-- dump date 20120504_142742 -- class Genbank::CDS -- table cds_note -- id note NP_702919.1 CE2P001, similar to PIR:T36739 percent identity: 30 in 408 aa NP_702920.1 CE2P002, similar to Swiss_Prot:Q44349 percent identity: 31 in 399 aa NP_702921.1 CE2P003, similar to PIR:B97616 percent identity: 34 in 125 aa NP_702922.1 CE2P004, similar to PIR:S45081 percent identity: 24 in 45 aa NP_702923.1 CE2P005, similar to PIR:S60675 percent identity: 47 in 454 aa NP_702924.1 CE2P006, similar to Swiss_Prot:P35882 percent identity: 60 in 392 aa NP_702925.1 CE2P007 NP_702926.1 CE2P008, similar to Swiss_Prot:Q9KA26 percent identity: 29 in 42 aa NP_702927.1 CE2P009 NP_702928.1 CE2P010 NP_702929.1 CE2P011, similar to PIR:B97616 percent identity: 34 in 111 aa NP_702930.1 CE2P012, similar to Swiss_Prot:P75147 percent identity: 26 in 58 aa NP_702931.1 CE2P013, similar to PIR:S60675 percent identity: 47 in 452 aa NP_702932.1 CE2P014, similar to PIR:B64689 percent identity: 34 in 226 aa NP_702933.1 CE2P015, similar to Swiss_Prot:P03835 percent identity: 29 in 282 aa NP_702934.1 CE3P001, similar to PIR:S60889 percent identity: 90 in 97 aa NP_702935.1 CE3P002, similar to PIR:S60890 percent identity: 89 in 298 aa NP_702936.1 CE3P003 NP_702937.1 CE3P004, similar to Swiss_Prot:Q9FDU7 percent identity: 42 in 201 aa NP_702938.1 CE3P005, similar to Swiss_Prot:P55184 percent identity: 38 in 218 aa NP_702939.1 CE3P006, similar to PIR:T35282 percent identity: 30 in 263 aa NP_702940.1 CE3P007, similar to PIR:T37006 percent identity: 60 in 111 aa NP_702941.1 CE3P008, similar to PIR:T34891 percent identity: 52 in 151 aa NP_702942.1 CE3P009, similar to PIR:S76704 percent identity: 37 in 153 aa NP_702943.1 CE3P010, similar to Swiss_Prot:Q10799 percent identity: 44 in 32 aa NP_702944.1 CE3P011, similar to PIR:JQ0803 percent identity: 47 in 254 aa NP_702945.1 CE3P012, similar to Swiss_Prot:P24202 percent identity: 41 in 282 aa NP_702946.1 CE3P013, similar to Swiss_Prot:Q44363 percent identity: 33 in 375 aa NP_702947.1 CE3P014, similar to PIR:JC6324 percent identity: 38 in 60 aa NP_702948.1 CE3P015, similar to PIR:C72285 percent identity: 32 in 258 aa NP_702949.1 CE3P016, similar to PIR:T36983 percent identity: 34 in 196 aa NP_702950.1 CE3P017, similar to PIR:S34451 percent identity: 59 in 234 aa NP_702951.1 CE3P018, similar to PIR:D82268 percent identity: 55 in 22 aa NP_702952.1 CE3P019, similar to PIR:T44701 percent identity: 34 in 189 aa NP_702953.1 CE3P020 NP_702954.1 CE3P021, similar to PIR:A69419 percent identity: 35 in 141 aa NP_702955.1 CE3P022, similar to Swiss_Prot:Q10864 percent identity: 52 in 91 aa NP_702956.1 CE3P023, similar to PIR:D70716 percent identity: 55 in 138 aa NP_702957.1 CE3P024, similar to Swiss_Prot:P53525 percent identity: 36 in 307 aa NP_702958.1 CE3P025 NP_702959.1 CE3P026, similar to Swiss_Prot:Q10864 percent identity: 62 in 103 aa NP_702960.1 CE3P027, similar to Swiss_Prot:Q10866 percent identity: 56 in 618 aa NP_702961.1 CE3P028, similar to Swiss_Prot:Q10517 percent identity: 43 in 238 aa NP_702962.1 CE3P029, similar to PIR:G87586 percent identity: 53 in 609 aa NP_702963.1 CE3P030, similar to PIR:S34451 percent identity: 59 in 234 aa NP_702964.1 CE3P031, similar to Swiss_Prot:P04130 percent identity: 51 in 183 aa NP_702965.1 CE3P032, similar to PIR:JQ1544 percent identity: 46 in 112 aa NP_702966.1 CE3P033, similar to PIR:T00007 percent identity: 33 in 45 aa NP_702967.1 CE3P034 NP_702968.1 CE3P035, similar to PIR:G89799 percent identity: 36 in 84 aa NP_702969.1 CE3P036, similar to Swiss_Prot:P35882 percent identity: 61 in 396 aa NP_702970.1 CE3P037, similar to PIR:S60889 percent identity: 72 in 32 aa NP_702971.1 CE3P038, similar to PIR:S60890 percent identity: 89 in 242 aa NP_702972.1 CE3P039, similar to PIR:S74567 percent identity: 34 in 47 aa NP_702973.1 CE3P040, similar to PIR:AD2570 percent identity: 34 in 126 aa NP_702974.1 CE3P041, similar to Swiss_Prot:P46167 percent identity: 36 in 33 aa NP_736611.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_736613.1 binds the polymerase to DNA and acts as a sliding clamp NP_736614.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_736615.1 similar to AF222789-10|AAF33696.1| percent identity: 39 in 188 aa NP_736616.1 negatively supercoils closed circular double-stranded DNA NP_736619.1 similar to X65467-3|CAA46462.1| percent identity: 35 in 113 aa NP_736620.1 similar to Z74025-13|CAA98411.1| percent identity: 55 in 627 aa NP_736624.1 similar to Z95210-12|CAB08500.1| percent identity: 28 in 65 aa NP_736625.1 negatively supercoils closed circular double-stranded DNA NP_736626.1 similar to AL357152-9|CAB92992.1| percent identity: 28 in 105 aa NP_736627.1 similar to AX066773-1|CAC26614.1| percent identity: 44 in 530 aa NP_736628.1 similar to AE007169-5|AAK48039.1| percent identity: 33 in 375 aa NP_736629.1 similar to AL132824-22|CAB60176.1| percent identity: 45 in 319 aa NP_736630.1 similar to AL132824-23|CAB60177.1| percent identity: 56 in 335 aa NP_736631.1 similar to AL132824-24|CAB60178.1| percent identity: 63 in 252 aa NP_736633.1 similar to AF058285-1|AAC77368.1| percent identity: 40 in 465 aa NP_736634.1 similar to Z46523-1|CAA86569.1| percent identity: 35 in 180 aa NP_736635.1 similar to M86824-3|AAA25637.1| percent identity: 25 in 381 aa NP_736636.1 similar to AP003587-233|BAB73650.1| percent identity: 25 in 350 aa NP_736637.1 similar to AL627269-43|CAD08226.1| percent identity: 25 in 135 aa NP_736639.1 similar to AL583917-10|CAC29519.1| percent identity: 76 in 175 aa NP_736640.1 similar to AE006254-9|AAK04268.1| percent identity: 32 in 206 aa NP_736641.2 integral membrane protein involved in inhibition of the Z-ring formation NP_736643.1 similar to AL079308-18|CAB45215.1| percent identity: 37 in 644 aa NP_736644.1 similar to Z80233-12|CAB02434.1| percent identity: 33 in 499 aa NP_736645.1 similar to AL079356-13|CAB45623.1| percent identity: 35 in 473 aa NP_736646.1 similar to AL583917-17|CAC29527.1| percent identity: 45 in 441 aa NP_736647.1 similar to AE006916-7|AAK44243.1| percent identity: 45 in 429 aa NP_736648.1 similar to AE007565-3|AAK78484.1| percent identity: 26 in 153 aa NP_736649.1 similar to AL079308-13|CAB45210.1| percent identity: 24 in 284 aa NP_736651.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_736653.1 similar to AF164956-27|AAG00293.1| percent identity: 29 in 158 aa NP_736655.1 similar to AF164956-20|AAG00286.1| percent identity: 91 in 141 aa NP_736658.1 similar to AE005738-1|AAK22605.1| percent identity: 49 in 652 aa NP_736659.1 similar to AE005738-2|AAK22606.1| percent identity: 29 in 396 aa NP_736660.1 similar to AE006191-1|AAK03625.1| percent identity: 21 in 1032 aa NP_736661.1 similar to AJ420072-13|CAD12217.1| percent identity: 94 in 57 aa NP_736662.1 similar to AF164956-9|AAG00276.1| percent identity: 91 in 180 aa NP_736663.1 similar to AX065083-1|CAC25781.1| percent identity: 77 in 337 aa NP_736664.1 similar to AP003135-8|BAB42846.1| percent identity: 35 in 95 aa NP_736665.1 similar to AE005951-11|AAK24827.1| percent identity: 35 in 180 aa NP_736667.1 similar to AL133424-4|CAB62749.1| percent identity: 57 in 85 aa NP_736668.1 similar to AL109962-14|CAB53132.1| percent identity: 49 in 138 aa NP_736670.1 transports degraded pectin products into the bacterial cell NP_736671.1 similar to Z93767-14|CAB07788.1| percent identity: 29 in 305 aa NP_736673.1 similar to AP003599-86|BAB76963.1| percent identity: 38 in 205 aa NP_736674.1 similar to AL353832-28|CAB88834.1| percent identity: 28 in 144 aa NP_736675.1 similar to AL031013-9|CAA19781.1| percent identity: 28 in 398 aa NP_736679.1 similar to AE002052-6|AAF11741.1| percent identity: 27 in 248 aa NP_736682.1 similar to M55161-1|AAA24039.1| percent identity: 45 in 707 aa NP_736683.1 similar to AP003599-6|BAB76883.1| percent identity: 32 in 455 aa NP_736685.1 similar to AX066987-1|CAC26721.1| percent identity: 85 in 78 aa NP_736687.1 similar to AX066999-1|CAC26727.1| percent identity: 78 in 575 aa NP_736688.1 similar to AL590507-9|CAC36370.1| percent identity: 33 in 333 aa NP_736689.1 similar to U96338-1|AAA75634.2| percent identity: 55 in 490 aa NP_736690.1 similar to AL627270-196|CAD01823.1| percent identity: 25 in 416 aa NP_736692.1 similar to AX065995-1|CAC26237.1| percent identity: 80 in 478 aa NP_736694.1 similar to AX065017-1|CAC25748.1| percent identity: 74 in 120 aa NP_736697.1 similar to Z95584-15|CAB09036.1| percent identity: 27 in 321 aa NP_736699.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine NP_736700.1 similar to D85415-6|BAA12809.1| percent identity: 31 in 76 aa NP_736702.1 similar to AY045873-1|AAK76547.1| percent identity: 40 in 286 aa NP_736703.1 similar to AX066617-1|CAC26536.1| percent identity: 69 in 314 aa NP_736704.1 similar to AX066615-1|CAC26535.1| percent identity: 79 in 300 aa NP_736705.1 similar to X52480-5|CAA36723.1| percent identity: 35 in 107 aa NP_736708.1 similar to AL096884-34|CAB51457.1| percent identity: 26 in 393 aa NP_736709.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile NP_736711.1 similar to AX064025-1|CAC25253.1| percent identity: 75 in 1172 aa NP_736712.1 similar to AX067089-1|CAC26772.1| percent identity: 65 in 312 aa NP_736714.1 similar to AE005761-4|AAK22832.1| percent identity: 26 in 280 aa NP_736715.1 similar to AE006151-7|AAK03188.1| percent identity: 35 in 519 aa NP_736716.1 similar to AX065867-1|CAC26173.1| percent identity: 74 in 455 aa NP_736717.1 similar to AL096811-8|CAB46785.1| percent identity: 43 in 109 aa NP_736722.1 similar to AL591793-89|CAC47784.1| percent identity: 35 in 168 aa NP_736725.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_736726.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_736727.1 similar to AE008797-3|AAL21079.1| percent identity: 29 in 401 aa NP_736729.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair NP_736731.1 similar to AP001518-120|BAB07008.1| percent identity: 41 in 170 aa NP_736733.1 similar to Z77162-11|CAB00946.1| percent identity: 29 in 323 aa NP_736734.1 similar to AX066263-1|CAC26370.1| percent identity: 82 in 422 aa NP_736739.1 similar to AX065291-1|CAC25885.1| percent identity: 78 in 477 aa NP_736743.1 similar to AL096823-10|CAB46965.1| percent identity: 33 in 398 aa NP_736744.1 similar to AF152397-1|AAD38170.1| percent identity: 31 in 240 aa NP_736745.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_736747.1 similar to AL592292-7|CAC42843.1| percent identity: 33 in 534 aa NP_736748.1 similar to AL591789-170|CAC46677.1| percent identity: 30 in 369 aa NP_736749.1 similar to AX064231-1|CAC25356.1| percent identity: 83 in 260 aa NP_736751.1 similar to AJ414156-170|CAC92624.1| percent identity: 35 in 796 aa NP_736752.1 similar to AX065309-1|CAC25894.1| percent identity: 73 in 206 aa NP_736754.1 similar to AL591784-274|CAC45354.1| percent identity: 42 in 172 aa NP_736755.1 similar to AX063725-1|CAC25103.1| percent identity: 29 in 220 aa NP_736756.1 similar to AL646061-20|CAD14491.1| percent identity: 34 in 69 aa NP_736757.1 similar to AX066283-1|CAC26380.1| percent identity: 77 in 283 aa NP_736759.1 similar to AB011413-6|BAA32135.1| percent identity: 54 in 346 aa NP_736761.1 similar to SwissProt:P80407 percent identity: 38 in 29 aa NP_736762.1 similar to AE003904-7|AAF83386.1| percent identity: 34 in 681 aa NP_736768.1 similar to D85230-3|BAA12741.1| percent identity: 53 in 1495 aa NP_736769.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_736770.1 similar to AL583943-15|CAC32297.1| percent identity: 43 in 494 aa NP_736771.1 similar to AX065349-1|CAC25914.1| percent identity: 76 in 1148 aa NP_736772.1 similar to Z80343-25|CAB02471.1| percent identity: 35 in 656 aa NP_736773.1 similar to AX064581-1|CAC25530.1| percent identity: 88 in 253 aa NP_736774.1 similar to AX064567-1|CAC25523.1| percent identity: 92 in 487 aa NP_736775.1 similar to AF162656-1|AAD45530.1| percent identity: 26 in 302 aa NP_736776.1 similar to AL022121-105|CAA18078.1| percent identity: 42 in 209 aa NP_736777.1 similar to AL049727-10|CAB41556.1| percent identity: 36 in 217 aa NP_736778.1 similar to AL022121-107|CAA18080.1| percent identity: 52 in 272 aa NP_736782.1 similar to AE007183-5|AAK48262.1| percent identity: 52 in 144 aa NP_736784.1 similar to AL031317-43|CAA20421.1| percent identity: 41 in 202 aa NP_736785.1 similar to Z80343-15|CAB02461.1| percent identity: 60 in 297 aa NP_736787.1 similar to AE007182-19|AAK48255.1| percent identity: 75 in 264 aa NP_736788.1 similar to AX067071-1|CAC26763.1| percent identity: 88 in 298 aa NP_736789.1 similar to AX064369-1|CAC25425.1| percent identity: 72 in 391 aa NP_736790.1 similar to AE007182-15|AAK48251.1| percent identity: 50 in 318 aa NP_736791.1 similar to AE007169-1|AAK48035.1| percent identity: 40 in 97 aa NP_736793.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase NP_736794.1 similar to AX064457-1|CAC25469.1| percent identity: 73 in 152 aa NP_736795.1 similar to AX064467-1|CAC25474.1| percent identity: 66 in 156 aa NP_736796.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_736797.1 similar to AE004728-2|AAG06416.1| percent identity: 33 in 383 aa NP_736798.1 similar to AX067075-1|CAC26765.1| percent identity: 74 in 271 aa NP_736799.1 similar to AL078610-34|CAB44407.1| percent identity: 35 in 254 aa NP_736800.1 similar to AF128444-2|AAD21202.1| percent identity: 31 in 85 aa NP_736801.1 similar to AL591790-292|CAC47078.1| percent identity: 40 in 280 aa NP_736802.1 similar to AE001965-12|AAF10738.1| percent identity: 33 in 133 aa NP_736803.1 similar to AL034355-11|CAA22216.1| percent identity: 49 in 336 aa NP_736804.1 similar to AX066933-1|CAC26694.1| percent identity: 79 in 536 aa NP_736805.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate NP_736807.1 similar to AL583925-127|CAC31991.1| percent identity: 54 in 152 aa NP_736810.1 similar to AE007840-5|AAK81361.1| percent identity: 33 in 798 aa NP_736811.1 similar to AP003134-179|BAB42731.1| percent identity: 43 in 391 aa NP_736812.1 similar to AE001685-1|AAD19182.1| percent identity: 25 in 200 aa NP_736813.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu NP_736814.1 similar to AP003599-38|BAB76915.1| percent identity: 31 in 437 aa NP_736816.1 similar to AF303831-1|AAG30904.1| percent identity: 33 in 282 aa NP_736817.1 similar to AX064167-1|CAC25324.1| percent identity: 83 in 425 aa NP_736819.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_736820.1 similar to AF151381-1|AAD34031.2| percent identity: 52 in 99 aa NP_736821.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_736822.1 similar to AP003363-264|BAB58053.1| percent identity: 31 in 251 aa NP_736823.1 similar to AL023596-16|CAA19164.1| percent identity: 56 in 408 aa NP_736824.1 3'-5' exonuclease of DNA polymerase III NP_736826.1 similar to X70959-1|CAA50295.1| percent identity: 91 in 581 aa NP_736829.1 similar to AL133278-28|CAB61939.1| percent identity: 27 in 274 aa NP_736830.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. NP_736831.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_736832.1 similar to AE001111-5|AAB91271.1| percent identity: 25 in 301 aa NP_736833.2 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription NP_736834.1 similar to AX066107-1|CAC26293.1| percent identity: 88 in 516 aa NP_736836.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_736837.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_736838.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone NP_736840.1 similar to AJ248285-63|CAB49619.1| percent identity: 33 in 83 aa NP_736841.1 similar to Z93932-7|CAB07906.1| percent identity: 29 in 113 aa NP_736843.1 similar to Z99494-27|CAB16701.1| percent identity: 40 in 223 aa NP_736844.1 similar to AL049497-15|CAB39869.1| percent identity: 41 in 453 aa NP_736846.1 similar to AE008849-13|AAL22119.1| percent identity: 39 in 385 aa NP_736847.1 similar to AE004211-5|AAF94472.1| percent identity: 21 in 465 aa NP_736850.1 similar to AL646078-169|CAD17629.1| percent identity: 42 in 430 aa NP_736854.1 similar to AY033500-1|AAK51146.1| percent identity: 48 in 75 aa NP_736855.1 similar to X69104-2|CAA48850.1| percent identity: 88 in 298 aa NP_736856.1 similar to AL031155-6|CAA20069.1| percent identity: 44 in 97 aa NP_736857.1 similar to M14365-4|AAA88437.1| percent identity: 36 in 63 aa NP_736858.1 similar to X69104-2|CAA48850.1| percent identity: 89 in 298 aa NP_736859.1 similar to AE007150-15|AAK47773.1| percent identity: 32 in 387 aa NP_736864.1 similar to AF435074-1|AAL31536.1| percent identity: 78 in 56 aa NP_736865.1 similar to AF052055-1|AAC05832.1| percent identity: 48 in 121 aa NP_736866.1 similar to D17429-1|BAA04250.1| percent identity: 54 in 280 aa NP_736867.1 similar to AE001564-11|AAD07001.1| percent identity: 27 in 791 aa NP_736868.1 similar to U67562-19|AAB99219.1| percent identity: 22 in 401 aa NP_736869.1 similar to AE006191-1|AAK03625.1| percent identity: 25 in 1075 aa NP_736870.1 similar to AF036242-2|AAD38302.1| percent identity: 25 in 222 aa NP_736871.1 similar to AB004563-5|BAB78769.1| percent identity: 43 in 205 aa NP_736872.1 similar to X55075-3|CAA38902.1| percent identity: 27 in 109 aa NP_736873.1 similar to Z80225-18|CAB02366.1| percent identity: 41 in 100 aa NP_736875.1 similar to AL591982-197|CAD00294.1| percent identity: 35 in 137 aa NP_736882.1 similar to U65658-1|AAB05880.1| percent identity: 24 in 330 aa NP_736884.1 similar to AE007256-11|AAK65346.1| percent identity: 30 in 70 aa NP_736885.1 similar to AL022121-31|CAA18004.1| percent identity: 47 in 774 aa NP_736886.1 similar to AJ414145-167|CAC89846.1| percent identity: 39 in 201 aa NP_736888.1 similar to AL591983-180|CAD00579.1| percent identity: 42 in 227 aa NP_736889.1 similar to AP003597-134|BAB76425.1| percent identity: 31 in 359 aa NP_736891.1 similar to AE000724-9|AAC07161.1| percent identity: 47 in 631 aa NP_736893.1 similar to AE007176-1|AAK48150.1| percent identity: 57 in 107 aa NP_736894.1 similar to AL079353-10|CAB45556.1| percent identity: 84 in 49 aa NP_736895.1 similar to AL079353-9|CAB45555.1| percent identity: 63 in 151 aa NP_736897.1 similar to AF293334-1|AAK58838.1| percent identity: 97 in 227 aa NP_736899.1 similar to AL583925-21|CAC31817.1| percent identity: 66 in 240 aa NP_736901.1 similar to AL022121-21|CAA17994.1| percent identity: 42 in 217 aa NP_736902.1 similar to AF322256-34|AAL15613.1| percent identity: 35 in 396 aa NP_736903.1 similar to AX065881-1|CAC26180.1| percent identity: 56 in 305 aa NP_736904.1 similar to AE001940-6|AAF10446.1| percent identity: 23 in 150 aa NP_736906.1 similar to AJ010584-1|CAB55344.1| percent identity: 31 in 273 aa NP_736908.1 similar to AL035636-18|CAB38493.1| percent identity: 55 in 348 aa NP_736909.1 similar to AL035636-17|CAB38492.1| percent identity: 31 in 262 aa NP_736910.1 similar to AL022121-6|CAA17979.1| percent identity: 36 in 177 aa NP_736913.1 similar to AE005892-8|AAK24177.1| percent identity: 33 in 95 aa NP_736915.1 similar to AL035636-12|CAB38487.1| percent identity: 47 in 805 aa NP_736916.1 similar to AX066179-1|CAC26328.1| percent identity: 83 in 67 aa NP_736917.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_736920.1 similar to AE007009-7|AAK45622.1| percent identity: 36 in 529 aa NP_736921.