-- dump date 20140619_075604 -- class Genbank::CDS -- table cds_note -- id note YP_001905924.1 silverDB:46p00001 YP_001905925.1 silverDB:46p00002 YP_001905926.1 silverDB:46p00003 YP_001905927.1 silverDB:46p00004 YP_001905928.1 silverDB:46p00005 YP_001905929.1 silverDB:46p00006 YP_001905930.1 silverDB:46p00007 YP_001905931.1 silverDB:46p00008 YP_001905932.1 silverDB:46p00012 YP_001905933.1 silverDB:46p00013 YP_001905934.1 silverDB:46p00014 YP_001905935.1 silverDB:46p00015 YP_001905936.1 silverDB:46p00017 YP_001905937.1 silverDB:46p00018 YP_001905938.1 silverDB:46p00019 YP_001905939.1 silverDB:46p00024 YP_001905940.1 silverDB:46p00026 YP_001905941.1 silverDB:46p00027 YP_001905942.1 silverDB:46p00033 YP_001905943.1 silverDB:46p00034 YP_001905944.1 silverDB:46p00035 YP_001905945.1 RepE; RepFIB YP_001905946.1 silverDB:46p00037 YP_001905947.1 silverDB:46p00038 YP_001905948.1 silverDB:46p00041 YP_001905949.1 silverDB:46p00042 YP_001905950.1 silverDB:46p00044 YP_001905951.1 silverDB:46p00045 YP_001905952.1 silverDB:46p00046 YP_001905953.1 silverDB:46p00047 YP_001905954.1 silverDB:46p00048 YP_001905955.1 silverDB:46p00049 YP_001905956.1 silverDB:46p00050 YP_001905957.1 silverDB:46p00051 YP_001905958.1 silverDB:46p00052 YP_001905959.1 silverDB:46p00053 YP_001905960.1 silverDB:46p00054 YP_001905961.1 silverDB:46p00055 YP_001905962.1 silverDB:46p00056 YP_001905963.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001905964.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001905965.1 silverDB:etchr00003 YP_001905966.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001905967.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001905968.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001905969.1 silverDB:etchr00007 YP_001905970.1 silverDB:etchr00008 YP_001905971.1 silverDB:etchr00009 YP_001905972.1 silverDB:etchr00010 YP_001905973.1 silverDB:etchr00011 YP_001905974.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_001905975.1 silverDB:etchr00013 YP_001905976.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001905977.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001905978.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001905979.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001905980.1 DNA-binding transcriptional repressor of ribose metabolism YP_001905981.1 silverDB:etchr00019 YP_001905982.1 silverDB:etchr00020 YP_001905983.1 silverDB:etchr00021 YP_001905984.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001905985.1 silverDB:etchr00023 YP_001905986.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001905987.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001905988.1 silverDB:etchr00026 YP_001905989.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001905990.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001905991.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001905992.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001905993.1 silverDB:etchr00031 YP_001905994.1 silverDB:etchr00032 YP_001905995.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001905996.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001905997.1 silverDB:etchr00035 YP_001905998.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001905999.1 silverDB:etchr00037 YP_001906000.1 silverDB:etchr00038 YP_001906001.1 catalyzes branch migration in Holliday junction intermediates YP_001906002.1 specifically modifies tRNA at position G18 YP_001906003.1 silverDB:etchr00041 YP_001906004.1 silverDB:etchr00042 YP_001906005.1 Essential for recycling GMP and indirectly, cGMP YP_001906006.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001906007.1 silverDB:etchr00045 YP_001906008.1 silverDB:etchr00046 YP_001906009.1 silverDB:etchr00047 YP_001906010.1 silverDB:etchr00048 YP_001906011.1 silverDB:etchr00049 YP_001906012.1 silverDB:etchr00050 YP_001906013.1 silverDB:etchr00051 YP_001906014.1 silverDB:etchr00055 YP_001906015.1 silverDB:etchr00056 YP_001906016.1 silverDB:etchr00058 YP_001906017.1 silverDB:etchr00059 YP_001906018.1 silverDB:etchr00060 YP_001906019.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001906020.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001906021.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001906022.1 catalyzes the formation of dUMP from dUTP YP_001906023.1 silverDB:etchr00065 YP_001906024.1 silverDB:etchr00066 YP_001906025.1 required for 70S ribosome assembly YP_001906026.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001906027.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001906028.1 silverDB:etchr00069 YP_001906029.1 silverDB:etchr00070 YP_001906030.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001906031.1 silverDB:etchr00072 YP_001906032.1 silverDB:etchr00073 YP_001906033.1 silverDB:etchr00074 YP_001906034.1 silverDB:etchr00075 YP_001906035.1 silverDB:etchr00076 YP_001906036.1 silverDB:etchr00077 YP_001906037.1 silverDB:etchr00078 YP_001906038.1 silverDB:etchr00079 YP_001906039.1 silverDB:etchr00080 YP_001906040.1 silverDB:etchr00081 YP_001906041.1 silverDB:etchr00082 YP_001906042.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001906043.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001906044.1 silverDB:etchr00085 YP_001906045.1 silverDB:etchr00086 YP_001906046.1 silverDB:etchr00087 YP_001906047.1 silverDB:etchr00088 YP_001906048.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001906049.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001906050.1 catalyzes the O-acetylation of serine YP_001906051.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001906052.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001906053.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001906054.1 silverDB:etchr00095 YP_001906055.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001906056.1 silverDB:etchr00097 YP_001906057.1 silverDB:etchr00098 YP_001906058.1 silverDB:etchr00099 YP_001906059.1 silverDB:etchr00100 YP_001906060.1 silverDB:etchr00101 YP_001906061.1 silverDB:etchr00102 YP_001906062.1 silverDB:etchr00103 YP_001906063.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001906064.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001906065.1 silverDB:etchr00106 YP_001906066.1 silverDB:etchr00107 YP_001906067.1 silverDB:etchr00108 YP_001906068.1 silverDB:etchr00109 YP_001906069.1 multidrug efflux protein involved in adaptation to low energy shock YP_001906070.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001906071.1 silverDB:etchr00112 YP_001906072.1 silverDB:etchr00113 YP_001906073.1 silverDB:etchr00114 YP_001906074.1 silverDB:etchr00115 YP_001906075.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001906076.1 heat shock protein involved in degradation of misfolded proteins YP_001906077.1 heat shock protein involved in degradation of misfolded proteins YP_001906078.1 silverDB:etchr00119 YP_001906079.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001906080.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001906081.1 silverDB:etchr00122 YP_001906082.1 silverDB:etchr00123 YP_001906083.1 silverDB:etchr00124 YP_001906084.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001906085.1 silverDB:etchr00126 YP_001906086.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001906087.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001906088.1 silverDB:etchr00131 YP_001906089.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001906090.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001906091.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001906092.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001906093.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001906094.1 silverDB:etchr00137 YP_001906095.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001906096.1 catalyzes the conversion of NADPH to NADH YP_001906097.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001906098.1 silverDB:etchr00141 YP_001906099.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001906100.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001906101.1 silverDB:etchr00144 YP_001906102.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001906103.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001906104.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001906105.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001906106.1 Modulates Rho-dependent transcription termination YP_001906107.1 silverDB:etchr00150 YP_001906108.1 silverDB:etchr00151 YP_001906109.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001906110.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001906111.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001906112.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001906113.1 silverDB:etchr00156 YP_001906114.1 silverDB:etchr00157 YP_001906115.1 silverDB:etchr00160 YP_001906116.1 silverDB:etchr00161 YP_001906117.1 silverDB:etchr00162 YP_001906118.1 silverDB:etchr00163 YP_001906119.1 silverDB:etchr00164 YP_001906120.1 silverDB:etchr00165 YP_001906121.1 silverDB:etchr00166 YP_001906122.1 silverDB:etchr00167 YP_001906123.1 silverDB:etchr00168 YP_001906124.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001906125.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001906126.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001906127.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001906128.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001906129.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001906130.1 silverDB:etchr00175 YP_001906131.1 histone-like DNA-binding protein YP_001906132.1 silverDB:etchr00177 YP_001906133.1 silverDB:etchr00178 YP_001906134.1 involved in de novo purine biosynthesis YP_001906135.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001906136.1 silverDB:etchr00181 YP_001906137.1 silverDB:etchr00182 YP_001906138.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001906139.1 silverDB:etchr00184 YP_001906140.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001906141.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001906142.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001906143.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001906144.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001906145.1 silverDB:etchr00190 YP_001906146.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001906147.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001906148.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001906149.1 silverDB:etchr00194 YP_001906150.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001906151.1 silverDB:etchr00196 YP_001906152.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001906153.1 silverDB:etchr00198 YP_001906154.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001906155.1 silverDB:etchr00200 YP_001906156.1 silverDB:etchr00201 YP_001906157.1 silverDB:etchr00202 YP_001906158.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001906159.1 silverDB:etchr00204 YP_001906160.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001906161.1 enterobacterial common antigen polymerase YP_001906162.1 silverDB:etchr00207 YP_001906163.1 silverDB:etchr00208 YP_001906164.1 silverDB:etchr00209 YP_001906165.1 silverDB:etchr00210 YP_001906166.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001906167.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001906168.1 silverDB:etchr00213 YP_001906169.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001906170.1 silverDB:etchr00215 YP_001906171.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001906172.1 silverDB:etchr00217 YP_001906173.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001906174.1 responsible for the influx of magnesium ions YP_001906175.1 silverDB:etchr00220 YP_001906176.1 catalyzes the hydrolysis of phosphatidylcholine YP_001906177.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001906178.1 silverDB:etchr00223 YP_001906179.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001906180.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001906181.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001906182.1 silverDB:etchr00227 YP_001906183.1 silverDB:etchr00228 YP_001906184.1 silverDB:etchr00229 YP_001906185.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001906186.1 silverDB:etchr00231 YP_001906187.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001906188.1 silverDB:etchr00233 YP_001906189.1 silverDB:etchr00234 YP_001906190.1 silverDB:etchr00235 YP_001906191.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001906192.1 silverDB:etchr00237 YP_001906193.1 silverDB:etchr00238 YP_001906194.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001906195.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001906196.1 silverDB:etchr00241 YP_001906197.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001906198.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001906199.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001906200.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001906201.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001906202.1 silverDB:etchr00247 YP_001906203.1 silverDB:etchr00248 YP_001906204.1 silverDB:etchr00249 YP_001906205.1 silverDB:etchr00250 YP_001906206.1 silverDB:etchr00251 YP_001906207.1 silverDB:etchr00252 YP_001906208.1 silverDB:etchr00253 YP_001906209.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001906210.1 silverDB:etchr00255 YP_001906211.1 silverDB:etchr00256 YP_001906212.1 silverDB:etchr00257 YP_001906213.1 silverDB:etchr00258 YP_001906214.1 silverDB:etchr00259 YP_001906215.1 silverDB:etchr00260 YP_001906216.1 silverDB:etchr00261 YP_001906217.1 silverDB:etchr00262 YP_001906218.1 silverDB:etchr00263 YP_001906219.1 silverDB:etchr00264 YP_001906220.1 silverDB:etchr00265 YP_001906221.1 silverDB:etchr00266 YP_001906222.1 silverDB:etchr00267 YP_001906223.1 silverDB:etchr00268 YP_001906224.1 silverDB:etchr00269 YP_001906225.1 silverDB:etchr00270 YP_001906226.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001906227.1 silverDB:etchr00272 YP_001906228.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001906229.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001906230.1 silverDB:etchr00275 YP_001906231.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001906232.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001906233.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001906234.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001906235.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001906236.1 silverDB:etchr00281 YP_001906237.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001906238.1 functions in MreBCD complex in some organisms YP_001906239.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001906240.1 part of cell wall structural complex MreBCD; transmembrane component YP_001906241.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001906242.1 involved in the processing of the 5'end of 16S rRNA YP_001906243.1 silverDB:etchr00288 YP_001906244.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001906245.1 silverDB:etchr00290 YP_001906246.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001906247.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001906248.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001906249.1 silverDB:etchr00294 YP_001906250.1 silverDB:etchr00295 YP_001906251.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001906252.1 oxidizes malate to oxaloacetate YP_001906253.1 silverDB:etchr00298 YP_001906254.1 silverDB:etchr00299 YP_001906255.1 silverDB:etchr00300 YP_001906256.1 silverDB:etchr00301 YP_001906257.1 silverDB:etchr00302 YP_001906258.1 forms a direct contact with the tRNA during translation YP_001906259.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001906260.1 silverDB:etchr00305 YP_001906261.1 silverDB:etchr00306 YP_001906262.1 silverDB:etchr00307 YP_001906263.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001906264.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001906265.1 silverDB:etchr00310 YP_001906266.1 silverDB:etchr00311 YP_001906267.1 silverDB:etchr00312 YP_001906268.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001906269.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001906270.1 silverDB:etchr00315 YP_001906271.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001906272.1 silverDB:etchr00317 YP_001906273.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001906274.1 silverDB:etchr00319 YP_001906275.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001906276.1 ATP-binding subunit of a ABC toluene efflux transporter YP_001906277.1 silverDB:etchr00322 YP_001906278.1 silverDB:etchr00323 YP_001906279.1 silverDB:etchr00324 YP_001906280.1 silverDB:etchr00325 YP_001906281.1 silverDB:etchr00326 YP_001906282.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001906283.1 silverDB:etchr00328 YP_001906284.1 silverDB:etchr00329 YP_001906285.1 silverDB:etchr00330 YP_001906286.1 involved in the peptidyltransferase reaction during translation YP_001906287.1 silverDB:etchr00332 YP_001906288.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001906289.1 silverDB:etchr00334 YP_001906290.1 response regulator in two-component regulatory system with BasS YP_001906291.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001906292.1 silverDB:etchr00337 YP_001906293.1 silverDB:etchr00338 YP_001906294.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001906295.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001906296.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001906297.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001906298.1 silverDB:etchr00343 YP_001906299.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001906300.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001906301.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001906302.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001906303.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001906304.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001906305.1 silverDB:etchr00350 YP_001906306.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001906307.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001906308.1 silverDB:etchr00353 YP_001906309.1 silverDB:etchr00354 YP_001906310.1 silverDB:etchr00355 YP_001906311.1 silverDB:etchr00356 YP_001906312.1 silverDB:etchr00357 YP_001906313.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001906314.1 silverDB:etchr00359 YP_001906315.1 silverDB:etchr00360 YP_001906316.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001906317.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001906318.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001906319.1 silverDB:etchr00365 YP_001906320.1 silverDB:etchr00366 YP_001906321.1 silverDB:etchr00367 YP_001906322.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001906323.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001906324.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001906325.1 silverDB:etchr00371 YP_001906326.1 silverDB:etchr00372 YP_001906327.1 silverDB:etchr00373 YP_001906328.1 silverDB:etchr00374 YP_001906329.1 silverDB:etchr00375 YP_001906330.1 silverDB:etchr00376 YP_001906331.1 silverDB:etchr00377 YP_001906332.1 silverDB:etchr00378 YP_001906333.1 silverDB:etchr00379 YP_001906334.1 silverDB:etchr00380 YP_001906335.1 silverDB:etchr00381 YP_001906336.1 silverDB:etchr00382 YP_001906337.1 silverDB:etchr00383 YP_001906338.1 silverDB:etchr00384 YP_001906339.1 silverDB:etchr00385 YP_001906340.1 silverDB:etchr00386 YP_001906341.1 silverDB:etchr00387 YP_001906342.1 silverDB:etchr00388 YP_001906343.1 silverDB:etchr00389 YP_001906344.1 silverDB:etchr00390 YP_001906345.1 silverDB:etchr00391 YP_001906346.1 silverDB:etchr00393 YP_001906347.1 silverDB:etchr00396 YP_001906348.1 silverDB:etchr00397 YP_001906349.1 silverDB:etchr00398 YP_001906350.1 silverDB:etchr00399 YP_001906351.1 silverDB:etchr00400 YP_001906352.1 silverDB:etchr00401 YP_001906353.1 silverDB:etchr00402 YP_001906354.1 silverDB:etchr00403 YP_001906355.1 silverDB:etchr00404 YP_001906356.1 silverDB:etchr00405 YP_001906357.1 silverDB:etchr00406 YP_001906358.1 silverDB:etchr00407 YP_001906359.1 silverDB:etchr00408 YP_001906360.1 silverDB:etchr00409 YP_001906361.1 silverDB:etchr00410 YP_001906362.1 this protein has no known enzymatic function YP_001906363.