-- dump date 20140619_080712 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_667942.1 110640214 4190978 190..255 1 NC_008253.1 thr operon leader peptide 255 4190978 ECP_0001 Escherichia coli 536 thr operon leader peptide YP_667942.1 190 D 362663 CDS YP_667943.1 110640215 4190979 336..2798 1 NC_008253.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2798 thrA 4190979 thrA Escherichia coli 536 bifunctional aspartokinase I/homoserine dehydrogenase I YP_667943.1 336 D 362663 CDS YP_667944.1 110640216 4190980 2800..3732 1 NC_008253.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3732 4190980 ECP_0003 Escherichia coli 536 homoserine kinase YP_667944.1 2800 D 362663 CDS YP_667945.1 110640217 4190981 3733..5019 1 NC_008253.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5019 4190981 ECP_0004 Escherichia coli 536 threonine synthase YP_667945.1 3733 D 362663 CDS YP_667946.1 110640218 4190982 5058..5237 1 NC_008253.1 hypothetical protein 5237 4190982 ECP_0005 Escherichia coli 536 hypothetical protein YP_667946.1 5058 D 362663 CDS YP_667947.1 110640219 4190983 5243..5530 1 NC_008253.1 periplasmic protein YaaX 5530 4190983 ECP_0006 Escherichia coli 536 periplasmic protein YaaX YP_667947.1 5243 D 362663 CDS YP_667948.1 110640220 4190984 complement(5580..6356) 1 NC_008253.1 hypothetical protein 6356 4190984 ECP_0007 Escherichia coli 536 hypothetical protein YP_667948.1 5580 R 362663 CDS YP_667949.1 110640221 4190985 complement(6426..7856) 1 NC_008253.1 transporter YaaJ 7856 4190985 ECP_0008 Escherichia coli 536 transporter YaaJ YP_667949.1 6426 R 362663 CDS YP_667950.1 110640222 4190986 8137..9090 1 NC_008253.1 transaldolase B 9090 4190986 ECP_0009 Escherichia coli 536 transaldolase B YP_667950.1 8137 D 362663 CDS YP_667951.1 110640223 4190987 9205..9792 1 NC_008253.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein 9792 mogA 4190987 mogA Escherichia coli 536 molybdenum cofactor biosynthesis protein YP_667951.1 9205 D 362663 CDS YP_667952.1 110640224 4190988 complement(9997..10563) 1 NC_008253.1 regulator; hypothetical protein 10563 4190988 ECP_0011 Escherichia coli 536 hypothetical protein YP_667952.1 9997 R 362663 CDS YP_667953.1 110640225 4190989 complement(10712..11425) 1 NC_008253.1 hypothetical protein 11425 4190989 ECP_0012 Escherichia coli 536 hypothetical protein YP_667953.1 10712 R 362663 CDS YP_667954.1 110640226 4190990 complement(11451..11855) 1 NC_008253.1 hypothetical protein 11855 4190990 ECP_0013 Escherichia coli 536 hypothetical protein YP_667954.1 11451 R 362663 CDS YP_667955.1 110640227 4190991 12227..14143 1 NC_008253.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14143 dnaK 4190991 dnaK Escherichia coli 536 molecular chaperone DnaK YP_667955.1 12227 D 362663 CDS YP_667956.2 229560216 4190992 14232..15362 1 NC_008253.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 15362 4190992 ECP_0015 Escherichia coli 536 molecular chaperone DnaJ YP_667956.2 14232 D 362663 CDS YP_667958.1 110640230 4190994 16234..16995 1 NC_008253.1 hypothetical protein 16995 4190994 ECP_0017 Escherichia coli 536 hypothetical protein YP_667958.1 16234 D 362663 CDS YP_667959.1 110640231 4190995 17015..18508 1 NC_008253.1 secreted sulfatase 18508 4190995 ECP_0018 Escherichia coli 536 secreted sulfatase YP_667959.1 17015 D 362663 CDS YP_667960.1 110640232 4187264 18637..19896 1 NC_008253.1 hypothetical protein 19896 4187264 ECP_0019 Escherichia coli 536 hypothetical protein YP_667960.1 18637 D 362663 CDS YP_667961.1 110640233 4187265 20131..21297 1 NC_008253.1 Na(+)/H(+) antiporter 1; exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 21297 nhaA 4187265 nhaA Escherichia coli 536 pH-dependent sodium/proton antiporter YP_667961.1 20131 D 362663 CDS YP_667962.1 110640234 4187266 21357..22262 1 NC_008253.1 Na+/H+ antiporter regulatory protein; Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22262 nhaR 4187266 nhaR Escherichia coli 536 transcriptional activator NhaR YP_667962.1 21357 D 362663 CDS YP_667963.1 110640235 4187267 complement(22358..22621) 1 NC_008253.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 22621 rpsT 4187267 rpsT Escherichia coli 536 30S ribosomal protein S20 YP_667963.1 22358 R 362663 CDS YP_667964.1 110640236 4187268 22950..23891 1 NC_008253.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 23891 4187268 ECP_0023 Escherichia coli 536 bifunctional riboflavin kinase/FMN adenylyltransferase YP_667964.1 22950 D 362663 CDS YP_667965.1 110640237 4187269 23934..26750 1 NC_008253.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 26750 ileS 4187269 ileS Escherichia coli 536 isoleucyl-tRNA synthetase YP_667965.1 23934 D 362663 CDS YP_667966.1 110640238 4187270 26750..27244 1 NC_008253.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 27244 lspA 4187270 lspA Escherichia coli 536 lipoprotein signal peptidase YP_667966.1 26750 D 362663 CDS YP_667967.1 110640239 4187271 27352..27801 1 NC_008253.1 FKBP-type peptidylprolyl isomerase 27801 4187271 ECP_0026 Escherichia coli 536 FKBP-type peptidylprolyl isomerase YP_667967.1 27352 D 362663 CDS YP_667968.1 110640240 4187272 27803..28768 1 NC_008253.1 LytB protein 28768 4187272 ECP_0027 Escherichia coli 536 LytB protein YP_667968.1 27803 D 362663 CDS YP_667969.1 110640241 4187273 28818..29732 1 NC_008253.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 29732 4187273 ECP_0028 Escherichia coli 536 ribonucleoside hydrolase RihC YP_667969.1 28818 D 362663 CDS YP_667970.1 110640242 4187274 29899..30720 1 NC_008253.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 30720 4187274 ECP_0029 Escherichia coli 536 dihydrodipicolinate reductase YP_667970.1 29899 D 362663 CDS YP_667971.1 110640243 4187275 30781..31023 1 NC_008253.1 hypothetical protein 31023 4187275 ECP_0030 Escherichia coli 536 hypothetical protein YP_667971.1 30781 D 362663 CDS YP_667972.1 110640244 4187276 31176..32324 1 NC_008253.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32324 4187276 ECP_0031 Escherichia coli 536 carbamoyl phosphate synthase small subunit YP_667972.1 31176 D 362663 CDS YP_667973.1 110640245 4187277 32342..35560 1 NC_008253.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 35560 carB 4187277 carB Escherichia coli 536 carbamoyl phosphate synthase large subunit YP_667973.1 32342 D 362663 CDS YP_667974.1 110640246 4187278 complement(35568..35786) 1 NC_008253.1 hypothetical protein 35786 4187278 ECP_0033 Escherichia coli 536 hypothetical protein YP_667974.1 35568 R 362663 CDS YP_667975.1 110640247 4187279 35821..36216 1 NC_008253.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 36216 4187279 ECP_0034 Escherichia coli 536 DNA-binding transcriptional activator CaiF YP_667975.1 35821 D 362663 CDS YP_667976.1 110640248 4187280 complement(36335..36925) 1 NC_008253.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 36925 4187280 ECP_0035 Escherichia coli 536 carnitine operon protein CaiE YP_667976.1 36335 R 362663 CDS YP_667977.1 110640249 4187281 complement(36931..37716) 1 NC_008253.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 37716 4187281 ECP_0036 Escherichia coli 536 carnitinyl-CoA dehydratase YP_667977.1 36931 R 362663 CDS YP_667978.1 110640250 4187282 complement(37825..39393) 1 NC_008253.1 crotonobetaine/carnitine-CoA ligase 39393 caiC 4187282 caiC Escherichia coli 536 crotonobetaine/carnitine-CoA ligase YP_667978.1 37825 R 362663 CDS YP_667979.1 110640251 4187283 complement(39451..40668) 1 NC_008253.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 40668 4187283 ECP_0038 Escherichia coli 536 crotonobetainyl-CoA:carnitine CoA-transferase YP_667979.1 39451 R 362663 CDS YP_667980.1 110640252 4189945 complement(40786..41928) 1 NC_008253.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 41928 4189945 ECP_0039 Escherichia coli 536 crotonobetainyl-CoA dehydrogenase YP_667980.1 40786 R 362663 CDS YP_667981.1 110640253 4189946 complement(41959..43473) 1 NC_008253.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 43473 4189946 ECP_0040 Escherichia coli 536 L-carnitine/gamma-butyrobetaine antiporter YP_667981.1 41959 R 362663 CDS YP_667982.1 110640254 4189947 43946..44716 1 NC_008253.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 44716 4189947 ECP_0041 Escherichia coli 536 electron transfer flavoprotein FixA YP_667982.1 43946 D 362663 CDS YP_667983.1 110640255 4189948 44731..45672 1 NC_008253.1 carnitine metabolism; involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 45672 fixB 4189948 fixB Escherichia coli 536 electron transfer flavoprotein FixB YP_667983.1 44731 D 362663 CDS YP_667984.1 110640256 4189949 45723..47009 1 NC_008253.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 47009 4189949 ECP_0043 Escherichia coli 536 oxidoreductase FixC YP_667984.1 45723 D 362663 CDS YP_667985.1 110640257 4189950 47006..47293 1 NC_008253.1 ferredoxin-like protein 47293 4189950 ECP_0044 Escherichia coli 536 ferredoxin-like protein YP_667985.1 47006 D 362663 CDS YP_667986.1 110640258 4189951 47352..48683 1 NC_008253.1 metabolite transport protein YaaU 48683 4189951 ECP_0045 Escherichia coli 536 metabolite transport protein YaaU YP_667986.1 47352 D 362663 CDS YP_667987.1 110640259 4189952 48791..49321 1 NC_008253.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 49321 4189952 ECP_0046 Escherichia coli 536 glutathione-regulated potassium-efflux system ancillary protein KefF YP_667987.1 48791 D 362663 CDS YP_667988.1 110640260 4189953 49314..51176 1 NC_008253.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 51176 4189953 ECP_0047 Escherichia coli 536 glutathione-regulated potassium-efflux system protein KefC YP_667988.1 49314 D 362663 CDS YP_667989.1 110640261 4189954 51368..51847 1 NC_008253.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 51847 folA 4189954 folA Escherichia coli 536 dihydrofolate reductase YP_667989.1 51368 D 362663 CDS YP_667990.1 110640262 4189955 51933..52166 1 NC_008253.1 antitoxin of gyrase inhibiting toxin-antitoxin system 52166 4189955 ECP_0049 Escherichia coli 536 antitoxin of gyrase inhibiting toxin-antitoxin system YP_667990.1 51933 D 362663 CDS YP_667991.1 110640263 4189956 52169..52483 1 NC_008253.1 toxin of gyrase inhibiting toxin-antitoxin system 52483 4189956 ECP_0050 Escherichia coli 536 toxin of gyrase inhibiting toxin-antitoxin system YP_667991.1 52169 D 362663 CDS YP_667992.1 110640264 4189957 complement(52480..53328) 1 NC_008253.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 53328 apaH 4189957 apaH Escherichia coli 536 diadenosine tetraphosphatase YP_667992.1 52480 R 362663 CDS YP_667993.1 110640265 4189958 complement(53335..53712) 1 NC_008253.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 53712 apaG 4189958 apaG Escherichia coli 536 ApaG protein YP_667993.1 53335 R 362663 CDS YP_667994.1 110640266 4189959 complement(53715..54536) 1 NC_008253.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 54536 ksgA 4189959 ksgA Escherichia coli 536 dimethyladenosine transferase YP_667994.1 53715 R 362663 CDS YP_667995.1 110640267 4189960 complement(54533..55501) 1 NC_008253.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 55501 pdxA 4189960 pdxA Escherichia coli 536 4-hydroxythreonine-4-phosphate dehydrogenase YP_667995.1 54533 R 362663 CDS YP_667996.1 110640268 4189774 complement(56860..59214) 1 NC_008253.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 59214 4189774 ECP_0057 Escherichia coli 536 organic solvent tolerance protein YP_667996.1 56860 R 362663 CDS YP_667997.1 110640269 4189775 59469..60284 1 NC_008253.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60284 djlA 4189775 djlA Escherichia coli 536 Dna-J like membrane chaperone protein YP_667997.1 59469 D 362663 CDS YP_667998.1 110640270 4189776 complement(60402..61061) 1 NC_008253.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 61061 4189776 ECP_0059 Escherichia coli 536 23S rRNA/tRNA pseudouridine synthase A YP_667998.1 60402 R 362663 CDS YP_667999.1 110640271 4189777 complement(61073..63979) 1 NC_008253.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 63979 4189777 ECP_0060 Escherichia coli 536 ATP-dependent helicase HepA YP_667999.1 61073 R 362663 CDS YP_668000.1 110640272 4189778 complement(64144..66495) 1 NC_008253.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 66495 4189778 ECP_0061 Escherichia coli 536 DNA polymerase II YP_668000.1 64144 R 362663 CDS YP_668001.1 110640273 4189779 complement(66570..67265) 1 NC_008253.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 67265 araD 4189779 araD Escherichia coli 536 L-ribulose-5-phosphate 4-epimerase YP_668001.1 66570 R 362663 CDS YP_668002.1 110640274 4189780 complement(67550..69052) 1 NC_008253.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 69052 4189780 ECP_0063 Escherichia coli 536 L-arabinose isomerase YP_668002.1 67550 R 362663 CDS YP_668003.1 110640275 4189781 complement(69063..70763) 1 NC_008253.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 70763 4189781 ECP_0064 Escherichia coli 536 ribulokinase YP_668003.1 69063 R 362663 CDS YP_668004.1 110640276 4189782 71102..71947 1 NC_008253.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 71947 4189782 ECP_0065 Escherichia coli 536 DNA-binding transcriptional regulator AraC YP_668004.1 71102 D 362663 CDS YP_668005.1 110640277 4189783 72461..73309 1 NC_008253.1 hypothetical protein 73309 4189783 ECP_0066 Escherichia coli 536 hypothetical protein YP_668005.1 72461 D 362663 CDS YP_668006.1 110640278 4189784 73316..73738 1 NC_008253.1 hypothetical protein 73738 4189784 ECP_0067 Escherichia coli 536 hypothetical protein YP_668006.1 73316 D 362663 CDS YP_668007.1 110640279 4189785 73893..74657 1 NC_008253.1 DedA family integral membrane protein 74657 4189785 ECP_0068 Escherichia coli 536 DedA family integral membrane protein YP_668007.1 73893 D 362663 CDS YP_668008.1 110640280 4189786 complement(74771..75469) 1 NC_008253.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 75469 thiQ 4189786 thiQ Escherichia coli 536 thiamine transporter ATP-binding subunit YP_668008.1 74771 R 362663 CDS YP_668009.1 110640281 4189787 complement(75453..77063) 1 NC_008253.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 77063 thiP 4189787 thiP Escherichia coli 536 thiamine transporter membrane protein YP_668009.1 75453 R 362663 CDS YP_668010.1 110640282 4189788 complement(77039..78022) 1 NC_008253.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 78022 tbpA 4189788 tbpA Escherichia coli 536 thiamine transporter substrate binding subunit YP_668010.1 77039 R 362663 CDS YP_668011.1 110640283 4189789 complement(78186..79841) 1 NC_008253.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 79841 4189789 ECP_0072 Escherichia coli 536 transcriptional regulator SgrR YP_668011.1 78186 R 362663 CDS YP_668012.1 110640284 4189790 complement(80169..80774) 1 NC_008253.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 80774 leuD 4189790 leuD Escherichia coli 536 isopropylmalate isomerase small subunit YP_668012.1 80169 R 362663 CDS YP_668013.1 110640285 4189791 complement(80785..82185) 1 NC_008253.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 82185 4189791 ECP_0074 Escherichia coli 536 isopropylmalate isomerase large subunit YP_668013.1 80785 R 362663 CDS YP_668014.1 110640286 4191365 complement(82188..83279) 1 NC_008253.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 83279 4191365 ECP_0075 Escherichia coli 536 3-isopropylmalate dehydrogenase YP_668014.1 82188 R 362663 CDS YP_668015.1 110640287 4191366 complement(83279..84850) 1 NC_008253.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 84850 4191366 ECP_0076 Escherichia coli 536 2-isopropylmalate synthase YP_668015.1 83279 R 362663 CDS YP_668016.1 110640288 4191367 complement(84942..85028) 1 NC_008253.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 85028 4191367 ECP_0077 Escherichia coli 536 leu operon leader peptide YP_668016.1 84942 R 362663 CDS YP_668017.1 110640289 4191368 85686..86630 1 NC_008253.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 86630 leuO 4191368 leuO Escherichia coli 536 leucine transcriptional activator YP_668017.1 85686 D 362663 CDS YP_668018.1 110640290 4191369 86948..88672 1 NC_008253.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 88672 4191369 ECP_0079 Escherichia coli 536 acetolactate synthase 3 catalytic subunit YP_668018.1 86948 D 362663 CDS YP_668019.1 110640291 4191370 88675..89166 1 NC_008253.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 89166 ilvH 4191370 ilvH Escherichia coli 536 acetolactate synthase 3 regulatory subunit YP_668019.1 88675 D 362663 CDS YP_668021.1 110640293 4191372 89346..90350 1 NC_008253.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 90350 4191372 ECP_0082 Escherichia coli 536 DNA-binding transcriptional regulator FruR YP_668021.1 89346 D 362663 CDS YP_668022.1 110640294 4191373 90952..91410 1 NC_008253.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 91410 4191373 ECP_0083 Escherichia coli 536 cell division protein MraZ YP_668022.1 90952 D 362663 CDS YP_668023.1 110640295 4191374 91412..92353 1 NC_008253.1 S-adenosyl-methyltransferase MraW 92353 mraW 4191374 mraW Escherichia coli 536 S-adenosyl-methyltransferase MraW YP_668023.1 91412 D 362663 CDS YP_668024.1 110640296 4191375 92350..92715 1 NC_008253.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 92715 4191375 ECP_0085 Escherichia coli 536 cell division protein FtsL YP_668024.1 92350 D 362663 CDS YP_668025.1 110640297 4191376 92731..94497 1 NC_008253.1 peptidoglycan synthetase FtsI 94497 4191376 ECP_0086 Escherichia coli 536 peptidoglycan synthetase FtsI YP_668025.1 92731 D 362663 CDS YP_668026.1 110640298 4191377 94484..95971 1 NC_008253.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 95971 murE 4191377 murE Escherichia coli 536 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_668026.1 94484 D 362663 CDS YP_668027.1 110640299 4191378 95968..97326 1 NC_008253.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 97326 murF 4191378 murF Escherichia coli 536 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_668027.1 95968 D 362663 CDS YP_668028.1 110640300 4191379 97320..98402 1 NC_008253.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 98402 mraY 4191379 mraY Escherichia coli 536 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_668028.1 97320 D 362663 CDS YP_668029.1 110640301 4191380 98405..99721 1 NC_008253.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 99721 murD 4191380 murD Escherichia coli 536 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_668029.1 98405 D 362663 CDS YP_668030.1 110640302 4191381 99721..100965 1 NC_008253.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 100965 4191381 ECP_0091 Escherichia coli 536 cell division protein FtsW YP_668030.1 99721 D 362663 CDS YP_668031.1 110640303 4191382 100962..102029 1 NC_008253.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 102029 murG 4191382 murG Escherichia coli 536 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_668031.1 100962 D 362663 CDS YP_668032.1 110640304 4191383 102083..103558 1 NC_008253.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 103558 murC 4191383 murC Escherichia coli 536 UDP-N-acetylmuramate--L-alanine ligase YP_668032.1 102083 D 362663 CDS YP_668033.1 110640305 4191384 103551..104471 1 NC_008253.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 104471 ddl 4191384 ddl Escherichia coli 536 D-alanine--D-alanine ligase YP_668033.1 103551 D 362663 CDS YP_668034.1 110640306 4189640 104473..105303 1 NC_008253.1 involved in septum formation; cell division protein FtsQ 105303 4189640 ECP_0095 Escherichia coli 536 cell division protein FtsQ YP_668034.1 104473 D 362663 CDS YP_668035.1 110640307 4189641 105300..106562 1 NC_008253.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 106562 ftsA 4189641 ftsA Escherichia coli 536 cell division protein FtsA YP_668035.1 105300 D 362663 CDS YP_668036.1 110640308 4189642 106623..107774 1 NC_008253.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 107774 4189642 ECP_0097 Escherichia coli 536 cell division protein FtsZ YP_668036.1 106623 D 362663 CDS YP_668037.1 110640309 4189643 107875..108792 1 NC_008253.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 108792 lpxC 4189643 lpxC Escherichia coli 536 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_668037.1 107875 D 362663 CDS YP_668038.1 110640310 4189644 109023..109535 1 NC_008253.1 regulates SecA expression; secM translational pause allows for the initiation of secA translation; SecA regulator SecM 109535 4189644 ECP_0099 Escherichia coli 536 SecA regulator SecM YP_668038.1 109023 D 362663 CDS YP_668039.1 110640311 4189645 109597..112302 1 NC_008253.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112302 secA 4189645 secA Escherichia coli 536 preprotein translocase subunit SecA YP_668039.1 109597 D 362663 CDS YP_668040.1 110640312 4189646 112362..112760 1 NC_008253.1 nucleoside triphosphate pyrophosphohydrolase 112760 4189646 ECP_0101 Escherichia coli 536 nucleoside triphosphate pyrophosphohydrolase YP_668040.1 112362 D 362663 CDS YP_668041.1 110640313 4189647 complement(112848..113045) 1 NC_008253.1 zinc-binding protein 113045 4189647 ECP_0102 Escherichia coli 536 zinc-binding protein YP_668041.1 112848 R 362663 CDS YP_668042.1 110640314 4189648 complement(113055..113798) 1 NC_008253.1 hypothetical protein 113798 4189648 ECP_0103 Escherichia coli 536 hypothetical protein YP_668042.1 113055 R 362663 CDS YP_668043.1 110640315 4189649 complement(113798..114418) 1 NC_008253.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 114418 coaE 4189649 coaE Escherichia coli 536 dephospho-CoA kinase YP_668043.1 113798 R 362663 CDS YP_668044.1 110640316 4189650 114643..115686 1 NC_008253.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 115686 4189650 ECP_0105 Escherichia coli 536 guanosine 5'-monophosphate oxidoreductase YP_668044.1 114643 D 362663 CDS YP_668045.1 110640317 4189651 complement(115721..116923) 1 NC_008253.1 type IV pilin biogenesis protein 116923 4189651 ECP_0106 Escherichia coli 536 type IV pilin biogenesis protein YP_668045.1 115721 R 362663 CDS YP_668046.1 110640318 4189652 complement(116913..118298) 1 NC_008253.1 hypothetical protein 118298 4189652 ECP_0107 Escherichia coli 536 hypothetical protein YP_668046.1 116913 R 362663 CDS YP_668047.1 110640319 4189653 complement(118308..118748) 1 NC_008253.1 major pilin subunit 118748 4189653 ECP_0108 Escherichia coli 536 major pilin subunit YP_668047.1 118308 R 362663 CDS YP_668048.1 110640320 4189654 complement(118952..119845) 1 NC_008253.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 119845 4189654 ECP_0109 Escherichia coli 536 quinolinate phosphoribosyltransferase YP_668048.1 118952 R 362663 CDS YP_668049.1 110640321 4189655 119933..120484 1 NC_008253.1 N-acetyl-anhydromuranmyl-L-alanine amidase 120484 4189655 ECP_0110 Escherichia coli 536 N-acetyl-anhydromuranmyl-L-alanine amidase YP_668049.1 119933 D 362663 CDS YP_668050.1 110640322 4189656 120481..121335 1 NC_008253.1 transmembrane protein; involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 121335 4189656 ECP_0111 Escherichia coli 536 regulatory protein AmpE YP_668050.1 120481 D 362663 CDS YP_668051.1 110640323 4189657 complement(121378..122748) 1 NC_008253.1 aromatic amino acid transporter 122748 4189657 ECP_0112 Escherichia coli 536 aromatic amino acid transporter YP_668051.1 121378 R 362663 CDS YP_668052.1 110640324 4189658 123276..125057 1 NC_008253.1 colicin 125057 4189658 ECP_0113 Escherichia coli 536 colicin YP_668052.1 123276 D 362663 CDS YP_668053.1 110640325 4190874 125060..125344 1 NC_008253.1 colicin immunity protein 125344 4190874 ECP_0114 Escherichia coli 536 colicin immunity protein YP_668053.1 125060 D 362663 CDS YP_668054.1 110640326 4190875 125512..125751 1 NC_008253.1 uropathogenic specific protein 125751 4190875 ECP_0115 Escherichia coli 536 uropathogenic specific protein YP_668054.1 125512 D 362663 CDS YP_668055.1 110640327 4190876 125752..126042 1 NC_008253.1 colicin immunity protein 126042 4190876 ECP_0116 Escherichia coli 536 colicin immunity protein YP_668055.1 125752 D 362663 CDS YP_668056.1 110640328 4190877 126227..126397 1 NC_008253.1 uropathogenic specific protein 126397 4190877 ECP_0117 Escherichia coli 536 uropathogenic specific protein YP_668056.1 126227 D 362663 CDS YP_668057.1 110640329 4190878 126451..126741 1 NC_008253.1 colicin immunity protein 126741 4190878 ECP_0118 Escherichia coli 536 colicin immunity protein YP_668057.1 126451 D 362663 CDS YP_668058.1 110640330 4190879 127197..127961 1 NC_008253.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 127961 pdhR 4190879 pdhR Escherichia coli 536 transcriptional regulator PdhR YP_668058.1 127197 D 362663 CDS YP_668059.1 110640331 4190880 complement(127958..128140) 1 NC_008253.1 hypothetical protein 128140 4190880 ECP_0120 Escherichia coli 536 hypothetical protein YP_668059.1 127958 R 362663 CDS YP_668060.1 110640332 4190881 128122..130785 1 NC_008253.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 130785 aceE 4190881 aceE Escherichia coli 536 pyruvate dehydrogenase subunit E1 YP_668060.1 128122 D 362663 CDS YP_668061.1 110640333 4190882 130800..132692 1 NC_008253.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 132692 aceF 4190882 aceF Escherichia coli 536 dihydrolipoamide acetyltransferase YP_668061.1 130800 D 362663 CDS YP_668062.1 110640334 4190883 132900..134324 1 NC_008253.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 134324 4190883 ECP_0123 Escherichia coli 536 dihydrolipoamide dehydrogenase YP_668062.1 132900 D 362663 CDS YP_668063.1 110640335 4190884 complement(134566..136323) 1 NC_008253.1 hypothetical protein 136323 4190884 ECP_0124 Escherichia coli 536 hypothetical protein YP_668063.1 134566 R 362663 CDS YP_668064.1 110640336 4190885 136678..139275 1 NC_008253.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 139275 4190885 ECP_0125 Escherichia coli 536 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_668064.1 136678 D 362663 CDS YP_668065.1 110640337 4190886 139450..139812 1 NC_008253.1 hypothetical protein 139812 4190886 ECP_0126 Escherichia coli 536 hypothetical protein YP_668065.1 139450 D 362663 CDS YP_668066.1 110640338 4190887 complement(139850..140644) 1 NC_008253.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 140644 4190887 ECP_0127 Escherichia coli 536 S-adenosylmethionine decarboxylase YP_668066.1 139850 R 362663 CDS YP_668067.1 110640339 4190888 complement(140660..141526) 1 NC_008253.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 141526 4190888 ECP_0128 Escherichia coli 536 spermidine synthase YP_668067.1 140660 R 362663 CDS YP_668068.1 110640340 4190889 complement(141632..141979) 1 NC_008253.1 hypothetical protein 141979 4190889 ECP_0129 Escherichia coli 536 hypothetical protein YP_668068.1 141632 R 362663 CDS YP_668069.1 110640341 4190890 142145..143695 1 NC_008253.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 143695 4190890 ECP_0130 Escherichia coli 536 multicopper oxidase YP_668069.1 142145 D 362663 CDS YP_668070.1 110640342 4190891 complement(143685..143867) 1 NC_008253.1 hypothetical protein 143867 4190891 ECP_0131 Escherichia coli 536 hypothetical protein YP_668070.1 143685 R 362663 CDS YP_668071.1 110640343 4190892 complement(143952..146342) 1 NC_008253.1 glucose dehydrogenase 146342 4190892 ECP_0132 Escherichia coli 536 glucose dehydrogenase YP_668071.1 143952 R 362663 CDS YP_668072.1 110640344 4190893 146652..147083 1 NC_008253.1 hypoxanthine phosphoribosyltransferase 147083 4190893 ECP_0133 Escherichia coli 536 hypoxanthine phosphoribosyltransferase YP_668072.1 146652 D 362663 CDS YP_668073.1 110640345 4189963 complement(147124..147786) 1 NC_008253.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 147786 4189963 ECP_0134 Escherichia coli 536 carbonic anhydrase YP_668073.1 147124 R 362663 CDS YP_668074.1 110640346 4189964 147895..148821 1 NC_008253.1 ABC transporter ATP-binding protein 148821 4189964 ECP_0135 Escherichia coli 536 ABC transporter ATP-binding protein YP_668074.1 147895 D 362663 CDS YP_668075.1 110640347 4189965 148818..149588 1 NC_008253.1 ABC transporter membrane protein 149588 4189965 ECP_0136 Escherichia coli 536 ABC transporter membrane protein YP_668075.1 148818 D 362663 CDS YP_668076.1 110640348 4189966 149693..150133 1 NC_008253.1 PTS system IIA component Yadi 150133 4189966 ECP_0137 Escherichia coli 536 PTS system IIA component Yadi YP_668076.1 149693 D 362663 CDS YP_668077.1 110640349 4189967 150197..151426 1 NC_008253.1 YadE protein, polysaccharide deacetylase 151426 4189967 ECP_0138 Escherichia coli 536 YadE protein, polysaccharide deacetylase YP_668077.1 150197 D 362663 CDS YP_668078.1 110640350 4189968 complement(151430..151810) 1 NC_008253.