-- dump date 20120504_142641 -- class Genbank::CDS -- table cds_note -- id note YP_004371947.1 InterPro IPR003594; KEGG: apv:Apar_0001 ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004371948.1 COGs: COG0593 ATPase involved in DNA replication initiation; InterPro IPR003593:IPR013159:IPR013317:IPR020591; KEGG: apv:Apar_0002 chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: Chromosomal replication initiator DnaA domain; AAA ATPase; SPTR: Chromosomal replication initiator protein dnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004371949.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: apv:Apar_0003 DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004371950.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); InterPro IPR018078:IPR003395:IPR001238; KEGG: apv:Apar_0004 DNA replication and repair protein RecF; PFAM: SMC domain protein; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_004371951.1 KEGG: shi:Shel_00040 protein of unknown function (DUF721); SPTR: uncharacterized protein YP_004371952.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR018522:IPR003594:IPR001241:IPR013506:IPR 006171:IPR002288:IPR011557:IPR000565; KEGG: apv:Apar_0006 DNA gyrase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004371953.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR006691:IPR005743; KEGG: apv:Apar_0007 DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: uncharacterized protein; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase C-terminal domain, beta-propeller; DNA gyrase/topoisomerase IV, subunit A; TIGRFAM: DNA gyrase, A subunit YP_004371954.1 COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: ele:Elen_0010 protein of unknown function DUF151; PFAM: protein of unknown function DUF151; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259 YP_004371955.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR006402:IPR005833; KEGG: aat:D11S_1565 possible phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004371956.1 COGs: COG4495 conserved hypothetical protein; KEGG: btk:BT9727_0806 hypothetical protein; SPTR: uncharacterized protein YP_004371957.1 KEGG: psl:Psta_1198 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; SPTR: MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor YP_004371958.1 KEGG: mav:MAV_2064 virulence factor mce family protein; SPTR: uncharacterized protein YP_004371959.1 KEGG: nfa:nfa8210 hypothetical protein; SPTR: uncharacterized protein YP_004371960.1 KEGG: lma:LmjF34.2560 hypothetical protein; SPTR: uncharacterized protein YP_004371961.1 KEGG: gym:GYMC10_3953 hypothetical protein; SPTR: uncharacterized protein YP_004371962.1 KEGG: swi:Swit_1691 aldehyde dehydrogenase; SPTR: uncharacterized protein YP_004371963.1 KEGG: ank:AnaeK_3854 tetratricopeptide TPR_2 repeat protein; SPTR: Tetratricopeptide TPR_2 repeat protein YP_004371964.1 KEGG: ade:Adeh_3797 hypothetical protein; SPTR: uncharacterized protein YP_004371965.1 KEGG: pan:PODANSg1134 hypothetical protein; SPTR: uncharacterized protein YP_004371966.1 KEGG: bcn:Bcen_1336 malto-oligosyltrehalose synthase; SPTR: uncharacterized protein YP_004371967.1 KEGG: afw:Anae109_0115 peptidase M14 carboxypeptidase A; SPTR: Peptidase M14 carboxypeptidase A YP_004371968.1 KEGG: acp:A2cp1_3940 TPR repeat-containing protein; SPTR: TPR repeat-containing protein YP_004371969.1 KEGG: mno:Mnod_7655 chromosome segregation protein SMC; SPTR: Predicted protein YP_004371970.1 KEGG: cqu:CpipJ_CPIJ008387 aminopeptidase N; SPTR: Aminopeptidase N YP_004371971.1 KEGG: shi:Shel_25630 hypothetical protein; SPTR: uncharacterized protein YP_004371972.1 KEGG: bmr:BMI_I2040 cadmium-translocating P-type ATPase; SPTR: membrane protein YP_004371973.1 KEGG: gym:GYMC10_1852 hypothetical protein; SPTR: Hypothetical Cytosolic Protein YP_004371975.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: dhd:Dhaf_2599 protein of unknown function UPF0066; PFAM: Uncharacterised protein family UPF0066; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: methyltransferase, YaeB/AF_0241 family YP_004371976.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR010499; KEGG: dhd:Dhaf_2598 transcriptional regulator, MerR family; PFAM: MerR family transcripitonal regulator; transcription activator effector binding; SMART: MerR family transcripitonal regulator; SPTR: Transcriptional regulator; PFAM: MerR family regulatory protein; Bacterial transcription activator, effector binding domain YP_004371977.1 KEGG: gga:424885 Zic family member 4; SPTR: uncharacterized protein Z629R YP_004371978.1 KEGG: tpr:Tpau_3177 NADH-ubiquinone/plastoquinone oxidoreductase chain 6; SPTR: ABC transporter related protein YP_004371979.1 COGs: COG0015 Adenylosuccinate lyase; InterProIPR020557:IPR000362:IPR019468:IPR004769:IPR 003031; KEGG: apv:Apar_1351 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: uncharacterized protein; TIGRFAM: adenylosuccinate lyase; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase YP_004371980.1 KEGG: apv:Apar_1350 hypothetical protein; SPTR: uncharacterized protein YP_004371981.1 KEGG: ele:Elen_1602 hypothetical protein; SPTR: uncharacterized protein YP_004371982.1 KEGG: ele:Elen_1602 hypothetical protein; SPTR: uncharacterized protein YP_004371983.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: apv:Apar_1349 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004371984.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: apv:Apar_1348 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004371985.1 COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR018236:IPR001636; KEGG: apv:Apar_1347 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004371986.1 KEGG: apv:Apar_1346 hypothetical protein; SPTR: uncharacterized protein YP_004371987.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: apv:Apar_1352 peptidase M29 aminopeptidase II; PFAM: peptidase M29 aminopeptidase II; SPTR: uncharacterized protein; PFAM: Thermophilic metalloprotease (M29) YP_004371988.1 COGs: COG1109 Phosphomannomutase; InterPro IPR016066:IPR005844:IPR005845:IPR005841; KEGG: shi:Shel_23220 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: uncharacterized protein; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004371989.1 KEGG: apv:Apar_0103 hypothetical protein; SPTR: uncharacterized protein YP_004371990.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: apv:Apar_0104 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: uncharacterized protein; PFAM: Hsp20/alpha crystallin family YP_004371991.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: apv:Apar_0105 beta-lactamase domain protein; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004371992.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012795:IPR012796; KEGG: apv:Apar_0106 tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; SPTR: uncharacterized protein; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: TilS substrate C-terminal domain; PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004371993.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: apv:Apar_1317 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component YP_004371994.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: apv:Apar_1316 PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component; SPTR: PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component YP_004371995.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: cac:CA_C1459 PTS system, fructose(mannose)-specific IIC; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: PTS system, fructose; PFAM: PTS system sorbose-specific iic component YP_004371996.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: str:Sterm_3426 PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004371997.1 KEGG: apv:Apar_1313 hypothetical protein; SPTR: uncharacterized protein YP_004371998.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: dsy:DSY3813 hypothetical protein; PFAM: MarR family transcripitonal regulator; SMART: MarR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: MarR family YP_004371999.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: apv:Apar_0107 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: uncharacterized protein; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004372000.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003960:IPR003593:IPR003959:IPR000642:IPR 005936; KEGG: ccu:Ccur_02180 membrane protease FtsH catalytic subunit; PFAM: peptidase M41; AAA ATPase central domain protein; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004372001.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013; KEGG: apv:Apar_0109 PHP domain protein; PFAM: PHP domain protein; SPTR: uncharacterized protein; PFAM: PHP domain YP_004372002.1 InterPro IPR002921; KEGG: ele:Elen_2662 lipase class 3; PFAM: lipase class 3; SPTR: uncharacterized protein; PFAM: Lipase (class 3) YP_004372003.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280:IPR000241:IPR001566; KEGG: apv:Apar_0053 RNA methyltransferase, TrmA family; PFAM: RNA methylase; SPTR: uncharacterized protein; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004372004.1 InterPro IPR019931; KEGG: sgo:SGO_0107 LPXTG cell wall surface protein; SPTR: uncharacterized protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; TIGRFAM: streptococcal pilin isopeptide linkage domain YP_004372005.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 005225; KEGG: apv:Apar_0059 small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004372006.1 KEGG: pnu:Pnuc_0529 manganese transport protein; SPTR: manganese transport protein YP_004372007.1 InterPro IPR001387; KEGG: ele:Elen_0150 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Predicted transcriptional regulators; PFAM: Helix-turn-helix YP_004372008.1 KEGG: lxx:Lxx00900 BigG family transcription antiterminator; SPTR: uncharacterized protein YP_004372009.1 KEGG: gob:Gobs_2550 helicase domain protein; SPTR: Helicase domain protein YP_004372010.1 COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: mta:Moth_0711 peptidase U61, LD-carboxypeptidase A; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: Peptidase U61, LD-carboxypeptidase A; PFAM: LD-carboxypeptidase YP_004372011.1 KEGG: ddi:DDB_G0274301 Ras GTPase domain-containing protein; SPTR: Ras GTPase domain-containing protein YP_004372012.1 KEGG: sro:Sros_4591 transcriptional regulator, AsnC family; SPTR: Tetratricopeptide repeat domain protein YP_004372013.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; KEGG: cpy:Cphy_1404 flavoredoxin; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain YP_004372014.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078; KEGG: lmf:LMOf2365_1258 phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase; SPTR: uncharacterized protein; PFAM: Phosphoglycerate mutase family YP_004372015.1 COGs: COG2388 acetyltransferase; KEGG: lcz:LCAZH_2300 acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004372016.1 COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR003265; KEGG: ccu:Ccur_10470 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: uncharacterized protein; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004372017.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR001497:IPR014048; KEGG: pdi:BDI_0256 methylated DNA-protein cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: Methylated-DNA--[protein]-cysteine S-methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004372018.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR017871:IPR003439; KEGG: ele:Elen_1467 ABC transporter related; PFAM: ABC transporter related; SPTR: ABC transporter related; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004372019.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: sab:SAB2397c NADH-dependent flavin reductase; PFAM: nitroreductase; SPTR: Oxygen-insensitive NAD(P)H nitroreductase / Dihydropteridine reductase; PFAM: Nitroreductase family YP_004372020.1 KEGG: ele:Elen_1315 protein of unknown function DUF1200; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1200) YP_004372021.1 COGs: COG1363 Cellulase M and related protein; InterPro IPR008007; KEGG: efa:EF2724 M42 family peptidase; PFAM: peptidase M42 family protein; SPTR: uncharacterized protein; PFAM: M42 glutamyl aminopeptidase YP_004372022.1 COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR017969; KEGG: pca:Pcar_2431 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: TIGR00268 family protein YP_004372023.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: kra:Krad_0114 periplasmic binding protein/LacI transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372024.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR000583:IPR001347:IPR005855:IPR017932; KEGG: ele:Elen_2210 glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: sugar isomerase (SIS); glutamine amidotransferase class-II; SPTR: uncharacterized protein; TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004372025.1 KEGG: shi:Shel_23460 hypothetical protein; SPTR: uncharacterized protein YP_004372026.1 COGs: COG2249 NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: tde:TDE0354 general stress protein 14; PFAM: NAD(P)H dehydrogenase (quinone); SPTR: General stress protein 14; PFAM: Flavodoxin-like fold YP_004372027.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR018357:IPR001451:IPR005881; KEGG: lsp:Bsph_4643 serine acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase YP_004372028.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: apv:Apar_1312 SNARE associated Golgi protein; PFAM: SNARE associated Golgi protein; SPTR: uncharacterized protein; PFAM: SNARE associated Golgi protein YP_004372029.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544:IPR005786; KEGG: ccu:Ccur_08670 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: uncharacterized protein; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_004372030.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: ele:Elen_0090 LemA family protein; PFAM: LemA family protein; SPTR: uncharacterized protein; PFAM: LemA family YP_004372031.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR016192:IPR002125; KEGG: apv:Apar_0071 CMP/dCMP deaminase zinc-binding; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004372032.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: apv:Apar_0737 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372033.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: apv:Apar_0738 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter transmembrane region YP_004372034.1 KEGG: ppp:PHYPADRAFT_182167 hypothetical protein; SPTR: uncharacterized protein YP_004372035.1 KEGG: ele:Elen_2502 hypothetical protein; SPTR: uncharacterized protein YP_004372036.1 COGs: COG3158 K+ transporter; InterPro IPR003855; KEGG: apv:Apar_1015 K potassium transporter; PFAM: K potassium transporter; SPTR: uncharacterized protein; PFAM: K+ potassium transporter YP_004372037.1 COGs: COG1092 SAM-dependent methyltransferase; InterPro IPR004114:IPR000241:IPR017244; KEGG: apv:Apar_1014 THUMP domain protein; PFAM: THUMP domain-containing protein; RNA methylase; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: uncharacterized protein; PFAM: S-adenosylmethionine-dependent methyltransferase; THUMP domain YP_004372038.1 KEGG: psl:Psta_2516 hypothetical protein; SPTR: uncharacterized protein YP_004372039.1 InterPro IPR001387:IPR013096; KEGG: cbl:CLK_0680 transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Cupin domain; Helix-turn-helix YP_004372040.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR011701:IPR000109:IPR005279; KEGG: gka:GK2020 di-tripeptide ABC transporter (permease); PFAM: major facilitator superfamily MFS_1; TGF-beta receptor type I/II extracellular region; SPTR: uncharacterized protein; TIGRFAM: amino acid/peptide transporter; PFAM: POT family; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial YP_004372041.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR011701:IPR005279; KEGG: efa:EF0440 di-/tripeptide transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; TIGRFAM: amino acid/peptide transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial YP_004372042.1 COGs: COG2317 Zn-dependent carboxypeptidase; InterPro IPR001333; KEGG: hsl:OE4673F carboxypeptidase; PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; PRIAM: Carboxypeptidase Taq; SPTR: uncharacterized protein; PFAM: Carboxypeptidase Taq (M32) metallopeptidase YP_004372043.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR011701:IPR005279; KEGG: bld:BLi00449 YclF; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; TIGRFAM: amino acid/peptide transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial YP_004372044.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR000629:IPR006101:IPR006104:IPR006102:IPR 006103:IPR004199; KEGG: blt:Balat_0268 beta-galactosidase; PFAM: glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 42 domain 5 loop region; SPTR: Beta-galactosidase; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004372045.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: efa:EF3286 phosphosugar-binding transcriptional regulator, PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: phosphosugar-binding transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004372046.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR003352:IPR004501; KEGG: efa:EF3285 PTS system, IIC component; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, cellobiose-specific IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: phosphotransferase system, cellobiose specific, IIC component; PTS system, lactose/cellobiose family IIC component YP_004372047.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR003501:IPR013012; KEGG: lin:lin2472 hypothetical protein; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system, cellobiose-specific, IIB component; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004372048.1 COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: efa:EF3284 cystathionine gamma-synthase, PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine gamma-synthase; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004372050.1 KEGG: tde:TDE2258 surface antigen BspA, SPTR: uncharacterized protein YP_004372051.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR001411; KEGG: cbe:Cbei_5058 EmrB/QacA family drug resistance transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004372052.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: lrl:LC705_00390 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004372053.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: vvy:VVA1331 phosphotransferase system mannitol/fructose-specific IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: uncharacterized protein; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372054.1 COGs: COG3414 Phosphotransferase system galactitol-specific IIB component; InterPro IPR003501:IPR013011; KEGG: tit:Thit_0262 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004372055.1 COGs: COG3037 conserved hypothetical protein; KEGG: tit:Thit_0263 sugar-specific permease SgaT/UlaA; SPTR: Uncharacterized protein conserved in bacteria; PFAM: PTS system sugar-specific permease component; TC 4.A.7 YP_004372056.1 InterPro IPR019734; KEGG: tit:Thit_0264 hypothetical protein; SPTR: Tetratricopeptide repeat YP_004372057.1 KEGG: smc:SmuNN2025_1457 hypothetical protein; SPTR: uncharacterized protein; PFAM: Zeta toxin YP_004372058.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: kpn:KPN_00350 kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004372059.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: mrb:Mrub_1664 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372060.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: cth:Cthe_3148 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372061.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: cth:Cthe_3147 ABC transporter related protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372062.1 InterPro IPR000835; KEGG: apv:Apar_0883 transcriptional regulator, MarR family; PFAM: MarR family transcripitonal regulator; SMART: MarR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: MarR family YP_004372063.1 COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086; KEGG: ttu:TERTU_3249 isopentenyl-diphosphate delta-isomerase; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1 YP_004372064.1 COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: enc:ECL_01944 3,4-dihydroxybenzoate decarboxylase; PFAM: Carboxylyase-related protein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases YP_004372065.1 COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: sga:GALLO_1615 hypothetical protein; PFAM: protein of unknown function DUF554; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF554) YP_004372066.1 COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR003382:IPR004507; KEGG: bxe:Bxe_B2351 aromatic acid decarboxylase; PFAM: flavoprotein; SPTR: Polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases YP_004372067.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: ctc:CTC01842 regulator of efflux transporter; PFAM: MerR family transcripitonal regulator; SMART: MerR family transcripitonal regulator; SPTR: Transcriptional regulator, MerR family; PFAM: MerR, DNA binding; MerR family regulatory protein YP_004372068.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: apv:Apar_0645 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: uncharacterized protein; PFAM: Aldose 1-epimerase YP_004372069.1 COGs: COG0216 Protein chain release factor A; InterPro IPR005139:IPR000352:IPR004373; KEGG: apv:Apar_1310 peptide chain release factor 1; PFAM: Class I peptide chain release factor; PCRF domain protein; SPTR: Peptide chain release factor 1; TIGRFAM: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004372070.1 COGs: COG1835 acyltransferase; InterPro IPR020904:IPR002656; KEGG: ele:Elen_2521 acyltransferase 3; PFAM: acyltransferase 3; SPTR: uncharacterized protein; PFAM: Acyltransferase family YP_004372071.1 KEGG: ele:Elen_1602 hypothetical protein; SPTR: uncharacterized protein YP_004372072.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836:IPR004467; KEGG: ele:Elen_0287 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: uncharacterized protein; TIGRFAM: orotate phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase YP_004372073.1 COGs: COG0474 Cation transport ATPase; InterProIPR018303:IPR004014:IPR008250:IPR005834:IPR 006415:IPR001757; KEGG: cpy:Cphy_0543 magnesium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase YP_004372074.1 COGs: COG0546 phosphatase; InterPro IPR005834:IPR006402:IPR006439; KEGG: dvu:DVU0130 phosphoglycolate phosphatase, PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004372075.1 COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR017937:IPR013766:IPR005746:IPR017936:IPR 006662; KEGG: tro:trd_0071 thioredoxin; PFAM: Thioredoxin domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004372076.1 KEGG: apv:Apar_1319 hypothetical protein; SPTR: uncharacterized protein YP_004372077.1 InterPro IPR017900:IPR017896:IPR001080; KEGG: ele:Elen_3073 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; PFAM: 4Fe-4S binding domain YP_004372078.1 COGs: COG0443 Molecular chaperone; InterPro IPR018181:IPR013126:IPR012725:IPR001023; KEGG: apv:Apar_0094 chaperone protein DnaK; PFAM: Heat shock protein 70; PRIAM: Adenosinetriphosphatase; SPTR: Chaperone protein dnaK; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004372079.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: apv:Apar_0095 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE YP_004372080.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR018253:IPR001623:IPR002939:IPR003095; KEGG: apv:Apar_0096 chaperone DnaJ domain protein; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ C terminal region; DnaJ domain YP_004372081.1 COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: apv:Apar_0097 transcriptional regulator, MerR family; PFAM: MerR family transcripitonal regulator; SMART: MerR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: MerR family regulatory protein YP_004372082.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR018368:IPR003593:IPR004176:IPR003959:IPR 013093:IPR019489:IPR017730:IPR001270; KEGG: apv:Apar_0100 ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004372083.1 KEGG: cpy:Cphy_3720 phosphatase; SPTR: uncharacterized protein YP_004372084.1 KEGG: apv:Apar_0101 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004372085.1 KEGG: ele:Elen_1874 hypothetical protein; SPTR: uncharacterized protein YP_004372086.1 COGs: COG3824 conserved hypothetical protein; InterPro IPR010428; KEGG: ele:Elen_1532 protein of unknown function DUF1025; PFAM: protein of unknown function DUF1025; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1025) YP_004372087.1 KEGG: ele:Elen_1391 membrane protein; SPTR: Membrane protein YP_004372088.1 InterPro IPR001647; KEGG: ele:Elen_1392 TetR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family YP_004372089.1 COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495:IPR004392:IPR012202; KEGG: cbi:CLJ_B0500 hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: uncharacterized protein; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB YP_004372090.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR017900:IPR013027:IPR017896:IPR000759; KEGG: eel:EUBELI_01295 glutamate synthase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004372091.1 COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); InterPro IPR000688; KEGG: eel:EUBELI_01294 hydrogenase nickel incorporation protein HypA; PFAM: hydrogenase expression/synthesis HypA; SPTR: uncharacterized protein; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA YP_004372092.1 KEGG: phu:Phum_PHUM431970 hypothetical protein; SPTR: uncharacterized protein YP_004372093.1 InterPro IPR008454:IPR019931:IPR001899; KEGG: ccu:Ccur_00810 Cna protein B-type domain-containing protein; PFAM: Cna B domain protein; SPTR: Cna protein B-type domain-containing protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Cna protein B-type domain YP_004372094.1 COGs: COG3764 Sortase (surface protein transpeptidase); InterPro IPR005754; KEGG: ccu:Ccur_00840 sortase family protein, LPXTG-site transpeptidase; PFAM: peptidase C60 sortase A and B; SPTR: Sortase family protein, LPXTG-site transpeptidase; TIGRFAM: sortase family protein; manually curated; PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_004372095.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914:IPR006311; KEGG: ele:Elen_1224 extracellular solute-binding protein family 5; PFAM: extracellular solute-binding protein family 5; SPTR: ABC-type dipeptide transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004372096.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ele:Elen_1223 nickel-transporting ATPase; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Nickel-transporting ATPase; PFAM: Binding-protein-dependent transport system inner membrane component YP_004372097.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ele:Elen_1222 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004372098.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR017871:IPR002114:IPR003593:IPR003439:IPR 013563:IPR010066; KEGG: ele:Elen_1221 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004372099.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR017871:IPR003593:IPR003439:IPR013563:IPR 010066; KEGG: ele:Elen_1220 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: ABC-type oligopeptide transport system, ATPase component; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004372100.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: sga:GALLO_1852 hypothetical transcription regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Sugar isomerase; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004372101.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: sga:GALLO_1851 glycoside hydrolase, family 1; PFAM: glycoside hydrolase family 1; SPTR: Glycoside hydrolase, family 1; PFAM: Glycosyl hydrolase family 1 YP_004372102.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR018113:IPR003352:IPR001996:IPR013013; KEGG: sga:GALLO_1850 PTS system, sucrose specific, IIABC components; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, sucrose specific, IIABC components; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB YP_004372103.1 COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR006426:IPR017932; KEGG: lsp:Bsph_4225 asparagine synthetase [glutamine-hydrolyzing] 1; PFAM: asparagine synthase; glutamine amidotransferase class-II; SPTR: uncharacterized protein; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_004372104.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR018109:IPR013221:IPR004101:IPR005761; KEGG: shi:Shel_00220 UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase YP_004372105.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ccu:Ccur_10690 response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein; PFAM: response regulator receiver; LuxR family transcripitonal regulator; SMART: response regulator receiver; LuxR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004372106.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: ele:Elen_0564 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004372107.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ele:Elen_0563 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372108.1 KEGG: ele:Elen_0562 hypothetical protein; SPTR: uncharacterized protein YP_004372109.1 InterPro IPR013525; KEGG: ele:Elen_0561 hypothetical protein; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; PFAM: ABC-2 type transporter YP_004372110.1 InterPro IPR000182; KEGG: cdf:CD3159 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GNAT family acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004372111.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR017896; KEGG: cbe:Cbei_4835 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: uncharacterized protein YP_004372112.1 COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254:IPR005744; KEGG: ele:Elen_0246 channel protein, hemolysin III family; PFAM: Hly-III family protein; SPTR: uncharacterized protein; TIGRFAM: channel protein, hemolysin III family; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family YP_004372113.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: ele:Elen_0247 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; SPTR: uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004372114.1 KEGG: apv:Apar_0065 hypothetical protein; SPTR: uncharacterized protein YP_004372115.1 KEGG: apv:Apar_0066 hypothetical protein; SPTR: uncharacterized protein YP_004372116.1 KEGG: apv:Apar_0067 hypothetical protein; SPTR: uncharacterized protein YP_004372117.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: ccu:Ccur_10670 predicted xylanase/chitin deacetylase; PFAM: polysaccharide deacetylase; SPTR: uncharacterized protein; PFAM: Polysaccharide deacetylase YP_004372118.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: bde:BDP_0088 polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: uncharacterized protein; PFAM: Polysaccharide deacetylase YP_004372119.1 COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR000644:IPR006668; KEGG: apv:Apar_0069 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: uncharacterized protein; PFAM: MgtE intracellular N domain; CBS domain; TIGRFAM: Mg2+ transporter (mgtE) YP_004372120.1 COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR002052:IPR007848:IPR004556:IPR019874; KEGG: ele:Elen_1890 modification methylase, HemK family; PFAM: methyltransferase small; SPTR: uncharacterized protein; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; PFAM: Methyltransferase small domain; TIGRFAM: HemK family methylases YP_004372121.1 COGs: COG0009 translation factor (SUA5); InterPro IPR006070; KEGG: apv:Apar_1308 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: uncharacterized protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004372122.1 COGs: COG0554 Glycerol kinase; InterPro IPR018483:IPR018484:IPR018485:IPR005999; KEGG: trq:TRQ2_1322 glycerol kinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004372123.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: shi:Shel_21560 ribose-5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: uncharacterized protein; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004372124.1 COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR000836:IPR005765; KEGG: apv:Apar_1306 uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: uncharacterized protein; TIGRFAM: uracil phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004372125.1 KEGG: mrd:Mrad2831_3808 OPT family oligopeptide transporter; SPTR: uncharacterized protein YP_004372126.1 COGs: COG0356 F0F1-type ATP synthase subunit a; InterPro IPR000568; KEGG: apv:Apar_1304 ATP synthase F0, A subunit; PFAM: H+transporting two-sector ATPase A subunit; SPTR: ATP synthase subunit a; TIGRFAM: ATP synthase F0, A subunit; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004372127.1 InterPro IPR020537:IPR002379:IPR000454; KEGG: apv:Apar_1303 H+transporting two-sector ATPase C subunit; PFAM: H+transporting two-sector ATPase C subunit; SPTR: uncharacterized protein; PFAM: ATP synthase subunit C YP_004372128.1 COGs: COG0711 F0F1-type ATP synthase subunit b; InterPro IPR002146:IPR005864; KEGG: apv:Apar_1302 ATP synthase F0, B subunit; PFAM: H+transporting two-sector ATPase B/B' subunit; SPTR: ATP synthase subunit b; TIGRFAM: ATP synthase F0, B subunit; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004372129.1 COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); InterPro IPR000711; KEGG: apv:Apar_1301 H+transporting two-sector ATPase delta (OSCP) subunit; PFAM: H+transporting two-sector ATPase delta (OSCP) subunit; SPTR: uncharacterized protein; PFAM: ATP synthase delta (OSCP) subunit YP_004372130.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; InterProIPR020003:IPR004100:IPR000194:IPR000793:IPR 005294; KEGG: apv:Apar_1300 ATP synthase F1, alpha subunit; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SPTR: ATP synthase subunit alpha; TIGRFAM: ATP synthase F1, alpha subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit YP_004372131.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; InterPro IPR000131; KEGG: ele:Elen_1044 ATP synthase F1, gamma subunit; PFAM: H+transporting two-sector ATPase gamma subunit; SPTR: ATP synthase gamma chain; TIGRFAM: ATP synthase F1, gamma subunit; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_004372132.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; InterProIPR020003:IPR003593:IPR004100:IPR000194:IPR 000793:IPR005722; KEGG: apv:Apar_1298 ATP synthase F1, beta subunit; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP synthase F1, beta subunit; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 beta subunit YP_004372133.1 COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); InterPro IPR020546:IPR001469; KEGG: ccu:Ccur_12040 ATP synthase, F1 epsilon subunit; PFAM: ATPase, F1 complex, delta/epsilon subunit-like; SPTR: uncharacterized protein; TIGRFAM: ATP synthase F1, epsilon subunit; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria) YP_004372134.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001986:IPR005750; KEGG: apv:Apar_1296 UDP-N-acetylglucosamine1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004372135.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR001261:IPR002933:IPR011650:IPR010161; KEGG: apv:Apar_0155 peptidase T; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Tripeptide aminopeptidase; SPTR: uncharacterized protein; TIGRFAM: peptidase T; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: peptidase T YP_004372136.1 COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: apv:Apar_1294 iron (metal) dependent repressor, DtxR family; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: uncharacterized protein; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_004372137.1 COGs: COG0646 Methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726; KEGG: sth:STH2500 5-methyltetrahydrofolate S-homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; SPTR: uncharacterized protein; PFAM: Homocysteine S-methyltransferase YP_004372138.1 COGs: COG1109 Phosphomannomutase; InterProIPR005844:IPR005845:IPR005846:IPR005843:IPR 005841; KEGG: ele:Elen_3078 phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: uncharacterized protein; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004372139.1 COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); InterPro IPR008278:IPR002582:IPR004568; KEGG: apv:Apar_1247 holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: uncharacterized protein; TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004372140.1 COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: apv:Apar_1246 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: uncharacterized protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related; yjeF N-terminal region YP_004372141.1 COGs: COG0787 Alanine racemase; InterPro IPR020622:IPR001608:IPR011079:IPR000821; KEGG: apv:Apar_1245 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004372142.1 COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273; KEGG: ele:Elen_2784 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: uncharacterized protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_004372143.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: apv:Apar_1243 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004372144.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; InterPro IPR000905:IPR000182:IPR017861; KEGG: apv:Apar_0181 metalloendopeptidase, glycoprotease family; PFAM: peptidase M22 glycoprotease; GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: metalloendopeptidase, glycoprotease family; manually curated; PFAM: Acetyltransferase (GNAT) family; Glycoprotease family; TIGRFAM: glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family; universal bacterial protein YeaZ YP_004372145.1 InterPro IPR002477; KEGG: apv:Apar_0344 peptidoglycan-binding domain 1 protein; PFAM: Peptidoglycan-binding domain 1 protein; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain YP_004372146.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ele:Elen_0577 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: uncharacterized protein; PFAM: Polyprenyl synthetase YP_004372147.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: apv:Apar_0346 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: uncharacterized protein; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_004372148.1 COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR006311; KEGG: apv:Apar_1075 hypothetical protein; SPTR: uncharacterized protein YP_004372149.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: tmt:Tmath_1901 cobalt transport protein; PFAM: cobalt transport protein; SPTR: uncharacterized protein; PFAM: Cobalt transport protein YP_004372150.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871:IPR003593:IPR003439; KEGG: apv:Apar_0353 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372151.1 COGs: COG3601 membrane protein; InterPro IPR001484; KEGG: bla:BLA_1217 membrane protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1393) YP_004372152.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR006094:IPR011601:IPR003170:IPR016166; KEGG: apv:Apar_0355 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004372153.1 KEGG: mjl:Mjls_3056 hypothetical protein; SPTR: uncharacterized protein YP_004372154.1 COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: shi:Shel_26880 NCAIR mutase-like protein; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: uncharacterized protein; PFAM: AIR carboxylase YP_004372155.1 COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: afn:Acfer_1004 protein of unknown function DUF111; PFAM: protein of unknown function DUF111; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein YP_004372156.1 InterPro IPR008454; KEGG: ccu:Ccur_00830 Cna protein B-type domain-containing protein; PFAM: Cna B domain protein; SPTR: uncharacterized protein; PFAM: Cna protein B-type domain YP_004372157.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: apv:Apar_0076 phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004372158.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: shi:Shel_00600 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: uncharacterized protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004372159.1 COGs: COG0148 Enolase; InterProIPR020809:IPR003006:IPR020811:IPR020810:IPR 000941; KEGG: ccu:Ccur_10480 enolase; PFAM: Enolase-like; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004372160.1 KEGG: bpt:Bpet1833 dihydrolipoamide succinyltransferase; SPTR: Ribonuclease, Rne/Rng family protein YP_004372161.1 KEGG: shi:Shel_01430 hypothetical protein; SPTR: uncharacterized protein YP_004372162.1 InterPro IPR001387; KEGG: ele:Elen_1959 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix YP_004372163.1 KEGG: ele:Elen_0809 hypothetical protein; SPTR: uncharacterized protein YP_004372164.1 KEGG: ccu:Ccur_03910 septum formation initiator; SPTR: uncharacterized protein; PFAM: Septum formation initiator YP_004372165.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: apv:Apar_0128 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: uncharacterized protein; PFAM: Ppx/GppA phosphatase family YP_004372166.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: cbl:CLK_0642 HTH-type transcriptional regulator YciT; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372167.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterProIPR017900:IPR001989:IPR007197:IPR012839:IPR 011352:IPR017896; KEGG: rcp:RCAP_rcc02199 [pyruvate formate-lyase]-activating enzyme; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: uncharacterized protein; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM superfamily; TIGRFAM: glycyl-radical enzyme activating protein family YP_004372168.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR019777:IPR004184:IPR001150:IPR010098; KEGG: cbe:Cbei_0705 pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Pyruvate formate-lyase; TIGRFAM: pyruvate formate-lyase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: pyruvate formate-lyase YP_004372169.1 COGs: COG0176 Transaldolase; InterPro IPR018225:IPR001585; KEGG: clj:CLJU_c25960 transaldolase; PFAM: Transaldolase; PRIAM: Transaldolase; SPTR: uncharacterized protein; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004372170.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704:IPR018405; KEGG: smc:SmuNN2025_0263 PTS system mannose-specific component IID; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: PTS family mannose/fructose/sorbose porter component IID; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID component; TC 4.A.6 YP_004372171.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: ssa:SSA_1919 phosphotransferase system, mannose-specific EIIC, PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: PTS family mannose porter, IIC component; PFAM: PTS system sorbose-specific iic component YP_004372172.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004701:IPR004720; KEGG: lwe:lwe0082 PTS system, mannose-specific, IIAB component; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; PFAM: PTS system fructose IIA component; PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component; PTS system, mannose/fructose/sorbose family, IIB component YP_004372173.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR001387:IPR019759; KEGG: ccu:Ccur_03030 SOS response transcriptional repressor, RecA-mediated autopeptidase; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: prophage L54a, repressor protein; PFAM: Helix-turn-helix; Peptidase S24-like YP_004372174.1 KEGG: eel:EUBELI_00139 hypothetical protein; SPTR: uncharacterized protein YP_004372175.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cpy:Cphy_2887 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2 YP_004372176.1 KEGG: eel:EUBELI_00627 hypothetical protein; SPTR: uncharacterized protein YP_004372177.1 COGs: COG1259 conserved hypothetical protein; InterPro IPR003729; KEGG: apv:Apar_0008 protein of unknown function DUF151; PFAM: protein of unknown function DUF151; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259 YP_004372178.