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001906364.1 silverDB:etchr00413 YP_001906365.1 silverDB:etchr00414 YP_001906366.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001906367.1 synthesizes RNA primers at the replication forks YP_001906368.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001906369.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001906370.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001906371.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001906372.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001906373.1 silverDB:etchr00422 YP_001906374.1 silverDB:etchr00423 YP_001906375.1 silverDB:etchr00424 YP_001906376.1 silverDB:etchr00425 YP_001906377.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001906378.1 silverDB:etchr00427 YP_001906379.1 silverDB:etchr00428 YP_001906380.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001906381.1 silverDB:etchr00430 YP_001906382.1 silverDB:etchr00431 YP_001906383.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001906384.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001906385.1 silverDB:etchr00434 YP_001906386.1 silverDB:etchr00435 YP_001906387.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001906388.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001906389.1 silverDB:etchr00438 YP_001906390.1 silverDB:etchr00439 YP_001906391.1 silverDB:etchr00440 YP_001906392.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001906393.1 silverDB:etchr00442 YP_001906394.1 silverDB:etchr00443 YP_001906395.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001906396.1 silverDB:etchr00445 YP_001906397.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_001906398.1 silverDB:etchr00447 YP_001906399.1 silverDB:etchr00448 YP_001906400.1 catalyzes the formation of L-homocysteine from cystathionine YP_001906401.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001906402.1 silverDB:etchr00451 YP_001906403.1 silverDB:etchr00452 YP_001906404.1 silverDB:etchr00453 YP_001906405.1 silverDB:etchr00454 YP_001906406.1 silverDB:etchr00455 YP_001906407.1 silverDB:etchr00456 YP_001906408.1 silverDB:etchr00457 YP_001906409.1 silverDB:etchr00458 YP_001906410.1 silverDB:etchr00459 YP_001906411.1 silverDB:etchr00460 YP_001906412.1 silverDB:etchr00461 YP_001906413.1 silverDB:etchr00462 YP_001906414.1 silverDB:etchr00463 YP_001906415.1 silverDB:etchr00464 YP_001906416.1 silverDB:etchr00465 YP_001906417.1 silverDB:etchr00466 YP_001906418.1 silverDB:etchr00467 YP_001906419.1 silverDB:etchr00468 YP_001906420.1 silverDB:etchr00469 YP_001906421.1 silverDB:etchr00470 YP_001906422.1 silverDB:etchr00471 YP_001906423.1 silverDB:etchr00472 YP_001906424.1 silverDB:etchr00473 YP_001906425.1 silverDB:etchr00475 YP_001906426.1 silverDB:etchr00476 YP_001906427.1 silverDB:etchr00477 YP_001906428.1 silverDB:etchr00478 YP_001906429.1 silverDB:etchr00479 YP_001906430.1 silverDB:etchr00480 YP_001906431.1 silverDB:etchr00481 YP_001906432.1 silverDB:etchr00482 YP_001906433.1 silverDB:etchr00483 YP_001906434.1 silverDB:etchr00484 YP_001906435.1 silverDB:etchr00485 YP_001906436.1 silverDB:etchr00486 YP_001906437.1 silverDB:etchr00487 YP_001906438.1 silverDB:etchr00488 YP_001906439.1 silverDB:etchr00489 YP_001906440.1 silverDB:etchr00491 YP_001906441.1 silverDB:etchr00492 YP_001906442.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001906443.1 silverDB:etchr00494 YP_001906444.1 silverDB:etchr00495 YP_001906445.1 unknown function; when overproduced it confers drug-resistance YP_001906446.1 silverDB:etchr00497 YP_001906447.1 silverDB:etchr00498 YP_001906448.1 silverDB:etchr00499 YP_001906449.1 silverDB:etchr00500 YP_001906450.1 silverDB:etchr00501 YP_001906451.1 silverDB:etchr00502 YP_001906452.1 silverDB:etchr00504 YP_001906453.1 silverDB:etchr00505 YP_001906454.1 silverDB:etchr00506 YP_001906455.1 silverDB:etchr00507 YP_001906456.1 silverDB:etchr00508 YP_001906457.1 inactivates vertebrate C-type lysozyme YP_001906458.1 silverDB:etchr00510 YP_001906459.1 silverDB:etchr00511 YP_001906460.1 silverDB:etchr00512 YP_001906461.1 silverDB:etchr00513 YP_001906462.1 silverDB:etchr00514 YP_001906463.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001906464.1 silverDB:etchr00516 YP_001906465.1 silverDB:etchr00517 YP_001906466.1 silverDB:etchr00518 YP_001906467.1 silverDB:etchr00519 YP_001906468.1 silverDB:etchr00520 YP_001906469.1 silverDB:etchr00521 YP_001906470.1 silverDB:etchr00522 YP_001906471.1 silverDB:etchr00523 YP_001906472.1 silverDB:etchr00524 YP_001906473.1 silverDB:etchr00525 YP_001906474.1 silverDB:etchr00526 YP_001906475.1 silverDB:etchr00527 YP_001906476.1 silverDB:etchr00528 YP_001906477.1 silverDB:etchr00529 YP_001906478.1 silverDB:etchr00530 YP_001906479.1 silverDB:etchr00531 YP_001906480.1 silverDB:etchr00532 YP_001906481.1 silverDB:etchr00533 YP_001906482.1 silverDB:etchr00534 YP_001906483.1 silverDB:etchr00535 YP_001906484.1 silverDB:etchr00536 YP_001906485.1 silverDB:etchr00537 YP_001906486.1 silverDB:etchr00538 YP_001906487.1 silverDB:etchr00539 YP_001906488.1 silverDB:etchr00540 YP_001906489.1 silverDB:etchr00541 YP_001906490.1 silverDB:etchr00542 YP_001906491.1 silverDB:etchr00543 YP_001906492.1 silverDB:etchr00544 YP_001906493.1 silverDB:etchr00545 YP_001906494.1 silverDB:etchr00546 YP_001906495.1 silverDB:etchr00547 YP_001906496.1 silverDB:etchr00548 YP_001906497.1 silverDB:etchr00551 YP_001906498.1 silverDB:etchr00552 YP_001906499.1 silverDB:etchr00553 YP_001906500.1 silverDB:etchr00554 YP_001906501.1 silverDB:etchr10003 YP_001906502.1 silverDB:etchr00555 YP_001906503.1 silverDB:etchr10004 YP_001906504.1 silverDB:etchr00556 YP_001906505.1 silverDB:etchr00557; phage-related protein YP_001906506.1 silverDB:etchr00558; phage-related protein YP_001906507.1 silverDB:etchr00560 YP_001906508.1 silverDB:etchr00561; Levan regulatory protein RlsC, similar to phage-related protein YP_001906509.1 silverDB:etchr10005 YP_001906510.1 silverDB:etchr10007 YP_001906511.1 silverDB:etchr00562 YP_001906512.1 silverDB:etchr00563 YP_001906513.1 silverDB:etchr00564 YP_001906514.1 silverDB:etchr00565 YP_001906515.1 silverDB:etchr00566 YP_001906516.1 silverDB:etchr00567 YP_001906517.1 silverDB:etchr00568 YP_001906518.1 silverDB:etchr00569 YP_001906519.1 silverDB:etchr00570 YP_001906520.1 silverDB:etchr00571 YP_001906521.1 silverDB:etchr00572 YP_001906522.1 silverDB:etchr00573 YP_001906523.1 silverDB:etchr00574 YP_001906524.1 silverDB:etchr00575 YP_001906525.1 silverDB:etchr00576 YP_001906526.1 silverDB:etchr00577 YP_001906527.1 silverDB:etchr00578 YP_001906528.1 silverDB:etchr00579 YP_001906529.1 silverDB:etchr00580 YP_001906530.1 silverDB:etchr00581 YP_001906531.1 silverDB:etchr00582 YP_001906532.1 silverDB:etchr00583 YP_001906533.1 silverDB:etchr00584 YP_001906534.1 silverDB:etchr00585 YP_001906535.1 silverDB:etchr00586 YP_001906536.1 silverDB:etchr00587 YP_001906537.1 silverDB:etchr00588 YP_001906538.1 silverDB:etchr00589 YP_001906539.1 silverDB:etchr10008 YP_001906540.1 silverDB:etchr10009 YP_001906541.1 silverDB:etchr00590 YP_001906542.1 silverDB:etchr00591 YP_001906543.1 silverDB:etchr00592 YP_001906544.1 silverDB:etchr00593 YP_001906545.1 silverDB:etchr00594 YP_001906546.1 silverDB:etchr00595 YP_001906547.1 silverDB:etchr00596 YP_001906548.1 silverDB:etchr00597 YP_001906549.1 silverDB:etchr00598 YP_001906550.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001906551.1 silverDB:etchr00600 YP_001906552.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001906553.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001906554.1 silverDB:etchr00603 YP_001906555.1 silverDB:etchr00604 YP_001906556.1 silverDB:etchr00605 YP_001906557.1 silverDB:etchr00606 YP_001906558.1 silverDB:etchr00607 YP_001906559.1 silverDB:etchr00608 YP_001906560.1 silverDB:etchr00609 YP_001906561.1 silverDB:etchr00610 YP_001906562.1 silverDB:etchr00611 YP_001906563.1 silverDB:etchr00612 YP_001906564.1 silverDB:etchr00613 YP_001906565.1 silverDB:etchr00614 YP_001906566.1 silverDB:etchr00615 YP_001906567.1 silverDB:etchr00616 YP_001906568.1 silverDB:etchr10010 YP_001906569.1 silverDB:etchr00617 YP_001906570.1 silverDB:etchr00618 YP_001906571.1 silverDB:etchr00619 YP_001906572.1 silverDB:etchr00620 YP_001906573.1 silverDB:etchr00621 YP_001906574.1 silverDB:etchr00622 YP_001906575.1 silverDB:etchr00623 YP_001906576.1 silverDB:etchr00624 YP_001906577.1 silverDB:etchr00625 YP_001906578.1 silverDB:etchr00626 YP_001906579.1 silverDB:etchr00627 YP_001906580.1 silverDB:etchr00628 YP_001906581.1 silverDB:etchr00629 YP_001906582.1 silverDB:etchr00630 YP_001906583.1 silverDB:etchr00631 YP_001906584.1 silverDB:etchr00632 YP_001906585.1 silverDB:etchr00633 YP_001906586.1 silverDB:etchr00634 YP_001906587.1 silverDB:etchr00635 YP_001906588.1 silverDB:etchr00636 YP_001906589.1 silverDB:etchr00637 YP_001906590.1 silverDB:etchr00638 YP_001906591.1 silverDB:etchr00639 YP_001906592.1 silverDB:etchr00640 YP_001906593.1 silverDB:etchr00641 YP_001906594.1 silverDB:etchr00642 YP_001906595.1 silverDB:etchr00643 YP_001906596.1 silverDB:etchr00644 YP_001906597.1 silverDB:etchr00645 YP_001906598.1 silverDB:etchr00646 YP_001906599.1 silverDB:etchr00647 YP_001906600.1 silverDB:etchr00648 YP_001906601.1 silverDB:etchr00649 YP_001906602.1 silverDB:etchr00650 YP_001906603.1 silverDB:etchr00651 YP_001906604.1 silverDB:etchr00652 YP_001906605.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001906606.1 silverDB:etchr00654 YP_001906607.1 silverDB:etchr00655 YP_001906608.1 silverDB:etchr00656 YP_001906609.1 silverDB:etchr00657 YP_001906610.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001906611.1 silverDB:etchr00659 YP_001906612.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001906613.1 silverDB:etchr00661 YP_001906614.1 silverDB:etchr00662 YP_001906615.1 silverDB:etchr00663 YP_001906616.1 catalyzes the formation of serine from O-phosphoserine YP_001906617.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001906618.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001906619.1 silverDB:etchr00667 YP_001906620.1 silverDB:etchr00668 YP_001906621.1 silverDB:etchr00669 YP_001906622.1 silverDB:etchr00670 YP_001906623.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001906624.1 silverDB:etchr00672 YP_001906625.1 silverDB:etchr00673 YP_001906626.1 silverDB:etchr00674 YP_001906627.1 silverDB:etchr00675 YP_001906628.1 silverDB:etchr00676 YP_001906629.1 silverDB:etchr00677 YP_001906630.1 silverDB:etchr00678 YP_001906631.1 silverDB:etchr00679 YP_001906632.1 silverDB:etchr00680 YP_001906633.1 catalyzes the hydrolysis of allophanate YP_001906634.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001906635.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001906636.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001906637.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001906638.1 silverDB:etchr00686 YP_001906639.1 silverDB:etchr00687 YP_001906640.1 silverDB:etchr00688 YP_001906641.1 silverDB:etchr00689 YP_001906642.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001906643.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001906644.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001906645.1 silverDB:etchr00693 YP_001906646.1 silverDB:etchr00694 YP_001906647.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001906648.1 silverDB:etchr00696 YP_001906649.1 silverDB:etchr00697 YP_001906650.1 silverDB:etchr00698 YP_001906651.1 silverDB:etchr00699 YP_001906652.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001906653.1 silverDB:etchr00701 YP_001906654.1 silverDB:etchr10012 YP_001906655.1 silverDB:etchr00702 YP_001906656.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001906657.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001906658.1 silverDB:etchr00705 YP_001906659.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001906660.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001906661.1 silverDB:etchr00708 YP_001906662.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001906663.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001906664.1 silverDB:etchr00711 YP_001906665.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001906666.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001906667.1 protein associated with Co2+ and Mg2+ efflux YP_001906668.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001906669.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001906670.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001906671.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001906672.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001906673.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_001906674.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001906675.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001906676.1 silverDB:etchr00723 YP_001906677.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001906678.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001906679.1 silverDB:etchr00726 YP_001906680.1 silverDB:etchr00727 YP_001906681.1 activates sgrS under glucose-phosphate stress conditions YP_001906682.1 silverDB:etchr00729 YP_001906683.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001906684.1 silverDB:etchr00731 YP_001906685.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001906686.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001906687.1 silverDB:etchr00734 YP_001906688.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001906689.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001906690.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001906691.1 silverDB:etchr00738 YP_001906692.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001906693.1 silverDB:etchr00740 YP_001906694.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001906695.1 silverDB:etchr00742 YP_001906696.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001906697.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001906698.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001906699.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001906700.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001906701.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001906702.1 involved in septum formation YP_001906703.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001906704.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001906705.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001906706.1 silverDB:etchr00753 YP_001906707.1 secM translational pause allows for the initiation of secA translation YP_001906708.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001906709.1 silverDB:etchr00756 YP_001906710.1 silverDB:etchr00757 YP_001906711.1 silverDB:etchr00758 YP_001906712.1 silverDB:etchr00759 YP_001906713.1 proton-motive-force-driven choline transporter YP_001906714.1 silverDB:etchr00761 YP_001906715.1 silverDB:etchr00762 YP_001906716.1 silverDB:etchr00763 YP_001906717.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001906718.1 silverDB:etchr00765 YP_001906719.1 silverDB:etchr00766 YP_001906720.1 silverDB:etchr00767 YP_001906721.1 silverDB:etchr00768 YP_001906722.1 silverDB:etchr00769 YP_001906723.1 silverDB:etchr00770 YP_001906724.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_001906725.1 silverDB:etchr00772 YP_001906726.1 silverDB:etchr00773 YP_001906727.1 silverDB:etchr00774 YP_001906728.1 silverDB:etchr00775 YP_001906729.1 silverDB:etchr00776 YP_001906730.1 silverDB:etchr00777 YP_001906731.1 silverDB:etchr00778 YP_001906732.1 silverDB:etchr00779 YP_001906733.1 silverDB:etchr00780 YP_001906734.1 silverDB:etchr00781 YP_001906735.1 silverDB:etchr00782 YP_001906736.1 silverDB:etchr00783 YP_001906737.1 silverDB:etchr00784 YP_001906738.1 silverDB:etchr00785 YP_001906739.1 silverDB:etchr00786 YP_001906740.1 silverDB:etchr00787 YP_001906741.1 silverDB:etchr00788 YP_001906742.1 silverDB:etchr00789 YP_001906743.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001906744.1 silverDB:etchr00791 YP_001906745.1 silverDB:etchr00792 YP_001906746.1 silverDB:etchr00793 YP_001906747.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001906748.1 silverDB:etchr00795 YP_001906749.1 silverDB:etchr00796 YP_001906750.1 silverDB:etchr00797 YP_001906751.1 involved in regulation of beta-lactamase; signaling protein YP_001906752.1 silverDB:etchr00799 YP_001906753.1 silverDB:etchr00800 YP_001906754.1 silverDB:etchr00801 YP_001906755.1 silverDB:etchr00802 YP_001906756.1 silverDB:etchr00803 YP_001906757.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001906758.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001906759.1 silverDB:etchr00806 YP_001906760.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001906761.1 silverDB:etchr00808 YP_001906762.1 silverDB:etchr00809 YP_001906763.1 silverDB:etchr00810 YP_001906764.1 silverDB:etchr00811 YP_001906765.1 silverDB:etchr00812 YP_001906766.1 silverDB:etchr00813 YP_001906767.1 silverDB:etchr00814 YP_001906768.1 silverDB:etchr00815 YP_001906769.1 silverDB:etchr00816 YP_001906770.1 silverDB:etchr00817 YP_001906771.1 silverDB:etchr00818 YP_001906772.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001906773.1 silverDB:etchr00820 YP_001906774.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001906775.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001906776.1 silverDB:etchr00823 YP_001906777.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001906778.1 silverDB:etchr00825 YP_001906779.1 silverDB:etchr00826 YP_001906780.1 silverDB:etchr00827 YP_001906781.1 silverDB:etchr00828 YP_001906782.1 silverDB:etchr00829 YP_001906783.1 silverDB:etchr00830 YP_001906784.1 silverDB:etchr00831 YP_001906785.1 silverDB:etchr00832 YP_001906786.1 silverDB:etchr00833 YP_001906787.1 silverDB:etchr00834 YP_001906788.1 silverDB:etchr00835 YP_001906789.1 silverDB:etchr00836 YP_001906790.1 silverDB:etchr00837 YP_001906791.1 silverDB:etchr00838 YP_001906792.1 silverDB:etchr00839 YP_001906793.1 silverDB:etchr00840 YP_001906794.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_001906795.1 silverDB:etchr00842 YP_001906796.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_001906797.1 silverDB:etchr00844 YP_001906798.1 silverDB:etchr00845 YP_001906799.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001906800.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001906801.1 silverDB:etchr00848 YP_001906802.1 silverDB:etchr00849 YP_001906803.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001906804.1 silverDB:etchr00851 YP_001906805.1 silverDB:etchr00852 YP_001906806.1 silverDB:etchr00853 YP_001906807.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001906808.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001906809.1 silverDB:etchr00856 YP_001906810.1 silverDB:etchr00857 YP_001906811.1 silverDB:etchr00858 YP_001906812.1 silverDB:etchr00859 YP_001906813.1 silverDB:etchr00860 YP_001906814.1 silverDB:etchr00861 YP_001906815.1 silverDB:etchr00862 YP_001906816.1 silverDB:etchr00863 YP_001906817.1 silverDB:etchr00864 YP_001906818.1 silverDB:etchr00865 YP_001906819.