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_736922.1 similar to AL596162-29|CAC44608.1| percent identity: 39 in 263 aa NP_736927.1 similar to AP002999-43|BAB49358.1| percent identity: 33 in 252 aa NP_736928.1 similar to AE005951-11|AAK24827.1| percent identity: 36 in 181 aa NP_736929.1 similar to AE001863-93|AAF12471.1| percent identity: 52 in 483 aa NP_736931.1 similar to AP001509-40|BAB04321.1| percent identity: 30 in 663 aa NP_736932.1 similar to Y13917-10|CAA74218.1| percent identity: 40 in 258 aa NP_736933.1 similar to U29084-2|AAB09614.1| percent identity: 40 in 286 aa NP_736934.1 similar to U18992-1|AAB04679.1| percent identity: 39 in 426 aa NP_736935.1 similar to U10895-2|AAA85138.1| percent identity: 53 in 397 aa NP_736936.1 similar to Z48178-2|CAA88202.1| percent identity: 46 in 484 aa NP_736938.1 similar to AE008751-16|AAL20116.1| percent identity: 41 in 287 aa NP_736939.1 similar to U08606-1|AAA80156.1| percent identity: 29 in 601 aa NP_736940.1 similar to AX065615-1|CAC26047.1| percent identity: 90 in 368 aa NP_736941.1 similar to AX066545-1|CAC26500.1| percent identity: 88 in 211 aa NP_736943.1 similar to AE001727-6|AAD35594.1| percent identity: 49 in 312 aa NP_736945.1 similar to AX066673-1|CAC26564.1| percent identity: 83 in 257 aa NP_736946.1 similar to AE006021-10|AAK25594.1| percent identity: 24 in 311 aa NP_736947.1 similar to AE007549-13|AAK78333.1| percent identity: 28 in 550 aa NP_736948.1 similar to AL583923-54|CAC30683.1| percent identity: 54 in 354 aa NP_736949.1 similar to AE004394-5|AAF96545.1| percent identity: 45 in 534 aa NP_736950.1 similar to AP003597-36|BAB76327.1| percent identity: 25 in 312 aa NP_736952.1 similar to AF071085-7|AAC35920.1| percent identity: 65 in 287 aa NP_736953.1 similar to AX065317-1|CAC25898.1| percent identity: 77 in 456 aa NP_736954.1 similar to AF105113-5|AAD19915.1| percent identity: 60 in 342 aa NP_736956.1 similar to AJ420072-16|CAD12220.1| percent identity: 77 in 464 aa NP_736958.1 similar to AJ391261-3|CAB72032.1| percent identity: 43 in 205 aa NP_736960.1 similar to AE002558-2|AAF42402.1| percent identity: 38 in 342 aa NP_736962.1 similar to AE007172-8|AAK48093.1| percent identity: 38 in 396 aa NP_736963.1 similar to AX065779-1|CAC26129.1| percent identity: 72 in 457 aa NP_736964.1 similar to AL162753-195|CAB83870.1| percent identity: 33 in 673 aa NP_736965.1 similar to AE005390-1|AAG56654.1| percent identity: 47 in 100 aa NP_736966.1 similar to AE007185-2|AAK48277.1| percent identity: 26 in 366 aa NP_736967.1 similar to AP002554-106|BAB34560.1| percent identity: 30 in 319 aa NP_736968.1 similar to D21242-7|BAA04776.1| percent identity: 34 in 126 aa NP_736970.1 similar to U10927-24|AAA64643.1| percent identity: 34 in 564 aa NP_736971.1 similar to AF236052-10|AAF72959.1| percent identity: 27 in 325 aa NP_736972.1 similar to U50396-15|AAC45865.1| percent identity: 34 in 283 aa NP_736973.1 similar to AP003186-246|BAB80181.1| percent identity: 22 in 368 aa NP_736974.1 similar to X69104-1|CAA48849.1| percent identity: 84 in 58 aa NP_736975.1 similar to PIR:S60889 percent identity: 86 in 81 aa NP_736976.1 similar to AL031155-5|CAA20068.1| percent identity: 38 in 190 aa NP_736977.1 similar to AE009417-3|AAL45688.1| percent identity: 27 in 486 aa NP_736978.1 similar to AE000081-9|AAB91740.1| percent identity: 27 in 249 aa NP_736979.1 similar to X69104-2|CAA48850.1| percent identity: 87 in 117 aa NP_736981.1 similar to PIR:S60889 percent identity: 82 in 97 aa NP_736982.1 similar to PIR:S60890 percent identity: 84 in 95 aa NP_736983.1 similar to PIR:T34886 percent identity: 40 in 330 aa NP_736984.1 similar to PIR:S60890 percent identity: 92 in 204 aa NP_736985.1 similar to AY033500-1|AAK51146.1| percent identity: 57 in 102 aa NP_736986.1 similar to X69104-2|CAA48850.1| percent identity: 89 in 298 aa NP_736987.1 similar to AE007150-15|AAK47773.1| percent identity: 32 in 387 aa NP_736989.1 similar to S73325-1|AAC60479.1| percent identity: 30 in 262 aa NP_736990.1 similar to AE000823-9|AAB84886.1| percent identity: 41 in 307 aa NP_736991.1 similar to D14156-2|BAA03192.1| percent identity: 62 in 422 aa NP_736993.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component NP_736994.1 similar to AL096884-27|CAB51450.1| percent identity: 47 in 159 aa NP_736995.1 similar to AL021933-8|CAA17420.1| percent identity: 57 in 475 aa NP_736996.1 similar to AX113264-1|CAC37852.1| percent identity: 84 in 257 aa NP_736997.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_736998.1 catalyzes the reversible formation of fumarate and ubiquinol from succinate and ubiquinone NP_737000.1 similar to M55524-5|AAA25961.1| percent identity: 26 in 233 aa NP_737001.1 similar to AE005854-5|AAK23772.1| percent identity: 27 in 375 aa NP_737002.1 similar to AL355753-5|CAB90887.1| percent identity: 27 in 294 aa NP_737003.1 similar to AL021933-16|CAA17428.1| percent identity: 42 in 456 aa NP_737008.1 similar to AL353870-23|CAB89031.1| percent identity: 39 in 525 aa NP_737009.1 similar to AE006190-9|AAK03624.1| percent identity: 31 in 281 aa NP_737010.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_737011.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate NP_737012.1 similar to AJ309011-1|CAC84393.1| percent identity: 46 in 486 aa NP_737013.1 similar to AL591782-106|CAC41493.1| percent identity: 63 in 55 aa NP_737014.1 similar to AL133220-30|CAB61730.1| percent identity: 34 in 391 aa NP_737016.1 similar to AP003364-153|BAB58249.1| percent identity: 41 in 97 aa NP_737017.1 similar to Z74410-20|CAA98939.1| percent identity: 47 in 748 aa NP_737023.1 similar to X81894-2|CAA57483.1| percent identity: 29 in 380 aa NP_737024.1 similar to AJ420072-16|CAD12220.1| percent identity: 77 in 464 aa NP_737027.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_737031.1 activates fatty acids by binding to coenzyme A NP_737032.1 similar to AJ302072-1|CAC83495.1| percent identity: 35 in 408 aa NP_737033.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_737034.1 similar to AL160331-2|CAB77323.1| percent identity: 41 in 398 aa NP_737035.1 similar to AF123314-2|AAG43239.1| percent identity: 92 in 232 aa NP_737037.1 similar to AE006952-10|AAK44738.1| percent identity: 43 in 256 aa NP_737038.1 similar to AX064781-1|CAC25630.1| percent identity: 91 in 309 aa NP_737040.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_737044.1 similar to AX063879-1|CAC25181.1| percent identity: 79 in 353 aa NP_737045.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_737046.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_737048.1 similar to AE004833-9|AAG07558.1| percent identity: 52 in 180 aa NP_737049.1 similar to D85415-10|BAB62046.1| percent identity: 25 in 257 aa NP_737050.1 similar to AL445963-23|CAC14378.1| percent identity: 37 in 450 aa NP_737051.1 similar to AE004462-4|AAG03631.1| percent identity: 41 in 622 aa NP_737052.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_737053.1 catalyzes the NAD-dependent formation of 3-dehydroquinate and 3-dehydroshikimate from quinate and shikimate; oxidation of quinate is about 3 times more efficient NP_737054.1 similar to AF132735-7|AAF61311.1| percent identity: 21 in 275 aa NP_737056.1 similar to AP002551-165|BAB33836.1| percent identity: 39 in 338 aa NP_737057.1 similar to AX066789-1|CAC26622.1| percent identity: 78 in 524 aa NP_737058.1 similar to AE006182-4|AAK03541.1| percent identity: 31 in 316 aa NP_737060.1 similar to AX064537-1|CAC25508.1| percent identity: 83 in 594 aa NP_737061.1 similar to D90902-10|BAA16962.1| percent identity: 46 in 358 aa NP_737063.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_737067.1 similar to AX066995-1|CAC26725.1| percent identity: 67 in 871 aa NP_737068.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_737069.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX NP_737070.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_737071.1 similar to AX064923-1|CAC25701.1| percent identity: 81 in 202 aa NP_737072.1 similar to AX066163-1|CAC26320.1| percent identity: 76 in 207 aa NP_737073.1 similar to U00018-4|AAA17226.1| percent identity: 53 in 248 aa NP_737074.1 similar to AE006954-13|AAK44773.1| percent identity: 52 in 533 aa NP_737075.1 similar to U00018-1|AAA17249.1| percent identity: 43 in 354 aa NP_737076.1 similar to AL445066-179|CAC12237.1| percent identity: 32 in 92 aa NP_737079.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_737081.1 similar to AE008803-13|AAL21206.1| percent identity: 29 in 388 aa NP_737082.1 similar to AE004713-1|AAG06252.1| percent identity: 31 in 132 aa NP_737084.1 similar to AL132644-30|CAB59461.1| percent identity: 56 in 384 aa NP_737085.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_737086.1 similar to D90909-80|BAA17842.1| percent identity: 27 in 86 aa NP_737087.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate NP_737088.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis NP_737089.1 similar to AL583925-4|CAC31787.1| percent identity: 36 in 138 aa NP_737090.1 similar to AY045961-1|AAK76635.1| percent identity: 30 in 381 aa NP_737091.2 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_737092.1 similar to AX066663-1|CAC26559.1| percent identity: 75 in 417 aa NP_737093.1 similar to AX066675-1|CAC26565.1| percent identity: 82 in 350 aa NP_737094.1 similar to SwissProt:Q9TU03 percent identity: 35 in 40 aa NP_737095.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_737096.1 Modulates Rho-dependent transcription termination NP_737097.2 binds directly to 23S ribosomal RNA NP_737099.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_737100.1 similar to AL646085-6|CAD18615.1| percent identity: 42 in 177 aa NP_737101.1 similar to AL021529-11|CAA16443.1| percent identity: 34 in 147 aa NP_737102.1 similar to AE001863-150|AAF12427.1| percent identity: 38 in 461 aa NP_737103.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_737104.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_737107.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_737108.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_737110.2 similar to AF024666-23|AAG03374.1| percent identity: 84 in 405 aa NP_737111.1 similar to AE000081-9|AAB91740.1| percent identity: 27 in 249 aa NP_737112.1 similar to AE009417-3|AAL45688.1| percent identity: 29 in 419 aa NP_737116.1 similar to AL021841-25|CAA17099.1| percent identity: 31 in 193 aa NP_737117.1 similar to X69104-1|CAA48849.1| percent identity: 78 in 102 aa NP_737118.1 similar to X69104-2|CAA48850.1| percent identity: 89 in 298 aa NP_737119.1 similar to AE007150-15|AAK47773.1| percent identity: 32 in 387 aa NP_737120.1 similar to AL023861-11|CAA19603.1| percent identity: 41 in 166 aa NP_737121.1 similar to AF024666-31|AAG03382.1| percent identity: 85 in 381 aa NP_737122.1 similar to AP002997-302|BAB48963.1| percent identity: 31 in 254 aa NP_737123.1 similar to AL035500-12|CAB36681.1| percent identity: 29 in 222 aa NP_737124.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_737125.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_737126.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_737127.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_737129.1 similar to AL121600-6|CAB56726.1| percent identity: 44 in 314 aa NP_737130.1 similar to AE009010-7|AAL41417.1| percent identity: 47 in 498 aa NP_737131.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_737132.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_737133.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_737134.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_737135.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_737136.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_737137.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_737138.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_737139.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_737140.1 one of the stabilizing components for the large ribosomal subunit NP_737141.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_737143.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_737144.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_737145.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_737147.1 similar to AE006356-7|AAK05341.1| percent identity: 52 in 246 aa NP_737148.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_737150.1 similar to AX065595-1|CAC26037.1| percent identity: 85 in 757 aa NP_737152.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_737154.1 similar to AL357591-15|CAB93444.1| percent identity: 49 in 563 aa NP_737155.1 similar to AX066849-1|CAC26652.1| percent identity: 70 in 371 aa NP_737158.1 similar to AE007546-2|AAK78296.1| percent identity: 35 in 127 aa NP_737159.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_737160.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_737161.1 binds 5S rRNA along with protein L5 and L25 NP_737162.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_737163.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_737164.1 similar to X17524-9|CAA35566.1| percent identity: 56 in 92 aa NP_737165.1 similar to AX065837-1|CAC26158.1| percent identity: 82 in 495 aa NP_737167.1 similar to AX065551-1|CAC26015.1| percent identity: 81 in 422 aa NP_737168.1 similar to AX065549-1|CAC26014.1| percent identity: 87 in 106 aa NP_737169.1 similar to AX066507-1|CAC26481.1| percent identity: 84 in 246 aa NP_737170.1 similar to AX064955-1|CAC25717.1| percent identity: 88 in 627 aa NP_737171.1 similar to AX064957-1|CAC25718.1| percent identity: 85 in 365 aa NP_737172.1 similar to AX065653-1|CAC26066.1| percent identity: 81 in 431 aa NP_737173.1 similar to AX065081-1|CAC25780.1| percent identity: 74 in 254 aa NP_737174.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_737175.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_737176.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_737178.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_737179.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_737180.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_737181.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_737182.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_737183.1 is a component of the macrolide binding site in the peptidyl transferase center NP_737184.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_737188.1 similar to AE007159-14|AAK47895.1| percent identity: 34 in 423 aa NP_737190.1 similar to AL031231-20|CAA20269.1| percent identity: 36 in 1180 aa NP_737193.1 similar to AX074038-1|CAC28445.1| percent identity: 34 in 92 aa NP_737195.1 similar to AF159510-8|AAK64303.1| percent identity: 65 in 289 aa NP_737196.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_737197.1 forms a direct contact with the tRNA during translation NP_737198.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_737202.1 similar to AL583918-51|CAC29878.1| percent identity: 44 in 254 aa NP_737203.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_737204.1 similar to AL583918-56|CAC29885.1| percent identity: 50 in 156 aa NP_737205.1 similar to AX066613-1|CAC26534.1| percent identity: 41 in 530 aa NP_737206.1 similar to AX065751-1|CAC26115.1| percent identity: 79 in 430 aa NP_737207.1 similar to AX065799-1|CAC26139.1| percent identity: 71 in 224 aa NP_737208.1 similar to AX065801-1|CAC26140.1| percent identity: 82 in 166 aa NP_737209.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_737210.1 similar to AE007158-17|AAK47879.1| percent identity: 38 in 592 aa NP_737211.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP-binding and hydrolysis in the trans ring NP_737212.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth NP_737213.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate NP_737214.1 similar to AF073300-1|AAD19334.1| percent identity: 67 in 90 aa NP_737215.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase NP_737217.1 similar to AL583918-63|CAC29894.1| percent identity: 41 in 113 aa NP_737218.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_737219.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_737221.1 similar to AJ296014-1|CAC27825.1| percent identity: 80 in 461 aa NP_737222.1 similar to AE008212-1|AAK88711.1| percent identity: 62 in 585 aa NP_737225.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_737230.1 similar to AE006366-6|AAK05437.1| percent identity: 39 in 292 aa NP_737232.1 similar to AE006999-1|AAK45475.1| percent identity: 24 in 171 aa NP_737233.1 similar to AX065949-1|CAC26214.1| percent identity: 87 in 230 aa NP_737238.1 similar to AL009198-49|CAA15779.1| percent identity: 41 in 501 aa NP_737239.1 similar to AX066783-1|CAC26619.1| percent identity: 88 in 225 aa NP_737240.1 similar to AX066781-1|CAC26618.1| percent identity: 83 in 359 aa NP_737241.1 similar to AP003359-158|BAB56626.1| percent identity: 32 in 274 aa NP_737242.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. NP_737243.1 similar to AF065442-1|AAD31382.1| percent identity: 29 in 193 aa NP_737244.1 similar to AX066067-1|CAC26273.1| percent identity: 86 in 358 aa NP_737245.1 similar to AL031107-28|CAA19957.1| percent identity: 33 in 291 aa NP_737246.1 similar to AX067019-1|CAC26737.1| percent identity: 59 in 448 aa NP_737247.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin NP_737248.1 similar to Z21955-7|CAA79961.1| percent identity: 25 in 110 aa NP_737249.1 similar to AF159510-5|AAK64300.1| percent identity: 71 in 114 aa NP_737250.1 similar to AF159510-4|AAK64299.1| percent identity: 79 in 524 aa NP_737251.1 similar to AF159510-3|AAK64298.1| percent identity: 69 in 294 aa NP_737252.1 similar to AF159510-2|AAK64297.1| percent identity: 77 in 732 aa NP_737253.1 similar to AF159510-1|AAK64296.1| percent identity: 65 in 374 aa NP_737254.1 similar to AL646057-149|CAD13677.1| percent identity: 26 in 152 aa NP_737255.1 similar to AL627283-99|CAD06819.1| percent identity: 30 in 160 aa NP_737256.1 similar to AP002553-203|BAB34378.1| percent identity: 31 in 474 aa NP_737257.1 similar to AF159509-2|AAK64295.1| percent identity: 64 in 483 aa NP_737258.1 similar to AF159509-1|AAK64294.1| percent identity: 63 in 244 aa NP_737261.1 similar to AE005005-3|AAG19060.1| percent identity: 36 in 215 aa NP_737263.2 Modulates the activities of several enzymes which are inactive in their acetylated form NP_737265.1 similar to AX064831-1|CAC25655.1| percent identity: 49 in 155 aa NP_737266.1 similar to AJ319869-5|CAC42211.1| percent identity: 31 in 405 aa NP_737267.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_737268.1 similar to AE000438-8|AAC76630.1| percent identity: 50 in 152 aa NP_737269.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_737272.1 similar to AX026699-2|CAC09104.1| percent identity: 44 in 435 aa NP_737273.1 similar to X97452-13|CAA66100.1| percent identity: 58 in 431 aa NP_737275.1 similar to AL049485-33|CAB39717.1| percent identity: 24 in 189 aa NP_737276.1 similar to AF176259-6|AAG28967.1| percent identity: 31 in 140 aa NP_737277.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA NP_737278.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation NP_737279.1 similar to AL596248-6|CAC44651.1| percent identity: 42 in 262 aa NP_737280.1 similar to AL596248-7|CAC44652.1| percent identity: 44 in 166 aa NP_737281.1 similar to AL596248-8|CAC44653.1| percent identity: 43 in 380 aa NP_737282.1 similar to AE009003-8|AAL41344.1| percent identity: 33 in 256 aa NP_737283.1 similar to U10895-2|AAA85138.1| percent identity: 55 in 397 aa NP_737284.1 similar to Z92974-1|CAB07495.1| percent identity: 34 in 250 aa NP_737285.1 similar to AE007768-8|AAK80654.1| percent identity: 40 in 272 aa NP_737286.1 similar to AL109732-19|CAB52061.1| percent identity: 52 in 120 aa NP_737287.2 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA NP_737288.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine NP_737289.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol NP_737292.1 similar to X71489-1|CAA50590.1| percent identity: 86 in 729 aa NP_737293.1 similar to Z74024-26|CAA98369.1| percent identity: 33 in 292 aa NP_737294.1 similar to AF176902-3|AAD53128.1| percent identity: 56 in 265 aa NP_737295.1 similar to AE007282-4|AAK65618.1| percent identity: 53 in 339 aa NP_737296.1 similar to AL109848-27|CAB52851.1| percent identity: 42 in 328 aa NP_737297.1 similar to AX067015-1|CAC26735.1| percent identity: 26 in 340 aa NP_737298.1 similar to AL049826-37|CAB42743.1| percent identity: 42 in 378 aa NP_737299.1 similar to U38241-2|AAC44428.1| percent identity: 29 in 301 aa NP_737300.1 similar to AE006133-2|AAK03019.1| percent identity: 57 in 221 aa NP_737302.1 similar to AP001512-172|BAB05304.1| percent identity: 23 in 325 aa NP_737303.1 similar to AX066809-1|CAC26632.1| percent identity: 73 in 258 aa NP_737304.1 similar to AE001826-15|AAF12576.1| percent identity: 40 in 332 aa NP_737306.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_737307.1 similar to AX066191-1|CAC26334.1| percent identity: 73 in 361 aa NP_737309.1 similar to AL391039-16|CAC01548.1| percent identity: 31 in 336 aa NP_737310.1 similar to AE007149-10|AAK47753.1| percent identity: 34 in 403 aa NP_737311.1 similar to AL021957-24|CAA17495.1| percent identity: 35 in 186 aa NP_737314.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_737316.1 similar to AX064907-1|CAC25693.1| percent identity: 78 in 526 aa NP_737317.1 similar to AX065865-1|CAC26172.1| percent identity: 85 in 392 aa NP_737318.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity NP_737319.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate NP_737320.1 catalyzes the hydrolysis of allophanate NP_737321.1 similar to AE004544-8|AAG04536.1| percent identity: 28 in 516 aa NP_737323.1 similar to AE005857-5|AAK23804.1| percent identity: 53 in 1199 aa NP_737324.1 similar to AE008063-7|AAK87160.1| percent identity: 25 in 227 aa NP_737325.1 similar to AE005857-3|AAK23802.1| percent identity: 41 in 267 aa NP_737326.1 similar to AX065475-1|CAC25977.1| percent identity: 74 in 501 aa NP_737327.1 similar to AX065495-1|CAC25987.1| percent identity: 76 in 299 aa NP_737328.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate NP_737329.1 similar to AX066441-1|CAC26448.1| percent identity: 91 in 456 aa NP_737330.1 similar to AL583919-88|CAC30237.1| percent identity: 59 in 297 aa NP_737331.1 similar to AL139074-62|CAB72556.1| percent identity: 61 in 333 aa NP_737332.1 similar to Z99120-167|CAB15273.1| percent identity: 30 in 754 aa NP_737333.1 similar to AB017643-1|BAA82478.1| percent identity: 38 in 407 aa NP_737334.1 similar to AL021246-30|CAA16052.1| percent identity: 29 in 124 aa NP_737335.1 similar to AL646061-27|CAD14498.1| percent identity: 40 in 396 aa NP_737336.1 similar to AE004780-1|AAG06982.1| percent identity: 32 in 291 aa NP_737337.1 similar to AP001517-67|BAB06664.1| percent identity: 32 in 634 aa NP_737339.1 similar to Z84725-12|CAB06591.1| percent identity: 52 in 408 aa NP_737340.1 similar to AX066269-1|CAC26373.1| percent identity: 54 in 363 aa NP_737341.