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: cpy:Cphy_2914 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: uncharacterized protein; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004372179.1 COGs: COG2213 Phosphotransferase system mannitol-specific IIBC component; InterPro IPR002178:IPR003352:IPR003501:IPR013014; KEGG: tau:Tola_0283 PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, mannitol-specific IIC component; TC 4.A.2.1.2 YP_004372180.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR002173:IPR011611:IPR017583:IPR002139; KEGG: apv:Apar_1252 1-phosphofructokinase; PFAM: PfkB domain protein; PRIAM: 1-phosphofructokinase; SPTR: 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family YP_004372181.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: csc:Csac_0869 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004372182.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: ate:Athe_0705 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372183.1 KEGG: shi:Shel_26280 hypothetical protein; SPTR: uncharacterized protein; manually curated YP_004372184.1 COGs: COG0172 Seryl-tRNA synthetase; InterProIPR015866:IPR002314:IPR002317:IPR006195:IPR 018156; KEGG: apv:Apar_1338 seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like; PRIAM: Serine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: seryl-tRNA synthetase; PFAM: tRNA synthetase class II core domain (G, H, P, S and T); Seryl-tRNA synthetase N-terminal domain; TIGRFAM: seryl-tRNA synthetase YP_004372185.1 KEGG: dwi:Dwil_GK22023 GK22023 gene product from transcript GK22023-RA; SPTR: Predicted protein YP_004372186.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701:IPR001958; KEGG: ele:Elen_1186 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004372187.1 KEGG: ele:Elen_2231 hypothetical protein; SPTR: uncharacterized protein; PFAM: TspO/MBR family YP_004372188.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: blt:Balat_0118 Tas protein; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family YP_004372189.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; InterPro IPR005474:IPR005475:IPR005476; KEGG: cac:CA_P0106 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: Transketolase central region; Transketolase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SPTR: uncharacterized protein; manually curated; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004372190.1 InterPro IPR003607:IPR006674:IPR006675; KEGG: mla:Mlab_0181 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain YP_004372191.1 COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: bad:BAD_0916 hypothetical protein; PFAM: protein of unknown function DUF1113; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1113) YP_004372192.1 SPTR: uncharacterized protein YP_004372193.1 KEGG: ele:Elen_0684 hypothetical protein; SPTR: uncharacterized protein YP_004372194.1 KEGG: tcr:504213.50 hypothetical protein; SPTR: uncharacterized protein YP_004372195.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR005467:IPR008358; KEGG: ele:Elen_0685 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004372196.1 COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: bad:BAD_0916 hypothetical protein; PFAM: protein of unknown function DUF1113; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1113) YP_004372197.1 KEGG: ele:Elen_2293 hypothetical protein; SPTR: uncharacterized protein YP_004372198.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ele:Elen_0683 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372199.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ele:Elen_0682 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004372200.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: ere:EUBREC_3362 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004372201.1 COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: ele:Elen_2734 TetR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004372202.1 InterPro IPR011701; KEGG: ele:Elen_2733 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Permeases of the major facilitator superfamily; PFAM: Major Facilitator Superfamily YP_004372203.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tit:Thit_0408 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372204.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: cfl:Cfla_3230 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter YP_004372205.1 COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: ele:Elen_2912 zinc/iron permease; PFAM: zinc/iron permease; SPTR: uncharacterized protein; PFAM: ZIP Zinc transporter YP_004372206.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: mga:MGA_0295 HAD superfamily hydrolase Cof; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004372207.1 KEGG: apv:Apar_0148 TetR family transcriptional regulator; SPTR: uncharacterized protein YP_004372208.1 COGs: COG3581 conserved hypothetical protein; InterPro IPR002731:IPR018709:IPR008275; KEGG: apv:Apar_0149 CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase BadF/BadG/BcrA/BcrD type; SPTR: uncharacterized protein; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase YP_004372209.1 COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: shi:Shel_15130 thioredoxin-like protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: uncharacterized protein; PFAM: NifU-like domain YP_004372210.1 COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180:IPR011962; KEGG: apv:Apar_0993 deoxycytidine triphosphate deaminase; PFAM: deoxyUTP pyrophosphatase; SPTR: Deoxycytidine triphosphate deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; PFAM: 2'-deoxycytidine 5'-triphosphate deaminase (DCD); TIGRFAM: deoxycytidine triphosphate deaminase YP_004372211.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: ccu:Ccur_12220 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: uncharacterized protein; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004372212.1 KEGG: lfe:LAF_1406 hypothetical protein; SPTR: uncharacterized protein YP_004372213.1 COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: shi:Shel_07020 conserved hypothetical protein TIGR01033; PFAM: protein of unknown function DUF28; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004372214.1 KEGG: ele:Elen_0275 hypothetical protein; SPTR: uncharacterized protein YP_004372215.1 InterPro IPR018730; KEGG: ele:Elen_0274 hypothetical protein; PFAM: Protein of unknown function DUF2273; SPTR: uncharacterized protein; PFAM: Small integral membrane protein (DUF2273) YP_004372216.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: apv:Apar_0389 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004372217.1 COGs: COG1135 ABC-type metal ion transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: ele:Elen_2019 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372218.1 COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR000515; KEGG: ccu:Ccur_08270 ABC-type metal ion transport system, permease component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004372219.1 COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872:IPR006311:IPR017909; KEGG: ccu:Ccur_08260 ABC-type metal ion transport system, periplasmic component/surface antigen; PFAM: NLPA lipoprotein; SPTR: uncharacterized protein; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family YP_004372220.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: clo:HMPREF0868_0784 hypothetical protein; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004372221.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR018369:IPR020818:IPR001476; KEGG: apv:Apar_0183 chaperonin Cpn10; PFAM: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: Chaperonin 10 Kd subunit YP_004372222.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR018370:IPR002423:IPR001844; KEGG: apv:Apar_0184 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004372223.1 InterPro IPR006058:IPR017900:IPR017896; KEGG: apv:Apar_0185 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein YP_004372224.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR002917:IPR013029:IPR004396:IPR006073; KEGG: apv:Apar_0186 GTP-binding protein YchF; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: uncharacterized protein; TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004372225.1 KEGG: ele:Elen_1294 protein of unknown function DUF1648; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1648) YP_004372226.1 COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR020827:IPR006034; KEGG: ele:Elen_0759 L-asparaginase, type I; PFAM: Asparaginase/glutaminase; SPTR: uncharacterized protein; PFAM: Asparaginase YP_004372227.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991:IPR001674:IPR004739:IPR017926:IPR 011702:IPR001317:IPR006220; KEGG: ccu:Ccur_10270 GMP synthase (glutamine-hydrolyzing); PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; SPTR: uncharacterized protein; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: Glutamine amidotransferase class-I; GMP synthase C terminal domain; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004372228.1 InterPro IPR006442; KEGG: ccu:Ccur_13030 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein YP_004372229.1 COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: lsa:LSA0159 hypothetical protein; PFAM: YheO-like domain-containing protein; SPTR: uncharacterized protein; PFAM: YheO-like PAS domain YP_004372230.1 COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR019897:IPR006175:IPR006056; KEGG: hmu:Hmuk_0939 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP YP_004372231.1 KEGG: mmu:67645 RIKEN cDNA 4930511I11 gene; SPTR: Toxin-antitoxin system, toxin component, Fic family YP_004372232.1 KEGG: coc:Coch_2162 hypothetical protein; SPTR: uncharacterized protein YP_004372233.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002293; KEGG: tde:TDE0445 amino acid permease; PFAM: amino acid permease-associated region; SPTR: Amino acid permease; PFAM: Amino acid permease; TC 2.A.3 YP_004372234.1 COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: cdf:CD1188 glutamine amidotransferase; PFAM: peptidase C26; SPTR: Class I glutamine amidotransferase; PFAM: Peptidase C26 YP_004372235.1 COGs: COG3681 conserved hypothetical protein; InterPro IPR021144; KEGG: bpo:BP951000_1867 hypothetical protein; SPTR: UPF0597 protein RUMGNA_00647; PFAM: Serine dehydratase alpha chain YP_004372236.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: cac:CA_C1558 ABC-type transport system,membrane ATPase component; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372237.1 KEGG: ele:Elen_2509 hypothetical protein; SPTR: uncharacterized protein YP_004372238.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR019825:IPR003593:IPR003439; KEGG: ele:Elen_2508 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372239.1 COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: ele:Elen_2507 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family YP_004372240.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006103; KEGG: bad:BAD_1534 glycosyl hydrolase; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 TIM barrel; SPTR: uncharacterized protein; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004372241.1 COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: shi:Shel_04880 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterised ACR, COG2135 YP_004372242.1 KEGG: syn:slr0121 hypothetical protein YP_004372243.1 COGs: COG1476 transcriptional regulator protein; InterPro IPR001387; KEGG: cby:CLM_0683 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Conserved domain protein; PFAM: Helix-turn-helix YP_004372244.1 KEGG: eat:EAT1b_1420 hypothetical protein; SPTR: uncharacterized protein YP_004372245.1 COGs: COG2135 conserved hypothetical protein; InterPro IPR003738; KEGG: shi:Shel_04880 hypothetical protein; PFAM: protein of unknown function DUF159; SPTR: Uncharacterized conserved protein; PFAM: Uncharacterised ACR, COG2135 YP_004372246.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: fnu:FN0672 ATPase; SPTR: uncharacterized protein YP_004372247.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: csc:Csac_0600 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: sugar phosphate isomerasesiderophore/epimerase; PFAM: Xylose isomerase-like TIM barrel YP_004372248.1 COGs: COG3507 Beta-xylosidase; InterPro IPR000421:IPR006710:IPR022272; KEGG: cmi:CMM_0103 beta-xylosidase glycosyl hydrolase family 43; PFAM: glycoside hydrolase family 43; coagulation factor 5/8 type domain protein; SPTR: beta-xylosidase, glycosyl hydrolase family 43; PFAM: F5/8 type C domain; Glycosyl hydrolases family 43 YP_004372249.1 InterPro IPR013737:IPR008902; KEGG: scb:SCAB_22771 rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: uncharacterized protein; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004372250.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: smf:Smon_1309 Na+/melibiose symporter and related transporter-like protein; PFAM: major facilitator superfamily MFS_1; SPTR: Na+/melibiose symporter and related transporters; PFAM: Major Facilitator Superfamily YP_004372251.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103:IPR006101; KEGG: pjd:Pjdr2_4080 beta-galactosidase; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; PRIAM: Beta-glucuronidase; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain YP_004372252.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360; KEGG: ach:Achl_0421 glycoside hydrolase family 1; PFAM: glycoside hydrolase family 1; SPTR: Beta-glucosidase; PFAM: Glycosyl hydrolase family 1 YP_004372253.1 InterPro IPR001647; KEGG: cac:CA_C0724 AcrR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: Prophage Sa05, transcriptional regulator, ; PFAM: Bacterial regulatory proteins, tetR family YP_004372254.1 COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: lbr:LVIS_0145 transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004372255.1 InterPro IPR001387; KEGG: azl:AZL_e02380 transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004372256.1 COGs: COG0469 Pyruvate kinase; InterPro IPR015793:IPR015794:IPR001697; KEGG: apv:Apar_1040 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004372257.1 COGs: COG3940 beta-xylosidase; InterPro IPR006710; KEGG: ske:Sked_03050 predicted beta-xylosidase; PFAM: glycoside hydrolase family 43; PRIAM: Alpha-N-arabinofuranosidase; SPTR: Predicted beta-xylosidase; PFAM: Glycosyl hydrolases family 43 YP_004372258.1 InterPro IPR020480:IPR000576; KEGG: bfa:Bfae_28670 galactoside permease; SPTR: Oligosaccharide:H+ symporter; TIGRFAM: oligosaccharide/H+ symporter, major facilitator superfamily (MFS); PFAM: LacY proton/sugar symporter; TIGRFAM: oligosaccharide:H+ symporter YP_004372259.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ske:Sked_03890 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372260.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR010524:IPR002197; KEGG: clj:CLJU_c03810 transcriptional regulator; PFAM: Propionate catabolism activator domain-containing protein; helix-turn-helix Fis-type; SPTR: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Propionate catabolism activator YP_004372261.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: clj:CLJU_c03820 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: Uncharacterized protein conserved in bacteria; PFAM: Protein of unknown function, DUF1537 YP_004372262.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: clj:CLJU_c03830 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Alcohol dehydrogenase, class IV; PFAM: Iron-containing alcohol dehydrogenase YP_004372263.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR005263; KEGG: clj:CLJU_c03840 dihydrodipicolinate synthese family protein; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_004372264.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: ere:EUBREC_1204 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase YP_004372265.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: msu:MS0068 SerA protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: SerA protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004372266.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: ebi:EbC_07630 MFS transporter, phthalate permease family; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; TIGRFAM: D-galactonate transporter YP_004372267.1 KEGG: cbi:CLJ_0080 hypothetical protein; SPTR: uncharacterized protein YP_004372268.1 KEGG: fps:FP0168 cell surface leucine-rich repeat-containing protein; SPTR: Probable cell surface protein (Leucine-rich repeat protein); PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); Cna protein B-type domain YP_004372269.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 018303:IPR001757:IPR000695; KEGG: apv:Apar_1038 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004372270.1 COGs: COG1162 GTPase; InterPro IPR010914:IPR004881; KEGG: apv:Apar_1037 GTPase EngC; PFAM: GTPase EngC; SPTR: uncharacterized protein; TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004372271.1 InterPro IPR013974:IPR017592; KEGG: ele:Elen_0535 Flp pilus assembly protein CpaB; PFAM: SAF domain protein; SPTR: uncharacterized protein; TIGRFAM: Flp pilus assembly protein CpaB; PFAM: SAF domain; TIGRFAM: Flp pilus assembly protein CpaB YP_004372272.1 COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: apv:Apar_1035 chromosome partitioning ATPase-like protein; SPTR: uncharacterized protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004372273.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482:IPR017975; KEGG: apv:Apar_1034 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: uncharacterized protein; PFAM: Type II/IV secretion system protein YP_004372274.1 COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: apv:Apar_1033 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004372275.1 InterPro IPR018076; KEGG: apv:Apar_1032 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: uncharacterized protein; PFAM: Bacterial type II secretion system protein F domain YP_004372276.1 KEGG: ccu:Ccur_13130 class III signal peptide-containing protein; SPTR: uncharacterized protein YP_004372277.1 KEGG: cre:CHLREDRAFT_187114 hypothetical protein; SPTR: uncharacterized protein YP_004372278.1 KEGG: ele:Elen_0541 hypothetical protein; SPTR: uncharacterized protein YP_004372279.1 KEGG: apv:Apar_1028 TadE family protein; SPTR: uncharacterized protein; PFAM: TadE-like protein YP_004372280.1 KEGG: apv:Apar_1027 hypothetical protein; SPTR: uncharacterized protein YP_004372281.1 KEGG: apv:Apar_1026 hypothetical protein; SPTR: uncharacterized protein YP_004372282.1 InterPro IPR003795; KEGG: bpt:Bpet2081 hypothetical protein; PFAM: protein of unknown function DUF192; SPTR: uncharacterized protein; manually curated; PFAM: Uncharacterized ACR, COG1430 YP_004372283.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: eat:EAT1b_0189 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372284.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR018113:IPR003352:IPR 018114:IPR011535; KEGG: ddc:Dd586_0344 PTS system, sucrose-specific IIBC subunit; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component YP_004372285.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148:IPR013189:IPR018053:IPR001362; KEGG: brm:Bmur_0254 sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 32 C terminal; Glycosyl hydrolases family 32 N-terminal domain YP_004372286.1 COGs: COG2730 Endoglucanase; InterPro IPR005829; KEGG: apv:Apar_1088 glucan 1,3-beta-glucosidase; SPTR: uncharacterized protein YP_004372287.1 COGs: COG0313 methyltransferase; InterPro IPR000878:IPR018063:IPR008189; KEGG: apv:Apar_1087 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: uncharacterized protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004372288.1 COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR015413:IPR013090:IPR014758:IPR002304; KEGG: apv:Apar_1085 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); SPTR: uncharacterized protein; TIGRFAM: methionyl-tRNA synthetase; PFAM: tRNA synthetases class I (M); TIGRFAM: methionyl-tRNA synthetase YP_004372289.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR001737:IPR011530:IPR020596:IPR020598; KEGG: apv:Apar_1084 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase-like; SPTR: uncharacterized protein; TIGRFAM: dimethyladenosine transferase; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004372290.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR001130; KEGG: apv:Apar_1083 TatD-related deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004372291.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: pmx:PERMA_0046 ATPase; SPTR: uncharacterized protein YP_004372292.1 InterPro IPR017909:IPR019546:IPR006311; KEGG: cmi:CMM_0879 sugar ABC transporter, substrate-binding protein; PFAM: Twin-arginine translocation pathway, signal sequence, subgroup; SPTR: uncharacterized protein YP_004372293.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: ote:Oter_3322 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372294.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003439:IPR017871:IPR018171:IPR003593; KEGG: cno:NT01CX_0164 ribose transport ATP-binding protein RbsA; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372295.1 COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: cwo:Cwoe_4325 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372296.1 COGs: COG2160 L-arabinose isomerase; InterPro IPR003762; KEGG: pjd:Pjdr2_2502 L-arabinose isomerase; PFAM: L-arabinose isomerase; PRIAM: L-arabinose isomerase; SPTR: L-arabinose isomerase; PFAM: L-arabinose isomerase; L-arabinose isomerase C-terminal domain YP_004372297.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: pru:PRU_0419 carbohydrate kinase domain-containing protein; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004372298.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: apv:Apar_0330 L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; SPTR: L-ribulose-5-phosphate 4-epimerase; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004372299.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183:IPR018052; KEGG: cpy:Cphy_0556 aldose 1-epimerase; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: uncharacterized protein; PFAM: Aldose 1-epimerase YP_004372300.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: apv:Apar_0150 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372301.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967:IPR018044; KEGG: shi:Shel_13430 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; SPTR: uncharacterized protein; PFAM: D-alanyl-D-alanine carboxypeptidase YP_004372302.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: clj:CLJU_c14380 regulatory protein VanR; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004372303.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR005467:IPR003661:IPR003594:IPR004358; KEGG: ckr:CKR_0015 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004372304.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003439:IPR017940:IPR001140:IPR017871:IPR 003593; KEGG: sth:STH2015 ABC transporter ATP-binding protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter transmembrane region YP_004372305.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003439:IPR017940:IPR001140:IPR017871:IPR 003593; KEGG: clj:CLJU_c26230 transport protein ATPase/permease; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372306.1 InterPro IPR000835; KEGG: sga:GALLO_1286 transcriptional regulator, MarR family; PFAM: MarR family transcripitonal regulator; SMART: MarR family transcripitonal regulator; SPTR: uncharacterized protein YP_004372307.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: ssp:SSP0306 acetyltransferase; SPTR: Galactoside O-acetyltransferase; PFAM: Maltose acetyltransferase; Bacterial transferase hexapeptide (three repeats) YP_004372308.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: afn:Acfer_1559 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family YP_004372309.1 KEGG: shi:Shel_03240 hypothetical protein; SPTR: uncharacterized protein; PFAM: Transposase YP_004372310.1 COGs: COG0426 flavoprotein; InterPro IPR008254:IPR016440; KEGG: apv:Apar_0063 beta-lactamase domain protein; PFAM: flavodoxin/nitric oxide synthase; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin YP_004372311.1 KEGG: kpu:KP1_0760 PTS permease; SPTR: uncharacterized protein YP_004372312.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: eel:EUBELI_00879 antibiotic transport system ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Antibiotic transport system ATP-binding protein; PFAM: ABC transporter YP_004372313.1 KEGG: ere:EUBREC_2860 hypothetical protein; SPTR: uncharacterized protein YP_004372314.1 KEGG: ere:EUBREC_3204 hypothetical protein; SPTR: uncharacterized protein YP_004372315.1 KEGG: eel:EUBELI_00878 hypothetical protein; SPTR: uncharacterized protein YP_004372316.1 InterPro IPR010916; KEGG: spw:SPCG_1257 pneumococcal surface protein A; SPTR: Pneumococcal surface protein A YP_004372317.1 KEGG: cqu:CpipJ_CPIJ011516 surfeit locus protein 4; SPTR: Surfeit locus protein 4 YP_004372318.1 InterPro IPR001647; KEGG: shi:Shel_04120 hypothetical protein; PFAM: TetR family transcripitonal regulator; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004372319.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: blt:Balat_0161 ATP binding protein of ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372320.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: gva:HMPREF0424_0133 efflux ABC transporter, permease protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372321.1 COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569:IPR002579:IPR018506; KEGG: pdi:BDI_2038 peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A; Methionine sulfoxide reductase B; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-S-sulfoxide reductase/methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase YP_004372322.1 COGs: COG1741 Pirin-related protein; InterPro IPR003829:IPR008778:IPR012093; KEGG: cce:Ccel_2756 pirin domain protein; PFAM: Pirin domain protein; SPTR: Pirin domain protein; PFAM: Pirin C-terminal cupin domain; Pirin YP_004372323.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140; KEGG: afn:Acfer_1520 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_004372324.1 KEGG: rpc:RPC_0363 DNA mismatch repair protein MutS; SPTR: uncharacterized protein YP_004372325.1 KEGG: mdo:100012135 similar to hippostasin prostate type; SPTR: uncharacterized protein YP_004372326.1 COGs: COG4990 conserved hypothetical protein; InterPro IPR000169; KEGG: lsp:Bsph_0275 hypothetical protein; SPTR: uncharacterized protein YP_004372327.1 InterPro IPR000792; KEGG: ele:Elen_0181 transcriptional regulator, LuxR family; PFAM: LuxR family transcripitonal regulator; SMART: LuxR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, luxR family YP_004372328.1 KEGG: nha:Nham_1684 hypothetical protein; SPTR: uncharacterized protein YP_004372329.1 KEGG: ere:EUBREC_3204 hypothetical protein; SPTR: uncharacterized protein YP_004372330.1 KEGG: ere:EUBREC_3203 hypothetical protein; SPTR: uncharacterized protein YP_004372331.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: eel:EUBELI_20089 antibiotic transport system ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372332.1 KEGG: apv:Apar_0362 hypothetical protein; SPTR: uncharacterized protein YP_004372333.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: ele:Elen_1535 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372334.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: ele:Elen_1536 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372335.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: ele:Elen_1535 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372336.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: apv:Apar_1068 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004372337.1 InterPro IPR003849; KEGG: sth:STH1250 hypothetical protein; PFAM: YajC family protein; SPTR: uncharacterized protein; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_004372338.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720:IPR018455; KEGG: sth:STH1249 PTS system N-acetylgalactosamine-specific IIB component; PFAM: PTS system sorbose subfamily IIB component; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB component YP_004372339.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: sth:STH1248 PTS system N-acetylgalactosamine-specific IIC component; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: PTS system N-acetylgalactosamine-specific IIC component; PFAM: PTS system sorbose-specific iic component YP_004372340.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: sth:STH1247 PTS system N-acetylgalactosamine-specific IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6.1.4 YP_004372341.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: apv:Apar_1063 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372342.1 COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: apv:Apar_1062 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain; TIGRFAM: sugar isomerase, AgaS family YP_004372343.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: apv:Apar_1061 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: uncharacterized protein; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004372344.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sga:GALLO_0184 aldose 1-epimerase; PFAM: Aldose 1-epimerase; SPTR: uncharacterized protein; PFAM: Aldose 1-epimerase YP_004372345.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR002173:IPR017583; KEGG: slg:SLGD_00827 tagatose-6-phosphate kinase/1-phosphofructokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: tagatose-6-phosphate kinase; hexose kinase, 1-phosphofructokinase family YP_004372346.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: bcl:ABC3573 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372347.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: str:Sterm_3717 PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372348.1 COGs: COG3414 Phosphotransferase system galactitol-specific IIB component; InterPro IPR013011:IPR003501; KEGG: bcl:ABC3571 PTS system, galactitol-specific enzyme II, B component; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: B component PTS system galactitol-specific enzyme II; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TC 4.A.5.1.1 YP_004372349.1 COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR013014:IPR004703; KEGG: lrh:LGG_00343 PTS system galactitol-specific transporter subunit IIC; PFAM: PTS system Galactitol-specific IIC component; SPTR: PTS system protein; PFAM: PTS system sugar-specific permease component; TIGRFAM: PTS system, galactitol-specific IIC component YP_004372350.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR002328; KEGG: bcl:ABC3569 galactitol-1-phosphate 5-dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004372351.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: mrb:Mrub_1701 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372352.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: apv:Apar_1070 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004372353.1 COGs: COG1203 helicase; InterPro IPR014001:IPR006474; KEGG: tfu:Tfu_1601 CRISPR-associated helicase Cas3 family protein protein; SMART: DEAD-like helicase; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD YP_004372354.1 InterPro IPR013381; KEGG: nfa:nfa44270 hypothetical protein; PFAM: CRISPR-associated protein Cse1; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse1 family; PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 YP_004372355.1 InterPro IPR013382; KEGG: gva:HMPREF0424_0761 CRISPR system CASCADE complex protein CasB; PFAM: CRISPR-associated protein Cse2; SPTR: CRISPR-associated protein, Cse2 family; TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 YP_004372356.1 InterPro IPR010148; KEGG: nml:Namu_3052 CRISPR-associated protein, CSE4 family; PFAM: CRISPR-associated protein CT1975; SPTR: CRISPR-associated protein, Cse4 family; TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI YP_004372357.1 InterPro IPR010147:IPR013422; KEGG: saq:Sare_2576 CRISPR-associated Cas5 family protein; SPTR: CRISPR-associated protein Cas5; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI; CRISPR-associated protein Cas5, N-terminal domain YP_004372358.1 InterPro IPR010179; KEGG: nml:Namu_3050 CRISPR-associated protein, CSE3 family; PFAM: CRISPR-associated protein CT1974; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI YP_004372359.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019851; KEGG: nml:Namu_3049 CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1; CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI YP_004372360.1 InterPro IPR010152; KEGG: nml:Namu_3048 CRISPR-associated protein Cas2; PFAM: CRISPR-associated protein Cas2; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas2; manually curated; PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI YP_004372361.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR013497:IPR013498:IPR016160:IPR 000380:IPR006154:IPR003601:IPR003602; KEGG: apv:Apar_1093 DNA topoisomerase type IA central domain protein; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; DNA topoisomerase type IA zn finger domain protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: uncharacterized protein; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, archaeal YP_004372362.1 COGs: COG0125 Thymidylate kinase; InterPro IPR000062:IPR018094; KEGG: apv:Apar_1092 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase YP_004372363.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: apv:Apar_1091 DNA-directed DNA polymerase; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, delta' subunit YP_004372364.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: apv:Apar_1090 PSP1 domain protein; PFAM: PSP1 domain protein; SPTR: uncharacterized protein; PFAM: PSP1 C-terminal conserved region YP_004372365.1 COGs: COG1040 amidophosphoribosyltransferase; KEGG: ele:Elen_1211 hypothetical protein; SPTR: uncharacterized protein; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004372366.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: apv:Apar_0984 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004372367.1 COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: apv:Apar_0983 sigma 54 modulation protein/ribosomal protein S30EA; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; SPTR: uncharacterized protein; TIGRFAM: ribosomal subunit interface protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004372368.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: apv:Apar_0982 DegV family protein; PFAM: DegV family protein; SPTR: uncharacterized protein; TIGRFAM: degV family protein; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004372369.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: apv:Apar_0981 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 3-hydroxyisobutyrate dehydrogenase; SPTR: uncharacterized protein; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase YP_004372370.1 KEGG: bmj:BMULJ_04355 hypothetical protein; SPTR: uncharacterized protein YP_004372371.1 KEGG: ccu:Ccur_02370 hypothetical protein; SPTR: uncharacterized protein YP_004372372.1 KEGG: apv:Apar_0978 hypothetical protein; SPTR: uncharacterized protein YP_004372373.1 COGs: COG3764 Sortase (surface protein transpeptidase); InterPro IPR005754; KEGG: bca:BCE_1805 sortase family protein; PFAM: peptidase C60 sortase A and B; SPTR: Sortase family protein; TIGRFAM: sortase family protein; PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_004372374.1 COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 018303:IPR006415:IPR001757; KEGG: lla:L85514 cation-transporting P-ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation-transporting P-ATPase; TIGRFAM: magnesium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase YP_004372375.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740; KEGG: smf:Smon_0914 protein of unknown function DUF161; PFAM: protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284 YP_004372376.1 KEGG: ele:Elen_2186 hypothetical protein; SPTR: uncharacterized protein YP_004372377.1 COGs: COG1696 membrane protein involved in D-alanine export; InterPro IPR004299; KEGG: ele:Elen_2185 membrane bound O-acyl transferase MBOAT family protein; PFAM: membrane bound O-acyl transferase MBOAT family protein; SPTR: Membrane bound O-acyl transferase MBOAT family protein; PFAM: MBOAT family YP_004372378.1 KEGG: ele:Elen_2184 hypothetical protein; SPTR: Phosphopantetheine attachment site; PFAM: Phosphopantetheine attachment site YP_004372379.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR000183; KEGG: ele:Elen_2183 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Diaminopimelate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain YP_004372380.1 COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterPro IPR000873:IPR020845:IPR010071; KEGG: shi:Shel_17200 non-ribosomal peptide synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Non-ribosomal peptide synthetase modules and related proteins; TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-binding enzyme; TIGRFAM: amino acid adenylation domain YP_004372381.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003661:IPR003594:IPR004358; KEGG: ele:Elen_2180 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004372382.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ele:Elen_2179 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004372383.1 COGs: COG4487 conserved hypothetical protein; InterPro IPR019219; KEGG: ele:Elen_1799 hypothetical protein; PFAM: Protein of unknown function DUF2130; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2130) YP_004372384.1 InterPro IPR011701; KEGG: rsl:RPSI07_mp0928 major facilitator superfamily multidrug transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004372385.1 COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525; KEGG: bvi:Bcep1808_2164 DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm) YP_004372386.1 KEGG: bln:Blon_0091 hypothetical protein; SPTR: uncharacterized protein YP_004372387.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: eat:EAT1b_2257 phophonate C-P lyase system transcriptional regulator PhnF, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain-containing protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372388.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: esi:Exig_0480 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain-containing protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372389.1 KEGG: ele:Elen_2138 hypothetical protein; SPTR: uncharacterized protein YP_004372390.1 KEGG: cbe:Cbei_2688 GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase YP_004372391.1 COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: cvi:CV_2920 hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004372392.1 InterPro IPR003749:IPR010035; KEGG: ele:Elen_1749 thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004372393.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR012729; KEGG: ele:Elen_1748 thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: Thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: ThiF family; TIGRFAM: thiamine biosynthesis protein ThiF, family 2 YP_004372394.1 COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; InterPro IPR008867; KEGG: ele:Elen_1747 thiazole biosynthesis family protein; PFAM: thiazole biosynthesis family protein; SPTR: Thiazole biosynthesis family protein; PFAM: Thiazole biosynthesis protein ThiG YP_004372395.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: ele:Elen_1745 thiamine monophosphate synthase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004372396.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: ele:Elen_1173 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004372397.1 KEGG: ele:Elen_1174 hypothetical protein; SPTR: uncharacterized protein YP_004372398.1 KEGG: mba:Mbar_A1995 cell surface protein; SPTR: uncharacterized protein YP_004372399.1 KEGG: pno:SNOG_02999 hypothetical protein; SPTR: Divergent AAA domain protein YP_004372400.1 KEGG: tva:TVAG_154640 surface antigen BspA-like; SPTR: uncharacterized protein YP_004372401.1 InterPro IPR001899:IPR008454:IPR019948:IPR019931; KEGG: ccu:Ccur_00810 Cna protein B-type domain-containing protein; PFAM: Cna B domain protein; Gram-positive anchor; SPTR: Cna protein B-type domain-containing protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Cna protein B-type domain; TIGRFAM: LPXTG-motif cell wall anchor domain YP_004372402.1 COGs: COG3764 Sortase (surface protein transpeptidase); InterPro IPR005754; KEGG: ccu:Ccur_00840 sortase family protein, LPXTG-site transpeptidase; PFAM: peptidase C60 sortase A and B; SPTR: Sortase family protein, LPXTG-site transpeptidase; TIGRFAM: sortase family protein; PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_004372403.1 COGs: COG3142 Uncharacterized protein involved in copper resistance; InterPro IPR005627; KEGG: efa:EF2667 copper homeostasis protein, PFAM: CutC family protein; SPTR: Copper resistance protein; PFAM: CutC family YP_004372404.1 KEGG: sml:Smlt2406 hypothetical protein; SPTR: uncharacterized protein YP_004372405.1 COGs: COG2217 Cation transport ATPase; InterProIPR008250:IPR005834:IPR018303:IPR000150:IPR 001757:IPR001756:IPR006403:IPR006416; KEGG: bts:Btus_2669 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004372406.1 COGs: COG2836 conserved hypothetical protein; InterPro IPR006121; KEGG: cpy:Cphy_2119 heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein YP_004372407.1 KEGG: kfl:Kfla_6991 hypothetical protein; SPTR: LigA YP_004372408.1 KEGG: blt:Balat_0256 hypothetical protein; SPTR: uncharacterized protein YP_004372409.1 COGs: COG1528 Ferritin-like protein; InterPro IPR009040:IPR008331; KEGG: apv:Apar_0301 ferritin Dps family protein; PFAM: Ferritin Dps family protein; SPTR: uncharacterized protein; PFAM: Ferritin-like domain YP_004372410.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020058:IPR001412:IPR020060; KEGG: apv:Apar_1332 glutamate--tRNA ligase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: uncharacterized protein; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-queuosine tRNA(Asp) synthetase YP_004372411.1 KEGG: ddi:DDB_G0271832 hypothetical protein; SPTR: uncharacterized protein YP_004372412.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: apv:Apar_0324 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372413.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: apv:Apar_0325 PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372414.1 COGs: COG3037 conserved hypothetical protein; KEGG: apv:Apar_0326 PTS system ascorbate-specific transporter subunit IIC; SPTR: sugar-specific permease SgaT/UlaA; PFAM: PTS system sugar-specific permease component; TC 4.A.7 YP_004372415.1 InterPro IPR003501; KEGG: apv:Apar_0327 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TC 4.A.7 YP_004372416.1 KEGG: apv:Apar_0328 FG-GAP repeat protein; SPTR: FG-GAP repeat protein YP_004372417.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: apv:Apar_0329 L-ascorbate 6-phosphate lactonase; SPTR: L-ascorbate 6-phosphate lactonase YP_004372418.1 COGs: COG3623 L-xylulose-5-phosphate 3-epimerase; InterPro IPR012307:IPR004560; KEGG: apv:Apar_0331 L-xylulose 5-phosphate 3-epimerase; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: L-ribulose-5-phosphate 3-epimerase; SPTR: Hexulose-6-phosphate isomerase; TIGRFAM: hexulose-6-phosphate isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: hexulose-6-phosphate isomerase YP_004372419.1 COGs: COG4936 sensor domain; InterPro IPR018060:IPR018771:IPR000005:IPR018062; KEGG: cbk:CLL_A0536 AraC family transcriptional regulator; PFAM: Transcription regulator,histidine kinase sensor-like; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Predicted histidine kinase sensor domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004372420.1 COGs: COG0371 Glycerol dehydrogenase; InterPro IPR001670:IPR016160:IPR018211:IPR016205; KEGG: bmq:BMQ_1805 glycerol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Glycerol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase YP_004372421.1 COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004006:IPR012736; KEGG: tte:TTE1997 dihydroxyacetone kinase; PFAM: Dak kinase; PRIAM: Glycerone kinase; SPTR: Dihydroxyacetone kinase; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak1 domain; TIGRFAM: dihydroxyacetone kinase, DhaK subunit YP_004372422.1 COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: pfr:PFREUD_23150 carboxylic ester hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Carboxylic ester hydrolase; PFAM: lysophospholipase; alpha/beta hydrolase fold YP_004372423.1 COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: cno:NT01CX_0688 dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; SPTR: Dihydroxyacetone kinase, L subunit; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit YP_004372424.1 COGs: COG3412 conserved hypothetical protein; InterPro IPR004701:IPR012844; KEGG: cbe:Cbei_2150 dihydroxyacetone kinase, phosphotransfer subunit; PFAM: PTS system fructose subfamily IIA component; SPTR: Dihydroxyacetone kinase, phosphotransfer subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; PFAM: PTS system fructose IIA component; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit YP_004372425.