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001906820.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001906821.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001906822.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001906823.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001906824.1 silverDB:etchr00871 YP_001906825.1 silverDB:etchr00872 YP_001906826.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001906827.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001906828.1 protease Do; required at high temperature; degrades damaged proteins YP_001906829.1 silverDB:etchr00876 YP_001906830.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001906831.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001906832.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001906833.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001906834.1 silverDB:etchr00881 YP_001906835.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001906836.1 Catalyzes the phosphorylation of UMP to UDP YP_001906837.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001906838.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001906839.1 silverDB:etchr00886 YP_001906840.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001906841.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001906842.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001906843.1 silverDB:etchr00890 YP_001906844.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001906845.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001906846.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001906847.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001906848.1 silverDB:etchr00895 YP_001906849.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001906850.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001906851.1 silverDB:etchr00898 YP_001906852.1 silverDB:etchr00899 YP_001906853.1 silverDB:etchr00900 YP_001906854.1 silverDB:etchr00901 YP_001906855.1 silverDB:etchr00902 YP_001906856.1 silverDB:etchr00903 YP_001906857.1 silverDB:etchr00904 YP_001906858.1 silverDB:etchr00905 YP_001906859.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001906860.1 silverDB:etchr00907 YP_001906861.1 silverDB:etchr00908 YP_001906862.1 silverDB:etchr00909 YP_001906863.1 part of the MetNIQ methionine uptake system YP_001906864.1 part of the metNIQ transport system for methionine YP_001906865.1 silverDB:etchr00912 YP_001906866.1 silverDB:etchr00913 YP_001906867.1 silverDB:etchr00914 YP_001906868.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001906869.1 silverDB:etchr00916 YP_001906870.1 silverDB:etchr00917 YP_001906871.1 silverDB:etchr00918 YP_001906872.1 silverDB:etchr00919 YP_001906873.1 silverDB:etchr00920 YP_001906874.1 silverDB:etchr00921 YP_001906875.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001906876.1 silverDB:etchr00923 YP_001906877.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001906878.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001906879.1 silverDB:etchr00926 YP_001906880.1 silverDB:etchr00927 YP_001906881.1 silverDB:etchr00928 YP_001906882.1 silverDB:etchr00929 YP_001906883.1 silverDB:etchr00930 YP_001906884.1 silverDB:etchr00931 YP_001906885.1 silverDB:etchr00932 YP_001906886.1 silverDB:etchr00933 YP_001906887.1 silverDB:etchr00934 YP_001906888.1 silverDB:etchr00935 YP_001906889.1 silverDB:etchr00936 YP_001906890.1 silverDB:etchr00937 YP_001906891.1 silverDB:etchr00938 YP_001906892.1 silverDB:etchr00939 YP_001906893.1 silverDB:etchr00940 YP_001906894.1 silverDB:etchr00941 YP_001906895.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001906896.1 silverDB:etchr00943 YP_001906897.1 silverDB:etchr00944 YP_001906898.1 silverDB:etchr00945 YP_001906899.1 silverDB:etchr00946 YP_001906900.1 silverDB:etchr00947 YP_001906901.1 silverDB:etchr00948 YP_001906902.1 silverDB:etchr00949 YP_001906903.1 silverDB:etchr00950 YP_001906904.1 silverDB:etchr00951 YP_001906905.1 silverDB:etchr00953 YP_001906906.1 silverDB:etchr00954 YP_001906907.1 silverDB:etchr00955 YP_001906908.1 silverDB:etchr00956 YP_001906909.1 silverDB:etchr00957 YP_001906910.1 silverDB:etchr00958 YP_001906911.1 silverDB:etchr00959 YP_001906912.1 silverDB:etchr00960 YP_001906913.1 silverDB:etchr00961 YP_001906914.1 silverDB:etchr00962 YP_001906915.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001906916.1 silverDB:etchr00964 YP_001906917.1 silverDB:etchr00965 YP_001906918.1 silverDB:etchr00966 YP_001906919.1 silverDB:etchr00967 YP_001906920.1 silverDB:etchr00968 YP_001906921.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001906922.1 silverDB:etchr00970 YP_001906923.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001906924.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001906925.1 silverDB:etchr00973 YP_001906926.1 silverDB:etchr00974 YP_001906927.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001906928.1 silverDB:etchr00976 YP_001906929.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001906930.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001906931.1 silverDB:etchr00979 YP_001906932.1 silverDB:etchr00980 YP_001906933.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001906934.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001906935.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001906936.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001906937.1 silverDB:etchr00985 YP_001906938.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001906939.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001906940.1 silverDB:etchr00988 YP_001906941.1 silverDB:etchr00989 YP_001906942.1 silverDB:etchr00990 YP_001906943.1 silverDB:etchr00991 YP_001906944.1 silverDB:etchr00992 YP_001906945.1 silverDB:etchr00993 YP_001906946.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001906947.1 silverDB:etchr00995 YP_001906948.1 silverDB:etchr00996 YP_001906949.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001906950.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001906951.1 silverDB:etchr00999 YP_001906952.1 silverDB:etchr01000 YP_001906953.1 silverDB:etchr01001 YP_001906954.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001906955.1 silverDB:etchr01003 YP_001906956.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001906957.1 silverDB:etchr01005 YP_001906958.1 silverDB:etchr01006 YP_001906959.1 silverDB:etchr01007 YP_001906960.1 silverDB:etchr01008 YP_001906961.1 silverDB:etchr01009 YP_001906962.1 regulates the expression of the iscRSUA operon YP_001906963.1 silverDB:etchr01011 YP_001906964.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001906965.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001906966.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_001906967.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001906968.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001906969.1 silverDB:etchr01017 YP_001906970.1 silverDB:etchr01018 YP_001906971.1 silverDB:etchr01019 YP_001906972.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001906973.1 silverDB:etchr01021 YP_001906974.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001906975.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001906976.1 silverDB:etchr01024 YP_001906977.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001906978.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001906979.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001906980.1 silverDB:etchr01028 YP_001906981.1 silverDB:etchr01029 YP_001906982.1 silverDB:etchr01030 YP_001906983.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001906984.1 silverDB:etchr01032 YP_001906985.1 silverDB:etchr01033 YP_001906986.1 silverDB:etchr01034 YP_001906987.1 silverDB:etchr01035 YP_001906988.1 silverDB:etchr01036 YP_001906989.1 silverDB:etchr01037 YP_001906990.1 silverDB:etchr01038 YP_001906991.1 silverDB:etchr01039 YP_001906992.1 with TehA confers resistance to tellurite YP_001906993.1 silverDB:etchr01041 YP_001906994.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001906995.1 silverDB:etchr01043 YP_001906996.1 silverDB:etchr01044 YP_001906997.1 silverDB:etchr01045 YP_001906998.1 silverDB:etchr01046 YP_001906999.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001907000.1 silverDB:etchr01048 YP_001907001.1 silverDB:etchr01049 YP_001907002.1 silverDB:etchr01050 YP_001907003.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001907004.1 silverDB:etchr01052 YP_001907005.1 silverDB:etchr01053 YP_001907006.1 silverDB:etchr01054 YP_001907007.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001907008.1 negative transcriptional regulator of the gcvTHP operon YP_001907009.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001907010.1 silverDB:etchr01058 YP_001907011.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001907012.1 silverDB:etchr01060 YP_001907013.1 silverDB:etchr01061 YP_001907014.1 silverDB:etchr01062 YP_001907015.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001907016.1 silverDB:etchr01064 YP_001907017.1 silverDB:etchr01065 YP_001907018.1 silverDB:etchr01066 YP_001907019.1 silverDB:etchr01067 YP_001907020.1 silverDB:etchr01068 YP_001907021.1 silverDB:etchr01069 YP_001907022.1 silverDB:etchr01070 YP_001907023.1 silverDB:etchr01071 YP_001907024.1 silverDB:etchr01072 YP_001907025.1 silverDB:etchr01073 YP_001907026.1 silverDB:etchr01074 YP_001907027.1 silverDB:etchr01075 YP_001907028.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001907029.1 silverDB:etchr01077 YP_001907030.1 silverDB:etchr01078 YP_001907031.1 silverDB:etchr01079 YP_001907032.1 silverDB:etchr01080 YP_001907033.1 silverDB:etchr01081 YP_001907034.1 silverDB:etchr01082 YP_001907035.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001907036.1 silverDB:etchr01084 YP_001907037.1 silverDB:etchr01085 YP_001907038.1 silverDB:etchr01086 YP_001907039.1 silverDB:etchr01087 YP_001907040.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001907041.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001907042.1 silverDB:etchr01090 YP_001907043.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001907044.1 silverDB:etchr01092 YP_001907045.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001907046.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001907047.1 silverDB:etchr01095 YP_001907048.1 silverDB:etchr01096 YP_001907049.1 silverDB:etchr01097 YP_001907050.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001907051.1 silverDB:etchr01099 YP_001907052.1 silverDB:etchr01100 YP_001907053.1 silverDB:etchr01101 YP_001907054.1 silverDB:etchr01102 YP_001907055.1 silverDB:etchr01103 YP_001907056.1 silverDB:etchr01104 YP_001907057.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001907058.1 silverDB:etchr01106 YP_001907059.1 silverDB:etchr01107 YP_001907060.1 silverDB:etchr01108 YP_001907061.1 silverDB:etchr01109 YP_001907062.1 silverDB:etchr01110 YP_001907063.1 silverDB:etchr01111 YP_001907064.1 silverDB:etchr01112 YP_001907065.1 silverDB:etchr01113 YP_001907066.1 silverDB:etchr01114 YP_001907067.1 silverDB:etchr01115 YP_001907068.1 silverDB:etchr01116 YP_001907069.1 silverDB:etchr01117 YP_001907070.1 silverDB:etchr01118 YP_001907071.1 silverDB:etchr01119 YP_001907072.1 silverDB:etchr01123 YP_001907073.1 silverDB:etchr01124 YP_001907074.1 silverDB:etchr01125 YP_001907075.1 silverDB:etchr01126 YP_001907076.1 silverDB:etchr01127 YP_001907077.1 silverDB:etchr01128 YP_001907078.1 silverDB:etchr01129 YP_001907079.1 silverDB:etchr01130 YP_001907080.1 silverDB:etchr01131 YP_001907081.1 silverDB:etchr01132 YP_001907082.1 silverDB:etchr01133 YP_001907083.1 silverDB:etchr01134 YP_001907084.1 silverDB:etchr01135 YP_001907085.1 silverDB:etchr01136 YP_001907086.1 silverDB:etchr01137 YP_001907087.1 silverDB:etchr01138 YP_001907088.1 silverDB:etchr01139 YP_001907089.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001907090.1 silverDB:etchr01141 YP_001907091.1 silverDB:etchr01142 YP_001907092.1 silverDB:etchr01143 YP_001907093.1 silverDB:etchr01144 YP_001907094.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001907095.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001907096.1 silverDB:etchr01147 YP_001907097.1 silverDB:etchr01148 YP_001907098.1 silverDB:etchr01149 YP_001907099.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001907100.1 silverDB:etchr01151 YP_001907101.1 silverDB:etchr01152 YP_001907102.1 silverDB:etchr01153 YP_001907103.1 silverDB:etchr01154 YP_001907104.1 silverDB:etchr01155 YP_001907105.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001907106.1 silverDB:etchr01157 YP_001907107.1 silverDB:etchr01158 YP_001907108.1 silverDB:etchr01159 YP_001907109.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001907110.1 silverDB:etchr01161 YP_001907111.1 silverDB:etchr01162 YP_001907112.1 silverDB:etchr01163 YP_001907113.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001907114.1 silverDB:etchr01165 YP_001907115.1 silverDB:etchr01166 YP_001907116.1 silverDB:etchr01167 YP_001907117.1 membrane protein required for colicin V production YP_001907118.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001907119.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001907120.1 silverDB:etchr01171 YP_001907121.1 silverDB:etchr01172 YP_001907122.1 silverDB:etchr01173 YP_001907123.1 silverDB:etchr01174 YP_001907124.1 silverDB:etchr01175 YP_001907125.1 silverDB:etchr01176 YP_001907126.1 silverDB:etchr01177 YP_001907127.1 silverDB:etchr01178 YP_001907128.1 silverDB:etchr01179 YP_001907129.1 silverDB:etchr01180 YP_001907130.1 silverDB:etchr01181 YP_001907131.1 silverDB:etchr01182 YP_001907132.1 silverDB:etchr01183 YP_001907133.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001907134.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001907135.1 silverDB:etchr01186 YP_001907136.1 silverDB:etchr01187 YP_001907137.1 silverDB:etchr01188 YP_001907138.1 silverDB:etchr01189 YP_001907139.1 silverDB:etchr01190 YP_001907140.1 silverDB:etchr01191 YP_001907141.1 silverDB:etchr01192 YP_001907142.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001907143.1 silverDB:etchr01194 YP_001907144.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907145.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001907146.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001907147.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907148.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001907149.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907150.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907151.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907152.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907153.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907154.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001907155.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907156.1 Catalyzes the transfer of electrons from NADH to quinone YP_001907157.1 silverDB:etchr01208 YP_001907158.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001907159.1 silverDB:etchr01210 YP_001907160.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001907161.1 silverDB:etchr01212 YP_001907162.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001907163.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001907164.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001907165.1 Involved in ubiquinone biosynthesis YP_001907166.1 negatively supercoils closed circular double-stranded DNA YP_001907167.1 silverDB:etchr01218 YP_001907168.1 silverDB:etchr01219 YP_001907169.1 silverDB:etchr01220 YP_001907170.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001907171.1 silverDB:etchr01222 YP_001907172.1 silverDB:etchr01223 YP_001907173.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001907174.1 silverDB:etchr01225 YP_001907175.1 efflux pump for the antibacterial peptide microcin J25 YP_001907176.1 silverDB:etchr01227 YP_001907177.1 silverDB:etchr01228 YP_001907178.1 silverDB:etchr01229 YP_001907179.1 silverDB:etchr01230 YP_001907180.1 silverDB:etchr01231 YP_001907181.1 silverDB:etchr01232 YP_001907182.1 silverDB:etchr01233 YP_001907183.1 silverDB:etchr01234 YP_001907184.1 silverDB:etchr01235 YP_001907185.1 silverDB:etchr01236 YP_001907186.1 silverDB:etchr01237 YP_001907187.1 silverDB:etchr01238 YP_001907188.1 silverDB:etchr01239 YP_001907189.1 silverDB:etchr01240 YP_001907190.1 silverDB:etchr01241 YP_001907191.1 silverDB:etchr01242 YP_001907192.1 silverDB:etchr01243 YP_001907193.1 silverDB:etchr01244 YP_001907194.1 silverDB:etchr01246 YP_001907195.1 silverDB:etchr01247 YP_001907196.1 silverDB:etchr01248 YP_001907197.1 silverDB:etchr01249 YP_001907198.1 silverDB:etchr01250 YP_001907199.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001907200.1 silverDB:etchr01251 YP_001907201.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001907202.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001907203.1 silverDB:etchr01254 YP_001907204.1 silverDB:etchr01255 YP_001907205.1 silverDB:etchr01256 YP_001907206.1 silverDB:etchr01257 YP_001907207.1 silverDB:etchr01258 YP_001907208.1 silverDB:etchr01259 YP_001907209.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001907210.1 silverDB:etchr01261 YP_001907211.1 silverDB:etchr01262 YP_001907212.1 silverDB:etchr01263 YP_001907213.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001907214.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001907215.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001907216.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001907217.1 silverDB:etchr01268 YP_001907218.1 silverDB:etchr01269 YP_001907219.1 silverDB:etchr01270 YP_001907220.1 silverDB:etchr01271 YP_001907221.1 silverDB:etchr01272 YP_001907222.1 silverDB:etchr01273 YP_001907223.1 silverDB:etchr01274 YP_001907224.1 silverDB:etchr01275 YP_001907225.1 silverDB:etchr01276 YP_001907226.1 silverDB:etchr01277 YP_001907227.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001907228.1 silverDB:etchr01279 YP_001907229.1 negative regulator of the mglBAC operon for galactose utilization YP_001907230.1 silverDB:etchr01281 YP_001907231.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001907232.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001907233.1 silverDB:etchr01284 YP_001907234.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001907235.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001907236.1 silverDB:etchr01287 YP_001907237.1 silverDB:etchr01288 YP_001907238.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001907239.1 silverDB:etchr01290 YP_001907240.1 silverDB:etchr01291 YP_001907241.1 silverDB:etchr01292 YP_001907242.1 silverDB:etchr01293 YP_001907243.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001907244.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001907245.1 silverDB:etchr01296 YP_001907246.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001907247.1 silverDB:etchr01298 YP_001907248.1 silverDB:etchr01299 YP_001907249.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001907250.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001907251.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001907252.1 silverDB:etchr01303 YP_001907253.1 silverDB:etchr01304 YP_001907254.1 silverDB:etchr01305 YP_001907255.1 silverDB:etchr01306 YP_001907256.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001907257.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001907258.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001907259.1 silverDB:etchr01310 YP_001907260.1 silverDB:etchr01311 YP_001907261.1 silverDB:etchr01312 YP_001907262.1 silverDB:etchr01313 YP_001907263.1 silverDB:etchr01314 YP_001907264.1 silverDB:etchr01315 YP_001907265.1 silverDB:etchr01316 YP_001907266.1 silverDB:etchr01317 YP_001907267.1 silverDB:etchr01318 YP_001907268.1 silverDB:etchr01319 YP_001907269.1 silverDB:etchr01320 YP_001907270.1 silverDB:etchr01321 YP_001907271.1 silverDB:etchr01322 YP_001907272.