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 151810 4189968 ECP_0139 Escherichia coli 536 aspartate alpha-decarboxylase YP_668078.1 151430 R 362663 CDS YP_668079.1 110640351 4189969 152084..153016 1 NC_008253.1 hypothetical protein 153016 4189969 ECP_0140 Escherichia coli 536 hypothetical protein YP_668079.1 152084 D 362663 CDS YP_668080.1 110640352 4189970 153085..153288 1 NC_008253.1 transposase, YhgA-like 153288 4189970 ECP_0141 Escherichia coli 536 transposase, YhgA-like YP_668080.1 153085 D 362663 CDS YP_668081.1 110640353 4189971 complement(153370..154221) 1 NC_008253.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 154221 panC 4189971 panC Escherichia coli 536 pantoate--beta-alanine ligase YP_668081.1 153370 R 362663 CDS YP_668082.1 110640354 4189972 complement(154233..155027) 1 NC_008253.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 155027 panB 4189972 panB Escherichia coli 536 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_668082.1 154233 R 362663 CDS YP_668083.1 110640355 4189973 complement(155139..155453) 1 NC_008253.1 hypothetical protein 155453 4189973 ECP_0144 Escherichia coli 536 hypothetical protein YP_668083.1 155139 R 362663 CDS YP_668084.2 162138283 4189974 complement(155557..156426) 1 NC_008253.1 hypothetical protein 156426 4189974 ECP_0145 Escherichia coli 536 hypothetical protein YP_668084.2 155557 R 362663 CDS YP_668085.1 110640357 4189975 complement(156452..157048) 1 NC_008253.1 protein YadK 157048 4189975 ECP_0146 Escherichia coli 536 protein YadK YP_668085.1 156452 R 362663 CDS YP_668086.1 110640358 4189976 complement(157075..157683) 1 NC_008253.1 hypothetical protein 157683 4189976 ECP_0147 Escherichia coli 536 hypothetical protein YP_668086.1 157075 R 362663 CDS YP_668087.1 110640359 4189977 complement(157695..158261) 1 NC_008253.1 hypothetical protein 158261 4189977 ECP_0148 Escherichia coli 536 hypothetical protein YP_668087.1 157695 R 362663 CDS YP_668088.1 110640360 4189978 complement(158278..160866) 1 NC_008253.1 heat shock protein E; similar to the fimbrial usher protein PapC; outer membrane usher protein 160866 4189978 ECP_0149 Escherichia coli 536 outer membrane usher protein YP_668088.1 158278 R 362663 CDS YP_668089.1 110640361 4189979 complement(160901..161641) 1 NC_008253.1 chaperone protein EcpD 161641 4189979 ECP_0150 Escherichia coli 536 chaperone protein EcpD YP_668089.1 160901 R 362663 CDS YP_668090.1 110640362 4189980 complement(161750..162340) 1 NC_008253.1 fimbrial-like protein YadN 162340 4189980 ECP_0151 Escherichia coli 536 fimbrial-like protein YadN YP_668090.1 161750 R 362663 CDS YP_668091.1 110640363 4189981 complement(162702..163181) 1 NC_008253.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 163181 4189981 ECP_0152 Escherichia coli 536 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_668091.1 162702 R 362663 CDS YP_668092.1 110640364 4188992 complement(163178..164596) 1 NC_008253.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 164596 pcnB 4188992 pcnB Escherichia coli 536 poly(A) polymerase YP_668092.1 163178 R 362663 CDS YP_668093.2 162138282 4188993 complement(164635..165531) 1 NC_008253.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 165531 4188993 ECP_0154 Escherichia coli 536 glutamyl-Q tRNA(Asp) synthetase YP_668093.2 164635 R 362663 CDS YP_668094.1 110640366 4188994 complement(165598..166053) 1 NC_008253.1 DnaK transcriptional regulator DksA 166053 4188994 ECP_0155 Escherichia coli 536 DnaK transcriptional regulator DksA YP_668094.1 165598 R 362663 CDS YP_668095.1 110640367 4188995 complement(166231..166935) 1 NC_008253.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 166935 4188995 ECP_0156 Escherichia coli 536 sugar fermentation stimulation protein A YP_668095.1 166231 R 362663 CDS YP_668096.1 110640368 4188996 complement(166950..167489) 1 NC_008253.1 2'-5' RNA ligase 167489 4188996 ECP_0157 Escherichia coli 536 2'-5' RNA ligase YP_668096.1 166950 R 362663 CDS YP_668097.1 110640369 4188997 167554..169983 1 NC_008253.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 169983 4188997 ECP_0158 Escherichia coli 536 ATP-dependent RNA helicase HrpB YP_668097.1 167554 D 362663 CDS YP_668098.1 110640370 4188998 170077..172611 1 NC_008253.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 172611 mrcB 4188998 mrcB Escherichia coli 536 penicillin-binding protein 1b YP_668098.1 170077 D 362663 CDS YP_668099.1 110640371 4188999 172831..175074 1 NC_008253.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 175074 4188999 ECP_0160 Escherichia coli 536 ferrichrome outer membrane transporter YP_668099.1 172831 D 362663 CDS YP_668100.1 110640372 4189000 175125..175922 1 NC_008253.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 175922 4189000 ECP_0161 Escherichia coli 536 iron-hydroxamate transporter ATP-binding subunit YP_668100.1 175125 D 362663 CDS YP_668101.1 110640373 4189001 175922..176812 1 NC_008253.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 176812 4189001 ECP_0162 Escherichia coli 536 iron-hydroxamate transporter substrate-binding subunit YP_668101.1 175922 D 362663 CDS YP_668102.1 110640374 4189002 176809..178791 1 NC_008253.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 178791 4189002 ECP_0163 Escherichia coli 536 iron-hydroxamate transporter permease subunit YP_668102.1 176809 D 362663 CDS YP_668103.1 110640375 4189003 complement(178826..180106) 1 NC_008253.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 180106 4189003 ECP_0164 Escherichia coli 536 glutamate-1-semialdehyde aminotransferase YP_668103.1 178826 R 362663 CDS YP_668104.1 110640376 4189004 180331..181752 1 NC_008253.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 181752 4189004 ECP_0165 Escherichia coli 536 chloride channel protein YP_668104.1 180331 D 362663 CDS YP_668105.1 110640377 4189005 181834..182178 1 NC_008253.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 182178 4189005 ECP_0166 Escherichia coli 536 iron-sulfur cluster insertion protein ErpA YP_668105.1 181834 D 362663 CDS YP_668106.1 110640378 4189006 complement(182225..182848) 1 NC_008253.1 hypothetical protein 182848 4189006 ECP_0167 Escherichia coli 536 hypothetical protein YP_668106.1 182225 R 362663 CDS YP_668107.1 110640379 4189007 complement(183071..183688) 1 NC_008253.1 periplasmic binding protein 183688 4189007 ECP_0168 Escherichia coli 536 periplasmic binding protein YP_668107.1 183071 R 362663 CDS YP_668108.1 110640380 4189008 complement(183681..184379) 1 NC_008253.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 184379 4189008 ECP_0169 Escherichia coli 536 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_668108.1 183681 R 362663 CDS YP_668109.1 110640381 4189009 184463..185980 1 NC_008253.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 185980 dgt 4189009 dgt Escherichia coli 536 deoxyguanosinetriphosphate triphosphohydrolase YP_668109.1 184463 D 362663 CDS YP_668110.1 110640382 4189010 186110..187534 1 NC_008253.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 187534 4189010 ECP_0171 Escherichia coli 536 serine endoprotease YP_668110.1 186110 D 362663 CDS YP_668111.1 110640383 4189011 187689..188846 1 NC_008253.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 188846 4189011 ECP_0172 Escherichia coli 536 carbohydrate diacid transcriptional activator CdaR YP_668111.1 187689 D 362663 CDS YP_668112.1 110640384 4190255 complement(188900..189286) 1 NC_008253.1 hypothetical protein 189286 4190255 ECP_0173 Escherichia coli 536 hypothetical protein YP_668112.1 188900 R 362663 CDS YP_668113.1 110640385 4190256 complement(189596..190420) 1 NC_008253.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 190420 dapD 4190256 dapD Escherichia coli 536 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_668113.1 189596 R 362663 CDS YP_668114.1 110640386 4190257 complement(190451..193123) 1 NC_008253.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 193123 4190257 ECP_0175 Escherichia coli 536 PII uridylyl-transferase YP_668114.1 190451 R 362663 CDS YP_668115.1 110640387 4190258 complement(193185..193979) 1 NC_008253.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 193979 4190258 ECP_0176 Escherichia coli 536 methionine aminopeptidase YP_668115.1 193185 R 362663 CDS YP_668116.1 110640388 4190259 194347..195072 1 NC_008253.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 195072 rpsB 4190259 rpsB Escherichia coli 536 30S ribosomal protein S2 YP_668116.1 194347 D 362663 CDS YP_668117.1 110640389 4190260 195207..196058 1 NC_008253.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 196058 tsf 4190260 tsf Escherichia coli 536 elongation factor Ts YP_668117.1 195207 D 362663 CDS YP_668118.1 110640390 4190261 196205..196930 1 NC_008253.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 196930 pyrH 4190261 pyrH Escherichia coli 536 uridylate kinase YP_668118.1 196205 D 362663 CDS YP_668119.1 110640391 4190262 197080..197637 1 NC_008253.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 197637 frr 4190262 frr Escherichia coli 536 ribosome recycling factor YP_668119.1 197080 D 362663 CDS YP_668120.1 110640392 4190263 197729..198925 1 NC_008253.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 198925 4190263 ECP_0181 Escherichia coli 536 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_668120.1 197729 D 362663 CDS YP_668121.1 110640393 4190264 199111..199872 1 NC_008253.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 199872 4190264 ECP_0182 Escherichia coli 536 undecaprenyl pyrophosphate synthase YP_668121.1 199111 D 362663 CDS YP_668122.1 110640394 4190265 199885..200742 1 NC_008253.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 200742 cdsA 4190265 cdsA Escherichia coli 536 CDP-diglyceride synthase YP_668122.1 199885 D 362663 CDS YP_668123.1 110640395 4190266 200754..202106 1 NC_008253.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 202106 4190266 ECP_0184 Escherichia coli 536 zinc metallopeptidase RseP YP_668123.1 200754 D 362663 CDS YP_668124.1 110640396 4190267 202136..204568 1 NC_008253.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 204568 4190267 ECP_0185 Escherichia coli 536 outer membrane protein assembly factor YaeT YP_668124.1 202136 D 362663 CDS YP_668125.1 110640397 4190268 204690..205175 1 NC_008253.1 periplasmic chaperone 205175 4190268 ECP_0186 Escherichia coli 536 periplasmic chaperone YP_668125.1 204690 D 362663 CDS YP_668126.1 110640398 4190269 205179..206204 1 NC_008253.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 206204 lpxD 4190269 lpxD Escherichia coli 536 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_668126.1 205179 D 362663 CDS YP_668127.1 110640399 4190270 206309..206764 1 NC_008253.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 206764 fabZ 4190270 fabZ Escherichia coli 536 (3R)-hydroxymyristoyl-ACP dehydratase YP_668127.1 206309 D 362663 CDS YP_668128.1 110640400 4190271 206768..207556 1 NC_008253.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 207556 4190271 ECP_0189 Escherichia coli 536 UDP-N-acetylglucosamine acyltransferase YP_668128.1 206768 D 362663 CDS YP_668129.1 110640401 4190272 207556..208704 1 NC_008253.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 208704 lpxB 4190272 lpxB Escherichia coli 536 lipid-A-disaccharide synthase YP_668129.1 207556 D 362663 CDS YP_668130.1 110640402 4190273 208701..209297 1 NC_008253.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 209297 rnhB 4190273 rnhB Escherichia coli 536 ribonuclease HII YP_668130.1 208701 D 362663 CDS YP_668131.1 110640403 4191936 209334..212816 1 NC_008253.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 212816 dnaE 4191936 dnaE Escherichia coli 536 DNA polymerase III subunit alpha YP_668131.1 209334 D 362663 CDS YP_668132.1 110640404 4191937 212829..213788 1 NC_008253.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 213788 4191937 ECP_0193 Escherichia coli 536 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_668132.1 212829 D 362663 CDS YP_668133.1 110640405 4191938 213886..216027 1 NC_008253.1 lysine decarboxylase, constitutive 216027 4191938 ECP_0194 Escherichia coli 536 lysine decarboxylase, constitutive YP_668133.1 213886 D 362663 CDS YP_668134.1 110640406 4191939 216084..216473 1 NC_008253.1 hypothetical protein 216473 4191939 ECP_0195 Escherichia coli 536 hypothetical protein YP_668134.1 216084 D 362663 CDS YP_668135.1 110640407 4191940 216538..217851 1 NC_008253.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 217851 tilS 4191940 tilS Escherichia coli 536 tRNA(Ile)-lysidine synthetase YP_668135.1 216538 D 362663 CDS YP_668136.1 110640408 4191941 complement(217885..218145) 1 NC_008253.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 218145 4191941 ECP_0197 Escherichia coli 536 Rho-binding antiterminator YP_668136.1 217885 R 362663 CDS YP_668137.1 110640409 4191942 complement(218132..218332) 1 NC_008253.1 hypothetical protein 218332 4191942 ECP_0198 Escherichia coli 536 hypothetical protein YP_668137.1 218132 R 362663 CDS YP_668138.1 110640410 4191943 218498..219043 1 NC_008253.1 hypothetical protein 219043 4191943 ECP_0199 Escherichia coli 536 hypothetical protein YP_668138.1 218498 D 362663 CDS YP_668139.1 110640411 4191944 219040..219462 1 NC_008253.1 peptidyl-tRNA hydrolase domain-containing protein 219462 4191944 ECP_0200 Escherichia coli 536 peptidyl-tRNA hydrolase domain-containing protein YP_668139.1 219040 D 362663 CDS YP_668140.1 110640412 4191945 219476..220186 1 NC_008253.1 lipoprotein involved with copper homeostasis and adhesion 220186 4191945 ECP_0201 Escherichia coli 536 lipoprotein involved with copper homeostasis and adhesion YP_668140.1 219476 D 362663 CDS YP_668141.1 110640413 4191946 complement(220342..220896) 1 NC_008253.1 hypothetical protein 220896 4191946 ECP_0202 Escherichia coli 536 hypothetical protein YP_668141.1 220342 R 362663 CDS YP_668142.1 110640414 4191947 complement(220893..221165) 1 NC_008253.1 hypothetical protein 221165 4191947 ECP_0203 Escherichia coli 536 hypothetical protein YP_668142.1 220893 R 362663 CDS YP_668143.1 110640415 4191948 complement(221218..222936) 1 NC_008253.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 222936 4191948 ECP_0204 Escherichia coli 536 prolyl-tRNA synthetase YP_668143.1 221218 R 362663 CDS YP_668144.1 110640416 4191949 complement(223047..223754) 1 NC_008253.1 hypothetical protein 223754 4191949 ECP_0205 Escherichia coli 536 hypothetical protein YP_668144.1 223047 R 362663 CDS YP_668145.1 110640417 4191950 complement(223751..224155) 1 NC_008253.1 outer membrane lipoprotein 224155 rcsF 4191950 rcsF Escherichia coli 536 outer membrane lipoprotein YP_668145.1 223751 R 362663 CDS YP_668146.1 110640418 4191951 complement(224273..225088) 1 NC_008253.1 DL-methionine transporter substrate-binding subunit 225088 metQ 4191951 metQ Escherichia coli 536 DL-methionine transporter substrate-binding subunit YP_668146.1 224273 R 362663 CDS YP_668147.1 110640419 4191952 complement(225128..225781) 1 NC_008253.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 225781 4191952 ECP_0208 Escherichia coli 536 DL-methionine transporter permease YP_668147.1 225128 R 362663 CDS YP_668148.1 110640420 4191953 complement(225774..226805) 1 NC_008253.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 226805 metN 4191953 metN Escherichia coli 536 DL-methionine transporter ATP-binding subunit YP_668148.1 225774 R 362663 CDS YP_668149.1 110640421 4191954 226993..227565 1 NC_008253.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 227565 4191954 ECP_0210 Escherichia coli 536 D,D-heptose 1,7-bisphosphate phosphatase YP_668149.1 226993 D 362663 CDS YP_668150.1 110640422 4187363 233235..234038 1 NC_008253.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 234038 dkgB 4187363 dkgB Escherichia coli 536 2,5-diketo-D-gluconate reductase B YP_668150.1 233235 D 362663 CDS YP_668151.1 110640423 4187364 complement(234035..234949) 1 NC_008253.1 LysR family transcriptional regulator 234949 4187364 ECP_0214 Escherichia coli 536 LysR family transcriptional regulator YP_668151.1 234035 R 362663 CDS YP_668152.1 110640424 4187365 235166..235990 1 NC_008253.1 hypothetical protein 235990 4187365 ECP_0215 Escherichia coli 536 hypothetical protein YP_668152.1 235166 D 362663 CDS YP_668153.1 110640425 4187366 236068..236838 1 NC_008253.1 methyltransferase YafE 236838 4187366 ECP_0216 Escherichia coli 536 methyltransferase YafE YP_668153.1 236068 D 362663 CDS YP_668154.1 110640426 4187367 complement(236887..238245) 1 NC_008253.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 238245 mltD 4187367 mltD Escherichia coli 536 membrane-bound lytic murein transglycosylase D YP_668154.1 236887 R 362663 CDS YP_668155.1 110640427 4187368 complement(238317..239072) 1 NC_008253.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 239072 4187368 ECP_0218 Escherichia coli 536 hydroxyacylglutathione hydrolase YP_668155.1 238317 R 362663 CDS YP_668156.1 110640428 4187369 239103..239828 1 NC_008253.1 hypothetical protein 239828 4187369 ECP_0219 Escherichia coli 536 hypothetical protein YP_668156.1 239103 D 362663 CDS YP_668157.1 110640429 4187370 complement(239825..240292) 1 NC_008253.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 240292 rnhA 4187370 rnhA Escherichia coli 536 ribonuclease H YP_668157.1 239825 R 362663 CDS YP_668158.1 110640430 4187371 240348..241088 1 NC_008253.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 241088 4187371 ECP_0221 Escherichia coli 536 DNA polymerase III subunit epsilon YP_668158.1 240348 D 362663 CDS YP_668159.1 110640431 4187373 241626..242411 1 NC_008253.1 lipoprotein 242411 4187373 ECP_0223 Escherichia coli 536 lipoprotein YP_668159.1 241626 D 362663 CDS YP_668160.1 110640432 4187374 complement(242751..243251) 1 NC_008253.1 hypothetical protein 243251 4187374 ECP_0224 Escherichia coli 536 hypothetical protein YP_668160.1 242751 R 362663 CDS YP_668161.1 110640433 4187375 complement(243248..244606) 1 NC_008253.1 hypothetical protein 244606 4187375 ECP_0225 Escherichia coli 536 hypothetical protein YP_668161.1 243248 R 362663 CDS YP_668162.1 110640434 4187376 complement(244617..248144) 1 NC_008253.1 IcmF-like protein 248144 4187376 ECP_0226 Escherichia coli 536 IcmF-like protein YP_668162.1 244617 R 362663 CDS YP_668163.1 110640435 4187377 complement(248164..249672) 1 NC_008253.1 hypothetical protein 249672 4187377 ECP_0227 Escherichia coli 536 hypothetical protein YP_668163.1 248164 R 362663 CDS YP_668164.1 110640436 4187812 complement(249611..250354) 1 NC_008253.1 hypothetical protein 250354 4187812 ECP_0228 Escherichia coli 536 hypothetical protein YP_668164.1 249611 R 362663 CDS YP_668165.1 110640437 4187813 complement(250351..253113) 1 NC_008253.1 Clp ATPase 253113 4187813 ECP_0229 Escherichia coli 536 Clp ATPase YP_668165.1 250351 R 362663 CDS YP_668166.1 110640438 4187814 complement(253123..253887) 1 NC_008253.1 hypothetical protein 253887 4187814 ECP_0230 Escherichia coli 536 hypothetical protein YP_668166.1 253123 R 362663 CDS YP_668167.1 110640439 4187815 complement(253892..255238) 1 NC_008253.1 hypothetical protein 255238 4187815 ECP_0231 Escherichia coli 536 hypothetical protein YP_668167.1 253892 R 362663 CDS YP_668168.1 110640440 4187816 complement(255241..255765) 1 NC_008253.1 lipoprotein 255765 4187816 ECP_0232 Escherichia coli 536 lipoprotein YP_668168.1 255241 R 362663 CDS YP_668169.1 110640441 4187817 complement(255762..257150) 1 NC_008253.1 hypothetical protein 257150 4187817 ECP_0233 Escherichia coli 536 hypothetical protein YP_668169.1 255762 R 362663 CDS YP_668170.1 110640442 4187818 complement(257059..258108) 1 NC_008253.1 hypothetical protein 258108 4187818 ECP_0234 Escherichia coli 536 hypothetical protein YP_668170.1 257059 R 362663 CDS YP_668171.1 110640443 4187819 complement(258072..259922) 1 NC_008253.1 hypothetical protein 259922 4187819 ECP_0235 Escherichia coli 536 hypothetical protein YP_668171.1 258072 R 362663 CDS YP_668172.1 110640444 4187820 complement(259919..260344) 1 NC_008253.1 hypothetical protein 260344 4187820 ECP_0236 Escherichia coli 536 hypothetical protein YP_668172.1 259919 R 362663 CDS YP_668173.1 110640445 4187821 complement(260349..261833) 1 NC_008253.1 hypothetical protein 261833 4187821 ECP_0237 Escherichia coli 536 hypothetical protein YP_668173.1 260349 R 362663 CDS YP_668174.1 110640446 4187822 complement(261856..262359) 1 NC_008253.1 hypothetical protein 262359 4187822 ECP_0238 Escherichia coli 536 hypothetical protein YP_668174.1 261856 R 362663 CDS YP_668175.1 110640447 4187823 263065..263583 1 NC_008253.1 hemolysin co-regulated protein 263583 4187823 ECP_0239 Escherichia coli 536 hemolysin co-regulated protein YP_668175.1 263065 D 362663 CDS YP_668176.1 110640448 4187824 263804..265786 1 NC_008253.1 Vgr-like protein 265786 4187824 ECP_0240 Escherichia coli 536 Vgr-like protein YP_668176.1 263804 D 362663 CDS YP_668177.1 110640449 4187825 265893..266939 1 NC_008253.1 hypothetical protein 266939 4187825 ECP_0241 Escherichia coli 536 hypothetical protein YP_668177.1 265893 D 362663 CDS YP_668178.1 110640450 4187826 266932..268371 1 NC_008253.1 hypothetical protein 268371 4187826 ECP_0242 Escherichia coli 536 hypothetical protein YP_668178.1 266932 D 362663 CDS YP_668179.1 110640451 4187827 268346..268636 1 NC_008253.1 hypothetical protein 268636 4187827 ECP_0243 Escherichia coli 536 hypothetical protein YP_668179.1 268346 D 362663 CDS YP_668180.1 110640452 4187828 268894..269073 1 NC_008253.1 H repeat-containing Rhs element protein 269073 4187828 ECP_0244 Escherichia coli 536 H repeat-containing Rhs element protein YP_668180.1 268894 D 362663 CDS YP_668181.1 110640453 4187830 269350..269658 1 NC_008253.1 H repeat-containing Rhs element protein 269658 4187830 ECP_0246 Escherichia coli 536 H repeat-containing Rhs element protein YP_668181.1 269350 D 362663 CDS YP_668182.1 110640454 4190615 269887..270390 1 NC_008253.1 hypothetical protein 270390 4190615 ECP_0247 Escherichia coli 536 hypothetical protein YP_668182.1 269887 D 362663 CDS YP_668183.1 110640455 4190616 270484..270972 1 NC_008253.1 hypothetical protein 270972 4190616 ECP_0248 Escherichia coli 536 hypothetical protein YP_668183.1 270484 D 362663 CDS YP_668184.1 110640456 4190617 complement(271243..272013) 1 NC_008253.1 hypothetical protein 272013 4190617 ECP_0249 Escherichia coli 536 hypothetical protein YP_668184.1 271243 R 362663 CDS YP_668185.1 110640457 4190618 272167..272640 1 NC_008253.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 272640 4190618 ECP_0250 Escherichia coli 536 C-lysozyme inhibitor YP_668185.1 272167 D 362663 CDS YP_668186.1 110640458 4190619 complement(272683..275127) 1 NC_008253.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 275127 fadE 4190619 fadE Escherichia coli 536 acyl-CoA dehydrogenase YP_668186.1 272683 R 362663 CDS YP_668187.1 110640459 4190620 275367..275945 1 NC_008253.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 275945 gmhA 4190620 gmhA Escherichia coli 536 phosphoheptose isomerase YP_668187.1 275367 D 362663 CDS YP_668188.1 110640460 4190621 276150..276917 1 NC_008253.1 glutamine amidotransferase 276917 4190621 ECP_0253 Escherichia coli 536 glutamine amidotransferase YP_668188.1 276150 D 362663 CDS YP_668189.1 110640461 4190622 complement(276888..277628) 1 NC_008253.1 hypothetical protein 277628 4190622 ECP_0254 Escherichia coli 536 hypothetical protein YP_668189.1 276888 R 362663 CDS YP_668190.1 110640462 4190623 277931..278689 1 NC_008253.1 lipoprotein 278689 4190623 ECP_0255 Escherichia coli 536 lipoprotein YP_668190.1 277931 D 362663 CDS YP_668191.1 110640463 4190624 278865..279362 1 NC_008253.1 hypothetical protein 279362 4190624 ECP_0256 Escherichia coli 536 hypothetical protein YP_668191.1 278865 D 362663 CDS YP_668192.1 110640464 4190625 complement(279445..279654) 1 NC_008253.1 hypothetical protein 279654 4190625 ECP_0257 Escherichia coli 536 hypothetical protein YP_668192.1 279445 R 362663 CDS YP_668193.1 110640465 4190626 complement(279682..281421) 1 NC_008253.1 flagellar biosynthetic protein FlhA 281421 4190626 ECP_0258 Escherichia coli 536 flagellar biosynthetic protein FlhA YP_668193.1 279682 R 362663 CDS YP_668194.1 110640466 4190627 281381..282151 1 NC_008253.1 hypothetical protein 282151 4190627 ECP_0259 Escherichia coli 536 hypothetical protein YP_668194.1 281381 D 362663 CDS YP_668195.1 110640467 4190628 282222..283277 1 NC_008253.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 283277 4190628 ECP_0260 Escherichia coli 536 DNA polymerase IV YP_668195.1 282222 D 362663 CDS YP_668196.1 110640468 4190629 283329..283622 1 NC_008253.1 antitoxin of the YafO-YafN toxin-antitoxin system 283622 4190629 ECP_0261 Escherichia coli 536 antitoxin of the YafO-YafN toxin-antitoxin system YP_668196.1 283329 D 362663 CDS YP_668197.1 110640469 4190630 283625..284023 1 NC_008253.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 284023 4190630 ECP_0262 Escherichia coli 536 toxin YafO YP_668197.1 283625 D 362663 CDS YP_668198.1 110640470 4190631 284033..284485 1 NC_008253.1 hypothetical protein 284485 4190631 ECP_0263 Escherichia coli 536 hypothetical protein YP_668198.1 284033 D 362663 CDS YP_668199.1 110640471 4190632 284663..285814 1 NC_008253.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 285814 4190632 ECP_0264 Escherichia coli 536 hypothetical protein YP_668199.1 284663 D 362663 CDS YP_668200.2 162138281 4190633 285925..286425 1 NC_008253.1 similar to release factor 1 and 2; peptide chain release factor-like protein 286425 prfH 4190633 prfH Escherichia coli 536 peptide chain release factor-like protein YP_668200.2 285925 D 362663 CDS YP_668201.1 110640473 4190158 complement(286482..287939) 1 NC_008253.1 aminoacyl-histidine dipeptidase 287939 4190158 ECP_0266 Escherichia coli 536 aminoacyl-histidine dipeptidase YP_668201.1 286482 R 362663 CDS YP_668202.1 110640474 4190159 288200..288658 1 NC_008253.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 288658 4190159 ECP_0267 Escherichia coli 536 xanthine-guanine phosphoribosyltransferase YP_668202.1 288200 D 362663 CDS YP_668203.1 110640475 4190160 288750..289994 1 NC_008253.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 289994 frsA 4190160 frsA Escherichia coli 536 fermentation/respiration switch protein YP_668203.1 288750 D 362663 CDS YP_668204.1 110640476 4190161 290052..290453 1 NC_008253.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 290453 4190161 ECP_0269 Escherichia coli 536 DNA-binding transcriptional regulator Crl YP_668204.1 290052 D 362663 CDS YP_668205.1 110640477 4190162 complement(290492..291547) 1 NC_008253.1 outer membrane phosphoporin protein E 291547 4190162 ECP_0270 Escherichia coli 536 outer membrane phosphoporin protein E YP_668205.1 290492 R 362663 CDS YP_668206.1 110640478 4190163 291836..292939 1 NC_008253.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 292939 4190163 ECP_0271 Escherichia coli 536 gamma-glutamyl kinase YP_668206.1 291836 D 362663 CDS YP_668207.1 110640479 4190164 292951..294204 1 NC_008253.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 294204 proA 4190164 proA Escherichia coli 536 gamma-glutamyl phosphate reductase YP_668207.1 292951 D 362663 CDS YP_668208.1 110640480 4190166 complement(294409..295569) 1 NC_008253.1 phage integrase 295569 4190166 ECP_0274 Escherichia coli 536 phage integrase YP_668208.1 294409 R 362663 CDS YP_668209.1 110640481 4190167 complement(295883..296227) 1 NC_008253.1 hypothetical protein 296227 4190167 ECP_0275 Escherichia coli 536 hypothetical protein YP_668209.1 295883 R 362663 CDS YP_668210.1 110640482 4190168 296525..297547 1 NC_008253.1 transposase for insertion sequence IS100 297547 4190168 ECP_0276 Escherichia coli 536 transposase for insertion sequence IS100 YP_668210.1 296525 D 362663 CDS YP_668211.1 110640483 4190169 297547..298326 1 NC_008253.1 transposase/IS protein 298326 4190169 ECP_0277 Escherichia coli 536 transposase/IS protein YP_668211.1 297547 D 362663 CDS YP_668212.1 110640484 4190170 complement(298377..300128) 1 NC_008253.1 hypothetical protein 300128 4190170 ECP_0278 Escherichia coli 536 hypothetical protein YP_668212.1 298377 R 362663 CDS YP_668213.1 110640485 4190171 complement(300321..300704) 1 NC_008253.1 transposase 300704 4190171 ECP_0279 Escherichia coli 536 transposase YP_668213.1 300321 R 362663 CDS YP_668214.1 110640486 4190172 301428..301625 1 NC_008253.1 hypothetical protein 301625 4190172 ECP_0280 Escherichia coli 536 hypothetical protein YP_668214.1 301428 D 362663 CDS YP_668215.1 110640487 4190173 301649..302683 1 NC_008253.