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR004184:IPR019777:IPR010098; KEGG: ect:ECIAI39_3038 formate acetyltransferase 2; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Pyruvate formate-lyase; TIGRFAM: pyruvate formate-lyase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: pyruvate formate-lyase YP_004372426.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR001989:IPR011352:IPR012839; KEGG: see:SNSL254_A4446 pyruvate formate lyase II activase; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: Pyruvate formate lyase II activase; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: Radical SAM superfamily; TIGRFAM: glycyl-radical enzyme activating protein family YP_004372427.1 KEGG: cin:100180760 similar to solute carrier family 44, member 2; SPTR: uncharacterized protein YP_004372428.1 COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR018060:IPR013096:IPR000005; KEGG: clj:CLJU_c13540 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Cupin domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004372429.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701:IPR001927; KEGG: clj:CLJU_c13530 sugar:sodium symporter; PFAM: major facilitator superfamily MFS_1; SPTR: Sugar (Glycoside-Pentoside-Hexuronide) transporter; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter YP_004372430.1 COGs: COG3533 conserved hypothetical protein; InterPro IPR012878; KEGG: clj:CLJU_c13520 hypothetical protein; PFAM: protein of unknown function DUF1680; SPTR: Protein of hypothetical function DUF1680; PFAM: glycosyl hydrolase of unknown function (DUF1680) YP_004372431.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076:IPR003953; KEGG: shi:Shel_07360 FAD-dependent dehydrogenase; PFAM: FAD dependent oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain YP_004372432.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR013011:IPR011608; KEGG: bpo:BP951000_1630 transcriptional antiterminator BglB; PFAM: PRD domain protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372433.1 COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: lgs:LEGAS_1790 PTS system lactose transporter subunit/cellobiose transporter subunit IIA; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit YP_004372434.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR001360:IPR017871:IPR018120; KEGG: lin:lin0328 hypothetical protein; PFAM: glycoside hydrolase family 1; PRIAM: Beta-glucosidase; SPTR: Glycosyl hydrolase; PFAM: Glycosyl hydrolase family 1 YP_004372435.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: lwe:lwe0274 PTS system, cellobiose-specific, IIB component; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004372436.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lwe:lwe0273 PTS system, IIC component; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: phosphotransferase system, cellobiose specific, IIC component; PTS system, lactose/cellobiose family IIC component YP_004372437.1 COGs: COG4907 membrane protein; InterPro IPR018702; KEGG: apv:Apar_1023 membrane protein-like protein; PFAM: Protein of unknown function DUF2207, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2207) YP_004372438.1 InterPro IPR000182; KEGG: bll:BLJ_1199 GCN5-like N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004372439.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982:IPR002695; KEGG: apv:Apar_1330 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_004372440.1 KEGG: apv:Apar_1329 hypothetical protein; SPTR: uncharacterized protein YP_004372441.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: apv:Apar_1082 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004372442.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003661:IPR003594; KEGG: ele:Elen_1416 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004372443.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016:IPR006015; KEGG: shi:Shel_19770 universal stress protein UspA-like protein; PFAM: UspA domain-containing protein; SPTR: uncharacterized protein; PFAM: Universal stress protein family YP_004372444.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: apv:Apar_0381 undecaprenyl-diphosphatase; PFAM: Bacitracin resistance protein BacA; SPTR: uncharacterized protein; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004372445.1 COGs: COG1015 Phosphopentomutase; InterPro IPR006124:IPR010045; KEGG: lrf:LAR_0106 phosphopentomutase; PFAM: metalloenzyme domain protein; PRIAM: Phosphopentomutase; SPTR: uncharacterized protein; TIGRFAM: phosphopentomutase; PFAM: Metalloenzyme superfamily; TIGRFAM: phosphopentomutase YP_004372446.1 COGs: COG0274 Deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: lrf:LAR_0105 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004372447.1 COGs: COG0213 Thymidine phosphorylase; InterProIPR017459:IPR000312:IPR013102:IPR017872:IPR 000053:IPR018090; KEGG: clo:HMPREF0868_0655 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Pyrimidine-nucleoside phosphorylase; SPTR: uncharacterized protein; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_004372448.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR016192:IPR006262; KEGG: apv:Apar_0146 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: uncharacterized protein; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004372449.1 COGs: COG1079 ABC-type transport system permease component; InterPro IPR001851; KEGG: apv:Apar_0145 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372450.1 COGs: COG4603 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: cbe:Cbei_3122 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372451.1 COGs: COG3845 ABC-type uncharacterized transport systems ATPase components; InterPro IPR003439:IPR017871:IPR003593; KEGG: apv:Apar_0143 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372452.1 COGs: COG1744 Uncharacterized ABC-type transport system periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: apv:Apar_0142 basic membrane lipoprotein; PFAM: basic membrane lipoprotein; SPTR: uncharacterized protein; PFAM: Basic membrane protein YP_004372453.1 COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845:IPR004402:IPR018016; KEGG: cpy:Cphy_0752 purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: uncharacterized protein; TIGRFAM: purine nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD) YP_004372454.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: apv:Apar_0382 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: uncharacterized protein; PFAM: UvrD/REP helicase YP_004372455.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: ele:Elen_0601 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily YP_004372456.1 InterPro IPR001647; KEGG: ccu:Ccur_00570 TetR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004372457.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501:IPR018313; KEGG: lcb:LCABL_30220 cellobiose PTS, EIIB; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Cellobiose PTS, EIIB; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004372458.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: lcz:LCAZH_2640 transcriptional regulator/sugar kinase; PFAM: ROK family protein; SPTR: Sugar kinase and transcription regulator; PFAM: ROK family YP_004372459.1 COGs: COG3538 conserved hypothetical protein; InterPro IPR008313; KEGG: lcz:LCAZH_2641 hypothetical protein; PFAM: Uncharacterised conserved protein UCP028846; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1237) YP_004372460.1 COGs: COG0383 Alpha-mannosidase; InterPro IPR000602:IPR011682; KEGG: lcz:LCAZH_2642 alpha-mannosidase; PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; SPTR: Alpha-mannosidase; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain YP_004372461.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352:IPR018087; KEGG: lcz:LCAZH_2643 PTS system cellobiose-specific transporter subunit IIC; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, cellobiose-specific IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004372462.1 COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004006:IPR004007; KEGG: tfu:Tfu_1716 dihydroxyacetone kinase; PFAM: Dak kinase; Dak phosphatase; PRIAM: Glycerone kinase; SPTR: uncharacterized protein; PFAM: DAK2 domain; Dak1 domain YP_004372463.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: apv:Apar_0154 PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: uncharacterized protein; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TC 4.A.5 YP_004372464.1 InterPro IPR013011:IPR003501; KEGG: sak:SAK_0525 PTS system, galactitol-specific IIB component, PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS family galactitol (Gat) porter component IIB; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TC 4.A.5 YP_004372465.1 COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR013014:IPR004703; KEGG: sak:SAK_0526 PTS system, galactitol-specific IIC component, PFAM: PTS system Galactitol-specific IIC component; SPTR: uncharacterized protein; PFAM: PTS system sugar-specific permease component YP_004372466.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: cth:Cthe_0319 class II aldolase/adducin-like protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin-like protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004372467.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: str:Sterm_3245 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372468.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cpy:Cphy_2742 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372469.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155; KEGG: trq:TRQ2_0516 NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; SPTR: NADH:flavin oxidoreductase/NADH oxidase; PFAM: NADH:flavin oxidoreductase / NADH oxidase family YP_004372470.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020904:IPR002347; KEGG: ske:Sked_06450 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004372471.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953; KEGG: trq:TRQ2_0517 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain YP_004372472.1 COGs: COG2364 membrane protein; KEGG: ckr:CKR_2402 hypothetical protein; SPTR: uncharacterized protein YP_004372473.1 COGs: COG0684 Demethylmenaquinone methyltransferase; InterPro IPR005493; KEGG: afn:Acfer_2031 dimethylmenaquinone methyltransferase; PFAM: Dimethylmenaquinone methyltransferase; SPTR: uncharacterized protein; PFAM: Demethylmenaquinone methyltransferase YP_004372474.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: sbl:Sbal_0768 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: uncharacterized protein; PFAM: Sodium:dicarboxylate symporter family YP_004372475.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: tye:THEYE_A0342 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: uncharacterized protein; PFAM: Aminotransferase class I and II YP_004372476.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tpd:Teth39_1153 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004372477.1 InterPro IPR011701:IPR005829; KEGG: bfa:Bfae_28350 arabinose efflux permease family protein; PFAM: major facilitator superfamily MFS_1; SPTR: Transporter, major facilitator family; PFAM: Major Facilitator Superfamily YP_004372478.1 InterPro IPR013737:IPR008902:IPR016007; KEGG: bfa:Bfae_29670 alpha-L-rhamnosidase; PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; SPTR: Alpha-L-rhamnosidase; PFAM: Bacterial alpha-L-rhamnosidase; Alpha-L-rhamnosidase N-terminal domain YP_004372479.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: cbe:Cbei_0763 RpiR family transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: uncharacterized protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004372480.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR013449; KEGG: cpy:Cphy_1146 rhamnulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Rhamnulokinase; TIGRFAM: rhamnulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: rhamnulokinase YP_004372481.1 COGs: COG4806 L-rhamnose isomerase; InterPro IPR009308; KEGG: bsu:BSU31180 L-rhamnose isomerase; PFAM: L-rhamnose isomerase; PRIAM: L-rhamnose isomerase; SPTR: uncharacterized protein; PFAM: L-rhamnose isomerase (RhaA); TIGRFAM: L-rhamnose isomerase YP_004372482.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: ele:Elen_1116 rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; PRIAM: Rhamnulose-1-phosphate aldolase; SPTR: uncharacterized protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: rhamnulose-1-phosphate aldolase YP_004372483.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118; KEGG: lrh:LGG_00057 mannitol dehydrogenase domain-containing protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Fructuronate reductase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_004372484.1 COGs: COG1312 D-mannonate dehydratase; InterPro IPR004628; KEGG: llm:llmg_0859 mannonate dehydratase; PFAM: Mannonate dehydratase; PRIAM: Mannonate dehydratase; SPTR: Mannonate dehydratase; TIGRFAM: mannonate dehydratase; PFAM: D-mannonate dehydratase (UxuA); TIGRFAM: mannonate dehydratase YP_004372485.1 COGs: COG1904 Glucuronate isomerase; InterPro IPR003766; KEGG: lsa:LSA0129 glucuronate isomerase; PFAM: Glucuronate isomerase; PRIAM: Glucuronate isomerase; SPTR: Glucuronate isomerase; PFAM: Glucuronate isomerase YP_004372486.1 COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: str:Sterm_4056 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004372487.1 InterPro IPR008040; KEGG: cpy:Cphy_3766 hydantoinase/oxoprolinase; PFAM: Hydantoinaseoxoprolinase domain protein; SPTR: Hydantoinase/oxoprolinase:Hydantoinaseoxoprolina se; PFAM: Hydantoinase/oxoprolinase N-terminal region YP_004372488.1 COGs: COG3661 Alpha-glucuronidase; InterPro IPR011100:IPR011099; KEGG: llm:llmg_1169 AguA protein; PFAM: Glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein; PRIAM: Alpha-glucuronidase; SPTR: AguA protein; PFAM: Glycosyl hydrolase family 67 C-terminus; Glycosyl hydrolase family 67 middle domain YP_004372489.1 COGs: COG2211 Na+/melibiose symporter and related transporter; KEGG: lla:L113994 sugar transport symporter; SPTR: Sugar transport symporter YP_004372490.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: llk:LLKF_1625 beta-1,4-xylosidase; PFAM: glycoside hydrolase family 43; PRIAM: Xylan 1,4-beta-xylosidase; SPTR: Beta-1,4-xylosidase; PFAM: Glycosyl hydrolases family 43 YP_004372491.1 InterPro IPR005181; KEGG: csc:Csac_0206 protein of unknown function DUF303, acetylesterase PFAM: protein of unknown function DUF303 acetylesterase; SPTR: sialate O-acetylesterase; PFAM: Domain of unknown function (DUF303); Glycosyl hydrolases family 2, sugar binding domain YP_004372492.1 COGs: COG4857 kinase; InterPro IPR009212; KEGG: cce:Ccel_1288 5-methylribose kinase; PRIAM: S-methyl-5-thioribose kinase; SPTR: uncharacterized protein; TIGRFAM: 5-methylthioribose kinase; PFAM: Phosphotransferase enzyme family; TIGRFAM: 5-methylthioribose kinase YP_004372493.1 COGs: COG0182 translation initiation factor 2B subunit eIF-2B alpha/beta/delta family; InterPro IPR000649:IPR005251:IPR011559; KEGG: cce:Ccel_1289 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: uncharacterized protein; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-methyl-5-thioribose-1-phosphate isomerase YP_004372494.1 COGs: COG2213 Phosphotransferase system mannitol-specific IIBC component; InterPro IPR013011:IPR013014:IPR003352:IPR003501; KEGG: sub:SUB0289 mannitol-specific phosphotransferase system (PTS), IIBC component; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system protein; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, mannitol-specific IIC component; TC 4.A.2.1.5 YP_004372495.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sub:SUB0288 sugar phosphotransferase system (PTS), IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Sugar phosphotransferase system (PTS), IIA component; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372496.1 COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118:IPR000669; KEGG: sub:SUB0287 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; PRIAM: Mannitol-1-phosphate 5-dehydrogenase; SPTR: Mannitol dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_004372497.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: sub:SUB0286 6-phospho-3-hexuloisomerase; PFAM: sugar isomerase (SIS); PRIAM: 6-phospho-3-hexuloisomerase; SPTR: Sugar isomerase; PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase YP_004372498.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: sub:SUB0285 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004372499.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: sub:SUB0284 DeoR family regulatory protein; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: Transcriptional Regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372500.1 COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: lpj:JDM1_0910 citrate lyase regulator; PFAM: sugar-binding domain-containing protein; SPTR: Citrate lyase regulator; PFAM: sugar-binding domain YP_004372501.1 COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302:IPR001891; KEGG: ooe:OEOE_0418 malate oxidoreductase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: oxaloacetate decarboxylase; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_004372502.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: ooe:OEOE_0419 citrate transporter; PFAM: Auxin Efflux Carrier; SPTR: citrate transporter; PFAM: Membrane transport protein YP_004372503.1 COGs: COG3053 Citrate lyase synthetase; InterPro IPR013166:IPR005216:IPR004821; KEGG: ooe:OEOE_0420 citrate lyase synthetase; PFAM: Citrate lyase ligase domain protein; PRIAM: [Citrate (pro-3S)-lyase] ligase; SMART: Citrate lyase ligase domain protein; SPTR: Citrate lyase synthetase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: Citrate lyase ligase C-terminal domain; TIGRFAM: [citrate (pro-3S)-lyase] ligase YP_004372504.1 COGs: COG3052 Citrate lyase gamma subunit; InterPro IPR006495; KEGG: ooe:OEOE_0421 citrate lyase subunit gamma; SPTR: Citrate lyase acyl carrier protein; TIGRFAM: citrate lyase acyl carrier protein; PFAM: Malonate decarboxylase delta subunit (MdcD); TIGRFAM: citrate lyase acyl carrier protein YP_004372505.1 COGs: COG2301 Citrate lyase beta subunit; InterPro IPR005000:IPR011206:IPR006475; KEGG: lpj:JDM1_0914 citrate lyase, beta chain; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: Citrate lyase, beta chain; TIGRFAM: citrate lyase, beta subunit; PFAM: HpcH/HpaI aldolase/citrate lyase family; TIGRFAM: citrate lyase, beta subunit YP_004372506.1 COGs: COG3051 Citrate lyase alpha subunit; InterPro IPR006472; KEGG: lpj:JDM1_0915 citrate lyase, alpha chain; PFAM: Citrate lyase alpha subunit; PRIAM: Citrate CoA-transferase; SPTR: Citrate lyase, alpha chain; TIGRFAM: citrate lyase, alpha subunit; PFAM: Citrate lyase, alpha subunit (CitF); TIGRFAM: citrate lyase, alpha subunit YP_004372507.1 COGs: COG3697 Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); InterPro IPR005551; KEGG: ooe:OEOE_0424 phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; SPTR: CitXG protein, includes Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX YP_004372508.1 COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736:IPR013838:IPR017551; KEGG: lpj:JDM1_0903 triphosphoribosyl-dephospho-CoA synthase; PFAM: triphosphoribosyl-dephospho-CoA protein; PRIAM: Triphosphoribosyl-dephospho-CoA synthase; SPTR: Triphosphoribosyl-dephospho-CoA synthase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG YP_004372509.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: bsu:BSU22120 Kdg operon transcriptional regulator (LacI family); PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004372510.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139; KEGG: dda:Dd703_1379 PfkB domain protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004372511.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: eel:EUBELI_01254 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004372512.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: sga:GALLO_1621 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: RpiR family transcriptional regulator protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004372513.1 KEGG: rca:Rcas_1384 hypothetical protein; SPTR: uncharacterized protein YP_004372514.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: ele:Elen_0761 formylmethionine deformylase; PFAM: formylmethionine deformylase; SPTR: Peptide deformylase; PFAM: Polypeptide deformylase YP_004372515.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: sub:SUB0180 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004372516.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: shi:Shel_26530 membrane protease subunit, stomatin/prohibitin; PFAM: band 7 protein; SMART: band 7 protein; SPTR: uncharacterized protein; PFAM: SPFH domain / Band 7 family YP_004372517.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148:IPR013189:IPR001362:IPR006232; KEGG: lki:LKI_10506 hypothetical protein; PFAM: Glycosyl hydrolase family 32 domain protein; SMART: glycoside hydrolase family 32; SPTR: Sucrose-6-phosphate hydrolase; TIGRFAM: sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolases family 32 C terminal; Glycosyl hydrolases family 32 N-terminal domain; TIGRFAM: sucrose-6-phosphate hydrolase YP_004372518.1 InterPro IPR020480:IPR000576; KEGG: lgs:LEGAS_0098 PTS system sucrose-specific transporter subunit EIIBC; SPTR: Sucrose transport protein; TIGRFAM: oligosaccharide/H+ symporter, major facilitator superfamily (MFS); PFAM: LacY proton/sugar symporter; TIGRFAM: oligosaccharide:H+ symporter YP_004372519.1 InterPro IPR000182; KEGG: san:gbs0028 GNAT family acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein YP_004372521.1 COGs: COG4581 Superfamily II RNA helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: ele:Elen_1453 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF3516); Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004372522.1 COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108; KEGG: msi:Msm_0965 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxyacyl-CoA dehydrogenase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_004372523.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; InterPro IPR003358; KEGG: apv:Apar_0291 methyltransferase; PFAM: methyltransferase; SPTR: uncharacterized protein; PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_004372524.1 KEGG: ccu:Ccur_11030 hypothetical protein; SPTR: uncharacterized protein YP_004372525.1 COGs: COG1243 Histone acetyltransferase; InterPro IPR000182:IPR007197:IPR006638; KEGG: shi:Shel_08040 histone acetyltransferase; PFAM: GCN5-related N-acetyltransferase; Radical SAM domain protein; PRIAM: Histone acetyltransferase; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family YP_004372526.1 COGs: COG0421 Spermidine synthase; InterPro IPR001045:IPR002160; KEGG: ccu:Ccur_04160 spermidine synthase; PFAM: Spermine synthase; SPTR: uncharacterized protein; PFAM: Spermine/spermidine synthase YP_004372527.1 COGs: COG1201 Lhr-like helicase; InterPro IPR014021:IPR001650:IPR011545:IPR014001; KEGG: afn:Acfer_0797 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004372528.1 KEGG: lcr:LCRIS_00477 biotin carboxylase; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2791) YP_004372529.1 KEGG: afn:Acfer_0795 hypothetical protein; SPTR: uncharacterized protein YP_004372530.1 COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR017926:IPR000728:IPR010918:IPR010141; KEGG: ele:Elen_0262 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II YP_004372531.1 COGs: COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR000917; KEGG: ele:Elen_1805 sulfatase; PFAM: sulfatase; SPTR: uncharacterized protein; PFAM: Sulfatase YP_004372532.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: dhd:Dhaf_4926 extracellular ligand-binding receptor; PFAM: Extracellular ligand-binding receptor; SPTR: uncharacterized protein; PFAM: Receptor family ligand binding region YP_004372533.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: dhd:Dhaf_4925 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372534.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: dhd:Dhaf_4924 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004372535.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: dsy:DSY5023 hypothetical protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004372536.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: dhd:Dhaf_4922 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372538.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterProIPR014021:IPR001650:IPR001667:IPR003156:IPR 011545:IPR014001:IPR004610; KEGG: apv:Apar_0519 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: uncharacterized protein; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHH family; DHHA1 domain; Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004372539.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR006674:IPR007685:IPR004095:IPR002912:IPR 003607:IPR004811; KEGG: apv:Apar_0520 (p)ppGpp synthetase I, SpoT/RelA; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; amino acid-binding ACT domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: RelA/SpoT family protein; PFAM: HD domain; ACT domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004372540.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001018; KEGG: apv:Apar_0521 beta-lactamase domain protein; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004372541.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: apv:Apar_0396 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004372542.1 COGs: COG0290 Translation initiation factor 3 (IF-3); InterPro IPR019814:IPR019815:IPR001288; KEGG: apv:Apar_0522 translation initiation factor IF-3; PFAM: Translation initiation factor 3-like; SPTR: uncharacterized protein; TIGRFAM: translation initiation factor IF-3; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004372543.1 InterPro IPR021137:IPR001706; KEGG: ele:Elen_1234 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004372544.1 COGs: COG0292 Ribosomal protein L20; InterPro IPR005813; KEGG: ele:Elen_1235 ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004372545.1 InterPro IPR005046:IPR011889; KEGG: efa:EF2248 hypothetical protein; PFAM: protein of unknown function DUF285 lipoprotein; SPTR: Predicted protein; TIGRFAM: lipoprotein; PFAM: Mycoplasma protein of unknown function, DUF285; TIGRFAM: bacterial surface protein 26-residue repeat YP_004372546.1 COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977; KEGG: apv:Apar_0948 dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; PRIAM: Dephospho-CoA kinase; SPTR: uncharacterized protein; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase YP_004372547.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR000189:IPR008258; KEGG: tte:TTE0876 lytic murein transglycosylase; PFAM: Lytic transglycosylase catalytic; SPTR: uncharacterized protein; PFAM: Transglycosylase SLT domain YP_004372548.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR001943:IPR014021:IPR001650:IPR014001:IPR 018247:IPR006935:IPR004807; KEGG: apv:Apar_0946 excinuclease ABC, B subunit; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC, B subunit; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004372549.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021:IPR001650:IPR014014:IPR014001:IPR 000629:IPR011545; KEGG: ccu:Ccur_05770 DNA/RNA helicase, superfamily II; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004372550.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: lrf:LAR_1436 hypothetical protein; PFAM: protein of unknown function DUF1212; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1212) YP_004372551.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: shi:Shel_04820 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004372552.1 COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926:IPR005856:IPR005859; KEGG: shi:Shel_04800 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004372553.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: eel:EUBELI_00637 cysteine desulfurase; PFAM: protein of unknown function UPF0074; SPTR: uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004372554.1 InterPro IPR007165; KEGG: ele:Elen_2907 membrane protein of unknown function; PFAM: membrane protein of unknown function; SPTR: uncharacterized protein; PFAM: Membrane protein of unknown function YP_004372555.1 COGs: COG4496 conserved hypothetical protein; InterPro IPR000831:IPR013368; KEGG: ccu:Ccur_01780 TrpR-related protein YerC/YecD; PFAM: Trp repressor; SPTR: uncharacterized protein; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD YP_004372556.1 KEGG: ele:Elen_1243 ATP-dependent nuclease subunit B-like protein; SPTR: uncharacterized protein YP_004372557.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014016:IPR014017:IPR000212; KEGG: ele:Elen_1244 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: uncharacterized protein; PFAM: UvrD/REP helicase YP_004372558.1 KEGG: lrl:LC705_02071 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF3284) YP_004372559.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593:IPR017871; KEGG: ele:Elen_2744 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372560.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: str:Sterm_1083 Cof-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily YP_004372561.1 COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001366:IPR018303:IPR018254:IPR 008250:IPR005834:IPR006404:IPR006416; KEGG: ele:Elen_1544 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004372562.1 InterPro IPR006121:IPR017969; KEGG: ele:Elen_1545 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: uncharacterized protein; PFAM: Heavy-metal-associated domain YP_004372563.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR018334; KEGG: ccu:Ccur_13760 transcriptional regulator, ArsR family; PFAM: ArsR family transcripitonal regulator; SMART: ArsR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, arsR family YP_004372564.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: shi:Shel_06580 predicted xylanase/chitin deacetylase; PFAM: polysaccharide deacetylase; SPTR: uncharacterized protein; PFAM: Polysaccharide deacetylase YP_004372565.1 KEGG: ccu:Ccur_06420 DNA polymerase III epsilon subunit-like 3'-5' exonuclease; SPTR: uncharacterized protein YP_004372567.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); InterProIPR014018:IPR011115:IPR020937:IPR011130:IPR 011116:IPR004027:IPR000185; KEGG: apv:Apar_1290 preprotein translocase, SecA subunit; PFAM: SecA DEAD domain protein; SecA preprotein cross-linking region; SecA Wing and Scaffold; SEC-C motif domain protein; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, SecA subunit; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004372568.1 COGs: COG1186 Protein chain release factor B; InterPro IPR000352:IPR005139:IPR004374; KEGG: apv:Apar_1289 peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; SPTR: uncharacterized protein; TIGRFAM: peptide chain release factor 2; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004372569.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: apv:Apar_1288 protein of unknown function DUF161; PFAM: Protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004372570.1 KEGG: car:cauri_1655 permease of the major facilitator superfamily; SPTR: Permease of the major facilitator superfamily YP_004372571.1 COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: apv:Apar_0333 transketolase domain protein; PFAM: Transketolase domain-containing protein; PRIAM: Transketolase; SPTR: Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain YP_004372572.1 COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR020826:IPR005475:IPR005476; KEGG: apv:Apar_0334 transketolase central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004372573.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003439:IPR003593:IPR017871:IPR005286; KEGG: apv:Apar_1279 cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE YP_004372574.1 COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: apv:Apar_1278 cell division protein FtsX; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372575.1 InterPro IPR019734:IPR013026; KEGG: apv:Apar_1273 tetratricopeptide domain protein; SPTR: uncharacterized protein YP_004372576.1 COGs: COG0691 tmRNA-binding protein; InterPro IPR000037; KEGG: apv:Apar_1272 SsrA-binding protein; PFAM: SmpB protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004372577.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: shi:Shel_24760 conserved protein of DIM6/NTAB family; PFAM: flavin reductase domain protein FMN-binding; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain YP_004372578.1 InterPro IPR004039; KEGG: apv:Apar_1271 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: uncharacterized protein; manually curated; PFAM: Rubredoxin YP_004372579.1 COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: ele:Elen_1060 amidohydrolase; PFAM: amidohydrolase; SPTR: uncharacterized protein; PFAM: Amidohydrolase family YP_004372580.1 KEGG: ele:Elen_0282 hypothetical protein; SPTR: uncharacterized protein YP_004372581.1 InterPro IPR006121; KEGG: mmh:Mmah_1005 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: uncharacterized protein; PFAM: Heavy-metal-associated domain YP_004372582.1 COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR001757:IPR001756:IPR018303:IPR 000169:IPR017969:IPR008250:IPR005834:IPR006403:IPR006416; KEGG: shi:Shel_01260 copper/silver-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004372583.1 COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: pru:PRU_1694 NADPH-dependent reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent reductase; PFAM: NADPH-dependent FMN reductase YP_004372584.1 COGs: COG0648 Endonuclease IV; InterPro IPR001719:IPR018246:IPR012307; KEGG: shi:Shel_21620 apurinic endonuclease APN1; PFAM: Xylose isomerase domain-containing protein TIM barrel; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: AP endonuclease family 2; SPTR: Probable endonuclease 4; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_004372585.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR018211:IPR001670; KEGG: shi:Shel_07410 Fe-dependent oxidoreductase, alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004372586.1 COGs: COG4198 conserved hypothetical protein; InterPro IPR008323; KEGG: eel:EUBELI_00766 hypothetical protein; PFAM: Uncharacterised conserved protein UCP033563; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1015) YP_004372587.1 InterPro IPR004843; KEGG: apv:Apar_0443 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004372588.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: ele:Elen_0415 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: Polysaccharide biosynthesis protein YP_004372589.1 COGs: COG1866 Phosphoenolpyruvate carboxykinase (ATP); InterPro IPR001272; KEGG: lba:Lebu_2281 phosphoenolpyruvate carboxykinase; PFAM: phosphoenolpyruvate carboxykinase (ATP); SPTR: uncharacterized protein; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP); PFAM: Phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP) YP_004372590.1 COGs: COG0588 Phosphoglycerate mutase 1; InterPro IPR001345:IPR013078:IPR005952; KEGG: shi:Shel_06510 phosphoglyceromutase; PFAM: Phosphoglycerate mutase; PRIAM: Bisphosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: Phosphoglycerate mutase family; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_004372591.1 COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR001497:IPR014048; KEGG: ele:Elen_1022 methylated-DNA/protein-cysteinemethyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: uncharacterized protein; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004372592.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480:IPR018481; KEGG: apv:Apar_0525 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 4 YP_004372593.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002306:IPR001412:IPR002305; KEGG: apv:Apar_0653 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004372594.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: lcr:LCRIS_01479 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004372595.1 COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR016431:IPR007197; KEGG: apv:Apar_0526 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: uncharacterized protein YP_004372596.1 KEGG: apv:Apar_0527 hypothetical protein; SPTR: uncharacterized protein YP_004372597.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR007229:IPR015977:IPR006405; KEGG: apv:Apar_0528 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase YP_004372598.1 COGs: COG0263 Glutamate 5-kinase; InterProIPR011529:IPR002478:IPR001057:IPR019797:IPR 001048:IPR005715; KEGG: ele:Elen_2010 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: uncharacterized protein; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase YP_004372599.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR012134:IPR015590:IPR000965; KEGG: ele:Elen_2009 gamma-glutamyl phosphate reductase; PFAM: Aldehyde Dehydrogenase; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase YP_004372600.1 COGs: COG2316 hydrolase (HD superfamily); KEGG: ele:Elen_2818 HDIG domain-containing protein; SPTR: HDIG domain-containing protein YP_004372601.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR001034:IPR002178:IPR013011:IPR011608; KEGG: tit:Thit_0259 PTS modulated transcriptional regulator, MtlR family; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRD domain protein; regulatory protein DeoR; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: DeoR-like helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372602.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: vvy:VVA1331 phosphotransferase system mannitol/fructose-specific IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Ascorbate-specific phosphotransferase enzyme iia component; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004372603.1 COGs: COG3037 conserved hypothetical protein; KEGG: apv:Apar_0170 sugar-specific permease SgaT/UlaA; SPTR: Ascorbate-specific PTS system enzyme IIC; PFAM: PTS system sugar-specific permease component; TC 4.A.7 YP_004372604.1 COGs: COG3414 Phosphotransferase system galactitol-specific IIB component; InterPro IPR013011:IPR003501; KEGG: apv:Apar_0171 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004372605.1 COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: apv:Apar_0332 transaldolase; PFAM: Transaldolase; SPTR: Transaldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004372606.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: pfr:PFREUD_01450 cell envelope-related function transcriptional attenuator common domain; PFAM: cell envelope-related transcriptional attenuator; SPTR: Cell envelope-related function transcriptional attenuator common domain; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004372607.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR001150:IPR005144:IPR012833; KEGG: shi:Shel_04760 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein; formate C-acetyltransferase glycine radical; PRIAM: Ribonucleoside-triphosphate reductase; SPTR: uncharacterized protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: Glycine radical; ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase YP_004372608.1 COGs: COG0602 Organic radical activating protein; InterPro IPR012837:IPR001989; KEGG: shi:Shel_04770 ribonucleoside-triphosphate reductase class III activase subunit; SPTR: uncharacterized protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein YP_004372609.1 COGs: COG0302 GTP cyclohydrolase I; InterPro IPR018234:IPR020602:IPR001474; KEGG: clj:CLJU_c06350 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004372610.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006157:IPR006156; KEGG: cno:NT01CX_0374 bifunctional folate synthesis protein; PFAM: dihydroneopterin aldolase; SPTR: uncharacterized protein; TIGRFAM: dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004372611.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: zmo:ZMO0010 hypothetical protein; PFAM: protein of unknown function DUF45; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF45 YP_004372612.1 COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: ele:Elen_2350 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: Peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_004372613.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: ele:Elen_2739 Cof-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004372614.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: llk:LLKF_2431 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcription regulator; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004372615.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: efa:EF3139 PTS system, IIC component; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: Phosphotransferase system PTS, sorbose-specific IIC subunit; PFAM: PTS system sorbose-specific iic component YP_004372616.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: efa:EF3138 PTS system, IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: PTS system, IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004372617.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: cbe:Cbei_2197 PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component; SPTR: PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component YP_004372618.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: lcb:LCABL_29240 PTS system, mannose-specific IIAB component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system, mannose-specific IIAB component; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004372619.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: clj:CLJU_c11620 D-isomer specific 2-hydroxyacid dehydrogenase family protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004372620.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: clj:CLJU_c11630 2-keto-3-deoxy-6-phosphogluconate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004372621.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR005834:IPR006402; KEGG: bid:Bind_0935 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD hydrolase, family IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004372622.1 KEGG: cbe:Cbei_2198 hypothetical protein; SPTR: uncharacterized protein YP_004372623.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: apv:Apar_1016 HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004372624.1 COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: mta:Moth_1378 hypothetical protein; PFAM: amino acid-binding ACT domain protein; SPTR: uncharacterized protein; PFAM: ACT domain YP_004372625.1 COGs: COG0254 Ribosomal protein L31; InterPro IPR002150; KEGG: ele:Elen_1117 ribosomal protein L31; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004372626.1 KEGG: ele:Elen_1466 YolD-like protein; SPTR: uncharacterized protein YP_004372627.