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001907273.1 silverDB:etchr01324 YP_001907274.1 silverDB:etchr01325 YP_001907275.1 silverDB:etchr01326 YP_001907276.1 silverDB:etchr01327 YP_001907277.1 silverDB:etchr01328 YP_001907278.1 silverDB:etchr01329 YP_001907279.1 silverDB:etchr01330 YP_001907280.1 silverDB:etchr01331 YP_001907281.1 silverDB:etchr01332 YP_001907282.1 silverDB:etchr01333 YP_001907283.1 silverDB:etchr01334 YP_001907284.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001907285.1 silverDB:etchr01336 YP_001907286.1 silverDB:etchr01337 YP_001907287.1 silverDB:etchr01338 YP_001907288.1 silverDB:etchr01339 YP_001907289.1 silverDB:etchr01340 YP_001907290.1 silverDB:etchr01341 YP_001907291.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001907292.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001907293.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001907294.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001907295.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001907296.1 silverDB:etchr01347 YP_001907297.1 silverDB:etchr01348 YP_001907298.1 silverDB:etchr01349 YP_001907299.1 silverDB:etchr01350 YP_001907300.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001907301.1 silverDB:etchr01352 YP_001907302.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001907303.1 silverDB:etchr01354 YP_001907304.1 silverDB:etchr01355 YP_001907305.1 silverDB:etchr01356 YP_001907306.1 silverDB:etchr01357 YP_001907307.1 silverDB:etchr01358 YP_001907308.1 silverDB:etchr01359 YP_001907309.1 silverDB:etchr01360 YP_001907310.1 silverDB:etchr01361 YP_001907311.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001907312.1 silverDB:etchr01363 YP_001907313.1 silverDB:etchr01364 YP_001907314.1 silverDB:etchr01365 YP_001907315.1 silverDB:etchr01366 YP_001907316.1 silverDB:etchr01367 YP_001907317.1 silverDB:etchr01368 YP_001907318.1 silverDB:etchr01369 YP_001907319.1 silverDB:etchr01370 YP_001907320.1 transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001907321.1 LysR family transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_001907322.1 silverDB:etchr01373 YP_001907323.1 silverDB:etchr01374 YP_001907324.1 silverDB:etchr01375 YP_001907325.1 silverDB:etchr01376 YP_001907326.1 silverDB:etchr01377 YP_001907327.1 silverDB:etchr01378 YP_001907328.1 silverDB:etchr01379 YP_001907329.1 silverDB:etchr01380 YP_001907330.1 silverDB:etchr01381 YP_001907331.1 silverDB:etchr01382 YP_001907332.1 silverDB:etchr01383 YP_001907333.1 silverDB:etchr01384 YP_001907334.1 silverDB:etchr01385 YP_001907335.1 silverDB:etchr01386 YP_001907336.1 silverDB:etchr01387 YP_001907337.1 silverDB:etchr01388 YP_001907338.1 silverDB:etchr01389 YP_001907339.1 silverDB:etchr01390 YP_001907340.1 silverDB:etchr01391 YP_001907341.1 silverDB:etchr01392 YP_001907342.1 silverDB:etchr01393 YP_001907343.1 silverDB:etchr01394 YP_001907344.1 silverDB:etchr01395 YP_001907345.1 silverDB:etchr01396 YP_001907346.1 silverDB:etchr01397 YP_001907347.1 silverDB:etchr01398 YP_001907348.1 silverDB:etchr01399 YP_001907349.1 silverDB:etchr01400 YP_001907350.1 silverDB:etchr01401 YP_001907351.1 silverDB:etchr01402 YP_001907352.1 silverDB:etchr01403 YP_001907353.1 silverDB:etchr01404 YP_001907354.1 silverDB:etchr01405 YP_001907355.1 silverDB:etchr01406 YP_001907356.1 silverDB:etchr01407 YP_001907357.1 silverDB:etchr01408 YP_001907358.1 silverDB:etchr01409 YP_001907359.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001907360.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001907361.1 silverDB:etchr01412 YP_001907362.1 involved in flagellin assembly YP_001907363.1 silverDB:etchr01414 YP_001907364.1 silverDB:etchr01415 YP_001907365.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001907366.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001907367.1 catalyzes the formation of pyruvate from D-cysteine YP_001907368.1 silverDB:etchr01419 YP_001907369.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001907370.1 silverDB:etchr01421 YP_001907371.1 silverDB:etchr01422 YP_001907372.1 silverDB:etchr01423 YP_001907373.1 silverDB:etchr01424 YP_001907374.1 silverDB:etchr01425 YP_001907375.1 silverDB:etchr01426 YP_001907376.1 silverDB:etchr01427 YP_001907377.1 silverDB:etchr01428 YP_001907378.1 silverDB:etchr01429 YP_001907379.1 silverDB:etchr01430 YP_001907380.1 silverDB:etchr01431 YP_001907381.1 silverDB:etchr01432 YP_001907382.1 silverDB:etchr01433 YP_001907383.1 silverDB:etchr01434 YP_001907384.1 silverDB:etchr01435 YP_001907385.1 silverDB:etchr01436 YP_001907386.1 silverDB:etchr01437 YP_001907387.1 silverDB:etchr01438 YP_001907388.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001907389.1 silverDB:etchr01440 YP_001907390.1 silverDB:etchr01441 YP_001907391.1 silverDB:etchr01442 YP_001907392.1 silverDB:etchr01443 YP_001907393.1 silverDB:etchr01444 YP_001907394.1 silverDB:etchr01445 YP_001907395.1 silverDB:etchr01446 YP_001907396.1 silverDB:etchr01447 YP_001907397.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001907398.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001907399.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001907400.1 silverDB:etchr01451 YP_001907401.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001907402.1 silverDB:etchr01453 YP_001907403.1 silverDB:etchr01454 YP_001907404.1 silverDB:etchr01455 YP_001907405.1 silverDB:etchr01456 YP_001907406.1 silverDB:etchr01457 YP_001907407.1 methylates the MCP YP_001907408.1 silverDB:etchr01459 YP_001907409.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001907410.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001907411.1 silverDB:etchr01462 YP_001907412.1 membrane protein involved in the flagellar export apparatus YP_001907413.1 silverDB:etchr01464 YP_001907414.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001907415.1 silverDB:etchr01466 YP_001907416.1 silverDB:etchr01467 YP_001907417.1 silverDB:etchr01468 YP_001907418.1 silverDB:etchr01469 YP_001907419.1 silverDB:etchr01470 YP_001907420.1 silverDB:etchr01471 YP_001907421.1 silverDB:etchr01472 YP_001907422.1 silverDB:etchr01473 YP_001907423.1 silverDB:etchr01474 YP_001907424.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001907425.1 silverDB:etchr01476 YP_001907426.1 silverDB:etchr01477 YP_001907427.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001907428.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001907429.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001907430.1 involved in transport of zinc(II) with ZnuA and C YP_001907431.1 involved in transport of zinc(II) with ZnuA and C YP_001907432.1 involved in transport of zinc(II) with ZnuA and C YP_001907433.1 silverDB:etchr01484 YP_001907434.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001907435.1 silverDB:etchr01486 YP_001907436.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001907437.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001907438.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001907439.1 silverDB:etchr01490 YP_001907440.1 silverDB:etchr01491 YP_001907441.1 silverDB:etchr01492 YP_001907442.1 silverDB:etchr01493 YP_001907443.1 3'-5' exonuclease activity on single or double-strand DNA YP_001907444.1 silverDB:etchr01495 YP_001907445.1 silverDB:etchr01496 YP_001907446.1 silverDB:etchr01497 YP_001907447.1 silverDB:etchr01498 YP_001907448.1 silverDB:etchr01499 YP_001907449.1 silverDB:etchr01500 YP_001907450.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001907451.1 silverDB:etchr01502 YP_001907452.1 silverDB:etchr01503 YP_001907453.1 silverDB:etchr01504 YP_001907454.1 affects solute and DNA transport through an unknown mechanism YP_001907455.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001907456.1 metalloprotease YP_001907457.1 silverDB:etchr01508 YP_001907458.1 silverDB:etchr01509 YP_001907459.1 silverDB:etchr01510 YP_001907460.1 silverDB:etchr01511 YP_001907461.1 silverDB:etchr01512 YP_001907462.1 silverDB:etchr01513 YP_001907463.1 silverDB:etchr01514 YP_001907464.1 silverDB:etchr01515 YP_001907465.1 silverDB:etchr01516 YP_001907466.1 silverDB:etchr01517 YP_001907467.1 silverDB:etchr01518 YP_001907468.1 silverDB:etchr01519 YP_001907469.1 silverDB:etchr01520 YP_001907470.1 silverDB:etchr01521 YP_001907471.1 silverDB:etchr01522 YP_001907472.1 silverDB:etchr01523 YP_001907473.1 silverDB:etchr01524 YP_001907474.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001907475.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001907476.1 blocks the formation of polar Z-ring septums YP_001907477.1 silverDB:etchr01528 YP_001907478.1 silverDB:etchr01529 YP_001907479.1 silverDB:etchr01530 YP_001907480.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001907481.1 multifunctional regulator of fatty acid metabolism YP_001907482.1 silverDB:etchr01533 YP_001907483.1 catalyzes the oxidative deamination of D-amino acids YP_001907484.1 silverDB:etchr01535 YP_001907485.1 silverDB:etchr01536 YP_001907486.1 silverDB:etchr01537 YP_001907487.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001907488.1 silverDB:etchr01539 YP_001907489.1 silverDB:etchr01540 YP_001907490.1 silverDB:etchr01541 YP_001907491.1 silverDB:etchr01542 YP_001907492.1 silverDB:etchr01543 YP_001907493.1 silverDB:etchr01544 YP_001907494.1 silverDB:etchr01545 YP_001907495.1 silverDB:etchr01546 YP_001907496.1 silverDB:etchr01547 YP_001907497.1 silverDB:etchr01548 YP_001907498.1 silverDB:etchr01549 YP_001907499.1 silverDB:etchr01550 YP_001907500.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001907501.1 silverDB:etchr01552 YP_001907502.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001907503.1 converts asparagine to aspartate and ammonia YP_001907504.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001907505.1 silverDB:etchr01556 YP_001907506.1 decatenates replicating daughter chromosomes YP_001907507.1 silverDB:etchr01558 YP_001907508.1 silverDB:etchr01559 YP_001907509.1 silverDB:etchr01560 YP_001907510.1 silverDB:etchr01561 YP_001907511.1 silverDB:etchr01562 YP_001907512.1 silverDB:etchr01563 YP_001907513.1 silverDB:etchr01564 YP_001907514.1 silverDB:etchr01565 YP_001907515.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001907516.1 silverDB:etchr01567 YP_001907517.1 silverDB:etchr01568 YP_001907518.1 silverDB:etchr01569 YP_001907519.1 silverDB:etchr01570 YP_001907520.1 silverDB:etchr01571 YP_001907521.1 silverDB:etchr01572 YP_001907522.1 silverDB:etchr01573 YP_001907523.1 silverDB:etchr01574 YP_001907524.1 silverDB:etchr01575 YP_001907525.1 silverDB:etchr01576 YP_001907526.1 silverDB:etchr01577 YP_001907527.1 silverDB:etchr01578 YP_001907528.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001907529.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001907530.1 silverDB:etchr01581 YP_001907531.1 silverDB:etchr01582 YP_001907532.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001907533.1 silverDB:etchr01584 YP_001907534.1 Involved in cell division; probably involved in intracellular septation YP_001907535.1 silverDB:etchr01586 YP_001907536.1 silverDB:etchr01587 YP_001907537.1 silverDB:etchr01588 YP_001907538.1 silverDB:etchr01589 YP_001907539.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001907540.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001907541.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001907542.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001907543.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001907544.1 silverDB:etchr01595 YP_001907545.1 silverDB:etchr01596 YP_001907546.1 silverDB:etchr01597 YP_001907547.1 silverDB:etchr01598 YP_001907548.1 silverDB:etchr01599 YP_001907549.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001907550.1 silverDB:etchr01601 YP_001907551.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001907552.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001907553.1 LysR family transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001907554.1 silverDB:etchr01605 YP_001907555.1 Catalyzes the conversion of citrate to isocitrate YP_001907556.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001907557.1 silverDB:etchr01608 YP_001907558.1 silverDB:etchr01609 YP_001907559.1 silverDB:etchr01610 YP_001907560.1 silverDB:etchr01611 YP_001907561.1 involved in start site selection during the initiation of translation YP_001907562.1 silverDB:etchr01613 YP_001907563.1 silverDB:etchr01614 YP_001907564.1 silverDB:etchr01615 YP_001907565.1 silverDB:etchr01616 YP_001907566.1 silverDB:etchr01617 YP_001907567.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001907568.1 silverDB:etchr01619 YP_001907569.1 silverDB:etchr01620 YP_001907570.1 silverDB:etchr01621 YP_001907571.1 silverDB:etchr01622 YP_001907572.1 silverDB:etchr01623 YP_001907573.1 silverDB:etchr01624 YP_001907574.1 silverDB:etchr01625 YP_001907575.1 silverDB:etchr01626 YP_001907576.1 silverDB:etchr01627 YP_001907577.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001907578.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001907579.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001907580.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001907581.1 silverDB:etchr01632 YP_001907582.1 silverDB:etchr01633 YP_001907583.1 silverDB:etchr01634 YP_001907584.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001907585.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001907586.1 silverDB:etchr01637 YP_001907587.1 silverDB:etchr01638 YP_001907588.1 silverDB:etchr01639 YP_001907589.1 silverDB:etchr01640 YP_001907590.1 member of the periplasmic pilus chaperone family of proteins YP_001907591.1 silverDB:etchr01642 YP_001907592.1 silverDB:etchr01643 YP_001907593.1 silverDB:etchr01644 YP_001907594.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001907595.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001907596.1 silverDB:etchr01647 YP_001907597.1 silverDB:etchr01648 YP_001907598.1 silverDB:etchr01649 YP_001907599.1 silverDB:etchr01650 YP_001907600.1 silverDB:etchr01651 YP_001907601.1 silverDB:etchr01652 YP_001907602.1 silverDB:etchr01653 YP_001907603.1 silverDB:etchr01654 YP_001907604.1 silverDB:etchr01655 YP_001907605.1 silverDB:etchr01656 YP_001907606.1 silverDB:etchr01657 YP_001907607.1 silverDB:etchr01658 YP_001907608.1 silverDB:etchr01659 YP_001907609.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001907610.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001907611.1 silverDB:etchr01662 YP_001907612.1 silverDB:etchr01663 YP_001907613.1 required for growth and survival under moderately acid conditions YP_001907614.1 silverDB:etchr01665 YP_001907615.1 silverDB:etchr01666 YP_001907616.1 silverDB:etchr01667 YP_001907617.1 response regulator in two-component regulatory system with RstB YP_001907618.1 silverDB:etchr01669 YP_001907619.1 silverDB:etchr01670 YP_001907620.1 silverDB:etchr01671 YP_001907621.1 silverDB:etchr01672 YP_001907622.1 silverDB:etchr01673 YP_001907623.1 silverDB:etchr01674 YP_001907624.1 with UspC and UspD is involved in resistance to UV irradiation YP_001907625.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001907626.1 silverDB:etchr01677 YP_001907627.1 silverDB:etchr01678 YP_001907628.1 silverDB:etchr01679 YP_001907629.1 silverDB:etchr01680 YP_001907630.1 silverDB:etchr01681 YP_001907631.1 silverDB:etchr01682 YP_001907632.1 silverDB:etchr01683 YP_001907633.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001907634.1 silverDB:etchr01685 YP_001907635.1 silverDB:etchr01686 YP_001907636.1 silverDB:etchr01687 YP_001907637.1 catalyzes the formation of glutamate from glutamine YP_001907638.1 silverDB:etchr01689 YP_001907639.1 silverDB:etchr01691 YP_001907640.1 silverDB:etchr01692 YP_001907641.1 silverDB:etchr01693 YP_001907642.1 silverDB:etchr01694 YP_001907643.1 silverDB:etchr01695 YP_001907644.1 silverDB:etchr01696 YP_001907645.1 silverDB:etchr01697 YP_001907646.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001907647.1 silverDB:etchr01699 YP_001907648.1 silverDB:etchr01700 YP_001907649.1 silverDB:etchr01701 YP_001907650.1 silverDB:etchr10018 YP_001907651.1 silverDB:etchr01702 YP_001907652.1 silverDB:etchr01706 YP_001907653.1 silverDB:etchr01707 YP_001907654.1 silverDB:etchr01708 YP_001907655.1 silverDB:etchr01709 YP_001907656.1 silverDB:etchr01710 YP_001907657.1 silverDB:etchr01711 YP_001907658.1 silverDB:etchr01712 YP_001907659.1 silverDB:etchr01713 YP_001907660.1 silverDB:etchr01714 YP_001907661.1 silverDB:etchr01715 YP_001907662.1 silverDB:etchr01716 YP_001907663.1 silverDB:etchr01717 YP_001907664.1 silverDB:etchr01718 YP_001907665.1 silverDB:etchr01719 YP_001907666.1 silverDB:etchr01720 YP_001907667.1 silverDB:etchr01721 YP_001907668.1 silverDB:etchr01722 YP_001907669.1 silverDB:etchr01723 YP_001907670.1 silverDB:etchr01724 YP_001907671.1 silverDB:etchr01725 YP_001907672.1 silverDB:etchr01726 YP_001907673.1 silverDB:etchr01727 YP_001907674.1 silverDB:etchr01728 YP_001907675.1 silverDB:etchr01729 YP_001907676.1 silverDB:etchr01730 YP_001907677.1 silverDB:etchr01731 YP_001907678.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001907679.1 silverDB:etchr01733 YP_001907680.1 silverDB:etchr01734 YP_001907681.1 silverDB:etchr01735 YP_001907682.1 silverDB:etchr01736 YP_001907683.1 silverDB:etchr01737 YP_001907684.1 silverDB:etchr01738 YP_001907685.1 silverDB:etchr01739 YP_001907686.1 silverDB:etchr01740 YP_001907687.1 silverDB:etchr01741 YP_001907688.1 silverDB:etchr01742 YP_001907689.1 silverDB:etchr01743 YP_001907690.1 silverDB:etchr01744 YP_001907691.1 silverDB:etchr01745 YP_001907692.1 silverDB:etchr01746 YP_001907693.1 silverDB:etchr01747 YP_001907694.1 silverDB:etchr01748 YP_001907695.1 silverDB:etchr01749 YP_001907696.1 silverDB:etchr01750 YP_001907697.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001907698.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001907699.1 silverDB:etchr01753 YP_001907700.1 silverDB:etchr01754 YP_001907701.1 silverDB:etchr01755 YP_001907702.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001907703.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001907704.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001907705.1 silverDB:etchr01759 YP_001907706.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001907707.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001907708.1 silverDB:etchr01762 YP_001907709.1 silverDB:etchr01763 YP_001907710.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001907711.1 silverDB:etchr01765 YP_001907712.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001907713.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001907714.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001907715.1 silverDB:etchr01769 YP_001907716.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001907717.1 catalyzes the formation of betaine from betaine aldehyde YP_001907718.1 silverDB:etchr01772 YP_001907719.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001907720.1 silverDB:etchr01774 YP_001907721.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001907722.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001907723.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001907724.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001907725.1 silverDB:etchr01779 YP_001907726.1 transcription regulator that can both activate or repress expression YP_001907727.1 silverDB:etchr01781 YP_001907728.1 silverDB:etchr01782 YP_001907729.1 silverDB:etchr01783 YP_001907730.1 silverDB:etchr01784 YP_001907731.1 silverDB:etchr01785 YP_001907732.1 silverDB:etchr01786 YP_001907733.1 silverDB:etchr01787 YP_001907734.