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose-4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 302683 4190173 ECP_0281 Escherichia coli 536 phospho-2-dehydro-3-deoxyheptonate aldolase YP_668215.1 301649 D 362663 CDS YP_668216.1 110640488 4190174 302813..302992 1 NC_008253.1 hypothetical protein 302992 4190174 ECP_0282 Escherichia coli 536 hypothetical protein YP_668216.1 302813 D 362663 CDS YP_668217.1 110640489 4190175 complement(303560..304414) 1 NC_008253.1 transposase 304414 4190175 ECP_0283 Escherichia coli 536 transposase YP_668217.1 303560 R 362663 CDS YP_668218.1 110640490 4190176 complement(304411..304710) 1 NC_008253.1 transposase 304710 4190176 ECP_0284 Escherichia coli 536 transposase YP_668218.1 304411 R 362663 CDS YP_668219.1 110640491 4187528 304806..305861 1 NC_008253.1 ABC transporter ATP-binding protein 305861 4187528 ECP_0285 Escherichia coli 536 ABC transporter ATP-binding protein YP_668219.1 304806 D 362663 CDS YP_668220.1 110640492 4187529 306132..306464 1 NC_008253.1 hypothetical protein 306464 4187529 ECP_0286 Escherichia coli 536 hypothetical protein YP_668220.1 306132 D 362663 CDS YP_668221.1 110640493 4187530 complement(306641..307327) 1 NC_008253.1 hypothetical protein 307327 4187530 ECP_0287 Escherichia coli 536 hypothetical protein YP_668221.1 306641 R 362663 CDS YP_668222.1 110640494 4187531 complement(307422..307892) 1 NC_008253.1 hypothetical protein 307892 4187531 ECP_0288 Escherichia coli 536 hypothetical protein YP_668222.1 307422 R 362663 CDS YP_668223.1 110640495 4187532 308401..308850 1 NC_008253.1 hypothetical protein 308850 4187532 ECP_0289 Escherichia coli 536 hypothetical protein YP_668223.1 308401 D 362663 CDS YP_668224.1 110640496 4187533 309092..309661 1 NC_008253.1 hypothetical protein 309661 4187533 ECP_0290 Escherichia coli 536 hypothetical protein YP_668224.1 309092 D 362663 CDS YP_668225.1 110640497 4187534 complement(309936..310157) 1 NC_008253.1 fimbrial transcription regulator protein FaeA 310157 4187534 ECP_0291 Escherichia coli 536 fimbrial transcription regulator protein FaeA YP_668225.1 309936 R 362663 CDS YP_668226.1 110640498 4187535 310576..310905 1 NC_008253.1 major pilu subunit operon regulatory protein PapB 310905 4187535 ECP_0292 Escherichia coli 536 major pilu subunit operon regulatory protein PapB YP_668226.1 310576 D 362663 CDS YP_668227.1 110640499 4187536 311279..311824 1 NC_008253.1 S-fimbrial protein subunit 311824 4187536 ECP_0293 Escherichia coli 536 S-fimbrial protein subunit YP_668227.1 311279 D 362663 CDS YP_668228.1 110640500 4187537 311895..312434 1 NC_008253.1 minor F1C fimbrial subunit 312434 4187537 ECP_0294 Escherichia coli 536 minor F1C fimbrial subunit YP_668228.1 311895 D 362663 CDS YP_668229.1 110640501 4187538 312475..313170 1 NC_008253.1 F1C periplasmic chaperone 313170 4187538 ECP_0295 Escherichia coli 536 F1C periplasmic chaperone YP_668229.1 312475 D 362663 CDS YP_668230.1 110640502 4187539 313241..315871 1 NC_008253.1 F1C fimbrial usher 315871 4187539 ECP_0296 Escherichia coli 536 F1C fimbrial usher YP_668230.1 313241 D 362663 CDS YP_668231.1 110640503 4187540 315887..316411 1 NC_008253.1 F1C minor fimbrial subunit F 316411 4187540 ECP_0297 Escherichia coli 536 F1C minor fimbrial subunit F YP_668231.1 315887 D 362663 CDS YP_668232.1 110640504 4187541 316433..316924 1 NC_008253.1 F1C minor fimbrial subunit protein G presursor 316924 4187541 ECP_0298 Escherichia coli 536 F1C minor fimbrial subunit protein G presursor YP_668232.1 316433 D 362663 CDS YP_668233.1 110640505 4187542 316986..317885 1 NC_008253.1 F1C fimbrial adhesin 317885 4187542 ECP_0299 Escherichia coli 536 F1C fimbrial adhesin YP_668233.1 316986 D 362663 CDS YP_668234.1 110640506 4187543 318189..318929 1 NC_008253.1 hypothetical protein 318929 4187543 ECP_0300 Escherichia coli 536 hypothetical protein YP_668234.1 318189 D 362663 CDS YP_668235.1 110640507 4187544 319076..319627 1 NC_008253.1 MarR family transcriptional regulator 319627 4187544 ECP_0301 Escherichia coli 536 MarR family transcriptional regulator YP_668235.1 319076 D 362663 CDS YP_668236.1 110640508 4187545 320121..322298 1 NC_008253.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 322298 4187545 ECP_0302 Escherichia coli 536 outer membrane receptor FepA YP_668236.1 320121 D 362663 CDS YP_668237.1 110640509 4187546 complement(322343..323299) 1 NC_008253.1 IroE protein 323299 4187546 ECP_0303 Escherichia coli 536 IroE protein YP_668237.1 322343 R 362663 CDS YP_668238.1 110640510 4190518 complement(323384..324613) 1 NC_008253.1 esterase 324613 4190518 ECP_0304 Escherichia coli 536 esterase YP_668238.1 323384 R 362663 CDS YP_668239.1 110640511 4190519 complement(324717..328454) 1 NC_008253.1 ABC transporter 328454 4190519 ECP_0305 Escherichia coli 536 ABC transporter YP_668239.1 324717 R 362663 CDS YP_668240.1 110640512 4190520 complement(328516..329631) 1 NC_008253.1 glycosyl transferase family protein 329631 4190520 ECP_0306 Escherichia coli 536 glycosyl transferase family protein YP_668240.1 328516 R 362663 CDS YP_668241.1 110640513 4190521 330169..330468 1 NC_008253.1 hypothetical protein 330468 4190521 ECP_0307 Escherichia coli 536 hypothetical protein YP_668241.1 330169 D 362663 CDS YP_668242.1 110640514 4190522 complement(330479..330838) 1 NC_008253.1 transposase InsG for insertion sequence element IS4 330838 4190522 ECP_0308 Escherichia coli 536 transposase InsG for insertion sequence element IS4 YP_668242.1 330479 R 362663 CDS YP_668243.1 110640515 4190523 331753..332031 1 NC_008253.1 hypothetical protein 332031 4190523 ECP_0309 Escherichia coli 536 hypothetical protein YP_668243.1 331753 D 362663 CDS YP_668244.1 110640516 4190525 complement(332752..333210) 1 NC_008253.1 transposase 333210 4190525 ECP_0311 Escherichia coli 536 transposase YP_668244.1 332752 R 362663 CDS YP_668245.1 110640517 4190526 complement(333222..334031) 1 NC_008253.1 hypothetical protein 334031 4190526 ECP_0312 Escherichia coli 536 hypothetical protein YP_668245.1 333222 R 362663 CDS YP_668246.1 110640518 4190527 334157..334375 1 NC_008253.1 hypothetical protein 334375 4190527 ECP_0313 Escherichia coli 536 hypothetical protein YP_668246.1 334157 D 362663 CDS YP_668247.1 110640519 4190528 334467..336431 1 NC_008253.1 TonB-dependent receptor 336431 4190528 ECP_0314 Escherichia coli 536 TonB-dependent receptor YP_668247.1 334467 D 362663 CDS YP_668248.1 110640520 4190529 336450..337241 1 NC_008253.1 hypothetical protein 337241 4190529 ECP_0315 Escherichia coli 536 hypothetical protein YP_668248.1 336450 D 362663 CDS YP_668249.1 110640521 4190530 337442..338704 1 NC_008253.1 cobalamin synthesis protein 338704 4190530 ECP_0316 Escherichia coli 536 cobalamin synthesis protein YP_668249.1 337442 D 362663 CDS YP_668250.1 110640522 4190531 338889..339026 1 NC_008253.1 hypothetical protein 339026 4190531 ECP_0317 Escherichia coli 536 hypothetical protein YP_668250.1 338889 D 362663 CDS YP_668251.1 110640523 4190532 339159..339758 1 NC_008253.1 transposase for insertion sequence IS100 339758 4190532 ECP_0318 Escherichia coli 536 transposase for insertion sequence IS100 YP_668251.1 339159 D 362663 CDS YP_668252.1 110640524 4190533 339758..340537 1 NC_008253.1 transposase/IS protein 340537 4190533 ECP_0319 Escherichia coli 536 transposase/IS protein YP_668252.1 339758 D 362663 CDS YP_668253.1 110640525 4190534 complement(340588..341205) 1 NC_008253.1 IS orf 341205 4190534 ECP_0320 Escherichia coli 536 IS orf YP_668253.1 340588 R 362663 CDS YP_668254.1 110640526 4190535 complement(341225..341572) 1 NC_008253.1 transposase 341572 4190535 ECP_0321 Escherichia coli 536 transposase YP_668254.1 341225 R 362663 CDS YP_668255.1 110640527 4190536 complement(341569..341931) 1 NC_008253.1 IS orf 341931 4190536 ECP_0322 Escherichia coli 536 IS orf YP_668255.1 341569 R 362663 CDS YP_668256.1 110640528 4187983 complement(342066..342251) 1 NC_008253.1 hypothetical protein 342251 4187983 ECP_0323 Escherichia coli 536 hypothetical protein YP_668256.1 342066 R 362663 CDS YP_668257.1 110640529 4187984 complement(342718..343605) 1 NC_008253.1 specific inhibitor of chromosomal initiation of replication in vitro; inds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 343605 4187984 ECP_0324 Escherichia coli 536 chromosome replication initiation inhibitor protein YP_668257.1 342718 R 362663 CDS YP_668258.1 110640530 4187985 complement(343652..345148) 1 NC_008253.1 lysyl-tRNA synthetase 345148 4187985 ECP_0325 Escherichia coli 536 lysyl-tRNA synthetase YP_668258.1 343652 R 362663 CDS YP_668259.1 110640531 4187986 complement(345442..346164) 1 NC_008253.1 AraC family transcriptional regulator 346164 4187986 ECP_0326 Escherichia coli 536 AraC family transcriptional regulator YP_668259.1 345442 R 362663 CDS YP_668260.1 110640532 4187987 complement(346356..348482) 1 NC_008253.1 lysine decarboxylase 348482 4187987 ECP_0327 Escherichia coli 536 lysine decarboxylase YP_668260.1 346356 R 362663 CDS YP_668261.1 110640533 4187988 complement(348513..349823) 1 NC_008253.1 probable cadaverine/lysine antiporter; antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 349823 cadB 4187988 cadB Escherichia coli 536 lysine/cadaverine antiporter YP_668261.1 348513 R 362663 CDS YP_668262.1 110640534 4187989 350210..350572 1 NC_008253.1 IS orf 350572 4187989 ECP_0329 Escherichia coli 536 IS orf YP_668262.1 350210 D 362663 CDS YP_668263.1 110640535 4187990 complement(350873..351055) 1 NC_008253.1 hypothetical protein 351055 4187990 ECP_0330 Escherichia coli 536 hypothetical protein YP_668263.1 350873 R 362663 CDS YP_668264.1 110640536 4187991 351386..352258 1 NC_008253.1 hypothetical protein 352258 4187991 ECP_0331 Escherichia coli 536 hypothetical protein YP_668264.1 351386 D 362663 CDS YP_668265.1 110640537 4187992 352586..355714 1 NC_008253.1 autotransporter 355714 4187992 ECP_0332 Escherichia coli 536 autotransporter YP_668265.1 352586 D 362663 CDS YP_668266.1 110640538 4187993 356041..356859 1 NC_008253.1 hypothetical protein 356859 4187993 ECP_0333 Escherichia coli 536 hypothetical protein YP_668266.1 356041 D 362663 CDS YP_668267.1 110640539 4187994 356951..357436 1 NC_008253.1 anti-restriction protein 357436 4187994 ECP_0334 Escherichia coli 536 anti-restriction protein YP_668267.1 356951 D 362663 CDS YP_668268.1 110640540 4187995 357452..357928 1 NC_008253.1 RadC-like DNA repair protein 357928 4187995 ECP_0335 Escherichia coli 536 RadC-like DNA repair protein YP_668268.1 357452 D 362663 CDS YP_668269.1 110640541 4187996 357997..358218 1 NC_008253.1 hypothetical protein 358218 4187996 ECP_0336 Escherichia coli 536 hypothetical protein YP_668269.1 357997 D 362663 CDS YP_668270.1 110640542 4187997 358381..358749 1 NC_008253.1 hypothetical protein 358749 4187997 ECP_0337 Escherichia coli 536 hypothetical protein YP_668270.1 358381 D 362663 CDS YP_668271.1 110640543 4187998 358839..359216 1 NC_008253.1 hypothetical protein 359216 4187998 ECP_0338 Escherichia coli 536 hypothetical protein YP_668271.1 358839 D 362663 CDS YP_668272.1 110640544 4187999 359213..359701 1 NC_008253.1 hypothetical protein 359701 4187999 ECP_0339 Escherichia coli 536 hypothetical protein YP_668272.1 359213 D 362663 CDS YP_668273.1 110640545 4188000 359668..359910 1 NC_008253.1 hypothetical protein 359910 4188000 ECP_0340 Escherichia coli 536 hypothetical protein YP_668273.1 359668 D 362663 CDS YP_668274.1 110640546 4188001 360025..360849 1 NC_008253.1 hypothetical protein 360849 4188001 ECP_0341 Escherichia coli 536 hypothetical protein YP_668274.1 360025 D 362663 CDS YP_668275.1 110640547 4190693 complement(360942..362261) 1 NC_008253.1 phage integrase 362261 4190693 ECP_0342 Escherichia coli 536 phage integrase YP_668275.1 360942 R 362663 CDS YP_668276.1 110640548 4190694 362627..362965 1 NC_008253.1 CP4-like integrase 362965 4190694 ECP_0343 Escherichia coli 536 CP4-like integrase YP_668276.1 362627 D 362663 CDS YP_668277.1 110640549 4190695 complement(363400..363924) 1 NC_008253.1 MarR family transcriptional regulator 363924 4190695 ECP_0344 Escherichia coli 536 MarR family transcriptional regulator YP_668277.1 363400 R 362663 CDS YP_668278.1 110640550 4190696 complement(364050..368180) 1 NC_008253.1 extracellular serine protease of the IgA1 protease, secreted by a C-terminal autotransporter domain; protein SepA 368180 4190696 ECP_0345 Escherichia coli 536 protein SepA YP_668278.1 364050 R 362663 CDS YP_668279.1 110640551 4190697 complement(368508..368711) 1 NC_008253.1 hypothetical protein 368711 4190697 ECP_0346 Escherichia coli 536 hypothetical protein YP_668279.1 368508 R 362663 CDS YP_668280.1 110640552 4190698 368773..368988 1 NC_008253.1 insertion element IS1 1/2/3/5/6 protein InsA 368988 4190698 ECP_0347 Escherichia coli 536 insertion element IS1 1/2/3/5/6 protein InsA YP_668280.1 368773 D 362663 CDS YP_668281.1 110640553 4190699 369290..369466 1 NC_008253.1 InsB protein 369466 4190699 ECP_0348 Escherichia coli 536 InsB protein YP_668281.1 369290 D 362663 CDS YP_668282.1 110640554 4190700 369890..370075 1 NC_008253.1 hypothetical protein 370075 4190700 ECP_0349 Escherichia coli 536 hypothetical protein YP_668282.1 369890 D 362663 CDS YP_668283.1 110640555 4190701 370290..370904 1 NC_008253.1 integral membrane protein 370904 4190701 ECP_0350 Escherichia coli 536 integral membrane protein YP_668283.1 370290 D 362663 CDS YP_668284.1 110640556 4190702 complement(371153..371482) 1 NC_008253.1 ferredoxin 371482 4190702 ECP_0351 Escherichia coli 536 ferredoxin YP_668284.1 371153 R 362663 CDS YP_668285.1 110640557 4190703 complement(371789..372499) 1 NC_008253.1 hypothetical protein 372499 4190703 ECP_0352 Escherichia coli 536 hypothetical protein YP_668285.1 371789 R 362663 CDS YP_668286.1 110640558 4190704 complement(372468..374111) 1 NC_008253.1 hypothetical protein 374111 4190704 ECP_0353 Escherichia coli 536 hypothetical protein YP_668286.1 372468 R 362663 CDS YP_668287.1 110640559 4190705 complement(374101..376626) 1 NC_008253.1 hypothetical protein 376626 4190705 ECP_0354 Escherichia coli 536 hypothetical protein YP_668287.1 374101 R 362663 CDS YP_668288.1 110640560 4190706 complement(376652..377368) 1 NC_008253.1 hypothetical protein 377368 4190706 ECP_0355 Escherichia coli 536 hypothetical protein YP_668288.1 376652 R 362663 CDS YP_668289.1 110640561 4190707 complement(377377..377964) 1 NC_008253.1 hypothetical protein 377964 4190707 ECP_0356 Escherichia coli 536 hypothetical protein YP_668289.1 377377 R 362663 CDS YP_668290.1 110640562 4190708 complement(378039..378581) 1 NC_008253.1 hypothetical protein 378581 4190708 ECP_0357 Escherichia coli 536 hypothetical protein YP_668290.1 378039 R 362663 CDS YP_668291.1 110640563 4190709 379053..379343 1 NC_008253.1 hypothetical protein 379343 4190709 ECP_0358 Escherichia coli 536 hypothetical protein YP_668291.1 379053 D 362663 CDS YP_668292.1 110640564 4190710 complement(379665..379805) 1 NC_008253.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 379805 rpmJ 4190710 rpmJ Escherichia coli 536 50S ribosomal protein L36 YP_668292.1 379665 R 362663 CDS YP_668293.1 110640565 4190711 complement(379805..380071) 1 NC_008253.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 380071 rpmE2 4190711 rpmE2 Escherichia coli 536 50S ribosomal protein L31 YP_668293.1 379805 R 362663 CDS YP_668294.1 110640566 4190712 complement(381007..382149) 1 NC_008253.1 NADH-dependent flavin oxidoreductase 382149 4190712 ECP_0361 Escherichia coli 536 NADH-dependent flavin oxidoreductase YP_668294.1 381007 R 362663 CDS YP_668295.1 110640567 4191131 complement(382321..383241) 1 NC_008253.1 hypothetical protein 383241 4191131 ECP_0362 Escherichia coli 536 hypothetical protein YP_668295.1 382321 R 362663 CDS YP_668296.1 110640568 4191132 383398..384324 1 NC_008253.1 LysR family transcriptional regulator 384324 4191132 ECP_0363 Escherichia coli 536 LysR family transcriptional regulator YP_668296.1 383398 D 362663 CDS YP_668297.1 110640569 4191133 384524..385417 1 NC_008253.1 LysR family transcriptional regulator 385417 4191133 ECP_0364 Escherichia coli 536 LysR family transcriptional regulator YP_668297.1 384524 D 362663 CDS YP_668298.1 110640570 4191134 complement(385448..386437) 1 NC_008253.1 aldo/keto reductase 386437 4191134 ECP_0365 Escherichia coli 536 aldo/keto reductase YP_668298.1 385448 R 362663 CDS YP_668299.1 110640571 4191135 complement(386464..387315) 1 NC_008253.1 aldo/keto reductase 387315 4191135 ECP_0366 Escherichia coli 536 aldo/keto reductase YP_668299.1 386464 R 362663 CDS YP_668300.1 110640572 4191136 387881..392128 1 NC_008253.1 adhesin/invasin 392128 4191136 ECP_0367 Escherichia coli 536 adhesin/invasin YP_668300.1 387881 D 362663 CDS YP_668301.1 110640573 4191137 complement(392253..393110) 1 NC_008253.1 AraC family transcriptional regulator 393110 4191137 ECP_0368 Escherichia coli 536 AraC family transcriptional regulator YP_668301.1 392253 R 362663 CDS YP_668302.1 110640574 4191138 393358..394227 1 NC_008253.1 aldo/keto reductase 394227 4191138 ECP_0369 Escherichia coli 536 aldo/keto reductase YP_668302.1 393358 D 362663 CDS YP_668303.1 110640575 4191139 complement(394387..394980) 1 NC_008253.1 hypothetical protein 394980 4191139 ECP_0370 Escherichia coli 536 hypothetical protein YP_668303.1 394387 R 362663 CDS YP_668304.1 110640576 4191140 complement(394992..395228) 1 NC_008253.1 hypothetical protein 395228 4191140 ECP_0371 Escherichia coli 536 hypothetical protein YP_668304.1 394992 R 362663 CDS YP_668305.1 110640577 4191141 complement(395337..396662) 1 NC_008253.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 396662 4191141 ECP_0372 Escherichia coli 536 pyridine nucleotide-disulfide oxidoreductase YP_668305.1 395337 R 362663 CDS YP_668306.1 110640578 4191142 396889..397743 1 NC_008253.1 AraC family transcriptional regulator 397743 4191142 ECP_0373 Escherichia coli 536 AraC family transcriptional regulator YP_668306.1 396889 D 362663 CDS YP_668307.1 110640579 4191143 398270..398989 1 NC_008253.1 hypothetical protein 398989 4191143 ECP_0374 Escherichia coli 536 hypothetical protein YP_668307.1 398270 D 362663 CDS YP_668308.1 110640580 4191144 399000..400427 1 NC_008253.1 electron transport protein YkgF 400427 4191144 ECP_0375 Escherichia coli 536 electron transport protein YkgF YP_668308.1 399000 D 362663 CDS YP_668309.1 110640581 4191145 400420..401115 1 NC_008253.1 hypothetical protein 401115 4191145 ECP_0376 Escherichia coli 536 hypothetical protein YP_668309.1 400420 D 362663 CDS YP_668310.1 110640582 4191146 complement(401189..401386) 1 NC_008253.1 hypothetical protein 401386 4191146 ECP_0377 Escherichia coli 536 hypothetical protein YP_668310.1 401189 R 362663 CDS YP_668311.1 110640583 4191147 complement(401358..402026) 1 NC_008253.1 hypothetical protein 402026 4191147 ECP_0378 Escherichia coli 536 hypothetical protein YP_668311.1 401358 R 362663 CDS YP_668312.1 110640584 4191148 complement(402210..404507) 1 NC_008253.1 autotransporter 404507 4191148 ECP_0379 Escherichia coli 536 autotransporter YP_668312.1 402210 R 362663 CDS YP_668313.1 110640585 4191149 complement(404549..405310) 1 NC_008253.1 hypothetical protein 405310 4191149 ECP_0380 Escherichia coli 536 hypothetical protein YP_668313.1 404549 R 362663 CDS YP_668314.1 110640586 4191034 complement(405464..406258) 1 NC_008253.1 hypothetical protein 406258 4191034 ECP_0381 Escherichia coli 536 hypothetical protein YP_668314.1 405464 R 362663 CDS YP_668315.1 110640587 4191035 complement(406588..407151) 1 NC_008253.1 phage integrase 407151 4191035 ECP_0382 Escherichia coli 536 phage integrase YP_668315.1 406588 R 362663 CDS YP_668316.1 110640588 4191036 407041..407247 1 NC_008253.1 hypothetical protein 407247 4191036 ECP_0383 Escherichia coli 536 hypothetical protein YP_668316.1 407041 D 362663 CDS YP_668317.1 110640589 4191037 407257..407511 1 NC_008253.1 hypothetical protein 407511 4191037 ECP_0384 Escherichia coli 536 hypothetical protein YP_668317.1 407257 D 362663 CDS YP_668318.1 110640590 4191038 407967..408194 1 NC_008253.1 hypothetical protein 408194 4191038 ECP_0385 Escherichia coli 536 hypothetical protein YP_668318.1 407967 D 362663 CDS YP_668319.2 229560215 4191039 complement(408236..409906) 1 NC_008253.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 409906 4191039 ECP_0386 Escherichia coli 536 choline dehydrogenase YP_668319.2 408236 R 362663 CDS YP_668320.1 110640592 4191040 complement(409920..411392) 1 NC_008253.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 411392 4191040 ECP_0387 Escherichia coli 536 betaine aldehyde dehydrogenase YP_668320.1 409920 R 362663 CDS YP_668321.1 110640593 4191041 complement(411406..412011) 1 NC_008253.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 412011 4191041 ECP_0388 Escherichia coli 536 transcriptional regulator BetI YP_668321.1 411406 R 362663 CDS YP_668322.1 110640594 4191042 411910..412125 1 NC_008253.1 hypothetical protein 412125 4191042 ECP_0389 Escherichia coli 536 hypothetical protein YP_668322.1 411910 D 362663 CDS YP_668323.1 110640595 4191043 412122..414155 1 NC_008253.1 proton-motive-force-driven choline transporter; choline transport protein BetT 414155 4191043 ECP_0390 Escherichia coli 536 choline transport protein BetT YP_668323.1 412122 D 362663 CDS YP_668324.1 110640596 4191044 415031..416119 1 NC_008253.1 hypothetical protein 416119 4191044 ECP_0391 Escherichia coli 536 hypothetical protein YP_668324.1 415031 D 362663 CDS YP_668325.1 110640597 4191045 complement(416161..417093) 1 NC_008253.1 transcriptional regulator YahB 417093 4191045 ECP_0392 Escherichia coli 536 transcriptional regulator YahB YP_668325.1 416161 R 362663 CDS YP_668326.1 110640598 4191046 complement(417185..417682) 1 NC_008253.1 hypothetical protein 417682 4191046 ECP_0393 Escherichia coli 536 hypothetical protein YP_668326.1 417185 R 362663 CDS YP_668327.1 110640599 4191047 417759..418001 1 NC_008253.1 hypothetical protein 418001 4191047 ECP_0394 Escherichia coli 536 hypothetical protein YP_668327.1 417759 D 362663 CDS YP_668328.1 110640600 4191048 417940..418545 1 NC_008253.1 ankyrin repeat-containing protein 418545 4191048 ECP_0395 Escherichia coli 536 ankyrin repeat-containing protein YP_668328.1 417940 D 362663 CDS YP_668329.1 110640601 4191049 418585..419448 1 NC_008253.1 hypothetical protein 419448 4191049 ECP_0396 Escherichia coli 536 hypothetical protein YP_668329.1 418585 D 362663 CDS YP_668330.1 110640602 4191050 419438..420985 1 NC_008253.1 YahF/FdrA-like protein 420985 4191050 ECP_0397 Escherichia coli 536 YahF/FdrA-like protein YP_668330.1 419438 D 362663 CDS YP_668331.1 110640603 4191051 420985..422403 1 NC_008253.1 hypothetical protein 422403 4191051 ECP_0398 Escherichia coli 536 hypothetical protein YP_668331.1 420985 D 362663 CDS YP_668332.1 110640604 4191052 422650..423600 1 NC_008253.1 carbamate kinase 423600 4191052 ECP_0399 Escherichia coli 536 carbamate kinase YP_668332.1 422650 D 362663 CDS YP_668333.1 110640605 4191053 423610..424992 1 NC_008253.1 deaminase 424992 4191053 ECP_0400 Escherichia coli 536 deaminase YP_668333.1 423610 D 362663 CDS YP_668334.1 110640606 4191762 425369..426418 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YahK 426418 4191762 ECP_0401 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YahK YP_668334.1 425369 D 362663 CDS YP_668335.1 110640607 4191763 426652..426816 1 NC_008253.1 hypothetical protein 426816 4191763 ECP_0402 Escherichia coli 536 hypothetical protein YP_668335.1 426652 D 362663 CDS YP_668336.1 110640608 4191765 complement(427300..427974) 1 NC_008253.1 LysE family translocator 427974 4191765 ECP_0404 Escherichia coli 536 LysE family translocator YP_668336.1 427300 R 362663 CDS YP_668337.1 110640609 4191766 428121..428396 1 NC_008253.1 hypothetical protein 428396 4191766 ECP_0405 Escherichia coli 536 hypothetical protein YP_668337.1 428121 D 362663 CDS YP_668338.1 110640610 4191767 complement(428497..430083) 1 NC_008253.1 propionate catabolism operon regulatory protein 430083 4191767 ECP_0406 Escherichia coli 536 propionate catabolism operon regulatory protein YP_668338.1 428497 R 362663 CDS YP_668339.1 110640611 4191768 430322..431212 1 NC_008253.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 431212 prpB 4191768 prpB Escherichia coli 536 2-methylisocitrate lyase YP_668339.1 430322 D 362663 CDS YP_668340.1 110640612 4191769 431372..432541 1 NC_008253.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 432541 4191769 ECP_0408 Escherichia coli 536 methylcitrate synthase YP_668340.1 431372 D 362663 CDS YP_668341.1 110640613 4191770 432575..434026 1 NC_008253.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 434026 prpD 4191770 prpD Escherichia coli 536 2-methylcitrate dehydratase YP_668341.1 432575 D 362663 CDS YP_668342.1 110640614 4191771 434066..435952 1 NC_008253.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 435952 prpE 4191771 prpE Escherichia coli 536 propionyl-CoA synthetase YP_668342.1 434066 D 362663 CDS YP_668343.1 110640615 4191772 436277..437536 1 NC_008253.1 cytosine permease 437536 codB 4191772 codB Escherichia coli 536 cytosine permease YP_668343.1 436277 D 362663 CDS YP_668344.1 110640616 4191773 437526..438809 1 NC_008253.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 438809 4191773 ECP_0412 Escherichia coli 536 cytosine deaminase YP_668344.1 437526 D 362663 CDS YP_668345.1 110640617 4191774 complement(438889..439491) 1 NC_008253.1 IS transposase 439491 4191774 ECP_0413 Escherichia coli 536 IS transposase YP_668345.1 438889 R 362663 CDS YP_668346.1 110640618 4191775 complement(439716..440237) 1 NC_008253.1 IS transposase 440237 4191775 ECP_0414 Escherichia coli 536 IS transposase YP_668346.1 439716 R 362663 CDS YP_668347.1 110640619 4191776 complement(440366..440986) 1 NC_008253.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 440986 lacA 4191776 lacA Escherichia coli 536 galactoside O-acetyltransferase YP_668347.1 440366 R 362663 CDS YP_668348.1 110640620 4191777 complement(441043..442296) 1 NC_008253.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 442296 lacY 4191777 lacY Escherichia coli 536 galactoside permease YP_668348.1 441043 R 362663 CDS YP_668349.1 110640621 4191778 complement(442348..445422) 1 NC_008253.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 445422 lacZ 4191778 lacZ Escherichia coli 536 beta-D-galactosidase YP_668349.1 442348 R 362663 CDS YP_668350.1 110640622 4191779 complement(445545..446627) 1 NC_008253.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 446627 lacI 4191779 lacI Escherichia coli 536 lac repressor YP_668350.1 445545 R 362663 CDS YP_668351.1 110640623 4188789 446829..447368 1 NC_008253.1 hypothetical protein 447368 4188789 ECP_0419 Escherichia coli 536 hypothetical protein YP_668351.1 446829 D 362663 CDS YP_668352.1 110640624 4188790 complement(447595..448428) 1 NC_008253.1 esterase 448428 4188790 ECP_0420 Escherichia coli 536 esterase YP_668352.1 447595 R 362663 CDS YP_668353.1 110640625 4188791 complement(448521..449630) 1 NC_008253.1 glutathione-dependent formaldehyde dehydrogenase 449630 4188791 ECP_0421 Escherichia coli 536 glutathione-dependent formaldehyde dehydrogenase YP_668353.1 448521 R 362663 CDS YP_668354.1 110640626 4188792 complement(449665..449940) 1 NC_008253.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 449940 4188792 ECP_0422 Escherichia coli 536 regulator protein FrmR YP_668354.1 449665 R 362663 CDS YP_668355.1 110640627 4188793 complement(450130..450903) 1 NC_008253.1 hypothetical protein 450903 4188793 ECP_0423 Escherichia coli 536 hypothetical protein YP_668355.1 450130 R 362663 CDS YP_668356.1 110640628 4188794 complement(450905..451345) 1 NC_008253.1 transferase 451345 4188794 ECP_0424 Escherichia coli 536 transferase YP_668356.1 450905 R 362663 CDS YP_668357.1 110640629 4188795 complement(451464..452660) 1 NC_008253.1 glycosyl transferase family protein 452660 4188795 ECP_0425 Escherichia coli 536 glycosyl transferase family protein YP_668357.1 451464 R 362663 CDS YP_668358.1 110640630 4188796 complement(452670..453341) 1 NC_008253.1 LmbE-like protein 453341 4188796 ECP_0426 Escherichia coli 536 LmbE-like protein YP_668358.1 452670 R 362663 CDS YP_668359.1 110640631 4188799 454925..455692 1 NC_008253.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 455692 tauB 4188799 tauB Escherichia coli 536 taurine transporter ATP-binding subunit YP_668359.1 454925 D 362663 CDS YP_668360.1 110640632 4188800 455689..456516 1 NC_008253.1 taurine transporter subunit 456516 4188800 ECP_0430 Escherichia coli 536 taurine transporter subunit YP_668360.1 455689 D 362663 CDS YP_668361.1 110640633 4188801 456513..457364 1 NC_008253.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 457364 tauD 4188801 tauD Escherichia coli 536 taurine dioxygenase YP_668361.1 456513 D 362663 CDS YP_668362.1 110640634 4188802 complement(457404..458411) 1 NC_008253.