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR017963:IPR001126; KEGG: ele:Elen_1465 UMUC domain protein DNA-repair protein; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: uncharacterized protein; PFAM: IMS family HHH motif; impB/mucB/samB family YP_004372628.1 InterPro IPR000326; KEGG: apv:Apar_1321 phosphoesterase PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Phosphoesterase PA-phosphatase related; PFAM: PAP2 superfamily YP_004372629.1 COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: bad:BAD_0231 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase YP_004372630.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR005834:IPR006402:IPR006439; KEGG: efa:EF0369 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004372631.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: cbe:Cbei_4797 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372632.1 COGs: COG1288 membrane protein; InterPro IPR018385; KEGG: cdl:CDR20291_1606 C4-dicarboxylate anaerobic carrier; PFAM: C4-dicarboxylate anaerobic carrier-like; SPTR: uncharacterized protein; PFAM: C4-dicarboxylate anaerobic carrier YP_004372633.1 COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: ele:Elen_2060 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: uncharacterized protein; PFAM: Amidohydrolase family YP_004372634.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: rcp:RCAP_rcp00008 protein FrlC; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel YP_004372635.1 COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: cbe:Cbei_4799 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain YP_004372636.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: cbe:Cbei_4798 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004372637.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: ctu:Ctu_38900 fructoselysine 6-kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase YP_004372638.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: hvo:HVO_A0503 amidohydrolase; PFAM: amidohydrolase 2; SPTR: uncharacterized protein; PFAM: Amidohydrolase YP_004372639.1 COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: pmx:PERMA_0015 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme YP_004372640.1 COGs: COG0434 TIM-barrel enzyme; InterPro IPR005137; KEGG: nca:Noca_3686 photosystem I assembly BtpA; PFAM: photosystem I assembly BtpA; SPTR: uncharacterized protein; PFAM: BtpA family; TIGRFAM: membrane complex biogenesis protein, BtpA family YP_004372641.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR018484:IPR018485; KEGG: ttr:Tter_2196 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004372642.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR012278:IPR001130; KEGG: ele:Elen_2262 TatD-related deoxyribonuclease; PFAM: TatD-related deoxyribonuclease; SPTR: uncharacterized protein; PFAM: TatD related DNase YP_004372643.1 COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: ele:Elen_2263 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: uncharacterized protein; PFAM: ThiF family YP_004372644.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593:IPR017871; KEGG: shi:Shel_22290 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family YP_004372645.1 KEGG: ele:Elen_2265 hypothetical protein; SPTR: uncharacterized protein YP_004372646.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: bad:BAD_0958 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 2 YP_004372647.1 COGs: COG0171 NAD synthase; InterPro IPR014445:IPR003010:IPR003694; KEGG: apv:Apar_0182 NAD+ synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: uncharacterized protein; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004372648.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557:IPR018177:IPR001236:IPR011304; KEGG: ele:Elen_2253 L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: L-lactate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: L-lactate dehydrogenase YP_004372649.1 KEGG: shi:Shel_21690 hypothetical protein; SPTR: uncharacterized protein YP_004372650.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR000719:IPR002290:IPR008266:IPR017442; KEGG: shi:Shel_21670 protein kinase family protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; SPTR: uncharacterized protein; PFAM: Protein kinase domain YP_004372651.1 COGs: COG3883 conserved hypothetical protein; KEGG: ccu:Ccur_04880 hypothetical protein; SPTR: uncharacterized protein YP_004372653.1 COGs: COG3919 ATP-grasp protein; InterPro IPR011761; KEGG: llc:LACR_2532 hypothetical protein; SPTR: uncharacterized protein YP_004372654.1 COGs: COG1794 Aspartate racemase; InterPro IPR018187:IPR015942:IPR004380; KEGG: pjd:Pjdr2_3258 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: uncharacterized protein; TIGRFAM: aspartate racemase; PFAM: Asp/Glu/Hydantoin racemase YP_004372655.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: eel:EUBELI_00626 ribonuclease III; PFAM: glycosyl transferase family 2; SPTR: Glycosyltransferases involved in cell wall biogenesis; PFAM: Glycosyl transferase family 2 YP_004372656.1 COGs: COG2246 membrane protein; InterPro IPR007267; KEGG: ele:Elen_1247 GtrA family protein; PFAM: GtrA family protein; SPTR: GtrA family protein; PFAM: GtrA-like protein YP_004372657.1 COGs: COG3855 conserved hypothetical protein; InterPro IPR009164; KEGG: eel:EUBELI_20473 fructose-1,6-bisphosphatase III; PFAM: fructose-16-bisphosphatase; PRIAM: Fructose-bisphosphatase; SPTR: uncharacterized protein; PFAM: Firmicute fructose-1,6-bisphosphatase YP_004372658.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dap:Dacet_1946 nitroreductase; PFAM: nitroreductase; SPTR: Nitroreductase; PFAM: Nitroreductase family YP_004372660.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ttr:Tter_2695 RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; SPTR: uncharacterized protein; PFAM: NOL1/NOP2/sun family YP_004372661.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: gva:HMPREF0424_0614 cobalt transport protein; PFAM: cobalt transport protein; SPTR: uncharacterized protein; PFAM: Cobalt transport protein YP_004372662.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR003593:IPR017871; KEGG: apv:Apar_0681 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal YP_004372663.1 InterPro IPR001917; KEGG: apv:Apar_0680 hypothetical protein; SPTR: uncharacterized protein YP_004372664.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206; KEGG: apv:Apar_0638 diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain YP_004372665.1 COGs: COG0349 Ribonuclease D; InterPro IPR002121:IPR002562:IPR006292; KEGG: apv:Apar_0639 ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain protein; PRIAM: Ribonuclease D; SMART: 3'-5' exonuclease; HRDC domain protein; SPTR: uncharacterized protein; TIGRFAM: ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D YP_004372666.1 COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: apv:Apar_0640 peptidase membrane zinc metallopeptidase PFAM: peptidase membrane zinc metallopeptidase; SPTR: uncharacterized protein; PFAM: neutral zinc metallopeptidase YP_004372667.1 COGs: COG1570 Exonuclease VII large subunit; InterPro IPR002034:IPR004365:IPR020579:IPR003753; KEGG: apv:Apar_0641 exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit-like; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: uncharacterized protein; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_004372668.1 InterPro IPR003761; KEGG: apv:Apar_0642 exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_004372669.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310:IPR019808; KEGG: apv:Apar_0643 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: uncharacterized protein; PFAM: HIT domain YP_004372670.1 COGs: COG0282 Acetate kinase; InterPro IPR004372:IPR000890; KEGG: apv:Apar_0644 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: uncharacterized protein; TIGRFAM: acetate kinase; PFAM: Acetokinase family; TIGRFAM: acetate kinase YP_004372671.1 COGs: COG0280 Phosphotransacetylase; InterPro IPR012147:IPR002505:IPR004614; KEGG: apv:Apar_0646 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: Phosphate acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase YP_004372672.1 COGs: COG0562 UDP-galactopyranose mutase; InterPro IPR006076:IPR015899:IPR004379; KEGG: apv:Apar_0647 UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like; FAD dependent oxidoreductase; PRIAM: UDP-galactopyranose mutase; SPTR: uncharacterized protein; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase; FAD dependent oxidoreductase; TIGRFAM: UDP-galactopyranose mutase YP_004372673.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: apv:Apar_0648 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 2 YP_004372674.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: apv:Apar_0649 maf protein; PFAM: Maf family protein; SPTR: uncharacterized protein; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004372675.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR002792:IPR010280:IPR001566; KEGG: apv:Apar_0652 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; SPTR: uncharacterized protein; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004372676.1 COGs: COG0855 Polyphosphate kinase; InterPro IPR003414; KEGG: ele:Elen_0719 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: Polyphosphate kinase; TIGRFAM: Polyphosphate kinase; PFAM: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004372677.1 COGs: COG2235 Arginine deiminase; InterPro IPR003876:IPR003198; KEGG: shi:Shel_02360 arginine deiminase; PFAM: amidinotransferase; PRIAM: Arginine deiminase; SPTR: Arginine deiminase; TIGRFAM: arginine deiminase; PFAM: Amidinotransferase; TIGRFAM: arginine deiminase YP_004372678.1 COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR002292:IPR006130:IPR006132:IPR006131; KEGG: shi:Shel_02370 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: uncharacterized protein; TIGRFAM: ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004372679.1 COGs: COG4868 conserved hypothetical protein; InterPro IPR004827:IPR014999; KEGG: blj:BLD_0715 hypothetical protein; PFAM: Domain of unknown function DUF1846; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1846) YP_004372680.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR017926:IPR017456:IPR000991:IPR004468; KEGG: apv:Apar_0475 CTP synthetase; PFAM: CTP synthase-like; glutamine amidotransferase class-I; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004372681.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: apv:Apar_0476 tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: uncharacterized protein; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004372682.1 COGs: COG2001 conserved hypothetical protein; InterPro IPR020603:IPR003444; KEGG: ccu:Ccur_09580 hypothetical protein; PFAM: MraZ domain; SPTR: uncharacterized protein; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004372683.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: apv:Apar_0478 S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004372684.1 KEGG: apv:Apar_0479 hypothetical protein; SPTR: uncharacterized protein YP_004372685.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460; KEGG: apv:Apar_0480 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; SPTR: uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_004372686.1 COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR000713:IPR013221:IPR004101:IPR005863; KEGG: apv:Apar_0481 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-d iaminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_004372687.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018480:IPR018481:IPR003524; KEGG: apv:Apar_0482 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4, conserved region; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR: uncharacterized protein; TIGRFAM:phospho-N-acetylmuramoyl-pentapeptide-trans ferase; PFAM: Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; Glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004372688.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR013221:IPR004101:IPR005762; KEGG: apv:Apar_0483 UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004372689.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: apv:Apar_0484 cell cycle protein; PFAM: cell cycle protein; SPTR: uncharacterized protein; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW YP_004372690.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR004276:IPR007235:IPR006009; KEGG: apv:Apar_0485 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; SPTR: uncharacterized protein; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004372691.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221:IPR004101:IPR005758; KEGG: apv:Apar_0486 UDP-N-acetylmuramate/alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate/alanine ligase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004372692.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR016166:IPR006094:IPR011601:IPR003170; KEGG: apv:Apar_0487 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain-containing protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004372693.1 COGs: COG1589 Cell division septal protein; InterPro IPR013685; KEGG: apv:Apar_0488 polypeptide-transport-associated domain protein FtsQ-type; PFAM: Polypeptide-transport-associated domain protein FtsQ-type; SPTR: uncharacterized protein; PFAM: POTRA domain, FtsQ-type YP_004372695.1 COGs: COG0206 Cell division GTPase; InterPro IPR000158:IPR020805:IPR003008:IPR018316; KEGG: apv:Apar_0489 cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004372696.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: apv:Apar_0490 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004372697.1 COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: dev:DhcVS_146 phosphate ABC transporter, phosphate-binding protein; SPTR: uncharacterized protein; TIGRFAM: phosphate binding protein; TIGRFAM: phosphate binding protein YP_004372698.1 COGs: COG0573 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR011864; KEGG: aoe:Clos_0267 phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC; phosphate ABC transporter, permease protein PstA YP_004372699.1 COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR000515:IPR005672; KEGG: csc:Csac_1612 phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA YP_004372700.1 COGs: COG1117 ABC-type phosphate transport system ATPase component; InterProIPR003439:IPR015850:IPR003593:IPR017871:IPR 005670; KEGG: aoe:Clos_0269 phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_004372701.1 COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170; KEGG: hor:Hore_21540 phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SPTR: uncharacterized protein; PFAM: PhoU domain YP_004372702.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR011078:IPR001608; KEGG: apv:Apar_0491 alanine racemase domain protein; PFAM: alanine racemase domain protein; SPTR: uncharacterized protein; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004372703.1 InterPro IPR007561; KEGG: apv:Apar_0492 protein of unknown function DUF552; PFAM: protein of unknown function DUF552; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF552) YP_004372704.1 InterPro IPR003425; KEGG: ccu:Ccur_09420 YGGT family protein; PFAM: protein of unknown function YGGT; SPTR: YlmG protein; manually curated; PFAM: YGGT family YP_004372705.1 InterPro IPR007793:IPR019933; KEGG: apv:Apar_0494 DivIVA family protein; PFAM: DivIVA family protein; SPTR: uncharacterized protein; TIGRFAM: DivIVA domain; PFAM: DivIVA protein; TIGRFAM: DivIVA domain YP_004372706.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR012770; KEGG: apv:Apar_1334 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Trehalose operon repressor; TIGRFAM: trehalose operon repressor; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; TIGRFAM: trehalose operon repressor, B. subtilis-type YP_004372707.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR018113:IPR003352:IPR 011296:IPR011535; KEGG: cbe:Cbei_2320 PTS system, trehalose-specific IIBC subunit; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, trehalose-specific, IIBC component; TIGRFAM: PTS system, trehalose-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB; TIGRFAM: PTS system, trehalose-specific IIBC component; PTS system, glucose-like IIB component YP_004372708.1 COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: apv:Apar_1336 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Trehalose-6-phosphate hydrolase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: alpha,alpha-phosphotrehalase YP_004372709.1 KEGG: spv:SPH_0071 hypothetical protein; SPTR: ORF2 YP_004372710.1 KEGG: cms:CMS_1462 peptidoglycan associated protein; SPTR: peptidoglycan associated protein YP_004372711.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR001387:IPR019759; KEGG: apv:Apar_0551 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Peptidase S24/S26A/S26B, conserved region; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Helix-turn-helix; Peptidase S24-like YP_004372712.1 KEGG: hvo:HVO_0689 chromosome segregation protein SMC; SPTR: Chromosome segregation protein SMC YP_004372713.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR001498; KEGG: apv:Apar_0903 protein of unknown function UPF0029; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family YP_004372714.1 InterPro IPR010181; KEGG: ele:Elen_2296 C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein; SPTR: uncharacterized protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: redox-active protein (C_GCAxxG_C_C); TIGRFAM: C_GCAxxG_C_C family probable redox protein YP_004372715.1 COGs: COG2267 Lysophospholipase; InterPro IPR001412:IPR000073; KEGG: ele:Elen_1032 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: lysophospholipase; alpha/beta hydrolase fold YP_004372716.1 COGs: COG1970 Large-conductance mechanosensitive channel; InterPro IPR001185:IPR019823; KEGG: apv:Apar_0316 large conductance mechanosensitive channel protein; PFAM: large-conductance mechanosensitive channel; SPTR: Large conductance mechanosensitive channel protein; TIGRFAM: large conductance mechanosensitive channel protein; PFAM: Large-conductance mechanosensitive channel, MscL; TIGRFAM: large conductance mechanosensitive channel protein YP_004372717.1 KEGG: ctp:CTRG_00041 hypothetical protein; SPTR: Merozoite surface protein 2 YP_004372718.1 COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: shi:Shel_11690 conserved protein of unknown function BmrU; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: uncharacterized protein; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004372719.1 InterPro IPR001647; KEGG: lbf:LBF_0720 AcrR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004372720.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211:IPR001670; KEGG: dsy:DSY1101 hypothetical protein; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004372721.1 InterPro IPR011701; KEGG: pjd:Pjdr2_1889 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004372722.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362:IPR006095:IPR006097:IPR006096; KEGG: chl:Chy400_2231 Glu/Leu/Phe/Val dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: uncharacterized protein; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004372723.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: pjd:Pjdr2_1888 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_004372724.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: pjd:Pjdr2_1890 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004372725.1 COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: pjd:Pjdr2_1891 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III YP_004372727.1 KEGG: bld:BLi04305 hypothetical protein; SPTR: uncharacterized protein YP_004372728.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: bln:Blon_0436 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004372729.1 KEGG: apv:Apar_0406 hypothetical protein; SPTR: uncharacterized protein YP_004372730.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: apv:Apar_0407 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter YP_004372731.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362:IPR006095:IPR006097:IPR006096; KEGG: ccu:Ccur_07080 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004372732.1 InterPro IPR003675; KEGG: cpr:CPR_0234 CAAX amino terminal protease family protein; PFAM: Abortive infection protein; SPTR: uncharacterized protein; PFAM: CAAX amino terminal protease family YP_004372733.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR005215:IPR008881:IPR008880; KEGG: apv:Apar_0614 trigger factor; PFAM: trigger factor domain-containing protein; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: Bacterial trigger factor protein (TF) C-terminus; Bacterial trigger factor protein (TF); TIGRFAM: trigger factor YP_004372734.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907:IPR018215; KEGG: apv:Apar_0615 endopeptidase Clp; PFAM: peptidase S14 ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004372735.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR003593:IPR010603:IPR013093:IPR019489:IPR 004487; KEGG: apv:Apar_0616 ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004372736.1 COGs: COG0525 Valyl-tRNA synthetase; InterProIPR019754:IPR001412:IPR002300:IPR013155:IPR 019499:IPR002303; KEGG: apv:Apar_0620 valyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; SPTR: uncharacterized protein; TIGRFAM: valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004372737.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: bmq:BMQ_4506 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004372738.1 COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR005834:IPR006402; KEGG: cvi:CV_2924 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Probable hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004372739.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR001645; KEGG: apv:Apar_0625 FolC bifunctional protein; PFAM: Mur ligase middle domain protein; SPTR: uncharacterized protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004372740.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR010140; KEGG: bpo:BP951000_0752 histidinol-phosphatase-like protein; PFAM: PHP domain protein; SPTR: uncharacterized protein; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family YP_004372741.1 COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR013027:IPR001155:IPR001327; KEGG: clj:CLJU_c29840 enoate reductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family YP_004372742.1 KEGG: apv:Apar_0626 hypothetical protein; SPTR: uncharacterized protein YP_004372743.1 COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR006195:IPR018158:IPR004095:IPR012947:IPR 002314:IPR004154:IPR002320; KEGG: ele:Elen_1907 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; TGS domain-containing protein; Anticodon-binding domain protein; SPTR: Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TGS domain; TIGRFAM: threonyl-tRNA synthetase YP_004372744.1 COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR006650:IPR000277; KEGG: xce:Xcel_2638 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: uncharacterized protein; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004372745.1 COGs: COG0207 Thymidylate synthase; InterPro IPR000398; KEGG: apv:Apar_0632 thymidylate synthase; PFAM: thymidylate synthase; PRIAM: Thymidylate synthase; SPTR: uncharacterized protein; TIGRFAM: thymidylate synthase; PFAM: Thymidylate synthase; TIGRFAM: thymidylate synthase YP_004372746.1 COGs: COG0262 Dihydrofolate reductase; InterPro IPR001796:IPR012259; KEGG: apv:Apar_0631 dihydrofolate reductase region; PFAM: dihydrofolate reductase region; SPTR: uncharacterized protein; PFAM: Dihydrofolate reductase YP_004372747.1 KEGG: apv:Apar_0227 flavodoxin; SPTR: uncharacterized protein YP_004372748.1 COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: shi:Shel_05470 rRNA methylase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: uncharacterized protein; PFAM: SpoU rRNA Methylase family YP_004372749.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR003593:IPR003960:IPR003959:IPR000642:IPR 005936; KEGG: apv:Apar_0842 ATP-dependent metalloprotease FtsH; PFAM: AAA ATPase central domain protein; peptidase M41; PRIAM: Microtubule-severing ATPase; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004372750.1 COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR003583:IPR019554:IPR000445:IPR004509; KEGG: ach:Achl_1982 competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: uncharacterized protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Helix-hairpin-helix motif; SLBB domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_004372751.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: apv:Apar_0804 ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; SPTR: uncharacterized protein; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_004372752.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372:IPR005790; KEGG: ele:Elen_1655 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004372753.1 COGs: COG0268 Ribosomal protein S20; InterPro IPR002583; KEGG: apv:Apar_0802 ribosomal protein S20; PFAM: ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: ribosomal protein S20; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004372754.1 COGs: COG0481 Membrane GTPase LepA; InterProIPR000795:IPR000640:IPR013842:IPR005225:IPR 006297; KEGG: ele:Elen_1652 GTP-binding protein LepA; PFAM: GTP-binding protein LepA domain protein; protein synthesis factor GTP-binding; elongation factor G domain-containing protein; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004372755.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR004652; KEGG: apv:Apar_0800 TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; SPTR: uncharacterized protein; TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, nifR3 family YP_004372756.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR010723:IPR004559; KEGG: apv:Apar_0799 oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase YP_004372757.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR001623:IPR001305:IPR003095:IPR018253:IPR 002939; KEGG: apv:Apar_0797 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; DnaJ central domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ central domain (4 repeats); DnaJ domain YP_004372758.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR001623:IPR001305:IPR003095:IPR018253:IPR 002939:IPR012724; KEGG: apv:Apar_0796 chaperone protein DnaJ; PFAM: heat shock protein DnaJ domain protein; DnaJ central domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ domain; DnaJ central domain (4 repeats); DnaJ C terminal region; TIGRFAM: chaperone protein DnaJ YP_004372759.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR006638:IPR020612:IPR007197:IPR 005839; KEGG: apv:Apar_0795 RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: radical SAM methylthiotransferase, MiaB/RimO family YP_004372761.1 COGs: COG0319 metal-dependent hydrolase; InterPro IPR020549:IPR002036; KEGG: apv:Apar_0793 protein of unknown function UPF0054; PFAM: protein of unknown function UPF0054; SPTR: metalloprotease COLINT_02278; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004372762.1 COGs: COG0818 Diacylglycerol kinase; InterPro IPR000829; KEGG: apv:Apar_0792 diacylglycerol kinase; PFAM: diacylglycerol kinase; SPTR: uncharacterized protein; PFAM: Prokaryotic diacylglycerol kinase YP_004372763.1 COGs: COG1159 GTPase; InterProIPR004044:IPR006073:IPR003593:IPR002917:IPR 005225:IPR005662; KEGG: apv:Apar_0791 GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: GTPase of unknown function; KH domain; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004372764.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); InterPro IPR003717; KEGG: apv:Apar_0790 DNA repair protein RecO; PFAM: Recombination protein O RecO; SPTR: uncharacterized protein; TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004372765.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR000103:IPR019575; KEGG: eel:EUBELI_00200 glutamate synthase (NADPH) small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: uncharacterized protein; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Pyridine nucleotide-disulphide oxidoreductase YP_004372766.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR017900:IPR000283:IPR 019574:IPR004108:IPR003149:IPR013352; KEGG: eel:EUBELI_00201 NADH dehydrogenase I chain G; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: uncharacterized protein; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 2Fe-2S iron-sulfur cluster binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only YP_004372767.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; KEGG: dhd:Dhaf_2612 hypothetical protein; SPTR: uncharacterized protein; PFAM: NMT1/THI5 like YP_004372768.1 KEGG: fps:FP0179 cell surface leucine-rich repeat-containing protein; SPTR: Probable cell surface protein (Leucine-rich repeat protein) YP_004372769.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439:IPR000515:IPR003593:IPR017871; KEGG: dhd:Dhaf_2613 binding-protein-dependent transport systems inner membrane component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter YP_004372770.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589:IPR005290; KEGG: apv:Apar_0789 ribosomal protein S15; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: ribosomal protein S15; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004372771.1 COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterProIPR012162:IPR004088:IPR003029:IPR004087:IPR 001247:IPR015847:IPR015848:IPR018111; KEGG: apv:Apar_0788 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding; K Homology, type 1, subgroup; RNA binding S1 domain protein; PRIAM: Polyribonucleotide nucleotidyltransferase; SMART: KH domain protein; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004372772.1 COGs: COG5495 conserved hypothetical protein; InterPro IPR018931; KEGG: ere:EUBREC_2502 hypothetical protein; PFAM: Domain of unknown function DUF2520; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF2520); Rossmann-like domain YP_004372773.1 COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: cno:NT01CX_1071 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_004372774.1 COGs: COG0414 Panthothenate synthetase; InterPro IPR003721; KEGG: cbe:Cbei_2609 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: pantoate/beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase YP_004372775.1 COGs: COG0853 Aspartate 1-decarboxylase; InterPro IPR003190; KEGG: efa:EF1858 aspartate alpha-decarboxylase; PFAM: aspartate decarboxylase; PRIAM: Aspartate 1-decarboxylase; SPTR: Aspartate 1-decarboxylase; TIGRFAM: aspartate 1-decarboxylase; PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004372776.1 KEGG: pyo:PY00381 hypothetical protein; SPTR: Zinc finger protein Glo3-like YP_004372777.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: pna:Pnap_2067 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: 2-keto-3-deoxygluconate kinase; PFAM: pfkB family carbohydrate kinase YP_004372778.1 COGs: COG0474 Cation transport ATPase; InterPro IPR001757:IPR018303:IPR008250:IPR005834; KEGG: ele:Elen_1182 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004372779.1 KEGG: apv:Apar_0667 hypothetical protein; SPTR: uncharacterized protein YP_004372780.1 InterPro IPR013026:IPR019734:IPR001440; KEGG: apv:Apar_0669 tetratricopeptide domain protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat YP_004372781.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: apv:Apar_0670 cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; SPTR: uncharacterized protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004372782.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR007221:IPR005223; KEGG: apv:Apar_0671 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: uncharacterized protein; TIGRFAM: rod shape-determining protein MreC; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004372783.1 InterPro IPR007227; KEGG: apv:Apar_0672 rod shape-determining protein MreD; SPTR: uncharacterized protein; TIGRFAM: rod shape-determining protein MreD; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD YP_004372784.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: apv:Apar_0673 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004372785.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: apv:Apar_0674 cell cycle protein; PFAM: cell cycle protein; SPTR: uncharacterized protein; PFAM: Cell cycle protein YP_004372786.1 KEGG: apv:Apar_0675 hypothetical protein; SPTR: uncharacterized protein YP_004372787.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006058:IPR006158:IPR007197; KEGG: apv:Apar_0676 radical SAM domain protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein YP_004372788.1 COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: apv:Apar_0677 hypothetical protein; PFAM: Protein of unknown function DUF2344; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); TIGRFAM: radical SAM-linked protein YP_004372789.1 COGs: COG0261 Ribosomal protein L21; InterPro IPR001787; KEGG: apv:Apar_0678 ribosomal protein L21; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004372790.1 COGs: COG0211 Ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: ele:Elen_2012 ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004372791.1 COGs: COG0536 GTPase; InterProIPR006073:IPR006074:IPR006169:IPR002917:IPR 015349:IPR014100; KEGG: apv:Apar_0683 GTP-binding protein Obg/CgtA; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; GTP1/OBG domain protein; SPTR: uncharacterized protein; TIGRFAM: GTP-binding protein Obg/CgtA; Obg family GTPase CgtA; PFAM: GTPase of unknown function; GTP1/OBG; Domain of unknown function (DUF1967); TIGRFAM: Obg family GTPase CgtA; Obg family GTPase CgtA, C-terminal extension YP_004372792.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820:IPR004821:IPR005248; KEGG: apv:Apar_0684 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004372793.1 COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR003607:IPR006674:IPR005249; KEGG: ele:Elen_2007 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; PFAM: HD domain; TIGRFAM: HD superfamily hydrolase of NAD metabolism YP_004372794.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: apv:Apar_0686 iojap-like protein; PFAM: Iojap-related protein; SPTR: uncharacterized protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004372795.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR017963:IPR005829:IPR001126; KEGG: apv:Apar_0687 DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: uncharacterized protein; PFAM: impB/mucB/samB family C-terminal; impB/mucB/samB family YP_004372796.1 COGs: COG0228 Ribosomal protein S16; InterPro IPR000307; KEGG: apv:Apar_0688 ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004372797.1 COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR004088; KEGG: apv:Apar_0689 RNA-binding protein (contains KH domain protein)-like protein; SPTR: uncharacterized protein; PFAM: KH domain YP_004372798.1 COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR011961; KEGG: apv:Apar_0690 16S rRNA-processing protein; SPTR: uncharacterized protein; TIGRFAM: 16S rRNA processing protein RimM; manually curated; PFAM: RimM N-terminal domain YP_004372799.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR002649:IPR016009; KEGG: shi:Shel_11000 tRNA (guanine37-N(1)-) methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004372800.1 COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: ccu:Ccur_00350 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: uncharacterized protein; TIGRFAM: signal peptidase I; PFAM: Peptidase S26; TIGRFAM: signal peptidase I, bacterial type YP_004372801.1 COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; InterPro IPR006194:IPR002310:IPR000408; KEGG: apv:Apar_0693 glycyl-tRNA synthetase subunit alpha; PFAM: glycyl-tRNA synthetase alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit YP_004372802.1 COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR006194:IPR002311:IPR008909:IPR015944; KEGG: apv:Apar_0694 glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain protein; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase beta subunit; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit YP_004372803.1 COGs: COG1806 conserved hypothetical protein; InterPro IPR005177; KEGG: ccu:Ccur_00380 hypothetical protein; PFAM: protein of unknown function DUF299; SPTR: phosphotransferase COLINT_02393; PFAM: Domain of unknown function (DUF299) YP_004372804.1 COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR010121:IPR018274:IPR000121:IPR002192:IPR 008279; KEGG: shi:Shel_11050 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: uncharacterized protein; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase YP_004372805.1 COGs: COG0335 Ribosomal protein L19; InterPro IPR001857:IPR018257; KEGG: apv:Apar_0698 ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004372806.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: apv:Apar_0699 ribonuclease H; PFAM: ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease; PFAM: Ribonuclease HII YP_004372807.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: apv:Apar_0700 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein YP_004372808.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR001208:IPR003593:IPR000523:IPR004482; KEGG: apv:Apar_0701 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_004372809.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: apv:Apar_0702 smf family protein; PFAM: SMF family protein; SPTR: uncharacterized protein; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004372810.1 COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; InterPro IPR002218:IPR004417; KEGG: apv:Apar_0703 gid protein; PFAM: glucose-inhibited division protein A; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferasetrmFO; TIGRFAM: gid protein; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase YP_004372811.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: apv:Apar_0704 integrase family protein; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: uncharacterized protein; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004372812.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR018130:IPR005706; KEGG: apv:Apar_0705 ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004372813.1 COGs: COG0264 Translation elongation factor Ts; InterPro IPR000449:IPR014039:IPR001816; KEGG: apv:Apar_0706 translation elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor Ts; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004372814.1 COGs: COG0528 Uridylate kinase; InterPro IPR011817:IPR001048:IPR015963; KEGG: ccu:Ccur_10930 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: uncharacterized protein; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_004372815.1 COGs: COG0233 Ribosome recycling factor; InterPro IPR002661:IPR015998; KEGG: apv:Apar_0708 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: uncharacterized protein; TIGRFAM: ribosome recycling factor; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004372816.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR018520:IPR001441; KEGG: apv:Apar_0709 undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: uncharacterized protein; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004372817.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: apv:Apar_0710 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: uncharacterized protein; PFAM: Cytidylyltransferase family YP_004372818.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821:IPR013512:IPR013644; KEGG: shi:Shel_23580 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004372819.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR001478:IPR008915; KEGG: apv:Apar_0712 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP YP_004372820.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR016425:IPR004588; KEGG: apv:Apar_0713 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: IspG family protein; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004372821.1 COGs: COG0442 Prolyl-tRNA synthetase; InterProIPR006195:IPR002316:IPR002314:IPR007214:IPR 004154:IPR004500; KEGG: apv:Apar_0714 prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); YbaK/prolyl-tRNA synthetase associated region; Anticodon-binding domain protein; SPTR: uncharacterized protein; TIGRFAM: prolyl-tRNA synthetase; PFAM: YbaK / prolyl-tRNA synthetases associated domain; Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II YP_004372822.1 InterPro IPR003838; KEGG: ele:Elen_2587 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004372823.1 KEGG: nth:Nther_1827 substrate-binding region of ABC-type glycine betaine transport system; SPTR: uncharacterized protein YP_004372824.1 COGs: COG4377 membrane protein; InterPro IPR011397; KEGG: bcy:Bcer98_3565 hypothetical protein; PFAM: protein of unknown function UCP033101; SPTR: membrane protein; PFAM: Predicted membrane protein (DUF2324) YP_004372825.1 KEGG: isc:IscW_ISCW018489 amino acid permease YP_004372826.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593:IPR017871; KEGG: apv:Apar_0719 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372827.1 KEGG: saq:Sare_4122 major facilitator transporter; SPTR: uncharacterized protein YP_004372828.1 COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: ele:Elen_1326 peptidase M50; PFAM: peptidase M50; SPTR: uncharacterized protein; PFAM: Peptidase family M50 YP_004372829.1 COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: apv:Apar_0721 chromosome segregation and condensation protein ScpA; PFAM: chromosome segregation and condensation protein ScpA; SPTR: uncharacterized protein; PFAM: ScpA/B protein YP_004372830.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: apv:Apar_0722 chromosome segregation and condensation protein, ScpB; PFAM: chromosome segregation and condensation protein ScpB; SPTR: uncharacterized protein; TIGRFAM: segregation and condensation protein B; PFAM: transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_004372831.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR018496:IPR006145:IPR000748; KEGG: ele:Elen_1330 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004372832.1 COGs: COG0283 Cytidylate kinase; InterPro IPR011994:IPR003136; KEGG: apv:Apar_0725 cytidylate kinase; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_004372833.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: apv:Apar_0725 cytidylate kinase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: uncharacterized protein; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004372834.1 COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: apv:Apar_0726 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004372835.1 COGs: COG1160 GTPase; InterPro IPR016484:IPR006073:IPR002917:IPR005225; KEGG: apv:Apar_0728 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004372836.1 COGs: COG0344 membrane protein; InterPro IPR003811:IPR020788; KEGG: ele:Elen_1338 protein of unknown function DUF205; PFAM: protein of unknown function DUF205; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004372837.1 COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR006168:IPR011128:IPR006109; KEGG: apv:Apar_0730 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus YP_004372838.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: apv:Apar_0731 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: uncharacterized protein; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004372839.1 COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192; KEGG: apv:Apar_0732 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: uncharacterized protein; PFAM: Aminotransferase class-V YP_004372840.