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001907735.1 silverDB:etchr01789 YP_001907736.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001907737.1 silverDB:etchr01791 YP_001907738.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001907739.1 silverDB:etchr01793 YP_001907740.1 silverDB:etchr01794 YP_001907741.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001907742.1 silverDB:etchr01796 YP_001907743.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001907744.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001907745.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001907746.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001907747.1 silverDB:etchr01803 YP_001907748.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001907749.1 silverDB:etchr01805 YP_001907750.1 silverDB:etchr01806 YP_001907751.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001907752.1 with SufCD activates cysteine desulfurase SufS YP_001907753.1 silverDB:etchr01809 YP_001907754.1 silverDB:etchr01810 YP_001907755.1 silverDB:etchr01811 YP_001907756.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001907757.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001907758.1 silverDB:etchr01814 YP_001907759.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001907760.1 silverDB:etchr01816 YP_001907761.1 silverDB:etchr01817 YP_001907762.1 silverDB:etchr01818 YP_001907763.1 with HmuTU is involved in the transport of hemin YP_001907764.1 silverDB:etchr01820 YP_001907765.1 silverDB:etchr01821 YP_001907766.1 silverDB:etchr01822 YP_001907767.1 silverDB:etchr01823 YP_001907768.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001907769.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001907770.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001907771.1 silverDB:etchr01827 YP_001907772.1 silverDB:etchr01828 YP_001907773.1 silverDB:etchr01829 YP_001907774.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001907775.1 silverDB:etchr01831 YP_001907776.1 silverDB:etchr01832 YP_001907777.1 silverDB:etchr01833 YP_001907778.1 silverDB:etchr01834 YP_001907779.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001907780.1 silverDB:etchr01836 YP_001907781.1 silverDB:etchr01837 YP_001907782.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001907783.1 silverDB:etchr01839 YP_001907784.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001907785.1 3' incision activity; acts with UvrC YP_001907786.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001907787.1 silverDB:etchr01843 YP_001907788.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001907789.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001907790.1 silverDB:etchr01846 YP_001907791.1 silverDB:etchr01847 YP_001907792.1 silverDB:etchr01848 YP_001907793.1 silverDB:etchr01849 YP_001907794.1 silverDB:etchr01850 YP_001907795.1 silverDB:etchr01851 YP_001907796.1 silverDB:etchr01852 YP_001907797.1 silverDB:etchr01853 YP_001907798.1 silverDB:etchr01854 YP_001907799.1 silverDB:etchr01855 YP_001907800.1 silverDB:etchr01856 YP_001907801.1 silverDB:etchr01857 YP_001907802.1 silverDB:etchr01858 YP_001907803.1 silverDB:etchr01859 YP_001907804.1 silverDB:etchr01860 YP_001907805.1 silverDB:etchr01861 YP_001907806.1 silverDB:etchr01862 YP_001907807.1 silverDB:etchr01863 YP_001907808.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001907809.1 silverDB:etchr01865 YP_001907810.1 silverDB:etchr01866 YP_001907811.1 silverDB:etchr01867 YP_001907812.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001907813.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001907814.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001907815.1 silverDB:etchr01871 YP_001907816.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001907817.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001907818.1 silverDB:etchr01874 YP_001907819.1 silverDB:etchr01875 YP_001907820.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001907821.1 silverDB:etchr01877 YP_001907822.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001907823.1 silverDB:etchr01879 YP_001907824.1 silverDB:etchr01880 YP_001907825.1 silverDB:etchr01881 YP_001907826.1 silverDB:etchr01882 YP_001907827.1 silverDB:etchr01883 YP_001907828.1 silverDB:etchr01884 YP_001907829.1 silverDB:etchr01885 YP_001907830.1 silverDB:etchr01886 YP_001907831.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_001907832.1 silverDB:etchr01888 YP_001907833.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_001907834.1 silverDB:etchr01890 YP_001907835.1 silverDB:etchr01891 YP_001907836.1 silverDB:etchr01892 YP_001907837.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. catalytic subunit of a protein translocase YP_001907838.1 silverDB:etchr01894 YP_001907839.1 silverDB:etchr01895 YP_001907840.1 silverDB:etchr01896 YP_001907841.1 silverDB:etchr01897 YP_001907842.1 silverDB:etchr01898 YP_001907843.1 silverDB:etchr01899 YP_001907844.1 silverDB:etchr01900 YP_001907845.1 silverDB:etchr01902 YP_001907846.1 silverDB:etchr01903 YP_001907847.1 silverDB:etchr01904 YP_001907848.1 silverDB:etchr01905 YP_001907849.1 silverDB:etchr01906 YP_001907850.1 silverDB:etchr01907 YP_001907851.1 silverDB:etchr01908 YP_001907852.1 silverDB:etchr01909 YP_001907853.1 silverDB:etchr01910 YP_001907854.1 silverDB:etchr01911 YP_001907855.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001907856.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001907857.1 silverDB:etchr01914 YP_001907858.1 silverDB:etchr01915 YP_001907859.1 silverDB:etchr01916 YP_001907860.1 silverDB:etchr01917 YP_001907861.1 silverDB:etchr01919 YP_001907862.1 silverDB:etchr01920 YP_001907863.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001907864.1 silverDB:etchr01922 YP_001907865.1 silverDB:etchr01923 YP_001907866.1 silverDB:etchr01924 YP_001907867.1 silverDB:etchr01925 YP_001907868.1 silverDB:etchr01926 YP_001907869.1 silverDB:etchr01927 YP_001907870.1 silverDB:etchr01928 YP_001907871.1 silverDB:etchr01929 YP_001907872.1 silverDB:etchr01930 YP_001907873.1 silverDB:etchr01931 YP_001907874.1 silverDB:etchr01932 YP_001907875.1 silverDB:etchr01933 YP_001907876.1 silverDB:etchr01934 YP_001907877.1 silverDB:etchr01935 YP_001907878.1 silverDB:etchr01936 YP_001907879.1 silverDB:etchr01937 YP_001907880.1 NADP; Converts isocitrate to alpha ketoglutarate YP_001907881.1 silverDB:etchr01939 YP_001907882.1 silverDB:etchr01940 YP_001907883.1 silverDB:etchr01943 YP_001907884.1 silverDB:etchr01944 YP_001907885.1 silverDB:etchr01945 YP_001907886.1 silverDB:etchr01946 YP_001907887.1 silverDB:etchr01947 YP_001907888.1 silverDB:etchr01948 YP_001907889.1 silverDB:etchr01949 YP_001907890.1 silverDB:etchr01950 YP_001907891.1 silverDB:etchr01951 YP_001907892.1 silverDB:etchr01952 YP_001907893.1 silverDB:etchr01953 YP_001907894.1 silverDB:etchr01954 YP_001907895.1 silverDB:etchr01955 YP_001907896.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001907897.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001907898.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001907899.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001907900.1 silverDB:etchr01960 YP_001907901.1 silverDB:etchr01961 YP_001907902.1 silverDB:etchr01962 YP_001907903.1 silverDB:etchr01963 YP_001907904.1 silverDB:etchr01964 YP_001907905.1 silverDB:etchr01965 YP_001907906.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001907907.1 silverDB:etchr01967 YP_001907908.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001907909.1 silverDB:etchr01969 YP_001907910.1 silverDB:etchr01970 YP_001907911.1 silverDB:etchr01971 YP_001907912.1 silverDB:etchr01972 YP_001907913.1 silverDB:etchr01973 YP_001907914.1 silverDB:etchr01974 YP_001907915.1 silverDB:etchr01975 YP_001907916.1 silverDB:etchr01976 YP_001907917.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001907918.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001907919.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001907920.1 involved in type III protein export during flagellum assembly YP_001907921.1 silverDB:etchr01981 YP_001907922.1 silverDB:etchr01982 YP_001907923.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001907924.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001907925.1 silverDB:etchr01985 YP_001907926.1 silverDB:etchr01986 YP_001907927.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001907928.1 silverDB:etchr01988 YP_001907929.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001907930.1 silverDB:etchr01990 YP_001907931.1 silverDB:etchr01991 YP_001907932.1 silverDB:etchr01992; phage-related protein YP_001907933.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001907934.1 silverDB:etchr01994 YP_001907935.1 silverDB:etchr01995 YP_001907936.1 silverDB:etchr01996 YP_001907937.1 silverDB:etchr01997 YP_001907938.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001907939.1 silverDB:etchr01999 YP_001907940.1 silverDB:etchr02000 YP_001907941.1 silverDB:etchr02001 YP_001907942.1 silverDB:etchr02002 YP_001907943.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001907944.1 silverDB:etchr02004 YP_001907945.1 silverDB:etchr02005 YP_001907946.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001907947.1 silverDB:etchr02007 YP_001907948.1 silverDB:etchr02008 YP_001907949.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001907950.1 carries the fatty acid chain in fatty acid biosynthesis YP_001907951.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001907952.1 silverDB:etchr02012 YP_001907953.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001907954.1 silverDB:etchr02014 YP_001907955.1 silverDB:etchr10014 YP_001907956.1 silverDB:etchr02015 YP_001907957.1 silverDB:etchr02016 YP_001907958.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001907959.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001907960.1 silverDB:etchr02019 YP_001907961.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001907962.1 flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001907963.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001907964.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001907965.1 silverDB:etchr02024 YP_001907966.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001907967.1 the hook connects flagellar basal body to the flagellar filament YP_001907968.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001907969.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001907970.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001907971.1 silverDB:etchr02030 YP_001907972.1 silverDB:etchr02031 YP_001907973.1 silverDB:etchr02032 YP_001907974.1 silverDB:etchr02033 YP_001907975.1 silverDB:etchr02036 YP_001907976.1 silverDB:etchr02037 YP_001907977.1 cofactor involved in the reduction of disulfides YP_001907978.1 silverDB:etchr02039 YP_001907979.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001907980.1 silverDB:etchr02041 YP_001907981.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001907982.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001907983.1 silverDB:etchr02044 YP_001907984.1 silverDB:etchr02045 YP_001907985.1 silverDB:etchr02046 YP_001907986.1 silverDB:etchr02047 YP_001907987.1 silverDB:etchr02048 YP_001907988.1 silverDB:etchr02049 YP_001907989.1 silverDB:etchr02050 YP_001907990.1 silverDB:etchr02051 YP_001907991.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001907992.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001907993.1 required for the transfer of succinyl residues to the glucan backbone YP_001907994.1 silverDB:etchr02055 YP_001907995.1 silverDB:etchr02056 YP_001907996.1 silverDB:etchr02057 YP_001907997.1 silverDB:etchr02058 YP_001907998.1 silverDB:etchr02059 YP_001907999.1 silverDB:etchr02060 YP_001908000.1 silverDB:etchr02064 YP_001908001.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001908002.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001908003.1 silverDB:etchr02067 YP_001908004.1 silverDB:etchr02068 YP_001908005.1 silverDB:etchr02069 YP_001908006.1 silverDB:etchr02070 YP_001908007.1 silverDB:etchr02071 YP_001908008.1 silverDB:etchr02072 YP_001908009.1 silverDB:etchr02073 YP_001908010.1 silverDB:etchr02074 YP_001908011.1 silverDB:etchr02075 YP_001908012.1 silverDB:etchr02076 YP_001908013.1 silverDB:etchr02077 YP_001908014.1 silverDB:etchr02078 YP_001908015.1 silverDB:etchr02079 YP_001908016.1 silverDB:etchr02080 YP_001908017.1 silverDB:etchr02081 YP_001908018.1 silverDB:etchr02082 YP_001908019.1 silverDB:etchr02083 YP_001908020.1 silverDB:etchr02084 YP_001908021.1 silverDB:etchr02085 YP_001908022.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001908023.1 silverDB:etchr02087 YP_001908024.1 silverDB:etchr02088 YP_001908025.1 silverDB:etchr02089 YP_001908026.1 silverDB:etchr02090 YP_001908027.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001908028.1 silverDB:etchr02092 YP_001908029.1 silverDB:etchr02093 YP_001908030.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001908031.1 silverDB:etchr02095 YP_001908032.1 silverDB:etchr02096 YP_001908033.1 silverDB:etchr02097 YP_001908034.1 silverDB:etchr02098 YP_001908035.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001908036.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001908037.1 silverDB:etchr02101 YP_001908038.1 silverDB:etchr02102 YP_001908039.1 silverDB:etchr02103 YP_001908040.1 silverDB:etchr02104 YP_001908041.1 silverDB:etchr02105 YP_001908042.1 silverDB:etchr02106 YP_001908043.1 catalyzes the release of sulfite from alkanesulfonates YP_001908044.1 silverDB:etchr02108 YP_001908045.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001908046.1 silverDB:etchr02110 YP_001908047.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001908048.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001908049.1 silverDB:etchr02113 YP_001908050.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001908051.1 silverDB:etchr02115 YP_001908052.1 silverDB:etchr02116 YP_001908053.1 silverDB:etchr02117 YP_001908054.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001908055.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001908056.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001908057.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001908058.1 silverDB:etchr02122 YP_001908059.1 silverDB:etchr02123 YP_001908060.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001908061.1 silverDB:etchr02125 YP_001908062.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001908063.1 involved in the transport of lipid A across the inner membrane YP_001908064.1 silverDB:etchr02128 YP_001908065.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001908066.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001908067.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001908068.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001908069.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001908070.1 silverDB:etchr02134 YP_001908071.1 silverDB:etchr02135 YP_001908072.1 silverDB:etchr02136 YP_001908073.1 silverDB:etchr02137 YP_001908074.1 silverDB:etchr02138 YP_001908075.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001908076.1 silverDB:etchr02140 YP_001908077.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001908078.1 silverDB:etchr02142 YP_001908079.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001908080.1 silverDB:etchr02144 YP_001908081.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001908082.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001908083.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001908084.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001908085.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001908086.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001908087.1 silverDB:etchr02151 YP_001908088.1 catalyzes the formation of acetate from pyruvate YP_001908089.1 silverDB:etchr02153 YP_001908090.1 silverDB:etchr02154 YP_001908091.1 silverDB:etchr02155 YP_001908092.1 With ArtMQJI transports arginine across the inner membrane YP_001908093.1 silverDB:etchr02157 YP_001908094.1 with ArtPMJI transports arginine across the inner membrane YP_001908095.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001908096.1 silverDB:etchr02160 YP_001908097.1 silverDB:etchr02161 YP_001908098.1 silverDB:etchr02162 YP_001908099.1 silverDB:etchr02163 YP_001908100.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001908101.1 silverDB:etchr02165 YP_001908102.1 silverDB:etchr02166 YP_001908103.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001908104.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001908105.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001908106.1 silverDB:etchr02170 YP_001908107.1 silverDB:etchr02171 YP_001908108.1 silverDB:etchr02172 YP_001908109.1 silverDB:etchr02173 YP_001908110.1 silverDB:etchr02174 YP_001908111.1 silverDB:etchr02175 YP_001908112.1 silverDB:etchr02176 YP_001908113.1 silverDB:etchr02177 YP_001908114.1 silverDB:etchr02178 YP_001908115.1 silverDB:etchr02179 YP_001908116.1 silverDB:etchr02180 YP_001908117.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001908118.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001908119.1 silverDB:etchr02183 YP_001908120.1 silverDB:etchr02184 YP_001908121.1 silverDB:etchr02185 YP_001908122.1 silverDB:etchr02186 YP_001908123.1 silverDB:etchr02187 YP_001908124.1 silverDB:etchr02188 YP_001908125.1 silverDB:etchr02189 YP_001908126.1 silverDB:etchr02190 YP_001908127.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001908128.1 silverDB:etchr02192 YP_001908129.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001908130.1 silverDB:etchr02194 YP_001908131.1 similar to periplasmic-binding component of ABC transporters YP_001908132.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001908133.1 similar to ATP-binding component of ABC transporters YP_001908134.1 silverDB:etchr02198 YP_001908135.1 silverDB:etchr02199 YP_001908136.1 silverDB:etchr02200 YP_001908137.1 silverDB:etchr02201 YP_001908138.1 silverDB:etchr02202 YP_001908139.1 silverDB:etchr02203 YP_001908140.1 silverDB:etchr02204 YP_001908141.1 silverDB:etchr02205 YP_001908142.1 silverDB:etchr02206 YP_001908143.1 silverDB:etchr02207 YP_001908144.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001908145.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001908146.1 silverDB:etchr02210 YP_001908147.1 silverDB:etchr02211 YP_001908148.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001908149.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001908150.1 silverDB:etchr02214 YP_001908151.1 silverDB:etchr02215 YP_001908152.1 helicase involved in DNA repair and perhaps also replication YP_001908153.1 silverDB:etchr02217 YP_001908154.1 silverDB:etchr02218 YP_001908155.1 silverDB:etchr02219 YP_001908156.1 silverDB:etchr02220 YP_001908157.1 silverDB:etchr02221 YP_001908158.1 silverDB:etchr02222 YP_001908159.1 silverDB:etchr02223 YP_001908160.1 silverDB:etchr02224 YP_001908161.1 silverDB:etchr02225 YP_001908162.1 silverDB:etchr02226 YP_001908163.1 silverDB:etchr02227 YP_001908164.1 silverDB:etchr02228 YP_001908165.1 silverDB:etchr02229 YP_001908166.1 silverDB:etchr02230 YP_001908167.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001908168.1 silverDB:etchr02232 YP_001908169.1 silverDB:etchr02233 YP_001908170.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001908171.1 silverDB:etchr02235 YP_001908172.1 silverDB:etchr02236 YP_001908173.1 silverDB:etchr02237 YP_001908174.1 silverDB:etchr02238 YP_001908175.1 this helicase is not essential cell growth YP_001908176.1 silverDB:etchr02240 YP_001908177.1 silverDB:etchr02241 YP_001908178.1 silverDB:etchr02242 YP_001908179.