-- dump date 20120504_143047 -- class Genbank::CDS -- table cds_note -- id note YP_001798599.1 contains a HNH endonuclease domain YP_001798600.1 contains a cobyrinic acid a,c-diamide synthase domain YP_001798601.1 contains a ribbon-helix-helix domain YP_001798602.1 contains CBS and CP12 domains YP_001798607.1 contains a plasmid pRiA4b ORF-3-like domain YP_001798615.1 contains a FtsK/SpoIIIE domain YP_001798633.1 contains DUF433 YP_001798658.1 contains a ribbon-helix-helix domain YP_001798664.1 contains an addiction module antidote domain YP_001798669.1 contains a HNH endonuclease domain YP_001798674.1 contains an alpha/beta hydrolase fold-1 domain YP_001798680.1 contains a Na-Ca exchanger/integrin-beta4 domain YP_001798684.1 contains MobA/MobL protein domains YP_001798701.1 contains a winged helix repressor DNA-binding domain YP_001798705.1 contains a bacterial mobilisation domain YP_001798708.1 contains an excinuclease ABC, C subunit, N-terminal domain YP_001801424.1 contains a glycoside hydrolase, family 24 domain YP_001801433.1 contains a Lambda repressor-like, DNA-binding domain YP_001801435.1 contains a peptidase M50 domain YP_001801436.1 contains a beta-lactamase-like domain YP_001801439.1 contains HesB/YadR/YfhF domains YP_001801440.1 contains a TPR-like helical domain YP_001801443.1 contains DUF820 YP_001801445.1 contains a RelA/SpoT domain YP_001801446.1 contains DUF820 YP_001801448.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001801452.1 contains a Ferritin/ribonucleotide reductase-like domain YP_001801467.1 contains DUF172 YP_001801471.1 contains a senescence marker protein-30 (SMP-30) domain YP_001801472.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001801474.1 contains an S-layer homology (SLH) domain YP_001801478.1 contains DUF318, transmembrane YP_001801482.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001801489.1 contains a GTP-binding protein, HSR1-related domain YP_001801499.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001801501.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001801504.1 contains an alpha/beta hydrolase fold-1 domain YP_001801511.1 contains a toll-Interleukin receptor domain YP_001801515.1 MobA; links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide; involved in molybdenum cofactor biosynthesis YP_001801521.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001801523.1 contains a transposase, IS4 domain YP_001801527.1 contains a polysaccharide deacetylase domain YP_001801528.1 contains a transposase, IS605 OrfB domain YP_001801529.1 contains DUF820 YP_001801537.1 contains UPF0150 YP_001801539.1 contains DUF306, Meta and HslJ YP_001801541.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001801548.1 contains an abortive infection protein domain YP_001801554.1 required for 70S ribosome assembly YP_001801556.1 contains an alpha/beta hydrolase fold-1 domain YP_001801557.1 contains a phospholipid/glycerol acyltransferase domain YP_001801558.1 contains DUF820 YP_001801559.1 contains a methyltransferase type 11 domain YP_001801575.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism YP_001801576.1 contains DUF427 YP_001801577.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001801578.1 contains a MOSC domain YP_001801585.1 contains a CHP147 domain YP_001801587.1 contains DUF540 YP_001801590.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001801604.1 contains DUF1704 YP_001801611.1 contains DUF1400 YP_001801613.1 contains DUF1400 YP_001801617.1 contains UPF0118 YP_001801625.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001801626.1 contains a Mechanosensitive ion channel, MscS domain YP_001801627.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001801632.1 contains DUF29 YP_001801634.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001801636.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001801638.1 contains a Rhodanese-like domain YP_001801640.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001801641.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001801642.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001801643.1 binds directly to 23S ribosomal RNA YP_001801644.1 Modulates Rho-dependent transcription termination YP_001801648.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001801649.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001801651.1 contains a stage II sporulation E domain YP_001801653.1 contains DUF6, transmembrane YP_001801655.1 contains a putative thiol-disulphide oxidoreductase DCC domain YP_001801656.1 contains a Na-Ca exchanger/integrin-beta4 domain YP_001801657.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001801658.1 phytyltransferase acting specifically in the tocopherol biosynthetic pathway; member of the UbiA prenyltransferase family which catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001801661.1 contains DUF187 YP_001801663.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001801664.1 contains a Mechanosensitive ion channel, MscS domain YP_001801675.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001801677.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001801680.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001801691.1 contains a N-acylglucosamine 2-epimerase-type domain and a ThiJ/PfpI domain YP_001801698.1 contains DUF785 YP_001801699.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001801704.1 involved in light-induced Na+-dependent proton extrusion YP_001801707.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001801708.1 contains a heat shock protein DnaJ, N-terminal domain YP_001801710.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001801716.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001801718.1 contains glutathione S-transferase, C-terminal-like and Thioredoxin fold domains YP_001801726.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001801731.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001801732.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine YP_001801734.1 contains an ABC-1 domain YP_001801737.1 Converts chlorophyllide a into protochlorophyllide; light dependent YP_001801739.1 contains a filamentous haemagglutinin, N-terminal domain YP_001801740.1 contains a bacterial surface antigen (D15) and Polypeptide-transport-associated, ShlB-type domain YP_001801741.1 contains DUF58 YP_001801744.1 catalyzes branch migration in Holliday junction intermediates YP_001801748.1 contains DUF124 YP_001801749.1 contains DUF124 YP_001801757.1 contains DUF187 YP_001801760.1 contains DUF172 YP_001801768.1 contains a CRISPR-associated protein Crm2 domain YP_001801769.1 contains DUF820 YP_001801774.1 contains DUF324 YP_001801781.1 contains a glutathione-dependent formaldehyde-activating, GFA domain YP_001801784.1 contains an ABC-1 domain YP_001801786.1 contains a pyridoxamine 5'-phosphate oxidase-related, FMN-binding domain YP_001801789.1 contains EAL, Chase2 and GGDEF domains YP_001801794.1 contains a methyltransferase FkbM domain YP_001801797.1 contains DUF29 YP_001801798.1 contains DUF29 YP_001801799.1 contains a thymidylate synthase domain YP_001801806.1 contains a TrkA-N domain YP_001801808.1 contains a Ribonucleotide reductase regulator NrdR-like domain YP_001801809.1 Ycf8; may be involved in the formation and/or stabilization of PSII system complexes YP_001801814.1 contains a HTTM domain YP_001801817.1 photosystem I subunit PsaK; maybe involved in the assembly of PSI monomers into trimers; active under low light conditions YP_001801818.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001801820.1 contains a MscS mechanosensitive ion channel domain YP_001801821.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001801824.1 contains Mur ligase and DUF1727 domains YP_001801825.1 contains a HNH endonuclease domain YP_001801828.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_001801830.1 contains a secretion protein HlyD domain YP_001801832.1 contains FbpA fibronectin-binding and DUF814 domains YP_001801839.1 acts as a promotor non-specific transcription repressor YP_001801840.1 Decreases the phosphorylation of KaiC, a component of the main circadian regulator in cyanobacteria YP_001801843.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001801855.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001801856.1 contains DUF323 and a CopG-like DNA-binding domain YP_001801858.1 Psb29; involved in biogenesis of the photosystem II; in Arabidopsis it interacts with the heterotrimeric G-protein (GPA1) and seems to be involved in a D-glucose signaling mechanism between plastid and the plasma membranes YP_001801868.1 contains a glutathione-dependent formaldehyde-activating, GFA domain YP_001801869.1 contains a transcriptional regulator, Rrf2 domain YP_001801872.1 contains a DnaJ N-terminal four helical 'J' domain YP_001801877.1 NADH-dependent; catalyzes a key regulatory step in fatty acid biosynthesis YP_001801881.1 contains a Sulfotransferase domain YP_001801885.1 contains a MFS 1 domain YP_001801887.1 contains an Anti-sigma factor antagonist domain YP_001801888.1 contains UPF0004 YP_001801894.1 contains a Thioredoxin fold domain YP_001801897.1 contains a rare lipoprotein A domain YP_001801898.1 contains TPR_1 tetratricopeptide repeat domains YP_001801900.1 contains a Glyoxalase/extradiol ring-cleavage dioxygenase domain YP_001801902.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001801904.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001801905.1 contains a GUN4-like domain YP_001801906.1 contains a MscS mechanosensitive ion channel and a cyclic nucleotide-binding domain YP_001801907.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001801909.1 contains rfrA pentapeptide repeat and TPR_1 tetratricopeptide repeat domains YP_001801919.1 fusion of two genes involved in the fifth and sixth steps of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate and converts orotidine 5'phosphate to UMP and carbon dioxide YP_001801920.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001801925.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001801926.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001801927.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001801930.1 contains a macrocin-O-methyltransferase domain YP_001801934.1 contains a glycosyl transferase, family 2 domain YP_001801936.1 contains glycosyl transferase, family 2 and Methyltransferase type 12 domains YP_001801938.1 contains a methyltransferase FkbM domain YP_001801939.1 contains a methyltransferase FkbM domain YP_001801941.1 contains a glycosyl transferase, group 1 domain YP_001801942.1 contains a glycosyl transferase, family 2 domain YP_001801943.1 contains a methyltransferase FkbM domain YP_001801949.1 contains a thioredoxin fold domain YP_001801955.