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: ele:Elen_1349 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3) YP_004372841.1 COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: apv:Apar_0733 protein of unknown function DUF164; PFAM: protein of unknown function DUF164; SPTR: uncharacterized protein; PFAM: zinc ribbon domain YP_004372842.1 COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR003382:IPR007085:IPR005252; KEGG: ele:Elen_1562 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: uncharacterized protein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004372843.1 KEGG: blt:Balat_0930 hypothetical protein; SPTR: uncharacterized protein YP_004372844.1 KEGG: blt:Balat_0930 hypothetical protein; SPTR: uncharacterized protein YP_004372845.1 KEGG: rmr:Rmar_0489 membrane of secreted protein YP_004372846.1 KEGG: cms:CMS_0354 hypothetical protein; SPTR: uncharacterized protein YP_004372847.1 KEGG: sun:SUN_0732 hypothetical protein; SPTR: uncharacterized protein YP_004372848.1 COGs: COG0606 ATPase with chaperone activity; KEGG: apv:Apar_0701 Mg chelatase, subunit ChlI; SPTR: uncharacterized protein YP_004372849.1 KEGG: blj:BLD_1807 transposase; SPTR: Transposase YP_004372850.1 KEGG: son:SO_0859 sensory box histidine kinase/response regulator; SPTR: Sensory box histidine kinase/response regulator YP_004372851.1 KEGG: syp:SYNPCC7002_A1656 prolyl-tRNA synthetase; SPTR: Prolyl-tRNA synthetase YP_004372852.1 InterPro IPR012867; KEGG: ele:Elen_1294 protein of unknown function DUF1648; PFAM: protein of unknown function DUF1648; SPTR: Predicted integral membrane protein; PFAM: Protein of unknown function (DUF1648) YP_004372853.1 KEGG: ptm:GSPATT00001827001 hypothetical protein; SPTR: uncharacterized protein YP_004372854.1 InterPro IPR018656; KEGG: krh:KRH_07590 hypothetical protein; PFAM: Protein of unknown function DUF2087; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2087) YP_004372855.1 InterPro IPR006186:IPR004843; KEGG: spx:SPG_1990 Ser/Thr protein phosphatase family protein; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase YP_004372856.1 KEGG: pjd:Pjdr2_0698 outer membrane adhesin like proteiin; SPTR: uncharacterized protein YP_004372857.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR003353:IPR006327:IPR003352:IPR013011:IPR 013014; KEGG: lrl:LC705_00077 PTS system transporter subunit IICB; PFAM: phosphotransferase system EIIC; SPTR: PTS system, IICB component; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component YP_004372858.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR004715:IPR002178; KEGG: lrl:LC705_00078 PTS system transporter subunit IIA; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS system, IIA component; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; TC 4.A.2.1.8 YP_004372859.1 KEGG: lwe:lwe2314 hypothetical protein; SPTR: Complete genome YP_004372860.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000276:IPR000281:IPR001347; KEGG: lrh:LGG_00094 hypothetical protein; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: Predicted protein; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004372861.1 KEGG: art:Arth_0107 pH-dependent sodium/proton antiporter; SPTR: Na(+)/H(+) antiporter nhaA YP_004372862.1 KEGG: rme:Rmet_3400 major facilitator transporter; SPTR: Permease Membrane protein mosC Major facilitator superfamily MFS_1 YP_004372863.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lgs:LEGAS_1864 PTS system lactose transporter subunit/cellobiose transporter subunit IIC; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, lactose/cellobiose family IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004372864.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: apv:Apar_0078 glycoside hydrolase family 1; PFAM: glycoside hydrolase family 1; SPTR: Glycoside hydrolase family 1; PFAM: Glycosyl hydrolase family 1 YP_004372865.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: cbe:Cbei_4561 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004372866.1 COGs: COG0502 Biotin synthase; InterPro IPR005244:IPR006638:IPR007197; KEGG: cth:Cthe_1839 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE YP_004372867.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: ere:EUBREC_0235 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: uncharacterized protein; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH YP_004372868.1 COGs: COG1160 GTPase; InterPro IPR005225:IPR002917; KEGG: cth:Cthe_0042 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Iron-only hydrogenase maturation protein HydF; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain YP_004372869.1 KEGG: ere:EUBREC_0233 hypothetical protein; SPTR: Hypothetical transcriptional regulatory protein; TIGRFAM: iron-only hydrogenase system regulator YP_004372870.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650; KEGG: sth:STH1479 peptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain YP_004372871.1 KEGG: blj:BLD_0271 membrane protein; SPTR: uncharacterized protein YP_004372872.1 COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: cak:Caul_0319 ATPase BadF/BadG/BcrA/BcrD type; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: uncharacterized protein; PFAM: BadF/BadG/BcrA/BcrD ATPase family YP_004372873.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: bhy:BHWA1_01966 transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004372874.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ele:Elen_1230 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Probable fructose-bisphosphate aldolase 1; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004372875.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: lcb:LCABL_29410 AhaA protein (fragment); PFAM: PTS system fructose subfamily IIA component; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component YP_004372876.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: lrh:LGG_02747 PTS system mannose/fructose/sorbose-specific transporter subunit IIAB; PFAM: PTS system sorbose subfamily IIB component; SPTR: uncharacterized protein; PFAM: PTS system sorbose subfamily IIB component YP_004372877.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: lcb:LCABL_29390 C component PTS system mannose-specific enzyme II; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004372878.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: lrh:LGG_02745 PTS system mannose/fructose/sorbose-specific transporter subunit IID; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004372879.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: lcb:LCABL_29170 zinc-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase YP_004372880.1 KEGG: ere:EUBREC_0180 hypothetical protein; SPTR: uncharacterized protein YP_004372882.1 COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462; KEGG: apv:Apar_0749 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: uncharacterized protein; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004372883.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: apv:Apar_0753 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: FHA domain YP_004372884.1 InterPro IPR000551; KEGG: apv:Apar_0754 transcriptional regulator, MerR family; PFAM: MerR family transcripitonal regulator; SMART: MerR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: MerR family regulatory protein YP_004372885.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR005764:IPR000836; KEGG: shi:Shel_04860 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_004372886.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: clj:CLJU_c01500 hypothetical protein; PFAM: NLP/P60 protein; SPTR: uncharacterized protein; PFAM: NlpC/P60 family YP_004372887.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: apv:Apar_0756 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: uncharacterized protein; PFAM: NlpC/P60 family YP_004372888.1 COGs: COG1307 conserved hypothetical protein; InterPro IPR003797; KEGG: sga:GALLO_0386 hypothetical protein; PFAM: DegV family protein; SPTR: uncharacterized protein; TIGRFAM: degV family protein; PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: EDD domain protein, DegV family YP_004372889.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR000103:IPR013027; KEGG: apv:Apar_0765 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004372890.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR009695; KEGG: ele:Elen_1241 glycosyltransferase 28 domain protein; PFAM: Monogalactosyldiacylglycerol synthase; SPTR: uncharacterized protein; PFAM: Glycosyltransferase family 28 C-terminal domain; Monogalactosyldiacylglycerol (MGDG) synthase YP_004372891.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: apv:Apar_0766 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease; PFAM: Permease family YP_004372892.1 COGs: COG0756 dUTPase; InterPro IPR008181:IPR008180; KEGG: apv:Apar_0767 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; PRIAM: dUTP diphosphatase; SPTR: uncharacterized protein; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_004372893.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; InterPro IPR003796:IPR005144; KEGG: apv:Apar_0768 ATP-cone domain protein; PFAM: ATP-cone domain protein; SPTR: uncharacterized protein; PFAM: ATP cone domain; Transcription factor S-II (TFIIS); TIGRFAM: transcriptional regulator NrdR YP_004372894.1 InterPro IPR018392; KEGG: apv:Apar_0769 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SPTR: uncharacterized protein; PFAM: LysM domain YP_004372895.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006200:IPR006197:IPR006199:IPR019759; KEGG: apv:Apar_0770 SOS-response transcriptional repressor, LexA; PFAM: LexA DNA-binding domain protein; Peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004372896.1 COGs: COG3503 membrane protein; InterPro IPR012429; KEGG: apv:Apar_0771 protein of unknown function DUF1624; PFAM: protein of unknown function DUF1624; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1624) YP_004372897.1 COGs: COG2262 GTPase; InterPro IPR016496:IPR006073:IPR002917; KEGG: apv:Apar_0772 GTP-binding protein HflX; PFAM: GTP-binding protein HSR1-related; SPTR: uncharacterized protein; TIGRFAM: GTP-binding proten HflX; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX YP_004372898.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022:IPR002627; KEGG: apv:Apar_0773 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: uncharacterized protein; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase YP_004372899.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR006463:IPR020612:IPR006638:IPR 013848:IPR007197:IPR002792; KEGG: apv:Apar_0774 RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; protein of unknown function UPF0004 ; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase enzyme MiaB; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family YP_004372900.1 COGs: COG2359 conserved hypothetical protein; InterPro IPR007347; KEGG: apv:Apar_0775 stage V sporulation protein S; PFAM: Stage V sporulation protein S; SPTR: uncharacterized protein; PFAM: Stage V sporulation protein S (SpoVS) YP_004372901.1 InterPro IPR003594; KEGG: apv:Apar_0776 ATP-binding region ATPase domain protein; PFAM: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004372902.1 COGs: COG1418 HD superfamily hydrolase; InterProIPR017705:IPR006675:IPR004087:IPR003607:IPR 018111:IPR006674:IPR004088; KEGG: apv:Apar_0777 RNA binding metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; K Homology, type 1, subgroup; SMART: metal-dependent phosphohydrolase HD region; KH domain protein; SPTR: uncharacterized protein; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004372903.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: apv:Apar_0778 RecX family transcripitonal regulator; PFAM: RecX family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: RecX family YP_004372904.1 COGs: COG0468 RecA/RadA recombinase; InterProIPR013765:IPR020584:IPR003593:IPR001553:IPR 020588:IPR020587; KEGG: apv:Apar_0779 RecA protein; PFAM: RecA domain protein; SMART: AAA ATPase; SPTR: Protein recA; TIGRFAM: recA protein; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004372905.1 COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: ele:Elen_1620 CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; PFAM: CinA domain protein; SPTR: uncharacterized protein; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_004372906.1 COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: apv:Apar_0782 CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: uncharacterized protein; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_004372907.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR005840:IPR020612:IPR006638:IPR 013848:IPR007197; KEGG: apv:Apar_0783 MiaB-like tRNA modifying enzyme YliG; PFAM: Radical SAM domain protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family YP_004372908.1 COGs: COG1666 conserved hypothetical protein; InterPro IPR007551; KEGG: shi:Shel_10690 hypothetical protein; PFAM: protein of unknown function DUF520; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF520) YP_004372909.1 COGs: COG1426 conserved hypothetical protein; KEGG: apv:Apar_0785 XRE family transcriptional regulator; SPTR: uncharacterized protein YP_004372910.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: apv:Apar_0786 cell divisionFtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004372911.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR020578:IPR001587:IPR011108; KEGG: apv:Apar_0787 beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004372912.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR004604:IPR003395; KEGG: ele:Elen_2491 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: uncharacterized protein; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004372913.1 COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: apv:Apar_0473 ATP-NAD/AcoX kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: uncharacterized protein; PFAM: ATP-NAD kinase YP_004372914.1 COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002877; KEGG: apv:Apar_0472 hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: uncharacterized protein; TIGRFAM: hemolysin A; PFAM: FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein YP_004372915.1 InterPro IPR003761; KEGG: apv:Apar_0471 hypothetical protein; PFAM: Exonuclease VII small subunit; SPTR: uncharacterized protein; PFAM: Exonuclease VII small subunit YP_004372916.1 COGs: COG0781 Transcription termination factor; InterPro IPR011605:IPR006027; KEGG: apv:Apar_0470 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: uncharacterized protein; TIGRFAM: transcription antitermination factor NusB; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004372917.1 KEGG: apv:Apar_0469 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004372918.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterProIPR011768:IPR020599:IPR013852:IPR013185:IPR 001059:IPR015365; KEGG: apv:Apar_0468 translation elongation factor P; PFAM: Elongation factor P ; Elongation factor KOW-like domain-containing protein; Elongation factor P/YeiP protein; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004372919.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR001131:IPR000587:IPR000994; KEGG: apv:Apar_0463 peptidase M24; PFAM: peptidase M24; creatinase; SPTR: uncharacterized protein; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain YP_004372920.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: apv:Apar_0462 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; SPTR: uncharacterized protein; PFAM: 3-dehydroquinate synthase YP_004372921.1 COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: apv:Apar_0461 shikimate kinase; PFAM: shikimate kinase; PRIAM: Shikimate kinase; SPTR: uncharacterized protein; PFAM: Shikimate kinase YP_004372922.1 COGs: COG2179 hydrolase of the HAD superfamily; InterPro IPR010021:IPR006549:IPR005834; KEGG: apv:Apar_0460 HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 YP_004372923.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: apv:Apar_0459 aminodeoxychorismate lyase; PFAM: aminodeoxychorismate lyase; SPTR: uncharacterized protein; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004372924.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); InterPro IPR005227:IPR006641; KEGG: ccu:Ccur_05110 conserved hypothetical protein TIGR00250; PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; SPTR: Holliday junction resolvase; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004372925.1 COGs: COG0013 Alanyl-tRNA synthetase; InterProIPR002318:IPR018164:IPR012947:IPR003156:IPR 018165; KEGG: apv:Apar_0457 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like; Threonyl/alanyl tRNA synthetase SAD; phosphoesterase DHHA1; SPTR: uncharacterized protein; TIGRFAM: alanyl-tRNA synthetase; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004372926.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: apv:Apar_0456 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20 YP_004372927.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR014322:IPR014284:IPR000943:IPR000792:IPR 007627:IPR007624:IPR007630; KEGG: apv:Apar_0455 RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SMART: LuxR family transcripitonal regulator; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_004372928.1 KEGG: apv:Apar_0454 hypothetical protein; SPTR: uncharacterized protein YP_004372929.1 KEGG: apv:Apar_0453 hypothetical protein; SPTR: uncharacterized protein YP_004372930.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: apv:Apar_0452 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; manually curated; PFAM: MgsA AAA+ ATPase C terminal; Holliday junction DNA helicase ruvB N-terminus YP_004372931.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006674; KEGG: apv:Apar_0451 metal-dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; PFAM: HD domain YP_004372932.1 InterPro IPR000045; KEGG: hmo:HM1_0253 peptidase a24a, prepilin type IV peptidase; PFAM: peptidase A24A prepilin type IV; SPTR: uncharacterized protein; PFAM: Type IV leader peptidase family YP_004372933.1 KEGG: shi:Shel_09860 hypothetical protein; SPTR: uncharacterized protein YP_004372934.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004701:IPR004720; KEGG: efa:EF0020 PTS system, mannose-specific IIAB components; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component; PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component; PTS system, mannose/fructose/sorbose family, IIB component YP_004372935.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: apv:Apar_0465 phosphotransferase system PTS sorbose-specific IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004372936.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR018405:IPR004704; KEGG: smf:Smon_1299 PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID component; TC 4.A.6 YP_004372937.1 COGs: COG4687 conserved hypothetical protein; InterPro IPR010360; KEGG: cbi:CLJ_B3080 hypothetical protein; PFAM: protein of unknown function DUF956; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF956) YP_004372938.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: apv:Apar_0835 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 2 YP_004372939.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR006224:IPR002942:IPR006145; KEGG: apv:Apar_0839 pseudouridine synthase, RluA family; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004372940.1 COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: apv:Apar_0840 lipoprotein signal peptidase; PFAM: peptidase A8 signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: lipoprotein signal peptidase; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004372941.1 COGs: COG0060 Isoleucyl-tRNA synthetase; InterProIPR002301:IPR001412:IPR015905:IPR002300:IPR 013155:IPR010663; KEGG: apv:Apar_0841 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: uncharacterized protein; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase YP_004372942.1 KEGG: ckr:CKR_1779 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function DUF88 YP_004372943.1 COGs: COG0301 Thiamine biosynthesis ATP pyrophosphatase; InterPro IPR003720:IPR004114:IPR020536; KEGG: apv:Apar_0806 thiamine biosynthesis/tRNA modification protein ThiI; PFAM: Thiamine biosynthesis protein-like; THUMP domain-containing protein; SPTR: Probable tRNA sulfurtransferase; TIGRFAM: thiamine biosynthesis/tRNA modification protein ThiI; PFAM: Thiamine biosynthesis protein (ThiI); THUMP domain; TIGRFAM: thiazole biosynthesis/tRNA modification protein ThiI YP_004372944.1 InterPro IPR003716; KEGG: apv:Apar_0807 hypothetical protein; SPTR: DNA-directed RNA polymerase subunit omega; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004372945.1 COGs: COG0194 Guanylate kinase; InterPro IPR017665:IPR020590:IPR008145:IPR008144; KEGG: apv:Apar_0808 guanylate kinase; PFAM: guanylate kinase; PRIAM: Guanylate kinase; SMART: guanylate kinase/L-type calcium channel region; SPTR: uncharacterized protein; TIGRFAM: guanylate kinase; manually curated; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004372946.1 KEGG: apv:Apar_0809 hypothetical protein; SPTR: uncharacterized protein YP_004372947.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR014732:IPR001754; KEGG: apv:Apar_0810 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: uncharacterized protein; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1 YP_004372948.1 COGs: COG2820 Uridine phosphorylase; InterPro IPR000845; KEGG: lrl:LC705_02352 uridine phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: Uridine phosphorylase; PFAM: Phosphorylase superfamily YP_004372949.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: lrl:LC705_02353 MFS superfamily transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Transporter, major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004372950.1 COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR012914; KEGG: lcb:LCABL_25300 sugar diacid utilization regulator; PFAM: purine catabolism PurC domain protein; SPTR: Sugar diacid utilization regulator; PFAM: Purine catabolism regulatory protein-like family YP_004372951.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR005720:IPR012135:IPR001295; KEGG: apv:Apar_0811 dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate oxidase; SPTR: uncharacterized protein; TIGRFAM: dihydroorotate dehydrogenase family protein; manually curated; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004372952.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterProIPR012165:IPR006058:IPR001221:IPR001433:IPR 019480:IPR017927; KEGG: apv:Apar_0812 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: uncharacterized protein; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004372953.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR002195:IPR006680; KEGG: shi:Shel_11860 dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; SPTR: Dihydroorotase; TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type YP_004372954.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR002082:IPR006130:IPR006132:IPR006131; KEGG: shi:Shel_11850 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004372955.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: ccu:Ccur_07870 pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: uncharacterized protein; PFAM: Phosphoribosyl transferase domain YP_004372956.1 InterPro IPR008454; KEGG: lpj:JDM1_0183 cell surface protein precursor; PFAM: Cna B domain protein; SPTR: uncharacterized protein; PFAM: Cna protein B-type domain YP_004372958.1 COGs: COG1134 ABC-type polysaccharide/polyol phosphate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: apv:Apar_0816 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004372959.1 COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease component; InterPro IPR013525:IPR000412; KEGG: apv:Apar_0602 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; PFAM: ABC-2 type transporter YP_004372960.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR012760:IPR000943:IPR009042:IPR 007627:IPR007624:IPR007630; KEGG: apv:Apar_0824 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004372961.1 COGs: COG0358 DNA primase; InterProIPR006295:IPR002694:IPR006154:IPR013264:IPR 006171:IPR019475; KEGG: apv:Apar_0825 DNA primase; PFAM: DNA primase catalytic core domain; TOPRIM domain-containing protein; DNA primase, DnaB-helicase binding domain; SMART: Toprim sub domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; DnaB-helicase binding domain of primase; TIGRFAM: DNA primase, catalytic core YP_004372962.1 COGs: COG0196 FAD synthase; InterPro IPR002606:IPR015864:IPR015865; KEGG: apv:Apar_0826 riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; SPTR: uncharacterized protein; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_004372963.1 COGs: COG0130 Pseudouridine synthase; InterPro IPR014780:IPR002501; KEGG: apv:Apar_0827 tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; SPTR: uncharacterized protein; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004372964.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: apv:Apar_0828 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: uncharacterized protein; PFAM: DHH family; DHHA1 domain YP_004372965.1 COGs: COG0858 Ribosome-binding factor A; InterPro IPR000238:IPR020053; KEGG: apv:Apar_0829 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004372966.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR005225:IPR006847:IPR000795:IPR 004161; KEGG: apv:Apar_0830 translation initiation factor IF-2; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain-containing protein; elongation factor Tu domain 2 protein; SPTR: Translation initiation factor IF-2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004372967.1 COGs: COG0195 Transcription elongation factor; InterPro IPR010213:IPR013735:IPR004088:IPR003029; KEGG: apv:Apar_0831 NusA antitermination factor; PFAM: NusA domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; TIGRFAM: transcription termination factor NusA YP_004372968.1 InterPro IPR020790:IPR003728; KEGG: ele:Elen_1813 protein of unknown function DUF150; PFAM: protein of unknown function DUF150; SPTR: Ribosome maturation factor rimP; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004372969.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR001412:IPR002300:IPR013155; KEGG: apv:Apar_0833 leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: uncharacterized protein; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004372970.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR018529:IPR015875:IPR000644:IPR001093:IPR 001995; KEGG: apv:Apar_0834 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: uncharacterized protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004372971.1 COGs: COG3589 conserved hypothetical protein; InterPro IPR008589; KEGG: btb:BMB171_C0692 outer surface protein; PFAM: protein of unknown function DUF871; SPTR: Uncharacterized conserved protein; PFAM: Bacterial protein of unknown function (DUF871) YP_004372972.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR004780:IPR000897:IPR003593:IPR013822:IPR 004125; KEGG: apv:Apar_0849 signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; Signal peptide binding (SRP54) M- domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: signal recognition particle protein; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein YP_004372973.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR004390:IPR003593:IPR013822:IPR000897; KEGG: apv:Apar_0850 signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004372974.1 COGs: COG1196 Chromosome segregation ATPase; InterPro IPR011890:IPR003395; KEGG: apv:Apar_0851 chromosome segregation protein SMC; PFAM: SMC domain protein; SPTR: uncharacterized protein; TIGRFAM: chromosome segregation protein SMC; PFAM: RecF/RecN/SMC N terminal domain; SMC proteins Flexible Hinge Domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type YP_004372975.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR011907:IPR000999:IPR001159; KEGG: apv:Apar_0852 ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; PRIAM: Ribonuclease III; SMART: ribonuclease III; double-stranded RNA binding domain protein; SPTR: uncharacterized protein; TIGRFAM: ribonuclease III; PFAM: RNase3 domain; Double-stranded RNA binding motif; TIGRFAM: ribonuclease III, bacterial YP_004372976.1 InterPro IPR003231:IPR006163:IPR009081; KEGG: clj:CLJU_c12820 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: Acyl carrier protein; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004372977.1 COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; InterPro IPR012281:IPR003664; KEGG: apv:Apar_0854 fatty acid/phospholipid synthesis protein PlsX; PFAM: fatty acid synthesis plsX protein; SPTR: uncharacterized protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX; PFAM: Fatty acid synthesis protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX YP_004372978.1 InterPro IPR002677; KEGG: apv:Apar_0855 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004372979.1 InterPro IPR003772; KEGG: apv:Apar_0856 protein of unknown function DUF177; PFAM: protein of unknown function DUF177; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1399 YP_004372980.1 KEGG: apv:Apar_0857 hypothetical protein; SPTR: uncharacterized protein YP_004372981.1 COGs: COG0669 Phosphopantetheine adenylyltransferase; InterPro IPR004821:IPR001980:IPR004820; KEGG: apv:Apar_0858 pantetheine-phosphate adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004372982.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052; KEGG: apv:Apar_0859 methyltransferase; PFAM: Conserved hypothetical protein CHP00095; SPTR: uncharacterized protein; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004372983.1 COGs: COG1200 RecG-like helicase; InterProIPR014001:IPR001650:IPR004365:IPR011545:IPR 014021; KEGG: apv:Apar_0860 helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; OB-fold nucleic acid binding domain; TIGRFAM: ATP-dependent DNA helicase RecG YP_004372984.1 COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR019986:IPR004007; KEGG: apv:Apar_0861 Dak phosphatase; PFAM: Dak phosphatase; SPTR: uncharacterized protein; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV YP_004372985.1 InterPro IPR005531; KEGG: apv:Apar_0862 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF322) YP_004372986.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: ele:Elen_1267 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372987.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR001140:IPR003439:IPR 017940; KEGG: eel:EUBELI_20075 ATP-binding cassette subfamily B protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004372988.1 InterPro IPR001383; KEGG: shi:Shel_09970 LSU ribosomal protein L28P; PFAM: ribosomal protein L28; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein L28; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004372989.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterProIPR012079:IPR000408:IPR018211:IPR015590:IPR 001670; KEGG: eel:EUBELI_02054 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase; SPTR: uncharacterized protein; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase YP_004372990.1 InterPro IPR002575; KEGG: apv:Apar_0390 aminoglycoside phosphotransferase; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein; PFAM: Phosphotransferase enzyme family YP_004372991.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR006282:IPR007371; KEGG: apv:Apar_0864 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase YP_004372992.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; InterProIPR006407:IPR006589:IPR004193:IPR006047:IPR 006048; KEGG: apv:Apar_1051 1,4-alpha-glucan branching enzyme; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; alpha amylase all-beta; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; TIGRFAM: 1,4-alpha-glucan branching enzyme; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004372993.1 COGs: COG0058 Glucan phosphorylase; InterPro IPR011833:IPR000811; KEGG: apv:Apar_1050 glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; SPTR: Phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: Carbohydrate phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases YP_004372994.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR005835:IPR001451; KEGG: apv:Apar_1049 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: Glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004372995.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011832; KEGG: apv:Apar_1048 glucose-1-phosphate adenylyltransferase, GlgD subunit; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: uncharacterized protein; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit YP_004372996.1 COGs: COG0297 Glycogen synthase; InterPro IPR011835:IPR013534:IPR001296; KEGG: apv:Apar_1047 glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain-containing protein; glycosyl transferase group 1; PRIAM: Starch synthase; SPTR: uncharacterized protein; TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004372997.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385:IPR006589:IPR006047; KEGG: apv:Apar_1046 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; TIGRFAM: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; Alpha amylase, catalytic domain; TIGRFAM: 4-alpha-glucanotransferase YP_004372998.1 COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: bcv:Bcav_0902 FmdB family transcripitonal regulator; PFAM: regulatory protein FmdB; SPTR: uncharacterized protein; TIGRFAM: FmdB family transcripitonal regulator; manually curated; PFAM: Zinc ribbon domain; TIGRFAM: FmdB family transcripitonal regulator YP_004372999.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR006027:IPR001678; KEGG: apv:Apar_0866 NusB/RsmB/TIM44; PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; SPTR: uncharacterized protein; PFAM: NOL1/NOP2/sun family; NusB family YP_004373000.1 COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR005794:IPR002376:IPR005793; KEGG: apv:Apar_0867 methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004373001.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: apv:Apar_0868 peptide deformylase; PFAM: formylmethionine deformylase; SPTR: Peptide deformylase; TIGRFAM: peptide deformylase; PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_004373002.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterProIPR005259:IPR014001:IPR001650:IPR011545:IPR 014021; KEGG: apv:Apar_0869 primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: primosomal protein N'; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N' YP_004373003.1 COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: apv:Apar_0501 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004373004.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR004527:IPR001412:IPR020060:IPR020058; KEGG: apv:Apar_0504 glutamyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: uncharacterized protein; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004373005.1 COGs: COG1760 L-serine deaminase; InterProIPR004643:IPR004642:IPR005131:IPR002912:IPR 005130; KEGG: apv:Apar_0503 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; amino acid-binding ACT domain protein; PRIAM: L-serine ammonia-lyase; SPTR: uncharacterized protein; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: ACT domain; Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; L-serine dehydratase, iron-sulfur-dependent, alpha subunit YP_004373006.1 InterPro IPR005490; KEGG: ele:Elen_1958 ErfK/YbiS/YcfS/YnhG family protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; SPTR: uncharacterized protein; PFAM: peptidoglycan binding domain; L,D-transpeptidase catalytic domain YP_004373007.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ele:Elen_1538 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004373008.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: ele:Elen_1537 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004373009.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: ele:Elen_1535 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004373010.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143:IPR000089; KEGG: bll:BLJ_0769 RND family efflux transporter; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004373011.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: ele:Elen_1024 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004373012.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: bll:BLJ_0771 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004373013.1 COGs: COG1073 Hydrolase of the alpha/beta superfamily; KEGG: bcy:Bcer98_0257 alpha/beta hydrolase; SPTR: uncharacterized protein YP_004373014.1 COGs: COG0392 integral membrane protein; InterPro IPR005242; KEGG: apv:Apar_0911 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004373015.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ere:EUBREC_2585 NAGC-like transcriptional regulator; PFAM: ROK family protein; SPTR: NAGC-like transcriptional regulator; PFAM: ROK family YP_004373016.1 COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: bmq:BMQ_3646 glycosyl hydrolase, family 31; PFAM: glycoside hydrolase family 31; SPTR: Glycosyl hydrolase, family 31; PFAM: Glycosyl hydrolases family 31 YP_004373017.1 COGs: COG0176 Transaldolase; InterPro IPR001585; KEGG: bmq:BMQ_3648 transaldolase; PFAM: Transaldolase; SPTR: transaldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family YP_004373018.1 KEGG: ere:EUBREC_2594 hypothetical protein; SPTR: uncharacterized protein YP_004373019.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: bmq:BMQ_3645 hypothetical protein; SPTR: uncharacterized protein; PFAM: L-fucose isomerase, C-terminal domain YP_004373020.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002204:IPR006115; KEGG: bpo:BP951000_1132 3-hydroxyisobutyrate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 3-hydroxyisobutyrate dehydrogenase; SPTR: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase YP_004373021.1 InterPro IPR002781; KEGG: ere:EUBREC_2591 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE YP_004373022.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR001927:IPR018043; KEGG: bmq:BMQ_3649 sugar transporter; SPTR: Sugar transporter; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter YP_004373023.1 KEGG: dma:DMR_35750 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004373024.1 COGs: COG3572 Gamma-glutamylcysteine synthetase; InterPro IPR006336; KEGG: ele:Elen_2348 glutamate--cysteine ligase; PFAM: glutamate--cysteine ligase GCS2; SPTR: Glutamate--cysteine ligase; PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: glutamate--cysteine ligase, plant type YP_004373026.1 InterPro IPR008160; KEGG: bfs:BF3553 hypothetical protein; PFAM: Collagen triple helix repeat-containing protein; SPTR: uncharacterized protein; PFAM: Collagen triple helix repeat (20 copies) YP_004373027.1 KEGG: amt:Amet_3803 copper amine oxidase domain-containing protein; SPTR: Copper amine oxidase domain protein YP_004373028.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR006675:IPR003607:IPR002646:IPR006674; KEGG: apv:Apar_0497 metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG YP_004373029.1 COGs: COG3579 Aminopeptidase C; InterPro IPR004134:IPR000169; KEGG: apv:Apar_0899 bleomycin hydrolase; PFAM: peptidase C1B bleomycin hydrolase; PRIAM: Bleomycin hydrolase; SPTR: uncharacterized protein; PFAM: Peptidase C1-like family YP_004373030.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR017583:IPR011611; KEGG: str:Sterm_1965 1-phosphofructokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family YP_004373031.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterProIPR006318:IPR018274:IPR008731:IPR008279:IPR 000121; KEGG: apv:Apar_0600 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; SPTR: uncharacterized protein; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_004373032.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698:IPR000032; KEGG: shi:Shel_13270 phosphotransferase system HPr (HPr) family protein; PFAM: phosphoryl transfer system HPr; SPTR: uncharacterized protein; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004373033.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR003353:IPR006327:IPR004715:IPR003352:IPR 002178:IPR013011:IPR013014; KEGG: apv:Apar_0321 PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; SPTR: uncharacterized protein; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; TC 4.A.2.1.8 YP_004373034.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ele:Elen_0843 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2 YP_004373035.1 KEGG: bde:BDP_2053 dTDP-rhamnosyl transferase RfbF; SPTR: uncharacterized protein YP_004373036.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ele:Elen_2052 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2 YP_004373037.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR000888:IPR005913; KEGG: blj:BLD_1569 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase., dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose reductase YP_004373038.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR005888:IPR001509; KEGG: blo:BL0229 dTDP-glucose 4,6-dehydratase enzyme involved in rhamnose biosynthesis; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004373039.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005907:IPR005835; KEGG: ele:Elen_2049 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_004373040.1 KEGG: ele:Elen_2047 hypothetical protein; SPTR: uncharacterized protein YP_004373041.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: ele:Elen_2042 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2 YP_004373042.1 COGs: COG4713 membrane protein; InterPro IPR018674; KEGG: cac:CA_C0024 hypothetical protein; PFAM: Protein of unknown function DUF2142, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2142) YP_004373043.1 COGs: COG3757 Lyzozyme M1 (1 4-beta-N-acetylmuramidase); InterPro IPR006203:IPR002053; KEGG: ccu:Ccur_08300 glycosyl hydrolase family 25; PFAM: glycoside hydrolase family 25; SPTR: Glycosyl hydrolase family 25; PFAM: Glycosyl hydrolases family 25 YP_004373044.1 InterPro IPR002797; KEGG: ahe:Arch_0085 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: uncharacterized protein; PFAM: Polysaccharide biosynthesis protein YP_004373045.1 KEGG: ptm:GSPATT00003142001 hypothetical protein; SPTR: rhamnosyltransferase YP_004373046.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: san:gbs1480 glycosyl transferase, group 1 family protein; PFAM: glycosyl transferase group 1; SPTR: Glycosyltransferase; manually curated; PFAM: Glycosyl transferases group 1 YP_004373047.1 KEGG: pti:PHATRDRAFT_20318 hypothetical protein; SPTR: Phosphatase 1 regulatory subunit YP_004373048.1 KEGG: ele:Elen_2055 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2304) YP_004373049.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ele:Elen_2054 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 2 YP_004373050.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: ele:Elen_2037 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: Glycosyl transferase family 2; PFAM: Glycosyl transferase family 2 YP_004373051.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR017900:IPR004108:IPR017896; KEGG: apv:Apar_0411 ferredoxin hydrogenase; PFAM: hydrogenase large subunit domain protein; SPTR: Ferredoxin hydrogenase; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain YP_004373052.1 KEGG: gdj:Gdia_1899 phosphoenolpyruvate-protein phosphotransferase YP_004373053.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: ele:Elen_2269 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004373054.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003439; KEGG: ele:Elen_2270 FeS assembly ATPase SufC; PFAM: ABC transporter related; SPTR: uncharacterized protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004373055.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231:IPR000825; KEGG: ele:Elen_2271 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: uncharacterized protein; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_004373056.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: ele:Elen_2272 SufBD protein; PFAM: SufBD protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family (UPF0051) YP_004373057.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR010970:IPR000192; KEGG: ele:Elen_2273 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: uncharacterized protein; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily YP_004373058.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: shi:Shel_26820 SUF system FeS assembly protein, NifU family; PFAM: nitrogen-fixing NifU domain protein; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family YP_004373059.1 KEGG: cno:NT01CX_0217 hypothetical protein; SPTR: uncharacterized protein YP_004373060.