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis NP_737342.1 similar to Z95324-20|CAB08568.1| percent identity: 51 in 129 aa NP_737343.1 similar to AL583921-33|CAC31594.1| percent identity: 36 in 690 aa NP_737345.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_737347.1 similar to AB018531-2|BAA33850.1| percent identity: 91 in 537 aa NP_737348.1 similar to AB018531-1|BAA33849.1| percent identity: 97 in 543 aa NP_737350.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_737352.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_737354.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_737356.1 similar to Z99124-181|CAB16113.1| percent identity: 24 in 178 aa NP_737358.1 similar to AE008348-7|AAK90050.1| percent identity: 44 in 266 aa NP_737359.1 similar to AE007003-8|AAK45532.1| percent identity: 37 in 307 aa NP_737360.1 similar to AP003003-54|BAB50725.1| percent identity: 34 in 147 aa NP_737361.1 similar to AP001511-133|BAB04963.1| percent identity: 29 in 422 aa NP_737362.1 similar to Y08921-1|CAA70125.1| percent identity: 59 in 334 aa NP_737363.1 similar to AL353862-22|CAB88925.1| percent identity: 30 in 214 aa NP_737364.1 similar to U15187-21|AAA63142.1| percent identity: 35 in 508 aa NP_737365.1 similar to AP003596-205|BAB76192.1| percent identity: 24 in 289 aa NP_737366.1 similar to AE007146-8|AAK47705.1| percent identity: 69 in 356 aa NP_737368.1 similar to AF164439-1|AAD47079.1| percent identity: 67 in 100 aa NP_737370.1 similar to AL583919-110|CAC30270.1| percent identity: 48 in 145 aa NP_737371.1 similar to AL353862-11|CAB88914.1| percent identity: 52 in 130 aa NP_737372.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells NP_737373.1 similar to AE007145-16|AAK47696.1| percent identity: 30 in 249 aa NP_737374.1 similar to AE007145-15|AAK47695.1| percent identity: 48 in 396 aa NP_737377.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine NP_737378.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_737379.1 similar to AL355774-15|CAB90924.1| percent identity: 68 in 223 aa NP_737380.1 similar to AE007145-5|AAK47685.1| percent identity: 52 in 483 aa NP_737381.1 similar to AX064851-1|CAC25665.1| percent identity: 66 in 561 aa NP_737382.1 similar to Z95121-17|CAB08343.1| percent identity: 40 in 196 aa NP_737383.1 similar to AL583919-122|CAC30287.1| percent identity: 48 in 221 aa NP_737384.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_737387.1 similar to AE007144-8|AAK47671.1| percent identity: 50 in 167 aa NP_737388.1 similar to AL583919-126|CAC30300.1| percent identity: 64 in 317 aa NP_737389.2 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_737390.1 similar to AL583919-128|CAC30302.1| percent identity: 35 in 216 aa NP_737391.1 similar to AE006945-4|AAK44626.1| percent identity: 33 in 141 aa NP_737392.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response NP_737393.1 similar to AL583919-134|CAC30314.1| percent identity: 80 in 84 aa NP_737394.1 similar to AL583919-135|CAC30316.1| percent identity: 27 in 135 aa NP_737395.1 similar to Z95120-10|CAB08304.1| percent identity: 28 in 397 aa NP_737396.1 similar to AE007143-3|AAK47649.1| percent identity: 58 in 369 aa NP_737397.1 similar to AL390975-32|CAC01370.1| percent identity: 44 in 72 aa NP_737398.1 similar to AL583919-142|CAC30326.1| percent identity: 44 in 278 aa NP_737399.1 similar to AX065623-1|CAC26051.1| percent identity: 74 in 254 aa NP_737400.1 similar to AE007142-5|AAK47639.1| percent identity: 35 in 975 aa NP_737401.1 similar to AL021646-46|CAA16666.1| percent identity: 43 in 1075 aa NP_737402.1 similar to AX067081-1|CAC26768.1| percent identity: 86 in 353 aa NP_737403.1 similar to AK002641-1|BAB22253.1| percent identity: 26 in 223 aa NP_737404.1 similar to AL583919-46|CAC30146.1| percent identity: 55 in 678 aa NP_737406.1 similar to AE007141-7|AAK47629.1| percent identity: 27 in 254 aa NP_737408.1 similar to AL390968-23|CAC01329.1| percent identity: 41 in 477 aa NP_737409.1 similar to AL583919-51|CAC30152.1| percent identity: 43 in 349 aa NP_737411.1 similar to AL390968-27|CAC01333.1| percent identity: 30 in 159 aa NP_737412.1 similar to AE006919-8|AAK44294.1| percent identity: 44 in 988 aa NP_737414.1 Converts oxaloacetate to phosphoenolpyruvate using ATP as an energy source NP_737415.1 similar to AP000983-30|BAB65588.1| percent identity: 53 in 515 aa NP_737416.1 similar to L04196-1|AAA25676.1| percent identity: 34 in 79 aa NP_737417.1 similar to M11738-1|AAA25674.1| percent identity: 52 in 119 aa NP_737418.1 similar to AX065697-1|CAC26088.1| percent identity: 61 in 340 aa NP_737419.1 similar to AX065151-1|CAC25815.1| percent identity: 85 in 260 aa NP_737420.1 similar to AX065163-1|CAC25821.1| percent identity: 77 in 290 aa NP_737421.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_737422.1 similar to AE006518-8|AAK33609.1| percent identity: 54 in 226 aa NP_737423.1 similar to AE007135-6|AAK47523.1| percent identity: 39 in 300 aa NP_737424.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_737425.1 similar to AE000274-4|AAC74862.1| percent identity: 47 in 112 aa NP_737426.1 similar to AE007104-12|AAK47050.1| percent identity: 25 in 398 aa NP_737438.1 similar to AP003360-236|BAB57017.1| percent identity: 32 in 241 aa NP_737439.1 similar to AE006740-1|AAK41495.1| percent identity: 25 in 228 aa NP_737451.1 similar to AE006581-10|AAK34263.1| percent identity: 25 in 487 aa NP_737464.1 similar to AJ312240-12|CAC85568.1| percent identity: 19 in 806 aa NP_737469.1 similar to AL442629-22|CAC10313.1| percent identity: 26 in 459 aa NP_737471.1 similar to AE007096-3|AAK46909.1| percent identity: 27 in 204 aa NP_737476.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis NP_737478.1 similar to AJ414145-24|CAC89701.1| percent identity: 37 in 277 aa NP_737479.1 similar to AJ414158-108|CAC93183.1| percent identity: 32 in 493 aa NP_737480.1 similar to AB047926-3|BAB40635.1| percent identity: 28 in 412 aa NP_737481.1 similar to AE007915-6|AAK90837.1| percent identity: 50 in 385 aa NP_737483.1 similar to AL138667-6|CAB71851.1| percent identity: 48 in 326 aa NP_737484.1 similar to AL078610-26|CAB44399.1| percent identity: 39 in 114 aa NP_737485.1 similar to AX066217-1|CAC26347.1| percent identity: 82 in 370 aa NP_737486.1 similar to AJ251005-2|CAB61257.1| percent identity: 39 in 136 aa NP_737487.1 similar to AE007103-13|AAK47034.1| percent identity: 64 in 134 aa NP_737488.1 similar to AX066219-1|CAC26348.1| percent identity: 70 in 208 aa NP_737489.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_737490.1 similar to AL023635-5|CAA19188.1| percent identity: 39 in 200 aa NP_737491.1 similar to AE008160-4|AAK88208.1| percent identity: 26 in 338 aa NP_737492.1 similar to AE002548-3|AAF42317.1| percent identity: 41 in 311 aa NP_737493.1 similar to AE008160-6|AAK88210.1| percent identity: 38 in 285 aa NP_737494.1 similar to AE002548-6|AAF42320.1| percent identity: 47 in 252 aa NP_737499.1 similar to AX063829-1|CAC25156.1| percent identity: 79 in 387 aa NP_737501.1 similar to AL583924-93|CAC31112.1| percent identity: 75 in 547 aa NP_737502.1 similar to AE006976-11|AAK45126.1| percent identity: 36 in 741 aa NP_737503.1 similar to AL583924-91|CAC31110.1| percent identity: 50 in 62 aa NP_737504.1 similar to AX133781-1|CAC38957.1| percent identity: 71 in 195 aa NP_737505.1 similar to AE006977-4|AAK45135.1| percent identity: 52 in 127 aa NP_737507.1 similar to AE001874-1|AAF09704.1| percent identity: 40 in 267 aa NP_737509.1 similar to AE001862-181|AAF12190.1| percent identity: 36 in 472 aa NP_737510.1 similar to Z73101-8|CAA97388.1| percent identity: 57 in 269 aa NP_737512.1 similar to AE006977-17|AAK45148.1| percent identity: 39 in 238 aa NP_737513.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate NP_737515.2 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH NP_737516.1 similar to X66112-2|CAA46903.1| percent identity: 90 in 118 aa NP_737517.1 similar to AX066443-1|CAC26449.1| percent identity: 62 in 480 aa NP_737518.1 similar to AL646064-175|CAD15202.1| percent identity: 44 in 273 aa NP_737519.1 similar to AL132644-8|CAB59439.1| percent identity: 50 in 109 aa NP_737520.1 similar to AX066927-1|CAC26691.1| percent identity: 90 in 551 aa NP_737522.1 similar to AE007096-3|AAK46909.1| percent identity: 51 in 237 aa NP_737523.1 similar to AE007096-1|AAK46907.1| percent identity: 45 in 2953 aa NP_737524.1 similar to AL109989-23|CAB53437.1| percent identity: 24 in 393 aa NP_737525.1 similar to M31716-1|AAA26773.1| percent identity: 32 in 396 aa NP_737527.1 similar to AL049763-9|CAB42078.1| percent identity: 38 in 78 aa NP_737528.1 similar to AX064397-1|CAC25439.1| percent identity: 65 in 155 aa NP_737529.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_737530.1 similar to AX066423-1|CAC26439.1| percent identity: 86 in 252 aa NP_737531.1 similar to AE007148-9|AAK47738.1| percent identity: 50 in 1489 aa NP_737532.1 similar to D90913-122|BAA18384.1| percent identity: 30 in 257 aa NP_737533.1 similar to AE006977-3|AAK45134.1| percent identity: 58 in 128 aa NP_737534.1 similar to AL356892-18|CAB92836.1| percent identity: 44 in 230 aa NP_737536.1 similar to AL591977-97|CAC99025.1| percent identity: 26 in 391 aa NP_737537.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_737538.1 similar to AP003592-283|BAB75097.1| percent identity: 25 in 347 aa NP_737539.1 similar to AL161755-16|CAB82023.1| percent identity: 31 in 87 aa NP_737540.1 similar to Y15254-6|CAA75552.1| percent identity: 43 in 785 aa NP_737542.1 similar to AL442629-2|CAC10293.1| percent identity: 47 in 218 aa NP_737543.1 similar to AE004331-3|AAF95788.1| percent identity: 22 in 166 aa NP_737544.1 similar to AE006983-1|AAK45225.1| percent identity: 40 in 243 aa NP_737545.1 similar to AX064813-1|CAC25646.1| percent identity: 48 in 469 aa NP_737546.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_737547.1 involved in de novo purine biosynthesis NP_737548.1 similar to AE005011-2|AAG19130.1| percent identity: 33 in 288 aa NP_737549.1 similar to AJ133719-2|CAB52683.1| percent identity: 86 in 223 aa NP_737550.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_737551.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_737552.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_737553.1 required for 70S ribosome assembly NP_737554.1 similar to AF210249-11|AAG02352.1| percent identity: 46 in 537 aa NP_737555.1 similar to AL078610-52|CAB44425.1| percent identity: 47 in 119 aa NP_737556.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_737557.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_737558.1 similar to AE006985-4|AAK45257.1| percent identity: 68 in 233 aa NP_737559.1 similar to AL354616-2|CAB89748.1| percent identity: 35 in 455 aa NP_737560.1 similar to AX065711-1|CAC26095.1| percent identity: 69 in 446 aa NP_737561.1 similar to AX064499-1|CAC25489.1| percent identity: 71 in 196 aa NP_737563.1 similar to AL035500-19|CAB36692.1| percent identity: 42 in 149 aa NP_737564.1 similar to AE006986-2|AAK45266.1| percent identity: 33 in 200 aa NP_737565.1 similar to AE000753-8|AAC07587.1| percent identity: 31 in 184 aa NP_737566.1 similar to AL035500-22|CAB36696.1| percent identity: 63 in 300 aa NP_737567.1 similar to AE006986-6|AAK45270.1| percent identity: 61 in 417 aa NP_737568.1 similar to AL035500-24|CAB36698.1| percent identity: 48 in 205 aa NP_737569.1 similar to AE006986-8|AAK45272.1| percent identity: 26 in 387 aa NP_737570.1 similar to AE008755-18|AAL20203.1| percent identity: 31 in 393 aa NP_737571.1 similar to AE004713-1|AAG06252.1| percent identity: 32 in 126 aa NP_737572.1 similar to AE006921-7|AAK44325.1| percent identity: 26 in 206 aa NP_737573.1 similar to AX065369-1|CAC25924.1| percent identity: 67 in 386 aa NP_737574.1 similar to AE006986-17|AAK45281.1| percent identity: 45 in 477 aa NP_737575.1 similar to AP003004-212|BAB51241.1| percent identity: 38 in 283 aa NP_737576.1 similar to X93514-1|CAA63771.1| percent identity: 76 in 595 aa NP_737577.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_737578.1 similar to AL022374-5|CAA18513.1| percent identity: 55 in 679 aa NP_737579.1 similar to AX066435-1|CAC26445.1| percent identity: 67 in 168 aa NP_737580.1 similar to AX065869-1|CAC26174.1| percent identity: 81 in 275 aa NP_737581.1 similar to AX113822-1|CAC37862.1| percent identity: 65 in 390 aa NP_737582.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_737583.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis NP_737584.1 similar to AE007034-3|AAK45974.1| percent identity: 45 in 614 aa NP_737585.1 similar to AX064267-1|CAC25374.1| percent identity: 54 in 260 aa NP_737587.1 similar to AE006994-9|AAK45406.1| percent identity: 46 in 107 aa NP_737588.1 similar to AE006994-9|AAK45406.1| percent identity: 35 in 106 aa NP_737589.1 similar to AP003588-172|BAB73890.1| percent identity: 58 in 274 aa NP_737590.1 similar to AX065871-1|CAC26175.1| percent identity: 68 in 272 aa NP_737591.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA NP_737594.1 similar to AB055224-1|BAB62413.1| percent identity: 32 in 334 aa NP_737596.1 similar to AB001488-124|BAA19377.1| percent identity: 34 in 794 aa NP_737597.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity NP_737599.1 similar to AE007890-8|AAK90573.1| percent identity: 43 in 215 aa NP_737600.1 similar to AF079317-12|AAD03856.1| percent identity: 46 in 140 aa NP_737601.1 similar to AL162757-214|CAB85173.1| percent identity: 33 in 156 aa NP_737602.1 similar to AE001999-2|AAF11117.1| percent identity: 41 in 540 aa NP_737603.1 similar to AB029154-2|BAA88552.1| percent identity: 80 in 100 aa NP_737604.1 similar to X74600-2|CAA52679.1| percent identity: 50 in 116 aa NP_737605.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_737606.1 involved in the assembly of the urease metallocenter; possible nickel donor NP_737607.1 similar to D14439-5|BAA03327.1| percent identity: 37 in 224 aa NP_737608.1 similar to AP003136-251|BAB43385.1| percent identity: 69 in 200 aa NP_737609.1 similar to AJ251883-7|CAB81941.1| percent identity: 38 in 237 aa NP_737610.1 similar to Y14964-1|CAA75186.1| percent identity: 41 in 406 aa NP_737611.1 similar to AX066881-1|CAC26668.1| percent identity: 88 in 294 aa NP_737613.1 similar to AP001507-249|BAB03968.1| percent identity: 41 in 328 aa NP_737614.1 similar to AE007921-10|AAK90911.1| percent identity: 44 in 243 aa NP_737615.1 similar to AJ414147-12|CAC90032.1| percent identity: 43 in 233 aa NP_737616.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_737617.1 similar to AX065831-1|CAC26155.1| percent identity: 62 in 337 aa NP_737618.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent NP_737621.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_737622.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_737624.1 similar to AL596172-19|CAC97575.1| percent identity: 41 in 201 aa NP_737625.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_737626.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_737628.1 similar to AX065821-1|CAC26150.1| percent identity: 72 in 497 aa NP_737629.1 similar to AL157916-9|CAB76006.1| percent identity: 40 in 307 aa NP_737630.1 similar to AL096839-11|CAB50754.1| percent identity: 25 in 280 aa NP_737631.1 similar to AL118514-9|CAB56353.1| percent identity: 29 in 382 aa NP_737632.1 similar to AE005793-6|AAK23134.1| percent identity: 40 in 207 aa NP_737633.1 similar to AL132856-7|CAB60467.1| percent identity: 33 in 325 aa NP_737635.1 similar to AL646058-59|CAD13780.1| percent identity: 42 in 430 aa NP_737636.1 similar to AP003597-36|BAB76327.1| percent identity: 25 in 286 aa NP_737639.1 similar to AE007085-13|AAK46759.1| percent identity: 55 in 609 aa NP_737643.1 similar to AB070948-1|BAB69295.1| percent identity: 29 in 210 aa NP_737644.1 similar to AE006987-13|AAK45299.1| percent identity: 58 in 1186 aa NP_737645.1 similar to AX063769-1|CAC25126.1| percent identity: 78 in 497 aa NP_737647.1 similar to AL442120-9|CAC09541.1| percent identity: 32 in 202 aa NP_737650.1 similar to AE007003-2|AAK45526.1| percent identity: 35 in 242 aa NP_737651.1 similar to AL591792-181|CAC47585.1| percent identity: 21 in 321 aa NP_737652.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_737654.1 similar to AE006988-4|AAK45303.1| percent identity: 31 in 139 aa NP_737655.1 similar to AE006988-5|AAK45304.1| percent identity: 60 in 161 aa NP_737656.1 similar to AP003593-145|BAB75251.1| percent identity: 29 in 316 aa NP_737657.1 similar to AE004553-1|AAG04624.1| percent identity: 31 in 222 aa NP_737658.1 similar to AE004082-1|AAF85545.1| percent identity: 37 in 226 aa NP_737660.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_737661.1 similar to AE006992-2|AAK45368.1| percent identity: 35 in 150 aa NP_737662.1 similar to AE006992-3|AAK45369.1| percent identity: 59 in 288 aa NP_737664.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive NP_737665.1 similar to AB018379-1|BAA33784.1| percent identity: 45 in 256 aa NP_737667.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_737668.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_737669.1 similar to AJ300302-6|CAC22117.1| percent identity: 50 in 622 aa NP_737672.1 similar to AL136775-1|CAB66709.1| percent identity: 21 in 123 aa NP_737673.1 similar to AE008019-9|AAK86681.1| percent identity: 29 in 174 aa NP_737674.1 similar to AE008292-9|AAK89507.1| percent identity: 37 in 306 aa NP_737675.1 similar to AJ248286-46|CAB49900.1| percent identity: 32 in 217 aa NP_737676.1 similar to AF006000-5|AAC46263.1| percent identity: 45 in 254 aa NP_737677.1 similar to AE008293-1|AAK89510.1| percent identity: 55 in 394 aa NP_737678.1 similar to AE008302-1|AAK89592.1| percent identity: 25 in 219 aa NP_737681.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_737682.1 similar to AL591791-34|CAC47127.1| percent identity: 28 in 206 aa NP_737683.1 similar to AB026669-2|BAB61747.1| percent identity: 34 in 235 aa NP_737685.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese NP_737686.1 similar to AL021897-52|CAA17216.1| percent identity: 24 in 182 aa NP_737687.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_737688.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_737689.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_737691.1 similar to AE006931-3|AAK44436.1| percent identity: 30 in 350 aa NP_737693.1 similar to AE002546-2|AAF42303.1| percent identity: 54 in 511 aa NP_737694.1 similar to AX066045-1|CAC26262.1| percent identity: 64 in 243 aa NP_737695.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_737697.1 similar to AP001518-86|BAB06974.1| percent identity: 40 in 146 aa NP_737698.1 similar to L02354-4|AAA25594.1| percent identity: 32 in 123 aa NP_737699.1 similar to AL132991-40|CAB61310.1| percent identity: 45 in 799 aa NP_737701.1 similar to AL022374-16|CAA18524.1| percent identity: 36 in 112 aa NP_737702.1 similar to AX066927-1|CAC26691.1| percent identity: 68 in 535 aa NP_737703.1 similar to AX067033-1|CAC26744.1| percent identity: 72 in 560 aa NP_737704.1 similar to AE002031-8|AAF11481.1| percent identity: 59 in 127 aa NP_737706.1 similar to AE002014-3|AAF11286.1| percent identity: 29 in 414 aa NP_737707.1 similar to AE005763-4|AAK22847.1| percent identity: 30 in 273 aa NP_737709.1 similar to AP003587-147|BAB73564.1| percent identity: 41 in 357 aa NP_737711.1 similar to AX066385-1|CAC26431.1| percent identity: 72 in 547 aa NP_737712.1 similar to AE007177-16|AAK48178.1| percent identity: 29 in 315 aa NP_737713.1 similar to AB024564-3|BAA83963.1| percent identity: 37 in 289 aa NP_737714.1 similar to AE006983-10|AAK45234.1| percent identity: 58 in 641 aa NP_737715.1 similar to AE006983-9|AAK45233.1| percent identity: 64 in 454 aa NP_737716.1 similar to AX064925-1|CAC25702.1| percent identity: 62 in 223 aa NP_737717.1 similar to AL590507-6|CAC36367.1| percent identity: 36 in 226 aa NP_737718.1 similar to AE007616-5|AAK78983.1| percent identity: 28 in 163 aa NP_737719.1 similar to AP003006-121|BAB51808.1| percent identity: 31 in 229 aa NP_737720.1 similar to AL160312-11|CAB77295.1| percent identity: 37 in 187 aa NP_737721.1 similar to AC004411-27|AAC34218.1| percent identity: 27 in 256 aa NP_737722.1 similar to AX065189-1|CAC25834.1| percent identity: 61 in 289 aa NP_737723.1 similar to AF210249-9|AAG02350.1| percent identity: 57 in 121 aa NP_737724.1 similar to AE000705-9|AAC06912.1| percent identity: 42 in 360 aa NP_737725.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_737726.