310.1 1772778 D 443906 CDS YP_001222311.1 148272750 5174938 1773824..1774285 1 NC_009480.1 putative metal-dependent hydrolase (YP_062377.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226332.1| COG0319: Predicted metal-dependent hydrolase [Kineococcus radiotolerans SRS30216]). pfam02130, UPF0054, Uncharacterized protein family UPF0054.; Function unclear; putative metalloprotease 1774285 5174938 CMM_1569 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metalloprotease YP_001222311.1 1773824 D 443906 CDS YP_001222312.1 148272751 5173789 1774294..1775616 1 NC_009480.1 conserved membrane protein (YP_062376.1| hemolysin containing CBS domains [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055649.1| conserved protein, putative hemolysin [Propionibacterium acnes KPA171202]). pfam01595,DUF21, Domain of unknown function DUF21. This transmembrane region has no known function. pfam00571,CBS, CBS domain. CBS domains are small intracellular modules of unknown function. They are mostly found in 2 or four copies within a protein. pfam03471, CorC_HlyC,Transporter associated domain. This small domain is found in a family of proteins with the pfam01595 domain and two CBS domains with this domain found at the C-terminus of the proteins, the domain is also found at the C terminus of some Na+/H+ antiporters. This domain is also found in CorC that is involved in Magnesium and cobalt efflux. The function of this domain is uncertain but might be involved in modulating transport of ion substrates.; Function unclear; hypothetical protein 1775616 5173789 CMM_1570 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222312.1 1774294 D 443906 CDS YP_001222313.1 148272752 5173942 1775609..1776661 1 NC_009480.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1776661 era 5173942 era Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP-binding protein Era YP_001222313.1 1775609 D 443906 CDS YP_001222314.1 148272753 5173405 1776773..1778284 1 NC_009480.1 putative two-component system, sensor kinase (YP_062374.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 1778284 5173405 CMM_1572 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001222314.1 1776773 D 443906 CDS YP_001222315.1 148272754 5174422 1778338..1779024 1 NC_009480.1 putative two-component system, response regulator (YP_062373.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825858.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]). cd00156, REC, Signal receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family.; Specificity unclear; putative two-component system, response regulator 1779024 5174422 CMM_1573 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001222315.1 1778338 D 443906 CDS YP_001222316.1 148272755 5173544 1779110..1780513 1 NC_009480.1 putative membrane bound esterase (YP_062370.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121628.2| COG0627: Predicted esterase [Bifidobacterium longum DJO10A]; NP_939557.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00756, Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function.; Function unclear; putative membrane bound esterase 1780513 5173544 CMM_1574 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane bound esterase YP_001222316.1 1779110 D 443906 CDS YP_001222317.1 148272756 5173575 1780510..1783086 1 NC_009480.1 conserved membrane protein (ZP_00121629.1| COG2898: Uncharacterized conserved protein [Bifidobacterium longum DJO10A]; NP_600193.1| hypothetical protein NCgl0927 [Corynebacterium glutamicum ATCC 13032]). pfam04329,DUF470, Family of unknown function (DUF470). pfam04330,DUF471, Family of unknown function (DUF471). pfam04331,DUF472, Family of unknown function (DUF472). gntP: gluconate transporter; Function unclear; hypothetical protein 1783086 5173575 CMM_1575 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222317.1 1780510 D 443906 CDS YP_001222318.1 148272757 5175499 1783252..1785018 1 NC_009480.1 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (YP_062368.1| 2-isopropylmalate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226323.1| COG0119: Isopropylmalate/homocitrate/ citramalate synthases [Kineococcus radiotolerans SRS30216]).; High confidence in function and specificity; 2-isopropylmalate synthase 1785018 leuA 5175499 leuA Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-isopropylmalate synthase YP_001222318.1 1783252 D 443906 CDS YP_001222319.1 148272758 5175914 complement(1785110..1785787) 1 NC_009480.1 conserved membrane protein (YP_062367.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_718896.1| conserved hypothetical protein [Shewanella oneidensis MR-1]). pfam03458, UPF0126, UPF0126 domain. Domain always found as pair in bacterial membrane proteins of unknown function. This domain contains three transmembrane helices. The conserved glycines are suggestive of an ion channel (C. Yeats unpublished obs.)(duplicated).; hypothetical protein 1785787 5175914 CMM_1577 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222319.1 1785110 R 443906 CDS YP_001222320.1 148272759 5174886 1785906..1786835 1 NC_009480.1 DNA repair protein/recombination protein (Q9L2H3|RECO_STRCO DNA repair protein recO (Recombination protein O); ZP_00226321.1| COG1381: Recombinational DNA repair protein (RecF pathway)[Kineococcus radiotolerans SRS30216]). pfam02565, RecO, Recombination protein O.; High confidence in function and specificity; DNA repair protein /recombination protein 1786835 recO 5174886 recO Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA repair protein /recombination protein YP_001222320.1 1785906 D 443906 CDS YP_001222321.1 148272760 5172948 1786832..1787698 1 NC_009480.1 putative undecaprenyl pyrophosphate synthetase (YP_062365.1| undecaprenyl pyrophosphate synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82BS5|UPS2_STRAW Undecaprenyl pyrophosphate synthetase 2 (UPP synthetase 2)(Di-trans-poly-cis-decaprenylcistransferase 2)). , pfam01255,UPP_synthetase, Putative undecaprenyl diphosphate synthase. , InterPro: Undecaprenyl pyrophosphate synthetase family; High confidence in function and specificity; putative undecaprenyl pyrophosphate synthetase 1787698 uppS1 5172948 uppS1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl pyrophosphate synthetase YP_001222321.1 1786832 D 443906 CDS YP_001222322.1 148272761 5173490 1787708..1788817 1 NC_009480.1 putative oxidoreductase (NP_627076.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]; AAT60489.1| oxidoreductase, Gfo/Idh/MocA family [Bacillus thuringiensis serovar konkukian str. 97-27]). pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Function unclear; putative oxidoreductase 1788817 5173490 CMM_1580 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222322.1 1787708 D 443906 CDS YP_001222323.1 148272762 5173365 1788928..1790313 1 NC_009480.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1790313 glyS 5173365 glyS Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycyl-tRNA synthetase YP_001222323.1 1788928 D 443906 CDS YP_001222324.1 148272763 5173792 complement(1790365..1790829) 1 NC_009480.1 conserved hypothetical protein (YP_056922.1| putative transcriptional regulator [Propionibacterium acnes KPA171202]; NP_484703.1| probable transcription regulator [Nostoc sp. PCC 7120]). pfam04073, YbaK, YbaK / prolyl-tRNA synthetases associated domain. This domain of unknown function is found in numerous prokaryote organisms.; hypothetical protein 1790829 5173792 CMM_1582 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222324.1 1790365 R 443906 CDS YP_001222325.1 148272764 5174613 1790950..1791675 1 NC_009480.1 conserved hypothetical protein (ZP_00226827.1| COG2761: Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Kineococcus radiotolerans SRS30216]; NP_294382.1| frnE protein [Deinococcus radiodurans]; CAF21228.1| Predicted dithiol-disulfide isomerase [Corynebacterium glutamicum ATCC 13032]). pfam01323, DSBA, DSBA-like thioredoxin domain. This family contains a diverse set of proteins with a thioredoxin-like structure pfam00085. This family also includes 2-hydroxychromene-2-carboxylate (HCCA) isomerase enzymes catalyse one step in prokaryotic polyaromatic hydrocarbon (PAH) catabolic pathways.; Function unclear; hypothetical protein 1791675 5174613 CMM_1583 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222325.1 1790950 D 443906 CDS YP_001222326.1 148272765 5175005 1791958..1793190 1 NC_009480.1 putative tRNA-dihydrouridine synthase (ZP_00225742.1| COG0042: tRNA-dihydrouridine synthase [Kineococcus radiotolerans SRS30216]; NP_626738.1| conserved hypothetical protein SCC82.03c [Streptomyces coelicolor A3(2)]). Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity). pfam01207, Dus, Dihydrouridine synthase (Dus). Members of this family catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA.; Specificity unclear; putative tRNA-dihydrouridine synthase 1793190 dusA 5175005 dusA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tRNA-dihydrouridine synthase YP_001222326.1 1791958 D 443906 CDS YP_001222327.1 148272766 5175694 1793195..1794454 1 NC_009480.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 1794454 dgtA 5175694 dgtA Clavibacter michiganensis subsp. michiganensis NCPPB 382 deoxyguanosinetriphosphate triphosphohydrolase-like protein YP_001222327.1 1793195 D 443906 CDS YP_001222328.1 148272767 5175675 1794549..1796438 1 NC_009480.1 synthesizes RNA primers at the replication forks; DNA primase 1796438 dnaG 5175675 dnaG Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA primase YP_001222328.1 1794549 D 443906 CDS YP_001222329.1 148272768 5175897 1796639..1798294 1 NC_009480.1 putative oligopeptide ABC transporter, substrate-binding protein (YP_061855.1| ABC transporter, solute-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696509.1| probable solute-binding protein of ABC transporter for peptides [Bifidobacterium longum NCC2705]; NP_827846.1| putative solute binding transport lipoprotein [Streptomyces avermitilis MA-4680]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative oligopeptide ABC transporter, substrate-binding protein 1798294 5175897 CMM_1587 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, substrate-binding protein YP_001222329.1 1796639 D 443906 CDS YP_001222330.1 148272769 5173991 1798439..1799533 1 NC_009480.1 putative oligopeptide ABC transporter, permease component (YP_061856.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696510.1| probable permease of ABC transporter for peptides [Bifidobacterium longum NCC2705]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter, permease component 1799533 5173991 CMM_1588 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001222330.1 1798439 D 443906 CDS YP_001222331.1 148272770 5174937 1799535..1800557 1 NC_009480.1 putative oligopeptide ABC transporter, permease component(ZP_00120658.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Bifidobacterium longum DJO10A]; YP_061857.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter, permease component 1800557 5174937 CMM_1589 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001222331.1 1799535 D 443906 CDS YP_001222332.1 148272771 5174707 1800554..1802266 1 NC_009480.1 putative oligopeptide ABC transporter, ATP-binding protein (duplicated ATPase domain; YP_061858.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696512.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]).; Specificity unclear; putative oligopeptide ABC transporter, ATP-binding protein 1802266 5174707 CMM_1590 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, ATP-binding protein YP_001222332.1 1800554 D 443906 CDS YP_001222333.1 148272772 5175616 1802380..1803327 1 NC_009480.1 putative oligopeptide ABC transporter, ATP-binding protein (YP_061859.1| oligopeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_798466.1| oligopeptide ABC transporter, ATP-binding protein [Vibrio parahaemolyticus RIMD 2210633]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative oligopeptide ABC transporter, ATP-binding protein 1803327 5175616 CMM_1591 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, ATP-binding protein YP_001222333.1 1802380 D 443906 CDS YP_001222334.1 148272773 5174276 1803438..1804343 1 NC_009480.1 putative 2-hydroxyacid dehydrogenase (YP_061860.1| phosphoglycerate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226123.1| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam02826, 2-Hacid_dh_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain.; Specificity unclear; putative 2-hydroxyacid dehydrogenase 1804343 5174276 CMM_1592 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2-hydroxyacid dehydrogenase YP_001222334.1 1803438 D 443906 CDS YP_001222335.1 148272774 5175613 1804431..1805438 1 NC_009480.1 conserved hypothetical protein (ZP_00058653.1| COG2706: 3-carboxymuconate cyclase [Thermobifida fusca]; NP_822705.1| putative secreted protein [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 1805438 5175613 CMM_1593 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222335.1 1804431 D 443906 CDS YP_001222336.1 148272775 5175513 complement(1805458..1805826) 1 NC_009480.1 hypothetical protein 1805826 5175513 CMM_1594 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222336.1 1805458 R 443906 CDS YP_001222337.1 148272776 5173677 complement(1806057..1806623) 1 NC_009480.1 putative polypeptide deformylase (YP_061861.1| polypeptide deformylase [Leifsonia xyli subsp. xyli str. CTCB07]; Q83HQ3|DEF_TROW8 Peptide deformylase (PDF) (Polypeptide deformylase); P96275|DEF_MYCTU Peptide deformylase (PDF) (Polypeptide deformylase)). pfam01327,Pep_deformylase, Polypeptide deformylase.; High confidence in function and specificity; putative polypeptide deformylase 1806623 defA 5173677 defA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polypeptide deformylase YP_001222337.1 1806057 R 443906 CDS YP_001222338.1 148272777 5173787 1806663..1807574 1 NC_009480.1 conserved membrane protein, putative transporter of the DMT family (YP_061862.1| Integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789391.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00059265.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Thermobifida fusca]).; Family membership; exporter DMT family membrane protein 1807574 wcmE 5173787 wcmE Clavibacter michiganensis subsp. michiganensis NCPPB 382 exporter DMT family membrane protein YP_001222338.1 1806663 D 443906 CDS YP_001222339.1 148272778 5174868 1807755..1809014 1 NC_009480.1 putative glycosyltransferase (YP_061863.1| glucosyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787440.1| glycosyltransferase [Tropheryma whipplei str. Twist]; ZP_00058706.1| COG0438: Glycosyltransferase [Thermobifida fusca]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1; Specificity unclear; putative glycosyltransferase 1809014 wcmF 5174868 wcmF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001222339.1 1807755 D 443906 CDS YP_001222340.1 148272779 5175638 1809356..1811548 1 NC_009480.1 putative membrane-.bound acyltranferase (ZP_00057849.1| COG1835: Predicted acyltransferases [Thermobifida fusca]; NP_962944.1| hypothetical protein MAP4010c [Mycobacterium avium subsp. paratuberculosis str. k10]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltranferase 1811548 wcmG 5175638 wcmG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound acyltranferase YP_001222340.1 1809356 D 443906 CDS YP_001222341.1 148272780 5173332 complement(1811648..1812652) 1 NC_009480.1 putative fucose synthase (GDP-4-keto-6-deoxy-D-mannose- 3,5-epimerase-4-reductase) (NP_336015.1| fucose synthetase [Mycobacterium tuberculosis CDC1551]; ZP_00199161.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]). pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor.; High confidence in function and specificity; hypothetical protein 1812652 fclA 5173332 fclA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222341.1 1811648 R 443906 CDS YP_001222342.1 148272781 5175117 complement(1812649..1813701) 1 NC_009480.1 putative D-GDP-mannose dehydratase (EC 4.2.1.47) (AAN05764.1| GDP-D-mannose-dehydratase MdhtA [Mycobacterium avium]; ZP_00227152.1| COG1089: GDP-D-mannose dehydratase [Kineococcus radiotolerans SRS30216]). Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose (By similarity). PUTATIVELY INVOLVED IN EPS BIOSYNTHESIS pfam01370, Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; High confidence in function and specificity; putative GDP-mannose 4,6-dehydratase 1813701 gmdA 5175117 gmdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative GDP-mannose 4,6-dehydratase YP_001222342.1 1812649 R 443906 CDS YP_001222343.1 148272782 5173531 1813877..1815163 1 NC_009480.1 putative glycosyl transferase (ZP_00225721.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; ZP_00049876.2| COG0438: Glycosyltransferase [Magnetospirillum magnetotacticum]; NP_707945.1| putative colanic biosynthesis glycosyl transferase [Shigella flexneri 2a str. 301]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyltransferase 1815163 wcmH 5173531 wcmH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001222343.1 1813877 D 443906 CDS YP_001222344.1 148272783 5172946 1815160..1815744 1 NC_009480.1 putative acetyltransferase involved in polysaccharide biosynthesis (ZP_00033229.1| COG0110: Acetyltransferase (isoleucine patch superfamily)[Burkholderia fungorum]; NP_864963.1| putative colanic acid biosynthesis acetyltransferase [Pirellula sp. 1]; ZP_00227153.1| COG0110: Acetyltransferase (isoleucine patch superfamily)[Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative acetyltransferase involved in polysaccharide biosynthesis 1815744 wcmI 5172946 wcmI Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase involved in polysaccharide biosynthesis YP_001222344.1 1815160 D 443906 CDS YP_001222345.1 148272784 5172978 1815849..1816784 1 NC_009480.1 putative pyruvyltransferase (YP_009110.1| conserved domain protein [Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough]; only weak similarities to: CAB01946.1| ExpA4 [Sinorhizobium meliloti]; AMSJ_ERWAM Amylovoran biosynthesis protein amsJ). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam04230, PS_pyruv_trans,Polysaccharide pyruvyl transferase. Pyruvyl-transferases involved in peptidoglycan-associated polymer biosynthesis.; Hypothetical protein; putative pyruvyltransferase 1816784 wcmJ 5172978 wcmJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyruvyltransferase YP_001222345.1 1815849 D 443906 CDS YP_001222346.1 148272785 5172988 1816781..1818013 1 NC_009480.1 putative glycosyl transferase (sp|P71237|WCAC_ECOLI Putative colanic acid biosynthesis glycosyl transferase wcaC; NP_707952.1| putative glycosyl transferase [Shigella flexneri 2a str. 301]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; putative glycosyl transferase 1818013 wcmK 5172988 wcmK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001222346.1 1816781 D 443906 CDS YP_001222347.1 148272786 5172990 1818010..1819293 1 NC_009480.1 wzy1; essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 1819293 wcaD 5172990 wcaD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative colanic acid biosynthesis protein YP_001222347.1 1818010 D 443906 CDS YP_001222348.1 148272787 5174012 1819193..1819942 1 NC_009480.1 Region start changed from 1819358 to 1819193 (165 bases); putative glycosyl transferase 1819942 5174012 CMM_1606 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001222348.1 1819193 D 443906 CDS YP_001222349.1 148272788 5175886 1819939..1820442 1 NC_009480.1 putative serine acetyltransferase (NP_745280.1| serine O-acetyltransferase, putative [Pseudomonas putida KT2440]; NP_228475.1| serine acetyltransferase [Thermotoga maritima]) . PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. InterPro: Bacterial transferase hexapeptide repeat; Specificity unclear; putative serine acetyltransferase 1820442 wcmM 5175886 wcmM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine acetyltransferase YP_001222349.1 1819939 D 443906 CDS YP_001222350.1 148272789 5173007 1820477..1821901 1 NC_009480.1 putative membrane protein involved in the synthesis/export of EPS (NP_105963.1| probable succinoglycan transport protein [Mesorhizobium loti]; NP_266368.1| polysaccharide biosynthesis export protein [Lactococcus lactis subsp. lactis]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam01943, Polysacc_synt,Polysaccharide biosynthesis protein. Members of this family are integral membrane proteins.; Family membership; putative membrane protein involved in the export of EPS 1821901 wzx1 5173007 wzx1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane protein involved in the export of EPS YP_001222350.1 1820477 D 443906 CDS YP_001222351.1 148272790 5173981 complement(1821917..1823482) 1 NC_009480.1 putative undecaprenyl-phosphate glycosyl-1-phosphate transferase (NP_959898.1| hypothetical protein MAP0964c [Mycobacterium avium subsp. paratuberculosis str. k10]; AAM94041.1| putative undecaprenyl-phosphate glycosyl-1-phosphate transferase; glucose-1-phosphate transferase [Streptomyces sp. 139]; NP_695455.1| undecaprenyl-phosphate sugar phosphotransferase [Bifidobacterium longum NCC2705]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF EPS. pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.; Specificity unclear; putative undecaprenyl-phosphate glycosyl-1-phosphate transfe 1823482 wcmN 5173981 wcmN Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl-phosphate glycosyl-1-phosphate transfe YP_001222351.1 1821917 R 443906 CDS YP_001222352.1 148272791 5173051 complement(1823628..1823915) 1 NC_009480.1 hypothetical protein (ZP_00049742.1| hypothetical protein Magn023325 [Magnetospirillum magnetotacticum]).; hypothetical protein 1823915 5173051 CMM_1610 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222352.1 1823628 R 443906 CDS YP_001222353.1 148272792 5173743 complement(1824033..1824236) 1 NC_009480.1 putative cold shock protein A (ZP_00047730.1| COG1278: Cold shock proteins [Magnetospirillum magnetotacticum]; YP_063017.1| cold shock protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00313, CSD,'Cold-shock' DNA-binding domain. InterPro: Cold-shock DNA-binding domain; Family membership; putative cold shock protein 1824236 cspA1 5173743 cspA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cold shock protein YP_001222353.1 1824033 R 443906 CDS YP_001222354.1 148272793 5174602 1824495..1826165 1 NC_009480.1 putative DNA polymerase I (YP_061866.1| DNA polymerase I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733604.1| putative DNA polymerase I [Streptomyces coelicolor A3(2)]). pfam00476, DNA_pol_A, DNA polymerase family A. InterPro: Replicative DNA polymerase; Specificity unclear; putative DNA polymerase I 1826165 polA2 5174602 polA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA polymerase I YP_001222354.1 1824495 D 443906 CDS YP_001222355.1 148272794 5173186 1826256..1826405 1 NC_009480.1 hypothetical protein 1826405 5173186 CMM_1612A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222355.1 1826256 D 443906 CDS YP_001222356.1 148272795 5173393 1826513..1827364 1 NC_009480.1 conserved hypothetical protein (YP_061867.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626020.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1827364 5173393 CMM_1613 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222356.1 1826513 D 443906 CDS YP_001222357.1 148272796 5174169 complement(1827366..1827968) 1 NC_009480.1 putative transcriptional regulator, PadR family (YP_054926.1| transcriptional regulator [Propionibacterium acnes KPA171202]; NP_737543.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03551,PadR, Transcriptional regulator PadR-like family.; Specificity unclear; PadR family transcriptional regulator 1827968 5174169 CMM_1614 Clavibacter michiganensis subsp. michiganensis NCPPB 382 PadR family transcriptional regulator YP_001222357.1 1827366 R 443906 CDS YP_001222358.1 148272797 5175488 1828232..1828750 1 NC_009480.1 conserved hypothetical protein (YP_061869.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00190504.2| hypothetical protein Krad06002672 [Kineococcus radiotolerans SRS30216]; NP_826961.1| hypothetical protein SAV5784 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1828750 5175488 CMM_1615 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222358.1 1828232 D 443906 CDS YP_001222359.1 148272798 5174099 complement(1828844..1830085) 1 NC_009480.1 3-oxoacyl-[acyl-carrier-protein] synthase 1 (Beta-ketoacyl-ACP synthase 1) (YP_062220.1| 3-oxoacyl-[acyl-carrier-protein] synthase I [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226800.1| COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Kineococcus radiotolerans SRS30216]). Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity). pfam00109,ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain. pfam02801, Ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain. InterPro: Beta-ketoacyl synthase.; High confidence in function and specificity; 3-oxoacyl-[acyl-carrier-protein] synthase 1830085 fabF 5174099 fabF Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-oxoacyl-[acyl-carrier-protein] synthase YP_001222359.1 1828844 R 443906 CDS YP_001222360.1 148272799 5173830 complement(1830165..1830413) 1 NC_009480.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1830413 acpP 5173830 acpP Clavibacter michiganensis subsp. michiganensis NCPPB 382 acyl carrier protein YP_001222360.1 1830165 R 443906 CDS YP_001222361.1 148272800 5175682 complement(1830467..1831480) 1 NC_009480.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 1831480 fabH 5175682 fabH Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-oxoacyl-(acyl carrier protein) synthase III YP_001222361.1 1830467 R 443906 CDS YP_001222362.1 148272801 5175415 complement(1831511..1832431) 1 NC_009480.1 putative malonyl CoA-acyl carrier protein transacylase (YP_062217.1| [acyl-carrier protein] S-malonyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626633.1| malonyl CoA:acyl carrier protein malonyltransferase [Streptomyces coelicolor A3(2)]). pfam00698, Acyl_transf_1, Acyl transferase domain. InterPro: Acyl transferase domain fabD: malonyl CoA-acyl carrier protein; High confidence in function and specificity; putative malonyl CoA-acyl carrier protein transacylase 1832431 fabD 5175415 fabD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative malonyl CoA-acyl carrier protein transacylase YP_001222362.1 1831511 R 443906 CDS YP_001222363.1 148272802 5174342 complement(1832526..1833800) 1 NC_009480.1 putative transcriptional regulator (YP_062216.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826966.1| hypothetical protein SAV5789 [Streptomyces avermitilis MA-4680]).; Function unclear; putative transcriptional regulator 1833800 5174342 CMM_1620 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001222363.1 1832526 R 443906 CDS YP_001222364.1 148272803 5173148 complement(1833817..1836543) 1 NC_009480.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1836543 aceE 5173148 aceE Clavibacter michiganensis subsp. michiganensis NCPPB 382 pyruvate dehydrogenase subunit E1 YP_001222364.1 1833817 R 443906 CDS YP_001222365.1 148272804 5173231 1836784..1837257 1 NC_009480.1 putative thiol-specific antioxidant protein,thioredoxin peroxidase (YP_062214.1| AhpC/TSA family protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626616.1| putative thiol-specific antioxidant protein [Streptomyces coelicolor A3(2)]). pfam00578, AhpC-TSA,AhpC/TSA family. This family contains proteins related to alkyl hydroperoxide reductase (AhpC) and thiol specific antioxidant (TSA).; Family membership; putative thiol-specific antioxidant protein 1837257 ahpE 5173231 ahpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thiol-specific antioxidant protein YP_001222365.1 1836784 D 443906 CDS YP_001222366.1 148272805 5173039 complement(1837286..1837975) 1 NC_009480.1 putative membrane protein (NP_103276.1| unknown protein [Mesorhizobium loti MAFF303099]; NP_868937.1| conserved hypothetical protein [Pirellula sp. 1]). pfam07077, DUF1345, Protein of unknown function (DUF1345).; hypothetical protein 1837975 5173039 CMM_1623 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222366.1 1837286 R 443906 CDS YP_001222367.1 148272806 5174721 complement(1838182..1838772) 1 NC_009480.1 putative transcriptional regulator, TetR family (YP_062890.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056115.1| tetracycline repressor protein [Propionibacterium acnes KPA171202]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.; Specificity unclear; TetR family transcriptional regulator 1838772 5174721 CMM_1624 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001222367.1 1838182 R 443906 CDS YP_001222368.1 148272807 5173473 1838853..1839494 1 NC_009480.1 conserved membrane protein, BioY-family (YP_062891.1| biotin synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_979945.1| bioY family protein [Bacillus cereus ATCC 10987]; NP_787339.1| biotin synthesis BioY protein [Tropheryma whipplei str. Twist]) pfam02632, BioY,BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin.; Conserved hypothetical protein; membrane protein BioY family 1839494 5173473 CMM_1625 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein BioY family YP_001222368.1 1838853 D 443906 CDS YP_001222369.1 148272808 5174085 1839509..1840195 1 NC_009480.1 putative metal ABC transporter, ATP-binding protein (YP_062894.1| ABC- transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00269416.1| COG1122: ABC-type cobalt transport system, ATPase component [Rhodospirillum rubrum]). pfam00005, ABC_tran,ABC transporter. InterPro: AAA ATPase superfamily; Specificity unclear; putative metal ABC transporter, ATP-binding protein 1840195 5174085 CMM_1626 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, ATP-binding protein YP_001222369.1 1839509 D 443906 CDS YP_001222370.1 148272809 5173688 1840192..1840803 1 NC_009480.1 putative metal ABC transporter, permease component (YP_062895.1| ABC-type cobalt transport system, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00271172.1| COG0619: ABC-type cobalt transport system,permease component CbiQ and related transporters [Rhodospirillum rubrum]). pfam02361, CbiQ, Cobalt transport protein.; Specificity unclear; putative metal ABC transporter, permease component 1840803 5173688 CMM_1627 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, permease component YP_001222370.1 1840192 D 443906 CDS YP_001222371.1 148272810 5172919 1840889..1841080 1 NC_009480.1 hypothetical protein 1841080 5172919 CMM_1628 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222371.1 1840889 D 443906 CDS YP_001222372.1 148272811 5174112 1841133..1841960 1 NC_009480.1 conserved hypothetical protein (YP_061971.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789442.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; ZP_00059437.1| COG0327: Uncharacterized conserved protein [Thermobifida fusca]). pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). TIGR00486: conserved hypothetical prote; Function unclear; hypothetical protein 1841960 5174112 CMM_1629 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222372.1 1841133 D 443906 CDS YP_001222373.1 148272812 5172930 1842052..1842786 1 NC_009480.1 conserved hypothetical protein (YP_061972.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226791.1| COG1579: Zn-ribbon protein,nucleic acid-binding [Kineococcus radiotolerans SRS30216]). pfam02591, DUF164, Uncharacterized ACR,COG1579. InterPro: DUF164; Function unclear; hypothetical protein 1842786 5172930 CMM_1630 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222373.1 1842052 D 443906 CDS YP_001222374.1 148272813 5174801 complement(1843281..1844102) 1 NC_009480.1 putative polyphosphate glucokinase (Polyphosphate-glucose phosphotransferase) (YP_061973.1| glucokinase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056789.1| polyphosphate glucokinase/ transcriptional regulator [Propionibacterium acnes KPA171202]). , pfam00480, ROK,ROK family. , glk: glucokinase; Specificity unclear; putative polyphosphate glucokinase 1844102 ppgK1 5174801 ppgK1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyphosphate glucokinase YP_001222374.1 1843281 R 443906 CDS YP_001222375.1 148272814 5175118 1844177..1844359 1 NC_009480.1 conserved hypothetical protein (NP_940013.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]; ZP_00121553.1| hypothetical protein Blon021481 [Bifidobacterium longum DJO10A]).; hypothetical protein 1844359 5175118 CMM_1632 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222375.1 1844177 D 443906 CDS YP_001222376.1 148272815 5172944 complement(1844369..1845238) 1 NC_009480.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1845238 panB 5172944 panB Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_001222376.1 1844369 R 443906 CDS YP_001222377.1 148272816 5175400 1845324..1846661 1 NC_009480.1 putative glutamine synthetase II (Glutamate--ammonia ligase 2)(YP_061977.1| glutamine synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226485.1| COG0174: Glutamine synthetase [Kineococcus radiotolerans SRS30216]). pfam03951, Gln-synt_N, Glutamine synthetase,beta-Grasp domain. pfam00120, Gln-synt_C, Glutamine synthetase, catalytic domain. InterPro: Glutamine synthetase.; High confidence in function and specificity; putative glutamine synthetase II 1846661 glnA2 5175400 glnA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamine synthetase II YP_001222377.1 1845324 D 443906 CDS YP_001222378.1 148272817 5175002 1846720..1849740 1 NC_009480.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 1849740 glnE 5175002 glnE Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_001222378.1 1846720 D 443906 CDS YP_001222379.1 148272818 5175158 complement(1849834..1851258) 1 NC_009480.1 Glutamine synthetase I (Glutamate--ammonia ligase) (YP_061980.1| glutamine synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198695.2| COG0174: Glutamine synthetase [Kineococcus radiotolerans SRS30216]). pfam03951, Gln-synt_N, Glutamine synthetase, beta-Grasp domain. pfam00120, Gln-synt_C, Glutamine synthetase,catalytic domain. GlnA: glutamine synthetase type I; High confidence in function and specificity; glutamine synthetase I 1851258 glnA1 5175158 glnA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamine synthetase I YP_001222379.1 1849834 R 443906 CDS YP_001222380.1 148272819 5173611 1851451..1851879 1 NC_009480.1 conserved membrane protein (YP_061981.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626449.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00189987.2| COG1714: Predicted membrane protein/domain [Kineococcus radiotolerans SRS30216]). pfam06271, RDD, RDD family.; Function unclear; hypothetical protein 1851879 5173611 CMM_1637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222380.1 1851451 D 443906 CDS YP_001222381.1 148272820 5173475 complement(1851905..1852630) 1 NC_009480.1 putative chaperone ( pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction.; Family membership; putative chaperone 1852630 5173475 CMM_1638 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chaperone YP_001222381.1 1851905 R 443906 CDS YP_001222382.1 148272821 5174008 complement(1852685..1853395) 1 NC_009480.1 conserved membrane protein (YP_061982.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198696.2| hypothetical protein Krad06003323 [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 1853395 5174008 CMM_1639 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222382.1 1852685 R 443906 CDS YP_001222383.1 148272822 5173580 1853609..1855297 1 NC_009480.1 putative serine/threonine protein kinase (AAO44694.1| putative serine/threonine-protein kinase [Tropheryma whipplei str. Twist]; NP_601379.1| serine/threonine protein kinase [Corynebacterium glutamicum ATCC 13032]). pfam00069, Pkinase, Protein kinase domain. smart00220, S_TKc, Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily.; Family membership; putative serine/threonine protein kinase 1855297 pknD 5173580 pknD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine protein kinase YP_001222383.1 1853609 D 443906 CDS YP_001222384.1 148272823 5173470 complement(1855324..1856766) 1 NC_009480.1 putative pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component (YP_061986.1| dihydrolipoamide acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789198.1| putative lipoamide acyltransferase [Tropheryma whipplei TW08/27]). pfam00364, Biotin_lipoyl, Biotin-requiring enzyme. pfam02817, E3_binding, e3 binding domain. This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. pfam00198, 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain).; Specificity unclear; putative pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component 1856766 aceF 5173470 aceF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component YP_001222384.1 1855324 R 443906 CDS YP_001222385.1 148272824 5173423 complement(1856827..1858200) 1 NC_009480.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1858200 lpdB 5173423 lpdB Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydrolipoamide dehydrogenase YP_001222385.1 1856827 R 443906 CDS YP_001222386.1 148272825 5174383 complement(1858292..1859800) 1 NC_009480.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 1859800 pepA 5174383 pepA Clavibacter michiganensis subsp. michiganensis NCPPB 382 leucyl aminopeptidase YP_001222386.1 1858292 R 443906 CDS YP_001222387.1 148272826 5175189 1859970..1860890 1 NC_009480.1 conserved hypothetical protein (YP_061989.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058376.1| hypothetical protein [Thermobifida fusca]; NP_961765.1| hypothetical protein MAP2831 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam05601, DUF774, Protein of unknown function (DUF774). This family consists of several uncharacterised Actinomycete proteins of unknown function.; Function unclear; hypothetical protein 1860890 5175189 CMM_1644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222387.1 1859970 D 443906 CDS YP_001222388.1 148272827 5174752 1860965..1862287 1 NC_009480.1 putative MFS permease (YP_061990.1| major facilitator superfamily permease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226285.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative MFS permease 1862287 5174752 CMM_1645 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001222388.1 1860965 D 443906 CDS YP_001222389.1 148272828 5173366 1862537..1864015 1 NC_009480.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; RNA polymerase sigma factor 1864015 sigA 5173366 sigA Clavibacter michiganensis subsp. michiganensis NCPPB 382 RNA polymerase sigma factor YP_001222389.1 1862537 D 443906 CDS YP_001222390.1 148272829 5175188 1864019..1865299 1 NC_009480.1 putative UDP-N-acetylmuramyl tripeptide synthase(YP_061992.1| UDP-N-acetylmuramyl tripeptide synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787626.1| UDP-N-acetylmuramyl tripeptide synthase-like protein [Tropheryma whipplei str. Twist]). , pfam01225,Mur_ligase, Mur ligase family, catalytic domain. ,InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; High confidence in function and specificity; putative UDP-N-acetylmuramyl tripeptide synthase 1865299 murX 5175188 murX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-N-acetylmuramyl tripeptide synthase YP_001222390.1 1864019 D 443906 CDS YP_001222391.1 148272830 5173228 1865296..1866030 1 NC_009480.1 putative glutamine amidotransferase (YP_061993.1| cobyric acid synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_621720.1| predicted glutamine amidotransferase [Thermoanaerobacter tengcongensis]; AAC84011.1| cobyric acid synthase CobQ [Heliobacillus mobilis]).; Function unclear; putative glutamine amidotransferase 1866030 5173228 CMM_1648 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamine amidotransferase YP_001222391.1 1865296 D 443906 CDS YP_001222392.1 148272831 5173140 complement(1866133..1866360) 1 NC_009480.1 conserved hypothetical protein (YP_062003.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226189.1| hypothetical protein Krad06003778 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1866360 5173140 CMM_1649 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222392.1 1866133 R 443906 CDS YP_001222393.1 148272832 5174670 1866573..1868651 1 NC_009480.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1868651 5174670 CMM_1650 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA topoisomerase IV subunit B YP_001222393.1 1866573 D 443906 CDS YP_001222394.1 148272833 5173479 complement(1868733..1871279) 1 NC_009480.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1871279 5173479 CMM_1651 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA topoisomerase IV subunit A YP_001222394.1 1868733 R 443906 CDS YP_001222395.1 148272834 5173495 1871364..1872503 1 NC_009480.1 conserved hypothetical protein (ZP_00226205.1| COG1524: Uncharacterized proteins of the AP superfamily [Kineococcus radiotolerans SRS30216]; ZP_00291972.1| COG1524: Uncharacterized proteins of the AP superfamily [Thermobifida fusca]). pfam01663, Phosphodiest, Type I phosphodiesterase/nucleotide pyrophosphatase.; hypothetical protein 1872503 5173495 CMM_1652 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222395.1 1871364 D 443906 CDS YP_001222396.1 148272835 5173564 complement(1872559..1873749) 1 NC_009480.1 putative DNA-binding protein (NP_789210.1| conserved DNA-binding protein [Tropheryma whipplei TW08/27]; NP_629978.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1873749 5173564 CMM_1653 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222396.1 1872559 R 443906 CDS YP_001222397.1 148272836 5173990 1874075..1874368 1 NC_009480.1 conserved hypothetical protein (YP_062008.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226691.1| hypothetical protein Krad06002945 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 1874368 5173990 CMM_1654 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222397.1 1874075 D 443906 CDS YP_001222398.1 148272837 5173134 complement(1874416..1874865) 1 NC_009480.1 putative membrane protein (NP_789212.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_629988.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 1874865 5173134 CMM_1655 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222398.1 1874416 R 443906 CDS YP_001222399.1 148272838 5173488 1874904..1875374 1 NC_009480.1 putative deoxyuridine 5'-triphosphate pyrophosphatase (NP_823575.1| putative deoxyuridine 5'-triphosphate pyrophosphatase [Streptomyces avermitilis MA-4680]; NP_789213.1| deoxyuridine 5'-triphosphate nucleotidohydrolase [Tropheryma whipplei TW08/27]). pfam00692, dUTPase, dUTPase. dUTPase hydrolyses dUTP to dUMP and pyrophosphate.; High confidence in function and specificity; hypothetical protein 1875374 dutA 5173488 dutA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222399.1 1874904 D 443906 CDS YP_001222400.1 148272839 5174465 1875371..1876063 1 NC_009480.1 conserved hypothetical protein (NP_787614.1| unknown [Tropheryma whipplei str. Twist]; NP_823574.1| hypothetical protein SAV2398 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1876063 5174465 CMM_1657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222400.1 1875371 D 443906 CDS YP_001222401.1 148272840 5172949 1876066..1876857 1 NC_009480.1 conserved membrane protein (NP_629996.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_696556.1| narrowly conserved hypothetical transmembrane protein [Bifidobacterium longum NCC2705]).; Conserved hypothetical protein; hypothetical protein 1876857 5172949 CMM_1658 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222401.1 1876066 D 443906 CDS YP_001222402.1 148272841 5173139 1877093..1879906 1 NC_009480.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1879906 acnA 5173139 acnA Clavibacter michiganensis subsp. michiganensis NCPPB 382 aconitate hydratase YP_001222402.1 1877093 D 443906 CDS YP_001222403.1 148272842 5175323 1879985..1881973 1 NC_009480.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 1881973 dxsA 5175323 dxsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 1-deoxy-D-xylulose-5-phosphate synthase YP_001222403.1 1879985 D 443906 CDS YP_001222404.1 148272843 5174595 complement(1882035..1884164) 1 NC_009480.1 Fatty oxidation complex alpha subunit (ZP_00294150.1| COG1250: 3-hydroxyacyl-CoA dehydrogenase [Thermobifida fusca]; NP_823410.1| putative fatty acid oxidation complex alpha-subunit [Streptomyces avermitilis MA-4680]). FAOA AND FAOB ARE THE ALPHA AND BETA SUBUNITS OF THE MULTIFUNCTIONAL ENZYME COMPLEX OF THE FATTY ACID DEGRADATION CYCLE. N-terminal: COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase; pfam00378, ECH, Enoyl-CoA hydratase/isomerase family. C-terminal: COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase; pfam02737, 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain. pfam00725, 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain (twice).; High confidence in function and specificity; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase 1884164 fadB 5174595 fadB Clavibacter michiganensis subsp. michiganensis NCPPB 382 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase YP_001222404.1 1882035 R 443906 CDS YP_001222405.1 148272844 5175369 complement(1884161..1885369) 1 NC_009480.1 putative 3-oxoacyl-CoA thiolase (NP_823409.1| putative 3-oxoacyl-CoA thiolase [Streptomyces avermitilis MA-4680]; ZP_00294151.1| COG0183: Acetyl-CoA acetyltransferase [Thermobifida fusca]). pfam00108,Thiolase_N, Thiolase, N-terminal domain. pfam02803,Thiolase_C, Thiolase, C-terminal domain.; High confidence in function and specificity; putative 3-oxoacyl-CoA thiolase 1885369 fadA 5175369 fadA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 3-oxoacyl-CoA thiolase YP_001222405.1 1884161 R 443906 CDS YP_001222406.1 148272845 5173854 complement(1885441..1886931) 1 NC_009480.1 putative Ribonuclease D (NP_630139.1| putative ribonuclease [Streptomyces coelicolor A3(2)]; ZP_00294153.1| COG0349: Ribonuclease D [Thermobifida fusca]). InterPro: 3-5 exonuclease. pfam01612, 3_5_exonuc,3'-5' exonuclease. pfam00570, HRDC, HRDC domain. The HRDC (Helicase and RNase D C-terminal) domain has a putative role in nucleic acid binding.; Specificity unclear; putative ribonuclease D 1886931 5173854 CMM_1663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ribonuclease D YP_001222406.1 1885441 R 443906 CDS YP_001222407.1 148272846 5172920 complement(1886928..1887524) 1 NC_009480.1 conserved hypothetical protein (ZP_00226661.1| hypothetical protein Krad06002913 [Kineococcus radiotolerans SRS30216]; NP_630141.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 1887524 5172920 CMM_1664 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222407.1 1886928 R 443906 CDS YP_001222408.1 148272847 5172965 complement(1887619..1888365) 1 NC_009480.1 putative pyrimidine reductase (NP_787520.1| 5-amino-6-(5-phospho- ribosylamino)uracil reductase [Tropheryma whipplei str. Twist]; ZP_00292785.1| COG1985: Pyrimidine reductase, riboflavin biosynthesis [Thermobifida fusca]). pfam01872, RibD_C, RibD C-terminal domain.; Function unclear; putative pyrimidine reductase 1888365 5172965 CMM_1665 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyrimidine reductase YP_001222408.1 1887619 R 443906 CDS YP_001222409.1 148272848 5172984 complement(1888362..1888802) 1 NC_009480.1 conserved protein putatively involved in Fe-S assembly (ZP_00228362.1| COG2166: SufE protein probably involved in Fe-S center assembly [Kineococcus radiotolerans SRS30216]; CAB07067.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). InterPro: UPF0050_DUF pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export.; Function unclear; hypothetical protein 1888802 5172984 CMM_1666 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222409.1 1888362 R 443906 CDS YP_001222410.1 148272849 5172995 complement(1888799..1889710) 1 NC_009480.1 Thiosulfate sulfurtransferase (ZP_00228363.1| COG2897: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]; P96888|THT2_MYCTU Putative thiosulfate sulfurtransferase SSEA). pfam00581, Rhodanese,Rhodanese-like domain. Rhodanese has an internal duplication.; High confidence in function and specificity; thiosulfate sulfurtransferase 1889710 sseA 5172995 sseA Clavibacter michiganensis subsp. michiganensis NCPPB 382 thiosulfate sulfurtransferase YP_001222410.1 1888799 R 443906 CDS YP_001222411.1 148272850 5175927 1889879..1890943 1 NC_009480.1 putative ATPase (NP_823384.1| putative ATP/GTP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00228364.1| COG1485: Predicted ATPase [Kineococcus radiotolerans SRS30216]). pfam03969, AFG1_ATPase, AFG1-like ATPase. This family of proteins contains a P-loop motif and are predicted to be ATPases.; Function unclear; putative ATPase 1890943 5175927 CMM_1668 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001222411.1 1889879 D 443906 CDS YP_001222412.1 148272851 5173016 1891196..1892482 1 NC_009480.1 putative ammonium transporter, Amt family (ZP_00225603.1| COG0004: Ammonia permease [Kineococcus radiotolerans SRS30216]; Q10968|AMT_MYCTU Probable ammonium transporter)., , pfam00909, Ammonium_transp,Ammonium Transporter Family.; High confidence in function and specificity; ammonium transporter 1892482 amtB 5173016 amtB Clavibacter michiganensis subsp. michiganensis NCPPB 382 ammonium transporter YP_001222412.1 1891196 D 443906 CDS YP_001222413.1 148272852 5174820 1892731..1893570 1 NC_009480.1 putative aldo/keto-reductase (NP_823025.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]; BAB99752.1| Aldo/keto reductases, related to diketogulonate reductase [Corynebacterium glutamicum ATCC 13032]). InterPro: Aldo/keto reductase family pfam00248,Aldo_ket_red, Aldo/keto reductase family.; Function unclear; oxidoreductase 1893570 5174820 CMM_1670 Clavibacter michiganensis subsp. michiganensis NCPPB 382 oxidoreductase YP_001222413.1 1892731 D 443906 CDS YP_001222414.1 148272853 5173064 1893777..1894208 1 NC_009480.1 hypothetical protein (only weak match to putative transcriptional regulator (NP_784581.1| transcription regulator [Lactobacillus plantarum WCFS1]).; hypothetical protein 1894208 5173064 CMM_1671 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222414.1 1893777 D 443906 CDS YP_001222415.1 148272854 5173086 1894205..1895071 1 NC_009480.1 putative methyltransferase, HemK family (NP_822468.1| putative methytransferase [Streptomyces avermitilis MA-4680]; ZP_00225817.1| COG2890: Methylase of polypeptide chain release factors [Kineococcus radiotolerans SRS30216]). TIGRFam: hemK_fam: modification methylase, HemK; Function unclear; putative methyltransferase 1895071 5173086 CMM_1672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001222415.1 1894205 D 443906 CDS YP_001222416.1 148272855 5173142 1895220..1896515 1 NC_009480.1 Endo-1,4-beta-xylanase precursor (ZP_00191610.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; NP_242986.1| alkaline xylanase A (1,4-beta-D-xylan xylanohydrolase) [Bacillus halodurans C-125]). pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.; High confidence in function and specificity; endo-1,4-beta-xylanase A 1896515 xysA 5173142 xysA Clavibacter michiganensis subsp. michiganensis NCPPB 382 endo-1,4-beta-xylanase A YP_001222416.1 1895220 D 443906 CDS YP_001222417.1 148272856 5174317 1896686..1898695 1 NC_009480.1 Endo-14-beta-xylanase precursor (ZP_00191610.3| COG3693: Beta-1,4-xylanase [Kineococcus radiotolerans SRS30216]; T30910 xylanase (EC 3.2.1.-) - Caldocellum saccharolyticum). pfam02018, CBM_4_9, Carbohydrate binding domain. pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10. pfam02494, HYR, HYR domain.; High confidence in function and specificity; endo-1,4-beta-xylanase A 1898695 xysB 5174317 xysB Clavibacter michiganensis subsp. michiganensis NCPPB 382 endo-1,4-beta-xylanase A YP_001222417.1 1896686 D 443906 CDS YP_001222418.1 148272857 5174350 complement(1899661..1900137) 1 NC_009480.1 hypothetical protein 1900137 5174350 CMM_1675 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222418.1 1899661 R 443906 CDS YP_001222419.1 148272858 5173092 1900245..1900733 1 NC_009480.1 hypothetical protein 1900733 5173092 CMM_1676 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222419.1 1900245 D 443906 CDS YP_001222420.1 148272859 5173107 1900871..1901752 1 NC_009480.1 conserved hypothetical protein (NP_721208.1| conserved hypothetical protein [Streptococcus mutans UA159]; ZP_00056756.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]).; Function unclear; hypothetical protein 1901752 5173107 CMM_1677 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222420.1 1900871 D 443906 CDS YP_001222421.1 148272860 5173146 complement(1901811..1902281) 1 NC_009480.1 conserved hypothetical protein (ZP_00096355.1| COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes [Novosphingobium aromaticivorans]; NP_629734.1| conserved hypothetical protein SC2E1.17 [Streptomyces coelicolor A3(2)]). pfam00293, NUDIX, NUDIX domain. mutt: mutator mutT protein; Function unclear; putative mutT-like protein 1902281 5173146 CMM_1678 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mutT-like protein YP_001222421.1 1901811 R 443906 CDS YP_001222422.1 148272861 5173180 complement(1902278..1904365) 1 NC_009480.1 conserved hypothetical protein, ; NP_924649.1| probable peptidase [Gloeobacter violaceus]). pfam01738,DLH, Dienelactone hydrolase family.; Family membership; hypothetical protein 1904365 5173180 CMM_1679 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222422.1 1902278 R 443906 CDS YP_001222423.1 148272862 5173192 complement(1904405..1905184) 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (ZP_00228097.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_789380.1| putative oxidoreductase [Tropheryma whipplei TW08/27]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; short chain dehydrogenase 1905184 5173192 CMM_1680 Clavibacter michiganensis subsp. michiganensis NCPPB 382 short chain dehydrogenase YP_001222423.1 1904405 R 443906 CDS YP_001222424.1 148272863 5173209 1905363..1905680 1 NC_009480.1 hypothetical protein 1905680 5173209 CMM_1681 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222424.1 1905363 D 443906 CDS YP_001222425.1 148272864 5173266 1905677..1906465 1 NC_009480.1 putative glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) (ZP_00225962.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Kineococcus radiotolerans SRS30216]; CAB09602.1| POSSIBLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE [Mycobacterium tuberculosis H37Rv]; NP_828103.1| putative glycerophosphoryl diester phosphodiesterase [Streptomyces avermitilis MA-4680]). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. InterPro: Glycerophosphoryl diester phosphodiesterase pfam03009,GDPD, Glycerophosphoryl diester phosphodiesterase family. E. coli has two sequence related isozymes of glycerophosphoryl diester phosphodiesterase (GDPD) -periplasmic and cytosolic. This family also includes agrocinopine synthase, the similarity to GDPD has been noted. This family appears to have weak but not significant matches to mammalian phospholipase C pfam00388, which suggests that this family may adopt a TIM barrel fold.; Specificity unclear; putative glycerophosphoryl diester phosphodiesterase 1906465 glpQ2 5173266 glpQ2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerophosphoryl diester phosphodiesterase YP_001222425.1 1905677 D 443906 CDS YP_001222426.1 148272865 5173798 1906526..1906891 1 NC_009480.1 conserved hypothetical protein (CAF21487.1| putative membrane-associated GTPase [Corynebacterium glutamicum ATCC 13032]; NP_216566.1| hypothetical protein Rv2050 [Mycobacterium tuberculosis H37Rv]).; hypothetical protein 1906891 5173798 CMM_1683 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222426.1 1906526 D 443906 CDS YP_001222427.1 148272866 5173288 complement(1906979..1908520) 1 NC_009480.1 putative apolipoprotein N-acyltransferase 1908520 5173288 CMM_1684 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative apolipoprotein N-acyltransferase YP_001222427.1 1906979 R 443906 CDS YP_001222428.1 148272867 5173303 complement(1908562..1911033) 1 NC_009480.1 putative helicase (NP_695922.1| probable helicase [Bifidobacterium longum NCC2705]; NP_625906.1| putative helicase [Streptomyces coelicolor A3(2)]). pfam00270,DEAD, DEAD/DEAH box helicase.; Family membership; putative helicase 1911033 5173303 CMM_1685 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative helicase YP_001222428.1 1908562 R 443906 CDS YP_001222429.1 148272868 5173322 complement(1911128..1911880) 1 NC_009480.1 Sec-independent twin-arginine protein translocase (ZP_00225800.1| COG0805: Sec-independent protein secretion pathway component TatC [Kineococcus radiotolerans SRS30216]; NP_787448.1| twin-arginine translocase TatC component [Tropheryma whipplei str. Twist]). pfam00902,TatC, Sec-independent protein translocase protein . The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane.; High confidence in function and specificity; Sec-independent twin-arginine protein translocase 1911880 tatC 5173322 tatC Clavibacter michiganensis subsp. michiganensis NCPPB 382 Sec-independent twin-arginine protein translocase YP_001222429.1 1911128 R 443906 CDS YP_001222430.1 148272869 5173213 complement(1911935..1912279) 1 NC_009480.1 sec-independent twin-arginine protein translocase protein (Q10703|TATA_MYCTU Sec-independent protein translocase protein tatA/E homolog; P72267|TATA_RHOER Sec-independent protein translocase protein tatA/E homolog). pfam02416, MttA_Hcf106, mttA/Hcf106 family. Members of this protein family are involved in a sec independent translocation mechanism.; High confidence in function and specificity; sec-independent twin-arginine protein translocase protein 1912279 tatA 5173213 tatA Clavibacter michiganensis subsp. michiganensis NCPPB 382 sec-independent twin-arginine protein translocase protein YP_001222430.1 1911935 R 443906 CDS YP_001222431.1 148272870 5175908 complement(1912477..1913466) 1 NC_009480.1 putative transcriptional regulator, DeoR family (ZP_00225803.1| COG2378: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; CAB04764.1| ORF11(1) [Rhodococcus erythropolis]).; Specificity unclear; DeoR family transcriptional regulator 1913466 5175908 CMM_1688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DeoR family transcriptional regulator YP_001222431.1 1912477 R 443906 CDS YP_001222432.1 148272871 5173367 complement(1913463..1914470) 1 NC_009480.1 putative transcriptional regulator (ZP_00225804.1| COG2378: Predicted transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_960766.1| hypothetical protein MAP1832c [Mycobacterium avium subsp. paratuberculosis str. k10]).; Specificity unclear; putative transcriptional regulator 1914470 5173367 CMM_1689 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001222432.1 1913463 R 443906 CDS YP_001222433.1 148272872 5173382 complement(1914519..1915562) 1 NC_009480.1 Putative peptidyl-prolyl cis-trans isomerase (NP_787447.1| putative FKBP-type peptidyl-prolyl cis-trans isomerase [Tropheryma whipplei str. Twist]; NP_827862.1| putative FK-506 binding protein, peptidyl-prolyl cis-trans isomerase [Streptomyces avermitilis MA-4680]). pfam00254,FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase.; Function unclear; putative peptidyl-prolyl cis-trans isomerase 1915562 5173382 CMM_1690 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidyl-prolyl cis-trans isomerase YP_001222433.1 1914519 R 443906 CDS YP_001222434.1 148272873 5173408 complement(1915624..1916688) 1 NC_009480.1 putative methyltransferase (NP_625926.1| conserved hypothetical protein SCI41.34c [Streptomyces coelicolor A3(2)]; ZP_00199185.2| COG2519: tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Kineococcus radiotolerans SRS30216]). pfam01135, PCMT,Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). TIGRFam: pimt: protein-L-isoaspartate O-methyltr; Function unclear; putative methyltransferase 1916688 5173408 CMM_1691 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001222434.1 1915624 R 443906 CDS YP_001222435.1 148272874 5173435 complement(1916685..1917380) 1 NC_009480.1 putative phosphatase (ZP_00047611.2| COG0637: Predicted phosphatase/phosphohexomutase [Magnetospirillum magnetotacticum]; ZP_00227166.1| COG0637: Predicted phosphatase/phosphohexomutase [Kineococcus radiotolerans SRS30216]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative phosphatase 1917380 5173435 CMM_1692 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001222435.1 1916685 R 443906 CDS YP_001222436.1 148272875 5173452 1917473..1918432 1 NC_009480.1 conserved hypothetical protein (NP_625937.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00227165.1| hypothetical protein Krad06001765 [Kineococcus radiotolerans SRS30216]). pfam05601, DUF774,Protein of unknown function (DUF774). This family consists of several uncharacterised Actinomycete proteins of unknown function.; Family membership; hypothetical protein 1918432 5173452 CMM_1693 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222436.1 1917473 D 443906 CDS YP_001222437.1 148272876 5173441 complement(1918448..1919728) 1 NC_009480.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 1919728 cysS2 5173441 cysS2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 cysteinyl-tRNA synthetase YP_001222437.1 1918448 R 443906 CDS YP_001222438.1 148272877 5173944 complement(1919733..1920551) 1 NC_009480.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 1920551 bacA 5173944 bacA Clavibacter michiganensis subsp. michiganensis NCPPB 382 undecaprenyl pyrophosphate phosphatase YP_001222438.1 1919733 R 443906 CDS YP_001222439.1 148272878 5174520 complement(1920594..1921904) 1 NC_009480.1 putative metallopeptidase, peptidase family M20A (ZP_00228596.1| COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Kineococcus radiotolerans SRS30216]; NP_625951.1| putative peptidase [Streptomyces coelicolor A3(2)]). pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; hypothetical protein 1921904 5174520 CMM_1696 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222439.1 1920594 R 443906 CDS YP_001222440.1 148272879 5173053 1922243..1923259 1 NC_009480.1 putative magnesium and cobalt transporter, MIT family (ZP_00226389.1| COG0598: Mg2+ and Co2+ transporters [Kineococcus radiotolerans SRS30216]; ZP_00292887.1| COG0598: Mg2+ and Co2+ transporters [Thermobifida fusca]). , pfam01544, CorA, CorA-like Mg2+ transporter protein.,InterPro: Magnesium and cobalt transport protein CorA.; Specificity unclear; Mg2+/Co2+ transporter 1923259 corA1 5173053 corA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Mg2+/Co2+ transporter YP_001222440.1 1922243 D 443906 CDS YP_001222441.1 148272880 5173183 1923304..1924269 1 NC_009480.1 conserved hypothetical protein, putative UDP-glucose 4-epimerase (ZP_00227689.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; NP_107357.1| hypothetical protein mll6957 [Mesorhizobium loti MAFF303099]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative nucleoside-diphosphate-sugar epimerase 1924269 5173183 CMM_1698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001222441.1 1923304 D 443906 CDS YP_001222442.1 148272881 5173502 complement(1924278..1925618) 1 NC_009480.1 putative chaperone (NP_787408.1| chaperone protein [Tropheryma whipplei str. Twist]; NP_785551.1| chaperone protein DnaJ [Lactobacillus plantarum WCFS1]). pfam00226,DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system.; Function unclear; curved DNA binding protein 1925618 dnaJ3 5173502 dnaJ3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 curved DNA binding protein YP_001222442.1 1924278 R 443906 CDS YP_001222443.1 148272882 5173434 1925869..1926510 1 NC_009480.1 glycine betaine/carnitine/choline ABC transport system permease protein (NP_627156.1| putative permease membrane component [Streptomyces coelicolor A3(2)]; CAD91243.1| hypothetical protein [Nonomuraea sp. ATCC 39727]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; glycine betaine/carnitine/choline ABC transporter, permease component 1926510 5173434 CMM_1700 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycine betaine/carnitine/choline ABC transporter, permease component YP_001222443.1 1925869 D 443906 CDS YP_001222444.1 148272883 5173563 1926503..1927792 1 NC_009480.1 glycine betaine/carnitine/choline ABC transporter ATP-binding protein (NP_826323.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; NP_627157.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]). cd00267, ABC_ATPase, ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop andWalker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.; Specificity unclear; glycine betaine/carnitin ABC transporter ATP-binding protein 1927792 5173563 CMM_1701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycine betaine/carnitin ABC transporter ATP-binding protein YP_001222444.1 1926503 D 443906 CDS YP_001222445.1 148272884 5173582 1927789..1928556 1 NC_009480.1 putative glycine/betaine/choline ABC transporter,permease (NP_627158.1| putative permease membrane component [Streptomyces coelicolor A3(2)]; CAD91241.1| hypothetical protein [Nonomuraea sp. ATCC 39727]); Specificity unclear; putative glycine/betaine/choline ABC transporter, permease 1928556 5173582 CMM_1702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycine/betaine/choline ABC transporter, permease YP_001222445.1 1927789 D 443906 CDS YP_001222446.1 148272885 5173610 1928559..1929566 1 NC_009480.1 putative glycine betaine/carnitine/choline ABC transporter, substrate-binding protein (Osmoprotectant-binding protein) (CAD91240.1| hypothetical protein [Nonomuraea sp. ATCC 39727]; NP_627159.1| putative permease binding-protein component [Streptomyces coelicolor A3(2)]). MEMBER OF A HIGH AFFINITY MULTICOMPONENT BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR GLYCINE, BETAINE, CARNITINE AND CHOLINE. pfam04069,OpuAC, Substrate binding domain of ABC-type glycine betaine transport system. Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX),histidine (HisX) and taurine (TauA).; Specificity unclear; putative glycine/betaine ABC transporter,substrate-binding protein 1929566 5173610 CMM_1703 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycine/betaine ABC transporter,substrate-binding protein YP_001222446.1 1928559 D 443906 CDS YP_001222447.1 148272886 5174107 complement(1929809..1931617) 1 NC_009480.1 putative helicase (NP_826317.1| hypothetical protein SAV5140 [Streptomyces avermitilis MA-4680]; ZP_00293999.1| COG1061: DNA or RNA helicases of superfamily II [Thermobifida fusca]). pfam00270, DEAD,DEAD/DEAH box helicase.; Specificity unclear; putative DNA or RNA helicase 1931617 5174107 CMM_1704 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA or RNA helicase YP_001222447.1 1929809 R 443906 CDS YP_001222448.1 148272887 5173650 complement(1931818..1933017) 1 NC_009480.1 putative acyl-CoA dehydrogenase (ZP_00281635.1| COG1960: Acyl-CoA dehydrogenases [Burkholderia fungorum LB400]; NP_396585.1| acyl-CoA dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam02771, Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain. pfam02770, Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain. pfam00441, Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain.; Specificity unclear; putative acyl-CoA dehydrogenase 1933017 5173650 CMM_1705 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA dehydrogenase YP_001222448.1 1931818 R 443906 CDS YP_001222449.1 148272888 5173671 complement(1933069..1933920) 1 NC_009480.1 conserved hypothetical protein (ZP_00209207.1| COG2514: Predicted ring-cleavage extradiol dioxygenase [Magnetospirillum magnetotacticum]; NP_738598.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). containing two domains of pfam00903, Glyoxalase,Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; Function unclear; hypothetical protein 1933920 5173671 CMM_1706 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222449.1 1933069 R 443906 CDS YP_001222450.1 148272889 5173753 1934046..1934837 1 NC_009480.1 putative esterase (ZP_00293606.1| COG2755: Lysophospholipase L1 and related esterases [Thermobifida fusca]; NP_822814.1| hypothetical protein SAV1638 [Streptomyces avermitilis MA-4680]). pfam00657,Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Function unclear; putative esterase 1934837 5173753 CMM_1707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001222450.1 1934046 D 443906 CDS YP_001222451.1 148272890 5173788 complement(1934853..1936067) 1 NC_009480.1 putative D-alanyl-D-alanine carboxypeptidase (Penicillin-binding protein) (NP_787455.1| serine-type D-Ala-D-Ala carboxypeptidase [Tropheryma whipplei str. Twist]; AAC32488.1| penicillin binding protein PbpA [Streptomyces clavuligerus]). , pfam00768, Peptidase_S11,D-alanyl-D-alanine carboxypeptidase.; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase 1936067 pbpX 5173788 pbpX Clavibacter michiganensis subsp. michiganensis NCPPB 382 D-alanyl-D-alanine carboxypeptidase YP_001222451.1 1934853 R 443906 CDS YP_001222452.1 148272891 5175525 complement(1936064..1936873) 1 NC_009480.1 putative rRNA methylase (NP_696042.1| possible tRNA/rRNA methyltransferase [Bifidobacterium longum NCC2705]; NP_827973.1| putative rRNA methylase [Streptomyces avermitilis MA-4680]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet.; Specificity unclear; hypothetical protein 1936873 5175525 CMM_1709 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222452.1 1936064 R 443906 CDS YP_001222453.1 148272892 5173807 1937030..1937884 1 NC_009480.1 putative NAD-dependent deacetylase, SIR2 family regulatory protein (NP_961194.1| hypothetical protein MAP2260 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_821712.1| putative Sir2-family regulator protein [Streptomyces avermitilis MA-4680]). Modulates the activities of several enzymes which are inactive in their acetylated form. pfam02146, SIR2, Sir2 family.; Specificity unclear; Sir2 family NAD-dependent protein deacetylase 1937884 5173807 CMM_1710 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Sir2 family NAD-dependent protein deacetylase YP_001222453.1 1937030 D 443906 CDS YP_001222454.1 148272893 5173875 1937881..1938516 1 NC_009480.1 putative phosphoglycerate mutase (ZP_00272306.1| COG0406: Fructose-2,6-bisphosphatase [Ralstonia metallidurans CH34]; ZP_00189764.2| COG0406: Fructose-2,6- bisphosphatase [Kineococcus radiotolerans SRS30216]). pfam00300, PGAM, Phosphoglycerate mutase family.; Specificity unclear; phosphoglycerate mutase 1938516 5173875 CMM_1711 Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglycerate mutase YP_001222454.1 1937881 D 443906 CDS YP_001222455.1 148272894 5173953 complement(1938570..1939664) 1 NC_009480.1 putative mannosyltransferase, glycosyl transferase family 1 (NP_780975.1| mannosyltransferase [Clostridium tetani E88]; NP_254135.1| glycosyltransferase WbpY [Pseudomonas aeruginosa PA01]). pfam00534,Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer UDP, ADP, GDP or CMP linked sugars.; Specificity unclear; glycosyl transferase family protein 1939664 5173953 CMM_1712 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycosyl transferase family protein YP_001222455.1 1938570 R 443906 CDS YP_001222456.1 148272895 5173980 complement(1939661..1940557) 1 NC_009480.1 putative hydrolase (NP_249520.1| probable hydrolase [Pseudomonas aeruginosa PA01]; NP_824268.1| putative hydrolase [Streptomyces avermitilis MA-4680]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative hydrolase 1940557 5173980 CMM_1713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001222456.1 1939661 R 443906 CDS YP_001222457.1 148272896 5173964 1940695..1942416 1 NC_009480.1 putative trehalose synthase (Maltose alpha-D-glucosyltransferase) (ZP_00228506.1| COG0366: Glycosidases [Kineococcus radiotolerans SRS30216]; NP_823979.1| putative trehalose synthase [Streptomyces avermitilis MA-4680]). pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative trehalose synthase 1942416 5173964 CMM_1714 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative trehalose synthase YP_001222457.1 1940695 D 443906 CDS YP_001222458.1 148272897 5174034 1942427..1943128 1 NC_009480.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1943128 dnaQ 5174034 dnaQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III subunit epsilon YP_001222458.1 1942427 D 443906 CDS YP_001222459.1 148272898 5174780 complement(1943205..1943462) 1 NC_009480.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 1943462 rpmE2 5174780 rpmE2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L31 type B YP_001222459.1 1943205 R 443906 CDS YP_001222460.1 148272899 5174182 complement(1943594..1944388) 1 NC_009480.1 putative molybdate ABC transporter ATP-binding protein (NP_827656.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00192057.2| COG1119: ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative molybdate ABC transporter ATP-binding subunit 1944388 modF 5174182 modF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdate ABC transporter ATP-binding subunit YP_001222460.1 1943594 R 443906 CDS YP_001222461.1 148272900 5175376 complement(1944470..1945654) 1 NC_009480.1 putative glycosyl transferase (ZP_00228927.1| COG0438: Glycosyltransferase [Kineococcus radiotolerans SRS30216]; ZP_00120280.2| COG0438: Glycosyltransferase [Bifidobacterium longum DJO10A]). InterPro: Glycosyl transferases group 1 pfam00534, Glycos_transf_1, Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase 1945654 5175376 CMM_1718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001222461.1 1944470 R 443906 CDS YP_001222462.1 148272901 5174018 1945701..1946942 1 NC_009480.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 1946942 glgC 5174018 glgC Clavibacter michiganensis subsp. michiganensis NCPPB 382 glucose-1-phosphate adenylyltransferase YP_001222462.1 1945701 D 443906 CDS YP_001222463.1 148272902 5173169 1946939..1947637 1 NC_009480.1 putative phosphoserine phosphatase (O-phosphoserine phosphohydrolase) (NP_696939.1| probable phosphoserine phosphatase [Bifidobacterium longum NCC2705]; ZP_00209254.1| COG0560: Phosphoserine phosphatase [Magnetospirillum magnetotacticum]). pfam00702, Hydrolase,haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. serB: phosphoserine phosphatase SerB.; Specificity unclear; hypothetical protein 1947637 serB2 5173169 serB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222463.1 1946939 D 443906 CDS YP_001222464.1 148272903 5174218 complement(1947658..1948614) 1 NC_009480.1 putative proteinkinase or phosphotransferase (ZP_00238793.1| putative protein kinase [Bacillus cereus G9241]; ZP_00305365.1| COG3173: Predicted aminoglycoside phosphotransferase [Novosphingobium aromaticivorans DSM 12444]). pfam01636, APH, Phosphotransferase enzyme family.; Function unclear; putative proteinkinase or phosphotransferase 1948614 5174218 CMM_1721 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative proteinkinase or phosphotransferase YP_001222464.1 1947658 R 443906 CDS YP_001222465.1 148272904 5174087 complement(1948638..1949348) 1 NC_009480.1 putative 3-oxoacyl-[acyl-carrier protein] reductase (ZP_00059542.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Thermobifida fusca]; NP_626084.1| probable 3-oxacyl-(acyl-carrier-protein) reductase [Streptomyces coelicolor A3(2)] ). pfam00106, adh_short,short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative 3-oxoacyl-[acyl-carrier protein] reductase 1949348 5174087 CMM_1722 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 3-oxoacyl-[acyl-carrier protein] reductase YP_001222465.1 1948638 R 443906 CDS YP_001222466.1 148272905 5174104 1949468..1949923 1 NC_009480.1 hypothetical protein (ZP_00228932.1| hypothetical protein Krad06000613 [Kineococcus radiotolerans SRS30216]; NP_827633.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 1949923 5174104 CMM_1723 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222466.1 1949468 D 443906 CDS YP_001222467.1 148272906 5174251 1949920..1950177 1 NC_009480.1 conserved hypothetical protein (YP_062125.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827632.1| hypothetical protein SAV6456 [Streptomyces avermitilis MA-4680]).; hypothetical protein 1950177 5174251 CMM_1724 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222467.1 1949920 D 443906 CDS YP_001222468.1 148272907 5174294 1950174..1951019 1 NC_009480.1 conserved membrane protein (ZP_00228934.1| COG3346: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; NP_302130.1| conserved membrane protein [Mycobacterium leprae TN]).; Conserved hypothetical protein; hypothetical protein 1951019 5174294 CMM_1725 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222468.1 1950174 D 443906 CDS YP_001222469.1 148272908 5174306 complement(1951025..1952623) 1 NC_009480.1 putative ABC transporter ATP-binding protein (ZP_00228938.1| COG0488: ATPase components of ABC transporters with duplicated ATPase domains [Kineococcus radiotolerans SRS30216]; NP_827602.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]). InterPro: AAA ATPase superfamily pfam00005,ABC_tran, ABC transporter (twice).; Function unclear; putative ABC transporter ATP-binding protein 1952623 5174306 CMM_1726 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter ATP-binding protein YP_001222469.1 1951025 R 443906 CDS YP_001222470.1 148272909 5174389 complement(1952848..1953183) 1 NC_009480.1 conserved hypothetical protein (ZP_00228941.1| COG2151: Predicted metal-sulfur cluster biosynthetic enzyme [Kineococcus radiotolerans SRS30216]; NP_827507.1| hypothetical protein SAV6331 [Streptomyces avermitilis MA-4680]). pfam01883, DUF59, Domain of unknown function DUF59.; Function unclear; hypothetical protein 1953183 5174389 CMM_1727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222470.1 1952848 R 443906 CDS YP_001222471.1 148272910 5174413 complement(1953180..1953950) 1 NC_009480.1 putative ABC transporter, ATP-binding protein,putatively involved in Fe-S cluster assembly (YP_062121.1| multidrug Resistance Exporter [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228942.1| COG0396: ABC-type transport system involved in Fe-S cluster assembly, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter. InterPro: ABC transporter.; Function unclear; putative ABC transporter, ATP-binding protein 1953950 5174413 CMM_1728 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001222471.1 1953180 R 443906 CDS YP_001222472.1 148272911 5174463 complement(1953964..1954284) 1 NC_009480.1 putative 2Fe-2S ferredoxin (YP_062120.1| benzene 1,2-dioxygenase, ferredoxin protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787463.1| dioxygenase ferredoxin subunit [Tropheryma whipplei str. Twist]). pfam00355,Rieske, Rieske [2Fe-2S] domain. The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines. InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Specificity unclear; putative 2Fe-2S ferredoxin 1954284 5174463 CMM_1729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2Fe-2S ferredoxin YP_001222472.1 1953964 R 443906 CDS YP_001222473.1 148272912 5174499 complement(1954281..1955504) 1 NC_009480.1 conserved hypothetical protein (YP_062119.1| ABC transporter, membrane component [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827502.1| hypothetical protein SAV6326 [Streptomyces avermitilis MA-4680]). pfam01458,UPF0051, Uncharacterized protein family (UPF0051).; hypothetical protein 1955504 5174499 CMM_1730 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222473.1 1954281 R 443906 CDS YP_001222474.1 148272913 5175317 complement(1955505..1956923) 1 NC_009480.1 conserved hypothetical protein (NP_626190.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00228944.1| COG0719: ABC-type transport system involved in Fe-S cluster assembly, permease component [Kineococcus radiotolerans SRS30216]). pfam01458, UPF0051,Uncharacterized protein family (UPF0051). InterPro: Uncharacterized protein family UPF0051.; hypothetical protein 1956923 5175317 CMM_1731 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222474.1 1955505 R 443906 CDS YP_001222475.1 148272914 5174541 1957190..1958200 1 NC_009480.1 conserved membrane protein, putative cytochrome oxidase assembly protein (YP_062117.1| cytochrome oxidase assembly protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789364.1| putative cytochrome synthase [Tropheryma whipplei TW08/27]). , pfam02628, COX15-CtaA,Cytochrome oxidase assembly protein. This is a family of integral membrane proteins.; High confidence in function and specificity; membrane protein, putative cytochrome oxidase assembly protein 1958200 ctaA 5174541 ctaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative cytochrome oxidase assembly protein YP_001222475.1 1957190 D 443906 CDS YP_001222476.1 148272915 5175889 complement(1958420..1959340) 1 NC_009480.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1959340 ctaB 5175889 ctaB Clavibacter michiganensis subsp. michiganensis NCPPB 382 protoheme IX farnesyltransferase YP_001222476.1 1958420 R 443906 CDS YP_001222477.1 148272916 5174267 1959514..1961604 1 NC_009480.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1961604 tktA 5174267 tktA Clavibacter michiganensis subsp. michiganensis NCPPB 382 transketolase YP_001222477.1 1959514 D 443906 CDS YP_001222478.1 148272917 5175888 1961759..1962874 1 NC_009480.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate; transaldolase 1962874 talA 5175888 talA Clavibacter michiganensis subsp. michiganensis NCPPB 382 transaldolase YP_001222478.1 1961759 D 443906 CDS YP_001222479.1 148272918 5175855 1962871..1964466 1 NC_009480.1 putative glucose-6-phosphate isomerase (Phosphoglucose isomerase)(Phosphohexose isomerase) (YP_062113.1| glucose-6-phosphate isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789360.1| glucose-6-phosphate isomerase [Tropheryma whipplei TW08/27]). pfam00342, PGI, Phosphoglucose isomerase. Phosphoglucose isomerase catalyses the interconversion of glucose-6-phosphate and fructose-6-phosphate.; High confidence in function and specificity; hypothetical protein 1964466 pgiA 5175855 pgiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222479.1 1962871 D 443906 CDS YP_001222480.1 148272919 5174825 1964505..1966046 1 NC_009480.