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001801956.1 contains EAL and PAS fold-3 domains YP_001801963.1 contains a thioredoxin fold domain YP_001801966.1 in Methanococcus jannaschii this protein catalyzes the condensation of alpha-ketoglutarate and acetyl-CoA to form trans-homoaconitate; functions in alphaketosuberate synthesis which is a precursor in coenzyme B and biotin synthesis YP_001801979.1 contains a Mo-dependent nitrogenase, C-terminal domain YP_001801981.1 functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001801985.1 associates with NifD and may protect the nitrogenase Fe-Mo protein from oxidative damage YP_001801994.1 contains DUF81 YP_001802000.1 contains a PilT protein, N-terminal domain YP_001802002.1 contains DUF433 YP_001802004.1 contains a phosphoribosyltransferase domain YP_001802005.1 contains TPR_1 tetratricopeptide repeat domains YP_001802007.1 participates in electron transfer in photosystem I YP_001802008.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001802011.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001802012.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001802014.1 contains DUF1400 YP_001802015.1 contains an S-layer homology (SLH) domain YP_001802020.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001802021.1 catalyzes the transfer of electrons from NADH to ubiquinone; NdhD3 is associated with a low CO2-induced uptake system YP_001802023.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001802033.1 contains a methyltransferase type 12 domain YP_001802035.1 contains DUF820 YP_001802037.1 contains DUF29 YP_001802042.1 contains DUF820 YP_001802044.1 contains a TPR-like helical domain YP_001802045.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001802048.1 contains DUF820 YP_001802049.1 contains a methyltransferase type 11 domain YP_001802059.1 contains DUF21 and CBS domains YP_001802061.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; the sigma factors in this cluster are not required for growth or development, however may be involved in expression of nitrogen fixation genes YP_001802075.1 contains an Armadillo-like helical domain YP_001802079.1 contains a CHAD domain YP_001802080.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001802083.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001802086.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001802093.1 contains UPF0118 YP_001802102.1 with SufCD activates cysteine desulfurase SufS YP_001802105.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001802109.1 contains a GCN5-related N-acetyltransferase domain YP_001802111.1 contains a methyltransferase type 11 domain YP_001802118.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001802122.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001802124.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001802125.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001802131.1 contains a CheW-like domain YP_001802138.1 contains a Phage integrase-like, catalytic core domain YP_001802144.1 contains a winged helix repressor DNA-binding domain YP_001802146.1 contains DUF124 YP_001802147.1 contains DUF124 YP_001802148.1 contains DUF124 YP_001802149.1 contains a Peptidase M48, Ste24p domain YP_001802151.1 contains a quinoprotein amine dehydrogenase, beta chain-like domain YP_001802152.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001802154.1 contains a Ycf66, N-terminal domain YP_001802166.1 contains a peptidase M48, Ste24p domain YP_001802168.1 contains a glycosyl transferase, family 2 domain YP_001802175.1 negatively supercoils closed circular double-stranded DNA YP_001802179.1 contains a mechanosensitive ion channel, MscS domain YP_001802181.1 contains TPR_1 tetratricopeptide repeat domains YP_001802184.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001802185.1 contains GGDEF, EAL and Histidine kinase HAMP region domains YP_001802188.1 contains a ferredoxin domain YP_001802189.1 contains a FAD dependent oxidoreductase domain YP_001802191.1 contains DUF21 and CBS domains YP_001802192.1 contains a FAD dependent oxidoreductase domain YP_001802195.1 contains a Ferritin/ribonucleotide reductase-like domain YP_001802198.1 contains a bacterial regulatory factor, effector domain YP_001802200.1 contains a mechanosensitive ion channel domain YP_001802201.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001802202.1 contains DUF820 YP_001802205.1 contains a peptidase S8 and S53 domain YP_001802206.1 contains a phosphoesterase cyanobacterial, all2852 domain YP_001802207.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001802209.1 contains DUF411 and Thioredoxin fold domains YP_001802210.1 contains a cupredoxin domain YP_001802212.1 contains a peptidase M48, Ste24p domain YP_001802215.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001802217.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001802218.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001802220.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001802222.1 catalyzes the phosphorylation of NAD to NADP YP_001802223.1 contains a rieske [2Fe-2S] region domain YP_001802228.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001802235.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001802239.1 contains a DRTGG domain YP_001802246.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001802248.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001802250.1 contains a methyltransferase type 12 domain YP_001802252.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001802267.1 contains an amidohydrolase 2 domain YP_001802269.1 contains DUF6, transmembrane YP_001802270.1 contains a phosphoribosyltransferase domain YP_001802277.1 may be involved in regulating PSII assembly and/or stability YP_001802278.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001802281.1 contains DUF820 YP_001802283.1 contains a PilT protein, N-terminal domain YP_001802285.1 contains DUF820 YP_001802287.1 contains a secretion protein HlyD domain YP_001802292.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001802293.1 contains an acid phosphatase/vanadium-dependent haloperoxidase domain YP_001802297.1 contains a transposase, IS605 OrfB domain YP_001802298.1 contains DUF29 YP_001802308.1 contains an outer membrane efflux protein domain YP_001802312.1 contains helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains YP_001802314.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001802318.1 contains DUF1622 YP_001802319.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001802321.1 contains a Homeodomain-like domain YP_001802325.1 contains a Lambda repressor-like, DNA-binding domain YP_001802326.1 contains DUF955 YP_001802329.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001802334.1 contains DUF820 YP_001802338.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001802341.1 contains a glycosyl transferase, family 9 domain YP_001802344.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001802345.1 contains a GCN5-related N-acetyltransferase domain YP_001802352.1 contains a peptidase U62, modulator of DNA gyrase domain YP_001802357.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001802364.1 contains DUF820 YP_001802366.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001802372.1 contains a phage Gp37Gp68 domain YP_001802379.1 contains a glycosyl transferase, family 2 domain YP_001802380.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001802384.1 contains a recombinase domain YP_001802401.1 contains DUF172 YP_001802402.1 contains DUF820 YP_001802403.1 contains a methyltransferase type 11 domain YP_001802404.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001802406.1 with PsaB binds the primary electron donor of photosystem I, P700, and subsequent electron acceptors as part of photosystem I YP_001802407.1 with PsaA binds the primary electron donor of photosystem I, P700, and subsequent electron acceptors as part of photosystem I YP_001802412.1 Catalyzes a reaction in which the CO2 acceptor molecule, RuBP, is generated via the phosphorylation of ribulose 5-phosphate with ATP YP_001802415.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001802417.1 contains a SMAD/FHA domain YP_001802423.1 contains a FAD linked oxidase, N-terminal domain YP_001802424.1 contains an allergen V5/Tpx-1 related domain YP_001802425.1 contains a radical SAM domain YP_001802435.1 catalyzes the formation of (2R)-3-sulfolactate from (2R)-2-phospho-3-sulfolactate YP_001802440.1 contains an Acyl carrier protein-like domain YP_001802446.1 catalyzes the formation of N-succinyl-2-L-amino-6-oxoheptanedioate and L-glutamate from N-succinyl-L-2,6-diaminoheptanedioate and 2-oxoglutarate YP_001802449.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001802451.1 contains a Ferritin/ribonucleotide reductase-like domain YP_001802458.1 contains DUF323 YP_001802465.1 contains a Mo-dependent nitrogenase, C-terminal domain YP_001802468.1 contains DUF820 YP_001802491.1 contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 domain YP_001802492.1 contains a GUN4-like domain and a Peptidase, trypsin-like serine and cysteine domain YP_001802494.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; note this protein has an additional C-terminal tail of unknown function as compared to similar bifunctional enzymes YP_001802495.1 contains UPF0150 YP_001802496.1 contains a metallophosphoesterase domain YP_001802497.1 contains a TPR-like helical domain YP_001802498.1 contains DUF820 YP_001802501.1 contains DUF102 YP_001802504.1 contains DUF132 YP_001802509.1 contains a TROVE domain YP_001802510.1 contains DUF29 YP_001802524.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001802525.1 contains DUF820 YP_001802528.1 contains a Band 7 domain YP_001802534.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001802537.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001802540.1 contains a peptidase, trypsin-like serine and cysteine domain YP_001802541.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001802542.1 contains Lambda repressor-like, DNA-binding and DUF 955 domains YP_001802547.1 contains a WD-40 repeat and a protein kinase YP_001802552.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001802559.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001802561.1 contains DUF29 YP_001802562.1 contains DUF29 YP_001802563.1 contains DUF820 YP_001802567.1 contains a DNA polymerase, beta-like region YP_001802572.1 contains DUF490 YP_001802573.1 contains DUF6, transmembrane YP_001802574.1 contains tetratricopeptide repeat domains YP_001802585.1 contains a Lipolytic enzyme, G-D-S-L domain YP_001802586.1 contains a glycosyl transferase, family 2 domain YP_001802587.1 contains a TPR-like helical domain YP_001802588.1 contains a winged helix repressor DNA-binding and a Pleckstrin/ G-protein domain, interacting region domains YP_001802592.1 transfers electrons from NAD(P)H to quinons in the respiratory chain YP_001802595.1 contains an S-layer homology (SLH) domain YP_001802596.1 contains a cupredoxin domain YP_001802600.1 contains a SpoIID/LytB domain YP_001802604.1 contains a type I restriction enzyme R protein, N terminus domain YP_001802608.1 contains winged helix repressor DNA-binding and a helix-turn-helix, type 11 domains YP_001802610.1 contains a CRISPR-associated helicase Cas3, core domain YP_001802614.1 contains DUF48 and CRISPR-associated protein Cas4 domains YP_001802617.1 contains DUF29 YP_001802618.