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_737727.1 similar to D90913-123|BAA18385.1| percent identity: 36 in 223 aa NP_737728.1 similar to AL450350-37|CAC16997.1| percent identity: 42 in 172 aa NP_737729.1 similar to AE001961-5|AAF10690.1| percent identity: 35 in 84 aa NP_737730.1 similar to AP003131-64|BAB41806.1| percent identity: 31 in 234 aa NP_737731.1 similar to AL596144-9|CAC44564.1| percent identity: 34 in 212 aa NP_737732.1 similar to AL355753-4|CAB90886.1| percent identity: 30 in 146 aa NP_737733.1 similar to AF326348-4|AAK15632.1| percent identity: 75 in 353 aa NP_737734.1 catalyzes the formation of acetate from pyruvate NP_737735.1 similar to AE001862-5|AAF12293.1| percent identity: 47 in 390 aa NP_737736.1 similar to AE008766-5|AAL20433.1| percent identity: 29 in 153 aa NP_737739.1 similar to AE004508-6|AAG04121.1| percent identity: 29 in 133 aa NP_737740.1 similar to Z80226-37|CAB02406.1| percent identity: 27 in 246 aa NP_737741.1 similar to AF279141-5|AAK58907.1| percent identity: 37 in 337 aa NP_737743.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate NP_737744.1 similar to AE007934-6|AAK91036.1| percent identity: 22 in 209 aa NP_737745.1 similar to AF397166-9|AAL04084.1| percent identity: 28 in 447 aa NP_737746.1 similar to AX066851-1|CAC26653.1| percent identity: 72 in 251 aa NP_737748.1 similar to AX067013-1|CAC26734.1| percent identity: 59 in 353 aa NP_737749.1 similar to AL136502-15|CAB66204.1| percent identity: 44 in 249 aa NP_737750.1 similar to AE007658-2|AAK79432.1| percent identity: 46 in 776 aa NP_737751.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_737754.1 similar to AE004611-11|AAG05246.1| percent identity: 38 in 315 aa NP_737755.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_737757.1 similar to AE001887-6|AAF09846.1| percent identity: 33 in 139 aa NP_737759.1 similar to AX065731-1|CAC26105.1| percent identity: 45 in 252 aa NP_737760.1 similar to AX066287-1|CAC26382.1| percent identity: 72 in 115 aa NP_737762.1 similar to AX067009-1|CAC26732.1| percent identity: 78 in 399 aa NP_737763.1 similar to AE007030-11|AAK45938.1| percent identity: 42 in 146 aa NP_737764.1 similar to AF310674-1|AAG39999.1| percent identity: 24 in 216 aa NP_737766.1 similar to AL596043-7|CAC44318.1| percent identity: 60 in 632 aa NP_737767.1 similar to AX067055-1|CAC26755.1| percent identity: 55 in 527 aa NP_737768.1 similar to AE006998-5|AAK45464.1| percent identity: 42 in 283 aa NP_737770.1 similar to AE006998-12|AAK45471.1| percent identity: 71 in 105 aa NP_737771.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis NP_737773.1 similar to AE007001-2|AAK45496.1| percent identity: 64 in 307 aa NP_737774.1 similar to AL138662-1|CAB71806.1| percent identity: 45 in 456 aa NP_737775.1 similar to AL583920-143|CAC31439.1| percent identity: 45 in 311 aa NP_737776.2 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate NP_737777.1 similar to AX066691-1|CAC26573.1| percent identity: 85 in 260 aa NP_737778.1 similar to AP001507-93|BAB03812.1| percent identity: 36 in 276 aa NP_737779.1 similar to AE007001-9|AAK45503.1| percent identity: 48 in 228 aa NP_737780.1 similar to AL390975-5|CAC01343.1| percent identity: 31 in 92 aa NP_737781.1 similar to AB012767-2|BAA33549.1| percent identity: 37 in 53 aa NP_737782.1 similar to AF121000-10|AAD25062.1| percent identity: 36 in 284 aa NP_737784.1 similar to D90905-118|BAA17400.1| percent identity: 27 in 390 aa NP_737785.2 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_737786.1 similar to AX196012-1|CAC60032.1| percent identity: 26 in 208 aa NP_737787.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein is involved in heat shock, oxidative stress and virulence NP_737790.1 similar to AJ292256-1|CAC21724.1| percent identity: 26 in 155 aa NP_737791.1 similar to AL390975-15|CAC01353.1| percent identity: 63 in 370 aa NP_737793.1 similar to AE007003-3|AAK45527.1| percent identity: 57 in 159 aa NP_737794.1 similar to AE007003-4|AAK45528.1| percent identity: 52 in 417 aa NP_737795.1 similar to AE007003-6|AAK45530.1| percent identity: 60 in 155 aa NP_737797.1 similar to AE007262-3|AAK65408.1| percent identity: 32 in 235 aa NP_737799.1 similar to AF024666-23|AAG03374.1| percent identity: 84 in 408 aa NP_737800.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth NP_737801.1 similar to AE008826-11|AAL21660.1| percent identity: 36 in 1238 aa NP_737802.1 similar to M57505-2|AAA47468.1| percent identity: 25 in 576 aa NP_737803.1 similar to AE007004-6|AAK45545.1| percent identity: 33 in 228 aa NP_737804.1 catalyzes the conversion of shikimate to 3-dehydroshikimate NP_737807.1 similar to AL021899-31|CAA17259.1| percent identity: 35 in 505 aa NP_737810.1 similar to AF034831-1|AAC64871.1| percent identity: 44 in 67 aa NP_737811.1 similar to AL133278-1|CAB61912.1| percent identity: 31 in 334 aa NP_737812.1 similar to AB010645-3|BAA31463.1| percent identity: 39 in 255 aa NP_737813.1 similar to AE008352-1|AAK90083.1| percent identity: 30 in 255 aa NP_737814.1 similar to AE001796-3|AAD36511.1| percent identity: 28 in 106 aa NP_737817.1 similar to AX066357-1|CAC26417.1| percent identity: 81 in 393 aa NP_737818.1 similar to AX066355-1|CAC26416.1| percent identity: 77 in 447 aa NP_737819.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_737820.1 similar to AE002551-1|AAF42336.1| percent identity: 33 in 327 aa NP_737823.1 similar to AP003011-197|BAB53457.1| percent identity: 58 in 443 aa NP_737825.1 similar to AJ245436-5|CAB54047.1| percent identity: 39 in 186 aa NP_737826.1 similar to AY065402-1|AAL38843.1| percent identity: 25 in 223 aa NP_737827.1 similar to Y18016-1|CAB82508.1| percent identity: 26 in 388 aa NP_737830.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_737831.1 similar to AL591793-30|CAC47725.1| percent identity: 38 in 440 aa NP_737832.1 similar to AE000099-8|AAB91881.1| percent identity: 29 in 434 aa NP_737833.1 similar to L09108-2|AAA25862.1| percent identity: 45 in 187 aa NP_737834.1 similar to AE007150-15|AAK47773.1| percent identity: 32 in 387 aa NP_737835.1 similar to X69104-2|CAA48850.1| percent identity: 89 in 298 aa NP_737836.1 similar to X69104-1|CAA48849.1| percent identity: 78 in 102 aa NP_737837.1 similar to AF232829-4|AAL02534.1| percent identity: 42 in 107 aa NP_737838.1 similar to U50076-1|AAB40345.1| percent identity: 49 in 100 aa NP_737839.1 similar to SwissProt:P55923 percent identity: 34 in 211 aa NP_737840.1 similar to PIR:S60890 percent identity: 89 in 298 aa NP_737841.1 similar to PIR:S60889 percent identity: 90 in 97 aa NP_737843.1 similar to PIR:H95314 percent identity: 38 in 170 aa NP_737844.1 similar to PIR:S60889 percent identity: 82 in 297 aa NP_737845.1 similar to PIR:S60890 percent identity: 90 in 298 aa NP_737846.1 similar to PIR:T34886 percent identity: 40 in 330 aa NP_737847.1 similar to SwissProt:P55379 percent identity: 31 in 226 aa NP_737848.1 similar to X79443-2|CAA55960.1| percent identity: 31 in 182 aa NP_737849.1 similar to AY033500-1|AAK51146.1| percent identity: 57 in 97 aa NP_737850.1 similar to X69104-2|CAA48850.1| percent identity: 88 in 298 aa NP_737851.1 similar to AC006577-17|AAD25781.1| percent identity: 50 in 32 aa NP_737852.1 similar to Z95390-28|CAB08699.1| percent identity: 40 in 167 aa NP_737853.1 similar to AF163691-2|AAF22730.1| percent identity: 46 in 139 aa NP_737854.1 similar to D64144-1|BAA33969.1| percent identity: 28 in 462 aa NP_737855.1 similar to X14793-3|CAA32899.2| percent identity: 39 in 216 aa NP_737858.1 similar to AL646083-21|CAD18286.1| percent identity: 34 in 91 aa NP_737860.1 similar to AE009340-9|AAL44891.1| percent identity: 31 in 511 aa NP_737861.1 similar to AL034355-14|CAA22219.1| percent identity: 35 in 508 aa NP_737862.1 similar to AE007030-1|AAK45928.1| percent identity: 50 in 337 aa NP_737863.1 similar to AX065515-1|CAC25997.1| percent identity: 80 in 500 aa NP_737864.1 similar to AE006100-5|AAK02722.1| percent identity: 26 in 284 aa NP_737865.1 similar to AJ307662-45|CAC39074.1| percent identity: 29 in 77 aa NP_737866.1 similar to AE007104-15|AAK47053.1| percent identity: 34 in 78 aa NP_737867.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate NP_737868.1 similar to AX067029-1|CAC26742.1| percent identity: 89 in 463 aa NP_737869.1 similar to L08387-1|AAA61345.1| percent identity: 49 in 636 aa NP_737871.1 similar to AL590463-31|CAC36553.1| percent identity: 29 in 128 aa NP_737872.1 similar to Y09163-1|CAA70363.1| percent identity: 83 in 523 aa NP_737873.1 similar to AL021924-1|CAA17284.1| percent identity: 42 in 804 aa NP_737875.1 similar to AP003193-65|BAB81866.1| percent identity: 21 in 381 aa NP_737876.1 similar to AE007006-8|AAK45576.1| percent identity: 31 in 872 aa NP_737878.1 similar to AE005695-1|AAK22193.1| percent identity: 53 in 231 aa NP_737879.1 similar to AJ293315-3|CAC33602.1| percent identity: 58 in 211 aa NP_737880.1 similar to AE005014-5|AAG19170.1| percent identity: 39 in 356 aa NP_737882.1 similar to AL583945-34|CAC32370.1| percent identity: 32 in 194 aa NP_737883.1 similar to AL355832-22|CAB90989.1| percent identity: 36 in 139 aa NP_737885.1 similar to AL137166-19|CAB69737.1| percent identity: 28 in 515 aa NP_737886.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_737887.1 similar to AF126720-2|AAD32591.1| percent identity: 57 in 451 aa NP_737890.1 similar to AL132707-20|CAB59718.1| percent identity: 29 in 211 aa NP_737892.1 similar to AE007222-3|AAK64953.1| percent identity: 37 in 311 aa NP_737899.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine NP_737900.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_737901.1 similar to M31716-1|AAA26773.1| percent identity: 32 in 396 aa NP_737903.1 similar to AX065947-1|CAC26213.1| percent identity: 85 in 259 aa NP_737904.1 similar to AL109989-28|CAB53442.1| percent identity: 40 in 231 aa NP_737905.1 similar to AE006997-10|AAK45456.1| percent identity: 61 in 532 aa NP_737906.1 similar to AL031515-20|CAA20632.1| percent identity: 56 in 1246 aa NP_737907.1 similar to AX065967-1|CAC26223.1| percent identity: 82 in 445 aa NP_737908.1 similar to AX064505-1|CAC25492.1| percent identity: 62 in 162 aa NP_737910.1 similar to AL591788-18|CAC46242.1| percent identity: 33 in 407 aa NP_737911.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_737912.1 activates fatty acids by binding to coenzyme A NP_737913.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_737914.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_737915.1 similar to AL359152-5|CAB94532.1| percent identity: 46 in 280 aa NP_737916.1 similar to AX244025-1|CAC88491.1| percent identity: 88 in 216 aa NP_737917.1 similar to AL583920-196|CAC31518.1| percent identity: 54 in 371 aa NP_737919.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_737920.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_737921.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_737922.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_737923.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit NP_737924.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_737925.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit NP_737926.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_737927.1 similar to AL359152-19|CAB94546.1| percent identity: 32 in 134 aa NP_737928.1 similar to AE007009-10|AAK45625.1| percent identity: 74 in 230 aa NP_737929.1 similar to AL359152-35|CAB94562.1| percent identity: 48 in 92 aa NP_737930.1 similar to AL583921-2|CAC31538.1| percent identity: 53 in 137 aa NP_737931.1 similar to AE000771-2|AAC07822.1| percent identity: 35 in 100 aa NP_737932.1 similar to Z73902-9|CAA98088.1| percent identity: 38 in 301 aa NP_737933.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_737934.1 similar to AE007010-6|AAK45633.1| percent identity: 60 in 669 aa NP_737935.1 similar to AE007130-17|AAK47456.1| percent identity: 62 in 269 aa NP_737936.1 similar to AE005902-5|AAK24293.1| percent identity: 28 in 252 aa NP_737937.1 similar to AL031317-36|CAA20414.1| percent identity: 30 in 378 aa NP_737938.1 similar to AX065555-1|CAC26017.1| percent identity: 78 in 260 aa NP_737939.1 similar to AE007130-3|AAK47442.1| percent identity: 55 in 317 aa NP_737940.1 similar to AL583923-39|CAC30661.1| percent identity: 48 in 369 aa NP_737942.1 similar to AX064063-1|CAC25272.1| percent identity: 79 in 289 aa NP_737944.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_737945.1 similar to AX244093-1|CAC88525.1| percent identity: 67 in 335 aa NP_737947.1 similar to AB070943-1|BAB69223.1| percent identity: 30 in 481 aa NP_737949.1 3'-5' exonuclease of DNA polymerase III NP_737948.2 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_737950.1 similar to M37002-1|AAA25202.1| percent identity: 26 in 140 aa NP_737951.1 similar to M37002-1|AAA25202.1| percent identity: 39 in 145 aa NP_737952.1 similar to AL021287-27|CAA16098.1| percent identity: 42 in 218 aa NP_737954.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_737955.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_737956.1 similar to AL132648-6|CAB59476.1| percent identity: 45 in 271 aa NP_737957.1 similar to AL021309-6|CAA16144.1| percent identity: 27 in 107 aa NP_737958.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_737959.1 similar to AX065267-1|CAC25873.1| percent identity: 46 in 333 aa NP_737960.1 similar to AL136519-25|CAB66294.1| percent identity: 39 in 194 aa NP_737961.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_737962.1 similar to AP003001-232|BAB50231.1| percent identity: 59 in 354 aa NP_737963.1 similar to AL359152-39|CAB94566.1| percent identity: 54 in 301 aa NP_737964.1 similar to AL031155-29|CAA20092.1| percent identity: 31 in 259 aa NP_737965.1 similar to AL359779-17|CAB95290.1| percent identity: 33 in 381 aa NP_737966.1 similar to AL049754-31|CAB42040.1| percent identity: 52 in 219 aa NP_737967.1 similar to X96471-2|CAA65324.2| percent identity: 71 in 228 aa NP_737968.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport NP_737969.1 similar to AX065613-1|CAC26046.1| percent identity: 90 in 358 aa NP_737970.1 similar to AL590464-141|CAC36848.1| percent identity: 29 in 218 aa NP_737971.1 similar to AL583923-29|CAC30651.1| percent identity: 29 in 288 aa NP_737972.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_737974.1 similar to AL138662-26|CAB71831.1| percent identity: 29 in 278 aa NP_737975.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate NP_737976.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_737977.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_737978.1 similar to X61625-4|CAA43812.1| percent identity: 44 in 236 aa NP_737979.1 similar to Z19598-3|CAA79657.1| percent identity: 39 in 258 aa NP_737980.1 similar to L27431-1|AAB86900.1| percent identity: 29 in 324 aa NP_737981.1 similar to AP003129-173|BAB41390.1| percent identity: 23 in 325 aa NP_737982.1 similar to AL590464-46|CAC36752.1| percent identity: 32 in 152 aa NP_737984.1 similar to AX066993-1|CAC26724.1| percent identity: 80 in 251 aa NP_737985.1 similar to AL031371-12|CAA20549.1| percent identity: 33 in 577 aa NP_737988.1 similar to M86664-71|AAB02506.1| percent identity: 25 in 140 aa NP_737989.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_737991.1 similar to X81318-1|CAA57098.1| percent identity: 22 in 157 aa NP_737993.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_737994.1 similar to AE004208-6|AAF94450.1| percent identity: 33 in 614 aa NP_737995.1 similar to AE004208-5|AAF94449.1| percent identity: 37 in 213 aa NP_737996.1 similar to AL031124-27|CAA19994.1| percent identity: 43 in 265 aa NP_737997.1 similar to AL096837-25|CAB48912.1| percent identity: 42 in 143 aa NP_737998.1 synthesizes isochorismate acid from chorismate NP_737999.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_738000.1 similar to AE007754-1|AAK80503.1| percent identity: 62 in 67 aa NP_738001.1 similar to AL592126-6|CAC42141.1| percent identity: 31 in 157 aa NP_738004.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport NP_738006.1 similar to Z93932-9|CAB07908.1| percent identity: 27 in 519 aa NP_738007.1 similar to AJ245399-4|CAC14148.1| percent identity: 39 in 487 aa NP_738008.1 similar to AL646068-9|CAD15757.1| percent identity: 25 in 430 aa NP_738012.1 similar to AL646060-24|CAD14109.1| percent identity: 40 in 47 aa NP_738014.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_738015.1 similar to X69104-2|CAA48850.1| percent identity: 56 in 266 aa NP_738016.1 similar to AE005986-9|AAK25185.1| percent identity: 25 in 143 aa NP_738017.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_738019.1 similar to AL021841-25|CAA17099.1| percent identity: 31 in 377 aa NP_738020.1 similar to U62766-1|AAB05796.1| percent identity: 62 in 98 aa NP_738021.1 similar to U95315-1|AAB54011.1| percent identity: 61 in 241 aa NP_738022.1 similar to AJ414142-106|CAC89255.1| percent identity: 22 in 367 aa NP_738023.1 similar to AE004080-1|AAF85519.1| percent identity: 27 in 1087 aa NP_738025.1 similar to AE004079-9|AAF85518.1| percent identity: 27 in 460 aa NP_738026.1 similar to AF295359-4|AAK61313.1| percent identity: 38 in 406 aa NP_738027.1 similar to Z99110-199|CAB13174.1| percent identity: 45 in 151 aa NP_738028.1 similar to AP003358-116|BAB56278.1| percent identity: 39 in 305 aa NP_738029.1 similar to AX244053-1|CAC88505.1| percent identity: 76 in 660 aa NP_738030.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_738031.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_738033.1 similar to AL596165-116|CAC95796.1| percent identity: 32 in 474 aa NP_738034.1 similar to AP003597-79|BAB76370.1| percent identity: 35 in 183 aa NP_738036.1 similar to AL031124-33|CAA20000.1| percent identity: 44 in 223 aa NP_738037.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_738038.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_738039.1 similar to AX064755-1|CAC25617.1| percent identity: 82 in 337 aa NP_738040.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_738041.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_738042.1 similar to Z99121-84|CAB15403.1| percent identity: 42 in 323 aa NP_738045.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_738046.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_738047.1 similar to AL034447-9|CAA22408.1| percent identity: 33 in 549 aa NP_738048.1 similar to Z83018-24|CAB05438.1| percent identity: 42 in 698 aa NP_738049.1 similar to AX065047-1|CAC25763.1| percent identity: 82 in 41 aa NP_738050.1 similar to AE006445-4|AAK06261.1| percent identity: 34 in 183 aa NP_738051.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_738052.1 similar to AP000061-47|BAA80182.1| percent identity: 24 in 244 aa NP_738053.1 similar to AE007304-3|AAK65843.1| percent identity: 58 in 253 aa NP_738054.1 similar to AE007304-4|AAK65844.1| percent identity: 47 in 211 aa NP_738056.1 similar to AL391763-22|CAC05959.1| percent identity: 30 in 303 aa NP_738059.1 similar to AF132735-7|AAF61311.1| percent identity: 24 in 275 aa NP_738061.1 similar to AE001701-10|AAD35257.1| percent identity: 26 in 286 aa NP_738063.1 similar to AE006007-10|AAK25451.1| percent identity: 31 in 320 aa NP_738065.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_738066.1 similar to AX064605-1|CAC25542.1| percent identity: 77 in 242 aa NP_738067.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_738068.1 similar to L18875-1|AAA22992.1| percent identity: 83 in 687 aa NP_738069.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_738073.1 similar to AE000066-7|AAB91628.1| percent identity: 27 in 249 aa NP_738075.1 similar to AL646058-59|CAD13780.1| percent identity: 42 in 430 aa NP_738076.1 similar to U50076-1|AAB40345.1| percent identity: 49 in 100 aa NP_738077.1 similar to Z83860-22|CAB06167.1| percent identity: 43 in 281 aa NP_738078.1 similar to AF292393-1|AAK12893.1| percent identity: 32 in 354 aa NP_738083.1 similar to AL603645-216|CAC49421.1| percent identity: 27 in 341 aa NP_738086.1 similar to AK001216-1|BAA91560.1| percent identity: 27 in 172 aa NP_738090.1 similar to AJ248283-35|CAB48959.1| percent identity: 38 in 139 aa NP_738092.1 similar to AX064775-1|CAC25627.1| percent identity: 90 in 312 aa NP_738093.1 similar to AE006394-2|AAK05732.1| percent identity: 57 in 465 aa NP_738094.1 similar to AX065265-1|CAC25872.1| percent identity: 60 in 297 aa NP_738095.1 similar to AX065267-1|CAC25873.1| percent identity: 64 in 332 aa NP_738096.1 similar to AE008906-10|AAL23218.1| percent identity: 63 in 429 aa NP_738098.1 similar to AB055224-1|BAB62413.1| percent identity: 31 in 287 aa NP_738100.1 similar to AJ420072-16|CAD12220.1| percent identity: 72 in 139 aa NP_738101.1 similar to AJ315451-6|CAC48059.1| percent identity: 31 in 80 aa NP_738102.1 similar to AJ420072-16|CAD12220.1| percent identity: 76 in 235 aa NP_738103.1 similar to AP002564-225|BAB37557.1| percent identity: 27 in 317 aa NP_738106.1 similar to X63715-1|CAA45248.1| percent identity: 44 in 386 aa NP_738108.1 similar to AE006972-1|AAK45060.1| percent identity: 31 in 342 aa NP_738109.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_738110.1 similar to AL596169-67|CAC96846.1| percent identity: 31 in 143 aa NP_738111.1 similar to AX066219-1|CAC26348.1| percent identity: 31 in 152 aa NP_738112.1 similar to AL138978-15|CAB72415.1| percent identity: 43 in 748 aa NP_738114.1 similar to AX066555-1|CAC26505.1| percent identity: 83 in 200 aa NP_738115.