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1966046 zwfA2 5174825 zwfA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glucose-6-phosphate 1-dehydrogenase YP_001222480.1 1964505 D 443906 CDS YP_001222481.1 148272920 5173887 1966043..1967041 1 NC_009480.1 putative glucose-6-P dehydrogenase effector (YP_062111.1| oxppcycle protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228950.1| COG3429: Glucose-6-P dehydrogenase subunit [Kineococcus radiotolerans SRS30216]).; High confidence in function and specificity; putative glucose-6-P dehydrogenase effector 1967041 opcA 5173887 opcA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucose-6-P dehydrogenase effector YP_001222481.1 1966043 D 443906 CDS YP_001222482.1 148272921 5175651 1967038..1967808 1 NC_009480.1 putative 6-phosphogluconolactonase (ZP_00294052.1| COG0363: 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Thermobifida fusca]; Q9XAB7|6PGL_STRCO 6-phosphogluconolactonase (6PGL)). pfam01182, Glucosamine_iso, Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase.; High confidence in function and specificity; putative 6-phosphogluconolactonase 1967808 pglA 5175651 pglA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 6-phosphogluconolactonase YP_001222482.1 1967038 D 443906 CDS YP_001222483.1 148272922 5174784 complement(1968002..1968370) 1 NC_009480.1 putative electron transport protein (Rieske iron-sulfur protein) (YP_062109.1| electron transport protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827476.1| putative electron transport protein [Streptomyces avermitilis MA-4680]).; Function unclear; putative electron transport protein 1968370 5174784 CMM_1740 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative electron transport protein YP_001222483.1 1968002 R 443906 CDS YP_001222484.1 148272923 5174674 complement(1968382..1968633) 1 NC_009480.1 putative protein-export membrane protein (YP_062108.1| protein-export membrane protein SecG [Leifsonia xyli subsp. xyli str. CTCB07]; NP_695892.1| protein- export membrane protein SecG [Bifidobacterium longum NCC2705]; AAG16895.1| SecG [Streptomyces lividans]). pfam03840, SecG, Preprotein translocase SecG subunit.; Conserved hypothetical protein; preprotein translocase subunit SecG 1968633 secG 5174674 secG Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecG YP_001222484.1 1968382 R 443906 CDS YP_001222485.1 148272924 5175020 complement(1968777..1969574) 1 NC_009480.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1969574 tpiA 5175020 tpiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 triosephosphate isomerase YP_001222485.1 1968777 R 443906 CDS YP_001222486.1 148272925 5175555 complement(1969571..1970785) 1 NC_009480.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1970785 pgk 5175555 pgk Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglycerate kinase YP_001222486.1 1969571 R 443906 CDS YP_001222487.1 148272926 5174718 complement(1970792..1971799) 1 NC_009480.1 putative glyceraldehyde 3-phosphate dehydrogenase (YP_062105.1| glyceraldehyde 3-phosphate dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228958.1| COG0057: Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Kineococcus radiotolerans SRS30216]). pfam00044, Gp_dh_N,Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain. GAPDH is a tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis. pfam02800, Gp_dh_C,Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain.; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 1971799 gapA 5174718 gapA Clavibacter michiganensis subsp. michiganensis NCPPB 382 glyceraldehyde 3-phosphate dehydrogenase YP_001222487.1 1970792 R 443906 CDS YP_001222488.1 148272927 5175066 complement(1971927..1972553) 1 NC_009480.1 superoxide dismutase [Mn/Fe] (YP_062104.1| superoxide dismutase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198450.2| COG0605: Superoxide dismutase [Kineococcus radiotolerans SRS30216]). , pfam00081,Sod_Fe_N, Iron/manganese superoxide dismutases, alpha-hairpin domain. , pfam02777, Sod_Fe_C, Iron/manganese superoxide dismutases, C-terminal domain. , InterPro: Manganese and iron superoxide dismutase (SODM); High confidence in function and specificity; hypothetical protein 1972553 sodA 5175066 sodA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222488.1 1971927 R 443906 CDS YP_001222489.1 148272928 5175710 complement(1972722..1973702) 1 NC_009480.1 conserved hypothetical protein, whiA homolog (YP_062103.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228959.1| COG1481: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_335917.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]). WhiA maybe a regulator which is essential for sporulation in Streptomyces pfam02650, DUF199,Uncharacterized BCR, COG1481.; Function unclear; hypothetical protein 1973702 whiA 5175710 whiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222489.1 1972722 R 443906 CDS YP_001222490.1 148272929 5173681 complement(1973732..1974607) 1 NC_009480.1 conserved hypothetical protein, putative kinase (YP_062102.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228961.1| COG1660: Predicted P-loop-containing kinase [Kineococcus radiotolerans SRS30216]; NP_626216.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam03668, ATP_bind_2, P-loop ATPase protein family.; Function unclear; hypothetical protein 1974607 5173681 CMM_1747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222490.1 1973732 R 443906 CDS YP_001222491.1 148272930 5174518 complement(1974683..1976611) 1 NC_009480.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1976611 uvrC 5174518 uvrC Clavibacter michiganensis subsp. michiganensis NCPPB 382 excinuclease ABC subunit C YP_001222491.1 1974683 R 443906 CDS YP_001222492.1 148272931 5175593 complement(1976611..1979532) 1 NC_009480.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1979532 uvrA 5175593 uvrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 excinuclease ABC subunit A YP_001222492.1 1976611 R 443906 CDS YP_001222493.1 148272932 5173808 complement(1979615..1981681) 1 NC_009480.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1981681 uvrB 5173808 uvrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 excinuclease ABC subunit B YP_001222493.1 1979615 R 443906 CDS YP_001222494.1 148272933 5173234 complement(1981691..1982305) 1 NC_009480.1 dephospho-CoA kinase (YP_062097.1| dephospho-CoA kinase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82A24|COAE_STRAW Dephospho-CoA kinase (Dephosphocoenzyme A kinase)). Catalyzes the phosphorylation of the 3-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity). pfam01121, CoaE, Dephospho-CoA kinase.; High confidence in function and specificity; hypothetical protein 1982305 coaE 5173234 coaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222494.1 1981691 R 443906 CDS YP_001222495.1 148272934 5173497 complement(1982392..1983846) 1 NC_009480.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1983846 rpsA 5173497 rpsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S1 YP_001222495.1 1982392 R 443906 CDS YP_001222496.1 148272935 5175747 complement(1984033..1985712) 1 NC_009480.1 conserved hypothetical protein (YP_062095.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226344.1| COG4805: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam05960, DUF885, Bacterial protein of unknown function (DUF885). This family consists of several hypothetical bacterial proteins several of which are putative membrane proteins.; Function unclear; hypothetical protein 1985712 5175747 CMM_1753 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222496.1 1984033 R 443906 CDS YP_001222497.1 148272936 5174651 complement(1985709..1986167) 1 NC_009480.1 PTS system, IIA component (YP_044170.1| PTS system,mannitol-specific IIA component [Staphylococcus aureus subsp. aureus MSSA476]; NP_244719.1| PTS system, mannitol-specific enzyme II, A component [Bacillus halodurans C-125]). , pfam00359, PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.; Specificity unclear; PTS system, fructose-specific IIA/fpr component 1986167 5174651 CMM_1754 Clavibacter michiganensis subsp. michiganensis NCPPB 382 PTS system, fructose-specific IIA/fpr component YP_001222497.1 1985709 R 443906 CDS YP_001222498.1 148272937 5174702 complement(1986210..1988894) 1 NC_009480.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1988894 polA1 5174702 polA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase I YP_001222498.1 1986210 R 443906 CDS YP_001222499.1 148272938 5173250 1988948..1989382 1 NC_009480.1 conserved hypothetical protein, putative thioesterase (ZP_00057601.1| COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism [Thermobifida fusca]; ZP_00227222.1| COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism [Kineococcus radiotolerans SRS30216]). pfam03061, 4HBT, Thioesterase superfamily. This family contains a wide variety of enzymes,principally thioesterases.; Function unclear; putative thioesterase 1989382 5173250 CMM_1756 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioesterase YP_001222499.1 1988948 D 443906 CDS YP_001222500.1 148272939 5174778 complement(1989422..1990030) 1 NC_009480.1 putative response regulator involved in antitermination (YP_062092.1| two-component system,regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291532.1| COG3707: Response regulator with putative antiterminator output domain [Thermobifida fusca]). cd00156, REC, Signal receiver domain. pfam03861,ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; Specificity unclear; putative response regulator involved in antitermination 1990030 5174778 CMM_1757 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative response regulator involved in antitermination YP_001222500.1 1989422 R 443906 CDS YP_001222501.1 148272940 5174900 complement(1990294..1991739) 1 NC_009480.1 pyruvate kinase (YP_062088.1| pyruvate kinase II [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225692.1| COG0469: Pyruvate kinase [Kineococcus radiotolerans SRS30216]). pfam00224, PK, Pyruvate kinase, barrel domain. pfam02887, PK_C, Pyruvate kinase, alpha/beta domain.; High confidence in function and specificity; hypothetical protein 1991739 pykA 5174900 pykA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222501.1 1990294 R 443906 CDS YP_001222502.1 148272941 5174454 complement(1991826..1993283) 1 NC_009480.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 1993283 gltD 5174454 gltD Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamate synthase subunit beta YP_001222502.1 1991826 R 443906 CDS YP_001222503.1 148272942 5174215 complement(1993276..1997847) 1 NC_009480.1 glutamate synthase (NADPH), alpha subunit (CAG18963.1| putative glutamate synthase, large subunit [Photobacterium profundum]; BAA75929.1| glutamine 2-oxoglutarate aminotransferase large subunit [Corynebacterium glutamicum]). pfam04897, Glu_synth_NTN,Glutamate synthase amidotransferase domain. pfam04898,Glu_syn_central, Glutamate synthase central domain. pfam01645, Glu_synthase, Conserved region in glutamate synthase. The aligned region of these proteins contains a putative FMN binding site and Fe-S cluster. pfam01493,GXGXG, GXGXG motif. InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity; glutamate synthase (NADPH), alpha subunit 1997847 gltB 5174215 gltB Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamate synthase (NADPH), alpha subunit YP_001222503.1 1993276 R 443906 CDS YP_001222504.1 148272943 5174995 complement(1997955..1998977) 1 NC_009480.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1998977 5174995 CMM_1761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 prolipoprotein diacylglyceryl transferase YP_001222504.1 1997955 R 443906 CDS YP_001222505.1 148272944 5174984 complement(1999049..1999861) 1 NC_009480.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1999861 trpA 5174984 trpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 tryptophan synthase subunit alpha YP_001222505.1 1999049 R 443906 CDS YP_001222506.1 148272945 5174329 complement(1999858..2001072) 1 NC_009480.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2001072 trpB 5174329 trpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 tryptophan synthase subunit beta YP_001222506.1 1999858 R 443906 CDS YP_001222507.1 148272946 5175347 complement(2001069..2001845) 1 NC_009480.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 2001845 trpC 5175347 trpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 indole-3-glycerol-phosphate synthase YP_001222507.1 2001069 R 443906 CDS YP_001222508.1 148272947 5174800 complement(2001845..2002087) 1 NC_009480.1 putative membrane protein (YP_062081.1| mambrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626301.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00226960.1| COG3125: Heme/copper-type cytochrome/quinol oxidase, subunit 4 [Kineococcus radiotolerans SRS30216]).; Hypothetical protein; hypothetical protein 2002087 5174800 CMM_1765 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222508.1 2001845 R 443906 CDS YP_001222509.1 148272948 5175165 complement(2002192..2002830) 1 NC_009480.1 conserved membrane protein (YP_062080.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226959.1| hypothetical protein Krad06002361 [Kineococcus radiotolerans SRS30216]; NP_827348.1| putative membrane protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 2002830 5175165 CMM_1766 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222509.1 2002192 R 443906 CDS YP_001222510.1 148272949 5174895 complement(2002830..2004389) 1 NC_009480.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 2004389 trpE1 5174895 trpE1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 anthranilate synthase component I YP_001222510.1 2002830 R 443906 CDS YP_001222511.1 148272950 5174907 complement(2004386..2004784) 1 NC_009480.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 2004784 hisI 5174907 hisI Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosyl-AMP cyclohydrolase YP_001222511.1 2004386 R 443906 CDS YP_001222512.1 148272951 5175146 complement(2004781..2005572) 1 NC_009480.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2005572 hisF 5175146 hisF Clavibacter michiganensis subsp. michiganensis NCPPB 382 imidazole glycerol phosphate synthase subunit HisF YP_001222512.1 2004781 R 443906 CDS YP_001222513.1 148272952 5173666 complement(2005575..2006414) 1 NC_009480.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2006414 hisG 5173666 hisG Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP phosphoribosyltransferase YP_001222513.1 2005575 R 443906 CDS YP_001222514.1 148272953 5174010 complement(2006463..2006726) 1 NC_009480.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2006726 hisE 5174010 hisE Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosyl-ATP pyrophosphatase YP_001222514.1 2006463 R 443906 CDS YP_001222515.1 148272954 5173657 complement(2006826..2007194) 1 NC_009480.1 putative peptidyl-prolyl cis-trans isomerase (AAF04134.1| FK506 binding protein [Mycobacterium smegmatis]; YP_061894.1| FKBP-type peptidyl-prolyl cis-trans isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_737516.1| putative peptidylprolyl isomerase [Corynebacterium efficiens YS-314]). PPIases accelerate the folding of proteins. pfam00254, FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase. InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) 2007194 5173657 CMM_1772 Clavibacter michiganensis subsp. michiganensis NCPPB 382 FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase) YP_001222515.1 2006826 R 443906 CDS YP_001222516.1 148272955 5175070 complement(2007229..2007897) 1 NC_009480.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 2007897 rpeA 5175070 rpeA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribulose-phosphate 3-epimerase YP_001222516.1 2007229 R 443906 CDS YP_001222517.1 148272956 5172977 complement(2007908..2009407) 1 NC_009480.1 putative rRNA cytosine-C5-methylase (SUN protein,FMU protein) (ZP_00057727.1| COG0144: tRNA and rRNA cytosine-C5-methylases [Thermobifida fusca]; ZP_00226945.1| COG0144: tRNA and rRNA cytosine-C5-methylases [Kineococcus radiotolerans SRS30216]). cd00620,Methyltransferase_Sun, N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. pfam01189,Nol1_Nop2_Sun, NOL1/NOP2/sun family.; Specificity unclear; putative rRNA cytosine-C5-methylases 2009407 5172977 CMM_1774 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative rRNA cytosine-C5-methylases YP_001222517.1 2007908 R 443906 CDS YP_001222518.1 148272957 5175100 complement(2009404..2010321) 1 NC_009480.1 methionyl-tRNA formyltransferase (YP_062073.1| methionyl-tRNA formyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291734.1| COG0223: Methionyl-tRNA formyltransferase [Thermobifida fusca]). Modify the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP. pfam00551, Formyl_trans_N, Formyl transferase. pfam02911, Formyl_trans_C, Formyl transferase, C-terminal domain. fmt: methionyl-tRNA formyltransferase; High confidence in function and specificity; hypothetical protein 2010321 fmtA 5175100 fmtA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222518.1 2009404 R 443906 CDS YP_001222519.1 148272958 5173538 complement(2010413..2012509) 1 NC_009480.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 2012509 priA 5173538 priA Clavibacter michiganensis subsp. michiganensis NCPPB 382 primosome assembly protein PriA YP_001222519.1 2010413 R 443906 CDS YP_001222520.1 148272959 5174516 complement(2012552..2013763) 1 NC_009480.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2013763 metK 5174516 metK Clavibacter michiganensis subsp. michiganensis NCPPB 382 S-adenosylmethionine synthetase YP_001222520.1 2012552 R 443906 CDS YP_001222521.1 148272960 5174232 complement(2013803..2015020) 1 NC_009480.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 2015020 dfpA 5174232 dfpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_001222521.1 2013803 R 443906 CDS YP_001222522.1 148272961 5174266 complement(2015099..2015368) 1 NC_009480.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2015368 rpoZ 5174266 rpoZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA-directed RNA polymerase subunit omega YP_001222522.1 2015099 R 443906 CDS YP_001222523.1 148272962 5174929 complement(2015417..2016325) 1 NC_009480.1 putative fusion protein guanylate kinase (GMP kinase)/integration host factor (IHF) (YP_062068.1| guanylate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787491.1| guanylate kinase; integration host factor fusion protein [Tropheryma whipplei str. Twist]; Q827Q3|KGUA_STRAW Guanylate kinase (GMP kinase)). Essential for recycling GMP and indirectly cGMP. pfam00625, Guanylate_kin, Guanylate kinase. InterPro: Guanylate kinase.; High confidence in function and specificity; putative guanylate kinase putative guanylate kinase (GMP kinase)/integration host factor (IHF) fusion protein 2016325 gmkA 5174929 gmkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative guanylate kinase putative guanylate kinase (GMP kinase)/integration host factor (IHF) fusion protein YP_001222523.1 2015417 R 443906 CDS YP_001222524.1 148272963 5175680 complement(2016322..2017215) 1 NC_009480.1 putative orotidine 5-phosphate decarboxylase (OMP decarboxylase) (YP_062067.1| orotidine 5'-phosphate decarboxylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226927.1| COG0284: Orotidine-5'- phosphate decarboxylase [Kineococcus radiotolerans SRS30216]). pfam00215, OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family.; High confidence in function and specificity; putative orotidine 5'-phosphate decarboxylase 2017215 pyrF 5175680 pyrF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative orotidine 5'-phosphate decarboxylase YP_001222524.1 2016322 R 443906 CDS YP_001222525.1 148272964 5174408 complement(2017212..2020502) 1 NC_009480.1 putative carbamoyl-phosphate synthase large subunit (CAG19020.1| putative carbamoylphosphate synthase large subunit [Photobacterium profundum]; AAB39256.1| carbamoylphosphate synthetase large subunit [Salmonella typhimurium]). pfam00289, CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain (twice). pfam02786, CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain (twice). pfam02787, CPSase_L_D3,Carbamoyl-phosphate synthetase large chain,oligomerisation domain. pfam02142, MGS, MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase and the domain is also found in Carbamoyl phosphate synthetase (CPS) where it forms a regulatory domain that binds to the allosteric effector ornithine.; High confidence in function and specificity; putative carbamoyl-phosphate synthase large subunit 2020502 carB 5174408 carB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carbamoyl-phosphate synthase large subunit YP_001222525.1 2017212 R 443906 CDS YP_001222526.1 148272965 5175950 complement(2020502..2021680) 1 NC_009480.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 2021680 carA 5175950 carA Clavibacter michiganensis subsp. michiganensis NCPPB 382 carbamoyl phosphate synthase small subunit YP_001222526.1 2020502 R 443906 CDS YP_001222527.1 148272966 5175045 complement(2021677..2022204) 1 NC_009480.1 conserved hypothetical protein (NP_625765.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; YP_062064.1| hypothetical protein Lxx11080 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2022204 5175045 CMM_1784 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222527.1 2021677 R 443906 CDS YP_001222528.1 148272967 5175183 complement(2022201..2023613) 1 NC_009480.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 2023613 pyrC 5175183 pyrC Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydroorotase YP_001222528.1 2022201 R 443906 CDS YP_001222529.1 148272968 5173363 complement(2023610..2024566) 1 NC_009480.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 2024566 pyrB 5173363 pyrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate carbamoyltransferase catalytic subunit YP_001222529.1 2023610 R 443906 CDS YP_001222530.1 148272969 5173722 complement(2024563..2025147) 1 NC_009480.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 2025147 pyrR 5173722 pyrR Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_001222530.1 2024563 R 443906 CDS YP_001222531.1 148272970 5174149 complement(2025260..2027296) 1 NC_009480.1 putative acetyl-coenzyme A synthetase (Acetate--CoA ligase) (ZP_00190335.3| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Kineococcus radiotolerans SRS30216]; ZP_00293126.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]; ACSA_STRAW Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme)). pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; acyl-coenzyme A synthetase 2027296 acsA2 5174149 acsA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 acyl-coenzyme A synthetase YP_001222531.1 2025260 R 443906 CDS YP_001222532.1 148272971 5173080 complement(2027371..2028234) 1 NC_009480.1 putative anion ABC transporter, permease component (ZP_00226717.1| COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00267258.1| COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Pseudomonas fluorescens PfO-1]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative anion ABC transporter, permease component 2028234 5173080 CMM_1789 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anion ABC transporter, permease component YP_001222532.1 2027371 R 443906 CDS YP_001222533.1 148272972 5175125 complement(2028231..2029283) 1 NC_009480.1 putative anion ABC transporter, substrate-binding protein (ZP_00226718.1| COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems,periplasmic components [Kineococcus radiotolerans SRS30216]; NP_959079.1| hypothetical protein MAP0145 [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Bacterial extracellular solute-binding proteins family 3.; Specificity unclear; putative anion ABC transporter, substrate-binding protein 2029283 5175125 CMM_1790 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anion ABC transporter, substrate-binding protein YP_001222533.1 2028231 R 443906 CDS YP_001222534.1 148272973 5175277 complement(2029356..2030225) 1 NC_009480.1 putative anion ABC transporter, ATP-binding protein (NP_959078.1| hypothetical protein MAP0145 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00226719.1| COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative anion ABC transporter, ATP-binding protein 2030225 5175277 CMM_1791 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anion ABC transporter, ATP-binding protein YP_001222534.1 2029356 R 443906 CDS YP_001222535.1 148272974 5175385 complement(2030333..2030746) 1 NC_009480.1 putative antitermination protein (ZP_00291753.1| COG0781: Transcription termination factor [Thermobifida fusca]; Q9KXR0|NUSB_STRCO N utilization substance protein B homolog (NusB protein)). pfam01029, NusB, NusB family. The NusB protein is involved in the regulation of rRNA biosynthesis by transcriptional antitermination. InterPro: Antitermination protein NusB; High confidence in function and specificity; putative antitermination protein 2030746 nusB 5175385 nusB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative antitermination protein YP_001222535.1 2030333 R 443906 CDS YP_001222536.1 148272975 5173872 complement(2030750..2031313) 1 NC_009480.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2031313 efpA 5173872 efpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 elongation factor P YP_001222536.1 2030750 R 443906 CDS YP_001222537.1 148272976 5175155 complement(2031425..2031865) 1 NC_009480.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2031865 aroQ 5175155 aroQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-dehydroquinate dehydratase YP_001222537.1 2031425 R 443906 CDS YP_001222538.1 148272977 5174639 complement(2031898..2032683) 1 NC_009480.1 putative short-chain dehydrogenase/reductase (ZP_00226581.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; NP_830063.1| 3-oxoacyl-[acyl-carrier protein] reductase [Bacillus cereus ATCC 14579]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short-chain dehydrogenase/reductase 2032683 5174639 CMM_1795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain dehydrogenase/reductase YP_001222538.1 2031898 R 443906 CDS YP_001222539.1 148272978 5175319 complement(2032680..2033813) 1 NC_009480.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 2033813 aroB 5175319 aroB Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-dehydroquinate synthase YP_001222539.1 2032680 R 443906 CDS YP_001222540.1 148272979 5173596 complement(2033810..2034301) 1 NC_009480.1 shikimate kinase (YP_062054.1| shikimate kinase I [Leifsonia xyli subsp. xyli str. CTCB07]; P95014|AROK_MYCTU Shikimate kinase (SK)). pfam01202, SKI,Shikimate kinase.; High confidence in function and specificity; hypothetical protein 2034301 aroK 5173596 aroK Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222540.1 2033810 R 443906 CDS YP_001222541.1 148272980 5175614 complement(2034304..2035542) 1 NC_009480.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2035542 aroC 5175614 aroC Clavibacter michiganensis subsp. michiganensis NCPPB 382 chorismate synthase YP_001222541.1 2034304 R 443906 CDS YP_001222542.1 148272981 5175766 complement(2035631..2036521) 1 NC_009480.1 Shikimate 5-dehydrogenase (YP_062052.1| shikimate 5-dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_301440.1| putative shikimate 5-dehydrogenase [Mycobacterium leprae TN]). pfam01488, Shikimate_DH,Shikimate / quinate 5-dehydrogenase. aroE: shikimate 5-dehydrogenase; High confidence in function and specificity; hypothetical protein 2036521 aroE 5175766 aroE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222542.1 2035631 R 443906 CDS YP_001222543.1 148272982 5174854 complement(2036514..2037659) 1 NC_009480.1 putative aminodeoxychorismate lyase (YP_055887.1| aminodeoxychorismate lyase [Propionibacterium acnes KPA171202]; NP_787502.1| hypothetical protein TWT374 [Tropheryma whipplei str. Twist]). pfam02618, ADC_lyase,Aminodeoxychorismate lyase. This family contains several aminodeoxychorismate lyase proteins. Aminodeoxychorismate lyase is a pyridoxal 5'-phosphate-dependent enzyme that converts 4-aminodeoxy- chorismate to pyruvate and p-aminobenzoate, a precursor of folic acid in bacteria.; Function unclear; hypothetical protein 2037659 5174854 CMM_1800 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222543.1 2036514 R 443906 CDS YP_001222544.1 148272983 5175315 complement(2038024..2038509) 1 NC_009480.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2038509 5175315 CMM_1801 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Holliday junction resolvase-like protein YP_001222544.1 2038024 R 443906 CDS YP_001222545.1 148272984 5175401 complement(2038509..2041166) 1 NC_009480.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2041166 alaS 5175401 alaS Clavibacter michiganensis subsp. michiganensis NCPPB 382 alanyl-tRNA synthetase YP_001222545.1 2038509 R 443906 CDS YP_001222546.1 148272985 5173606 complement(2041172..2041393) 1 NC_009480.1 hypothetical protein (YP_062048.1| Hypothetical protein Lxx10900 [Leifsonia xyli subsp. xyli str. CTCB07]; CAD47949.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein 2041393 5173606 CMM_1803 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222546.1 2041172 R 443906 CDS YP_001222547.1 148272986 5175862 complement(2041576..2042205) 1 NC_009480.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 2042205 rpsD 5175862 rpsD Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S4 YP_001222547.1 2041576 R 443906 CDS YP_001222548.1 148272987 5174270 complement(2042454..2043875) 1 NC_009480.1 putative ATPase (YP_062045.1| ATPase related to the helicase subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291928.1| COG2256: ATPase related to the helicase subunit of the Holliday junction resolvase [Thermobifida fusca]). pfam00004, AAA, ATPase family associated with various cellular activities (AAA).; Function unclear; recombination factor protein RarA 2043875 5174270 CMM_1805 Clavibacter michiganensis subsp. michiganensis NCPPB 382 recombination factor protein RarA YP_001222548.1 2042454 R 443906 CDS YP_001222549.1 148272988 5175796 2044467..2045699 1 NC_009480.1 conserved hypothetical protein, putative ATPase (YP_062043.1| ATPase involved in DNA repair [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828017.1| hypothetical protein SAV6841 [Streptomyces avermitilis MA-4680]; ZP_00057393.1| COG0419: ATPase involved in DNA repair [Thermobifida fusca]). pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins (twice).; Function unclear; putative ATPase 2045699 5175796 CMM_1807 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001222549.1 2044467 D 443906 CDS YP_001222550.1 148272989 5175746 2045793..2046401 1 NC_009480.1 hypothetical protein (YP_062042.1| Hypothetical protein Lxx10830 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121330.2| hypothetical protein Blon021233 [Bifidobacterium longum DJO10A]).; hypothetical protein 2046401 5175746 CMM_1808 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222550.1 2045793 D 443906 CDS YP_001222551.1 148272990 5175742 complement(2046388..2048637) 1 NC_009480.1 GTP pyrophosphokinase (ATP:GTP 3-pyrophosphotransferase) (ppGpp synthetase I) ((P)ppGpp synthetase) (YP_062041.1| GTP pyrophosphokinase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291937.1| COG0317: Guanosine polyphosphate pyrophosphohydrolases/ synthetases [Thermobifida fusca]). pfam01966, HD, HD domain. HD domains are metal dependent phosphohydrolases. pfam04607,RelA_SpoT, Region found in RelA / SpoT proteins. pfam02824, TGS, TGS domain. The TGS domain is named after ThrRS, GTPase, and SpoT. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. InterPro: RelA/SpoT family protein spoT_relA: RelA/SpoT family protein; High confidence in function and specificity; GTP pyrophosphokinase 2048637 relA 5175742 relA Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP pyrophosphokinase YP_001222551.1 2046388 R 443906 CDS YP_001222552.1 148272991 5174264 complement(2048776..2049135) 1 NC_009480.1 conserved hypothetical protein (YP_062040.1| thiosulfate sulfurtransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293320.1| COG0607: Rhodanese-related sulfurtransferase [Thermobifida fusca]). pfam00581,Rhodanese, Rhodanese-like domain.; Family membership; hypothetical protein 2049135 5174264 CMM_1810 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222552.1 2048776 R 443906 CDS YP_001222553.1 148272992 5175755 complement(2049132..2050142) 1 NC_009480.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 2050142 secF 5175755 secF Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecF YP_001222553.1 2049132 R 443906 CDS YP_001222554.1 148272993 5175477 complement(2050142..2051950) 1 NC_009480.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 2051950 secD 5175477 secD Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecD YP_001222554.1 2050142 R 443906 CDS YP_001222555.1 148272994 5174548 complement(2052077..2052460) 1 NC_009480.1 Region start changed from 2052547 to 2052460 (-87 bases); hypothetical protein 2052460 5174548 CMM_1813 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222555.1 2052077 R 443906 CDS YP_001222556.1 148272995 5175717 complement(2052537..2053616) 1 NC_009480.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2053616 ruvB 5175717 ruvB Clavibacter michiganensis subsp. michiganensis NCPPB 382 Holliday junction DNA helicase RuvB YP_001222556.1 2052537 R 443906 CDS YP_001222557.1 148272996 5174775 complement(2053613..2054257) 1 NC_009480.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2054257 ruvA 5174775 ruvA Clavibacter michiganensis subsp. michiganensis NCPPB 382 Holliday junction DNA helicase RuvA YP_001222557.1 2053613 R 443906 CDS YP_001222558.1 148272997 5173122 complement(2054274..2054882) 1 NC_009480.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2054882 ruvC 5173122 ruvC Clavibacter michiganensis subsp. michiganensis NCPPB 382 Holliday junction resolvase YP_001222558.1 2054274 R 443906 CDS YP_001222559.1 148272998 5174390 complement(2054934..2055701) 1 NC_009480.1 conserved hypothetical protein (YP_062033.1| Hypothetical protein Lxx10750 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057401.1| COG0217: Uncharacterized conserved protein [Thermobifida fusca]; CAB10838.1| HIGHLY CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01709, DUF28, Domain of unknown function DUF28. InterPro: Domain of unknown function DUF28.; Function unclear; hypothetical protein 2055701 5174390 CMM_1817 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222559.1 2054934 R 443906 CDS YP_001222560.1 148272999 5175677 complement(2055779..2056408) 1 NC_009480.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 2056408 5175677 CMM_1818 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glutamine amidotransferase subunit PdxT YP_001222560.1 2055779 R 443906 CDS YP_001222561.1 148273000 5173840 complement(2056398..2057300) 1 NC_009480.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 2057300 5173840 CMM_1819 Clavibacter michiganensis subsp. michiganensis NCPPB 382 pyridoxal biosynthesis lyase PdxS YP_001222561.1 2056398 R 443906 CDS YP_001222562.1 148273001 5175655 complement(2057314..2057856) 1 NC_009480.1 conserved hypothetical protein (YP_062028.1| Hypothetical protein Lxx10700 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827999.1| putative HIT family protein [Streptomyces avermitilis MA-4680]). pfam01230, HIT, HIT domain. InterPro: HIT (Histidine triad) family; Family membership; hypothetical protein 2057856 5175655 CMM_1820 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222562.1 2057314 R 443906 CDS YP_001222563.1 148273002 5175631 complement(2057901..2059955) 1 NC_009480.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 2059955 thrS 5175631 thrS Clavibacter michiganensis subsp. michiganensis NCPPB 382 threonyl-tRNA synthetase YP_001222563.1 2057901 R 443906 CDS YP_001222564.1 148273003 5174632 complement(2060771..2061730) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (YP_056970.1| transcriptional regulator [Propionibacterium acnes KPA171202]; P39140|DEOR_BACSU Deoxyribonucleoside regulator). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam04198, Sugar-bind, Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC.; Specificity unclear; Cro/CI family transcriptional regulator 2061730 5174632 CMM_1822 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001222564.1 2060771 R 443906 CDS YP_001222565.1 148273004 5175628 2061839..2063599 1 NC_009480.1 putative glycerol-3-phosphate dehydrogenase (NP_437021.1| putative glycerol-3-phosphate dehydrogenase protein [Sinorhizobium meliloti 1021]; NP_826180.1| putative glycerol-3-phosphate dehydrogenase [Streptomyces avermitilis MA-4680]). pfam01266, DAO, FAD dependent oxidoreductase. This family includes various FAD dependent oxidoreductases.; High confidence in function and specificity; putative glycerol-3-phosphate dehydrogenase 2063599 glpD 5175628 glpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerol-3-phosphate dehydrogenase YP_001222565.1 2061839 D 443906 CDS YP_001222566.1 148273005 5175213 2063716..2064207 1 NC_009480.1 putative peroxidase (ZP_00293036.1| COG0386: Glutathione peroxidase [Thermobifida fusca]; ZP_00228459.1| COG0386: Glutathione peroxidase [Kineococcus radiotolerans SRS30216]; AAO68877.1| putative glutathione peroxidase; vitamin B12 transport periplasmic protein BtuE [Salmonella enterica subsp. enterica serovar Typhi Ty2]). pfam00255, GSHPx,Glutathione peroxidase. InterPro: Glutathione peroxidase; Specificity unclear; putative peroxidase 2064207 5175213 CMM_1824 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peroxidase YP_001222566.1 2063716 D 443906 CDS YP_001222567.1 148273006 5175621 complement(2064253..2064768) 1 NC_009480.1 conserved hypothetical protein (ZP_00226621.1| hypothetical protein Krad06003015 [Kineococcus radiotolerans SRS30216]; NP_631325.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 2064768 5175621 CMM_1825 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222567.1 2064253 R 443906 CDS YP_001222568.1 148273007 5173867 2064860..2065276 1 NC_009480.1 conserved hypothetical protein (YP_062570.1| Hypothetical protein Lxx17000 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198676.1| COG3012: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam02810, SEC-C, SEC-C motif. The SEC-C motif found in the C-terminus of the SecA protein, in the middle of some SWI2 ATPases and also solo in several proteins. The motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain. InterPro: SEC-C motif; hypothetical protein 2065276 5173867 CMM_1826 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222568.1 2064860 D 443906 CDS YP_001222569.1 148273008 5175590 complement(2065310..2066044) 1 NC_009480.1 putative PTS system hybrid protein (YP_061966.1| PTS system enzyme I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_415716.1| PTS hybrid protein; putative PTS family enzyme I and HPr components [Escherichia coli K12]). , , pfam03610, EIIA-man, PTS system fructose IIA component (N-terminal). , pfam00381, PTS-HPr, PTS HPr component phosphorylation site (C-terminal)., COG1925,FruB, Phosphotransferase system, HPr-related proteins (C-terminal)., InterPro: Phosphocarrier HPr protein , EIIA-man: PTS system fructose subfamil; Conserved hypothetical protein; putative PTS system hybrid protein 2066044 5175590 CMM_1827 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative PTS system hybrid protein YP_001222569.1 2065310 R 443906 CDS YP_001222570.1 148273009 5175596 complement(2066041..2066694) 1 NC_009480.1 putative dihydroxyacetone kinase (YP_061965.1| dihydroxyacetone kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_782355.1| dihydroxyacetone kinase [Clostridium tetani E88]) pfam02734, Dak2, DAK2 domain. This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family. InterPro: Dak phosphatase domain; Function unclear; putative dihydroxyacetone kinase 2066694 5175596 CMM_1828 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dihydroxyacetone kinase YP_001222570.1 2066041 R 443906 CDS YP_001222571.1 148273010 5175580 complement(2066698..2067699) 1 NC_009480.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 2067699 5175580 CMM_1829 Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydroxyacetone kinase subunit DhaK YP_001222571.1 2066698 R 443906 CDS YP_001222572.1 148273011 5175565 2067981..2068733 1 NC_009480.1 putative glycerol uptake facilitator protein, MIP family (YP_061539.1| glycerol uptake facilitator protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056969.1| glycerol uptake facilitator protein [Propionibacterium acnes KPA171202]). cd00333, MIP, Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water,small neutral molecules, and ions out of and between cells. InterPro: MIP family.; High confidence in function and specificity; MIP family glycerol uptake facilitator protein 2068733 glpF 5175565 glpF Clavibacter michiganensis subsp. michiganensis NCPPB 382 MIP family glycerol uptake facilitator protein YP_001222572.1 2067981 D 443906 CDS YP_001222573.1 148273012 5175907 2068763..2070280 1 NC_009480.1 putative glycerol kinase (ATP:glycerol 3-phosphotransferase) (YP_061540.1| glycerol kinase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056968.1| glycerol kinase 2 [Propionibacterium acnes KPA171202]). pfam00370, FGGY_N, FGGY family of carbohydrate kinases, N-terminal domain. pfam02782, FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain.; High confidence in function and specificity; putative glycerol kinase 2070280 glpK 5175907 glpK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerol kinase YP_001222573.1 2068763 D 443906 CDS YP_001222574.1 148273013 5175821 complement(2070370..2071101) 1 NC_009480.1 conserved hypothetical protein (ZP_00106310.2| COG2135: Uncharacterized conserved protein [Nostoc punctiforme PCC 73102]; NP_824216.1| hypothetical protein SAV3040 [Streptomyces avermitilis MA-4680]). pfam02586,DUF159, Uncharacterised ACR, COG2135.; hypothetical protein 2071101 5175821 CMM_1832 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222574.1 2070370 R 443906 CDS YP_001222575.1 148273014 5175542 complement(2071163..2072218) 1 NC_009480.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 2072218 trpD 5175542 trpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 anthranilate phosphoribosyltransferase YP_001222575.1 2071163 R 443906 CDS YP_001222576.1 148273015 5173909 2072307..2072936 1 NC_009480.1 putative cytochrome c oxidase subunit III (YP_061962.1| cytochrome C oxidase subunit III [Leifsonia xyli subsp. xyli str. CTCB07]; AAS20084.1| cytochrome-c oxidase chain III [Arthrobacter aurescens]; T35533 cytochrome-c oxidase (EC 1.9.3.1) chain III - Streptomyces coelicolor). pfam00510, COX3, Cytochrome c oxidase subunit III.; Specificity unclear; putative cytochrome c oxidase subunit III 2072936 ctaE 5173909 ctaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome c oxidase subunit III YP_001222576.1 2072307 D 443906 CDS YP_001222577.1 148273016 5174852 2072963..2073763 1 NC_009480.1 putative ubiquinol-cytochrome c reductase cytochrome c subunit (YP_061961.1| ubiquinol-cytochrome C reductase cytochrome C subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789452.1| cytochrome C heme-binding subunit [Tropheryma whipplei TW08/27]). pfam00034,Cytochrom_C, Cytochrome c (twice).; Specificity unclear; putative ubiquinol-cytochrome c reductase cytochrome c subunit 2073763 qcrC 5174852 qcrC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ubiquinol-cytochrome c reductase cytochrome c subunit YP_001222577.1 2072963 D 443906 CDS YP_001222578.1 148273017 5173999 2073809..2074918 1 NC_009480.1 putative menaquinol-cytochrome C reductase iron-sulfur subunit (Rieske iron- sulfur protein)(YP_061960.1| Rieske iron-sulphur component of ubiQ-cytB reductase [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44345.1| ubiquinol-cytochrome c reductase iron-sulfur subunit [Tropheryma whipplei str. Twist]). pfam00355, Rieske,Rieske [2Fe-2S] domain. The rieske domain has a [2Fe-2S] centre.; High confidence in function and specificity; putative menaquinol-cytochrome C reductase iron-sulfur subunit 2074918 qcrA 5173999 qcrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative menaquinol-cytochrome C reductase iron-sulfur subunit YP_001222578.1 2073809 D 443906 CDS YP_001222579.1 148273018 5173394 2074902..2076533 1 NC_009480.1 putative menaquinol-cytochrome c reductase cytochrome B subunit (YP_061959.1| ubiquinol-cytochrome C reductase cytochrome B subunit [Leifsonia xyli subsp. xyli str. CTCB07]; AAO44346.1| ubiquinol- cytochrome c reductase cytochrome b subunit [Tropheryma whipplei str. Twist]).; High confidence in function and specificity; putative menaquinol-cytochrome c reductase cytochrome B subunit 2076533 qcrB 5173394 qcrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative menaquinol-cytochrome c reductase cytochrome B subunit YP_001222579.1 2074902 D 443906 CDS YP_001222580.1 148273019 5175154 2076648..2077565 1 NC_009480.1 putative rRNA methylase involved in antibiotic resistance (AAD12162.1| tylosin resistance protein [Streptomyces fradiae]; MYRA_MICGR MYCINAMICIN-RESISTANCE PROTEIN MYRA [Micromonospora griseorubida]). assignment unsure, also weak similarity to COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis. hemK_rel_arch: methylase putative pfam01209,Ubie_methyltran, ubiE/COQ5 methyltransferase family (weak similarity).; Function unclear; putative rRNA methylase involved in antibiotic resistance 2077565 5175154 CMM_1838 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative rRNA methylase involved in antibiotic resistance YP_001222580.1 2076648 D 443906 CDS YP_001222581.1 148273020 5173667 complement(2079396..2079833) 1 NC_009480.1 putative acetyltransferase (YP_002588.1| acetyltransferase [Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130]; YP_048936.1| putative GNAT-family acetyltransferase [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 2079833 5173667 CMM_1839 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222581.1 2079396 R 443906 CDS YP_001222582.1 148273021 5175526 complement(2079838..2080254) 1 NC_009480.1 conserved membrane protein (NP_301662.1| putative membrane protein [Mycobacterium leprae TN]; NP_626410.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). s1: malonate transporter MadL subunit; Conserved hypothetical protein; hypothetical protein 2080254 5175526 CMM_1840 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222582.1 2079838 R 443906 CDS YP_001222583.1 148273022 5175495 complement(2080256..2082001) 1 NC_009480.1 putative cytochrome c oxidase subunit I (NP_827224.1| putative cytochrome c oxidase subunit I [Streptomyces avermitilis MA-4680]; ZP_00293766.1| COG0843: Heme/copper-type cytochrome/quinol oxidases,subunit 1 [Thermobifida fusca]). pfam00115, COX1,Cytochrome C and Quinol oxidase polypeptide I. InterPro: Cytochrome c oxidase subunit I.; High confidence in function and specificity; putative cytochrome c oxidase subunit I 2082001 ctaD 5175495 ctaD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome c oxidase subunit I YP_001222583.1 2080256 R 443906 CDS YP_001222584.1 148273023 5175246 complement(2082014..2082925) 1 NC_009480.1 putative cytochrome c oxidase subunit II (Cytochrome AA3 subunit 2)(YP_062418.1| cytochrome C oxidase subunit II [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787371.1| cytochrome c oxidase subunit II [Tropheryma whipplei str. Twist]). pfam00116, COX2,Cytochrome C oxidase subunit II, periplasmic domain. InterPro: Cytochrome c oxidase subunit II.; High confidence in function and specificity; putative cytochrome c oxidase subunit II 2082925 ctaC 5175246 ctaC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytochrome c oxidase subunit II YP_001222584.1 2082014 R 443906 CDS YP_001222585.1 148273024 5174724 complement(2083050..2083412) 1 NC_009480.1 conserved hypothetical protein (YP_062419.1| Hypothetical protein Lxx15060 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00354123.1| COG0316: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]). pfam01521, HesB, HesB-like domain. InterPro: Hypothetical hesB/yadR/yfhF family TIGR00049: HesB/YadR/YfhF family protein; hypothetical protein 2083412 5174724 CMM_1843 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222585.1 2083050 R 443906 CDS YP_001222586.1 148273025 5175460 complement(2083540..2084961) 1 NC_009480.1 putative metallopeptidase (YP_062420.1| peptidase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961264.1| hypothetical protein MAP2330c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01546, Peptidase_M20,Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification. InterPro: Peptidase family M20/M25/M40; Family membership; hypothetical protein 2084961 5175460 CMM_1844 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222586.1 2083540 R 443906 CDS YP_001222587.1 148273026 5175486 2085002..2085595 1 NC_009480.1 putative membrane protein (YP_062421.1| Hypothetical protein Lxx15070 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00048249.2| hypothetical protein Magn021181 [Magnetospirillum magnetotacticum]; NP_626422.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 2085595 5175486 CMM_1845 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222587.1 2085002 D 443906 CDS YP_001222588.1 148273027 5175450 complement(2085626..2086660) 1 NC_009480.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2086660 pyrD 5175450 pyrD Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydroorotate dehydrogenase 2 YP_001222588.1 2085626 R 443906 CDS YP_001222589.1 148273028 5173040 complement(2086724..2087197) 1 NC_009480.1 putative transcriptional regulator (YP_062424.1| Hypothetical protein Lxx15110 [Leifsonia xyli subsp. xyli str. CTCB07]; CAE52895.1| regulatory protein [Streptomyces jumonjinensis]; NRDR_STRCL Putative regulatory protein nrdR). pfam03477, ATP-cone, ATP cone domain.; Function unclear; transcriptional regulator NrdR 2087197 nrdR 5173040 nrdR Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator NrdR YP_001222589.1 2086724 R 443906 CDS YP_001222590.1 148273029 5175424 complement(2087215..2088519) 1 NC_009480.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2088519 hisD 5175424 hisD Clavibacter michiganensis subsp. michiganensis NCPPB 382 histidinol dehydrogenase YP_001222590.1 2087215 R 443906 CDS YP_001222591.1 148273030 5173626 2088581..2089096 1 NC_009480.1 putative flavin-dependent reductase/monooxygenase (YP_062426.1| flavin-dependent reductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625377.1| putative flavin-dependent reductase [Streptomyces coelicolor A3(2)]; AAS77584.1| NADH-dependent FMN oxydoreductase [Rhodococcus sp. XP]). pfam01613, Flavin_Reduct, Flavin reductase like domain. This is a flavin reductase family consisting of enzymes known to be flavin reductases as well as various oxidoreductase and monooxygenase components. InterPro: Flavin reductase-like domain.; Function unclear; putative flavin-dependent reductase/monooxygenase 2089096 5173626 CMM_1849 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative flavin-dependent reductase/monooxygenase YP_001222591.1 2088581 D 443906 CDS YP_001222592.1 148273031 5175422 complement(2089128..2092640) 1 NC_009480.1 dnaE2; catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 2092640 dnaE 5175422 dnaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA polymerase III subunit alpha YP_001222592.1 2089128 R 443906 CDS YP_001222593.1 148273032 5173331 complement(2092717..2093634) 1 NC_009480.1 putative 23S rRNa-specific pseudouridine synthase (YP_062428.1| ribosomal large subunit pseudouridine synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827309.1| putative ribosomal large subunit pseudouridine synthase [Streptomyces avermitilis MA-4680]). pfam01479, S4, S4 domain. pfam00849,PseudoU_synth_2, RNA pseudouridylate synthase. Members of this family are involved in modifying bases in RNA molecules.; Specificity unclear; putative pseudouridine synthase 2093634 5173331 CMM_1851 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pseudouridine synthase YP_001222593.1 2092717 R 443906 CDS YP_001222594.1 148273033 5175437 complement(2093770..2094417) 1 NC_009480.1 putative cell division initiation protein (YP_062430.1| cell division initiation protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789188.1| putative cell division protein [Tropheryma whipplei TW08/27]; ZP_00226844.1| COG3599: Cell division initiation protein [Kineococcus radiotolerans SRS30216]). pfam05103, DivIVA,DivIVA protein.; Function unclear; putative cell division initiation protein 2094417 5175437 CMM_1852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell division initiation protein YP_001222594.1 2093770 R 443906 CDS YP_001222595.1 148273034 5175937 complement(2094564..2094869) 1 NC_009480.1 conserved membrane protein (YP_062431.1| Hypothetical protein Lxx15200 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291776.1| COG0762: Predicted integral membrane protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein 2094869 5175937 CMM_1853 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222595.1 2094564 R 443906 CDS YP_001222596.1 148273035 5175244 complement(2094930..2095424) 1 NC_009480.1 conserved hypothetical protein (AAT89327.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00209988.1| COG1799: Uncharacterized protein conserved in bacteria [Magnetospirillum magnetotacticum MS-1]). pfam04472, DUF552, Protein of unknown function (DUF552). Family of uncharacterized proteins. cynS: cyanate lyase; hypothetical protein 2095424 5175244 CMM_1854 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222596.1 2094930 R 443906 CDS YP_001222597.1 148273036 5174861 complement(2095473..2096204) 1 NC_009480.1 conserved hypothetical protein (ZP_00291774.1| COG0325: Predicted enzyme with a TIM-barrel fold [Thermobifida fusca]; NP_827302.1| hypothetical protein SAV6126 [Streptomyces avermitilis MA-4680]). InterPro: Uncharacterized pyridoxal-5-phosphate dependent enzyme family UPF0001.; hypothetical protein 2096204 5174861 CMM_1855 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222597.1 2095473 R 443906 CDS YP_001222598.1 148273037 5173827 complement(2096201..2097340) 1 NC_009480.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 2097340 ftsZ 5173827 ftsZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 cell division protein FtsZ YP_001222598.1 2096201 R 443906 CDS YP_001222599.1 148273038 5174253 complement(2097478..2098176) 1 NC_009480.1 putative cell division protein (NP_787358.1| cell division protein FtsQ [Tropheryma whipplei str. Twist]; ZP_00050269.2| COG1589: Cell division septal protein [Magnetospirillum magnetotacticum]). pfam03799, FtsQ, Cell division protein FtsQ.; Function unclear; cell division protein FtsQ 2098176 ftsQ 5174253 ftsQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 cell division protein FtsQ YP_001222599.1 2097478 R 443906 CDS YP_001222600.1 148273039 5174017 complement(2098710..2100140) 1 NC_009480.1 putative UDP-N-acetylmuramate-alanine ligase (UDP-N- acetylmuramoyl- L-alanine synthetase) (YP_062436.1| UDP-N-acetylmuramate-alanine ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789469.1| UDP-N-acetylmuramate--alanine ligase [Tropheryma whipplei TW08/27]). pfam01225,Mur_ligase, Mur ligase family, catalytic domain. This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. pfam02875, Mur_ligase_C, Mur ligase family, glutamate ligase domain. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; High confidence in function and specificity; putative UDP-N-acetylmuramate--alanine ligase 2100140 murC 5174017 murC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-N-acetylmuramate--alanine ligase YP_001222600.1 2098710 R 443906 CDS YP_001222601.1 148273040 5174124 complement(2100183..2101286) 1 NC_009480.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 2101286 murG 5174124 murG Clavibacter michiganensis subsp. michiganensis NCPPB 382 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_001222601.1 2100183 R 443906 CDS YP_001222602.1 148273041 5174503 complement(2101283..2102572) 1 NC_009480.1 putative cell division membrane protein (YP_062438.1| cell division protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827297.1| putative cell division protein FtsW [Streptomyces avermitilis MA-4680]). pfam01098, FTSW_RODA_SPOVE, Cell cycle protein. InterPro: Cell cycle proteins.; High confidence in function and specificity; putative cell division membrane protein 2102572 ftsW2 5174503 ftsW2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell division membrane protein YP_001222602.1 2101283 R 443906 CDS YP_001222603.1 148273042 5174091 complement(2102529..2104073) 1 NC_009480.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 2104073 murD 5174091 murD Clavibacter michiganensis subsp. michiganensis NCPPB 382 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_001222603.1 2102529 R 443906 CDS YP_001222604.1 148273043 5174961 complement(2104076..2105185) 1 NC_009480.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 2105185 mraY 5174961 mraY Clavibacter michiganensis subsp. michiganensis NCPPB 382 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_001222604.1 2104076 R 443906 CDS YP_001222605.1 148273044 5174579 complement(2105179..2106588) 1 NC_009480.1 putative UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme)(YP_062441.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-alanyl ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626347.1| putative UDP-N-acetylmuramoylalanyl- D-glutamyl-2,6-diaminopimelate-D-alanyl-alanyl ligase [Streptomyces coelicolor A3(2)]). Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity). pfam01225, Mur_ligase, Mur ligase family,catalytic domain. pfam02875, Mur_ligase_C, Mur ligase family, glutamate ligase domain.; High confidence in function and specificity; putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 2106588 murF 5174579 murF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_001222605.1 2105179 R 443906 CDS YP_001222606.1 148273045 5175062 complement(2106590..2108134) 1 NC_009480.1 putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase)(UDP-MurNAc-tripeptide synthetase) (YP_062442.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase [Leifsonia xyli subsp. xyli str. CTCB07]; Q82AE1|MURE_STRAW UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate ligase (UDP-N-acetylmuramyl-tripeptide synthetase)). Cell wall formation. Diaminopimelic acid adding enzyme (By similarity). pfam01225, Mur_ligase, Mur ligase family, catalytic domain. pfam02875, Mur_ligase_C, Mur ligase family,glutamate ligase domain. InterPro: Cytoplasmic peptidoglycan synthetases N-terminal.; Specificity unclear; putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase 2108134 murE 5175062 murE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase YP_001222606.1 2106590 R 443906 CDS YP_001222607.1 148273046 5174249 complement(2108147..2109928) 1 NC_009480.1 putative peptidoglycan glycosyltransferase/penicillin-binding protein (Peptidoglycan glycosyltransferase 3) (Penicillin-binding protein 3) (YP_062443.1| penicillin binding protein,transpeptidase domain [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789476.1| penicillin-binding protein [Tropheryma whipplei TW08/27]). Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates. pfam03717, PBP_dimer, Penicillin-binding Protein dimerisation domain. This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. pfam00905, Transpeptidase,Penicillin binding protein transpeptidase domain. InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity; putative peptidoglycan glycosyltransferase/penicillin-binding protein 2109928 ftsI 5174249 ftsI Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidoglycan glycosyltransferase/penicillin-binding protein YP_001222607.1 2108147 R 443906 CDS YP_001222608.1 148273047 5173986 complement(2110020..2110694) 1 NC_009480.1 conserved hypothetical protein (YP_062444.1| Hypothetical protein Lxx15330 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626350.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 2110694 5173986 CMM_1866 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222608.1 2110020 R 443906 CDS YP_001222609.1 148273048 5174097 complement(2110691..2111647) 1 NC_009480.1 putative S-adenosyl-methyltransferase (YP_062445.1| S-adenosyl- methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; Q9S2W4|MRAW_STRCO S-adenosyl-methyltransferase mraW). pfam01795, Methyltransf_5, MraW methylase family. Members of this family are probably SAM dependent methyltransferases. InterPro: Methyltransferase family; Function unclear; S-adenosyl-methyltransferase MraW 2111647 mraW 5174097 mraW Clavibacter michiganensis subsp. michiganensis NCPPB 382 S-adenosyl-methyltransferase MraW YP_001222609.1 2110691 R 443906 CDS YP_001222610.1 148273049 5175207 complement(2111751..2112182) 1 NC_009480.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 2112182 mraZ 5175207 mraZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 cell division protein MraZ YP_001222610.1 2111751 R 443906 CDS YP_001222611.1 148273050 5174748 complement(2112521..2112916) 1 NC_009480.1 conserved membrane protein (YP_062447.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789481.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00057748.1| hypothetical protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein 2112916 5174748 CMM_1869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222611.1 2112521 R 443906 CDS YP_001222612.1 148273051 5173954 2112994..2114115 1 NC_009480.1 putative geranylgeranyl pyrophosphate synthetase (GGPP synthetase) [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)] (YP_062448.1| geranylgeranyl pyrophosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225235.1| COG0142: Geranylgeranyl pyrophosphate synthase [Kineococcus radiotolerans SRS30216]). pfam00348, polyprenyl_synt,Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; Specificity unclear; putative geranylgeranyl pyrophosphate synthase 2114115 5173954 CMM_1870 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative geranylgeranyl pyrophosphate synthase YP_001222612.1 2112994 D 443906 CDS YP_001222613.1 148273052 5174827 complement(2114167..2114508) 1 NC_009480.1 conserved hypothetical protein, putative transcriptional regulator (YP_062449.1| Hypothetical protein Lxx15380 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733557.1| putative transcriptional regulatory protein [Streptomyces coelicolor A3(2)]; ZP_00056758.1| hypothetical protein [Thermobifida fusca]).; putative transcriptional regulator 2114508 5174827 CMM_1871 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001222613.1 2114167 R 443906 CDS YP_001222614.1 148273053 5174922 2114721..2115992 1 NC_009480.1 conserved hypothetical protein potentially involved in cell wall degradation (YP_062450.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630954.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_765874.1| autolysin (N-acetylmuramoyl-L-alanine amidase [Staphylococcus epidermidis ATCC 12228]). three LysM motifs are present: pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. InterPro: LysM motif pfam01476, LysM, LysM domain. The LysM (lysin motif) domain is about 40 residues long. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. The structure of this domain is known.; Function unclear; hypothetical protein 2115992 5174922 CMM_1872 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222614.1 2114721 D 443906 CDS YP_001222615.1 148273054 5174278 2116075..2118024 1 NC_009480.1 putative eukaryotic-type serine/threonine protein kinase (YP_062451.1| serine/threonine kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787344.1| serine/threonine-protein kinase [Tropheryma whipplei str. Twist]; NP_827268.1| putative eukaryotic-type serine/threonine protein kinase [Streptomyces avermitilis MA-4680]). pfam00069, Pkinase, Protein kinase domain. pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases (thrice). InterPro: Eukaryotic protein kinase smart00220, S_TKc,Serine/Threonine protein kinases, catalytic domain; Phosphotransferases. Serine or threonine-specific kinase subfamily. pfam00069, Pkinase, Protein kinase domain.; Specificity unclear; putative serine/threonine protein kinase 2118024 pknE 5174278 pknE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine protein kinase YP_001222615.1 2116075 D 443906 CDS YP_001222616.1 148273055 5173458 complement(2118093..2119463) 1 NC_009480.1 putative phospho-2-dehydro-3-deoxyheptonate aldolase (Phospho-2- keto-3-deoxyheptonate aldolase) (YP_062452.1| 2-dehydro- 3-deoxyphosphoheptonate aldolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827262.1| putative 2-dehydro-3-deoxyphosphoheptonate aldolase [Streptomyces avermitilis MA-4680]). pfam01474,DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyse the first step of the shikimate pathway.; High confidence in function and specificity; putative phospho-2-dehydro-3-deoxyheptonate aldolase 2119463 aroG 5173458 aroG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phospho-2-dehydro-3-deoxyheptonate aldolase YP_001222616.1 2118093 R 443906 CDS YP_001222617.1 148273056 5175473 complement(2119523..2120212) 1 NC_009480.1 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase (Lysophosphatidic acid acyltransferase) (YP_062453.1| 1-acylglycerol- 3-phosphate O-acyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827256.1| putative 1-acylglycerol-3-phosphate O-acyltransferase [Streptomyces avermitilis MA-4680]). ,pfam01553, Acyltransferase, Acyltransferase.; High confidence in function and specificity; putative acyltransferase 2120212 5175473 CMM_1875 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyltransferase YP_001222617.1 2119523 R 443906 CDS YP_001222618.1 148273057 5175730 complement(2120291..2121256) 1 NC_009480.1 putative glucokinase, putative catabolite repressor (EC 2.7.1.2) (Glucose kinase) (NP_823156.1| putative sugar kinase [Streptomyces avermitilis MA-4680]; P40184|GLK_STRCO Glucokinase (Glucose kinase); NP_787341.1| glucokinase [Tropheryma whipplei str. Twist]). , REQUIRED FOR GLUCOSE REPRESSION OF MANY DIFFERENT GENES. , pfam00480, ROK, ROK family.; High confidence in function and specificity; putative glucokinase, putative catabolite repressor 2121256 glkA 5175730 glkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucokinase, putative catabolite repressor YP_001222618.1 2120291 R 443906 CDS YP_001222619.1 148273058 5173658 2121390..2123216 1 NC_009480.1 putative long-chain-fatty-acid-CoA ligase (Long-chain acyl-CoA synthetase) (YP_062455.1| long-chain-fatty-acid-CoA ligase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827245.1| putative acyl-CoA synthetase, long-chain-fatty-acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme. InterPro: AMP-dependent synthetase and ligase; Specificity unclear; putative long-chain-fatty-acid-CoA ligase 2123216 5173658 CMM_1877 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative long-chain-fatty-acid-CoA ligase YP_001222619.1 2121390 D 443906 CDS YP_001222620.1 148273059 5174743 complement(2123253..2123744) 1 NC_009480.1 putative polypeptide deformylase 2 (Polypeptide deformylase 2)(YP_062456.1| polypeptide deformylase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293948.1| COG0242: N-formylmethionyl-tRNA deformylase [Thermobifida fusca]). Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. pfam01327,Pep_deformylase, Polypeptide deformylase. pept_deformyl: polypeptide deformylase; High confidence in function and specificity; putative polypeptide deformylase 2123744 defB 5174743 defB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polypeptide deformylase YP_001222620.1 2123253 R 443906 CDS YP_001222621.1 148273060 5175135 complement(2123779..2125251) 1 NC_009480.1 putative oxidoreductase (; AAO44726.1| pyridine nucleotide- disulphide oxidoreductase class I [Tropheryma whipplei str. Twist]). pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. 23387, pfam02852, Pyr_redox_dim,Pyridine nucleotide-disulphide oxidoreductase,dimerisation domain.; Function unclear; putative oxidoreductase ( E3 component of 2-oxoglutarate dehydrogenase complex) 2125251 5175135 CMM_1879 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase ( E3 component of 2-oxoglutarate dehydrogenase complex) YP_001222621.1 2123779 R 443906 CDS YP_001222622.1 148273061 5175423 complement(2125267..2128668) 1 NC_009480.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 2128668 pycA 5175423 pycA Clavibacter michiganensis subsp. michiganensis NCPPB 382 pyruvate carboxylase YP_001222622.1 2125267 R 443906 CDS YP_001222623.1 148273062 5175539 2128748..2129560 1 NC_009480.1 putative ATPase (YP_062459.1| plasmid partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787759.1| putative plasmid partitioning protein [Tropheryma whipplei str. Twist]). InterPro: ParA family ATPase; Family membership; putative ATPase 2129560 5175539 CMM_1881 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001222623.1 2128748 D 443906 CDS YP_001222624.1 148273063 5174525 complement(2129754..2130296) 1 NC_009480.1 putative transcriptional regulator, MerR family (YP_062460.1| Hypothetical protein Lxx15490 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055792.1| predicted transcriptional regulator [Propionibacterium acnes KPA171202]). pfam00376, MerR, MerR family regulatory protein. InterPro: Bacterial regulatory proteins MerR family.; Specificity unclear; MerR family transcriptional regulator 2130296 5174525 CMM_1882 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MerR family transcriptional regulator YP_001222624.1 2129754 R 443906 CDS YP_001222625.1 148273064 5175964 complement(2130838..2131539) 1 NC_009480.1 putative transcriptional regulator, MerR family (YP_062461.1| Hypothetical protein Lxx15500 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828158.1| hypothetical protein SAV6982 [Streptomyces avermitilis MA-4680]). pfam00376, MerR, MerR family regulatory protein. InterPro: Bacterial regulatory proteins MerR family.; Specificity unclear; MerR family transcriptional regulator 2131539 5175964 CMM_1883 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MerR family transcriptional regulator YP_001222625.1 2130838 R 443906 CDS YP_001222626.1 148273065 5175299 complement(2131539..2132021) 1 NC_009480.1 putative transcriptional regulator with FHA domain (YP_062462.1| Hypothetical protein Lxx15500 [Leifsonia xyli subsp. xyli str. CTCB07]; CAD67203.1| conserved hypothetical protein [Tropheryma whipplei TW08/27]; AAF07901.1| putative signal transduction protein GarA [Mycobacterium smegmatis]). InterPro: Forkhead-associated (FHA) domain; Function unclear; transcriptional regulator 2132021 5175299 CMM_1884 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator YP_001222626.1 2131539 R 443906 CDS YP_001222627.1 148273066 5175831 complement(2132110..2133495) 1 NC_009480.1 putative Na+/H+-dicarboxylate symporter, DAACS family (NP_823991.1| putative sodium:dicarboxylate symporter [Streptomyces avermitilis MA-4680]; NP_601793.1| Na+/H+-dicarboxylate symporter [Corynebacterium glutamicum ATCC 13032]). pfam00375, SDF,Sodium:dicarboxylate symporter family.; Specificity unclear; Na+/H+-dicarboxylate symporter 2133495 dctA 5175831 dctA Clavibacter michiganensis subsp. michiganensis NCPPB 382 Na+/H+-dicarboxylate symporter YP_001222627.1 2132110 R 443906 CDS YP_001222628.1 148273067 5174812 2133637..2135391 1 NC_009480.1 putative two-component system sensor kinase (NP_629573.1| putative two-component sensor kinase [Streptomyces coelicolor A3(2)]; Q9RC53|CITS_BACHD Sensor protein citS). pfam00989, PAS, PAS domain. pfam02518,HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal sensory_box: PAS domain S-box; Specificity unclear; putative two-component system sensor kinase 2135391 dctS 5174812 dctS Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001222628.1 2133637 D 443906 CDS YP_001222629.1 148273068 5173879 2135388..2136092 1 NC_009480.1 putative two-component system response regulator (NP_629572.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00198993.1| COG4565: Response regulator of citrate/malate metabolism [Kineococcus radiotolerans SRS30216]). cd00156, REC,Signal receiver domain. InterPro: Response regulator receiver domain; Specificity unclear; putative two-component system response regulator 2136092 dctR 5173879 dctR Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001222629.1 2135388 D 443906 CDS YP_001222630.1 148273069 5174093 2136186..2137232 1 NC_009480.1 putative zinc metalloprotease, family M4 (Q99132|PRT1_ERWCA Extracellular metalloprotease precursor; NP_626768.1| putative metalloprotease. [Streptomyces coelicolor A3(2)]). pfam02868,Peptidase_M4_C, Thermolysin metallopeptidase, alpha-helical domain. pfam01447, Peptidase_M4, Thermolysin metallopeptidase, catalytic domain. InterPro: Thermolysin metalloprotease (M4) family; Specificity unclear; zinc metalloprotease family M4 2137232 5174093 CMM_1888 Clavibacter michiganensis subsp. michiganensis NCPPB 382 zinc metalloprotease family M4 YP_001222630.1 2136186 D 443906 CDS YP_001222631.1 148273070 5175112 2137233..2137514 1 NC_009480.1 hypothetical protein (ZP_00413008.1| hypothetical protein ArthDRAFT_1891 [Arthrobacter sp. FB24]).; hypothetical protein 2137514 5175112 CMM_1889 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222631.1 2137233 D 443906 CDS YP_001222632.1 148273071 5175860 2137511..2138371 1 NC_009480.1 conserved hypothetical protein (YP_061831.1| Hypothetical protein Lxx08190 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_216549.1| hypothetical protein Rv2033c [Mycobacterium tuberculosis H37Rv]; ZP_00227509.1| hypothetical protein Krad06003896 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2138371 5175860 CMM_1890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222632.1 2137511 D 443906 CDS YP_001222633.1 148273072 5175805 complement(2138396..2139469) 1 NC_009480.1 putative transcriptional regulator, LacI family (CAB07149.1| TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LACI-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_940300.1| Putative LacI-family transcriptional regulator [Corynebacterium diphtheriae NCTC 13129]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family. smart00354,HTH_LACI, helix_turn _helix lactose operon repressor; Specificity unclear; hypothetical protein 2139469 5175805 CMM_1891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222633.1 2138396 R 443906 CDS YP_001222634.1 148273073 5175599 2139624..2140790 1 NC_009480.1 putative polyamine ABC transporter, substrate binding protein (NP_627660.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00130059.1| COG4134: ABC-type uncharacterized transport system, periplasmic component [Desulfovibrio desulfuricans G20]). pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative polyamine ABC transporter, substrate binding protein 2140790 5175599 CMM_1892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyamine ABC transporter, substrate binding protein YP_001222634.1 2139624 D 443906 CDS YP_001222635.1 148273074 5175050 2140787..2141740 1 NC_009480.1 putative polyamine ABC transporter, permease component (NP_827155.1| putative maltose permease [Streptomyces avermitilis MA-4680]; |NP_831069.1| Spermidine/putrescine transport system permease protein potB [Bacillus cereus ATCC 14579]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polyamine ABC transporter, permease component 2141740 5175050 CMM_1893 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyamine ABC transporter, permease component YP_001222635.1 2140787 D 443906 CDS YP_001222636.1 148273075 5175238 2141740..2142555 1 NC_009480.1 putative polyamine ABC transporter, permease component (CAG77144.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]; ZP_00126942.1| COG1177: ABC-type spermidine/putrescine transport system, permease component II [Pseudomonas syringae pv. syringae B728a]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polyamine ABC transporter, permease component 2142555 5175238 CMM_1894 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyamine ABC transporter, permease component YP_001222636.1 2141740 D 443906 CDS YP_001222637.1 148273076 5175930 2142563..2143714 1 NC_009480.1 putative polyamine ABC transporter, ATPase component (NP_579699.1| putative multiple sugar-binding transport ATP-binding protein [Pyrococcus furiosus DSM 3638]; ZP_00089377.1| COG3842: ABC-type spermidine/putrescine transport systems, ATPase components [Azotobacter vinelandii]). InterPro: AAA ATPase superfamily pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative polyamine ABC transporter, ATPase component 2143714 5175930 CMM_1895 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyamine ABC transporter, ATPase component YP_001222637.1 2142563 D 443906 CDS YP_001222638.1 148273077 5175841 2143711..2145303 1 NC_009480.1 two-domain protein (Glycerophosphoryl diester phosphodiesterase, Inositol monophosphatase). N-terminal: COG0584, UgpQ, Glycerophosphoryl diester phosphodiesterase, pfam03009, GDPD, Glycerophosphoryl diester phosphodiesterase family (NP_823772.1| putative glycerophosphoryl diester phosphodiesterase [Streptomyces avermitilis MA-4680]; NP_622644.1| Glycerophosphoryl diester phosphodiesterase [Thermoanaerobacter tengcongensis]). C-terminal: COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; pfam00459, Inositol_P,Inositol monophosphatase family (NP_699895.1| inositol monophosphatase family protein [Brucella suis 1330]; P44333|SUHB_HAEIN Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase)). Inositol-1-monophosphatase (EC 3.1.3.25) (IMPase) (Inositol-1-phosphatase) (I-1-Pase). InterPro: Inositol monophosphatase; High confidence in function and specificity; bifunctional glycerophosphoryl diester phosphodiesterase/inositol monophosphatase 2145303 5175841 CMM_1896 Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional glycerophosphoryl diester phosphodiesterase/inositol monophosphatase YP_001222638.1 2143711 D 443906 CDS YP_001222639.1 148273078 5175322 complement(2145300..2146256) 1 NC_009480.1 NTP pyrophosphohydrolase 2146256 5175322 CMM_1897 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NTP pyrophosphohydrolase YP_001222639.1 2145300 R 443906 CDS YP_001222640.1 148273079 5174072 2146297..2146776 1 NC_009480.1 hypothetical protein 2146776 5174072 CMM_1898 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222640.1 2146297 D 443906 CDS YP_001222641.1 148273080 5175830 complement(2146817..2147833) 1 NC_009480.1 putative Zinc-dependant dehydrogenase (NP_962452.1| hypothetical protein MAP3518c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_733654.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative Zinc-dependant dehydrogenase 2147833 5175830 CMM_1899 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zinc-dependant dehydrogenase YP_001222641.1 2146817 R 443906 CDS YP_001222642.1 148273081 5174365 2147962..2148690 1 NC_009480.1 conserved membrane protein (NP_832507.1| Integral membrane protein [Bacillus cereus ATCC 14579]; ZP_00227256.1| COG2324: Predicted membrane protein [Kineococcus radiotolerans SRS30216]).; Conserved hypothetical protein; hypothetical protein 2148690 5174365 CMM_1900 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222642.1 2147962 D 443906 CDS YP_001222643.1 148273082 5174327 2148722..2149471 1 NC_009480.1 hypothetical protein 2149471 5174327 CMM_1901 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222643.1 2148722 D 443906 CDS YP_001222644.1 148273083 5175867 complement(2149468..2150961) 1 NC_009480.1 putative amine oxidase (NP_746273.1| conserved hypothetical protein [Pseudomonas putida KT2440]; ZP_00225945.1| COG1231: Monoamine oxidase [Kineococcus radiotolerans SRS30216]). , pfam01593, Amino_oxidase,Flavin containing amine oxidoreductase.; Function unclear; hypothetical protein 2150961 5175867 CMM_1902 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222644.1 2149468 R 443906 CDS YP_001222645.1 148273084 5174844 2151005..2151433 1 NC_009480.1 putative RNA-binding heat shock protein (NP_626252.