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_001802620.1 contains a UspA domain YP_001802622.1 contains PAS, GGDEF, and GAF domains YP_001802624.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001802626.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001802627.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001802632.1 contains DUF820 YP_001802634.1 contains UPF0150 YP_001802635.1 contains aYcfA domain YP_001802639.1 ferredoxin-dependent assimilatory nitrite reductase YP_001802640.1 contains DUF172 YP_001802641.1 contains a Peptidase aspartic, catalytic domain YP_001802651.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001802652.1 contains DUF820 YP_001802655.1 contains TPR_1 tetratricopeptide repeat domains YP_001802660.1 contains a GGDEF domain and EAL domain YP_001802663.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001802664.1 contains a Ion transport 2, bacterial domain YP_001802665.1 contains DUF1400 YP_001802668.1 contains DUF1214 and DUF1254 YP_001802682.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001802685.1 contains UPF0118 YP_001802689.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001802702.1 contains a UspA domain YP_001802703.1 contains an aldo/keto reductase domain YP_001802705.1 Enables the organization of the psaE and psaF subunits YP_001802708.1 contains CBS, DUF21, and transporter-associated region domains YP_001802713.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001802715.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001802717.1 contains TPR_1 tetratricopeptide repeat domains YP_001802719.1 may be involved in assembling and maintaining PSII complexes in the thylakoid membrane YP_001802720.1 may have a role in PSII core assembly, maintaining PSII dimers and donor side electron transfer YP_001802721.1 photosystem II reaction center subunit VI; associated with the reaction center of photosystem II YP_001802723.1 photosystem II reaction center subunit VI; associated with the reaction center of photosystem II YP_001802724.1 similar to Arabidopsis thaliana photosystem II assembly protein YP_001802728.1 contains DUF124 YP_001802732.1 contains an ankyrin domain YP_001802733.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_001802734.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001802737.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001802738.1 unknown function; YciI from Haemophilus influenzae has a crystal structure similar to a muconolactone isomerase, but does not seem to catalyze any of the reactions predicted from the sequence or structure similarity YP_001802747.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001802759.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001802760.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001802762.1 contains a transposase, IS605 OrfB domain YP_001802765.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001802766.1 contains DUF147 YP_001802769.1 contains a SNF2-related helicase YP_001802772.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001802773.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001802779.1 contains a single-stranded nucleic acid binding R3H domain YP_001802780.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001802782.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001802783.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001802787.1 contains UPF0118 YP_001802789.1 contains a polypeptide-transport-associated, FtsQ-type domain YP_001802792.1 catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate YP_001802799.1 electron transport protein YP_001802800.1 PetD, with cytochrome b6, cytochrome F, and the Rieske protein, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001802804.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001802805.1 contains a Rhodanese-like domain YP_001802808.1 involved in the peptidyltransferase reaction during translation YP_001802811.1 contains a glycosyl transferase, family 10 domain YP_001802814.1 contains GGDEF, EAL, and Histidine kinase HAMP region domains YP_001802816.1 contains Peptidase S8 and S53/subtilisin/kexin/sedolisin domains YP_001802817.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001802818.1 contains a glycosyl transferase, family 39 domain YP_001802820.1 contains DUF820 YP_001802821.1 contains DUF820 YP_001802823.1 contains a cupin, RmlC-type domain YP_001802826.1 contains a HTTM domain YP_001802827.1 contains GGDEF and GAF domains YP_001802835.1 contains DUF1400 YP_001802836.1 contains HesB/YadR/YfhF domains YP_001802841.1 contains DUF820 YP_001802845.1 contains a DnaJ N-terminal four helical 'J' domain YP_001802846.1 contains a short-chain dehydrogenase/reductase SDR domain YP_001802850.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001802851.1 contains an EAL signaling domain YP_001802853.1 contains a CHRD domain YP_001802854.1 contains polynucleotidyl transferase, Ribonuclease H fold and Transposase, IS4 domains YP_001802864.1 contains a TspO/MBR-related protein domain YP_001802871.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001802873.1 contains an alpha amylase catalytic subdomain YP_001802874.1 contains an alpha amylase catalytic subdomain YP_001802876.1 contains an ankyrin domain YP_001802888.1 contains a DnaJ N-terminal four helical 'J' domain YP_001802890.1 amylomaltase; acts to release glucose from maltodextrins YP_001802892.1 contains DUF6, transmembrane YP_001802896.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001802899.1 contains a MscS Mechanosensitive ion channel domain YP_001802903.1 contains a WD40-like domain YP_001802904.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001802905.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001802906.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001802907.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001802909.1 contains a phosphoesterase MJ0912 domain YP_001802911.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001802916.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001802917.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001802919.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001802920.1 contains aYcfA domain YP_001802921.1 contains UPF0150 YP_001802922.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001802924.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001802928.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001802929.1 contains an S-layer homology (SLH) domain YP_001802930.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001802937.1 contains PAS, GGDEF, EAL, Response regulator receiver, CheY-like, and PAS fold-3 domains YP_001802939.1 contains a glyoxalase/bleomycin resistance protein/dioxygenase domain YP_001802943.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001802952.1 contains an ABC-1 domain YP_001802954.1 contains a glycosyl transferase, family 39 domain YP_001802955.1 contains an acid phosphatase/vanadium-dependent haloperoxidase domain YP_001802958.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001802962.1 contains DUF6, transmembrane YP_001802971.1 contains a GAF domain YP_001802977.1 synthesizes RNA primers at the replication forks YP_001802982.1 contains DUF323 YP_001802986.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001802995.1 contains a fimbrial assembly domain YP_001803001.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001803002.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_001803005.1 contains a transglutaminase-like domain YP_001803007.1 contains DUF820 YP_001803008.1 contains a DNA polymerase, beta-like region domain YP_001803009.1 contains DUF86 YP_001803012.1 contains UPF0150 YP_001803015.1 PsbW; part of the phosystem II reaction center YP_001803025.1 contains DUF608 YP_001803030.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001803032.1 contains a glycosyl transferase, family 39 domain YP_001803033.1 contains DUF1400 YP_001803039.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001803040.1 contains DUF502 YP_001803043.1 contains a glycoside hydrolase, family 57 domain YP_001803049.1 contains a TolB, C-terminal domain YP_001803051.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001803055.1 contains an alpha amylase catalytic subdomain YP_001803061.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001803062.1 contains a peptidase, archaeal and bacterial C-terminal domain YP_001803065.1 contains a nuclear transport factor 2 domain YP_001803075.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001803077.1 contains DUF421 YP_001803082.1 contains a GTP-binding protein, HSR1-related domain YP_001803087.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001803090.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001803096.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001803101.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001803102.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001803106.1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunit D, with NdhB and NdhF are core membrane components YP_001803108.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001803109.1 catalyzes the transfer of electrons from NADH to ubiquinone; NdhD4 is possibly involved in a constitutive CO(2)-uptake system YP_001803117.1 contains a cupredoxin domain YP_001803119.1 contains a plasmid stabilization system domain YP_001803124.1 contains a secretion protein HlyD domain YP_001803125.1 contains an alpha/beta hydrolase fold-1 domain YP_001803126.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001803135.1 contains DUF187 YP_001803136.1 contains a Peptidase aspartic, catalytic domain YP_001803138.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001803142.1 contains DUF820 YP_001803157.1 contains DUF29 YP_001803158.1 contains DUF820 YP_001803163.1 part of the core of the reaction center of photosystem I YP_001803165.1 contains a conserved TM helix domain YP_001803167.1 interacts with the circadian clock regulator KaiC to maintain circadian rhythms YP_001803172.1 contains TPR_1 tetratricopeptide repeat domains YP_001803174.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001803178.1 catalyzes the transfer of electrons from NADH to quinones YP_001803179.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001803180.1 Catalyzes the transfer of electrons from NADH to quinone YP_001803181.1 contains a DNA methylase N-4/N-6 domain YP_001803188.1 catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate YP_001803197.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001803205.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001803208.1 contains an acid phosphatase/vanadium-dependent haloperoxidase domain YP_001803214.1 similar to YegS from E. coli YP_001803217.1 contains an Anti-sigma factor antagonist domain YP_001803218.1 Essential for efficient processing of 16S rRNA YP_001803219.1 contains a polysaccharide export protein domain YP_001803221.1 contains DUF888 YP_001803235.1 contains a MscS Mechanosensitive ion channel domain YP_001803238.