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_738119.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_738120.1 similar to AL031541-21|CAA20810.1| percent identity: 58 in 62 aa NP_738121.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_738123.1 similar to AL049573-31|CAB40339.1| percent identity: 55 in 129 aa NP_738124.1 similar to AX067079-1|CAC26767.1| percent identity: 86 in 305 aa NP_738125.1 similar to AP003597-232|BAB76523.1| percent identity: 34 in 275 aa NP_738126.1 similar to Z81331-38|CAB03653.1| percent identity: 49 in 431 aa NP_738127.1 similar to Y08921-1|CAA70125.1| percent identity: 52 in 395 aa NP_738129.1 similar to AE009005-6|AAL41363.1| percent identity: 32 in 272 aa NP_738130.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_738131.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_738132.1 similar to AL096849-14|CAB50940.1| percent identity: 23 in 272 aa NP_738133.1 similar to D31821-2|BAA06607.1| percent identity: 27 in 411 aa NP_738135.1 similar to AE000692-9|AAC06741.1| percent identity: 30 in 224 aa NP_738136.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_738137.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate NP_738138.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_738139.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine NP_738140.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation NP_738141.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_738142.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming NP_738143.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_738144.1 similar to AL627283-159|CAD06881.1| percent identity: 40 in 115 aa NP_738145.1 similar to AE004431-3|AAF96948.1| percent identity: 30 in 165 aa NP_738147.1 similar to AP003596-115|BAB76102.1| percent identity: 24 in 397 aa NP_738149.1 similar to BC007876-1|AAH07876.1| percent identity: 53 in 56 aa NP_738150.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_738153.1 similar to AP000001-226|BAA29291.1| percent identity: 44 in 159 aa NP_738154.1 similar to AE007035-10|AAK45999.1| percent identity: 50 in 216 aa NP_738155.1 similar to Z98268-13|CAB10949.1| percent identity: 40 in 329 aa NP_738156.1 similar to AL583921-123|CAC31739.1| percent identity: 54 in 273 aa NP_738157.1 catalyzes the phosphorylation of NAD to NADP NP_738158.1 similar to Z95117-12|CAB08275.1| percent identity: 50 in 576 aa NP_738159.1 similar to U00021-17|AAA50907.1| percent identity: 43 in 388 aa NP_738160.1 similar to AL646083-66|CAD18331.1| percent identity: 21 in 319 aa NP_738161.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_738162.1 similar to AX064847-1|CAC25663.1| percent identity: 73 in 222 aa NP_738163.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_738164.1 similar to Z98268-29|CAB10965.1| percent identity: 68 in 274 aa NP_738165.1 similar to Z95117-5|CAB08281.1| percent identity: 58 in 253 aa NP_738166.1 similar to Z99114-17|CAB13746.1| percent identity: 26 in 148 aa NP_738167.1 similar to AF109156-1|AAD19957.1| percent identity: 37 in 275 aa NP_738168.1 similar to AL583921-132|CAC31750.1| percent identity: 57 in 180 aa NP_738169.1 similar to AL109848-8|CAB52832.1| percent identity: 43 in 329 aa NP_738170.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_738171.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_738173.1 similar to AE004492-6|AAG03947.1| percent identity: 28 in 233 aa NP_738174.1 similar to X89010-3|CAA61416.1| percent identity: 26 in 495 aa NP_738175.1 similar to AL109974-12|CAB53323.1| percent identity: 39 in 582 aa NP_738176.1 similar to AP003187-239|BAB80427.1| percent identity: 53 in 265 aa NP_738177.1 similar to AF132735-7|AAF61311.1| percent identity: 24 in 275 aa NP_738178.1 similar to AF262989-2|AAF71375.1| percent identity: 33 in 549 aa NP_738179.1 similar to AL450165-2|CAC16428.1| percent identity: 64 in 292 aa NP_738180.1 similar to AB070954-6|BAB69372.1| percent identity: 46 in 122 aa NP_738181.1 similar to AE007290-8|AAK65702.1| percent identity: 36 in 386 aa NP_738182.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins NP_738183.1 similar to AE007046-6|AAK46148.1| percent identity: 73 in 132 aa NP_738184.1 similar to AL353861-3|CAB88879.1| percent identity: 39 in 233 aa NP_738185.1 similar to AE007046-8|AAK46150.1| percent identity: 27 in 160 aa NP_738186.1 similar to Z78020-17|CAB01472.1| percent identity: 70 in 186 aa NP_738187.1 similar to AE001763-4|AAD36092.1| percent identity: 34 in 364 aa NP_738188.1 similar to AJ414148-36|CAC90226.1| percent identity: 34 in 442 aa NP_738189.1 similar to AL020958-15|CAA15882.1| percent identity: 40 in 227 aa NP_738190.1 similar to AE005854-5|AAK23772.1| percent identity: 27 in 375 aa NP_738193.1 similar to AJ301559-3|CAC35700.1| percent identity: 44 in 282 aa NP_738194.1 similar to AX065387-1|CAC25933.1| percent identity: 81 in 352 aa NP_738195.1 similar to Z83859-5|CAB06112.1| percent identity: 48 in 443 aa NP_738196.1 similar to AL646059-158|CAD14067.1| percent identity: 37 in 457 aa NP_738197.1 similar to AX064887-1|CAC25683.1| percent identity: 81 in 486 aa NP_738198.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_738199.1 similar to AX064611-1|CAC25545.1| percent identity: 67 in 143 aa NP_738200.1 similar to AX064603-1|CAC25541.1| percent identity: 77 in 193 aa NP_738201.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate NP_738202.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP NP_738203.1 similar to AJ238250-1|CAB41413.1| percent identity: 85 in 464 aa NP_738204.1 similar to AX066487-1|CAC26471.1| percent identity: 73 in 438 aa NP_738205.1 similar to AX066919-1|CAC26687.1| percent identity: 83 in 465 aa NP_738206.1 similar to AL078610-7|CAB44380.1| percent identity: 57 in 157 aa NP_738208.1 similar to AE005405-1|AAG56810.1| percent identity: 37 in 196 aa NP_738209.1 similar to AE000865-11|AAB85398.1| percent identity: 23 in 317 aa NP_738212.1 similar to AL096743-33|CAB46416.1| percent identity: 59 in 217 aa NP_738214.1 similar to AE007062-1|AAK46388.1| percent identity: 45 in 100 aa NP_738215.1 similar to Z98604-3|CAB11301.1| percent identity: 71 in 100 aa NP_738216.1 similar to AX067093-1|CAC26774.1| percent identity: 83 in 271 aa NP_738217.1 similar to AE007062-3|AAK46390.1| percent identity: 39 in 547 aa NP_738218.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein NP_738219.1 similar to AX065909-1|CAC26194.1| percent identity: 60 in 438 aa NP_738220.1 similar to AL591792-99|CAC47503.1| percent identity: 26 in 263 aa NP_738221.1 similar to AX064531-1|CAC25505.1| percent identity: 49 in 459 aa NP_738222.1 probable dehydrogenase NP_738223.1 similar to AX065767-1|CAC26123.1| percent identity: 76 in 381 aa NP_738225.1 similar to AE000488-5|AAC77119.1| percent identity: 41 in 48 aa NP_738227.1 similar to AP003596-73|BAB76060.1| percent identity: 31 in 64 aa NP_738228.1 similar to AL132648-14|CAB59484.1| percent identity: 46 in 936 aa NP_738229.1 similar to AX064127-1|CAC25304.1| percent identity: 72 in 313 aa NP_738230.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes NP_738231.1 similar to AL132648-19|CAB59489.1| percent identity: 29 in 324 aa NP_738232.1 similar to Z82004-3|CAB04763.1| percent identity: 29 in 314 aa NP_738233.1 similar to AL583921-107|CAC31709.1| percent identity: 55 in 464 aa NP_738234.1 similar to AE007066-4|AAK46454.1| percent identity: 52 in 63 aa NP_738235.1 similar to AL035310-14|CAA22931.1| percent identity: 47 in 506 aa NP_738236.1 similar to AF088800-4|AAC68690.1| percent identity: 50 in 507 aa NP_738237.1 similar to AX065925-1|CAC26202.1| percent identity: 89 in 278 aa NP_738238.1 catalyzes the removal of amino acids from the N termini of peptides NP_738239.1 similar to AF088800-1|AAC68687.1| percent identity: 50 in 279 aa NP_738240.1 similar to AE005227-6|AAG54832.1| percent identity: 35 in 79 aa NP_738241.1 similar to Z99122-142|CAB15662.1| percent identity: 31 in 370 aa NP_738242.1 similar to AB005554-8|BAA21583.1| percent identity: 36 in 135 aa NP_738243.1 catalyzes the formation of fumarate from aspartate NP_738244.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors NP_738245.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis NP_738246.1 similar to AX065511-1|CAC25995.1| percent identity: 70 in 229 aa NP_738247.1 similar to AL499607-2|CAC18788.1| percent identity: 63 in 1211 aa NP_738248.1 similar to M80346-1|AAC32027.1| percent identity: 28 in 127 aa NP_738249.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_738250.2 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell NP_738251.1 similar to AF242881-61|AAB07785.1| percent identity: 33 in 316 aa NP_738252.1 similar to AF024666-10|AAG03364.1| percent identity: 41 in 326 aa NP_738253.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors NP_738255.1 similar to AF024666-8|AAG03362.1| percent identity: 65 in 176 aa NP_738256.1 similar to AL109974-12|CAB53323.1| percent identity: 33 in 599 aa NP_738257.1 similar to U21300-3|AAC95479.1| percent identity: 40 in 520 aa NP_738258.1 similar to AF104994-9|AAF25539.1| percent identity: 28 in 200 aa NP_738259.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins NP_738260.1 MDM; functions in conversion of succinate to propionate NP_738261.1 similar to AX065505-1|CAC25992.1| percent identity: 68 in 618 aa NP_738262.1 similar to Z79701-10|CAB02041.1| percent identity: 42 in 199 aa NP_738264.1 similar to AX063901-1|CAC25192.1| percent identity: 80 in 418 aa NP_738265.1 similar to AP003589-191|BAB74170.1| percent identity: 27 in 141 aa NP_738266.1 similar to AE007060-3|AAK46372.1| percent identity: 47 in 266 aa NP_738267.1 similar to AL583923-87|CAC30757.1| percent identity: 25 in 246 aa NP_738268.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_738269.1 similar to AL021184-24|CAA16005.1| percent identity: 34 in 456 aa NP_738271.1 Catalyzes the conversion of citrate to isocitrate NP_738273.1 similar to AE007021-9|AAK45786.1| percent identity: 56 in 174 aa NP_738274.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group NP_738275.1 similar to AF132735-7|AAF61311.1| percent identity: 21 in 275 aa NP_738276.1 similar to Y14083-20|CAA74532.1| percent identity: 30 in 217 aa NP_738278.2 ACT domain-containing protein NP_738279.1 similar to AE007562-6|AAK78459.1| percent identity: 61 in 449 aa NP_738280.1 similar to AJ414142-155|CAC89307.1| percent identity: 45 in 892 aa NP_738281.1 similar to AE007102-2|AAK47007.1| percent identity: 32 in 160 aa NP_738282.1 similar to AL132973-38|CAB61195.1| percent identity: 44 in 56 aa NP_738283.1 similar to AL596030-4|CAC44276.1| percent identity: 47 in 109 aa NP_738284.1 similar to AP003000-69|BAB49724.1| percent identity: 29 in 64 aa NP_738285.1 similar to AF104994-9|AAF25539.1| percent identity: 29 in 183 aa NP_738286.1 similar to AP003013-287|BAB53880.1| percent identity: 32 in 96 aa NP_738288.1 similar to AL583923-98|CAC30769.1| percent identity: 67 in 543 aa NP_738290.1 similar to X74599-1|CAA52677.1| percent identity: 23 in 410 aa NP_738291.1 similar to AE007020-14|AAK45777.1| percent identity: 66 in 115 aa NP_738292.1 similar to AL021184-12|CAA15995.1| percent identity: 64 in 146 aa NP_738293.1 similar to AX064375-1|CAC25428.1| percent identity: 86 in 421 aa NP_738294.1 similar to AX066775-1|CAC26615.1| percent identity: 93 in 252 aa NP_738295.1 similar to Z99125-22|CAB16170.1| percent identity: 54 in 391 aa NP_738296.1 similar to AX224772-1|CAC69582.1| percent identity: 81 in 480 aa NP_738297.1 similar to AL096839-8|CAB50751.1| percent identity: 45 in 232 aa NP_738298.1 similar to U00013-11|AAA17136.1| percent identity: 38 in 510 aa NP_738299.1 similar to AL583919-19|CAC30098.1| percent identity: 51 in 319 aa NP_738300.1 similar to U00013-14|AAA17143.1| percent identity: 45 in 258 aa NP_738301.1 similar to AX065543-1|CAC26011.1| percent identity: 79 in 334 aa NP_738302.1 similar to AX065579-1|CAC26029.1| percent identity: 80 in 322 aa NP_738303.1 converts protoheme IX and farnesyl diphosphate to heme O NP_738304.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_738305.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate NP_738306.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_738307.1 similar to AX074270-2|CAC28458.1| percent identity: 75 in 315 aa NP_738308.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone NP_738309.1 similar to AE008750-11|AAL20090.1| percent identity: 30 in 371 aa NP_738310.1 catalyzes the formation of L-proline from L-ornithine NP_738311.1 similar to AX066815-1|CAC26635.1| percent identity: 71 in 430 aa NP_738312.1 similar to AJ007732-2|CAA07632.1| percent identity: 90 in 77 aa NP_738313.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate NP_738314.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_738315.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_738316.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_738318.1 similar to AF106003-4|AAD42169.1| percent identity: 60 in 328 aa NP_738319.1 similar to AF046871-3|AAC03105.1| percent identity: 35 in 313 aa NP_738320.1 similar to AX066745-1|CAC26600.1| percent identity: 80 in 297 aa NP_738321.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_738322.1 similar to AX064285-1|CAC25383.1| percent identity: 73 in 196 aa NP_738323.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_738324.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_738325.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_738326.1 similar to AX064273-1|CAC25377.1| percent identity: 71 in 328 aa NP_738327.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_738328.1 similar to AL159139-29|CAB76894.1| percent identity: 47 in 456 aa NP_738329.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_738330.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_738331.1 similar to Z80343-9|CAB02483.1| percent identity: 28 in 153 aa NP_738332.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_738333.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_738334.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine NP_738335.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_738336.1 Essential for recycling GMP and indirectly, cGMP NP_738337.1 similar to AL583918-146|CAC30048.1| percent identity: 77 in 103 aa NP_738338.1 OMP decarboxylase; OMPDCase; OMPdecase; type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_738339.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_738340.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_738341.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_738342.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_738343.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity NP_738344.1 similar to D90906-94|BAA17507.1| percent identity: 35 in 299 aa NP_738346.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_738347.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_738348.1 similar to AX065749-1|CAC26114.1| percent identity: 86 in 363 aa NP_738349.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis NP_738350.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_738351.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_738352.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_738353.1 similar to AE004990-1|AAG18867.1| percent identity: 26 in 201 aa NP_738354.1 similar to L41732-4|AAK58497.1| percent identity: 33 in 138 aa NP_738355.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_738356.1 similar to AL583918-126|CAC30022.1| percent identity: 41 in 392 aa NP_738357.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_738358.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_738359.1 similar to AL583918-123|CAC30018.1| percent identity: 68 in 446 aa NP_738362.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_738363.1 similar to AE007099-6|AAK46964.1| percent identity: 46 in 283 aa NP_738364.1 similar to AB056583-2|BAB64333.1| percent identity: 34 in 708 aa NP_738366.1 similar to M11302-1|AAA26834.1| percent identity: 45 in 295 aa NP_738367.1 similar to AE007745-6|AAK80407.1| percent identity: 22 in 221 aa NP_738368.1 similar to AL049707-13|CAB41282.1| percent identity: 73 in 356 aa NP_738369.1 similar to AL049707-12|CAB41281.1| percent identity: 52 in 185 aa NP_738370.1 similar to AE000498-8|AAC77234.1| percent identity: 27 in 203 aa NP_738371.1 similar to AF024666-31|AAG03382.1| percent identity: 84 in 408 aa NP_738373.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_738374.1 similar to AL023591-10|CAA19086.1| percent identity: 36 in 211 aa NP_738375.1 similar to AF170252-1|AAF89695.1| percent identity: 35 in 282 aa NP_738376.1 similar to AY034654-1|AAK58433.1| percent identity: 26 in 106 aa NP_738377.1 similar to AF038651-11|AAC35494.1| percent identity: 93 in 761 aa NP_738378.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_738379.1 similar to AL583918-116|CAC29997.1| percent identity: 29 in 524 aa NP_738380.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_738381.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_738382.1 similar to AF038651-6|AAK19841.1| percent identity: 48 in 120 aa NP_738383.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_738384.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_738385.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_738386.2 similar to AE007101-9|AAK46994.1| percent identity: 71 in 251 aa NP_738387.1 similar to AX066581-1|CAC26518.1| percent identity: 71 in 280 aa NP_738389.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate NP_738390.1 similar to Z96801-7|CAB09631.1| percent identity: 40 in 150 aa NP_738391.1 similar to AE007101-16|AAK47001.1| percent identity: 49 in 363 aa NP_738392.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA NP_738393.1 similar to AX066527-1|CAC26491.1| percent identity: 81 in 217 aa NP_738394.1 similar to AF265558-2|AAG17335.1| percent identity: 56 in 198 aa NP_738395.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_738396.1 similar to AE005301-9|AAG55637.1| percent identity: 34 in 408 aa NP_738397.1 similar to AE002028-2|AAF11440.1| percent identity: 29 in 168 aa NP_738399.2 similar to AX064293-1|CAC25387.1| percent identity: 55 in 226 aa NP_738400.1 similar to AL583922-58|CAC30455.1| percent identity: 22 in 390 aa NP_738401.1 similar to Z80225-44|CAB02327.1| percent identity: 67 in 130 aa NP_738402.1 similar to Z80225-46|CAB02369.1| percent identity: 54 in 233 aa NP_738404.1 similar to Z96072-1|CAB09496.1| percent identity: 55 in 201 aa NP_738405.1 similar to AL023702-16|CAA19240.1| percent identity: 44 in 398 aa NP_738406.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_738407.1 similar to AP001509-125|BAB04406.1| percent identity: 26 in 406 aa NP_738408.1 similar to AL021530-10|CAA16478.1| percent identity: 26 in 236 aa NP_738409.1 catalyzes the formation of dUMP from dUTP NP_738410.1 similar to Z96072-19|CAB09488.1| percent identity: 46 in 149 aa NP_738411.1 similar to AE007106-15|AAK47088.1| percent identity: 54 in 96 aa NP_738412.1 similar to AL583920-122|CAC31405.1| percent identity: 46 in 271 aa NP_738413.1 similar to AF326348-1|AAK15629.1| percent identity: 69 in 241 aa NP_738414.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released NP_738415.1 similar to Z99124-102|CAB16034.1| percent identity: 23 in 405 aa NP_738417.1 similar to AL096852-36|CAB51017.1| percent identity: 54 in 570 aa NP_738418.1 similar to K02372-1|AAA45786.1| percent identity: 29 in 121 aa NP_738419.1 similar to AL035636-7|CAB38482.1| percent identity: 33 in 510 aa NP_738420.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_738421.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase NP_738422.1 similar to L35906-1|AAA91345.1| percent identity: 89 in 228 aa NP_738423.1 similar to M80338-3|AAA23300.1| percent identity: 78 in 328 aa NP_738425.1 similar to Z96072-35|CAB09474.1| percent identity: 46 in 307 aa NP_738426.1 similar to AL353863-6|CAB88936.1| percent identity: 57 in 834 aa NP_738427.1 similar to AF186371-3|AAF06745.1| percent identity: 43 in 313 aa NP_738429.1 similar to AE004217-11|AAF94540.1| percent identity: 48 in 1299 aa NP_738430.2 similar to AE008523-14|AAL00361.1| percent identity: 41 in 156 aa NP_738431.1 similar to AF132735-7|AAF61311.1| percent identity: 21 in 275 aa NP_738433.1 Represses a number of genes involved in the response to DNA damage NP_738434.1 similar to AX065067-1|CAC25773.1| percent identity: 94 in 259 aa NP_738435.1 similar to AL646072-61|CAD16569.1| percent identity: 25 in 320 aa NP_738436.1 similar to AX069150-1|CAC27284.1| percent identity: 78 in 566 aa NP_738437.1 similar to AE007524-3|AAK78098.1| percent identity: 28 in 249 aa NP_738438.1 similar to AL355832-14|CAB90981.1| percent identity: 36 in 324 aa NP_738439.1 similar to AL355832-13|CAB90980.1| percent identity: 45 in 688 aa NP_738440.1 similar to AX151741-1|CAC42595.1| percent identity: 91 in 89 aa NP_738442.1 similar to AX067037-1|CAC26746.1| percent identity: 86 in 429 aa NP_738443.1 similar to U00019-8|AAA17274.1| percent identity: 61 in 461 aa NP_738447.