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_601324.1| ribosome- associated heat shock protein [Corynebacterium glutamicum ATCC 13032]). smart00363, S4, S4 RNA-binding domain; Function unclear; putative heat shock protein 2151433 5174844 CMM_1903 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative heat shock protein YP_001222645.1 2151005 D 443906 CDS YP_001222646.1 148273085 5174793 complement(2151430..2152398) 1 NC_009480.1 conserved hypothetical protein (ZP_00227630.1| hypothetical protein Krad06003512 [Kineococcus radiotolerans SRS30216]; NP_939566.1| Conserved hypothetical protein [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 2152398 5174793 CMM_1904 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222646.1 2151430 R 443906 CDS YP_001222647.1 148273086 5174373 2152491..2152925 1 NC_009480.1 hypothetical protein 2152925 5174373 CMM_1905 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222647.1 2152491 D 443906 CDS YP_001222648.1 148273087 5175946 2153147..2154175 1 NC_009480.1 hypothetical protein 2154175 5175946 CMM_1906 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222648.1 2153147 D 443906 CDS YP_001222649.1 148273088 5174296 2154219..2154473 1 NC_009480.1 hypothetical protein 2154473 5174296 CMM_1907 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222649.1 2154219 D 443906 CDS YP_001222650.1 148273089 5174404 complement(2154561..2155541) 1 NC_009480.1 putative chaperone (ZP_00041700.1| COG2214: DnaJ-class molecular chaperone [Xylella fastidiosa Ann-1]; NP_111006.1| Molecular chaperone (DnaJ-related) [Thermoplasma volcanium GSS1]). InterPro: DnaJ N-terminal domain pfam00226, DnaJ, DnaJ domain.; Family membership; putative chaperone 2155541 5174404 CMM_1908 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chaperone YP_001222650.1 2154561 R 443906 CDS YP_001222651.1 148273090 5174903 complement(2155538..2157205) 1 NC_009480.1 putative UDP-glucose-4-epimerase (NP_302449.1| probable UDP-glucose-4-epimerase [Mycobacterium leprae TN]; NP_630132.1| conserved hypothetical protein SC1C3.09 [Streptomyces coelicolor A3(2)]).; Function unclear; putative UDP-glucose-4-epimerase 2157205 cpsY 5174903 cpsY Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-glucose-4-epimerase YP_001222651.1 2155538 R 443906 CDS YP_001222652.1 148273091 5174234 complement(2157386..2158114) 1 NC_009480.1 hypothetical protein 2158114 5174234 CMM_1910 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222652.1 2157386 R 443906 CDS YP_001222653.1 148273092 5174126 2158290..2159201 1 NC_009480.1 putative dehydrogenase (NP_772800.1| blr6160 [Bradyrhizobium japonicum]; ZP_00228758.1| COG1319: Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Kineococcus radiotolerans SRS30216]). pfam00941, FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase.; Function unclear; hypothetical protein 2159201 5174126 CMM_1911 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222653.1 2158290 D 443906 CDS YP_001222654.1 148273093 5174139 2159198..2162083 1 NC_009480.1 putative dehydrogenase (ZP_00228757.1| COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Kineococcus radiotolerans SRS30216]; NP_772801.1| blr6161 [Bradyrhizobium japonicum]). N-terminal: COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; pfam01799, Fer2_2, [2Fe-2S] binding domain. C-terminal: COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase,large subunit CoxL/CutL homologs; pfam01315, Ald_Xan_dh_C,Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain.; pfam02738, Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain (; Function unclear; hypothetical protein 2162083 5174139 CMM_1912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222654.1 2159198 D 443906 CDS YP_001222655.1 148273094 5175031 complement(2162103..2163395) 1 NC_009480.1 putative amino acid permease, APC family (NP_336518.1| amino acid permease [Mycobacterium tuberculosis CDC1551]; NP_628774.1| putative amino acid transporter [Streptomyces coelicolor A3(2)]). InterPro: Amino acid permease pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease APC family 2163395 5175031 CMM_1913 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid permease APC family YP_001222655.1 2162103 R 443906 CDS YP_001222656.1 148273095 5175817 complement(2163392..2164498) 1 NC_009480.1 conserved hypothetical protein (NP_823241.1| hypothetical protein SAV2065 [Streptomyces avermitilis MA-4680]; CAD47932.1| putative carbon monoxide dehydrogenase subunit F [Arthrobacter nicotinovorans]).; Function unclear; hypothetical protein 2164498 5175817 CMM_1914 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222656.1 2163392 R 443906 CDS YP_001222657.1 148273096 5175782 2164684..2165313 1 NC_009480.1 hypothetical protein 2165313 5175782 CMM_1915 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222657.1 2164684 D 443906 CDS YP_001222658.1 148273097 5174491 2165363..2166028 1 NC_009480.1 hypothetical protein 2166028 5174491 CMM_1916 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222658.1 2165363 D 443906 CDS YP_001222659.1 148273098 5175881 2166240..2167694 1 NC_009480.1 putative guanine deaminase (Guanine aminohydrolase) (NP_746397.1| guanine aminohydrolase [Pseudomonas putida KT2440]; P76641|GUAD_ECOLI Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH)). pfam01979, Amidohydro_1, Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily.; Specificity unclear; putative guanine deaminase 2167694 5175881 CMM_1917 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative guanine deaminase YP_001222659.1 2166240 D 443906 CDS YP_001222660.1 148273099 5174290 complement(2167709..2168488) 1 NC_009480.1 putative membrane-associated acid phosphatase (ZP_00107252.1| COG0671: Membrane-associated phospholipid phosphatase [Nostoc punctiforme]; ZP_00052741.2| COG0671: Membrane-associated phospholipid phosphatase [Magnetospirillum magnetotacticum]). InterPro: PA-phosphatase related phosphoesterase smart00014, acidPPc,Acid phosphatase homologues pfam01569, PAP2, PAP2 superfamily.; Family membership; putative membrane-associated acid phosphatase 2168488 5174290 CMM_1918 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-associated acid phosphatase YP_001222660.1 2167709 R 443906 CDS YP_001222661.1 148273100 5174170 complement(2168485..2168853) 1 NC_009480.1 hypothetical protein 2168853 5174170 CMM_1919 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222661.1 2168485 R 443906 CDS YP_001222662.1 148273101 5174426 2168921..2169544 1 NC_009480.1 conserved hypothetical protein (ZP_00228764.1| COG2068: Uncharacterized MobA-related protein [Kineococcus radiotolerans SRS30216]; NP_630344.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 2169544 5174426 CMM_1920 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222662.1 2168921 D 443906 CDS YP_001222663.1 148273102 5175969 complement(2169552..2170271) 1 NC_009480.1 hypothetical protein 2170271 5175969 CMM_1921 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222663.1 2169552 R 443906 CDS YP_001222664.1 148273103 5174476 complement(2170402..2170863) 1 NC_009480.1 conserved hypothetical protein (ZP_00294077.1| COG0822: NifU homolog involved in Fe-S cluster formation [Thermobifida fusca]; NP_816042.1| NifU family protein [Enterococcus faecalis V583]). pfam01592, NifU_N, NifU-like N terminal domain. This domain is found in NifU in combination with pfam01106. This domain is found on isolated proteins in several bacterial species.; Function unclear; hypothetical protein 2170863 5174476 CMM_1922 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222664.1 2170402 R 443906 CDS YP_001222665.1 148273104 5175527 complement(2170932..2172743) 1 NC_009480.1 putative gamma-glutamyltranspeptidase (ZP_00227294.1| COG0405: Gamma-glutamyltransferase [Kineococcus radiotolerans SRS30216]; NP_630062.1| putative transferase [Streptomyces coelicolor A3(2)]). g_glut_trans: gamma-glutamyltranspepti; High confidence in function and specificity; hypothetical protein 2172743 ggtA 5175527 ggtA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222665.1 2170932 R 443906 CDS YP_001222666.1 148273105 5175685 2172845..2174284 1 NC_009480.1 putative efflux MFS permease (NP_824729.1| putative integral membrane transport protein [Streptomyces avermitilis MA-4680]; ZP_00186259.2| COG0477: Permeases of the major facilitator superfamily [Rubrobacter xylanophilus DSM 9941]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters; Specificity unclear; putative efflux MFS permease 2174284 5175685 CMM_1924 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative efflux MFS permease YP_001222666.1 2172845 D 443906 CDS YP_001222667.1 148273106 5174333 2174382..2175410 1 NC_009480.1 putative monooxygenase (NP_772138.1| blr5498 [Bradyrhizobium japonicum USDA 110]; ZP_00007886.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Rhodobacter sphaeroides]). pfam00296, Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase/oxidoreductase 2175410 5174333 CMM_1925 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase/oxidoreductase YP_001222667.1 2174382 D 443906 CDS YP_001222668.1 148273107 5174855 2175523..2176338 1 NC_009480.1 putative esterase (ZP_00220463.1| COG2755: Lysophospholipase L1 and related esterases [Burkholderia cepacia R1808]; NP_104793.1| hypothetical protein mlr3756 [Mesorhizobium loti MAFF303099]).; Function unclear; putative esterase 2176338 5174855 CMM_1926 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001222668.1 2175523 D 443906 CDS YP_001222669.1 148273108 5175220 2176335..2177027 1 NC_009480.1 putative sugar kinase (ZP_00292020.1| COG0063: Predicted sugar kinase [Thermobifida fusca]; NP_771587.1| bll4947 [Bradyrhizobium japonicum]). pfam03853, YjeF_N,YjeF-related protein N-terminus.; Function unclear; hypothetical protein 2177027 5175220 CMM_1927 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222669.1 2176335 D 443906 CDS YP_001222670.1 148273109 5173627 2177183..2177479 1 NC_009480.1 Hypothetical protein; hypothetical protein 2177479 5173627 CMM_1928 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222670.1 2177183 D 443906 CDS YP_001222671.1 148273110 5174926 complement(2177572..2178600) 1 NC_009480.1 putative Zinc-dependant quinone oxidoreductase (NADPH:quinone reductase) (ZP_00190206.2| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_898787.1| putative quinone oxidoreductase [Rhodococcus erythropolis]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily.; High confidence in function and specificity; putative quinone oxidoreductase 2178600 5174926 CMM_1929 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative quinone oxidoreductase YP_001222671.1 2177572 R 443906 CDS YP_001222672.1 148273111 5175676 complement(2178642..2180207) 1 NC_009480.1 conserved hypothetical protein (ZP_00121600.2| COG1574: Predicted metal-dependent hydrolase with the TIM-barrel fold [Bifidobacterium longum DJO10A]; ZP_00225851.1| COG1574: Predicted metal-dependent hydrolase with the TIM-barrel fold [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 2180207 5175676 CMM_1930 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222672.1 2178642 R 443906 CDS YP_001222673.1 148273112 5173084 complement(2180204..2180872) 1 NC_009480.1 putative transcriptional regulator (NP_845841.1| protease synthase and sporulation negative regulatory protein PAI 2 [Bacillus anthracis str. Ames]; ZP_00118684.1| COG2808: Transcriptional regulator [Cytophaga hutchinsonii]). pfam04299, Neg_reg, Negative transcriptional regulator. In Bacillus subtilis, family member PAI 2 is involved in the negative regulation of protease synthesis and sporulation.; Specificity unclear; hypothetical protein 2180872 5173084 CMM_1931 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222673.1 2180204 R 443906 CDS YP_001222674.1 148273113 5174645 complement(2180987..2182702) 1 NC_009480.1 putative acyl-coenzyme A synthetase (ZP_00058202.1| COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Thermobifida fusca]; NP_630298.1| putative acetyl-coenzyme A synthetase [Streptomyces coelicolor A3(2)]). InterPro: AMP-dependent synthetase and ligase pfam00501, AMP-binding, AMP-binding enzyme.; Specificity unclear; putative acyl-CoA synthetase 2182702 5174645 CMM_1932 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA synthetase YP_001222674.1 2180987 R 443906 CDS YP_001222675.1 148273114 5174323 2182827..2183663 1 NC_009480.1 putative arylesterase (ZP_00228881.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Kineococcus radiotolerans SRS30216]; NP_832864.1| Arylesterase [Bacillus cereus ATCC 14579]). InterPro: Alpha/beta hydrolase fold pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Function unclear; putative arylesterase 2183663 5174323 CMM_1933 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative arylesterase YP_001222675.1 2182827 D 443906 CDS YP_001222676.1 148273115 5173853 complement(2183722..2184069) 1 NC_009480.1 putative transcriptional regulator, LysR-family (AAN70636.1| transcriptional regulator, LysR family [Pseudomonas putida KT2440]; ZP_00091330.1| COG0583: Transcriptional regulator [Azotobacter vinelandii]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family.; Hypothetical protein; LysR family transcriptional regulator 2184069 5173853 CMM_1934 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001222676.1 2183722 R 443906 CDS YP_001222677.1 148273116 5174940 2184187..2184807 1 NC_009480.1 putative pyrophosphohydrolase (NP_939379.1| Putative NUDIX-family hydrolase [Corynebacterium diphtheriae NCTC 13129]; NP_765595.1| mutator protein mutT [Staphylococcus epidermidis ATCC 12228]). pfam00293,NUDIX, NUDIX domain. also high similarity to: COG1051, ADP-ribose pyrophosphatase; Family membership; putative mutT-like hydrolase 2184807 5174940 CMM_1935 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mutT-like hydrolase YP_001222677.1 2184187 D 443906 CDS YP_001222678.1 148273117 5173726 2184987..2185898 1 NC_009480.1 putative lipase (gb|AAA53485.1| lipase precursor [Streptomyces albus]; ZP_00228194.1| COG4188: Predicted dienelactone hydrolase [Kineococcus radiotolerans SRS30216]). InterPro: Esterase/lipase/thioesterase family active site pfam01738, DLH, Dienelactone hydrolase family.; Family membership; putative lipase 2185898 5173726 CMM_1936 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lipase YP_001222678.1 2184987 D 443906 CDS YP_001222679.1 148273118 5175875 2186146..2187582 1 NC_009480.1 putative membrane protein (CAA18059.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; ZP_00059568.1| COG2966: Uncharacterized conserved protein [Thermobifida fusca]). pfam06738, DUF1212, Protein of unknown function (DUF1212). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. Some family members are membrane proteins.; Family membership; hypothetical protein 2187582 5175875 CMM_1937 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222679.1 2186146 D 443906 CDS YP_001222680.1 148273119 5175216 2187675..2188910 1 NC_009480.1 putative peptidase, family M20D (NP_739352.1| putative peptidase [Corynebacterium efficiens YS-314]; NP_628283.1| peptidase [Streptomyces coelicolor A3(2)]). ,pfam01546, Peptidase_M20, Peptidase family M20/M25/M40. This family includes a range of zinc metallopeptidases belonging to several families in the peptidase classification.; Specificity unclear; peptidase family M20D 2188910 5175216 CMM_1938 Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptidase family M20D YP_001222680.1 2187675 D 443906 CDS YP_001222681.1 148273120 5174547 complement(2188914..2189210) 1 NC_009480.1 putative transposase (NP_961542.1| hypothetical protein MAP2608 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_822059.1| putative transposase [Streptomyces avermitilis MA-4680])., ,pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome.; Family membership; IS481 family transposase 2189210 5174547 CMM_1939 Clavibacter michiganensis subsp. michiganensis NCPPB 382 IS481 family transposase YP_001222681.1 2188914 R 443906 CDS YP_001222682.1 148273121 5174939 complement(2189210..2189917) 1 NC_009480.1 putative transposase (NP_961542.1| hypothetical protein MAP2608 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_628857.1| putative insertion element IS1652 transposase [Streptomyces coelicolor A3(2)]).; Family membership; IS481 family transposase 2189917 5174939 CMM_1940 Clavibacter michiganensis subsp. michiganensis NCPPB 382 IS481 family transposase YP_001222682.1 2189210 R 443906 CDS YP_001222683.1 148273122 5175298 complement(2191227..2191718) 1 NC_009480.1 conserved membrane protein (NP_737704.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]; ZP_00209412.1| hypothetical protein Magn023696 [Magnetospirillum magnetotacticum]).; hypothetical protein 2191718 5175298 CMM_1941 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222683.1 2191227 R 443906 CDS YP_001222684.1 148273123 5174418 2191851..2192852 1 NC_009480.1 conserved hypothetical protein, putative extracellular serine protease (NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]; NP_642686.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]).; Function unclear; putative extracellular serine protease 2192852 ppaG 5174418 ppaG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001222684.1 2191851 D 443906 CDS YP_001222685.1 148273124 5174430 complement(2192928..2194061) 1 NC_009480.1 hypothetical protein 2194061 5174430 CMM_1943 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222685.1 2192928 R 443906 CDS YP_001222686.1 148273125 5174331 complement(2194058..2195218) 1 NC_009480.1 hypothetical protein 2195218 5174331 CMM_1944 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222686.1 2194058 R 443906 CDS YP_001222687.1 148273126 5174287 complement(2195319..2196569) 1 NC_009480.1 putative acyl-CoA dehydrogenase (ZP_00140036.1| COG1960: Acyl-CoA dehydrogenases [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00226266.1| COG1960: Acyl-CoA dehydrogenases [Kineococcus radiotolerans SRS30216]).; Function unclear; putative acyl-CoA dehydrogenase 2196569 5174287 CMM_1945 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA dehydrogenase YP_001222687.1 2195319 R 443906 CDS YP_001222688.1 148273127 5174356 complement(2196566..2197936) 1 NC_009480.1 putative oxidoreductase/monooxygenase (ZP_00228688.1| COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_794917.1| monooxygenase, DszA family [Pseudomonas syringae pv. tomato str. DC3000]).; Specificity unclear; putative oxidoreductase/monooxygenase 2197936 5174356 CMM_1946 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase/monooxygenase YP_001222688.1 2196566 R 443906 CDS YP_001222689.1 148273128 5175461 2198204..2199196 1 NC_009480.1 putative extracellular serine protease (NP_779168.1| conserved hypothetical protein [Xylella fastidiosa Temecula1]; ZP_00293497.1| COG3591: V8-like Glu-specific endopeptidase [Thermobifida fusca]).; Function unclear; putative extracellular serine protease 2199196 ppaH 5175461 ppaH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001222689.1 2198204 D 443906 CDS YP_001222690.1 148273129 5174360 2199308..2200276 1 NC_009480.1 putative extracellular serine protease (NP_297821.1| hypothetical protein XF0531 [Xylella fastidiosa 9a5c]; NP_298723.1| hypothetical protein XF1434 [Xylella fastidiosa 9a5c]).; Conserved hypothetical protein; putative extracellular serine protease 2200276 ppaI 5174360 ppaI Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative extracellular serine protease YP_001222690.1 2199308 D 443906 CDS YP_001222691.1 148273130 5174587 2200532..2202031 1 NC_009480.1 putative shikimate MFS permease (ZP_00186986.1| COG0477: Permeases of the major facilitator superfamily [Rubrobacter xylanophilus DSM 9941]; NP_625306.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]; NP_756685.1| Shikimate transporter [Escherichia coli CFT073]). InterPro: General substrate transporters pfam00083, Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative MFS permease 2202031 5174587 CMM_1949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001222691.1 2200532 D 443906 CDS YP_001222692.1 148273131 5174371 complement(2202084..2203658) 1 NC_009480.1 putative choline dehydrogenase (AAS99880.1| choline oxidase [Arthrobacter globiformis]; NP_828122.1| putative GMC-family oxidoreductase [Streptomyces avermitilis MA-4680]). InterPro: Glucose-methanol-choline (GMC) oxidoreductase pfam00732, GMC_oxred_N, GMC oxidoreductase. This family of proteins bind FAD as a cofactor. pfam05199,GMC_oxred_C, GMC oxidoreductase. This domain found associated with pfam00732.; Specificity unclear; putative oxidoreductase 2203658 5174371 CMM_1950 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222692.1 2202084 R 443906 CDS YP_001222693.1 148273132 5175850 complement(2203679..2205178) 1 NC_009480.1 putative betaine aldehyde dehydrogenase (EC 1.2.1.8) (NP_828124.1| putative betaine aldehyde dehydrogenase [Streptomyces avermitilis MA-4680]; NP_940508.1| betaine aldehyde dehydrogenase [Corynebacterium diphtheriae]). THIS IS A SOLUBLE NAD-DEPENDENT BETAINE ALDEHYDE-SPECIFIC DEHYDROGENASE. ESSENTIAL FOR THE UTILIZATION OF CHOLINE AS A PRECURSOR. InterPro: Aldehyde dehydrogenase family pfam00171, Aldedh,Aldehyde dehydrogenase family. This family of dehydrogenases act on aldehyde substrates. Members use NADP as a cofactor.; Specificity unclear; putative glycine betaine aldehyde dehydrogenase 2205178 5175850 CMM_1951 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycine betaine aldehyde dehydrogenase YP_001222693.1 2203679 R 443906 CDS YP_001222694.1 148273133 5175934 complement(2205175..2207286) 1 NC_009480.1 high-affinity choline/glycine/betaine transport protein, BCCT family (CAG74648.1| high-affinity choline transport protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_308387.1| high-affinity choline transport [Escherichia coli O157:H7]). High-affinity uptake of choline driven by a proton- motive force. InterPro: BCCT transporter pfam02028, BCCT, BCCT family transporter bcct: choline/carnitine/betaine transp; High confidence in function and specificity; BCCT family high-affinity choline/glycine/betaine transport protein 2207286 betT 5175934 betT Clavibacter michiganensis subsp. michiganensis NCPPB 382 BCCT family high-affinity choline/glycine/betaine transport protein YP_001222694.1 2205175 R 443906 CDS YP_001222695.1 148273134 5173344 complement(2207514..2208182) 1 NC_009480.1 conserved hypothetical protein (ZP_00199506.1| hypothetical protein Krad06000279 [Kineococcus radiotolerans SRS30216]; NP_736786.1| hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 2208182 5173344 CMM_1953 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222695.1 2207514 R 443906 CDS YP_001222696.1 148273135 5175872 complement(2208179..2208811) 1 NC_009480.1 conserved hypothetical protein (ZP_00199507.1| COG4950: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_792620.1| alkylhydroperoxidase AhpD domain protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_773540.1| bll6900 [Bradyrhizobium japonicum]). InterPro: Alkylhydroperoxidase AhpD family core domain ahpD_dom: alkylhydroperoxidase AhpD famil; hypothetical protein 2208811 5175872 CMM_1954 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222696.1 2208179 R 443906 CDS YP_001222697.1 148273136 5174071 complement(2208808..2209464) 1 NC_009480.1 conserved hypothetical protein (ZP_00199507.1| COG4950: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_773541.1| bll6901 [Bradyrhizobium japonicum]). ahpD_dom: alkylhydroperoxidase AhpD fami; Function unclear; hypothetical protein 2209464 5174071 CMM_1955 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222697.1 2208808 R 443906 CDS YP_001222698.1 148273137 5174684 complement(2209461..2210534) 1 NC_009480.1 putative monooxygenase (YP_048200.1| putative monooxygenase [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_822331.1| putative monooxygenase [Streptomyces avermitilis MA-4680]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase. InterPro: Bacterial luciferase weak similaritiy to pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase 2210534 5174684 CMM_1956 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001222698.1 2209461 R 443906 CDS YP_001222699.1 148273138 5174212 complement(2210531..2212168) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (two fused ATPase domains; NP_601634.1| ABC-type transporter, duplicated ATPase component [Corynebacterium glutamicum ATCC 13032]; NP_789094.1| putative ABC transporter ATP-binding subunit [Tropheryma whipplei TW08/27]). InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 2212168 5174212 CMM_1957 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001222699.1 2210531 R 443906 CDS YP_001222700.1 148273139 5175795 complement(2212165..2213013) 1 NC_009480.1 putative peptide ABC transport system, permease component (YP_048202.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]; CAF21099.1| ABC-type dipeptide/oligopeptide/nickel transport systems, permease component [Corynebacterium glutamicum ATCC 13032]; NP_960023.1| hypothetical protein MAP1089 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative peptide ABC transport system, permease component 2213013 5175795 CMM_1958 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transport system, permease component YP_001222700.1 2212165 R 443906 CDS YP_001222701.1 148273140 5175149 complement(2213010..2213945) 1 NC_009480.1 putative peptide ABC transporter, permease component (NP_738943.1| putative transport protein [Corynebacterium efficiens YS-314]; YP_048203.1| ABC transporter permease protein [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 2213945 5175149 CMM_1959 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001222701.1 2213010 R 443906 CDS YP_001222702.1 148273141 5175537 complement(2213986..2215638) 1 NC_009480.1 putative peptide ABC transporter, substrate-binding protein (CAF21101.1| ABC-type dipeptide/oligopeptide/nickel transport systems, secreted component [Corynebacterium glutamicum ATCC 13032]; YP_048204.1| ABC-type transporter, substrate binding protein [Erwinia carotovora subsp. atroseptica SCRI1043]; NP_960020.1| hypothetical protein MAP1086 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 2215638 5175537 CMM_1960 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001222702.1 2213986 R 443906 CDS YP_001222703.1 148273142 5175197 2215852..2216343 1 NC_009480.1 putative acetyltransferase (ZP_00191833.2| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Kineococcus radiotolerans SRS30216]; ZP_00182088.2| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Exiguobacterium sp. 255-15]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2216343 5175197 CMM_1961 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222703.1 2215852 D 443906 CDS YP_001222704.1 148273143 5173849 complement(2216380..2217126) 1 NC_009480.1 conserved membrane protein (ZP_00099616.1| COG4200: Uncharacterized protein conserved in bacteria [Desulfitobacterium hafniense]; CAB60257.1| MrsE protein [Bacillus sp. HIL-Y85/54728]; NP_721536.1| putative transporter, trans-membrane domain bacteriocin immunity protein [Streptococcus mutans UA159]). PUTATIVE MEMBRANE PROTEIN INVOLVED IN LANTIBIOTIC IMMUNITY; Function unclear; hypothetical protein 2217126 clvE 5173849 clvE Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222704.1 2216380 R 443906 CDS YP_001222705.1 148273144 5174003 complement(2217132..2217884) 1 NC_009480.1 conserved membrane protein (ZP_00099615.1| COG1277: ABC-type transport system involved in multi-copper enzyme maturation, permease component [Desulfitobacterium hafniense]; CAB60256.1| MrsG protein [Bacillus sp. HIL-Y85/54728]). PUTATIVELY INVOLVED IN IMMUNITY TO LANTIBIOTICS; Specificity unclear; hypothetical protein 2217884 clvG 5174003 clvG Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222705.1 2217132 R 443906 CDS YP_001222706.1 148273145 5172928 complement(2217881..2218780) 1 NC_009480.1 putative ABC transporter, ATP-binding protein (CAB60255.1| MrsF protein [Bacillus sp. HIL-Y85/54728]; ZP_00099614.1| COG1131: ABC-type multidrug transport system, ATPase component [Desulfitobacterium hafniense]). PUTATIVELY INVOLVED IN IMMUNITY TO LANTIBIOTIC. pfam00005,ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter, ATP-binding protein 2218780 clvF 5172928 clvF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001222706.1 2217881 R 443906 CDS YP_001222707.1 148273146 5173690 complement(2218934..2219608) 1 NC_009480.1 putative two-component system, response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00227053.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF LANTIOTIC pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator 2219608 clvR 5173690 clvR Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001222707.1 2218934 R 443906 CDS YP_001222708.1 148273147 5172957 complement(2219605..2220741) 1 NC_009480.1 putative two-component system, sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00228428.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]). PUTATIVELY INVOLVED IN BIOSYNTHESIS OF LANTIBIOTIC InterPro: Histidine kinase-DNA gyrase B- phytochrome-like ATPase.; Specificity unclear; putative two-component system, sensor kinase 2220741 clvK 5172957 clvK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001222708.1 2219605 R 443906 CDS YP_001222709.1 148273148 5173522 2221103..2221309 1 NC_009480.1 putative lantibiotic (clavicidin) precursor (LANA_ACTLG Lantibiotic actagardine (Gardimycin)). MAY INHIBIT PEPTIDOGLYCAN SYNTHESIS; Function unclear; putative lantibiotic precursor 2221309 clvA 5173522 clvA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lantibiotic precursor YP_001222709.1 2221103 D 443906 CDS YP_001222710.1 148273149 5174819 2221401..2224562 1 NC_009480.1 putative lantibiotic modifying protein (CAB60261.1| MrsM protein [Bacillus sp. HIL-Y85/54728]; CAD60521.1| CinM protein [Streptomyces cinnamoneus]). COULD BE IMPLICATED IN THE PROCESSING OR THE EXPORT PROCESS OF THE LANTIBIOTIC produced by Cmm_fin_1764. pfam05500, NisC,NisC-like family. Lantibiotics are peptide-derived, post-translationally modified antimicrobials produced by several bacterial strains.; Specificity unclear; putative lantibiotic modifying enzyme 2224562 clvM 5174819 clvM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lantibiotic modifying enzyme YP_001222710.1 2221401 D 443906 CDS YP_001222711.1 148273150 5173587 complement(2224627..2225943) 1 NC_009480.1 hypothetical protein containing PASTA domain pfam03793, PASTA, PASTA domain. This domain is found at the C termini of several Penicillin-binding proteins and bacterial serine/threonine kinases. It binds the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine - the PBP transpeptidase substrate. InterPro: Proline-rich region.; Family membership; hypothetical protein 2225943 5173587 CMM_1969 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222711.1 2224627 R 443906 CDS YP_001222712.1 148273151 5174054 complement(2226073..2226537) 1 NC_009480.1 putative endonuclease (P50186|VSN1_NOCAE NaeI very-short-patch-repair endonuclease (V.NaeI); ZP_00149287.2| COG3727: DNA G:T-mismatch repair endonuclease [Methanococcoides burtonii DSM 6242]; ZP_00228987.1| COG3727: DNA G:T-mismatch repair endonuclease [Kineococcus radiotolerans SRS30216]). cd00221, Vsr, Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches. vsr: DNA mismatch endonuclease (vsr).; Specificity unclear; putative patch repair endonuclease 2226537 5174054 CMM_1970 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative patch repair endonuclease YP_001222712.1 2226073 R 443906 CDS YP_001222713.1 148273152 5174186 complement(2226747..2228012) 1 NC_009480.1 hypothetical protein 2228012 5174186 CMM_1971 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222713.1 2226747 R 443906 CDS YP_001222714.1 148273153 5174166 complement(2228593..2229132) 1 NC_009480.1 hypothetical membrane protein (NP_789466.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Hypothetical protein; hypothetical protein 2229132 5174166 CMM_1972 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222714.1 2228593 R 443906 CDS YP_001222715.1 148273154 5174933 2229419..2230750 1 NC_009480.1 putative acyl-CoA dehydrogenase (ZP_00057322.1| COG1960: Acyl-CoA dehydrogenases [Thermobifida fusca]; XP_407376.1| hypothetical protein AN3239.2 [Aspergillus nidulans FGSC A4]; ZP_00226657.1| COG1960: Acyl-CoA dehydrogenases [Kineococcus radiotolerans SRS30216]).; Specificity unclear; putative acyl-CoA dehydrogenase 2230750 5174933 CMM_1973 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA dehydrogenase YP_001222715.1 2229419 D 443906 CDS YP_001222716.1 148273155 5174574 complement(2230864..2232372) 1 NC_009480.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2232372 engA 5174574 engA Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP-binding protein EngA YP_001222716.1 2230864 R 443906 CDS YP_001222717.1 148273156 5175550 complement(2232412..2233140) 1 NC_009480.1 putative cytidylate kinase (Cytidine monophosphate kinase) (YP_061643.1| cytidylate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827698.1| putative cytidylate kinase [Streptomyces avermitilis MA-4680]). pfam02224, Cytidylate_kin, Cytidylate kinase. InterPro: Cytidylate kinase.; High confidence in function and specificity; putative cytidylate kinase 2233140 cmkA 5175550 cmkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cytidylate kinase YP_001222717.1 2232412 R 443906 CDS YP_001222718.1 148273157 5175445 complement(2233137..2234213) 1 NC_009480.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 2234213 5175445 CMM_1976 Clavibacter michiganensis subsp. michiganensis NCPPB 382 prephenate dehydrogenase YP_001222718.1 2233137 R 443906 CDS YP_001222719.1 148273158 5174444 complement(2234252..2235112) 1 NC_009480.1 putative pseudouridine synthase (YP_061641.1| RNA pseudouridine synthase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056094.1| ribosomal large subunit pseudouridine synthase B [Propionibacterium acnes KPA171202]). pfam01479, S4, S4 domain. pfam00849,PseudoU_synth_2, RNA pseudouridylate synthase. Members of this family are involved in modifying bases in RNA molecules.; Family membership; putative pseudouridine synthase 2235112 rluA 5174444 rluA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pseudouridine synthase YP_001222719.1 2234252 R 443906 CDS YP_001222720.1 148273159 5173928 complement(2235096..2235707) 1 NC_009480.1 conserved hypothetical protein, putative transcriptional regulator (YP_061640.1| Hypothetical protein Lxx05690 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB52833.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam04079, DUF387,Putative transcriptional regulators (Ypuh-like). This family of conserved bacterial proteins are thought to possibly be helix-turn-helix type transcriptional regulators. potential Segregation and condensation protein B; Function unclear; putative transcriptional regulator 2235707 5173928 CMM_1978 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001222720.1 2235096 R 443906 CDS YP_001222721.1 148273160 5174756 complement(2235697..2236494) 1 NC_009480.1 conserved hypothetical protein (YP_061639.1| Hypothetical protein Lxx05680 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00057587.1| COG1354: Uncharacterized conserved protein [Thermobifida fusca]; NP_626041.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). InterPro: DUF173 pfam02616, DUF173,Uncharacterised ACR, COG1354.; Function unclear; hypothetical protein 2236494 5174756 CMM_1979 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222721.1 2235697 R 443906 CDS YP_001222722.1 148273161 5173732 complement(2236550..2237434) 1 NC_009480.1 putative ATPase involved in partitioning (YP_061638.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827684.1| putative partitioning or sporulation protein [Streptomyces avermitilis MA-4680]). pfam00991, ParA, ParA family ATPase. InterPro: ParA family ATPase; Function unclear; putative ATPase involved in partitioning 2237434 5173732 CMM_1980 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase involved in partitioning YP_001222722.1 2236550 R 443906 CDS YP_001222723.1 148273162 5175373 complement(2237504..2238490) 1 NC_009480.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 2238490 xerD 5175373 xerD Clavibacter michiganensis subsp. michiganensis NCPPB 382 site-specific tyrosine recombinase XerD YP_001222723.1 2237504 R 443906 CDS YP_001222724.1 148273163 5174150 complement(2238487..2239164) 1 NC_009480.1 putative NTP pyrophosphatase (YP_061636.1| NUDIX hydrolase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827681.1| putative ADP-ribose pyrophosphatase [Streptomyces avermitilis MA-4680]). pfam00293, NUDIX,NUDIX domain.; Function unclear; putative NTP pyrophosphatase 2239164 5174150 CMM_1982 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphatase YP_001222724.1 2238487 R 443906 CDS YP_001222725.1 148273164 5174058 complement(2239161..2240903) 1 NC_009480.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2240903 pyrG 5174058 pyrG Clavibacter michiganensis subsp. michiganensis NCPPB 382 CTP synthetase YP_001222725.1 2239161 R 443906 CDS YP_001222726.1 148273165 5175407 complement(2240977..2242692) 1 NC_009480.1 putative DNA repair protein (Recombination protein N) (YP_061634.1| DNA repair protein RecN [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294027.1| COG0497: ATPase involved in DNA repair [Thermobifida fusca]). pfam02463,SMC_N, RecF/RecN/SMC N terminal domain. This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini,and two extended coiled-coil domains separated by a hinge in the middle. pfam02483, SMC_C, SMC family, C-terminal domain. recN: DNA repair protein RecN; High confidence in function and specificity; putative DNA repair protein 2242692 recN 5175407 recN Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA repair protein YP_001222726.1 2240977 R 443906 CDS YP_001222727.1 148273166 5175487 complement(2242685..2243602) 1 NC_009480.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2243602 ppnK 5175487 ppnK Clavibacter michiganensis subsp. michiganensis NCPPB 382 inorganic polyphosphate/ATP-NAD kinase YP_001222727.1 2242685 R 443906 CDS YP_001222728.1 148273167 5174256 complement(2243608..2244486) 1 NC_009480.1 putative rRNA methyltransferase (ZP_00294025.1| COG1189: Predicted rRNA methylase [Thermobifida fusca]; AAN24854.1| hemolysin-like protein with S4 domain found in bacteria and plants [Bifidobacterium longum NCC2705]). pfam01479, S4, S4 domain. Interpro: S4 domain. Interpro: Ribosomal RNA methyltransferase RrmJ/FtsJ.; Function unclear; hypothetical protein 2244486 5174256 CMM_1986 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222728.1 2243608 R 443906 CDS YP_001222729.1 148273168 5175624 complement(2244479..2244688) 1 NC_009480.1 hypothetical protein (YP_061679.1| Hypothetical protein Lxx06150 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2244688 5175624 CMM_1987 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222729.1 2244479 R 443906 CDS YP_001222730.1 148273169 5175483 complement(2244698..2245738) 1 NC_009480.1 conserved hypothetical protein, putative hydrolase (YP_061321.1| 4-nitrophenylphosphatase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_626059.1| hypothetical protein SCO1788 [Streptomyces coelicolor A3(2)]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase 2245738 5175483 CMM_1988 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001222730.1 2244698 R 443906 CDS YP_001222731.1 148273170 5175668 complement(2245728..2246708) 1 NC_009480.1 conserved hypothetical protein (ZP_00294017.1| COG0457: FOG: TPR repeat [Thermobifida fusca]; CAF21419.1| conserved hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 2246708 5175668 CMM_1989 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222731.1 2245728 R 443906 CDS YP_001222732.1 148273171 5173403 complement(2253555..2254859) 1 NC_009480.1 tyrosyl-tRNA synthetase (Tyrosine-tRNA ligase) (YP_061678.1| tyrosyl-tRNA synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827635.1| putative tyrosyl-tRNA synthetase [Streptomyces avermitilis MA-4680]). pfam00579, tRNA-synt_1b, tRNA synthetases class I (W and Y). pfam01479, S4, S4 domain.; High confidence in function and specificity; hypothetical protein 2254859 tyrS 5173403 tyrS Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222732.1 2253555 R 443906 CDS YP_001222733.1 148273172 5172970 2255079..2255786 1 NC_009480.1 conserved hypothetical protein, putative DNA-binding protein (YP_061677.1| Hypothetical protein Lxx06130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_939627.1| Putative DNA-binding protein [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 2255786 5172970 CMM_1991 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222733.1 2255079 D 443906 CDS YP_001222734.1 148273173 5174776 2255783..2256382 1 NC_009480.1 putative membrane protein (YP_061675.1| Hypothetical protein Lxx06110 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_721449.1| conserved hypothetical protein, SatE [Streptococcus mutans UA159]).; hypothetical protein 2256382 5174776 CMM_1992 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222734.1 2255783 D 443906 CDS YP_001222735.1 148273174 5175290 complement(2256413..2257027) 1 NC_009480.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 2257027 5175290 CMM_1993 Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-methyladenine DNA glycosylase YP_001222735.1 2256413 R 443906 CDS YP_001222736.1 148273175 5175839 complement(2257035..2257172) 1 NC_009480.1 hypothetical protein 2257172 5175839 CMM_1994 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222736.1 2257035 R 443906 CDS YP_001222737.1 148273176 5175086 complement(2257169..2258662) 1 NC_009480.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 2258662 argH 5175086 argH Clavibacter michiganensis subsp. michiganensis NCPPB 382 argininosuccinate lyase YP_001222737.1 2257169 R 443906 CDS YP_001222738.1 148273177 5173952 complement(2258667..2259905) 1 NC_009480.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 2259905 argG 5173952 argG Clavibacter michiganensis subsp. michiganensis NCPPB 382 argininosuccinate synthase YP_001222738.1 2258667 R 443906 CDS YP_001222739.1 148273178 5175478 complement(2259954..2260877) 1 NC_009480.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 2260877 argF 5175478 argF Clavibacter michiganensis subsp. michiganensis NCPPB 382 ornithine carbamoyltransferase YP_001222739.1 2259954 R 443906 CDS YP_001222740.1 148273179 5175273 complement(2261027..2262244) 1 NC_009480.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine aminotransferase 2262244 argD 5175273 argD Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetylornithine aminotransferase YP_001222740.1 2261027 R 443906 CDS YP_001222741.1 148273180 5173913 complement(2262241..2263152) 1 NC_009480.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 2263152 argB 5173913 argB Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetylglutamate kinase YP_001222741.1 2262241 R 443906 CDS YP_001222742.1 148273181 5175093 complement(2263176..2264330) 1 NC_009480.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein 2264330 argJ 5175093 argJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein YP_001222742.1 2263176 R 443906 CDS YP_001222743.1 148273182 5175474 complement(2264327..2265376) 1 NC_009480.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 2265376 argC 5175474 argC Clavibacter michiganensis subsp. michiganensis NCPPB 382 N-acetyl-gamma-glutamyl-phosphate reductase YP_001222743.1 2264327 R 443906 CDS YP_001222744.1 148273183 5174077 complement(2265506..2268049) 1 NC_009480.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2268049 pheT 5174077 pheT Clavibacter michiganensis subsp. michiganensis NCPPB 382 phenylalanyl-tRNA synthetase subunit beta YP_001222744.1 2265506 R 443906 CDS YP_001222745.1 148273184 5174510 complement(2268052..2269089) 1 NC_009480.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2269089 pheS 5174510 pheS Clavibacter michiganensis subsp. michiganensis NCPPB 382 phenylalanyl-tRNA synthetase subunit alpha YP_001222745.1 2268052 R 443906 CDS YP_001222746.1 148273185 5174542 complement(2269218..2270042) 1 NC_009480.1 putative glutamate ABC transpoter, permease component (NP_738457.1| glutamate transporter permease protein GluD [Corynebacterium efficiens YS-314]; NP_823136.1| putative glutamate permease [Streptomyces avermitilis MA-4680]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glutamate ABC transpoter, permease component 2270042 gluD 5174542 gluD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamate ABC transpoter, permease component YP_001222746.1 2269218 R 443906 CDS YP_001222747.1 148273186 5174617 complement(2270039..2270686) 1 NC_009480.1 putative glutamate ABC transpoter, permease component (NP_823137.1| putative glutamate permease [Streptomyces avermitilis MA-4680]; ZP_00293559.1| COG0765: ABC-type amino acid transport system, permease component [Thermobifida fusca]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative glutamate ABC transpoter, permease component 2270686 gluC 5174617 gluC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamate ABC transpoter, permease component YP_001222747.1 2270039 R 443906 CDS YP_001222748.1 148273187 5173167 complement(2270804..2271727) 1 NC_009480.1 putative glutamate ABC transporter, substrate-binding protein (NP_823138.1| putative glutamate periplasmic binding protein [Streptomyces avermitilis MA-4680]; ZP_00293560.1| COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/ domain [Thermobifida fusca]). pfam00497,SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3.; Specificity unclear; putative glutamate ABC transporter, substrate-binding protein 2271727 gluB 5173167 gluB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamate ABC transporter, substrate-binding protein YP_001222748.1 2270804 R 443906 CDS YP_001222749.1 148273188 5175388 complement(2271882..2272670) 1 NC_009480.1 putative glutamate ABC transporter, ATP-binding protein (NP_629902.1| glutamate uptake system ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00293561.1| COG1126: ABC-type polar amino acid transport system,ATPase component [Thermobifida fusca]). InterPro: AAA ATPase superfamily; Specificity unclear; putative glutamate ABC transporter, ATP-binding protein 2272670 gluA 5175388 gluA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutamate ABC transporter, ATP-binding protein YP_001222749.1 2271882 R 443906 CDS YP_001222750.1 148273189 5174375 complement(2272822..2273622) 1 NC_009480.1 putaive rRNA methyltransferase (YP_061662.1| rRNA methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625873.1| putative rRNA methylase [Streptomyces coelicolor A3(2)]). pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet.; Function unclear; putaive rRNA methyltransferase 2273622 5174375 CMM_2008 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putaive rRNA methyltransferase YP_001222750.1 2272822 R 443906 CDS YP_001222751.1 148273190 5174142 complement(2273685..2274077) 1 NC_009480.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2274077 rplT 5174142 rplT Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L20 YP_001222751.1 2273685 R 443906 CDS YP_001222752.1 148273191 5173513 complement(2274124..2274318) 1 NC_009480.1 50S ribosomal protein L35 (YP_062721.1| 50S ribosomal protein L35 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787293.1| 50S ribosomal protein L35 [Tropheryma whipplei str. Twist]). pfam01632,Ribosomal_L35p, Ribosomal protein L35.; High confidence in function and specificity; 50S ribosomal protein L35 2274318 rpmI 5173513 rpmI Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L35 YP_001222752.1 2274124 R 443906 CDS YP_001222753.1 148273192 5174138 complement(2274311..2274730) 1 NC_009480.1 translation initiation factor IF-3 (YP_062722.1| translation initiation factor IF-3 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625876.1| putative translation initiation factor IF-3 [Streptomyces coelicolor A3(2)]). IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. pfam05198, IF3_N, Translation initiation factor IF-3, N-terminal domain. pfam00707,IF3_C, Translation initiation factor IF-3, C-terminal domain.; High confidence in function and specificity; translation initiation factor IF-3 2274730 infC 5174138 infC Clavibacter michiganensis subsp. michiganensis NCPPB 382 translation initiation factor IF-3 YP_001222753.1 2274311 R 443906 CDS YP_001222754.1 148273193 5174611 2275284..2275769 1 NC_009480.1 hypothetical protein (ZP_00226864.1| COG0468: RecA/RadA recombinase [Kineococcus radiotolerans SRS30216]; NP_827912.1| hypothetical protein SAV6736 [Streptomyces avermitilis MA-4680]).; hypothetical protein 2275769 5174611 CMM_2012 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222754.1 2275284 D 443906 CDS YP_001222755.1 148273194 5174569 complement(2275809..2276576) 1 NC_009480.1 hypothetical protein (NP_625878.1| hypothetical protein SCI35.24c [Streptomyces coelicolor A3(2)]; ZP_00291747.1| hypothetical protein Tfus02002786 [Thermobifida fusca]).; Function unclear; hypothetical protein 2276576 5174569 CMM_2013 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222755.1 2275809 R 443906 CDS YP_001222756.1 148273195 5175912 complement(2276573..2277322) 1 NC_009480.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis; phosphoribosyl isomerase A 2277322 hisA 5175912 hisA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosyl isomerase A YP_001222756.1 2276573 R 443906 CDS YP_001222757.1 148273196 5173197 complement(2277386..2278027) 1 NC_009480.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2278027 hisH 5173197 hisH Clavibacter michiganensis subsp. michiganensis NCPPB 382 imidazole glycerol phosphate synthase subunit HisH YP_001222757.1 2277386 R 443906 CDS YP_001222758.1 148273197 5174374 complement(2278024..2278632) 1 NC_009480.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2278632 hisB 5174374 hisB Clavibacter michiganensis subsp. michiganensis NCPPB 382 imidazoleglycerol-phosphate dehydratase YP_001222758.1 2278024 R 443906 CDS YP_001222759.1 148273198 5173295 complement(2278745..2279143) 1 NC_009480.1 conserved membrane protein (ZP_00292498.1| COG0739: Membrane proteins related to metalloendopeptidases [Thermobifida fusca]; NP_337294.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]). weak similarity to: pfam01476, LysM, LysM domain. It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein 2279143 5173295 CMM_2017 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222759.1 2278745 R 443906 CDS YP_001222760.1 148273199 5175173 2279505..2280185 1 NC_009480.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 2280185 lexA 5175173 lexA Clavibacter michiganensis subsp. michiganensis NCPPB 382 LexA repressor YP_001222760.1 2279505 D 443906 CDS YP_001222761.1 148273200 5173642 complement(2280270..2281835) 1 NC_009480.1 putative GTP-binding protein (NP_629920.1| conserved hypothetical protein SC4H2.17 [Streptomyces coelicolor A3(2)]; ZP_00293571.1| COG2262: GTPases [Thermobifida fusca]). pfam00071, Ras, Ras family. Includes sub-families Ras, Rab, Rac, Ral, Ran, Rap Ypt1 and more. Shares P-loop motif with GTP_EFTU, arf and myosin_head.; Function unclear; putative GTP-binding protein 2281835 hflX 5173642 hflX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative GTP-binding protein YP_001222761.1 2280270 R 443906 CDS YP_001222762.1 148273201 5173133 2281876..2282502 1 NC_009480.1 putative rRNA methylase (ZP_00226409.1| COG2813: 16S RNA G1207 methylase RsmC [Kineococcus radiotolerans SRS30216]; ZP_00120705.1| COG2813: 16S RNA G1207 methylase RsmC [Bifidobacterium longum DJO10A]). pfam01170, UPF0020, Putative RNA methylase family UPF0020.; Conserved hypothetical protein; hypothetical protein 2282502 5173133 CMM_2020 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222762.1 2281876 D 443906 CDS YP_001222763.1 148273202 5174176 complement(2282551..2283429) 1 NC_009480.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 2283429 dapF 5174176 dapF Clavibacter michiganensis subsp. michiganensis NCPPB 382 diaminopimelate epimerase YP_001222763.1 2282551 R 443906 CDS YP_001222764.1 148273203 5174179 complement(2283439..2284362) 1 NC_009480.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 2284362 miaA 5174179 miaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 tRNA delta(2)-isopentenylpyrophosphate transferase YP_001222764.1 2283439 R 443906 CDS YP_001222765.1 148273204 5175856 complement(2284359..2285945) 1 NC_009480.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2285945 miaB 5175856 miaB Clavibacter michiganensis subsp. michiganensis NCPPB 382 (dimethylallyl)adenosine tRNA methylthiotransferase YP_001222765.1 2284359 R 443906 CDS YP_001222766.1 148273205 5173198 complement(2285996..2286568) 1 NC_009480.1 putative recX, regulatory protein for recA activity (O50488|RECX_STRCO Regulatory protein recX; ZP_00058957.1| COG2137: Uncharacterized protein conserved in bacteria [Thermobifida fusca]). pfam02631, RecX, RecX family. RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.; Conserved hypothetical protein; hypothetical protein 2286568 recX 5173198 recX Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222766.1 2285996 R 443906 CDS YP_001222767.1 148273206 5175940 complement(2287165..2288253) 1 NC_009480.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2288253 recA 5175940 recA Clavibacter michiganensis subsp. michiganensis NCPPB 382 recombinase A YP_001222767.1 2287165 R 443906 CDS YP_001222768.1 148273207 5173414 complement(2288536..2288769) 1 NC_009480.1 conserved hypothetical protein (NP_961784.1| hypothetical protein MAP2850c [Mycobacterium avium subsp. paratuberculosis str. k10]; BAB99349.1| Hypothetical protein [Corynebacterium glutamicum ATCC 13032]).; hypothetical protein 2288769 5173414 CMM_2026 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222768.1 2288536 R 443906 CDS YP_001222769.1 148273208 5173860 complement(2288846..2289154) 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (ZP_00293549.1| COG1396: Predicted transcriptional regulators [Thermobifida fusca]; H70878 probable regulator - Mycobacterium tuberculosis (strain H37RV)). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 2289154 5173860 CMM_2027 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001222769.1 2288846 R 443906 CDS YP_001222770.1 148273209 5173810 complement(2289294..2289818) 1 NC_009480.1 conserved hypothetical protein (ZP_00047717.1| COG1546: Uncharacterized protein (competence- and mitomycin-induced) [Magnetospirillum magnetotacticum]; NP_629879.1| conserved hypothetical protein SC7C7.09 [Streptomyces coelicolor A3(2)]). pfam02464, CinA,Competence-damaged protein. InterPro: Competence-damaged protein cinA_cterm: competence/damage-inducible p; Function unclear; hypothetical protein 2289818 5173810 CMM_2028 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222770.1 2289294 R 443906 CDS YP_001222771.1 148273210 5174975 complement(2289815..2290441) 1 NC_009480.1 putative CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyl- transferase (NP_629878.1| phosphatidylglycerophosphate synthase [Streptomyces coelicolor A3(2)]; ZP_00058965.1| COG0558: Phosphatidyl-glycerophosphate synthase [Thermobifida fusca]). May catalyze the committed step to the synthesis of the acidic phospholipids. pfam01066, CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase. InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Specificity unclear; hypothetical protein 2290441 pgsA 5174975 pgsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222771.1 2289815 R 443906 CDS YP_001222772.1 148273211 5174649 complement(2290445..2293300) 1 NC_009480.1 putative DNA translocase ftsK (Q82K93|FTSK_STRAW DNA translocase ftsK; ZP_00058968.1| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Thermobifida fusca]). DNA motor protein which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it. InterPro: FtsK/SpoIIIE family pfam01580, FtsK_SpoIIIE,FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif.; High confidence in function and specificity; cell division protein 2293300 ftsK 5174649 ftsK Clavibacter michiganensis subsp. michiganensis NCPPB 382 cell division protein YP_001222772.1 2290445 R 443906 CDS YP_001222773.1 148273212 5174069 complement(2293369..2294601) 1 NC_009480.1 putative ABC transporter, permease component (ZP_00198031.1| COG0577: ABC-type antimicrobial peptide transport system, permease component [Kineococcus radiotolerans SRS30216]; ZP_00048178.2| COG0577: ABC-type antimicrobial peptide transport system, permease component [Magnetospirillum magnetotacticum]). pfam02687, FtsX,Predicted permease. This is a family of predicted permeases and hypothetical transmembrane proteins).; Specificity unclear; putative ABC transporter, permease component 2294601 5174069 CMM_2031 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, permease component YP_001222773.1 2293369 R 443906 CDS YP_001222774.1 148273213 5174557 complement(2294598..2295305) 1 NC_009480.1 putative ABC transporter, ATPase component (ZP_00225680.1| COG1136: ABC-type antimicrobial peptide transport system, ATPase component [Kineococcus radiotolerans SRS30216]; NP_811407.1| ABC transporter,ATP-binding protein [Bacteroides thetaiotaomicron VPI-5482]). InterPro: AAA ATPase superfamily pfam00005,ABC_tran, ABC transporter.; Specificity unclear; putative ABC transporter, ATPase component 2295305 5174557 CMM_2032 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATPase component YP_001222774.1 2294598 R 443906 CDS YP_001222775.1 148273214 5175903 complement(2295302..2296327) 1 NC_009480.1 conserved hypothetical protein, weak similarity to multidrug export proteins (NP_903507.1| probable multidrug efflux membrane protein [Chromobacterium violaceum ATCC 12472]; NP_251079.1| conserved hypothetical protein [Pseudomonas aeruginosa PA01]).; Function unclear; hypothetical protein 2296327 5175903 CMM_2033 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222775.1 2295302 R 443906 CDS YP_001222776.1 148273215 5175138 complement(2296540..2298216) 1 NC_009480.1 putative hydrolase, metallo-beta-lactamase superfamily (NP_823691.1| putative hydrolase of the metallo-beta-lactamase superfamily [Streptomyces avermitilis MA-4680]; NP_629870.1| conserved hypothetical protein SC9A10.09 [Streptomyces coelicolor A3(2)]). pfam00753, Lactamase_B, Metallo-beta-lactamase superfamily.; Function unclear; metallo-beta-lactamase family hydrolase 2298216 5175138 CMM_2034 Clavibacter michiganensis subsp. michiganensis NCPPB 382 metallo-beta-lactamase family hydrolase YP_001222776.1 2296540 R 443906 CDS YP_001222777.1 148273216 5175185 complement(2298275..2299249) 1 NC_009480.1 putative dihydrodipicolinate synthase (O86841|DAP1_STRCO Dihydrodipicolinate synthase 1 (DHDPS 1); ZP_00225471.1| COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Kineococcus radiotolerans SRS30216]). pfam00701, DHDPS,Dihydrodipicolinate synthetase family. InterPro: Dihydrodipicolinate synthetase.; High confidence in function and specificity; putative dihydrodipicolinate synthase 2299249 dapA 5175185 dapA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dihydrodipicolinate synthase YP_001222777.1 2298275 R 443906 CDS YP_001222778.1 148273217 5175089 2299389..2300642 1 NC_009480.1 hypothetical protein 2300642 5175089 CMM_2036 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222778.1 2299389 D 443906 CDS YP_001222779.1 148273218 5175325 complement(2300672..2301463) 1 NC_009480.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 2301463 thyX 5175325 thyX Clavibacter michiganensis subsp. michiganensis NCPPB 382 FAD-dependent thymidylate synthase YP_001222779.1 2300672 R 443906 CDS YP_001222780.1 148273219 5174987 2301571..2302491 1 NC_009480.1 putative nucleoside-diphosphate sugar epimerase (ZP_00050154.1| COG1090: Predicted nucleoside-diphosphate sugar epimerase [Magnetospirillum magnetotacticum]; NP_827190.1| putative NAD dependent epimerase/dehydratase family [Streptomyces avermitilis MA-4680]).; Function unclear; putative nucleoside-diphosphate sugar epimerase 2302491 5174987 CMM_2038 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate sugar epimerase YP_001222780.1 2301571 D 443906 CDS YP_001222781.1 148273220 5175455 complement(2302512..2302961) 1 NC_009480.1 conserved membrane protein (P46830|YDAB_MYCBO Hypothetical 19.3 kDa protein in dapB 3'region (ORF Z); NP_629865.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 2302961 5175455 CMM_2039 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222781.1 2302512 R 443906 CDS YP_001222782.1 148273221 5175449 complement(2302961..2303794) 1 NC_009480.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 2303794 dapB 5175449 dapB Clavibacter michiganensis subsp. michiganensis NCPPB 382 dihydrodipicolinate reductase YP_001222782.1 2302961 R 443906 CDS YP_001222783.1 148273222 5175123 complement(2303854..2304456) 1 NC_009480.1 putative phosphoglycerate mutase (NP_631275.1| putative phosphoglycerate mutase [Streptomyces coelicolor A3(2)]; Q8ZJU8|GPMB_SALTY Probable phosphoglycerate mutase gpmB (Phosphoglyceromutase) (PGAM)). pfam00300,PGAM, Phosphoglycerate mutase family.; Specificity unclear; hypothetical protein 2304456 gmpB 5175123 gmpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222783.1 2303854 R 443906 CDS YP_001222784.1 148273223 5175052 complement(2304465..2305820) 1 NC_009480.1 putative metallopeptidase, family M16 (ZP_00227821.1| COG0612: Predicted Zn-dependent peptidases [Kineococcus radiotolerans SRS30216]; O86835|YLD8_STRCO Hypothetical zinc protease SCO5738). pfam00675,Peptidase_M16, Insulinase (Peptidase family M16). pfam05193, Peptidase_M16_C, Peptidase M16 inactive domain. InterPro: Insulinase family (Peptidase family M16).; Specificity unclear; M16 family metallopeptidase 2305820 pepR 5175052 pepR Clavibacter michiganensis subsp. michiganensis NCPPB 382 M16 family metallopeptidase YP_001222784.1 2304465 R 443906 CDS YP_001222785.1 148273224 5175042 complement(2305884..2306792) 1 NC_009480.1 hypothetical protein (ZP_00412660.1| hypothetical protein ArthDRAFT_2763 [Arthrobacter sp. FB24]; ZP_00658097.1| hypothetical protein NocaDRAFT_2263 [Nocardioides sp. JS614]).; hypothetical protein 2306792 5175042 CMM_2043 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222785.1 2305884 R 443906 CDS YP_001222786.1 148273225 5175557 complement(2307500..2308606) 1 NC_009480.1 putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 2308606 5175557 CMM_2044 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222786.1 2307500 R 443906 CDS YP_001222787.1 148273226 5175472 2309060..2309590 1 NC_009480.1 conserved hypothetical protein, putative phospholipid-binding protein (NP_628200.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_960819.1| hypothetical protein MAP1885c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam01161, PBP,Phosphatidylethanolamine-binding protein.; Function unclear; hypothetical protein 2309590 5175472 CMM_2045 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222787.1 2309060 D 443906 CDS YP_001222788.1 148273227 5175536 2309613..2309999 1 NC_009480.1 hypothetical protein 2309999 5175536 CMM_2046 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222788.1 2309613 D 443906 CDS YP_001222789.1 148273228 5175509 complement(2310069..2312342) 1 NC_009480.1 putative polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (ZP_00227822.1| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Kineococcus radiotolerans SRS30216]; NP_787549.1| polyribonucleotide nucleotidyltransferase [Tropheryma whipplei str. Twist]). pfam01138, RNase_PH, 3' exoribonuclease family, domain 1. This family includes 3'-5' exoribonucleases (twice). pfam03725, RNase_PH_C, 3' exoribonuclease family, domain 2 (twice). pfam03726,PNPase, Polyribonucleotide nucleotidyltransferase, RNA binding domain. pfam00575, S1, S1 RNA binding domain. The S1 domain occurs in a wide range of RNA associated proteins.; High confidence in function and specificity; polynucleotide phosphorylase/polyadenylase 2312342 pnpA 5175509 pnpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 polynucleotide phosphorylase/polyadenylase YP_001222789.1 2310069 R 443906 CDS YP_001222790.1 148273229 5173271 complement(2312820..2313089) 1 NC_009480.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2313089 rpsO 5173271 rpsO Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S15 YP_001222790.1 2312820 R 443906 CDS YP_001222791.1 148273230 5175217 2313325..2314626 1 NC_009480.1 putative MFS permease (ZP_00190511.2| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]; NP_599375.1| permease of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]).; Specificity unclear; putative MFS permease 2314626 5175217 CMM_2049 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001222791.1 2313325 D 443906 CDS YP_001222792.1 148273231 5175585 2314653..2315384 1 NC_009480.1 conserved hypothetical protein (ZP_00226454.1| hypothetical protein Krad06003337 [Kineococcus radiotolerans SRS30216]; NP_739263.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; hypothetical protein 2315384 5175585 CMM_2050 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222792.1 2314653 D 443906 CDS YP_001222793.1 148273232 5175562 complement(2315628..2317202) 1 NC_009480.1 putative dicarboxylate transporter, DASS family (NP_348217.1| 2-oxoglutarate/malate translocator [Clostridium acetobutylicum ATCC 824]; ZP_00322706.1| COG0471: Di- and tricarboxylate transporters [Pediococcus pentosaceus ATCC 25745])., pfam00939, Na_sulph_symp,Sodium:sulfate symporter transmembrane region.; Specificity unclear; 2-oxoglutarate/malate translocator 2317202 5175562 CMM_2051 Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-oxoglutarate/malate translocator YP_001222793.1 2315628 R 443906 CDS YP_001222794.1 148273233 5175627 complement(2317307..2319583) 1 NC_009480.1 putative ATP-dependent DNA helicase (ZP_00226623.1| COG3973: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]; ZP_00120699.1| COG3973: Superfamily I DNA and RNA helicases [Bifidobacterium longum DJO10A]). InterPro: UvrD/REP helicase pfam00580,UvrD-helicase, UvrD/REP helicase.; Function unclear; putative ATP-dependent DNA helicase 2319583 5175627 CMM_2052 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001222794.1 2317307 R 443906 CDS YP_001222795.1 148273234 5175577 complement(2319688..2320176) 1 NC_009480.1 putative membrane protein (ZP_00322542.1| COG4767: Glycopeptide antibiotics resistance protein [Pediococcus pentosaceus ATCC 25745]; NP_940629.1| Conserved integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam04892, VanZ, VanZ like family.; Hypothetical protein; hypothetical protein 2320176 5175577 CMM_2053 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222795.1 2319688 R 443906 CDS YP_001222796.1 148273235 5175133 2320419..2321678 1 NC_009480.1 putative methionine synthase II (cobalamin-independent), 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (ZP_00226646.1| COG0620: Methionine synthase II (cobalamin-independent); NP_601330.1| methionine synthase II [Corynebacterium glutamicum ATCC 13032]). , pfam01717, Methionine_synt,Methionine synthase, vitamin-B12 independent.; High confidence in function and specificity; 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase 2321678 metE2 5175133 metE2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase YP_001222796.1 2320419 D 443906 CDS YP_001222797.1 148273236 5173678 complement(2321683..2322210) 1 NC_009480.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 2322210 aptA 5173678 aptA Clavibacter michiganensis subsp. michiganensis NCPPB 382 adenine phosphoribosyltransferase YP_001222797.1 2321683 R 443906 CDS YP_001222798.1 148273237 5175053 2322317..2323048 1 NC_009480.1 conserved membrane protein (NP_824217.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00292627.1| hypothetical protein Tfus02001905 [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein 2323048 5175053 CMM_2056 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222798.1 2322317 D 443906 CDS YP_001222799.1 148273238 5175611 complement(2323130..2323963) 1 NC_009480.1 putative 2,5-diketo-D-gluconic acid reductase (NP_631409.1| oxidoreductase. [Streptomyces coelicolor A3(2)]; A45961 2,5-diketo-D-gluconate reductase (EC 1.1.1.-) - Corynebacterium sp. (strain SHS752001)). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity.; Specificity unclear; putative 2,5-diketo-D-gluconic acid reductase 2323963 5175611 CMM_2057 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2,5-diketo-D-gluconic acid reductase YP_001222799.1 2323130 R 443906 CDS YP_001222800.1 148273239 5175698 complement(2323986..2324600) 1 NC_009480.1 putative lipoprotein signal peptidase (Signal peptidase II) (CAF20476.1| LIPOPROTEIN SIGNAL PEPTIDASE [Corynebacterium glutamicum ATCC 13032]; H70760 probable lipoprotein signal peptidase - Mycobacterium tuberculosis (strain H37RV)). This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity). lspA: lipoprotein signal peptidase pfam01252,Peptidase_A8, Signal peptidase (SPase) II.; Specificity unclear; putative lipoprotein signal peptidase 2324600 lspA 5175698 lspA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lipoprotein signal peptidase YP_001222800.1 2323986 R 443906 CDS YP_001222801.1 148273240 5175300 complement(2324610..2325137) 1 NC_009480.1 hypothetical protein (weak similaritiy to NP_625313.1| putative lipoprotein [Streptomyces coelicolor A3(2)]; NP_822599.1| hypothetical protein [Streptomyces avermitilis MA-4680]).; hypothetical protein 2325137 5175300 CMM_2059 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222801.1 2324610 R 443906 CDS YP_001222802.1 148273241 5175620 complement(2325185..2325751) 1 NC_009480.1 putative cysteine peptidase, family C56 (NP_866072.1| proteinase I [Pirellula sp. 1]; ZP_00056842.1| COG0693: Putative intracellular protease/amidase [Thermobifida fusca]). pfam01965, DJ-1_PfpI, DJ-1/PfpI family. The family includes the protease PfpI. This domain is also found in transcriptional regulators.; Specificity unclear; cysteine peptidase family protein C56 2325751 5175620 CMM_2060 Clavibacter michiganensis subsp. michiganensis NCPPB 382 cysteine peptidase family protein C56 YP_001222802.1 2325185 R 443906 CDS YP_001222803.1 148273242 5175745 complement(2325834..2326712) 1 NC_009480.1 conserved hypothetical protein (ZP_00212210.1| COG3386: Gluconolactonase [Burkholderia cepacia R18194]; NP_925815.1| hypothetical protein gll2869 [Gloeobacter violaceus]) in eukaryotes a Ca-binding regulatory protein (pfam03758, SMP-30, Senescence marker protein-30 (SMP-30). SMP-30, also known as regucalcin, seems to play a critical role in the highly differentiated functions of the liver and kidney and to exert a major impact on Ca2+ homeostasis).; Family membership; hypothetical protein 2326712 5175745 CMM_2061 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222803.1 2325834 R 443906 CDS YP_001222804.1 148273243 5175720 2326956..2327516 1 NC_009480.1 putative DNA-binding ferritin-like protein (ZP_00226002.1| COG0783: DNA-binding ferritin-like protein (oxidative damage protectant) [Kineococcus radiotolerans SRS30216]; NP_822781.1| hypothetical protein SAV1605 [Streptomyces avermitilis MA-4680]). pfam00210, Ferritin,Ferritin-like domain. This family contains ferritins and other ferritin-like proteins such as members of the DPS family and bacterioferritins.; Function unclear; putative DNA-binding ferritin-like protein 2327516 dpsB 5175720 dpsB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-binding ferritin-like protein YP_001222804.1 2326956 D 443906 CDS YP_001222805.1 148273244 5173770 2327638..2328435 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_642446.1| 3-ketoacyl-acyl carrier protein reductase [Xanthomonas axonopodis pv. citri str. 306]; ZP_00052290.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Magnetospirillum magnetotacticum]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; short chain dehydrogenase/oxidoreductase 2328435 5173770 CMM_2063 Clavibacter michiganensis subsp. michiganensis NCPPB 382 short chain dehydrogenase/oxidoreductase YP_001222805.1 2327638 D 443906 CDS YP_001222806.1 148273245 5175754 2328435..2328644 1 NC_009480.1 hypothetical protein (NP_631705.1| hypothetical protein [Streptomyces coelicolor A3(2)]; NP_883707.1| conserved hypothetical protein Bordetella parapertussis 12822]).; hypothetical protein 2328644 5175754 CMM_2064 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222806.1 2328435 D 443906 CDS YP_001222807.1 148273246 5175733 2328724..2329971 1 NC_009480.1 putative two-component system sensor kinase (NP_825857.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00228428.1| COG4585: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]). InterPro: Histidine kinase- DNA gyrase B- phytochrome-like ATPase pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2329971 5175733 CMM_2065 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001222807.1 2328724 D 443906 CDS YP_001222808.1 148273247 5175942 2329968..2330630 1 NC_009480.1 putative two-component system response regulator (NP_625929.1| putative two-component response regulator [Streptomyces coelicolor A3(2)]; ZP_00229057.1| COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Kineococcus radiotolerans SRS30216]). InterPro: Response regulator receiver domain pfam00072, Response_reg, Response regulator receiver domain. pfam00196, GerE, Bacterial regulatory proteins,luxR family.; Specificity unclear; putative two-component system response regulator 2330630 5175942 CMM_2066 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001222808.1 2329968 D 443906 CDS YP_001222809.1 148273248 5175871 complement(2330668..2332107) 1 NC_009480.1 putative D-alanyl-D-alanine carboxypeptidase (penicillin binding protein precursor) (NP_338276.1| D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family [Mycobacterium tuberculosis CDC1551]; ZP_00058807.1| COG2027: D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Thermobifida fusca]). InterPro: D-Ala-D-Ala carboxypeptidase 3 (S13) family pfam02113, Peptidase_S13,D-Ala-D-Ala carboxypeptidase 3 (S13) family. PBP4: D-alanyl-D-alanine carboxypeptid; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase 2332107 dacB 5175871 dacB Clavibacter michiganensis subsp. michiganensis NCPPB 382 D-alanyl-D-alanine carboxypeptidase YP_001222809.1 2330668 R 443906 CDS YP_001222810.1 148273249 5175007 complement(2332162..2332794) 1 NC_009480.1 DNA-invertase (Site-specific recombinase)(ZP_00016441.1| COG1961: Site-specific recombinases, DNA invertase Pin homologs [Rhodospirillum rubrum]; NP_061675.1| recombinase [Xylella fastidiosa]). InterPro: Site-specific recombinase pfam00239, Resolvase,Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface.; Specificity unclear; putative DNA-invertase/recombinase 2332794 5175007 CMM_2068 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-invertase/recombinase YP_001222810.1 2332162 R 443906 CDS YP_001222811.1 148273250 5175191 complement(2332896..2333174) 1 NC_009480.1 hypothetical protein (ZP_00227354.1| hypothetical protein Krad06001085 [Kineococcus radiotolerans SRS30216]; ZP_00050340.2| COG0532: Translation initiation factor 2 (IF-2; GTPase)[Magnetospirillum magnetotacticum]).; hypothetical protein 2333174 5175191 CMM_2069 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222811.1 2332896 R 443906 CDS YP_001222812.1 148273251 5174354 complement(2333276..2334481) 1 NC_009480.1 conserved membrane protein (ZP_00294063.1| COG2339: Predicted membrane protein [Thermobifida fusca]; NP_628289.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Function unclear; hypothetical protein 2334481 5174354 CMM_2070 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222812.1 2333276 R 443906 CDS YP_001222813.1 148273252 5175284 complement(2334589..2336016) 1 NC_009480.1 putative FAD/FMN-containing dehydrogenase/oxidoreductase (ZP_00227456.1| COG0277: FAD/FMN-containing dehydrogenases [Kineococcus radiotolerans SRS30216]; NP_826328.1| putative glycolate oxidase [Streptomyces avermitilis MA-4680]). InterPro: FAD linked oxidase C-terminal. pfam01565, FAD_binding_4, FAD binding domain. pfam02913, FAD-oxidase_C, FAD linked oxidases, C-terminal domain. glcD: glycolate oxidase subunit GlcD; Specificity unclear; putative FAD/FMN-containing dehydrogenase 2336016 5175284 CMM_2071 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative FAD/FMN-containing dehydrogenase YP_001222813.1 2334589 R 443906 CDS YP_001222814.1 148273253 5175177 2336075..2337010 1 NC_009480.1 putative DNA glycosylase (ZP_00139319.1| COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Pseudomonas aeruginosa UCBPP-PA14]; ZP_00277968.1| COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [Burkholderia fungorum LB400]). pfam06029,AlkA_N, AlkA N-terminal domain. pfam00730, HhH-GPD, HhH-GPD superfamily base excision DNA repair protein. This family contains a diverse range of structurally related DNA repair proteins.; Function unclear; putative DNA glycosylase 2337010 5175177 CMM_2072 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA glycosylase YP_001222814.1 2336075 D 443906 CDS YP_001222815.1 148273254 5175054 complement(2337014..2338063) 1 NC_009480.1 Region created by contig update; hypothetical protein 2338063 5175054 CMM_2073 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222815.1 2337014 R 443906 CDS YP_001222816.1 148273255 5175015 2338121..2340619 1 NC_009480.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity; ATP-dependent DNA ligase 2340619 5175015 CMM_2074 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent DNA ligase YP_001222816.1 2338121 D 443906 CDS YP_001222817.1 148273256 5174758 2340710..2341588 1 NC_009480.1 putative hydrolase (NP_437231.1| putative bifunctional enzyme 2-hydroxyhepta-2,4-diene-1,7-dioatesomerase 5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioatedecarboxylase protein [Sinorhizobium meliloti 1021]; NP_697278.1| fumarylacetoacetate hydrolase family protein [Brucella suis 1330]). InterPro: Fumarylacetoacetate (FAA) hydrolase family pfam01557,FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase family.; Function unclear; putative hydrolase 2341588 5174758 CMM_2075 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001222817.1 2340710 D 443906 CDS YP_001222818.1 148273257 5174782 2341631..2341768 1 NC_009480.1 hypothetical protein 2341768 5174782 CMM_2075A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222818.1 2341631 D 443906 CDS YP_001222819.1 148273258 5174831 2341812..2342720 1 NC_009480.1 hypothetical protein pfam01442, Apolipoprotein,Apolipoprotein A1/A4/E family.; hypothetical protein 2342720 5174831 CMM_2076 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222819.1 2341812 D 443906 CDS YP_001222820.1 148273259 5174732 complement(2342798..2344315) 1 NC_009480.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 2344315 aspA 5174732 aspA Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate ammonia-lyase YP_001222820.1 2342798 R 443906 CDS YP_001222821.1 148273260 5174637 2344422..2345273 1 NC_009480.1 conserved hypothetical protein (ZP_00326425.1| COG4328: Uncharacterized protein conserved in bacteria [Trichodesmium erythraeum IMS101]; NP_485314.1| hypothetical protein [Nostoc sp. PCC 7120]).; hypothetical protein 2345273 5174637 CMM_2078 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222821.1 2344422 D 443906 CDS YP_001222822.1 148273261 5175342 complement(2345295..2346041) 1 NC_009480.1 putative glycosyl transferase (NP_968447.1| putative glycosyl transferase [Bdellovibrio bacteriovorus HD100]; ZP_00188968.2| COG0463: Glycosyltransferases involved in cell wall biogenesis [Kineococcus radiotolerans SRS30216]; NP_738216.1| putative prenol monophospho-mannose synthase [Corynebacterium efficiens YS-314]). InterPro: Glycosyl transferase family 2 pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; glycosyl transferase family protein 2346041 5175342 CMM_2079 Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycosyl transferase family protein YP_001222822.1 2345295 R 443906 CDS YP_001222823.1 148273262 5173407 2346231..2346752 1 NC_009480.1 putative membrane protein (ZP_00121383.2| COG2246: Predicted membrane protein [Bifidobacterium longum DJO10A]; NP_627281.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Hypothetical protein; hypothetical protein 2346752 5173407 CMM_2080 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222823.1 2346231 D 443906 CDS YP_001222824.1 148273263 5174848 complement(2346772..2348049) 1 NC_009480.1 putative manganese transport protein, NRAMP family (NP_629145.1| putative metal ion transport protein [Streptomyces coelicolor A3(2)]; ZP_00188446.1| COG1914: Mn2+ and Fe2+ transporters of the NRAMP family [Rubrobacter xylanophilus DSM 9941]). pfam01566, Nramp,Natural resistance-associated macrophage protein. This family of membrane proteins are divalent cation transporters.; Specificity unclear; Mn2+/Fe2+ transporter 2348049 5174848 CMM_2081 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Mn2+/Fe2+ transporter YP_001222824.1 2346772 R 443906 CDS YP_001222825.1 148273264 5175926 complement(2348147..2349622) 1 NC_009480.1 putative xanthine/uracil permease, MFS superfamily (CAF19530.1| Xanthine/uracil permeases family [Corynebacterium glutamicum ATCC 13032]; NP_827562.1| putative hypoxanthine/guanine permease [Streptomyces avermitilis MA-4680]). , InterPro: Xanthine/uracil permeases family , pfam00860, Xan_ur_permease, Permease family. This family includes permeases for diverse substrates such as xanthine, uracil and vitamin C. However many members of this family are functionally uncharacterised and may transport other substrates.; Specificity unclear; MFS family xanthine/uracil permease 2349622 5175926 CMM_2082 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MFS family xanthine/uracil permease YP_001222825.1 2348147 R 443906 CDS YP_001222826.1 148273265 5174807 complement(2349748..2349999) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2349999 5174807 CMM_2083 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222826.1 2349748 R 443906 CDS YP_001222827.1 148273266 5173956 complement(2349996..2351177) 1 NC_009480.1 putative low-affinity inorganic phosphate permease (NP_599707.1| phosphate/sulphate permease [Corynebacterium glutamicum ATCC 13032]; NP_827595.1| putative transporter [Streptomyces avermitilis MA-4680]). InterPro: Phosphate transporter family pfam01384, PHO4, Phosphate transporter family.; Specificity unclear; low-affinity inorganic phosphate permease 2351177 pitB 5173956 pitB Clavibacter michiganensis subsp. michiganensis NCPPB 382 low-affinity inorganic phosphate permease YP_001222827.1 2349996 R 443906 CDS YP_001222828.1 148273267 5173533 complement(2351296..2352957) 1 NC_009480.1 putative carboxylesterase type B (NP_949230.1| putative carboxylesterase [Rhodopseudomonas palustris CGA009]; CAA17259.1| Probable carboxylesterase LipT [Mycobacterium tuberculosis H37Rv]). InterPro: Carboxylesterases type-B pfam00135, COesterase,Carboxylesterase.; High confidence in function and specificity; carboxylesterase 2352957 lipT 5173533 lipT Clavibacter michiganensis subsp. michiganensis NCPPB 382 carboxylesterase YP_001222828.1 2351296 R 443906 CDS YP_001222829.1 148273268 5174065 complement(2352954..2354537) 1 NC_009480.1 conserved hypothetical protein (NP_336756.1| conserved hypothetical protein [Mycobacterium tuberculosis CDC1551]; NP_940012.1| Conserved hypothetical protein [Corynebacterium diphtheriae]). pfam01928, CYTH, CYTH domain. pfam05235, CHAD, CHAD domain. The CHAD domain is an alpha-helical domain functionally associated with the pfam01928 domains. It has conserved histidines that may chelate metals.; hypothetical protein 2354537 5174065 CMM_2086 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222829.1 2352954 R 443906 CDS YP_001222830.1 148273269 5174710 2354629..2355816 1 NC_009480.1 conserved hypothetical protein (|ZP_00059173.1| COG1295: Predicted membrane protein [Thermobifida fusca]; NP_737633.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam03631,Ribonuclease_BN, Ribonuclease BN-like family. This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity.; Family membership; hypothetical protein 2355816 5174710 CMM_2087 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222830.1 2354629 D 443906 CDS YP_001222831.1 148273270 5174659 complement(2355761..2356780) 1 NC_009480.1 putative NADP-dependent oxidoreductase (ZP_00226498.1| COG2130: Putative NADP-dependent oxidoreductases [Kineococcus radiotolerans SRS30216]; NP_826953.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative oxidoreductase 2356780 5174659 CMM_2088 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001222831.1 2355761 R 443906 CDS YP_001222832.1 148273271 5174427 complement(2356917..2357858) 1 NC_009480.1 putative NAD-dependent epimerase/dehydratase (ZP_00228901.