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001908180.1 silverDB:etchr02244 YP_001908181.1 silverDB:etchr02245 YP_001908182.1 silverDB:etchr02246 YP_001908183.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001908184.1 silverDB:etchr02248 YP_001908185.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001908186.1 silverDB:etchr02250 YP_001908187.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001908188.1 silverDB:etchr02252 YP_001908189.1 silverDB:etchr02253 YP_001908190.1 silverDB:etchr02254 YP_001908191.1 silverDB:etchr02255 YP_001908192.1 silverDB:etchr02256 YP_001908193.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001908194.1 silverDB:etchr02258 YP_001908195.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001908196.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001908197.1 silverDB:etchr02261 YP_001908198.1 with ModCB is involved in the high-affinity transport of molybdate YP_001908199.1 silverDB:etchr02263 YP_001908200.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001908201.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001908202.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001908203.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001908204.1 silverDB:etchr02268 YP_001908205.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001908206.1 silverDB:etchr02270 YP_001908207.1 silverDB:etchr02271 YP_001908208.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001908209.1 silverDB:etchr02273 YP_001908210.1 involved in zinc efflux across the cytoplasmic membrane YP_001908211.1 silverDB:etchr02275 YP_001908212.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001908213.1 silverDB:etchr02277 YP_001908214.1 silverDB:etchr02278 YP_001908215.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001908216.1 silverDB:etchr02280 YP_001908217.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001908218.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001908219.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001908220.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001908221.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001908222.1 silverDB:etchr02286 YP_001908223.1 silverDB:etchr02287 YP_001908224.1 silverDB:etchr02288 YP_001908225.1 silverDB:etchr02289 YP_001908226.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001908227.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001908228.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001908229.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001908230.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001908231.1 silverDB:etchr02295 YP_001908232.1 silverDB:etchr02296 YP_001908233.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001908234.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001908235.1 silverDB:etchr02299 YP_001908236.1 silverDB:etchr02300 YP_001908237.1 silverDB:etchr02301 YP_001908238.1 silverDB:etchr02302 YP_001908239.1 silverDB:etchr02303 YP_001908240.1 silverDB:etchr02304 YP_001908241.1 silverDB:etchr02305 YP_001908242.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001908243.1 silverDB:etchr02307 YP_001908244.1 silverDB:etchr02308 YP_001908245.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001908246.1 negative modulator of the initiation of chromosome replication YP_001908247.1 silverDB:etchr02311 YP_001908248.1 silverDB:etchr02312 YP_001908249.1 silverDB:etchr02313 YP_001908250.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001908251.1 silverDB:etchr02315 YP_001908252.1 silverDB:etchr02316 YP_001908253.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001908254.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001908255.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001908256.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001908257.1 silverDB:etchr02321 YP_001908258.1 silverDB:etchr02322 YP_001908259.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001908260.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001908261.1 silverDB:etchr02325 YP_001908262.1 silverDB:etchr02326 YP_001908263.1 silverDB:etchr02327 YP_001908264.1 silverDB:etchr02328 YP_001908265.1 transfers the fatty acyl group on membrane lipoproteins YP_001908266.1 silverDB:etchr02330 YP_001908267.1 silverDB:etchr02331 YP_001908268.1 silverDB:etchr02332 YP_001908269.1 silverDB:etchr02333 YP_001908270.1 silverDB:etchr02334 YP_001908271.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001908272.1 silverDB:etchr02336 YP_001908273.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001908274.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001908275.1 silverDB:etchr02339 YP_001908276.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001908277.1 silverDB:etchr02341 YP_001908278.1 silverDB:etchr02342 YP_001908279.1 silverDB:etchr02343 YP_001908280.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001908281.1 silverDB:etchr02345 YP_001908282.1 silverDB:etchr02346 YP_001908283.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001908284.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001908285.1 silverDB:etchr02349 YP_001908286.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001908287.1 catalyzes the transfer of palmitate to lipid A YP_001908288.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001908289.1 silverDB:etchr02353 YP_001908290.1 silverDB:etchr02354 YP_001908291.1 silverDB:etchr02355 YP_001908292.1 silverDB:etchr02356 YP_001908293.1 silverDB:etchr02357 YP_001908294.1 silverDB:etchr02358 YP_001908295.1 silverDB:etchr02359 YP_001908296.1 silverDB:etchr02360 YP_001908297.1 silverDB:etchr02361 YP_001908298.1 silverDB:etchr02362 YP_001908299.1 silverDB:etchr02363 YP_001908300.1 silverDB:etchr02364 YP_001908301.1 silverDB:etchr02365 YP_001908302.1 silverDB:etchr02366 YP_001908303.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001908304.1 silverDB:etchr02368 YP_001908305.1 (Polymyxin resistance protein pmrI) [Includes: UDP-glucuronic acid decarboxylase (EC 4.1.1.-) (UDP-GlcUA decarboxylase) (ArnAFT); UDP-4-amino-4-deoxy-L-arabinose formyltransferase (EC 2.1.2.-) (UDP-L-; Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001908306.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001908307.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001908308.1 silverDB:etchr02372 YP_001908309.1 silverDB:etchr02373 YP_001908310.1 silverDB:etchr02374 YP_001908311.1 silverDB:etchr02375 YP_001908312.1 silverDB:etchr02376 YP_001908313.1 silverDB:etchr02377 YP_001908314.1 silverDB:etchr02378 YP_001908315.1 silverDB:etchr02379 YP_001908316.1 silverDB:etchr02380 YP_001908317.1 silverDB:etchr02381 YP_001908318.1 silverDB:etchr02382 YP_001908319.1 silverDB:etchr02383 YP_001908320.1 silverDB:etchr02384 YP_001908321.1 silverDB:etchr02385 YP_001908322.1 silverDB:etchr02386 YP_001908323.1 silverDB:etchr02387 YP_001908324.1 silverDB:etchr02388 YP_001908325.1 silverDB:etchr02389 YP_001908326.1 silverDB:etchr02390 YP_001908327.1 silverDB:etchr02391 YP_001908328.1 silverDB:etchr02392 YP_001908329.1 silverDB:etchr02393 YP_001908330.1 silverDB:etchr02394 YP_001908331.1 silverDB:etchr02395 YP_001908332.1 silverDB:etchr02396 YP_001908333.1 silverDB:etchr02397 YP_001908334.1 silverDB:etchr02398 YP_001908335.1 silverDB:etchr02399 YP_001908336.1 silverDB:etchr02400 YP_001908337.1 silverDB:etchr02401 YP_001908338.1 silverDB:etchr02402 YP_001908339.1 silverDB:etchr02404 YP_001908340.1 silverDB:etchr02405 YP_001908341.1 silverDB:etchr02406 YP_001908342.1 silverDB:etchr02407 YP_001908343.1 silverDB:etchr02408 YP_001908344.1 silverDB:etchr02409 YP_001908345.1 silverDB:etchr02410 YP_001908346.1 silverDB:etchr02411 YP_001908347.1 silverDB:etchr02412 YP_001908348.1 silverDB:etchr02413 YP_001908349.1 silverDB:etchr02414 YP_001908350.1 silverDB:etchr02415 YP_001908351.1 silverDB:etchr02416 YP_001908352.1 silverDB:etchr02417 YP_001908353.1 silverDB:etchr02418 YP_001908354.1 silverDB:etchr02419; phage-related protein (prophage CP4-57 regulatory protein) YP_001908355.1 silverDB:etchr02420 YP_001908356.1 silverDB:etchr02421 YP_001908357.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001908358.1 silverDB:etchr02423 YP_001908359.1 silverDB:etchr02424 YP_001908360.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001908361.1 silverDB:etchr02426 YP_001908362.1 silverDB:etchr02427 YP_001908363.1 silverDB:etchr02428 YP_001908364.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001908365.1 silverDB:etchr02430 YP_001908366.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001908367.1 silverDB:etchr02432 YP_001908368.1 silverDB:etchr02433 YP_001908369.1 silverDB:etchr02434 YP_001908370.1 silverDB:etchr02435 YP_001908371.1 silverDB:etchr02436 YP_001908372.1 silverDB:etchr02438 YP_001908373.1 silverDB:etchr02439 YP_001908374.1 silverDB:etchr02440 YP_001908375.1 silverDB:etchr02441 YP_001908376.1 silverDB:etchr02442 YP_001908377.1 silverDB:etchr02443 YP_001908378.1 silverDB:etchr02444 YP_001908379.1 silverDB:etchr02445 YP_001908380.1 silverDB:etchr02446 YP_001908381.1 silverDB:etchr02447 YP_001908382.1 (UDP-sugar hydrolase and 5'-nucleotidase) (EC 3.6.1.45; EC 3.1.3.5); catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001908383.1 silverDB:etchr02449 YP_001908384.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001908385.1 silverDB:etchr02451 YP_001908386.1 silverDB:etchr02452 YP_001908387.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001908388.1 silverDB:etchr02454 YP_001908389.1 silverDB:etchr02455 YP_001908390.1 silverDB:etchr02456 YP_001908391.1 silverDB:etchr02457 YP_001908392.1 silverDB:etchr02458 YP_001908393.1 molecular chaperone YP_001908394.1 silverDB:etchr02460 YP_001908395.1 silverDB:etchr02461 YP_001908396.1 silverDB:etchr02462 YP_001908397.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001908398.1 silverDB:etchr02464 YP_001908399.1 silverDB:etchr02465 YP_001908400.1 silverDB:etchr02466 YP_001908401.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001908402.1 silverDB:etchr02468 YP_001908403.1 silverDB:etchr02469 YP_001908404.1 silverDB:etchr02470 YP_001908405.1 silverDB:etchr02471 YP_001908406.1 silverDB:etchr02472 YP_001908407.1 silverDB:etchr02473 YP_001908408.1 silverDB:etchr02474 YP_001908409.1 silverDB:etchr02475 YP_001908410.1 silverDB:etchr02476 YP_001908411.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001908412.1 silverDB:etchr02478 YP_001908413.1 silverDB:etchr02479 YP_001908414.1 silverDB:etchr02480 YP_001908415.1 silverDB:etchr02481 YP_001908416.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001908417.1 silverDB:etchr02483 YP_001908418.1 silverDB:etchr02484 YP_001908419.1 silverDB:etchr02485 YP_001908420.1 silverDB:etchr02486 YP_001908421.1 silverDB:etchr02487 YP_001908422.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001908423.1 silverDB:etchr02489 YP_001908424.1 silverDB:etchr02490 YP_001908425.1 silverDB:etchr02491 YP_001908426.1 silverDB:etchr02492 YP_001908427.1 silverDB:etchr02493 YP_001908428.1 binds and unfolds substrates as part of the ClpXP protease YP_001908429.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001908430.1 binds and unfolds substrates as part of the ClpXP protease YP_001908431.1 silverDB:etchr02497 YP_001908432.1 silverDB:etchr02498 YP_001908433.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001908434.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001908435.1 silverDB:etchr02501 YP_001908436.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001908437.1 silverDB:etchr02503 YP_001908438.1 silverDB:etchr02504 YP_001908439.1 silverDB:etchr02505 YP_001908440.1 silverDB:etchr02506 YP_001908441.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001908442.1 silverDB:etchr02508 YP_001908443.1 silverDB:etchr02509 YP_001908444.1 silverDB:etchr02510 YP_001908445.1 silverDB:etchr02511 YP_001908446.1 Required for the synthesis of the thiazole moiety YP_001908447.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001908448.1 silverDB:etchr02514 YP_001908449.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001908450.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001908451.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001908452.1 regulates rRNA biosynthesis by transcriptional antitermination YP_001908453.1 silverDB:etchr02519 YP_001908454.1 silverDB:etchr02520 YP_001908455.1 silverDB:etchr02521 YP_001908456.1 silverDB:etchr02522 YP_001908457.1 silverDB:etchr02523 YP_001908458.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001908459.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001908460.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001908461.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001908462.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001908463.1 silverDB:etchr02529 YP_001908464.1 silverDB:etchr02530 YP_001908465.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001908466.1 silverDB:etchr02532 YP_001908467.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001908468.1 silverDB:etchr02534 YP_001908469.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001908470.1 silverDB:etchr02536 YP_001908471.1 silverDB:etchr02537 YP_001908472.1 silverDB:etchr02538 YP_001908473.1 silverDB:etchr02539 YP_001908474.1 silverDB:etchr02540 YP_001908475.1 silverDB:etchr02541 YP_001908476.1 silverDB:etchr02542 YP_001908477.1 Required for efficient pilin antigenic variation YP_001908478.1 silverDB:etchr02544 YP_001908479.1 silverDB:etchr02545 YP_001908480.1 silverDB:etchr02546 YP_001908481.1 silverDB:etchr02547 YP_001908482.1 silverDB:etchr02548 YP_001908483.1 silverDB:etchr02549 YP_001908484.1 silverDB:etchr02550 YP_001908485.1 silverDB:etchr02551 YP_001908486.1 silverDB:etchr02552 YP_001908487.1 silverDB:etchr02553 YP_001908488.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001908489.1 silverDB:etchr02555 YP_001908490.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001908491.1 silverDB:etchr02557 YP_001908492.1 silverDB:etchr02558 YP_001908493.1 silverDB:etchr02559 YP_001908494.1 silverDB:etchr02560 YP_001908495.1 silverDB:etchr02561 YP_001908496.1 silverDB:etchr02562 YP_001908497.1 silverDB:etchr02563 YP_001908498.1 silverDB:etchr02564 YP_001908499.1 silverDB:etchr02565 YP_001908500.1 silverDB:etchr02566 YP_001908501.1 silverDB:etchr02567 YP_001908502.1 silverDB:etchr02568 YP_001908503.1 silverDB:etchr02569 YP_001908504.1 silverDB:etchr02570 YP_001908505.1 silverDB:etchr02571 YP_001908506.1 silverDB:etchr02572 YP_001908507.1 silverDB:etchr02573 YP_001908508.1 silverDB:etchr02574 YP_001908509.1 silverDB:etchr02575 YP_001908510.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001908511.1 silverDB:etchr02577 YP_001908512.1 silverDB:etchr02578 YP_001908513.1 silverDB:etchr02579 YP_001908514.1 silverDB:etchr02580 YP_001908515.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001908516.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001908517.1 silverDB:etchr02583 YP_001908518.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001908519.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001908520.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001908521.1 silverDB:etchr02587 YP_001908522.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001908523.1 silverDB:etchr02589 YP_001908524.1 silverDB:etchr02590 YP_001908525.1 silverDB:etchr02591 YP_001908526.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001908527.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_001908528.1 silverDB:etchr02594 YP_001908529.1 silverDB:etchr02595 YP_001908530.1 silverDB:etchr02596 YP_001908531.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_001908532.1 silverDB:etchr02598 YP_001908533.1 catalyzes the transfer of an amino moiety YP_001908534.1 silverDB:etchr02600 YP_001908535.1 silverDB:etchr02601 YP_001908536.1 silverDB:etchr02602 YP_001908537.1 silverDB:etchr02603 YP_001908538.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001908539.1 silverDB:etchr02605 YP_001908540.1 silverDB:etchr02606 YP_001908541.1 silverDB:etchr02607 YP_001908542.1 silverDB:etchr02608 YP_001908543.1 silverDB:etchr02609 YP_001908544.1 silverDB:etchr02610 YP_001908545.1 silverDB:etchr02611 YP_001908546.1 silverDB:etchr02612 YP_001908547.1 silverDB:etchr02613 YP_001908548.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001908549.1 silverDB:etchr02615 YP_001908550.1 silverDB:etchr02616 YP_001908551.1 silverDB:etchr02618 YP_001908552.1 silverDB:etchr02619 YP_001908553.1 silverDB:etchr02620 YP_001908554.1 silverDB:etchr02621 YP_001908555.1 3'-5' exonuclease of DNA polymerase III YP_001908556.1 silverDB:etchr02623 YP_001908557.1 silverDB:etchr02624 YP_001908558.1 silverDB:etchr02625 YP_001908559.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001908560.1 silverDB:etchr02627 YP_001908561.1 silverDB:etchr02629 YP_001908562.1 silverDB:etchr02630 YP_001908563.1 silverDB:etchr02631 YP_001908564.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001908565.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001908566.1 silverDB:etchr02634 YP_001908567.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001908568.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001908569.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001908570.1 silverDB:etchr02638 YP_001908571.1 silverDB:etchr02639 YP_001908572.1 silverDB:etchr02640 YP_001908573.1 silverDB:etchr02641 YP_001908574.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001908575.1 silverDB:etchr02643 YP_001908576.1 Essential for efficient processing of 16S rRNA YP_001908577.1 silverDB:etchr02645 YP_001908578.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001908579.1 silverDB:etchr02647 YP_001908580.1 silverDB:etchr02648 YP_001908581.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001908582.1 silverDB:etchr02650 YP_001908583.1 silverDB:etchr02651 YP_001908584.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001908585.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001908586.1 silverDB:etchr02654 YP_001908587.1 silverDB:etchr02655 YP_001908588.1 silverDB:etchr02656 YP_001908589.1 silverDB:etchr02657 YP_001908590.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001908591.1 silverDB:etchr02659 YP_001908592.1 silverDB:etchr02660 YP_001908593.1 silverDB:etchr02661 YP_001908594.1 silverDB:etchr02662 YP_001908595.1 silverDB:etchr02663 YP_001908596.1 silverDB:etchr02664 YP_001908597.1 silverDB:etchr02665 YP_001908598.1 silverDB:etchr02666 YP_001908599.1 silverDB:etchr02667 YP_001908600.1 silverDB:etchr02668 YP_001908601.1 silverDB:etchr02669 YP_001908602.1 silverDB:etchr02670 YP_001908603.1 silverDB:etchr02671 YP_001908604.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_001908605.1 silverDB:etchr02673 YP_001908606.1 silverDB:etchr02674 YP_001908607.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_001908608.1 silverDB:etchr02676 YP_001908609.1 silverDB:etchr02679 YP_001908610.1 silverDB:etchr02680 YP_001908611.1 This protein performs the mismatch recognition step during the DNA repair process YP_001908612.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001908613.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001908614.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001908615.1 Exopolyphosphatase (EC 3.6.1.11)]; [Includes: 5'/3'-nucleotidase (EC 3.1.3.5) (EC 3.1.3.6) (Nucleoside monophosphate phosphohydrolase); catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001908616.1 catalyzes the modification of U13 in tRNA(Glu) YP_001908617.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001908618.1 silverDB:etchr02689 YP_001908619.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001908620.1 silverDB:etchr02691 YP_001908621.1 silverDB:etchr02692 YP_001908622.