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 458411 4188802 ECP_0432 Escherichia coli 536 delta-aminolevulinic acid dehydratase YP_668362.1 457404 R 362663 CDS YP_668363.1 110640635 4188803 458904..461891 1 NC_008253.1 autotransporter/pertactin 461891 4188803 ECP_0433 Escherichia coli 536 autotransporter/pertactin YP_668363.1 458904 D 362663 CDS YP_668364.1 110640636 4188804 461977..462600 1 NC_008253.1 DNA-binding transcriptional regulator 462600 4188804 ECP_0434 Escherichia coli 536 DNA-binding transcriptional regulator YP_668364.1 461977 D 362663 CDS YP_668365.1 110640637 4188805 complement(462601..463731) 1 NC_008253.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 463731 4188805 ECP_0435 Escherichia coli 536 beta-lactam binding protein AmpH YP_668365.1 462601 R 362663 CDS YP_668366.1 110640638 4188204 464110..465330 1 NC_008253.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 465330 4188204 ECP_0436 Escherichia coli 536 transporter YP_668366.1 464110 D 362663 CDS YP_668367.1 110640639 4188205 465343..466437 1 NC_008253.1 lipoprotein YaiW 466437 4188205 ECP_0437 Escherichia coli 536 lipoprotein YaiW YP_668367.1 465343 D 362663 CDS YP_668368.1 110640640 4188206 complement(466496..466804) 1 NC_008253.1 hypothetical protein 466804 4188206 ECP_0438 Escherichia coli 536 hypothetical protein YP_668368.1 466496 R 362663 CDS YP_668369.1 110640641 4188207 467064..467276 1 NC_008253.1 hypothetical protein 467276 4188207 ECP_0439 Escherichia coli 536 hypothetical protein YP_668369.1 467064 D 362663 CDS YP_668370.1 110640642 4188208 complement(467300..468394) 1 NC_008253.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 468394 ddl 4188208 ddl Escherichia coli 536 D-alanyl-alanine synthetase A YP_668370.1 467300 R 362663 CDS YP_668371.1 110640643 4188209 468857..469117 1 NC_008253.1 hypothetical protein 469117 4188209 ECP_0441 Escherichia coli 536 hypothetical protein YP_668371.1 468857 D 362663 CDS YP_668372.1 110640644 4188210 469218..470633 1 NC_008253.1 alkaline phosphatase 470633 4188210 ECP_0442 Escherichia coli 536 alkaline phosphatase YP_668372.1 469218 D 362663 CDS YP_668373.1 110640645 4188211 470752..471072 1 NC_008253.1 hypothetical protein 471072 4188211 ECP_0443 Escherichia coli 536 hypothetical protein YP_668373.1 470752 D 362663 CDS YP_668374.1 110640646 4188212 471174..472289 1 NC_008253.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 472289 adrA 4188212 adrA Escherichia coli 536 diguanylate cyclase AdrA YP_668374.1 471174 D 362663 CDS YP_668375.1 110640647 4188213 complement(472306..473115) 1 NC_008253.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 473115 4188213 ECP_0445 Escherichia coli 536 pyrroline-5-carboxylate reductase YP_668375.1 472306 R 362663 CDS YP_668376.1 110640648 4188214 473235..473693 1 NC_008253.1 hypothetical protein 473693 4188214 ECP_0446 Escherichia coli 536 hypothetical protein YP_668376.1 473235 D 362663 CDS YP_668377.1 110640649 4188215 473876..474400 1 NC_008253.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 474400 aroL 4188215 aroL Escherichia coli 536 shikimate kinase YP_668377.1 473876 D 362663 CDS YP_668378.1 110640650 4188216 474450..474641 1 NC_008253.1 hypothetical protein 474641 4188216 ECP_0448 Escherichia coli 536 hypothetical protein YP_668378.1 474450 D 362663 CDS YP_668379.1 110640651 4188217 474672..474851 1 NC_008253.1 hypothetical protein 474851 4188217 ECP_0449 Escherichia coli 536 hypothetical protein YP_668379.1 474672 D 362663 CDS YP_668380.1 110640652 4188218 474899..475576 1 NC_008253.1 hypothetical protein 475576 4188218 ECP_0450 Escherichia coli 536 hypothetical protein YP_668380.1 474899 D 362663 CDS YP_668381.1 110640653 4188219 475648..475932 1 NC_008253.1 hypothetical protein 475932 4188219 ECP_0451 Escherichia coli 536 hypothetical protein YP_668381.1 475648 D 362663 CDS YP_668382.1 110640654 4188220 476140..476421 1 NC_008253.1 hypothetical protein 476421 4188220 ECP_0452 Escherichia coli 536 hypothetical protein YP_668382.1 476140 D 362663 CDS YP_668383.1 110640655 4188221 complement(476579..477490) 1 NC_008253.1 Required for efficient pilin antigenic variation; recombination associated protein 477490 rdgC 4188221 rdgC Escherichia coli 536 recombination associated protein YP_668383.1 476579 R 362663 CDS YP_668384.1 110640656 4188222 477615..478523 1 NC_008253.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 478523 4188222 ECP_0454 Escherichia coli 536 fructokinase YP_668384.1 477615 D 362663 CDS YP_668385.1 110640657 4188223 complement(478792..479976) 1 NC_008253.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 479976 4188223 ECP_0455 Escherichia coli 536 MFS transport protein AraJ YP_668385.1 478792 R 362663 CDS YP_668386.1 110640658 4188166 complement(480102..483245) 1 NC_008253.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC 483245 4188166 ECP_0456 Escherichia coli 536 exonuclease SbcC YP_668386.1 480102 R 362663 CDS YP_668387.1 110640659 4188167 complement(483242..484468) 1 NC_008253.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 484468 4188167 ECP_0457 Escherichia coli 536 exonuclease SbcD YP_668387.1 483242 R 362663 CDS YP_668388.1 110640660 4188168 484634..485365 1 NC_008253.1 phosphate regulon transcriptional regulatory protein PhoB 485365 4188168 ECP_0458 Escherichia coli 536 phosphate regulon transcriptional regulatory protein PhoB YP_668388.1 484634 D 362663 CDS YP_668389.1 110640661 4188169 485380..486675 1 NC_008253.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 486675 phoR 4188169 phoR Escherichia coli 536 phosphate regulon sensor protein YP_668389.1 485380 D 362663 CDS YP_668390.1 110640662 4188170 487082..488401 1 NC_008253.1 branched-chain amino acid permease 488401 4188170 ECP_0460 Escherichia coli 536 branched-chain amino acid permease YP_668390.1 487082 D 362663 CDS YP_668391.1 110640663 4188171 488477..489850 1 NC_008253.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 489850 proY 4188171 proY Escherichia coli 536 proline-specific permease YP_668391.1 488477 D 362663 CDS YP_668392.1 110640664 4188172 490006..491823 1 NC_008253.1 maltodextrin glucosidase 491823 4188172 ECP_0462 Escherichia coli 536 maltodextrin glucosidase YP_668392.1 490006 D 362663 CDS YP_668393.1 110640665 4188173 complement(491828..492409) 1 NC_008253.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase 492409 4188173 ECP_0463 Escherichia coli 536 ACP phosphodieterase YP_668393.1 491828 R 362663 CDS YP_668394.1 110640666 4188174 492502..493572 1 NC_008253.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 493572 queA 4188174 queA Escherichia coli 536 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_668394.1 492502 D 362663 CDS YP_668395.1 110640667 4188175 493627..494754 1 NC_008253.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 494754 tgt 4188175 tgt Escherichia coli 536 queuine tRNA-ribosyltransferase YP_668395.1 493627 D 362663 CDS YP_668396.1 110640668 4188176 494777..495109 1 NC_008253.1 preprotein translocase subunit; member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 495109 yajC 4188176 yajC Escherichia coli 536 preprotein translocase subunit YajC YP_668396.1 494777 D 362663 CDS YP_668397.1 110640669 4188177 495137..496984 1 NC_008253.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 496984 secD 4188177 secD Escherichia coli 536 preprotein translocase subunit SecD YP_668397.1 495137 D 362663 CDS YP_668398.1 110640670 4188178 496950..497966 1 NC_008253.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 497966 secF 4188178 secF Escherichia coli 536 preprotein translocase subunit SecF YP_668398.1 496950 D 362663 CDS YP_668399.1 110640671 4188179 498096..498443 1 NC_008253.1 hypothetical protein 498443 4188179 ECP_0469 Escherichia coli 536 hypothetical protein YP_668399.1 498096 D 362663 CDS YP_668400.1 110640672 4188180 complement(498481..499365) 1 NC_008253.1 nucleoside-specific channel-forming protein tsx 499365 4188180 ECP_0470 Escherichia coli 536 nucleoside-specific channel-forming protein tsx YP_668400.1 498481 R 362663 CDS YP_668401.1 110640673 4188181 complement(499664..500203) 1 NC_008253.1 hypothetical protein 500203 4188181 ECP_0471 Escherichia coli 536 hypothetical protein YP_668401.1 499664 R 362663 CDS YP_668402.1 110640674 4188182 500354..500803 1 NC_008253.1 transcriptional regulator NrdR 500803 nrdR 4188182 nrdR Escherichia coli 536 transcriptional regulator NrdR YP_668402.1 500354 D 362663 CDS YP_668403.1 110640675 4188183 500825..501910 1 NC_008253.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 501910 ribD 4188183 ribD Escherichia coli 536 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_668403.1 500825 D 362663 CDS YP_668404.1 110640676 4188184 501999..502469 1 NC_008253.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 502469 ribH 4188184 ribH Escherichia coli 536 6,7-dimethyl-8-ribityllumazine synthase YP_668404.1 501999 D 362663 CDS YP_668405.1 110640677 4189604 502489..502908 1 NC_008253.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 502908 nusB 4189604 nusB Escherichia coli 536 transcription antitermination protein NusB YP_668405.1 502489 D 362663 CDS YP_668406.1 110640678 4189605 502986..503963 1 NC_008253.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 503963 4189605 ECP_0476 Escherichia coli 536 thiamine monophosphate kinase YP_668406.1 502986 D 362663 CDS YP_668407.1 110640679 4189606 503941..504459 1 NC_008253.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 504459 4189606 ECP_0477 Escherichia coli 536 phosphatidylglycerophosphatase A YP_668407.1 503941 D 362663 CDS YP_668408.1 110640680 4189607 complement(504513..505487) 1 NC_008253.1 oxidoreductase 505487 4189607 ECP_0478 Escherichia coli 536 oxidoreductase YP_668408.1 504513 R 362663 CDS YP_668409.1 110640681 4189608 complement(505542..507404) 1 NC_008253.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 507404 4189608 ECP_0479 Escherichia coli 536 1-deoxy-D-xylulose-5-phosphate synthase YP_668409.1 505542 R 362663 CDS YP_668410.1 110640682 4189609 complement(507429..508328) 1 NC_008253.1 geranyltranstransferase 508328 4189609 ECP_0480 Escherichia coli 536 geranyltranstransferase YP_668410.1 507429 R 362663 CDS YP_668411.1 110640683 4189610 complement(508328..508570) 1 NC_008253.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 508570 4189610 ECP_0481 Escherichia coli 536 exodeoxyribonuclease VII small subunit YP_668411.1 508328 R 362663 CDS YP_668412.1 110640684 4189613 complement(510279..510719) 1 NC_008253.1 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis; ThiJ protein 510719 4189613 ECP_0484 Escherichia coli 536 ThiJ protein YP_668412.1 510279 R 362663 CDS YP_668413.1 110640685 4189614 complement(510832..511743) 1 NC_008253.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 511743 4189614 ECP_0485 Escherichia coli 536 2-dehydropantoate 2-reductase YP_668413.1 510832 R 362663 CDS YP_668414.1 110640686 4189615 511911..512402 1 NC_008253.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 512402 4189615 ECP_0486 Escherichia coli 536 nucleotide-binding protein YP_668414.1 511911 D 362663 CDS YP_668415.1 110640687 4189616 complement(512530..513894) 1 NC_008253.1 transporter 513894 4189616 ECP_0487 Escherichia coli 536 transporter YP_668415.1 512530 R 362663 CDS YP_668416.1 110640688 4189617 complement(514043..514933) 1 NC_008253.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 514933 4189617 ECP_0488 Escherichia coli 536 protoheme IX farnesyltransferase YP_668416.1 514043 R 362663 CDS YP_668417.1 110640689 4189618 complement(514945..515274) 1 NC_008253.1 cytochrome o ubiquinol oxidase subunit IV 515274 4189618 ECP_0489 Escherichia coli 536 cytochrome o ubiquinol oxidase subunit IV YP_668417.1 514945 R 362663 CDS YP_668418.1 110640690 4189619 complement(515274..515888) 1 NC_008253.1 cytochrome o ubiquinol oxidase subunit III 515888 4189619 ECP_0490 Escherichia coli 536 cytochrome o ubiquinol oxidase subunit III YP_668418.1 515274 R 362663 CDS YP_668419.1 110640691 4189620 complement(515878..517869) 1 NC_008253.1 cytochrome o ubiquinol oxidase subunit I 517869 4189620 ECP_0491 Escherichia coli 536 cytochrome o ubiquinol oxidase subunit I YP_668419.1 515878 R 362663 CDS YP_668420.1 110640692 4190041 complement(517891..518838) 1 NC_008253.1 cytochrome o ubiquinol oxidase subunit II 518838 4190041 ECP_0492 Escherichia coli 536 cytochrome o ubiquinol oxidase subunit II YP_668420.1 517891 R 362663 CDS YP_668421.1 110640693 4190042 complement(519298..520773) 1 NC_008253.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 520773 ampG 4190042 ampG Escherichia coli 536 muropeptide transporter YP_668421.1 519298 R 362663 CDS YP_668422.1 110640694 4190043 complement(520817..521497) 1 NC_008253.1 hypothetical protein 521497 4190043 ECP_0494 Escherichia coli 536 hypothetical protein YP_668422.1 520817 R 362663 CDS YP_668423.1 110640695 4190044 521700..522017 1 NC_008253.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 522017 4190044 ECP_0495 Escherichia coli 536 transcriptional regulator BolA YP_668423.1 521700 D 362663 CDS YP_668424.1 110640696 4190045 522026..522214 1 NC_008253.1 hypothetical protein 522214 4190045 ECP_0496 Escherichia coli 536 hypothetical protein YP_668424.1 522026 D 362663 CDS YP_668425.1 110640697 4190046 522361..523659 1 NC_008253.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 523659 tig 4190046 tig Escherichia coli 536 trigger factor YP_668425.1 522361 D 362663 CDS YP_668426.1 110640698 4190047 523905..524528 1 NC_008253.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 524528 clpP 4190047 clpP Escherichia coli 536 ATP-dependent Clp protease proteolytic subunit YP_668426.1 523905 D 362663 CDS YP_668427.1 110640699 4190048 524654..525928 1 NC_008253.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 525928 clpX 4190048 clpX Escherichia coli 536 ATP-dependent protease ATP-binding subunit ClpX YP_668427.1 524654 D 362663 CDS YP_668428.1 110640700 4190049 526116..528470 1 NC_008253.1 DNA-binding ATP-dependent protease La 528470 4190049 ECP_0500 Escherichia coli 536 DNA-binding ATP-dependent protease La YP_668428.1 526116 D 362663 CDS YP_668429.1 110640701 4190050 528679..528951 1 NC_008253.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 528951 4190050 ECP_0501 Escherichia coli 536 transcriptional regulator HU subunit beta YP_668429.1 528679 D 362663 CDS YP_668430.1 110640702 4190051 529143..531014 1 NC_008253.1 peptidyl-prolyl cis-trans isomerase 531014 4190051 ECP_0502 Escherichia coli 536 peptidyl-prolyl cis-trans isomerase YP_668430.1 529143 D 362663 CDS YP_668431.1 110640703 4190052 531165..531536 1 NC_008253.1 hypothetical protein 531536 4190052 ECP_0503 Escherichia coli 536 hypothetical protein YP_668431.1 531165 D 362663 CDS YP_668432.1 110640704 4190053 531642..532040 1 NC_008253.1 hypothetical protein 532040 4190053 ECP_0504 Escherichia coli 536 hypothetical protein YP_668432.1 531642 D 362663 CDS YP_668433.1 110640705 4190054 complement(532092..532787) 1 NC_008253.1 Queuosine biosynthesis protein queC; YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 532787 4190054 ECP_0505 Escherichia coli 536 queuosine biosynthesis protein QueC YP_668433.1 532092 R 362663 CDS YP_668434.1 110640706 4190055 complement(532852..534552) 1 NC_008253.1 hypothetical protein YbaE; extracellular solute-binding protein 534552 4190055 ECP_0506 Escherichia coli 536 extracellular solute-binding protein YP_668434.1 532852 R 362663 CDS YP_668435.1 110640707 4190056 534652..535470 1 NC_008253.1 haloacid dehalogenase-like hydrolase 535470 4190056 ECP_0507 Escherichia coli 536 haloacid dehalogenase-like hydrolase YP_668435.1 534652 D 362663 CDS YP_668436.1 110640708 4190057 535539..536081 1 NC_008253.1 AsnC family transcriptional regulator 536081 4190057 ECP_0508 Escherichia coli 536 AsnC family transcriptional regulator YP_668436.1 535539 D 362663 CDS YP_668437.1 110640709 4190058 536111..537883 1 NC_008253.1 multidrug transporter membrane\ATP-binding components 537883 4190058 ECP_0509 Escherichia coli 536 multidrug transporter membrane\ATP-binding components YP_668437.1 536111 D 362663 CDS YP_668438.1 110640710 4190059 537876..539657 1 NC_008253.1 multidrug transporter membrane\ATP-binding components 539657 4190059 ECP_0510 Escherichia coli 536 multidrug transporter membrane\ATP-binding components YP_668438.1 537876 D 362663 CDS YP_668439.1 110640711 4190060 539838..540176 1 NC_008253.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 540176 4190060 ECP_0511 Escherichia coli 536 nitrogen regulatory protein P-II 2 YP_668439.1 539838 D 362663 CDS YP_668440.1 110640712 4188113 540206..541492 1 NC_008253.1 ammonium transporter 541492 4188113 ECP_0512 Escherichia coli 536 ammonium transporter YP_668440.1 540206 D 362663 CDS YP_668441.1 110640713 4188114 complement(541541..542401) 1 NC_008253.1 acyl-CoA thioesterase 542401 4188114 ECP_0513 Escherichia coli 536 acyl-CoA thioesterase YP_668441.1 541541 R 362663 CDS YP_668442.1 110640714 4188115 542619..543053 1 NC_008253.1 similar to N-terminal part of lipoprotein YbaY; hypothetical protein 543053 4188115 ECP_0514 Escherichia coli 536 hypothetical protein YP_668442.1 542619 D 362663 CDS YP_668443.1 110640715 4188116 543070..543192 1 NC_008253.1 hypothetical protein 543192 4188116 ECP_0515 Escherichia coli 536 hypothetical protein YP_668443.1 543070 D 362663 CDS YP_668444.1 110640716 4188117 complement(543223..543534) 1 NC_008253.1 methyltransferase 543534 4188117 ECP_0516 Escherichia coli 536 methyltransferase YP_668444.1 543223 R 362663 CDS YP_668445.1 110640717 4188118 543913..544266 1 NC_008253.1 hypothetical protein 544266 4188118 ECP_0517 Escherichia coli 536 hypothetical protein YP_668445.1 543913 D 362663 CDS YP_668446.1 110640718 4188119 complement(544308..545858) 1 NC_008253.1 hypothetical protein YlaB; diguanylate phosphodiesterase 545858 4188119 ECP_0518 Escherichia coli 536 diguanylate phosphodiesterase YP_668446.1 544308 R 362663 CDS YP_668447.1 110640719 4188120 complement(546022..546492) 1 NC_008253.1 hypothetical protein 546492 4188120 ECP_0519 Escherichia coli 536 hypothetical protein YP_668447.1 546022 R 362663 CDS YP_668448.1 110640720 4188121 complement(546608..547159) 1 NC_008253.1 maltose O-acetyltransferase 547159 4188121 ECP_0520 Escherichia coli 536 maltose O-acetyltransferase YP_668448.1 546608 R 362663 CDS YP_668449.1 110640721 4188122 complement(547333..547551) 1 NC_008253.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 547551 4188122 ECP_0521 Escherichia coli 536 hemolysin expression-modulating protein YP_668449.1 547333 R 362663 CDS YP_668450.1 110640722 4188123 complement(547577..547951) 1 NC_008253.1 hypothetical protein 547951 4188123 ECP_0522 Escherichia coli 536 hypothetical protein YP_668450.1 547577 R 362663 CDS YP_668451.1 110640723 4188124 complement(548496..551645) 1 NC_008253.1 acriflavine resistance protein B 551645 4188124 ECP_0523 Escherichia coli 536 acriflavine resistance protein B YP_668451.1 548496 R 362663 CDS YP_668452.1 110640724 4188125 complement(551668..552492) 1 NC_008253.1 acriflavin resistance protein A 552492 4188125 ECP_0524 Escherichia coli 536 acriflavin resistance protein A YP_668452.1 551668 R 362663 CDS YP_668453.1 110640725 4188126 553056..553649 1 NC_008253.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 553649 4188126 ECP_0525 Escherichia coli 536 DNA-binding transcriptional repressor AcrR YP_668453.1 553056 D 362663 CDS YP_668454.1 110640726 4188127 553777..557139 1 NC_008253.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 557139 4188127 ECP_0526 Escherichia coli 536 potassium efflux protein KefA YP_668454.1 553777 D 362663 CDS YP_668455.1 110640727 4188128 complement(557351..557512) 1 NC_008253.1 hypothetical protein 557512 4188128 ECP_0527 Escherichia coli 536 hypothetical protein YP_668455.1 557351 R 362663 CDS YP_668456.1 110640728 4188129 complement(557526..558053) 1 NC_008253.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 558053 4188129 ECP_0528 Escherichia coli 536 primosomal replication protein N'' YP_668456.1 557526 R 362663 CDS YP_668457.1 110640729 4188130 558123..558500 1 NC_008253.1 hypothetical protein 558500 4188130 ECP_0529 Escherichia coli 536 hypothetical protein YP_668457.1 558123 D 362663 CDS YP_668458.1 110640730 4188131 558653..559204 1 NC_008253.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 559204 4188131 ECP_0530 Escherichia coli 536 adenine phosphoribosyltransferase YP_668458.1 558653 D 362663 CDS YP_668459.1 110640731 4189238 559333..561264 1 NC_008253.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 561264 4189238 ECP_0531 Escherichia coli 536 DNA polymerase III subunits gamma and tau YP_668459.1 559333 D 362663 CDS YP_668460.1 110640732 4189239 561317..561646 1 NC_008253.1 hypothetical protein 561646 4189239 ECP_0532 Escherichia coli 536 hypothetical protein YP_668460.1 561317 D 362663 CDS YP_668461.1 110640733 4189240 561646..562251 1 NC_008253.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 562251 recR 4189240 recR Escherichia coli 536 recombination protein RecR YP_668461.1 561646 D 362663 CDS YP_668462.1 110640734 4189241 562361..564235 1 NC_008253.1 molecular chaperone; heat shock protein 90 564235 4189241 ECP_0534 Escherichia coli 536 heat shock protein 90 YP_668462.1 562361 D 362663 CDS YP_668463.1 110640735 4189242 564416..565060 1 NC_008253.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 565060 adk 4189242 adk Escherichia coli 536 adenylate kinase YP_668463.1 564416 D 362663 CDS YP_668464.1 110640736 4189243 565192..566154 1 NC_008253.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 566154 hemH 4189243 hemH Escherichia coli 536 ferrochelatase YP_668464.1 565192 D 362663 CDS YP_668465.1 110640737 4189244 complement(566129..567097) 1 NC_008253.1 acetyl esterase 567097 4189244 ECP_0537 Escherichia coli 536 acetyl esterase YP_668465.1 566129 R 362663 CDS YP_668466.1 110640738 4189245 567249..568553 1 NC_008253.1 inosine-guanosine kinase 568553 4189245 ECP_0538 Escherichia coli 536 inosine-guanosine kinase YP_668466.1 567249 D 362663 CDS YP_668467.1 110640739 4189246 complement(568683..570359) 1 NC_008253.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 570359 4189246 ECP_0539 Escherichia coli 536 cation:proton antiport protein YP_668467.1 568683 R 362663 CDS YP_668468.1 110640740 4189247 complement(570597..571817) 1 NC_008253.1 fosmidomycin resistance protein 571817 4189247 ECP_0540 Escherichia coli 536 fosmidomycin resistance protein YP_668468.1 570597 R 362663 CDS YP_668469.1 110640741 4189248 572035..573687 1 NC_008253.1 UDP-sugar hydrolase; catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 573687 ushA 4189248 ushA Escherichia coli 536 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_668469.1 572035 D 362663 CDS YP_668470.1 110640742 4189249 complement(573725..574228) 1 NC_008253.1 hypothetical protein 574228 4189249 ECP_0542 Escherichia coli 536 hypothetical protein YP_668470.1 573725 R 362663 CDS YP_668471.1 110640743 4189250 complement(574225..575025) 1 NC_008253.1 hypothetical protein 575025 4189250 ECP_0543 Escherichia coli 536 hypothetical protein YP_668471.1 574225 R 362663 CDS YP_668472.1 110640744 4189251 complement(575049..575528) 1 NC_008253.1 hypothetical protein 575528 4189251 ECP_0544 Escherichia coli 536 hypothetical protein YP_668472.1 575049 R 362663 CDS YP_668473.1 110640745 4189252 complement(575732..576526) 1 NC_008253.1 ligase; hypothetical protein 576526 4189252 ECP_0545 Escherichia coli 536 hypothetical protein YP_668473.1 575732 R 362663 CDS YP_668474.1 110640746 4189253 576659..576961 1 NC_008253.1 hypothetical protein 576961 4189253 ECP_0546 Escherichia coli 536 hypothetical protein YP_668474.1 576659 D 362663 CDS YP_668475.1 110640747 4189254 576997..577338 1 NC_008253.1 HTH-type transcriptional regulator YbaQ 577338 4189254 ECP_0547 Escherichia coli 536 HTH-type transcriptional regulator YbaQ YP_668475.1 576997 D 362663 CDS YP_668476.1 110640748 4189255 complement(577396..577950) 1 NC_008253.1 copper-transporting P-type ATPase 577950 4189255 ECP_0548 Escherichia coli 536 copper-transporting P-type ATPase YP_668476.1 577396 R 362663 CDS YP_668477.1 110640749 4189256 complement(577943..579901) 1 NC_008253.1 copper-transporting P-type ATPase 579901 4189256 ECP_0549 Escherichia coli 536 copper-transporting P-type ATPase YP_668477.1 577943 R 362663 CDS YP_668478.1 110640750 4189257 580163..581095 1 NC_008253.1 catalyzes the formation of glutamate from glutamine; glutaminase 581095 4189257 ECP_0550 Escherichia coli 536 glutaminase YP_668478.1 580163 D 362663 CDS YP_668479.1 110640751 4191687 581098..582390 1 NC_008253.1 amino acid transporter 582390 4191687 ECP_0551 Escherichia coli 536 amino acid transporter YP_668479.1 581098 D 362663 CDS YP_668480.1 110640752 4191688 582515..582922 1 NC_008253.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 582922 4191688 ECP_0552 Escherichia coli 536 DNA-binding transcriptional regulator CueR YP_668480.1 582515 D 362663 CDS YP_668481.1 110640753 4191689 complement(582923..584146) 1 NC_008253.1 hypothetical protein 584146 4191689 ECP_0553 Escherichia coli 536 hypothetical protein YP_668481.1 582923 R 362663 CDS YP_668482.1 110640754 4191690 complement(584265..584723) 1 NC_008253.1 hypothetical protein 584723 4191690 ECP_0554 Escherichia coli 536 hypothetical protein YP_668482.1 584265 R 362663 CDS YP_668483.1 110640755 4191691 complement(584720..585637) 1 NC_008253.1 hypothetical protein 585637 4191691 ECP_0555 Escherichia coli 536 hypothetical protein YP_668483.1 584720 R 362663 CDS YP_668484.1 110640756 4191692 585783..586460 1 NC_008253.1 ABC transporter ATP-binding protein 586460 4191692 ECP_0556 Escherichia coli 536 ABC transporter ATP-binding protein YP_668484.1 585783 D 362663 CDS YP_668485.1 110640757 4191693 586447..587226 1 NC_008253.1 hypothetical protein 587226 4191693 ECP_0557 Escherichia coli 536 hypothetical protein YP_668485.1 586447 D 362663 CDS YP_668486.1 110640758 4191694 complement(587289..588179) 1 NC_008253.1 thioredoxin YbbN protein 588179 4191694 ECP_0558 Escherichia coli 536 thioredoxin YbbN protein YP_668486.1 587289 R 362663 CDS YP_668487.1 110640759 4191695 complement(588204..588974) 1 NC_008253.1 short chain dehydrogenase 588974 4191695 ECP_0559 Escherichia coli 536 short chain dehydrogenase YP_668487.1 588204 R 362663 CDS YP_668488.1 110640760 4191696 complement(589003..589659) 1 NC_008253.1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 589659 4191696 ECP_0560 Escherichia coli 536 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_668488.1 589003 R 362663 CDS YP_668489.1 110640761 4191697 589597..589824 1 NC_008253.1 similar to N-terminal ATP-binding protein YbbA; ABC transporter 589824 4191697 ECP_0561 Escherichia coli 536 ABC transporter YP_668489.1 589597 D 362663 CDS YP_668490.1 110640762 4191698 589826..590284 1 NC_008253.1 similar to C-terminal ATP-binding protein YbbA; ABC transporter 590284 4191698 ECP_0562 Escherichia coli 536 ABC transporter YP_668490.1 589826 D 362663 CDS YP_668491.1 110640763 4191699 590281..592695 1 NC_008253.1 membrane protein YbbP 592695 4191699 ECP_0563 Escherichia coli 536 membrane protein YbbP YP_668491.1 590281 D 362663 CDS YP_668492.1 110640764 4191700 complement(592836..593930) 1 NC_008253.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 593930 4191700 ECP_0564 Escherichia coli 536 tRNA 2-selenouridine synthase YP_668492.1 592836 R 362663 CDS YP_668493.1 110640765 4191701 complement(593999..594925) 1 NC_008253.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 594925 4191701 ECP_0565 Escherichia coli 536 DNA-binding transcriptional activator AllS YP_668493.1 593999 R 362663 CDS YP_668494.1 110640766 4191702 595155..595637 1 NC_008253.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 595637 4191702 ECP_0566 Escherichia coli 536 ureidoglycolate hydrolase YP_668494.1 595155 D 362663 CDS YP_668495.1 110640767 4191703 595715..596530 1 NC_008253.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 596530 4191703 ECP_0567 Escherichia coli 536 DNA-binding transcriptional repressor AllR YP_668495.1 595715 D 362663 CDS YP_668496.1 110640768 4191704 596620..598401 1 NC_008253.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 598401 4191704 ECP_0568 Escherichia coli 536 glyoxylate carboligase YP_668496.1 596620 D 362663 CDS YP_668497.1 110640769 4191705 598414..599190 1 NC_008253.1 hydroxypyruvate isomerase 599190 4191705 ECP_0569 Escherichia coli 536 hydroxypyruvate isomerase YP_668497.1 598414 D 362663 CDS YP_668498.1 110640770 4189508 599290..600168 1 NC_008253.1 2-hydroxy-3-oxopropionate reductase 600168 4189508 ECP_0570 Escherichia coli 536 2-hydroxy-3-oxopropionate reductase YP_668498.1 599290 D 362663 CDS YP_668499.1 110640771 4189509 600338..601792 1 NC_008253.1 allantoin permease 601792 4189509 ECP_0571 Escherichia coli 536 allantoin permease YP_668499.1 600338 D 362663 CDS YP_668500.1 110640772 4189510 601852..603213 1 NC_008253.