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]; AAO42400.1| putative pinoresinol- lariciresinol reductase [Arabidopsis thaliana]). InterPro: Isoflavone reductase; Family membership; putative NAD-dependent epimerase/dehydratase 2357858 5174427 CMM_2089 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD-dependent epimerase/dehydratase YP_001222832.1 2356917 R 443906 CDS YP_001222833.1 148273272 5174462 complement(2359330..2360022) 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_294134.1| oxidoreductase, short-chain dehydrogenase/reductase family [Deinococcus radiodurans]; NP_738947.1| putative reductase [Corynebacterium efficiens YS-314]). InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 2360022 5174462 CMM_2090 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001222833.1 2359330 R 443906 CDS YP_001222834.1 148273273 5174399 2360157..2360507 1 NC_009480.1 hypothetical protein 2360507 5174399 CMM_2091 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222834.1 2360157 D 443906 CDS YP_001222835.1 148273274 5174263 2360643..2361101 1 NC_009480.1 chaperone, heat shock protein, HSP20 family (CAD59401.1| putative heat shock protein 20_1 [Propionibacterium freudenreichii subsp. shermanii]; NP_821867.1| putative heat shock protein [Streptomyces avermitilis MA-4680]). InterPro: Heat shock hsp20 (alpha crystallin) proteins family pfam00011, HSP20, Hsp20/alpha crystallin family.; High confidence in function and specificity; HSP20 family protein 2361101 hsp20 5174263 hsp20 Clavibacter michiganensis subsp. michiganensis NCPPB 382 HSP20 family protein YP_001222835.1 2360643 D 443906 CDS YP_001222836.1 148273275 5175635 complement(2361212..2363728) 1 NC_009480.1 putative siderophore biosynthesis protein (NP_931792.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00162775.2| COG4264: Siderophore synthetase component [Anabaena variabilis ATCC 29413]). two-domain protein: N-terminal: putative acetyl transferase (NC_003155.2, AlcB,Streptomyces avermitilis MA-4680, putative aceytltranferase). C-terminal: NC_003155.2, Streptomyces avermitilis MA-4680, putative siderophore biosynthetic enzyme, AlcC. pfam04183, IucA_IucC, IucA / IucC family. IucA and IucC catalyse discrete steps in biosynthesis of the siderophore aerobactin from N epsilon-acetyl-N epsilon-hydroxylysine and citrate.; Function unclear; putative siderophore biosynthesis protein 2363728 alcBC 5175635 alcBC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative siderophore biosynthesis protein YP_001222836.1 2361212 R 443906 CDS YP_001222837.1 148273276 5173106 complement(2363725..2365095) 1 NC_009480.1 putative monooxygenase/hydroxylase (NP_826448.1| putative monooxigenase, AlcA, Streptomyces avermitilis MA-4680; NP_405116.1| putative siderophore biosynthetic enzyme, Yersinia pestis; ZP_00119405.1| COG3486: Lysine/ornithine N-monooxygenase, Cytophaga hutchinsonii); Specificity unclear; putative siderophore biosynthesis enzyme/monooxygenase 2365095 alcA 5173106 alcA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative siderophore biosynthesis enzyme/monooxygenase YP_001222837.1 2363725 R 443906 CDS YP_001222838.1 148273277 5173530 complement(2365092..2366702) 1 NC_009480.1 putative L-2,4-diaminobutyrate decarboxylase (NP_826449.1| putative L-2,4-diaminobutyrate decarboxylase [Streptomyces avermitilis MA-4680]; NP_405115.1| putative decarboxylase [Yersinia pestis]). InterPro: Pyridoxal-dependent decarboxylase family pfam00282, Pyridoxal_deC,Pyridoxal-dependent decarboxylase conserved domain.; Specificity unclear; L-amino acid decarboxylase 2366702 5173530 CMM_2095 Clavibacter michiganensis subsp. michiganensis NCPPB 382 L-amino acid decarboxylase YP_001222838.1 2365092 R 443906 CDS YP_001222839.1 148273278 5174298 2366913..2367224 1 NC_009480.1 hypothetical protein 2367224 5174298 CMM_2095A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222839.1 2366913 D 443906 CDS YP_001222840.1 148273279 5174338 2367226..2367378 1 NC_009480.1 hypothetical protein 2367378 5174338 CMM_2095B Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222840.1 2367226 D 443906 CDS YP_001222841.1 148273280 5174195 2367480..2367764 1 NC_009480.1 hypothetical protein 2367764 5174195 CMM_2096 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222841.1 2367480 D 443906 CDS YP_001222842.1 148273281 5174114 2367761..2368054 1 NC_009480.1 hypothetical protein 2368054 5174114 CMM_2097 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222842.1 2367761 D 443906 CDS YP_001222843.1 148273282 5173958 2368102..2368998 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_737722.1| putative oxidoreductase [Corynebacterium efficiens YS-314]; NP_641514.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306])). pfam00106,adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 2368998 5173958 CMM_2098 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001222843.1 2368102 D 443906 CDS YP_001222844.1 148273283 5173966 2369127..2369858 1 NC_009480.1 hypothetical protein (ZP_00226806.1| hypothetical protein Krad06002561 [Kineococcus radiotolerans SRS30216]; NP_962000.1| hypothetical protein MAP3066c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 2369858 5173966 CMM_2099 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222844.1 2369127 D 443906 CDS YP_001222845.1 148273284 5173996 complement(2370010..2370741) 1 NC_009480.1 putative membrane protein; hypothetical protein 2370741 5173996 CMM_2100 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222845.1 2370010 R 443906 CDS YP_001222846.1 148273285 5173847 complement(2371085..2371822) 1 NC_009480.1 hypothetical protein 2371822 5173847 CMM_2101 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222846.1 2371085 R 443906 CDS YP_001222847.1 148273286 5173761 2372140..2373021 1 NC_009480.1 putative membrane protein containing a 2Fe-2S domain (ZP_00293646.1| COG4244: Predicted membrane protein [Thermobifida fusca]; ZP_00227494.1| COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases [Kineococcus radiotolerans SRS30216]). N:terminal: COG4244, COG4244, Predicted membrane protein C-terminal: InterPro: Rieske iron-sulfur protein 2Fe-2S subunit pfam00355, Rieske, Rieske [2Fe-2S] domain. COG2146, {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases; Function unclear; 2Fe-2S domain-containing protein 2373021 5173761 CMM_2102 Clavibacter michiganensis subsp. michiganensis NCPPB 382 2Fe-2S domain-containing protein YP_001222847.1 2372140 D 443906 CDS YP_001222848.1 148273287 5173824 complement(2373103..2374563) 1 NC_009480.1 conserved hypothetical protein, putative protease (T35375 probable membrane protein - Streptomyces coelicolor; ZP_00228735.1| COG2268: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). N-terminal: pfam01145, Band_7, SPFH domain / Band 7 family. C-terminal: pfam03149, Flotillin, Flotillin family.; Function unclear; hypothetical protein 2374563 5173824 CMM_2103 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222848.1 2373103 R 443906 CDS YP_001222849.1 148273288 5173683 complement(2374595..2375083) 1 NC_009480.1 Function unclear; hypothetical protein 2375083 5173683 CMM_2104 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222849.1 2374595 R 443906 CDS YP_001222850.1 148273289 5173636 2375265..2375525 1 NC_009480.1 hypothetical protein (NP_822693.1| hypothetical protein SAV1518 [Streptomyces avermitilis MA-4680]).; hypothetical protein 2375525 5173636 CMM_2105 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222850.1 2375265 D 443906 CDS YP_001222851.1 148273290 5173697 2375647..2376999 1 NC_009480.1 putative sugar ABC transporter, binding protein (NP_624969.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00121005.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]). InterPro: Bacterial extracellular solute-binding protein family 1. pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, binding protein 2376999 5173697 CMM_2106 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, binding protein YP_001222851.1 2375647 D 443906 CDS YP_001222852.1 148273291 5173548 2376996..2378012 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00227865.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]; ZP_00121800.2| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 2378012 5173548 CMM_2107 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001222852.1 2376996 D 443906 CDS YP_001222853.1 148273292 5173519 2378009..2378977 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00121009.2| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]; NP_631458.1| putative binding-protein dependent transport protein. [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 2378977 5173519 CMM_2108 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001222853.1 2378009 D 443906 CDS YP_001222854.1 148273293 5173595 2379114..2382167 1 NC_009480.1 putative beta-galactosidase (Q59140|BGAL_ARTSB Beta-galactosidase (Lactase); NP_823271.1| putative beta-galactosidase [Streptomyces avermitilis MA-4680]). pfam02837, Glyco_hydro_2_N, Glycosyl hydrolases family 2,sugar binding domain. pfam02836, Glyco_hydro_2_C, Glycosyl hydrolases family 2, TIM barrel domain. pfam02929,Bgal_small_N, Beta galactosidase small chain, N terminal domain. pfam02930, Bgal_small_C, Beta galactosidase small chain, C terminal domain.; High confidence in function and specificity; beta-galactosidase 2382167 lacZ 5173595 lacZ Clavibacter michiganensis subsp. michiganensis NCPPB 382 beta-galactosidase YP_001222854.1 2379114 D 443906 CDS YP_001222855.1 148273294 5173676 2382278..2383564 1 NC_009480.1 putative sugar alcohol dehydrogenase (Q9ZBU1|XYOA_STRCO Probable xylitol oxidase; ZP_00228154.1| COG0277: FAD/FMN-containing dehydrogenases [Kineococcus radiotolerans SRS30216]). pfam01565,FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are; Specificity unclear; putative sugar alcohol dehydrogenase 2383564 5173676 CMM_2110 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar alcohol dehydrogenase YP_001222855.1 2382278 D 443906 CDS YP_001222856.1 148273295 5173483 2383679..2383948 1 NC_009480.1 putative glutaredoxin (ZP_00227600.1| COG0695: Glutaredoxin and related proteins [Kineococcus radiotolerans SRS30216]; NP_629335.1| putative glutaredoxin-like protein [Streptomyces coelicolor A3(2)]). InterPro: Thioredoxin. pfam00462, Glutaredoxin,Glutaredoxin. redox_disulf_1: redox-active disulfide; Function unclear; putative glutaredoxin 2383948 5173483 CMM_2111 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutaredoxin YP_001222856.1 2383679 D 443906 CDS YP_001222857.1 148273296 5173370 2383952..2385421 1 NC_009480.1 conserved hypothetical protein, putative phosphotransferase (ZP_00228505.1| COG3281: Uncharacterized protein, probably involved in trehalose biosynthesis [Kineococcus radiotolerans SRS30216]; ZP_00293344.1| COG3281: Uncharacterized protein, probably involved in trehalose biosynthesis [Thermobifida fusca]).; Function unclear; putative phosphotransferase 2385421 5173370 CMM_2112 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphotransferase YP_001222857.1 2383952 D 443906 CDS YP_001222858.1 148273297 5173630 2385893..2386117 1 NC_009480.1 Hypothetical protein; hypothetical protein 2386117 5173630 CMM_2113 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222858.1 2385893 D 443906 CDS YP_001222859.1 148273298 5174042 2386220..2388385 1 NC_009480.1 putative protease II (Oligopeptidase B)(NP_335233.1| protease II [Mycobacterium tuberculosis CDC1551]; NP_940260.1| Putative prolyl oligopeptidase [Corynebacterium diphtheriae NCTC 13129]). pfam02897,Peptidase_S9_N, Prolyl oligopeptidase, N-terminal beta-propeller domain. pfam00326, Peptidase_S9, Prolyl oligopeptidase family. InterPro: Prolyl oligopeptidase N-terminal beta-propeller domain.; High confidence in function and specificity; putative protease II (oligopeptidase B) 2388385 ptrB 5174042 ptrB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protease II (oligopeptidase B) YP_001222859.1 2386220 D 443906 CDS YP_001222860.1 148273299 5173647 2388531..2389358 1 NC_009480.1 hydroxyethylthiazole kinase (NP_713545.1| hydroxyethylthiazole kinase [Leptospira interrogans serovar lai str. 56601]; Q8X7G3|THIM_ECO57 Hydroxyethylthiazole kinase (4-methyl-5-beta-hydroxyethylthiazole kinase) (Thz kinase) (TH kinase)). pfam02110, HK, Hydroxyethylthiazole kinase family.; High confidence in function and specificity; hypothetical protein 2389358 thiM 5173647 thiM Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222860.1 2388531 D 443906 CDS YP_001222861.1 148273300 5175026 2389355..2391586 1 NC_009480.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; multifunctional thiamine-phosphate pyrophosphorylase/synthase/phosphomethylpyrimidine kinase 2391586 thiED 5175026 thiED Clavibacter michiganensis subsp. michiganensis NCPPB 382 multifunctional thiamine-phosphate pyrophosphorylase/synthase/phosphomethylpyrimidine kinase YP_001222861.1 2389355 D 443906 CDS YP_001222862.1 148273301 5175615 2391766..2392656 1 NC_009480.1 conserved hypothetical protein, putative fusion protein. N-terminal: COG1917, COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain (NP_534846.1| conserved hypothetical protein [Agrobacterium tumefaciens str. C58]; ZP_00105951.1| COG1917: Uncharacterized conserved protein, contains double-stranded beta-helix domain [Nostoc punctiforme]). C-terminal: similarity to NP_641577.1| hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]; ZP_00205709.1| hypothetical protein Psyr022367 [Pseudomonas syringae pv. syringae B728a]). panD: aspartate 1-decarboxylase; Function unclear; putative fusion protein 2392656 5175615 CMM_2117 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative fusion protein YP_001222862.1 2391766 D 443906 CDS YP_001222863.1 148273302 5173555 2392771..2394168 1 NC_009480.1 putative sugar MFS permease (BAC00372.1| Permeases of the major facilitator superfamily [Corynebacterium glutamicum ATCC 13032]; ZP_00227700.1| COG0477: Permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam00083, Sugar_tr, Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative sugar MFS permease 2394168 5173555 CMM_2118 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar MFS permease YP_001222863.1 2392771 D 443906 CDS YP_001222864.1 148273303 5175894 2394451..2394660 1 NC_009480.1 Hypothetical protein; hypothetical protein 2394660 5175894 CMM_2119 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222864.1 2394451 D 443906 CDS YP_001222865.1 148273304 5173275 complement(2394728..2396863) 1 NC_009480.1 putative DNA helicase (NP_787246.1| DNA helicase [Tropheryma whipplei str. Twist]). pfam00176, SNF2_N, SNF2 family N-terminal domain. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative DNA helicase 2396863 5173275 CMM_2120 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA helicase YP_001222865.1 2394728 R 443906 CDS YP_001222866.1 148273305 5173426 2397158..2398306 1 NC_009480.1 putative glutathion S-transferase (ZP_00190023.2| COG0435: Predicted glutathione S-transferase [Kineococcus radiotolerans SRS30216]; NP_600487.1| predicted glutathione S-transferase [Corynebacterium glutamicum ATCC 13032]).; Family membership; putative glutathione S-transferase 2398306 5173426 CMM_2121 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glutathione S-transferase YP_001222866.1 2397158 D 443906 CDS YP_001222867.1 148273306 5173249 2398306..2399100 1 NC_009480.1 putative esterase (BAA82510.1| esterase HDE [petroleum-degrading bacterium HD-1]; ZP_00312658.1| COG0657: Esterase/lipase [Clostridium thermocellum ATCC 27405]).; Family membership; putative esterase 2399100 5173249 CMM_2122 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001222867.1 2398306 D 443906 CDS YP_001222868.1 148273307 5172974 complement(2399063..2399437) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2399437 5172974 CMM_2123 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222868.1 2399063 R 443906 CDS YP_001222869.1 148273308 5173354 2399572..2400084 1 NC_009480.1 conserved hypothetical protein (NP_241345.1| BH0479 unknown conserved protein in others [Bacillus halodurans C-125]; NP_993986.1| TPR-repeat-containing proteins [Yersinia pestis biovar Medievalis str. 91001]). weak similarity to: cd00189, TPR, Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi,plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; Function unclear; hypothetical protein 2400084 5173354 CMM_2124 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222869.1 2399572 D 443906 CDS YP_001222870.1 148273309 5174452 2400081..2400482 1 NC_009480.1 hypothetical protein 2400482 5174452 CMM_2125 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222870.1 2400081 D 443906 CDS YP_001222871.1 148273310 5173224 2400540..2401580 1 NC_009480.1 putative Zn-dependant alcohol dehydrogenase (NP_102793.1| alcohol dehydrogenase [Mesorhizobium loti MAFF303099]; NP_532825.1| alcohol dehydrogenase [Agrobacterium tumefaciens str. C58]). pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependant alcohol dehydrogenase 2401580 5173224 CMM_2126 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant alcohol dehydrogenase YP_001222871.1 2400540 D 443906 CDS YP_001222872.1 148273311 5173125 complement(2401596..2401913) 1 NC_009480.1 conserved hypothetical protein (CAA15545.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_925803.1| hypothetical protein gsl2857 [Gloeobacter violaceus PCC 7421]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase.; Function unclear; hypothetical protein 2401913 5173125 CMM_2127 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222872.1 2401596 R 443906 CDS YP_001222873.1 148273312 5174009 complement(2401961..2403715) 1 NC_009480.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 2403715 poxB 5174009 poxB Clavibacter michiganensis subsp. michiganensis NCPPB 382 pyruvate dehydrogenase YP_001222873.1 2401961 R 443906 CDS YP_001222874.1 148273313 5173908 2403823..2404554 1 NC_009480.1 conserved hypothetical protein (NP_626020.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_602236.1| hypothetical protein NCgl2940 [Corynebacterium glutamicum ATCC13032]).; Function unclear; hypothetical protein 2404554 5173908 CMM_2129 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222874.1 2403823 D 443906 CDS YP_001222875.1 148273314 5174884 complement(2404551..2405513) 1 NC_009480.1 putative Zn-dependant oxidoreductase (NP_733654.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; NP_962452.1| hypothetical protein MAP3518c [Mycobacterium avium subsp. paratuberculosis str. k10]). InterPro: Zinc-containing alcohol dehydrogenase superfamily pfam00107,ADH_zinc_N, Zinc-binding dehydrogenase.; Specificity unclear; putative Zn-dependant oxidoreductase 2405513 5174884 CMM_2130 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant oxidoreductase YP_001222875.1 2404551 R 443906 CDS YP_001222876.1 148273315 5174521 2405657..2406577 1 NC_009480.1 putative transcriptional regulator, LysR family (ZP_00267509.1| COG0583: Transcriptional regulator [Rhodospirillum rubrum]; NP_102796.1| probable transcriptional regulator [Mesorhizobium loti MAFF303099]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466,LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 2406577 5174521 CMM_2131 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001222876.1 2405657 D 443906 CDS YP_001222877.1 148273316 5173459 2408857..2409756 1 NC_009480.1 putative transcriptional regulator, TetR family (P09164|TER4_ECOLI Tetracycline repressor protein class D; NP_792454.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]).; Specificity unclear; TetR family transcriptional regulator 2409756 5173459 CMM_2132 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001222877.1 2408857 D 443906 CDS YP_001222878.1 148273317 5173024 complement(2409753..2410391) 1 NC_009480.1 putative lipase/esterase (ZP_00110422.1| COG2755: Lysophospholipase L1 and related esterases [Nostoc punctiforme]; NP_641188.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri str. 306]). pfam00657,Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; putative lipase/esterase 2410391 5173024 CMM_2133 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative lipase/esterase YP_001222878.1 2409753 R 443906 CDS YP_001222879.1 148273318 5173156 complement(2410435..2410884) 1 NC_009480.1 putative membrane protein; hypothetical protein 2410884 5173156 CMM_2134 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222879.1 2410435 R 443906 CDS YP_001222880.1 148273319 5175490 complement(2410881..2412407) 1 NC_009480.1 putative nucleoside-diphosphate-sugar epimerase (NP_822386.1| hypothetical protein [Streptomyces avermitilis MA-4680]; ZP_00227908.1| COG0702: Predicted nucleoside-diphosphate-sugar epimerases [Kineococcus radiotolerans SRS30216]).; Function unclear; hypothetical protein 2412407 5175490 CMM_2135 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222880.1 2410881 R 443906 CDS YP_001222881.1 148273320 5175625 complement(2412481..2413242) 1 NC_009480.1 hypothetical protein (ZP_00198157.1| COG3832: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2413242 5175625 CMM_2136 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222881.1 2412481 R 443906 CDS YP_001222882.1 148273321 5173482 2413422..2414360 1 NC_009480.1 putative sugarkinase (Glucose kinase) (CAB07107.1| POSSIBLE SUGAR KINASE [Mycobacterium tuberculosis H37Rv]; NP_822651.1| putative sugar kinase [Streptomyces avermitilis MA-4680]). pfam00480, ROK, ROK family.; Specificity unclear; putative sugarkinase 2414360 5173482 CMM_2137 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugarkinase YP_001222882.1 2413422 D 443906 CDS YP_001222883.1 148273322 5174885 complement(2414413..2416014) 1 NC_009480.1 conserved hypothetical protein (NP_630250.1| hypothetical protein SC1A9.09 [Streptomyces coelicolor A3(2)]; ZP_00198190.1| COG1387: Histidinol phosphatase and related hydrolases of the PHP family [Kineococcus radiotolerans SRS30216]). pfam02231, PHP_N, PHP domain N-terminal region. The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. weak similarity to: COG1387, HIS2, Histidinol phosphatase and related hydrolases of the PHP family.; hypothetical protein 2416014 5174885 CMM_2138 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222883.1 2414413 R 443906 CDS YP_001222884.1 148273323 5174067 complement(2416143..2417408) 1 NC_009480.1 putative cyanate MFS permease (ZP_00225824.1| COG2807: Cyanate permease [Kineococcus radiotolerans SRS30216]; NP_642656.1| MFS transporter [Xanthomonas axonopodis pv. citri str. 306]). TIGRFAM (TIGR00896): Cyanate transport system protein CynX; Specificity unclear; MFS family permease 2417408 cynX 5174067 cynX Clavibacter michiganensis subsp. michiganensis NCPPB 382 MFS family permease YP_001222884.1 2416143 R 443906 CDS YP_001222885.1 148273324 5174640 2417443..2418129 1 NC_009480.1 conserved hypothetical protein (ZP_00199464.2| hypothetical protein Krad06000208 [Kineococcus radiotolerans SRS30216]; NP_216552.1| hypothetical protein Rv2036 [Mycobacterium tuberculosis H37Rv]).; hypothetical protein 2418129 5174640 CMM_2140 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222885.1 2417443 D 443906 CDS YP_001222886.1 148273325 5173159 complement(2418126..2419058) 1 NC_009480.1 multifunctional Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase (EC 2.7.1.26) (Flavokinase); FMN adenylyltransferase (EC 2.7.7.2) (FAD pyrophosphorylase) (FAD synthetase)] (NP_823722.1| putative riboflavin kinase [Streptomyces avermitilis MA-4680]; NP_738481.1| riboflavin kinase/FMN adenylyltransferase [Corynebacterium efficiens YS-314]). pfam06574, Flavokinase, Riboflavin kinase (Flavokinase). pfam01687, FAD_Synth, Riboflavin kinase / FAD synthetase. InterPro: Riboflavin kinase / FAD synthetase ribF: riboflavin biosynthesis protein R.; High confidence in function and specificity; bifunctional riboflavin kinase/FMN adenylyltransferase 2419058 ribF 5173159 ribF Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional riboflavin kinase/FMN adenylyltransferase YP_001222886.1 2418126 R 443906 CDS YP_001222887.1 148273326 5175877 complement(2419061..2419522) 1 NC_009480.1 putative membrane protein (NP_827963.1| putative integral membrane protein [Streptomyces avermitilis MA-4680]; ZP_00227300.1| hypothetical protein Krad06001357 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2419522 5175877 CMM_2142 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222887.1 2419061 R 443906 CDS YP_001222888.1 148273327 5173424 complement(2419560..2419928) 1 NC_009480.1 putative membrane protein (NP_789537.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_625839.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 2419928 5173424 CMM_2143 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222888.1 2419560 R 443906 CDS YP_001222889.1 148273328 5173532 complement(2419925..2420884) 1 NC_009480.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2420884 truB 5173532 truB Clavibacter michiganensis subsp. michiganensis NCPPB 382 tRNA pseudouridine synthase B YP_001222889.1 2419925 R 443906 CDS YP_001222890.1 148273329 5174920 2420971..2421966 1 NC_009480.1 Putative 2-dehydropantoate 2-reductase (NP_624781.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; NP_949896.1| putative 2-dehydropantoate 2-reductase [Rhodopseudomonas palustris CGA009]). Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity). pfam02558,ApbA, Ketopantoate reductase PanE/ApbA. InterPro: Ketopantoate reductase ApbA/PanE apbA_panE: 2-dehydropantoate 2-reductase; High confidence in function and specificity; 2-dehydropantoate 2-reductase 2421966 apbA 5174920 apbA Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-dehydropantoate 2-reductase YP_001222890.1 2420971 D 443906 CDS YP_001222891.1 148273330 5175018 complement(2422016..2422582) 1 NC_009480.1 hypothetical protein 2422582 5175018 CMM_2146 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222891.1 2422016 R 443906 CDS YP_001222892.1 148273331 5172937 2422621..2423499 1 NC_009480.1 A/G-specific adenine glycosylase (NP_825884.1| putative adenine glycosylase [Streptomyces avermitilis MA-4680]; ZP_00293144.1| COG1194: A/G-specific DNA glycosylase [Thermobifida fusca]). ADENINE GLYCOSYLASE ACTIVE ON G-A MISPAIRS. MUTY ALSO CORRECTS ERROR-PRONE DNA SYNTHESIS PAST GO LESIONS WHICH ARE DUE TO THE OXIDATIVELY DAMAGED FORM OF GUANINE: 78-DIHYDRO-8- OXOGUANINE.; High confidence in function and specificity; A/G-specific adenine glycosylase 2423499 mutY 5172937 mutY Clavibacter michiganensis subsp. michiganensis NCPPB 382 A/G-specific adenine glycosylase YP_001222892.1 2422621 D 443906 CDS YP_001222893.1 148273332 5174074 complement(2423544..2424044) 1 NC_009480.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2424044 rbfA 5174074 rbfA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribosome-binding factor A YP_001222893.1 2423544 R 443906 CDS YP_001222894.1 148273333 5174013 complement(2424224..2427058) 1 NC_009480.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2427058 infB 5174013 infB Clavibacter michiganensis subsp. michiganensis NCPPB 382 translation initiation factor IF-2 YP_001222894.1 2424224 R 443906 CDS YP_001222895.1 148273334 5175947 complement(2427155..2427448) 1 NC_009480.1 Region created by contig update; putative nucleic-acid-binding protein 2427448 5175947 CMM_2150 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleic-acid-binding protein YP_001222895.1 2427155 R 443906 CDS YP_001222896.1 148273335 5174208 complement(2427499..2428506) 1 NC_009480.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2428506 nusA 5174208 nusA Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcription elongation factor NusA YP_001222896.1 2427499 R 443906 CDS YP_001222897.1 148273336 5174586 complement(2428593..2430365) 1 NC_009480.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 2430365 proS 5174586 proS Clavibacter michiganensis subsp. michiganensis NCPPB 382 prolyl-tRNA synthetase YP_001222897.1 2428593 R 443906 CDS YP_001222898.1 148273337 5175736 complement(2430397..2431398) 1 NC_009480.1 putative NAD(P)H dependant steroid dehydrogenase/isomerase (AAL01055.1| putative steroid dehydrogenase [Photobacterium profundum]; NP_717355.1| 3-beta hydroxysteroid dehydrogenase/isomerase family protein [Shewanella oneidensis MR-1]). pfam01073, 3Beta_HSD, 3-beta hydroxysteroid dehydrogenase/isomerase family.; Specificity unclear; putative NAD(P)H steroid dehydrogenase/isomerase 2431398 5175736 CMM_2153 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD(P)H steroid dehydrogenase/isomerase YP_001222898.1 2430397 R 443906 CDS YP_001222899.1 148273338 5175223 complement(2431395..2434067) 1 NC_009480.1 putative acyl-CoA synthetase (ZP_00353402.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Kineococcus radiotolerans SRS30216]; two-domain protein: N-terminal (AA 1-330):COG0596, MhpC,Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); pfam00561, Abhydrolase_1,alpha/beta hydrolase fold (NP_717353.1| hydrolase,alpha/beta hydrolase fold family [Shewanella oneidensis MR-1]). C-terminal (330- ):COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; pfam00501,AMP-binding, AMP-binding enzyme (ZP_00039494.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Xylella fastidiosa Dixon]). InterPro: AMP-dependent synthetase and ligase.; Function unclear; putative acyl-CoA synthetase 2434067 5175223 CMM_2154 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyl-CoA synthetase YP_001222899.1 2431395 R 443906 CDS YP_001222900.1 148273339 5173048 complement(2434075..2435106) 1 NC_009480.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 2435106 5173048 CMM_2155 Clavibacter michiganensis subsp. michiganensis NCPPB 382 3-oxoacyl-(acyl carrier protein) synthase III YP_001222900.1 2434075 R 443906 CDS YP_001222901.1 148273340 5173097 complement(2435214..2436359) 1 NC_009480.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2436359 ispG 5173097 ispG Clavibacter michiganensis subsp. michiganensis NCPPB 382 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_001222901.1 2435214 R 443906 CDS YP_001222902.1 148273341 5175767 complement(2436450..2437868) 1 NC_009480.1 putative membrane-associated zinc metalloprotease,family M50 (YP_062170.1| zinc metalloprotease [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059010.1| COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Thermobifida fusca]; NP_823738.1| hypothetical protein [Streptomyces avermitilis MA-4680]). InterPro: PDZ domain (also known as DHR or GLGF) TIGR00054: membrane-associated zinc met; Specificity unclear; M50 family zinc metalloprotease 2437868 5175767 CMM_2157 Clavibacter michiganensis subsp. michiganensis NCPPB 382 M50 family zinc metalloprotease YP_001222902.1 2436450 R 443906 CDS YP_001222903.1 148273342 5173501 2438004..2439254 1 NC_009480.1 putative serine/threonine-protein kinase (NP_623114.1| Serine/threonine protein kinase [Thermoanaerobacter tengcongensis]; NP_785211.1| serine/threonine protein kinase (putative) [Lactobacillus plantarum WCFS1]). pfam00069, Pkinase, Protein kinase domain. InterPro: Serine/Threonine protein kinase.; Function unclear; putative serine/threonine protein kinase 2439254 pknF 5173501 pknF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine/threonine protein kinase YP_001222903.1 2438004 D 443906 CDS YP_001222904.1 148273343 5173421 2439251..2439862 1 NC_009480.1 hypothetical protein 2439862 5173421 CMM_2159 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222904.1 2439251 D 443906 CDS YP_001222905.1 148273344 5174690 complement(2439980..2441062) 1 NC_009480.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2441062 dxrA 5174690 dxrA Clavibacter michiganensis subsp. michiganensis NCPPB 382 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_001222905.1 2439980 R 443906 CDS YP_001222906.1 148273345 5175876 complement(2441071..2442093) 1 NC_009480.1 putative peptidyl-prolyl cis-trans isomerase (YP_062168.1| peptidylprolyl isomerase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056093.1| putative peptidyl-prolyl cis-trans isomerase [Propionibacterium acnes KPA171202]). pfam00254, FKBP_C, FKBP-type peptidyl-prolyl cis-trans isomerase (twice). InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase).; Family membership; putative peptidylprolyl isomerase 2442093 5175876 CMM_2161 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptidylprolyl isomerase YP_001222906.1 2441071 R 443906 CDS YP_001222907.1 148273346 5173613 complement(2442228..2442713) 1 NC_009480.1 conserved hypothetical protein (YP_062164.1| Hypothetical protein Lxx12120 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00310296.1| COG1764: Predicted redox protein, regulator of disulfide bond formation [Cytophaga hutchinsonii]). pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.; Function unclear; hypothetical protein 2442713 5173613 CMM_2162 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222907.1 2442228 R 443906 CDS YP_001222908.1 148273347 5173550 2442785..2444200 1 NC_009480.1 putative 4-aminobutyrate aminotransferase (Gamma-amino-N-butyrate transaminase) (YP_062163.1| 4-aminobutyrate aminotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; P40829|GABT_MYCLE 4-aminobutyrate aminotransferase ((S)-3-amino-2-methylpropionate transaminase) (Gamma-amino-N-butyrate transaminase)). InterPro: 4-aminobutyrate aminotransferase bacterial.; High confidence in function and specificity; putative 4-aminobutyrate aminotransferase 2444200 gabT 5173550 gabT Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 4-aminobutyrate aminotransferase YP_001222908.1 2442785 D 443906 CDS YP_001222909.1 148273348 5174583 2444200..2445210 1 NC_009480.1 putative asparaginase II (YP_062162.1| Hypothetical protein Lxx12130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628361.1| hypothetical protein SCO4185 [Streptomyces coelicolor A3(2)]; ZP_00192634.1| COG4448: L-asparaginase II [Mesorhizobium sp. BNC1]). pfam06089,Asparaginase_II, L-asparaginase II.; Specificity unclear; putative asparaginase II 2445210 5174583 CMM_2164 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative asparaginase II YP_001222909.1 2444200 D 443906 CDS YP_001222910.1 148273349 5173285 complement(2445200..2448691) 1 NC_009480.1 conserved hypothetical protein with duplicated ATPase domain (CAB77299.1| putative cell division-related protein [Streptomyces coelicolor A3(2)]; NP_737190.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01580, FtsK_SpoIIIE, FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE, which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.; Family membership; hypothetical protein 2448691 5173285 CMM_2165 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222910.1 2445200 R 443906 CDS YP_001222911.1 148273350 5173136 complement(2448782..2451325) 1 NC_009480.1 conserved membrane protein containing transglutaminase domain, putative cysteine protease (YP_062159.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00120584.1| COG1305: Transglutaminase-like enzymes, putative cysteine proteases [Bifidobacterium longum DJO10A]). pfam01027, UPF0005,Uncharacterised protein family UPF0005. pfam01841,Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function.; Function unclear; hypothetical protein 2451325 5173136 CMM_2166 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222911.1 2448782 R 443906 CDS YP_001222912.1 148273351 5173931 complement(2451322..2452782) 1 NC_009480.1 conserved hypothetical protein (YP_062158.1| conserved hypothetical protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696370.1| narrowly conserved hypothetical protein with duf54 [Bifidobacterium longum NCC2705]). pfam01882, DUF58, Protein of unknown function DUF58. This family of prokaryotic proteins have no known function. InterPro: Protein of unknown function DUF58.; Function unclear; hypothetical protein 2452782 5173931 CMM_2167 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222912.1 2451322 R 443906 CDS YP_001222913.1 148273352 5172921 complement(2452779..2453822) 1 NC_009480.1 MoxR-like ATPase, putative regulator (YP_062157.1| methanol dehydrogenase regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_622051.1| MoxR-like ATPases [Thermoanaerobacter tengcongensis]). pfam00004, AAA,ATPase family associated with various cellular activities (AAA). AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.; Function unclear; MoxR-like ATPase, putative regulator 2453822 5172921 CMM_2168 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MoxR-like ATPase, putative regulator YP_001222913.1 2452779 R 443906 CDS YP_001222914.1 148273353 5174021 complement(2453881..2459895) 1 NC_009480.1 putative RTX toxin (YP_062156.1| fibronectin-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00206687.1| COG5295: Autotransporter adhesin [Bifidobacterium longum DJO10A]; NP_696368.1| large protein with C-terminal fibronectin type III domain [Bifidobacterium longum NCC2705]). pfam00041, fn3,Fibronectin type III domain (twice). InterPro: Fibronectin type III domain.; Function unclear; putative RTX toxin 2459895 5174021 CMM_2169 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RTX toxin YP_001222914.1 2453881 R 443906 CDS YP_001222915.1 148273354 5175402 complement(2459892..2461463) 1 NC_009480.1 putative serine/threonine protein kinase (YP_062155.1| serine/ threonine kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696367.1| probable serine/threonine-protein kinase [Bifidobacterium longum NCC2705]; NP_687353.1| serine/threonine protein kinase [Streptococcus agalactiae 2603V/R]). cd00180, S_TKc,Serine/Threonine protein kinases, catalytic domain. Phosphotransferases of the serine or threonine-specific kinase subfamily. pfam00069, Pkinase, Protein kinase domain.; Function unclear; hypothetical protein 2461463 pknG 5175402 pknG Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222915.1 2459892 R 443906 CDS YP_001222916.1 148273355 5173336 complement(2461621..2462946) 1 NC_009480.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2462946 gltA 5173336 gltA Clavibacter michiganensis subsp. michiganensis NCPPB 382 type II citrate synthase YP_001222916.1 2461621 R 443906 CDS YP_001222917.1 148273356 5175139 complement(2463108..2464241) 1 NC_009480.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; N-succinyldiaminopimelate aminotransferase 2464241 5175139 CMM_2172 Clavibacter michiganensis subsp. michiganensis NCPPB 382 N-succinyldiaminopimelate aminotransferase YP_001222917.1 2463108 R 443906 CDS YP_001222918.1 148273357 5173389 complement(2464238..2464558) 1 NC_009480.1 putative ferredoxin (YP_062518.1| ferredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629284.1| ferredoxin [Streptomyces coelicolor A3(2)]). pfam00037,Fer4, 4Fe-4S binding domain. Superfamily includes proteins containing domains which bind to iron-sulfur clusters.; Specificity unclear; hypothetical protein 2464558 fdxB 5173389 fdxB Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222918.1 2464238 R 443906 CDS YP_001222919.1 148273358 5172935 complement(2464599..2465891) 1 NC_009480.1 putative fusion protein; conserved hypothetical protein, putative mycothiol biosynthesis + membrane protein (ZP_00057485.1| COG2120: Uncharacterized proteins,LmbE homologs [Thermobifida fusca]; NP_824314.1| hypothetical protein SAV3138 [Streptomyces avermitilis MA-4680]; YP_062519.1| hypothetical protein Lxx16250 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02585,DUF158, Uncharacterised LmbE-like protein, COG2120. pfam01284, MARVEL, Membrane-associating domain.; Function unclear; hypothetical protein 2465891 5172935 CMM_2174 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222919.1 2464599 R 443906 CDS YP_001222920.1 148273359 5174644 2466135..2467046 1 NC_009480.1 putative Fe2+ permease, OFeT family (NP_827101.1| putative membrane protein [Streptomyces avermitilis MA-4680]; YP_062520.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam03239, FTR1, Iron permease FTR1 family.; Specificity unclear; OFeT family Fe2+ permease 2467046 5174644 CMM_2175 Clavibacter michiganensis subsp. michiganensis NCPPB 382 OFeT family Fe2+ permease YP_001222920.1 2466135 D 443906 CDS YP_001222921.1 148273360 5173524 2467123..2468340 1 NC_009480.1 conserved secreted lipoprotein (YP_062521.1| lipoprotein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827103.1| putative lipoprotein [Streptomyces avermitilis MA-4680]). pfam04302, DUF451, Protein of unknown function (DUF451). Putative lipoprotein.; Function unclear; secreted lipoprotein 2468340 5173524 CMM_2176 Clavibacter michiganensis subsp. michiganensis NCPPB 382 secreted lipoprotein YP_001222921.1 2467123 D 443906 CDS YP_001222922.1 148273361 5175275 2468340..2469671 1 NC_009480.1 conserved hypothetical protein, putative Fe-dependant peroxidase (YP_062522.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827102.1| hypothetical protein SAV5925 [Streptomyces avermitilis MA-4680]). pfam04261, Dyp_perox, Dyp-type peroxidase family. This family of dye-decolourising peroxidases lack a typical heme-binding region.; Function unclear; putative Fe-dependant peroxidase 2469671 5175275 CMM_2177 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe-dependant peroxidase YP_001222922.1 2468340 D 443906 CDS YP_001222923.1 148273362 5173713 complement(2469708..2470217) 1 NC_009480.1 Hypothetical protein; putative secreted protein 2470217 5173713 CMM_2178 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted protein YP_001222923.1 2469708 R 443906 CDS YP_001222924.1 148273363 5173749 complement(2470224..2472131) 1 NC_009480.1 GTP-binding protein typA/bipA homolog (YP_062523.1| GTP-binding protein elongation factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629261.1| putative GTP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00058492.1| COG1217: Predicted membrane GTPase involved in stress response [Thermobifida fusca]). pfam00009,GTP_EFTU, Elongation factor Tu GTP binding domain. pfam03144, GTP_EFTU_D2, Elongation factor Tu domain 2. pfam00679, EFG_C, Elongation factor G C-terminus.; Specificity unclear; GTP-binding protein typA/bipA-like protein 2472131 bipA 5173749 bipA Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP-binding protein typA/bipA-like protein YP_001222924.1 2470224 R 443906 CDS YP_001222925.1 148273364 5173878 complement(2472245..2474098) 1 NC_009480.1 putative peptide ABC transporter, binding protein (YP_062530.1| dipeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822049.1| putative solute-binding dependent transport lipoprotein [Streptomyces avermitilis MA-4680]; NP_217101.1| hypothetical protein Rv2585c [Mycobacterium tuberculosis H37Rv]). pfam00496, SBP_bac_5,Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 2474098 5173878 CMM_2180 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001222925.1 2472245 R 443906 CDS YP_001222926.1 148273365 5173984 complement(2474197..2475888) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (duplicated ATPase domains) (YP_062526.1| oligopeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696512.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]; NP_773349.1| bll6709 [Bradyrhizobium japonicum]). InterPro: AAA ATPase superfamily; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 2475888 5173984 CMM_2181 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001222926.1 2474197 R 443906 CDS YP_001222927.1 148273366 5174441 2475960..2476565 1 NC_009480.1 putative membrane protein (YP_062527.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_056519.1| hypothetical membane-associated protein [Propionibacterium acnes KPA171202]).; Conserved hypothetical protein; hypothetical protein 2476565 5174441 CMM_2182 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222927.1 2475960 D 443906 CDS YP_001222928.1 148273367 5174156 complement(2476619..2477812) 1 NC_009480.1 putative peptide ABC transporter, permease component (YP_062528.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00056958.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Thermobifida fusca]; AAG09259.1| EppC [EDTA-degrading bacterium BNC1]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative oligopeptide ABC transporter, permease component 2477812 5174156 CMM_2183 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oligopeptide ABC transporter, permease component YP_001222928.1 2476619 R 443906 CDS YP_001222929.1 148273368 5173693 complement(2477816..2479342) 1 NC_009480.1 putative peptide ABC transporter, permease component (YP_062529.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824223.1| putative peptide ABC transporter permease protein [Streptomyces avermitilis MA-4680]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 2479342 5173693 CMM_2184 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001222929.1 2477816 R 443906 CDS YP_001222930.1 148273369 5174311 complement(2479521..2481356) 1 NC_009480.1 putative peptide ABC transporter, substrate-binding protein (YP_062530.1| dipeptide porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822049.1| putative solute-binding dependent transport lipoprotein [Streptomyces avermitilis MA-4680]). pfam00496, SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 2481356 5174311 CMM_2185 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001222930.1 2479521 R 443906 CDS YP_001222931.1 148273370 5174768 2481646..2482461 1 NC_009480.1 conserved membran protein (YP_062531.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625656.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam02517, Abi, CAAX amino terminal protease family. Members of this family are probably proteases; the family contains CAAX prenyl protease. prfB: peptide chain release factor 2; Conserved hypothetical protein; membran protein 2482461 5174768 CMM_2186 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membran protein YP_001222931.1 2481646 D 443906 CDS YP_001222932.1 148273371 5175206 2482570..2482977 1 NC_009480.1 hypothetical protein 2482977 5175206 CMM_2187 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222932.1 2482570 D 443906 CDS YP_001222933.1 148273372 5174083 2482974..2484596 1 NC_009480.1 conserved membrane protein, putative transporter of the SSS family (ZP_00293132.1| COG4147: Predicted symporter [Thermobifida fusca]; NP_939157.1| Putative transport membrane protein [Corynebacterium diphtheriae NCTC 13129]). pfam00474, SSF, Sodium:solute symporter family. sss: SSS sodium solute transporter sup; Specificity unclear; SSS family transporter membrane protein 2484596 5174083 CMM_2188 Clavibacter michiganensis subsp. michiganensis NCPPB 382 SSS family transporter membrane protein YP_001222933.1 2482974 D 443906 CDS YP_001222934.1 148273373 5174682 complement(2484641..2485513) 1 NC_009480.1 putative transcriptional regulator, RpiR family (CAF21466.1| transcriptional regulator, rpiR family [Corynebacterium glutamicum ATCC 13032]; NP_346833.1| Transcriptional regulator, RpiR family [Clostridium acetobutylicum]). pfam01418, HTH_6, Helix-turn-helix domain, rpiR family. pfam01380, SIS, SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. InterPro: SIS domain.; Specificity unclear; RpiR family transcriptional regulator 2485513 5174682 CMM_2189 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RpiR family transcriptional regulator YP_001222934.1 2484641 R 443906 CDS YP_001222935.1 148273374 5174128 complement(2485500..2486306) 1 NC_009480.1 putative phosphate/phosphonate ABC transporter,permease component (CAF21467.1| ABC-type phosphate/phosphonate transport system, permease component [Corynebacterium glutamicum ATCC 13032]; NP_691520.1| alkylphosphonate ABC tranporter permease [Oceanobacillus iheyensis HTE831]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative phosphate/phosphonate ABC transporter,permease component 2486306 5174128 CMM_2190 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,permease component YP_001222935.1 2485500 R 443906 CDS YP_001222936.1 148273375 5173838 complement(2486303..2487097) 1 NC_009480.1 putative phosphate/phosphonate ABC transporter,permease component (CAF21468.1| ABC-type phosphate/phosphonate transport system, permease component [Corynebacterium glutamicum ATCC 13032]; ZP_00239895.1| phosphonates transport system permease protein phnE [Bacillus cereus G9241]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative phosphate/phosphonate ABC transporter,permease component 2487097 5173838 CMM_2191 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,permease component YP_001222936.1 2486303 R 443906 CDS YP_001222937.1 148273376 5173239 complement(2487094..2487915) 1 NC_009480.1 putative phosphate/phosphonate ABC transporter, ATP-binding protein (CAF21469.1| ABC-type phosphate/phosphonate transport system, ATPase component [Corynebacterium glutamicum ATCC 13032]; YP_039609.1| putative ABC transport ATP-binding protein [Staphylococcus aureus subsp. aureus MRSA252]).; Specificity unclear; putative phosphate/phosphonate ABC transporter,ATP-binding protein 2487915 5173239 CMM_2192 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,ATP-binding protein YP_001222937.1 2487094 R 443906 CDS YP_001222938.1 148273377 5175538 complement(2487919..2488896) 1 NC_009480.1 putative phosphate/phosphonate ABC transporter,substrate-binding protein (CAF21470.1| ALKYLPHOSPHONATE ABC TRANPORTER (SECRETED PHOSPHATE-BINDING PROTEIN) [Corynebacterium glutamicum ATCC 13032]; NP_765811.1| alkylphosphonate ABC tranporter [Staphylococcus epidermidis ATCC 12228]).; Specificity unclear; putative phosphate/phosphonate ABC transporter,substrate-binding protein 2488896 5175538 CMM_2193 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate/phosphonate ABC transporter,substrate-binding protein YP_001222938.1 2487919 R 443906 CDS YP_001222939.1 148273378 5174045 complement(2488893..2489639) 1 NC_009480.1 putative hydrolase/phosphatase (CAF21471.1| PUTATIVE PHOSPHOGLYCOLATE PHOSPHATASE [Corynebacterium glutamicum ATCC 13032]; NP_879254.1| putative hydrolase [Bordetella pertussis Tohama I]). pfam00702, Hydrolase,haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase/phosphatase 2489639 5174045 CMM_2194 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/phosphatase YP_001222939.1 2488893 R 443906 CDS YP_001222940.1 148273379 5173643 complement(2489862..2492837) 1 NC_009480.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2492837 gcvP 5173643 gcvP Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycine dehydrogenase YP_001222940.1 2489862 R 443906 CDS YP_001222941.1 148273380 5175836 complement(2492834..2493205) 1 NC_009480.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2493205 gcvH 5175836 gcvH Clavibacter michiganensis subsp. michiganensis NCPPB 382 glycine cleavage system protein H YP_001222941.1 2492834 R 443906 CDS YP_001222942.1 148273381 5175751 complement(2493202..2494422) 1 NC_009480.1 putative aminomethyltransferase (Glycine cleavage system T protein) (YP_055458.1| glycine cleavage system protein T [Propionibacterium acnes KPA171202]; Q82JI2|GCST_STRAW Aminomethyltransferase (Glycine cleavage system T protein)). pfam01571, GCV_T, Glycine cleavage T-protein (aminomethyl transferase). InterPro: Glycine cleavage T-protein (aminomethyl transferase).; High confidence in function and specificity; putative aminomethyltransferase (glycine cleavage system T protein) 2494422 gcvT 5175751 gcvT Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aminomethyltransferase (glycine cleavage system T protein) YP_001222942.1 2493202 R 443906 CDS YP_001222943.1 148273382 5175524 complement(2494792..2495247) 1 NC_009480.1 hypothetical protein 2495247 5175524 CMM_2198 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222943.1 2494792 R 443906 CDS YP_001222944.1 148273383 5173515 2495374..2495745 1 NC_009480.1 putative transcriptional regulator (NP_898715.1| putative regulator [Rhodococcus erythropolis]; ZP_00056896.1| COG3682: Predicted transcriptional regulator [Thermobifida fusca]). only weak similarity to: pfam01047, MarR, MarR family.; Specificity unclear; putative transcriptional regulator 2495745 5173515 CMM_2199 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001222944.1 2495374 D 443906 CDS YP_001222945.1 148273384 5173589 complement(2495764..2496534) 1 NC_009480.1 putative copper resistance protein (AAS20064.1| hypothetical protein [Arthrobacter aurescens]; AAP73994.1| putative copper resistance protein (CopC) [Rhodococcus erythropolis]). pfam04234, CopC, Copper resistance protein CopC. CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule.; Conserved hypothetical protein; putative copper resistance protein 2496534 5173589 CMM_2200 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative copper resistance protein YP_001222945.1 2495764 R 443906 CDS YP_001222946.1 148273385 5174606 2496636..2497937 1 NC_009480.1 putative cysteine desulfurase (YP_061934.1| cysteine desulfurase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294076.1| COG0520: Selenocysteine lyase [Thermobifida fusca]). pfam00266, Aminotran_5,Aminotransferase class-V. InterPro: Aminotransferase class-V.; Function unclear; putative cysteine desulfurase 2497937 5174606 CMM_2201 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cysteine desulfurase YP_001222946.1 2496636 D 443906 CDS YP_001222947.1 148273386 5173602 2497934..2498377 1 NC_009480.1 conserved hypothetical protein (YP_061935.1| NifU homolog [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198827.3| COG0822: NifU homolog involved in Fe-S cluster formation [Kineococcus radiotolerans SRS30216]). pfam01592, NifU_N, NifU-like N terminal domain.; hypothetical protein 2498377 5173602 CMM_2202 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222947.1 2497934 D 443906 CDS YP_001222948.1 148273387 5173950 2498457..2498852 1 NC_009480.1 conserved hypothetical protein (ZP_00293644.1| COG3668: Plasmid stabilization system protein [Thermobifida fusca]; NP_961886.1| hypothetical protein MAP2952c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 2498852 5173950 CMM_2203 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222948.1 2498457 D 443906 CDS YP_001222949.1 148273388 5175544 complement(2498892..2501741) 1 NC_009480.1 putative glycosyl hydrolase containing C-terminal fibronectin/RTX domain (NP_811025.1| conserved hypothetical protein [Bacteroides thetaiotaomicron VPI-5482]; NP_695377.1| very narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]). , weak similarity to: COG3507, XynB, Beta-xylosidase; hypothetical protein 2501741 5175544 CMM_2204 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222949.1 2498892 R 443906 CDS YP_001222950.1 148273389 5175823 complement(2501901..2502455) 1 NC_009480.1 putative acetyltransferase (ZP_00209608.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Magnetospirillum magnetotacticum MS-1]; ZP_00293653.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Thermobifida fusca]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2502455 5175823 CMM_2205 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001222950.1 2501901 R 443906 CDS YP_001222951.1 148273390 5173246 2502502..2503578 1 NC_009480.1 hypothetical protein 2503578 5173246 CMM_2206 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222951.1 2502502 D 443906 CDS YP_001222952.1 148273391 5173210 complement(2503597..2504160) 1 NC_009480.1 hypothetical protein 2504160 5173210 CMM_2207 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222952.1 2503597 R 443906 CDS YP_001222953.1 148273392 5174198 complement(2504219..2504623) 1 NC_009480.1 hypothetical protein (only weak similarity to: NP_628387.1| hypothetical protein SCO4212 [Streptomyces coelicolor A3(2)]).; hypothetical protein 2504623 5174198 CMM_2208 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222953.1 2504219 R 443906 CDS YP_001222954.1 148273393 5174648 2504846..2505268 1 NC_009480.1 hypothetical transcriptional regulator, MarR family (only weak similarities: NP_470525.1| ; ZP_00088731.2| COG1846: Transcriptional regulators [Azotobacter vinelandii]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Hypothetical protein; MarR family transcriptional regulator 2505268 5174648 CMM_2209 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001222954.1 2504846 D 443906 CDS YP_001222955.1 148273394 5175510 complement(2505311..2506036) 1 NC_009480.1 conserved hypothetical protein, hypothetical two-component response regulator (NP_769771.1| two-component response regulator [Bradyrhizobium japonicum]; P_00217823.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Burkholderia cepacia R18194]). InterPro: Response regulator receiver domain pfam00072, Response_reg,Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems.; hypothetical protein 2506036 5175510 CMM_2210 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222955.1 2505311 R 443906 CDS YP_001222956.1 148273395 5173276 complement(2506159..2506773) 1 NC_009480.1 hypothetical protein 2506773 5173276 CMM_2211 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222956.1 2506159 R 443906 CDS YP_001222957.1 148273396 5173143 2506863..2508329 1 NC_009480.1 putative amino acid permease, APC family (ZP_00187138.1| COG0531: Amino acid transporters [Rubrobacter xylanophilus DSM 9941]; ZP_00127340.1| COG0531: Amino acid transporters [Pseudomonas syringae pv. syringae B728a]). pfam00324, AA_permease, Amino acid permease. InterPro: Amino acid permease.; Specificity unclear; amino acid permease APC family 2508329 5173143 CMM_2212 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid permease APC family YP_001222957.1 2506863 D 443906 CDS YP_001222958.1 148273397 5173102 2508333..2508782 1 NC_009480.1 conserved hypothetical protein belonging to universal stress protein family (YP_094969.1| universal stress protein A (UspA) [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]; ZP_00359330.1| COG0589: Universal stress protein UspA and related nucleotide-binding proteins [Chloroflexus aurantiacus]). pfam00582,Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents.; Function unclear; hypothetical protein 2508782 5173102 CMM_2213 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222958.1 2508333 D 443906 CDS YP_001222959.1 148273398 5173078 complement(2508793..2509215) 1 NC_009480.1 putative thiol-disulfide oxidoreductase (YP_061316.1| thiol:disulfide interchange protein [Leifsonia xyli subsp. xyli str. CTCB07]; AAS20062.1| hypothetical protein [Arthrobacter aurescens]). InterPro: Thioredoxin.; Function unclear; putative thiol-disulfide oxidoreductase 2509215 5173078 CMM_2214 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thiol-disulfide oxidoreductase YP_001222959.1 2508793 R 443906 CDS YP_001222960.1 148273399 5174015 2509535..2509981 1 NC_009480.1 hypothetical protein with peptidoglycan binding domain pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function.; hypothetical protein 2509981 5174015 CMM_2215 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222960.1 2509535 D 443906 CDS YP_001222961.1 148273400 5173978 complement(2510037..2510237) 1 NC_009480.1 hypothetical protein (CAD47973.1| hypothetical protein [Arthrobacter nicotinovorans]). mobB: molybdopterin-guanine dinucleotide; hypothetical protein 2510237 5173978 CMM_2216 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222961.1 2510037 R 443906 CDS YP_001222962.1 148273401 5173291 2510689..2512101 1 NC_009480.1 putative gamma-aminobutyrate permease, APC family (NP_215036.1| Gamma-aminobutyrate permease [Mycobacterium tuberculosis H37Rv]; T44252 transport protein homolog [imported] - Arthrobacter sp. (strain TE1826)). pfam00324,AA_permease, Amino acid permease. InterPro: Amino acid permease.; Specificity unclear; gamma-aminobutyrate permease 2512101 gabP 5173291 gabP Clavibacter michiganensis subsp. michiganensis NCPPB 382 gamma-aminobutyrate permease YP_001222962.1 2510689 D 443906 CDS YP_001222963.1 148273402 5174552 2512152..2512844 1 NC_009480.1 conserved hypothetical protein, phosphoglycerate mutase family (NP_625941.1| putative phosphatase [Streptomyces coelicolor A3(2)]; NP_336663.1| phosphoglycerate mutase family protein [Mycobacterium tuberculosis CDC1551]). pfam00300, PGAM, Phosphoglycerate mutase family. InterPro: Phosphoglycerate mutase family; Function unclear; hypothetical protein 2512844 5174552 CMM_2218 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222963.1 2512152 D 443906 CDS YP_001222964.1 148273403 5173554 2512868..2513431 1 NC_009480.1 conserved hypothetical protein (NP_827821.1| hypothetical protein SAV6646 [Streptomyces avermitilis MA-4680]; NP_855807.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]).; hypothetical protein 2513431 5173554 CMM_2219 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222964.1 2512868 D 443906 CDS YP_001222965.1 148273404 5173689 2513431..2514198 1 NC_009480.1 conserved hypothetical protein (CAB08660.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_827822.1| hypothetical protein SAV6646 [Streptomyces avermitilis MA-4680]). , pfam00454,PI3_PI4_kinase, Phosphatidylinositol 3- and 4-kinase.; hypothetical protein 2514198 5173689 CMM_2220 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222965.1 2513431 D 443906 CDS YP_001222966.1 148273405 5172985 2514367..2515011 1 NC_009480.1 hypothetical protein , weak similarity to: COG4969,PilA, Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; hypothetical protein 2515011 5172985 CMM_2221 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222966.1 2514367 D 443906 CDS YP_001222967.1 148273406 5173194 complement(2515482..2515967) 1 NC_009480.1 hypothetical protein (AAN12593.1| gp32 [Mycobacteriophage Che9c]; YP_113190.1| Hypothetical protein MCA0678 [Methylococcus capsulatus str. Bath]). ,pfam06114, DUF955, Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function.; hypothetical protein 2515967 5173194 CMM_2222 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222967.1 2515482 R 443906 CDS YP_001222968.1 148273407 5173129 complement(2516137..2517210) 1 NC_009480.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2517210 5173129 CMM_2223 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GTP-dependent nucleic acid-binding protein EngD YP_001222968.1 2516137 R 443906 CDS YP_001222969.1 148273408 5173060 2517310..2517939 1 NC_009480.1 putative 3'-5' exonuclease (YP_062544.1| DNA polymerase III, epsilon subunit [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293652.1| COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [Thermobifida fusca]). pfam00929, Exonuc_X-T, Exonuclease. This family includes a variety of exonuclease proteins,such as ribonuclease T and the epsilon subunit of DNA polymerase III.; Function unclear; hypothetical protein 2517939 5173060 CMM_2224 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222969.1 2517310 D 443906 CDS YP_001222970.1 148273409 5173070 2518006..2519385 1 NC_009480.1 conserved hypothetical protein (YP_062546.1| Hypothetical protein Lxx16660 [Leifsonia xyli subsp. xyli str. CTCB07]; Q9CLG7|RMUC_PASMU DNA recombination protein rmuC homolog; ZP_00134138.1| COG1322: Uncharacterized protein conserved in bacteria [Actinobacillus pleuropneumoniae serovar 1 str. 4074]). pfam02646, RmuC,RmuC family. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures.; Family membership; hypothetical protein 2519385 5173070 CMM_2225 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222970.1 2518006 D 443906 CDS YP_001222971.1 148273410 5173066 2519491..2520516 1 NC_009480.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2520516 fbaA 5173066 fbaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 fructose-bisphosphate aldolase YP_001222971.1 2519491 D 443906 CDS YP_001222972.1 148273411 5173171 complement(2520612..2521448) 1 NC_009480.1 hypothetical membrane protein (YP_062549.1| Hypothetical protein Lxx16690 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2521448 5173171 CMM_2227 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222972.1 2520612 R 443906 CDS YP_001222973.1 148273412 5175201 complement(2521445..2522434) 1 NC_009480.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2522434 ispH 5175201 ispH Clavibacter michiganensis subsp. michiganensis NCPPB 382 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_001222973.1 2521445 R 443906 CDS YP_001222974.1 148273413 5174783 2522582..2523898 1 NC_009480.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2523898 xseA 5174783 xseA Clavibacter michiganensis subsp. michiganensis NCPPB 382 exodeoxyribonuclease VII large subunit YP_001222974.1 2522582 D 443906 CDS YP_001222975.1 148273414 5174106 2523909..2524151 1 NC_009480.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2524151 xseB 5174106 xseB Clavibacter michiganensis subsp. michiganensis NCPPB 382 exodeoxyribonuclease VII small subunit YP_001222975.1 2523909 D 443906 CDS YP_001222976.1 148273415 5174125 2524154..2524861 1 NC_009480.1 conserved hypothetical protein (NP_629200.1| putative secreted protein [Streptomyces coelicolor A3(2)]; ZP_00225733.1| hypothetical protein Krad06004532 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2524861 5174125 CMM_2231 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222976.1 2524154 D 443906 CDS YP_001222977.1 148273416 5173730 2524858..2525520 1 NC_009480.1 putative carbonic anhydrase (YP_062554.1| carbonic anhydrase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_338238.1| carbonic anhydrase [Mycobacterium tuberculosis CDC1551]). pfam00484, Pro_CA, Carbonic anhydrase.; Function unclear; putative carbonic anhydrase 2525520 cynT 5173730 cynT Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carbonic anhydrase YP_001222977.1 2524858 D 443906 CDS YP_001222978.1 148273417 5174358 2525602..2527026 1 NC_009480.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 2527026 fumC 5174358 fumC Clavibacter michiganensis subsp. michiganensis NCPPB 382 fumarate hydratase YP_001222978.1 2525602 D 443906 CDS YP_001222979.1 148273418 5174352 2527058..2527327 1 NC_009480.1 hypothetical protein 2527327 5174352 CMM_2234 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222979.1 2527058 D 443906 CDS YP_001222980.1 148273419 5175344 complement(2527411..2528766) 1 NC_009480.1 putative ATPase (YP_062557.1| PhoH-like protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824412.1| putative ATP-binding protein [Streptomyces avermitilis MA-4680]). pfam01850, PIN, PIN domain. This PIN (PilT N terminus) domain is a compact domain of about 100 amino acids. pfam02562, PhoH, PhoH-like protein. PhoH is a cytoplasmic protein and predicted ATPase that is induced by phosphate starvation.; Function unclear; putative ATPase 2528766 5175344 CMM_2235 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001222980.1 2527411 R 443906 CDS YP_001222981.1 148273420 5175916 complement(2528994..2529779) 1 NC_009480.1 putative undecaprenyl diphosphate synthase (YP_062559.1| undecaprenyl pyrophosphate synthetase [Leifsonia xyli subsp. xyli str. CTCB07]; BAD59670.1| putative undecaprenyl pyrophosphate synthetase [Nocardia farcinica]). , pfam01255, UPP_synthetase, Putative undecaprenyl diphosphate synthase. Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase. , uppS: undecaprenyl diphosphate synthas; High confidence in function and specificity; putative undecaprenyl diphosphate synthase 2529779 uppS2 5175916 uppS2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative undecaprenyl diphosphate synthase YP_001222981.1 2528994 R 443906 CDS YP_001222982.1 148273421 5173254 2529861..2530616 1 NC_009480.1 conserved membrane protein, HlyIII family (YP_062560.1| hemolysin III family protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629130.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_696186.1| conserved hypothetical protein [Bifidobacterium longum NCC2705]). , pfam03006, UPF0073,Uncharacterised protein family (Hly-III / UPF0073). Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It is not clear if all the members of this family are hemolysins.; Function unclear; HlyIII family membrane protein 2530616 5173254 CMM_2237 Clavibacter michiganensis subsp. michiganensis NCPPB 382 HlyIII family membrane protein YP_001222982.1 2529861 D 443906 CDS YP_001222983.1 148273422 5174932 complement(2530641..2532020) 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (ZP_00049406.2| COG1653: ABC-type sugar transport system, periplasmic component [Magnetospirillum magnetotacticum MS-1]; CAB03653.1| PROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB [Mycobacterium tuberculosis H37Rv]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 2532020 5174932 CMM_2238 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001222983.1 2530641 R 443906 CDS YP_001222984.1 148273423 5173918 complement(2532082..2532996) 1 NC_009480.1 putative glycerol ABC transporter, permease component (ZP_00356561.1| COG0395: ABC-type sugar transport system, permease component [Chloroflexus aurantiacus]; NP_600603.1| ABC-type transporter, permease component [Corynebacterium glutamicum ATCC 13032]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glycerol ABC transporter, permease component 2532996 5173918 CMM_2239 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerol ABC transporter, permease component YP_001222984.1 2532082 R 443906 CDS YP_001222985.1 148273424 5175228 complement(2532993..2533982) 1 NC_009480.1 putative glycerol ABC transporter, permease component (CAB03651.1| PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPA [Mycobacterium tuberculosis H37Rv]; NP_738124.1| putative ABC transporter permease protein [Corynebacterium efficiens YS-314]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative glycerol ABC transporter, permease component 2533982 5175228 CMM_2240 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerol ABC transporter, permease component YP_001222985.1 2532993 R 443906 CDS YP_001222986.1 148273425 5173891 complement(2534162..2534506) 1 NC_009480.1 hypothetical membrane protein (AAS20077.1| membrane protein [Arthrobacter aurescens]; YP_062561.1| Hypothetical protein Lxx16880 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2534506 5173891 CMM_2241 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222986.1 2534162 R 443906 CDS YP_001222987.1 148273426 5174635 complement(2534506..2535387) 1 NC_009480.1 conserved hypothetical protein (NP_737662.1| hypothetical protein CE1052 [Corynebacterium efficiens YS-314]; CAA17198.1| Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase)[Mycobacterium tuberculosis H37Rv]). pfam02585, DUF158, Uncharacterised LmbE-like protein, COG2120. 3mg: DNA-3-methyladenine glycosylase; hypothetical protein 2535387 5174635 CMM_2242 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222987.1 2534506 R 443906 CDS YP_001222988.1 148273427 5174238 2535454..2535936 1 NC_009480.1 hypothetical protein (YP_055275.1| hypothetical protein PPA0562 [Propionibacterium acnes KPA171202]; BAD59677.1| hypothetical protein [Nocardia farcinica]).; hypothetical protein 2535936 5174238 CMM_2243 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222988.1 2535454 D 443906 CDS YP_001222989.1 148273428 5174370 2535997..2536485 1 NC_009480.1 transcription elongation factor (Transcript cleavage factor greA)(YP_062562.1| transcription elongation factor [Leifsonia xyli subsp. xyli str. CTCB07]; Q9ADK2|GREA_STRCO Transcription elongation factor greA (Transcript cleavage factor greA)). pfam03449,GreA_GreB_N, Prokaryotic transcription elongation factor,GreA/GreB, N-terminal domain. pfam01272, GreA_GreB,Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain.; High confidence in function and specificity; transcription elongation factor GreA 2536485 greA 5174370 greA Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcription elongation factor GreA YP_001222989.1 2535997 D 443906 CDS YP_001222990.1 148273429 5174762 complement(2536552..2537820) 1 NC_009480.1 catalyzes the formation of 2-oxobutanoate from L-threonine; threonine dehydratase 2537820 ilvA 5174762 ilvA Clavibacter michiganensis subsp. michiganensis NCPPB 382 threonine dehydratase YP_001222990.1 2536552 R 443906 CDS YP_001222991.1 148273430 5173535 complement(2537925..2539160) 1 NC_009480.1 conserved membrane protein, AI-E2 family (YP_062564.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; BAD60345.1| hypothetical protein [Nocardia farcinica])., pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function.; AI-E2 family membrane protein 2539160 5173535 CMM_2246 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AI-E2 family membrane protein YP_001222991.1 2537925 R 443906 CDS YP_001222992.1 148273431 5175039 2539261..2540511 1 NC_009480.1 conserved hypothetical protein (YP_062567.1| Hypothetical protein Lxx16960 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00194535.1| COG3214: Uncharacterized protein conserved in bacteria [Mesorhizobium sp. BNC1]). pfam06224, DUF1006, Protein of unknown function (DUF1006). Family of conserved bacterial proteins with unknown function. aroC: chorismate synthase; hypothetical protein 2540511 5175039 CMM_2247 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222992.1 2539261 D 443906 CDS YP_001222993.1 148273432 5173873 complement(2540522..2541088) 1 NC_009480.1 conserved hypothetical protein (YP_062568.1| LemA-like protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787140.1| hypothetical protein TWT012 [Tropheryma whipplei str. Twist]). pfam04011, LemA, LemA family. The members of this family are related to the LemA protein.; hypothetical protein 2541088 5173873 CMM_2248 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222993.1 2540522 R 443906 CDS YP_001222994.1 148273433 5175028 complement(2541091..2542593) 1 NC_009480.1 putative beta-glucosidase (Gentiobiase) (Cellobiase) (NP_826775.1| putative beta-glucosidase [Streptomyces avermitilis MA-4680]; AAN05440.1| beta-glycosidase [Thermus filiformis]). pfam00232,Glyco_hydro_1, Glycosyl hydrolase family 1. InterPro: Glycoside hydrolase family 1; Specificity unclear; putative beta-glucosidase 2542593 bglL 5175028 bglL Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-glucosidase YP_001222994.1 2541091 R 443906 CDS YP_001222995.1 148273434 5175420 2542734..2545028 1 NC_009480.1 Region start changed from 2542743 to 2542734 (9 bases); hypothetical protein 2545028 5175420 CMM_2250 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222995.1 2542734 D 443906 CDS YP_001222996.1 148273435 5173721 2545161..2546603 1 NC_009480.1 putative amino acid permease, APC family (NP_625236.1| putative amino acid transporter protein [Streptomyces coelicolor A3(2)]; ZP_00187751.1| COG0531: Amino acid transporters [Rubrobacter xylanophilus DSM 9941]). pfam00324, AA_permease, Amino acid permease.; Specificity unclear; amino acid permease APC family 2546603 5173721 CMM_2251 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid permease APC family YP_001222996.1 2545161 D 443906 CDS YP_001222997.1 148273436 5175865 complement(2546679..2547620) 1 NC_009480.1 conserved hypothetical protein (ZP_00227307.1| hypothetical protein Krad06001366 [Kineococcus radiotolerans SRS30216]; ZP_00029551.1| hypothetical protein [Burkholderia fungorum]; NP_051649.1| dessication-associated protein [Deinococcus radiodurans R1]).; Function unclear; hypothetical protein 2547620 5175865 CMM_2252 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222997.1 2546679 R 443906 CDS YP_001222998.1 148273437 5175084 complement(2547805..2550366) 1 NC_009480.1 conserved hypothetical protein contains two domains: N-terminal: putative endoglucanase domain (CAD47882.1| hypothetical protein [Arthrobacter nicotinovorans]). C-terminal: pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes (NP_946456.1| possible OpgC protein, require for succinylation of osmoregulated periplasmic glucans [Rhodopseudomonas palustris CGA009]; NP_771053.1| bll4413 [Bradyrhizobium japonicum USDA 110]).; Function unclear; hypothetical protein 2550366 5175084 CMM_2253 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001222998.1 2547805 R 443906 CDS YP_001222999.1 148273438 5174904 complement(2550438..2550872) 1 NC_009480.1 putative anti-sigma regulatory factor (Ser/Thr protein kinase) (NP_737815.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_681341.1| sigma-B activity negative regulator [Thermosynechococcus elongatus BP-1]).; Function unclear; putative anti-sigma regulatory factor (Ser/Thr protein kinase) 2550872 5174904 CMM_2254 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anti-sigma regulatory factor (Ser/Thr protein kinase) YP_001222999.1 2550438 R 443906 CDS YP_001223000.1 148273439 5175307 complement(2550877..2551215) 1 NC_009480.1 putative anti-sigma factor antagonist (ZP_00357937.1| COG1366: Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Chloroflexus aurantiacus]; NP_737814.1| putative anti-sigma factor antagonist [Corynebacterium efficiens YS-314]). pfam01740,STAS, STAS domain. The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.; Function unclear; putative anti-sigma factor antagonist 2551215 5175307 CMM_2255 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative anti-sigma factor antagonist YP_001223000.1 2550877 R 443906 CDS YP_001223001.1 148273440 5172927 complement(2551212..2553203) 1 NC_009480.1 putative glycosyl transferase (NP_737812.1 + NP_737813.1|| putative cellulose synthase catalytic subunit [Corynebacterium efficiens YS-314]; ZP_00020665.2| COG1215: Glycosyltransferases, probably involved in cell wall biogenesis [Chloroflexus aurantiacus]). pfam00535, Glycos_transf_2, Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose,dolichol phosphate and teichoic acids. only weak similarity to: pfam03552, Cellulose_synt, Cellulose synthase.; Function unclear; putative glycosyl transferase 2553203 5172927 CMM_2256 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001223001.1 2551212 R 443906 CDS YP_001223002.1 148273441 5173820 complement(2553200..2554396) 1 NC_009480.1 Sensory box histidine kinase/response regulator (NP_737811.1| putative regulatory protein [Corynebacterium efficiens YS-314]). , contains two domains: N-terminal,pfam01590, GAF, GAF domain. Domain present in phytochromes and cGMP-specific phosphodiesterases (ZP_00265410.1| COG2199: FOG: GGDEF domain [Pseudomonas fluorescens PfO-1]; ZP_00052301.2| COG2203: FOG: GAF domain [Magnetospirillum magnetotacticum MS-1]). , C-terminal,COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; smart00331, PP2C_SIG, Sigma factor PP2C-like phosphatases (ZP_00187433.1| COG2208: Serine phosphatase RsbU,regulator of sigma subunit; ZP_00356055.1| COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain [Chloroflexus aurantiacus]).; Conserved hypothetical protein; putative protein kinase/phosphatase regulator hybrid protein 2554396 5173820 CMM_2257 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein kinase/phosphatase regulator hybrid protein YP_001223002.1 2553200 R 443906 CDS YP_001223003.1 148273442 5175833 2554575..2555729 1 NC_009480.1 putative membrane-bound acyltransferase (ZP_00107696.1| COG1835: Predicted acyltransferases [Nostoc punctiforme PCC 73102]; AAO54531.1| acyltransferase family protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam01757, Acyl_transf_3,Acyltransferase family. This family includes a range of acyltransferase enzymes.; Specificity unclear; putative membrane-bound acyltransferase 2555729 5175833 CMM_2258 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound acyltransferase YP_001223003.1 2554575 D 443906 CDS YP_001223004.1 148273443 5174832 complement(2555945..2557432) 1 NC_009480.1 putative NADH dehydrogenase (YP_062580.1| NADH dehydrogenase, type 2 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_631162.1| putative dehydrogenase [Streptomyces coelicolor A3(2)]). , pfam00070, Pyr_redox,Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.; Specificity unclear; putative NADH dehydrogenase 2557432 5174832 CMM_2259 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NADH dehydrogenase YP_001223004.1 2555945 R 443906 CDS YP_001223005.1 148273444 5174115 complement(2557470..2558753) 1 NC_009480.1 putative serine peptidase, family S8 (YP_062581.1| serine protease [Leifsonia xyli subsp. xyli str. CTCB07]; NP_827909.1| putative secreted serine proteinase [Streptomyces avermitilis MA-4680]). pfam00082,Peptidase_S8, Subtilase family. Subtilases are a family of serine proteases. InterPro: Serine proteases subtilase family.; Function unclear; serine peptidase 2558753 5174115 CMM_2260 Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine peptidase YP_001223005.1 2557470 R 443906 CDS YP_001223006.1 148273445 5175003 complement(2558750..2559265) 1 NC_009480.1 conserved hypothetical protein (YP_062582.1| Hypothetical protein Lxx17160 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789712.1| hypothetical protein TW791 [Tropheryma whipplei TW08/27]). pfam04417, DUF501, Protein of unknown function (DUF501). Family of uncharacterised bacterial proteins. TIGR00162: conserved hypothetical protei; hypothetical protein 2559265 5175003 CMM_2261 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223006.1 2558750 R 443906 CDS YP_001223007.1 148273446 5175810 complement(2559262..2559834) 1 NC_009480.1 conserved hypothetical protein (YP_062583.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824709.1| hypothetical protein SAV3532 [Streptomyces avermitilis MA-4680]). pfam04977, DivIC,Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation.; hypothetical protein 2559834 5175810 CMM_2262 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223007.1 2559262 R 443906 CDS YP_001223008.1 148273447 5175418 complement(2559922..2561202) 1 NC_009480.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2561202 eno 5175418 eno Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphopyruvate hydratase YP_001223008.1 2559922 R 443906 CDS YP_001223009.1 148273448 5174037 complement(2561319..2562626) 1 NC_009480.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2562626 hisS 5174037 hisS Clavibacter michiganensis subsp. michiganensis NCPPB 382 histidyl-tRNA synthetase YP_001223009.1 2561319 R 443906 CDS YP_001223010.1 148273449 5175200 complement(2562639..2563280) 1 NC_009480.1 putative transcriptional regulator, TetR-family (YP_061371.1| transcriptional regulator, TetR family [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228510.1| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_824937.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 2563280 5175200 CMM_2265 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223010.1 2562639 R 443906 CDS YP_001223011.1 148273450 5175103 complement(2563435..2564199) 1 NC_009480.