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001803243.1 contains an O-antigen polymerase domain YP_001803244.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001803245.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001803246.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001803247.1 contains a CHP1784 domain YP_001803248.1 contains a Thioesterase superfamily domain YP_001803251.1 contains UPF0150 YP_001803252.1 contains a YcfA domain YP_001803255.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001803257.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001803258.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001803260.1 contains an EF-Hand type domain YP_001803280.1 binds the polymerase to DNA and acts as a sliding clamp YP_001803281.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001803283.1 contains a Phospholipid/glycerol acyltransferase domain YP_001803288.1 contains a Cytochrome c region domain YP_001803293.1 contains a PAS domain, GGDEF domain, EAL domain, Response regulator receiver domain, CheY-like domain, and a PAS fold domain YP_001803303.1 contains a Phage integrase-like, catalytic core domain YP_001803304.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_001803320.1 contains DUF564 YP_001803322.1 contains DUF86 YP_001803326.1 ClpR variant present in an operon with ClpP3 in Synechococcus PCC7942; ClpR is missing the catalytic triad Ser-His-Asp characteristic of serine-type proteases; the exact function of ClpR and ClpP3 is unknown however they appear to be necessary for cell viability; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001803327.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001803340.1 contains a GTP-binding protein, HSR1-related domain YP_001803341.1 contains a GTP-binding protein, HSR1-related domain YP_001803361.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001803362.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001803363.1 contains DUF88 YP_001803365.1 contains carbohydrate kinase and YjeF-related protein, N-terminal domains YP_001803370.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001803373.1 contains UPF0150 YP_001803374.1 contains a YcfA domain YP_001803375.1 contains a plasmid stabilization system domain YP_001803377.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001803386.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001803396.1 contains a Rhodanese-like domain YP_001803397.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_001803400.1 contains DUF820 YP_001803405.1 contains a short-chain dehydrogenases/reductase domain YP_001803419.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001803422.1 contains a DoxX domain YP_001803423.1 contains a secretion protein HlyD domain YP_001803425.1 contains a beta-lactamase-like domain YP_001803427.1 contains a Cupin, RmlC-type domain YP_001803432.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001803441.1 contains DUF820 YP_001803445.1 contains an OstA-like protein domain YP_001803448.1 contains PAS fold-3, GAF, ELA, and GGDEF domains YP_001803449.1 contains a Glycosyl transferase, family 39 domain YP_001803454.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001803457.1 contains DUF81 YP_001803458.1 contains DUF477 YP_001803460.1 contains an acid phosphatase/vanadium-dependent haloperoxidase domain YP_001803461.1 contains a TPR-like helical domain YP_001803462.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001803467.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001803474.1 contains a Chase2 domain YP_001803475.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001803492.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001803493.1 contains a Cupin, RmlC-type domain YP_001803498.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001803501.1 contains an FMN-binding split barrel-related domain YP_001803503.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001803504.1 contains a PilT, N-terminal domain YP_001803505.1 contains a serralysin-like metalloprotease, C-terminal and PKD domains YP_001803510.1 contains a Methyltransferase type 11 domain YP_001803515.1 contains a methyltransferase, FkbM domain YP_001803520.1 contains UPF0102 YP_001803521.1 contains tetratricopeptide repeat domains YP_001803523.1 contains a Phycobilisome protein and a globin-like domain YP_001803525.1 contains a 4-vinyl reductase, 4VR domain YP_001803526.1 contains a Phycobilisome protein and a globin-like domain YP_001803528.1 contains a 4-vinyl reductase, 4VR domain YP_001803530.1 contains DUF1622 YP_001803536.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001803538.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001803539.1 contains a Methyltransferase type 11 domain YP_001803540.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001803546.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001803549.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001803550.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001803552.1 contains DUF955 YP_001803554.1 contains a proto-chlorophyllide reductase 57 kD subunit YP_001803565.1 contains DUF820 YP_001803566.1 contains a transglutaminase-like domain YP_001803567.1 contains a Methyltransferase type 11 domain YP_001803568.1 This protein performs the mismatch recognition step during the DNA repair process YP_001803572.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001803583.1 contains a Peptidase M48, Ste24p domain YP_001803585.1 contains a TerC domain YP_001803586.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001803588.1 required for the assembly of photosystem I complex YP_001803591.1 contains Forkhead-associated, ferredoxin, and Oxidoreductase FAD/NAD(P)-binding domains YP_001803594.1 contains a YcfA domain YP_001803595.1 contains UPF0150 YP_001803611.1 contains a hemolysin-type calcium-binding region YP_001803617.1 contains a Methyltransferase type 11 domain YP_001803621.1 contains a cell envelope-related transcriptional attenuator domain YP_001803624.1 contains an FMN-binding split barrel-related domain YP_001803625.1 contains a peptidase M20 domain YP_001803627.1 contains a ThiJ/PfpI domain YP_001803632.1 contains a CHP730 domain YP_001803634.1 contains DUF457, transmembrane YP_001803635.1 contains a GCN5-related N-acetyltransferase domain YP_001803636.1 contains FAD dependent oxidoreductase and Phytoene dehydrogenase-related domains YP_001803637.1 Catalyzes the transfer of electrons from NADH to quinone YP_001803638.1 Catalyzes the transfer of electrons from NADH to quinone YP_001803639.1 Catalyzes the transfer of electrons from NADH to quinone YP_001803640.1 Catalyzes the transfer of electrons from NADH to quinone YP_001803651.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001803653.1 catalyze the formation of cyanophycin which may act to store excess nitrogen YP_001803654.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001803655.1 contains an abortive infection protein domain YP_001803657.1 contains a Filamentous haemagglutinin, N-terminal domain YP_001803658.1 contains a bacterial surface antigen (D15) domain YP_001803659.1 contains a GGDEF domain, EAL domain, and a pass fold-4 domain YP_001803663.1 contains a beta-lactamase-like domain YP_001803664.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001803665.1 contains TPR_1 tetratricopeptide repeat domains YP_001803668.1 contains an ABC-1 domain YP_001803671.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001803682.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001803683.1 contains a peptidase M50 domain YP_001803688.1 contains UPF0118 YP_001803689.1 contains DUF39 YP_001803693.1 contains an extracellular ligand-binding receptor domain YP_001803694.1 contains TPR_1 tetratricopeptide repeat domains YP_001803698.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001803703.1 contains an S-layer homology (SLH) domain YP_001803704.1 contains TPR_1 tetratricopeptide repeat domains YP_001803711.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001803714.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001803717.1 contains a HAD-superfamily hydrolase subfamily IIB domain YP_001803720.1 contains tetratricopeptide repeat domains YP_001803721.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001803723.1 contains a plasmid stabilization system domain YP_001803728.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001803730.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001803733.1 with HoxF and HoxE catalyzes H2-dependent NAD(P)+-reduction as well as NAD(P)H-dependent H2-evolution YP_001803736.1 contains DUF820 YP_001803737.1 contains DUF820 YP_001803739.1 contains a catalase domain YP_001803749.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001803758.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001803761.1 contains a Cupin, RmlC-type domain YP_001803763.1 contains a PHP, C-terminal domain YP_001803765.1 contains a single-stranded nucleic acid binding R3H and AAA ATPase domain YP_001803775.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001803776.1 contains a Peptidase M23B and Peptidoglycan-binding domain YP_001803788.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001803789.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001803793.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001803795.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001803800.1 contains a mechanosensitive ion channel, MscS domain YP_001803808.1 contains a YcfA domain YP_001803809.1 contains UPF0150 YP_001803816.1 contains glutaredoxin 2 and thioredoxin fold domains YP_001803818.1 contains an oxidoreductase, molybdopterin binding domain YP_001803819.1 contains glycosyl transferase, family 2 and Methyltransferase FkbM domains YP_001803821.1 contains DUF1400 YP_001803826.1 contains a UspA domain YP_001803832.1 contains a DNA polymerase, beta-like region domain YP_001803833.1 contains a penicillin-binding protein, transpeptidase fold domain YP_001803838.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001803840.1 contains ErfK/YbiS/YcfS/YnhG domains YP_001803841.1 contains a Mo-dependent nitrogenase, C-terminal domain YP_001803845.1 contains DUF389 YP_001803849.1 contains DUF323 YP_001803851.1 contains a HAD-superfamily hydrolase subfamily IIB domain YP_001803853.1 contains a TrkA-N domain YP_001803860.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001803863.1 contains a glycoside hydrolase, family 57 domain YP_001803870.1 contains a Glycosyl transferase, family 39 domain YP_001803871.1 contains an abortive infection protein domain YP_001803875.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001803880.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001803883.1 contains DUF820 YP_001803886.1 contains a beta-Ig-H3/fasciclin domain YP_001803887.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001803890.1 blocks the formation of polar Z-ring septums YP_001803892.1 contains a FAD dependent oxidoreductase domain YP_001803893.1 contains a NADPH-dependent FMN reductase domain YP_001803894.1 contains an alpha/beta hydrolase fold YP_001803906.1 contains an ankyrin domain YP_001803907.1 contains a DNA repair protein RadC fragment YP_001803908.