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 603213 4189510 ECP_0572 Escherichia coli 536 allantoinase YP_668500.1 601852 D 362663 CDS YP_668501.1 110640773 4189511 603269..604570 1 NC_008253.1 purine permease YbbY 604570 4189511 ECP_0573 Escherichia coli 536 purine permease YbbY YP_668501.1 603269 D 362663 CDS YP_668502.1 110640774 4189512 604592..605737 1 NC_008253.1 glycerate kinase 605737 4189512 ECP_0574 Escherichia coli 536 glycerate kinase YP_668502.1 604592 D 362663 CDS YP_668503.1 110640775 4189513 complement(605866..606651) 1 NC_008253.1 hypothetical protein 606651 4189513 ECP_0575 Escherichia coli 536 hypothetical protein YP_668503.1 605866 R 362663 CDS YP_668504.1 110640776 4189514 complement(606662..607897) 1 NC_008253.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 607897 4189514 ECP_0576 Escherichia coli 536 allantoate amidohydrolase YP_668504.1 606662 R 362663 CDS YP_668505.1 110640777 4189515 complement(607919..608968) 1 NC_008253.1 malate/L-lactate dehydrogenase 608968 4189515 ECP_0577 Escherichia coli 536 malate/L-lactate dehydrogenase YP_668505.1 607919 R 362663 CDS YP_668506.1 110640778 4189516 609285..610952 1 NC_008253.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 610952 4189516 ECP_0578 Escherichia coli 536 membrane protein FdrA YP_668506.1 609285 D 362663 CDS YP_668507.1 110640779 4189517 610962..612221 1 NC_008253.1 hypothetical protein 612221 4189517 ECP_0579 Escherichia coli 536 hypothetical protein YP_668507.1 610962 D 362663 CDS YP_668508.1 110640780 4189518 612232..613047 1 NC_008253.1 hypothetical protein 613047 4189518 ECP_0580 Escherichia coli 536 hypothetical protein YP_668508.1 612232 D 362663 CDS YP_668509.1 110640781 4189519 613044..613937 1 NC_008253.1 carbamate kinase 613937 4189519 ECP_0581 Escherichia coli 536 carbamate kinase YP_668509.1 613044 D 362663 CDS YP_668510.1 110640782 4189520 complement(614070..615137) 1 NC_008253.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 615137 4189520 ECP_0582 Escherichia coli 536 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_668510.1 614070 R 362663 CDS YP_668511.1 110640783 4189521 complement(615134..615643) 1 NC_008253.1 phosphoribosylaminoimidazole carboxylase catalytic subunit 615643 4189521 ECP_0583 Escherichia coli 536 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_668511.1 615134 R 362663 CDS YP_668512.1 110640784 4189522 complement(615739..616068) 1 NC_008253.1 hypothetical protein 616068 4189522 ECP_0584 Escherichia coli 536 hypothetical protein YP_668512.1 615739 R 362663 CDS YP_668513.1 110640785 4189523 complement(616180..616902) 1 NC_008253.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 616902 4189523 ECP_0585 Escherichia coli 536 UDP-2,3-diacylglucosamine hydrolase YP_668513.1 616180 R 362663 CDS YP_668514.1 110640786 4189524 complement(616905..617399) 1 NC_008253.1 peptidyl-prolyl cis-trans isomerase B 617399 4189524 ECP_0586 Escherichia coli 536 peptidyl-prolyl cis-trans isomerase B YP_668514.1 616905 R 362663 CDS YP_668515.1 110640787 4189525 617573..618958 1 NC_008253.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 618958 cysS 4189525 cysS Escherichia coli 536 cysteinyl-tRNA synthetase YP_668515.1 617573 D 362663 CDS YP_668516.1 110640788 4189526 complement(618994..619515) 1 NC_008253.1 membrane-bound metal-dependent hydrolase 619515 4189526 ECP_0588 Escherichia coli 536 membrane-bound metal-dependent hydrolase YP_668516.1 618994 R 362663 CDS YP_668517.1 110640789 4189527 complement(619623..619835) 1 NC_008253.1 hypothetical protein 619835 4189527 ECP_0589 Escherichia coli 536 hypothetical protein YP_668517.1 619623 R 362663 CDS YP_668518.1 110640790 4189889 complement(619837..620703) 1 NC_008253.1 bifunctional; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 620703 4189889 ECP_0590 Escherichia coli 536 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_668518.1 619837 R 362663 CDS YP_668519.1 110640791 4189890 620744..620941 1 NC_008253.1 hypothetical protein 620941 4189890 ECP_0591 Escherichia coli 536 hypothetical protein YP_668519.1 620744 D 362663 CDS YP_668520.1 110640792 4189892 complement(621058..621366) 1 NC_008253.1 similar to C-terminal prophage DLP12 integrase; DNA integration/recombination/invertion protein 621366 4189892 ECP_0593 Escherichia coli 536 DNA integration/recombination/invertion protein YP_668520.1 621058 R 362663 CDS YP_668521.1 110640793 4189893 complement(621386..621685) 1 NC_008253.1 similar to N-terminal prophage DLP12 integrase; DNA integration/recombination/invertion protein 621685 4189893 ECP_0594 Escherichia coli 536 DNA integration/recombination/invertion protein YP_668521.1 621386 R 362663 CDS YP_668522.1 110640794 4189894 621739..621921 1 NC_008253.1 hypothetical protein 621921 4189894 ECP_0595 Escherichia coli 536 hypothetical protein YP_668522.1 621739 D 362663 CDS YP_668523.1 110640795 4189895 complement(622098..622754) 1 NC_008253.1 hypothetical protein 622754 4189895 ECP_0596 Escherichia coli 536 hypothetical protein YP_668523.1 622098 R 362663 CDS YP_668524.1 110640796 4189896 complement(622998..623951) 1 NC_008253.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 623951 4189896 ECP_0597 Escherichia coli 536 outer membrane protease YP_668524.1 622998 R 362663 CDS YP_668525.1 110640797 4189897 complement(624610..625500) 1 NC_008253.1 hypothetical protein 625500 4189897 ECP_0598 Escherichia coli 536 hypothetical protein YP_668525.1 624610 R 362663 CDS YP_668526.1 110640798 4189898 complement(625501..628473) 1 NC_008253.1 bacteriophage N4 receptor, outer membrane subunit 628473 4189898 ECP_0599 Escherichia coli 536 bacteriophage N4 receptor, outer membrane subunit YP_668526.1 625501 R 362663 CDS YP_668527.1 110640799 4189899 complement(628460..630697) 1 NC_008253.1 bacteriophage N4 adsorption protein B 630697 nfrB 4189899 nfrB Escherichia coli 536 bacteriophage N4 adsorption protein B YP_668527.1 628460 R 362663 CDS YP_668528.1 110640800 4189900 complement(630847..632289) 1 NC_008253.1 sensor kinase CusS 632289 4189900 ECP_0601 Escherichia coli 536 sensor kinase CusS YP_668528.1 630847 R 362663 CDS YP_668529.1 110640801 4189901 complement(632279..632962) 1 NC_008253.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 632962 4189901 ECP_0602 Escherichia coli 536 DNA-binding transcriptional activator CusR YP_668529.1 632279 R 362663 CDS YP_668530.1 110640802 4189902 633119..634501 1 NC_008253.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 634501 4189902 ECP_0603 Escherichia coli 536 copper/silver efflux system outer membrane protein CusC YP_668530.1 633119 D 362663 CDS YP_668531.1 110640803 4189903 634525..634857 1 NC_008253.1 copper-binding protein 634857 4189903 ECP_0604 Escherichia coli 536 copper-binding protein YP_668531.1 634525 D 362663 CDS YP_668532.1 110640804 4189904 634873..636096 1 NC_008253.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 636096 4189904 ECP_0605 Escherichia coli 536 copper/silver efflux system membrane fusion protein CusB YP_668532.1 634873 D 362663 CDS YP_668533.1 110640805 4189905 636108..639251 1 NC_008253.1 cation efflux system protein CusA 639251 4189905 ECP_0606 Escherichia coli 536 cation efflux system protein CusA YP_668533.1 636108 D 362663 CDS YP_668534.1 110640806 4189906 639353..640735 1 NC_008253.1 phenylalanine transporter 640735 4189906 ECP_0607 Escherichia coli 536 phenylalanine transporter YP_668534.1 639353 D 362663 CDS YP_668535.1 110640807 4191838 complement(640893..642140) 1 NC_008253.1 transporter 642140 4191838 ECP_0608 Escherichia coli 536 transporter YP_668535.1 640893 R 362663 CDS YP_668536.1 110640808 4191839 complement(642248..642901) 1 NC_008253.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 642901 4191839 ECP_0609 Escherichia coli 536 dihydropteridine reductase YP_668536.1 642248 R 362663 CDS YP_668537.1 110640809 4191840 complement(642980..643363) 1 NC_008253.1 hypothetical protein 643363 4191840 ECP_0610 Escherichia coli 536 hypothetical protein YP_668537.1 642980 R 362663 CDS YP_668538.1 110640810 4191841 complement(643428..643676) 1 NC_008253.1 membrane protein YbdJ 643676 4191841 ECP_0611 Escherichia coli 536 membrane protein YbdJ YP_668538.1 643428 R 362663 CDS YP_668539.1 110640811 4191842 complement(643742..644860) 1 NC_008253.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 644860 4191842 ECP_0612 Escherichia coli 536 carboxylate-amine ligase YP_668539.1 643742 R 362663 CDS YP_668540.1 110640812 4191843 645269..645457 1 NC_008253.1 hypothetical protein 645457 4191843 ECP_0613 Escherichia coli 536 hypothetical protein YP_668540.1 645269 D 362663 CDS YP_668541.1 110640813 4191844 complement(645579..646208) 1 NC_008253.1 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 646208 4191844 ECP_0614 Escherichia coli 536 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_668541.1 645579 R 362663 CDS YP_668542.1 110640814 4191845 complement(646374..648623) 1 NC_008253.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 648623 4191845 ECP_0615 Escherichia coli 536 outer membrane receptor FepA YP_668542.1 646374 R 362663 CDS YP_668543.1 110640815 4191846 648865..650067 1 NC_008253.1 enterobactin/ferric enterobactin esterase 650067 4191846 ECP_0616 Escherichia coli 536 enterobactin/ferric enterobactin esterase YP_668543.1 648865 D 362663 CDS YP_668544.1 110640816 4191847 650070..650288 1 NC_008253.1 MbtH-like protein 650288 4191847 ECP_0617 Escherichia coli 536 MbtH-like protein YP_668544.1 650070 D 362663 CDS YP_668545.1 110640817 4191848 650285..654166 1 NC_008253.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 654166 entF 4191848 entF Escherichia coli 536 enterobactin synthase subunit F YP_668545.1 650285 D 362663 CDS YP_668546.1 110640818 4191849 654382..655515 1 NC_008253.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 655515 4191849 ECP_0619 Escherichia coli 536 ferric enterobactin transport protein FepE YP_668546.1 654382 D 362663 CDS YP_668547.1 110640819 4191850 complement(655512..656327) 1 NC_008253.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 656327 4191850 ECP_0620 Escherichia coli 536 iron-enterobactin transporter ATP-binding protein YP_668547.1 655512 R 362663 CDS YP_668548.1 110640820 4191851 complement(656324..657316) 1 NC_008253.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 657316 4191851 ECP_0621 Escherichia coli 536 iron-enterobactin transporter permease YP_668548.1 656324 R 362663 CDS YP_668549.1 110640821 4191852 complement(657313..658329) 1 NC_008253.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 658329 4191852 ECP_0622 Escherichia coli 536 iron-enterobactin transporter membrane protein YP_668549.1 657313 R 362663 CDS YP_668550.1 110640822 4191853 658428..659678 1 NC_008253.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 659678 4191853 ECP_0623 Escherichia coli 536 enterobactin exporter EntS YP_668550.1 658428 D 362663 CDS YP_668551.1 110640823 4191854 complement(659682..660638) 1 NC_008253.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 660638 4191854 ECP_0624 Escherichia coli 536 iron-enterobactin transporter periplasmic binding protein YP_668551.1 659682 R 362663 CDS YP_668552.1 110640824 4191855 660827..662002 1 NC_008253.1 isochorismate synthase 662002 4191855 ECP_0625 Escherichia coli 536 isochorismate synthase YP_668552.1 660827 D 362663 CDS YP_668553.1 110640825 4191856 662012..663622 1 NC_008253.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 663622 entE 4191856 entE Escherichia coli 536 enterobactin synthase subunit E YP_668553.1 662012 D 362663 CDS YP_668554.1 110640826 4191857 663636..664493 1 NC_008253.1 isochorismatase 664493 4191857 ECP_0627 Escherichia coli 536 isochorismatase YP_668554.1 663636 D 362663 CDS YP_668555.1 110640827 4188185 664493..665239 1 NC_008253.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 665239 4188185 ECP_0628 Escherichia coli 536 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_668555.1 664493 D 362663 CDS YP_668556.1 110640828 4188186 665242..665655 1 NC_008253.1 hypothetical protein 665655 4188186 ECP_0629 Escherichia coli 536 hypothetical protein YP_668556.1 665242 D 362663 CDS YP_668557.1 110640829 4188187 665836..667941 1 NC_008253.1 carbon starvation protein A 667941 4188187 ECP_0630 Escherichia coli 536 carbon starvation protein A YP_668557.1 665836 D 362663 CDS YP_668558.1 110640830 4188188 668053..668250 1 NC_008253.1 hypothetical protein 668250 4188188 ECP_0631 Escherichia coli 536 hypothetical protein YP_668558.1 668053 D 362663 CDS YP_668559.1 110640831 4188189 complement(668260..669348) 1 NC_008253.1 member of the iron-containing alcohol dehydrogenase; unknown function; hypothetical protein 669348 4188189 ECP_0632 Escherichia coli 536 hypothetical protein YP_668559.1 668260 R 362663 CDS YP_668560.1 110640832 4188190 669457..670617 1 NC_008253.1 catalyzes the transfer of an amino moiety; aminotransferase 670617 4188190 ECP_0633 Escherichia coli 536 aminotransferase YP_668560.1 669457 D 362663 CDS YP_668561.1 110640833 4188191 complement(670618..671247) 1 NC_008253.1 hypothetical protein 671247 4188191 ECP_0634 Escherichia coli 536 hypothetical protein YP_668561.1 670618 R 362663 CDS YP_668562.1 110640834 4188192 complement(671220..672440) 1 NC_008253.1 hypothetical protein 672440 4188192 ECP_0635 Escherichia coli 536 hypothetical protein YP_668562.1 671220 R 362663 CDS YP_668563.1 110640835 4188193 complement(672587..673489) 1 NC_008253.1 transcriptional regulator YbdO 673489 4188193 ECP_0636 Escherichia coli 536 transcriptional regulator YbdO YP_668563.1 672587 R 362663 CDS YP_668564.1 110640836 4188194 complement(673694..674440) 1 NC_008253.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 674440 dsbG 4188194 dsbG Escherichia coli 536 disulfide isomerase/thiol-disulfide oxidase YP_668564.1 673694 R 362663 CDS YP_668565.1 110640837 4188195 674812..675375 1 NC_008253.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 675375 4188195 ECP_0638 Escherichia coli 536 alkyl hydroperoxide reductase YP_668565.1 674812 D 362663 CDS YP_668566.1 110640838 4188196 675516..677111 1 NC_008253.1 alkyl hydroperoxide reductase 677111 4188196 ECP_0639 Escherichia coli 536 alkyl hydroperoxide reductase YP_668566.1 675516 D 362663 CDS YP_668567.1 110640839 4188197 complement(677232..677660) 1 NC_008253.1 universal stress protein 677660 4188197 ECP_0640 Escherichia coli 536 universal stress protein YP_668567.1 677232 R 362663 CDS YP_668568.1 110640840 4188198 complement(678016..678426) 1 NC_008253.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 678426 4188198 ECP_0641 Escherichia coli 536 nucleoside diphosphate kinase regulator YP_668568.1 678016 R 362663 CDS YP_668569.1 110640841 4188199 complement(678656..679480) 1 NC_008253.1 ribonuclease I 679480 4188199 ECP_0642 Escherichia coli 536 ribonuclease I YP_668569.1 678656 R 362663 CDS YP_668570.1 110640842 4188200 complement(679576..681039) 1 NC_008253.1 citrate/succinate antiporter 681039 4188200 ECP_0643 Escherichia coli 536 citrate/succinate antiporter YP_668570.1 679576 R 362663 CDS YP_668571.1 110640843 4188201 complement(681090..681968) 1 NC_008253.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 681968 citG 4188201 citG Escherichia coli 536 triphosphoribosyl-dephospho-CoA synthase YP_668571.1 681090 R 362663 CDS YP_668572.1 110640844 4188202 complement(681943..682494) 1 NC_008253.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase 682494 citX 4188202 citX Escherichia coli 536 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase YP_668572.1 681943 R 362663 CDS YP_668573.1 110640845 4188203 complement(682498..684030) 1 NC_008253.1 citrate lyase subunit alpha 684030 4188203 ECP_0646 Escherichia coli 536 citrate lyase subunit alpha YP_668573.1 682498 R 362663 CDS YP_668574.1 110640846 4188471 complement(684041..684949) 1 NC_008253.1 citrate lyase subunit beta 684949 4188471 ECP_0647 Escherichia coli 536 citrate lyase subunit beta YP_668574.1 684041 R 362663 CDS YP_668575.1 110640847 4188472 complement(684946..685242) 1 NC_008253.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 685242 4188472 ECP_0648 Escherichia coli 536 citrate lyase subunit gamma YP_668575.1 684946 R 362663 CDS YP_668576.1 110640848 4188473 complement(685257..686315) 1 NC_008253.1 citrate lyase synthetase 686315 4188473 ECP_0649 Escherichia coli 536 citrate lyase synthetase YP_668576.1 685257 R 362663 CDS YP_668577.1 110640849 4188474 686695..688353 1 NC_008253.1 sensor kinase DpiB 688353 4188474 ECP_0650 Escherichia coli 536 sensor kinase DpiB YP_668577.1 686695 D 362663 CDS YP_668578.1 110640850 4188475 688322..689002 1 NC_008253.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 689002 dpiA 4188475 dpiA Escherichia coli 536 two-component response regulator DpiA YP_668578.1 688322 D 362663 CDS YP_668579.1 110640851 4188476 complement(689043..690428) 1 NC_008253.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 690428 dcuC 4188476 dcuC Escherichia coli 536 C4-dicarboxylate transporter DcuC YP_668579.1 689043 R 362663 CDS YP_668580.1 110640852 4188477 691015..691575 1 NC_008253.1 antimicrobial peptide resistance and lipid A acylation protein; catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 691575 pagP 4188477 pagP Escherichia coli 536 palmitoyl transferase YP_668580.1 691015 D 362663 CDS YP_668581.1 110640853 4188478 691750..691959 1 NC_008253.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 691959 cspE 4188478 cspE Escherichia coli 536 cold shock protein CspE YP_668581.1 691750 D 362663 CDS YP_668582.1 110640854 4188479 complement(692013..692396) 1 NC_008253.1 protein CrcB 692396 4188479 ECP_0655 Escherichia coli 536 protein CrcB YP_668582.1 692013 R 362663 CDS YP_668583.1 110640855 4188480 692492..693280 1 NC_008253.1 hypothetical protein 693280 4188480 ECP_0656 Escherichia coli 536 hypothetical protein YP_668583.1 692492 D 362663 CDS YP_668584.1 110640856 4188481 693409..693612 1 NC_008253.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase E 693612 tatE 4188481 tatE Escherichia coli 536 twin arginine translocase E YP_668584.1 693409 D 362663 CDS YP_668585.1 110640857 4188482 complement(693712..694677) 1 NC_008253.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 694677 4188482 ECP_0658 Escherichia coli 536 lipoyl synthase YP_668585.1 693712 R 362663 CDS YP_668586.1 110640858 4188483 complement(694909..695097) 1 NC_008253.1 hypothetical protein 695097 4188483 ECP_0659 Escherichia coli 536 hypothetical protein YP_668586.1 694909 R 362663 CDS YP_668587.1 110640859 4188484 complement(695497..696138) 1 NC_008253.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 696138 lipB 4188484 lipB Escherichia coli 536 lipoyltransferase YP_668587.1 695497 R 362663 CDS YP_668588.1 110640860 4188485 complement(696239..696502) 1 NC_008253.1 hypothetical protein 696502 4188485 ECP_0661 Escherichia coli 536 hypothetical protein YP_668588.1 696239 R 362663 CDS YP_668589.1 110640861 4188486 complement(696612..697823) 1 NC_008253.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 697823 4188486 ECP_0662 Escherichia coli 536 D-alanyl-D-alanine carboxypeptidase YP_668589.1 696612 R 362663 CDS YP_668590.1 110640862 4188487 complement(697963..699051) 1 NC_008253.1 rare lipoprotein A 699051 4188487 ECP_0663 Escherichia coli 536 rare lipoprotein A YP_668590.1 697963 R 362663 CDS YP_668591.1 110640863 4188488 complement(699062..700174) 1 NC_008253.1 cell wall shape-determining protein 700174 4188488 ECP_0664 Escherichia coli 536 cell wall shape-determining protein YP_668591.1 699062 R 362663 CDS YP_668592.1 110640864 4188489 complement(700177..702078) 1 NC_008253.1 penicillin-binding protein 2 702078 4188489 ECP_0665 Escherichia coli 536 penicillin-binding protein 2 YP_668592.1 700177 R 362663 CDS YP_668593.1 110640865 4188490 complement(702109..702576) 1 NC_008253.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 702576 4188490 ECP_0666 Escherichia coli 536 rRNA large subunit methyltransferase YP_668593.1 702109 R 362663 CDS YP_668594.1 110640866 4190913 complement(702580..702897) 1 NC_008253.1 hypothetical protein 702897 4190913 ECP_0667 Escherichia coli 536 hypothetical protein YP_668594.1 702580 R 362663 CDS YP_668595.1 110640867 4190914 complement(703157..703768) 1 NC_008253.1 phosphoglycerate mutase 703768 4190914 ECP_0668 Escherichia coli 536 phosphoglycerate mutase YP_668595.1 703157 R 362663 CDS YP_668596.1 110640868 4190915 complement(703792..704433) 1 NC_008253.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 704433 nadD 4190915 nadD Escherichia coli 536 nicotinic acid mononucleotide adenylyltransferase YP_668596.1 703792 R 362663 CDS YP_668597.1 110640869 4190916 complement(704435..705466) 1 NC_008253.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 705466 holA 4190916 holA Escherichia coli 536 DNA polymerase III subunit delta YP_668597.1 704435 R 362663 CDS YP_668598.1 110640870 4190917 complement(705466..706047) 1 NC_008253.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 706047 4190917 ECP_0671 Escherichia coli 536 LPS-assembly lipoprotein RlpB YP_668598.1 705466 R 362663 CDS YP_668599.1 110640871 4190918 complement(706062..708644) 1 NC_008253.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 708644 leuS 4190918 leuS Escherichia coli 536 leucyl-tRNA synthetase YP_668599.1 706062 R 362663 CDS YP_668600.1 110640872 4190919 708879..709361 1 NC_008253.1 hypothetical protein 709361 4190919 ECP_0673 Escherichia coli 536 hypothetical protein YP_668600.1 708879 D 362663 CDS YP_668601.1 110640873 4190920 complement(709406..710341) 1 NC_008253.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 710341 rihA 4190920 rihA Escherichia coli 536 ribonucleoside hydrolase 1 YP_668601.1 709406 R 362663 CDS YP_668602.1 110640874 4190921 complement(710459..711184) 1 NC_008253.1 glutamate/aspartate transport ATP-binding protein GltL 711184 4190921 ECP_0675 Escherichia coli 536 glutamate/aspartate transport ATP-binding protein GltL YP_668602.1 710459 R 362663 CDS YP_668603.1 110640875 4190922 complement(711184..711858) 1 NC_008253.1 glutamate/aspartate transport system permease GltK 711858 4190922 ECP_0676 Escherichia coli 536 glutamate/aspartate transport system permease GltK YP_668603.1 711184 R 362663 CDS YP_668604.1 110640876 4190923 complement(711858..712598) 1 NC_008253.1 glutamate/aspartate transport system permease GltJ 712598 4190923 ECP_0677 Escherichia coli 536 glutamate/aspartate transport system permease GltJ YP_668604.1 711858 R 362663 CDS YP_668605.1 110640877 4190924 complement(712768..713676) 1 NC_008253.1 glutamate and aspartate transporter subunit 713676 4190924 ECP_0678 Escherichia coli 536 glutamate and aspartate transporter subunit YP_668605.1 712768 R 362663 CDS YP_668606.1 110640878 4190925 714130..716007 1 NC_008253.1 outer membrane protein 716007 4190925 ECP_0679 Escherichia coli 536 outer membrane protein YP_668606.1 714130 D 362663 CDS YP_668607.1 110640879 4190926 complement(716134..717672) 1 NC_008253.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 717672 lnt 4190926 lnt Escherichia coli 536 apolipoprotein N-acyltransferase YP_668607.1 716134 R 362663 CDS YP_668608.1 110640880 4190927 complement(717697..718575) 1 NC_008253.1 magnesium and cobalt efflux protein CorC 718575 4190927 ECP_0681 Escherichia coli 536 magnesium and cobalt efflux protein CorC YP_668608.1 717697 R 362663 CDS YP_668609.1 110640881 4190928 complement(718665..719132) 1 NC_008253.1 metalloprotease 719132 4190928 ECP_0682 Escherichia coli 536 metalloprotease YP_668609.1 718665 R 362663 CDS YP_668610.1 110640882 4190929 complement(719129..720208) 1 NC_008253.1 ATP-binding PhoH-like protein 720208 4190929 ECP_0683 Escherichia coli 536 ATP-binding PhoH-like protein YP_668610.1 719129 R 362663 CDS YP_668611.1 110640883 4190930 complement(720322..721746) 1 NC_008253.1 tRNA-thiotransferase; MiaB protein 721746 4190930 ECP_0684 Escherichia coli 536 MiaB protein YP_668611.1 720322 R 362663 CDS YP_668612.1 110640884 4190931 721892..723067 1 NC_008253.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 723067 ubiF 4190931 ubiF Escherichia coli 536 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_668612.1 721892 D 362663 CDS YP_668613.1 110640885 4190061 complement(723914..725578) 1 NC_008253.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 725578 asnB 4190061 asnB Escherichia coli 536 asparagine synthetase B YP_668613.1 723914 R 362663 CDS YP_668614.1 110640886 4190062 complement(725835..726587) 1 NC_008253.1 UMP phosphatase 726587 4190062 ECP_0687 Escherichia coli 536 UMP phosphatase YP_668614.1 725835 R 362663 CDS YP_668615.1 110640887 4190063 complement(726635..727855) 1 NC_008253.1 N-acetylglucosamine repressor NagC 727855 4190063 ECP_0688 Escherichia coli 536 N-acetylglucosamine repressor NagC YP_668615.1 726635 R 362663 CDS YP_668616.1 110640888 4190064 complement(727864..729012) 1 NC_008253.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 729012 nagA 4190064 nagA Escherichia coli 536 N-acetylglucosamine-6-phosphate deacetylase YP_668616.1 727864 R 362663 CDS YP_668617.1 110640889 4190065 complement(729072..729872) 1 NC_008253.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 729872 nagB 4190065 nagB Escherichia coli 536 glucosamine-6-phosphate deaminase YP_668617.1 729072 R 362663 CDS YP_668618.1 110640890 4190066 730205..732151 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; N-acetyl glucosamine specific PTS system components IIABC 732151 4190066 ECP_0691 Escherichia coli 536 N-acetyl glucosamine specific PTS system components IIABC YP_668618.1 730205 D 362663 CDS YP_668619.1 110640891 4190067 complement(732240..733754) 1 NC_008253.1 membrane transporter 733754 4190067 ECP_0692 Escherichia coli 536 membrane transporter YP_668619.1 732240 R 362663 CDS YP_668620.1 110640892 4190068 complement(734001..735170) 1 NC_008253.1 hypothetical protein 735170 4190068 ECP_0693 Escherichia coli 536 hypothetical protein YP_668620.1 734001 R 362663 CDS YP_668621.1 110640893 4190069 complement(735206..735964) 1 NC_008253.1 integral membrane transport protein 735964 4190069 ECP_0694 Escherichia coli 536 integral membrane transport protein YP_668621.1 735206 R 362663 CDS YP_668622.1 110640894 4190070 complement(736024..736911) 1 NC_008253.1 dihydrodipicolinate synthase 736911 4190070 ECP_0695 Escherichia coli 536 dihydrodipicolinate synthase YP_668622.1 736024 R 362663 CDS YP_668623.1 110640895 4190071 complement(736915..738072) 1 NC_008253.1 iron-containing alcohol dehydrogenase 738072 4190071 ECP_0696 Escherichia coli 536 iron-containing alcohol dehydrogenase YP_668623.1 736915 R 362663 CDS YP_668624.1 110640896 4190072 738242..739477 1 NC_008253.1 inner membrane protein 739477 4190072 ECP_0697 Escherichia coli 536 inner membrane protein YP_668624.1 738242 D 362663 CDS YP_668625.1 110640897 4190073 739470..740456 1 NC_008253.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 740456 pdxA 4190073 pdxA Escherichia coli 536 4-hydroxythreonine-4-phosphate dehydrogenase YP_668625.1 739470 D 362663 CDS YP_668626.1 110640898 4190074 740458..741219 1 NC_008253.1 DeoR family transcriptional regulator 741219 4190074 ECP_0699 Escherichia coli 536 DeoR family transcriptional regulator YP_668626.1 740458 D 362663 CDS YP_668627.1 110640899 4190075 741439..743103 1 NC_008253.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 743103 4190075 ECP_0700 Escherichia coli 536 glutaminyl-tRNA synthetase YP_668627.1 741439 D 362663 CDS YP_668628.1 110640900 4190076 743544..744950 1 NC_008253.1 outer membrane protein YbfM 744950 4190076 ECP_0701 Escherichia coli 536 outer membrane protein YbfM YP_668628.1 743544 D 362663 CDS YP_668629.1 110640901 4190077 745000..745326 1 NC_008253.1 lipoprotein YbfN 745326 4190077 ECP_0702 Escherichia coli 536 lipoprotein YbfN YP_668629.1 745000 D 362663 CDS YP_668630.1 110640902 4190078 complement(745410..745856) 1 NC_008253.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 745856 fur 4190078 fur Escherichia coli 536 ferric uptake regulator YP_668630.1 745410 R 362663 CDS YP_668631.1 110640903 4190079 745901..746155 1 NC_008253.1 hypothetical protein 746155 4190079 ECP_0704 Escherichia coli 536 hypothetical protein YP_668631.1 745901 D 362663 CDS YP_668632.1 110640904 4190080 complement(746145..746675) 1 NC_008253.