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 2564199 5175103 CMM_2266 Clavibacter michiganensis subsp. michiganensis NCPPB 382 nucleoside triphosphate pyrophosphohydrolase YP_001223011.1 2563435 R 443906 CDS YP_001223012.1 148273451 5175190 2564307..2565536 1 NC_009480.1 putative Na+/H+ antiporter, NhaA family (NP_789716.1| putative sodium/proton antiporter [Tropheryma whipplei TW08/27]; AAL15616.1| sodium/proton antiporter [Streptomyces antibioticus]). , pfam06965,Na_H_antiport_1, Na+/H+ antiporter 1. , InterPro: Na+/H+ exchanger.; High confidence in function and specificity; NhaA family Na+/H+ antiporter 2565536 nhaA2 5175190 nhaA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 NhaA family Na+/H+ antiporter YP_001223012.1 2564307 D 443906 CDS YP_001223013.1 148273452 5174686 complement(2565560..2569192) 1 NC_009480.1 putative transcription-repair coupling factor (superfamily II helicase) (BAD59727.1| putative transcription-repair coupling factor [Nocardia farcinica]; ZP_00059332.1| COG1197: Transcription-repair coupling factor (superfamily II helicase) [Thermobifida fusca]; NP_824726.1| putative transcriptional-repair coupling factor [Streptomyces avermitilis MA-4680]). NECESSARY FOR STRAND-SPECIFIC REPAIR. A LESION IN THE TEMPLATE STRAND BLOCKS THE RNA POLYMERASE COMPLEX (RNAP). THE RNAP-DNA-RNA COMPLEX IS SPECIFICALLY RECOGNIZED BY TRCF WHICH RELEASES RNAP AND THE TRUNCATED TRANSCRIPT; THE TCRF MAY REPLACE RNAP AT THE LESION SITE AND THEN RECRUIT THE UVRA/B/C REPAIR SYSTEM (BY SIMILARITY). pfam02559,CarD_TRCF, CarD-like/TRCF domain. pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain. pfam03461, TRCF, TRCF domain. InterPro: Transcription-repair coupling factor.; High confidence in function and specificity; putative transcription-repair coupling factor 2569192 mfdA 5174686 mfdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcription-repair coupling factor YP_001223013.1 2565560 R 443906 CDS YP_001223014.1 148273453 5173869 complement(2569281..2569868) 1 NC_009480.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2569868 pthA 5173869 pthA Clavibacter michiganensis subsp. michiganensis NCPPB 382 peptidyl-tRNA hydrolase YP_001223014.1 2569281 R 443906 CDS YP_001223015.1 148273454 5175035 complement(2570009..2570653) 1 NC_009480.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 2570653 rplY 5175035 rplY Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L25/general stress protein Ctc YP_001223015.1 2570009 R 443906 CDS YP_001223016.1 148273455 5175399 complement(2570824..2572833) 1 NC_009480.1 putative gluconokinase/dehydrogenase two-domain protein N-terminal: COG3265, GntK, Gluconate kinase (NP_738994.1| putative gluconokinase [Corynebacterium efficiens YS-314]; ZP_00057417.1| COG3265: Gluconate kinase [Thermobifida fusca]). C-terminal: COG0673, MviM,Predicted dehydrogenases and related proteins; pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold, pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain. (NP_622316.1| predicted dehydrogenases and related proteins [Thermoanaerobacter tengcongensis]; NP_782809.1| lipopolysaccharide biosynthesis protein [Clostridium tetani E88]). InterPro: Shikimate kinase; Function unclear; putative gluconokinase/dehydrogenase 2572833 5175399 CMM_2271 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative gluconokinase/dehydrogenase YP_001223016.1 2570824 R 443906 CDS YP_001223017.1 148273456 5174551 2572917..2574371 1 NC_009480.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2574371 gndA2 5174551 gndA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 6-phosphogluconate dehydrogenase YP_001223017.1 2572917 D 443906 CDS YP_001223018.1 148273457 5173364 2574441..2574815 1 NC_009480.1 hypothetical protein (YP_062601.1| Hypothetical protein Lxx17390 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2574815 5173364 CMM_2273 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223018.1 2574441 D 443906 CDS YP_001223019.1 148273458 5173779 complement(2574861..2575838) 1 NC_009480.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2575838 prsA 5173779 prsA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribose-phosphate pyrophosphokinase YP_001223019.1 2574861 R 443906 CDS YP_001223020.1 148273459 5175349 complement(2575853..2577397) 1 NC_009480.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 2577397 glmU 5175349 glmU Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_001223020.1 2575853 R 443906 CDS YP_001223021.1 148273460 5175777 2577650..2578153 1 NC_009480.1 putative transcriptional regulator, MarR family (YP_062606.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627350.1| putative MarR-family regulator [Streptomyces coelicolor A3(2)]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 2578153 5175777 CMM_2276 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223021.1 2577650 D 443906 CDS YP_001223022.1 148273461 5175224 complement(2578182..2578538) 1 NC_009480.1 conserved hypothetical protein, putative DNA-binding protein (ZP_00352245.1| COG1734: DnaK suppressor protein [Kineococcus radiotolerans SRS30216]; ZP_00238743.1| DnaK suppressor protein [Bacillus cereus G9241]). pfam01258, zf-dskA_traR, Prokaryotic dksA/traR C4-type zinc finger.; putative DNA-binding protein 2578538 5175224 CMM_2277 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-binding protein YP_001223022.1 2578182 R 443906 CDS YP_001223023.1 148273462 5174221 complement(2578549..2579556) 1 NC_009480.1 putative monooxygenase (NP_601510.1| coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase [Corynebacterium glutamicum ATCC 13032]; NP_767884.1| flavin dependant oxidoreductase [Bradyrhizobium japonicum USDA 110]). pfam00296,Bac_luciferase, Luciferase-like monooxygenase.; Function unclear; putative monooxygenase 2579556 5174221 CMM_2278 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001223023.1 2578549 R 443906 CDS YP_001223024.1 148273463 5175326 complement(2579559..2580359) 1 NC_009480.1 conserved membrane protein, LysE transporter family (CAA98398.1| PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_638302.1| membrane transport protein [Xanthomonas campestris pv. campestris str. ATCC 33913]). pfam01810, LysE, LysE type translocator. This family consists of various hypothetical proteins and an l-lysine exporter LysE from Corynebacterium glutamicum which is proposed to be the first of a novel family of translocators.; Function unclear; amino acid transporter LysE 2580359 5175326 CMM_2279 Clavibacter michiganensis subsp. michiganensis NCPPB 382 amino acid transporter LysE YP_001223024.1 2579559 R 443906 CDS YP_001223025.1 148273464 5174836 2580429..2581325 1 NC_009480.1 putative transcriptional regulator, LysR family (NP_822296.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; YP_116352.1| putative transcriptional regulator [Nocardia farcinica]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466,LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 2581325 5174836 CMM_2280 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001223025.1 2580429 D 443906 CDS YP_001223026.1 148273465 5175702 complement(2581363..2582022) 1 NC_009480.1 putative metal ABC transporter , permease component (YP_062479.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121550.1| COG2011: ABC-type metal ion transport system, permease component [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative metal ABC transporter, permease component 2582022 5175702 CMM_2281 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, permease component YP_001223026.1 2581363 R 443906 CDS YP_001223027.1 148273466 5174747 complement(2582024..2583061) 1 NC_009480.1 putative metal ABC transporter , ATP-binding protein (YP_062480.1| glycine betaine/proline porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696132.1| ATP binding protein of ABC transporter [Bifidobacterium longum NCC2705]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative metal ABC transporter, ATP-binding protein 2583061 5174747 CMM_2282 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, ATP-binding protein YP_001223027.1 2582024 R 443906 CDS YP_001223028.1 148273467 5174423 complement(2583058..2583990) 1 NC_009480.1 putative metal ABC transporter, substrate-binding protein (ZP_00121548.1| COG1464: ABC-type metal ion transport system, periplasmic component/surface antigen [Bifidobacterium longum DJO10A]; YP_120623.1| putative lipoprotein [Nocardia farcinica]). pfam03180,Lipoprotein_9, NLPA lipoprotein. This family of bacterial lipoproteins contains several antigenic members, that may be involved in bacterial virulence. Their precise function is unknown. However they are probably distantly related to pfam00497 which are solute binding proteins.; Specificity unclear; putative metal ABC transporter, substrate-binding protein 2583990 5174423 CMM_2283 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, substrate-binding protein YP_001223028.1 2583058 R 443906 CDS YP_001223029.1 148273468 5174181 2584336..2585238 1 NC_009480.1 hypothetical protein 2585238 5174181 CMM_2284 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223029.1 2584336 D 443906 CDS YP_001223030.1 148273469 5174627 complement(2585251..2587068) 1 NC_009480.1 putative ABC transporter, duplicated ATP-binding protein (YP_062608.1| oleandomycin resistance ATPase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_960308.1| hypothetical protein MAP1374c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00059317.1| COG0488: ATPase components of ABC transporters with duplicated ATPase domains [Thermobifida fusca]). pfam00005, ABC_tran,ABC transporter (twice). InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter, duplicated ATP-binding protein 2587068 5174627 CMM_2285 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, duplicated ATP-binding protein YP_001223030.1 2585251 R 443906 CDS YP_001223031.1 148273470 5173852 2587139..2588842 1 NC_009480.1 putative DNA recombinase/integrase (BAA07372.1| ORF469 protein [Bacteriophage R4]; CAB09083.1| Probable phiRv1 integrase [Mycobacterium tuberculosis H37Rv]; NP_825645.1| putative integrase/recombinase [Streptomyces avermitilis MA-4680]).; Specificity unclear; putative integrase/recombinase 2588842 intA 5173852 intA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative integrase/recombinase YP_001223031.1 2587139 D 443906 CDS YP_001223032.1 148273471 5175958 complement(2589829..2591448) 1 NC_009480.1 conserved hypothetical protein, ftsK homolog (NP_902149.1| cell division ftsk transmembrane protein [Chromobacterium violaceum ATCC 12472]; ZP_00217369.1| COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Burkholderia cepacia R18194]). pfam01580,FtsK_SpoIIIE, FtsK/SpoIIIE family. FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif.; Family membership; hypothetical protein 2591448 5175958 CMM_2287 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223032.1 2589829 R 443906 CDS YP_001223033.1 148273472 5174236 complement(2591441..2591923) 1 NC_009480.1 hypothetical protein 2591923 5174236 CMM_2288 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223033.1 2591441 R 443906 CDS YP_001223034.1 148273473 5175169 complement(2592071..2593186) 1 NC_009480.1 hypothetical protein 2593186 5175169 CMM_2289 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223034.1 2592071 R 443906 CDS YP_001223035.1 148273474 5174942 2594184..2594678 1 NC_009480.1 putative endonuclease (NP_821177.1| putative endonuclease VII [Streptomyces avermitilis MA-4680]; AAN12731.1| gp89 [Mycobacteriophage Omega]) pfam02945,Endonuclease_7, Recombination endonuclease VII.; Function unclear; putative endonuclease 2594678 5174942 CMM_2290 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endonuclease YP_001223035.1 2594184 D 443906 CDS YP_001223036.1 148273475 5174704 complement(2595263..2596027) 1 NC_009480.1 putative endonuclease (NP_487703.1| unknown protein [Nostoc sp. PCC 7120]; CAD54902.1| putative lysogenic conversion protein [Bacteriophage P2-EC46]). pfam01844,HNH, HNH endonuclease.; Hypothetical protein; putative endonuclease 2596027 5174704 CMM_2291 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endonuclease YP_001223036.1 2595263 R 443906 CDS YP_001223037.1 148273476 5174504 complement(2596073..2597857) 1 NC_009480.1 hypothetical protein (NP_744426.1| hypothetical protein PP2277 [Pseudomonas putida KT2440]); hypothetical protein 2597857 5174504 CMM_2292 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223037.1 2596073 R 443906 CDS YP_001223038.1 148273477 5175012 2598067..2598270 1 NC_009480.1 hypothetical protein 2598270 5175012 CMM_2293 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223038.1 2598067 D 443906 CDS YP_001223039.1 148273478 5174255 2598267..2598668 1 NC_009480.1 hypothetical protein 2598668 5174255 CMM_2294 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223039.1 2598267 D 443906 CDS YP_001223040.1 148273479 5175337 2599259..2599699 1 NC_009480.1 hypothetical secreted protein, putative pilin (NP_935571.1| type IV pilin PilA [Vibrio vulnificus YJ016]; ZP_00224593.1| COG4969: Tfp pilus assembly protein, major pilin PilA [Burkholderia cepacia R1808]). weak similarity to: COG4969, PilA, Tfp pilus assembly protein, major pilin PilA; pfam00114, Pilin, Pilin (bacterial filament).; Hypothetical protein; pilin 2599699 5175337 CMM_2295 Clavibacter michiganensis subsp. michiganensis NCPPB 382 pilin YP_001223040.1 2599259 D 443906 CDS YP_001223041.1 148273480 5174581 complement(2600459..2601316) 1 NC_009480.1 hypothetical protein 2601316 5174581 CMM_2296 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223041.1 2600459 R 443906 CDS YP_001223042.1 148273481 5175082 2602014..2602694 1 NC_009480.1 putative recombinase/resolvase (AAG24402.1| site-specific recombinase [Actinobacillus actinomycetemcomitans]; CAE46772.1| recombinase [Yersinia enterocolitica]). pfam00239, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family (this family) contains the active site and the dimer interface.; Hypothetical protein; putative resolvase 2602694 5175082 CMM_2297 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative resolvase YP_001223042.1 2602014 D 443906 CDS YP_001223043.1 148273482 5175340 2602691..2602870 1 NC_009480.1 hypothetical protein 2602870 5175340 CMM_2298 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223043.1 2602691 D 443906 CDS YP_001223044.1 148273483 5174715 2602854..2603441 1 NC_009480.1 hypothetical protein (only weak similarities to endonucleases: pfam01541, GIY-YIG, GIY-YIG catalytic domain. This domain called GIY-YIG is found in the amino terminal region of excinuclease abc subunit c (uvrC),bacteriophage T4 endonucleases segA, segB, segC, segD and segE; it is also found in putative endonucleases encoded by group I introns of fungi and phage; AAD42655.2| SegB homing endonuclease [Enterobacteria phage T4]).; hypothetical protein 2603441 5174715 CMM_2299 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223044.1 2602854 D 443906 CDS YP_001223045.1 148273484 5175977 2603570..2604280 1 NC_009480.1 hypothetical protein 2604280 5175977 CMM_2300 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223045.1 2603570 D 443906 CDS YP_001223046.1 148273485 5173425 2605923..2606174 1 NC_009480.1 hypothetical protein 2606174 5173425 CMM_2301 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223046.1 2605923 D 443906 CDS YP_001223047.1 148273486 5175654 complement(2606235..2606807) 1 NC_009480.1 hypothetical protein (weak similarities to: NP_607806.1| conserved hypothetical phage protein [Streptococcus pyogenes MGAS8232]). weak similarity to: smart00470, ParB, ParB-like nuclease domain.; hypothetical protein 2606807 5175654 CMM_2302 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223047.1 2606235 R 443906 CDS YP_001223048.1 148273487 5174168 complement(2607098..2607688) 1 NC_009480.1 hypothetical protein 2607688 5174168 CMM_2303 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223048.1 2607098 R 443906 CDS YP_001223049.1 148273488 5175602 complement(2607802..2608245) 1 NC_009480.1 hypothetical protein 2608245 5175602 CMM_2304 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223049.1 2607802 R 443906 CDS YP_001223050.1 148273489 5173935 2609051..2610355 1 NC_009480.1 putative multidrug-efflux MFS permease (NP_792949.1| multidrug resistance protein, putative [Pseudomonas syringae pv. tomato str. DC3000]; ZP_00363247.1| COG0477: Permeases of the major facilitator superfamily [Polaromonas sp. JS666]). pfam00083, Sugar_tr,Sugar (and other) transporter. InterPro: General substrate transporters.; Specificity unclear; putative multidrug-efflux MFS permease 2610355 5173935 CMM_2305 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug-efflux MFS permease YP_001223050.1 2609051 D 443906 CDS YP_001223051.1 148273490 5174163 2610519..2610689 1 NC_009480.1 hypothetical membrane protein (YP_062968.1| Hypothetical protein Lxx21740 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2610689 5174163 CMM_2306 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223051.1 2610519 D 443906 CDS YP_001223052.1 148273491 5173478 2610836..2612569 1 NC_009480.1 putative memebrane protein (YP_061591.1| Hypothetical protein Lxx05060 [Leifsonia xyli subsp. xyli str. CTCB07]; BAA19642.1| unnamed protein product [Actinobacillus actinomycetemcomitans]).; hypothetical protein 2612569 5173478 CMM_2307 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223052.1 2610836 D 443906 CDS YP_001223053.1 148273492 5175225 2612566..2613045 1 NC_009480.1 putative membrane protein, probably involved in polysaccharide biosynthesis (CAE11262.1| YngA protein [Bacillus amyloliquefaciens]; AAG49410.1| dTDP-glucose-4-keto-6-deoxy-D-glucose reductase [Actinobacillus actinomycetemcomitans]; ZP_00293833.1| COG2246: Predicted membrane protein [Thermobifida fusca]). pfam04138, GtrA,GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides.; Conserved hypothetical protein; hypothetical protein 2613045 5175225 CMM_2308 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223053.1 2612566 D 443906 CDS YP_001223054.1 148273493 5174997 complement(2612952..2613452) 1 NC_009480.1 conserved membrane protein (YP_061597.1| Hypothetical protein Lxx05130 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_788994.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Conserved hypothetical protein; hypothetical protein 2613452 5174997 CMM_2309 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223054.1 2612952 R 443906 CDS YP_001223055.1 148273494 5175845 complement(2613449..2614183) 1 NC_009480.1 putative glycosyl transferase (YP_061598.1| dolichyl-phosphate mannose synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787166.1| glycosyltransferase [Tropheryma whipplei str. Twist]; NP_835088.1| Glycosyltransferase involved in cell wall biogenesis [Bacillus cereus ATCC 14579]). pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. InterPro: Glycosyl transferase family 2. pfam00535,Glycos_transf_2, Glycosyl transferase. Diverse family,transferring sugar from UDP-glucose, UDP-N-acetyl-galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyl transferase 2614183 5175845 CMM_2310 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001223055.1 2613449 R 443906 CDS YP_001223056.1 148273495 5174842 complement(2615624..2616055) 1 NC_009480.1 putative molybdopterin cofactor biosynthesis protein (CAD47961.1| molybdopterin synthase (large subunit moaE) [Arthrobacter nicotinovorans]; CAF18780.1| MOLYBDOPTERIN SYNTHASE, LARGE SUBUNIT [Corynebacterium glutamicum ATCC 13032]). pfam02391, MoaE, MoaE protein. This family contains the MoaE protein that is involved in biosynthesis of molybdopterin. InterPro: Molydopterin converting factor subunit 2.; High confidence in function and specificity; molybdopterin cofactor biosynthesis protein 2616055 moaE 5174842 moaE Clavibacter michiganensis subsp. michiganensis NCPPB 382 molybdopterin cofactor biosynthesis protein YP_001223056.1 2615624 R 443906 CDS YP_001223057.1 148273496 5173919 complement(2616052..2616606) 1 NC_009480.1 putative molybdenum cofactor biosynthesis protein (NP_335315.1| molybdopterin biosynthesis Mog protein [Mycobacterium tuberculosis CDC1551]; NP_824847.1| putative molybdopterin biosynthesis protein [Streptomyces avermitilis MA-4680]). pfam00994, MoCF_biosynth, Probable molybdopterin binding domain. This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor.; Function unclear; putative molybdenum cofactor biosynthesis protein 2616606 moaB 5173919 moaB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdenum cofactor biosynthesis protein YP_001223057.1 2616052 R 443906 CDS YP_001223058.1 148273497 5174322 complement(2616603..2617097) 1 NC_009480.1 putative molybdenum cofactor biosynthesis protein (CAD47960.1| molybdopterin cofactor synthesis protein moaC [Arthrobacter nicotinovorans]; NP_599464.1| molybdenum cofactor biosynthesis enzyme [Corynebacterium glutamicum ATCC 13032]). pfam01967, MoaC, MoaC family. Members of this family are involved in molybdenum cofactor biosynthesis. However their molecular function is not known. InterPro: MoaC family.; High confidence in function and specificity; putative molybdenum cofactor biosynthesis protein 2617097 moaC 5174322 moaC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdenum cofactor biosynthesis protein YP_001223058.1 2616603 R 443906 CDS YP_001223059.1 148273498 5175520 complement(2617090..2618382) 1 NC_009480.1 putative molybdopterin biosynthesis protein (CAD47959.1| molybdopterin cofactor synthesis protein moeA [Arthrobacter nicotinovorans]; O53725|MEA2_MYCTU Molybdopterin biosynthesis protein moeA 2). pfam03453,MoeA_N, MoeA N-terminal region (domain I and II). pfam00994, MoCF_biosynth, Probable molybdopterin binding domain. pfam03454, MoeA_C, MoeA C-terminal region (domain IV). InterPro: Molybdenum cofactor biosynthesis protein.; High confidence in function and specificity; putative molybdopterin biosynthesis protein 2618382 moaA1 5175520 moaA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdopterin biosynthesis protein YP_001223059.1 2617090 R 443906 CDS YP_001223060.1 148273499 5175689 2618515..2618739 1 NC_009480.1 hypothetical protein 2618739 5175689 CMM_2315 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223060.1 2618515 D 443906 CDS YP_001223061.1 148273500 5173949 2618837..2619610 1 NC_009480.1 conserved hypothetical protein, putative carboxyphosphonoenolpyruvate phosphonomutase (AAU16741.1| conserved hypothetical protein; possible carboxyphosphonoenolpyruvate phosphonomutase [Bacillus cereus ZK]; NP_463608.1|; Function unclear; putative carboxyphosphonoenolpyruvate phosphonomutase 2619610 5173949 CMM_2316 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxyphosphonoenolpyruvate phosphonomutase YP_001223061.1 2618837 D 443906 CDS YP_001223062.1 148273501 5174993 2619720..2620640 1 NC_009480.1 putative methylthioadenosine phosphorylase (ZP_00059934.1| COG0005: Purine nucleoside phosphorylase [Clostridium thermocellum ATCC 27405]; NP_627402.1| putative methylthioadenosine phosphorylase [Streptomyces coelicolor A3(2)]). pfam00896, Mtap_PNP, Phosphorylase family 2.; Specificity unclear; putative methylthioadenosine phosphorylase 2620640 5174993 CMM_2317 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylthioadenosine phosphorylase YP_001223062.1 2619720 D 443906 CDS YP_001223063.1 148273502 5174589 2620637..2621701 1 NC_009480.1 putative UDP-glucose 4-epimerase (NP_627930.1| putative epimerase [Streptomyces coelicolor A3(2)]; NP_334969.1| NAD-dependent epimerase/dehydratase family protein [Mycobacterium tuberculosis CDC1551]). pfam01370,Epimerase, NAD dependent epimerase/dehydratase family. InterPro: NAD dependent epimerase/dehydratase family.; Specificity unclear; putative UDP-glucose 4-epimerase 2621701 galE3 5174589 galE3 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UDP-glucose 4-epimerase YP_001223063.1 2620637 D 443906 CDS YP_001223064.1 148273503 5174697 2621822..2622271 1 NC_009480.1 hypothetical protein 2622271 5174697 CMM_2319 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223064.1 2621822 D 443906 CDS YP_001223065.1 148273504 5174558 complement(2622330..2623118) 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (LVR_LEIAQ Levodione reductase ((6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase) [Leifsonia aquatica]; NP_691955.1| cyclohexanol dehydrogenase [Oceanobacillus iheyensis HTE831]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 2623118 5174558 CMM_2320 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001223065.1 2622330 R 443906 CDS YP_001223066.1 148273505 5174515 complement(2623196..2624224) 1 NC_009480.1 hypothetical membrane protein, putative protease (NP_691838.1| hypothetical protein OB0917 [Oceanobacillus iheyensis HTE831]; YP_099030.1| putative metal-dependent membrane protease [Bacteroides fragilis YCH46]).; hypothetical protein 2624224 5174515 CMM_2321 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223066.1 2623196 R 443906 CDS YP_001223067.1 148273506 5174888 complement(2624335..2624799) 1 NC_009480.1 hypothetical protein (ZP_00193445.2| hypothetical protein MBNC02003411 [Mesorhizobium sp. BNC1]; AAG02159.1| unknown [Zymomonas mobilis]).; hypothetical protein 2624799 5174888 CMM_2322 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223067.1 2624335 R 443906 CDS YP_001223068.1 148273507 5174111 complement(2624856..2625038) 1 NC_009480.1 hypothetical protein 2625038 5174111 CMM_2323 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223068.1 2624856 R 443906 CDS YP_001223069.1 148273508 5174377 2625536..2626249 1 NC_009480.1 hypothetical protein 2626249 5174377 CMM_2324 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223069.1 2625536 D 443906 CDS YP_001223070.1 148273509 5175603 2626246..2627307 1 NC_009480.1 hypothetical protein 2627307 5175603 CMM_2325 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223070.1 2626246 D 443906 CDS YP_001223071.1 148273510 5175147 2627593..2628633 1 NC_009480.1 putative permease (NP_721165.1| conserved hypothetical protein; putative permease [Streptococcus mutans UA159]; NP_978154.1| membrane protein, putative [Bacillus cereus ATCC 10987]; NP_825745.1| hypothetical protein SAV4568 [Streptomyces avermitilis MA-4680]). pfam03773, DUF318, Predicted permease. This family of integral membrane proteins are predicted to be permeases of unknown specificity.; putative permease 2628633 5175147 CMM_2326 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative permease YP_001223071.1 2627593 D 443906 CDS YP_001223072.1 148273511 5172996 2628620..2629543 1 NC_009480.1 conserved membrane protein (NP_681143.1| hypothetical protein tlr0353 [Thermosynechococcus elongatus BP-1]; ZP_00112177.1| COG3689: Predicted membrane protein [Nostoc punctiforme PCC 73102]). 2_A_01_02: Multidrug resistance protein; Conserved hypothetical protein; hypothetical protein 2629543 5172996 CMM_2327 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223072.1 2628620 D 443906 CDS YP_001223073.1 148273512 5173771 2629551..2630942 1 NC_009480.1 hypothetical protein 2630942 5173771 CMM_2328 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223073.1 2629551 D 443906 CDS YP_001223074.1 148273513 5173901 2630973..2631356 1 NC_009480.1 conserved hypothetical protein (ZP_00220356.1| COG0662: Mannose-6-phosphate isomerase [Burkholderia cepacia R1808]; ZP_00135743.1| COG0662: Mannose-6-phosphate isomerase [Pseudomonas aeruginosa UCBPP-PA14]).; Function unclear; hypothetical protein 2631356 5173901 CMM_2329 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223074.1 2630973 D 443906 CDS YP_001223075.1 148273514 5174188 complement(2631480..2632172) 1 NC_009480.1 hypothetical protein (NP_925435.1| hypothetical protein glr2489 [Gloeobacter violaceus PCC 7421]; ZP_00291340.1| COG2931: RTX toxins and related Ca2+-binding proteins).; hypothetical protein 2632172 5174188 CMM_2330 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223075.1 2631480 R 443906 CDS YP_001223076.1 148273515 5175166 2632438..2633121 1 NC_009480.1 putative transcriptional regulator, PadR family (NP_625650.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; NP_959288.1| hypothetical protein MAP0354c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam03551, PadR, Transcriptional regulator PadR-like family.; Specificity unclear; hypothetical protein 2633121 5175166 CMM_2331 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223076.1 2632438 D 443906 CDS YP_001223077.1 148273516 5173017 complement(2633198..2633452) 1 NC_009480.1 hypothetical protein 2633452 5173017 CMM_2332 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223077.1 2633198 R 443906 CDS YP_001223078.1 148273517 5173536 complement(2633569..2635188) 1 NC_009480.1 putative membrane-bound oxidoreductase (NP_624868.1| putative membrane-bound oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00228326.1| COG2041: Sulfite oxidase and related enzymes [Kineococcus radiotolerans SRS30216]). pfam00174, Oxidored_molyb,Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases. pfam03404, Mo-co_dimer, Mo-co oxidoreductase dimerisation domain. This domain is found in molybdopterin cofactor (Mo-co) oxidoreductases. It is involved in dimer formation, and has an Ig-fold structure.; Function unclear; putative membrane-bound oxidoreductase 2635188 5173536 CMM_2333 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound oxidoreductase YP_001223078.1 2633569 R 443906 CDS YP_001223079.1 148273518 5173655 complement(2635185..2636447) 1 NC_009480.1 putative two-component system sensor kinase (NP_825594.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; NP_824147.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2636447 5173655 CMM_2334 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001223079.1 2635185 R 443906 CDS YP_001223080.1 148273519 5173905 complement(2636444..2637295) 1 NC_009480.1 putative two-component system response regulator (NP_825593.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]; ZP_00062053.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Clostridium thermocellum ATCC 27405]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator 2637295 5173905 CMM_2335 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001223080.1 2636444 R 443906 CDS YP_001223081.1 148273520 5173814 2637444..2638151 1 NC_009480.1 putative glycosyl transferase (NP_627933.1| putative glycosyltransferase [Streptomyces coelicolor A3(2)]; O32851|Y539_MYCTU Putative glycosyl transferase Rv0539/MT0564/Mb0553). pfam00535, Glycos_transf_2,Glycosyl transferase. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.; Function unclear; putative glycosyltransferase 2638151 5173814 CMM_2336 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyltransferase YP_001223081.1 2637444 D 443906 CDS YP_001223082.1 148273521 5175757 2638148..2638831 1 NC_009480.1 conserved hypothetical protein (NP_825749.1| hypothetical protein SAV4572 [Streptomyces avermitilis MA-4680]; NP_215054.1| hypothetical protein Rv0540 [Mycobacterium tuberculosis H37Rv]). pfam05143, DUF703,Uncharacterized BCR (DUF703). Proteins in this family have no known function. They contain many conserved aspartates that might suggest this is a metalloprotein.; Function unclear; hypothetical protein 2638831 5175757 CMM_2337 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223082.1 2638148 D 443906 CDS YP_001223083.1 148273522 5175196 2638828..2639529 1 NC_009480.1 putative SAM-dependant methyltransferase (NP_825748.1| hypothetical protein [Streptomyces avermitilis MA-4680]; AAK68925.1| putative methyltransferase [Bacteroides fragilis]). InterPro: SAM (and some other nucleotide) binding motif.; Family membership; putative SAM-dependant methyltransferase 2639529 5175196 CMM_2338 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative SAM-dependant methyltransferase YP_001223083.1 2638828 D 443906 CDS YP_001223084.1 148273523 5174773 complement(2639478..2639957) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2639957 5174773 CMM_2339 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223084.1 2639478 R 443906 CDS YP_001223085.1 148273524 5173492 complement(2639957..2641198) 1 NC_009480.1 conserved membrane protein (CAB07013.1| PROBABLE CONSERVED TRANSMEMBRANE PROTEIN [Mycobacterium tuberculosis H37Rv]; NP_627937.1| putative membrane protein [Streptomyces coelicolor A3(2)]). pfam00174,Oxidored_molyb, Oxidoreductase molybdopterin binding domain. CynX: Cyanate transport system protein; Family membership; hypothetical protein 2641198 5173492 CMM_2340 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223085.1 2639957 R 443906 CDS YP_001223086.1 148273525 5173790 2641277..2642725 1 NC_009480.1 hypothetical membrane protein (only weak similarities: NP_960846.1| hypothetical protein MAP1912 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_056579.1| conserved membrane protein [Propionibacterium acnes KPA171202]).; hypothetical protein 2642725 5173790 CMM_2341 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223086.1 2641277 D 443906 CDS YP_001223087.1 148273526 5175391 complement(2642726..2643784) 1 NC_009480.1 putative molybdate ABC transporter, ATP-binding protein (NP_822897.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00292621.1| COG1118: ABC-type sulfate/molybdate transport systems, ATPase component [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putative molybdate ABC transporter, ATP-binding protein 2643784 modC 5175391 modC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdate ABC transporter, ATP-binding protein YP_001223087.1 2642726 R 443906 CDS YP_001223088.1 148273527 5173899 complement(2643781..2644638) 1 NC_009480.1 putative molybdate ABC transporter, permease component (NP_627897.1| putative ABC transporter membrane subunit [Streptomyces coelicolor A3(2)]; ZP_00292622.1| COG4149: ABC-type molybdate transport system, permease component [Thermobifida fusca]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; putative molybdate ABC transporter, permease component 2644638 modB 5173899 modB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdate ABC transporter, permease component YP_001223088.1 2643781 R 443906 CDS YP_001223089.1 148273528 5174846 complement(2644628..2645434) 1 NC_009480.1 putative molybdate ABC transporter, substrate-binding protein (NP_822895.1| putative substrate-binding periplasmic transport [Streptomyces avermitilis MA-4680]; YP_120541.1| putative transporter [Nocardia farcinica]).; High confidence in function and specificity; putative molybdate ABC transporter, substrate-binding protein 2645434 modA 5174846 modA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdate ABC transporter, substrate-binding protein YP_001223089.1 2644628 R 443906 CDS YP_001223090.1 148273529 5175807 complement(2645434..2645946) 1 NC_009480.1 putative transcriptional regulator involved in molybdate uptake (NP_960055.1| hypothetical protein MAP1121c [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_055214.1| putative molybdopterin-binding protein [Propionibacterium acnes KPA171202]). COG3585, MopI,Molybdopterin-binding protein [Coenzyme metabolism].; High confidence in function and specificity; putative transcriptional regulator involved in molybdate uptake 2645946 5175807 CMM_2345 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator involved in molybdate uptake YP_001223090.1 2645434 R 443906 CDS YP_001223091.1 148273530 5174673 2646067..2647125 1 NC_009480.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 2647125 moaA 5174673 moaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 molybdenum cofactor biosynthesis protein A YP_001223091.1 2646067 D 443906 CDS YP_001223092.1 148273531 5175923 2647139..2647393 1 NC_009480.1 putative molybdopterin converting factor, small subunit (CAD47957.1| putative molybdopterin cofactor synthesis protein moaD [Arthrobacter nicotinovorans]; NP_959740.1| MoaD2 [Mycobacterium avium subsp. paratuberculosis str. k10]).; High confidence in function and specificity; putative molybdopterin converting factor 2647393 moaD 5175923 moaD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdopterin converting factor YP_001223092.1 2647139 D 443906 CDS YP_001223093.1 148273532 5173724 2647417..2648304 1 NC_009480.1 putative siderophore-interacting protein (NP_600036.1| siderophore- interacting protein [Corynebacterium glutamicum ATCC 13032]; ZP_00139712.1| COG2375: Siderophore-interacting protein [Pseudomonas aeruginosa UCBPP-PA14]). pfam04954, SIP, Siderophore-interacting protein.; Function unclear; putative siderophore-interacting protein 2648304 5173724 CMM_2348 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative siderophore-interacting protein YP_001223093.1 2647417 D 443906 CDS YP_001223094.1 148273533 5174685 2648374..2649348 1 NC_009480.1 putative Fe3+-siderophore ABC transporter,substrate-binding protein (NP_600037.1| ABC-type cobalamin/Fe3+-siderophore transport system, periplasmic component [Corynebacterium glutamicum ATCC 13032]; ZP_00187377.2| COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component [Rubrobacter xylanophilus DSM 9941]). , pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport.; Specificity unclear; putative Fe3+-siderophore ABC transporter,substrate-binding protein 2649348 fecB1 5174685 fecB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,substrate-binding protein YP_001223094.1 2648374 D 443906 CDS YP_001223095.1 148273534 5172986 2649345..2650358 1 NC_009480.1 putative Fe3+-siderophore ABC transporter, permease component (CAF19214.1| cobalamin/ Fe3+-siderophores transport system, permease component [Corynebacterium glutamicum ATCC 13032]; AAD29085.1| FepD [Yersinia enterocolitica]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system. InterPro: FecCD transport family.; Specificity unclear; putative Fe3+-siderophore ABC transporter,permease component 2650358 fecC1 5172986 fecC1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,permease component YP_001223095.1 2649345 D 443906 CDS YP_001223096.1 148273535 5173027 2650355..2651407 1 NC_009480.1 putative Fe3+-siderophore ABC transporter, permease component (NP_535687.1| ABC transporter, membrane spanning protein [iron] [Agrobacterium tumefaciens str. C58]; CAF19213.1| cobalamin/Fe3+-siderophores transport system,permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.,InterPro: FecCD transport family; Specificity unclear; putative Fe3+-siderophore ABC transporter,permease component 2651407 fecD1 5173027 fecD1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Fe3+-siderophore ABC transporter,permease component YP_001223096.1 2650355 D 443906 CDS YP_001223097.1 148273536 5173137 complement(2651453..2651932) 1 NC_009480.1 conserved hypothetical protein (ZP_00028735.1| COG3865: Uncharacterized protein conserved in bacteria [Burkholderia fungorum]; NP_961602.1| hypothetical protein MAP2668c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam06983, 3-dmu-9_3-mt, 3-demethylubiquinone-9 3-methyltransferase.; Function unclear; hypothetical protein 2651932 5173137 CMM_2352 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223097.1 2651453 R 443906 CDS YP_001223098.1 148273537 5174753 complement(2652042..2653007) 1 NC_009480.1 putative membrane protein (NP_628002.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 2653007 5174753 CMM_2353 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223098.1 2652042 R 443906 CDS YP_001223099.1 148273538 5175235 complement(2653004..2653354) 1 NC_009480.1 putative transcriptional regulator, GntR family (NP_628001.1| putative putative transcriptional regulator,GntR family [Streptomyces coelicolor A3(2)]; NP_765180.1| transcription regulator GntR family [Staphylococcus epidermidis ATCC 12228]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator 2653354 5175235 CMM_2354 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001223099.1 2653004 R 443906 CDS YP_001223100.1 148273539 5174314 complement(2653401..2654468) 1 NC_009480.1 putative transcriptional regulator, LacI family (ZP_00238821.1| ribose operon repressor RbsR [Bacillus cereus G9241]; NP_621898.1| Transcriptional regulator [Thermoanaerobacter tengcongensis]; NP_625360.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. This family includes the periplasmic binding proteins, and the LacI family transcriptional regulators. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator 2654468 5174314 CMM_2355 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001223100.1 2653401 R 443906 CDS YP_001223101.1 148273540 5175579 complement(2654447..2656480) 1 NC_009480.1 putative oxidoreductase (NP_106951.1| ; NP_533647.1| oxidoreductase [Agrobacterium tumefaciens str. C58]). contains two domains: N-terminal, COG0673,MviM, Predicted dehydrogenases and related proteins; pfam01408, GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. C-terminal, COG0667, Tas, Predicted oxidoreductases; pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 2656480 5175579 CMM_2356 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223101.1 2654447 R 443906 CDS YP_001223102.1 148273541 5174159 complement(2656608..2656919) 1 NC_009480.1 putative transcriptional regulator,ArsR family (NP_422181.1| conserved hypothetical protein [Caulobacter crescentus CB15]; ZP_00199062.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01022, HTH_5, Bacterial regulatory protein, arsR family.; Specificity unclear; ArsR family transcriptional regulator 2656919 5174159 CMM_2357 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ArsR family transcriptional regulator YP_001223102.1 2656608 R 443906 CDS YP_001223103.1 148273542 5174432 complement(2656919..2657335) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2657335 5174432 CMM_2358 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223103.1 2656919 R 443906 CDS YP_001223104.1 148273543 5174262 complement(2657452..2657946) 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_629432.1| putative MarR-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00197677.1| COG1846: Transcriptional regulators [Mesorhizobium sp. BNC1]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein 2657946 5174262 CMM_2359 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223104.1 2657452 R 443906 CDS YP_001223105.1 148273544 5175594 2658055..2658552 1 NC_009480.1 conserved membrane protein (NP_739226.1| hypothetical protein CE2616 [Corynebacterium efficiens YS-314]; YP_061908.1| Hypothetical protein Lxx09140 [Leifsonia xyli subsp. xyli str. CTCB07]). 2_A_01_02: Multidrug resistance protein; Conserved hypothetical protein; hypothetical protein 2658552 5175594 CMM_2360 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223105.1 2658055 D 443906 CDS YP_001223106.1 148273545 5174415 complement(2658605..2659216) 1 NC_009480.1 hypothetical acetyltransferase (ZP_00210091.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Magnetospirillum magnetotacticum MS-1]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Hypothetical protein; acetyltransferase 2659216 5174415 CMM_2361 Clavibacter michiganensis subsp. michiganensis NCPPB 382 acetyltransferase YP_001223106.1 2658605 R 443906 CDS YP_001223107.1 148273546 5175545 2659384..2660649 1 NC_009480.1 hypothetical protein 2660649 5175545 CMM_2362 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223107.1 2659384 D 443906 CDS YP_001223108.1 148273548 5175076 complement(2660677..2661864) 1 NC_009480.1 putative molybdenum cofactor biosynthesis protein (Molybdopterin synthase sulfurylase) (YP_120782.1| putative molybdopterin biosynthesis protein [Nocardia farcinica]; NP_301623.1| probably involved in molybdopterin biosynthesis [Mycobacterium leprae TN]). pfam00899, ThiF, ThiF family. This family contains a repeated domain in ubiquitin activating enzyme E1 and members of the bacterial ThiF/MoeB/HesA family. pfam05237,MoeZ_MoeB, MoeZ/MoeB domain. pfam00581, Rhodanese,Rhodanese-like domain.; High confidence in function and specificity; putative molybdenum cofactor biosynthesis protein 2661864 moeB 5175076 moeB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative molybdenum cofactor biosynthesis protein YP_001223108.1 2660677 R 443906 CDS YP_001223109.1 148273547 5174826 2661863..2663569 1 NC_009480.1 conserved membrane protein (NP_962739.1| hypothetical protein MAP3805c [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_826266.1| hypothetical protein SAV5089 [Streptomyces avermitilis MA-4680]). 2A0106: citrate-proton symport; Conserved hypothetical protein; hypothetical protein 2663569 5174826 CMM_2364 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223109.1 2661863 D 443906 CDS YP_001223110.1 148273549 5174185 complement(2663582..2664442) 1 NC_009480.1 putative hydrolase (NP_823898.1| putative hydrolase [Streptomyces avermitilis MA-4680]; ZP_00216890.1| COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [Burkholderia cepacia R18194]). pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Family membership; putative hydrolase 2664442 5174185 CMM_2365 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001223110.1 2663582 R 443906 CDS YP_001223111.1 148273550 5174593 2664529..2665032 1 NC_009480.1 conserved hypothetical protein (NP_624780.1| hypothetical protein SCF51A.38 [Streptomyces coelicolor A3(2)]; YP_120059.1| hypothetical protein nfa38470 [Nocardia farcinica]). pfam07336, DUF1470, Protein of unknown function (DUF1470). ahpD_dom: alkylhydroperoxidase AhpD famil; hypothetical protein 2665032 5174593 CMM_2366 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223111.1 2664529 D 443906 CDS YP_001223112.1 148273551 5175414 complement(2666044..2666982) 1 NC_009480.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2666982 ispE 5175414 ispE Clavibacter michiganensis subsp. michiganensis NCPPB 382 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_001223112.1 2666044 R 443906 CDS YP_001223113.1 148273552 5174936 complement(2666993..2667907) 1 NC_009480.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 2667907 ksgA 5174936 ksgA Clavibacter michiganensis subsp. michiganensis NCPPB 382 dimethyladenosine transferase YP_001223113.1 2666993 R 443906 CDS YP_001223114.1 148273553 5175663 complement(2667904..2668854) 1 NC_009480.1 putative DNase (YP_062611.1| sec-independent protein TadD [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227356.1| COG0084: Mg-dependent DNase [Kineococcus radiotolerans SRS30216]; NP_789377.1| putative TatD-family DNase [Tropheryma whipplei TW08/27]). pfam01026,TatD_DNase, TatD related DNase. This family of proteins are related to a large superfamily of metalloenzymes. TatD, a member of this family has been shown experimentally to be a DNase enzyme.; Function unclear; hypothetical protein 2668854 5175663 CMM_2369 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223114.1 2667904 R 443906 CDS YP_001223115.1 148273554 5175693 complement(2668926..2670503) 1 NC_009480.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2670503 metS 5175693 metS Clavibacter michiganensis subsp. michiganensis NCPPB 382 methionyl-tRNA synthetase YP_001223115.1 2668926 R 443906 CDS YP_001223116.1 148273555 5174656 complement(2670566..2671717) 1 NC_009480.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 2671717 gltA1 5174656 gltA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 citrate synthase YP_001223116.1 2670566 R 443906 CDS YP_001223117.1 148273556 5175234 2671965..2673452 1 NC_009480.1 putative dihydrolipoamide dehydrogenase (E3) component (ZP_00163991.2| COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Synechococcus elongatus PCC 7942]; NP_713067.1| Dihydrolipoamide dehydrogenase [Leptospira interrogans serovar Lai str. 56601]). ,pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. , pfam02852, Pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.; Function unclear; putative dihydrolipoamide dehydrogenase (E3) component 2673452 5175234 CMM_2372 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dihydrolipoamide dehydrogenase (E3) component YP_001223117.1 2671965 D 443906 CDS YP_001223118.1 148273557 5175948 2673487..2674095 1 NC_009480.1 putative NAD(P)H oxidoreductase (NP_249916.1| probable NAD(P)H dehydrogenase [Pseudomonas aeruginosa PA01]; ZP_00270658.1| COG2249: Putative NADPH-quinone reductase (modulator of drug activity B) [Rhodospirillum rubrum])., , pfam02525, Flavodoxin_2, Flavodoxin-like fold.; Function unclear; putative NAD(P)H oxidoreductase 2674095 5175948 CMM_2373 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NAD(P)H oxidoreductase YP_001223118.1 2673487 D 443906 CDS YP_001223119.1 148273558 5175444 complement(2674118..2675161) 1 NC_009480.1 putative Zn-dependant alcohol dehydrogenase (NP_628443.1| putative NADP-dependent alcohol dehydrogenase [Streptomyces coelicolor A3(2)]; NP_299023.1| NADP-alcohol dehydrogenase [Xylella fastidiosa 9a5c]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. tdh: L-threonine 3-dehydrogenase; Function unclear; putative Zn-dependant alcohol dehydrogenase 2675161 5175444 CMM_2374 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant alcohol dehydrogenase YP_001223119.1 2674118 R 443906 CDS YP_001223120.1 148273559 5175433 2675207..2675797 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00191751.2| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_628442.1| putative transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator 2675797 5175433 CMM_2375 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223120.1 2675207 D 443906 CDS YP_001223121.1 148273560 5174989 complement(2675821..2676240) 1 NC_009480.1 putative membrane protein (AAN58622.1| conserved hypothetical protein [Streptococcus mutans UA159]; AAF24085.1| unknown [Staphylococcus aureus]).; hypothetical protein 2676240 5174989 CMM_2376 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223121.1 2675821 R 443906 CDS YP_001223122.1 148273561 5172973 2676441..2677838 1 NC_009480.1 putative SAM-dependent methyltransferase (NP_630088.1| hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00060190.1| COG0500: SAM-dependent methyltransferases [Clostridium thermocellum ATCC 27405]).; Function unclear; putative SAM-dependent methyltransferase 2677838 5172973 CMM_2377 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative SAM-dependent methyltransferase YP_001223122.1 2676441 D 443906 CDS YP_001223123.1 148273562 5173521 2677835..2680420 1 NC_009480.1 putative phosphatase (ZP_00227056.1| COG0639: Diadenosine tetraphosphatase and related serine/threonine protein phosphatases [Kineococcus radiotolerans SRS30216]; NP_630089.1| putative phosphatase [Streptomyces coelicolor A3(2)]). pfam00149, Metallophos,Calcineurin-like phosphoesterase. InterPro: Serine/threonine specific protein phosphatase.; Function unclear; putative phosphatase 2680420 5173521 CMM_2378 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001223123.1 2677835 D 443906 CDS YP_001223124.1 148273563 5174785 complement(2680639..2681553) 1 NC_009480.1 putative methylisocitrate lyase (YP_061313.1| phosphonomutase [Leifsonia xyli subsp. xyli str. CTCB07]; Q8NSL2|PRB2_CORGL Probable methylisocitrate lyase 2 (2-methylisocitrate lyase 2)).; Specificity unclear; putative methylisocitrate lyase/phosphonomutase 2681553 prpB 5174785 prpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylisocitrate lyase/phosphonomutase YP_001223124.1 2680639 R 443906 CDS YP_001223125.1 148273564 5174213 complement(2681553..2683103) 1 NC_009480.1 putative 2-methylcitrate dehydratase (ZP_00267780.1| COG2079: Uncharacterized protein involved in propionate catabolism [Rhodospirillum rubrum]; Q8NSL3|PRD2_CORGL 2-methylcitrate dehydratase 2). pfam03972, MmgE_PrpD, MmgE/PrpD family. This family includes 2-methylcitrate dehydratase EC:4.2.1.79 that is required for propionate catabolism. It catalyses the third step of the 2-methylcitric acid cycle.; Specificity unclear; putative 2-methylcitrate dehydratase 2683103 prpD 5174213 prpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2-methylcitrate dehydratase YP_001223125.1 2681553 R 443906 CDS YP_001223126.1 148273565 5174953 2683142..2684110 1 NC_009480.1 putative acetyltransferase pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (duplicated). similarities N-terminal: putative IAA acetyltransferase; D97569 iaa acetyltransferase [imported] - Agrobacterium tumefaciens (strain C58,Cereon); P26945|IAAT_AZOBR IAA ACETYLTRANSFERASE). C-terminal: NP_627571.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; ZP_00215080.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Burkholderia cepacia R18194]. duplicated domain: pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative duplicated acetyltransferase 2684110 5174953 CMM_2381 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative duplicated acetyltransferase YP_001223126.1 2683142 D 443906 CDS YP_001223127.1 148273566 5175248 2685035..2686447 1 NC_009480.1 hypothetical protein, putative perforin (CAE13708.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1]; ZP_00328149.1| hypothetical protein Tery02000057 [Trichodesmium erythraeum IMS101]). , weak similarity to: smart00457,MACPF, membrane-attack complex/perforin; putative perforin 2686447 5175248 CMM_2382 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative perforin YP_001223127.1 2685035 D 443906 CDS YP_001223128.1 148273567 5173203 complement(2686864..2687451) 1 NC_009480.1 conserved hypothetical protein (NP_642470.1| hypothetical protein XAC2153 [Xanthomonas axonopodis pv. citri str. 306]; ZP_00127398.2| COG3506: Uncharacterized conserved protein [Pseudomonas syringae pv. syringae B728a]). pfam07081, DUF1349, Protein of unknown function (DUF1349).; hypothetical protein 2687451 5173203 CMM_2383 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223128.1 2686864 R 443906 CDS YP_001223129.1 148273568 5173430 2687476..2688069 1 NC_009480.1 putative sugar acetyltransferase (NP_631564.1| putative sugar acetyltransferase [Streptomyces coelicolor A3(2)]; ZP_00291641.1| COG0110: Acetyltransferase (isoleucine patch superfamily) [Thermobifida fusca]). cd00208, LbetaH, Left-Handed Parallel beta-Helix; Proteins containing hexapeptide repeats are often enzymes showing acyl-transferase activity, many are trimeric in their active form. InterPro: Bacterial transferase hexapeptide repeat.; Function unclear; putative sugar acetyltransferase 2688069 5173430 CMM_2384 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar acetyltransferase YP_001223129.1 2687476 D 443906 CDS YP_001223130.1 148273569 5175709 2688066..2688659 1 NC_009480.1 putative transcriptional regulator, TetR family (NP_631563.1| putative tetR-family transcriptional regulatory protein [Streptomyces coelicolor A3(2)]; NP_415367.1| putative DEOR-type transcriptional regulator; putative transcriptional regulator (TetR family) [Escherichia coli K12]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator 2688659 5175709 CMM_2385 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223130.1 2688066 D 443906 CDS YP_001223131.1 148273570 5175357 2688928..2690457 1 NC_009480.1 putative membrane-bound tyrosin-protein phosphatase (YP_014420.1| protein-tyrosine phosphatase, putative [Listeria monocytogenes str. 4b F2365]). pfam03162,Y_phosphatase2, Tyrosine phosphatase family. InterPro: Tyrosine specific protein phosphatase and dual specificity protein phosphatase family.; Family membership; putative membrane-bound tyrosin-protein phosphatase 2690457 5175357 CMM_2386 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound tyrosin-protein phosphatase YP_001223131.1 2688928 D 443906 CDS YP_001223132.1 148273571 5175041 2690466..2691113 1 NC_009480.1 Hypothetical protein; hypothetical protein 2691113 5175041 CMM_2387 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223132.1 2690466 D 443906 CDS YP_001223133.1 148273572 5175108 2691192..2692289 1 NC_009480.1 conserved membrane protein (NP_736677.1| hypothetical protein CE0067 [Corynebacterium efficiens YS-314]; NP_625097.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]).; Conserved hypothetical protein; hypothetical protein 2692289 5175108 CMM_2388 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223133.1 2691192 D 443906 CDS YP_001223134.1 148273573 5174945 complement(2692308..2693273) 1 NC_009480.1 putative permease, DMT family (ZP_00294424.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Thermobifida fusca]; YP_117052.1| hypothetical protein nfa8430 [Nocardia farcinica]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (duplicated).; Specificity unclear; permease DMT family 2693273 5174945 CMM_2389 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease DMT family YP_001223134.1 2692308 R 443906 CDS YP_001223135.1 148273574 5174453 2693347..2693907 1 NC_009480.1 conserved hypothetical protein (NP_827985.1| hypothetical protein SAV6809 [Streptomyces avermitilis MA-4680]; NP_927352.1| hypothetical protein glr4405 [Gloeobacter violaceus PCC 7421]). pfam07336, DUF1470,Protein of unknown function (DUF1470).; hypothetical protein 2693907 5174453 CMM_2390 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223135.1 2693347 D 443906 CDS YP_001223136.1 148273575 5173313 complement(2693927..2694742) 1 NC_009480.1 putative methyltransferase (YP_062614.1| tetrapyrrole methylase [Leifsonia xyli subsp. xyli str. CTCB07]; BAB98284.1| Predicted methyltransferases [Corynebacterium glutamicum ATCC 13032]). pfam00590,TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases. This family uses S-AdoMet in the methylation of diverse substrates. InterPro: Uncharacterized protein family UPF0011.; Function unclear; putative methyltransferase 2694742 5173313 CMM_2391 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001223136.1 2693927 R 443906 CDS YP_001223137.1 148273576 5173247 complement(2694739..2695059) 1 NC_009480.1 hypothetical protein 2695059 5173247 CMM_2392 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223137.1 2694739 R 443906 CDS YP_001223138.1 148273577 5173215 2695639..2696082 1 NC_009480.1 conserved membrane protein (NP_939230.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]; NP_744462.1| hypothetical protein PP2313 [Pseudomonas putida KT2440]). pfam04173, DoxD, DoxD-like family.; Conserved hypothetical protein; hypothetical protein 2696082 5173215 CMM_2393 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223138.1 2695639 D 443906 CDS YP_001223139.1 148273578 5174772 complement(2696095..2696316) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2696316 5174772 CMM_2394 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223139.1 2696095 R 443906 CDS YP_001223140.1 148273579 5173518 2696499..2698745 1 NC_009480.1 putative alpha glycosidase 2698745 aglB 5173518 aglB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha glycosidase YP_001223140.1 2696499 D 443906 CDS YP_001223141.1 148273580 5175551 complement(2698798..2699334) 1 NC_009480.1 hypothetical protein 2699334 5175551 CMM_2396 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223141.1 2698798 R 443906 CDS YP_001223142.1 148273581 5174550 complement(2699336..2699902) 1 NC_009480.1 hypothetical protein 2699902 5174550 CMM_2397 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223142.1 2699336 R 443906 CDS YP_001223143.1 148273582 5174378 2700125..2701852 1 NC_009480.1 putative dolichyl-phosphate-mannose-protein mannosyltransferase (YP_062615.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228125.1| COG1928: Dolichyl-phosphate-mannose-protein O-mannosyl transferase [Kineococcus radiotolerans SRS30216]; NP_627370.1| putative integral membrane protein. [Streptomyces coelicolor A3(2)]). pfam02366, PMT,Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyl- transferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyse the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. InterPro: Dolichyl-phosphate-mannose-protein mannosyltransferase.; Function unclear; putative dolichyl-phosphate-mannose-protein mannosyltransferase 2701852 5174378 CMM_2398 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dolichyl-phosphate-mannose-protein mannosyltransferase YP_001223143.1 2700125 D 443906 CDS YP_001223144.1 148273583 5173464 2701852..2702856 1 NC_009480.1 conserved membrane protein (CAF18580.1| HYPOTHETICAL MEMBRANE PROTEIN [Corynebacterium glutamicum ATCC 13032]; ZP_00226109.1| COG2855: Predicted membrane protein [Kineococcus radiotolerans SRS30216]). pfam03601,Cons_hypoth698, Conserved hypothetical protein 698.; hypothetical protein 2702856 5173464 CMM_2399 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223144.1 2701852 D 443906 CDS YP_001223145.1 148273584 5175392 2702957..2704252 1 NC_009480.1 putative O-acetylhomoserine (thiol)-lyase (ZP_00352381.1| COG2873: O-acetylhomoserine sulfhydrylase [Kineococcus radiotolerans SRS30216]; ZP_00329508.1| COG2873: O-acetylhomoserine sulfhydrylase [Moorella thermoacetica ATCC 39073]). pfam01053, Cys_Met_Meta_PP,Cys/Met metabolism PLP-dependent enzyme. This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.; High confidence in function and specificity; putative O-acetylhomoserine (thiol)-lyase 2704252 5175392 CMM_2400 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative O-acetylhomoserine (thiol)-lyase YP_001223145.1 2702957 D 443906 CDS YP_001223146.1 148273585 5172962 2704249..2705022 1 NC_009480.1 conserved hypothetical protein (ZP_00225776.1| COG1832: Predicted CoA-binding protein [Kineococcus radiotolerans SRS30216]; NP_243007.1| BH2141 unknown conserved protein [Bacillus halodurans C-125]). pfam02629,CoA_binding, CoA binding domain. This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases. InterPro: DUF184.; Family membership; hypothetical protein 2705022 5172962 CMM_2401 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223146.1 2704249 D 443906 CDS YP_001223147.1 148273586 5175622 complement(2705041..2705550) 1 NC_009480.1 conserved hypothetical protein (NP_683235.1| hypothetical protein tll2445 [Thermosynechococcus elongatus BP-1]; ZP_00353314.1| COG2343: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). pfam04248, DUF427, Domain of unknown function (DUF427). L37a: ribosomal protein L37a; hypothetical protein 2705550 5175622 CMM_2402 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223147.1 2705041 R 443906 CDS YP_001223148.1 148273587 5172922 2705737..2705997 1 NC_009480.1 conserved membrane protein (YP_056449.1| hypothetical protein PPA1762 [Propionibacterium acnes KPA171202]; ZP_00208942.1| COG2261: Predicted membrane protein [Magnetospirillum magnetotacticum MS-1]).; Conserved hypothetical protein; hypothetical protein 2705997 5172922 CMM_2403 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223148.1 2705737 D 443906 CDS YP_001223149.1 148273588 5174897 2706088..2706834 1 NC_009480.1 Hypothetical protein; hypothetical protein 2706834 5174897 CMM_2404 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223149.1 2706088 D 443906 CDS YP_001223150.1 148273589 5174543 2706844..2708211 1 NC_009480.1 putative L-serine dehydratase (ZP_00278039.1| COG1760: L-serine deaminase [Burkholderia fungorum LB400]; ZP_00244926.1| COG1760: L-serine deaminase [Rubrivivax gelatinosus PM1]). pfam03313, SDH_alpha,Serine dehydratase alpha chain.L-serine dehydratase (EC:4.2.1.13) is a found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate. This enzyme is part of the gluconeogenesis pathway. pfam03315, SDH_beta, Serine dehydratase beta chain. InterPro: Iron-sulfur-dependent L-serine dehydratase single chain form.; High confidence in function and specificity; putative L-serine dehydratase 2708211 sdaA 5174543 sdaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-serine dehydratase YP_001223150.1 2706844 D 443906 CDS YP_001223151.1 148273590 5175647 2708249..2708644 1 NC_009480.1 hypothetical membrane protein (NP_600018.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032];).; Hypothetical protein; hypothetical protein 2708644 5175647 CMM_2406 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223151.1 2708249 D 443906 CDS YP_001223152.1 148273591 5173090 complement(2708641..2709747) 1 NC_009480.1 conserved hypothetical protein (AAL17938.1| alanine-rich hypothetical protein [Mycobacterium smegmatis]; NP_626160.1| hypothetical alanine-rich protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 2709747 5173090 CMM_2407 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223152.1 2708641 R 443906 CDS YP_001223153.1 148273592 5174000 complement(2709744..2710535) 1 NC_009480.1 putative transcriptional regulator, IclR family (NP_827564.1| putative IclR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_626139.1| putative IclR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). , pfam01614,IclR, Bacterial transcriptional regulator. , InterPro: Bacterial regulatory proteins IclR family.; Specificity unclear; IclR family transcriptional regulator 2710535 5174000 CMM_2408 Clavibacter michiganensis subsp. michiganensis NCPPB 382 IclR family transcriptional regulator YP_001223153.1 2709744 R 443906 CDS YP_001223154.1 148273593 5173934 complement(2710532..2711326) 1 NC_009480.1 putative NDP-sugar epimerase (AAL17942.1| putative UDP glucose epimerase [Mycobacterium smegmatis]; ZP_00057790.1| COG0451: Nucleoside-diphosphate-sugar epimerases [Thermobifida fusca]). pfam01370, Epimerase,NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions.; Function unclear; putative NDP-sugar epimerase 2711326 5173934 CMM_2409 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NDP-sugar epimerase YP_001223154.1 2710532 R 443906 CDS YP_001223155.1 148273594 5173376 2711440..2712786 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (YP_069044.1| putative sugar binding protein, ABC transport system [Yersinia pseudotuberculosis IP 32953]; NP_826308.1| putative sugar transporter sugar-binding protein [Streptomyces avermitilis MA-4680]). pfam01547,SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 2712786 5173376 CMM_2410 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001223155.1 2711440 D 443906 CDS YP_001223156.1 148273595 5175957 2712783..2713745 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_406930.1| sugar transport system, permease protein [Yersinia pestis CO92]; NP_107401.1| ABC transporter,permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 2713745 5175957 CMM_2411 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223156.1 2712783 D 443906 CDS YP_001223157.1 148273596 5173983 2713742..2714647 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_406929.1| sugar transport system, permease protein [Yersinia pestis CO92]; YP_059565.1| N-acetylneuraminate transport system permease protein [Streptococcus pyogenes MGAS10394]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 2714647 5173983 CMM_2412 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223157.1 2713742 D 443906 CDS YP_001223158.1 148273597 5174823 2714652..2715884 1 NC_009480.1 putative glucarate dehydratase (EAA73209.1| conserved hypothetical protein [Gibberella zeae PH-1]; NP_826758.1| putative glucarate dehydratase [Streptomyces avermitilis MA-4680]). pfam02746, MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain. pfam01188, MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain. InterPro: Mandelate racemase/muconate lactonizing enzyme family.; Specificity unclear; putative glucarate dehydratase 2715884 5174823 CMM_2413 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glucarate dehydratase YP_001223158.1 2714652 D 443906 CDS YP_001223159.1 148273598 5173305 2715884..2716852 1 NC_009480.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 2716852 5173305 CMM_2414 Clavibacter michiganensis subsp. michiganensis NCPPB 382 5-dehydro-4-deoxyglucarate dehydratase YP_001223159.1 2715884 D 443906 CDS YP_001223160.1 148273599 5175779 complement(2716857..2718758) 1 NC_009480.1 conserved hypothetical protein (ZP_00291796.1| COG1331: Highly conserved protein containing a thioredoxin domain [Thermobifida fusca]; NP_824472.1| hypothetical protein SAV3296 [Streptomyces avermitilis MA-4680]). pfam03190, DUF255, Protein of unknown function, DUF255.; hypothetical protein 2718758 5175779 CMM_2415 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223160.1 2716857 R 443906 CDS YP_001223161.1 148273600 5174308 complement(2718810..2719976) 1 NC_009480.1 putative magnesium and cobalt transport protein,MIT family (NP_823212.1| putative metal-transport protein [Streptomyces avermitilis MA-4680]; ZP_00292887.1| COG0598: Mg2+ and Co2+ transporters [Thermobifida fusca]). pfam01544, CorA, CorA-like Mg2+ transporter protein. ,InterPro: CorA-like Mg2+ transporter protein.; Specificity unclear; Mg2+/Co2+ transporter 2719976 corA2 5174308 corA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Mg2+/Co2+ transporter YP_001223161.1 2718810 R 443906 CDS YP_001223162.1 148273601 5173781 complement(2720024..2720866) 1 NC_009480.1 putative aldo/keto reductase (BAB99752.1| Aldo/keto reductases, related to diketogulonate reductase [Corynebacterium glutamicum ATCC 13032]; NP_788971.1| 2,5-diketo-D-gluconic acid reductase A [Tropheryma whipplei TW08/27]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative aldo/keto reductase 2720866 5173781 CMM_2417 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldo/keto reductase YP_001223162.1 2720024 R 443906 CDS YP_001223163.1 148273602 5173485 complement(2720863..2722449) 1 NC_009480.1 putative long-chain-fatty-acid-CoA ligase (ZP_00294061.1| COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Thermobifida fusca]; NP_822779.1| putative acyl-CoA synthetase, long-chain fatty acid:CoA ligase [Streptomyces avermitilis MA-4680]). pfam00501, AMP-binding, AMP-binding enzyme. InterPro: AMP-dependent synthetase and ligase.; Specificity unclear; putative long-chain-fatty-acid-CoA ligase 2722449 fadD 5173485 fadD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative long-chain-fatty-acid-CoA ligase YP_001223163.1 2720863 R 443906 CDS YP_001223164.1 148273603 5174959 2722590..2726408 1 NC_009480.1 putative ATP-dependent helicase (CAG20164.1| putative ATP-dependent helicase HrpA [Photobacterium profundum]; ZP_00292334.1| COG1643: HrpA-like helicases [Thermobifida fusca]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam04408, HA2, Helicase associated domain (HA2). This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent helicase 2726408 5174959 CMM_2419 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent helicase YP_001223164.1 2722590 D 443906 CDS YP_001223165.1 148273604 5174220 2726599..2728137 1 NC_009480.1 putative peptide ABC transporter, substrate-binding protein (NP_631716.1| putative secreted solute-binding protein [Streptomyces coelicolor A3(2)]; ZP_00278819.1| COG0747: ABC-type dipeptide transport system, periplasmic component [Burkholderia fungorum LB400]). pfam00496,SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5. InterPro: Bacterial extracellular solute-binding protein family 5.; Specificity unclear; putative peptide ABC transporter, substrate-binding protein 2728137 5174220 CMM_2420 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, substrate-binding protein YP_001223165.1 2726599 D 443906 CDS YP_001223166.1 148273605 5173926 2728134..2729108 1 NC_009480.1 putative peptide ABC transporter, permease component ( NP_631717.1| putative metal transport integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00303394.1| COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Novosphingobium aromaticivorans DSM 12444]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 2729108 5173926 CMM_2421 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001223166.1 2728134 D 443906 CDS YP_001223167.1 148273606 5174677 2729105..2729929 1 NC_009480.1 putative peptide ABC transporter, permease component (ZP_00364680.1| COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Polaromonas sp. JS666]; NP_105840.1| ABC transporter, permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative peptide ABC transporter, permease component 2729929 5174677 CMM_2422 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001223167.1 2729105 D 443906 CDS YP_001223168.1 148273607 5173660 2729926..2731371 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_631719.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_790103.1| peptide ABC transporter, ATP-binding protein [Pseudomonas syringae pv. tomato str. DC3000]). pfam00005, ABC_tran,ABC transporter (duplicated).; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 2731371 5173660 CMM_2423 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001223168.1 2729926 D 443906 CDS YP_001223169.1 148273608 5174102 complement(2731414..2732382) 1 NC_009480.1 hypothetical protein 2732382 5174102 CMM_2424 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223169.1 2731414 R 443906 CDS YP_001223170.1 148273609 5175416 complement(2732379..2732978) 1 NC_009480.1 conserved membrane protein (NP_629518.1| putative membrane protein [Streptomyces coelicolor A3(2)]; YP_080528.1| hypothetical protein BL02151 [Bacillus licheniformis DSM 13]).; Conserved hypothetical protein; hypothetical protein 2732978 5175416 CMM_2425 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223170.1 2732379 R 443906 CDS YP_001223171.1 148273610 5174414 complement(2733969..2734817) 1 NC_009480.1 putative thiosulfate sulfurtransferase (YP_117233.1| putative thiosulfate sulfurtransferase [Nocardia farcinica]; ZP_00199189.1| COG2897: Rhodanese-related sulfurtransferase [Kineococcus radiotolerans SRS30216]). pfam00581, Rhodanese, Rhodanese-like domain (twice).; Specificity unclear; putative thiosulfate sulfurtransferase 2734817 sseB 5174414 sseB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thiosulfate sulfurtransferase YP_001223171.1 2733969 R 443906 CDS YP_001223172.1 148273611 5175899 complement(2734846..2735379) 1 NC_009480.1 putative acetyltransferase (ZP_00057878.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Thermobifida fusca]; NP_627391.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2735379 5175899 CMM_2427 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223172.1 2734846 R 443906 CDS YP_001223173.1 148273612 5175791 complement(2735514..2736509) 1 NC_009480.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2736509 nrdF 5175791 nrdF Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonucleotide-diphosphate reductase subunit beta YP_001223173.1 2735514 R 443906 CDS YP_001223174.1 148273613 5174796 complement(2736681..2739185) 1 NC_009480.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2739185 nrdA 5174796 nrdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 ribonucleotide-diphosphate reductase subunit alpha YP_001223174.1 2736681 R 443906 CDS YP_001223175.1 148273614 5173510 2739562..2740773 1 NC_009480.1 putative MFS permease (YP_062629.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787812.1| putative efflux protein [Tropheryma whipplei str. Twist]).; Function unclear; putative MFS permease 2740773 5173510 CMM_2430 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001223175.1 2739562 D 443906 CDS YP_001223176.1 148273615 5174043 2740869..2741342 1 NC_009480.1 hypothetical protein 2741342 5174043 CMM_2431 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223176.1 2740869 D 443906 CDS YP_001223177.1 148273616 5175467 complement(2741410..2742402) 1 NC_009480.1 putative aldo/keto reductase (NP_631342.1| putative oxidoreducatse [Streptomyces coelicolor A3(2)]; ZP_00294378.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Thermobifida fusca]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity. InterPro: Aldo/keto reductase family.; Function unclear; putative aldo/keto reductase 2742402 5175467 CMM_2432 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldo/keto reductase YP_001223177.1 2741410 R 443906 CDS YP_001223178.1 148273617 5174591 complement(2742412..2742984) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2742984 5174591 CMM_2433 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223178.1 2742412 R 443906 CDS YP_001223179.1 148273618 5175739 2743501..2744685 1 NC_009480.1 putative secreted serine protease, family S1C (NP_853797.1| PROBABLE SERINE PROTEASE PEPA [Mycobacterium bovis AF2122/97]; YP_121441.1| putative protease [Nocardia farcinica]). pfam00089, Trypsin, Trypsin. pfam00595, PDZ, PDZ domain (Also known as DHR or GLGF). PDZ domains are found in diverse signaling proteins.; Function unclear; secreted serine protease 2744685 5175739 CMM_2434 Clavibacter michiganensis subsp. michiganensis NCPPB 382 secreted serine protease YP_001223179.1 2743501 D 443906 CDS YP_001223180.1 148273619 5173255 complement(2744756..2746294) 1 NC_009480.1 putative alpha-L-arabinofuranosidase (Arabinosidase) (ZP_00199261.1| COG3534: Alpha-L-arabinofuranosidase [Kineococcus radiotolerans SRS30216]; NP_626674.1| alpha-L-arabinofuranosidase [Streptomyces coelicolor A3(2)]). , pfam06964, Alpha-L-AF_C, Alpha-L-arabinofuranosidase C-terminus.; Specificity unclear; putative alpha-L-arabinofuranosidase 2746294 abfA2 5173255 abfA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alpha-L-arabinofuranosidase YP_001223180.1 2744756 R 443906 CDS YP_001223181.1 148273620 5173005 complement(2746389..2747309) 1 NC_009480.1 putative L-arabinose ABC transporter, permease component (NP_631551.1| putative integral membrane binding-protein-dependent transport protein [Streptomyces coelicolor A3(2)]; NP_437582.1| putative sugar uptake ABC transporter permease protein [Sinorhizobium meliloti 1021]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative L-arabinose ABC transporter, permease component 2747309 5173005 CMM_2436 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-arabinose ABC transporter, permease component YP_001223181.1 2746389 R 443906 CDS YP_001223182.1 148273621 5173001 complement(2747306..2748250) 1 NC_009480.1 putative L-arabinose ABC transporter, permease component (NP_631550.1| putative integral membrane binding-protein-dependent transport protein [Streptomyces coelicolor A3(2)]; NP_470102.1|; Specificity unclear; putative L-arabinose ABC transporter, permease component 2748250 5173001 CMM_2437 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-arabinose ABC transporter, permease component YP_001223182.1 2747306 R 443906 CDS YP_001223183.1 148273622 5175697 complement(2748345..2749694) 1 NC_009480.1 putative L-arabinose ABC transporter, substrate binding protein (NP_631549.1| putative extracellular solute-binding protein [Streptomyces coelicolor A3(2)]; NP_437584.1| putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti 1021]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein.; Specificity unclear; putative L-arabinose ABC transporter, substrate binding protein 2749694 5175697 CMM_2438 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-arabinose ABC transporter, substrate binding protein YP_001223183.1 2748345 R 443906 CDS YP_001223184.1 148273623 5175657 complement(2749799..2750800) 1 NC_009480.1 putative transcriptional regulator, LacI family (NP_625360.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00198050.1| COG1609: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 2750800 5175657 CMM_2439 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001223184.1 2749799 R 443906 CDS YP_001223185.1 148273624 5173319 2750921..2751358 1 NC_009480.1 hypothetical protein (YP_061780.1| hypothetical protein Lxx07550 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2751358 5173319 CMM_2440 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223185.1 2750921 D 443906 CDS YP_001223186.1 148273625 5175180 complement(2751378..2751773) 1 NC_009480.1 conserved membrane protein (NP_962814.1| hypothetical protein MAP3880 [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00291826.1| COG0477: Permeases of the major facilitator superfamily [Thermobifida fusca]).; hypothetical protein 2751773 5175180 CMM_2441 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223186.1 2751378 R 443906 CDS YP_001223187.1 148273626 5175815 complement(2751783..2753402) 1 NC_009480.1 putative methyltransferase (NP_627743.1| putative transferase [Streptomyces coelicolor A3(2)]; ZP_00292538.1| COG2890: Methylase of polypeptide chain release factors [Thermobifida fusca]). Interpro: SAM (and some other nucleotide) binding motif.; Family membership; putative methyltransferase 2753402 5175815 CMM_2442 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methyltransferase YP_001223187.1 2751783 R 443906 CDS YP_001223188.1 148273627 5175428 complement(2753479..2755086) 1 NC_009480.1 putative secreted cellulase containing cellulose-binding domain (endo-1,4-beta-glucanase) (CAA44467.2| Cellulase [Clavibacter michiganensis]; YP_063040.1| cellulase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5). smart00637, CBD_II, CBD_II domain. InterPro: Glycoside hydrolase family 5.; Specificity unclear; cellulase 2755086 celB 5175428 celB Clavibacter michiganensis subsp. michiganensis NCPPB 382 cellulase YP_001223188.1 2753479 R 443906 CDS YP_001223189.1 148273628 5175687 complement(2755424..2756392) 1 NC_009480.1 putative membrane protein (YP_061659.