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001803909.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001803911.1 contains a phage integrase-like, catalytic core domain YP_001803912.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001803914.1 contains a radical SAM domain YP_001803926.1 contains an aldo/keto reductase domain YP_001803934.1 contains DUF565 YP_001803938.1 contains a methyltransferase type 11 domain YP_001803943.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001803947.1 contains a phosphoglycerate mutase domain YP_001803950.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001803952.1 contains a peptidase M48, Ste24p domain YP_001803956.1 contains a serralysin-like metalloprotease, C-terminal domain YP_001803959.1 contains a Ion transport 2, bacterial domain YP_001803966.1 contains amidinotransferase and CHP300 domains YP_001803978.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001803979.1 contains DUF364 YP_001803980.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls the expression of genes coding cell surface proteins involved in motility and growth on nitrogen YP_001803981.1 contains an Armadillo-like helical domain YP_001803982.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001803984.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001803990.1 contains DUF820 YP_001803991.1 contains an alpha/beta hydrolase fold-1 domain YP_001803992.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001803997.1 contains DUF29 YP_001803998.1 contains a restriction endonuclease domain YP_001804007.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001804009.1 contains DSBA oxidoreductase and Thioredoxin fold domains YP_001804010.1 contains a Lipolytic enzyme, G-D-S-L domain YP_001804012.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001804014.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001804019.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis YP_001804023.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001804025.1 contains PAS, GGDEF, Response regulator receiver, and GAF domains YP_001804027.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001804028.1 contains DUF552 YP_001804029.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001804031.1 contains DUF900, hydrolase-like YP_001804036.1 contains TPR_1 tetratricopeptide repeat domains YP_001804037.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001804041.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001804042.1 contains DUF820 YP_001804043.1 contains TPR_1 tetratricopeptide repeat domains YP_001804044.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001804048.1 contains an FeoA domain YP_001804049.1 contains a cupredoxin domain YP_001804053.1 contains a Rhodanese-like domain YP_001804057.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001804061.1 contains a succinylglutamate desuccinylase/aspartoacylase domain YP_001804063.1 contains a cytochrome P450 domain YP_001804072.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001804073.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001804075.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001804077.1 contains a peptidase M23B domain YP_001804078.1 contains a cupin, RmlC-type domain YP_001804083.1 contains a mammalian cell entry related domain YP_001804096.1 contains a TRAP transporter solute receptor, TAXI family domain YP_001804100.1 contains a FAD dependent oxidoreductase domain YP_001804103.1 contains a bacterial regulatory protein, MerR domain YP_001804106.1 contains a UspA domain YP_001804107.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001804108.1 contains a nucleic acid-binding, OB-fold domain YP_001804110.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001804115.1 contains a Lambda repressor-like, DNA-binding domain YP_001804118.1 contains DUF820 YP_001804131.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis along with cofH YP_001804139.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001804141.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001804156.1 contains TPR_1 tetratricopeptide repeat domains YP_001804158.1 contains an excinuclease ABC, C subunit, N-terminal domain YP_001804167.1 contains DUF820 YP_001804169.1 contains a TrkA-N domain YP_001804170.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001804172.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001804173.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_001804174.1 contains a von Willebrand factor, type A domain YP_001804176.1 contains a lipase, class 3 domain YP_001804178.1 contains a peptidase M28 domain YP_001804179.1 catalyzes the formation of glutamate from glutamine YP_001804181.1 contains a phytoene dehydrogenase-related protein domain YP_001804184.1 contains a transposase, IS605 OrfB, C-terminal domain YP_001804188.1 contains a mechanosensitive ion channel, MscS domain YP_001804197.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001804198.1 contains a DnaJ N-terminal four helical 'J' domain and TPR-like helical domains YP_001804201.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001804202.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001804203.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001804207.1 contains UPF0016 YP_001804208.1 contains UPF0016 YP_001804216.1 contains a Protein kinase-like domain YP_001804220.1 contains a cyclic nucleotide-binding domain and a winged helix repressor DNA-binding domain YP_001804223.1 contains a cyclic nucleotide-binding domain and a winged helix repressor DNA-binding domain YP_001804224.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001804226.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001804227.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001804231.1 contains an alpha/beta hydrolase fold-1 YP_001804234.1 contains a metallophosphoesterase domain YP_001804235.1 contains a UspA domain YP_001804238.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001804240.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001804241.1 contains a Lambda repressor-like, DNA-binding domain YP_001804245.1 contains DUF497 YP_001804249.1 contains UPF0150 YP_001804258.1 contains a DNA polymerase, beta-like region domain YP_001804261.1 contains UPF0150 YP_001804262.1 contains a YcfA domain YP_001804265.1 contains a Ribbon-helix-helix domain YP_001804266.1 contains a TPR-like helical domain YP_001804276.1 contains a PilT protein, N-terminal domain YP_001804279.1 contains DUF497 YP_001804280.1 contains DUF891 YP_001804282.1 contains DUF752 YP_001804283.1 contains a PilT protein, N-terminal domain YP_001804290.1 contains an alpha amylase, catalytic region YP_001804296.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_001804299.1 contains a Mechanosensitive ion channel, MscS domain YP_001804303.1 contains UPF0054 YP_001804308.1 contains DUF820 YP_001804311.1 contains a soluble quinoprotein glucose dehydrogenase domain YP_001804327.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001804329.1 contains DUF552 YP_001804333.1 contains an Armadillo-like helical domain YP_001804334.1 contains DUF29 YP_001804337.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001804339.1 molecular chaperone YP_001804341.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001804344.1 contains a phosphatase 2C-like domain YP_001804350.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001804355.1 contains DUF1499 YP_001804359.1 contains a secretion protein HlyD domain YP_001804361.1 contains a GCN5-related N-acetyltransferase domain YP_001804366.1 contains UPF0057 YP_001804369.1 low-potential cytochrome c; with PsbO, PsbP, PsbQ, and PsbU makes up the oxygen-evolving complex of photosystem II YP_001804372.1 Rieske protein, with cytochrome b6, cytochrome f, and subunit IV, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001804373.1 cytochrome f, with cytochrome b6, subunit IV, and the Rieske protein, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001804380.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001804381.1 oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis YP_001804389.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001804394.1 contains a mechanosensitive ion channel, MscS domain YP_001804395.1 contains a peptidase M15D, vanX D-ala-D-ala dipeptidase domain YP_001804397.1 contains a TPR-like helical domain YP_001804402.1 contains Penicillin-binding protein and transpeptidase fold domains YP_001804403.1 contains DUF214 YP_001804404.1 contains a secretion protein HlyD domain YP_001804406.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001804418.1 contains a Zinc finger, SWIM-type domain YP_001804422.1 contains a ribbon-helix-helix domain YP_001804423.1 contains DUF497 YP_001804426.1 contains an extracellular ligand-binding receptor domain YP_001804427.1 contains a WD-40 repeat and peptidase C14, caspase catalytic subunit p20 YP_001804428.1 contains a TPR-like helical domain YP_001804432.1 contains a UspA domain YP_001804434.1 contains DUF482 YP_001804436.1 contains a haloacid dehalogenase-like hydrolase domain YP_001804439.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001804440.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001804441.1 contains DUF81 YP_001804444.1 contains a beta-lactamase domain YP_001804445.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001804447.1 contains a serralysin-like metalloprotease, C-terminal domain YP_001804449.1 contains a VCBS repeat YP_001804458.1 contains a methyltransferase type 11 domain YP_001804465.1 contains a MFS 1 domain YP_001804466.1 contains a TonB, C-terminal domain YP_001804475.1 contains a MFS 1 domain YP_001804477.1 contains UPF0150 YP_001804478.1 contains a YcfA domain YP_001804486.1 contains DUF820 YP_001804499.1 contains a glyoxalase/bleomycin resistance protein/dioxygenase domain YP_001804500.1 contains DUF21 and CBS domains YP_001804505.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001804508.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001804510.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001804517.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001804524.1 contains DUF683 YP_001804545.1 contains DUF1568 YP_001804548.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001804553.1 contains a glycosyl transferase, family 2 and Tetratricopeptide TPR_1 domains YP_001804557.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001804561.1 contains a GTP-binding protein, HSR1-related domain YP_001804564.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001804569.1 contains a YcfA domain YP_001804576.1 contains a bacterial regulatory protein, MerR domain YP_001804580.1 type III RuBisCO; involved in carbon fixation YP_001804585.1 contains a GTP-binding protein, HSR1-related domain YP_001804587.1 contains an aminoacyl-tRNA synthetase, class 1a, anticodon-binding domain YP_001804594.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001804599.1 contains glutathione S-transferase, C-terminal-like and Thioredoxin-like fold domains YP_001804603.1 contains DUF192 YP_001804605.1 contains DUF1239 YP_001804615.