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001908623.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001908624.1 silverDB:etchr02695 YP_001908625.1 silverDB:etchr02696 YP_001908626.1 silverDB:etchr02697 YP_001908627.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001908628.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001908629.1 silverDB:etchr02700 YP_001908630.1 silverDB:etchr02701 YP_001908631.1 silverDB:etchr02702 YP_001908632.1 silverDB:etchr02703 YP_001908633.1 silverDB:etchr02704 YP_001908634.1 silverDB:etchr02705 YP_001908635.1 silverDB:etchr02706 YP_001908636.1 silverDB:etchr02707 YP_001908637.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001908638.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001908639.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_001908640.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001908641.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001908642.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001908643.1 silverDB:etchr02714 YP_001908644.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001908645.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001908646.1 silverDB:etchr02717 YP_001908647.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001908648.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001908649.1 silverDB:etchr02720 YP_001908650.1 silverDB:etchr02721 YP_001908651.1 silverDB:etchr02722 YP_001908652.1 silverDB:etchr02723 YP_001908653.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001908654.1 silverDB:etchr02725 YP_001908655.1 silverDB:etchr02726 YP_001908656.1 silverDB:etchr02727 YP_001908657.1 silverDB:etchr02728 YP_001908658.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001908659.1 silverDB:etchr02730 YP_001908660.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001908661.1 silverDB:etchr02732 YP_001908662.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001908663.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001908664.1 silverDB:etchr02735 YP_001908665.1 silverDB:etchr02736 YP_001908666.1 silverDB:etchr02737 YP_001908667.1 silverDB:etchr02738 YP_001908668.1 silverDB:etchr02739 YP_001908669.1 silverDB:etchr02740 YP_001908670.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001908671.1 silverDB:etchr02742 YP_001908672.1 silverDB:etchr02743 YP_001908673.1 silverDB:etchr02744 YP_001908674.1 silverDB:etchr02745 YP_001908675.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001908676.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001908677.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001908678.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001908679.1 hydrolyzes diadenosine polyphosphate YP_001908680.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001908681.1 silverDB:etchr02752 YP_001908682.1 silverDB:etchr02753 YP_001908683.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001908684.1 silverDB:etchr02755 YP_001908685.1 transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001908686.1 silverDB:etchr02757 YP_001908687.1 silverDB:etchr02758 YP_001908688.1 silverDB:etchr02759 YP_001908689.1 silverDB:etchr02760 YP_001908690.1 silverDB:etchr02761 YP_001908691.1 silverDB:etchr02762 YP_001908692.1 silverDB:etchr02763 YP_001908693.1 silverDB:etchr02764 YP_001908694.1 controls transcription of galETKM YP_001908695.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001908696.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001908697.1 silverDB:etchr02768 YP_001908698.1 silverDB:etchr02769 YP_001908699.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001908700.1 silverDB:etchr02771 YP_001908701.1 silverDB:etchr02772 YP_001908702.1 5'-3' single-stranded-DNA-specific exonuclease YP_001908703.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001908704.1 silverDB:etchr02775 YP_001908705.1 silverDB:etchr02776 YP_001908706.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001908707.1 silverDB:etchr02778 YP_001908708.1 silverDB:etchr02779 YP_001908709.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001908710.1 silverDB:etchr02781 YP_001908711.1 silverDB:etchr02782 YP_001908712.1 silverDB:etchr02783 YP_001908713.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001908714.1 silverDB:etchr02785 YP_001908715.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001908716.1 silverDB:etchr02787 YP_001908717.1 silverDB:etchr02788 YP_001908718.1 silverDB:etchr02789 YP_001908719.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001908720.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001908721.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001908722.1 silverDB:etchr02793 YP_001908723.1 silverDB:etchr02794 YP_001908724.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001908725.1 silverDB:etchr02796 YP_001908726.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001908727.1 silverDB:etchr02798 YP_001908728.1 silverDB:etchr02799 YP_001908729.1 silverDB:etchr02800 YP_001908730.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001908731.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001908732.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001908733.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001908734.1 silverDB:etchr02805 YP_001908735.1 silverDB:etchr02806 YP_001908736.1 silverDB:etchr02807 YP_001908737.1 silverDB:etchr02808 YP_001908738.1 silverDB:etchr02809 YP_001908739.1 silverDB:etchr02810 YP_001908740.1 catalyzes the formation of putrescine from agmatine YP_001908741.1 silverDB:etchr02812 YP_001908742.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001908743.1 silverDB:etchr02814 YP_001908744.1 silverDB:etchr02815 YP_001908745.1 silverDB:etchr02816 YP_001908746.1 silverDB:etchr02817 YP_001908747.1 silverDB:etchr02818 YP_001908748.1 silverDB:etchr02819 YP_001908749.1 silverDB:etchr02820 YP_001908750.1 silverDB:etchr02821 YP_001908751.1 silverDB:etchr02822 YP_001908752.1 silverDB:etchr02823 YP_001908753.1 silverDB:etchr02824 YP_001908754.1 silverDB:etchr02825 YP_001908755.1 silverDB:etchr02826 YP_001908756.1 silverDB:etchr02827 YP_001908757.1 silverDB:etchr02828 YP_001908758.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001908759.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001908760.1 silverDB:etchr02831 YP_001908761.1 silverDB:etchr02832 YP_001908762.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001908763.1 silverDB:etchr02834 YP_001908764.1 silverDB:etchr02835 YP_001908765.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001908766.1 silverDB:etchr02837 YP_001908767.1 silverDB:etchr02838 YP_001908768.1 silverDB:etchr02839 YP_001908769.1 silverDB:etchr02840 YP_001908770.1 silverDB:etchr02841 YP_001908771.1 silverDB:etchr02842 YP_001908772.1 silverDB:etchr02843 YP_001908773.1 silverDB:etchr02844 YP_001908774.1 silverDB:etchr02845 YP_001908775.1 silverDB:etchr02846 YP_001908776.1 silverDB:etchr02848 YP_001908777.1 silverDB:etchr02849 YP_001908778.1 silverDB:etchr02850 YP_001908779.1 silverDB:etchr02851 YP_001908780.1 silverDB:etchr02852 YP_001908781.1 silverDB:etchr02853 YP_001908782.1 silverDB:etchr02854 YP_001908783.1 silverDB:etchr02855 YP_001908784.1 silverDB:etchr02856 YP_001908785.1 silverDB:etchr02857 YP_001908786.1 silverDB:etchr02858 YP_001908787.1 silverDB:etchr02860 YP_001908788.1 silverDB:etchr02861 YP_001908789.1 silverDB:etchr02862 YP_001908790.1 silverDB:etchr02863 YP_001908791.1 silverDB:etchr02864 YP_001908792.1 silverDB:etchr02865 YP_001908793.1 silverDB:etchr02866 YP_001908794.1 silverDB:etchr02867 YP_001908795.1 silverDB:etchr02868 YP_001908796.1 silverDB:etchr02869 YP_001908797.1 silverDB:etchr02870 YP_001908798.1 silverDB:etchr02871 YP_001908799.1 silverDB:etchr02872 YP_001908800.1 silverDB:etchr02873 YP_001908801.1 silverDB:etchr02874 YP_001908802.1 silverDB:etchr02875 YP_001908803.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001908804.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001908805.1 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme YP_001908806.1 silverDB:etchr02878 YP_001908807.1 silverDB:etchr02879 YP_001908808.1 silverDB:etchr02880 YP_001908809.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001908810.1 silverDB:etchr02882 YP_001908811.1 silverDB:etchr02883 YP_001908812.1 silverDB:etchr02884 YP_001908813.1 silverDB:etchr02885 YP_001908814.1 silverDB:etchr02886 YP_001908815.1 silverDB:etchr02887 YP_001908816.1 silverDB:etchr02888 YP_001908817.1 silverDB:etchr02889 YP_001908818.1 silverDB:etchr02890 YP_001908819.1 silverDB:etchr02891 YP_001908820.1 involved in the import of serine and threonine coupled with the import of sodium YP_001908821.1 silverDB:etchr02893 YP_001908822.1 silverDB:etchr02894 YP_001908823.1 silverDB:etchr02895 YP_001908824.1 silverDB:etchr02896 YP_001908825.1 silverDB:etchr02897 YP_001908826.1 silverDB:etchr02898 YP_001908827.1 silverDB:etchr02899 YP_001908828.1 silverDB:etchr02900 YP_001908829.1 silverDB:etchr02901 YP_001908830.1 silverDB:etchr02902 YP_001908831.1 silverDB:etchr02903 YP_001908832.1 silverDB:etchr02904 YP_001908833.1 silverDB:etchr02905 YP_001908834.1 silverDB:etchr02906 YP_001908835.1 silverDB:etchr02907 YP_001908836.1 silverDB:etchr02908 YP_001908837.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001908838.1 silverDB:etchr02910 YP_001908839.1 silverDB:etchr02911 YP_001908840.1 silverDB:etchr02912 YP_001908841.1 silverDB:etchr02913 YP_001908842.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001908843.1 silverDB:etchr02915 YP_001908844.1 silverDB:etchr02916 YP_001908845.1 silverDB:etchr02917 YP_001908846.1 silverDB:etchr02918 YP_001908847.1 silverDB:etchr02919 YP_001908848.1 silverDB:etchr02920 YP_001908849.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001908850.1 silverDB:etchr02922 YP_001908851.1 silverDB:etchr02923 YP_001908852.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001908853.1 silverDB:etchr02925 YP_001908854.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001908855.1 silverDB:etchr02927 YP_001908856.1 silverDB:etchr02928 YP_001908857.1 silverDB:etchr02929 YP_001908858.1 silverDB:etchr02930 YP_001908859.1 silverDB:etchr02931 YP_001908860.1 silverDB:etchr02932 YP_001908861.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001908862.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001908863.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001908864.1 silverDB:etchr02936 YP_001908865.1 silverDB:etchr02937 YP_001908866.1 silverDB:etchr02938 YP_001908867.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001908868.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001908869.1 binds single-stranded DNA at the primosome assembly site YP_001908870.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001908871.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001908872.1 silverDB:etchr02944 YP_001908873.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001908874.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001908875.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001908876.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001908877.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001908878.1 silverDB:etchr02950 YP_001908879.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001908880.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001908881.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001908882.1 Stimulates the elongation of poly(A) tails YP_001908883.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001908884.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001908885.1 silverDB:etchr02957 YP_001908886.1 possibly involved in cell wall synthesis YP_001908887.1 silverDB:etchr02959 YP_001908888.2 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001908889.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001908890.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001908891.1 silverDB:etchr02963 YP_001908892.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001908893.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001908894.1 silverDB:etchr02966 YP_001908895.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001908896.1 silverDB:etchr02968 YP_001908897.1 silverDB:etchr02969 YP_001908898.1 silverDB:etchr02970 YP_001908899.1 silverDB:etchr02971 YP_001908900.1 silverDB:etchr02972 YP_001908901.1 catalyzes the formation of fumarate from aspartate YP_001908902.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001908903.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001908904.1 silverDB:etchr02976 YP_001908905.1 silverDB:etchr02977 YP_001908906.1 silverDB:etchr02978 YP_001908907.1 silverDB:etchr02979 YP_001908908.1 silverDB:etchr02980 YP_001908909.1 silverDB:etchr02981 YP_001908910.1 silverDB:etchr02982 YP_001908911.1 silverDB:etchr02983 YP_001908912.1 silverDB:etchr02984 YP_001908913.1 silverDB:etchr02985 YP_001908914.1 silverDB:etchr02986 YP_001908915.1 silverDB:etchr02987 YP_001908916.1 silverDB:etchr02988 YP_001908917.1 silverDB:etchr02989 YP_001908918.1 silverDB:etchr02990 YP_001908919.1 silverDB:etchr02991 YP_001908920.1 silverDB:etchr02992 YP_001908921.1 silverDB:etchr02993 YP_001908922.1 silverDB:etchr02994 YP_001908923.1 silverDB:etchr02995 YP_001908924.1 silverDB:etchr02996 YP_001908925.1 silverDB:etchr02997 YP_001908926.1 silverDB:etchr02998 YP_001908927.1 silverDB:etchr02999 YP_001908928.1 silverDB:etchr03000 YP_001908929.1 silverDB:etchr03001 YP_001908930.1 silverDB:etchr03002 YP_001908931.1 silverDB:etchr03003 YP_001908932.1 silverDB:etchr03004 YP_001908933.1 silverDB:etchr03005 YP_001908934.1 silverDB:etchr03006 YP_001908935.1 silverDB:etchr03007 YP_001908936.1 silverDB:etchr03008 YP_001908937.1 silverDB:etchr03009 YP_001908938.1 silverDB:etchr03010 YP_001908939.1 silverDB:etchr03011 YP_001908940.1 silverDB:etchr03012 YP_001908941.1 silverDB:etchr03013 YP_001908942.1 silverDB:etchr03014 YP_001908943.1 silverDB:etchr03015 YP_001908944.1 silverDB:etchr03016 YP_001908945.1 silverDB:etchr03017 YP_001908946.1 silverDB:etchr03018 YP_001908947.1 silverDB:etchr03019 YP_001908948.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport YP_001908949.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon YP_001908950.1 silverDB:etchr03022 YP_001908951.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) YP_001908952.1 part of the FecBCDE citrate-dependent iron (III) transport system YP_001908953.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. YP_001908954.1 Part of the FecBCDE citrate-dependent iron (III) transport system YP_001908955.1 silverDB:etchr03027 YP_001908956.1 silverDB:etchr03028 YP_001908957.1 silverDB:etchr03029 YP_001908958.1 silverDB:etchr03030 YP_001908959.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_001908960.1 silverDB:etchr03032 YP_001908961.1 silverDB:etchr03033 YP_001908962.1 silverDB:etchr03034 YP_001908963.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_001908964.1 silverDB:etchr03036 YP_001908965.1 silverDB:etchr03037 YP_001908966.1 silverDB:etchr03038 YP_001908967.1 silverDB:etchr03039 YP_001908968.1 silverDB:etchr03040 YP_001908969.1 silverDB:etchr03041 YP_001908970.1 silverDB:etchr03042 YP_001908971.1 silverDB:etchr03043 YP_001908972.1 silverDB:etchr03044 YP_001908973.1 silverDB:etchr03045 YP_001908974.1 silverDB:etchr03046 YP_001908975.1 silverDB:etchr03047 YP_001908976.1 silverDB:etchr03048 YP_001908977.1 silverDB:etchr03049 YP_001908978.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001908979.1 silverDB:etchr03051 YP_001908980.1 silverDB:etchr03052 YP_001908981.1 silverDB:etchr03053 YP_001908982.1 silverDB:etchr03054 YP_001908983.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001908984.1 silverDB:etchr03056 YP_001908985.1 silverDB:etchr03057 YP_001908986.1 silverDB:etchr03058 YP_001908987.1 silverDB:etchr03059 YP_001908988.1 silverDB:etchr03060 YP_001908989.1 silverDB:etchr03061 YP_001908990.1 silverDB:etchr03062 YP_001908991.1 silverDB:etchr03063 YP_001908992.1 silverDB:etchr03064 YP_001908993.1 silverDB:etchr03065 YP_001908994.1 regulates genes involved in response to oxidative stress YP_001908995.1 silverDB:etchr03068 YP_001908996.1 silverDB:etchr03069 YP_001908997.1 silverDB:etchr03070 YP_001908998.1 silverDB:etchr03071 YP_001908999.1 silverDB:etchr03072 YP_001909000.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001909001.1 silverDB:etchr03074 YP_001909002.1 silverDB:etchr03075 YP_001909003.1 silverDB:etchr03076 YP_001909004.1 silverDB:etchr03077 YP_001909005.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001909006.1 silverDB:etchr03079 YP_001909007.1 silverDB:etchr03080 YP_001909008.1 silverDB:etchr03081 YP_001909009.1 silverDB:etchr03082 YP_001909010.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001909011.1 silverDB:etchr03084 YP_001909012.1 silverDB:etchr03085 YP_001909013.1 silverDB:etchr03086 YP_001909014.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001909015.1 Represses a number of genes involved in the response to DNA damage YP_001909016.1 silverDB:etchr03089 YP_001909017.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001909018.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001909019.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001909020.1 silverDB:etchr03093 YP_001909021.1 silverDB:etchr03094 YP_001909022.1 silverDB:etchr03095 YP_001909023.1 silverDB:etchr03096 YP_001909024.1 silverDB:etchr03097 YP_001909025.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001909026.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001909027.1 silverDB:etchr03100 YP_001909028.1 silverDB:etchr03101 YP_001909029.1 silverDB:etchr03102 YP_001909030.1 silverDB:etchr03103 YP_001909031.1 silverDB:etchr03104 YP_001909032.1 silverDB:etchr03105 YP_001909033.1 silverDB:etchr03106 YP_001909034.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001909035.1 silverDB:etchr03108 YP_001909036.1 silverDB:etchr03109 YP_001909037.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001909038.1 silverDB:etchr03113 YP_001909039.1 silverDB:etchr03114 YP_001909040.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001909041.1 silverDB:etchr03116 YP_001909042.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001909043.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001909044.1 silverDB:etchr03119 YP_001909045.1 silverDB:etchr03120 YP_001909046.1 silverDB:etchr03121 YP_001909047.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001909048.1 silverDB:etchr03123 YP_001909049.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001909050.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001909051.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001909052.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001909053.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001909054.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001909055.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001909056.1 late assembly protein YP_001909057.1 silverDB:etchr03131 YP_001909058.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001909059.1 binds 5S rRNA along with protein L5 and L25 YP_001909060.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001909061.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001909062.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001909063.1 silverDB:etchr03137 YP_001909064.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001909065.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001909066.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001909067.1 silverDB:etchr03141 YP_001909068.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001909069.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001909070.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001909071.