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 746675 4190080 ECP_0705 Escherichia coli 536 flavodoxin FldA YP_668632.1 746145 R 362663 CDS YP_668633.1 110640905 4187737 complement(746815..747177) 1 NC_008253.1 LexA regulated protein 747177 4187737 ECP_0706 Escherichia coli 536 LexA regulated protein YP_668633.1 746815 R 362663 CDS YP_668634.1 110640906 4187738 complement(747248..748012) 1 NC_008253.1 hypothetical protein 748012 4187738 ECP_0707 Escherichia coli 536 hypothetical protein YP_668634.1 747248 R 362663 CDS YP_668635.1 110640907 4187739 748197..748742 1 NC_008253.1 negative modulator of initiation of replication; negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 748742 4187739 ECP_0708 Escherichia coli 536 replication initiation regulator SeqA YP_668635.1 748197 D 362663 CDS YP_668636.1 110640908 4187740 748768..750408 1 NC_008253.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 750408 4187740 ECP_0709 Escherichia coli 536 phosphoglucomutase YP_668636.1 748768 D 362663 CDS YP_668637.1 110640909 4187741 complement(750465..751784) 1 NC_008253.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 751784 potE 4187741 potE Escherichia coli 536 putrescine transporter YP_668637.1 750465 R 362663 CDS YP_668638.1 110640910 4187742 complement(751781..753988) 1 NC_008253.1 ornithine decarboxylase 753988 4187742 ECP_0711 Escherichia coli 536 ornithine decarboxylase YP_668638.1 751781 R 362663 CDS YP_668639.1 110640911 4187743 complement(754668..755345) 1 NC_008253.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 755345 4187743 ECP_0712 Escherichia coli 536 DNA-binding transcriptional activator KdpE YP_668639.1 754668 R 362663 CDS YP_668640.1 110640912 4187746 complement(758020..758592) 1 NC_008253.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 758592 4187746 ECP_0715 Escherichia coli 536 potassium-transporting ATPase subunit C YP_668640.1 758020 R 362663 CDS YP_668641.1 110640913 4187747 complement(758601..760649) 1 NC_008253.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 760649 4187747 ECP_0716 Escherichia coli 536 potassium-transporting ATPase subunit B YP_668641.1 758601 R 362663 CDS YP_668642.1 110640914 4187748 complement(760672..762345) 1 NC_008253.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 762345 4187748 ECP_0717 Escherichia coli 536 potassium-transporting ATPase subunit A YP_668642.1 760672 R 362663 CDS YP_668643.1 110640915 4187749 complement(762345..762434) 1 NC_008253.1 hypothetical protein 762434 4187749 ECP_0718 Escherichia coli 536 hypothetical protein YP_668643.1 762345 R 362663 CDS YP_668644.1 110640916 4187750 762747..762953 1 NC_008253.1 hypothetical protein 762953 4187750 ECP_0719 Escherichia coli 536 hypothetical protein YP_668644.1 762747 D 362663 CDS YP_668645.1 110640917 4187751 763054..763563 1 NC_008253.1 hypothetical protein 763563 4187751 ECP_0720 Escherichia coli 536 hypothetical protein YP_668645.1 763054 D 362663 CDS YP_668646.1 110640918 4187752 763560..764978 1 NC_008253.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 764978 4187752 ECP_0721 Escherichia coli 536 deoxyribodipyrimidine photolyase YP_668646.1 763560 D 362663 CDS YP_668647.1 110640919 4187753 complement(765020..766501) 1 NC_008253.1 POT family transport protein YbgH 766501 4187753 ECP_0722 Escherichia coli 536 POT family transport protein YbgH YP_668647.1 765020 R 362663 CDS YP_668648.1 110640920 4191405 766772..767515 1 NC_008253.1 hydrolase-oxidase 767515 4191405 ECP_0723 Escherichia coli 536 hydrolase-oxidase YP_668648.1 766772 D 362663 CDS YP_668649.1 110640921 4191406 767538..768323 1 NC_008253.1 hypothetical protein 768323 4191406 ECP_0724 Escherichia coli 536 hypothetical protein YP_668649.1 767538 D 362663 CDS YP_668650.1 110640922 4191407 768202..769134 1 NC_008253.1 carboxylase; hypothetical protein 769134 4191407 ECP_0725 Escherichia coli 536 hypothetical protein YP_668650.1 768202 D 362663 CDS YP_668651.1 110640923 4191408 769124..769858 1 NC_008253.1 LamB/YcsF family protein 769858 4191408 ECP_0726 Escherichia coli 536 LamB/YcsF family protein YP_668651.1 769124 D 362663 CDS YP_668652.1 110640924 4191409 769894..770685 1 NC_008253.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 770685 4191409 ECP_0727 Escherichia coli 536 endonuclease VIII YP_668652.1 769894 D 362663 CDS YP_668653.1 110640925 4191410 complement(770682..771728) 1 NC_008253.1 hypothetical protein 771728 4191410 ECP_0728 Escherichia coli 536 hypothetical protein YP_668653.1 770682 R 362663 CDS YP_668654.1 110640926 4191411 complement(771880..771990) 1 NC_008253.1 hypothetical protein 771990 4191411 ECP_0729 Escherichia coli 536 hypothetical protein YP_668654.1 771880 R 362663 CDS YP_668655.1 110640927 4191412 complement(772012..772245) 1 NC_008253.1 hypothetical protein 772245 4191412 ECP_0730 Escherichia coli 536 hypothetical protein YP_668655.1 772012 R 362663 CDS YP_668656.1 110640928 4191413 complement(772402..773685) 1 NC_008253.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 773685 gltA 4191413 gltA Escherichia coli 536 type II citrate synthase YP_668656.1 772402 R 362663 CDS YP_668657.1 110640929 4191414 773667..773858 1 NC_008253.1 hypothetical protein 773858 4191414 ECP_0732 Escherichia coli 536 hypothetical protein YP_668657.1 773667 D 362663 CDS YP_668658.1 110640930 4191415 774379..774783 1 NC_008253.1 succinate dehydrogenase cytochrome b556 large membrane subunit 774783 sdhC 4191415 sdhC Escherichia coli 536 succinate dehydrogenase cytochrome b556 large membrane subunit YP_668658.1 774379 D 362663 CDS YP_668659.1 110640931 4191416 774777..775124 1 NC_008253.1 succinate dehydrogenase cytochrome b556 small membrane subunit 775124 sdhD 4191416 sdhD Escherichia coli 536 succinate dehydrogenase cytochrome b556 small membrane subunit YP_668659.1 774777 D 362663 CDS YP_668660.1 110640932 4191417 775124..776890 1 NC_008253.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 776890 sdhA 4191417 sdhA Escherichia coli 536 succinate dehydrogenase flavoprotein subunit YP_668660.1 775124 D 362663 CDS YP_668661.1 110640933 4191418 776906..777622 1 NC_008253.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 777622 sdhB 4191418 sdhB Escherichia coli 536 succinate dehydrogenase iron-sulfur subunit YP_668661.1 776906 D 362663 CDS YP_668662.1 110640934 4191419 777984..780785 1 NC_008253.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 780785 sucA 4191419 sucA Escherichia coli 536 2-oxoglutarate dehydrogenase E1 YP_668662.1 777984 D 362663 CDS YP_668663.1 110640935 4191420 780800..782017 1 NC_008253.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 782017 4191420 ECP_0738 Escherichia coli 536 dihydrolipoamide succinyltransferase YP_668663.1 780800 D 362663 CDS YP_668664.1 110640936 4191421 782111..783277 1 NC_008253.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 783277 sucC 4191421 sucC Escherichia coli 536 succinyl-CoA synthetase subunit beta YP_668664.1 782111 D 362663 CDS YP_668665.1 110640937 4191422 783277..784146 1 NC_008253.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 784146 4191422 ECP_0740 Escherichia coli 536 succinyl-CoA synthetase subunit alpha YP_668665.1 783277 D 362663 CDS YP_668666.1 110640938 4191423 784386..785501 1 NC_008253.1 hypothetical protein 785501 4191423 ECP_0741 Escherichia coli 536 hypothetical protein YP_668666.1 784386 D 362663 CDS YP_668667.1 110640939 4190657 785455..785727 1 NC_008253.1 hypothetical protein 785727 4190657 ECP_0742 Escherichia coli 536 hypothetical protein YP_668667.1 785455 D 362663 CDS YP_668668.1 110640940 4190658 786831..788399 1 NC_008253.1 cytochrome D ubiquinol oxidase subunit I 788399 4190658 ECP_0743 Escherichia coli 536 cytochrome D ubiquinol oxidase subunit I YP_668668.1 786831 D 362663 CDS YP_668669.1 110640941 4190659 788415..789554 1 NC_008253.1 cytochrome D ubiquinol oxidase subunit II 789554 4190659 ECP_0744 Escherichia coli 536 cytochrome D ubiquinol oxidase subunit II YP_668669.1 788415 D 362663 CDS YP_668670.1 110640942 4190660 789569..789682 1 NC_008253.1 hypothetical protein 789682 4190660 ECP_0745 Escherichia coli 536 hypothetical protein YP_668670.1 789569 D 362663 CDS YP_668671.1 110640943 4190661 789682..789975 1 NC_008253.1 hypothetical protein 789975 4190661 ECP_0746 Escherichia coli 536 hypothetical protein YP_668671.1 789682 D 362663 CDS YP_668672.1 110640944 4190662 790125..790529 1 NC_008253.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 790529 4190662 ECP_0747 Escherichia coli 536 acyl-CoA thioester hydrolase YP_668672.1 790125 D 362663 CDS YP_668673.1 110640945 4190663 790535..791218 1 NC_008253.1 membrane-spanning inner membrane protein; membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 791218 4190663 ECP_0748 Escherichia coli 536 colicin uptake protein TolQ YP_668673.1 790535 D 362663 CDS YP_668674.1 110640946 4190664 791222..791650 1 NC_008253.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 791650 4190664 ECP_0749 Escherichia coli 536 colicin uptake protein TolR YP_668674.1 791222 D 362663 CDS YP_668675.1 110640947 4190665 791715..792980 1 NC_008253.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 792980 tolA 4190665 tolA Escherichia coli 536 cell envelope integrity inner membrane protein TolA YP_668675.1 791715 D 362663 CDS YP_668676.1 110640948 4190666 793113..794405 1 NC_008253.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 794405 tolB 4190666 tolB Escherichia coli 536 translocation protein TolB YP_668676.1 793113 D 362663 CDS YP_668677.1 110640949 4190667 794440..794961 1 NC_008253.1 peptidoglycan-associated outer membrane lipoprotein 794961 4190667 ECP_0752 Escherichia coli 536 peptidoglycan-associated outer membrane lipoprotein YP_668677.1 794440 D 362663 CDS YP_668678.1 110640950 4190668 794971..795762 1 NC_008253.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 795762 4190668 ECP_0753 Escherichia coli 536 tol-pal system protein YbgF YP_668678.1 794971 D 362663 CDS YP_668679.1 110640951 4188081 796908..797951 1 NC_008253.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 797951 4188081 ECP_0761 Escherichia coli 536 quinolinate synthetase YP_668679.1 796908 D 362663 CDS YP_668680.1 110640952 4188082 797989..798708 1 NC_008253.1 intergral membrane NMN transport protein PnuC 798708 4188082 ECP_0762 Escherichia coli 536 intergral membrane NMN transport protein PnuC YP_668680.1 797989 D 362663 CDS YP_668681.1 110640953 4188083 complement(798705..799646) 1 NC_008253.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 799646 4188083 ECP_0763 Escherichia coli 536 zinc transporter ZitB YP_668681.1 798705 R 362663 CDS YP_668682.1 110640954 4188084 complement(799761..800141) 1 NC_008253.1 hypothetical protein 800141 4188084 ECP_0764 Escherichia coli 536 hypothetical protein YP_668682.1 799761 R 362663 CDS YP_668683.1 110640955 4188085 800457..801509 1 NC_008253.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 801509 4188085 ECP_0765 Escherichia coli 536 phospho-2-dehydro-3-deoxyheptonate aldolase YP_668683.1 800457 D 362663 CDS YP_668684.1 110640956 4188086 complement(801676..802428) 1 NC_008253.1 phosphoglycerate mutase 802428 4188086 ECP_0766 Escherichia coli 536 phosphoglycerate mutase YP_668684.1 801676 R 362663 CDS YP_668685.1 110640957 4188087 complement(802631..803671) 1 NC_008253.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 803671 galM 4188087 galM Escherichia coli 536 aldose 1-epimerase YP_668685.1 802631 R 362663 CDS YP_668686.1 110640958 4188088 complement(803665..804813) 1 NC_008253.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 804813 4188088 ECP_0768 Escherichia coli 536 galactokinase YP_668686.1 803665 R 362663 CDS YP_668687.1 110640959 4188089 complement(804817..805863) 1 NC_008253.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 805863 4188089 ECP_0769 Escherichia coli 536 galactose-1-phosphate uridylyltransferase YP_668687.1 804817 R 362663 CDS YP_668688.1 110640960 4188090 complement(805873..806889) 1 NC_008253.1 UDP-galactose-4-epimerase 806889 4188090 ECP_0770 Escherichia coli 536 UDP-galactose-4-epimerase YP_668688.1 805873 R 362663 CDS YP_668689.1 110640961 4188091 complement(807151..808623) 1 NC_008253.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 808623 4188091 ECP_0771 Escherichia coli 536 molybdenum transport ATP-binding protein ModF YP_668689.1 807151 R 362663 CDS YP_668690.1 110640962 4188092 complement(808691..809479) 1 NC_008253.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 809479 4188092 ECP_0772 Escherichia coli 536 DNA-binding transcriptional regulator ModE YP_668690.1 808691 R 362663 CDS YP_668691.1 110640963 4191073 809608..809757 1 NC_008253.1 outer membrane or exported protein 809757 4191073 ECP_0773 Escherichia coli 536 outer membrane or exported protein YP_668691.1 809608 D 362663 CDS YP_668692.1 110640964 4191074 809693..809902 1 NC_008253.1 hypothetical protein 809902 4191074 ECP_0774 Escherichia coli 536 hypothetical protein YP_668692.1 809693 D 362663 CDS YP_668693.1 110640965 4191075 809924..810697 1 NC_008253.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 810697 modA 4191075 modA Escherichia coli 536 molybdate transporter periplasmic protein YP_668693.1 809924 D 362663 CDS YP_668694.1 110640966 4191076 810697..811386 1 NC_008253.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 811386 modB 4191076 modB Escherichia coli 536 molybdate ABC transporter permease YP_668694.1 810697 D 362663 CDS YP_668695.1 110640967 4191077 811389..812447 1 NC_008253.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 812447 modC 4191077 modC Escherichia coli 536 molybdate transporter ATP-binding protein YP_668695.1 811389 D 362663 CDS YP_668696.1 110640968 4191078 complement(812448..813266) 1 NC_008253.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 813266 4191078 ECP_0778 Escherichia coli 536 phosphotransferase YP_668696.1 812448 R 362663 CDS YP_668697.1 110640969 4191079 813421..814416 1 NC_008253.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 814416 4191079 ECP_0779 Escherichia coli 536 6-phosphogluconolactonase YP_668697.1 813421 D 362663 CDS YP_668698.1 110640970 4191080 complement(814457..815215) 1 NC_008253.1 similar to C-terminal transcriptional regulator YbhD; transcriptional regulator 815215 4191080 ECP_0780 Escherichia coli 536 transcriptional regulator YP_668698.1 814457 R 362663 CDS YP_668699.1 110640971 4191081 complement(815233..815472) 1 NC_008253.1 similar to N-terminal transcriptional regulator YbhD; transcriptional regulator 815472 4191081 ECP_0781 Escherichia coli 536 transcriptional regulator YP_668699.1 815233 R 362663 CDS YP_668700.1 110640972 4191082 815593..816645 1 NC_008253.1 hypothetical protein 816645 4191082 ECP_0782 Escherichia coli 536 hypothetical protein YP_668700.1 815593 D 362663 CDS YP_668701.1 110640973 4191083 816721..818154 1 NC_008253.1 membrane transport protein 818154 4191083 ECP_0783 Escherichia coli 536 membrane transport protein YP_668701.1 816721 D 362663 CDS YP_668702.1 110640974 4191084 818337..820598 1 NC_008253.1 hypothetical protein 820598 4191084 ECP_0784 Escherichia coli 536 hypothetical protein YP_668702.1 818337 D 362663 CDS YP_668703.1 110640975 4191085 complement(820739..822022) 1 NC_008253.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase; pectinesterase 822022 4191085 ECP_0785 Escherichia coli 536 pectinesterase YP_668703.1 820739 R 362663 CDS YP_668704.1 110640976 4191086 complement(822174..822650) 1 NC_008253.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 822650 4191086 ECP_0786 Escherichia coli 536 kinase inhibitor protein YP_668704.1 822174 R 362663 CDS YP_668705.1 110640977 4191087 822759..823889 1 NC_008253.1 virulence protein GipA 823889 4191087 ECP_0787 Escherichia coli 536 virulence protein GipA YP_668705.1 822759 D 362663 CDS YP_668706.1 110640978 4191088 complement(824000..825400) 1 NC_008253.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 825400 4191088 ECP_0788 Escherichia coli 536 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_668706.1 824000 R 362663 CDS YP_668707.1 110640979 4191089 825376..826416 1 NC_008253.1 biotin synthase 826416 4191089 ECP_0789 Escherichia coli 536 biotin synthase YP_668707.1 825376 D 362663 CDS YP_668708.1 110640980 4191090 826413..827567 1 NC_008253.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 827567 4191090 ECP_0790 Escherichia coli 536 8-amino-7-oxononanoate synthase YP_668708.1 826413 D 362663 CDS YP_668709.1 110640981 4191091 827554..828309 1 NC_008253.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 828309 4191091 ECP_0791 Escherichia coli 536 biotin biosynthesis protein BioC YP_668709.1 827554 D 362663 CDS YP_668710.1 110640982 4191092 828302..828979 1 NC_008253.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 828979 bioD 4191092 bioD Escherichia coli 536 dithiobiotin synthetase YP_668710.1 828302 D 362663 CDS YP_668711.1 110640983 4189907 829558..831579 1 NC_008253.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 831579 4189907 ECP_0793 Escherichia coli 536 excinuclease ABC subunit B YP_668711.1 829558 D 362663 CDS YP_668712.1 110640984 4189908 complement(831617..832525) 1 NC_008253.1 hypothetical protein 832525 4189908 ECP_0794 Escherichia coli 536 hypothetical protein YP_668712.1 831617 R 362663 CDS YP_668713.1 110640985 4189909 832889..833911 1 NC_008253.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 833911 moaA 4189909 moaA Escherichia coli 536 molybdenum cofactor biosynthesis protein A YP_668713.1 832889 D 362663 CDS YP_668714.1 110640986 4189910 833933..834445 1 NC_008253.1 molybdenum cofactor biosynthesis protein B 834445 4189910 ECP_0796 Escherichia coli 536 molybdenum cofactor biosynthesis protein B YP_668714.1 833933 D 362663 CDS YP_668715.1 110640987 4189911 834448..834933 1 NC_008253.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein C 834933 moaC 4189911 moaC Escherichia coli 536 molybdenum cofactor biosynthesis protein C YP_668715.1 834448 D 362663 CDS YP_668716.1 110640988 4189912 834926..835171 1 NC_008253.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 835171 moaD 4189912 moaD Escherichia coli 536 molybdopterin synthase small subunit YP_668716.1 834926 D 362663 CDS YP_668717.1 110640989 4189913 835173..835625 1 NC_008253.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase large subunit 835625 moaE 4189913 moaE Escherichia coli 536 molybdopterin synthase large subunit YP_668717.1 835173 D 362663 CDS YP_668718.1 110640990 4189914 835762..836466 1 NC_008253.1 hypothetical protein 836466 4189914 ECP_0800 Escherichia coli 536 hypothetical protein YP_668718.1 835762 D 362663 CDS YP_668719.1 110640991 4189915 836672..837385 1 NC_008253.1 hypothetical protein 837385 4189915 ECP_0801 Escherichia coli 536 hypothetical protein YP_668719.1 836672 D 362663 CDS YP_668720.1 110640992 4189916 complement(837421..838377) 1 NC_008253.1 hypothetical protein 838377 4189916 ECP_0802 Escherichia coli 536 hypothetical protein YP_668720.1 837421 R 362663 CDS YP_668721.1 110640993 4189917 complement(838377..839618) 1 NC_008253.1 phospholipase; cardiolipin synthase 2 839618 4189917 ECP_0803 Escherichia coli 536 cardiolipin synthase 2 YP_668721.1 838377 R 362663 CDS YP_668722.1 110640994 4189918 complement(839615..840376) 1 NC_008253.1 hypothetical protein 840376 4189918 ECP_0804 Escherichia coli 536 hypothetical protein YP_668722.1 839615 R 362663 CDS YP_668723.1 110640995 4189919 840509..840919 1 NC_008253.1 hypothetical protein 840919 4189919 ECP_0805 Escherichia coli 536 hypothetical protein YP_668723.1 840509 D 362663 CDS YP_668724.1 110640996 4189920 complement(840881..841987) 1 NC_008253.1 membrane protein YbhR 841987 4189920 ECP_0806 Escherichia coli 536 membrane protein YbhR YP_668724.1 840881 R 362663 CDS YP_668725.1 110640997 4189921 complement(841998..843131) 1 NC_008253.1 inner membrane protein 843131 4189921 ECP_0807 Escherichia coli 536 inner membrane protein YP_668725.1 841998 R 362663 CDS YP_668726.1 110640998 4189922 complement(843124..844860) 1 NC_008253.1 ABC transporter ATP-binding protein 844860 4189922 ECP_0808 Escherichia coli 536 ABC transporter ATP-binding protein YP_668726.1 843124 R 362663 CDS YP_668727.1 110640999 4189923 complement(844853..845848) 1 NC_008253.1 hypothetical protein 845848 4189923 ECP_0809 Escherichia coli 536 hypothetical protein YP_668727.1 844853 R 362663 CDS YP_668728.1 110641000 4189924 complement(845851..846534) 1 NC_008253.1 DNA-binding transcriptional regulator 846534 4189924 ECP_0810 Escherichia coli 536 DNA-binding transcriptional regulator YP_668728.1 845851 R 362663 CDS YP_668729.1 110641001 4189925 846751..848112 1 NC_008253.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 848112 4189925 ECP_0811 Escherichia coli 536 ATP-dependent RNA helicase RhlE YP_668729.1 846751 D 362663 CDS YP_668730.1 110641002 4190101 complement(848345..848650) 1 NC_008253.1 hypothetical protein 848650 4190101 ECP_0812 Escherichia coli 536 hypothetical protein YP_668730.1 848345 R 362663 CDS YP_668731.1 110641003 4190102 848649..850799 1 NC_008253.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 850799 dinG 4190102 dinG Escherichia coli 536 ATP-dependent DNA helicase DinG YP_668731.1 848649 D 362663 CDS YP_668732.1 110641004 4190103 850827..851789 1 NC_008253.1 glycosyl transferase family protein 851789 4190103 ECP_0814 Escherichia coli 536 glycosyl transferase family protein YP_668732.1 850827 D 362663 CDS YP_668733.1 110641005 4190104 851930..853015 1 NC_008253.1 hypothetical protein 853015 4190104 ECP_0815 Escherichia coli 536 hypothetical protein YP_668733.1 851930 D 362663 CDS YP_668734.1 110641006 4190105 complement(853243..853503) 1 NC_008253.1 hypothetical protein 853503 4190105 ECP_0816 Escherichia coli 536 hypothetical protein YP_668734.1 853243 R 362663 CDS YP_668735.1 110641007 4190106 complement(853768..854034) 1 NC_008253.1 hypothetical protein 854034 4190106 ECP_0817 Escherichia coli 536 hypothetical protein YP_668735.1 853768 R 362663 CDS YP_668736.1 110641008 4190107 complement(854108..854785) 1 NC_008253.1 hydroxylase 854785 4190107 ECP_0818 Escherichia coli 536 hydroxylase YP_668736.1 854108 R 362663 CDS YP_668737.1 110641009 4190108 complement(855001..857283) 1 NC_008253.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 857283 4190108 ECP_0819 Escherichia coli 536 catecholate siderophore receptor Fiu YP_668737.1 855001 R 362663 CDS YP_668738.1 110641010 4190109 complement(857548..857808) 1 NC_008253.1 hypothetical protein 857808 4190109 ECP_0820 Escherichia coli 536 hypothetical protein YP_668738.1 857548 R 362663 CDS YP_668739.1 110641011 4190110 858084..859010 1 NC_008253.1 SAM-dependent methyltransferase 859010 4190110 ECP_0821 Escherichia coli 536 SAM-dependent methyltransferase YP_668739.1 858084 D 362663 CDS YP_668740.1 110641012 4190111 complement(859007..861232) 1 NC_008253.1 hypothetical protein 861232 4190111 ECP_0822 Escherichia coli 536 hypothetical protein YP_668740.1 859007 R 362663 CDS YP_668741.1 110641013 4190112 complement(861349..862071) 1 NC_008253.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 862071 glnQ 4190112 glnQ Escherichia coli 536 glutamine ABC transporter ATP-binding protein YP_668741.1 861349 R 362663 CDS YP_668742.1 110641014 4190113 complement(862068..862727) 1 NC_008253.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 862727 glnP 4190113 glnP Escherichia coli 536 glutamine ABC transporter permease YP_668742.1 862068 R 362663 CDS YP_668743.1 110641015 4190114 complement(862866..863612) 1 NC_008253.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 863612 glnH 4190114 glnH Escherichia coli 536 glutamine ABC transporter periplasmic protein YP_668743.1 862866 R 362663 CDS YP_668744.1 110641016 4190115 complement(864016..864519) 1 NC_008253.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 864519 4190115 ECP_0826 Escherichia coli 536 DNA starvation/stationary phase protection protein Dps YP_668744.1 864016 R 362663 CDS YP_668745.1 110641017 4190116 complement(864819..865706) 1 NC_008253.1 threonine and homoserine efflux system 865706 4190116 ECP_0827 Escherichia coli 536 threonine and homoserine efflux system YP_668745.1 864819 R 362663 CDS YP_668746.1 110641018 4190117 866059..866574 1 NC_008253.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 866574 ompX 4190117 ompX Escherichia coli 536 outer membrane protein X YP_668746.1 866059 D 362663 CDS YP_668747.1 110641019 4190118 complement(866624..868207) 1 NC_008253.1 membrane protein YbiP 868207 4190118 ECP_0829 Escherichia coli 536 membrane protein YbiP YP_668747.1 866624 R 362663 CDS YP_668748.1 110641020 4190119 868231..868446 1 NC_008253.1 hypothetical protein 868446 4190119 ECP_0830 Escherichia coli 536 hypothetical protein YP_668748.1 868231 D 362663 CDS YP_668749.1 110641021 4190120 868793..869260 1 NC_008253.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 869260 4190120 ECP_0831 Escherichia coli 536 manganese transport regulator MntR YP_668749.1 868793 D 362663 CDS YP_668750.1 110641022 4189679 869257..870375 1 NC_008253.1 hypothetical protein 870375 4189679 ECP_0832 Escherichia coli 536 hypothetical protein YP_668750.1 869257 D 362663 CDS YP_668751.1 110641023 4189680 complement(870433..871353) 1 NC_008253.1 hypothetical protein 871353 4189680 ECP_0833 Escherichia coli 536 hypothetical protein YP_668751.1 870433 R 362663 CDS YP_668752.1 110641024 4189681 871572..873164 1 NC_008253.1 ABC transporter ATP-binding protein 873164 4189681 ECP_0834 Escherichia coli 536 ABC transporter ATP-binding protein YP_668752.1 871572 D 362663 CDS YP_668753.1 110641025 4189682 complement(873364..874179) 1 NC_008253.1 HAD family hydrolase 874179 4189682 ECP_0835 Escherichia coli 536 HAD family hydrolase YP_668753.1 873364 R 362663 CDS YP_668754.1 110641026 4189683 complement(874325..876757) 1 NC_008253.1 formate acetyltransferase 3 876757 4189683 ECP_0836 Escherichia coli 536 formate acetyltransferase 3 YP_668754.1 874325 R 362663 CDS YP_668755.1 110641027 4189684 complement(876763..877662) 1 NC_008253.1 pyruvate formate-lyase 3 activating enzyme 877662 4189684 ECP_0837 Escherichia coli 536 pyruvate formate-lyase 3 activating enzyme YP_668755.1 876763 R 362663 CDS YP_668756.1 110641028 4189685 877793..878455 1 NC_008253.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 878455 4189685 ECP_0838 Escherichia coli 536 fructose-6-phosphate aldolase YP_668756.1 877793 D 362663 CDS YP_668757.1 110641029 4189686 complement(878531..879280) 1 NC_008253.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 879280 4189686 ECP_0839 Escherichia coli 536 molybdopterin biosynthesis protein MoeB YP_668757.1 878531 R 362663 CDS YP_668758.1 110641030 4189687 complement(879280..880515) 1 NC_008253.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 880515 4189687 ECP_0840 Escherichia coli 536 molybdopterin biosynthesis protein MoeA YP_668758.1 879280 R 362663 CDS YP_668759.1 110641031 4189688 880719..881684 1 NC_008253.1 L-asparaginase 881684 4189688 ECP_0841 Escherichia coli 536 L-asparaginase YP_668759.1 880719 D 362663 CDS YP_668760.1 110641032 4189689 881704..883542 1 NC_008253.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 883542 4189689 ECP_0842 Escherichia coli 536 glutathione transporter ATP-binding protein YP_668760.1 881704 D 362663 CDS YP_668761.1 110644841 4189690 883562..883852 1 NC_008253.1 similar to N-terminal part of binding protein YliB; hypothetical protein 883852 4189690 ECP_0843 Escherichia coli 536 hypothetical protein YP_668761.1 883562 D 362663 CDS YP_668762.1 110644842 4189691 883887..885101 1 NC_008253.1 similar to C-terminal part of binding protein YliB; hypothetical protein 885101 4189691 ECP_0844 Escherichia coli 536 hypothetical protein YP_668762.1 883887 D 362663 CDS YP_668763.1 110641033 4189692 885119..886039 1 NC_008253.1 ABC transporter substrate-binding protein 886039 4189692 ECP_0845 Escherichia coli 536 ABC transporter substrate-binding protein YP_668763.1 885119 D 362663 CDS YP_668764.1 110641034 4189693 886042..886953 1 NC_008253.1 ABC transporter inner membrane component 886953 4189693 ECP_0846 Escherichia coli 536 ABC transporter inner membrane component YP_668764.1 886042 D 362663 CDS YP_668765.1 110641035 4189694 887130..889478 1 NC_008253.1 hypothetical protein 889478 4189694 ECP_0847 Escherichia coli 536 hypothetical protein YP_668765.1 887130 D 362663 CDS YP_668766.1 110641036 4189695 889573..890814 1 NC_008253.1 hypothetical protein 890814 4189695 ECP_0848 Escherichia coli 536 hypothetical protein YP_668766.1 889573 D 362663 CDS YP_668767.1 110641037 4189696 complement(890861..892186) 1 NC_008253.1 hypothetical protein 892186 4189696 ECP_0849 Escherichia coli 536 hypothetical protein YP_668767.1 890861 R 362663 CDS YP_668768.1 110641038 4189697 892399..892782 1 NC_008253.