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001804616.1 Converts isocitrate to alpha ketoglutarate YP_001804619.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001804620.1 contains a CpcD phycobilisome linker-like domain YP_001804623.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001804625.1 contains DUF820 YP_001804630.1 contains DUF433 YP_001804637.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001804638.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001804641.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001804654.1 contains an abortive infection protein domain YP_001804656.1 contains a transcriptional regulator AbrB domain YP_001804658.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001804661.1 contains DUF820 YP_001804665.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001804666.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001804667.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001804670.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001804671.1 contains an EF-Hand type domain YP_001804679.1 cytochrome b6-f complex subunit 5; plastohydroquinone/plastocyanin oxidoreductase; with PetL, PetM and PetN makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001804680.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001804681.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001804682.1 contains a von Willebrand factor, type A domain YP_001804689.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001804694.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001804697.1 contains a DUF1524 RloF domain YP_001804698.1 contains DUF433 YP_001804701.1 contains a UspA domain YP_001804704.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001804710.1 contains DUF29 YP_001804714.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001804715.1 contains a GCN5-related N-acetyltransferase domain YP_001804716.1 contains DUF820 YP_001804719.1 contains DUF820 YP_001804726.1 contains DUF1206 YP_001804731.1 contains DUF88 YP_001804733.1 contains an ATP-binding region, ATPase-like domain YP_001804746.1 contains a metallophosphoesterase domain YP_001804747.1 contains a glycosyl transferase domain YP_001804757.1 contains TPR_1 tetratricopeptide repeat domains YP_001804761.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001804762.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_001804766.1 contains a coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal domain YP_001804774.1 contains a 2Fe-2S Ferredoxin-like domain YP_001804775.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001804776.1 contains a eukaryotic transcription factor, DNA-binding domain YP_001804780.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; involved in carboxysome formation YP_001804781.1 contains DUF433 YP_001804788.1 contains a Cobyrinic acid a,c-diamide synthase domain YP_001804799.1 contains a Cyclic nucleotide-binding domain YP_001804801.1 contains a Penicillin-binding protein, transpeptidase fold domain YP_001804802.1 contains DUF1745 YP_001804805.1 contains a KH, prokaryotic type domain YP_001804806.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001804808.1 4.8-kDa protein; may be involved in assembling and stabilizing of PSII dimers YP_001804810.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001804811.1 contains DUF309 YP_001804813.1 contains DUF389 YP_001804815.1 This is a divergent form of trpE. It is not obvious if it is active in Trp biosynthesis. Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity YP_001804816.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001804823.1 contains a Rhodanese-like domain YP_001804824.1 Rieske protein, with cytochrome b6, cytochrome f, and subunit IV, makes up the large subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001804826.1 contains a Ferritin/ribonucleotide reductase-like domain YP_001804830.1 contains an ABC-1 domain YP_001804834.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001804843.1 contains Anti-Sigma-factor antagonist (STAS) and glycosyl transferase domains YP_001804846.1 contains a peptidase M50 and CBS domain YP_001804849.1 contains UPF0150 YP_001804852.1 contains a phosphoglycerate mutase domain YP_001804857.1 contains a methyltransferase type 11 domain YP_001804861.1 contains DUF820 YP_001804862.1 contains DUF29 YP_001804864.1 contains DUF820 YP_001804873.1 contains a Six-hairpin glycosidase domain YP_001804876.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001804883.1 contains a beta-lactamase-like domain YP_001804884.1 contains a Rhodanese-like domain YP_001804885.1 contains DUF81 YP_001804889.1 contains a GTP-binding signal recognition particle SRP54 helical bundle domain YP_001804890.1 contains a NAD-dependent epimerase/dehydratase domain YP_001804892.1 contains a PEP motif putative anchor, C-terminal domain YP_001804901.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001804902.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001804904.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001804905.1 contains DUF187 YP_001804906.1 contains a serralysin-like metalloprotease, C-terminal domain YP_001804914.1 contains an EF-Hand type domain YP_001804918.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001804919.1 contains a TolB, C-terminal domain YP_001804921.1 contains DUF318, transmembrane YP_001804923.1 contains Molybdopterin dehydrogenase, FAD-binding and CO dehydrogenase flavoprotein, C-terminal domains YP_001804928.1 contains a GCN5-related N-acetyltransferase domain YP_001804929.1 contains aNmrA-like domain YP_001804930.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001804936.1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunit D, with NdhB and NdhF are core membrane components YP_001804942.1 contains an alpha/beta hydrolase fold-1 domain YP_001804949.1 contains DUF815 YP_001804953.1 contains a Prepilin-type cleavage/methylation, N-terminal domain YP_001804957.1 contains a sporulation related domain YP_001804962.1 contains a YiaAB two helix domain YP_001804980.1 contains DUF820 YP_001804983.1 catalyzes the reduction of biliverdin IX-alpha producing (3Z)-phycocyanobilin and oxidized ferredoxin YP_001804990.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001804991.1 contains a GGDEF domain YP_001805000.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls the expression of genes coding cell surface proteins involved in motility and growth on nitrogen YP_001805005.1 Catalyzes the phosphorylation of UMP to UDP YP_001805006.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001805007.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001805008.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; the sigma factors in this cluster are not essential for growth or development; however they may be involved in the expression of nitrogen fixation genes and in dark/light adaption YP_001805012.1 contains a Ion transport 2, bacterial domain YP_001805023.1 contains DUF820 YP_001805031.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001805034.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001805039.1 contains a ribbon-helix-helix domain YP_001805043.1 contains a glycosyl transferase, family 2 domain YP_001805045.1 contains a Thioredoxin-like fold domain YP_001805052.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001805078.1 contains DUF29 YP_001805081.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001805082.1 contains a 2OG-Fe(II) oxygenase domain YP_001805085.1 contains a polynucleotidyl transferase, Ribonuclease H fold domain YP_001805090.1 contains a Mechanosensitive ion channel, MscS domain YP_001805095.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001805097.1 contains a GCN5-related N-acetyltransferase domain YP_001805100.1 catalyzes the formation of pantothenate from pantoate and beta-alanine and the formation of cytidine diphosphate from cytidine monophosphate YP_001805101.1 contains a rare lipoprotein A, bacterial domain YP_001805104.1 contains an alanine dehydrogenase/PNT, N-terminal domain YP_001805105.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001805106.1 contains a GCN5-related N-acetyltransferase domain YP_001805109.1 contains a NAD-dependent epimerase/dehydratase domain YP_001805110.1 contains an aldo/keto reductase domain YP_001805115.1 contains a cobalamin (vitamin B12) biosynthesis CbiX domain YP_001805116.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001805117.1 contains DUF820 YP_001805118.1 contains a PRC-barrel domain YP_001805119.1 contains a UspA domain YP_001805129.1 contains PAS, GGDEF, Response regulator receiver, and GAF domains YP_001805130.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001805133.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001805135.1 contains a Rho termination factor, N-terminal domain YP_001805139.1 contains a succinylglutamate desuccinylase/aspartoacylase domain YP_001805141.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001805147.1 contains a rhomboid-like protein domain YP_001805160.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001805161.1 contains a BRCT domain YP_001805164.1 contains an oxidoreductase domain YP_001805174.1 contains a Phosphopantetheine-binding domain/a Acyl carrier protein-like domain YP_001805176.1 contains a Methyltransferase type 11 domain YP_001805178.1 contains PINc-like Nucleotide binding protein and PhoH domains YP_001805179.1 contains a CHP730 domain YP_001805185.1 contains a KAP P-loop domain YP_001805188.1 contains an Armadillo-like helical domain YP_001805196.1 contains a putative DNA-binding domain YP_001805197.1 contains a DNA methylase N-4/N-6 domain YP_001805209.1 contains a methyltransferase type 11 domain YP_001805212.1 contains a cyclic nucleotide-binding domain and a winged helix repressor DNA-binding domain YP_001805213.1 contains an alpha/beta hydrolase fold-1 domain YP_001805214.1 contains a purine and other phosphorylases, family 1 domain YP_001805230.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001805236.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001805237.1 contains UPF0118 YP_001805245.1 contains DUF202 YP_001805252.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001805258.1 contains DUF202 YP_001805259.1 contains DUF202 YP_001805260.1 contains DUF202 YP_001805281.1 truncated due to frameshift YP_001805285.1 contains UPF0114 YP_001805291.1 contains a mechanosensitive ion channel, MscS domain YP_001805292.1 contains a winged helix repressor DNA-binding domain YP_001805297.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001805300.1 contains a glyoxalase/extradiol/bleomycin resistance/dioxygnease domain YP_001805301.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_001805305.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001805306.