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; KEGG: cac:CA_C2565 NifU-like domain-containing protein; SPTR: uncharacterized protein YP_004373061.1 KEGG: dhd:Dhaf_4454 VanZ family protein; SPTR: uncharacterized protein; PFAM: VanZ like family YP_004373062.1 KEGG: sdn:Sden_1485 ATPase; SPTR: uncharacterized protein YP_004373063.1 COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347:IPR002198; KEGG: mkm:Mkms_4161 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase YP_004373064.1 COGs: COG1158 Transcription termination factor; InterProIPR004665:IPR011129:IPR003593:IPR011112:IPR 011113:IPR000194; KEGG: apv:Apar_0531 transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; Rho termination factor RNA-binding; Rho termination factor domain protein; SMART: AAA ATPase; Cold shock protein; SPTR: uncharacterized protein; TIGRFAM: transcription termination factor Rho; PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho YP_004373065.1 COGs: COG0018 Arginyl-tRNA synthetase; InterPro IPR001278:IPR015945:IPR005148:IPR008909; KEGG: apv:Apar_0529 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004373066.1 KEGG: apv:Apar_1018 hypothetical protein; SPTR: uncharacterized protein; PFAM: CarD-like/TRCF domain YP_004373067.1 COGs: COG2077 Peroxiredoxin; InterPro IPR013740:IPR017936; KEGG: llm:llmg_0318 thiol peroxidase; PFAM: Redoxin domain protein; SPTR: Thiol peroxidase; PFAM: Redoxin YP_004373068.1 COGs: COG3247 conserved hypothetical protein; KEGG: ste:STER_0464 hypothetical protein; SPTR: uncharacterized protein YP_004373069.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: apv:Apar_0518 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004373070.1 KEGG: apv:Apar_0877 hypothetical protein; SPTR: uncharacterized protein YP_004373071.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: apv:Apar_0878 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: uncharacterized protein; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004373072.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: apv:Apar_0879 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, COG1636 YP_004373073.1 KEGG: lsg:lse_0555 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF3267) YP_004373074.1 COGs: COG0143 Methionyl-tRNA synthetase; InterPro IPR015413; KEGG: apv:Apar_0881 methionine--tRNA ligase; PFAM: tRNA synthetase class I (M); PRIAM: Methionine--tRNA ligase; SPTR: uncharacterized protein; PFAM: tRNA synthetases class I (M) YP_004373075.1 InterPro IPR000182; KEGG: ele:Elen_1425 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004373076.1 COGs: COG0661 unusual protein kinase; InterPro IPR004147; KEGG: bll:BLJ_0228 ATP-binding domain-containing protein; PFAM: ABC-1 domain-containing protein; SPTR: uncharacterized protein; PFAM: ABC1 family YP_004373077.1 KEGG: nda:Ndas_3684 transcriptional regulator, PadR-like family; SPTR: uncharacterized protein YP_004373078.1 COGs: COG1278 Cold shock protein; InterPro IPR012156:IPR011129:IPR002059; KEGG: aau:AAur_1000 cold shock protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: cold shock protein; PFAM: 'Cold-shock' DNA-binding domain YP_004373079.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR000672:IPR020630:IPR020631; KEGG: afw:Anae109_2520 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004373080.1 COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR020628:IPR000559; KEGG: ele:Elen_2864 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; PFAM: Formate--tetrahydrofolate ligase YP_004373081.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; InterProIPR008823:IPR004605:IPR003593:IPR008824:IPR 003959; KEGG: apv:Apar_0893 Holliday junction DNA helicase RuvB; PFAM: AAA ATPase central domain protein; Holliday junction DNA helicase RuvB domain; SMART: AAA ATPase; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004373082.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR000085:IPR013849:IPR011114; KEGG: apv:Apar_0894 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; RuvA domain protein; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004373083.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176; KEGG: apv:Apar_0895 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004373084.1 KEGG: sma:SAV_5948 NH(3)-dependent NAD(+) synthetase; SPTR: uncharacterized protein; PFAM: NAD synthase YP_004373085.1 COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: cac:CA_C2450 desulfoferrodoxin; PFAM: Desulfoferrodoxin ferrous iron-binding region; SPTR: uncharacterized protein; PFAM: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain YP_004373086.1 KEGG: syf:Synpcc7942_2119 RNA methyltransferase TrmH, group 3; SPTR: uncharacterized protein YP_004373087.1 COGs: COG4989 oxidoreductase; InterPro IPR001395; KEGG: lrl:LC705_02399 aldo/keto reductase family oxidoreductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family YP_004373088.1 KEGG: cfl:Cfla_0273 membrane protein-like protein; SPTR: Membrane protein-like protein YP_004373089.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: sth:STH954 beta-glucosidase; PFAM: glycoside hydrolase family 1; SPTR: Beta-glucosidase; PFAM: Glycosyl hydrolase family 1 YP_004373090.1 COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: lin:lin0917 hypothetical protein; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: PTS system, beta-glucoside-specific, IIA component; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit YP_004373091.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR003352:IPR004501; KEGG: lmy:LM5923_0950 hypothetical protein; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, IIC component; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373092.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR003501:IPR013012; KEGG: lmc:Lm4b_00934 PTS system, IIB component; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system, cellobiose-specific IIB component; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373093.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterProIPR005698:IPR001020:IPR002114:IPR018228:IPR 000032; KEGG: sth:STH955 PTS system phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004373094.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178; KEGG: cdl:CDR20291_2922 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373096.1 COGs: COG3414 Phosphotransferase system galactitol-specific IIB component; InterPro IPR003501:IPR013011; KEGG: apv:Apar_0151 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373097.1 KEGG: ace:Acel_1486 hypothetical protein; SPTR: uncharacterized protein YP_004373098.1 COGs: COG3944 Capsular polysaccharide biosynthesis protein; InterPro IPR005702:IPR003856; KEGG: cms:CMS_2399 surface polysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: uncharacterized protein; TIGRFAM: capsular exopolysaccharide family; PFAM: Chain length determinant protein; TIGRFAM: capsular exopolysaccharide family YP_004373099.1 InterPro IPR001387; KEGG: ele:Elen_1959 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; manually curated; PFAM: Helix-turn-helix YP_004373101.1 InterPro IPR001387; KEGG: ele:Elen_1959 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; manually curated; PFAM: Helix-turn-helix YP_004373102.1 COGs: COG3394 conserved hypothetical protein; InterPro IPR006879; KEGG: bcl:ABC2079 hypothetical protein; PFAM: YdjC family protein; SPTR: uncharacterized protein; PFAM: YdjC-like protein YP_004373103.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: str:Sterm_4107 glycoside hydrolase family 4; PFAM: glycoside hydrolase family 4; SPTR: uncharacterized protein; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004373104.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611; KEGG: pap:PSPA7_3342 ribokinase; PFAM: PfkB domain protein; SPTR: Possible ribokinase; PFAM: pfkB family carbohydrate kinase YP_004373105.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: lmy:LM5923_0073 hypothetical protein; PFAM: ADP-ribosylation/Crystallin J1; SPTR: BvrC; PFAM: ADP-ribosylglycohydrolase YP_004373106.1 InterPro IPR011701; KEGG: clj:CLJU_c24980 transporter protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004373107.1 InterPro IPR007525; KEGG: amt:Amet_0212 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: uncharacterized protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus YP_004373108.1 KEGG: bca:BCE_5386 polysaccharide transport protein, SPTR: uncharacterized protein YP_004373109.1 KEGG: amt:Amet_0211 hypothetical protein; SPTR: WfaX; PFAM: Polysaccharide pyruvyl transferase YP_004373110.1 KEGG: bcz:BCZK0795 hypothetical protein; SPTR: Predicted protein YP_004373111.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: nmu:Nmul_A0170 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: Glycosyl transferase, group 1; PFAM: Glycosyl transferases group 1 YP_004373112.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: cpe:CPE0496 N-acetyl-mannosamine transferase; PFAM: glycosyl transferase WecB/TagA/CpsF; SPTR: EpsP; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family YP_004373113.1 COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR013096; KEGG: pdi:BDI_3226 mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Cupin 2 conserved barrel domain protein; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-6-phosphate isomerase mannose-1-phosphate guanylyl transferase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase YP_004373114.1 COGs: COG1109 Phosphomannomutase; InterPro IPR016066:IPR005844:IPR005845; KEGG: shi:Shel_23220 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004373115.1 KEGG: bad:BAD_1390 hypothetical protein; SPTR: uncharacterized protein YP_004373116.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: ele:Elen_2444 undecaprenyl-phosphate galactose phosphotransferase; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactose phosphotransferase; PFAM: Bacterial sugar transferase YP_004373117.1 COGs: COG0250 Transcription antiterminator; InterPro IPR005824:IPR006645; KEGG: ele:Elen_1880 NusG antitermination factor; PFAM: NGN domain-containing protein; SMART: KOW domain protein; SPTR: uncharacterized protein; PFAM: Transcription termination factor nusG; KOW motif YP_004373118.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR018247:IPR003141:IPR004013:IPR 011708:IPR004365; KEGG: apv:Apar_0898 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004373119.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933; KEGG: ele:Elen_0135 dipeptidase; PFAM: peptidase M20; SPTR: uncharacterized protein; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; TIGRFAM: dipeptidase YP_004373120.1 COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: sss:SSUSC84_1353 5'-nucleotidase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_004373121.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR000110:IPR003029; KEGG: apv:Apar_0962 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: uncharacterized protein; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004373122.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834; KEGG: dau:Daud_0172 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase YP_004373123.1 COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: ele:Elen_1252 nucleoside-diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase YP_004373124.1 COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR020557:IPR003031:IPR000362; KEGG: ele:Elen_2338 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: uncharacterized protein; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004373125.1 InterPro IPR002528; KEGG: cbe:Cbei_3145 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; PFAM: MatE YP_004373126.1 InterPro IPR013216; KEGG: ctc:CTC02188 methyltransferase, 3-demethylubiquinone-9 3-methyltransferase; PFAM: Methyltransferase type 11; SPTR: uncharacterized protein; PFAM: Methyltransferase domain YP_004373127.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR002421:IPR008918:IPR001098:IPR 002298:IPR020046:IPR020047; KEGG: apv:Apar_1104 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; DNA-directed DNA polymerase; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I YP_004373128.1 COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: ele:Elen_0400 peptidase M18 aminopeptidase I; PFAM: peptidase M18 aminopeptidase I; SPTR: M18 family aminopeptidase; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004373129.1 COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR017871:IPR003593:IPR003439:IPR013611; KEGG: apv:Apar_0607 ABC transporter related; PFAM: ABC transporter related; Transport-associated OB domain-containing protein; SMART: AAA ATPase; SPTR: Glycerol-3-phosphate-transporting ATPase; PFAM: ABC transporter; TOBE domain YP_004373130.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: ere:EUBREC_1840 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase YP_004373131.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ere:EUBREC_0249 catabolite control protein A; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373132.1 COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: bde:BDP_2204 permease protein of ABC transporter system for sugars; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 2, CUT1 family TC 3.A.1.1.-); PFAM: Binding-protein-dependent transport system inner membrane component YP_004373133.1 COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: bln:Blon_2442 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004373134.1 COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006311:IPR006059:IPR017909; KEGG: apv:Apar_0604 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: ABC superfamily ATP binding cassette transporter solute-binding protein YP_004373135.1 InterPro IPR002931; KEGG: cpy:Cphy_2186 transglutaminase domain-containing protein; PFAM: transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein; SPTR: Transglutaminase-like superfamily; PFAM: Transglutaminase-like superfamily YP_004373136.1 COGs: COG3669 Alpha-L-fucosidase; InterPro IPR016286:IPR000933; KEGG: cpy:Cphy_2190 alpha-L-fucosidase; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase YP_004373137.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR006311:IPR000914:IPR017909; KEGG: clo:HMPREF0868_1083 bacterial extracellular solute-binding protein, family 5; PFAM: extracellular solute-binding protein family 5; SPTR: Extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004373138.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: clo:HMPREF0868_1082 glutathione ABC transporter, permease protein GsiC; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Glutathione ABC transporter, permease protein GsiC; PFAM: Binding-protein-dependent transport system inner membrane component YP_004373139.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: clo:HMPREF0868_1081 ABC transporter, permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport system inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component YP_004373140.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR010066:IPR017871:IPR003593:IPR003439:IPR 013563; KEGG: clo:HMPREF0868_1080 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Glutathione import ATP-binding protein GsiA; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004373141.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR010066:IPR017871:IPR003593:IPR003439:IPR 013563; KEGG: clo:HMPREF0868_1079 ABC transporter, ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004373142.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: ele:Elen_2064 thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004373143.1 COGs: COG2145 Hydroxyethylthiazole kinase sugar kinase family; InterPro IPR011144:IPR000417; KEGG: ele:Elen_2063 hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase; PRIAM: Hydroxyethylthiazole kinase; SPTR: Hydroxyethylthiazole kinase; PFAM: Hydroxyethylthiazole kinase family; TIGRFAM: hydroxyethylthiazole kinase YP_004373144.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: ele:Elen_2062 thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; SPTR: Thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004373145.1 COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: ele:Elen_2061 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: uncharacterized protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004373146.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: sea:SeAg_B4593 oxidoreductase, zinc-binding dehydrogenase family; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004373147.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: cdl:CDR20291_0435 PTS system, IIb component; PFAM: PTS system sorbose subfamily IIB component; SPTR: uncharacterized protein; PFAM: PTS system sorbose subfamily IIB component YP_004373148.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: tau:Tola_1978 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004373149.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: lrh:LGG_00417 PTS system mannose-specific transporter subunit IICD; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component YP_004373150.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: lcz:LCAZH_2766 PTS system mannose-specific transporter subunit IICD; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004373151.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: cdf:CD0284 PTS system, IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004373152.1 InterPro IPR001387; KEGG: shi:Shel_15940 predicted transcriptional regulator; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004373153.1 InterPro IPR001387; KEGG: shi:Shel_15940 predicted transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Predicted transcriptional regulator; PFAM: Helix-turn-helix YP_004373154.1 COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650:IPR017439; KEGG: amt:Amet_2941 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: uncharacterized protein; TIGRFAM: amidohydrolase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004373155.1 COGs: COG1671 conserved hypothetical protein; InterPro IPR003791; KEGG: ele:Elen_1794 protein of unknown function DUF188; PFAM: protein of unknown function DUF188; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YaiI/YqxD family COG1671 YP_004373156.1 InterPro IPR001455:IPR019870; KEGG: ere:EUBREC_3158 hypothetical protein; PFAM: SirA-like domain-containing protein; SPTR: Selenium metabolism protein YedF; TIGRFAM: selenium metabolism protein YedF; PFAM: DsrE/DsrF-like family; SirA-like protein; TIGRFAM: selenium metabolism protein YedF YP_004373157.1 KEGG: ele:Elen_1282 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function, DUF488 YP_004373158.1 InterPro IPR002645:IPR003594; KEGG: apv:Apar_0915 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; ATP-binding region ATPase domain protein; SPTR: Anti-sigma factor antagonist; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; STAS domain; TIGRFAM: anti-anti-sigma factor YP_004373159.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: ccu:Ccur_11850 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004373160.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003018:IPR010822:IPR001932; KEGG: apv:Apar_0916 PAS/PAC sensor protein; PFAM: Stage II sporulation protein E; GAF domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; SPTR: uncharacterized protein; PFAM: GAF domain; Stage II sporulation protein E (SpoIIE) YP_004373161.1 COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR006311:IPR017909:IPR000914; KEGG: stp:Strop_3796 4-phytase; PFAM: extracellular solute-binding protein family 5; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_004373162.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterProIPR017871:IPR010066:IPR003439:IPR013563:IPR 003593; KEGG: bbt:BBta_6951 oligopeptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004373163.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR017871:IPR010066:IPR003439:IPR013563:IPR 003593; KEGG: chl:Chy400_2434 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004373164.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: chy:CHY_1130 oligopeptide/dipeptide ABC transporter, permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004373165.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: chy:CHY_1129 oligopeptide/dipeptide ABC transporter, permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component YP_004373166.1 COGs: COG4166 ABC-type oligopeptide transport system periplasmic component; InterPro IPR006311:IPR017909:IPR000914; KEGG: cbe:Cbei_4928 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Dipeptide ABC superfamily ATP binding cassette transporter, binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004373167.1 InterPro IPR004692; KEGG: shi:Shel_10170 protein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004373168.1 COGs: COG0696 Phosphoglyceromutase; InterPro IPR005995:IPR011258:IPR006124; KEGG: ele:Elen_1776 phosphoglyceromutase; PFAM: BPG-independent PGAM domain protein; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase YP_004373169.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR017441:IPR020861:IPR000652; KEGG: apv:Apar_0922 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004373170.1 COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911:IPR001576; KEGG: apv:Apar_0923 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase YP_004373171.1 COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020830:IPR020832:IPR006424:IPR020828:IPR 020829:IPR020831; KEGG: cbt:CLH_2814 glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Glyceraldehyde-3-phosphate dehydrogenase (Phosphorylating); TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004373172.1 COGs: COG1481 conserved hypothetical protein; InterPro IPR003802:IPR018478; KEGG: ele:Elen_1781 protein of unknown function DUF199; PFAM: protein of unknown function DUF199; Sporulation regulator WhiA-like; SPTR: uncharacterized protein; PFAM: Sporulation Regulator WhiA N terminal; Sporulation Regulator WhiA C terminal domain; TIGRFAM: conserved hypothetical protein YP_004373173.1 COGs: COG0391 conserved hypothetical protein; InterPro IPR010119:IPR002882; KEGG: ccu:Ccur_07110 conserved hypothetical protein, CofD-related; PFAM: protein of unknown function UPF0052 and CofD; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_004373174.1 COGs: COG1660 P-loop-containing kinase; InterPro IPR005337; KEGG: apv:Apar_0926 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein COLAER_02220; PFAM: P-loop ATPase protein family YP_004373175.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cpy:Cphy_0299 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: Glycosyl transferase family 2 YP_004373176.1 KEGG: cth:Cthe_1207 membrane protein-like protein; SPTR: uncharacterized protein YP_004373177.1 KEGG: bde:BDP_1612 CTP synthase (UTP-ammonia lyase); SPTR: uncharacterized protein YP_004373178.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR004791:IPR001943:IPR000305:IPR001162; KEGG: apv:Apar_0938 excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; Excinuclease ABC C subunit domain protein; UvrB/UvrC protein; SMART: Excinuclease ABC C subunit domain protein; SPTR: uncharacterized protein; TIGRFAM: excinuclease ABC, C subunit; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004373179.1 COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: ele:Elen_2117 virulence factor MviN family protein; PFAM: virulence factor MVIN family protein; SPTR: uncharacterized protein; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_004373180.1 KEGG: dvi:Dvir_GJ21426 GJ21426 gene product from transcript GJ21426-RA; SPTR: GJ21426 YP_004373181.1 KEGG: cfa:608873 hypothetical protein LOC608873; SPTR: uncharacterized protein YP_004373182.1 KEGG: fps:FP0168 cell surface leucine-rich repeat-containing protein; SPTR: Probable cell surface protein (Leucine-rich repeat protein) YP_004373183.1 KEGG: aba:Acid345_4385 hypothetical protein YP_004373184.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR017871:IPR004602:IPR003439; KEGG: apv:Apar_0941 excinuclease ABC, A subunit; PFAM: ABC transporter related; SPTR: uncharacterized protein; TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004373185.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: apv:Apar_0943 ATP-binding protein; PFAM: ATPase-like, ParA/MinD; SPTR: uncharacterized protein; PFAM: ParA/MinD ATPase like YP_004373186.1 COGs: COG2081 flavoprotein; InterPro IPR004792; KEGG: ele:Elen_1017 HI0933 family protein; PFAM: HI0933 family protein; SPTR: uncharacterized protein; PFAM: HI0933-like protein YP_004373187.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076; KEGG: ele:Elen_1018 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: uncharacterized protein; PFAM: FAD binding domain YP_004373188.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: cbt:CLH_3242 NADPH-dependent butanol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004373189.1 COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: hor:Hore_09610 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: uncharacterized protein; PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_004373190.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: lwe:lwe0350 phosphoglycerate dehydrogenase family protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004373191.1 COGs: COG3775 Phosphotransferase system galactitol-specific IIC component; InterPro IPR004703; KEGG: str:Sterm_3552 PTS system galactitol-specific IIC component; PFAM: PTS system Galactitol-specific IIC component; SPTR: uncharacterized protein; PFAM: PTS system sugar-specific permease component; TC 4.A.5 YP_004373192.1 InterPro IPR003501; KEGG: lwe:lwe0348 PTS system, galactitol-specific IIB component, PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Complete genome; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TC 4.A.5 YP_004373193.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: tit:Thit_0498 PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: uncharacterized protein; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373194.1 KEGG: sfr:Sfri_1648 phage repressor; SPTR: uncharacterized protein YP_004373195.1 KEGG: tjr:TherJR_0669 helix-turn-helix domain protein; SPTR: uncharacterized protein YP_004373196.1 InterPro IPR001387; KEGG: dap:Dacet_0546 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004373197.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: bcl:ABC4074 hypothetical protein; PFAM: sugar isomerase (SIS); SPTR: Sugar isomerase; PFAM: SIS domain YP_004373198.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: bcl:ABC4073 PTS system, mannose-specific enzyme II, D component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: D component PTS system mannose-specific enzyme II; PFAM: PTS system mannose/fructose/sorbose family IID component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IID component; TC 4.A.6 YP_004373199.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: cbe:Cbei_0965 phosphotransferase system PTS, sorbose-specific IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system sorbose-specific iic component YP_004373200.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: bcl:ABC4071 PTS system, mannose-specific enzyme II, B component; PFAM: PTS system sorbose subfamily IIB component; SPTR: PTS system, mannose/fructose/sorbose family,IIB component; PFAM: PTS system sorbose subfamily IIB component YP_004373201.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: kpu:KP1_0760 PTS permease; PFAM: PTS system fructose subfamily IIA component; SPTR: Predicted protein; PFAM: PTS system fructose IIA component YP_004373202.1 KEGG: lrl:LC705_00723 transcriptional regulator; SPTR: uncharacterized protein; manually curated YP_004373203.1 COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR017900:IPR017896:IPR001395; KEGG: rci:RCIX2176 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family YP_004373204.1 COGs: COG0328 Ribonuclease HI; InterPro IPR002156; KEGG: apv:Apar_1103 ribonuclease H; PFAM: ribonuclease H; PRIAM: Ribonuclease H; SPTR: uncharacterized protein; PFAM: RNase H YP_004373205.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: gct:GC56T3_3239 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: uncharacterized protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold YP_004373206.1 COGs: COG1254 Acylphosphatase; InterPro IPR001792; KEGG: hoh:Hoch_6574 acylphosphatase; PFAM: acylphosphatase; SPTR: uncharacterized protein; PFAM: Acylphosphatase YP_004373207.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: ccu:Ccur_01120 Fe2+/Zn2+ uptake regulation protein; PFAM: ferric-uptake regulator; SPTR: uncharacterized protein; PFAM: Ferric uptake regulator family YP_004373208.1 COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002307:IPR002942:IPR002305; KEGG: ele:Elen_0588 tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; SPTR: uncharacterized protein; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004373209.1 KEGG: sli:Slin_2954 hypothetical protein; SPTR: uncharacterized protein YP_004373210.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR011816:IPR001264:IPR001460; KEGG: apv:Apar_1010 penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family YP_004373211.1 COGs: COG1438 Arginine repressor; InterPro IPR001669:IPR020899; KEGG: apv:Apar_1011 arginine repressor, ArgR; PFAM: Arginine repressor-like; SPTR: uncharacterized protein; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004373212.1 COGs: COG3957 Phosphoketolase; InterPro IPR019790:IPR018970:IPR005593:IPR018969; KEGG: apv:Apar_1219 phosphoketolase; PFAM: Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase-like; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; PRIAM: Fructose-6-phosphate phosphoketolase; SPTR: uncharacterized protein; PFAM: XFP N-terminal domain; D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; XFP C-terminal domain YP_004373213.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: apv:Apar_1220 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373214.1 InterPro IPR001173; KEGG: tbd:Tbd_1783 glucosyltransferase protein; PFAM: glycosyl transferase family 2; SPTR: Glycosyltransferase involved in cell wall biogenesis; PFAM: Glycosyl transferase family 2 YP_004373215.1 COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406:IPR020097; KEGG: apv:Apar_1129 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: uncharacterized protein; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004373216.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871:IPR003439:IPR003339:IPR003593; KEGG: bll:BLJ_1432 fused ATP-binding protein and permease of ABC transporter; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; Cobalt transport protein YP_004373217.1 COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: ccu:Ccur_01460 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004373218.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR011260:IPR011773:IPR011261:IPR011262:IPR 011263; KEGG: apv:Apar_1133 DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase insert; RNA polymerase dimerisation; RNA polymerase alpha subunit domain protein; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004373219.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR005709:IPR002942:IPR001912; KEGG: shi:Shel_19720 SSU ribosomal protein S4P; PFAM: RNA-binding S4 domain protein; ribosomal protein S4; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004373220.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR018102:IPR019981:IPR001971; KEGG: apv:Apar_1135 ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004373221.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR018269:IPR019980:IPR001892; KEGG: mta:Moth_2434 30S ribosomal protein S13; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: 30S ribosomal protein S13; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004373222.1 InterPro IPR000473; KEGG: ccu:Ccur_01410 LSU ribosomal protein L36P; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004373223.1 COGs: COG0361 Translation initiation factor 1 (IF-1); InterPro IPR004368:IPR006196; KEGG: apv:Apar_1138 translation initiation factor IF-1; PFAM: S1 IF1 family protein; SPTR: uncharacterized protein; TIGRFAM: translation initiation factor IF-1; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004373224.1 COGs: COG0024 Methionine aminopeptidase; InterPro IPR002467:IPR001714:IPR000994; KEGG: apv:Apar_1139 methionine aminopeptidase, type I; PFAM: peptidase M24; SPTR: Methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: Metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_004373225.1 COGs: COG0563 Adenylate kinase and related kinase; InterPro IPR000850:IPR019777:IPR006259; KEGG: apv:Apar_1140 adenylate kinase; PFAM: adenylate kinase; SPTR: Adenylate kinase; TIGRFAM: adenylate kinase; PFAM: Adenylate kinase; TIGRFAM: adenylate kinases YP_004373226.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR019825:IPR002208; KEGG: apv:Apar_1141 preprotein translocase, SecY subunit; PFAM: SecY protein; SPTR: Preprotein translocase subunit secY; TIGRFAM: preprotein translocase, SecY subunit; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004373227.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR001196:IPR005749; KEGG: apv:Apar_1142 ribosomal protein L15; SPTR: 50S ribosomal protein L15; TIGRFAM: ribosomal protein L15; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004373228.1 COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR005996:IPR000517; KEGG: ele:Elen_2160 ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004373229.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR005712:IPR013810:IPR005324; KEGG: apv:Apar_1144 ribosomal protein S5; PFAM: Ribosomal protein S5 ; ribosomal protein S5 domain protein; SPTR: 30S ribosomal protein S5; TIGRFAM: ribosomal protein S5; PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004373230.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR004389:IPR005484; KEGG: apv:Apar_1145 ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004373231.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR002358:IPR019906:IPR020040:IPR000702; KEGG: apv:Apar_1146 ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004373232.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: ele:Elen_2164 ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: uncharacterized protein; PFAM: Ribosomal protein S8 YP_004373233.1 COGs: COG0199 Ribosomal protein S14; InterPro IPR018271:IPR001209; KEGG: apv:Apar_1148 ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: Ribosomal protein S14; PFAM: Ribosomal protein S14p/S29e YP_004373234.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR020929; KEGG: apv:Apar_1149 ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_004373235.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: dda:Dd703_2426 auxin efflux carrier; PFAM: Auxin Efflux Carrier; SPTR: Auxin Efflux Carrier; PFAM: Membrane transport protein YP_004373236.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR005825:IPR003256:IPR005824; KEGG: shi:Shel_23360 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004373237.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR005745:IPR000218; KEGG: apv:Apar_1151 ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004373238.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR000266:IPR019979:IPR019984; KEGG: apv:Apar_1152 ribosomal protein S17; PFAM: ribosomal protein S17; SPTR: uncharacterized protein; TIGRFAM: 30S ribosomal protein S17; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004373239.1 InterPro IPR018254:IPR001854; KEGG: apv:Apar_1153 ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein L29; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004373240.1 COGs: COG0197 Ribosomal protein L16/L10E; InterPro IPR020798:IPR000114:IPR016180; KEGG: apv:Apar_1154 ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: ribosomal protein L16; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004373241.1 COGs: COG0092 Ribosomal protein S3; InterProIPR018280:IPR005704:IPR004044:IPR008282:IPR 001351:IPR004087; KEGG: apv:Apar_1155 ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; Ribosomal protein S3 domain; KH type 2 domain protein; SMART: KH domain protein; SPTR: 30S ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004373242.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR018260:IPR005727:IPR001063; KEGG: apv:Apar_1156 ribosomal protein L22; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004373243.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR020934:IPR002222:IPR005732; KEGG: apv:Apar_1157 ribosomal protein S19; PFAM: ribosomal protein S19/S15; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein S19; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004373244.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR002171:IPR005880; KEGG: ccu:Ccur_09970 LSU ribosomal protein L2P; PFAM: ribosomal protein L2; SPTR: uncharacterized protein; TIGRFAM: ribosomal protein L2; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004373245.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR001014:IPR010916:IPR013025; KEGG: shi:Shel_16220 LSU ribosomal protein L23P; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: Ribosomal protein L23 YP_004373246.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: apv:Apar_1160 ribosomal protein L4/L1e; PFAM: ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle YP_004373247.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR019926:IPR019927:IPR000597; KEGG: apv:Apar_1161 ribosomal protein L3; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004373248.1 COGs: COG0051 Ribosomal protein S10; InterPro IPR018268:IPR001848:IPR005731; KEGG: apv:Apar_1163 ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: ribosomal protein S10; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004373249.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004540:IPR005225:IPR004161:IPR 005517:IPR000640; KEGG: apv:Apar_1164 translation elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004373250.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR020606:IPR005717:IPR000235; KEGG: apv:Apar_1165 ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004373251.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR006032:IPR005679; KEGG: apv:Apar_1166 ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004373252.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; InterProIPR011260:IPR012754:IPR007080:IPR000722:IPR 007066:IPR007083:IPR007081:IPR006592; KEGG: apv:Apar_1169 DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase alpha subunit; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; RNA polymerase Rpb1 domain 5; RNA polymerase alpha subunit domain protein; SMART: RNA polymerase I subunit A domain protein; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004373253.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterProIPR007121:IPR010243:IPR007644:IPR007642:IPR 007645:IPR019462:IPR007120:IPR007641; KEGG: apv:Apar_1170 DNA-directed RNA polymerase, beta subunit; PFAM: RNA polymerase Rpb2 domain 6; RNA polymerase beta subunit; RNA polymerase Rpb2 domain 2; RNA polymerase Rpb2 domain 3; DNA-directed RNA polymerase, beta subunit, external 1 domain; RNA polymerase Rpb2 domain 7; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004373254.1 KEGG: afn:Acfer_0081 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088) YP_004373255.1 COGs: COG3862 Uncharacterized protein with conserved CXXC pairs; InterPro IPR013027:IPR000103:IPR012460; KEGG: afn:Acfer_1985 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: protein of unknown function DUF1667; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Protein of unknown function (DUF1667) YP_004373256.1 COGs: COG0579 dehydrogenase; InterPro IPR006076:IPR007419; KEGG: afn:Acfer_1986 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase YP_004373257.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: pzu:PHZ_c2973 beta-lactamase-like protein; SPTR: uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily YP_004373258.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002204:IPR006183:IPR006398:IPR006115; KEGG: ses:SARI_04369 tartronate semialdehyde reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase YP_004373259.1 COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: vha:VIBHAR_06863 glycerate kinase; PFAM: glycerate kinase; PRIAM: Glycerate kinase; SPTR: uncharacterized protein; TIGRFAM: glycerate kinase; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase YP_004373260.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR020625:IPR002220; KEGG: ant:Arnit_1025 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase family YP_004373261.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: gob:Gobs_2393 glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein; PRIAM: Glucarate dehydratase; SPTR: Glucarate dehydratase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain; TIGRFAM: glucarate dehydratase YP_004373262.1 COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: gob:Gobs_2393 glucarate dehydratase; PFAM: Mandelate racemase/muconate lactonizing protein; PRIAM: Glucarate dehydratase; SPTR: Glucarate dehydratase; PFAM: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain YP_004373263.1 COGs: COG2851 H+/citrate symporter; InterPro IPR004680; KEGG: amt:Amet_3213 CitMHS family citrate/H+ symporter; PFAM: Citrate transporter; SPTR: Citrate/H/ symporter; PFAM: Citrate transporter YP_004373264.1 COGs: COG2721 Altronate dehydratase; InterPro IPR017654:IPR013974:IPR007392; KEGG: afn:Acfer_0082 galactarate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; PRIAM: Galactarate dehydratase; SPTR: Galactarate dehydratase; TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus; SAF domain; TIGRFAM: galactarate dehydratase YP_004373265.1 InterPro IPR000182; KEGG: enc:ECL_00350 aminoalkylphosphonic acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Protein PhnO; PFAM: Acetyltransferase (GNAT) family YP_004373266.1 COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599; KEGG: bde:BDP_1379 transcriptional regulator; PFAM: sugar diacid recognition domain protein; SPTR: carbohydrate diacid regulator; PFAM: sugar diacid recognition YP_004373267.1 COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR018130:IPR005835; KEGG: apv:Apar_1293 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: uncharacterized protein; PFAM: Nucleotidyl transferase YP_004373268.1 COGs: COG0222 Ribosomal protein L7/L12; InterPro IPR013823:IPR000206; KEGG: ele:Elen_2330 ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004373269.1 COGs: COG0244 Ribosomal protein L10; InterPro IPR001790; KEGG: shi:Shel_08440 ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: uncharacterized protein; PFAM: Ribosomal protein L10 YP_004373270.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003439:IPR017940:IPR001140:IPR 003593; KEGG: shi:Shel_16460 ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter, ATP-binding protein; PFAM: ABC transporter; ABC transporter transmembrane region YP_004373271.1 COGs: COG3104 Dipeptide/tripeptide permease; KEGG: lin:lin0564 hypothetical protein; SPTR: Amino acid/peptide transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial YP_004373272.1 KEGG: bta:540809 follistatin-like 4 YP_004373273.1 InterPro IPR001387; KEGG: ele:Elen_2391 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix YP_004373274.1 KEGG: ele:Elen_2390 hypothetical protein; SPTR: uncharacterized protein YP_004373275.1 KEGG: dma:DMR_00230 hypothetical protein; SPTR: Iron-sulfur flavoprotein YP_004373276.1 COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: ccu:Ccur_11950 G:T/U mismatch-specific DNA glycosylase; SPTR: G:T/U mismatch-specific DNA glycosylase; PFAM: Uracil DNA glycosylase superfamily YP_004373277.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: bad:BAD_0895 transcriptional regulator; PFAM: ArsR family transcripitonal regulator; SMART: ArsR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, arsR family YP_004373278.1 InterPro IPR012867; KEGG: bad:BAD_0894 hypothetical protein; PFAM: protein of unknown function DUF1648; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1648) YP_004373279.