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789610.1| putative integral membrane protein [Tropheryma whipplei TW08/27]).; Conserved hypothetical protein; hypothetical protein 2756392 5175687 CMM_2444 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223189.1 2755424 R 443906 CDS YP_001223190.1 148273629 5175968 complement(2756479..2757147) 1 NC_009480.1 putative acetyltransferase (YP_061658.1| ribosomal-protein-alanine N-acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059290.1| COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins [Thermobifida fusca]; NP_824846.1| putative ribosomal- protein-alanine N-acetyltransferase [Streptomyces avermitilis MA-4680]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2757147 5175968 CMM_2445 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223190.1 2756479 R 443906 CDS YP_001223191.1 148273630 5173745 complement(2757205..2758101) 1 NC_009480.1 putative UTP-glucose-1-phosphate uridylyltransferase (YP_061657.1| UTP-glucose-1-phosphate uridylyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824850.1| putative UTP-glucose-1-phosphate uridylyltransferase [Streptomyces avermitilis MA-4680]). pfam00483, NTP_transferase, Nucleotidyl transferase. This family includes a wide range of enzymes which transfer nucleotides onto phosphosugars.; High confidence in function and specificity; putative UTP-glucose-1-phosphate uridylyltransferase 2758101 galU 5173745 galU Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative UTP-glucose-1-phosphate uridylyltransferase YP_001223191.1 2757205 R 443906 CDS YP_001223192.1 148273631 5174889 2758142..2758717 1 NC_009480.1 putative 5-formyltetrahydrofolate cyclo-ligase (YP_061656.1| 5-formyltetrahydrofolate cyclo-ligase-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600108.1| 5-formyltetrahydrofolate cyclo-ligase [Corynebacterium glutamicum ATCC 13032]). pfam01812, 5-FTHF_cyc-lig, 5-formyltetrahydrofolate cyclo-ligase family. InterPro: 5-formyltetrahydrofolate cyclo-ligase.; Function unclear; putative 5-formyltetrahydrofolate cyclo-ligase 2758717 5174889 CMM_2447 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 5-formyltetrahydrofolate cyclo-ligase YP_001223192.1 2758142 D 443906 CDS YP_001223193.1 148273632 5173353 2758724..2759131 1 NC_009480.1 conserved hypothetical protein (only N-terminal similarities; NP_335453.1| hypothetical protein MT1020 [Mycobacterium tuberculosis CDC1551]; NP_627401.1| conserved hypothetical protein SCE22.04 [Streptomyces coelicolor A3(2);).; hypothetical protein 2759131 5173353 CMM_2448 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223193.1 2758724 D 443906 CDS YP_001223194.1 148273633 5175289 2759160..2759642 1 NC_009480.1 putative large-conductance mechanosensitive channel (YP_061654.1| large-conductance mechanosensitive channel [Leifsonia xyli subsp. xyli str. CTCB07]; NP_939223.1| large-conductance mechanosensitive channel [Corynebacterium diphtheriae]; NP_627404.1| putative mechanosensitive channel [Streptomyces coelicolor A3(2)]). pfam01741, MscL, Large-conductance mechanosensitive channel, MscL. InterPro: Large-conductance mechanosensitive channel mscL.; Function unclear; putative large-conductance mechanosensitive channel 2759642 5175289 CMM_2449 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative large-conductance mechanosensitive channel YP_001223194.1 2759160 D 443906 CDS YP_001223195.1 148273634 5175666 complement(2759950..2763675) 1 NC_009480.1 conserved hypothetical protein (YP_061653.1| hypothetical protein Lxx05870 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789612.1| conserved large hypothetical protein [Tropheryma whipplei TW08/27]).; Family membership; hypothetical protein 2763675 5175666 CMM_2451 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223195.1 2759950 R 443906 CDS YP_001223196.1 148273635 5175451 2764021..2764482 1 NC_009480.1 putative fusion protein containg a putative transcriptional regulator, Cro/CI family and a nucleotidyltransferase (ZP_00186470.1| COG1396: Predicted transcriptional regulators [Rubrobacter xylanophilus DSM 9941]; AAP86029.1| putative nucleotidyl-transferase [Ralstonia eutropha]). N-terminal: pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif. C-terminal: pfam01909, NTP_transf_2,Nucleotidyltransferase domain.; Conserved hypothetical protein; Cro/CI family transcriptional regulator /nucleotidyltransferase 2764482 5175451 CMM_2452 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator /nucleotidyltransferase YP_001223196.1 2764021 D 443906 CDS YP_001223197.1 148273636 5174536 2764482..2764814 1 NC_009480.1 conserved hypothetical protein (ZP_00178030.1| COG2361: Uncharacterized conserved protein [Crocosphaera watsonii WH 8501]; NP_634631.1| nucleotidyltransferase [Methanosarcina mazei Go1]). pfam01934, DUF86, Protein of unknown function DUF86.; hypothetical protein 2764814 5174536 CMM_2453 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223197.1 2764482 D 443906 CDS YP_001223198.1 148273637 5175737 complement(2764825..2765937) 1 NC_009480.1 conserved hypothetical protein, putative restriction enzyme (ZP_00128036.1| COG4748: Uncharacterized conserved protein [Pseudomonas syringae pv. syringae B728a]; NP_801082.1| hypothetical protein VPA1572 [Vibrio parahaemolyticus RIMD 2210633]; NP_601625.1| predicted type IV restriction endonuclease [Corynebacterium glutamicum ATCC 13032]). pfam04313,HSDR_N, Type I restriction enzyme R protein N terminus (HSDR_N). This family consists of a number of N terminal regions found in type I restriction enzyme R (HSDR) proteins.; Function unclear; putative restriction enzyme 2765937 5175737 CMM_2454 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative restriction enzyme YP_001223198.1 2764825 R 443906 CDS YP_001223199.1 148273638 5175047 2766824..2768191 1 NC_009480.1 putative cytosine/purine permease, NCS1 family (NP_624885.1| putative cytosine permease [Streptomyces coelicolor A3(2)]; YP_049041.1| permease [Erwinia carotovora subsp. atroseptica SCRI1043]). pfam02133,Transp_cyt_pur, Permease for cytosine/purines, uracil,thiamine, allantoin.; Specificity unclear; cytosine/purine permease NCS1 family 2768191 5175047 CMM_2455 Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytosine/purine permease NCS1 family YP_001223199.1 2766824 D 443906 CDS YP_001223200.1 148273639 5175519 2768188..2769747 1 NC_009480.1 putative hydantoinase (NP_085687.1| hydantoinase [Mesorhizobium loti MAFF303099]; NP_242750.1| hydantoinase [Bacillus halodurans C-125]). pfam05378,Hydant_A_N, Hydantoinase/oxoprolinase N-terminal region. pfam01968, Hydantoinase_A, Hydantoinase/oxoprolinase. This family includes the enzymes hydantoinase and oxoprolinase EC:3.5.2.9. Both reactions involve the hydrolysis of 5-membered rings via hydrolysis of their internal imide bonds.; Specificity unclear; putative hydantoinase 2769747 5175519 CMM_2456 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydantoinase YP_001223200.1 2768188 D 443906 CDS YP_001223201.1 148273640 5175480 2769740..2770855 1 NC_009480.1 conserved hypothetical protein (YP_013096.1| conserved hypothetical protein [Listeria monocytogenes str. 4b F2365]; ZP_00197761.1| COG3535: Uncharacterized conserved protein [Mesorhizobium sp. BNC1]). pfam06032,DUF917, Protein of unknown function (DUF917).; Function unclear; hypothetical protein 2770855 5175480 CMM_2457 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223201.1 2769740 D 443906 CDS YP_001223202.1 148273641 5174060 2770882..2771997 1 NC_009480.1 conserved hypothetical protein (EAL09859.1| conserved hypothetical protein [Listeria monocytogenes str. 4b H7858] ; NP_085686.1| hypothetical protein mll9130 [Mesorhizobium loti MAFF303099]). pfam06032, DUF917,Protein of unknown function (DUF917).; hypothetical protein 2771997 5174060 CMM_2458 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223202.1 2770882 D 443906 CDS YP_001223203.1 148273642 5173670 2771994..2773559 1 NC_009480.1 conserved hypothetical protein, putative regulatory protein (ZP_00059062.1| COG2508: Regulator of polyketide synthase expression [Thermobifida fusca]; NP_631097.1| putative regulatory protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 2773559 5173670 CMM_2459 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223203.1 2771994 D 443906 CDS YP_001223204.1 148273643 5173889 complement(2773568..2775175) 1 NC_009480.1 Function unclear; putative ATPase 2775175 5173889 CMM_2460 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATPase YP_001223204.1 2773568 R 443906 CDS YP_001223205.1 148273644 5175078 2775387..2776169 1 NC_009480.1 conserved hypothetical protein (ZP_00063576.1| COG0009: Putative translation factor (SUA5) [Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293]; NP_781010.1| SUA5 protein [Clostridium tetani E88]). pfam01300, Sua5_yciO_yrdC, yrdC domain. This domain has been shown to preferentially bind to dsRNA.; Function unclear; hypothetical protein 2776169 5175078 CMM_2461 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223205.1 2775387 D 443906 CDS YP_001223206.1 148273645 5172917 2776527..2776877 1 NC_009480.1 conserved hypothetical protein, putative Lsr2-like protein (YP_062335.1| hypothetical protein Lxx14130 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00198461.1| hypothetical protein Krad06003802 [Kineococcus radiotolerans SRS30216]; YP_118525.1| putative LSR2 protein [Nocardia farcinica]).; Function unclear; putative Lsr2-like protein 2776877 5172917 CMM_2462 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Lsr2-like protein YP_001223206.1 2776527 D 443906 CDS YP_001223207.1 148273646 5175335 2777098..2778465 1 NC_009480.1 hypothetical protein (weak similarity to low GC Gram-positive surface proteins and RTX toxins).; hypothetical protein 2778465 5175335 CMM_2463 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223207.1 2777098 D 443906 CDS YP_001223208.1 148273647 5175427 2778699..2779463 1 NC_009480.1 putative transcriptional activator (NP_821574.1| putative transcriptional regulator [Streptomyces avermitilis MA-4680]; AAP42853.1| NanR1 [Streptomyces nanchangensis]). pfam03704, BTAD, Bacterial transcriptional activator domain. Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production.; Function unclear; putative transcriptional activator 2779463 5175427 CMM_2464 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional activator YP_001223208.1 2778699 D 443906 CDS YP_001223209.1 148273648 5175157 complement(2779506..2781578) 1 NC_009480.1 putative serine protease, family S9A (NP_638852.1| prolyl oligopeptidase [Xanthomonas campestris pv. campestris str. ATCC 33913]; NP_962885.1| hypothetical protein MAP3951c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam02897, Peptidase_S9_N,Prolyl oligopeptidase, N-terminal beta-propeller domain. pfam00326, Peptidase_S9, Prolyl oligopeptidase family. InterPro: Prolyl oligopeptidase N-terminal beta-propeller domain.; Specificity unclear; serine protease 2781578 5175157 CMM_2465 Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001223209.1 2779506 R 443906 CDS YP_001223210.1 148273649 5174873 complement(2781613..2782110) 1 NC_009480.1 putative restriction endonuclease (YP_062634.1| hypothetical protein Lxx17860 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_961224.1| hypothetical protein MAP2290c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00058752.1| COG1403: Restriction endonuclease [Thermobifida fusca]). pfam01844, HNH, HNH endonuclease. InterPro: HNH nuclease.; Specificity unclear; putative restriction endonuclease 2782110 5174873 CMM_2466 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative restriction endonuclease YP_001223210.1 2781613 R 443906 CDS YP_001223211.1 148273650 5173128 complement(2782470..2783414) 1 NC_009480.1 putative secreted hydrolase (NP_787417.1| NPL/P60 family secreted protein [Tropheryma whipplei str. Twist]; NP_780938.1| putative cell wall-associated hydrolase [Clostridium tetani E88]). pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.; Function unclear; putative secreted hydrolase 2783414 5173128 CMM_2467 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative secreted hydrolase YP_001223211.1 2782470 R 443906 CDS YP_001223212.1 148273651 5174990 complement(2783738..2784436) 1 NC_009480.1 putative iron-dependent repressor (YP_062636.1| iron-dependent repressor, DxtR metalloregulatory family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628563.1| iron repressor [Streptomyces coelicolor A3(2)]; AAF36925.1| transcriptional regulatory protein DtxR [Rhodococcus erythropolis]). pfam01325, Fe_dep_repress,Iron dependent repressor, N-terminal DNA binding domain. This family includes the Diphtheria toxin repressor. DNA binding is through a helix-turn-helix motif. pfam02742,Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain. This family includes the Diphtheria toxin repressor. pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.; Specificity unclear; putative iron-dependent repressor 2784436 dtxR 5174990 dtxR Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-dependent repressor YP_001223212.1 2783738 R 443906 CDS YP_001223213.1 148273652 5173362 2784545..2785663 1 NC_009480.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 2785663 serC 5173362 serC Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoserine aminotransferase YP_001223213.1 2784545 D 443906 CDS YP_001223214.1 148273653 5173279 complement(2785736..2786401) 1 NC_009480.1 conserved hypothetical protein (YP_062639.1| hypothetical protein Lxx17910 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055188.1| hypothetical protein PPA0478 [Propionibacterium acnes KPA171202]).; hypothetical protein 2786401 5173279 CMM_2470 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223214.1 2785736 R 443906 CDS YP_001223215.1 148273654 5173157 complement(2786394..2786777) 1 NC_009480.1 putative cold-shock protein (YP_062640.1| cold shock protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00059156.1| COG1278: Cold shock proteins [Thermobifida fusca]; NP_628496.1| cold shock protein B [Streptomyces coelicolor A3(2)]). pfam00313, CSD, 'Cold-shock' DNA-binding domain. smart00357, CSP, Cold shock protein domain; RNA-binding domain that functions as a RNA-chaperone in bacteria and is involved in regulating translation in eukaryotes. Contains sub-family of RNA-binding domains in the Rho transcription termination factor. InterPro: Cold-shock DNA-binding domain.; Function unclear; putative cold shock protein 2786777 cspB 5173157 cspB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cold shock protein YP_001223215.1 2786394 R 443906 CDS YP_001223216.1 148273655 5174978 2786936..2787205 1 NC_009480.1 hypothetical membrane protein (YP_062641.1| hypothetical protein Lxx17930 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2787205 5174978 CMM_2472 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223216.1 2786936 D 443906 CDS YP_001223217.1 148273656 5173196 2787216..2789102 1 NC_009480.1 putative DNA binding protein (YP_062642.1| hypothetical protein Lxx17940 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302419.1| possible DNA-binding protein [Mycobacterium leprae]; NP_737502.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein 2789102 5173196 CMM_2473 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223217.1 2787216 D 443906 CDS YP_001223218.1 148273657 5174494 2789099..2790763 1 NC_009480.1 putative ATP-dependent DNA helicase (YP_062643.1| DNA repair helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825089.1| putative ATP-dependent DNA helicase [Streptomyces avermitilis MA-4680]; ZP_00226628.1| COG1061: DNA or RNA helicases of superfamily II [Kineococcus radiotolerans SRS30216]). pfam00270, DEAD,DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent DNA helicase 2790763 5174494 CMM_2474 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent DNA helicase YP_001223218.1 2789099 D 443906 CDS YP_001223219.1 148273658 5175503 2790841..2791533 1 NC_009480.1 putative two component system response regulator (YP_062646.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787175.1| two-component system response regulator [Tropheryma whipplei str. Twist]; ZP_00198812.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; Specificity unclear; putative two component system response regulator 2791533 5175503 CMM_2475 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two component system response regulator YP_001223219.1 2790841 D 443906 CDS YP_001223220.1 148273659 5173163 2791654..2793414 1 NC_009480.1 putative two-component system sensor kinase (YP_062647.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226631.1| COG0642: Signal transduction histidine kinase [Kineococcus radiotolerans SRS30216]; ZP_00081281.1| COG0642: Signal transduction histidine kinase [Geobacter metallireducens]). pfam00672, HAMP, HAMP domain. pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2793414 5173163 CMM_2476 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001223220.1 2791654 D 443906 CDS YP_001223221.1 148273660 5173173 2793461..2793751 1 NC_009480.1 conserved hypothetical protein, 6 kDa early secretory antigenic target (ESAT-6) homolog (ZP_00198816.2| COG4842: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]; NP_695234.1| hypothetical protein BL0003 [Bifidobacterium longum NCC2705]). pfam06013, DUF909, Bacterial protein of unknown function (DUF909). This family consists of several short bacterial proteins of unknown function.; Function unclear; hypothetical protein 2793751 5173173 CMM_2477 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223221.1 2793461 D 443906 CDS YP_001223222.1 148273661 5173120 complement(2793882..2795501) 1 NC_009480.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 2795501 groEL 5173120 groEL Clavibacter michiganensis subsp. michiganensis NCPPB 382 chaperonin GroEL YP_001223222.1 2793882 R 443906 CDS YP_001223223.1 148273662 5173973 complement(2795691..2795909) 1 NC_009480.1 putative cold shock protein (YP_062650.1| cold-shock protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825109.1| putative cold shock protein [Streptomyces avermitilis MA-4680]; ZP_00228151.1| COG1278: Cold shock proteins [Kineococcus radiotolerans SRS30216]). pfam00313,CSD, 'Cold-shock' DNA-binding domain. InterPro: Cold-shock DNA-binding domain.; Function unclear; putative cold shock protein 2795909 cspA2 5173973 cspA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cold shock protein YP_001223223.1 2795691 R 443906 CDS YP_001223224.1 148273663 5175148 complement(2796130..2796702) 1 NC_009480.1 hypothetical protein (YP_062651.1| hypothetical protein Lxx18030 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_334855.1| tuberculin related peptide [Mycobacterium tuberculosis CDC1551]; NP_940367.1| Putative secreted protein [Corynebacterium diphtheriae NCTC 13129]). 2a75: L-lysine exporter; hypothetical protein 2796702 5175148 CMM_2480 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223224.1 2796130 R 443906 CDS YP_001223225.1 148273664 5173851 complement(2796737..2797066) 1 NC_009480.1 conserved hypothetical protein (YP_062652.1| hypothetical protein Lxx18040 [Leifsonia xyli subsp. xyli str. CTCB07]; CAB06570.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]; ZP_00059146.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 2797066 5173851 CMM_2481 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223225.1 2796737 R 443906 CDS YP_001223226.1 148273665 5174289 2797303..2797704 1 NC_009480.1 conserved hypothetical protein, putative methionine sulfoxide reductase (YP_062653.1| oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_630170.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; CAB02327.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress.; Function unclear; putative methionine sulfoxide reductase 2797704 5174289 CMM_2482 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methionine sulfoxide reductase YP_001223226.1 2797303 D 443906 CDS YP_001223227.1 148273666 5173619 2797710..2798309 1 NC_009480.1 conserved hypothetical protein, putative nitroreductase (YP_062654.1| nitroreductase [Leifsonia xyli subsp. xyli str. CTCB07]P24250|YDJA_ECOLI Protein ydjA; NP_460262.1| putative oxidoreductase [Salmonella typhimurium LT2]). pfam00881, Nitroreductase,Nitroreductase family. Members of this family utilise FMN as a cofactor.; Function unclear; putative nitroreductase 2798309 5173619 CMM_2483 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nitroreductase YP_001223227.1 2797710 D 443906 CDS YP_001223228.1 148273667 5174818 complement(2798439..2799356) 1 NC_009480.1 conserved hypothetical protein (YP_062663.1| hypothetical protein Lxx18180 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789357.1| putative secreted protein [Tropheryma whipplei TW08/27]).; Function unclear; hypothetical protein 2799356 5174818 CMM_2484 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223228.1 2798439 R 443906 CDS YP_001223229.1 148273668 5174158 2799672..2800772 1 NC_009480.1 putative sugar ABC transporter, ATP-binding protein (YP_062664.1| glycerol-phosphate porter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628414.1| ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Function unclear; putative sugar ABC transporter, ATP-binding protein 2800772 5174158 CMM_2485 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATP-binding protein YP_001223229.1 2799672 D 443906 CDS YP_001223230.1 148273669 5174189 2800874..2802178 1 NC_009480.1 conserved hypothetical protein (YP_062665.1| hypothetical protein Lxx18190 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_938914.1| hypothetical protein DIP0538 [Corynebacterium diphtheriae NCTC 13129]).; hypothetical protein 2802178 5174189 CMM_2486 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223230.1 2800874 D 443906 CDS YP_001223231.1 148273670 5173357 complement(2802251..2803321) 1 NC_009480.1 putative tRNA/rRNA methyltransferase (ZP_00225978.1| COG0566: rRNA methylases [Kineococcus radiotolerans SRS30216]; NP_601840.1| rRNA methylase [Corynebacterium glutamicum ATCC 13032]). InterPro: RNA methyltransferase TrmH family group 3 pfam00588,SpoU_methylase, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet. TIGRFam: rRNA_methyl_3: RNA methyltransferase; Specificity unclear; putative tRNA/rRNA methyltransferase 2803321 5173357 CMM_2487 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative tRNA/rRNA methyltransferase YP_001223231.1 2802251 R 443906 CDS YP_001223232.1 148273671 5173056 complement(2803311..2804765) 1 NC_009480.1 cysS1; catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 2804765 cysS 5173056 cysS Clavibacter michiganensis subsp. michiganensis NCPPB 382 cysteinyl-tRNA synthetase YP_001223232.1 2803311 R 443906 CDS YP_001223233.1 148273672 5174582 complement(2804849..2806081) 1 NC_009480.1 putative IspDF bifunctional enzyme (N-terminally: COG1211, IspD, 4-diphosphocytidyl- 2-methyl-D-erithritol synthase, EC 2.7.7.60; C-terminally: COG0245, IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, EC 4.6.1.12) (NP_787476.1| IspD; IspF [Tropheryma whipplei str. Twist]; NP_698125.1| 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/ 4-diphosphocytidyl-2C-methyl-D-erythritol synthase [Brucella suis 1330]). Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate (ispD) and converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 24- cyclodiphosphate and CMP (ispF). Also converts 4-diphosphocytidyl- 2C-methyl-D-erythritol into 2C-methyl-D-erythritol 34- cyclophosphate and CMP (ispF) (By similarity). InterPro: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase ispD: 4-diphosphocytidyl-2C-methyl-D-e; High confidence in function and specificity; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2806081 ispDF 5174582 ispDF Clavibacter michiganensis subsp. michiganensis NCPPB 382 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_001223233.1 2804849 R 443906 CDS YP_001223234.1 148273673 5173812 complement(2806125..2806607) 1 NC_009480.1 putative transcriptional regulator, CarD family (ZP_00198110.2| COG1329: Transcriptional regulators, ; NP_301347.1| putative transcription factor [Mycobacterium leprae]). InterPro: Transcription factor CarD pfam02559,CarD_TRCF, CarD-like/TRCF domain. CarD is a Myxococcus xanthus protein required for the activation of light- and starvation- inducible genes. This domain is involved in binding to the stalled RNA polymerase.; Specificity unclear; CarD family transcriptional regulator 2806607 5173812 CMM_2490 Clavibacter michiganensis subsp. michiganensis NCPPB 382 CarD family transcriptional regulator YP_001223234.1 2806125 R 443906 CDS YP_001223235.1 148273674 5173686 2806771..2807337 1 NC_009480.1 hypothetical protein 2807337 5173686 CMM_2491 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223235.1 2806771 D 443906 CDS YP_001223236.1 148273675 5175436 complement(2807423..2808103) 1 NC_009480.1 putative two-component system response regulator (CAB00952.1| TWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY)[Mycobacterium tuberculosis H37Rv]; NP_938772.1| Putative two component system response regulator [Corynebacterium diphtheriae]). pfam00072, Response_reg,Response regulator receiver domain. pfam00486,Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system response regulator 2808103 5175436 CMM_2492 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001223236.1 2807423 R 443906 CDS YP_001223237.1 148273676 5173109 complement(2808100..2809263) 1 NC_009480.1 two-component system sensor kinase (NP_825150.1| putative two-component system sensor kinase [Streptomyces avermitilis MA-4680]; ZP_00058811.1| COG0642: Signal transduction histidine kinase [Thermobifida fusca]). InterPro: Histidine kinase C-terminal pfam00512, HisKA,His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518,HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.; Specificity unclear; putative two-component system sensor kinase 2809263 5173109 CMM_2493 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system sensor kinase YP_001223237.1 2808100 R 443906 CDS YP_001223238.1 148273677 5173073 2809468..2810121 1 NC_009480.1 putative phosphate transport system regulator (NP_825151.1| putative phosphate transport system regulatory protein [Streptomyces avermitilis MA-4680]; ZP_00225901.1| COG0704: Phosphate uptake regulator [Kineococcus radiotolerans SRS30216]). pfam01895, PhoU,PhoU family. This family contains phosphate regulatory proteins including PhoU. (twice); High confidence in function and specificity; putative phosphate transport system regulator 2810121 phoU 5173073 phoU Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphate transport system regulator YP_001223238.1 2809468 D 443906 CDS YP_001223239.1 148273678 5173777 complement(2810206..2810961) 1 NC_009480.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2810961 gpmA 5173777 gpmA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglyceromutase YP_001223239.1 2810206 R 443906 CDS YP_001223240.1 148273679 5175683 2810997..2811809 1 NC_009480.1 putative methylase (ZP_00198230.1| COG2890: Methylase of polypeptide chain release factors [Kineococcus radiotolerans SRS30216]; NP_825184.1| hypothetical protein SAV4007 [Streptomyces avermitilis MA-4680]). InterPro: SAM (and some other nucleotide) binding motif surE: stationary-phase survival protein; Function unclear; hypothetical protein 2811809 5175683 CMM_2496 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223240.1 2810997 D 443906 CDS YP_001223241.1 148273680 5175186 complement(2811806..2812927) 1 NC_009480.1 putative membrane protein (ZP_00227637.1| COG4129: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_739210.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]).; Function unclear; hypothetical protein 2812927 5175186 CMM_2497 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223241.1 2811806 R 443906 CDS YP_001223242.1 148273681 5173330 complement(2812911..2814065) 1 NC_009480.1 putative aminomethyltransferase (ZP_00198226.1| COG0354: Predicted aminomethyltransferase related to GcvT [Kineococcus radiotolerans SRS30216]; NP_825205.1| hypothetical protein SAV4028 [Streptomyces avermitilis MA-4680]). InterPro: Glycine cleavage T-protein (aminomethyl transferase). gcvT: glycine cleavage system T protein. pfam01571, GCV_T, Glycine cleavage T-protein (aminomethyl transferase).; Function unclear; putative aminomethyltransferase 2814065 5173330 CMM_2498 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aminomethyltransferase YP_001223242.1 2812911 R 443906 CDS YP_001223243.1 148273682 5173663 complement(2814055..2814654) 1 NC_009480.1 conserved hypothetical protein (ZP_00198224.2| hypothetical protein Krad06004263 [Kineococcus radiotolerans SRS30216]; ZP_00293141.1| COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) [Thermobifida fusca]).; hypothetical protein 2814654 5173663 CMM_2499 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223243.1 2814055 R 443906 CDS YP_001223244.1 148273683 5173591 complement(2814666..2814782) 1 NC_009480.1 hypothetical protein (ZP_01130428.1| hypothetical protein A20C1_06691 [marine actinobacterium PHSC20C1]; AAT89577.1| hypothetical protein Lxx18360 [Leifsonia xyli subsp. xyli str. CTCB07]); hypothetical protein 2814782 5173591 CMM_2499A Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223244.1 2814666 R 443906 CDS YP_001223245.1 148273684 5173894 complement(2814826..2815092) 1 NC_009480.1 Hypothetical protein; hypothetical protein 2815092 5173894 CMM_2500 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223245.1 2814826 R 443906 CDS YP_001223246.1 148273685 5173385 2815146..2815844 1 NC_009480.1 transcriptional regulator (NP_825219.1| putative GlnR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; Q05943|GLNR_STRCO Transcriptional regulatory protein glnR). InterPro: Transcriptional regulatory protein C terminal pfam00486, Trans_reg_C,Transcriptional regulatory protein, C terminal.; Specificity unclear; transcriptional regulator 2815844 glnR 5173385 glnR Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator YP_001223246.1 2815146 D 443906 CDS YP_001223247.1 148273686 5175001 2815807..2816727 1 NC_009480.1 putative acetyltransferase (NP_628328.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; CAA17625.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions (twice). InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 2816727 5175001 CMM_2502 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223247.1 2815807 D 443906 CDS YP_001223248.1 148273687 5173356 2816821..2819004 1 NC_009480.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2819004 ppkA 5173356 ppkA Clavibacter michiganensis subsp. michiganensis NCPPB 382 polyphosphate kinase YP_001223248.1 2816821 D 443906 CDS YP_001223249.1 148273688 5175438 2819046..2819987 1 NC_009480.1 putative NTP pyrophosphohydrolase (NP_961957.1| MutT1 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_600538.1| NTP pyrophosphohydrolase [Corynebacterium glutamicum ATCC 13032]). pfam00293,NUDIX, NUDIX domain. C-terminally second domain: COG2062,SixA, Phosphohistidine phosphatase.; Function unclear; putative NTP pyrophosphohydrolase 2819987 5175438 CMM_2504 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative NTP pyrophosphohydrolase YP_001223249.1 2819046 D 443906 CDS YP_001223250.1 148273689 5173251 2820187..2821284 1 NC_009480.1 phosphate ABC transporter, substrate-binding protein (ZP_00293017.1| COG0226: ABC-type phosphate transport system, periplasmic component [Thermobifida fusca]; NP_695519.1| phosphate-binding transport protein of ABC transporter system [Bifidobacterium longum NCC2705]).; High confidence in function and specificity; phosphate ABC transporter, substrate-binding protein 2821284 pstS 5173251 pstS Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphate ABC transporter, substrate-binding protein YP_001223250.1 2820187 D 443906 CDS YP_001223251.1 148273690 5175608 2821392..2822402 1 NC_009480.1 Phosphate ABC transporter, permease component (ZP_00293018.1| COG0573: ABC-type phosphate transport system, permease component [Thermobifida fusca]; NP_628318.1| phosphate ABC transport system permease protein [Streptomyces coelicolor A3(2)]). InterPro: Binding-protein-dependent transport systems inner membrane component.; High confidence in function and specificity; phosphate ABC transporter permease 2822402 pstC 5175608 pstC Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphate ABC transporter permease YP_001223251.1 2821392 D 443906 CDS YP_001223252.1 148273691 5174080 2822402..2823502 1 NC_009480.1 phosphate ABC transporter, permease component (ZP_00293019.1| COG0581: ABC-type phosphate transport system, permease component [Thermobifida fusca]; NP_825251.1| putative phosphate ABC transporter permease protein [Streptomyces avermitilis MA-4680]). InterPro: Binding-protein-dependent transport systems inner membrane component. pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; High confidence in function and specificity; phosphate ABC transporter, permease component 2823502 pstA 5174080 pstA Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphate ABC transporter, permease component YP_001223252.1 2822402 D 443906 CDS YP_001223253.1 148273692 5174733 2823546..2824325 1 NC_009480.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2824325 pstB 5174733 pstB Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphate transporter ATP-binding protein YP_001223253.1 2823546 D 443906 CDS YP_001223254.1 148273693 5173717 complement(2824407..2825270) 1 NC_009480.1 conserved membrane protein (NP_827759.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00228329.1| hypothetical protein Krad06001631 [Kineococcus radiotolerans SRS30216]). weak similarity to: COG5343, COG5343, Uncharacterized protein conserved in bacteria.; Function unclear; hypothetical protein 2825270 5173717 CMM_2509 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223254.1 2824407 R 443906 CDS YP_001223255.1 148273694 5173541 complement(2825267..2825857) 1 NC_009480.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins; RNA polymerase sigma factor SigK 2825857 sigK 5173541 sigK Clavibacter michiganensis subsp. michiganensis NCPPB 382 RNA polymerase sigma factor SigK YP_001223255.1 2825267 R 443906 CDS YP_001223256.1 148273695 5174421 complement(2826425..2827057) 1 NC_009480.1 hypothetical protein (ZP_00206537.1| hypothetical protein Blon021115 [Bifidobacterium longum DJO10A]; ZP_00226802.1| hypothetical protein Krad06002674 [Kineococcus radiotolerans).; hypothetical protein 2827057 5174421 CMM_2511 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223256.1 2826425 R 443906 CDS YP_001223257.1 148273696 5174046 complement(2827274..2828314) 1 NC_009480.1 putative acyltransferase (NP_945889.1| Acyltransferase 3 family [Rhodopseudomonas palustris CGA009]; NP_738686.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam01757,Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes.; Function unclear; putative acyltransferase 2828314 5174046 CMM_2512 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acyltransferase YP_001223257.1 2827274 R 443906 CDS YP_001223258.1 148273697 5173063 2828591..2829256 1 NC_009480.1 hypothetical esterase (only weak similarities in C-terminal half to: NP_387325.1| PUTATIVE ACYL-COA THIOESTERASE I PROTEIN [Sinorhizobium meliloti 1021]; ZP_00244751.1| COG2755: Lysophospholipase L1 and related esterases [Rubrivivax gelatinosus PM1]). weak similarity to: pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Hypothetical protein; esterase 2829256 5173063 CMM_2513 Clavibacter michiganensis subsp. michiganensis NCPPB 382 esterase YP_001223258.1 2828591 D 443906 CDS YP_001223259.1 148273698 5174016 complement(2829282..2830661) 1 NC_009480.1 hypothetical protein 2830661 5174016 CMM_2514 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223259.1 2829282 R 443906 CDS YP_001223260.1 148273699 5175116 2830903..2831148 1 NC_009480.1 hypothetical protein 2831148 5175116 CMM_2515 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223260.1 2830903 D 443906 CDS YP_001223261.1 148273700 5174804 complement(2831145..2832065) 1 NC_009480.1 putative aldose-1-epimerase (NP_696524.1| hypothetical protein in aldose epimerase family [Bifidobacterium longum NCC2705]; ZP_00291742.1| COG2017: Galactose mutarotase and related enzymes [Thermobifida fusca]). pfam01263, Aldose_epim, Aldose 1-epimerase.; Specificity unclear; putative aldose-1-epimerase 2832065 5174804 CMM_2516 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldose-1-epimerase YP_001223261.1 2831145 R 443906 CDS YP_001223262.1 148273701 5175405 complement(2832076..2832903) 1 NC_009480.1 putative transcriptional regulator, DeoT family (NP_624108.1| Transcriptional regulator of sugar metabolism [Thermoanaerobacter tengcongensis]; ZP_00180163.2| COG1349: Transcriptional regulators of sugar metabolism [Moorella thermoacetica ATCC 39073]). pfam00455, DeoR, Bacterial regulatory proteins, deoR family.; Specificity unclear; DeoR family transcriptional regulator 2832903 5175405 CMM_2517 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DeoR family transcriptional regulator YP_001223262.1 2832076 R 443906 CDS YP_001223263.1 148273702 5175240 2832997..2834139 1 NC_009480.1 Galactose-1-phosphate uridylyltransferase (UDP-glucose-hexose- 1-phosphate uridylyltransferase) (ZP_00226399.1| COG1085: Galactose-1-phosphate uridylyltransferase [Kineococcus radiotolerans SRS30216]; NP_939376.1| Galactose-1-phosphate uridylyltransferase [Corynebacterium diphtheriae NCTC 13129]). InterPro: Galactose-1-phosphate uridyl transferase. pfam01087,GalP_UDP_transf, Galactose-1-phosphate uridyl transferase,N-terminal domain. pfam02744, GalP_UDP_tr_C, Galactose-1-phosphate uridyl transferase, C-terminal domain.; High confidence in function and specificity; hypothetical protein 2834139 galT 5175240 galT Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223263.1 2832997 D 443906 CDS YP_001223264.1 148273703 5174864 2834136..2835296 1 NC_009480.1 Galactokinase (Galactose kinase) (Q9K3S8|GAL1_STRCO Galactokinase (Galactose kinase); ZP_00120571.1| COG0153: Galactokinase [Bifidobacterium longum DJO10A]). InterPro: Galactokinase. pfam00288, GHMP_kinases, GHMP kinases putative ATP-binding protein.; High confidence in function and specificity; hypothetical protein 2835296 galK 5174864 galK Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223264.1 2834136 D 443906 CDS YP_001223265.1 148273704 5174824 2835369..2835974 1 NC_009480.1 putative acetyltransferase (NP_828214.1| putative siderophore binding protein [Streptomyces avermitilis MA-4680]; ZP_00084142.1| COG0663: Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [Pseudomonas fluorescens PfO-1]). InterPro: Bacterial transferase hexapeptide repeat. cd00208, LbetaH,Left-Handed Parallel beta-Helix; Proteins containing hexapeptide repeats are often enzymes showing acyl-transferase activity, many are trimeric in their active form.; Function unclear; putative acetyltransferase/ siderophore binding protein 2835974 5174824 CMM_2520 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase/ siderophore binding protein YP_001223265.1 2835369 D 443906 CDS YP_001223266.1 148273705 5174280 complement(2836038..2836940) 1 NC_009480.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2836940 folD 5174280 folD Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_001223266.1 2836038 R 443906 CDS YP_001223267.1 148273706 5173583 complement(2836937..2838214) 1 NC_009480.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2838214 glyA 5173583 glyA Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine hydroxymethyltransferase YP_001223267.1 2836937 R 443906 CDS YP_001223268.1 148273707 5175553 2838511..2840157 1 NC_009480.1 putative glycosidase, possible alpha-amylase (AAM51152.1| amylosucrase Ams [Neisseria meningitidis]; ZP_00293345.1| COG0366: Glycosidases [Thermobifida fusca]). pfam00128, Alpha-amylase, Alpha amylase,catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases.; Specificity unclear; putative glycosidase 2840157 5175553 CMM_2523 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosidase YP_001223268.1 2838511 D 443906 CDS YP_001223269.1 148273708 5175458 2840198..2840698 1 NC_009480.1 hypothetical membrane protein; hypothetical protein 2840698 5175458 CMM_2524 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223269.1 2840198 D 443906 CDS YP_001223270.1 148273709 5175372 complement(2840729..2841586) 1 NC_009480.1 putative transcriptional regulator, LysR family (NP_823021.1| putative LysR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; ZP_00198639.2| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam00126, HTH_1,Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain. The structure of this domain is known and is; Specificity unclear; hypothetical protein 2841586 5175372 CMM_2525 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223270.1 2840729 R 443906 CDS YP_001223271.1 148273710 5175642 2841743..2843209 1 NC_009480.1 putative efflux MFS permease (NP_825071.1| putative integral membrane efflux protein [Streptomyces avermitilis MA-4680]; ZP_00227648.1| COG0477: permeases of the major facilitator superfamily [Kineococcus radiotolerans SRS30216]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894). 2A0121: H+ Antiporter protein. COG2814, AraJ, Arabinose efflux permease.; Specificity unclear; putative MFS permease 2843209 5175642 CMM_2526 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001223271.1 2841743 D 443906 CDS YP_001223272.1 148273711 5174461 complement(2843118..2844149) 1 NC_009480.1 putative oxidoreductase (ZP_00226289.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Kineococcus radiotolerans SRS30216]; BAB79295.1| putative oxidoreductase [Streptomyces griseus]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Specificity unclear; putative oxidoreductase 2844149 5174461 CMM_2527 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223272.1 2843118 R 443906 CDS YP_001223273.1 148273712 5174501 2844268..2844942 1 NC_009480.1 putative manganese/iron-dependent repressor (C70884 probable transcription repressor sirR - Mycobacterium tuberculosis (strain H37RV); ZP_00226601.1| COG1321: Mn-dependent transcriptional regulator [Kineococcus radiotolerans SRS30216]). smart00529, HTH_DTXR, Helix-turn-helix diphteria tox regulatory element; iron dependent repressor. pfam02742, Fe_dep_repr_C, Iron dependent repressor, metal binding and dimerisation domain. This family includes the Diphtheria toxin repressor. pfam01325,Fe_dep_repress, Iron dependent repressor, N-terminal DNA binding domain. This family includes the Diphtheria toxin repressor. DNA binding is through a helix-turn-helix motif.; Specificity unclear; hypothetical protein 2844942 sirR 5174501 sirR Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223273.1 2844268 D 443906 CDS YP_001223274.1 148273713 5175167 complement(2844964..2846214) 1 NC_009480.1 putative manganese transporter, NRAMP family (AAS20095.1| H+-stimulated manganese uptake system protein [Arthrobacter aurescens]; O05916|MNTH_MYCTU Probable manganese transport protein mntH (BRAMP)). InterPro: Natural resistance-associated macrophage protein pfam01566, Nramp, Natural resistance-associated macrophage protein.; High confidence in function and specificity; manganese transporter 2846214 mntH 5175167 mntH Clavibacter michiganensis subsp. michiganensis NCPPB 382 manganese transporter YP_001223274.1 2844964 R 443906 CDS YP_001223275.1 148273714 5175653 complement(2846343..2847263) 1 NC_009480.1 hypothetical protein (ZP_00198979.1| hypothetical protein Krad06002582 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 2847263 5175653 CMM_2530 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223275.1 2846343 R 443906 CDS YP_001223276.1 148273715 5175771 complement(2847322..2848626) 1 NC_009480.1 putative sugar MFS-permease (NP_789043.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00227340.1| COG2814: Arabinose efflux permease [Kineococcus radiotolerans SRS30216]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Specificity unclear; putative sugar MFS-permease 2848626 5175771 CMM_2531 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar MFS-permease YP_001223276.1 2847322 R 443906 CDS YP_001223277.1 148273716 5175659 2848705..2849577 1 NC_009480.1 putative formyltetrahydrofolate deformylase (ZP_00226393.1| COG0788: Formyltetrahydrofolate hydrolase [Kineococcus radiotolerans SRS30216]; ZP_00215833.1| COG0788: Formyltetrahydrofolate hydrolase [Burkholderia cepacia R18194]). InterPro: Formyltetrahydrofolate deformylase. pfam01842, ACT, ACT domain. This family of domains generally have a regulatory role. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. pfam00551,Formyl_trans_N, Formyl transferase. PurU: formyltetrahydrofolate deformylase; High confidence in function and specificity; putative formyltetrahydrofolate deformylase 2849577 purU 5175659 purU Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative formyltetrahydrofolate deformylase YP_001223277.1 2848705 D 443906 CDS YP_001223278.1 148273717 5174517 complement(2849608..2850462) 1 NC_009480.1 putative ABC-transporter, permease component (ZP_00225856.1| COG0842: ABC-type multidrug transport system, permease component [Kineococcus radiotolerans SRS30216]; NP_629116.1| putative integral membrane transport protein [Streptomyces coelicolor A3(2)]). Mtu_efflux: ABC transporter efflux protein; Specificity unclear; putative ABC-transporter, permease component 2850462 5174517 CMM_2533 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC-transporter, permease component YP_001223278.1 2849608 R 443906 CDS YP_001223279.1 148273718 5175972 complement(2850459..2851523) 1 NC_009480.1 putative ABC transporter ATP-binding protein (NP_629115.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; ZP_00198185.1| COG1131: ABC-type multidrug transport system, ATPase component [Kineococcus radiotolerans SRS30216]). pfam00005,ABC_tran, ABC transporter.; Specificity unclear; hypothetical protein 2851523 5175972 CMM_2534 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223279.1 2850459 R 443906 CDS YP_001223280.1 148273719 5174928 complement(2851656..2855336) 1 NC_009480.1 putative serine protease, peptidase family S8A (Subtilase) (T05768 subtilisin-like proteinase (EC 3.4.21.-) - Arabidopsis thaliana; T07172 subtilisin-like proteinase (EC 3.4.21.-) 2 - tomato). , pfam05922,Subtilisin_N, Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. , pfam00082,Peptidase_S8, Subtilase family. , pfam02225, PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.; Specificity unclear; serine protease 2855336 sbtB 5174928 sbtB Clavibacter michiganensis subsp. michiganensis NCPPB 382 serine protease YP_001223280.1 2851656 R 443906 CDS YP_001223281.1 148273720 5175787 complement(2855583..2859182) 1 NC_009480.1 putative subtilisin-like serine protease, peptidase family S8 (T07172 subtilisin-like proteinase (EC 3.4.21.-) 2 - tomato; T05768 subtilisin-like proteinase (EC 3.4.21.-) - Arabidopsis thaliana). pfam05922, Subtilisin_N,Subtilisin N-terminal Region. This family is found at the N-terminus of a number of subtilisins. It is cleaved prior to activation of the enzyme. pfam00082, Peptidase_S8,Subtilase family. Subtilases are a family of serine proteases. pfam02225, PA, PA domain. The PA (Protease associated) domain is found as an insert domain in diverse proteases.; Specificity unclear; subtilisin-like serine protease,peptidase family S8 2859182 sbtC 5175787 sbtC Clavibacter michiganensis subsp. michiganensis NCPPB 382 subtilisin-like serine protease,peptidase family S8 YP_001223281.1 2855583 R 443906 CDS YP_001223282.1 148273721 5174024 complement(2859432..2860646) 1 NC_009480.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 2860646 icdA 5174024 icdA Clavibacter michiganensis subsp. michiganensis NCPPB 382 isocitrate dehydrogenase YP_001223282.1 2859432 R 443906 CDS YP_001223283.1 148273722 5175765 2860890..2861333 1 NC_009480.1 putative acetyltransferase (YP_062775.1| spermidine acetyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628451.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; hypothetical protein 2861333 5175765 CMM_2538 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223283.1 2860890 D 443906 CDS YP_001223284.1 148273723 5175083 2861337..2861657 1 NC_009480.1 Region created by contig update; putative methylated DNA-protein cysteine methyltransferase 2861657 5175083 CMM_2539 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methylated DNA-protein cysteine methyltransferase YP_001223284.1 2861337 D 443906 CDS YP_001223285.1 148273724 5173728 2861712..2862218 1 NC_009480.1 hypothetical protein 2862218 5173728 CMM_2540 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223285.1 2861712 D 443906 CDS YP_001223286.1 148273725 5174219 complement(2862295..2864103) 1 NC_009480.1 putative ABC transporter, fused permease and ATP-binding protein (NP_629587.1| putative ABC transporter [Streptomyces coelicolor A3(2)]; NP_622488.1| ABC-type multidrug/protein/lipid transport system, ATPase component [Thermoanaerobacter tengcongensis]). pfam00664,ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative ABC transporter, fused permease and ATP-binding protein 2864103 5174219 CMM_2541 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, fused permease and ATP-binding protein YP_001223286.1 2862295 R 443906 CDS YP_001223287.1 148273726 5174915 complement(2864100..2865962) 1 NC_009480.1 putative ABC transporter, fused permease and ATP-binding protein (NP_629588.1| putative ABC transporter [Streptomyces coelicolor A3(2)]; CAA89862.1| ABC transporter [Bacillus subtilis]). pfam00664, ABC_membrane,ABC transporter transmembrane region. pfam00005, ABC_tran,ABC transporter.; Specificity unclear; putative ABC transporter, fused permease and ATP-binding protein 2865962 5174915 CMM_2542 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, fused permease and ATP-binding protein YP_001223287.1 2864100 R 443906 CDS YP_001223288.1 148273727 5174883 complement(2866540..2867391) 1 NC_009480.1 putative NGNG-dimethylarginine dimethylaminohydrolase (Dimethylargininase) (NP_822866.1| putative dimethylarginine dimethylaminohydrolase [Streptomyces avermitilis MA-4680]; ZP_00213107.1| COG1834: N-Dimethylarginine dimethylaminohydrolase [Burkholderia cepacia R18194]). pfam02274, Amidinotransf,Amidinotransferase.; High confidence in function and specificity; putative dimethylarginine dimethylaminohydrolase 2867391 ddaH 5174883 ddaH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dimethylarginine dimethylaminohydrolase YP_001223288.1 2866540 R 443906 CDS YP_001223289.1 148273728 5175352 complement(2873905..2875530) 1 NC_009480.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2875530 purH 5175352 purH Clavibacter michiganensis subsp. michiganensis NCPPB 382 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_001223289.1 2873905 R 443906 CDS YP_001223290.1 148273729 5175699 complement(2875527..2876126) 1 NC_009480.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2876126 purN 5175699 purN Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoribosylglycinamide formyltransferase YP_001223290.1 2875527 R 443906 CDS YP_001223291.1 148273730 5175057 complement(2876130..2877410) 1 NC_009480.1 conserved membrane protein (NP_789039.1| putative integral membrane protein [Tropheryma whipplei TW08/27]; ZP_00293807.1| hypothetical protein Tfus02000005 [Thermobifida fusca]).; hypothetical protein 2877410 5175057 CMM_2546 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223291.1 2876130 R 443906 CDS YP_001223292.1 148273731 5174829 complement(2877571..2878458) 1 NC_009480.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 2878458 sucD 5174829 sucD Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinyl-CoA synthetase subunit alpha YP_001223292.1 2877571 R 443906 CDS YP_001223293.1 148273732 5175724 complement(2878486..2879649) 1 NC_009480.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 2879649 sucC 5175724 sucC Clavibacter michiganensis subsp. michiganensis NCPPB 382 succinyl-CoA synthetase subunit beta YP_001223293.1 2878486 R 443906 CDS YP_001223294.1 148273733 5175080 2879897..2880718 1 NC_009480.1 conserved hypothetical protein (EAA63080.1| hypothetical protein AN2678.2 [Aspergillus nidulans FGSC A4]; ZP_00293575.1| COG3662: Uncharacterized protein conserved in bacteria [Thermobifida fusca]).; hypothetical protein 2880718 5175080 CMM_2549 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223294.1 2879897 D 443906 CDS YP_001223295.1 148273734 5175009 2880821..2882821 1 NC_009480.1 hypothetical protein 2882821 5175009 CMM_2550 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223295.1 2880821 D 443906 CDS YP_001223296.1 148273735 5175077 complement(2882793..2885243) 1 NC_009480.1 putative ATP-dependent DNA helicase (ZP_00227575.1| COG0210: Superfamily I DNA and RNA helicases [Kineococcus radiotolerans SRS30216]; NP_628954.1| putative ATP-dependent DNA helicase II [Streptomyces coelicolor A3(2)]). pfam00580, UvrD-helicase, UvrD/REP helicase. The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA.; Specificity unclear; ATP-dependent DNA helicase 2885243 uvrD1 5175077 uvrD1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ATP-dependent DNA helicase YP_001223296.1 2882793 R 443906 CDS YP_001223297.1 148273736 5173222 complement(2885343..2886401) 1 NC_009480.1 putative glycerophosphoryl diester phosphodiesterase (ZP_00108394.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Nostoc punctiforme]; ZP_00292545.1| COG0584: Glycerophosphoryl diester phosphodiesterase [Thermobifida fusca]). GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE HYDROLYZES DEACYLATED PHOSPHOLIPIDS TO G3P AND THE CORRESPONDING ALCOHOLS. pfam03009, GDPD, Glycerophosphoryl diester phosphodiesterase family.; High confidence in function and specificity; hypothetical protein 2886401 glpQ1 5173222 glpQ1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223297.1 2885343 R 443906 CDS YP_001223298.1 148273737 5175362 2886534..2887337 1 NC_009480.1 conserved membrane protein (ZP_00227380.1| COG4760: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; NP_627303.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam06539,DUF1112, Protein of unknown function (DUF1112).; Function unclear; hypothetical protein 2887337 5175362 CMM_2553 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223298.1 2886534 D 443906 CDS YP_001223299.1 148273738 5175014 complement(2887446..2889026) 1 NC_009480.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2889026 guaA 5175014 guaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 GMP synthase YP_001223299.1 2887446 R 443906 CDS YP_001223300.1 148273739 5174061 complement(2889023..2889565) 1 NC_009480.1 conserved membrane protein (NP_789036.1| putative membrane protein [Tropheryma whipplei TW08/27]; NP_601701.1| hypothetical membrane protein [Corynebacterium glutamicum ATCC 13032]).; Conserved hypothetical protein; hypothetical protein 2889565 5174061 CMM_2555 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223300.1 2889023 R 443906 CDS YP_001223301.1 148273740 5175837 complement(2889575..2890582) 1 NC_009480.1 conserved membrane protein (NP_789035.1| putative membrane protein [Tropheryma whipplei TW08/27]; ZP_00057673.1| COG3346: Uncharacterized conserved protein [Thermobifida fusca]).; Conserved hypothetical protein; hypothetical protein 2890582 5175837 CMM_2556 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223301.1 2889575 R 443906 CDS YP_001223302.1 148273741 5174837 complement(2890582..2892102) 1 NC_009480.1 putative Na+/H+ exchange transport protein, Cpa2 family (NP_631436.1| putative transmembrane transport protein. [Streptomyces coelicolor A3(2)]; G69819 Na+/H+ antiporter homolog yhaU - Bacillus subtilis). , InterPro: Na+/H+ exchanger pfam00999, Na_H_Exchanger,Sodium/hydrogen exchanger family. Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells.; High confidence in function and specificity; CPA2 family Na+/H+ antiporter 2892102 napA 5174837 napA Clavibacter michiganensis subsp. michiganensis NCPPB 382 CPA2 family Na+/H+ antiporter YP_001223302.1 2890582 R 443906 CDS YP_001223303.1 148273742 5174746 complement(2892106..2892639) 1 NC_009480.1 conserved hypothetical protein (ZP_00225982.1| COG0490: Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Kineococcus radiotolerans SRS30216]; CAB08338.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]). pfam02080, TrkA_C, TrkA-C domain. This domain is often found next to the pfam02254 domain.; Function unclear; hypothetical protein 2892639 5174746 CMM_2558 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223303.1 2892106 R 443906 CDS YP_001223304.1 148273743 5175838 complement(2892741..2893859) 1 NC_009480.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5-monophosphate dehydrogenase 2893859 guaB1 5175838 guaB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 inosine 5-monophosphate dehydrogenase YP_001223304.1 2892741 R 443906 CDS YP_001223305.1 148273744 5173882 complement(2893852..2894952) 1 NC_009480.1 hypothetical protein 2894952 5173882 CMM_2560 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223305.1 2893852 R 443906 CDS YP_001223306.1 148273745 5174384 complement(2895118..2896620) 1 NC_009480.1 Inosine-5-monophosphate dehydrogenase (IMP dehydrogenase) (ZP_00227592.1| COG0516: IMP dehydrogenase/GMP reductase [Kineococcus radiotolerans SRS30216]; NP_826177.1| putative inosine-5'-monophosphate dehydrogenase [Streptomyces avermitilis MA-4680]). pfam00478, IMPDH, IMP dehydrogenase / GMP reductase domain.; High confidence in function and specificity; inosine-5'-monophosphate dehydrogenase 2896620 guaB2 5174384 guaB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 inosine-5'-monophosphate dehydrogenase YP_001223306.1 2895118 R 443906 CDS YP_001223307.1 148273746 5175280 2896858..2898318 1 NC_009480.1 putative branched-chain amino acid ABC transporter,permease component (ZP_00291531.1| COG0559: Branched-chain amino acid ABC-type transport system, permease components [Thermobifida fusca]; NP_682382.1| branched-chain amino acid ABC transporter permease protein [Thermosynechococcus elongatus BP-1]). InterPro: Binding-system dependent bacterial transporters (araH livH/limM families). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; High confidence in function and specificity; branched-chain amino acid ABC transporter,permease protein 2898318 livH 5175280 livH Clavibacter michiganensis subsp. michiganensis NCPPB 382 branched-chain amino acid ABC transporter,permease protein YP_001223307.1 2896858 D 443906 CDS YP_001223308.1 148273747 5173123 2898325..2899296 1 NC_009480.1 putative branched-chain amino acid ABC transporter,permease component (ZP_00291530.1| COG4177: ABC-type branched-chain amino acid transport system, permease component [Thermobifida fusca]; ZP_00202257.1| COG4177: ABC-type branched-chain amino acid transport system,permease component [Synechococcus elongatus PCC 7942]). pfam02653, BPD_transp_2, Branched-chain amino acid transport system / permease component.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter, permease component 2899296 livM 5173123 livM Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative branched-chain amino acid ABC transporter, permease component YP_001223308.1 2898325 D 443906 CDS YP_001223309.1 148273748 5173705 2899289..2900212 1 NC_009480.1 putatice branched-chain amino acid ABC transporter,ATPase component (ZP_00291529.1| COG0411: ABC-type branched-chain amino acid transport systems, ATPase component [Thermobifida fusca]; ZP_00202256.1| COG0411: ABC-type branched-chain amino acid transport systems,ATPase component [Synechococcus elongatus PCC 7942]). pfam00005, ABC_tran, ABC transporter.; High confidence in function and specificity; putatice branched-chain amino acid ABC transporter, ATPase component 2900212 livG 5173705 livG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putatice branched-chain amino acid ABC transporter, ATPase component YP_001223309.1 2899289 D 443906 CDS YP_001223310.1 148273749 5174603 2900209..2900967 1 NC_009480.1 putative branched-chain amino acid ABC transporter,ATPase component (ZP_00291528.1| COG0410: ABC-type branched-chain amino acid transport systems, ATPase component [Thermobifida fusca]; NP_680844.1| branched-chain amino acid ABC transporter ATP-binding protein [Thermosynechococcus elongatus BP-1]). pfam00005,ABC_tran, ABC transporter.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter, ATPase component 2900967 livF 5174603 livF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative branched-chain amino acid ABC transporter, ATPase component YP_001223310.1 2900209 D 443906 CDS YP_001223311.1 148273750 5174891 complement(2901299..2902582) 1 NC_009480.1 putative branched-chain amino acid ABC transporter,substrate-binding protein (ZP_00291710.1| COG0683: ABC-type branched-chain amino acid transport systems,periplasmic component [Thermobifida fusca]; ZP_00164894.2| COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component [Synechococcus elongatus PCC 7942]). pfam01094, ANF_receptor, Receptor family ligand binding region. This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.; High confidence in function and specificity; putative branched-chain amino acid ABC transporter, substrate-binding protein 2902582 livK 5174891 livK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative branched-chain amino acid ABC transporter, substrate-binding protein YP_001223311.1 2901299 R 443906 CDS YP_001223312.1 148273751 5174794 complement(2902761..2903714) 1 NC_009480.1 putative permease, DMT family (NP_826050.1| hypothetical protein SAV4873 [Streptomyces avermitilis MA-4680]; AAQ73536.1| RarD [Streptomyces exfoliatus]). InterPro: RarD protein; Specificity unclear; permease DMT family 2903714 5174794 CMM_2567 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease DMT family YP_001223312.1 2902761 R 443906 CDS YP_001223313.1 148273752 5174878 complement(2903875..2904171) 1 NC_009480.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 2904171 groES 5174878 groES Clavibacter michiganensis subsp. michiganensis NCPPB 382 co-chaperonin GroES YP_001223313.1 2903875 R 443906 CDS YP_001223314.1 148273753 5174628 2904316..2905518 1 NC_009480.1 putative SAM-dependant methyltransferase (ZP_00190966.2| COG0500: SAM-dependent methyltransferases [Kineococcus radiotolerans SRS30216]; NP_628916.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]; ZP_00058035.1| COG0500: SAM-dependent methyltransferases [Thermobifida fusca]).; Function unclear; putative SAM-dependant methyltransferase 2905518 5174628 CMM_2569 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative SAM-dependant methyltransferase YP_001223314.1 2904316 D 443906 CDS YP_001223315.1 148273754 5174856 complement(2905604..2906029) 1 NC_009480.1 conserved membrane protein (YP_062810.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629794.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; NP_390387.1| yqfX [Bacillus subtilis]).; Function unclear; hypothetical protein 2906029 5174856 CMM_2570 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223315.1 2905604 R 443906 CDS YP_001223316.1 148273755 5173835 complement(2906134..2907753) 1 NC_009480.1 putative acetyltransferase/glycoprotease fusion protein (NP_826151.1| putative glycoprotease [Streptomyces avermitilis MA-4680]; NP_628910.1| putative O-sialoglycoprotein endopeptidase [Streptomyces coelicolor A3(2)]). apparently a fusion protein with a C-terminal peptidase domain: InterPro: Glycoprotease (M22) metallo-protease family pfam00814, Peptidase_M22, Glycoprotease family. and a N-terminal acetyltransferase domain: COG0456, RimI, Acetyltransferases [General function prediction only] pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase/glycoprotease fusion protein 2907753 5173835 CMM_2571 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase/glycoprotease fusion protein YP_001223316.1 2906134 R 443906 CDS YP_001223317.1 148273756 5175048 complement(2907750..2908367) 1 NC_009480.1 conserved hypothetical protein (YP_062813.1| hypothetical protein Lxx19930 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00058039.1| COG1214: Inactive homolog of metal-dependent proteases, putative molecular chaperone [Thermobifida fusca]; NP_628908.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)]). pfam00814,Peptidase_M22, Glycoprotease family.; hypothetical protein 2908367 5175048 CMM_2572 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223317.1 2907750 R 443906 CDS YP_001223318.1 148273757 5174730 complement(2908377..2910077) 1 NC_009480.1 putative alanine racemase (YP_062001.1| alanine racemase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826144.1| putative alanine racemase [Streptomyces avermitilis MA-4680]; ZP_00058041.1| COG0787: Alanine racemase [Thermobifida fusca]). fusion protein; N-terminal alanine racemase domain: pfam01168, Ala_racemase_N,Alanine racemase, N-terminal domain + pfam00842,Ala_racemase_C, Alanine racemase, C-terminal domain. and C-terminal ATPase domain: COG0802, COG0802, Predicted ATPase or kinase [General function prediction only], pfam02367,UPF0079, Uncharacterised P-loop hydrolase UPF0079. This uncharacterised family contains a P-loop.; Specificity unclear; putative alanine racemase 2910077 alrA2 5174730 alrA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alanine racemase YP_001223318.1 2908377 R 443906 CDS YP_001223319.1 148273758 5174795 complement(2910074..2911231) 1 NC_009480.1 putative alanine racemase (YP_062815.1| alanine racemase [Leifsonia xyli subsp. xyli str. CTCB07]; CAB01033.1| ALANINE RACEMASE ALR [Mycobacterium tuberculosis H37Rv]; ZP_00058041.1| COG0787: Alanine racemase [Thermobifida fusca]). pfam01168, Ala_racemase_N,Alanine racemase, N-terminal domain. pfam00842,Ala_racemase_C, Alanine racemase, C-terminal domain. InterPro: Alanine racemase.; High confidence in function and specificity; putative alanine racemase 2911231 alrA1 5174795 alrA1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative alanine racemase YP_001223319.1 2910074 R 443906 CDS YP_001223320.1 148273759 5173026 complement(2911228..2911587) 1 NC_009480.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2911587 acpS 5173026 acpS Clavibacter michiganensis subsp. michiganensis NCPPB 382 4'-phosphopantetheinyl transferase YP_001223320.1 2911228 R 443906 CDS YP_001223321.1 148273760 5175318 complement(2911598..2913448) 1 NC_009480.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 2913448 glmS 5175318 glmS Clavibacter michiganensis subsp. michiganensis NCPPB 382 glucosamine--fructose-6-phosphate aminotransferase YP_001223321.1 2911598 R 443906 CDS YP_001223322.1 148273761 5173153 2913597..2914556 1 NC_009480.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2914556 coaA 5173153 coaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 pantothenate kinase YP_001223322.1 2913597 D 443906 CDS YP_001223323.1 148273762 5174761 complement(2914590..2915903) 1 NC_009480.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 2915903 glmM 5174761 glmM Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglucosamine mutase YP_001223323.1 2914590 R 443906 CDS YP_001223324.1 148273763 5174838 complement(2915927..2916412) 1 NC_009480.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2916412 rpsI 5174838 rpsI Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S9 YP_001223324.1 2915927 R 443906 CDS YP_001223325.1 148273764 5174726 complement(2916463..2916909) 1 NC_009480.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2916909 rplM 5174726 rplM Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L13 YP_001223325.1 2916463 R 443906 CDS YP_001223326.1 148273765 5175287 complement(2917061..2918065) 1 NC_009480.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2918065 truA 5175287 truA Clavibacter michiganensis subsp. michiganensis NCPPB 382 tRNA pseudouridine synthase A YP_001223326.1 2917061 R 443906 CDS YP_001223327.1 148273766 5175650 complement(2918062..2919132) 1 NC_009480.1 conserved hypothetical protein, putative acetyltransferase (CAF21237.1| GCN5-related N-acetyltransferase [Corynebacterium glutamicum ATCC 13032]; NP_628328.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 2919132 5175650 CMM_2582 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223327.1 2918062 R 443906 CDS YP_001223328.1 148273767 5175354 complement(2919257..2919820) 1 NC_009480.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2919820 rplQ 5175354 rplQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L17 YP_001223328.1 2919257 R 443906 CDS YP_001223329.1 148273768 5173499 complement(2919873..2920868) 1 NC_009480.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2920868 rpoA 5173499 rpoA Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA-directed RNA polymerase subunit alpha YP_001223329.1 2919873 R 443906 CDS YP_001223330.1 148273769 5174340 complement(2921030..2921428) 1 NC_009480.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2921428 rpsK 5174340 rpsK Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S11 YP_001223330.1 2921030 R 443906 CDS YP_001223331.1 148273770 5173081 complement(2921473..2921847) 1 NC_009480.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2921847 rpsM 5173081 rpsM Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S13 YP_001223331.1 2921473 R 443906 CDS YP_001223332.1 148273771 5175361 complement(2922001..2922114) 1 NC_009480.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2922114 rpmJ 5175361 rpmJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L36 YP_001223332.1 2922001 R 443906 CDS YP_001223333.1 148273772 5174797 complement(2922187..2922408) 1 NC_009480.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2922408 infA 5174797 infA Clavibacter michiganensis subsp. michiganensis NCPPB 382 translation initiation factor IF-1 YP_001223333.1 2922187 R 443906 CDS YP_001223334.1 148273773 5175980 complement(2922650..2923819) 1 NC_009480.1 putative mannitol-1-phosphate 5-dehydrogenase (YP_061273.1| mannitol-1-phosphate 5-dehydrogenase [Leifsonia xyli subsp. xyli str. CTCB07]; AAL89587.1| mannitol-1-phosphate dehydrogenase [Aspergillus niger]). pfam01232, Mannitol_dh, Mannitol dehydrogenase.; High confidence in function and specificity; mannitol-1-phosphate 5-dehydrogenase 2923819 mtlD 5175980 mtlD Clavibacter michiganensis subsp. michiganensis NCPPB 382 mannitol-1-phosphate 5-dehydrogenase YP_001223334.1 2922650 R 443906 CDS YP_001223335.1 148273774 5174224 complement(2923816..2924253) 1 NC_009480.1 putative PTS system mannitol-specific IIA component (Mannitol- permease IIA component) (YP_061274.1| PTS system, mannitol-specific enzyme II, A component [Leifsonia xyli subsp. xyli str. CTCB07]; NP_244719.1| PTS system, mannitol-specific enzyme II, A component [Bacillus halodurans C-125]). pfam00359, PTS_EIIA_2,Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.; Specificity unclear; putative PTS system mannitol-specific IIA component 2924253 mtlF 5174224 mtlF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative PTS system mannitol-specific IIA component YP_001223335.1 2923816 R 443906 CDS YP_001223336.1 148273775 5174667 complement(2924361..2925890) 1 NC_009480.1 putative PTS system mannitol-specific IIBC component (Mannitol- permease IIBC component) (YP_061275.1| PTS system, mannitol-specific IIBC component [Leifsonia xyli subsp. xyli str. CTCB07]; YP_090154.1| MtlA [Bacillus licheniformis DSM 13]). pfam02378,PTS_EIIC, Phosphotransferase system, EIIC. pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; putative PTS system mannitol-specific IIBC component 2925890 mtlA 5174667 mtlA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative PTS system mannitol-specific IIBC component YP_001223336.1 2924361 R 443906 CDS YP_001223337.1 148273776 5174038 complement(2926003..2927673) 1 NC_009480.1 phosphoenolpyruvate-protein phosphotransferase, PTS enzyme I (YP_061276.1| PTS system, enzyme I [Leifsonia xyli subsp. xyli str. CTCB07]; NP_828150.1| putative phosphoenolpyruvate-protein phosphotransferase [Streptomyces avermitilis MA-4680]). pfam05524, PEP-utilisers_N, PEP-utilising enzyme, N-terminal. pfam02896,PEP-utilizers_C, PEP-utilising enzyme, TIM barrel domain. pfam00391, PEP-utilizers, PEP-utilising enzyme, mobile domain. InterPro: PEP-utilizing enzyme.; Specificity unclear; phosphoenolpyruvate-protein phosphotransferase,PTS enzyme I 2927673 5174038 CMM_2592 Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoenolpyruvate-protein phosphotransferase,PTS enzyme I YP_001223337.1 2926003 R 443906 CDS YP_001223338.1 148273777 5173888 complement(2927670..2927936) 1 NC_009480.1 phosphotransferase system, HPr-related protein (YP_061277.1| phosphocarrier protein HPr [Leifsonia xyli subsp. xyli str. CTCB07]; NP_623408.1| Phosphotransferase system, HPr-related proteins [Thermoanaerobacter tengcongensis]). pfam00381, PTS-HPr, PTS HPr component phosphorylation site.; Specificity unclear; hypothetical protein 2927936 5173888 CMM_2593 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223338.1 2927670 R 443906 CDS YP_001223339.1 148273778 5174642 complement(2928035..2928415) 1 NC_009480.1 putative PTS system cellobiose-specific IIB component (Cellobiose- permease IIB component) (ZP_00322547.1| COG1440: Phosphotransferase system cellobiose-specific component IIB [Pediococcus pentosaceus ATCC 25745]; YP_061278.1| PTS system, IIB component [Leifsonia xyli subsp. xyli str. CTCB07]). pfam02302,PTS_IIB, PTS system, Lactose/Cellobiose specific IIB subunit.; Specificity unclear; putative PTS system cellobiose-specific IIB component 2928415 5174642 CMM_2594 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative PTS system cellobiose-specific IIB component YP_001223339.1 2928035 R 443906 CDS YP_001223340.1 148273779 5175825 2928627..2930615 1 NC_009480.1 putative transcription antiterminator containing a PTS domain (YP_061280.1| transcription antiterminator,BglG family [Leifsonia xyli subsp. xyli str. CTCB07]; YP_074779.1| transcription antiterminator BglG family [Symbiobacterium thermophilum IAM 14863]). pfam00874, PRD,PRD domain. The PRD domain (for PTS Regulation Domain), is the phosphorylatable regulatory domain found in bacterial transcriptional antiterminator of the BglG family as well as in activators such as MtlR and LevR. pfam00359,PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. InterPro: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.; Specificity unclear; transcription antiterminator 2930615 5175825 CMM_2595 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcription antiterminator YP_001223340.1 2928627 D 443906 CDS YP_001223341.1 148273780 5175752 complement(2930668..2931504) 1 NC_009480.1 putative methionine aminopeptidase, family M24A (Peptidase M) (YP_062833.1| methionine aminopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227085.1| COG0024: Methionine aminopeptidase [Kineococcus radiotolerans SRS30216]; NP_826125.1| putative methionine aminopeptidase [Streptomyces avermitilis MA-4680]). pfam00557, Peptidase_M24, metallopeptidase family M24. InterPro: Methionine aminopeptidase subfamily 1.; High confidence in function and specificity; putative methionine aminopeptidase 2931504 mapA2 5175752 mapA2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative methionine aminopeptidase YP_001223341.1 2930668 R 443906 CDS YP_001223342.1 148273781 5175264 complement(2931509..2932111) 1 NC_009480.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2932111 adk 5175264 adk Clavibacter michiganensis subsp. michiganensis NCPPB 382 adenylate kinase YP_001223342.1 2931509 R 443906 CDS YP_001223343.1 148273782 5173069 complement(2932108..2933430) 1 NC_009480.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2933430 secY 5173069 secY Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecY YP_001223343.1 2932108 R 443906 CDS YP_001223344.1 148273783 5173274 complement(2933556..2934134) 1 NC_009480.1 late assembly protein; 50S ribosomal protein L15 2934134 rplO 5173274 rplO Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L15 YP_001223344.1 2933556 R 443906 CDS YP_001223345.1 148273784 5173427 complement(2934134..2934316) 1 NC_009480.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2934316 rpmD 5173427 rpmD Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L30 YP_001223345.1 2934134 R 443906 CDS YP_001223346.1 148273785 5173805 complement(2934316..2934981) 1 NC_009480.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2934981 rpsE 5173805 rpsE Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S5 YP_001223346.1 2934316 R 443906 CDS YP_001223347.1 148273786 5175741 complement(2935017..2935388) 1 NC_009480.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2935388 rplR 5175741 rplR Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L18 YP_001223347.1 2935017 R 443906 CDS YP_001223348.1 148273787 5173836 complement(2935391..2935927) 1 NC_009480.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2935927 rplF 5173836 rplF Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L6 YP_001223348.1 2935391 R 443906 CDS YP_001223349.1 148273788 5173700 complement(2935932..2936330) 1 NC_009480.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2936330 rpsH 5173700 rpsH Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S8 YP_001223349.1 2935932 R 443906 CDS YP_001223350.1 148273789 5175075 complement(2936468..2937064) 1 NC_009480.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2937064 rplE 5175075 rplE Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L5 YP_001223350.1 2936468 R 443906 CDS YP_001223351.1 148273790 5174553 complement(2937067..2937426) 1 NC_009480.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2937426 rplX 5174553 rplX Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L24 YP_001223351.1 2937067 R 443906 CDS YP_001223352.1 148273791 5173571 complement(2937429..2937797) 1 NC_009480.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2937797 rplN 5173571 rplN Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L14 YP_001223352.1 2937429 R 443906 CDS YP_001223353.1 148273792 5175408 complement(2937825..2938121) 1 NC_009480.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2938121 rpsQ 5175408 rpsQ Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S17 YP_001223353.1 2937825 R 443906 CDS YP_001223354.1 148273793 5173398 complement(2938124..2938450) 1 NC_009480.1 50S ribosomal protein L29 (YP_062846.1| 50S ribosomal protein L29 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789155.1| 50s ribosomal protein L29 [Tropheryma whipplei TW08/27]). pfam00831, Ribosomal_L29,Ribosomal L29 protein. InterPro: Ribosomal protein L29.; High confidence in function and specificity; 50S ribosomal protein L29 2938450 rpmC 5173398 rpmC Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L29 YP_001223354.1 2938124 R 443906 CDS YP_001223355.1 148273794 5175071 complement(2938450..2938869) 1 NC_009480.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2938869 rplP 5175071 rplP Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L16 YP_001223355.1 2938450 R 443906 CDS YP_001223356.1 148273795 5173113 complement(2938872..2939669) 1 NC_009480.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2939669 rpsC 5173113 rpsC Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S3 YP_001223356.1 2938872 R 443906 CDS YP_001223357.1 148273796 5173009 complement(2939669..2940061) 1 NC_009480.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2940061 rplV 5173009 rplV Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L22 YP_001223357.1 2939669 R 443906 CDS YP_001223358.1 148273797 5174210 complement(2940087..2940368) 1 NC_009480.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2940368 rpsS 5174210 rpsS Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S19 YP_001223358.1 2940087 R 443906 CDS YP_001223359.1 148273798 5174211 complement(2940381..2941220) 1 NC_009480.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2941220 rplB 5174211 rplB Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L2 YP_001223359.1 2940381 R 443906 CDS YP_001223360.1 148273799 5173292 complement(2941243..2941542) 1 NC_009480.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2941542 rplW 5173292 rplW Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L23 YP_001223360.1 2941243 R 443906 CDS YP_001223361.1 148273800 5174526 complement(2941539..2942195) 1 NC_009480.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2942195 rplD 5174526 rplD Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L4 YP_001223361.1 2941539 R 443906 CDS YP_001223362.1 148273801 5174925 complement(2942198..2942851) 1 NC_009480.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2942851 rplC 5174925 rplC Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L3 YP_001223362.1 2942198 R 443906 CDS YP_001223363.1 148273802 5173021 complement(2942860..2943168) 1 NC_009480.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2943168 rpsJ 5173021 rpsJ Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S10 YP_001223363.1 2942860 R 443906 CDS YP_001223364.1 148273803 5173782 complement(2943609..2944577) 1 NC_009480.1 putative topoisomerase IB (NP_962178.1| hypothetical protein MAP3244 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_119639.1| hypothetical protein nfa34270 [Nocardia farcinica IFM 10152]; ZP_00195032.2| COG3569: Topoisomerase IB [Mesorhizobium sp. BNC1]). pfam01028, Topoisom_I, Eukaryotic DNA topoisomerase I, catalytic core. Topoisomerase I promotes the relaxation of DNA superhelical tension by introducing a transient single-stranded break in duplex DNA and are vital for the processes of replication, transcription, and recombination.; Function unclear; putative topoisomerase IB 2944577 5173782 CMM_2619 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative topoisomerase IB YP_001223364.1 2943609 R 443906 CDS YP_001223365.1 148273804 5175645 complement(2944727..2945920) 1 NC_009480.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 2945920 tufA 5175645 tufA Clavibacter michiganensis subsp. michiganensis NCPPB 382 elongation factor Tu YP_001223365.1 2944727 R 443906 CDS YP_001223366.1 148273805 5175233 complement(2946034..2948148) 1 NC_009480.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 2948148 fusA 5175233 fusA Clavibacter michiganensis subsp. michiganensis NCPPB 382 elongation factor G YP_001223366.1 2946034 R 443906 CDS YP_001223367.1 148273806 5174475 complement(2948196..2948666) 1 NC_009480.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 2948666 rpsG 5174475 rpsG Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S7 YP_001223367.1 2948196 R 443906 CDS YP_001223368.1 148273807 5174347 complement(2948666..2949040) 1 NC_009480.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 2949040 rpsL 5174347 rpsL Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S12 YP_001223368.1 2948666 R 443906 CDS YP_001223369.1 148273808 5174985 complement(2949306..2949731) 1 NC_009480.1 hypothetical membrane protein (YP_062863.1| hypothetical protein Lxx20430 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2949731 5174985 CMM_2624 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223369.1 2949306 R 443906 CDS YP_001223370.1 148273809 5175094 complement(2949751..2950743) 1 NC_009480.1 hypothetical membrane protein (YP_062864.1| hypothetical protein Lxx20440 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2950743 5175094 CMM_2625 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223370.1 2949751 R 443906 CDS YP_001223371.1 148273810 5174439 complement(2950817..2951656) 1 NC_009480.1 putative polar amino acid ABC transporter, ATP-binding protein (P39456|YCKI_BACSU Probable amino-acid ABC transporter ATP-binding protein yckI; YP_088467.1| GlnQ protein [Mannheimia succiniciproducens MBEL55E]).; Specificity unclear; putative polar amino acid ABC transporter, ATP-binding protein 2951656 5174439 CMM_2626 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polar amino acid ABC transporter, ATP-binding protein YP_001223371.1 2950817 R 443906 CDS YP_001223372.1 148273811 5174875 complement(2951643..2952308) 1 NC_009480.1 putative polar amino acid ABC transporter, permease component (ZP_00235846.1| amino acid ABC transporter,permease protein [Bacillus cereus G9241]; NP_283777.1| putative amino acid permease integral membrane protein [Neisseria meningitidis Z2491]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative polar amino acid ABC transporter,permease component 2952308 5174875 CMM_2627 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polar amino acid ABC transporter,permease component YP_001223372.1 2951643 R 443906 CDS YP_001223373.1 148273812 5174540 complement(2952353..2953201) 1 NC_009480.1 putative polar amino acid ABC transporter,substrate-binding protein (ZP_00332407.1| COG0834: ABC-type amino acid transport/signal transduction systems,periplasmic component/domain [Streptococcus suis 89/1591]; NP_349917.1| Periplasmic amino acid binding protein [Clostridium acetobutylicum ATCC 824]). pfam00497,SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3. InterPro: Bacterial extracellular solute-binding proteins family 3.; Specificity unclear; putative polar amino acid ABC transporter,substrate-binding protein 2953201 5174540 CMM_2628 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polar amino acid ABC transporter,substrate-binding protein YP_001223373.1 2952353 R 443906 CDS YP_001223374.1 148273813 5174480 complement(2953410..2953895) 1 NC_009480.1 hypothetical protein 2953895 5174480 CMM_2629 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223374.1 2953410 R 443906 CDS YP_001223375.1 148273814 5174881 complement(2954078..2957977) 1 NC_009480.