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001805307.1 contains DUF820 YP_001805310.1 Transfers the fatty acyl group on membrane lipoproteins YP_001805321.1 contains an Appr-1-p processing domain YP_001805325.1 contains DUF497 YP_001805327.1 contains a ribbon-helix-helix domain YP_001805331.1 contains DUF29 YP_001805337.1 contains glycoside hydrolase, family 19 and peptidase M15A domains YP_001805346.1 contains an endonuclease/exonuclease/phosphatase domain YP_001805347.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001805358.1 contains a Lambda repressor-like, DNA-binding domain YP_001805361.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001805364.1 contains DUF1232 YP_001805365.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001805369.1 contains a polynucleotidyl transferase, Ribonuclease H fold domain YP_001805371.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001805383.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001805386.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001805388.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001805390.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001805392.1 contains DUF1400 YP_001805397.1 contains a phosphate ABC transporter permease fragment YP_001805404.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001805408.1 contains DUF204 YP_001805415.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001805417.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001805418.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001805421.1 contains rfrA family pentapeptide repeat and heat shock protein DnaJ, N-terminal domains YP_001805422.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001805427.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001805429.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001805430.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001805431.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001805432.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001805433.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001805434.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001805435.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001805436.1 one of the stabilizing components for the large ribosomal subunit YP_001805437.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001805438.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001805439.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001805441.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001805442.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001805443.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001805444.1 binds 5S rRNA along with protein L5 and L25 YP_001805445.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001805446.1 late assembly protein YP_001805447.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001805449.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001805451.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001805453.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001805454.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001805455.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001805457.1 forms a direct contact with the tRNA during translation YP_001805459.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001805460.1 contains a glyoxalase/extradiol ring-cleavage dioxygenase domain YP_001805464.1 contains an Acyl carrier protein-like domain YP_001805468.1 contains DUF820 YP_001805469.1 contains DUF29 YP_001805470.1 contains TrkA-N and TrkA-C domains YP_001805471.1 contains DUF820 YP_001805476.1 contains DUF262 and DUF1524 RloF domains YP_001805478.1 contains DUF262 and DUF1524 RloF domains YP_001805479.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001805481.1 contains DUF172 YP_001805484.1 contains DUF990 YP_001805488.1 contains a NAD-dependent epimerase/dehydratase domain YP_001805489.2 catalyzes the phosphorylation of NAD to NADP YP_001805491.1 main replicative polymerase; these cyanobacterial enzymes contain C-terminal split inteins; they are joined with the C-terminal fragments that contain N-terminal inteins that are encoded elsewhere in the genome YP_001805495.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001805497.1 contains a Lipolytic enzyme, G-D-S-L domain YP_001805501.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001805502.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001805503.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001805504.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001805505.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001805506.1 contains HesB/YadR/YfhF domains YP_001805509.1 contains UPF0004 YP_001805513.1 contains a YcaO_like domain YP_001805526.1 contains a glucose-methanol-choline oxidoreductase domain YP_001805530.1 contains DUF477 YP_001805532.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001805533.1 contains a peptidase M50 and CBS domain YP_001805534.1 contains a cobyrinic acid a,c-diamide synthase domain YP_001805537.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001805541.1 contains a methyltransferase type 11 domain YP_001805548.1 contains a Lipase, class 2 domain YP_001805549.1 contains a hydratase/decarboxylase domain YP_001805550.1 contains a glycosyl transferase, family 39 and a TPR-like helical domain YP_001805553.1 contains peptidoglycan-binding domain 1 YP_001805554.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001805556.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001805558.1 contains a Like-Sm ribonucleoprotein-related protein core domain YP_001805560.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001805563.1 contains a methyltransferase type 11 domain YP_001805566.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001805573.1 contains DUF318, transmembrane YP_001805575.1 contains a Cyclic nucleotide-binding domain YP_001805576.1 contains a Cyclic nucleotide-binding domain YP_001805580.2 contains a CBS domain YP_001805584.1 contains an ABC-1 domain YP_001805589.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001805590.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001805591.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, SMAD/FHA domain, and a PAS fold domain YP_001805598.1 contains DUF1232 YP_001805602.1 contains a polysaccharide export protein domain YP_001805603.1 contains a CheW-like domain YP_001805614.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001805616.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001805619.1 contains a GCN5-related N-acetyltransferase domain YP_001805620.1 contains a NLP/P60 domain YP_001805628.1 contains UPF0052 and CofD domains YP_001805633.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001805634.1 contains a UspA domain YP_001805635.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001805636.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001805637.1 contains a neurotransmitter-gated ion-channel domain YP_001805640.1 contains a PilT protein, N-terminal domain YP_001805641.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_001805647.1 contains DUF820 YP_001805651.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001805663.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001805664.1 contains DUF29 YP_001805667.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001805668.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001805672.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001805673.1 contains DUF29 YP_001805680.1 contains DUF82 YP_001805682.1 catalyzes the formation of precorrin-8x from precorrin-6y YP_001805684.1 contains DUF820 YP_001805686.1 contains a UspA domain YP_001805700.1 involved in start site selection during the initiation of translation YP_001805708.1 contains a GUN4-like domain YP_001805710.1 contains a radical SAM domain YP_001805713.1 Shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain YP_001805714.1 contains DUF512 and PDZ/DHR/GLGF domains YP_001805716.1 contains an O-antigen polymerase domain YP_001805718.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001805720.1 contains a FAD linked oxidase, N-terminal domain YP_001805722.1 contains a cobalamin (vitamin B12) biosynthesis CbiX domain YP_001805728.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001805732.1 contains a CheW-like domain YP_001805735.1 contains Helicase, C-terminal and DEAD/DEAH box helicase, N-terminal domains YP_001805738.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001805739.1 Stabilizes the interaction between PsaC and the photosystem I core YP_001805741.1 contains an aldo/keto reductase domain YP_001805747.1 contains DUF820 YP_001805749.1 contains a polynucleotidyl transferase, Ribonuclease H fold domain YP_001805751.1 contains a Band 7 domain YP_001805755.1 contains selenide water dikinase and FAD-dependent pyridine nucleotide-disulphide oxidoreductase domains YP_001805756.1 contains FAD dependent oxidoreductase and Phytoene dehydrogenase-related domains YP_001805760.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001805762.1 contains DUF86 YP_001805763.1 contains a DNA polymerase, beta-like region domain YP_001805766.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001805768.1 involved in de novo purine biosynthesis YP_001805770.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001805772.1 catalyzes the formation of Mg-protoporphyrin IX from protoporphyrin IX and Mg(2+); first committed step of chlorophyll biosynthesis YP_001805773.1 contains a HNH nuclease domain YP_001805778.1 contains UPF0150 YP_001805780.1 contains DUF820 YP_001805782.1 contains UPF0004, longator protein 3/MiaB/NifB, and Radical SAM domains YP_001805784.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001805786.1 contains DUF433 YP_001805792.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001805795.1 contains a Mechanosensitive ion channel, MscS domain YP_001805796.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001805798.1 contains a SMAD/FHA domain YP_001805812.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001805814.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001805815.1 negatively supercoils closed circular double-stranded DNA YP_001805822.1 contains a peptidase M52, hydrogen uptake protein domain YP_001805825.1 contains DUF820 YP_001805826.1 oxidative; catalyzes the formation of divinylprotochlorophyllide from magnesium-protoporphyrin IX 13-monomethyl ester in isocyclic ring formation in chlorophyll biosynthesis YP_001805852.1 binds and unfolds substrates as part of the ClpXP protease YP_001805857.1 contains a six-hairpin glycosidase domain YP_001805860.1 cytochrome b6-f complex subunit 8; with PetL, PetG and PetM makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001805868.1 contains a UbiA prenyltransferase domain YP_001805869.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001805871.1 contains a Type I phosphodiesterase/nucleotide pyrophosphatase domain YP_001805874.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001805877.1 catalyzes the formation of tyrosine from arogenate YP_001805879.1 contains DUF87 YP_001805883.1 contains a TPR-like helical domain YP_001805887.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001805892.