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_738448.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_738450.1 similar to Z98209-10|CAB10907.1| percent identity: 51 in 447 aa NP_738452.1 similar to AX067069-1|CAC26762.1| percent identity: 69 in 219 aa NP_738453.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_738454.1 similar to AL020958-16|CAA15883.1| percent identity: 68 in 242 aa NP_738455.1 similar to X81191-2|CAA57061.1| percent identity: 87 in 293 aa NP_738456.1 similar to AE006406-1|AAK05857.1| percent identity: 35 in 219 aa NP_738457.1 similar to AL020958-13|CAA15880.1| percent identity: 45 in 279 aa NP_738458.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_738459.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_738460.1 similar to AL020958-5|CAA15872.1| percent identity: 37 in 63 aa NP_738461.1 similar to AE001204-6|AAC65216.1| percent identity: 41 in 192 aa NP_738462.1 similar to AX066847-1|CAC26651.1| percent identity: 79 in 227 aa NP_738463.1 similar to AX066853-1|CAC26654.1| percent identity: 74 in 203 aa NP_738464.1 similar to D64002-2|BAA10345.1| percent identity: 23 in 271 aa NP_738465.1 similar to AE008773-18|AAL20582.1| percent identity: 35 in 88 aa NP_738466.1 similar to AL596168-230|CAC96665.1| percent identity: 39 in 150 aa NP_738467.1 similar to AJ312005-1|CAC84779.1| percent identity: 81 in 206 aa NP_738468.1 similar to AE005681-3|AAK22056.1| percent identity: 28 in 92 aa NP_738469.1 similar to AL133422-24|CAB62683.1| percent identity: 48 in 329 aa NP_738471.1 similar to AL031031-5|CAA19851.1| percent identity: 49 in 820 aa NP_738472.1 similar to AL096884-14|CAB51437.1| percent identity: 32 in 208 aa NP_738473.1 similar to X95649-1|CAC19480.1| percent identity: 84 in 700 aa NP_738474.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_738475.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor NP_738476.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_738478.1 similar to Z98741-17|CAB11392.1| percent identity: 68 in 752 aa NP_738479.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_738480.1 similar to AX064805-1|CAC25642.1| percent identity: 85 in 314 aa NP_738481.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_738482.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_738483.1 similar to AX064033-1|CAC25257.1| percent identity: 92 in 218 aa NP_738484.1 similar to AB070940-3|BAB69187.1| percent identity: 47 in 258 aa NP_738485.1 similar to Z81331-41|CAB03650.1| percent identity: 52 in 424 aa NP_738486.1 similar to AE007115-7|AAK47229.1| percent identity: 36 in 311 aa NP_738487.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_738488.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_738489.1 similar to AL591783-9|CAC41675.1| percent identity: 36 in 84 aa NP_738490.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_738491.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_738494.1 similar to AE007174-18|AAK48131.1| percent identity: 49 in 535 aa NP_738495.1 similar to AL391751-3|CAC05748.1| percent identity: 59 in 308 aa NP_738496.1 similar to X56347-3|CAA39789.1| percent identity: 37 in 292 aa NP_738497.1 similar to AE008357-10|AAK90128.1| percent identity: 43 in 561 aa NP_738498.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_738499.1 similar to AL352972-5|CAB88175.1| percent identity: 43 in 232 aa NP_738500.1 similar to AX066019-1|CAC26249.1| percent identity: 80 in 248 aa NP_738501.1 similar to AX066021-1|CAC26250.1| percent identity: 84 in 365 aa NP_738502.1 similar to U13043-5|AAA78897.1| percent identity: 45 in 244 aa NP_738503.1 similar to AL646066-51|CAD15450.1| percent identity: 34 in 480 aa NP_738504.2 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate NP_738505.1 similar to AX066619-1|CAC26537.1| percent identity: 58 in 327 aa NP_738506.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide NP_738510.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation NP_738511.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential NP_738512.1 similar to AL583922-95|CAC30528.1| percent identity: 40 in 592 aa NP_738513.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_738514.1 similar to AL008883-13|CAA15531.1| percent identity: 43 in 400 aa NP_738515.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_738516.1 similar to Z74024-7|CAA98352.1| percent identity: 35 in 87 aa NP_738517.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_738518.1 similar to AL390968-5|CAC01311.1| percent identity: 27 in 119 aa NP_738519.1 similar to AX297999-1|CAD12679.1| percent identity: 83 in 295 aa NP_738520.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_738521.1 Catalyzes the phosphorylation of UMP to UDP NP_738524.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_738525.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_738526.1 similar to AL583917-112|CAC29662.1| percent identity: 29 in 161 aa NP_738527.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_738528.1 similar to AE007119-7|AAK47290.1| percent identity: 41 in 398 aa NP_738529.1 similar to AX065693-1|CAC26086.1| percent identity: 69 in 507 aa NP_738530.1 similar to AL023797-19|CAA19394.1| percent identity: 36 in 120 aa NP_738532.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_738534.1 similar to AE007119-12|AAK47295.1| percent identity: 68 in 101 aa NP_738535.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_738536.1 similar to Z86111-8|CAB06809.1| percent identity: 33 in 266 aa NP_738537.1 similar to AL035707-4|CAB38879.1| percent identity: 43 in 573 aa NP_738538.1 similar to AL591790-86|CAC46872.1| percent identity: 38 in 195 aa NP_738539.1 similar to AE002051-2|AAF11725.1| percent identity: 29 in 442 aa NP_738540.1 similar to AL133213-30|CAB61655.1| percent identity: 29 in 342 aa NP_738541.1 similar to AE001732-1|AAD35656.1| percent identity: 30 in 287 aa NP_738542.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_738543.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate NP_738544.1 similar to D64002-8|BAA10351.1| percent identity: 32 in 355 aa NP_738546.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_738547.1 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate NP_738548.1 similar to AE005046-4|AAG19560.1| percent identity: 43 in 373 aa NP_738549.1 similar to AL049587-26|CAB40693.1| percent identity: 62 in 769 aa NP_738550.1 similar to AX066997-1|CAC26726.1| percent identity: 68 in 615 aa NP_738551.1 similar to AL646076-134|CAD17285.1| percent identity: 26 in 139 aa NP_738554.1 similar to Z95890-25|CAB09338.1| percent identity: 43 in 54 aa NP_738555.1 similar to AL021841-25|CAA17099.1| percent identity: 32 in 387 aa NP_738556.1 similar to X69104-2|CAA48850.1| percent identity: 53 in 300 aa NP_738557.1 similar to X69104-1|CAA48849.1| percent identity: 42 in 116 aa NP_738558.1 similar to Z92539-34|CAB06866.1| percent identity: 69 in 169 aa NP_738559.1 similar to AF143772-5|AAD44203.1| percent identity: 49 in 59 aa NP_738560.1 similar to AF024666-23|AAG03374.1| percent identity: 39 in 192 aa NP_738561.1 similar to D67027-4|BAA11042.1| percent identity: 54 in 119 aa NP_738566.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_738567.1 Essential for efficient processing of 16S rRNA NP_738569.1 similar to AE001797-7|AAD36527.1| percent identity: 31 in 94 aa NP_738570.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_738571.1 similar to BC014743-1|AAH14743.1| percent identity: 35 in 127 aa NP_738572.1 similar to AJ300302-8|CAC22119.1| percent identity: 27 in 241 aa NP_738573.1 similar to AP000004-45|BAA30009.1| percent identity: 40 in 292 aa NP_738574.1 similar to M18263-2|AAA98341.1| percent identity: 34 in 454 aa NP_738575.1 similar to Z97369-5|CAB10614.1| percent identity: 66 in 540 aa NP_738576.1 Uridylylates and de-uridylylates the small trimeric protein Pii NP_738577.1 similar to AE007120-15|AAK47313.1| percent identity: 72 in 112 aa NP_738578.1 similar to AJ010319-2|CAB39372.1| percent identity: 84 in 438 aa NP_738580.1 similar to AE002363-2|AAF40516.1| percent identity: 39 in 400 aa NP_738582.1 similar to AE008485-7|AAK99929.1| percent identity: 28 in 1149 aa NP_738583.1 catalyzes the hydrolysis of acylphosphate NP_738584.1 similar to Z99113-105|CAB13695.1| percent identity: 49 in 473 aa NP_738585.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_738586.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_738587.1 similar to Z74697-13|CAA98983.1| percent identity: 33 in 177 aa NP_738588.1 similar to Z74697-14|CAA98984.1| percent identity: 51 in 227 aa NP_738590.1 similar to AX066737-1|CAC26596.1| percent identity: 57 in 548 aa NP_738591.1 similar to AL034355-14|CAA22219.1| percent identity: 30 in 507 aa NP_738592.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_738593.1 similar to AE004537-6|AAG04441.1| percent identity: 37 in 362 aa NP_738596.1 similar to AX065855-1|CAC26167.1| percent identity: 78 in 418 aa NP_738597.1 similar to AP003585-98|BAB73229.1| percent identity: 42 in 854 aa NP_738598.1 similar to AE008013-4|AAK86611.1| percent identity: 37 in 283 aa NP_738599.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_738600.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_738601.1 similar to AX064147-1|CAC25314.1| percent identity: 63 in 261 aa NP_738602.1 similar to AL096884-11|CAB51434.1| percent identity: 29 in 208 aa NP_738603.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers NP_738604.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_738605.1 similar to AX065167-1|CAC25823.1| percent identity: 76 in 261 aa NP_738606.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis NP_738607.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_738608.1 similar to AE002079-9|AAF12043.1| percent identity: 33 in 388 aa NP_738609.1 similar to AX066381-1|CAC26429.1| percent identity: 75 in 417 aa NP_738611.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis NP_738612.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_738613.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_738617.1 similar to AE007845-3|AAK81402.1| percent identity: 28 in 242 aa NP_738619.1 similar to AF118810-6|AAD19682.1| percent identity: 29 in 181 aa NP_738620.1 similar to AB031392-2|BAA94842.1| percent identity: 60 in 819 aa NP_738621.1 similar to AL109848-25|CAB52849.1| percent identity: 34 in 270 aa NP_738622.1 similar to AX066899-1|CAC26677.1| percent identity: 72 in 339 aa NP_738623.1 similar to AE005056-15|AAG19697.1| percent identity: 27 in 312 aa NP_738624.1 similar to AP003000-197|BAB49852.1| percent identity: 39 in 120 aa NP_738625.1 similar to AE005827-2|AAK23502.1| percent identity: 32 in 209 aa NP_738628.1 similar to AX064859-1|CAC25669.1| percent identity: 78 in 812 aa NP_738629.1 similar to AX064771-1|CAC25625.1| percent identity: 76 in 345 aa NP_738631.1 similar to AX066091-1|CAC26285.1| percent identity: 73 in 346 aa NP_738632.1 similar to AE004932-7|AAG08580.1| percent identity: 32 in 125 aa NP_738634.1 similar to AX065737-1|CAC26108.1| percent identity: 75 in 211 aa NP_738635.1 similar to AX064863-1|CAC25671.1| percent identity: 73 in 577 aa NP_738636.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic NP_738638.1 similar to AX244117-1|CAC88537.1| percent identity: 84 in 401 aa NP_738639.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_738640.1 similar to AJ414159-51|CAC93304.1| percent identity: 38 in 284 aa NP_738642.1 similar to AL596170-166|CAC97187.1| percent identity: 36 in 306 aa NP_738643.1 similar to Z74020-4|CAA98323.1| percent identity: 41 in 171 aa NP_738645.1 similar to AX065651-1|CAC26065.1| percent identity: 72 in 543 aa NP_738647.1 similar to AF263011-5|AAF81232.1| percent identity: 40 in 298 aa NP_738648.1 similar to AL049754-12|CAB42021.1| percent identity: 33 in 544 aa NP_738649.1 similar to AX063843-1|CAC25163.1| percent identity: 77 in 318 aa NP_738650.2 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_738651.1 similar to AE004565-8|AAG04749.1| percent identity: 33 in 272 aa NP_738653.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_738655.1 similar to AJ242594-1|CAB69044.2| percent identity: 74 in 351 aa NP_738656.1 similar to AP001515-282|BAB06267.1| percent identity: 29 in 96 aa NP_738657.1 similar to Y08964-6|CAB66327.1| percent identity: 72 in 155 aa NP_738658.1 similar to AL109663-13|CAB51989.1| percent identity: 39 in 231 aa NP_738659.1 similar to AB003132-4|BAA21688.1| percent identity: 83 in 244 aa NP_738660.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_738661.1 similar to AB015023-2|BAA34294.1| percent identity: 64 in 222 aa NP_738662.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_738663.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_738664.1 similar to Z95388-24|CAB08673.1| percent identity: 37 in 515 aa NP_738665.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_738666.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_738667.1 similar to AE007068-17|AAK46500.1| percent identity: 52 in 491 aa NP_738668.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_738669.1 similar to AB041009-1|BAB15945.1| percent identity: 77 in 714 aa NP_738671.1 similar to Z95388-35|CAB08662.1| percent identity: 54 in 327 aa NP_738672.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_738673.1 similar to AX005491-1|CAC05099.1| percent identity: 40 in 132 aa NP_738675.1 similar to AL022602-13|CAA18679.1| percent identity: 31 in 184 aa NP_738676.1 similar to AY045759-3|AAK98793.1| percent identity: 45 in 295 aa NP_738677.1 similar to AL109962-34|CAB53152.1| percent identity: 41 in 357 aa NP_738678.1 similar to AL021184-6|CAA15989.1| percent identity: 29 in 518 aa NP_738679.1 similar to AE007069-13|AAK46516.1| percent identity: 44 in 122 aa NP_738680.1 similar to AL079308-18|CAB45215.1| percent identity: 30 in 669 aa NP_738681.1 similar to AE007070-5|AAK46522.1| percent identity: 33 in 408 aa NP_738682.1 similar to AL583920-43|CAC31274.1| percent identity: 28 in 410 aa NP_738683.1 similar to AF056968-1|AAC13561.1| percent identity: 66 in 462 aa NP_738684.1 similar to AL022602-20|CAA18687.1| percent identity: 59 in 163 aa NP_738685.1 similar to AL583922-58|CAC30455.1| percent identity: 32 in 415 aa NP_738686.1 similar to AE005321-4|AAG55861.1| percent identity: 21 in 360 aa NP_738687.1 similar to AX066535-1|CAC26495.1| percent identity: 70 in 243 aa NP_738688.1 similar to AF096280-1|AAF80161.1| percent identity: 68 in 319 aa NP_738689.1 similar to AL355913-5|CAB91117.1| percent identity: 48 in 375 aa NP_738690.1 similar to AX065253-1|CAC25866.1| percent identity: 62 in 306 aa NP_738691.1 similar to AL583920-35|CAC31266.1| percent identity: 42 in 134 aa NP_738692.1 similar to AJ306418-4|CAC33828.1| percent identity: 87 in 536 aa NP_738693.1 similar to AJ306418-3|CAC33827.1| percent identity: 86 in 408 aa NP_738694.1 similar to AX065617-1|CAC26048.1| percent identity: 89 in 296 aa NP_738695.1 similar to AX065537-1|CAC26008.1| percent identity: 91 in 217 aa NP_738696.1 similar to AE007071-10|AAK46541.1| percent identity: 36 in 143 aa NP_738697.1 similar to AB052749-1|BAB64407.1| percent identity: 85 in 359 aa NP_738698.1 similar to AB029550-1|BAA89484.1| percent identity: 87 in 640 aa NP_738699.1 similar to AL049497-34|CAB39888.1| percent identity: 71 in 118 aa NP_738700.1 similar to AE007072-4|AAK46548.1| percent identity: 36 in 242 aa NP_738701.1 similar to AX064555-1|CAC25517.1| percent identity: 62 in 174 aa NP_738702.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole NP_738703.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole NP_738704.1 similar to AE006951-16|AAK44725.1| percent identity: 56 in 234 aa NP_738705.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_738706.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_738707.1 similar to AX065833-1|CAC26156.1| percent identity: 89 in 129 aa NP_738708.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA NP_738709.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein NP_738710.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_738711.1 similar to AX066609-1|CAC26532.1| percent identity: 86 in 259 aa NP_738712.1 similar to AX066613-1|CAC26534.1| percent identity: 74 in 542 aa NP_738713.1 similar to AL355740-5|CAB90844.1| percent identity: 39 in 150 aa NP_738714.1 similar to AF005635-1|AAD01244.2| percent identity: 90 in 477 aa NP_738715.1 similar to AL357613-26|CAB93754.1| percent identity: 33 in 274 aa NP_738718.1 similar to AJ276511-1|CAC06383.1| percent identity: 22 in 148 aa NP_738721.1 similar to AL031107-28|CAA19957.1| percent identity: 35 in 106 aa NP_738722.1 similar to U67315-4|AAC45210.1| percent identity: 28 in 241 aa NP_738723.1 similar to AE000066-6|AAB91627.1| percent identity: 29 in 475 aa NP_738725.1 catalyzes the formation of L-proline from L-ornithine NP_738726.1 similar to AF050112-1|AAC28311.1| percent identity: 65 in 474 aa NP_738729.1 similar to AE004549-2|AAG04575.1| percent identity: 35 in 315 aa NP_738730.1 similar to AL591783-72|CAC41738.1| percent identity: 46 in 286 aa NP_738731.1 similar to AP000003-255|BAA29948.1| percent identity: 34 in 109 aa NP_738732.2 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_738734.1 similar to AX065335-1|CAC25907.1| percent identity: 69 in 409 aa NP_738736.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme NP_738737.1 similar to AL136500-3|CAB66175.1| percent identity: 61 in 447 aa NP_738738.1 similar to AL049841-39|CAB42785.1| percent identity: 27 in 322 aa NP_738739.1 similar to AB058959-1|BAB40711.1| percent identity: 19 in 503 aa NP_738742.1 similar to AP002994-32|BAB47713.1| percent identity: 35 in 452 aa NP_738743.1 similar to AX064919-1|CAC25699.1| percent identity: 75 in 391 aa NP_738744.1 similar to Z70692-10|CAA94652.1| percent identity: 29 in 236 aa NP_738745.1 similar to AX065379-1|CAC25929.1| percent identity: 77 in 376 aa NP_738746.1 similar to AL591978-45|CAC99247.1| percent identity: 27 in 357 aa NP_738747.1 similar to AX065507-1|CAC25993.1| percent identity: 71 in 215 aa NP_738748.1 similar to AE007074-3|AAK46577.1| percent identity: 55 in 153 aa NP_738749.1 similar to AL023635-21|CAA19213.1| percent identity: 41 in 255 aa NP_738750.1 similar to AY033235-1|AAK67495.1| percent identity: 43 in 305 aa NP_738751.1 similar to Z70692-20|CAA94660.1| percent identity: 51 in 130 aa NP_738753.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC NP_738754.1 similar to AF162694-1|AAF86640.1| percent identity: 50 in 266 aa NP_738755.1 similar to AE004191-4|AAF94261.1| percent identity: 49 in 288 aa NP_738756.1 similar to AX065377-1|CAC25928.1| percent identity: 87 in 331 aa NP_738758.1 similar to AX065915-1|CAC26197.1| percent identity: 67 in 316 aa NP_738759.1 similar to AX023832-1|CAC08867.1| percent identity: 32 in 76 aa NP_738760.1 similar to AX065037-1|CAC25758.1| percent identity: 88 in 272 aa NP_738761.1 similar to AE001968-4|AAF10764.1| percent identity: 33 in 273 aa NP_738763.1 similar to AL583923-73|CAC30735.1| percent identity: 52 in 269 aa NP_738770.1 similar to AL583945-5|CAC32341.1| percent identity: 34 in 215 aa NP_738774.1 similar to AE007104-12|AAK47050.1| percent identity: 23 in 412 aa NP_738775.1 similar to AJ278740-1|CAC48066.1| percent identity: 35 in 537 aa NP_738776.1 similar to X69164-1|CAA48914.1| percent identity: 25 in 171 aa NP_738777.1 similar to AX065255-1|CAC25867.1| percent identity: 80 in 606 aa NP_738778.1 similar to AL160371-59|CAC59893.1| percent identity: 29 in 67 aa NP_738779.1 synthesizes RNA primers at the replication forks NP_738780.1 similar to M88615-1|AAA26806.1| percent identity: 35 in 152 aa NP_738782.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_738783.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate NP_738784.1 similar to AL591983-121|CAD00520.1| percent identity: 28 in 167 aa NP_738785.1 similar to Z83860-12|CAB06160.1| percent identity: 31 in 634 aa NP_738788.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_738789.1 similar to AE000934-3|AAB86261.1| percent identity: 29 in 99 aa NP_738790.1 similar to AE000739-6|AAC07373.1| percent identity: 30 in 138 aa NP_738791.1 similar to AJ248288-93|CAB50539.1| percent identity: 26 in 342 aa NP_738792.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_738793.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_738794.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_738795.1 similar to AE001751-7|AAD35927.1| percent identity: 28 in 433 aa NP_738796.1 similar to AL136534-6|CAB66427.1| percent identity: 49 in 175 aa NP_738797.1 similar to AE002037-2|AAF11540.1| percent identity: 49 in 331 aa NP_738798.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_738799.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_738800.2 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_738801.