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 2957977 rpoC 5174881 rpoC Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA-directed RNA polymerase subunit beta' YP_001223375.1 2954078 R 443906 CDS YP_001223376.1 148273815 5174810 complement(2958026..2961514) 1 NC_009480.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 2961514 rpoB 5174810 rpoB Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA-directed RNA polymerase subunit beta YP_001223376.1 2958026 R 443906 CDS YP_001223377.1 148273816 5173071 2961820..2962488 1 NC_009480.1 putative Zn-dependant hydrolase (ZP_00291971.1| COG0491: Zn-dependent hydrolases, including glyoxylases [Thermobifida fusca]; NP_626224.1| putative hydrolase [Streptomyces coelicolor A3(2)]). pfam00753, Lactamase_B,Metallo-beta-lactamase superfamily. InterPro: Metallo-beta-lactamase superfamily.; Hypothetical protein; putative Zn-dependant hydrolase 2962488 5173071 CMM_2632 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant hydrolase YP_001223377.1 2961820 D 443906 CDS YP_001223378.1 148273817 5174451 2962541..2963398 1 NC_009480.1 conserved hypothetical protein (YP_062875.1| hypothetical protein Lxx20650 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625605.1| hypothetical protein SCO1320 [Streptomyces coelicolor A3(2)]). only weak similarity to: pfam01564, Spermine_synth, Spermine/spermidine synthase.; hypothetical protein 2963398 5174451 CMM_2633 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223378.1 2962541 D 443906 CDS YP_001223379.1 148273818 5174304 2963439..2964623 1 NC_009480.1 conserved hypothetical protein (ZP_00293383.1| COG2133: Glucose/sorbosone dehydrogenases [Thermobifida fusca]; NP_823913.1| putative oxidoreductase [Streptomyces avermitilis MA-4680]).; Function unclear; hypothetical protein 2964623 5174304 CMM_2634 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223379.1 2963439 D 443906 CDS YP_001223380.1 148273819 5173454 2964688..2965164 1 NC_009480.1 hypothetical protein (YP_062878.1| hypothetical protein Lxx20680 [Leifsonia xyli subsp. xyli str. CTCB07]; D83991 hypothetical protein BH2732 [imported] -Bacillus halodurans (strain C-125)).; hypothetical protein 2965164 5173454 CMM_2635 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223380.1 2964688 D 443906 CDS YP_001223381.1 148273820 5173096 2965201..2965713 1 NC_009480.1 conserved hypothetical protein (YP_062877.1| phage-related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00228460.2| COG3091: Uncharacterized protein conserved in bacteria [Kineococcus radiotolerans SRS30216]). weak similarity to: pfam03926, DUF335, Putative metallopeptidase (SprT family). This family of uncharacterised proteins may be zinc metallopeptidases.; hypothetical protein 2965713 5173096 CMM_2636 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223381.1 2965201 D 443906 CDS YP_001223382.1 148273821 5175274 2965710..2966387 1 NC_009480.1 conserved hypothetical protein (YP_062876.1| hypothetical protein Lxx20660 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628753.1| hypothetical protein SCO4591 [Streptomyces coelicolor A3(2)]). pfam07336, DUF1470,Protein of unknown function (DUF1470). This family consists of several hypothetical bacterial proteins of around 180 residues in length.; hypothetical protein 2966387 5175274 CMM_2637 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223382.1 2965710 D 443906 CDS YP_001223383.1 148273822 5173556 complement(2966416..2966718) 1 NC_009480.1 conserved hypothetical protein (ZP_00358905.1| COG2343: Uncharacterized protein conserved in bacteria [Chloroflexus aurantiacus]; NP_924913.1| hypothetical protein gsl1967 [Gloeobacter violaceus PCC 7421]). pfam04248, DUF427, Domain of unknown function (DUF427).; hypothetical protein 2966718 5173556 CMM_2638 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223383.1 2966416 R 443906 CDS YP_001223384.1 148273823 5175552 complement(2966832..2967422) 1 NC_009480.1 hypothetical protein (YP_062880.1| hypothetical protein Lxx20740 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 2967422 5175552 CMM_2639 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223384.1 2966832 R 443906 CDS YP_001223385.1 148273824 5174029 complement(2967406..2967906) 1 NC_009480.1 conserved hypothetical protein (Q98GR7|YW06_RHILO Hypothetical UPF0310 protein msl3206; BAA06500.1| hypothetical protein [Bacillus licheniformis]). pfam01878,DUF55, Protein of unknown function DUF55. This family of proteins have no known function.; hypothetical protein 2967906 5174029 CMM_2640 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223385.1 2967406 R 443906 CDS YP_001223386.1 148273825 5175798 2967976..2968512 1 NC_009480.1 hypothetical protein 2968512 5175798 CMM_2641 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223386.1 2967976 D 443906 CDS YP_001223387.1 148273826 5174187 complement(2968514..2969041) 1 NC_009480.1 hypothetical protein 2969041 5174187 CMM_2642 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223387.1 2968514 R 443906 CDS YP_001223388.1 148273827 5173868 2969091..2969738 1 NC_009480.1 conserved hypothetical protein (YP_062881.1| hypothetical protein Lxx20760 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00227854.1| COG3358: Uncharacterized conserved protein [Kineococcus radiotolerans SRS30216]; ZP_00117067.1| COG3358: Uncharacterized conserved protein [Cytophaga hutchinsonii]).; hypothetical protein 2969738 5173868 CMM_2643 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223388.1 2969091 D 443906 CDS YP_001223389.1 148273828 5173290 2969846..2971516 1 NC_009480.1 putative ATP-dependent helicase (NP_960415.1| hypothetical protein MAP1481c [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_062883.1| ATP-dependent RNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271,Helicase_C, Helicase conserved C-terminal domain.; Family membership; putative ATP-dependent helicase 2971516 5173290 CMM_2644 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent helicase YP_001223389.1 2969846 D 443906 CDS YP_001223390.1 148273829 5174981 2971696..2972319 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00192174.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_792961.1| transcriptional regulator, TetR family [Pseudomonas syringae pv. tomato str. DC3000]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 2972319 5174981 CMM_2645 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223390.1 2971696 D 443906 CDS YP_001223391.1 148273830 5174996 complement(2972390..2972944) 1 NC_009480.1 conserved hypothetical protein (YP_062885.1| hypothetical protein Lxx20800 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00049868.1| COG1051: ADP-ribose pyrophosphatase [Magnetospirillum magnetotacticum MS-1]). pfam00293, NUDIX, NUDIX domain.; Family membership; hypothetical protein 2972944 5174996 CMM_2646 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223391.1 2972390 R 443906 CDS YP_001223392.1 148273831 5175431 2973111..2973752 1 NC_009480.1 conserved hypothetical protein, putative phospholipase/carboxylesterase (YP_062886.1| hypothetical protein Lxx20810 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00121273.2| COG0400: Predicted esterase [Bifidobacterium longum DJO10A]). pfam02230,Abhydrolase_2, Phospholipase/Carboxylesterase. This family consists of both phospholipases and carboxylesterases with broad substrate specificity. InterPro: Phospholipase/Carboxylesterase.; Family membership; putative phospholipase/carboxylesterase 2973752 5175431 CMM_2647 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phospholipase/carboxylesterase YP_001223392.1 2973111 D 443906 CDS YP_001223393.1 148273832 5175943 2973833..2978653 1 NC_009480.1 putative ATP-dependent helicase (NP_856969.1| PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED PROTEIN) [Mycobacterium bovis AF2122/97]; NP_600075.2| Lhr-like helicase [Corynebacterium glutamicum ATCC 13032]). pfam00270, DEAD, DEAD/DEAH box helicase. pfam00271, Helicase_C, Helicase conserved C-terminal domain.; Function unclear; putative ATP-dependent helicase 2978653 5175943 CMM_2648 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ATP-dependent helicase YP_001223393.1 2973833 D 443906 CDS YP_001223394.1 148273833 5175637 2978681..2979484 1 NC_009480.1 putative endonuclease VIII/DNA glycosylase (YP_062887.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_117186.1| putative endonuclease VIII [Nocardia farcinica IFM 10152]). pfam01149,Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. pfam06831, H2TH, Formamidopyrimidine-DNA glycosylase H2TH domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA.; Function unclear; putative endonuclease VIII/DNA glycosylase 2979484 5175637 CMM_2649 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endonuclease VIII/DNA glycosylase YP_001223394.1 2978681 D 443906 CDS YP_001223395.1 148273834 5174862 complement(2979603..2981135) 1 NC_009480.1 putative cationic amino acid permease, APC family (YP_121066.1| putative transporter permease [Nocardia farcinica IFM 10152]; NP_696717.1| possible cationic amino acid transporter [Bifidobacterium longum NCC2705]). pfam00324, AA_permease, Amino acid permease.; Specificity unclear; cationic amino acid permease APC family 2981135 5174862 CMM_2650 Clavibacter michiganensis subsp. michiganensis NCPPB 382 cationic amino acid permease APC family YP_001223395.1 2979603 R 443906 CDS YP_001223396.1 148273835 5174495 2981390..2982397 1 NC_009480.1 putative RNA polymerase sigma factor, SigF-homolog (stress response/stationary phase sigma factor) (YP_116363.1| putative sigma factor [Nocardia farcinica IFM 10152]; BAC55891.1| RNA polymerase sigma factor [Streptomyces griseus subsp. griseus]). pfam04542,Sigma70_r2, Sigma-70 region 2. Region 2 of sigma-70 is the most conserved region of the entire protein. pfam04539,Sigma70_r3, Sigma-70 region 3. pfam04545, Sigma70_r4,Sigma-70, region 4. Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. InterPro: Sigma-70 factor family.; Specificity unclear; putative RNA polymerase sigma factor, SigF-homolog (stress response/stationary phase sigma factor) 2982397 sigF 5174495 sigF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNA polymerase sigma factor, SigF-homolog (stress response/stationary phase sigma factor) YP_001223396.1 2981390 D 443906 CDS YP_001223397.1 148273836 5174326 complement(2982466..2983068) 1 NC_009480.1 putative two-component system, sensor kinase/response regulator hybrid protein (NP_631472.1| conserved hypothetical protein SC6D11.19c. [Streptomyces coelicolor A3(2)]; ZP_00226918.1| COG2203: FOG: GAF domain [Kineococcus radiotolerans SRS30216]). pfam03861,ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; Family membership; putative two-component system, sensor kinase/response regulator hybrid protein 2983068 5174326 CMM_2652 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase/response regulator hybrid protein YP_001223397.1 2982466 R 443906 CDS YP_001223398.1 148273837 5175563 complement(2983279..2984091) 1 NC_009480.1 hypothetical protein 2984091 5175563 CMM_2653 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223398.1 2983279 R 443906 CDS YP_001223399.1 148273838 5173914 2984215..2984622 1 NC_009480.1 hypothetical protein (NP_894767.1| possible GRAM domain [Prochlorococcus marinus str. MIT 9313]; NP_638722.1| hypothetical protein XCC3376 [Xanthomonas campestris pv. campestris str. ATCC 33913]).; hypothetical protein 2984622 5173914 CMM_2654 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223399.1 2984215 D 443906 CDS YP_001223400.1 148273839 5173498 2984687..2984869 1 NC_009480.1 putative transcriptional regulator (NP_824532.1| hypothetical protein SAV3356 [Streptomyces avermitilis MA-4680]; ZP_00226779.1| COG1983: Putative stress-responsive transcriptional regulator [Kineococcus radiotolerans SRS30216]). pfam04024, PspC, PspC domain. This family includes Phage shock protein C (PspC) that is thought to be a transcriptional regulator.; Function unclear; putative transcriptional regulator 2984869 5173498 CMM_2655 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001223400.1 2984687 D 443906 CDS YP_001223401.1 148273840 5174655 2984985..2986892 1 NC_009480.1 putative amidase (NP_831822.1| Glutamyl-tRNA(Gln) amidotransferase subunit A [Bacillus cereus ATCC 14579]; NP_630436.1| putative secreted amidase [Streptomyces coelicolor A3(2)]). pfam01425, Amidase, Amidase.; Family membership; putative amidase 2986892 5174655 CMM_2656 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative amidase YP_001223401.1 2984985 D 443906 CDS YP_001223402.1 148273841 5174958 complement(2986913..2988430) 1 NC_009480.1 conserved hypothetical protein, putative phosphatase (NP_695256.1| hypothetical secreted protein with probable acid phosphatase domain [Bifidobacterium longum NCC2705]; YP_050157.1| putative phosphatase [Erwinia carotovora subsp. atroseptica SCRI1043]).; Family membership; putative phosphatase 2988430 5174958 CMM_2657 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001223402.1 2986913 R 443906 CDS YP_001223403.1 148273842 5173734 complement(2988519..2989901) 1 NC_009480.1 putative penicillin-binding protein (ZP_00244789.1| COG1680: Beta-lactamase class C and other penicillin binding proteins [Rubrivivax gelatinosus PM1]; ZP_00109292.1| COG1680: Beta-lactamase class C and other penicillin binding proteins [Nostoc punctiforme PCC 73102]). pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and pfam00768 D-alanyl-D-alanine carboxypeptidase.; Specificity unclear; putative penicillin-binding protein 2989901 5173734 CMM_2658 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative penicillin-binding protein YP_001223403.1 2988519 R 443906 CDS YP_001223404.1 148273843 5173160 complement(2989898..2990410) 1 NC_009480.1 putative transcriptional regulator, MarR-family (ZP_00188603.2| COG1846: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]; YP_118181.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator 2990410 5173160 CMM_2659 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223404.1 2989898 R 443906 CDS YP_001223405.1 148273844 5173675 2990469..2991677 1 NC_009480.1 putative monooxygenase (NP_641998.1| oxidoreductase [Xanthomonas axonopodis pv. citri str. 306]; NP_052574.1| oxidoreductase protein homolog Oxi [Corynebacterium glutamicum]). pfam01494, FAD_binding_3, FAD binding domain. pfam01360, Monooxygenase, Monooxygenase. This family includes diverse enzymes that utilise FAD. InterPro: Aromatic-ring hydroxylase (flavoprotein monooxygenase); Function unclear; putative monooxygenase 2991677 5173675 CMM_2660 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative monooxygenase YP_001223405.1 2990469 D 443906 CDS YP_001223406.1 148273845 5173118 2991847..2992254 1 NC_009480.1 Hypothetical protein; hypothetical protein 2992254 5173118 CMM_2661 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223406.1 2991847 D 443906 CDS YP_001223407.1 148273846 5174528 complement(2992321..2992926) 1 NC_009480.1 conserved hypothetical protein, putative nitroreductase (YP_104321.1| nitroreductase family protein [Burkholderia mallei ATCC 23344]; ZP_00310829.1| COG0778: Nitroreductase [Cytophaga hutchinsonii]). pfam00881,Nitroreductase, Nitroreductase family. Members of this family utilise FMN as a cofactor. InterPro: Nitroreductase family.; Function unclear; putative nitroreductase 2992926 5174528 CMM_2662 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nitroreductase YP_001223407.1 2992321 R 443906 CDS YP_001223408.1 148273847 5174392 complement(2993046..2994182) 1 NC_009480.1 putative oxidoreductase (P55609|Y4OX_RHISN HYPOTHETICAL 39.9 KD PROTEIN Y4OX; NP_437577.1| putative exported oxidoreductase protein [Sinorhizobium meliloti 1021]). pfam01408, GFO_IDH_MocA, Oxidoreductase family,NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C,Oxidoreductase family, C-terminal alpha/beta domain. InterPro: Oxidoreductase N-terminal.; Function unclear; putative oxidoreductase 2994182 5174392 CMM_2663 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223408.1 2993046 R 443906 CDS YP_001223409.1 148273848 5173759 complement(2994179..2994910) 1 NC_009480.1 conserved hypothetical protein (YP_061429.1| ThuA protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00354380.1| COG4813: Trehalose utilization protein [Kineococcus radiotolerans SRS30216]). pfam06283, DUF1037,Protein of unknown function (DUF1037).; Function unclear; hypothetical protein 2994910 5173759 CMM_2664 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223409.1 2994179 R 443906 CDS YP_001223410.1 148273849 5174144 2995087..2995941 1 NC_009480.1 conserved hypothetical protein (NP_870739.1| hypothetical protein RB12844 [Rhodopirellula baltica SH 1]; ZP_00316033.1| hypothetical protein Mdeg02002771 [Microbulbifer degradans 2-40]).; hypothetical protein 2995941 5174144 CMM_2665 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223410.1 2995087 D 443906 CDS YP_001223411.1 148273850 5173968 complement(2995954..2997852) 1 NC_009480.1 putative multidrug ABC transporter, fused permease and ATP-binding protein (NP_828394.1| putative ABC-transport protein [Streptomyces avermitilis MA-4680]; ZP_00294356.1| COG1132: ABC-type multidrug transport system, ATPase and permease components [Thermobifida fusca]). pfam00664, ABC_membrane, ABC transporter transmembrane region. pfam00005, ABC_tran, ABC transporter. InterPro: ABC transporter transmembrane region.; Specificity unclear; putative multidrug ABC transporter, fused permease and ATP-binding protein 2997852 5173968 CMM_2666 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug ABC transporter, fused permease and ATP-binding protein YP_001223411.1 2995954 R 443906 CDS YP_001223412.1 148273851 5175371 2998206..2999030 1 NC_009480.1 conserved hypothetical protein (NP_627919.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00310497.1| hypothetical protein Chut02000054 [Cytophaga hutchinsonii]). cd01045, Ferritin_like_AB,Ferritin-like domain found in Archaea and Bacteria (Ferritin_like_AB) is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins.; hypothetical protein 2999030 5175371 CMM_2667 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223412.1 2998206 D 443906 CDS YP_001223413.1 148273852 5174657 complement(2999145..2999423) 1 NC_009480.1 conserved membrane protein (YP_056449.1| hypothetical protein PPA1762 [Propionibacterium acnes KPA171202]; NP_879781.1| putative membrane protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein 2999423 5174657 CMM_2668 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223413.1 2999145 R 443906 CDS YP_001223414.1 148273853 5175331 2999548..3000216 1 NC_009480.1 putative two-component system response regulator (YP_004956.1| transcriptional regulatory protein [Thermus thermophilus HB27]; NP_835072.1| Two-component response regulator yhcZ [Bacillus cereus ATCC 14579]). pfam00072,Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. pfam00196, GerE,Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system response regulator 3000216 5175331 CMM_2669 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system response regulator YP_001223414.1 2999548 D 443906 CDS YP_001223415.1 148273854 5175857 complement(3000417..3001199) 1 NC_009480.1 conserved hypothetical protein, putative cell filamentation protein (NP_298946.1| cell filamentation protein [Xylella fastidiosa 9a5c]; ZP_00133651.2| COG2184: Protein involved in cell division [Haemophilus somnus 2336]). pfam02661, Fic, Fic protein family. This family consists of the Fic (filamentation induced by cAMP) protein and its relatives.; Function unclear; putative cell filamentation protein 3001199 5175857 CMM_2670 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative cell filamentation protein YP_001223415.1 3000417 R 443906 CDS YP_001223416.1 148273855 5174860 complement(3001199..3001405) 1 NC_009480.1 hypothetical protein 3001405 5174860 CMM_2671 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223416.1 3001199 R 443906 CDS YP_001223417.1 148273856 5173058 3001534..3002652 1 NC_009480.1 putative antibiotic immunity protein, peptidase family S66 (NP_827455.1| hypothetical protein SAV6279 [Streptomyces avermitilis MA-4680]; NP_694083.1| microcin immunity protein [Oceanobacillus iheyensis HTE831]).; Specificity unclear; antibiotic immunity protein peptidase family S66 protein 3002652 5173058 CMM_2672 Clavibacter michiganensis subsp. michiganensis NCPPB 382 antibiotic immunity protein peptidase family S66 protein YP_001223417.1 3001534 D 443906 CDS YP_001223418.1 148273857 5174815 3003259..3004305 1 NC_009480.1 conserved hypothetical protein (NP_931545.1| hypothetical protein [Photorhabdus luminescens subsp. laumondii TTO1]; NP_416276.2| hypothetical protein b1762 [Escherichia coli K12]).; hypothetical protein 3004305 5174815 CMM_2673 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223418.1 3003259 D 443906 CDS YP_001223419.1 148273858 5173252 complement(3004315..3005382) 1 NC_009480.1 putative glycosyl transferase (YP_119472.1| putative glycosyltransferase [Nocardia farcinica IFM 10152]; ZP_00058346.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thermobifida fusca]). pfam01075,Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase).; Function unclear; putative glycosyl transferase 3005382 5173252 CMM_2674 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001223419.1 3004315 R 443906 CDS YP_001223420.1 148273859 5174443 complement(3005450..3006115) 1 NC_009480.1 conserved membrane protein (NP_626607.1| putative membrane protein [Streptomyces coelicolor A3(2)]; NP_600078.1| hypothetical membrane-associated protein [Corynebacterium glutamicum ATCC 13032]). pfam00597, DedA,DedA family. Members of this family are not functionally characterised. These proteins contain multiple predicted transmembrane regions.; Function unclear; hypothetical protein 3006115 5174443 CMM_2675 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223420.1 3005450 R 443906 CDS YP_001223421.1 148273860 5174575 3006326..3007294 1 NC_009480.1 putative beta-lactamase type I precursor (S03167 beta-lactamase (EC 3.5.2.6) precursor - Bacillus cereus; BAD05863.1| beta-lactamase [Streptomyces albulus]). pfam00144, Beta-lactamase, Beta-lactamase. InterPro: Beta-lactamase family.; High confidence in function and specificity; putative beta-lactamase 3007294 blaC 5174575 blaC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-lactamase YP_001223421.1 3006326 D 443906 CDS YP_001223422.1 148273861 5173791 complement(3007331..3007954) 1 NC_009480.1 putative transcriptional regulator, TetR-family (YP_076084.1| TetR family transcriptional regulator [Symbiobacterium thermophilum IAM 14863]; CAA17330.1| POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) [Mycobacterium tuberculosis H37Rv]; NP_827280.1| putative TetR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00440, TetR_N,Bacterial regulatory proteins, tetR family.; Specificity unclear; TetR family transcriptional regulator 3007954 5173791 CMM_2677 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223422.1 3007331 R 443906 CDS YP_001223423.1 148273862 5175101 3008020..3008658 1 NC_009480.1 putative acetyltransferase (NP_600742.1| histone acetyltransferase HPA2 and related acetyltransferases [Corynebacterium glutamicum ATCC 13032]; CAB07039.1| PROBABLE ACETYLTRANSFERASE [Mycobacterium tuberculosis H37Rv]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions.; Function unclear; putative acetyltransferase 3008658 5175101 CMM_2678 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223423.1 3008020 D 443906 CDS YP_001223424.1 148273863 5173921 complement(3008701..3008937) 1 NC_009480.1 hypothetical protein 3008937 5173921 CMM_2679 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223424.1 3008701 R 443906 CDS YP_001223425.1 148273864 5174113 3008983..3009453 1 NC_009480.1 putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 3009453 5174113 CMM_2680 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223425.1 3008983 D 443906 CDS YP_001223426.1 148273865 5175176 3009517..3010362 1 NC_009480.1 conserved hypothetical protein, putative hydrolase (NP_737707.1| hypothetical protein CE1097 [Corynebacterium efficiens YS-314]; NP_822654.1| hypothetical protein SAV1479 [Streptomyces avermitilis MA-4680]). pfam03372,Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling.; putative hydrolase 3010362 5175176 CMM_2681 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001223426.1 3009517 D 443906 CDS YP_001223427.1 148273866 5174202 3010356..3011033 1 NC_009480.1 hypothetical membrane protein (NP_737708.1| hypothetical protein CE1098 [Corynebacterium efficiens YS-314]; ZP_00198909.1| hypothetical protein Krad07002970 [Kineococcus radiotolerans SRS30216]).; hypothetical protein 3011033 5174202 CMM_2682 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223427.1 3010356 D 443906 CDS YP_001223428.1 148273867 5174363 3011123..3012706 1 NC_009480.1 putative bifunctional phosphatase/glycosyl transferase (N-terminal: COG0241, HisB, Histidinol phosphatase and related phosphatases; pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase.; ZP_00056621.1| COG0241: Histidinol phosphatase and related phosphatases [Magnetospirillum magnetotacticum] C-terminal: COG0859, RfaF, ADP-heptose:LPS heptosyltransferase, pfam01075, Glyco_transf_9,Glycosyltransferase family 9 (heptosyltransferase); NP_630286.1| putative transferase [Streptomyces coelicolor A3(2)]; ZP_00058348.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thermobifida fusca]). two domain protein. N-terminal: COG0241, HisB, Histidinol phosphatase and related phosphatases; pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. C-terminal: InterPro: Glycosyltransferase family 9; pfam01075, Glyco_transf_9,Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.; Function unclear; putative bifunctional phosphatase/glycosyl transferase 3012706 5174363 CMM_2683 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bifunctional phosphatase/glycosyl transferase YP_001223428.1 3011123 D 443906 CDS YP_001223429.1 148273868 5174466 3012715..3013755 1 NC_009480.1 putative glycosyl transferase (YP_118607.1| hypothetical protein nfa23960 [Nocardia farcinica IFM 10152]; NP_962179.1| hypothetical protein MAP3245 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_630287.1| putative transferase [Streptomyces coelicolor A3(2)]). pfam00534, Glycos_transf_1, Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase 3013755 5174466 CMM_2684 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001223429.1 3012715 D 443906 CDS YP_001223430.1 148273869 5174777 3013752..3015701 1 NC_009480.1 putative bifunctional glycosyl transferase/isomerase 3015701 5174777 CMM_2685 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bifunctional glycosyl transferase/isomerase YP_001223430.1 3013752 D 443906 CDS YP_001223431.1 148273870 5174076 3015698..3017101 1 NC_009480.1 putative bifunctional ADP-heptose synthase/transferase (NP_630290.1| putative bifunctional synthase/transferase [Streptomyces coelicolor A3(2)]; NP_962186.1| hypothetical protein MAP3252 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00294, PfkB,pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases. pfam01467,CTP_transf_2, Cytidylyltransferase. InterPro: PfkB family of carbohydrate kinases.; Specificity unclear; putative bifunctional ADP-heptose synthase/transferase 3017101 5174076 CMM_2686 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bifunctional ADP-heptose synthase/transferase YP_001223431.1 3015698 D 443906 CDS YP_001223432.1 148273871 5174530 3017174..3017878 1 NC_009480.1 putative short-chain dehydrogenase/oxidoreductase (NP_962187.1| hypothetical protein MAP3253 [Mycobacterium avium subsp. paratuberculosis str. k10]; YP_118608.1| putative short chain dehydrogenase [Nocardia farcinica IFM 10152]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase 3017878 5174530 CMM_2687 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain dehydrogenase/oxidoreductase YP_001223432.1 3017174 D 443906 CDS YP_001223433.1 148273872 5175842 complement(3018382..3019062) 1 NC_009480.1 putative acetyl xylan esterase (XP_330314.1| hypothetical protein [Neurospora crassa]; AAC39371.1| acetyl xylan esterase II precursor [Penicillium purpurogenum]). , pfam01083, Cutinase, Cutinase.; Conserved hypothetical protein; hypothetical protein 3019062 5175842 CMM_2688 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223433.1 3018382 R 443906 CDS YP_001223434.1 148273873 5174257 complement(3019687..3020064) 1 NC_009480.1 Hypothetical protein; hypothetical protein 3020064 5174257 CMM_2689 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223434.1 3019687 R 443906 CDS YP_001223435.1 148273874 5174359 complement(3020157..3020768) 1 NC_009480.1 hypothetical protein (NP_103310.1| hypothetical protein mll1813 [Mesorhizobium loti MAFF303099]).; hypothetical protein 3020768 5174359 CMM_2690 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223435.1 3020157 R 443906 CDS YP_001223436.1 148273875 5175104 3020952..3021953 1 NC_009480.1 putative endoglucanase (NP_436984.1| putative cellulase H precursor protein [Sinorhizobium meliloti 1021]; P16218|GUNH_CLOTM Endoglucanase H precursor (EGH) (Endo-1,4-beta-glucanase)(Cellulase H)). weak similarity to: pfam02156, Glyco_hydro_26, Glycosyl hydrolase family 26.; Specificity unclear; putative endoglucanase 3021953 5175104 CMM_2691 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endoglucanase YP_001223436.1 3020952 D 443906 CDS YP_001223437.1 148273876 5173738 3022066..3023475 1 NC_009480.1 putative endoglucanase (P16218|GUNH_CLOTM Endoglucanase H precursor (EGH) (Endo-1,4-beta-glucanase)(Cellulase H); ZP_00329205.1| COG4124: Beta-mannanase [Moorella thermoacetica ATCC 39073]). , weak similarity to: pfam02156, Glyco_hydro_26, Glycosyl hydrolase family 26.; Specificity unclear; putative endoglucanase 3023475 5173738 CMM_2692 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative endoglucanase YP_001223437.1 3022066 D 443906 CDS YP_001223438.1 148273877 5174556 3023600..3024913 1 NC_009480.1 conserved hypothetical protein (YP_062996.1| hypothetical protein Lxx22070 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_627950.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 3024913 5174556 CMM_2693 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223438.1 3023600 D 443906 CDS YP_001223439.1 148273878 5173930 3025105..3026142 1 NC_009480.1 conserved hypothetical protein (NP_948299.1| putative DNA-binding protein [Rhodopseudomonas palustris CGA009]; YP_081386.1| Hypothetical Virulence protein RhuM [Bacillus licheniformis DSM 13]).; Family membership; hypothetical protein 3026142 5173930 CMM_2694 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223439.1 3025105 D 443906 CDS YP_001223440.1 148273879 5175019 complement(3026264..3027400) 1 NC_009480.1 putative heptosyltransferase (YP_118610.1| putative glycosyltransferase [Nocardia farcinica IFM 10152]; ZP_00333863.1| COG0859: ADP-heptose:LPS heptosyltransferase [Thiobacillus denitrificans ATCC 25259]). pfam01075, Glyco_transf_9, Glycosyltransferase family 9 (heptosyltransferase).; Function unclear; hypothetical protein 3027400 5175019 CMM_2695 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223440.1 3026264 R 443906 CDS YP_001223441.1 148273880 5175861 complement(3027486..3028577) 1 NC_009480.1 putative transcriptional regulator, LacI family (NP_631460.1| putative LacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; NP_696340.1| probable LacI-type transcriptional regulator [Bifidobacterium longum NCC2705]). pfam00356, LacI,Bacterial regulatory proteins, lacI family. pfam00532,Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; hypothetical protein 3028577 5175861 CMM_2696 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223441.1 3027486 R 443906 CDS YP_001223442.1 148273881 5175847 3028654..3029595 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_822205.1| putative binding-protein dependent transport protein [Streptomyces avermitilis MA-4680]; ZP_00121010.2| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 3029595 5175847 CMM_2697 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223442.1 3028654 D 443906 CDS YP_001223443.1 148273882 5175567 3029598..3030548 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_631458.1| putative binding-protein dependent transport protein. [Streptomyces coelicolor A3(2)]; NP_696338.1| probable permease of ABC transporter system for sugars [Bifidobacterium longum NCC2705]). pfam00528,BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 3030548 5175567 CMM_2698 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223443.1 3029598 D 443906 CDS YP_001223444.1 148273883 5175270 3030610..3031965 1 NC_009480.1 putative sugar ABC transporter, substrate-binding protein (NP_631457.1| probable solute-binding lipoprotein. [Streptomyces coelicolor A3(2)]; ZP_00121005.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]). pfam01547, SBP_bac_1,Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1; Specificity unclear; putative sugar ABC transporter, substrate-binding protein 3031965 5175270 CMM_2699 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate-binding protein YP_001223444.1 3030610 D 443906 CDS YP_001223445.1 148273884 5173608 3032047..3033846 1 NC_009480.1 putative beta-galactosidase (BAA21669.1| beta-galactosidase [Bacillus circulans]; AAC45218.1| beta-galactosidase [Arthrobacter sp.]). pfam01301,Glyco_hydro_35, Glycosyl hydrolases family 35.; Specificity unclear; putative beta-galactosidase 3033846 bgaB 5173608 bgaB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative beta-galactosidase YP_001223445.1 3032047 D 443906 CDS YP_001223446.1 148273885 5172925 3033952..3035502 1 NC_009480.1 putative aldehyde dehydrogenase (YP_120727.1| putative aldehyde dehydrogenase [Nocardia farcinica IFM 10152]; NP_828335.1| putative succinate-semialdehyde dehydrogenase [Streptomyces avermitilis MA-4680]). pfam00171, Aldedh, Aldehyde dehydrogenase family.; Function unclear; hypothetical protein 3035502 5172925 CMM_2701 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223446.1 3033952 D 443906 CDS YP_001223447.1 148273886 5174675 3035499..3037055 1 NC_009480.1 putative bifunctional sugar kinase/nucleotidyltransferase (P_118622.1| hypothetical protein nfa24110 [Nocardia farcinica IFM 10152]; ZP_00299509.1| COG2870: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Geobacter metallireducens GS-15]). pfam00294, PfkB, pfkB family carbohydrate kinase. pfam01467, CTP_transf_2,Cytidylyltransferase. InterPro: PfkB family of carbohydrate kinases.; Specificity unclear; putative bifunctional sugar kinase/nucleotidyltransferase 3037055 5174675 CMM_2702 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bifunctional sugar kinase/nucleotidyltransferase YP_001223447.1 3035499 D 443906 CDS YP_001223448.1 148273887 5175543 3037145..3037336 1 NC_009480.1 hypothetical protein (YP_118623.1| hypothetical protein nfa24120 [Nocardia farcinica IFM 10152]; NP_487423.1| unknown protein [Nostoc sp. PCC 7120]).; hypothetical protein 3037336 5175543 CMM_2703 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223448.1 3037145 D 443906 CDS YP_001223449.1 148273888 5173273 complement(3037437..3037766) 1 NC_009480.1 hypothetical protein 3037766 5173273 CMM_2704 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223449.1 3037437 R 443906 CDS YP_001223450.1 148273889 5174469 3038021..3038533 1 NC_009480.1 conserved hypothetical protein (ZP_00332567.1| COG3860: Uncharacterized protein conserved in bacteria [Streptococcus suis 89/1591]; NP_972365.1| hypothetical protein TDE1761 [Treponema denticola ATCC 35405]; NP_626931.1| putative secreted protein [Streptomyces coelicolor A3(2)]).; hypothetical protein 3038533 5174469 CMM_2705 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223450.1 3038021 D 443906 CDS YP_001223451.1 148273890 5173417 complement(3038530..3039546) 1 NC_009480.1 conserved hypothetical protein (only weak similarities: AAP74077.1| hypothetical protein PBD2.192 [Rhodococcus erythropolis]; NP_960710.1| hypothetical protein MAP1776c [Mycobacterium avium subsp. paratuberculosis str. k10]).; hypothetical protein 3039546 5173417 CMM_2706 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223451.1 3038530 R 443906 CDS YP_001223452.1 148273891 5174241 complement(3039550..3040071) 1 NC_009480.1 hypothetical protein 3040071 5174241 CMM_2707 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223452.1 3039550 R 443906 CDS YP_001223453.1 148273892 5173283 complement(3040244..3040732) 1 NC_009480.1 hypothetical protein, putative excisionase (NP_938638.1| Putative excisionase [Corynebacterium diphtheriae NCTC 13129]; AAF76245.1| putative excisionase [Arthrobacter sp. TM1]).; hypothetical protein 3040732 5173283 CMM_2708 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223453.1 3040244 R 443906 CDS YP_001223454.1 148273893 5175411 complement(3040792..3041967) 1 NC_009480.1 putative metallopeptidase, family M23 (AAS20161.1| hypothetical protein [Arthrobacter aurescens]; CAD47991.1| hypothetical protein [Arthrobacter nicotinovorans]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Function unclear; M23 family metallopeptidase 3041967 5175411 CMM_2709 Clavibacter michiganensis subsp. michiganensis NCPPB 382 M23 family metallopeptidase YP_001223454.1 3040792 R 443906 CDS YP_001223455.1 148273894 5174246 complement(3041964..3042524) 1 NC_009480.1 hypothetical protein (CAD47990.1| hypothetical protein [Arthrobacter nicotinovorans]; CAD47990.1| hypothetical protein [Arthrobacter nicotinovorans]).; hypothetical protein 3042524 5174246 CMM_2710 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223455.1 3041964 R 443906 CDS YP_001223456.1 148273895 5172924 complement(3042524..3043921) 1 NC_009480.1 hypothetical protein (CAD47989.1| hypothetical protein [Arthrobacter nicotinovorans]; YP_117040.1| hypothetical protein nfa8310 [Nocardia farcinica IFM 10152]; ZP_00058679.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]).; Family membership; hypothetical protein 3043921 5172924 CMM_2711 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223456.1 3042524 R 443906 CDS YP_001223457.1 148273896 5173117 3044186..3044797 1 NC_009480.1 hypothetical protein (CAD47988.1| hypothetical protein [Arthrobacter nicotinovorans]; NP_862425.1| MC47 [Micrococcus sp. 28]; NP_826047.1| hypothetical protein SAV4870 [Streptomyces avermitilis MA-4680]).; hypothetical protein 3044797 5173117 CMM_2712 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223457.1 3044186 D 443906 CDS YP_001223458.1 148273897 5175750 3044822..3045145 1 NC_009480.1 Hypothetical protein; hypothetical protein 3045145 5175750 CMM_2713 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223458.1 3044822 D 443906 CDS YP_001223459.1 148273898 5174683 3045207..3045968 1 NC_009480.1 conserved hypothetical protein (CAD47986.1| hypothetical protein [Arthrobacter nicotinovorans]; NP_954834.1| hypothetical protein [Gordonia westfalica]).; hypothetical protein 3045968 5174683 CMM_2714 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223459.1 3045207 D 443906 CDS YP_001223460.1 148273899 5174239 3045970..3047523 1 NC_009480.1 conserved hypothetical protein, weak similarities to congugal transfer proteins like TrbL (CAD47985.1| putative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]; NP_066793.1| transfer gene complex protein-like protein [Rhodococcus equi]). weak similarity to:pfam04610, TrbL, TrbL/VirB6 plasmid conjugal transfer protein, and COG3846, TrbL, Type IV secretory pathway, TrbL components [Intracellular trafficking and secretion]; hypothetical protein 3047523 5174239 CMM_2715 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223460.1 3045970 D 443906 CDS YP_001223461.1 148273900 5174281 3047536..3049044 1 NC_009480.1 conserved membrane protein (CAD47984.1| putative integral membrane protein [Arthrobacter nicotinovorans]; NP_696643.1| narrowly conserved hypothetical protein [Bifidobacterium longum NCC2705]).; hypothetical protein 3049044 5174281 CMM_2716 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223461.1 3047536 D 443906 CDS YP_001223462.1 148273901 5174204 3049099..3050808 1 NC_009480.1 putative ATP-binding protein (CAD47983.1| putative ATP-binding protein [Arthrobacter nicotinovorans]; NP_862419.1| putative ATP-binding protein [Micrococcus sp. 28]).; hypothetical protein 3050808 5174204 CMM_2717 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223462.1 3049099 D 443906 CDS YP_001223463.1 148273902 5175229 3050805..3052583 1 NC_009480.1 putative congujal transfer protein, coupling protein (traG/VirB4) homolog (CAD47982.1| putative conjugative transfer gene complex protein-like protein [Arthrobacter nicotinovorans]; NP_825686.1| putative traG-family protein [Streptomyces avermitilis MA-4680]). InterPro: TraG protein pfam02534, TRAG, TraG/TraD family. The TraG/TraD family are bacterial conjugation proteins.; Specificity unclear; putative traG-family protein 3052583 5175229 CMM_2718 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative traG-family protein YP_001223463.1 3050805 D 443906 CDS YP_001223464.1 148273903 5174703 3052580..3052966 1 NC_009480.1 hypothetical protein (CAD47981.1| hypothetical protein [Arthrobacter nicotinovorans]; ZP_00058175.1| hypothetical protein [Thermobifida fusca]).; hypothetical protein 3052966 5174703 CMM_2719 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223464.1 3052580 D 443906 CDS YP_001223465.1 148273904 5175851 3052963..3053808 1 NC_009480.1 Hypothetical protein; hypothetical protein 3053808 5175851 CMM_2720 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223465.1 3052963 D 443906 CDS YP_001223466.1 148273905 5175824 complement(3053831..3055084) 1 NC_009480.1 Region start changed from 3055087 to 3055030 (-57 bases); putative protein phosphatase 3055084 5175824 CMM_2721 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein phosphatase YP_001223466.1 3053831 R 443906 CDS YP_001223467.1 148273906 5175891 complement(3055238..3056566) 1 NC_009480.1 putative serine phosphatase, possible regulator of sigma factor activity (ZP_00175659.2| COG2208: Serine phosphatase RsbU, regulator of sigma subunit [Crocosphaera watsonii WH 8501]; NP_874405.1| Serine phosphatase RsbU [Prochlorococcus marinus subsp. marinus str. CCMP1375]). InterPro: Protein phosphatase 2C domain smart00331,PP2C_SIG, Sigma factor PP2C-like phosphatases; Function unclear; putative serine phosphatase 3056566 5175891 CMM_2722 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative serine phosphatase YP_001223467.1 3055238 R 443906 CDS YP_001223468.1 148273907 5175067 complement(3056566..3056988) 1 NC_009480.1 conserved hypothetical protein, putative anti-sigma regulatory factor (NP_737815.1| hypothetical protein [Corynebacterium efficiens YS-314]; NP_681341.1| sigma-B activity negative regulator [Thermosynechococcus elongatus BP-1]).; Function unclear; hypothetical protein 3056988 5175067 CMM_2723 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223468.1 3056566 R 443906 CDS YP_001223469.1 148273908 5175597 complement(3056981..3057319) 1 NC_009480.1 putative anti-sigma factor antagonist (NP_737814.1| putative anti-sigma factor antagonist [Corynebacterium efficiens YS-314]; ZP_00357937.1| COG1366: Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [Chloroflexus aurantiacus]). pfam01740, STAS, STAS domain.; Function unclear; hypothetical protein 3057319 5175597 CMM_2724 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223469.1 3056981 R 443906 CDS YP_001223470.1 148273909 5175011 3057585..3057953 1 NC_009480.1 hypothetical protein 3057953 5175011 CMM_2725 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223470.1 3057585 D 443906 CDS YP_001223471.1 148273910 5174681 complement(3057950..3058576) 1 NC_009480.1 putative phosphoglycerate mutase (NP_822948.1| putative mutase [Streptomyces avermitilis MA-4680]; NP_349622.1| Possible phosphoglycerate mutase [Clostridium acetobutylicum ATCC 824]). pfam00300, PGAM,Phosphoglycerate mutase family.; High confidence in function and specificity; phosphoglycerate mutase 3058576 5174681 CMM_2726 Clavibacter michiganensis subsp. michiganensis NCPPB 382 phosphoglycerate mutase YP_001223471.1 3057950 R 443906 CDS YP_001223472.1 148273911 5174947 3058730..3059692 1 NC_009480.1 Hypothetical protein; hypothetical protein 3059692 5174947 CMM_2727 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223472.1 3058730 D 443906 CDS YP_001223473.1 148273912 5174508 complement(3059727..3060149) 1 NC_009480.1 putative acetyltransferase (ZP_00036563.1| COG0454: Histone acetyltransferase HPA2 and related acetyltransferases [Enterococcus faecium]; NP_344795.1| acetyltransferase, GNAT family [Streptococcus pneumoniae TIGR4]). pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 3060149 5174508 CMM_2728 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223473.1 3059727 R 443906 CDS YP_001223474.1 148273913 5174468 3060249..3061322 1 NC_009480.1 conserved hypothetical protein (NP_825341.1| hypothetical protein SAV4164 [Streptomyces avermitilis MA-4680]; ZP_00119088.1| COG2931: RTX toxins and related Ca2+-binding proteins [Cytophaga hutchinsonii]).; hypothetical protein 3061322 5174468 CMM_2729 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223474.1 3060249 D 443906 CDS YP_001223475.1 148273914 5173884 3061491..3062450 1 NC_009480.1 putative sugar ABC transporter, permease component (NP_827989.1| putative transport system inner membrane protein [Streptomyces avermitilis MA-4680]; ZP_00228707.1| COG1175: ABC-type sugar transport systems,permease components [Kineococcus radiotolerans SRS30216]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 3062450 5173884 CMM_2730 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223475.1 3061491 D 443906 CDS YP_001223476.1 148273915 5174229 3062450..3063445 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00206070.1| COG0395: ABC-type sugar transport system,permease component [Enterococcus faecium]; NP_242732.1| sugar transport system (permease) (binding protein dependent transporter) [Bacillus halodurans C-125]). pfam00528, BPD_transp_1, Binding-protein-dependent transport system inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 3063445 5174229 CMM_2731 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223476.1 3062450 D 443906 CDS YP_001223477.1 148273916 5173723 complement(3063473..3063796) 1 NC_009480.1 conserved membrane protein, putative exporter, DMT family (AAR04620.1| SugE [Rhodococcus equi]; ZP_00291640.1| COG2076: Membrane transporters of cations and cationic drugs [Thermobifida fusca]). pfam00893,Multi_Drug_Res, Small Multidrug Resistance protein. This family is the Small Multidrug Resistance (SMR) family. InterPro: Integral membrane protein DUF7.; Function unclear; exporter DMT family membrane protein 3063796 5173723 CMM_2732 Clavibacter michiganensis subsp. michiganensis NCPPB 382 exporter DMT family membrane protein YP_001223477.1 3063473 R 443906 CDS YP_001223478.1 148273917 5174334 complement(3063923..3065281) 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (BAB18102.1| cyclomaltodextrin binding protein [Thermococcus sp. B1001]; ZP_00110980.2| COG1653: ABC-type sugar transport system, periplasmic component [Nostoc punctiforme PCC 73102]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein. InterPro: Bacterial extracellular solute-binding protein family 1.; Specificity unclear; putative sugar ABC transporter, substrate binding protein 3065281 5174334 CMM_2733 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001223478.1 3063923 R 443906 CDS YP_001223479.1 148273918 5174625 complement(3065381..3066292) 1 NC_009480.1 conserved hypothetical protein, putative esterase (NP_102879.1| esterase [Mesorhizobium loti MAFF303099]; NP_765650.1| hypothetical protein SE2095 [Staphylococcus epidermidis ATCC 12228]).; Function unclear; putative esterase 3066292 5174625 CMM_2734 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase YP_001223479.1 3065381 R 443906 CDS YP_001223480.1 148273919 5174507 complement(3066305..3067291) 1 NC_009480.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3067291 glpX 5174507 glpX Clavibacter michiganensis subsp. michiganensis NCPPB 382 fructose 1,6-bisphosphatase II YP_001223480.1 3066305 R 443906 CDS YP_001223481.1 148273920 5174610 complement(3067350..3068483) 1 NC_009480.1 conserved membrane protein, AI-E2 family (YP_062564.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121709.1| hypothetical protein nfa54930 [Nocardia farcinica IFM 10152]). ,pfam01594, UPF0118, Domain of unknown function DUF20. This transmembrane region is found in putative permeases and predicted transmembrane proteins it has no known function. InterPro: Domain of unknown function DUF20.; Conserved hypothetical protein; AI-E2 family membrane protein 3068483 5174610 CMM_2736 Clavibacter michiganensis subsp. michiganensis NCPPB 382 AI-E2 family membrane protein YP_001223481.1 3067350 R 443906 CDS YP_001223482.1 148273921 5175828 complement(3068672..3069394) 1 NC_009480.1 putative peptide ABC transporter, ATP-binding protein (NP_625651.1| putative ABC transport system ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_601218.1| ABC-type transporter, ATPase component [Corynebacterium glutamicum ATCC 13032]). pfam00005,ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative peptide ABC transporter, ATP-binding protein 3069394 5175828 CMM_2737 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, ATP-binding protein YP_001223482.1 3068672 R 443906 CDS YP_001223483.1 148273922 5175341 complement(3069391..3070488) 1 NC_009480.1 putative peptide ABC transporter, permease component (NP_625652.1| putative ABC transport system transmembrane protein [Streptomyces coelicolor A3(2)]; NP_940625.1| Putative ABC transport system integral membrane protein [Corynebacterium diphtheriae NCTC 13129]). InterPro: DUF214.; Specificity unclear; putative peptide ABC transporter, permease component 3070488 5175341 CMM_2738 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide ABC transporter, permease component YP_001223483.1 3069391 R 443906 CDS YP_001223484.1 148273923 5175010 3070638..3071813 1 NC_009480.1 putative two component system, sensor kinase (YP_061777.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_625653.1| putative two component system histidine kinase [Streptomyces coelicolor A3(2)]). pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two component system, sensor kinase 3071813 5175010 CMM_2739 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two component system, sensor kinase YP_001223484.1 3070638 D 443906 CDS YP_001223485.1 148273924 5174368 3071814..3072434 1 NC_009480.1 putative two-component system, response regulator (CAF20959.1| putative two component response regulator [Corynebacterium glutamicum ATCC 13032]; YP_061776.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]). pfam00072, Response_reg,Response regulator receiver domain. pfam00196, GerE,Bacterial regulatory proteins, luxR family. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator 3072434 5174368 CMM_2740 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001223485.1 3071814 D 443906 CDS YP_001223486.1 148273925 5175723 complement(3072689..3073270) 1 NC_009480.1 hypothetical protein 3073270 5175723 CMM_2741 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223486.1 3072689 R 443906 CDS YP_001223487.1 148273926 5175846 3073439..3074080 1 NC_009480.1 putative hydrolase (ZP_00291963.1| COG1011: Predicted hydrolase (HAD superfamily) [Thermobifida fusca]; NP_231282.1| hypothetical protein VC1645 [Vibrio cholerae O1 biovar eltor str. N16961]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase.; Function unclear; putative hydrolase 3074080 5175846 CMM_2742 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001223487.1 3073439 D 443906 CDS YP_001223488.1 148273927 5173945 complement(3074136..3074864) 1 NC_009480.1 conserved hypothetical protein (NP_825805.1| hypothetical protein SAV4628 [Streptomyces avermitilis MA-4680]; YP_120347.1| hypothetical protein nfa41340 [Nocardia farcinica IFM 10152]). pfam01590, GAF, GAF domain. pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. InterPro: GAF domain.; Function unclear; hypothetical protein 3074864 5173945 CMM_2743 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223488.1 3074136 R 443906 CDS YP_001223489.1 148273928 5173682 complement(3074915..3075628) 1 NC_009480.1 conserved hypothetical protein (NP_825806.1| hypothetical protein SAV4629 [Streptomyces avermitilis MA-4680]; AAD43816.1| unknown [Rhodococcus rhodochrous]). pfam03861, ANTAR, ANTAR domain. ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins.; hypothetical protein 3075628 5173682 CMM_2744 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223489.1 3074915 R 443906 CDS YP_001223490.1 148273929 5173318 3076020..3076745 1 NC_009480.1 conserved hypothetical protein, putative F420-dependent NADP reductase (NP_785408.1| hypothetical protein lp_1859 [Lactobacillus plantarum WCFS1]; CAF20864.1| putative secreted protein [Corynebacterium glutamicum ATCC 13032]; ZP_00030268.1| COG2085: Predicted dinucleotide-binding enzymes [Burkholderia fungorum]). pfam03807, F420_oxidored, NADP oxidoreductase coenzyme F420-dependent.; Function unclear; putative F420-dependent NADP reductase 3076745 5173318 CMM_2745 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative F420-dependent NADP reductase YP_001223490.1 3076020 D 443906 CDS YP_001223491.1 148273930 5175893 3076755..3077555 1 NC_009480.1 conserved membrane protein, putative permease (ZP_00226048.1| COG0730: Predicted permeases [Kineococcus radiotolerans SRS30216]; NP_746063.1| conserved hypothetical protein [Pseudomonas putida KT2440]). pfam01925, DUF81, Domain of unknown function DUF81. This integral membrane protein family has no known function. InterPro: Domain of unknown function DUF81.; Family membership; membrane protein, putative permease 3077555 5175893 CMM_2746 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative permease YP_001223491.1 3076755 D 443906 CDS YP_001223492.1 148273931 5174744 3077633..3077902 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (NP_640544.1| transcriptional regulator [Xanthomonas axonopodis pv. citri str. 306]; ZP_00193904.3| COG1396: Predicted transcriptional regulators [Mesorhizobium sp. BNC1]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. InterPro: Helix-turn-helix motif.; Specificity unclear; Cro/CI family transcriptional regulator 3077902 5174744 CMM_2747 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001223492.1 3077633 D 443906 CDS YP_001223493.1 148273932 5173517 3077895..3079214 1 NC_009480.1 conserved hypothetical protein, putatively involved in polysaccharide synthesis (P55564|Y4ME_RHISN HYPOTHETICAL 45.7 KD PROTEIN Y4ME; NP_768625.1| HipA protein [Bradyrhizobium japonicum]; ZP_00016645.1| COG3550: Uncharacterized protein related to capsule biosynthesis enzymes [Rhodospirillum rubrum]).; Family membership; hypothetical protein 3079214 5173517 CMM_2748 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223493.1 3077895 D 443906 CDS YP_001223494.1 148273933 5173227 3079341..3079994 1 NC_009480.1 hypothetical protein 3079994 5173227 CMM_2749 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223494.1 3079341 D 443906 CDS YP_001223495.1 148273934 5174293 3080032..3080556 1 NC_009480.1 hypothetical protein (YP_118843.1| hypothetical protein nfa26320 [Nocardia farcinica IFM 10152]).; hypothetical protein 3080556 5174293 CMM_2750 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223495.1 3080032 D 443906 CDS YP_001223496.1 148273935 5175568 3080942..3082618 1 NC_009480.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3082618 kdpA 5175568 kdpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 potassium-transporting ATPase subunit A YP_001223496.1 3080942 D 443906 CDS YP_001223497.1 148273936 5174546 3082615..3084765 1 NC_009480.1 putative potassium-transporting ATPase B chain, P-type ATPase (Potassium- translocating ATPase B chain) (YP_054834.1| potassium-transporting ATPase B chain [Propionibacterium acnes KPA171202]; Q9X8Z9|ATKB_STRCO Potassium- transporting ATPase B chain (Potassium-translocating ATPase B chain)). pfam00122, E1-E2_ATPase,E1-E2 ATPase.; High confidence in function and specificity; putative potassium-transporting ATPase B chain,P-type ATPase 3084765 kdpB 5174546 kdpB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative potassium-transporting ATPase B chain,P-type ATPase YP_001223497.1 3082615 D 443906 CDS YP_001223498.1 148273937 5174680 3084808..3085416 1 NC_009480.1 putative potassium-transporting ATPase C chain, P-type ATPase (Potassium- translocating ATPase C chain) (YP_054835.1| potassium-transporting ATPase C chain [Propionibacterium acnes KPA171202]; P65212|ATKC_MYCBO Potassium- transporting ATPase C chain (Potassium-translocating ATPase C chain) ). pfam02669, KdpC, K+-transporting ATPase, c chain.; High confidence in function and specificity; putative potassium-transporting ATPase C chain,P-type ATPase 3085416 kdpC 5174680 kdpC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative potassium-transporting ATPase C chain,P-type ATPase YP_001223498.1 3084808 D 443906 CDS YP_001223499.1 148273938 5174876 3085448..3087994 1 NC_009480.1 putative two-component system, sensor kinase (YP_054836.1| two-component sensor, KdpD [Propionibacterium acnes KPA171202]; O34971|KDPD_RATRA Sensor protein kdpD; T34823 probable turgor pressure sensor kdpD - Streptomyces coelicolor). MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM KDPD/KDPE INVOLVED IN THE REGULATION OF THE KDP OPERON. KDPD MAY FUNCTION AS A MEMBRANE-ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES KDPE IN RESPONSE TO ENVIRONMENTAL SIGNALS (BY SIMILARITY). pfam02702, KdpD, Osmosensitive K+ channel His kinase sensor domain. pfam00582, Usp, Universal stress protein family. pfam02518, HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Osmosensitive K+ channel His kinase sensor domain.; High confidence in function and specificity; putative two-component system, sensor kinase 3087994 kdpD 5174876 kdpD Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001223499.1 3085448 D 443906 CDS YP_001223500.1 148273939 5174568 3087991..3088695 1 NC_009480.1 putative two-component system, response regulator (YP_054837.1| two-component response regulator, KdpE [Propionibacterium acnes KPA171202]; CAB06852.1| PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN KDPE [Mycobacterium tuberculosis H37Rv]; T34824 probable turgor pressure regulator kdpE - Streptomyces coelicolor). pfam00072,Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal. InterPro: Response regulator receiver domain.; High confidence in function and specificity; putative two-component system, response regulator 3088695 kdpE 5174568 kdpE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001223500.1 3087991 D 443906 CDS YP_001223501.1 148273940 5175598 3088749..3089528 1 NC_009480.1 putative esterase/lipase (YP_062928.1| hypothetical protein Lxx21280 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00239215.1| lipase/acylhydrolase, putative [Bacillus cereus G9241]). pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.; Function unclear; putative esterase/lipase 3089528 5175598 CMM_2756 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative esterase/lipase YP_001223501.1 3088749 D 443906 CDS YP_001223502.1 148273941 5175209 3089570..3089929 1 NC_009480.1 Hypothetical protein; hypothetical protein 3089929 5175209 CMM_2757 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223502.1 3089570 D 443906 CDS YP_001223503.1 148273942 5173011 complement(3089943..3090152) 1 NC_009480.1 hypothetical protein (AC1282 hypothetical protein lmo1659 [imported] - Listeria monocytogenes (strain EGD-e)).; hypothetical protein 3090152 5173011 CMM_2758 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223503.1 3089943 R 443906 CDS YP_001223504.1 148273943 5174880 3090292..3091683 1 NC_009480.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 3091683 5174880 CMM_2759 Clavibacter michiganensis subsp. michiganensis NCPPB 382 DNA repair protein RadA YP_001223504.1 3090292 D 443906 CDS YP_001223505.1 148273944 5173638 complement(3091723..3092037) 1 NC_009480.1 putative transcriptional regulator, ArsR family (NP_789021.1| putative regulator [Tropheryma whipplei TW08/27]; NP_301626.1| putative ArsR-family transcriptional regulator [Mycobacterium leprae TN]). pfam01022, HTH_5, Bacterial regulatory protein, arsR family. InterPro: Bacterial regulatory proteins ArsR family.; Specificity unclear; ArsR family transcriptional regulator 3092037 5173638 CMM_2760 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ArsR family transcriptional regulator YP_001223505.1 3091723 R 443906 CDS YP_001223506.1 148273945 5173294 complement(3092149..3092307) 1 NC_009480.1 hypothetical protein 3092307 5173294 CMM_2761 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223506.1 3092149 R 443906 CDS YP_001223507.1 148273946 5174100 complement(3092425..3093090) 1 NC_009480.1 conserved hypothetical protein (YP_062932.1| hypothetical protein Lxx21320 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789027.1| putative secreted protein [Tropheryma whipplei TW08/27]).; hypothetical protein 3093090 5174100 CMM_2762 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223507.1 3092425 R 443906 CDS YP_001223508.1 148273947 5173711 complement(3093169..3093711) 1 NC_009480.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; N-acetylglutamate synthase 3093711 5173711 CMM_2763 Clavibacter michiganensis subsp. michiganensis NCPPB 382 N-acetylglutamate synthase YP_001223508.1 3093169 R 443906 CDS YP_001223509.1 148273948 5173725 complement(3093763..3094035) 1 NC_009480.1 Hypothetical protein; hypothetical protein 3094035 5173725 CMM_2764 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223509.1 3093763 R 443906 CDS YP_001223510.1 148273949 5173567 complement(3094037..3095713) 1 NC_009480.1 putative two-component system, sensor kinase (YP_061437.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_338421.1| sensor histidine kinase [Mycobacterium tuberculosis CDC1551]). pfam00512, HisKA, His Kinase A (phosphoacceptor) domain. Dimerisation and phosphoacceptor domain of histidine kinases. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor kinase 3095713 5173567 CMM_2765 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001223510.1 3094037 R 443906 CDS YP_001223511.1 148273950 5174787 complement(3095710..3096483) 1 NC_009480.1 putative two-component system, response regulator (YP_061436.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00225501.1| COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Kineococcus radiotolerans SRS30216]). pfam00072,Response_reg, Response regulator receiver domain. pfam00486, Trans_reg_C, Transcriptional regulatory protein, C terminal.; Specificity unclear; putative two-component system, response regulator 3096483 5174787 CMM_2766 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001223511.1 3095710 R 443906 CDS YP_001223512.1 148273951 5173859 complement(3096554..3097384) 1 NC_009480.1 Hypothetical protein; hypothetical protein 3097384 5173859 CMM_2767 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223512.1 3096554 R 443906 CDS YP_001223513.1 148273952 5173217 complement(3097455..3098483) 1 NC_009480.1 conserved membrane protein, putative exporter (YP_120073.1| putative transporter membrane protein [Nocardia farcinica IFM 10152]; NP_738469.1| putative integral membrane export protein [Corynebacterium efficiens YS-314]). pfam03741, TerC, Integral membrane protein TerC family.; Family membership; membrane protein, putative exporter 3098483 5173217 CMM_2768 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative exporter YP_001223513.1 3097455 R 443906 CDS YP_001223514.1 148273953 5173837 complement(3098668..3099606) 1 NC_009480.1 conserved hypothetical protein (ZP_00309143.1| COG0823: Periplasmic component of the Tol biopolymer transport system [Cytophaga hutchinsonii]; Q8UEU8|YG56_AGRT5 Hypothetical protein ATU1656/AGR_C_3050).; Family membership; hypothetical protein 3099606 5173837 CMM_2769 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223514.1 3098668 R 443906 CDS YP_001223515.1 148273954 5175588 complement(3099603..3100676) 1 NC_009480.1 conserved hypothetical protein (NP_630651.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)]; ZP_00186827.1| COG1082: Sugar phosphate isomerases/epimerases [Rubrobacter xylanophilus DSM 9941]). pfam01261, AP_endonuc_2, AP endonuclease family 2.; hypothetical protein 3100676 5175588 CMM_2770 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223515.1 3099603 R 443906 CDS YP_001223516.1 148273955 5174022 complement(3100799..3101581) 1 NC_009480.1 putative multidrug ABC transporter, permease component (NP_981776.1| ABC transporter, permease protein,putative [Bacillus cereus ATCC 10987]; AAF12290.1| conserved hypothetical protein [Deinococcus radiodurans]). pfam03699, UPF0182, Uncharacterised protein family (UPF0182). This family contains uncharacterised integral membrane proteins.; Specificity unclear; putative multidrug ABC transporter, permease component 3101581 5174022 CMM_2771 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative multidrug ABC transporter, permease component YP_001223516.1 3100799 R 443906 CDS YP_001223517.1 148273956 5174434 complement(3101578..3102534) 1 NC_009480.1 putative ABC transporter, ATP-binding protein (NP_629278.1| putative ABC transporter ATP-binding protein [Streptomyces coelicolor A3(2)]; NP_285331.1| ABC transporter, ATP-binding protein, putative [Deinococcus radiodurans R1]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter, ATP-binding protein 3102534 5174434 CMM_2772 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001223517.1 3101578 R 443906 CDS YP_001223518.1 148273957 5174062 complement(3102527..3103495) 1 NC_009480.1 conserved hypothetical protein, putative nitroreductase (NP_578479.1| putative NADH oxidase [Pyrococcus furiosus DSM 3638]; ZP_00294650.1| COG0778: Nitroreductase [Methanosarcina barkeri str. fusaro]).; Family membership; putative nitroreductase 3103495 5174062 CMM_2773 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nitroreductase YP_001223518.1 3102527 R 443906 CDS YP_001223519.1 148273958 5172982 complement(3103554..3104816) 1 NC_009480.1 conserved hypothetical protein (YP_055575.1| conserved protein DUF181 [Propionibacterium acnes KPA171202]; Q58494|YA94_METJA Hypothetical UPF0142 protein MJ1094). pfam02624, DUF181, Uncharacterized ACR,COG1944.; hypothetical protein 3104816 5172982 CMM_2774 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223519.1 3103554 R 443906 CDS YP_001223520.1 148273959 5174765 complement(3104813..3105724) 1 NC_009480.1 hypothetical protein 3105724 5174765 CMM_2775 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223520.1 3104813 R 443906 CDS YP_001223521.1 148273960 5173902 complement(3105735..3105947) 1 NC_009480.1 hypothetical protein 3105947 5173902 CMM_2776 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223521.1 3105735 R 443906 CDS YP_001223522.1 148273961 5175873 3106119..3106781 1 NC_009480.1 conserved hypothetical protein (YP_061428.1| hypothetical protein Lxx02960 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_950795.1| hypothetical protein [Onion yellows phytoplasma OY-M]; ZP_00040545.1| COG5377: Phage-related protein, predicted endonuclease [Xylella fastidiosa Ann-1]).; hypothetical protein 3106781 5175873 CMM_2777 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223522.1 3106119 D 443906 CDS YP_001223523.1 148273962 5175812 3106979..3108031 1 NC_009480.1 putative zinc-dependant oxidoreductase (YP_061427.1| zinc-binding oxidoreductase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_629556.1| putative zinc-binding oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00297421.1| COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases [Methanosarcina barkeri str. fusaro]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase. InterPro: Zinc-containing alcohol dehydrogenase superfamily.; Function unclear; putative zinc-dependant oxidoreductase 3108031 5175812 CMM_2778 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative zinc-dependant oxidoreductase YP_001223523.1 3106979 D 443906 CDS YP_001223524.1 148273963 5174226 complement(3108196..3109407) 1 NC_009480.1 putative carboxylesterase, putative penicillin-binding protein (ZP_00126504.2| COG1680: Beta-lactamase class C and other penicillin binding proteins [Pseudomonas syringae pv. syringae B728a]; NP_824788.1| putative esterase [Streptomyces avermitilis MA-4680]). pfam00144,Beta-lactamase, Beta-lactamase.; Function unclear; putative carboxylesterase 3109407 5174226 CMM_2779 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative carboxylesterase YP_001223524.1 3108196 R 443906 CDS YP_001223525.1 148273964 5173775 complement(3109404..3110396) 1 NC_009480.1 putative sugar hydrolase (CAD47861.1| putative sucrose hydrolase [Arthrobacter nicotinovorans]).; Function unclear; hypothetical protein 3110396 5173775 CMM_2780 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223525.1 3109404 R 443906 CDS YP_001223526.1 148273965 5174310 complement(3110396..3111220) 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00206541.1| COG0395: ABC-type sugar transport system,permease component [Bifidobacterium longum DJO10A]; NP_107402.1| ABC transporter, permease protein [Mesorhizobium loti MAFF303099]). pfam00528, BPD_transp_1,Binding-protein-dependent transport system inner membrane component. InterPro: Binding-protein-dependent transport systems inner membrane component.; Specificity unclear; putative sugar ABC transporter, permease component 3111220 5174310 CMM_2781 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223526.1 3110396 R 443906 CDS YP_001223527.1 148273966 5175853 complement(3111217..3112212) 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00206542.1| COG1175: ABC-type sugar transport systems,permease components [Bifidobacterium longum DJO10A]; ZP_00183308.1| COG1175: ABC-type sugar transport systems,permease components [Exiguobacterium sp. 255-15]).; Specificity unclear; putative sugar ABC transporter, permease component 3112212 5175853 CMM_2782 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223527.1 3111217 R 443906 CDS YP_001223528.1 148273967 5174527 complement(3112209..3113558) 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (ZP_00121121.2| COG1653: ABC-type sugar transport system, periplasmic component [Bifidobacterium longum DJO10A]; NP_107400.1| ABC transporter, periplasmic binding-protein [Mesorhizobium loti MAFF303099]). pfam01547, SBP_bac_1, Bacterial extracellular solute-binding protein.; Specificity unclear; putative sugar ABC transporter, substrate binding protein 3113558 5174527 CMM_2783 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001223528.1 3112209 R 443906 CDS YP_001223529.1 148273968 5174600 3113760..3114845 1 NC_009480.1 putative transcriptional regulator, LacI-family (ZP_00033618.1| COG1609: Transcriptional regulators [Burkholderia fungorum]; NP_231357.1| transcriptional regulator, LacI family [Vibrio cholerae O1 biovar eltor str. N16961]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; LacI family transcriptional regulator 3114845 5174600 CMM_2784 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001223529.1 3113760 D 443906 CDS YP_001223530.1 148273969 5175366 complement(3114871..3115467) 1 NC_009480.1 putative acetyltransferase (YP_119942.1| putative acetyltransferase [Nocardia farcinica IFM 10152]; NP_961723.1| hypothetical protein MAP2789 [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 3115467 5175366 CMM_2785 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223530.1 3114871 R 443906 CDS YP_001223531.1 148273970 5174123 complement(3115572..3116258) 1 NC_009480.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 3116258 rplA 5174123 rplA Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L1 YP_001223531.1 3115572 R 443906 CDS YP_001223532.1 148273971 5175822 complement(3116358..3116789) 1 NC_009480.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 3116789 rplK 5175822 rplK Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L11 YP_001223532.1 3116358 R 443906 CDS YP_001223533.1 148273972 5173612 complement(3116843..3117865) 1 NC_009480.1 putative transcription antitermination protein (YP_061423.1| transcription antitermination factor [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787843.1| transcription antitermination protein [Tropheryma whipplei str. Twist]). pfam02357, NusG, Transcription termination factor nusG. pfam00467, KOW, KOW motif. The KOW (Kyprides,Ouzounis, Woese) motif is found in a variety of ribosomal proteins and NusG. InterPro: Bacterial transcription antitermination protein nusG.; High confidence in function and specificity; putative transcription antitermination protein 3117865 nusG 5173612 nusG Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcription antitermination protein YP_001223533.1 3116843 R 443906 CDS YP_001223534.1 148273973 5175607 complement(3118053..3118325) 1 NC_009480.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 3118325 secE 5175607 secE Clavibacter michiganensis subsp. michiganensis NCPPB 382 preprotein translocase subunit SecE YP_001223534.1 3118053 R 443906 CDS YP_001223535.1 148273974 5175466 3118661..3119890 1 NC_009480.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 3119890 aspC 5175466 aspC Clavibacter michiganensis subsp. michiganensis NCPPB 382 aspartate aminotransferase YP_001223535.1 3118661 D 443906 CDS YP_001223536.1 148273975 5175126 complement(3119924..3121078) 1 NC_009480.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3121078 murB 5175126 murB Clavibacter michiganensis subsp. michiganensis NCPPB 382 UDP-N-acetylenolpyruvoylglucosamine reductase YP_001223536.1 3119924 R 443906 CDS YP_001223537.1 148273976 5174355 complement(3121086..3121520) 1 NC_009480.1 conserved hypothetical protein, putative dehydratase (YP_061419.1| hypothetical protein Lxx02820 [Leifsonia xyli subsp. xyli str.CTCB07]; NP_826079.1| hypothetical protein SAV4902 [Streptomyces avermitilis MA-4680]). , pfam01575, MaoC_dehydratas, MaoC like domain. ,InterPro: MaoC-like dehydratase domain.; Family membership; putative dehydratase 3121520 5174355 CMM_2792 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dehydratase YP_001223537.1 3121086 R 443906 CDS YP_001223538.1 148273977 5173581 complement(3121517..3121966) 1 NC_009480.1 conserved hypothetical protein, putative dehydratase (YP_061418.1| hypothetical protein Lxx02810 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292077.1| COG2030: Acyl dehydratase [Thermobifida fusca]). pfam05921, DUF875, Actinomycete protein of unknown function (DUF875). arcC: carbamate kinase; Family membership; hypothetical protein 3121966 5173581 CMM_2793 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223538.1 3121517 R 443906 CDS YP_001223540.1 148273979 5172983 complement(3122592..3122789) 1 NC_009480.1 hypothetical protein 3122789 5172983 CMM_2795 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223540.1 3122592 R 443906 CDS YP_001223541.1 148273980 5175187 complement(3123286..3124224) 1 NC_009480.1 putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme PCC 73102]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family.; Function unclear; putative oxidoreductase 3124224 5175187 CMM_2796 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223541.1 3123286 R 443906 CDS YP_001223542.1 148273981 5173223 3124385..3126124 1 NC_009480.1 putative alpha-glucosidase, glycosyl hydrolase family 13 (NP_626479.1| alpha-glucosidase [Streptomyces coelicolor A3(2)]; ZP_00089179.1| COG0366: Glycosidases [Azotobacter vinelandii]). pfam00128, Alpha-amylase, Alpha amylase, catalytic domain. Alpha amylase is classified as family 13 of the glycosyl hydrolases. InterPro: Glycoside hydrolase family 13.; Specificity unclear; alpha-glucosidase 3126124 aglC 5173223 aglC Clavibacter michiganensis subsp. michiganensis NCPPB 382 alpha-glucosidase YP_001223542.1 3124385 D 443906 CDS YP_001223543.1 148273982 5172967 complement(3126205..3127389) 1 NC_009480.1 putative membrane bound metalloendopeptidase,family M23 (NP_354816.1| AGR_C_3364p [Agrobacterium tumefaciens]; ZP_00193020.1| COG0739: Membrane proteins related to metalloendopeptidases [Mesorhizobium sp. BNC1]). pfam01551, Peptidase_M37, Peptidase family M23/M37. Members of this family are zinc metallopeptidases with a range of specificities. InterPro: Peptidase family M23/M37.; Family membership; M23 family membrane bound metalloendopeptidase 3127389 5172967 CMM_2798 Clavibacter michiganensis subsp. michiganensis NCPPB 382 M23 family membrane bound metalloendopeptidase YP_001223543.1 3126205 R 443906 CDS YP_001223544.1 148273983 5174608 complement(3127615..3128424) 1 NC_009480.1 putative inositol-1-monophosphatase (Q92M71|SUHB_RHIME Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase); AAF63339.1| myo-inositol-1-monophosphotase [Streptomyces spectabilis]). pfam00459,Inositol_P, Inositol monophosphatase family.; Specificity unclear; putative inositol-1-monophosphatase 3128424 suhB 5174608 suhB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative inositol-1-monophosphatase YP_001223544.1 3127615 R 443906 CDS YP_001223545.1 148273984 5175738 complement(3128470..3129210) 1 NC_009480.1 conserved membrane protein (NP_962548.1| hypothetical protein MAP3614 [Mycobacterium avium subsp. paratuberculosis str. k10]; NP_827020.1| hypothetical protein SAV5843 [Streptomyces avermitilis MA-4680]). pfam06912, DUF1275, Protein of unknown function (DUF1275).; Conserved hypothetical protein; hypothetical protein 3129210 5175738 CMM_2800 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223545.1 3128470 R 443906 CDS YP_001223546.1 148273985 5173212 complement(3129273..3130259) 1 NC_009480.1 putative oxidoreductase (NP_733626.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00106480.1| COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Nostoc punctiforme PCC 73102]). pfam00248, Aldo_ket_red, Aldo/keto reductase family.; Function unclear; putative oxidoreductase 3130259 5173212 CMM_2801 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223546.1 3129273 R 443906 CDS YP_001223547.1 148273986 5174401 3130585..3131073 1 NC_009480.1 conserved hypothetical protein (NP_826073.1| hypothetical protein SAV4896 [Streptomyces avermitilis MA-4680]; YP_061355.1| hypothetical protein Lxx01880 [Leifsonia xyli subsp. xyli str. CTCB07]). pfam04461,DUF520, Protein of unknown function (DUF520). Family of uncharacterised proteins.; hypothetical protein 3131073 5174401 CMM_2802 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223547.1 3130585 D 443906 CDS YP_001223548.1 148273987 5174175 3131155..3132624 1 NC_009480.1 putative phospholipase, cardiolipin synthetase (YP_062936.1| cardiolipin synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787192.1| cardiolipin synthetase [Tropheryma whipplei str. Twist]). pfam00614, PLDc,Phospholipase D. Active site motif (twice). InterPro: Phospholipase D/Transphosphatidylase.; High confidence in function and specificity; putative phospholipase, cardiolipin synthetase 3132624 5174175 CMM_2803 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phospholipase, cardiolipin synthetase YP_001223548.1 3131155 D 443906 CDS YP_001223549.1 148273988 5175768 complement(3132652..3133146) 1 NC_009480.1 putative transcriptional regulator, MarR family (ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]; ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. InterPro: Bacterial regulatory protein MarR family.; Specificity unclear; MarR family transcriptional regulator 3133146 5175768 CMM_2804 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223549.1 3132652 R 443906 CDS YP_001223550.1 148273989 5174252 complement(3133271..3133954) 1 NC_009480.1 putative signalpeptidase (NP_628711.1| putative type IV peptidase [Streptomyces coelicolor A3(2)]; ZP_00171774.1| COG1989: Type II secretory pathway,prepilin signal peptidase PulO and related peptidases [Methylobacillus flagellatus KT]; AAG18589.1| pilin biogenesis protein PilD [Pseudomonas fluorescens]).; Conserved hypothetical protein; hypothetical protein 3133954 5174252 CMM_2805 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223550.1 3133271 R 443906 CDS YP_001223551.1 148273990 5174969 complement(3134092..3135462) 1 NC_009480.1 putative ferredoxin/ferredoxin-NADP reductase (YP_061354.1| ferredoxin/ferredoxin-NADP reductase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121578.1| putative ferredoxin reductase [Nocardia farcinica IFM 10152]). possibly involved in menaquinone biosynthesis. pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.; Specificity unclear; putative ferredoxin/ferredoxin-NADP reductase 3135462 5174969 CMM_2806 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ferredoxin/ferredoxin-NADP reductase YP_001223551.1 3134092 R 443906 CDS YP_001223552.1 148273991 5174791 complement(3135553..3136626) 1 NC_009480.1 putative polyprenyl diphosphate synthase, involved in menaquinone biosynthesis (YP_061353.1| trans-hexaprenyltranstransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_826041.1| putative polyprenyl diphosphate synthase [Streptomyces avermitilis MA-4680]). pfam00348, polyprenyl_synt, Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; Specificity unclear; putative polyprenyl diphosphate synthase 3136626 menX 5174791 menX Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyprenyl diphosphate synthase YP_001223552.1 3135553 R 443906 CDS YP_001223553.1 148273992 5174079 complement(3136662..3137396) 1 NC_009480.1 putative menaquinone biosynthesis methyltransferase (YP_061352.1| ubiquinone/menaquinone biosynthesis methyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121345.1| putative ubiquinone/ menaquinone methyltransferase [Nocardia farcinica IFM 10152]). pfam01209, Ubie_methyltran, ubiE/COQ5 methyltransferase family. InterPro: ubiE/COQ5 methyltransferase.; Specificity unclear; putative menaquinone biosynthesis methyltransferase 3137396 menH 5174079 menH Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative menaquinone biosynthesis methyltransferase YP_001223553.1 3136662 R 443906 CDS YP_001223554.1 148273994 5174865 complement(3137404..3140142) 1 NC_009480.1 putative sugar MFS permease (NP_629540.1| probable integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00209176.1| COG0477: Permeases of the major facilitator superfamily [Magnetospirillum magnetotacticum MS-1]). pfam05977, DUF894, Bacterial protein of unknown function (DUF894).; Function unclear; putative sugar MFS permease 3140142 5174865 CMM_2809 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar MFS permease YP_001223554.1 3137404 R 443906 CDS YP_001223555.1 148273993 5175068 3137557..3138831 1 NC_009480.1 putative isochorismate synthase (YP_061351.1| isochorismate mutase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00292873.1| COG1169: Isochorismate synthase [Thermobifida fusca]). pfam00425, Chorismate_bind,chorismate binding enzyme. InterPro: Isochorismate synthase.; High confidence in function and specificity; putative isochorismate synthase 3138831 menF 5175068 menF Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative isochorismate synthase YP_001223555.1 3137557 D 443906 CDS YP_001223556.1 148273995 5175595 complement(3140139..3140684) 1 NC_009480.1 putative transcriptional regulator, ArsR family (NP_826320.1| hypothetical protein SAV5143 [Streptomyces avermitilis MA-4680]; NP_579519.1| transcriptional regulatory protein arsR family [Pyrococcus furiosus DSM 3638])., , pfam01022, HTH_5, Bacterial regulatory protein,arsR family.; Function unclear; hypothetical protein 3140684 5175595 CMM_2811 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223556.1 3140139 R 443906 CDS YP_001223557.1 148273996 5173302 complement(3140800..3142566) 1 NC_009480.1 menaquinone biosynthesis bifunctional protein menD contains two activities: 2-succinyl-6-hydroxy-24-cyclohexadiene- 1-carboxylate synthase (EC 4.1.3.