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 892782 bssR 4189697 bssR Escherichia coli 536 biofilm formation regulatory protein BssR YP_668768.1 892399 D 362663 CDS YP_668769.1 110641039 4188903 892893..894008 1 NC_008253.1 hypothetical protein 894008 4188903 ECP_0851 Escherichia coli 536 hypothetical protein YP_668769.1 892893 D 362663 CDS YP_668770.1 110641040 4188904 complement(894005..894631) 1 NC_008253.1 GST-like protein 894631 4188904 ECP_0852 Escherichia coli 536 GST-like protein YP_668770.1 894005 R 362663 CDS YP_668771.1 110641041 4188905 894877..896079 1 NC_008253.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 896079 4188905 ECP_0853 Escherichia coli 536 D-alanyl-D-alanine carboxypeptidase YP_668771.1 894877 D 362663 CDS YP_668772.1 110641042 4188906 complement(896126..896884) 1 NC_008253.1 DNA-binding transcriptional repressor DeoR 896884 4188906 ECP_0854 Escherichia coli 536 DNA-binding transcriptional repressor DeoR YP_668772.1 896126 R 362663 CDS YP_668773.1 110641043 4188907 complement(896942..897538) 1 NC_008253.1 undecaprenyl pyrophosphate phosphatase 897538 4188907 ECP_0855 Escherichia coli 536 undecaprenyl pyrophosphate phosphatase YP_668773.1 896942 R 362663 CDS YP_668774.1 110641044 4188908 897824..899056 1 NC_008253.1 multidrug translocase MmdfA 899056 4188908 ECP_0856 Escherichia coli 536 multidrug translocase MmdfA YP_668774.1 897824 D 362663 CDS YP_668775.1 110641045 4188909 complement(899097..899375) 1 NC_008253.1 hypothetical protein 899375 4188909 ECP_0857 Escherichia coli 536 hypothetical protein YP_668775.1 899097 R 362663 CDS YP_668776.1 110641046 4188910 complement(899467..900282) 1 NC_008253.1 HAD family hydrolase 900282 4188910 ECP_0858 Escherichia coli 536 HAD family hydrolase YP_668776.1 899467 R 362663 CDS YP_668777.1 110641047 4188911 complement(900282..901490) 1 NC_008253.1 membrane protein YbjJ 901490 4188911 ECP_0859 Escherichia coli 536 membrane protein YbjJ YP_668777.1 900282 R 362663 CDS YP_668778.1 110641048 4188912 901574..902110 1 NC_008253.1 transcriptional regulator YbjK 902110 4188912 ECP_0860 Escherichia coli 536 transcriptional regulator YbjK YP_668778.1 901574 D 362663 CDS YP_668779.1 110641049 4188913 complement(902285..903970) 1 NC_008253.1 hypothetical protein 903970 4188913 ECP_0861 Escherichia coli 536 hypothetical protein YP_668779.1 902285 R 362663 CDS YP_668780.1 110641050 4188914 904240..904617 1 NC_008253.1 inner membrane protein YbjM 904617 4188914 ECP_0862 Escherichia coli 536 inner membrane protein YbjM YP_668780.1 904240 D 362663 CDS YP_668781.1 110641051 4188915 complement(904647..904904) 1 NC_008253.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 904904 grxA 4188915 grxA Escherichia coli 536 glutaredoxin YP_668781.1 904647 R 362663 CDS YP_668782.1 110641052 4188916 905064..905351 1 NC_008253.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 905351 4188916 ECP_0864 Escherichia coli 536 hypothetical protein YP_668782.1 905064 D 362663 CDS YP_668783.1 110641053 4188917 905335..906057 1 NC_008253.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 906057 4188917 ECP_0865 Escherichia coli 536 nitroreductase A YP_668783.1 905335 D 362663 CDS YP_668784.1 110641054 4188918 906118..907020 1 NC_008253.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 907020 4188918 ECP_0866 Escherichia coli 536 ribosomal protein S6 modification protein YP_668784.1 906118 D 362663 CDS YP_668785.1 110641055 4188919 907108..907584 1 NC_008253.1 cytoplasmic protein YbjN 907584 4188919 ECP_0867 Escherichia coli 536 cytoplasmic protein YbjN YP_668785.1 907108 D 362663 CDS YP_668786.1 110641056 4188920 907934..909046 1 NC_008253.1 putrescine ABC transporter periplasmic-binding protein 909046 4188920 ECP_0868 Escherichia coli 536 putrescine ABC transporter periplasmic-binding protein YP_668786.1 907934 D 362663 CDS YP_668787.1 110641057 4188921 909060..910274 1 NC_008253.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 910274 potG 4188921 potG Escherichia coli 536 putrescine ABC transporter ATP-binding protein YP_668787.1 909060 D 362663 CDS YP_668788.1 110641058 4188922 910284..911228 1 NC_008253.1 putrescine ABC transporter membrane protein 911228 4188922 ECP_0870 Escherichia coli 536 putrescine ABC transporter membrane protein YP_668788.1 910284 D 362663 CDS YP_668789.1 110641059 4187547 911225..912070 1 NC_008253.1 putrescine ABC transporter membrane protein 912070 4187547 ECP_0871 Escherichia coli 536 putrescine ABC transporter membrane protein YP_668789.1 911225 D 362663 CDS YP_668790.1 110641060 4187548 912130..912618 1 NC_008253.1 hypothetical protein 912618 4187548 ECP_0872 Escherichia coli 536 hypothetical protein YP_668790.1 912130 D 362663 CDS YP_668791.1 110641061 4187549 912659..913786 1 NC_008253.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 913786 rumB 4187549 rumB Escherichia coli 536 23S rRNA methyluridine methyltransferase YP_668791.1 912659 D 362663 CDS YP_668792.1 110641062 4187552 complement(914773..915441) 1 NC_008253.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 915441 artM 4187552 artM Escherichia coli 536 arginine transporter permease subunit ArtM YP_668792.1 914773 R 362663 CDS YP_668793.1 110641063 4187553 complement(915441..916157) 1 NC_008253.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 916157 4187553 ECP_0877 Escherichia coli 536 arginine transporter permease subunit ArtQ YP_668793.1 915441 R 362663 CDS YP_668794.1 110641064 4187554 complement(916164..916895) 1 NC_008253.1 arginine/ornithine ABC transporter substrate-binding protein 916895 4187554 ECP_0878 Escherichia coli 536 arginine/ornithine ABC transporter substrate-binding protein YP_668794.1 916164 R 362663 CDS YP_668795.1 110641065 4187555 complement(916913..917641) 1 NC_008253.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 917641 artP 4187555 artP Escherichia coli 536 arginine transporter ATP-binding subunit YP_668795.1 916913 R 362663 CDS YP_668796.1 110641066 4187556 complement(917859..918374) 1 NC_008253.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 918374 4187556 ECP_0880 Escherichia coli 536 lipoprotein YP_668796.1 917859 R 362663 CDS YP_668797.1 110641067 4187557 918500..918823 1 NC_008253.1 hypothetical protein 918823 4187557 ECP_0881 Escherichia coli 536 hypothetical protein YP_668797.1 918500 D 362663 CDS YP_668798.1 110641068 4187558 918820..919650 1 NC_008253.1 N-acetylmuramoyl-L-alanine amidase 919650 4187558 ECP_0882 Escherichia coli 536 N-acetylmuramoyl-L-alanine amidase YP_668798.1 918820 D 362663 CDS YP_668799.1 110641069 4187559 complement(919647..920696) 1 NC_008253.1 nucleotide di-P-sugar epimerase or dehydratase 920696 4187559 ECP_0883 Escherichia coli 536 nucleotide di-P-sugar epimerase or dehydratase YP_668799.1 919647 R 362663 CDS YP_668800.1 110641070 4187560 complement(920759..922189) 1 NC_008253.1 hypothetical protein 922189 4187560 ECP_0884 Escherichia coli 536 hypothetical protein YP_668800.1 920759 R 362663 CDS YP_668801.1 110641071 4187561 complement(922200..923201) 1 NC_008253.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 923201 4187561 ECP_0885 Escherichia coli 536 L-threonine aldolase YP_668801.1 922200 R 362663 CDS YP_668802.1 110641072 4187562 complement(923238..924956) 1 NC_008253.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 924956 4187562 ECP_0886 Escherichia coli 536 pyruvate dehydrogenase YP_668802.1 923238 R 362663 CDS YP_668803.1 110641073 4187563 complement(925089..926057) 1 NC_008253.1 HCP oxidoreductase 926057 4187563 ECP_0887 Escherichia coli 536 HCP oxidoreductase YP_668803.1 925089 R 362663 CDS YP_668804.1 110641074 4191819 complement(926069..927721) 1 NC_008253.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 927721 4191819 ECP_0888 Escherichia coli 536 hydroxylamine reductase YP_668804.1 926069 R 362663 CDS YP_668805.1 110641075 4191820 complement(927865..928764) 1 NC_008253.1 hypothetical protein 928764 4191820 ECP_0889 Escherichia coli 536 hypothetical protein YP_668805.1 927865 R 362663 CDS YP_668806.1 110641076 4191821 complement(929085..929780) 1 NC_008253.1 major intrinsic protein; porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 929780 4191821 ECP_0890 Escherichia coli 536 aquaporin Z YP_668806.1 929085 R 362663 CDS YP_668807.1 110641077 4191822 930206..931864 1 NC_008253.1 hypothetical protein 931864 4191822 ECP_0891 Escherichia coli 536 hypothetical protein YP_668807.1 930206 D 362663 CDS YP_668808.1 110641078 4191823 complement(931861..932853) 1 NC_008253.1 hypothetical protein 932853 4191823 ECP_0892 Escherichia coli 536 hypothetical protein YP_668808.1 931861 R 362663 CDS YP_668809.1 110641079 4191824 932968..934083 1 NC_008253.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 934083 4191824 ECP_0893 Escherichia coli 536 macrolide transporter subunit MacA YP_668809.1 932968 D 362663 CDS YP_668810.1 110641080 4191825 934080..936026 1 NC_008253.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 936026 4191825 ECP_0894 Escherichia coli 536 macrolide transporter ATP-binding /permease YP_668810.1 934080 D 362663 CDS YP_668811.1 110641081 4191826 complement(936099..936323) 1 NC_008253.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 936323 4191826 ECP_0895 Escherichia coli 536 stationary phase/starvation inducible regulatory protein CspD YP_668811.1 936099 R 362663 CDS YP_668812.1 110641082 4191827 936646..936966 1 NC_008253.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 936966 clpS 4191827 clpS Escherichia coli 536 ATP-dependent Clp protease adaptor protein ClpS YP_668812.1 936646 D 362663 CDS YP_668813.1 110641083 4191828 936997..939273 1 NC_008253.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 939273 clpA 4191828 clpA Escherichia coli 536 ATP-dependent Clp protease ATP-binding subunit YP_668813.1 936997 D 362663 CDS YP_668814.1 110641084 4191829 complement(940017..940235) 1 NC_008253.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 940235 infA 4191829 infA Escherichia coli 536 translation initiation factor IF-1 YP_668814.1 940017 R 362663 CDS YP_668815.1 110641085 4191830 complement(940520..941224) 1 NC_008253.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 941224 aat 4191830 aat Escherichia coli 536 leucyl/phenylalanyl-tRNA--protein transferase YP_668815.1 940520 R 362663 CDS YP_668816.1 110641086 4191831 complement(941266..942987) 1 NC_008253.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 942987 4191831 ECP_0900 Escherichia coli 536 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_668816.1 941266 R 362663 CDS YP_668817.1 110641087 4191832 complement(942988..944754) 1 NC_008253.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 944754 4191832 ECP_0901 Escherichia coli 536 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_668817.1 942988 R 362663 CDS YP_668818.1 110641088 4191833 complement(944877..945842) 1 NC_008253.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 945842 4191833 ECP_0902 Escherichia coli 536 thioredoxin reductase YP_668818.1 944877 R 362663 CDS YP_668819.1 110641089 4191834 946335..946880 1 NC_008253.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 946880 4191834 ECP_0903 Escherichia coli 536 leucine-responsive transcriptional regulator YP_668819.1 946335 D 362663 CDS YP_668820.1 110641090 4191835 947015..950995 1 NC_008253.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 950995 4191835 ECP_0904 Escherichia coli 536 DNA translocase FtsK YP_668820.1 947015 D 362663 CDS YP_668821.1 110641091 4191836 951151..951765 1 NC_008253.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 951765 lolA 4191836 lolA Escherichia coli 536 outer-membrane lipoprotein carrier protein YP_668821.1 951151 D 362663 CDS YP_668822.1 110641092 4191837 951776..953119 1 NC_008253.1 recombination factor protein RarA 953119 4191837 ECP_0906 Escherichia coli 536 recombination factor protein RarA YP_668822.1 951776 D 362663 CDS YP_668823.1 110641093 4187489 953210..954502 1 NC_008253.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 954502 4187489 ECP_0907 Escherichia coli 536 seryl-tRNA synthetase YP_668823.1 953210 D 362663 CDS YP_668824.1 110641094 4187490 954741..957185 1 NC_008253.1 anaerobic dimethyl sulfoxide reductase subunit A 957185 4187490 ECP_0908 Escherichia coli 536 anaerobic dimethyl sulfoxide reductase subunit A YP_668824.1 954741 D 362663 CDS YP_668825.1 110641095 4187491 957196..957813 1 NC_008253.1 anaerobic dimethyl sulfoxide reductase subunit B 957813 4187491 ECP_0909 Escherichia coli 536 anaerobic dimethyl sulfoxide reductase subunit B YP_668825.1 957196 D 362663 CDS YP_668826.1 110641096 4187492 957815..958678 1 NC_008253.1 anaerobic dimethyl sulfoxide reductase subunit C 958678 4187492 ECP_0910 Escherichia coli 536 anaerobic dimethyl sulfoxide reductase subunit C YP_668826.1 957815 D 362663 CDS YP_668827.1 110641097 4187493 complement(958714..959340) 1 NC_008253.1 hydrolase; hypothetical protein 959340 4187493 ECP_0911 Escherichia coli 536 hypothetical protein YP_668827.1 958714 R 362663 CDS YP_668828.1 110641098 4187494 959654..960802 1 NC_008253.1 MFS family transporter protein 960802 4187494 ECP_0912 Escherichia coli 536 MFS family transporter protein YP_668828.1 959654 D 362663 CDS YP_668829.1 110641099 4187495 complement(960899..961639) 1 NC_008253.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 961639 pflA 4187495 pflA Escherichia coli 536 pyruvate formate lyase-activating enzyme 1 YP_668829.1 960899 R 362663 CDS YP_668830.1 110641100 4187496 complement(961831..964113) 1 NC_008253.1 formate acetyltransferase 1 964113 4187496 ECP_0914 Escherichia coli 536 formate acetyltransferase 1 YP_668830.1 961831 R 362663 CDS YP_668831.1 110641101 4187497 complement(964168..965364) 1 NC_008253.1 formate transporter 965364 4187497 ECP_0915 Escherichia coli 536 formate transporter YP_668831.1 964168 R 362663 CDS YP_668832.1 110641102 4187498 complement(965431..967191) 1 NC_008253.1 hypothetical protein 967191 4187498 ECP_0916 Escherichia coli 536 hypothetical protein YP_668832.1 965431 R 362663 CDS YP_668833.1 110641103 4187499 967321..968013 1 NC_008253.1 membrane protein YcaP 968013 4187499 ECP_0917 Escherichia coli 536 membrane protein YcaP YP_668833.1 967321 D 362663 CDS YP_668834.1 110641104 4187500 968212..969300 1 NC_008253.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 969300 4187500 ECP_0918 Escherichia coli 536 phosphoserine aminotransferase YP_668834.1 968212 D 362663 CDS YP_668835.1 110641105 4187501 969371..970654 1 NC_008253.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 970654 4187501 ECP_0919 Escherichia coli 536 3-phosphoshikimate 1-carboxyvinyltransferase YP_668835.1 969371 D 362663 CDS YP_668836.1 110641106 4187502 970815..971588 1 NC_008253.1 metalloprotease YcaL 971588 4187502 ECP_0920 Escherichia coli 536 metalloprotease YcaL YP_668836.1 970815 D 362663 CDS YP_668837.1 110641107 4187503 971761..972444 1 NC_008253.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 972444 cmk 4187503 cmk Escherichia coli 536 cytidylate kinase YP_668837.1 971761 D 362663 CDS YP_668838.1 110641108 4187504 972555..974228 1 NC_008253.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 974228 rpsA 4187504 rpsA Escherichia coli 536 30S ribosomal protein S1 YP_668838.1 972555 D 362663 CDS YP_668839.1 110641109 4187505 974388..974672 1 NC_008253.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 974672 ihfB 4187505 ihfB Escherichia coli 536 integration host factor subunit beta YP_668839.1 974388 D 362663 CDS YP_668840.1 110641110 4187506 974878..977142 1 NC_008253.1 competence-related protein; hypothetical protein 977142 4187506 ECP_0924 Escherichia coli 536 hypothetical protein YP_668840.1 974878 D 362663 CDS YP_668841.1 110641111 4187507 977179..978927 1 NC_008253.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 978927 4187507 ECP_0925 Escherichia coli 536 lipid transporter ATP-binding protein/permease YP_668841.1 977179 D 362663 CDS YP_668842.1 110641112 4187508 978924..979910 1 NC_008253.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 979910 lpxK 4187508 lpxK Escherichia coli 536 tetraacyldisaccharide 4'-kinase YP_668842.1 978924 D 362663 CDS YP_668843.1 110641113 4191592 979947..981179 1 NC_008253.1 hypothetical protein 981179 4191592 ECP_0927 Escherichia coli 536 hypothetical protein YP_668843.1 979947 D 362663 CDS YP_668844.1 110641114 4191593 981231..981413 1 NC_008253.1 hypothetical protein 981413 4191593 ECP_0928 Escherichia coli 536 hypothetical protein YP_668844.1 981231 D 362663 CDS YP_668845.1 110641115 4191594 981410..982156 1 NC_008253.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 982156 4191594 ECP_0929 Escherichia coli 536 3-deoxy-manno-octulosonate cytidylyltransferase YP_668845.1 981410 D 362663 CDS YP_668846.1 110641116 4191595 982310..983203 1 NC_008253.1 hypothetical protein 983203 4191595 ECP_0930 Escherichia coli 536 hypothetical protein YP_668846.1 982310 D 362663 CDS YP_668847.1 110641117 4191596 complement(983180..983959) 1 NC_008253.1 hypothetical protein 983959 4191596 ECP_0931 Escherichia coli 536 hypothetical protein YP_668847.1 983180 R 362663 CDS YP_668848.1 110641118 4191597 984095..984880 1 NC_008253.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 984880 4191597 ECP_0932 Escherichia coli 536 metallothionein SmtA YP_668848.1 984095 D 362663 CDS YP_668849.1 110641119 4191598 984877..986199 1 NC_008253.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 986199 4191598 ECP_0933 Escherichia coli 536 condesin subunit F YP_668849.1 984877 D 362663 CDS YP_668850.1 110641120 4191599 986180..986884 1 NC_008253.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 986884 4191599 ECP_0934 Escherichia coli 536 condesin subunit E YP_668850.1 986180 D 362663 CDS YP_668851.1 110641121 4191600 986884..991344 1 NC_008253.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 991344 mukB 4191600 mukB Escherichia coli 536 cell division protein MukB YP_668851.1 986884 D 362663 CDS YP_668852.1 110641122 4191601 991605..993452 1 NC_008253.1 hypothetical protein 993452 4191601 ECP_0936 Escherichia coli 536 hypothetical protein YP_668852.1 991605 D 362663 CDS YP_668853.1 110641123 4191602 993634..994182 1 NC_008253.1 exported protein YcbK 994182 4191602 ECP_0937 Escherichia coli 536 exported protein YcbK YP_668853.1 993634 D 362663 CDS YP_668854.1 110641124 4191603 994209..994856 1 NC_008253.1 metallo-beta-lactamase; hypothetical protein 994856 4191603 ECP_0938 Escherichia coli 536 hypothetical protein YP_668854.1 994209 D 362663 CDS YP_668855.1 110641125 4191604 complement(994906..996096) 1 NC_008253.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 996096 4191604 ECP_0939 Escherichia coli 536 aromatic amino acid aminotransferase YP_668855.1 994906 R 362663 CDS YP_668856.1 110641126 4191605 complement(996281..997369) 1 NC_008253.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 997369 4191605 ECP_0940 Escherichia coli 536 outer membrane protein F YP_668856.1 996281 R 362663 CDS YP_668857.1 110641127 4191606 complement(997973..999373) 1 NC_008253.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 999373 asnC 4191606 asnC Escherichia coli 536 asparaginyl-tRNA synthetase YP_668857.1 997973 R 362663 CDS YP_668858.1 110641128 4187433 1001009..1003621 1 NC_008253.1 aminopeptidase 1003621 pepN 4187433 pepN Escherichia coli 536 aminopeptidase YP_668858.1 1001009 D 362663 CDS YP_668859.1 110641129 4187434 complement(1003815..1004582) 1 NC_008253.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1004582 ssuB 4187434 ssuB Escherichia coli 536 aliphatic sulfonates transport ATP-binding subunit YP_668859.1 1003815 R 362663 CDS YP_668860.1 110641130 4187435 complement(1004579..1005370) 1 NC_008253.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 1005370 ssuC 4187435 ssuC Escherichia coli 536 alkanesulfonate transporter permease YP_668860.1 1004579 R 362663 CDS YP_668861.1 110641131 4187436 complement(1005382..1006527) 1 NC_008253.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1006527 4187436 ECP_0947 Escherichia coli 536 alkanesulfonate monooxygenase YP_668861.1 1005382 R 362663 CDS YP_668862.1 110641132 4187437 complement(1006524..1007483) 1 NC_008253.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1007483 4187437 ECP_0948 Escherichia coli 536 alkanesulfonate transporter substrate-binding subunit YP_668862.1 1006524 R 362663 CDS YP_668863.1 110641133 4187438 complement(1007476..1008051) 1 NC_008253.1 NAD(P)H-dependent FMN reductase 1008051 4187438 ECP_0949 Escherichia coli 536 NAD(P)H-dependent FMN reductase YP_668863.1 1007476 R 362663 CDS YP_668864.1 110641134 4187439 1008288..1009298 1 NC_008253.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1009298 4187439 ECP_0950 Escherichia coli 536 dihydroorotate dehydrogenase 2 YP_668864.1 1008288 D 362663 CDS YP_668865.1 110641135 4187440 1009472..1010014 1 NC_008253.1 hypothetical protein 1010014 4187440 ECP_0951 Escherichia coli 536 hypothetical protein YP_668865.1 1009472 D 362663 CDS YP_668866.1 110641136 4187441 complement(1010011..1011120) 1 NC_008253.1 iron-sulfur binding protein; hypothetical protein 1011120 4187441 ECP_0952 Escherichia coli 536 hypothetical protein YP_668866.1 1010011 R 362663 CDS YP_668867.1 110641137 4187442 1011218..1013326 1 NC_008253.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1013326 rlmL 4187442 rlmL Escherichia coli 536 23S rRNA m(2)G2445 methyltransferase YP_668867.1 1011218 D 362663 CDS YP_668868.1 110641138 4187443 1013338..1015245 1 NC_008253.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1015245 4187443 ECP_0954 Escherichia coli 536 ABC transporter ATPase YP_668868.1 1013338 D 362663 CDS YP_668869.1 110641139 4187444 1015375..1016628 1 NC_008253.1 inner membrane protein; paraquat-inducible protein A 1016628 4187444 ECP_0955 Escherichia coli 536 paraquat-inducible protein A YP_668869.1 1015375 D 362663 CDS YP_668870.1 110641140 4187445 1016633..1018273 1 NC_008253.1 paraquat-inducible protein B 1018273 4187445 ECP_0956 Escherichia coli 536 paraquat-inducible protein B YP_668870.1 1016633 D 362663 CDS YP_668871.1 110641141 4187446 1018270..1018833 1 NC_008253.1 hypothetical protein 1018833 4187446 ECP_0957 Escherichia coli 536 hypothetical protein YP_668871.1 1018270 D 362663 CDS YP_668872.1 110641142 4187447 1019089..1019256 1 NC_008253.1 ribosome modulation factor 1019256 4187447 ECP_0958 Escherichia coli 536 ribosome modulation factor YP_668872.1 1019089 D 362663 CDS YP_668873.2 162138280 4187448 complement(1019326..1019844) 1 NC_008253.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1019844 4187448 ECP_0959 Escherichia coli 536 3-hydroxydecanoyl-ACP dehydratase YP_668873.2 1019326 R 362663 CDS YP_668874.1 110641144 4187449 complement(1019913..1021673) 1 NC_008253.1 protease La 1021673 4187449 ECP_0960 Escherichia coli 536 protease La YP_668874.1 1019913 R 362663 CDS YP_668875.1 110641145 4187450 1021859..1022311 1 NC_008253.1 hypothetical protein 1022311 4187450 ECP_0961 Escherichia coli 536 hypothetical protein YP_668875.1 1021859 D 362663 CDS YP_668876.1 110641146 4187451 complement(1022387..1023427) 1 NC_008253.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1023427 4187451 ECP_0962 Escherichia coli 536 outer membrane protein A YP_668876.1 1022387 R 362663 CDS YP_668877.1 110641147 4190177 1023629..1023799 1 NC_008253.1 hypothetical protein 1023799 4190177 ECP_0963 Escherichia coli 536 hypothetical protein YP_668877.1 1023629 D 362663 CDS YP_668878.1 110641148 4190178 complement(1023783..1024292) 1 NC_008253.1 SOS cell division inhibitor 1024292 4190178 ECP_0964 Escherichia coli 536 SOS cell division inhibitor YP_668878.1 1023783 R 362663 CDS YP_668879.1 110641149 4190179 1024511..1025140 1 NC_008253.1 hypothetical protein 1025140 4190179 ECP_0965 Escherichia coli 536 hypothetical protein YP_668879.1 1024511 D 362663 CDS YP_668880.1 110641150 4190180 complement(1025103..1027265) 1 NC_008253.1 membrane protein YccS 1027265 4190180 ECP_0966 Escherichia coli 536 membrane protein YccS YP_668880.1 1025103 R 362663 CDS YP_668881.1 110641151 4190181 complement(1027275..1027721) 1 NC_008253.1 hypothetical protein 1027721 4190181 ECP_0967 Escherichia coli 536 hypothetical protein YP_668881.1 1027275 R 362663 CDS YP_668882.1 110641152 4190182 1027751..1029898 1 NC_008253.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1029898 helD 4190182 helD Escherichia coli 536 DNA helicase IV YP_668882.1 1027751 D 362663 CDS YP_668883.1 110641153 4190183 complement(1029930..1030397) 1 NC_008253.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1030397 mgsA 4190183 mgsA Escherichia coli 536 methylglyoxal synthase YP_668883.1 1029930 R 362663 CDS YP_668884.1 110641154 4190184 complement(1030484..1031146) 1 NC_008253.1 hypothetical protein 1031146 4190184 ECP_0970 Escherichia coli 536 hypothetical protein YP_668884.1 1030484 R 362663 CDS YP_668885.1 110641155 4190185 1031319..1031732 1 NC_008253.1 succinyl-CoA synthetase; hypothetical protein 1031732 4190185 ECP_0971 Escherichia coli 536 hypothetical protein YP_668885.1 1031319 D 362663 CDS YP_668886.1 110641156 4190186 complement(1031777..1032145) 1 NC_008253.1 hypothetical protein 1032145 4190186 ECP_0972 Escherichia coli 536 hypothetical protein YP_668886.1 1031777 R 362663 CDS YP_668887.1 110641157 4190187 complement(1032152..1033342) 1 NC_008253.1 hypothetical protein 1033342 4190187 ECP_0973 Escherichia coli 536 hypothetical protein YP_668887.1 1032152 R 362663 CDS YP_668888.1 110641158 4190188 1033437..1033715 1 NC_008253.1 acylphosphatase 1033715 4190188 ECP_0974 Escherichia coli 536 acylphosphatase YP_668888.1 1033437 D 362663 CDS YP_668889.1 110641159 4190189 complement(1033712..1034041) 1 NC_008253.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1034041 4190189 ECP_0975 Escherichia coli 536 sulfur transfer protein TusE YP_668889.1 1033712 R 362663 CDS YP_668890.1 110641160 4190190 complement(1034133..1034792) 1 NC_008253.1 hypothetical protein 1034792 4190190 ECP_0976 Escherichia coli 536 hypothetical protein YP_668890.1 1034133 R 362663 CDS YP_668891.1 110641161 4190191 1035513..1036631 1 NC_008253.1 hydrogenase-1 small chain 1036631 4190191 ECP_0977 Escherichia coli 536 hydrogenase-1 small chain YP_668891.1 1035513 D 362663 CDS YP_668892.1 110641162 4190192 1036628..1038421 1 NC_008253.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1038421 4190192 ECP_0978 Escherichia coli 536 hydrogenase 1 large subunit YP_668892.1 1036628 D 362663 CDS YP_668893.1 110641163 4190193 1038440..1039147 1 NC_008253.1 hydrogenase 1 b-type cytochrome subunit 1039147 4190193 ECP_0979 Escherichia coli 536 hydrogenase 1 b-type cytochrome subunit YP_668893.1 1038440 D 362663 CDS YP_668894.1 110641164 4190194 1039144..1039731 1 NC_008253.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1039731 4190194 ECP_0980 Escherichia coli 536 hydrogenase 1 maturation protease YP_668894.1 1039144 D 362663 CDS YP_668895.1 110641165 4190195 1039728..1040126 1 NC_008253.1 involved in processing hydrogenases HyaA and HyaB; hydrogenase-1 operon protein HyaE 1040126 4190195 ECP_0981 Escherichia coli 536 hydrogenase-1 operon protein HyaE YP_668895.1 1039728 D 362663 CDS YP_668896.1 110641166 4190196 1040123..1040980 1 NC_008253.1 hydrogenase-1 operon protein HyaF 1040980 4190196 ECP_0982 Escherichia coli 536 hydrogenase-1 operon protein HyaF YP_668896.1 1040123 D 362663 CDS YP_668897.1 110641167 4187793 1041114..1042658 1 NC_008253.1 cytochrome bd-II oxidase subunit I 1042658 4187793 ECP_0983 Escherichia coli 536 cytochrome bd-II oxidase subunit I YP_668897.1 1041114 D 362663 CDS YP_668898.1 110641168 4187794 1042670..1043806 1 NC_008253.1 cytochrome bd-II oxidase subunit II 1043806 4187794 ECP_0984 Escherichia coli 536 cytochrome bd-II oxidase subunit II YP_668898.1 1042670 D 362663 CDS YP_668899.1 110641169 4187795 1043961..1045301 1 NC_008253.1 phosphoanhydride phosphorylase 1045301 4187795 ECP_0985 Escherichia coli 536 phosphoanhydride phosphorylase YP_668899.1 1043961 D 362663 CDS YP_668900.1 110641170 4187796 complement(1045289..1045501) 1 NC_008253.1 cold shock-like protein CspH 1045501 4187796 ECP_0986 Escherichia coli 536 cold shock-like protein CspH YP_668900.1 1045289 R 362663 CDS YP_668901.1 110641171 4187797 1045787..1045999 1 NC_008253.1 cold shock protein CspG 1045999 4187797 ECP_0987 Escherichia coli 536 cold shock protein CspG YP_668901.1 1045787 D 362663 CDS YP_668902.1 110641172 4187798 1045965..1046198 1 NC_008253.1 hypothetical protein 1046198 4187798 ECP_0988 Escherichia coli 536 hypothetical protein YP_668902.1 1045965 D 362663 CDS YP_668903.1 110641173 4187799 1046393..1046566 1 NC_008253.1 hypothetical protein 1046566 4187799 ECP_0989 Escherichia coli 536 hypothetical protein YP_668903.1 1046393 D 362663 CDS YP_668904.1 110641174 4187800 complement(1046615..1047688) 1 NC_008253.1 electron transport protein YccM 1047688 4187800 ECP_0990 Escherichia coli 536 electron transport protein YccM YP_668904.1 1046615 R 362663 CDS YP_668905.1 110641175 4187801 complement(1047771..1050503) 1 NC_008253.