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_738805.1 similar to AX066477-1|CAC26466.1| percent identity: 81 in 613 aa NP_738806.1 similar to AX065283-1|CAC25881.1| percent identity: 77 in 708 aa NP_738807.1 similar to AX066759-1|CAC26607.1| percent identity: 79 in 621 aa NP_738808.2 similar to X99632-1|CAA67953.1| percent identity: 52 in 415 aa NP_738809.1 similar to AP003131-183|BAB41925.1| percent identity: 33 in 102 aa NP_738810.1 similar to AX067031-1|CAC26743.1| percent identity: 72 in 492 aa NP_738811.1 similar to AL049573-25|CAB40333.1| percent identity: 44 in 125 aa NP_738813.1 similar to AE008766-3|AAL20431.1| percent identity: 39 in 674 aa NP_738814.1 similar to AL357432-31|CAB93058.1| percent identity: 34 in 253 aa NP_738815.1 similar to AE006925-6|AAK44358.1| percent identity: 65 in 572 aa NP_738816.1 similar to AX064873-1|CAC25676.1| percent identity: 60 in 361 aa NP_738817.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate NP_738821.1 similar to Z93934-1|CAB07924.1| percent identity: 33 in 368 aa NP_738822.1 similar to M89931-2|AAC18909.1| percent identity: 72 in 423 aa NP_738823.1 similar to AX066083-1|CAC26281.1| percent identity: 84 in 325 aa NP_738826.1 similar to AP003584-112|BAB72959.1| percent identity: 31 in 122 aa NP_738827.1 similar to AJ001436-1|CAA04760.1| percent identity: 84 in 613 aa NP_738828.1 similar to AB062679-1|BAB78520.1| percent identity: 23 in 314 aa NP_738829.1 similar to M57500-3|AAC64901.1| percent identity: 72 in 602 aa NP_738831.1 similar to AL589164-19|CAC33058.1| percent identity: 41 in 308 aa NP_738832.1 similar to AX065005-1|CAC25742.1| percent identity: 78 in 951 aa NP_738833.1 similar to AP003011-45|BAB53305.1| percent identity: 27 in 225 aa NP_738834.1 similar to AE008242-1|AAK89002.1| percent identity: 33 in 497 aa NP_738835.1 similar to AF242881-66|AAB88467.1| percent identity: 35 in 310 aa NP_738836.1 similar to AX067063-1|CAC26759.1| percent identity: 79 in 270 aa NP_738837.1 similar to AE008344-7|AAK90012.1| percent identity: 45 in 480 aa NP_738838.1 similar to AL357524-20|CAB93412.1| percent identity: 37 in 182 aa NP_738839.1 similar to AL353864-16|CAB88967.1| percent identity: 44 in 310 aa NP_738840.1 similar to AE004955-1|AAG08807.1| percent identity: 27 in 241 aa NP_738841.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA NP_738842.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates NP_738843.1 similar to AL603643-93|CAC48784.1| percent identity: 28 in 175 aa NP_738849.1 similar to AL627279-198|CAD09572.1| percent identity: 48 in 435 aa NP_738850.1 similar to AY054120-25|AAL17939.1| percent identity: 30 in 163 aa NP_738851.1 similar to AE008889-10|AAL22894.1| percent identity: 30 in 322 aa NP_738852.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_738853.1 similar to Z81368-21|CAB03722.1| percent identity: 50 in 125 aa NP_738854.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_738855.1 similar to AX063725-1|CAC25103.1| percent identity: 74 in 222 aa NP_738856.1 similar to AF001355-3|AAC61658.1| percent identity: 29 in 145 aa NP_738857.1 required for the assembly and function of the DNAX complex which are required fro the assembly of the beta subunit onto primed DNA NP_738858.1 similar to AL136518-5|CAB66245.1| percent identity: 27 in 511 aa NP_738859.1 similar to L15202-2|AAC36905.1| percent identity: 32 in 202 aa NP_738860.1 similar to AL583923-160|CAC30880.1| percent identity: 37 in 223 aa NP_738861.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_738863.1 similar to AE007087-14|AAK46787.1| percent identity: 35 in 258 aa NP_738864.1 similar to AX064297-1|CAC25389.1| percent identity: 78 in 235 aa NP_738865.1 similar to AX064309-1|CAC25395.1| percent identity: 80 in 157 aa NP_738867.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_738870.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_738873.1 similar to AE007007-6|AAK45589.1| percent identity: 28 in 393 aa NP_738874.1 similar to U31230-3|AAC44175.1| percent identity: 71 in 290 aa NP_738875.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_738876.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_738877.1 similar to AX067041-1|CAC26748.1| percent identity: 86 in 628 aa NP_738878.1 similar to AX064577-1|CAC25528.1| percent identity: 72 in 305 aa NP_738880.1 involved in the peptidyltransferase reaction during translation NP_738881.1 similar to AE001872-2|AAF09679.1| percent identity: 43 in 101 aa NP_738882.1 similar to AL139298-10|CAB75380.1| percent identity: 39 in 1063 aa NP_738885.1 similar to AL121600-8|CAB56728.1| percent identity: 57 in 338 aa NP_738886.1 similar to AE005496-5|AAG57782.1| percent identity: 35 in 144 aa NP_738887.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_738889.1 similar to AL512944-21|CAC22738.1| percent identity: 36 in 82 aa NP_738890.1 similar to AX064445-1|CAC25463.1| percent identity: 72 in 144 aa NP_738891.1 similar to AX064415-1|CAC25448.1| percent identity: 83 in 494 aa NP_738892.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_738894.1 similar to AX066119-1|CAC26299.1| percent identity: 66 in 459 aa NP_738895.1 catalyzes the oxidation of malate to oxaloacetate NP_738896.1 similar to PIR:AG2063 percent identity: 29 in 42 aa NP_738897.1 similar to AE009242-5|AAL43931.1| percent identity: 30 in 202 aa NP_738898.1 similar to AL589164-19|CAC33058.1| percent identity: 38 in 306 aa NP_738900.1 similar to AE005854-5|AAK23772.1| percent identity: 27 in 375 aa NP_738901.1 binds and unfolds substrates as part of the ClpXP protease NP_738902.1 similar to AF109386-2|AAD40813.1| percent identity: 62 in 214 aa NP_738903.1 similar to M80534-1|AAA31019.1| percent identity: 54 in 252 aa NP_738904.1 similar to AE008232-10|AAK88897.1| percent identity: 42 in 261 aa NP_738905.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation NP_738906.1 similar to AX064187-1|CAC25334.1| percent identity: 80 in 251 aa NP_738907.1 similar to AL137165-20|CAB69684.1| percent identity: 27 in 328 aa NP_738908.1 similar to AF003947-5|AAC38246.1| percent identity: 69 in 126 aa NP_738909.1 similar to Y10223-1|CAA71270.1| percent identity: 34 in 357 aa NP_738910.1 similar to AX066073-1|CAC26276.1| percent identity: 79 in 204 aa NP_738911.1 similar to AF230650-1|AAG27523.1| percent identity: 49 in 229 aa NP_738912.1 similar to AF144091-2|AAD41808.1| percent identity: 55 in 92 aa NP_738913.2 similar to X99622-6|CAA67934.1| percent identity: 59 in 373 aa NP_738914.1 similar to AX066055-1|CAC26267.1| percent identity: 92 in 286 aa NP_738915.1 similar to AX066065-1|CAC26272.1| percent identity: 86 in 498 aa NP_738916.1 similar to AB055706-2|BAB70699.1| percent identity: 69 in 168 aa NP_738917.1 with BenAB catalyzes the formation of 2-hydro-1,2-dihydroxybenzoate from benzoate NP_738918.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol NP_738919.1 similar to U95170-1|AAD28307.1| percent identity: 23 in 862 aa NP_738920.1 similar to AF279141-5|AAK58907.1| percent identity: 57 in 451 aa NP_738921.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_738922.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_738923.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_738928.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity NP_738929.1 similar to AX065389-1|CAC25934.1| percent identity: 74 in 206 aa NP_738930.1 similar to AL583922-49|CAC30436.1| percent identity: 49 in 847 aa NP_738931.1 similar to AB006424-67|BAA33134.1| percent identity: 28 in 232 aa NP_738933.1 similar to X53013-1|CAA37193.1| percent identity: 29 in 133 aa NP_738934.1 similar to AL031155-5|CAA20068.1| percent identity: 48 in 125 aa NP_738935.1 similar to X69104-2|CAA48850.1| percent identity: 89 in 64 aa NP_738936.1 similar to AL442120-13|CAC09545.1| percent identity: 24 in 420 aa NP_738937.1 similar to AE007110-9|AAK47145.1| percent identity: 72 in 531 aa NP_738938.1 similar to AE000868-14|AAB85439.1| percent identity: 29 in 283 aa NP_738939.1 similar to X99719-5|CAA68059.1| percent identity: 26 in 1063 aa NP_738940.1 similar to AJ414152-49|CAC91165.1| percent identity: 24 in 282 aa NP_738941.1 similar to AF176664-6|AAG09260.1| percent identity: 43 in 548 aa NP_738942.1 similar to U64514-3|AAB41690.1| percent identity: 38 in 287 aa NP_738943.1 similar to AF058302-2|AAC18097.1| percent identity: 40 in 306 aa NP_738944.1 similar to AX066437-1|CAC26446.1| percent identity: 75 in 547 aa NP_738946.1 similar to AX244017-1|CAC88487.1| percent identity: 73 in 452 aa NP_738947.1 similar to AX065187-1|CAC25833.1| percent identity: 66 in 236 aa NP_738948.1 similar to Y16103-1|CAA76068.1| percent identity: 24 in 214 aa NP_738952.1 similar to X14884-1|CAA33023.1| percent identity: 34 in 212 aa NP_738953.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine NP_738954.1 similar to AE007130-17|AAK47456.1| percent identity: 38 in 260 aa NP_738955.1 similar to AE009186-6|AAL43368.1| percent identity: 33 in 130 aa NP_738956.1 similar to AP001509-12|BAB04293.1| percent identity: 42 in 375 aa NP_738958.1 similar to AE005058-12|AAG19726.1| percent identity: 34 in 127 aa NP_738959.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence NP_738960.1 similar to U64095-1|AAB57885.1| percent identity: 18 in 211 aa NP_738961.1 similar to Z74410-19|CAA98938.1| percent identity: 29 in 673 aa NP_738964.1 similar to AP003363-289|BAB58078.1| percent identity: 39 in 450 aa NP_738966.1 similar to AE001466-7|AAD05872.1| percent identity: 68 in 291 aa NP_738967.1 similar to AL646063-159|CAD15008.1| percent identity: 35 in 335 aa NP_738968.1 similar to AE001722-11|AAD35527.1| percent identity: 32 in 412 aa NP_738969.1 similar to AP003585-112|BAB73243.1| percent identity: 38 in 270 aa NP_738970.1 similar to U67473-9|AAB98147.1| percent identity: 37 in 219 aa NP_738971.1 similar to AE007592-11|AAK78750.1| percent identity: 31 in 389 aa NP_738972.1 similar to AL591974-85|CAD00807.1| percent identity: 52 in 170 aa NP_738973.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates NP_738975.1 similar to BC017895-1|AAH17895.1| percent identity: 33 in 42 aa NP_738978.1 similar to L36817-2|AAC41420.1| percent identity: 42 in 250 aa NP_738979.1 similar to AL583918-86|CAC29937.1| percent identity: 50 in 265 aa NP_738980.1 3'-5' exoribonuclease specific for small oligoribonuclotides NP_738981.1 similar to U97227-1|AAC46181.1| percent identity: 26 in 392 aa NP_738982.1 similar to AL583918-84|CAC29934.1| percent identity: 44 in 397 aa NP_738985.1 catalyzes the formation of glutamate from glutamine NP_738986.1 similar to AL591793-190|CAC47885.1| percent identity: 28 in 360 aa NP_738987.2 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism NP_738988.1 similar to AL627270-179|CAD01805.1| percent identity: 38 in 422 aa NP_738989.1 similar to AJ298137-2|CAC43287.1| percent identity: 46 in 455 aa NP_738990.1 similar to X84105-1|CAA58911.1| percent identity: 51 in 140 aa NP_738991.1 similar to D90805-5|BAA15367.1| percent identity: 38 in 246 aa NP_738992.1 similar to AX065307-1|CAC25893.1| percent identity: 56 in 156 aa NP_738994.1 similar to AL646059-60|CAD13969.1| percent identity: 41 in 147 aa NP_738995.1 similar to AL096852-18|CAB50999.1| percent identity: 50 in 185 aa NP_738997.1 similar to AL583918-82|CAC29932.1| percent identity: 60 in 155 aa NP_738998.1 similar to AP003007-93|BAB52091.1| percent identity: 29 in 205 aa NP_738999.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_739000.1 similar to Z99105-96|CAB12061.1| percent identity: 36 in 474 aa NP_739001.1 similar to AE004526-1|AAG04306.1| percent identity: 28 in 290 aa NP_739002.1 similar to X64795-1|CAA46024.1| percent identity: 62 in 2997 aa NP_739003.1 similar to AL445963-25|CAC14380.1| percent identity: 64 in 139 aa NP_739005.1 similar to AP001520-121|BAB07616.1| percent identity: 33 in 316 aa NP_739006.1 similar to AL646070-121|CAD16225.1| percent identity: 42 in 148 aa NP_739007.1 similar to AL583917-112|CAC29662.1| percent identity: 39 in 181 aa NP_739008.1 similar to U00014-2|AAA50903.1| percent identity: 42 in 94 aa NP_739009.1 similar to AF099925-4|AAC69502.2| percent identity: 22 in 144 aa NP_739010.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_739011.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_739012.1 similar to AL079348-8|CAB45464.1| percent identity: 33 in 255 aa NP_739013.1 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_739015.1 similar to AL355832-22|CAB90989.1| percent identity: 43 in 146 aa NP_739016.1 similar to AX065075-1|CAC25777.1| percent identity: 69 in 248 aa NP_739017.1 similar to AL583921-7|CAC31548.1| percent identity: 44 in 310 aa NP_739018.1 similar to AF043091-1|AAD02257.1| percent identity: 24 in 279 aa NP_739019.1 similar to AL583921-6|CAC31547.1| percent identity: 32 in 180 aa NP_739020.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA NP_739022.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate NP_739024.1 similar to AF187306-1|AAF25828.1| percent identity: 23 in 390 aa NP_739025.1 similar to AE003927-11|AAF83692.1| percent identity: 31 in 656 aa NP_739026.1 similar to AL023517-6|CAA18980.1| percent identity: 41 in 221 aa NP_739027.1 similar to AX063871-1|CAC25177.1| percent identity: 87 in 415 aa NP_739028.1 similar to AB052748-2|BAB64406.1| percent identity: 95 in 565 aa NP_739029.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_739030.1 similar to AE001770-16|AAD36204.1| percent identity: 37 in 162 aa NP_739032.1 similar to AJ003022-2|CAA05808.1| percent identity: 34 in 227 aa NP_739033.1 Catalyzes the rate-limiting step in dNTP synthesis NP_739034.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_739035.1 similar to AF112535-1|AAD41034.1| percent identity: 85 in 77 aa NP_739037.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif NP_739038.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_739039.1 similar to AE008757-17|AAL20249.1| percent identity: 30 in 230 aa NP_739040.1 similar to AL109962-23|CAB53141.1| percent identity: 28 in 135 aa NP_739041.1 similar to M80458-1|AAA23407.1| percent identity: 45 in 321 aa NP_739043.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate NP_739044.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_739046.1 similar to AL442120-19|CAC09551.1| percent identity: 30 in 848 aa NP_739047.1 similar to AX066863-1|CAC26659.1| percent identity: 87 in 235 aa NP_739049.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_739053.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_739054.1 similar to Z73419-32|CAA97747.1| percent identity: 68 in 190 aa NP_739055.1 similar to AL035478-15|CAB36602.1| percent identity: 46 in 273 aa NP_739056.1 similar to AX063963-1|CAC25222.1| percent identity: 88 in 311 aa NP_739057.1 similar to AE007583-11|AAK78664.1| percent identity: 58 in 182 aa NP_739058.1 similar to AL512944-21|CAC22738.1| percent identity: 32 in 95 aa NP_739059.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_739060.1 catalyzes the interconversion of succinyl-CoA and succinate NP_739061.1 similar to AF325035-1|AAG40387.1| percent identity: 29 in 152 aa NP_739062.1 similar to AX066439-1|CAC26447.1| percent identity: 69 in 244 aa NP_739063.1 similar to AL646069-92|CAD16026.1| percent identity: 36 in 273 aa NP_739064.1 similar to AE006309-6|AAK04857.1| percent identity: 29 in 289 aa NP_739065.1 similar to AF107019-1|AAD28828.1| percent identity: 26 in 435 aa NP_739066.1 similar to AE006309-6|AAK04857.1| percent identity: 28 in 293 aa NP_739067.1 similar to AF019629-1|AAC13545.1| percent identity: 25 in 500 aa NP_739069.1 similar to AP001513-30|BAB05476.1| percent identity: 35 in 420 aa NP_739070.1 similar to AE009010-7|AAL41417.1| percent identity: 45 in 503 aa NP_739071.1 similar to AX065971-1|CAC26225.1| percent identity: 92 in 381 aa NP_739072.1 similar to AE007148-14|AAK47743.1| percent identity: 38 in 215 aa NP_739074.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_739075.1 similar to Z95209-3|CAB08490.1| percent identity: 48 in 296 aa NP_739076.1 similar to AJ243674-5|CAB65970.1| percent identity: 48 in 334 aa NP_739077.1 similar to AX065997-1|CAC26238.1| percent identity: 75 in 373 aa NP_739078.1 similar to AL022004-11|CAA17625.1| percent identity: 36 in 274 aa NP_739080.1 similar to AX066359-1|CAC26418.1| percent identity: 65 in 366 aa NP_739081.1 similar to AL022004-5|CAA17619.1| percent identity: 48 in 216 aa NP_739082.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate NP_739083.1 similar to AB003158-6|BAA89441.1| percent identity: 57 in 339 aa NP_739084.1 similar to AL022004-2|CAA17616.1| percent identity: 56 in 65 aa NP_739085.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_739086.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_739087.1 similar to AX064809-1|CAC25644.1| percent identity: 68 in 125 aa NP_739088.1 similar to AB003158-2|BAA89437.1| percent identity: 73 in 325 aa NP_739089.1 similar to AL591857-1|CAC40591.1| percent identity: 36 in 238 aa NP_739090.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_739091.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_739092.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway NP_739093.1 similar to AB010691-9|BAA37105.1| percent identity: 43 in 157 aa NP_739094.1 similar to L76304-1|AAB39273.1| percent identity: 26 in 801 aa NP_739095.1 similar to AX064515-1|CAC25497.1| percent identity: 76 in 224 aa NP_739096.1 similar to AP003594-221|BAB75610.1| percent identity: 43 in 697 aa NP_739097.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_739098.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_739099.1 similar to AE009094-13|AAL42340.1| percent identity: 42 in 379 aa NP_739100.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_739102.1 similar to AL583924-133|CAC31193.1| percent identity: 52 in 132 aa NP_739103.1 similar to AE006988-14|AAK45313.1| percent identity: 29 in 466 aa NP_739104.1 similar to AE006988-15|AAK45314.1| percent identity: 47 in 232 aa NP_739105.1 similar to AX066327-1|CAC26402.1| percent identity: 70 in 479 aa NP_739106.1 similar to AL591793-205|CAC47900.1| percent identity: 27 in 431 aa NP_739107.1 similar to AE006941-4|AAK44573.1| percent identity: 28 in 141 aa NP_739108.1 similar to AX063759-1|CAC25121.1| percent identity: 85 in 320 aa NP_739109.1 similar to AE004490-12|AAG03932.1| percent identity: 36 in 266 aa NP_739110.1 similar to AE007448-11|AAK75626.1| percent identity: 24 in 287 aa NP_739112.1 similar to AF218267-10|AAF63453.1| percent identity: 32 in 385 aa NP_739113.1 similar to AP002999-292|BAB49607.1| percent identity: 44 in 103 aa NP_739116.1 similar to AF326510-1|AAK61331.1| percent identity: 78 in 475 aa NP_739118.1 similar to AX063735-1|CAC25109.1| percent identity: 82 in 478 aa NP_739120.1 similar to AX064857-1|CAC25668.1| percent identity: 70 in 254 aa NP_739121.1 similar to Z92774-21|CAB07149.1| percent identity: 44 in 355 aa NP_739122.1 similar to AL583918-43|CAC29845.1| percent identity: 28 in 289 aa NP_739123.1 similar to AX066889-1|CAC26672.1| percent identity: 73 in 229 aa NP_739124.1 similar to AP001511-279|BAB05109.1| percent identity: 28 in 265 aa NP_739125.1 similar to Z92774-25|CAB07153.1| percent identity: 62 in 310 aa NP_739126.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_739127.1 similar to A72152-1|CAB42722.1| percent identity: 25 in 383 aa NP_739128.1 similar to AX065297-1|CAC25888.1| percent identity: 69 in 253 aa NP_739129.1 similar to AL603643-87|CAC48778.1| percent identity: 25 in 218 aa NP_739130.2 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_739131.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_739132.1 similar to AE007169-13|AAK48047.1| percent identity: 75 in 157 aa NP_739134.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_739135.1 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair NP_739136.1 similar to AL583923-154|CAC30873.1| percent identity: 25 in 230 aa NP_739137.1 similar to AX065825-1|CAC26152.1| percent identity: 76 in 206 aa NP_739138.1 similar to AF121797-1|AAD21076.1| percent identity: 46 in 293 aa NP_739139.1 similar to AX065705-1|CAC26092.1| percent identity: 92 in 926 aa NP_739140.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_739141.1 similar to AX066097-1|CAC26288.1| percent identity: 79 in 473 aa NP_739143.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_739144.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_739148.1 similar to AX064503-1|CAC25491.1| percent identity: 77 in 159 aa NP_739149.1 similar to AL583917-157|CAC29733.1| percent identity: 53 in 129 aa NP_739150.1 similar to AX064487-1|CAC25483.1| percent identity: 81 in 284 aa NP_739151.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_739152.1 similar to AF037269-1|AAC32257.1| percent identity: 56 in 741 aa NP_739153.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively NP_739154.1 similar to AE007172-3|AAK48088.1| percent identity: 42 in 285 aa NP_739155.1 similar to Z95436-9|CAB08829.1| percent identity: 41 in 414 aa NP_739156.1 Catalyzes the hydrolysis of pyrophosphate NP_739157.