-) and 2-oxoglutarate decarboxylase (EC 4.1.1.71) (Alpha-ketoglutarate decarboxylase)] (YP_061328.1| 2-oxoglutarate decarboxylase; 2-succinyl-6-hydroxy- 2,4-cyclohexadiene-1-carboxylate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789026.1| putative menaquinone biosynthesis protein MenD [Tropheryma whipplei TW08/27]. pfam02776,TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain. InterPro: Menaquinone biosynthesis protein.; High confidence in function and specificity; menaquinone biosynthesis bifunctional protein menD 3142566 menD 5173302 menD Clavibacter michiganensis subsp. michiganensis NCPPB 382 menaquinone biosynthesis bifunctional protein menD YP_001223557.1 3140800 R 443906 CDS YP_001223558.1 148273997 5173661 complement(3142573..3142995) 1 NC_009480.1 hypothetical membrane protein (YP_061327.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628654.1| putative membrane protein [Streptomyces coelicolor A3(2)]).; Hypothetical protein; hypothetical protein 3142995 5173661 CMM_2813 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223558.1 3142573 R 443906 CDS YP_001223559.1 148273998 5172933 3143135..3143515 1 NC_009480.1 hypothetical membrane protein (ZP_00292109.1| hypothetical protein Tfus02002535 [Thermobifida fusca]).; hypothetical protein 3143515 5172933 CMM_2814 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223559.1 3143135 D 443906 CDS YP_001223560.1 148273999 5175181 complement(3143526..3143903) 1 NC_009480.1 hypothetical protein 3143903 5175181 CMM_2815 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223560.1 3143526 R 443906 CDS YP_001223561.1 148274000 5175393 complement(3143909..3144793) 1 NC_009480.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3144793 menA 5175393 menA Clavibacter michiganensis subsp. michiganensis NCPPB 382 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001223561.1 3143909 R 443906 CDS YP_001223562.1 148274001 5175350 complement(3144952..3145704) 1 NC_009480.1 putative mutase (NP_822948.1| putative mutase [Streptomyces avermitilis MA-4680]; NP_896839.1| putative phosphoglycerate mutase family protein [Synechococcus sp. WH 8102]; NP_962249.1| EntD [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00300, PGAM,Phosphoglycerate mutase family.; Family membership; putative mutase 3145704 5175350 CMM_2817 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative mutase YP_001223562.1 3144952 R 443906 CDS YP_001223563.1 148274002 5172936 complement(3145803..3146711) 1 NC_009480.1 conserved hypothetical protein (YP_061292.1| beta-lactamase related protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00106502.1| COG2367: Beta-lactamase class A [Nostoc punctiforme PCC 73102]).; hypothetical protein 3146711 5172936 CMM_2818 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223563.1 3145803 R 443906 CDS YP_001223564.1 148274003 5173281 complement(3146734..3148716) 1 NC_009480.1 putative metallopeptidase, family M13 (YP_061291.1| metallopeptidase [Leifsonia xyli subsp. xyli str. CTCB07]; YP_121856.1| putative peptidase [Nocardia farcinica IFM 10152]). pfam05649, Peptidase_M13_N,Peptidase family M13. pfam01431, Peptidase_M13, Peptidase family M13.; Function unclear; metallopeptidase family M13 3148716 5173281 CMM_2819 Clavibacter michiganensis subsp. michiganensis NCPPB 382 metallopeptidase family M13 YP_001223564.1 3146734 R 443906 CDS YP_001223565.1 148274004 5174023 3148824..3149030 1 NC_009480.1 putative transcriptional regulator, Cro/CI family (NP_639310.1| transcriptional regulator [Xanthomonas campestris pv. campestris str. ATCC 33913]; ZP_00225863.1| COG1476: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI.; Specificity unclear; Cro/CI family transcriptional regulator 3149030 5174023 CMM_2820 Clavibacter michiganensis subsp. michiganensis NCPPB 382 Cro/CI family transcriptional regulator YP_001223565.1 3148824 D 443906 CDS YP_001223566.1 148274005 5175573 3149014..3149415 1 NC_009480.1 Hypothetical protein; hypothetical protein 3149415 5175573 CMM_2821 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223566.1 3149014 D 443906 CDS YP_001223567.1 148274006 5174511 3149521..3150804 1 NC_009480.1 putative xanthine/uracil family permease, NCS2 family (YP_104807.1| xanthine/uracil permease family protein [Burkholderia mallei ATCC 23344]; ZP_00275416.1| COG2233: Xanthine/uracil permeases [Ralstonia metallidurans CH34]). pfam00860, Xan_ur_permease, Permease family.; Specificity unclear; xanthine/uracil family permease 3150804 5174511 CMM_2822 Clavibacter michiganensis subsp. michiganensis NCPPB 382 xanthine/uracil family permease YP_001223567.1 3149521 D 443906 CDS YP_001223568.1 148274007 5175161 3150990..3152369 1 NC_009480.1 conserved membrane protein (YP_062737.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055965.1| hypothetical protein PPA1260 [Propionibacterium acnes KPA171202]).; Conserved hypothetical protein; hypothetical protein 3152369 5175161 CMM_2823 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223568.1 3150990 D 443906 CDS YP_001223569.1 148274008 5175502 complement(3152348..3154141) 1 NC_009480.1 catalyzes the hydrolysis of allophanate; allophanate hydrolase 3154141 5175502 CMM_2824 Clavibacter michiganensis subsp. michiganensis NCPPB 382 allophanate hydrolase YP_001223569.1 3152348 R 443906 CDS YP_001223570.1 148274009 5173116 complement(3154138..3154869) 1 NC_009480.1 conserved hypothetical protein, isochorismatase family (NP_772791.1| hypothetical isochorismatase family protein [Bradyrhizobium japonicum]; ZP_00125671.2| COG1335: Amidases related to nicotinamidase [Pseudomonas syringae pv. syringae B728a]). pfam00857, Isochorismatase,Isochorismatase family. This family are hydrolase enzymes.; hypothetical protein 3154869 5173116 CMM_2825 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223570.1 3154138 R 443906 CDS YP_001223571.1 148274010 5175574 complement(3154866..3156242) 1 NC_009480.1 putative cytosine permease, NCS1 family (NP_937310.1| purine-cytosine permease [Vibrio vulnificus YJ016]; NP_462243.1| putative purine-cytosine permease [Salmonella typhimurium LT2]). pfam02133, Transp_cyt_pur,Permease for cytosine/purines, uracil, thiamine,allantoin. InterPro: Permeases for cytosine/purines uracil thiamine allantoin; Specificity unclear; cytosine permease 3156242 5175574 CMM_2826 Clavibacter michiganensis subsp. michiganensis NCPPB 382 cytosine permease YP_001223571.1 3154866 R 443906 CDS YP_001223572.1 148274011 5175312 3156391..3157080 1 NC_009480.1 putative transcriptional regulator, GntR-family (NP_715986.1| transcriptional regulator. GntR family [Shewanella oneidensis MR-1]; NP_823595.1| putative GntR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam00392, GntR, Bacterial regulatory proteins,gntR family.; Specificity unclear; GntR family transcriptional regulator 3157080 5175312 CMM_2827 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001223572.1 3156391 D 443906 CDS YP_001223573.1 148274012 5173756 complement(3157101..3157799) 1 NC_009480.1 putative phosphatase (NP_662590.1| hydrolase,haloacid dehalogenase- like family [Chlorobium tepidum TLS]; ZP_00306861.1| COG0546: Predicted phosphatases [Ferroplasma acidarmanus]; ZP_00057308.1| COG0546: Predicted phosphatases [Thermobifida fusca]). pfam00702,Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases.; Function unclear; putative phosphatase 3157799 5173756 CMM_2828 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001223573.1 3157101 R 443906 CDS YP_001223574.1 148274013 5175928 complement(3157838..3158350) 1 NC_009480.1 putative transcriptional regulator, MarR family (YP_062606.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824748.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]). pfam01047, MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; hypothetical protein 3158350 5175928 CMM_2829 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223574.1 3157838 R 443906 CDS YP_001223575.1 148274014 5174965 3158485..3159390 1 NC_009480.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 3159390 mmuM 5174965 mmuM Clavibacter michiganensis subsp. michiganensis NCPPB 382 homocysteine methyltransferase YP_001223575.1 3158485 D 443906 CDS YP_001223576.1 148274015 5175712 complement(3159476..3160339) 1 NC_009480.1 putative nucleoside-diphosphate-sugar epimerase (YP_062550.1| hypothetical protein Lxx16700 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_600590.1| predicted nucleoside-diphosphate-sugar epimerase [Corynebacterium glutamicum ATCC 13032]). only weak similarity to: pfam02716, Isoflavone_redu, Isoflavone reductase.; Function unclear; putative nucleoside-diphosphate-sugar epimerase 3160339 5175712 CMM_2831 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001223576.1 3159476 R 443906 CDS YP_001223577.1 148274016 5175864 3160454..3160834 1 NC_009480.1 putative transcriptional regulator (NP_629709.1| conserved hypothetical protein SC7A1.18c [Streptomyces coelicolor A3(2)]; NP_695657.1| narrowly conserved hypothetical protein with duf24 [Bifidobacterium longum NCC2705]). pfam01638, DUF24, Transcriptional regulator.; Function unclear; putative transcriptional regulator 3160834 5175864 CMM_2832 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative transcriptional regulator YP_001223577.1 3160454 D 443906 CDS YP_001223578.1 148274017 5174672 3160911..3162206 1 NC_009480.1 putative MFS permease (NP_631565.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]; ZP_00294170.1| COG0477: Permeases of the major facilitator superfamily [Thermobifida fusca]). pfam00083,Sugar_tr, Sugar (and other) transporter.; Function unclear; putative MFS permease 3162206 5174672 CMM_2833 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative MFS permease YP_001223578.1 3160911 D 443906 CDS YP_001223579.1 148274018 5175870 3162309..3163175 1 NC_009480.1 putative aldo/keto reductase (YP_119166.1| putative oxidoreductase [Nocardia farcinica IFM 10152]; NP_624627.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family.; Function unclear; putative oxidoreductase 3163175 5175870 CMM_2834 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223579.1 3162309 D 443906 CDS YP_001223580.1 148274019 5175734 complement(3163203..3164138) 1 NC_009480.1 putative transcriptional regulator, LysR-family (ZP_00226031.1| COG0583: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; ZP_00057998.1| COG0583: Transcriptional regulator [Thermobifida fusca]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate, LysR substrate binding domain.; Specificity unclear; LysR family transcriptional regulator 3164138 5175734 CMM_2835 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001223580.1 3163203 R 443906 CDS YP_001223581.1 148274020 5173087 3164228..3165205 1 NC_009480.1 putative permease, DMT family (NP_823168.1| hypothetical protein SAV1992 [Streptomyces avermitilis MA-4680]; ZP_00279369.1| COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily [Burkholderia fungorum LB400]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (twice).; Specificity unclear; permease DMT family 3165205 5173087 CMM_2836 Clavibacter michiganensis subsp. michiganensis NCPPB 382 permease DMT family YP_001223581.1 3164228 D 443906 CDS YP_001223582.1 148274021 5173763 3165202..3165591 1 NC_009480.1 putative membrane protein (ZP_00199035.1| hypothetical protein Krad07002569 [Kineococcus radiotolerans SRS30216]; NP_599355.1| predicted membrane protein [Corynebacterium glutamicum ATCC 13032]). pfam02656, DUF202, Domain of unknown function DUF. InterPro: DUF202.; hypothetical protein 3165591 5173763 CMM_2837 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223582.1 3165202 D 443906 CDS YP_001223583.1 148274022 5173182 3165588..3165944 1 NC_009480.1 putative membrane protein (ZP_00292261.1| hypothetical protein Tfus02002381 [Thermobifida fusca]; NP_418131.1| hypothetical protein b3675 [Escherichia coli K12]).; hypothetical protein 3165944 5173182 CMM_2838 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223583.1 3165588 D 443906 CDS YP_001223584.1 148274023 5175832 complement(3165974..3166843) 1 NC_009480.1 conserved hypothetical protein, putative nucleoside-diphosphate-sugar epimerase (NP_792815.1| conserved hypothetical protein [Pseudomonas syringae pv. tomato str. DC3000]; NP_969467.1| conserved hypothetical protein [Bdellovibrio bacteriovorus HD100]).; Family membership; putative nucleoside-diphosphate-sugar epimerase 3166843 5175832 CMM_2839 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative nucleoside-diphosphate-sugar epimerase YP_001223584.1 3165974 R 443906 CDS YP_001223585.1 148274024 5175381 complement(3167078..3167968) 1 NC_009480.1 putative sugar kinase (ZP_00293678.1| COG0524: Sugar kinases, ribokinase family [Thermobifida fusca]; ZP_00337675.1| COG0524: Sugar kinases, ribokinase family [Silicibacter sp. TM1040]). pfam00294, PfkB, pfkB family carbohydrate kinase. This family includes a variety of carbohydrate and pyrimidine kinases.; Specificity unclear; putative sugar kinase 3167968 5175381 CMM_2840 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar kinase YP_001223585.1 3167078 R 443906 CDS YP_001223586.1 148274025 5174027 complement(3167961..3169025) 1 NC_009480.1 putative ranscriptional regulator, LacI-family (NP_625372.1| putative lacI-family transcriptional regulator [Streptomyces coelicolor A3(2)]; ZP_00186316.1| COG1609: Transcriptional regulators [Rubrobacter xylanophilus DSM 9941]). pfam00356, LacI, Bacterial regulatory proteins, lacI family. pfam00532, Peripla_BP_1,Periplasmic binding proteins and sugar binding domain of the LacI family. InterPro: Periplasmic binding proteins and sugar binding domain LacI family.; Specificity unclear; LacI family transcriptional regulator 3169025 5174027 CMM_2841 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LacI family transcriptional regulator YP_001223586.1 3167961 R 443906 CDS YP_001223587.1 148274026 5175700 3169139..3170239 1 NC_009480.1 putative sugar ABC transporter, substrate binding protein (NP_530772.1| ABC transporter, substrate binding protein [sugar] [Agrobacterium tumefaciens str. C58]; NP_107869.1| sugar ABC transporter, periplasmic sugar-binding protein [Mesorhizobium loti MAFF303099]). pfam00532, Peripla_BP_1, Periplasmic binding proteins and sugar binding domain of the LacI family.; Specificity unclear; putative sugar ABC transporter, substrate binding protein 3170239 5175700 CMM_2842 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, substrate binding protein YP_001223587.1 3169139 D 443906 CDS YP_001223588.1 148274027 5174887 3170242..3171288 1 NC_009480.1 putative sugar ABC transporter, permease component (ZP_00338367.1| COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Silicibacter sp. TM1040]; AAC16210.1| ribose transport system permease protein RbsC [Rhodobacter capsulatus]). pfam02653, BPD_transp_2,Branched-chain amino acid transport system / permease component.; Specificity unclear; putative sugar ABC transporter, permease component 3171288 5174887 CMM_2843 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, permease component YP_001223588.1 3170242 D 443906 CDS YP_001223589.1 148274028 5175353 3171285..3172082 1 NC_009480.1 putative sugar ABC transporter, ATP-binding protein (NP_530774.1| ABC transporter, nucleotide binding/ATPase protein [sugar] [Agrobacterium tumefaciens str. C58]; NP_107871.1| sugar ABC transporter, ATP binding protein [Mesorhizobium loti MAFF303099]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative sugar ABC transporter, ATP-binding protein 3172082 5175353 CMM_2844 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative sugar ABC transporter, ATP-binding protein YP_001223589.1 3171285 D 443906 CDS YP_001223590.1 148274029 5174968 3172079..3172372 1 NC_009480.1 conserved hypothetical protein (NP_826883.1| hypothetical protein SAV5706 [Streptomyces avermitilis MA-4680]; ZP_00274581.1| COG1359: Uncharacterized conserved protein [Ralstonia metallidurans CH34]). pfam03992, ABM,Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. InterPro: DUF176.; Function unclear; hypothetical protein 3172372 5174968 CMM_2845 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223590.1 3172079 D 443906 CDS YP_001223591.1 148274030 5175721 complement(3172596..3173699) 1 NC_009480.1 putative plasmid maintenance system, antidote protein (ZP_00271057.1| COG3093: Plasmid maintenance system antidote protein [Rhodospirillum rubrum]; YP_112809.1| DNA-binding protein [Methylococcus capsulatus str. Bath]). pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. pfam06114, DUF955, Domain of unknown function (DUF955). Family of bacterial and viral proteins with undetermined function.; Conserved hypothetical protein; putative plasmid maintenance system, antidote protein 3173699 5175721 CMM_2846 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative plasmid maintenance system, antidote protein YP_001223591.1 3172596 R 443906 CDS YP_001223592.1 148274031 5173615 complement(3173728..3174063) 1 NC_009480.1 putative plasmid maintemance system, killer protein 3174063 5173615 CMM_2847 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative plasmid maintemance system, killer protein YP_001223592.1 3173728 R 443906 CDS YP_001223593.1 148274032 5173692 complement(3174495..3175247) 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (ZP_00194667.1| COG1028: Dehydrogenases with different specificities (related to short- chain alcohol dehydrogenases) [Mesorhizobium sp. BNC1]; NP_631416.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Specificity unclear; putative short chain dehydrogenase/oxidoreductase 3175247 5173692 CMM_2848 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001223593.1 3174495 R 443906 CDS YP_001223594.1 148274033 5175707 3175441..3177510 1 NC_009480.1 conserved hypothetical protein, putative phosphatase (NP_825582.1| hypothetical protein SAV4405 [Streptomyces avermitilis MA-4680]; ZP_00188457.2| COG3211: Predicted phosphatase [Rubrobacter xylanophilus DSM 9941]). pfam05787, DUF839, Bacterial protein of unknown function (DUF839). This family consists of several bacterial proteins of unknown function.; Family membership; putative phosphatase 3177510 5175707 CMM_2849 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phosphatase YP_001223594.1 3175441 D 443906 CDS YP_001223595.1 148274034 5175044 3177707..3178060 1 NC_009480.1 hypothetical protein (NP_870934.1| hypothetical protein RB13228 [Rhodopirellula baltica SH 1]; AAO55387.1| conserved hypothetical protein [Pseudomonas syringae pv. tomato str. DC3000]).; hypothetical protein 3178060 5175044 CMM_2850 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223595.1 3177707 D 443906 CDS YP_001223596.1 148274035 5174145 3178108..3178713 1 NC_009480.1 putative membrane protein (NP_959547.1| hypothetical protein MAP0613c [Mycobacterium avium subsp. paratuberculosis str. k10]; ZP_00293703.1| hypothetical protein Tfus02001064 [Thermobifida fusca]).; hypothetical protein 3178713 5174145 CMM_2851 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223596.1 3178108 D 443906 CDS YP_001223597.1 148274036 5175115 3178770..3179507 1 NC_009480.1 putative zinc transporter, ZIP family (ZP_00110916.1| COG0428: Predicted divalent heavy-metal cations transporter [Nostoc punctiforme PCC 73102]; ZP_00293877.1| COG0428: Predicted divalent heavy-metal cations transporter [Thermobifida fusca]). pfam02535, Zip,ZIP Zinc transporter. The ZIP family consists of zinc transport proteins and many putative metal transporters.; Specificity unclear; ZIP family zinc transporter 3179507 5175115 CMM_2852 Clavibacter michiganensis subsp. michiganensis NCPPB 382 ZIP family zinc transporter YP_001223597.1 3178770 D 443906 CDS YP_001223598.1 148274037 5174307 complement(3179562..3180116) 1 NC_009480.1 putative transcriptional regulator, MarR family (NP_824140.1| putative MarR-family transcriptional regulator [Streptomyces avermitilis MA-4680]; NP_629113.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam01047,MarR, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system.; Specificity unclear; MarR family transcriptional regulator 3180116 5174307 CMM_2853 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223598.1 3179562 R 443906 CDS YP_001223599.1 148274038 5174197 3180258..3182069 1 NC_009480.1 putative ATPase involved in chromosome partitioning (NP_301161.1| conserved hypothetical protein [Mycobacterium leprae TN]; ZP_00056814.1| COG0455: ATPases involved in chromosome partitioning [Thermobifida fusca]; AAP73957.1| putative septum site-determining protein (MinD) [Rhodococcus erythropolis]).; Family membership; hypothetical protein 3182069 5174197 CMM_2854 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223599.1 3180258 D 443906 CDS YP_001223600.1 148274039 5174976 3182066..3183478 1 NC_009480.1 conserved membrane protein, putative multidrug exporter MOP(MATE) family (NP_628096.1| putative membrane protein [Streptomyces coelicolor A3(2)]; ZP_00291615.1| COG0534: Na+-driven multidrug efflux pump [Thermobifida fusca])., , pfam01554, MatE, MatE. The MatE domain (twice).; Specificity unclear; multidrug exporter MOPMATE family membrane protein 3183478 5174976 CMM_2855 Clavibacter michiganensis subsp. michiganensis NCPPB 382 multidrug exporter MOPMATE family membrane protein YP_001223600.1 3182066 D 443906 CDS YP_001223601.1 148274040 5174073 complement(3183494..3184354) 1 NC_009480.1 putative aldo/keto reductase (YP_074487.1| oxidoreductase [Symbiobacterium thermophilum IAM 14863]; ZP_00281237.1| COG0656: Aldo/keto reductases, related to diketogulonate reductase [Burkholderia fungorum LB400]). pfam00248, Aldo_ket_red, Aldo/keto reductase family. InterPro: Aldo/keto reductase family. holB: DNA polymerase III delta prime s; Function unclear; putative aldo/keto reductase 3184354 5174073 CMM_2856 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aldo/keto reductase YP_001223601.1 3183494 R 443906 CDS YP_001223602.1 148274041 5173811 complement(3184406..3184846) 1 NC_009480.1 hypothetical protein 3184846 5173811 CMM_2857 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223602.1 3184406 R 443906 CDS YP_001223603.1 148274042 5175868 complement(3184856..3185875) 1 NC_009480.1 conserved hypothetical protein, putative protein-S-isoprenylcysteine methyltransferase (Isoprenylcysteine carboxylmethyltransferase) (NP_869869.1| ; ZP_00191379.2| COG2020: Putative protein-S-isoprenylcysteine methyltransferase [Kineococcus radiotolerans SRS30216]).; Function unclear; S-isoprenylcysteine methyltransferase-like protein 3185875 5175868 CMM_2858 Clavibacter michiganensis subsp. michiganensis NCPPB 382 S-isoprenylcysteine methyltransferase-like protein YP_001223603.1 3184856 R 443906 CDS YP_001223604.1 148274043 5175134 complement(3185872..3186387) 1 NC_009480.1 conserved hypothetical protein (EAL05363.1| conserved hypothetical protein [Listeria monocytogenes str. 1/2a F6854]; NP_347636.1| Uncharacterized protein,homolog of yhfF B.subtilis [Clostridium acetobutylicum ATCC 824]). pfam06171, DUF984, Protein of unknown function (DUF984).; hypothetical protein 3186387 5175134 CMM_2859 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223604.1 3185872 R 443906 CDS YP_001223605.1 148274044 5175311 3186445..3186981 1 NC_009480.1 Hypothetical protein; hypothetical protein 3186981 5175311 CMM_2860 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223605.1 3186445 D 443906 CDS YP_001223606.1 148274045 5175356 3187048..3187608 1 NC_009480.1 putative acetyltransferase (NP_644579.1| acetyltransferase [Xanthomonas axonopodis pv. citri str. 306]; NP_925980.1| probable acetyltransferase [Gloeobacter violaceus PCC 7421]). pfam00583,Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Function unclear; putative acetyltransferase 3187608 5175356 CMM_2861 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223606.1 3187048 D 443906 CDS YP_001223607.1 148274046 5174802 complement(3187605..3188123) 1 NC_009480.1 putative acetyltransferase (NP_626478.1| putative acetyltransferase [Streptomyces coelicolor A3(2)]; NP_925980.1| probable acetyltransferase [Gloeobacter violaceus PCC 7421]). pfam00583, Acetyltransf_1,Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions. InterPro: GCN5-related N-acetyltransferase.; Family membership; putative acetyltransferase 3188123 5174802 CMM_2862 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative acetyltransferase YP_001223607.1 3187605 R 443906 CDS YP_001223608.1 148274047 5173520 3188177..3188785 1 NC_009480.1 conserved membrane protein (NP_294914.1| hypothetical protein [Deinococcus radiodurans R1]; ZP_00185697.1| COG3548: Predicted integral membrane protein [Rubrobacter xylanophilus DSM 9941]). pfam06736,DUF1211, Protein of unknown function (DUF1211).; Conserved hypothetical protein; hypothetical protein 3188785 5173520 CMM_2863 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223608.1 3188177 D 443906 CDS YP_001223609.1 148274048 5175398 3188818..3189879 1 NC_009480.1 conserved membrane protein, putative DMT transporter (YP_063076.1| integral membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_733531.1| putative integral membrane protein [Streptomyces coelicolor A3(2)]). pfam00892, DUF6, Integral membrane protein DUF6. This family includes many hypothetical membrane proteins of unknown function (twice). InterPro: Integral membrane protein DUF6.; Family membership; membrane protein, putative DMT transporter 3189879 5175398 CMM_2864 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative DMT transporter YP_001223609.1 3188818 D 443906 CDS YP_001223610.1 148274049 5173668 3189889..3190584 1 NC_009480.1 conserved hypothetical protein (YP_061283.1| hypothetical protein Lxx00930 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_117280.1| hypothetical protein nfa10710 [Nocardia farcinica IFM 10152]). pfam01939, DUF91, Protein of unknown function DUF91.; hypothetical protein 3190584 5173668 CMM_2865 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223610.1 3189889 D 443906 CDS YP_001223611.1 148274050 5173170 3190640..3191359 1 NC_009480.1 conserved hypothetical protein, putative hydrolase (YP_061281.1| hydrolase, haloacid dehalogenase-like family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_816534.1| hydrolase, haloacid dehalogenase-like family [Enterococcus faecalis V583]). pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. InterPro: Haloacid dehalogenase/epoxide hydrolase family. hstdl_phs_rel: histidinol phosphatase-r; putative hydrolase 3191359 5173170 CMM_2866 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase YP_001223611.1 3190640 D 443906 CDS YP_001223612.1 148274051 5172998 3191473..3191934 1 NC_009480.1 putative transcriptional regulator, MarR family (ZP_00227991.1| COG1846: Transcriptional regulators [Kineococcus radiotolerans SRS30216]; ZP_00058332.1| COG1846: Transcriptional regulators [Thermobifida fusca]). pfam01047, MarR, MarR family. InterPro: Bacterial regulatory protein MarR family.; Specificity unclear; MarR family transcriptional regulator 3191934 5172998 CMM_2867 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223612.1 3191473 D 443906 CDS YP_001223613.1 148274052 5173652 3191994..3192863 1 NC_009480.1 putative membrane-bound Zn-dependent protease (YP_118728.1| hypothetical protein nfa25170 [Nocardia farcinica IFM 10152]; NP_736926.1| hypothetical protein CE0316 [Corynebacterium efficiens YS-314]).; Function unclear; putative membrane-bound Zn-dependent protease 3192863 5173652 CMM_2868 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative membrane-bound Zn-dependent protease YP_001223613.1 3191994 D 443906 CDS YP_001223614.1 148274053 5175690 3193115..3194224 1 NC_009480.1 conserved membrane protein (YP_061832.1| hypothetical protein Lxx08200 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_738791.1| hypothetical protein CE2181 [Corynebacterium efficiens YS-314]). contains two domains: N-terminal: COG1633, Uncharacterized conserved protein [Function unknown]; cd01044, Ferritin_like_CCC1, Ferritin-like domain present at the N-terminus of the iron transport protein CCC1 of some eubacteria and archaebacteria, and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. This uncharacterized domain has the conserved residues of a diiron center. C-terminal: pfam01988, DUF125, Integral membrane protein DUF125. This family of predicted integral membrane proteins has no known function.; hypothetical protein 3194224 5175690 CMM_2869 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223614.1 3193115 D 443906 CDS YP_001223615.1 148274054 5173637 3194287..3194934 1 NC_009480.1 hypothetical protein 3194934 5173637 CMM_2870 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223615.1 3194287 D 443906 CDS YP_001223616.1 148274055 5175468 complement(3194955..3196445) 1 NC_009480.1 putative polygalacturonase (Pectinase) (YP_061794.1| endopolygalacturonase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_638805.1| endopolygalacturonase [Xanthomonas campestris pv. campestris str. ATCC 33913]). , pfam00295, Glyco_hydro_28, Glycosyl hydrolases family 28. , InterPro: Glycoside hydrolase family 28.; High confidence in function and specificity; hypothetical protein 3196445 pgaA 5175468 pgaA Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223616.1 3194955 R 443906 CDS YP_001223617.1 148274056 5174871 complement(3196563..3197429) 1 NC_009480.1 putative hydrolase/acyltransferase (NP_421198.1| acetoin dehydrogenase E2 component, putative [Caulobacter crescentus CB15]; BAC75995.1| meta cleavage compound hydrolase [Terrabacter sp. DBF63]). pfam00561,Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.; Family membership; putative hydrolase/acyltransferase 3197429 5174871 CMM_2872 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative hydrolase/acyltransferase YP_001223617.1 3196563 R 443906 CDS YP_001223618.1 148274057 5175753 3197579..3198913 1 NC_009480.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase 3198913 5175753 CMM_2873 Clavibacter michiganensis subsp. michiganensis NCPPB 382 diaminobutyrate--2-oxoglutarate aminotransferase YP_001223618.1 3197579 D 443906 CDS YP_001223619.1 148274058 5175463 complement(3198968..3199315) 1 NC_009480.1 conserved hypothetical protein (NP_142428.2| hypothetical protein PH0448 [Pyrococcus horikoshii OT3]; NP_614860.1| hypothetical protein MK1577 [Methanopyrus kandleri AV19]). pfam04266, DUF437, Protein of unknown function (DUF437).; hypothetical protein 3199315 5175463 CMM_2874 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223619.1 3198968 R 443906 CDS YP_001223620.1 148274059 5175383 complement(3199354..3199821) 1 NC_009480.1 conserved hypothetical protein (YP_061264.1| hypothetical protein Lxx00670 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_824697.1| hypothetical protein SAV3520 [Streptomyces avermitilis MA-4680]). weak similarity to: COG4319, Ketosteroid isomerase homolog [Function unknown].; hypothetical protein 3199821 5175383 CMM_2875 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223620.1 3199354 R 443906 CDS YP_001223621.1 148274060 5175109 complement(3199850..3200512) 1 NC_009480.1 putative two-component system, response regulator (NP_599321.1| two-component system response regulator [Corynebacterium glutamicum ATCC 13032]; YP_062659.1| two-component system, regulatory protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_823607.1| putative two-component system response regulator [Streptomyces avermitilis MA-4680]). pfam00072, Response_reg, Response regulator receiver domain. InterPro: Response regulator receiver domain.; Specificity unclear; putative two-component system, response regulator 3200512 5175109 CMM_2876 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, response regulator YP_001223621.1 3199850 R 443906 CDS YP_001223622.1 148274061 5174457 complement(3200509..3202332) 1 NC_009480.1 putative two-component system, sensor kinase (YP_062660.1| two-component system, sensor protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_599320.1| two-component system sensory transduction histidine kinase [Corynebacterium glutamicum ATCC 13032]; NP_629952.1| putative two-component sensor [Streptomyces coelicolor A3(2)]). pfam00989, PAS, PAS domain. pfam02518, HATPase_c,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. InterPro: Histidine kinase C-terminal.; Specificity unclear; putative two-component system, sensor kinase 3202332 5174457 CMM_2877 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative two-component system, sensor kinase YP_001223622.1 3200509 R 443906 CDS YP_001223623.1 148274062 5174799 3202468..3203919 1 NC_009480.1 putative citrate transporter, CitMHS family (YP_062661.1| Mg++/citrate complex transporter [Leifsonia xyli subsp. xyli str. CTCB07]; NP_599319.2| H+/citrate symporter [Corynebacterium glutamicum ATCC 13032]). pfam03600, CitMHS, Citrate transporter. InterPro: Citrate transporter.; High confidence in function and specificity; citrate transporter 3203919 5174799 CMM_2878 Clavibacter michiganensis subsp. michiganensis NCPPB 382 citrate transporter YP_001223623.1 3202468 D 443906 CDS YP_001223624.1 148274063 5173877 complement(3204043..3205512) 1 NC_009480.1 conserved membrane protein (NP_821248.1| hypothetical protein SAV74 [Streptomyces avermitilis MA-4680]; ZP_00175585.2| COG3463: Predicted membrane protein [Crocosphaera watsonii WH 8501]).; Conserved hypothetical protein; hypothetical protein 3205512 5173877 CMM_2879 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223624.1 3204043 R 443906 CDS YP_001223625.1 148274064 5174428 complement(3205613..3206044) 1 NC_009480.1 conserved hypothetical protein (YP_061782.1| hypothetical protein Lxx07570 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_822361.1| hypothetical protein SAV1186 [Streptomyces avermitilis MA-4680]).; hypothetical protein 3206044 5174428 CMM_2880 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223625.1 3205613 R 443906 CDS YP_001223626.1 148274065 5174316 3206148..3207173 1 NC_009480.1 putative transcriptional regulator, LysR family (YP_120335.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]; NP_625268.1| putative lysR-family trancsriptional regulator [Streptomyces coelicolor A3(2)]). pfam00126, HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family. pfam03466, LysR_substrate,LysR substrate binding domain. InterPro: Bacterial regulatory protein LysR family.; Specificity unclear; LysR family transcriptional regulator 3207173 5174316 CMM_2881 Clavibacter michiganensis subsp. michiganensis NCPPB 382 LysR family transcriptional regulator YP_001223626.1 3206148 D 443906 CDS YP_001223627.1 148274066 5174694 complement(3207204..3207935) 1 NC_009480.1 hypothetical protein (NP_104793.1| hypothetical protein mlr3756 [Mesorhizobium loti MAFF303099]; YP_133572.1| hypothetical protein PBPRB1925 [Photobacterium profundum SS9]).; hypothetical protein 3207935 5174694 CMM_2882 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223627.1 3207204 R 443906 CDS YP_001223628.1 148274067 5175951 3208085..3208432 1 NC_009480.1 hypothetical protein 3208432 5175951 CMM_2883 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223628.1 3208085 D 443906 CDS YP_001223629.1 148274068 5174335 complement(3208462..3209358) 1 NC_009480.1 crtEb; UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; prenyltransferase 3209358 ubiA 5174335 ubiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 prenyltransferase YP_001223629.1 3208462 R 443906 CDS YP_001223630.1 148274069 5175127 complement(3209351..3209719) 1 NC_009480.1 putative C50 carotenoid epsilon cyclase/lycopene e-cyclase isoprenoid transferase B (NP_737248.1| C50 carotenoid epsilon cyclase [Corynebacterium efficiens YS-314]; lycopene e-cyclase isoprenoid transferase B [Agromyces mediolanus]).; High confidence in function and specificity; putative C50 carotenoid epsilon cyclase 3209719 crtY2 5175127 crtY2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative C50 carotenoid epsilon cyclase YP_001223630.1 3209351 R 443906 CDS YP_001223631.1 148274070 5174222 complement(3209716..3210060) 1 NC_009480.1 putative C50 carotenoid epsilon cyclase (NP_599857.1| C50 carotenoid epsilon cyclase [Corynebacterium glutamicum ATCC 13032]; AAM94365.1| lycopene e-cyclase isoprenoid transferase A [Agromyces mediolanus]).; High confidence in function and specificity; putative C50 carotenoid epsilon cyclase 3210060 crtY1 5174222 crtY1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative C50 carotenoid epsilon cyclase YP_001223631.1 3209716 R 443906 CDS YP_001223632.1 148274071 5173765 complement(3210060..3212705) 1 NC_009480.1 putative bifunctional phytoene synthase/phytoene dehydrogenase ( N-terminal, COG1562, ERG9,Phytoene/squalene synthetase; pfam00494, SQS_PSY,Squalene/phytoene synthase. (AAM94363.1| phytoene synthase [Agromyces mediolanus]; AAK64298.1| phytoene synthase [Corynebacterium glutamicum]). C-terminal, COG1233,COG1233, Phytoene dehydrogenase and related proteins (Phytoene dehydrogenase (Phytoene desaturase). (AAM94364.1| phytoene desaturase [Agromyces mediolanus]; AAK64299.1| phytoene desaturase [Corynebacterium glutamicum]). CAROTENOID BIOSYNTHESIS; High confidence in function and specificity; putative bifunctional phytoene synthase/phytoene dehydrogenase 3212705 crtBI 5173765 crtBI Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative bifunctional phytoene synthase/phytoene dehydrogenase YP_001223632.1 3210060 R 443906 CDS YP_001223633.1 148274072 5173032 complement(3212702..3213724) 1 NC_009480.1 putative geranylgeranyl pyrophosphate synthase [Includes: Dimethylallyltransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)] (AAF65590.1| GGPP synthase [Brevibacterium linens]; YP_062473.1| geranylgeranyl pyrophosphate synthase [Leifsonia xyli subsp. xyli str. CTCB07]; AAM94362.1| geranylgeranyl pyrophosphate synthase [Agromyces mediolanus]). pfam00348,polyprenyl_synt, Polyprenyl synthetase. InterPro: Polyprenyl synthetase.; High confidence in function and specificity; putative geranylgeranyl pyrophosphate synthase 3213724 crtE 5173032 crtE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative geranylgeranyl pyrophosphate synthase YP_001223633.1 3212702 R 443906 CDS YP_001223634.1 148274073 5173455 3213817..3214401 1 NC_009480.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3214401 idiA 5173455 idiA Clavibacter michiganensis subsp. michiganensis NCPPB 382 isopentenyl-diphosphate delta-isomerase YP_001223634.1 3213817 D 443906 CDS YP_001223635.1 148274074 5174394 complement(3214474..3215352) 1 NC_009480.1 conserved hypothetical protein, putative phospholipase (NP_629464.1| hypothetical protein SCO5322 [Streptomyces coelicolor A3(2)]; NP_335532.1| hypothetical protein MT1092 [Mycobacterium tuberculosis CDC1551]). pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. hydrog_prot: hydrogenase maturation prot; Function unclear; putative phospholipase 3215352 5174394 CMM_2890 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative phospholipase YP_001223635.1 3214474 R 443906 CDS YP_001223636.1 148274075 5174781 complement(3215480..3216064) 1 NC_009480.1 putative transcription regulator, MarR family (YP_062474.1| transcriptional regulator, MarR family [Leifsonia xyli subsp. xyli str. CTCB07]; CAF19334.1| transcriptional regulator, MarR family [Corynebacterium glutamicum ATCC 13032]; NP_625140.1| putative marR-family transcriptional regulator [Streptomyces coelicolor A3(2)). pfam01047, MarR, MarR family.; Specificity unclear; MarR family transcriptional regulator 3216064 5174781 CMM_2891 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MarR family transcriptional regulator YP_001223636.1 3215480 R 443906 CDS YP_001223637.1 148274076 5174284 3216142..3218220 1 NC_009480.1 putative RND family transporter (Q53902|MMLA_STRCO Putative membrane protein actII-3; YP_118784.1| putative membrane protein [Nocardia farcinica IFM 10152]). pfam03176, MMPL, MMPL family. Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport. InterPro: HMGCR/Patched 5TM box.; Conserved hypothetical protein; RND family transporter 3218220 5174284 CMM_2892 Clavibacter michiganensis subsp. michiganensis NCPPB 382 RND family transporter YP_001223637.1 3216142 D 443906 CDS YP_001223638.1 148274077 5174896 3218297..3219049 1 NC_009480.1 putative short chain dehydrogenase/oxidoreductase (NP_465699.1| ; ZP_00103824.1| COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Desulfitobacterium hafniense]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases.; Function unclear; putative short chain dehydrogenase/oxidoreductase 3219049 5174896 CMM_2893 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short chain dehydrogenase/oxidoreductase YP_001223638.1 3218297 D 443906 CDS YP_001223639.1 148274078 5175017 complement(3219046..3219654) 1 NC_009480.1 putative transcriptional regulator, TetR family (ZP_00189647.3| COG1309: Transcriptional regulator [Kineococcus radiotolerans SRS30216]; NP_963085.1| hypothetical protein MAP4151c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00440, TetR_N, Bacterial regulatory proteins, tetR family. InterPro: Bacterial regulatory proteins TetR family.; Specificity unclear; TetR family transcriptional regulator 3219654 5175017 CMM_2894 Clavibacter michiganensis subsp. michiganensis NCPPB 382 TetR family transcriptional regulator YP_001223639.1 3219046 R 443906 CDS YP_001223640.1 148274079 5173540 3219715..3220203 1 NC_009480.1 conserved hypothetical protein (NP_245758.1| unknown [Pasteurella multocida]; NP_758064.1| conserved hypothetical protein [Mycoplasma penetrans HF-2]).; hypothetical protein 3220203 5173540 CMM_2895 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223640.1 3219715 D 443906 CDS YP_001223641.1 148274080 5173757 complement(3220506..3221165) 1 NC_009480.1 hypothetical membrane protein (NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00120603.2| hypothetical protein Blon03000461 [Bifidobacterium longum DJO10A]).; hypothetical protein 3221165 5173757 CMM_2896 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223641.1 3220506 R 443906 CDS YP_001223642.1 148274081 5175375 complement(3221309..3222004) 1 NC_009480.1 hypothetical membrane protein (NP_821188.1| putative membrane protein [Streptomyces avermitilis MA-4680]; ZP_00120603.2| hypothetical protein Blon03000461 [Bifidobacterium longum DJO10A]).; hypothetical protein 3222004 5175375 CMM_2897 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223642.1 3221309 R 443906 CDS YP_001223643.1 148274082 5173813 complement(3222082..3223197) 1 NC_009480.1 putative L-alanine dehydrogenase (NP_827683.1| putative L-alanine dehydrogenase [Streptomyces avermitilis MA-4680]; AAM44187.1| L-alanine dehydrogenase [Mycobacterium smegmatis]). pfam05222, AlaDh_PNT_N,Alanine dehydrogenase/PNT, N-terminal domain. pfam01262,AlaDh_PNT_C, Alanine dehydrogenase/PNT, C-terminal domain. InterPro: Alanine dehydrogenase and pyridine nucleotide transhydrogenase.; High confidence in function and specificity; putative L-alanine dehydrogenase 3223197 aldA 5173813 aldA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative L-alanine dehydrogenase YP_001223643.1 3222082 R 443906 CDS YP_001223644.1 148274083 5173588 3223363..3223857 1 NC_009480.1 putative leucine-responsive regulatory protein,AsnC family (NP_337354.1| transcriptional regulator, AsnC family [Mycobacterium tuberculosis CDC1551]; ZP_00226252.1| COG1522: Transcriptional regulators [Kineococcus radiotolerans SRS30216]). pfam01037,AsnC_trans_reg, AsnC family. The AsnC family is a family of similar bacterial transcription regulatory proteins. InterPro: Bacterial regulatory proteins AsnC family.; Specificity unclear; leucine-responsive regulatory protein 3223857 5173588 CMM_2899 Clavibacter michiganensis subsp. michiganensis NCPPB 382 leucine-responsive regulatory protein YP_001223644.1 3223363 D 443906 CDS YP_001223645.1 148274084 5174678 complement(3223871..3224476) 1 NC_009480.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 3224476 dcd 5174678 dcd Clavibacter michiganensis subsp. michiganensis NCPPB 382 deoxycytidine triphosphate deaminase YP_001223645.1 3223871 R 443906 CDS YP_001223646.1 148274085 5175367 3224825..3227245 1 NC_009480.1 hypothetical protein 3227245 5175367 CMM_2901 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223646.1 3224825 D 443906 CDS YP_001223647.1 148274086 5174386 complement(3228028..3228462) 1 NC_009480.1 hypothetical protein 3228462 5174386 CMM_2902 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223647.1 3228028 R 443906 CDS YP_001223648.1 148274087 5174109 3228643..3229398 1 NC_009480.1 putative ABC transporter, ATP-binding protein (NP_821704.1| putative ABC transporter ATP-binding protein [Streptomyces avermitilis MA-4680]; NP_763672.1| ABC transporter (ATP-binding protein) [Staphylococcus epidermidis ATCC 12228]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative ABC transporter, ATP-binding protein 3229398 5174109 CMM_2903 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative ABC transporter, ATP-binding protein YP_001223648.1 3228643 D 443906 CDS YP_001223649.1 148274088 5174835 3229398..3230696 1 NC_009480.1 hypothetical membrane protein (NP_939325.1| Putative membrane protein [Corynebacterium diphtheriae NCTC 13129]; YP_054886.1| hypothetical protein PPA0171 [Propionibacterium acnes KPA171202]).; hypothetical protein 3230696 5174835 CMM_2904 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223649.1 3229398 D 443906 CDS YP_001223650.1 148274089 5173993 3230693..3231316 1 NC_009480.1 Hypothetical protein; hypothetical protein 3231316 5173993 CMM_2905 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223650.1 3230693 D 443906 CDS YP_001223651.1 148274090 5172951 complement(3231313..3232077) 1 NC_009480.1 putative transcriptional regulator, GntR family (ZP_00051637.1| COG2186: Transcriptional regulators [Magnetospirillum magnetotacticum]; NP_739032.1| putative transcription factor [Corynebacterium efficiens YS-314]). pfam00392, GntR, Bacterial regulatory proteins, gntR family. InterPro: Bacterial regulatory proteins GntR family.; Specificity unclear; GntR family transcriptional regulator 3232077 5172951 CMM_2906 Clavibacter michiganensis subsp. michiganensis NCPPB 382 GntR family transcriptional regulator YP_001223651.1 3231313 R 443906 CDS YP_001223652.1 148274091 5173639 3232226..3232744 1 NC_009480.1 putative gluconokinase (Gluconate kinase 2)(NP_625954.1| putative gluconokinase [Streptomyces coelicolor A3(2)]; ZP_00291960.1| COG3265: Gluconate kinase [Thermobifida fusca]).; Specificity unclear; putative gluconokinase 3232744 gntK 5173639 gntK Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative gluconokinase YP_001223652.1 3232226 D 443906 CDS YP_001223653.1 148274092 5172955 3232827..3234227 1 NC_009480.1 putative gluconate permease, GntP family (NP_602098.1| putative gluconate permease [Corynebacterium glutamicum ATCC 13032]; NP_283240.1| putative gluconate permease [Neisseria meningitidis Z2491]). , pfam02447,GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake.; High confidence in function and specificity; gluconate permease 3234227 gntP 5172955 gntP Clavibacter michiganensis subsp. michiganensis NCPPB 382 gluconate permease YP_001223653.1 3232827 D 443906 CDS YP_001223654.1 148274093 5174951 complement(3234224..3234799) 1 NC_009480.1 putative pyridoxamine 5-phosphate oxidase (NP_681121.1| pyridoxamine 5'-phosphate oxidase [Thermosynechococcus elongatus BP-1]; NP_825001.1| putative oxidase [Streptomyces avermitilis MA-4680]). pfam01243, Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase. InterPro: Pyridoxamine 5-phosphate oxidase.; Specificity unclear; putative pyridoxamine 5-phosphate oxidase 3234799 5174951 CMM_2909 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative pyridoxamine 5-phosphate oxidase YP_001223654.1 3234224 R 443906 CDS YP_001223655.1 148274094 5173038 complement(3234844..3235653) 1 NC_009480.1 putative DNA glycosylase/endonuclease VIII (NP_939193.1| Putative endonuclease [Corynebacterium diphtheriae NCTC 13129]; YP_062887.1| DNA glycosylase [Leifsonia xyli subsp. xyli str. CTCB07]). pfam01149,Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase N-terminal domain. Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. pfam06831, H2TH, Formamidopyrimidine-DNA glycosylase H2TH domain.; Specificity unclear; putative DNA glycosylase/endonuclease VIII 3235653 5173038 CMM_2910 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA glycosylase/endonuclease VIII YP_001223655.1 3234844 R 443906 CDS YP_001223656.1 148274095 5174544 complement(3235699..3236730) 1 NC_009480.1 Hypothetical protein; hypothetical protein 3236730 5174544 CMM_2911 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223656.1 3235699 R 443906 CDS YP_001223657.1 148274096 5173019 3237001..3237747 1 NC_009480.1 putative short-chain dehydrogenase (NP_793827.1| oxidoreductase, short-chain dehydrogenase/reductase family [Pseudomonas syringae pv. tomato str. DC3000]; NP_631846.1| putative oxidoreductase. [Streptomyces coelicolor A3(2)]). pfam00106, adh_short, short chain dehydrogenase. This family contains a wide variety of dehydrogenases. InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily.; Function unclear; putative short-chain dehydrogenase/oxidoreductase 3237747 5173019 CMM_2912 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative short-chain dehydrogenase/oxidoreductase YP_001223657.1 3237001 D 443906 CDS YP_001223658.1 148274097 5175674 3237806..3238822 1 NC_009480.1 putative oxidoreductase (NP_626533.1| putative oxidoreductase [Streptomyces coelicolor A3(2)]; ZP_00294380.1| COG0673: Predicted dehydrogenases and related proteins [Thermobifida fusca]). pfam01408,GFO_IDH_MocA, Oxidoreductase family, NAD-binding Rossmann fold. pfam02894, GFO_IDH_MocA_C, Oxidoreductase family, C-terminal alpha/beta domain.; Function unclear; putative oxidoreductase 3238822 5175674 CMM_2913 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative oxidoreductase YP_001223658.1 3237806 D 443906 CDS YP_001223659.1 148274098 5174155 3238887..3239504 1 NC_009480.1 conserved hypothetical protein, putative reductase (NP_625187.1| putative secreted protein [Streptomyces coelicolor A3(2)]; NP_217570.1| hypothetical protein Rv3054c [Mycobacterium tuberculosis H37Rv]). pfam03358,FMN_red, NADPH-dependent FMN reductase. thiE: thiamine-phosphate pyrophosphorylas; Function unclear; putative reductase 3239504 5174155 CMM_2914 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative reductase YP_001223659.1 3238887 D 443906 CDS YP_001223660.1 148274099 5175164 complement(3239594..3240769) 1 NC_009480.1 putative Zn-dependant dehydrogenase (NP_737735.1| putative glutathione-dependent aldehyde dehydrogenase [Corynebacterium efficiens YS-314]; NP_962197.1| hypothetical protein MAP3263c [Mycobacterium avium subsp. paratuberculosis str. k10]). pfam00107, ADH_zinc_N, Zinc-binding dehydrogenase.; Function unclear; putative Zn-dependant dehydrogenase 3240769 5175164 CMM_2915 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative Zn-dependant dehydrogenase YP_001223660.1 3239594 R 443906 CDS YP_001223661.1 148274100 5174411 complement(3241144..3241494) 1 NC_009480.1 hypothetical protein 3241494 5174411 CMM_2916 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223661.1 3241144 R 443906 CDS YP_001223662.1 148274101 5175800 complement(3241651..3241974) 1 NC_009480.1 hypothetical protein (YP_062476.1| hypothetical protein Lxx15660 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 3241974 5175800 CMM_2917 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223662.1 3241651 R 443906 CDS YP_001223663.1 148274102 5175265 3242226..3242429 1 NC_009480.1 hypothetical protein 3242429 5175265 CMM_2918 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223663.1 3242226 D 443906 CDS YP_001223664.1 148274103 5175971 3242535..3243257 1 NC_009480.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 3243257 deoC 5175971 deoC Clavibacter michiganensis subsp. michiganensis NCPPB 382 deoxyribose-phosphate aldolase YP_001223664.1 3242535 D 443906 CDS YP_001223665.1 148274104 5173946 3243257..3244552 1 NC_009480.1 catalyzes the removal of amino acids from the N termini of peptides; putative aminopeptidase 2 3244552 5173946 CMM_2920 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aminopeptidase 2 YP_001223665.1 3243257 D 443906 CDS YP_001223666.1 148274105 5175705 complement(3244634..3245347) 1 NC_009480.1 conserved hypothetical protein (NP_825954.1| hypothetical protein SAV4777 [Streptomyces avermitilis MA-4680]; AAS20121.1| hypothetical protein [Arthrobacter aurescens]). pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function.; hypothetical protein 3245347 5175705 CMM_2921 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223666.1 3244634 R 443906 CDS YP_001223667.1 148274106 5173876 3245403..3246053 1 NC_009480.1 conserved hypothetical protein, putative dienelactone hydrolase (P46209|USF_AQUPY USF PROTEIN [Aquifex pyrophilus]; ZP_00211570.1| COG0412: Dienelactone hydrolase and related enzymes [Burkholderia cepacia R18194]). pfam01738, DLH, Dienelactone hydrolase family.; Family membership; putative dienelactone hydrolase 3246053 5173876 CMM_2922 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative dienelactone hydrolase YP_001223667.1 3245403 D 443906 CDS YP_001223668.1 148274107 5175370 3246154..3246573 1 NC_009480.1 hypothetical membrane protein (YP_063203.1| hypothetical protein Lxx24840 [Leifsonia xyli subsp. xyli str. CTCB07]; YP_120716.1| hypothetical protein nfa45010 [Nocardia farcinica IFM 10152]).; hypothetical protein 3246573 5175370 CMM_2923 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223668.1 3246154 D 443906 CDS YP_001223669.1 148274108 5173373 3246688..3247383 1 NC_009480.1 Hypothetical protein; hypotheical membrane protein 3247383 5173373 CMM_2924 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypotheical membrane protein YP_001223669.1 3246688 D 443906 CDS YP_001223670.1 148274109 5172999 complement(3247415..3248716) 1 NC_009480.1 conserved hypothetical protein, putative helicase (NP_813041.1| putative helicase [Bacteroides thetaiotaomicron VPI-5482]; NP_904413.1| TPR domain protein [Porphyromonas gingivalis W83]). cd00009, AAA, AAA-superfamily of ATPases associated with a wide variety of cellular activities, including membrane fusion,proteolysis, and DNA replication.; Family membership; putative helicase 3248716 5172999 CMM_2925 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative helicase YP_001223670.1 3247415 R 443906 CDS YP_001223671.1 148274110 5174134 3248847..3249866 1 NC_009480.1 hypothetical protein (YP_063208.1| hypothetical protein Lxx24950 [Leifsonia xyli subsp. xyli str. CTCB07]).; hypothetical protein 3249866 5174134 CMM_2926 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223671.1 3248847 D 443906 CDS YP_001223672.1 148274111 5173848 3249982..3250410 1 NC_009480.1 conserved hypothetical protein (YP_119319.1| hypothetical protein nfa31080 [Nocardia farcinica IFM 10152]; NP_631048.1| conserved hypothetical protein SC8F11.09. [Streptomyces coelicolor A3(2)]). pfam00903,Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.; hypothetical protein 3250410 5173848 CMM_2927 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223672.1 3249982 D 443906 CDS YP_001223673.1 148274112 5175678 complement(3250434..3251276) 1 NC_009480.1 putative iron-siderophore ABC transporter, ATP-binding protein (NP_827669.1| putative iron(III) dicitrate transport system ATP-binding protein [Streptomyces avermitilis MA-4680]; ZP_00292631.1| COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Thermobifida fusca]). pfam00005, ABC_tran, ABC transporter. InterPro: AAA ATPase superfamily.; Specificity unclear; putative iron-siderophore ABC transporter, ATP-binding protein 3251276 fecE 5175678 fecE Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter, ATP-binding protein YP_001223673.1 3250434 R 443906 CDS YP_001223674.1 148274113 5173270 complement(3251311..3252417) 1 NC_009480.1 putative iron-siderophore ABC transporter, permease component (NP_396248.1| AGR_pAT_451p [Agrobacterium tumefaciens str. C58]; CAF19213.1| cobalamin/Fe3+-siderophores transport system, permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032,FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporter,permease component 3252417 fecD2 5173270 fecD2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,permease component YP_001223674.1 3251311 R 443906 CDS YP_001223675.1 148274114 5173214 complement(3252414..3253472) 1 NC_009480.1 putative iron-siderophore ABC transporter, permease component (NP_535686.1| ABC transporter, membrane spanning protein [iron] [Agrobacterium tumefaciens str. C58]; CAF19214.1| cobalamin/ Fe3+-siderophores transport system,permease component [Corynebacterium glutamicum ATCC 13032]). , pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.; Specificity unclear; putative iron-siderophore ABC transporter,permease component 3253472 fecC2 5173214 fecC2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,permease component YP_001223675.1 3252414 R 443906 CDS YP_001223676.1 148274115 5173175 3253575..3254579 1 NC_009480.1 putative iron-siderophore ABC transporter,substrate-binding protein (CAF19960.1| ABC-type cobalamin/Fe3+-siderophores transport system secreted component [Corynebacterium glutamicum ATCC 13032]; NP_789016.1| putative iron-siderophore binding lipoprotein [Tropheryma whipplei TW08/27]). , pfam01497, Peripla_BP_2,Periplasmic binding protein. This family includes bacterial periplasmic binding proteins. Several of which are involved in iron transport. InterPro: Periplasmic binding protein.; Specificity unclear; putative iron-siderophore ABC transporter,substrate-binding protein 3254579 fecB2 5173175 fecB2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative iron-siderophore ABC transporter,substrate-binding protein YP_001223676.1 3253575 D 443906 CDS YP_001223677.1 148274116 5173013 3254708..3255382 1 NC_009480.1 conserved membrane protein (ZP_00135206.2| COG0477: Permeases of the major facilitator superfamily [Actinobacillus pleuropneumoniae serovar 1 str. 4074]; AAO81566.1| conserved hypothetical protein [Enterococcus faecalis V583]).; hypothetical protein 3255382 5173013 CMM_2932 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223677.1 3254708 D 443906 CDS YP_001223678.1 148274117 5174751 complement(3255416..3257395) 1 NC_009480.1 conserved membrane protein, putative copper export protein (YP_063209.1| hypothetical protein Lxx24960 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00226005.1| COG3336: Predicted membrane protein [Kineococcus radiotolerans SRS30216]; ZP_00293713.1| COG3336: Predicted membrane protein [Thermobifida fusca]). two different domains. N-terminal: pfam05425, CopD, Copper resistance protein D; COG1276, PcoD, Putative copper export protein. C-terminal: COG3336 Predicted membrane protein.; Function unclear; membrane protein, putative copper export protein 3257395 5174751 CMM_2933 Clavibacter michiganensis subsp. michiganensis NCPPB 382 membrane protein, putative copper export protein YP_001223678.1 3255416 R 443906 CDS YP_001223679.1 148274118 5173147 complement(3257527..3257814) 1 NC_009480.1 putative DNA-binding protein HU (DNA-binding protein II) (YP_063210.1| DNA-binding HU protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787244.1| DNA-binding protein HU [Tropheryma whipplei str. Twist]; NP_826304.1| putative DNA-binding protein Hu 1 [Streptomyces avermitilis MA-4680]). pfam00216,Bac_DNA_binding, Bacterial DNA-binding protein.; Function unclear; putative DNA-binding protein HU 3257814 hupB 5173147 hupB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA-binding protein HU YP_001223679.1 3257527 R 443906 CDS YP_001223680.1 148274119 5174512 complement(3257946..3258251) 1 NC_009480.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3258251 rpsN 5174512 rpsN Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S14 YP_001223680.1 3257946 R 443906 CDS YP_001223681.1 148274120 5173972 complement(3258254..3258421) 1 NC_009480.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 3258421 rpmG 5173972 rpmG Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L33 YP_001223681.1 3258254 R 443906 CDS YP_001223682.1 148274121 5175336 complement(3258421..3258657) 1 NC_009480.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3258657 rpmB 5175336 rpmB Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L28 YP_001223682.1 3258421 R 443906 CDS YP_001223683.1 148274122 5174934 complement(3258872..3259321) 1 NC_009480.1 putative ferric uptake regulator, Fur family (YP_063214.1| ferric uptake regulator, Fur family [Leifsonia xyli subsp. xyli str. CTCB07]; NP_696299.1| probable metal uptake regulator; Specificity unclear; ferric uptake regulator family protein 3259321 furB 5174934 furB Clavibacter michiganensis subsp. michiganensis NCPPB 382 ferric uptake regulator family protein YP_001223683.1 3258872 R 443906 CDS YP_001223684.1 148274123 5174337 complement(3259318..3260244) 1 NC_009480.1 putative metal ABC transporter, permease component (YP_063215.1| ABC transporter, permease protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055329.1| ABC-type transporter, permease components [Propionibacterium acnes KPA171202]). pfam00950, ABC-3, ABC 3 transport family.; Specificity unclear; putative metal ABC transporter, permease component 3260244 5174337 CMM_2939 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, permease component YP_001223684.1 3259318 R 443906 CDS YP_001223685.1 148274124 5175257 complement(3260241..3261116) 1 NC_009480.1 putative metal ABC transporter, ATP-binding protein (YP_063216.1| ABC transporter, ATP-binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_116650.1| putative ABC transporter ATP-binding protein [Nocardia farcinica IFM 10152]). pfam00005, ABC_tran, ABC transporter.; Specificity unclear; putative metal ABC transporter, ATP-binding protein 3261116 5175257 CMM_2940 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, ATP-binding protein YP_001223685.1 3260241 R 443906 CDS YP_001223686.1 148274125 5174474 complement(3261113..3262066) 1 NC_009480.1 putative metal ABC transporter, substrate-binding protein (YP_063217.1| ABC transporter, solute binding protein [Leifsonia xyli subsp. xyli str. CTCB07]; YP_055331.1| solute binding protein [Propionibacterium acnes KPA171202]). pfam01297, SBP_bac_9, Periplasmic solute binding protein family.; Specificity unclear; putative metal ABC transporter, substrate-binding protein 3262066 5174474 CMM_2941 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative metal ABC transporter, substrate-binding protein YP_001223686.1 3261113 R 443906 CDS YP_001223687.1 148274126 5174283 complement(3262136..3263536) 1 NC_009480.1 putative 2-keto-acid dehydrogenase,dihydrolipoamide acetyltransferase E2 component (YP_063218.1| dihydrolipoamide acyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825555.1| putative dihydrolipoamide acyltransferase component [Streptomyces avermitilis MA-4680]). pfam00364, Biotin_lipoyl, Biotin-requiring enzyme. pfam02817, E3_binding, e3 binding domain. This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit. pfam00198, 2-oxoacid_dh, 2-oxoacid dehydrogenases acyltransferase (catalytic domain). These proteins contain one to three copies of a lipoyl binding domain followed by the catalytic domain.; Specificity unclear; branched-chain alpha-keto acid dehydrogenase subunit E2 3263536 5174283 CMM_2942 Clavibacter michiganensis subsp. michiganensis NCPPB 382 branched-chain alpha-keto acid dehydrogenase subunit E2 YP_001223687.1 3262136 R 443906 CDS YP_001223688.1 148274127 5173597 complement(3263577..3264632) 1 NC_009480.1 putative 2-keto acid dehydrogenase, dehydrogenase E1 beta component (YP_063219.1| pyruvate dehydrogenase E1 component, beta subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628005.1| putative branched-chain alpha keto acid dehydrogenase E1 beta subunit [Streptomyces coelicolor A3(2)]). pfam02779, Transket_pyr,Transketolase, pyridine binding domain. pfam02780,Transketolase_C, Transketolase, C-terminal domain. The C-terminal domain of transketolase has been proposed as a regulatory molecule binding site. InterPro: Transketolase.; Specificity unclear; putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component 3264632 5173597 CMM_2943 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component YP_001223688.1 3263577 R 443906 CDS YP_001223689.1 148274128 5175714 complement(3264629..3265741) 1 NC_009480.1 putative 2-keto acid dehydrogenase, dehydrogenase E1 beta component (YP_063220.1| pyruvate dehydrogenase E1 component, alpha subunit [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628006.1| putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit [Streptomyces coelicolor A3(2)]). , pfam00676, E1_dh, Dehydrogenase E1 component. This family uses thiamine pyrophosphate as a cofactor.; Specificity unclear; putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component 3265741 5175714 CMM_2944 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative 2-keto acid dehydrogenase,dehydrogenase E1 beta component YP_001223689.1 3264629 R 443906 CDS YP_001223690.1 148274129 5174774 complement(3265751..3266866) 1 NC_009480.1 putative histidinol-phosphate aminotransferase 2 (YP_063221.1| histidinol-phosphate aminotransferase 2 [Leifsonia xyli subsp. xyli str. CTCB07]; Q82FJ1|PATR_STRAW Putative phenylalanine aminotransferase). pfam00155, Aminotran_1_2,Aminotransferase class I and II.; Specificity unclear; putative aminotransferase 3266866 hisC2 5174774 hisC2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative aminotransferase YP_001223690.1 3265751 R 443906 CDS YP_001223691.1 148274130 5173605 3266937..3267332 1 NC_009480.1 conserved membrane protein (YP_063222.1| hypothetical protein Lxx25090 [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00293541.1| COG1950: Predicted membrane protein [Thermobifida fusca]). pfam04020, DUF360, Membrane protein of unknown function.; Conserved hypothetical protein; hypothetical protein 3267332 5173605 CMM_2946 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223691.1 3266937 D 443906 CDS YP_001223692.1 148274131 5174893 complement(3267341..3268615) 1 NC_009480.1 hypothetical protein gidA: glucose-inhibited division protein; hypothetical protein 3268615 5174893 CMM_2947 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223692.1 3267341 R 443906 CDS YP_001223693.1 148274132 5175092 complement(3268612..3268938) 1 NC_009480.1 hypothetical protein 3268938 5175092 CMM_2948 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223693.1 3268612 R 443906 CDS YP_001223694.1 148274133 5175727 3269071..3269598 1 NC_009480.1 putative protein-tyrosine-phosphatase (Small acidic phosphotyrosine protein phosphatase) (P53433|PTPA_STRCO Low molecular weight protein-tyrosine-phosphatase (PTPase) (Small, acidic phosphotyrosine protein phosphatase); ZP_00292310.1| COG0394: Protein-tyrosine- phosphatase [Thermobifida fusca]). pfam01451, LMWPc, Low molecular weight phosphotyrosine protein phosphatase.; Function unclear; putative protein-tyrosine-phosphatase 3269598 5175727 CMM_2949 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative protein-tyrosine-phosphatase YP_001223694.1 3269071 D 443906 CDS YP_001223695.1 148274134 5174863 3269612..3270994 1 NC_009480.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 3270994 purB 5174863 purB Clavibacter michiganensis subsp. michiganensis NCPPB 382 adenylosuccinate lyase YP_001223695.1 3269612 D 443906 CDS YP_001223696.1 148274135 5173229 complement(3271053..3271322) 1 NC_009480.1 hypothetical membrane protein (YP_063224.1| hypothetical protein Lxx25110 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_787867.1| hypothetical protein TWT739 [Tropheryma whipplei str. Twist]).; hypothetical protein 3271322 5173229 CMM_2951 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223696.1 3271053 R 443906 CDS YP_001223697.1 148274136 5174118 complement(3271325..3271981) 1 NC_009480.1 conserved membrane protein (ZP_00347695.1| COG3247: Uncharacterized conserved protein [Pseudomonas aeruginosa UCBPP-PA14]; NP_879989.1| putative membrane protein [Bordetella pertussis Tohama I]).; Conserved hypothetical protein; hypothetical protein 3271981 5174118 CMM_2952 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223697.1 3271325 R 443906 CDS YP_001223698.1 148274137 5173253 3272339..3273223 1 NC_009480.1 putative polyphosphate glucokinase (Polyphosphate-glucose phosphotransferase) (YP_061973.1| glucokinase [Leifsonia xyli subsp. xyli str. CTCB07]; BAC84981.1| polyphosphate-dependent glucokinase [Microlunatus phosphovorus]). , pfam00480, ROK, ROK family.; High confidence in function and specificity; putative polyphosphate glucokinase 3273223 ppgK2 5173253 ppgK2 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative polyphosphate glucokinase YP_001223698.1 3272339 D 443906 CDS YP_001223699.1 148274138 5175939 3273314..3274429 1 NC_009480.1 putative glycerate kinase (YP_061712.1| glycerate kinase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_931292.1| Glycerate kinase 2 [Photorhabdus luminescens subsp. laumondii TTO1]). pfam02595, Gly_kinase, Glycerate kinase family.; High confidence in function and specificity; putative glycerate kinase 3274429 5175939 CMM_2954 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycerate kinase YP_001223699.1 3273314 D 443906 CDS YP_001223700.1 148274139 5175601 complement(3274446..3275672) 1 NC_009480.1 putative glycosyl transferase (NP_789728.1| putative glycosyltransferase [Tropheryma whipplei TW08/27]; ZP_00058815.1| COG0438: Glycosyltransferase [Thermobifida fusca]). , pfam00534, Glycos_transf_1,Glycosyl transferases group 1. Members of this family transfer activated sugars to a variety of substrates,including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP,ADP, GDP or CMP linked sugars. InterPro: Glycosyl transferases group 1.; Function unclear; putative glycosyl transferase 3275672 5175601 CMM_2955 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative glycosyl transferase YP_001223700.1 3274446 R 443906 CDS YP_001223701.1 148274140 5175452 3275841..3276230 1 NC_009480.1 putative transcriptional regulator, MerR family (ZP_00225271.3| COG0789: Predicted transcriptional regulators [Kineococcus radiotolerans SRS30216]; NP_627487.1| putative merR-family transcriptional regulator [Streptomyces coelicolor A3(2)]). pfam00376,MerR, MerR family regulatory protein.; Hypothetical protein; hypothetical protein 3276230 5175452 CMM_2956 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223701.1 3275841 D 443906 CDS YP_001223702.1 148274141 5173932 3276287..3277912 1 NC_009480.1 putative peptide chain release factor 3 (RF-3)(YP_121111.1| putative peptide chain release factor [Nocardia farcinica IFM 10152]; ZP_00292654.1| COG4108: Peptide chain release factor RF-3 [Thermobifida fusca]). pfam00009, GTP_EFTU, Elongation factor Tu GTP binding domain. pfam03144, GTP_EFTU_D2, Elongation factor Tu domain 2.; High confidence in function and specificity; putative peptide chain release factor 3 3277912 prfC 5173932 prfC Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative peptide chain release factor 3 YP_001223702.1 3276287 D 443906 CDS YP_001223703.1 148274142 5173866 3278067..3278372 1 NC_009480.1 conserved hypothetical protein (YP_062896.1| hypothetical protein Lxx20930 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_691705.1| hypothetical protein OB0784 [Oceanobacillus iheyensis HTE831]; NP_738809.1| conserved hypothetical protein [Corynebacterium efficiens YS-314]). pfam05495, zf-CHY, CHY zinc finger. This family of domains are likely to bind to zinc ions. They contain many conserved cysteine and histidine residues. We have named this domain after the N-terminal motif CXHY.; Function unclear; hypothetical protein 3278372 5173866 CMM_2958 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223703.1 3278067 D 443906 CDS YP_001223704.1 148274143 5174719 complement(3278482..3279861) 1 NC_009480.1 putative replicative DNA helicase (YP_063226.1| replicative DNA helicase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_628097.1| putative replicative DNA helicase [Streptomyces coelicolor A3(2)]). pfam00772, DnaB, DnaB-like helicase N terminal domain. pfam03796, DnaB_C, DnaB-like helicase C terminal domain. InterPro: DnaB helicase.; High confidence in function and specificity; putative replicative DNA helicase 3279861 dnaB 5174719 dnaB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative replicative DNA helicase YP_001223704.1 3278482 R 443906 CDS YP_001223705.1 148274144 5175453 complement(3280318..3280770) 1 NC_009480.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 3280770 rplI 5175453 rplI Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L9 YP_001223705.1 3280318 R 443906 CDS YP_001223706.1 148274145 5174555 complement(3280782..3281045) 1 NC_009480.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 3281045 rpsR 5174555 rpsR Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S18 YP_001223706.1 3280782 R 443906 CDS YP_001223707.1 148274146 5175849 complement(3281082..3281633) 1 NC_009480.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein 3281633 ssb 5175849 ssb Clavibacter michiganensis subsp. michiganensis NCPPB 382 single-stranded DNA-binding protein YP_001223707.1 3281082 R 443906 CDS YP_001223708.1 148274147 5175696 complement(3281637..3282101) 1 NC_009480.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 3282101 rpsF 5175696 rpsF Clavibacter michiganensis subsp. michiganensis NCPPB 382 30S ribosomal protein S6 YP_001223708.1 3281637 R 443906 CDS YP_001223709.1 148274148 5173088 complement(3282265..3283695) 1 NC_009480.1 putative tRNA nucleotidyltransferase/ poly(A)nucleotidyltransferase (YP_063231.1| poly(A) polymerase; tRNA nucleotidyltransferase [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825476.1| putative RNA nucleotidyltransferase [Streptomyces avermitilis MA-4680]; NP_787928.1| poly(A) polymerase [Tropheryma whipplei str. Twist]). pfam01743, PolyA_pol, Poly A polymerase family. This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase,which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. pfam01966,HD, HD domain. HD domains are metal dependent phosphohydrolases.; Specificity unclear; putative RNA nucleotidyltransferase 3283695 pcnA 5173088 pcnA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNA nucleotidyltransferase YP_001223709.1 3282265 R 443906 CDS YP_001223710.1 148274149 5175572 3283789..3286086 1 NC_009480.1 conserved hypothetical protein (YP_063232.1| membrane protein [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00291602.1| hypothetical protein Tfus02002926 [Thermobifida fusca]); hypothetical protein 3286086 5175572 CMM_2965 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223710.1 3283789 D 443906 CDS YP_001223711.1 148274150 5175409 3286123..3287751 1 NC_009480.1 conserved membrane protein, MOP family (YP_063233.1| hypothetical protein Lxx25210 [Leifsonia xyli subsp. xyli str. CTCB07]; NP_789730.1| conserved integral membrane protein (possible virulence factor)[Tropheryma whipplei TW08/27]). pfam03023, MVIN,MviN-like protein.; Function unclear; MOP family membrane protein 3287751 5175409 CMM_2966 Clavibacter michiganensis subsp. michiganensis NCPPB 382 MOP family membrane protein YP_001223711.1 3286123 D 443906 CDS YP_001223712.1 148274151 5174874 3287908..3288945 1 NC_009480.1 putative thioredoxin reductase (YP_063234.1| thioredoxin-disulfide reductase [Leifsonia xyli subsp. xyli str. CTCB07]; Q05741|TRXB_STRCL Thioredoxin reductase (TRXR)). , pfam00070, Pyr_redox, Pyridine nucleotide-disulphide oxidoreductase.; High confidence in function and specificity; putative thioredoxin reductase 3288945 trxB1 5174874 trxB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin reductase YP_001223712.1 3287908 D 443906 CDS YP_001223713.1 148274152 5175941 3289013..3289336 1 NC_009480.1 putative thioredoxin (YP_063235.1| thioredoxin [Leifsonia xyli subsp. xyli str. CTCB07]; Q05739|THIO_STRCL Thioredoxin (TRX)). pfam00085,Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond.; High confidence in function and specificity; putative thioredoxin 3289336 trxA 5175941 trxA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative thioredoxin YP_001223713.1 3289013 D 443906 CDS YP_001223714.1 148274153 5174325 3289507..3290829 1 NC_009480.1 putative transcriptional regulator containing an aminotransferase domain (YP_063236.1| valine-pyruvate aminotransferase [Leifsonia xyli subsp. xyli str. CTCB07]; ZP_00294408.1| COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Thermobifida fusca]). pfam00155, Aminotran_1_2,Aminotransferase class I and II.; Function unclear; transcriptional regulator 3290829 5174325 CMM_2969 Clavibacter michiganensis subsp. michiganensis NCPPB 382 transcriptional regulator YP_001223714.1 3289507 D 443906 CDS YP_001223715.1 148274154 5174665 3290873..3291838 1 NC_009480.1 putative D-alanine-D-alanine ligase (D-alanylalanine synthetase) (ZP_00057905.1| COG1181: D-alanine-D-alanine ligase and related ATP-grasp enzymes [Thermobifida fusca]; O66806|DDL_AQUAE D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase)). pfam01820, Dala_Dala_ligas, D-ala D-ala ligase. This family contains D-alanine--D-alanine ligase enzymes EC:6.3.2.4. InterPro: D-alanine--D-alanine ligase.; High confidence in function and specificity; putative D-alanine-D-alanine ligase 3291838 ddlB 5174665 ddlB Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative D-alanine-D-alanine ligase YP_001223715.1 3290873 D 443906 CDS YP_001223716.1 148274155 5175168 complement(3291891..3292880) 1 NC_009480.1 putative chromosome partitioning protein (YP_063237.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_302727.1| putative cell division protein [Mycobacterium leprae TN]). pfam02195,ParBc, ParB-like nuclease domain. , InterPro: ParB-like partition protein.; High confidence in function and specificity; putative chromosome partitioning protein 3292880 parB1 5175168 parB1 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chromosome partitioning protein YP_001223716.1 3291891 R 443906 CDS YP_001223717.1 148274156 5175456 complement(3292880..3293761) 1 NC_009480.1 putative chromosome partitioning protein (YP_063238.1| chromosome partitioning protein [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825486.1| putative partitioning or sporulation protein [Streptomyces avermitilis MA-4680]). pfam00991, ParA, ParA family ATPase. InterPro: ParA family ATPase.; High confidence in function and specificity; putative chromosome partitioning protein 3293761 parA 5175456 parA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative chromosome partitioning protein YP_001223717.1 3292880 R 443906 CDS YP_001223718.1 148274157 5175446 complement(3293912..3294547) 1 NC_009480.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 3294547 gidB 5175446 gidB Clavibacter michiganensis subsp. michiganensis NCPPB 382 16S rRNA methyltransferase GidB YP_001223718.1 3293912 R 443906 CDS YP_001223719.1 148274158 5173460 complement(3295096..3295653) 1 NC_009480.1 putative DNA/RNA binding protein (YP_063240.1| hypothetical protein Lxx25260 [Leifsonia xyli subsp. xyli str. CTCB07]; AAK48405.1| R3H domain-containing protein [Mycobacterium tuberculosis CDC1551]). pfam01424, R3H, R3H domain. The function of the domain is predicted to be binding ssDNA. InterPro: R3H domain.; Function unclear; putative DNA/RNA binding protein 3295653 5173460 CMM_2974 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative DNA/RNA binding protein YP_001223719.1 3295096 R 443906 CDS YP_001223720.1 148274159 5174770 complement(3295650..3296612) 1 NC_009480.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3296612 5174770 CMM_2975 Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative inner membrane protein translocase component YidC YP_001223720.1 3295650 R 443906 CDS YP_001223721.1 148274160 5173584 complement(3296623..3296934) 1 NC_009480.1 conserved hypothetical protein (YP_063242.1| alpha-hemolysin [Leifsonia xyli subsp. xyli str. CTCB07]; NP_825490.1| hypothetical protein SAV4313 [Streptomyces avermitilis MA-4680]). pfam01809, DUF37, Domain of unknown function DUF37. This domain is found in short (70 amino acid) hypothetical proteins from various bacteria.; hypothetical protein 3296934 5173584 CMM_2976 Clavibacter michiganensis subsp. michiganensis NCPPB 382 hypothetical protein YP_001223721.1 3296623 R 443906 CDS YP_001223722.1 148274161 5174634 complement(3296931..3297272) 1 NC_009480.1 putative RNAse P, protein component (Q50789|RNPA_MYCTU Ribonuclease P protein component (RNaseP protein) (RNase P protein)(Protein C5); NP_602290.1| RNase P protein component [Corynebacterium glutamicum ATCC 13032]). pfam00825, Ribonuclease_P,Ribonuclease P.; High confidence in function and specificity; putative RNAse P, protein component 3297272 rnpA 5174634 rnpA Clavibacter michiganensis subsp. michiganensis NCPPB 382 putative RNAse P, protein component YP_001223722.1 3296931 R 443906 CDS YP_001223723.1 148274162 5173031 complement(3297276..3297413) 1 NC_009480.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3297413 rpmH 5173031 rpmH Clavibacter michiganensis subsp. michiganensis NCPPB 382 50S ribosomal protein L34 YP_001223723.1 3297276 R 443906 CDS