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225:IPR003373:IPR007167:IPR002917:IPR 011619:IPR011642:IPR011640; KEGG: ele:Elen_2325 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; FeoA family protein; Ferrous iron transport protein B domain-containing protein; nucleoside recognition domain protein; Ferrous iron transport B domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; manually curated; PFAM: FeoA domain; Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB YP_004373280.1 COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR006402:IPR005834; KEGG: lac:LBA1068 HAD superfamily hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_004373281.1 COGs: COG2365 Protein tyrosine/serine phosphatase; KEGG: ele:Elen_0136 protein tyrosine/serine phosphatase; SPTR: uncharacterized protein YP_004373282.1 COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: ere:EUBREC_0186 ABC-type uncharacterized transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004373283.1 COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: brm:Bmur_2585 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transport system / permease component YP_004373284.1 COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR000276:IPR007487; KEGG: brm:Bmur_2584 protein of unknown function DUF534; PFAM: protein of unknown function DUF534; SPTR: uncharacterized protein; PFAM: ABC transporter substrate binding protein YP_004373285.1 COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterProIPR002312:IPR004522:IPR006195:IPR004365:IPR 004364; KEGG: apv:Apar_0370 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: uncharacterized protein; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase YP_004373286.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR002143:IPR005878; KEGG: apv:Apar_1173 ribosomal protein L1; PFAM: ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: ribosomal protein L1; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004373287.1 COGs: COG0080 Ribosomal protein L11; InterProIPR020785:IPR006519:IPR020784:IPR020783:IPR 000911; KEGG: apv:Apar_1174 ribosomal protein L11; PFAM: Ribosomal protein L11-like; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004373288.1 COGs: COG0250 Transcription antiterminator; InterPro IPR015869:IPR001062:IPR006645:IPR005824; KEGG: ele:Elen_2130 NusG antitermination factor; PFAM: NGN domain-containing protein; KOW domain protein; SMART: NGN domain-containing protein; SPTR: Transcription antitermination protein nusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: Transcription termination factor nusG; TIGRFAM: transcription termination/antitermination factor NusG YP_004373289.1 InterPro IPR005807:IPR001901; KEGG: apv:Apar_1176 preprotein translocase, SecE subunit; PFAM: protein secE/sec61-gamma protein; SPTR: uncharacterized protein; TIGRFAM: preprotein translocase, SecE subunit; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004373290.1 COGs: COG0267 Ribosomal protein L33; InterPro IPR018264:IPR001705; KEGG: apv:Apar_1177 ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004373291.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004541:IPR005225:IPR004161:IPR 004160; KEGG: apv:Apar_1178 translation elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain-containing protein; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004373292.1 COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: apv:Apar_1179 protein of unknown function DUF901; PFAM: protein of unknown function DUF901; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF901) YP_004373293.1 COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: apv:Apar_1180 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: uncharacterized protein; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3 YP_004373294.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308:IPR015273; KEGG: apv:Apar_1181 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia ; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: uncharacterized protein; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004373295.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; InterPro IPR020555:IPR003526; KEGG: apv:Apar_1183 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004373296.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228; KEGG: ccu:Ccur_13210 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004373297.1 COGs: COG1623 nucleic-acid-binding protein (contains the HHH domain); InterPro IPR003390:IPR018906; KEGG: apv:Apar_1185 DNA integrity scanning protein DisA; PFAM: protein of unknown function DUF147; DNA integrity scanning, DisA, linker region; SPTR: uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; DisA bacterial checkpoint controller linker region YP_004373298.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR018368:IPR001270:IPR004176:IPR003959:IPR 013093:IPR019489:IPR003593; KEGG: apv:Apar_1186 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA) YP_004373299.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: shi:Shel_06480 Na+/melibiose symporter-like transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Na+/melibiose symporter-like transporter; PFAM: Major Facilitator Superfamily YP_004373300.1 COGs: COG3345 Alpha-galactosidase; KEGG: shi:Shel_06470 alpha-galactosidase; SPTR: Alpha-galactosidase; PFAM: Melibiase YP_004373301.1 COGs: COG2211 Na+/melibiose symporter and related transporter; KEGG: shi:Shel_06480 Na+/melibiose symporter-like transporter; SPTR: Na+/melibiose symporter-like transporter YP_004373302.1 InterPro IPR001647; KEGG: oih:OB0328 transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004373303.1 KEGG: shi:Shel_06500 hypothetical protein; SPTR: uncharacterized protein YP_004373304.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: apv:Apar_1220 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373305.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611; KEGG: ccu:Ccur_04400 sugar kinase, ribokinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_004373306.1 InterPro IPR001411:IPR011701; KEGG: blt:Balat_1502 tetracycline resistance protein; PFAM: major facilitator superfamily MFS_1; SPTR: Transporter, major facilitator family; PFAM: Major Facilitator Superfamily YP_004373307.1 COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: cdi:DIP1469 nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Possible ribosylpyrimidine nucleosidase; PFAM: Inosine-uridine preferring nucleoside hydrolase YP_004373308.1 COGs: COG3049 Penicillin V acylase and related amidase; InterPro IPR003199; KEGG: cbf:CLI_2250 linear amide C-N hydrolase; PFAM: Choloylglycine hydrolase; SPTR: Possible Penicillin amidase; PFAM: Linear amide C-N hydrolases, choloylglycine hydrolase family YP_004373309.1 COGs: COG3238 conserved hypothetical protein; InterPro IPR006750; KEGG: pmr:PMI1526 hypothetical protein; PFAM: protein of unknown function DUF606; SPTR: Probable inner membrane protein; PFAM: Protein of unknown function, DUF606 YP_004373310.1 COGs: COG5426 Uncharacterized membrane protein; InterPro IPR010768; KEGG: tbi:Tbis_2586 hypothetical protein; PFAM: protein of unknown function DUF1355; SPTR: Probable cytoplasmic protein; PFAM: Protein of unknown function (DUF1355) YP_004373311.1 COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR018149:IPR002313:IPR006195:IPR004365:IPR 004364; KEGG: ccu:Ccur_13230 lysyl-tRNA synthetase (class II); PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004373312.1 COGs: COG0782 Transcription elongation factor; InterPro IPR018151:IPR006359:IPR001437; KEGG: apv:Apar_1188 transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain-containing protein; SPTR: Transcription elongation factor; TIGRFAM: transcription elongation factor GreA; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004373313.1 InterPro IPR003998:IPR006312:IPR003369; KEGG: shi:Shel_13320 twin arginine-targeting protein translocase, TatA/E family; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: uncharacterized protein; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004373314.1 KEGG: aag:AaeL_AAEL009172 ubiquitin ligase E3 alpha; SPTR: uncharacterized protein YP_004373315.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR004424:IPR006204:IPR013750; KEGG: apv:Apar_0169 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: uncharacterized protein; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004373316.1 COGs: COG4466 Uncharacterized protein; InterPro IPR009366; KEGG: apv:Apar_0168 protein of unknown function DUF1021; PFAM: protein of unknown function DUF1021; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1021) YP_004373317.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR020922:IPR002637; KEGG: apv:Apar_0166 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; PFAM: Ham1 family protein; SPTR: uncharacterized protein; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004373318.1 COGs: COG0689 RNase PH; InterPro IPR018336:IPR002381:IPR001247:IPR015847; KEGG: apv:Apar_0165 ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: Ribonuclease PH; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH YP_004373319.1 COGs: COG0796 Glutamate racemase; InterPro IPR018187:IPR004391:IPR015942; KEGG: ele:Elen_1955 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: uncharacterized protein; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004373320.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200; KEGG: fal:FRAAL6699 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB YP_004373321.1 KEGG: lki:LKI_09490 hypothetical protein; SPTR: uncharacterized protein; PFAM: Telomeric repeat-binding factor 2 YP_004373322.1 KEGG: ele:Elen_1157 hypothetical protein; SPTR: uncharacterized protein YP_004373323.1 KEGG: bln:Blon_1288 metallophosphoesterase; SPTR: uncharacterized protein YP_004373324.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: bad:BAD_0884 integral membrane protein; PFAM: acyltransferase 3; SPTR: uncharacterized protein; PFAM: Acyltransferase family YP_004373325.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: shi:Shel_22030 ornithine/acetylornithine aminotransferase; PFAM: aminotransferase class-III; SPTR: uncharacterized protein; PFAM: Aminotransferase class-III YP_004373326.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR001057:IPR004662:IPR001048:IPR011148; KEGG: ele:Elen_2342 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase YP_004373327.1 COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); InterPro IPR002813; KEGG: ele:Elen_2343 arginine biosynthesis bifunctional protein ArgJ; PFAM: arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_004373328.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000706:IPR000534:IPR012280; KEGG: ele:Elen_2344 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004373329.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211:IPR001670; KEGG: apv:Apar_0133 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase YP_004373330.1 KEGG: apv:Apar_0132 response regulator receiver and SARP domain protein; SPTR: uncharacterized protein YP_004373331.1 KEGG: apv:Apar_0131 hypothetical protein; SPTR: uncharacterized protein YP_004373332.1 COGs: COG3153 acetyltransferase; InterPro IPR000182; KEGG: dae:Dtox_0635 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: Acetyltransferase (GNAT) family YP_004373333.1 COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: shi:Shel_19890 glutamine synthetase; PFAM: glutamine synthetase catalytic region; SPTR: uncharacterized protein; manually curated; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal YP_004373334.1 COGs: COG2848 conserved hypothetical protein; InterPro IPR007841; KEGG: apv:Apar_1221 hypothetical protein; PFAM: protein of unknown function DUF711; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR (DUF711) YP_004373335.1 KEGG: ele:Elen_1137 hypothetical protein; SPTR: uncharacterized protein YP_004373336.1 KEGG: tpr:Tpau_0465 protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: uncharacterized protein YP_004373337.1 COGs: COG1534 RNA-binding protein containing KH domain possibly ribosomal protein; InterPro IPR001890; KEGG: bad:BAD_0960 hypothetical protein; PFAM: protein of unknown function UPF0044; SPTR: uncharacterized protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: RNA-binding protein, YhbY family YP_004373338.1 COGs: COG3629 DNA-binding transcriptional activator of the SARP family; KEGG: ele:Elen_2003 SARP family transcriptional regulator; SPTR: uncharacterized protein; PFAM: Bacterial transcriptional activator domain YP_004373339.1 COGs: COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR018322:IPR006148; KEGG: apv:Apar_0167 glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; SPTR: uncharacterized protein; TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase YP_004373340.1 COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127; KEGG: eca:ECA1870 PTS system beta-glucoside-specific transporter subunits IIABC; PFAM: sugar-specific permease EIIA 1 domain; SPTR: uncharacterized protein; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component; TC 4.A.1 YP_004373341.1 COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR005841:IPR006352:IPR005844:IPR 005845:IPR005846:IPR005843; KEGG: ele:Elen_0717 phosphoglucosamine mutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: uncharacterized protein; TIGRFAM: phosphoglucosamine mutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004373342.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR020574:IPR000754; KEGG: apv:Apar_1249 ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16 YP_004373343.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005822:IPR005823; KEGG: apv:Apar_1250 ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: ribosomal protein L13; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type; ribosomal protein L13, archaeal/eukaryotic YP_004373344.1 COGs: COG4667 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: apv:Apar_1253 patatin; PFAM: Patatin; SPTR: uncharacterized protein; tmRNA as predicted by Rfam (RF00023), score 142.48; PFAM: Patatin-like phospholipase YP_004373345.1 KEGG: bll:BLJ_0195 colicin uptake membrane protein; SPTR: uncharacterized protein YP_004373346.1 KEGG: ele:Elen_2959 hypothetical protein; SPTR: uncharacterized protein; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt) YP_004373347.1 KEGG: ele:Elen_2125 hypothetical protein; SPTR: uncharacterized protein YP_004373348.1 InterPro IPR006626; KEGG: mmi:MMAR_5294 PE-PGRS family protein; SPTR: listeria/Bacterioides repeat-containing domain protein YP_004373349.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: bhy:BHWA1_01862 Tdh, threonine dehydrogenase-like Zn-dependent dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004373350.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterProIPR013838:IPR017958:IPR004413:IPR006075:IPR 018027; KEGG: ele:Elen_1074 glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB region; Asn/Gln amidotransferase; SPTR: uncharacterized protein; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit YP_004373351.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR005829:IPR004412:IPR000120; KEGG: shi:Shel_21770 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; PFAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, A subunit; PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit YP_004373352.1 InterPro IPR003837; KEGG: ele:Elen_1072 glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; SPTR: uncharacterized protein; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, C subunit; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit YP_004373353.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078; KEGG: lmh:LMHCC_1331 phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase family protein; PFAM: Phosphoglycerate mutase family YP_004373354.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698:IPR000032; KEGG: bll:BLJ_0238 phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: uncharacterized protein; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004373355.1 COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127; KEGG: apv:Apar_0904 PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease EIIA 1 domain; SPTR: uncharacterized protein; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component; TC 4.A.1 YP_004373356.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR018113:IPR001996:IPR013013:IPR003352; KEGG: lga:LGAS_1669 trehalose PTS trehalose component IIBC; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB YP_004373357.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: ere:EUBREC_3687 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 1; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolase family 1 YP_004373358.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lpj:JDM1_2505 cellobiose phosphotransferase system IIC component; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373359.1 KEGG: smu:SMU.1597c hypothetical protein; SPTR: uncharacterized protein YP_004373360.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: apv:Apar_1257 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373361.1 COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: ljo:LJ0190 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA, cellobiose specific; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit YP_004373362.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR013011:IPR011608:IPR007737; KEGG: bpu:BPUM_3507 transcription antiterminator BglG; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373363.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: cac:CA_C1405 beta-glucosidase; PFAM: glycoside hydrolase family 1; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolase family 1 YP_004373364.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281; KEGG: cbe:Cbei_4848 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; SPTR: uncharacterized protein; PFAM: Helix-turn-helix domain, rpiR family YP_004373365.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003439:IPR017940:IPR001140:IPR 003593; KEGG: apv:Apar_0422 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004373366.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003439:IPR017940:IPR001140:IPR 003593; KEGG: apv:Apar_0421 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004373367.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR018239:IPR001679:IPR001357:IPR013839:IPR 004150:IPR004149:IPR013840; KEGG: apv:Apar_1111 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase ; BRCT domain protein; SPTR: DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004373368.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001940:IPR001478:IPR001254; KEGG: ele:Elen_2476 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: uncharacterized protein; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_004373369.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: apv:Apar_0432 two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator domain-containing protein; SPTR: uncharacterized protein; PFAM: Transcriptional regulatory protein, C terminal YP_004373370.1 COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146; KEGG: ele:Elen_2016 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: uncharacterized protein; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain YP_004373371.1 KEGG: apv:Apar_0427 hypothetical protein; SPTR: uncharacterized protein YP_004373372.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR005225:IPR003373:IPR002917:IPR011619:IPR 011642:IPR011640; KEGG: apv:Apar_0971 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain-containing protein; nucleoside recognition domain protein; Ferrous iron transport B domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain YP_004373373.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: dhd:Dhaf_3460 FeoA family protein; PFAM: FeoA family protein; SPTR: uncharacterized protein; PFAM: FeoA domain YP_004373374.1 InterPro IPR007167; KEGG: apv:Apar_0973 FeoA family protein; PFAM: FeoA family protein; SPTR: uncharacterized protein; PFAM: FeoA domain YP_004373375.1 COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250:IPR014628; KEGG: apv:Apar_0314 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: uncharacterized protein; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I YP_004373376.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterProIPR002312:IPR004524:IPR006195:IPR004365:IPR 004364:IPR004115; KEGG: apv:Apar_0420 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; GAD domain protein; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004373377.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR018313:IPR001638:IPR001320; KEGG: ele:Elen_0237 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004373378.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR002173:IPR010065:IPR000515; KEGG: ele:Elen_0238 polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_004373379.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: ele:Elen_0239 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Amino acid ABC transporter ATP-binding protein, PAAT family TC 3.A.1.3.-); PFAM: ABC transporter YP_004373380.1 InterPro IPR011701; KEGG: lpj:JDM1_1093 transport protein; PFAM: major facilitator superfamily MFS_1; SPTR: Transport protein; PFAM: Major Facilitator Superfamily YP_004373381.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: lga:LGAS_0732 AraC-like transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004373382.1 COGs: COG0657 Esterase/lipase; KEGG: lhe:lhv_1434 lipase; SPTR: Triacylglycerol lipase; PFAM: alpha/beta hydrolase fold YP_004373383.1 COGs: COG2352 Phosphoenolpyruvate carboxylase; InterPro IPR018129:IPR001449:IPR021135; KEGG: ele:Elen_2973 phosphoenolpyruvate carboxylase; PFAM: Phosphoenolpyruvate carboxylase, C-terminal region; PRIAM: Phosphoenolpyruvate carboxylase; SPTR: uncharacterized protein; PFAM: Phosphoenolpyruvate carboxylase YP_004373384.1 COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR006195:IPR002314:IPR004154:IPR 004516; KEGG: apv:Apar_0403 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004373385.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: apv:Apar_1094 sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; SPTR: uncharacterized protein; TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004373386.1 InterPro IPR003998:IPR003369; KEGG: ele:Elen_2832 sec-independent translocation protein MttA/Hcf106; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: uncharacterized protein; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004373387.1 InterPro IPR003658:IPR002645; KEGG: apv:Apar_1096 anti-sigma-factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_004373388.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; KEGG: apv:Apar_1098 GntR family transcriptional regulator; SPTR: uncharacterized protein YP_004373389.1 KEGG: apv:Apar_1099 hypothetical protein; SPTR: uncharacterized protein YP_004373390.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: apv:Apar_0320 ROK family protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase) YP_004373391.1 COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: snc:HMPREF0837_10019 PTS family cellobiose transporter subunit IIA; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: PTS family cellobiose porter component IIA; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit YP_004373392.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: apv:Apar_0080 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, lactose/cellobiose family IIB component YP_004373393.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: apv:Apar_0079 PTS system, lactose/cellobiose family IIC subunit; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, IIC component; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373394.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: apv:Apar_0078 glycoside hydrolase family 1; PFAM: glycoside hydrolase family 1; SPTR: 6-phospho-beta-galactosidase; PFAM: Glycosyl hydrolase family 1 YP_004373395.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: apv:Apar_0077 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004373396.1 COGs: COG1668 ABC-type Na+ efflux pump permease component; KEGG: ele:Elen_1131 ABC-2 type transporter; SPTR: ABC-2 type transporter YP_004373397.1 COGs: COG4555 ABC-type Na+ transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: bts:Btus_3144 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter YP_004373398.1 InterPro IPR001845; KEGG: cby:CLM_0725 hypothetical protein; PFAM: ArsR family transcripitonal regulator; SMART: ArsR family transcripitonal regulator; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, arsR family YP_004373399.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003439:IPR017940:IPR001140:IPR 003593; KEGG: cbi:CLJ_B0700 ABC transporter, ATP-binding protein/permease protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004373400.1 KEGG: apv:Apar_1053 hypothetical protein; SPTR: uncharacterized protein YP_004373401.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR005146:IPR 005147; KEGG: apv:Apar_1054 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004373402.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529:IPR006195:IPR004188:IPR002319; KEGG: apv:Apar_1055 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; SPTR: uncharacterized protein; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004373403.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: str:Sterm_3214 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter family YP_004373404.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: str:Sterm_3215 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004373405.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471:IPR001395; KEGG: str:Sterm_3216 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family YP_004373406.1 COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR002139:IPR011611; KEGG: set:SEN1754 sugar kinase; PFAM: PfkB domain protein; SPTR: sugar kinase; PFAM: pfkB family carbohydrate kinase YP_004373407.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: ecm:EcSMS35_1418 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: YdjI protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004373408.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: ecg:E2348C_1901 predicted oxidoreductase, Zn-dependent and NAD(P)-binding; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Predicted oxidoreductase, Zn-dependent and NAD(P)-binding; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004373409.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: str:Sterm_3220 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004373410.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: str:Sterm_3221 alcohol dehydrogenase zinc-binding domain protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004373411.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR000291:IPR011761:IPR011127:IPR011095; KEGG: apv:Apar_0319 D-alanine--D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; PFAM: D-ala D-ala ligase N-terminus; D-ala D-ala ligase C-terminus YP_004373412.1 COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: apv:Apar_0318 GntR family transcriptional regulator; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I and II; PFAM: Aminotransferase class I and II YP_004373413.1 COGs: COG2317 Zn-dependent carboxypeptidase; InterPro IPR001333; KEGG: apv:Apar_0317 carboxypeptidase Taq; PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; PRIAM: Carboxypeptidase Taq; SPTR: uncharacterized protein; PFAM: Carboxypeptidase Taq (M32) metallopeptidase YP_004373414.1 InterPro IPR003006:IPR000620; KEGG: ele:Elen_1424 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family YP_004373415.1 COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR007863:IPR013578; KEGG: shi:Shel_20700 predicted Zn-dependent peptidase, insulinase; PFAM: Peptidase M16C associated domain protein; peptidase M16 domain protein; SPTR: uncharacterized protein; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain YP_004373416.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: apv:Apar_0125 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: uncharacterized protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold YP_004373417.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329:IPR002121:IPR014021:IPR001650:IPR 011545:IPR018982:IPR014001; KEGG: ele:Elen_1066 ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; RQC domain; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase ; HRDC domain protein; SPTR: uncharacterized protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family YP_004373418.1 InterPro IPR003838; KEGG: ele:Elen_2587 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004373419.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: ele:Elen_2588 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004373420.1 COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR010766:IPR004097; KEGG: apv:Apar_0296 manganese-dependent inorganic pyrophosphatase; PFAM: CBS domain containing protein; DRTGG domain protein; DHHA2 domain protein; PRIAM: Inorganic diphosphatase; SMART: CBS domain containing protein; SPTR: Possible inorganic diphosphatase; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain YP_004373421.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR004576:IPR014021:IPR001650:IPR003711:IPR 011545:IPR005118:IPR014001; KEGG: apv:Apar_0124 transcription-repair coupling factor; PFAM: DEAD/DEAH box helicase domain protein; transcription factor CarD; helicase domain protein; TRCF domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004373422.1 COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557:IPR001236; KEGG: blt:Balat_0321 L-lactate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: uncharacterized protein; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain YP_004373423.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003439:IPR003838:IPR003593; KEGG: cpy:Cphy_0192 ABC transporter related; PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Predicted permease YP_004373424.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: cpy:Cphy_0193 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Predicted permease YP_004373425.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829:IPR001789:IPR001867; KEGG: cpy:Cphy_0196 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004373426.1 COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR005467:IPR003660:IPR003661:IPR 003594; KEGG: cpy:Cphy_0195 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: uncharacterized protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004373427.1 COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: lcz:LCAZH_0578 Mg2+ transporter-C (MgtC) family; PFAM: MgtC/SapB transporter; SPTR: uncharacterized protein; PFAM: MgtC family YP_004373428.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: cbe:Cbei_2191 RpiR family transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: RpiR family transcriptional regulator; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004373429.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; InterPro IPR001202; KEGG: lrl:LC705_00435 L-ascorbate 6-phosphate lactonase; SPTR: Probable L-ascorbate-6-phosphate lactonase UlaG YP_004373430.1 InterPro IPR013011:IPR003501; KEGG: lrl:LC705_00434 PTS system transporter subunit IIB; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system, lactose/cellobiose-specific IIB component; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373431.1 COGs: COG3037 conserved hypothetical protein; KEGG: lrl:LC705_00433 PTS system transporter subunit IIC; SPTR: Ascorbate-specific PTS system enzyme IIC; PFAM: PTS system sugar-specific permease component YP_004373432.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: lrl:LC705_00432 PTS system transporter subunit IIA; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Ascorbate-specific phosphotransferase enzyme iia component; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373433.1 COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006183:IPR004849:IPR006115:IPR006114; KEGG: bmq:BMQ_1336 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain-containing protein; SPTR: 6-phosphogluconate dehydrogenase; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating) YP_004373434.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: bpy:Bphyt_0295 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family YP_004373435.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: bpy:Bphyt_0294 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family YP_004373436.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: afr:AFE_0603 cation ABC transporter, ATP-binding protein, PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Cation ABC transporter, ATP-binding protein, ; PFAM: ABC transporter YP_004373437.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterProIPR018120:IPR006128:IPR006311:IPR017909:IPR 006127; KEGG: afr:AFE_0602 cation ABC transporter, periplasmic cation-binding protein, PFAM: periplasmic solute binding protein; SPTR: Cation ABC transporter, periplasmic cation-binding protein, ; PFAM: Periplasmic solute binding protein family YP_004373438.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; KEGG: ccu:Ccur_04330 Fe2+/Zn2+ uptake regulation protein; SPTR: ferric uptake regulation protein; PFAM: Ferric uptake regulator family YP_004373439.1 KEGG: coc:Coch_2162 hypothetical protein; SPTR: uncharacterized protein YP_004373440.1 KEGG: shi:Shel_22530 hypothetical protein; SPTR: uncharacterized protein YP_004373441.1 COGs: COG3023 Negative regulator of beta-lactamase expression; InterPro IPR002502; KEGG: shi:Shel_22540 negative regulator of beta-lactamase expression; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2; SPTR: Negative regulator of beta-lactamase expression; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004373442.1 KEGG: ele:Elen_2329 hypothetical protein; SPTR: uncharacterized protein YP_004373443.1 COGs: COG0270 Site-specific DNA methylase; InterPro IPR018117:IPR001525; KEGG: aba:Acid345_4264 DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: uncharacterized protein; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm) YP_004373444.1 COGs: COG3731 Phosphotransferase system sorbitol-specific component IIA; InterPro IPR004716; KEGG: lrh:LGG_02717 PTS system glucitol/sorbitol-specific transporter subunit IIA; PFAM: PTS system glucitol/sorbitol-specific IIA component; SPTR: Sorbitol PTS, EIIA; PFAM: PTS system glucitol/sorbitol-specific IIA component YP_004373445.1 COGs: COG3732 Phosphotransferase system sorbitol-specific component IIBC; InterPro IPR004702:IPR011618:IPR011638; KEGG: lca:LSEI_2722 sorbitol PTS, EIIBC; PFAM: Sorbitol phosphotransferase protein II domain-containing protein; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Sorbitol PTS, EIIBC; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase enzyme II C-terminus; Sorbitol phosphotransferase enzyme II N-terminus; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC component YP_004373446.1 COGs: COG3730 Phosphotransferase system sorbitol-specific component IIC; InterPro IPR004699; KEGG: lca:LSEI_2723 sorbitol PTS, EIIC; PFAM: PTS system protein II sorbitol-specific factor; SPTR: Sorbitol PTS, EIIC; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system enzyme II sorbitol-specific factor; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC component YP_004373447.1 InterPro IPR009693; KEGG: lrh:LGG_02720 glucitol operon activator; PFAM: Glucitol operon activator; SPTR: Glucitol operon activator; PFAM: Glucitol operon activator protein (GutM) YP_004373448.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR011608; KEGG: lcz:LCAZH_2731 sorbitol operon transcription regulator; PFAM: PRD domain protein; SPTR: Sorbitol operon transcription activator; PFAM: HTH domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373449.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002198:IPR002347; KEGG: lrh:LGG_02722 sorbitol-6-phosphate 2-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Sorbitol-6-phosphate 2-dehydrogenase; PFAM: short chain dehydrogenase YP_004373450.1 COGs: COG1874 Beta-galactosidase; InterPro IPR001944; KEGG: smb:smi_0079 beta-galactosidase 3; PFAM: glycoside hydrolase family 35; PRIAM: Beta-galactosidase; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolases family 35 YP_004373451.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: efa:EF1804 PTS system, IIB component; PFAM: PTS system sorbose subfamily IIB component; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system sorbose specific IIB component; PFAM: PTS system sorbose subfamily IIB component YP_004373452.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700:IPR017441; KEGG: efa:EF1803 PTS system, IIC component; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004373453.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: efa:EF1802 PTS system, IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004373454.1 KEGG: tva:TVAG_049230 Sec1 family protein; SPTR: uncharacterized protein YP_004373455.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: sss:SSUSC84_0386 GntR family regulatory protein; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004373456.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR005467:IPR004358; KEGG: ccu:Ccur_00270 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004373457.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR005829:IPR001867; KEGG: apv:Apar_1044 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004373458.1 InterPro IPR018247; KEGG: ccu:Ccur_00290 UBA/Ts-N domain-containing protein; SPTR: UBA/TS-N domain YP_004373459.1 COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: apv:Apar_1280 KDPG and KHG aldolase; PFAM: KDPG and KHG aldolase; SPTR: KDPG and KHG aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_004373460.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR020625:IPR002220; KEGG: apv:Apar_1281 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: Dihydrodipicolinate synthetase; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_004373461.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: rsd:TGRD_434 PTS mannose/fructose/N-acetylgalactosamine-specific component IIA; PFAM: PTS system fructose subfamily IIA component; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004373462.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: tit:Thit_0161 phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004373463.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: ecz:ECS88_3861 phosphotransferase system enzyme IID; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004373464.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: ecz:ECS88_3860 phosphotransferase system enzyme IIC; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004373465.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: str:Sterm_3863 PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component; SPTR: uncharacterized protein; PFAM: PTS system sorbose subfamily IIB component YP_004373466.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR018506:IPR001347; KEGG: apv:Apar_1282 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); SPTR: Sugar isomerase (SIS); PFAM: SIS domain YP_004373467.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: apv:Apar_1220 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373468.1 COGs: COG0218 GTPase; InterPro IPR000276:IPR002917:IPR019987:IPR005225; KEGG: apv:Apar_0361 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC; small GTP-binding protein; PFAM: Ferrous iron transport protein B; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain YP_004373469.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845:IPR010049; KEGG: blt:Balat_0340 5-methylthioadenosine nucleosidase; PFAM: purine or other phosphorylase family 1; PRIAM: Adenosylhomocysteine nucleosidase; SPTR: uncharacterized protein; TIGRFAM: MTA/SAH nucleosidase; PFAM: Phosphorylase superfamily; TIGRFAM: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_004373470.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: cbe:Cbei_0763 RpiR family transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: uncharacterized protein; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004373471.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: lsg:lse_2122 fructose-bisphosphate aldolase, class II family; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_004373472.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterPro IPR013014:IPR003352:IPR006327; KEGG: str:Sterm_2751 PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; SPTR: uncharacterized protein; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, fructose subfamily, IIC component; TC 4.A.2.1.9 YP_004373473.1 COGs: COG1445 Phosphotransferase system fructose-specific component IIB; InterPro IPR013011:IPR003353; KEGG: lin:lin2241 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, fructose-specific, IIB component YP_004373474.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178:IPR004715; KEGG: lrh:LGG_00409 PTS system fructose-specific transporter subunit IIA; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: uncharacterized protein; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component YP_004373475.1 COGs: COG3533 conserved hypothetical protein; InterPro IPR012878; KEGG: gyc:GYMC61_2720 protein of unknown function DUF1680; PFAM: protein of unknown function DUF1680; SPTR: uncharacterized protein araN; PFAM: glycosyl hydrolase of unknown function (DUF1680) YP_004373476.1 COGs: COG3104 Dipeptide/tripeptide permease; InterPro IPR011701; KEGG: gka:GK2020 di-tripeptide ABC transporter (permease); PFAM: major facilitator superfamily MFS_1; SPTR: Amino acid/peptide transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: amino acid/peptide transporter (Peptide:H+ symporter), bacterial YP_004373477.1 COGs: COG3533 conserved hypothetical protein; InterPro IPR012878; KEGG: ami:Amir_4712 protein of unknown function DUF1680; PFAM: protein of unknown function DUF1680; SPTR: Secreted protein; PFAM: glycosyl hydrolase of unknown function (DUF1680) YP_004373478.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR018060:IPR000005:IPR020449; KEGG: ppe:PEPE_0154 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; manually curated; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family YP_004373479.1 KEGG: scl:sce5364 hypothetical protein; SPTR: uncharacterized protein YP_004373480.1 COGs: COG3534 Alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: gtn:GTNG_1791 alpha-L-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase domain protein; PRIAM: Alpha-N-arabinofuranosidase; SMART: alpha-L-arabinofuranosidase domain protein; SPTR: Alpha-N-arabinofuranosidase; PFAM: Alpha-L-arabinofuranosidase C-terminus YP_004373481.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cpy:Cphy_1578 ROK family protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004373482.1 COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: cbe:Cbei_4847 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 4; SPTR: 6-phospho-beta-glucosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain YP_004373483.1 KEGG: lpj:JDM1_1169 hypothetical protein; SPTR: uncharacterized protein lp_1397; PFAM: Domain of unknown function (DUF3284) YP_004373484.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: lcr:LCRIS_00895 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 1; SPTR: 6-phospho-beta-glucosidase; PFAM: Glycosyl hydrolase family 1 YP_004373485.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lpj:JDM1_1172 beta-glucosides PTS, EIIC; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Beta-glucosides PTS; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373486.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: ssa:SSA_1147 beta-glucosides PTS, EIIB, PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373487.1 COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: lgs:LEGAS_1790 PTS system lactose transporter subunit/cellobiose transporter subunit IIA; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: uncharacterized protein; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit; TC 4.A.3.2.1 YP_004373488.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR013011:IPR011608; KEGG: bpu:BPUM_3507 transcription antiterminator BglG; PFAM: PRD domain protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373489.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR001989:IPR007197:IPR012838; KEGG: apv:Apar_0654 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM domain protein; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: uncharacterized protein; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: Radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme YP_004373490.