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine NP_739158.1 similar to AL646084-18|CAD18448.1| percent identity: 28 in 141 aa NP_739161.1 similar to Z77724-30|CAB01278.1| percent identity: 44 in 199 aa NP_739163.1 similar to X81894-2|CAA57483.1| percent identity: 28 in 392 aa NP_739167.1 similar to AP002998-234|BAB49212.1| percent identity: 26 in 1276 aa NP_739168.1 similar to AE009012-9|AAL41438.1| percent identity: 52 in 270 aa NP_739171.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_739174.1 similar to AL049478-8|CAB39573.1| percent identity: 37 in 448 aa NP_739177.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_739178.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_739179.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone NP_739180.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport NP_739181.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_739182.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali NP_739184.1 ATP-dependent carboxylate-amine ligase NP_739187.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_739188.1 similar to AE006947-17|AAK44666.1| percent identity: 34 in 318 aa NP_739189.1 similar to AE004013-1|AAF84735.1| percent identity: 38 in 261 aa NP_739190.1 similar to AX297997-1|CAD12678.1| percent identity: 78 in 500 aa NP_739191.1 similar to Z99107-15|CAB12387.1| percent identity: 33 in 383 aa NP_739192.1 similar to AX066929-1|CAC26692.1| percent identity: 61 in 413 aa NP_739193.1 similar to AL359152-36|CAB94563.1| percent identity: 26 in 254 aa NP_739194.1 similar to AL359152-39|CAB94566.1| percent identity: 59 in 312 aa NP_739195.1 similar to Z84724-7|CAB06583.1| percent identity: 53 in 165 aa NP_739197.1 similar to AE006946-13|AAK44649.1| percent identity: 35 in 420 aa NP_739198.1 similar to AX063823-1|CAC25153.1| percent identity: 59 in 346 aa NP_739199.1 similar to AL583918-25|CAC29812.1| percent identity: 39 in 821 aa NP_739200.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_739201.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_739202.1 similar to AE001908-11|AAF10073.1| percent identity: 42 in 465 aa NP_739204.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis NP_739205.1 similar to AX064083-1|CAC25282.1| percent identity: 38 in 391 aa NP_739207.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_739208.1 similar to U23181-6|AAC48204.1| percent identity: 20 in 247 aa NP_739210.1 similar to X17313-3|CAA35192.1| percent identity: 74 in 359 aa NP_739211.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_739212.1 similar to AL596166-86|CAC95995.1| percent identity: 24 in 386 aa NP_739213.1 similar to AL021931-15|CAA17386.1| percent identity: 77 in 182 aa NP_739214.2 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_739216.1 similar to AL646068-185|CAD15933.1| percent identity: 37 in 278 aa NP_739218.1 similar to U43535-1|AAB51443.1| percent identity: 67 in 461 aa NP_739223.1 similar to U43536-1|AAB49540.1| percent identity: 90 in 850 aa NP_739225.1 similar to AF132735-7|AAF61311.1| percent identity: 21 in 275 aa NP_739226.1 similar to AL603642-87|CAC48487.1| percent identity: 31 in 138 aa NP_739228.1 similar to L09108-1|AAA25861.1| percent identity: 46 in 98 aa NP_739229.1 similar to Z81011-3|CAB02647.1| percent identity: 43 in 279 aa NP_739230.1 similar to AE009275-8|AAL44264.1| percent identity: 26 in 262 aa NP_739232.1 similar to AE006951-12|AAK44721.1| percent identity: 46 in 268 aa NP_739235.1 similar to AX065091-1|CAC25785.1| percent identity: 93 in 506 aa NP_739236.1 similar to AL583925-135|CAC32010.1| percent identity: 58 in 114 aa NP_739237.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_739238.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_739239.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_739245.1 similar to AL391754-3|CAC05875.1| percent identity: 30 in 432 aa NP_739246.1 Catalyzes hydrolysis of n-ribosyl-purine into a purine and d-ribose NP_739247.1 similar to AL646081-106|CAD18059.1| percent identity: 43 in 305 aa NP_739248.1 similar to Z99118-193|CAB14888.1| percent identity: 45 in 280 aa NP_739250.1 similar to AL589708-21|CAC33942.1| percent identity: 53 in 413 aa NP_739251.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP NP_739252.1 similar to AL589708-24|CAC33945.1| percent identity: 46 in 233 aa NP_739254.1 similar to AL589708-26|CAC33947.1| percent identity: 53 in 564 aa NP_739255.1 similar to AX063797-1|CAC25140.1| percent identity: 86 in 457 aa NP_739256.1 similar to AL022022-24|CAA17754.1| percent identity: 29 in 263 aa NP_739257.1 similar to AL591789-7|CAC46514.1| percent identity: 38 in 131 aa NP_739258.1 similar to AF417209-1|AAL09699.1| percent identity: 38 in 275 aa NP_739259.1 similar to AP001508-38|BAB04034.1| percent identity: 36 in 229 aa NP_739260.1 similar to AE008131-6|AAK87900.1| percent identity: 32 in 230 aa NP_739261.1 similar to AX067023-1|CAC26739.1| percent identity: 73 in 389 aa NP_739262.1 similar to AE007533-4|AAK78180.1| percent identity: 35 in 199 aa NP_739263.1 similar to AL356892-6|CAB92824.1| percent identity: 33 in 243 aa NP_739265.1 similar to AE002004-3|AAF11164.1| percent identity: 40 in 238 aa NP_739266.1 similar to AL391754-11|CAC05883.1| percent identity: 45 in 322 aa NP_739267.1 similar to AL646080-24|CAD17817.1| percent identity: 43 in 186 aa NP_739268.1 similar to AX064507-1|CAC25493.1| percent identity: 75 in 386 aa NP_739270.1 similar to AX065627-1|CAC26053.1| percent identity: 66 in 205 aa NP_739271.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_739272.1 similar to AE000669-16|AAC06391.1| percent identity: 41 in 437 aa NP_739273.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_739274.1 similar to AJ001436-1|CAA04760.1| percent identity: 47 in 582 aa NP_739277.1 similar to AE002005-10|AAF11179.1| percent identity: 24 in 450 aa NP_739280.1 similar to AL021929-1|CAA17329.1| percent identity: 42 in 383 aa NP_739283.1 similar to AL022486-7|CAA18562.1| percent identity: 37 in 674 aa NP_739284.1 similar to AE008910-1|AAL23292.1| percent identity: 43 in 160 aa NP_739285.1 similar to AL109848-25|CAB52849.1| percent identity: 39 in 253 aa NP_739286.1 similar to AL359215-17|CAB94641.1| percent identity: 23 in 320 aa NP_739287.1 similar to AL133220-19|CAB61719.1| percent identity: 37 in 359 aa NP_739288.1 similar to Z80225-12|CAB02348.1| percent identity: 33 in 106 aa NP_739290.1 similar to AX066533-1|CAC26494.1| percent identity: 75 in 343 aa NP_739292.1 similar to AL583926-32|CAC32114.1| percent identity: 32 in 442 aa NP_739293.1 similar to AL022486-2|CAA18552.1| percent identity: 51 in 365 aa NP_739294.1 similar to AJ248287-268|CAB50412.1| percent identity: 22 in 361 aa NP_739296.1 similar to AP001515-31|BAB06016.1| percent identity: 29 in 155 aa NP_739298.1 similar to AX065815-1|CAC26147.1| percent identity: 74 in 255 aa NP_739299.1 similar to AX066917-1|CAC26686.1| percent identity: 77 in 492 aa NP_739300.1 similar to AL133469-7|CAB63168.1| percent identity: 32 in 282 aa NP_739301.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP NP_739305.1 similar to AJ248285-162|CAB49718.1| percent identity: 22 in 336 aa NP_739306.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_739307.1 similar to Z95398-19|CAB08814.1| percent identity: 47 in 219 aa NP_739308.1 similar to AL583926-59|CAC32152.1| percent identity: 39 in 767 aa NP_739309.1 similar to AL021928-11|CAA17326.1| percent identity: 33 in 353 aa NP_739310.1 similar to AL583918-4|CAC29779.1| percent identity: 32 in 116 aa NP_739311.1 similar to AE000066-7|AAB91628.1| percent identity: 27 in 249 aa NP_739312.1 similar to AE009417-3|AAL45688.1| percent identity: 29 in 419 aa NP_739314.1 similar to AX066637-1|CAC26546.1| percent identity: 89 in 517 aa NP_739315.1 similar to AX066431-1|CAC26443.1| percent identity: 80 in 1652 aa NP_739316.1 Activates fatty acids by binding to coenzyme A NP_739317.1 similar to AE007184-7|AAK48275.1| percent identity: 39 in 297 aa NP_739319.1 similar to X66078-1|CAA46877.1| percent identity: 76 in 656 aa NP_739320.1 similar to X57229-1|CAA40506.1| percent identity: 35 in 321 aa NP_739321.1 similar to AE007185-3|AAK48278.1| percent identity: 41 in 576 aa NP_739322.1 catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate NP_739323.1 similar to AL360055-27|CAB96032.1| percent identity: 32 in 172 aa NP_739324.1 similar to AL022076-12|CAA17872.1| percent identity: 55 in 646 aa NP_739325.1 similar to AE004675-1|AAG05860.1| percent identity: 31 in 428 aa NP_739327.1 similar to AP003189-25|BAB80732.1| percent identity: 32 in 167 aa NP_739329.1 similar to AX065129-1|CAC25804.1| percent identity: 85 in 401 aa NP_739330.1 similar to AE007185-9|AAK48284.1| percent identity: 38 in 372 aa NP_739331.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_739332.1 similar to AL583917-60|CAC29597.1| percent identity: 44 in 277 aa NP_739333.1 similar to AX066521-1|CAC26488.1| percent identity: 67 in 281 aa NP_739334.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_739335.1 similar to AL359214-28|CAB94616.1| percent identity: 37 in 256 aa NP_739336.1 similar to AL583917-57|CAC29589.1| percent identity: 32 in 337 aa NP_739337.1 similar to AL118514-30|CAB56374.1| percent identity: 42 in 113 aa NP_739338.1 similar to AP003135-294|BAB43132.1| percent identity: 41 in 341 aa NP_739339.1 similar to AX066179-1|CAC26328.1| percent identity: 91 in 67 aa NP_739340.1 similar to AF030288-1|AAB84273.1| percent identity: 47 in 184 aa NP_739341.1 similar to AX065045-1|CAC25762.1| percent identity: 86 in 223 aa NP_739342.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis NP_739343.1 similar to AE007082-17|AAK46726.1| percent identity: 31 in 389 aa NP_739344.1 similar to AL583943-14|CAC32296.1| percent identity: 45 in 238 aa NP_739347.1 similar to AF107019-1|AAD28828.1| percent identity: 26 in 510 aa NP_739348.1 similar to AE006309-6|AAK04857.1| percent identity: 34 in 280 aa NP_739351.1 similar to AF106034-3|AAK30625.1| percent identity: 38 in 280 aa NP_739352.1 similar to AP001512-200|BAB05332.1| percent identity: 36 in 391 aa NP_739355.1 similar to AF263912-22|AAF71783.1| percent identity: 25 in 312 aa NP_739356.1 similar to AL596138-2|CAC44512.1| percent identity: 32 in 382 aa NP_739357.1 similar to U88088-3|AAD40345.1| percent identity: 54 in 97 aa NP_739358.1 similar to U32821-9|AAC23070.1| percent identity: 50 in 95 aa NP_739359.1 similar to AL596251-11|CAC44698.1| percent identity: 36 in 295 aa NP_739360.1 similar to AX066653-1|CAC26554.1| percent identity: 71 in 257 aa NP_739362.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_739363.1 Converts (S)-lactate and NAD(+) to pyruvate and NADH NP_739364.1 similar to AL021897-21|CAA17185.1| percent identity: 33 in 529 aa NP_739365.1 similar to X66249-1|CAA46976.1| percent identity: 26 in 208 aa NP_739366.1 similar to AF164961-9|AAF00220.1| percent identity: 33 in 186 aa NP_739367.1 similar to AE005947-2|AAK24777.1| percent identity: 30 in 219 aa NP_739368.1 similar to AB070940-3|BAB69187.1| percent identity: 48 in 255 aa NP_739369.1 similar to AF132735-7|AAF61311.1| percent identity: 21 in 275 aa NP_739370.1 similar to AE003473-26|AAG22226.1| percent identity: 24 in 176 aa NP_739371.1 similar to AL445963-23|CAC14378.1| percent identity: 38 in 459 aa NP_739372.1 similar to AX065009-1|CAC25744.1| percent identity: 92 in 415 aa NP_739374.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_739375.1 similar to AF236111-2|AAK01490.1| percent identity: 94 in 200 aa NP_739376.1 similar to AX066965-1|CAC26710.1| percent identity: 71 in 599 aa NP_739377.1 similar to AF235504-4|AAF86383.1| percent identity: 42 in 260 aa NP_739379.1 similar to AE004916-4|AAG08415.1| percent identity: 39 in 409 aa NP_739383.1 similar to AE007188-17|AAK48332.1| percent identity: 38 in 208 aa NP_739384.1 similar to AJ278289-1|CAC28154.1| percent identity: 33 in 235 aa NP_739385.1 similar to AP000981-85|BAB65026.1| percent identity: 41 in 284 aa NP_739386.1 similar to AE007970-8|AAK86138.1| percent identity: 42 in 261 aa NP_739387.1 similar to AE008758-20|AAL20275.1| percent identity: 34 in 556 aa NP_739388.1 similar to U75363-5|AAC23922.1| percent identity: 53 in 248 aa NP_739389.1 similar to AE001025-6|AAB90105.1| percent identity: 34 in 373 aa NP_739390.1 similar to Z99119-153|CAB15058.1| percent identity: 58 in 256 aa NP_739391.1 similar to AP001517-80|BAB06677.1| percent identity: 24 in 197 aa NP_739392.1 similar to AE001951-3|AAF10563.1| percent identity: 43 in 218 aa NP_739393.1 similar to AL583943-11|CAC32293.1| percent identity: 35 in 394 aa NP_739396.1 similar to AL079308-20|CAB45217.1| percent identity: 30 in 281 aa NP_739397.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_739398.1 similar to AL021646-18|CAA16638.1| percent identity: 33 in 200 aa NP_739400.1 similar to AE002069-10|AAF11934.1| percent identity: 43 in 83 aa NP_739401.1 similar to AX244027-1|CAC88492.1| percent identity: 90 in 295 aa NP_739402.1 similar to AE005869-1|AAK23932.1| percent identity: 41 in 316 aa NP_739403.1 similar to AX064301-1|CAC25391.1| percent identity: 75 in 339 aa NP_739409.1 similar to AX065341-1|CAC25910.1| percent identity: 76 in 190 aa NP_739411.1 similar to Z93777-9|CAB07822.1| percent identity: 58 in 265 aa NP_739412.1 similar to AF024666-23|AAG03374.1| percent identity: 72 in 51 aa NP_739413.1 similar to AF143862-6|AAF04480.1| percent identity: 34 in 55 aa NP_739419.1 similar to AB024564-5|BAA83965.1| percent identity: 27 in 118 aa NP_739420.1 similar to AL096884-31|CAB51454.1| percent identity: 26 in 407 aa NP_739421.1 similar to AC005893-12|AAF31041.1| percent identity: 25 in 271 aa NP_739422.1 similar to AL133422-17|CAB62676.1| percent identity: 52 in 122 aa NP_739423.1 similar to AX065969-1|CAC26224.1| percent identity: 66 in 65 aa NP_739424.1 similar to AE007908-8|AAK90769.1| percent identity: 31 in 447 aa NP_739425.1 similar to U28379-16|AAA89150.1| percent identity: 35 in 171 aa NP_739426.1 unwinds double stranded DNA NP_739428.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_739429.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_739430.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_739433.1 similar to AF187306-1|AAF25828.1| percent identity: 41 in 507 aa NP_739434.1 similar to AF165523-1|AAG13121.1| percent identity: 53 in 702 aa NP_739435.1 similar to AL583926-97|CAC32221.1| percent identity: 36 in 112 aa NP_739436.1 similar to Z80775-3|CAB02521.1| percent identity: 34 in 144 aa NP_739437.1 similar to AE007079-10|AAK46675.1| percent identity: 28 in 292 aa NP_739439.1 similar to AL583923-158|CAC30877.1| percent identity: 51 in 108 aa NP_739440.1 similar to AX244029-1|CAC88493.1| percent identity: 86 in 311 aa NP_739441.1 similar to AL603642-239|CAC48639.1| percent identity: 63 in 362 aa NP_739442.1 similar to AE007346-2|AAK74515.1| percent identity: 52 in 493 aa NP_739443.1 similar to AY065628-1|AAL40885.1| percent identity: 58 in 164 aa NP_739444.1 similar to AL442143-11|CAC10002.1| percent identity: 49 in 297 aa NP_739445.1 similar to AE006716-6|AAK41240.1| percent identity: 29 in 380 aa NP_739446.1 similar to AL627278-69|CAD07784.1| percent identity: 29 in 251 aa NP_739447.1 similar to U32723-11|AAC22061.1| percent identity: 37 in 161 aa NP_739448.1 similar to AX065577-1|CAC26028.1| percent identity: 75 in 327 aa NP_739449.1 similar to AL391763-23|CAC05958.1| percent identity: 59 in 394 aa NP_739450.1 similar to AX065193-1|CAC25836.1| percent identity: 67 in 493 aa NP_739451.1 similar to AL445945-18|CAC14351.1| percent identity: 31 in 155 aa NP_739455.1 similar to AE009266-7|AAL44177.1| percent identity: 29 in 404 aa NP_739457.1 similar to AX065981-1|CAC26230.1| percent identity: 79 in 198 aa NP_739458.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_739459.1 similar to AE004481-2|AAG03826.1| percent identity: 42 in 416 aa NP_739460.1 similar to AL596174-52|CAC98176.1| percent identity: 40 in 464 aa NP_739461.1 similar to L31763-11|AAB00945.1| percent identity: 51 in 96 aa NP_739462.1 similar to AF060489-3|AAC38618.1| percent identity: 36 in 83 aa NP_739468.1 in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol NP_739469.1 similar to AX066081-1|CAC26280.1| percent identity: 87 in 279 aa NP_739470.1 similar to AE005446-4|AAG57276.1| percent identity: 33 in 347 aa NP_739471.1 similar to AB054975-3|BAB55883.1| percent identity: 33 in 232 aa NP_739472.1 similar to AF279141-5|AAK58907.1| percent identity: 34 in 397 aa NP_739473.1 similar to AP003013-183|BAB53776.1| percent identity: 28 in 406 aa NP_739474.1 similar to AP003189-166|BAB80873.1| percent identity: 45 in 394 aa NP_739475.1 similar to AK006145-1|BAB24430.1| percent identity: 27 in 152 aa NP_739478.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_739479.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity NP_739480.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_739481.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate NP_739482.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_739483.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_739484.1 similar to AF263011-5|AAF81232.1| percent identity: 45 in 289 aa NP_739485.1 similar to AE007002-4|AAK45512.1| percent identity: 23 in 531 aa NP_739486.1 similar to AL109848-3|CAB52827.1| percent identity: 36 in 120 aa NP_739487.1 similar to AL596162-15|CAC44594.1| percent identity: 45 in 361 aa NP_739489.1 similar to AX065607-1|CAC26043.1| percent identity: 84 in 324 aa NP_739490.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_739491.1 similar to Z92539-28|CAB06871.1| percent identity: 32 in 114 aa NP_739495.1 similar to AE001901-7|AAF09991.1| percent identity: 33 in 315 aa NP_739496.1 ATP-dependent carboxylate-amine ligase NP_739497.1 similar to Z99109-115|CAB12879.1| percent identity: 34 in 499 aa NP_739501.1 similar to AL646080-25|CAD17818.1| percent identity: 22 in 396 aa NP_739502.1 similar to AF130250-3|AAD55886.1| percent identity: 40 in 357 aa NP_739503.1 similar to AE004989-10|AAG18860.1| percent identity: 28 in 274 aa NP_739504.1 similar to AE005661-4|AAG59488.1| percent identity: 32 in 758 aa NP_739505.1 similar to AE005661-3|AAG59487.1| percent identity: 27 in 2062 aa NP_739507.1 similar to AP002569-36|BAB38685.1| percent identity: 32 in 444 aa NP_739508.1 similar to AP002569-36|BAB38685.1| percent identity: 31 in 1311 aa NP_739511.1 similar to AE005149-5|AAG20812.1| percent identity: 22 in 861 aa NP_739512.1 similar to AE007049-14|AAK46203.1| percent identity: 35 in 255 aa NP_739513.1 similar to AE006303-6|AAK04800.1| percent identity: 36 in 480 aa NP_739514.1 similar to AP001520-62|BAB07557.1| percent identity: 36 in 213 aa NP_739515.1 similar to AL022374-19|CAA18527.1| percent identity: 34 in 546 aa NP_739516.1 similar to AE003885-2|AAF83131.1| percent identity: 47 in 477 aa NP_739518.1 similar to Y09102-3|CAA70320.1| percent identity: 48 in 140 aa NP_739519.1 similar to AE007667-1|AAK79536.1| percent identity: 44 in 143 aa NP_739520.1 similar to AL353872-18|CAB89069.1| percent identity: 34 in 99 aa NP_739521.1 similar to Z99122-1|CAB15521.1| percent identity: 32 in 1150 aa NP_739523.1 similar to X69104-2|CAA48850.1| percent identity: 88 in 298 aa NP_739524.1 similar to X69104-1|CAA48849.1| percent identity: 89 in 97 aa NP_739526.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine NP_739527.1 similar to AY034637-1|AAK61477.1| percent identity: 22 in 199 aa NP_739535.1 similar to AE004410-2|AAF96716.1| percent identity: 26 in 110 aa NP_739536.1 similar to AE000634-11|AAD08372.1| percent identity: 28 in 220 aa NP_739537.1 similar to AX064849-1|CAC25664.1| percent identity: 84 in 201 aa NP_739538.1 similar to AL583926-101|CAC32229.1| percent identity: 64 in 470 aa NP_739539.1 similar to AE007193-8|AAK48392.1| percent identity: 46 in 231 aa NP_739540.1 similar to AX005501-1|CAC05104.1| percent identity: 27 in 828 aa NP_739541.1 similar to AX064311-1|CAC25396.1| percent identity: 72 in 1005 aa NP_739542.1 similar to AL583920-154|CAC31457.1| percent identity: 29 in 196 aa NP_739543.1 similar to AF023161-1|AAB80939.1| percent identity: 68 in 312 aa NP_739544.1 similar to M14736-1|AAA22049.1| percent identity: 51 in 107 aa NP_739545.1 similar to AL583926-106|CAC32236.1| percent identity: 50 in 400 aa NP_739547.1 similar to AE007300-5|AAK65806.1| percent identity: 47 in 93 aa NP_739548.1 similar to AF024666-31|AAG03382.1| percent identity: 83 in 408 aa NP_739550.1 similar to AL583926-107|CAC32237.1| percent identity: 32 in 222 aa NP_739551.1 similar to AL583926-108|CAC32238.1| percent identity: 49 in 374 aa NP_739552.1 similar to AE007194-7|AAK48403.1| percent identity: 61 in 293 aa NP_739553.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_739554.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_739555.1 similar to AE008879-5|AAL22700.1| percent identity: 43 in 81 aa NP_739556.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_739557.1 in Escherichia coli transcription of this gene is enhanced by polyamines