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001805893.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate YP_001805897.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001805898.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001805899.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001805900.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_001805901.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001805902.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001805903.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001805914.1 contains a GCN5-related N-acetyltransferase domain YP_001805916.1 contains an Armadillo-like helical domain YP_001805918.1 contains an alpha/beta hydrolase fold-1 domain YP_001805919.1 contains a MFS 1 domain YP_001805920.1 contains a Glutathione S-transferase, C-terminal-like domain and a Thioredoxin-like fold domain YP_001805922.1 contains a lambda repressor-like, DNA-binding domain YP_001805923.1 contains a cytochrome C region domain YP_001805926.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP YP_001805930.1 contains a dimeric alpha-beta barrel domain YP_001805932.1 may be involved in binding plastoquinone and maintaining PSII dimers YP_001805933.1 contains a beta-lactamase-like domain YP_001805939.1 contains an allergen V5/Tpx-1 related domain YP_001805944.1 contains DUF820 YP_001805946.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production YP_001805948.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001805953.1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis along with cofG YP_001805958.1 contains a CheW-like domain YP_001805959.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001805960.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001805965.1 contains an ASPIC/UnbV domain YP_001805966.1 contains a Sulfotransferase domain YP_001805968.1 contains a nitroreductase domain YP_001805970.1 contains a heparan sulphate 6-sulfotransferase domain YP_001805976.1 contains a phage integrase-like, catalytic core domain YP_001805977.1 contains a DNA breaking-rejoining enzyme, catalytic core domain YP_001805981.1 contains a dynamin domain YP_001805988.1 contains a Mechanosensitive ion channel, MscS domain YP_001805996.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001805999.1 contains a Mechanosensitive ion channel, MscS domain YP_001806005.1 Essential for recycling GMP and indirectly, cGMP YP_001806010.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001806014.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001806015.1 contains a phospholipid/glycerol acyltransferase domain YP_001806019.1 contains DUF990 YP_001806022.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001806024.1 contains a Mo-dependent nitrogenase, C-terminal domain YP_001806030.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001806039.1 contains Endonuclease/exonuclease/phosphatase and Serralysin-like metalloprotease, C-terminal domains YP_001806040.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001806041.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001806042.1 contains an extracellular ligand-binding receptor domain YP_001806053.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001806055.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001806059.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001806060.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001806062.1 contains photosynthetic reaction center H-chain cytoplasmic and CHP2271 C-terminal domains YP_001806064.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001806065.1 contains an EAL signaling domain YP_001806067.1 contains a GGDEF domain, Forkhead-associated domain, EAL domain, and SMAD/FHA domain YP_001806072.1 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms YP_001806074.1 contains a WD-repeat, a PAS region and a response regulator receiver domain YP_001806075.1 contains DUF820 YP_001806076.1 contains a coenzyme F420 hydrogenase/dehydrogenase beta subunit domain YP_001806089.1 contains Serralysin-like metalloprotease, C-terminal and Peptidase, archaeal and bacterial C-terminal domains YP_001806091.1 contains DUF156 YP_001806093.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001806094.1 controls the interaction of photosystem II cores with light-harvesting antenna YP_001806100.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001806106.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001806107.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001806108.1 contains a GUN4-like domain YP_001806109.1 contains a secretion protein HlyD domain YP_001806121.1 contains an OmpA/MotB domain YP_001806123.1 contains a GGDEF domain, EAL domain, and PAS fold-3 domain YP_001806130.1 acts as a promotor non-specific transcription repressor YP_001806131.1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradien YP_001806132.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001806136.1 contains UPF0118 YP_001806137.1 main replicative polymerase YP_001806140.1 contains RNA methylase and THUMP domains YP_001806141.1 contains a bacterial regulatory protein GntR, HTH domain YP_001806145.1 contains a metallophosphoesterase domain YP_001806149.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001806152.1 contains a beta-lactamase-like domain YP_001806155.1 contains a peptidase U62, modulator of DNA gyrase domain YP_001806161.1 contains a glycosyl transferase, family 2 domain YP_001806162.1 contains DUF422 YP_001806163.1 contains a RDD domain YP_001806164.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001806168.1 contains DUF497 YP_001806169.1 contains DUF820 YP_001806171.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001806172.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001806174.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001806176.1 Ycf7; cytochrome b6-f complex subunit 6; with PetG, PetM and PetN makes up the small subunit of the cytochrome b6-f complex; cytochrome b6-f mediates electron transfer between photosystem II and photosystem I YP_001806181.1 contains DUF955 YP_001806187.1 contains a HNH endonuclease domain YP_001806190.1 contains a heat shock protein DnaJ, N-terminal domain YP_001806192.1 contains a poxvirus D5 protein domain YP_001806194.1 contains a lambda repressor-like, DNA-binding domain YP_001806205.1 contains a DnaJ N-terminal four helical 'J' domain YP_001806207.1 contains a DEAD/DEAH box helicase domain YP_001806217.1 contains a soluble quinoprotein glucose dehydrogenase domain YP_001806233.1 contains FG-GAP repeat domains YP_001806235.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001806238.1 contains a high-affinity nickel-transporter domain YP_001806246.1 contains a Cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001806247.1 contains a Cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001806248.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001806249.1 contains DUF820 YP_001806255.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001806256.1 contains a Cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001806258.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001806260.1 contains a FAD-dependent pyridine nucleotide-disulphide oxidoreductase domain YP_001806261.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001806263.1 contains a phosphoesterase MJ0912 domain YP_001806265.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001806270.1 contains a cobalamin (vitamin B12) biosynthesis domain, cobW domain YP_001806276.1 contains a FAD-dependent pyridine nucleotide-disulphide oxidoreductase domain YP_001806282.1 contains an Excisionase/Xis, DNA-binding domain YP_001806284.1 contains serralysin-like metalloprotease, C-terminal and Hemolysin-type calcium-binding region domains YP_001806285.1 contains a hemolysin-type calcium-binding region domain YP_001806295.1 contains a cobyrinic acid a,c-diamide synthase domain YP_001806305.1 contains an allergen V5/Tpx-1 related domain YP_001806326.1 contains a CHP730 domain YP_001806327.1 contains PINc-like Nucleotide binding protein and PhoH domains YP_001806336.1 contains a ribbon-helix-helix domain YP_001806337.1 contains a Type I restriction enzyme R protein, N terminus domain YP_001806338.1 contains DUF820 YP_001806342.1 contains a TPR-like helical domain YP_001806343.1 contains a filamentous haemagglutinin, N-terminal domain YP_001806344.1 contains a polypeptide-transport-associated, ShlB-type domain YP_001806345.1 contains a ribbon-helix-helix domain YP_001806356.1 contains an ATP-binding region, ATPase-like domain YP_001806360.1 contains DUF497 YP_001806363.1 contains a polynucleotidyl transferase, Ribonuclease H fold domain YP_001806379.1 contains DUF497 YP_001806392.1 contains a ribbon-helix-helix domain YP_001806393.1 contains a relaxase/mobilization nuclease domain YP_001806408.1 contains Helicase, C-terminal and DEAD/DEAH box helicase, N-terminal domains YP_001806410.1 contains a PilT protein, N-terminal domain YP_001806414.1 contains DUF1568 YP_001806415.1 contains a N6 adenine-specific DNA methyltransferase, N12 class domain YP_001806417.1 contains Helicase, C-terminal, Type III restriction enzyme, res subunit and DEAD/DEAH box helicase, N-terminal domains YP_001806424.1 contains a TPR-like helical domain YP_001806430.1 contains a TRAG protein domain YP_001806433.1 contains a peptidase M23B YP_001806447.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001806448.1 contains a GCN5-related N-acetyltransferase domain YP_001806453.1 contains a Lambda repressor-like, DNA-binding domain YP_001806454.1 contains a CHASE2 extracellular sensory domain YP_001806458.1 contains a filamentous haemagglutinin, N-terminal domain YP_001806459.1 contains a bacterial surface antigen (D15) and Polypeptide-transport-associated, ShlB-type domain YP_001806474.1 contains a HNH endonuclease domain YP_001806477.1 contains PilT protein, N-terminal and DUF132 domains YP_001806507.1 contains DUF820 YP_001806519.1 contains aUbiA prenyltransferase domain YP_001806534.1 contains DSBA oxidoreductase and Thioredoxin fold domains YP_001806537.1 contains a TrkA-N domain YP_001806538.1 contains DUF123 YP_001806548.1 contains a GCN5-related N-acetyltransferase domain YP_001806552.1 contains a ribbon-helix-helix domain YP_001806555.1 contains low-density lipoprotein receptor YWTD repeat domains YP_001806557.1 contains a PilT protein, N-terminal domain YP_001806562.1 contains DUF457, transmembrane YP_001806563.1 contains a DNA/RNA non-specific endonuclease domain YP_001806577.1 contains a CHAD domain YP_001806584.1 contains a Cyclic nucleotide-binding domain YP_001806588.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001806590.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001806591.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001806593.1 contains a von Willebrand factor, type A domain YP_001806594.1 contains a Cyclic nucleotide-binding domain YP_001806595.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001806608.1 contains a TrkA-N domain YP_001806625.1 contains a poxvirus D5 protein domain