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001909072.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001909073.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001909074.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001909075.1 silverDB:etchr03149 YP_001909076.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001909077.1 silverDB:etchr03151 YP_001909078.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001909079.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001909080.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001909081.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001909082.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001909083.1 silverDB:etchr03157 YP_001909084.1 silverDB:etchr03158 YP_001909085.1 silverDB:etchr03159 YP_001909086.1 rotamase YP_001909087.1 silverDB:etchr03161 YP_001909088.1 rotamase YP_001909089.1 silverDB:etchr03163 YP_001909090.1 involved in potassium efflux YP_001909091.1 required for KefB activity YP_001909092.1 silverDB:etchr03166 YP_001909093.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001909094.1 silverDB:etchr03168 YP_001909095.1 silverDB:etchr03169 YP_001909096.1 silverDB:etchr03170 YP_001909097.1 silverDB:etchr03171 YP_001909098.1 silverDB:etchr03172 YP_001909099.1 silverDB:etchr03173 YP_001909100.1 silverDB:etchr03174 YP_001909101.1 silverDB:etchr03175 YP_001909102.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001909103.1 silverDB:etchr03177 YP_001909104.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001909105.1 silverDB:etchr03179 YP_001909106.1 silverDB:etchr03180 YP_001909107.1 silverDB:etchr03181 YP_001909108.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001909109.1 silverDB:etchr03185 YP_001909110.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001909111.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001909112.1 silverDB:etchr03188 YP_001909113.1 silverDB:etchr03189 YP_001909114.1 silverDB:etchr03190 YP_001909115.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001909116.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001909117.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001909118.1 silverDB:etchr03194 YP_001909119.1 silverDB:etchr03195 YP_001909120.1 silverDB:etchr03196 YP_001909121.1 silverDB:etchr03197 YP_001909122.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001909123.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001909124.1 silverDB:etchr03200 YP_001909125.1 silverDB:etchr03201 YP_001909126.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001909127.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001909128.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001909129.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001909130.1 silverDB:etchr03206 YP_001909131.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001909132.1 silverDB:etchr03208 YP_001909133.1 silverDB:etchr03209 YP_001909134.1 silverDB:etchr03210 YP_001909135.1 silverDB:etchr03211 YP_001909136.1 silverDB:etchr03212 YP_001909137.1 silverDB:etchr03213 YP_001909138.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001909139.1 silverDB:etchr03215 YP_001909140.1 amylomaltase; acts to release glucose from maltodextrins YP_001909141.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001909142.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001909143.1 silverDB:etchr03221; phage-related protein YP_001909144.1 silverDB:etchr03222 YP_001909145.1 silverDB:etchr03223 YP_001909146.1 silverDB:etchr03224 YP_001909147.1 silverDB:etchr03225 YP_001909148.1 silverDB:etchr03226 YP_001909149.1 silverDB:etchr03227 YP_001909150.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001909151.1 silverDB:etchr03229 YP_001909152.1 silverDB:etchr03230 YP_001909153.1 silverDB:etchr03231 YP_001909154.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001909155.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001909156.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001909157.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001909158.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001909159.1 silverDB:etchr03237 YP_001909160.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001909161.1 silverDB:etchr03239 YP_001909162.1 silverDB:etchr03240 YP_001909163.1 silverDB:etchr03241 YP_001909164.1 silverDB:etchr03242 YP_001909165.1 silverDB:etchr03244 YP_001909166.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_001909167.1 silverDB:etchr03246 YP_001909168.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001909169.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001909170.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001909171.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001909172.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001909173.1 silverDB:etchr03252 YP_001909174.1 silverDB:etchr03253 YP_001909175.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001909176.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001909177.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001909178.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001909179.1 silverDB:etchr03258 YP_001909180.1 silverDB:etchr03259 YP_001909181.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001909182.1 ABC transporter membrane protein YP_001909183.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001909184.1 silverDB:etchr03263 YP_001909185.1 catalyzes the methylation of 16S rRNA at position G966 YP_001909186.1 silverDB:etchr03265 YP_001909187.1 silverDB:etchr03266 YP_001909188.1 silverDB:etchr03267 YP_001909189.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001909190.1 silverDB:etchr03269 YP_001909191.1 silverDB:etchr03270 YP_001909192.1 silverDB:etchr03271 YP_001909193.1 silverDB:etchr03272 YP_001909194.1 silverDB:etchr03273 YP_001909195.1 silverDB:etchr03274 YP_001909196.1 silverDB:etchr03275 YP_001909197.1 silverDB:etchr03276 YP_001909198.1 silverDB:etchr03277 YP_001909199.1 silverDB:etchr03278 YP_001909200.1 silverDB:etchr03279 YP_001909201.1 silverDB:etchr03280 YP_001909202.1 silverDB:etchr03281 YP_001909203.1 silverDB:etchr03282 YP_001909204.1 silverDB:etchr03283 YP_001909205.1 silverDB:etchr03284 YP_001909206.1 silverDB:etchr03285 YP_001909207.1 silverDB:etchr03286 YP_001909208.1 silverDB:etchr03287 YP_001909209.1 silverDB:etchr03288 YP_001909210.1 silverDB:etchr03289 YP_001909211.1 silverDB:etchr03290 YP_001909212.1 silverDB:etchr03291 YP_001909213.1 silverDB:etchr03292 YP_001909214.1 silverDB:etchr03293 YP_001909215.1 silverDB:etchr03294 YP_001909216.1 silverDB:etchr03295 YP_001909217.1 silverDB:etchr03296 YP_001909218.1 silverDB:etchr03297 YP_001909219.1 silverDB:etchr03298 YP_001909220.1 silverDB:etchr03299 YP_001909221.1 catalyzes the formation of L-proline from L-ornithine YP_001909222.1 silverDB:etchr03301 YP_001909223.1 silverDB:etchr03302 YP_001909224.1 silverDB:etchr03303 YP_001909225.1 silverDB:etchr03304 YP_001909226.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001909227.1 silverDB:etchr03306 YP_001909228.1 SAM-dependent methyltransferase YP_001909229.1 silverDB:etchr03308 YP_001909230.1 silverDB:etchr03309 YP_001909231.1 silverDB:etchr03310 YP_001909232.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001909233.1 silverDB:etchr03312 YP_001909234.1 silverDB:etchr03313 YP_001909235.1 silverDB:etchr03314 YP_001909236.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001909237.1 silverDB:etchr03316 YP_001909238.1 silverDB:etchr03317 YP_001909239.1 silverDB:etchr03318 YP_001909240.1 silverDB:etchr03319 YP_001909241.1 silverDB:etchr03320 YP_001909242.1 silverDB:etchr03321 YP_001909243.1 silverDB:etchr03322 YP_001909244.1 silverDB:etchr03323 YP_001909245.1 silverDB:etchr03324 YP_001909246.1 silverDB:etchr03325 YP_001909247.1 silverDB:etchr03326 YP_001909248.1 silverDB:etchr03327 YP_001909249.1 silverDB:etchr03328 YP_001909250.1 silverDB:etchr03329 YP_001909251.1 silverDB:etchr03330 YP_001909252.1 silverDB:etchr03331 YP_001909253.1 silverDB:etchr03333 YP_001909254.1 silverDB:etchr03334 YP_001909255.1 silverDB:etchr03335 YP_001909256.1 silverDB:etchr03336 YP_001909257.1 silverDB:etchr03337 YP_001909258.1 silverDB:etchr03338 YP_001909259.1 silverDB:etchr03339 YP_001909260.1 silverDB:etchr03340 YP_001909261.1 silverDB:etchr03341 YP_001909262.1 silverDB:etchr03342 YP_001909263.1 silverDB:etchr03343 YP_001909264.1 silverDB:etchr03344 YP_001909265.1 silverDB:etchr03345 YP_001909266.1 silverDB:etchr03346 YP_001909267.1 silverDB:etchr03347 YP_001909268.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001909269.1 silverDB:etchr03349 YP_001909270.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001909271.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001909272.1 silverDB:etchr03352 YP_001909273.1 silverDB:etchr03353 YP_001909274.1 silverDB:etchr03354 YP_001909275.1 silverDB:etchr03355 YP_001909276.1 silverDB:etchr03356 YP_001909277.1 silverDB:etchr03357 YP_001909278.1 silverDB:etchr03358 YP_001909279.1 silverDB:etchr03359 YP_001909280.1 silverDB:etchr03360 YP_001909281.1 silverDB:etchr03361 YP_001909282.1 silverDB:etchr03362 YP_001909283.1 silverDB:etchr03363 YP_001909284.1 silverDB:etchr03364 YP_001909285.1 silverDB:etchr03365 YP_001909286.1 silverDB:etchr03366 YP_001909287.1 silverDB:etchr03367 YP_001909288.1 silverDB:etchr03368 YP_001909289.1 in Escherichia coli this protein is involved in flagellar function YP_001909290.1 silverDB:etchr03370 YP_001909291.1 silverDB:etchr03371 YP_001909292.1 involved in the transport of C4-dicarboxylates across the membrane YP_001909293.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli YP_001909294.1 silverDB:etchr03374 YP_001909295.1 silverDB:etchr03375 YP_001909296.1 silverDB:etchr03376 YP_001909297.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001909298.1 silverDB:etchr03378 YP_001909299.1 silverDB:etchr03379 YP_001909300.1 silverDB:etchr03380 YP_001909301.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001909302.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001909303.1 silverDB:etchr03383 YP_001909304.1 transports peptides consisting of two or three amino acids YP_001909305.1 silverDB:etchr03385 YP_001909306.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001909307.1 silverDB:etchr03387 YP_001909308.1 silverDB:etchr03388 YP_001909309.1 silverDB:etchr03389 YP_001909310.1 silverDB:etchr03390 YP_001909311.1 silverDB:etchr03391 YP_001909312.1 silverDB:etchr03392 YP_001909313.1 silverDB:etchr03393 YP_001909314.1 silverDB:etchr03394 YP_001909315.1 silverDB:etchr03395 YP_001909316.1 silverDB:etchr03396 YP_001909317.1 silverDB:etchr03397 YP_001909318.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001909319.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001909320.1 silverDB:etchr03400 YP_001909321.1 silverDB:etchr03401 YP_001909322.1 silverDB:etchr03402 YP_001909323.1 silverDB:etchr03403 YP_001909324.1 silverDB:etchr03404 YP_001909325.1 silverDB:etchr03405 YP_001909326.1 Acts as a repressor of the mtlAD operon YP_001909327.1 silverDB:etchr03407 YP_001909328.1 silverDB:etchr03408 YP_001909329.1 silverDB:etchr03409 YP_001909330.1 silverDB:etchr03410 YP_001909331.1 silverDB:etchr03411 YP_001909332.1 silverDB:etchr03412 YP_001909333.1 silverDB:etchr03413 YP_001909334.1 silverDB:etchr03414 YP_001909335.1 silverDB:etchr03415 YP_001909336.1 silverDB:etchr03416 YP_001909337.1 silverDB:etchr03417 YP_001909338.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001909339.1 required for the formation of active formate dehydrogenase YP_001909340.1 silverDB:etchr03420 YP_001909341.1 silverDB:etchr03421 YP_001909342.1 silverDB:etchr03422 YP_001909343.1 silverDB:etchr03423 YP_001909344.1 silverDB:etchr03424 YP_001909345.1 silverDB:etchr03425 YP_001909346.1 silverDB:etchr03426 YP_001909347.1 silverDB:etchr03427 YP_001909348.1 silverDB:etchr03428 YP_001909349.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001909350.1 silverDB:etchr03430 YP_001909351.1 silverDB:etchr03431 YP_001909352.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001909353.1 silverDB:etchr03433 YP_001909354.1 silverDB:etchr03434 YP_001909355.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001909356.1 negatively supercoils closed circular double-stranded DNA YP_001909357.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001909358.1 binds the polymerase to DNA and acts as a sliding clamp YP_001909359.1 silverDB:etchr03439 YP_001909360.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001909361.1 silverDB:etchr03441 YP_001909362.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001909363.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001909364.1 silverDB:etchr03444 YP_001909365.1 silverDB:etchr03445 YP_001909366.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001909367.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001909368.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001909369.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001909370.1 silverDB:etchr03451 YP_001909371.1 silverDB:etchr10017 YP_001909372.1 silverDB:etchr03452 YP_001909373.1 silverDB:etchr03453 YP_001909374.1 silverDB:etchr03454 YP_001909375.1 silverDB:etchr03455 YP_001909376.1 silverDB:etchr03456 YP_001909377.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001909378.1 [Includes: UDP-N-acetylglucosamine pyrophosphorylase; glucosamine-1-phosphate N-acetyltransferase]; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001909379.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001909380.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001909381.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001909382.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001909383.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001909384.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001909385.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001909386.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001909387.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001909388.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001909389.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001909390.1 silverDB:9p00001 YP_001909391.1 silverDB:9p00002 YP_001909392.1 type III restriction and modification system, similar to LlaFI; silverDB:9p00003 YP_001909393.1 similar to LlaFI; silverDB:9p00004 YP_001909394.1 silverDB:9p00005 YP_001909395.1 silverDB:9p00006 YP_001909396.1 silverDB:9p00007 YP_001909397.1 silverDB:35p00001 YP_001909398.1 silverDB:35p00002 YP_001909399.1 silverDB:35p00003 YP_001909400.1 silverDB:35p00004 YP_001909401.1 silverDB:35p00005 YP_001909402.1 silverDB:35p00006 YP_001909403.1 silverDB:35p00007 YP_001909404.1 silverDB:35p00008 YP_001909405.1 silverDB:35p00009 YP_001909406.1 silverDB:35p00010 YP_001909407.1 silverDB:35p00011 YP_001909408.1 silverDB:35p00012 YP_001909409.1 silverDB:35p00013 YP_001909410.1 silverDB:35p00014 YP_001909411.1 probable involved in prevention of the accumulation of toxic levels of canavanine; silverDB:35p00015 YP_001909412.1 silverDB:35p00016 YP_001909413.1 silverDB:35p00017 YP_001909414.1 silverDB:35p00018 YP_001909415.1 silverDB:35p00019 YP_001909416.1 silverDB:35p00020 YP_001909417.1 silverDB:35p00021 YP_001909418.1 silverDB:35p00022 YP_001909419.1 silverDB:35p00023 YP_001909420.1 silverDB:35p00024 YP_001909421.1 silverDB:35p00025 YP_001909422.1 silverDB:35p00026 YP_001909423.1 silverDB:35p00027 YP_001909424.1 silverDB:35p00028 YP_001909425.1 silverDB:35p00029 YP_001909426.1 silverDB:35p00030 YP_001909427.1 silverDB:35p00031 YP_001909428.1 silverDB:35p00032 YP_001909429.1 silverDB:35p00033 YP_001909430.1 silverDB:35p00034 YP_001909431.1 silverDB:35p00035 YP_001909432.1 silverDB:35p00036 YP_001909433.1 silverDB:35p00037 YP_001909434.1 silverDB:35p00038 YP_001909435.1 silverDB:35p00039 YP_001909436.1 silverDB:35p00040 YP_001909437.1 silverDB:35p00041 YP_001909438.1 silverDB:35p00042 YP_001909439.1 silverDB:49p00001 YP_001909440.1 silverDB:49p00002 YP_001909441.1 silverDB:49p00003 YP_001909442.1 silverDB:49p00004 YP_001909443.1 silverDB:49p00005 YP_001909444.1 silverDB:49p00006 YP_001909445.1 silverDB:49p00007 YP_001909446.1 silverDB:49p00008 YP_001909447.1 silverDB:49p00009 YP_001909448.1 silverDB:49p00010 YP_001909449.1 TrbL/VirB6; silverDB:49p00011 YP_001909450.1 silverDB:49p00012 YP_001909451.1 silverDB:49p00013 YP_001909452.1 silverDB:49p00014 YP_001909453.1 silverDB:49p00015 YP_001909454.1 silverDB:49p00016 YP_001909455.1 silverDB:49p00017 YP_001909456.1 silverDB:49p00018 YP_001909457.1 silverDB:49p00019 YP_001909458.1 silverDB:49p00020 YP_001909459.1 silverDB:49p00021 YP_001909460.1 silverDB:49p00022 YP_001909461.1 silverDB:49p00023 YP_001909462.1 silverDB:49p00024 YP_001909463.1 silverDB:49p00025 YP_001909464.1 silverDB:49p00026 YP_001909465.1 silverDB:49p00027 YP_001909466.1 silverDB:49p00028 YP_001909467.1 silverDB:49p00029 YP_001909468.1 silverDB:49p00030 YP_001909469.1 silverDB:49p00031 YP_001909470.1 silverDB:49p00032 YP_001909471.1 silverDB:49p00033 YP_001909472.1 silverDB:49p00034 YP_001909473.1 silverDB:49p00035 YP_001909474.1 silverDB:49p00036 YP_001909475.1 silverDB:49p00037 YP_001909476.1 silverDB:49p00038 YP_001909477.1 silverDB:49p00039 YP_001909478.1 silverDB:49p00040 YP_001909479.1 silverDB:49p00041 YP_001909480.1 silverDB:49p00042 YP_001909481.1 silverDB:49p00043 YP_001909482.1 silverDB:49p00044 YP_001909483.1 silverDB:49p00045 YP_001909484.1 silverDB:49p00046 YP_001909485.1 silverDB:49p00047 YP_001909486.1 silverDB:49p00048 YP_001909487.1 silverDB:49p00049 YP_001909488.1 silverDB:49p00050 YP_001909489.1 silverDB:49p00051 YP_001909490.1 silverDB:49p00052 YP_001909491.1 silverDB:49p00053 YP_001909492.1 silverDB:49p00054 YP_001909493.1 similar to plasmid encoded protein YcgC; silverDB:49p00055 YP_001909494.1 silverDB:49p00056 YP_001909495.1 silverDB:49p00057 YP_001909496.1 similar to plasmid encoded protein YajA; silverDB:49p00058 YP_001909497.1 silverDB:49p00059 YP_001909498.1 silverDB:49p00060 YP_001909499.1 silverDB:49p00061 YP_001911067.1 silverDB:45p00001 YP_001911068.1 silverDB:45p00002 YP_001911069.1 silverDB:45p00003 YP_001911070.1 silverDB:45p00004 YP_001911071.1 silverDB:45p00005 YP_001911072.1 silverDB:45p00006 YP_001911073.1 silverDB:45p00007 YP_001911074.1 silverDB:45p00008 YP_001911075.1 silverDB:45p00009 YP_001911076.1 silverDB:45p00010 YP_001911077.1 silverDB:45p00011 YP_001911078.1 silverDB:45p00012 YP_001911079.1 silverDB:45p00013 YP_001911080.1 silverDB:45p00014 YP_001911081.1 similar to VirB4 YP_001911082.1 silverDB:45p00016 YP_001911083.1 silverDB:45p00017 YP_001911084.1 silverDB:45p00018 YP_001911085.1 silverDB:45p00019 YP_001911086.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_001911087.1 type IV secretion system pilus assembly protein; similar to F plasmid TraF YP_001911088.1 silverDB:45p00022 YP_001911089.1 silverDB:45p00023 YP_001911090.1 silverDB:45p00024 YP_001911091.1 silverDB:45p00025 YP_001911092.1 silverDB:45p00026 YP_001911093.1 silverDB:45p00027 YP_001911094.1 silverDB:45p00028 YP_001911095.1 silverDB:45p00029 YP_001911096.1 silverDB:45p00030 YP_001911097.1 silverDB:45p00031 YP_001911098.1 silverDB:45p00032 YP_001911099.1 silverDB:45p00033 YP_001911100.1 silverDB:45p00034 YP_001911101.1 silverDB:45p00035 YP_001911102.1 silverDB:45p00036 YP_001911103.1 silverDB:45p00037 YP_001911104.1 silverDB:45p00038 YP_001911105.1 DNA breaking-rejoining enzyme; silverDB:45p00039 YP_001911106.1 silverDB:45p00040 YP_001911107.1 silverDB:45p00041 YP_001911108.1 silverDB:45p00042 YP_001911109.1 silverDB:45p00043 YP_001911110.1 silverDB:45p00044 YP_001911111.1 silverDB:45p00045 YP_001911112.1 silverDB:45p00046