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR001150:IPR019777; KEGG: apv:Apar_0655 autonomous glycyl radical cofactor GrcA; PFAM: formate C-acetyltransferase glycine radical; SPTR: uncharacterized protein; PFAM: Glycine radical YP_004373491.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR005949:IPR004184:IPR001150; KEGG: apv:Apar_0656 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: formate acetyltransferase; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1 YP_004373492.1 InterPro IPR003838; KEGG: ccu:Ccur_03350 predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease YP_004373493.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ccu:Ccur_03360 ABC-type antimicrobial peptide transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004373494.1 COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: apv:Apar_0055 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: uncharacterized protein; PFAM: SPFH domain / Band 7 family YP_004373495.1 KEGG: apv:Apar_0056 hypothetical protein; SPTR: uncharacterized protein YP_004373496.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: apv:Apar_0057 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004373497.1 InterPro IPR013838; KEGG: ele:Elen_2748 hypothetical protein; SPTR: uncharacterized protein YP_004373498.1 COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR006132:IPR006131:IPR006130:IPR002292; KEGG: ele:Elen_0676 putrescine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: Ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004373499.1 KEGG: cai:Caci_5967 hypothetical protein; SPTR: uncharacterized protein YP_004373500.1 COGs: COG3727 DNA G:T-mismatch repair endonuclease; InterPro IPR020084:IPR000086:IPR004603:IPR020476; KEGG: ele:Elen_2144 DNA mismatch endonuclease Vsr; PFAM: NUDIX hydrolase; DNA mismatch endonuclease vsr; SPTR: uncharacterized protein; TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: NUDIX domain; DNA mismatch endonuclease Vsr; TIGRFAM: DNA mismatch endonuclease Vsr; mutator mutT protein YP_004373501.1 COGs: COG1511 membrane protein; InterPro IPR013525:IPR017500:IPR017501; KEGG: bde:BDP_0048 membrane protein; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; TIGRFAM: YhgE/Pip N-terminal domain protein; YhgE/Pip C-terminal domain protein; PFAM: Protein of unknown function (DUF3533); ABC-2 type transporter; TIGRFAM: YhgE/Pip C-terminal domain; YhgE/Pip N-terminal domain YP_004373502.1 COGs: COG1511 membrane protein; InterPro IPR013525:IPR017500:IPR017501; KEGG: blo:BL0138 hypothetical protein; PFAM: ABC-2 type transporter; SPTR: uncharacterized protein; TIGRFAM: YhgE/Pip N-terminal domain protein; YhgE/Pip C-terminal domain protein; PFAM: ABC-2 type transporter; TIGRFAM: YhgE/Pip C-terminal domain; YhgE/Pip N-terminal domain YP_004373503.1 COGs: COG0326 Molecular chaperone HSP90 family; InterProIPR003594:IPR001404:IPR019805:IPR020576:IPR 020575; KEGG: ele:Elen_0192 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein YP_004373504.1 COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: apv:Apar_0434 protein of unknown function DUF195; PFAM: protein of unknown function DUF195; SPTR: uncharacterized protein; PFAM: RmuC family YP_004373505.1 COGs: COG0177 EndoIII-related endonuclease; InterProIPR003265:IPR003651:IPR004035:IPR004036:IPR 005759; KEGG: apv:Apar_0123 endonuclease III; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: uncharacterized protein; TIGRFAM: endonuclease III; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004373506.1 KEGG: bch:Bcen2424_4152 di-haem cytochrome c peroxidase; SPTR: uncharacterized protein YP_004373507.1 KEGG: lmo:lmo1036 hypothetical protein; SPTR: uncharacterized protein YP_004373508.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR001996:IPR013013:IPR018113:IPR003352; KEGG: sga:GALLO_1605 PTS system, beta-glucoside specific, EIIBC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: uncharacterized protein; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB YP_004373509.1 KEGG: brm:Bmur_0482 hypothetical protein; SPTR: uncharacterized protein YP_004373510.1 KEGG: bhy:BHWA1_00023 hypothetical protein; SPTR: uncharacterized protein YP_004373512.1 COGs: COG2936 acyl esterase; InterPro IPR013736:IPR005674; KEGG: blj:BLD_1942 acyl esterase; PFAM: X-Pro dipeptidyl-peptidase domain protein; SPTR: Hydrolase, CocE/NonD family; TIGRFAM: hydrolase CocE/NonD family protein; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: hydrolase, CocE/NonD family YP_004373513.1 COGs: COG4099 peptidase; KEGG: lsg:lse_2259 hypothetical protein; SPTR: uncharacterized protein; PFAM: Esterase PHB depolymerase YP_004373514.1 InterPro IPR011701; KEGG: ljo:LJ0407 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004373515.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR018062:IPR000005; KEGG: lcr:LCRIS_01608 AraC-type DNA-binding domain-containing proteins; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC-type DNA-binding domain-containing proteins; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_004373516.1 COGs: COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; InterPro IPR018120:IPR001360; KEGG: efa:EF0271 6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 1; SPTR: uncharacterized protein; PFAM: Glycosyl hydrolase family 1 YP_004373517.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR002731:IPR000600; KEGG: cbe:Cbei_0443 ROK family protein; PFAM: ROK family protein; ATPase BadF/BadG/BcrA/BcrD type; SPTR: uncharacterized protein; PFAM: ROK family YP_004373518.1 KEGG: bde:BDP_1668 alpha-L-rhamnosidase domain protein; SPTR: uncharacterized protein YP_004373519.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: bde:BDP_1670 ScrT sucrose transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004373520.1 InterPro IPR001647; KEGG: bde:BDP_1669 TetR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, tetR family YP_004373521.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR018109:IPR013221:IPR013564; KEGG: blo:BL0430 hypothetical protein; PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain YP_004373522.1 COGs: COG3442 glutamine amidotransferase; InterPro IPR017929:IPR011698; KEGG: bln:Blon_0229 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ domain protein glutamine amidotransferase; SPTR: CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ-like glutamine amidotransferase domain YP_004373523.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR005829:IPR011701; KEGG: bde:BDP_0162 MFS-type transporter; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004373524.1 COGs: COG0554 Glycerol kinase; InterPro IPR018483:IPR018484:IPR018485; KEGG: cth:Cthe_2442 carbohydrate kinase, FGGY; PFAM: Carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004373525.1 COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: gym:GYMC10_3004 transketolase domain protein; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, C-subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain YP_004373526.1 COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: lmc:Lm4b_01052 transketolase; PFAM: Transketolase domain-containing protein; SPTR: Transketolase, N-subunit; PFAM: Transketolase, thiamine diphosphate binding domain YP_004373527.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: lmy:LM5923_1067 hypothetical protein; SPTR: uncharacterized protein YP_004373528.1 COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: str:Sterm_3348 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system cellobiose-specific component IIB; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit YP_004373529.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: bcu:BCAH820_3046 PTS system, IIC component; PFAM: phosphotransferase system EIIC; SPTR: Lichenan permease IIC component; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373530.1 KEGG: sli:Slin_6336 hypothetical protein; SPTR: Alpha-L-rhamnosidase domain protein YP_004373531.1 KEGG: fal:FRAAL0319 signal peptide; SPTR: uncharacterized protein YP_004373532.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: ere:EUBREC_2561 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373533.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: apv:Apar_0150 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373534.1 COGs: COG1592 Rubrerythrin; InterPro IPR004039:IPR009040:IPR003251; KEGG: apv:Apar_0122 rubrerythrin; PFAM: Rubrerythrin; SPTR: uncharacterized protein; PFAM: Rubrerythrin YP_004373535.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265:IPR004036; KEGG: apv:Apar_0121 HhH-GPD family protein; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: uncharacterized protein; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004373536.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: apv:Apar_0120 transcriptional regulator, BadM/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: uncharacterized protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004373537.1 InterPro IPR000182; KEGG: efa:EF0698 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase; PFAM: Acetyltransferase (GNAT) family YP_004373538.1 COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: apv:Apar_1322 phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004373539.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: apv:Apar_1323 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004373540.1 COGs: COG3275 regulator of cell autolysis; InterPro IPR003594:IPR005467:IPR010559:IPR004358; KEGG: apv:Apar_1324 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004373541.1 KEGG: ccu:Ccur_01130 hypothetical protein; SPTR: uncharacterized protein YP_004373542.1 COGs: COG4708 membrane protein; InterPro IPR010387; KEGG: apv:Apar_1325 protein of unknown function DUF988; PFAM: protein of unknown function DUF988; SPTR: uncharacterized protein; PFAM: QueT transporter YP_004373543.1 KEGG: apv:Apar_1108 hypothetical protein; SPTR: uncharacterized protein YP_004373544.1 KEGG: ele:Elen_1636 hypothetical protein; SPTR: uncharacterized protein YP_004373545.1 COGs: COG0549 Carbamate kinase; InterPro IPR003964:IPR000623:IPR001048; KEGG: shi:Shel_05980 carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Carbamate kinase; SPTR: uncharacterized protein; manually curated; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase YP_004373546.1 COGs: COG2055 Malate/L-lactate dehydrogenase; InterPro IPR003767:IPR017590; KEGG: lsp:Bsph_2900 ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: ureidoglycolate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; TIGRFAM: ureidoglycolate dehydrogenase YP_004373547.1 KEGG: efa:EF0384 hypothetical protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2877) YP_004373548.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR009499; KEGG: efa:EF0383 hypothetical protein; PFAM: protein of unknown function DUF1116; SPTR: uncharacterized protein; PFAM: CoA binding domain; CoA-ligase; Protein of unknown function (DUF1116) YP_004373549.1 COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010158:IPR002933:IPR011650; KEGG: kpu:KP1_1372 allantoate amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-carbamoyl-L-amino-acid hydrolase; SPTR: Allantoate amidohydrolase; TIGRFAM: amidase, hydantoinase/carbamoylase family; PFAM: Peptidase family M20/M25/M40; TIGRFAM: allantoate amidohydrolase; amidase, hydantoinase/carbamoylase family YP_004373550.1 COGs: COG1953 Cytosine/uracil/thiamine/allantoin permease; InterPro IPR001248; KEGG: efa:EF3000 allantoin permease; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: Cytosine/purine permease; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: NCS1 nucleoside transporter family YP_004373551.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR017593; KEGG: efa:EF2999 allantoinase; PFAM: amidohydrolase; SPTR: Allantoinase; TIGRFAM: allantoinase; PFAM: Amidohydrolase family; TIGRFAM: allantoinase; dihydroorotase, multifunctional complex type YP_004373552.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: efa:EF2992 major facilitator family transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily transporter; PFAM: Major Facilitator Superfamily YP_004373553.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR005829:IPR011701; KEGG: efa:EF2992 major facilitator family transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily YP_004373554.1 COGs: COG3257 Uncharacterized protein possibly involved in glyoxylate utilization; InterPro IPR013096:IPR017627; KEGG: ecg:E2348C_0448 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: Allantoin catabolism protein; TIGRFAM: allantoin catabolism protein; PFAM: Cupin domain; TIGRFAM: allantoin catabolism protein YP_004373555.1 InterPro IPR012914; KEGG: efa:EF0382 hypothetical protein; PFAM: purine catabolism PurC domain protein; SPTR: uncharacterized protein; PFAM: Purine catabolism regulatory protein-like family YP_004373556.1 COGs: COG0657 Esterase/lipase; KEGG: sab:SAB0271c hypothetical protein; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold YP_004373557.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: lsp:Bsph_2893 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004373558.1 COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: afn:Acfer_2083 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004373559.1 COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR018211:IPR001670:IPR013460; KEGG: ere:EUBREC_1091 L-1,2-propanediol oxidoreductase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; TIGRFAM: lactaldehyde reductase; PFAM: Iron-containing alcohol dehydrogenase; TIGRFAM: lactaldehyde reductase YP_004373560.1 KEGG: afo:Afer_0862 hypothetical protein; SPTR: uncharacterized protein YP_004373561.1 KEGG: lch:Lcho_3430 filamentous haemagglutinin outer membrane protein; SPTR: Filamentous haemagglutinin family outer membrane protein YP_004373562.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR011895:IPR017900:IPR002880:IPR 019752:IPR019456:IPR011766; KEGG: apv:Apar_1328 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric YP_004373563.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); InterPro IPR006154:IPR015967:IPR006171:IPR000093; KEGG: apv:Apar_0117 recombination protein RecR; PFAM: TOPRIM domain-containing protein; Zinc finger C4-type, RecR; SMART: Toprim sub domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: recombination protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004373564.1 COGs: COG0718 conserved hypothetical protein; InterPro IPR004401; KEGG: ccu:Ccur_01590 conserved hypothetical protein TIGR00103; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein COLAER_01238; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family YP_004373565.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR003959:IPR012763; KEGG: apv:Apar_0115 DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; PRIAM: DNA-directed DNA polymerase; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004373566.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR020635:IPR002290:IPR000719:IPR017442; KEGG: apv:Apar_1340 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: uncharacterized protein; PFAM: Protein kinase domain YP_004373567.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253:IPR006162; KEGG: apv:Apar_1341 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF2662); FHA domain YP_004373568.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: apv:Apar_1342 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: FHA domain YP_004373569.1 COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR001932:IPR014045; KEGG: apv:Apar_1343 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: uncharacterized protein; PFAM: Protein phosphatase 2C YP_004373570.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001182:IPR005311:IPR001460; KEGG: apv:Apar_1344 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; cell cycle protein; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: uncharacterized protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; Cell cycle protein YP_004373571.1 COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR000719:IPR 017441:IPR008271:IPR017442; KEGG: apv:Apar_1345 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: uncharacterized protein; PFAM: Protein kinase domain; PASTA domain YP_004373572.1 COGs: COG3885 conserved hypothetical protein; InterPro IPR002733:IPR004183; KEGG: ele:Elen_1695 hypothetical protein; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: 3,4-dihydroxyphenylacetate 2,3-dioxygenase, AMMECR1 domain protein; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: uncharacterized protein, PH0010 family YP_004373573.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: dda:Dd703_2153 protein-N(pi)-phosphohistidine--sugar phosphotransferase; PFAM: type III effector Hrp-dependent outers; SPTR: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; PFAM: Protein of unknown function, DUF1537 YP_004373574.1 InterPro IPR004684; KEGG: cro:ROD_50561 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; SPTR: 2-keto-3-deoxygluconate permease; PFAM: 2-keto-3-deoxygluconate permease; TIGRFAM: 2-keto-3-deoxygluconate transporter; TC 2.A.10.1.1 YP_004373575.1 COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: bcl:ABC2085 transcriptional regulator; PFAM: sugar isomerase (SIS); SPTR: Predicted protein; PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_004373576.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR017583; KEGG: apv:Apar_0322 1-phosphofructokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family YP_004373577.1 InterPro IPR001647; KEGG: ele:Elen_0081 TetR family transcriptional regulator; PFAM: TetR family transcripitonal regulator; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family YP_004373578.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: ele:Elen_0080 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter YP_004373579.1 KEGG: ele:Elen_0079 hypothetical protein; SPTR: uncharacterized protein YP_004373580.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: efa:EF0438 hypothetical protein; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: AP endonuclease; PFAM: Xylose isomerase-like TIM barrel YP_004373581.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701:IPR001927; KEGG: lsl:LSL_1933 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: Sodium/galactoside symporter; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter YP_004373582.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR020904:IPR002198:IPR002347; KEGG: snt:SPT_0369 gluconate 5-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Gluconate 5-dehydrogenase; PFAM: short chain dehydrogenase YP_004373583.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: cac:CA_C2606 hypothetical protein; PFAM: Ribose/galactose isomerase; SPTR: uncharacterized protein; PFAM: Ribose-5-phosphate isomerase; Ribose/Galactose Isomerase YP_004373584.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: spp:SPP_0363 sugar binding transcriptional regulator RegR; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Sugar binding transcriptional regulator RegR; PFAM: Bacterial regulatory proteins, lacI family; family YP_004373585.1 COGs: COG5434 Endopygalactorunase; KEGG: pdi:BDI_2467 glycoside hydrolase family protein; SPTR: Glycoside hydrolase family 28; PFAM: Glycosyl hydrolases family 28 YP_004373586.1 KEGG: bth:BT_3685 hypothetical protein; SPTR: Licheninase; PFAM: Glycosyl hydrolases family 43 YP_004373587.1 KEGG: rec:RHECIAT_PC0000512 hypothetical protein; SPTR: uncharacterized protein YP_004373588.1 COGs: COG3507 Beta-xylosidase; InterPro IPR006710; KEGG: scl:sce4884 xylan 1,4-beta-xylosidase; PFAM: glycoside hydrolase family 43; PRIAM: Xylan 1,4-beta-xylosidase; SPTR: Xylan beta-1,4-xylosidase; PFAM: Glycosyl hydrolases family 43 YP_004373589.1 InterPro IPR010905; KEGG: pjd:Pjdr2_4134 glycosyl hydrolase family 88; PFAM: glycosyl hydrolase family 88; SPTR: Glycosyl hydrolase family 88; PFAM: Glycosyl Hydrolase Family 88 YP_004373590.1 KEGG: pth:PTH_1214 hypothetical protein; SPTR: uncharacterized protein YP_004373591.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: pct:PC1_3949 PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component YP_004373592.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: cro:ROD_38601 PTS system, sorbose-specific IIC component; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: PTS system, sorbose-specific IIC component; PFAM: PTS system sorbose-specific iic component YP_004373593.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: pct:PC1_3951 protein-N(pi)-phosphohistidine--sugar phosphotransferase; PFAM: PTS system sorbose subfamily IIB component; SPTR: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; PFAM: PTS system sorbose subfamily IIB component YP_004373594.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: cdl:CDR20291_0933 PTS system, IIa component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system, IIA component, mannose/fructose/sorbose family; PFAM: PTS system fructose IIA component YP_004373595.1 COGs: COG4289 conserved hypothetical protein; InterPro IPR016624; KEGG: enc:ECL_04350 hypothetical protein; PFAM: Uncharacterised conserved protein UCP014753; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2264) YP_004373598.1 KEGG: fma:FMG_1501 albumin-binding protein homolog-1; SPTR: uncharacterized protein YP_004373599.1 KEGG: oaa:100090938 hypothetical protein LOC100090938; SPTR: Hydrolase, alpha/beta fold family YP_004373600.1 COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sga:GALLO_0958 PTS system, fructose-specific IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component YP_004373601.1 COGs: COG1445 Phosphotransferase system fructose-specific component IIB; InterPro IPR013011:IPR003353; KEGG: sga:GALLO_0959 PTS system, fructose-specific IIB component; SPTR: uncharacterized protein; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, fructose-specific, IIB component; TC 4.A.2 YP_004373602.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterPro IPR013014:IPR003352:IPR006327; KEGG: sga:GALLO_0960 PTS system, fructose-specific IIC component; PFAM: phosphotransferase system EIIC; SPTR: Phosphotransferase system, EIIC; TIGRFAM: PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC component YP_004373603.1 COGs: COG0383 Alpha-mannosidase; InterPro IPR000602:IPR011682; KEGG: sga:GALLO_0961 glycosyl hydrolase; PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; SPTR: Glycosyl hydrolase family 38 N-terminal domain protein; PFAM: Glycosyl hydrolases family 38 C-terminal domain; Glycosyl hydrolases family 38 N-terminal domain; Alpha mannosidase, middle domain YP_004373604.1 COGs: COG3711 Transcriptional antiterminator; InterPro IPR002178:IPR013011:IPR011608; KEGG: cdf:CD2565 transcriptional antiterminator; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRD domain protein; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PRD domain protein; PFAM: HTH domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_004373605.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: lsg:lse_2614 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004373606.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lsg:lse_2612 PTS betaglucoside-specific enzyme IIC component , PFAM: phosphotransferase system EIIC; SPTR: uncharacterized protein; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: PTS system, lactose/cellobiose family IIC component YP_004373607.1 InterPro IPR005181; KEGG: ppe:PEPE_1762 hypothetical protein; PFAM: protein of unknown function DUF303 acetylesterase; SPTR: Sialate O-acetylesterase; PFAM: Domain of unknown function (DUF303) YP_004373608.1 COGs: COG2730 Endoglucanase; KEGG: llm:llmg_1321 hypothetical protein; PRIAM: Glucan 1,3-beta-glucosidase; SPTR: uncharacterized protein; PFAM: Cellulase (glycosyl hydrolase family 5) YP_004373609.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: llm:llmg_1322 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily YP_004373610.1 COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005:IPR020449; KEGG: llc:LACR_1288 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain YP_004373611.1 COGs: COG3507 Beta-xylosidase; InterPro IPR018247:IPR006710; KEGG: llc:LACR_1291 beta-xylosidase; PFAM: glycoside hydrolase family 43; PRIAM: Xylan 1,4-beta-xylosidase; SPTR: Beta-xylosidase; PFAM: Glycosyl hydrolases family 43 YP_004373613.1 KEGG: dya:Dyak_GE13051 GE13051 gene product from transcript GE13051-RA; SPTR: uncharacterized protein YP_004373614.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: bcl:ABC1731 glucokinase; PFAM: ROK family protein; SPTR: Glucokinase; PFAM: ROK family YP_004373615.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: sca:Sca_0223 haloacid dehalogenase-like hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004373616.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: cbe:Cbei_4841 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; Oxidoreductase domain; SPTR: Oxidoreductase, Gfo/Idh/MocA family; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_004373617.1 COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ere:EUBREC_2881 AP-endonuclease/AP-lyase; PFAM: Xylose isomerase domain-containing protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel YP_004373618.1 COGs: COG3664 Beta-xylosidase; InterPro IPR018060:IPR000005:IPR000514; KEGG: aoe:Clos_0056 AraC family transcriptional regulator; PFAM: glycoside hydrolase family 39; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Predicted protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; Glycosyl hydrolases family 39 YP_004373620.1 KEGG: eel:EUBELI_20453 hypothetical protein; SPTR: uncharacterized protein YP_004373621.1 KEGG: shi:Shel_06610 hypothetical protein; SPTR: uncharacterized protein YP_004373622.1 KEGG: shi:Shel_21970 hypothetical protein; SPTR: uncharacterized protein YP_004373623.1 COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: ppe:PEPE_0197 mannose-specific PTS system component IIC; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: uncharacterized protein; PFAM: PTS system sorbose-specific iic component YP_004373624.1 COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: bcl:ABC4073 PTS system, mannose-specific enzyme II, D component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: uncharacterized protein; PFAM: PTS system mannose/fructose/sorbose family IID component; TC 4.A.6 YP_004373625.1 COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: ljo:LJ0627 phosphoenolpyruvate-dependent sugar phosphotransferase system EIIAB, mannose specific; PFAM: PTS system sorbose subfamily IIB component; SPTR: uncharacterized protein; PFAM: PTS system sorbose subfamily IIB component YP_004373626.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347; KEGG: bcl:ABC4074 hypothetical protein; PFAM: sugar isomerase (SIS); PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: uncharacterized protein; PFAM: SIS domain YP_004373627.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: str:Sterm_3396 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: uncharacterized protein; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004373628.1 COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: bha:BH3323 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain-containing protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_004373629.1 COGs: COG2407 L-fucose isomerase and related protein; KEGG: cac:CA_C2610 L-fucose isomerase related protein; SPTR: L-fucose isomerase related protein; PFAM: L-fucose isomerase, C-terminal domain YP_004373630.1 KEGG: cac:CA_C2611 hypothetical protein; SPTR: uncharacterized protein YP_004373631.1 COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485:IPR006000; KEGG: ere:EUBREC_2559 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_004373632.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701:IPR001927; KEGG: ppe:PEPE_0185 Na+/xyloside symporter related transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Na+/xyloside symporter related transporter; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter YP_004373633.1 COGs: COG1501 Alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: ppe:PEPE_0184 alpha-xylosidase YicI; PFAM: glycoside hydrolase family 31; SPTR: Alpha-glucosidase, family 31 of glycosyl hydrolase; PFAM: Glycosyl hydrolases family 31 YP_004373634.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR019825:IPR001808:IPR000600; KEGG: bde:BDP_0576 NagC/XylR-type transciptional regulator; PFAM: ROK family protein; regulatory protein Crp; SPTR: uncharacterized protein; PFAM: ROK family; IclR helix-turn-helix domain YP_004373635.1 KEGG: blj:BLD_1885 hypothetical membrane protein; SPTR: Hypothetical membrane protein YP_004373636.1 COGs: COG4214 ABC-type xylose transport system permease component; InterPro IPR001851; KEGG: bde:BDP_0572 rbsC1 ribose transport system permease protein RbsC; PFAM: inner-membrane translocator; SPTR: Sugar ABC transporter, permease protein; PFAM: Branched-chain amino acid transport system / permease component YP_004373637.1 COGs: COG1129 ABC-type sugar transport system ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: bde:BDP_0571 rbsA1 ribose transport ATP-binding protein RbsA; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: RbsA1 Ribose transport ATP-binding protein rbsA; PFAM: ABC transporter YP_004373638.1 COGs: COG4213 ABC-type xylose transport system periplasmic component; InterPro IPR001761; KEGG: bde:BDP_0570 ABC transporter (substrate-binding protein); PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ABC transporter (Substrate-binding protein); PFAM: family YP_004373639.1 KEGG: shi:Shel_08110 hypothetical protein; SPTR: uncharacterized protein; PFAM: GIY-YIG catalytic domain YP_004373640.1 KEGG: shi:Shel_25980 hypothetical protein; SPTR: uncharacterized protein; manually curated; PFAM: Protein of unknown function (DUF2992) YP_004373641.1 COGs: COG1521 transcriptional regulator protein; InterPro IPR004619; KEGG: apv:Apar_0113 transcriptional acitvator, Baf family; PFAM: Bvg accessory factor; SPTR: uncharacterized protein; TIGRFAM: transcriptional activator, Baf family; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004373642.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489:IPR000550:IPR006390; KEGG: apv:Apar_0111 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: uncharacterized protein; TIGRFAM: dihydropteroate synthase; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: Pterin binding enzyme; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: dihydropteroate synthase; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004373643.1 COGs: COG0708 Exonuclease III; InterProIPR004808:IPR020847:IPR020848:IPR005135:IPR 000097; KEGG: apv:Apar_0110 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: uncharacterized protein; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004373644.1 COGs: COG4651 Kef-type K+ transport system predicted NAD-binding component; InterPro IPR003148:IPR006037:IPR006153; KEGG: chl:Chy400_3708 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: Sodium/hydrogen exchanger; PFAM: TrkA-N domain; TrkA-C domain; Sodium/hydrogen exchanger family YP_004373645.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR005835:IPR001451:IPR005882; KEGG: apv:Apar_0343 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004373646.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: apv:Apar_0342 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: uncharacterized protein; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004373647.1 COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR018171:IPR001328; KEGG: ccu:Ccur_03980 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004373648.1 COGs: COG3513 conserved hypothetical protein; InterPro IPR010145; KEGG: sak:SAK_1017 hypothetical protein; SPTR: CRISPR-associated protein, Csn1 family; TIGRFAM: CRISPR-associated protein, Csn1 family; TIGRFAM: CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI YP_004373649.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019855; KEGG: tde:TDE0328 CRISPR-associated Cas1 family protein; PFAM: protein of unknown function DUF48; SPTR: CRISPR-associated protein Cas1, NMENI subtype; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, subtype II/NMENI; CRISPR-associated endonuclease Cas1 YP_004373650.1 COGs: COG3512 conserved hypothetical protein; InterPro IPR019199:IPR021127; KEGG: fma:FMG_0060 hypothetical protein; PFAM: Virulence-associated protein D / CRISPR associated protein Cas2; SPTR: CRISPR-associated protein Cas2; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004373651.1 KEGG: tde:TDE0330 CRISPR-associated Csn2 family protein; SPTR: uncharacterized protein; PFAM: CRISPR-associated protein (Cas_Csn2); TIGRFAM: CRISPR type II-A/NMEMI-associated protein Csn2 YP_004373652.1 KEGG: ptm:GSPATT00001716001 hypothetical protein; SPTR: DNA or RNA helicases of superfamily II YP_004373653.1 KEGG: tet:TTHERM_00958720 hypothetical protein; SPTR: uncharacterized protein YP_004373654.1 KEGG: rsk:RSKD131_3583 TonB-dependent siderophore receptor precursor; SPTR: TonB-dependent siderophore receptor YP_004373655.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR017927:IPR012165:IPR001433:IPR019480; KEGG: apv:Apar_0338 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: uncharacterized protein; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004373656.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR006004:IPR000759; KEGG: apv:Apar_0337 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric YP_004373658.1 KEGG: eel:EUBELI_01147 cytidylate kinase; SPTR: uncharacterized protein YP_004373659.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: ele:Elen_1136 polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_004373660.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: cbe:Cbei_4171 polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_004373661.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR006311; KEGG: cbe:Cbei_4172 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004373662.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: afn:Acfer_0777 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter YP_004373663.1 COGs: COG1610 conserved hypothetical protein; InterPro IPR019004; KEGG: ele:Elen_0243 GatB/YqeY domain-containing protein; SPTR: uncharacterized protein; PFAM: Yqey-like protein YP_004373664.1 InterPro IPR000297; KEGG: ele:Elen_0014 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein; PFAM: PPIC-type PPIASE domain YP_004373665.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR001555:IPR002376:IPR004607; KEGG: apv:Apar_0035 phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004373666.1 COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733; KEGG: apv:Apar_0034 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004373667.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR017932:IPR005854:IPR000583:IPR000836; KEGG: apv:Apar_0033 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; SPTR: uncharacterized protein; TIGRFAM: amidophosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004373668.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR002772; KEGG: gym:GYMC10_2809 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Beta-glucosidase; PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain YP_004373669.1 COGs: COG1455 Phosphotransferase system cellobiose-specific component IIC; InterPro IPR004501:IPR003352; KEGG: lmc:Lm4b_00043 PTS system, cellobiose-specific IIC component; PFAM: phosphotransferase system EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system protein; TIGRFAM: PTS system, lactose/cellobiose family IIC subunit; PFAM: Phosphotransferase system, EIIC; TIGRFAM: phosphotransferase system, cellobiose specific, IIC component; PTS system, lactose/cellobiose family IIC component YP_004373670.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cbt:CLH_2695 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; IclR helix-turn-helix domain YP_004373671.1 COGs: COG3669 Alpha-L-fucosidase; InterPro IPR000933:IPR016286; KEGG: pru:PRU_1164 alpha-L-fucosidase family protein; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); SMART: glycoside hydrolase family 29 (alpha-L-fucosidase); SPTR: Alpha-L-fucosidase; PFAM: Alpha-L-fucosidase YP_004373672.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cbe:Cbei_0443 ROK family protein; PFAM: ROK family protein; SPTR: uncharacterized protein; PFAM: ROK family YP_004373673.1 COGs: COG0153 Galactokinase; InterProIPR000705:IPR006203:IPR019539:IPR006204:IPR 006206; KEGG: apv:Apar_0819 galactokinase; PFAM: GHMP kinase; Galactokinase galactose-binding domain; PRIAM: Galactokinase; SPTR: uncharacterized protein; PFAM: Galactokinase galactose-binding signature; GHMP kinases N terminal domain YP_004373674.1 COGs: COG4468 Galactose-1-phosphate uridyltransferase; InterPro IPR000766:IPR005849:IPR005850; KEGG: apv:Apar_0820 galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: uncharacterized protein; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 2 YP_004373675.1 InterPro IPR010540; KEGG: ele:Elen_1156 protein of unknown function DUF1113; PFAM: protein of unknown function DUF1113; SPTR: uncharacterized protein; PFAM: Protein of unknown function (DUF1113) YP_004373676.1 COGs: COG4509 conserved hypothetical protein; InterPro IPR005754; KEGG: apv:Apar_0032 sortase, SrtB family; PFAM: peptidase C60 sortase A and B; SPTR: uncharacterized protein; PFAM: Sortase family; TIGRFAM: sortase, SrtB family YP_004373677.1 COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: apv:Apar_0031 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004373678.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR011761:IPR005479:IPR005481:IPR005480:IPR 011607:IPR006275:IPR005483; KEGG: shi:Shel_13230 carbamoyl-phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004373679.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR017926:IPR002474:IPR000991:IPR006274:IPR 001317:IPR011702; KEGG: shi:Shel_13220 carbamoyl-phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: uncharacterized protein; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004373680.1 COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: apv:Apar_0030 phosphomethylpyrimidine kinase type-1; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: uncharacterized protein; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase YP_004373682.1 KEGG: apv:Apar_0029 hypothetical protein; SPTR: uncharacterized protein YP_004373683.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR003593:IPR003439:IPR017940:IPR017871:IPR 001140; KEGG: apv:Apar_0028 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter YP_004373684.1 InterPro IPR020084:IPR000086; KEGG: apv:Apar_0027 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: uncharacterized protein; PFAM: NUDIX domain YP_004373685.1 COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR011761:IPR020559:IPR020562:IPR020561:IPR 020560:IPR000115; KEGG: apv:Apar_0026 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: uncharacterized protein; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004373686.1 COGs: COG0104 Adenylosuccinate synthase; InterPro IPR001114:IPR018220; KEGG: apv:Apar_0025 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004373687.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR007694:IPR007693:IPR007692; KEGG: apv:Apar_0024 replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SPTR: uncharacterized protein; TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004373688.1 COGs: COG0359 Ribosomal protein L9; InterPro IPR020070:IPR020069:IPR020594; KEGG: shi:Shel_27890 ribosomal protein L9; PFAM: Ribosomal protein L9-like; SPTR: 50S ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004373689.1 KEGG: apv:Apar_0022 hypothetical protein; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2232) YP_004373690.1 COGs: COG0238 Ribosomal protein S18; InterPro IPR018275:IPR001648; KEGG: apv:Apar_0021 ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004373691.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: apv:Apar_0020 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004373692.1 COGs: COG0360 Ribosomal protein S6; InterPro IPR020814:IPR000529; KEGG: ele:Elen_0022 ribosomal protein S6; PFAM: Ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004373693.1 KEGG: apv:Apar_0018 hypothetical protein; SPTR: uncharacterized protein YP_004373694.1 COGs: COG2860 membrane protein; InterPro IPR005115; KEGG: apv:Apar_0017 protein of unknown function UPF0126; PFAM: Uncharacterised protein family UPF0126; SPTR: uncharacterized protein; PFAM: UPF0126 domain YP_004373695.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795:IPR004161:IPR000640:IPR005225:IPR 006298; KEGG: apv:Apar_0016 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: uncharacterized protein; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004373696.1 KEGG: apv:Apar_0015 hypothetical protein; SPTR: uncharacterized protein YP_004373697.1 InterPro IPR001623; KEGG: ccu:Ccur_00090 DnaJ-class molecular chaperone with C-terminal Zn finger domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ domain YP_004373698.1 COGs: COG4932 outer membrane protein; InterPro IPR008454; KEGG: ele:Elen_0909 Cna B domain protein; PFAM: Cna B domain protein; SPTR: Cna B domain protein; PFAM: Cna protein B-type domain YP_004373699.1 COGs: COG4509 conserved hypothetical protein; KEGG: ele:Elen_0908 hypothetical protein; SPTR: uncharacterized protein; PFAM: Sortase family YP_004373700.1 KEGG: mmi:MMAR_2656 PE-PGRS family protein, PE_PGRS50; SPTR: uncharacterized protein YP_004373701.1 InterPro IPR002109; KEGG: apv:Apar_0976 glutaredoxin; PFAM: glutaredoxin; SPTR: Glutaredoxin; PFAM: Glutaredoxin YP_004373702.1 KEGG: apv:Apar_1356 hypothetical protein; SPTR: uncharacterized protein YP_004373703.1 COGs: COG1199 Rad3-related DNA helicase; InterProIPR006055:IPR014001:IPR006555:IPR014013:IPR 013520:IPR006054; KEGG: apv:Apar_1359 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; DEAD-like helicase ; helicase c2; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family; DnaQ family exonuclease/DinG family helicase YP_004373704.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterProIPR011761:IPR000291:IPR011127:IPR011095:IPR 005905; KEGG: apv:Apar_1360 D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004373705.1 COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383:IPR007197; KEGG: apv:Apar_1361 radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase YP_004373706.1 KEGG: pol:Bpro_2585 PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein YP_004373707.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: apv:Apar_1362 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: uncharacterized protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_004373708.1 COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: apv:Apar_1363 cobyrinic acid ac-diamide synthase; SPTR: uncharacterized protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004373709.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682:IPR008162; KEGG: shi:Shel_28500 glucose-inhibited division protein B; PFAM: glucose inhibited division protein; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB YP_004373710.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: ccu:Ccur_14170 predicted RNA-binding protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: uncharacterized protein; PFAM: R3H domain YP_004373711.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001:IPR013308; KEGG: apv:Apar_1366 60 kDa inner membrane insertion protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: uncharacterized protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain YP_004373712.1 COGs: COG0759 conserved hypothetical protein; InterPro IPR002696; KEGG: dvl:Dvul_1918 hypothetical protein; PFAM: protein of unknown function DUF37; SPTR: UPF0161 protein COLSTE_02211; manually curated; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004373713.1 InterPro IPR020539:IPR000100; KEGG: apv:Apar_1368 ribonuclease P protein component; SPTR: uncharacterized protein; TIGRFAM: ribonuclease P protein component; manually curated; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004373714.1 InterPro IPR020939:IPR000271; KEGG: shi:Shel_28540 LSU ribosomal protein L34P; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type