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1050503 4187801 ECP_0991 Escherichia coli 536 hybrid sensory histidine kinase TorS YP_668905.1 1047771 R 362663 CDS YP_668906.1 110641176 4187802 1050586..1051614 1 NC_008253.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1051614 4187802 ECP_0992 Escherichia coli 536 TMAO reductase system periplasmic protein TorT YP_668906.1 1050586 D 362663 CDS YP_668907.1 110641177 4187803 complement(1051587..1052279) 1 NC_008253.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1052279 4187803 ECP_0993 Escherichia coli 536 DNA-binding transcriptional regulator TorR YP_668907.1 1051587 R 362663 CDS YP_668908.1 110641178 4187804 1052409..1053581 1 NC_008253.1 cytochrome c-type protein TorC 1053581 4187804 ECP_0994 Escherichia coli 536 cytochrome c-type protein TorC YP_668908.1 1052409 D 362663 CDS YP_668909.1 110641179 4187805 1053581..1056127 1 NC_008253.1 trimethylamine-N-oxide reductase 1 1056127 4187805 ECP_0995 Escherichia coli 536 trimethylamine-N-oxide reductase 1 YP_668909.1 1053581 D 362663 CDS YP_668910.1 110641180 4187806 1056124..1056723 1 NC_008253.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1056723 torD 4187806 torD Escherichia coli 536 chaperone protein TorD YP_668910.1 1056124 D 362663 CDS YP_668911.1 110641181 4187807 1056806..1057327 1 NC_008253.1 insertion element (orfA) 1057327 4187807 ECP_0997 Escherichia coli 536 insertion element (orfA) YP_668911.1 1056806 D 362663 CDS YP_668912.1 110641182 4187808 1057552..1058154 1 NC_008253.1 insertion element (orfB) 1058154 4187808 ECP_0998 Escherichia coli 536 insertion element (orfB) YP_668912.1 1057552 D 362663 CDS YP_668913.1 110641183 4187809 complement(1058413..1058718) 1 NC_008253.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1058718 4187809 ECP_0999 Escherichia coli 536 chaperone-modulator protein CbpM YP_668913.1 1058413 R 362663 CDS YP_668914.1 110641184 4187810 complement(1058718..1059638) 1 NC_008253.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1059638 4187810 ECP_1000 Escherichia coli 536 curved DNA-binding protein CbpA YP_668914.1 1058718 R 362663 CDS YP_668915.1 110641185 4187811 1060173..1061414 1 NC_008253.1 glucose-1-phosphatase/inositol phosphatase 1061414 4187811 ECP_1001 Escherichia coli 536 glucose-1-phosphatase/inositol phosphatase YP_668915.1 1060173 D 362663 CDS YP_668916.1 110641186 4187773 complement(1061452..1061679) 1 NC_008253.1 hypothetical protein 1061679 4187773 ECP_1002 Escherichia coli 536 hypothetical protein YP_668916.1 1061452 R 362663 CDS YP_668917.1 110641187 4187774 complement(1061700..1062296) 1 NC_008253.1 Trp repressor binding protein; stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1062296 4187774 ECP_1003 Escherichia coli 536 TrpR binding protein WrbA YP_668917.1 1061700 R 362663 CDS YP_668918.1 110641188 4187775 1062669..1062842 1 NC_008253.1 hypothetical protein 1062842 4187775 ECP_1004 Escherichia coli 536 hypothetical protein YP_668918.1 1062669 D 362663 CDS YP_668919.1 110641189 4187776 complement(1062925..1064253) 1 NC_008253.1 purine permease; transporter 1064253 4187776 ECP_1005 Escherichia coli 536 transporter YP_668919.1 1062925 R 362663 CDS YP_668920.1 110641190 4187777 complement(1064274..1064768) 1 NC_008253.1 flavin:NADH reductase YcdH 1064768 4187777 ECP_1006 Escherichia coli 536 flavin:NADH reductase YcdH YP_668920.1 1064274 R 362663 CDS YP_668921.1 110641191 4187778 complement(1064779..1065369) 1 NC_008253.1 hypothetical protein 1065369 4187778 ECP_1007 Escherichia coli 536 hypothetical protein YP_668921.1 1064779 R 362663 CDS YP_668922.1 110641192 4187779 complement(1065379..1066179) 1 NC_008253.1 hydrolase; hypothetical protein 1066179 4187779 ECP_1008 Escherichia coli 536 hypothetical protein YP_668922.1 1065379 R 362663 CDS YP_668923.1 110641193 4187780 complement(1066187..1066573) 1 NC_008253.1 hypothetical endoribonuclease; hypothetical protein 1066573 4187780 ECP_1009 Escherichia coli 536 hypothetical protein YP_668923.1 1066187 R 362663 CDS YP_668924.1 110641194 4187781 complement(1066585..1067277) 1 NC_008253.1 isochorismatase YcdL 1067277 4187781 ECP_1010 Escherichia coli 536 isochorismatase YcdL YP_668924.1 1066585 R 362663 CDS YP_668925.1 110641195 4187782 complement(1067277..1068368) 1 NC_008253.1 monooxygenase YcdM 1068368 4187782 ECP_1011 Escherichia coli 536 monooxygenase YcdM YP_668925.1 1067277 R 362663 CDS YP_668926.1 110641196 4187783 1068655..1069293 1 NC_008253.1 TetR family transcriptional regulator 1069293 4187783 ECP_1012 Escherichia coli 536 TetR family transcriptional regulator YP_668926.1 1068655 D 362663 CDS YP_668927.1 110641197 4187784 complement(1069333..1073295) 1 NC_008253.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1073295 putA 4187784 putA Escherichia coli 536 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_668927.1 1069333 R 362663 CDS YP_668928.1 110641198 4187785 1073353..1073559 1 NC_008253.1 hypothetical protein 1073559 4187785 ECP_1014 Escherichia coli 536 hypothetical protein YP_668928.1 1073353 D 362663 CDS YP_668929.1 110641199 4187786 1073718..1075226 1 NC_008253.1 sodium/proline symporter 1075226 4187786 ECP_1015 Escherichia coli 536 sodium/proline symporter YP_668929.1 1073718 D 362663 CDS YP_668930.1 110641200 4187787 1075446..1076276 1 NC_008253.1 iron permease; hypothetical protein 1076276 4187787 ECP_1016 Escherichia coli 536 hypothetical protein YP_668930.1 1075446 D 362663 CDS YP_668931.1 110641201 4187788 1076334..1077461 1 NC_008253.1 hypothetical protein 1077461 4187788 ECP_1017 Escherichia coli 536 hypothetical protein YP_668931.1 1076334 D 362663 CDS YP_668932.1 110641202 4187789 1077467..1078738 1 NC_008253.1 hypothetical protein 1078738 4187789 ECP_1018 Escherichia coli 536 hypothetical protein YP_668932.1 1077467 D 362663 CDS YP_668933.1 110641203 4187790 1079089..1080153 1 NC_008253.1 hypothetical protein 1080153 4187790 ECP_1019 Escherichia coli 536 hypothetical protein YP_668933.1 1079089 D 362663 CDS YP_668934.1 110641204 4187791 complement(1080203..1080616) 1 NC_008253.1 hypothetical protein 1080616 4187791 ECP_1020 Escherichia coli 536 hypothetical protein YP_668934.1 1080203 R 362663 CDS YP_668935.1 110641205 4187792 complement(1080618..1081856) 1 NC_008253.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; N-glycosyltransferase PgaC 1081856 4187792 ECP_1021 Escherichia coli 536 N-glycosyltransferase PgaC YP_668935.1 1080618 R 362663 CDS YP_668936.1 110641206 4189411 complement(1081936..1083954) 1 NC_008253.1 lipoprotein YcdR 1083954 4189411 ECP_1022 Escherichia coli 536 lipoprotein YcdR YP_668936.1 1081936 R 362663 CDS YP_668937.1 110641207 4189412 complement(1083963..1086386) 1 NC_008253.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1086386 pgaA 4189412 pgaA Escherichia coli 536 outer membrane protein PgaA YP_668937.1 1083963 R 362663 CDS YP_668938.1 110641208 4189413 1086973..1088340 1 NC_008253.1 hypothetical protein 1088340 4189413 ECP_1024 Escherichia coli 536 hypothetical protein YP_668938.1 1086973 D 362663 CDS YP_668939.1 110641209 4189414 1088765..1089703 1 NC_008253.1 2-hydroxyacid dehydrogenase 1089703 4189414 ECP_1025 Escherichia coli 536 2-hydroxyacid dehydrogenase YP_668939.1 1088765 D 362663 CDS YP_668940.1 110641210 4189415 1089758..1090495 1 NC_008253.1 histidinol phosphatase and related hydrolases of the PHP family; hydrolase 1090495 4189415 ECP_1026 Escherichia coli 536 hydrolase YP_668940.1 1089758 D 362663 CDS YP_668941.1 110641211 4189416 1090519..1091073 1 NC_008253.1 hypothetical protein 1091073 4189416 ECP_1027 Escherichia coli 536 hypothetical protein YP_668941.1 1090519 D 362663 CDS YP_668942.1 110641212 4189417 1091144..1091665 1 NC_008253.1 hypothetical protein 1091665 4189417 ECP_1028 Escherichia coli 536 hypothetical protein YP_668942.1 1091144 D 362663 CDS YP_668943.1 110641213 4189418 complement(1091729..1092415) 1 NC_008253.1 curli production assembly/transport component CsgG 1092415 4189418 ECP_1029 Escherichia coli 536 curli production assembly/transport component CsgG YP_668943.1 1091729 R 362663 CDS YP_668944.1 110641214 4189419 complement(1092590..1093006) 1 NC_008253.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1093006 4189419 ECP_1030 Escherichia coli 536 curli assembly protein CsgF YP_668944.1 1092590 R 362663 CDS YP_668945.1 110641215 4189420 complement(1093031..1093420) 1 NC_008253.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1093420 4189420 ECP_1031 Escherichia coli 536 curli assembly protein CsgE YP_668945.1 1093031 R 362663 CDS YP_668946.1 110641216 4189421 complement(1093425..1094075) 1 NC_008253.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1094075 4189421 ECP_1032 Escherichia coli 536 DNA-binding transcriptional regulator CsgD YP_668946.1 1093425 R 362663 CDS YP_668947.1 110641217 4189422 complement(1094487..1094735) 1 NC_008253.1 hypothetical protein 1094735 4189422 ECP_1033 Escherichia coli 536 hypothetical protein YP_668947.1 1094487 R 362663 CDS YP_668948.1 110641218 4189423 1094829..1095284 1 NC_008253.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1095284 4189423 ECP_1034 Escherichia coli 536 curlin minor subunit YP_668948.1 1094829 D 362663 CDS YP_668949.1 110641219 4189424 1095325..1095783 1 NC_008253.1 cryptic curlin major subunit 1095783 4189424 ECP_1035 Escherichia coli 536 cryptic curlin major subunit YP_668949.1 1095325 D 362663 CDS YP_668950.1 110641220 4189425 1095842..1096174 1 NC_008253.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1096174 csgC 4189425 csgC Escherichia coli 536 autoagglutination protein YP_668950.1 1095842 D 362663 CDS YP_668951.1 110641221 4189426 1096295..1096606 1 NC_008253.1 hypothetical protein 1096606 4189426 ECP_1037 Escherichia coli 536 hypothetical protein YP_668951.1 1096295 D 362663 CDS YP_668952.1 110641222 4189427 1096701..1097234 1 NC_008253.1 hypothetical protein 1097234 4189427 ECP_1038 Escherichia coli 536 hypothetical protein YP_668952.1 1096701 D 362663 CDS YP_668953.1 110641223 4189428 1097176..1098657 1 NC_008253.1 hypothetical protein 1098657 4189428 ECP_1039 Escherichia coli 536 hypothetical protein YP_668953.1 1097176 D 362663 CDS YP_668954.1 110641224 4189429 complement(1098665..1099822) 1 NC_008253.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1099822 mdoC 4189429 mdoC Escherichia coli 536 glucans biosynthesis protein YP_668954.1 1098665 R 362663 CDS YP_668955.1 110641225 4189698 1100216..1101751 1 NC_008253.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1101751 mdoG 4189698 mdoG Escherichia coli 536 glucan biosynthesis protein G YP_668955.1 1100216 D 362663 CDS YP_668956.1 110641226 4189699 1101744..1104287 1 NC_008253.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1104287 4189699 ECP_1042 Escherichia coli 536 glucosyltransferase MdoH YP_668956.1 1101744 D 362663 CDS YP_668957.1 110641227 4189700 1104296..1104520 1 NC_008253.1 hypothetical protein 1104520 4189700 ECP_1043 Escherichia coli 536 hypothetical protein YP_668957.1 1104296 D 362663 CDS YP_668958.1 110641228 4189701 1104459..1104686 1 NC_008253.1 hypothetical protein 1104686 4189701 ECP_1044 Escherichia coli 536 hypothetical protein YP_668958.1 1104459 D 362663 CDS YP_668959.1 110641229 4189702 complement(1104687..1105061) 1 NC_008253.1 hypothetical protein 1105061 4189702 ECP_1045 Escherichia coli 536 hypothetical protein YP_668959.1 1104687 R 362663 CDS YP_668960.1 110641230 4189703 complement(1105144..1106370) 1 NC_008253.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1106370 4189703 ECP_1046 Escherichia coli 536 drug efflux system protein MdtG YP_668960.1 1105144 R 362663 CDS YP_668961.1 110641231 4189704 complement(1106542..1107462) 1 NC_008253.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1107462 4189704 ECP_1047 Escherichia coli 536 lipid A biosynthesis lauroyl acyltransferase YP_668961.1 1106542 R 362663 CDS YP_668962.1 110641232 4189705 1107687..1108739 1 NC_008253.1 hypothetical protein 1108739 4189705 ECP_1048 Escherichia coli 536 hypothetical protein YP_668962.1 1107687 D 362663 CDS YP_668963.1 110641233 4189706 complement(1108781..1109356) 1 NC_008253.1 secreted protein; hypothetical protein 1109356 4189706 ECP_1049 Escherichia coli 536 hypothetical protein YP_668963.1 1108781 R 362663 CDS YP_668964.1 110641234 4189707 complement(1109360..1109926) 1 NC_008253.1 cytochrome b561-like protein 2 1109926 4189707 ECP_1050 Escherichia coli 536 cytochrome b561-like protein 2 YP_668964.1 1109360 R 362663 CDS YP_668965.1 110641235 4189708 complement(1110348..1111466) 1 NC_008253.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1111466 solA 4189708 solA Escherichia coli 536 N-methyltryptophan oxidase YP_668965.1 1110348 R 362663 CDS YP_668966.1 110641236 4189709 complement(1111581..1111835) 1 NC_008253.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1111835 bssS 4189709 bssS Escherichia coli 536 biofilm formation regulatory protein BssS YP_668966.1 1111581 R 362663 CDS YP_668967.1 110641237 4189710 complement(1112125..1112370) 1 NC_008253.1 DNA damage-inducible protein I 1112370 4189710 ECP_1053 Escherichia coli 536 DNA damage-inducible protein I YP_668967.1 1112125 R 362663 CDS YP_668968.1 110641238 4189711 complement(1112444..1113490) 1 NC_008253.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1113490 4189711 ECP_1054 Escherichia coli 536 dihydroorotase YP_668968.1 1112444 R 362663 CDS YP_668969.1 110641239 4189712 complement(1113596..1114156) 1 NC_008253.1 hypothetical protein 1114156 4189712 ECP_1055 Escherichia coli 536 hypothetical protein YP_668969.1 1113596 R 362663 CDS YP_668970.1 110641240 4189713 complement(1114290..1114937) 1 NC_008253.1 cofactor involved in the reduction of disulfides; glutaredoxin 1114937 4189713 ECP_1056 Escherichia coli 536 glutaredoxin YP_668970.1 1114290 R 362663 CDS YP_668971.1 110641241 4189714 complement(1115001..1116209) 1 NC_008253.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1116209 4189714 ECP_1057 Escherichia coli 536 multidrug resistance protein MdtH YP_668971.1 1115001 R 362663 CDS YP_668972.1 110641242 4189715 1116445..1117029 1 NC_008253.1 ribosomal-protein-S5-alanine N-acetyltransferase 1117029 4189715 ECP_1058 Escherichia coli 536 ribosomal-protein-S5-alanine N-acetyltransferase YP_668972.1 1116445 D 362663 CDS YP_668973.1 110641243 4189716 1117040..1117687 1 NC_008253.1 hypothetical protein 1117687 4189716 ECP_1059 Escherichia coli 536 hypothetical protein YP_668973.1 1117040 D 362663 CDS YP_668974.1 110641244 4189717 1117689..1118612 1 NC_008253.1 virulence factor MviM 1118612 4189717 ECP_1060 Escherichia coli 536 virulence factor MviM YP_668974.1 1117689 D 362663 CDS YP_668975.1 110641245 4187603 1118722..1120257 1 NC_008253.1 virulence factor mviN-like protein 1120257 4187603 ECP_1061 Escherichia coli 536 virulence factor mviN-like protein YP_668975.1 1118722 D 362663 CDS YP_668976.1 110641246 4187604 complement(1120297..1120713) 1 NC_008253.1 flagellar synthesis protein FlgN 1120713 4187604 ECP_1062 Escherichia coli 536 flagellar synthesis protein FlgN YP_668976.1 1120297 R 362663 CDS YP_668977.1 110641247 4187605 complement(1120718..1121011) 1 NC_008253.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1121011 4187605 ECP_1063 Escherichia coli 536 anti-sigma-28 factor FlgM YP_668977.1 1120718 R 362663 CDS YP_668978.1 110641248 4187606 complement(1121087..1121746) 1 NC_008253.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1121746 flgA 4187606 flgA Escherichia coli 536 flagellar basal body P-ring biosynthesis protein FlgA YP_668978.1 1121087 R 362663 CDS YP_668979.1 110641249 4187607 1121901..1122317 1 NC_008253.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1122317 flgB 4187607 flgB Escherichia coli 536 flagellar basal-body rod protein FlgB YP_668979.1 1121901 D 362663 CDS YP_668980.1 110641250 4187608 1122321..1122725 1 NC_008253.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1122725 flgC 4187608 flgC Escherichia coli 536 flagellar basal body rod protein FlgC YP_668980.1 1122321 D 362663 CDS YP_668981.1 110641251 4187609 1122737..1123432 1 NC_008253.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1123432 flgD 4187609 flgD Escherichia coli 536 flagellar basal body rod modification protein YP_668981.1 1122737 D 362663 CDS YP_668982.1 110641252 4187610 1123457..1124662 1 NC_008253.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1124662 flgE 4187610 flgE Escherichia coli 536 flagellar hook protein FlgE YP_668982.1 1123457 D 362663 CDS YP_668983.1 110641253 4187611 1124682..1125437 1 NC_008253.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1125437 flgF 4187611 flgF Escherichia coli 536 flagellar basal body rod protein FlgF YP_668983.1 1124682 D 362663 CDS YP_668984.1 110641254 4187612 1125609..1126391 1 NC_008253.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1126391 flgG 4187612 flgG Escherichia coli 536 flagellar basal body rod protein FlgG YP_668984.1 1125609 D 362663 CDS YP_668985.1 110641255 4187613 1126435..1127142 1 NC_008253.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1127142 flgH 4187613 flgH Escherichia coli 536 flagellar basal body L-ring protein YP_668985.1 1126435 D 362663 CDS YP_668986.1 110641256 4187614 1127154..1128251 1 NC_008253.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1128251 flgI 4187614 flgI Escherichia coli 536 flagellar basal body P-ring biosynthesis protein FlgA YP_668986.1 1127154 D 362663 CDS YP_668987.2 162138279 4187615 1128251..1129192 1 NC_008253.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1129192 flgJ 4187615 flgJ Escherichia coli 536 flagellar rod assembly protein/muramidase FlgJ YP_668987.2 1128251 D 362663 CDS YP_668988.1 110641258 4187616 1129258..1130901 1 NC_008253.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1130901 flgK 4187616 flgK Escherichia coli 536 flagellar hook-associated protein FlgK YP_668988.1 1129258 D 362663 CDS YP_668989.1 110641259 4187617 1130913..1131866 1 NC_008253.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1131866 flgL 4187617 flgL Escherichia coli 536 flagellar hook-associated protein FlgL YP_668989.1 1130913 D 362663 CDS YP_668990.1 110641260 4187618 complement(1132061..1135246) 1 NC_008253.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1135246 rne 4187618 rne Escherichia coli 536 ribonuclease E YP_668990.1 1132061 R 362663 CDS YP_668991.1 110641261 4187619 1135381..1135701 1 NC_008253.1 hypothetical protein 1135701 4187619 ECP_1077 Escherichia coli 536 hypothetical protein YP_668991.1 1135381 D 362663 CDS YP_668992.1 110641262 4187620 1135819..1136778 1 NC_008253.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1136778 4187620 ECP_1078 Escherichia coli 536 23S rRNA pseudouridylate synthase C YP_668992.1 1135819 D 362663 CDS YP_668993.1 110641263 4187621 complement(1136890..1137513) 1 NC_008253.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1137513 4187621 ECP_1079 Escherichia coli 536 Maf-like protein YP_668993.1 1136890 R 362663 CDS YP_668994.1 110641264 4187284 1137673..1138194 1 NC_008253.1 hypothetical protein 1138194 4187284 ECP_1080 Escherichia coli 536 hypothetical protein YP_668994.1 1137673 D 362663 CDS YP_668995.1 110641265 4187285 1138246..1138419 1 NC_008253.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1138419 rpmF 4187285 rpmF Escherichia coli 536 50S ribosomal protein L32 YP_668995.1 1138246 D 362663 CDS YP_668996.1 110641266 4187286 1138500..1139570 1 NC_008253.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1139570 4187286 ECP_1082 Escherichia coli 536 glycerol-3-phosphate acyltransferase PlsX YP_668996.1 1138500 D 362663 CDS YP_668997.1 110641267 4187287 1139638..1140591 1 NC_008253.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1140591 4187287 ECP_1083 Escherichia coli 536 3-oxoacyl-ACP synthase YP_668997.1 1139638 D 362663 CDS YP_668998.1 110641268 4187288 1140607..1141536 1 NC_008253.1 malonyl CoA-acyl carrier protein transacylase 1141536 4187288 ECP_1084 Escherichia coli 536 malonyl CoA-acyl carrier protein transacylase YP_668998.1 1140607 D 362663 CDS YP_668999.1 110641269 4187289 1141549..1142283 1 NC_008253.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1142283 fabG 4187289 fabG Escherichia coli 536 3-ketoacyl-ACP reductase YP_668999.1 1141549 D 362663 CDS YP_669000.1 110641270 4187290 1142494..1142730 1 NC_008253.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1142730 acpP 4187290 acpP Escherichia coli 536 acyl carrier protein YP_669000.1 1142494 D 362663 CDS YP_669001.1 110641271 4187291 1142817..1144058 1 NC_008253.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1144058 4187291 ECP_1087 Escherichia coli 536 3-oxoacyl-ACP synthase YP_669001.1 1142817 D 362663 CDS YP_669002.1 110641272 4187292 1144178..1144987 1 NC_008253.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1144987 4187292 ECP_1088 Escherichia coli 536 4-amino-4-deoxychorismate lyase YP_669002.1 1144178 D 362663 CDS YP_669003.1 110641273 4187293 1144990..1146012 1 NC_008253.1 4-amino-4-deoxychorismate lyase; hypothetical protein 1146012 4187293 ECP_1089 Escherichia coli 536 hypothetical protein YP_669003.1 1144990 D 362663 CDS YP_669004.1 110641274 4187294 1146002..1146643 1 NC_008253.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1146643 tmk 4187294 tmk Escherichia coli 536 thymidylate kinase YP_669004.1 1146002 D 362663 CDS YP_669005.1 110641275 4187295 1146640..1147644 1 NC_008253.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1147644 4187295 ECP_1091 Escherichia coli 536 DNA polymerase III subunit delta' YP_669005.1 1146640 D 362663 CDS YP_669006.1 110641276 4187296 1147655..1148452 1 NC_008253.1 metallodependent hydrolase 1148452 4187296 ECP_1092 Escherichia coli 536 metallodependent hydrolase YP_669006.1 1147655 D 362663 CDS YP_669007.1 110641277 4187297 1148747..1150180 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; glucose-specific PTS system IIBC components 1150180 4187297 ECP_1093 Escherichia coli 536 glucose-specific PTS system IIBC components YP_669007.1 1148747 D 362663 CDS YP_669008.1 110641278 4187298 complement(1150240..1152219) 1 NC_008253.1 ferric-rhodotorulic acid outer membrane transporter 1152219 4187298 ECP_1094 Escherichia coli 536 ferric-rhodotorulic acid outer membrane transporter YP_669008.1 1150240 R 362663 CDS YP_669009.1 110641279 4187299 1152764..1153123 1 NC_008253.1 purine nucleoside phosphoramidase 1153123 4187299 ECP_1095 Escherichia coli 536 purine nucleoside phosphoramidase YP_669009.1 1152764 D 362663 CDS YP_669010.1 110641280 4187300 1153126..1153503 1 NC_008253.1 outer membrane lipoprotein YcfL 1153503 4187300 ECP_1096 Escherichia coli 536 outer membrane lipoprotein YcfL YP_669010.1 1153126 D 362663 CDS YP_669011.1 110641281 4187301 1153517..1154158 1 NC_008253.1 hypothetical protein 1154158 4187301 ECP_1097 Escherichia coli 536 hypothetical protein YP_669011.1 1153517 D 362663 CDS YP_669012.1 110641282 4187302 1154139..1154963 1 NC_008253.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1154963 thiK 4187302 thiK Escherichia coli 536 thiamine kinase YP_669012.1 1154139 D 362663 CDS YP_669013.1 110641283 4187303 1154986..1155999 1 NC_008253.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1155999 4187303 ECP_1099 Escherichia coli 536 beta-hexosaminidase YP_669013.1 1154986 D 362663 CDS YP_669014.1 110641284 4190820 1156022..1156564 1 NC_008253.1 hypothetical protein 1156564 4190820 ECP_1100 Escherichia coli 536 hypothetical protein YP_669014.1 1156022 D 362663 CDS YP_669015.1 110641285 4190821 1156964..1158268 1 NC_008253.1 NADH dehydrogenase 1158268 4190821 ECP_1101 Escherichia coli 536 NADH dehydrogenase YP_669015.1 1156964 D 362663 CDS YP_669016.1 110641286 4190822 1158495..1159034 1 NC_008253.1 hypothetical protein 1159034 4190822 ECP_1102 Escherichia coli 536 hypothetical protein YP_669016.1 1158495 D 362663 CDS YP_669017.1 110641287 4190823 complement(1159096..1159728) 1 NC_008253.1 TetR family regulatory protein 1159728 4190823 ECP_1103 Escherichia coli 536 TetR family regulatory protein YP_669017.1 1159096 R 362663 CDS YP_669018.1 110641288 4190824 1159969..1160226 1 NC_008253.1 hypothetical protein 1160226 4190824 ECP_1104 Escherichia coli 536 hypothetical protein YP_669018.1 1159969 D 362663 CDS YP_669019.1 110641289 4190825 complement(1160309..1161268) 1 NC_008253.1 hypothetical protein 1161268 4190825 ECP_1105 Escherichia coli 536 hypothetical protein YP_669019.1 1160309 R 362663 CDS YP_669020.1 110641290 4190826 complement(1161416..1164910) 1 NC_008253.1 transcription-repair coupling factor 1164910 4190826 ECP_1106 Escherichia coli 536 transcription-repair coupling factor YP_669020.1 1161416 R 362663 CDS YP_669021.1 110641291 4190827 complement(1164990..1165337) 1 NC_008253.1 similart to the C-terminal part of the hypothetical protein YcfT; hypothetical protein 1165337 4190827 ECP_1107 Escherichia coli 536 hypothetical protein YP_669021.1 1164990 R 362663 CDS YP_669022.1 110641292 4190828 complement(1165359..1166063) 1 NC_008253.1 similar to the N-terminal part of the hypothetical protein YcfT; hypothetical protein 1166063 4190828 ECP_1108 Escherichia coli 536 hypothetical protein YP_669022.1 1165359 R 362663 CDS YP_669023.1 110641293 4190829 1166325..1167524 1 NC_008253.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1167524 4190829 ECP_1109 Escherichia coli 536 outer membrane-specific lipoprotein transporter subunit LolC YP_669023.1 1166325 D 362663 CDS YP_669024.1 110641294 4190830 1167574..1168218 1 NC_008253.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1168218 lolD 4190830 lolD Escherichia coli 536 lipoprotein transporter ATP-binding subunit YP_669024.1 1167574 D 362663 CDS YP_669025.1 110641295 4190833 1169492..1170403 1 NC_008253.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1170403 4190833 ECP_1113 Escherichia coli 536 N-acetyl-D-glucosamine kinase YP_669025.1 1169492 D 362663 CDS YP_669026.1 110641296 4190834 1170419..1171240 1 NC_008253.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1171240 4190834 ECP_1114 Escherichia coli 536 NAD-dependent deacetylase YP_669026.1 1170419 D 362663 CDS YP_669027.1 110641297 4190835 complement(1171377..1172162) 1 NC_008253.1 hypothetical protein 1172162 4190835 ECP_1115 Escherichia coli 536 hypothetical protein YP_669027.1 1171377 R 362663 CDS YP_669028.1 110641298 4190836 complement(1172159..1172620) 1 NC_008253.1 membrane protein YmfA 1172620 4190836 ECP_1116 Escherichia coli 536 membrane protein YmfA YP_669028.1 1172159 R 362663 CDS YP_669029.1 110641299 4187470 complement(1172678..1173724) 1 NC_008253.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1173724 potD 4187470 potD Escherichia coli 536 spermidine/putrescine ABC transporter substrate-binding protein YP_669029.1 1172678 R 362663 CDS YP_669030.1 110641300 4187471 complement(1173721..1174515) 1 NC_008253.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1174515 potC 4187471 potC Escherichia coli 536 spermidine/putrescine ABC transporter membrane protein YP_669030.1 1173721 R 362663 CDS YP_669031.1 110641301 4187472 complement(1174512..1175369) 1 NC_008253.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1175369 potB 4187472 potB Escherichia coli 536 spermidine/putrescine ABC transporter membrane protein YP_669031.1 1174512 R 362663 CDS YP_669032.1 110641302 4187473 complement(1175353..1176489) 1 NC_008253.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1176489 potA 4187473 potA Escherichia coli 536 putrescine/spermidine ABC transporter ATPase YP_669032.1 1175353 R 362663 CDS YP_669033.1 110641303 4187474 complement(1176468..1176683) 1 NC_008253.1 hypothetical protein 1176683 4187474 ECP_1121 Escherichia coli 536 hypothetical protein YP_669033.1 1176468 R 362663 CDS YP_669034.1 110641304 4187475 1176739..1177965 1 NC_008253.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1177965 4187475 ECP_1122 Escherichia coli 536 peptidase T YP_669034.1 1176739 D 362663 CDS YP_669035.1 110641305 4187476 complement(1178014..1179144) 1 NC_008253.1 hypothetical protein 1179144 4187476 ECP_1123 Escherichia coli 536 hypothetical protein YP_669035.1 1178014 R 362663 CDS YP_669036.1 110641306 4187477 complement(1179211..1180671) 1 NC_008253.1 sensor protein PhoQ 1180671 4187477 ECP_1124 Escherichia coli 536 sensor protein PhoQ YP_669036.1 1179211 R 362663 CDS YP_669037.1 110641307 4187478 complement(1180671..1181342) 1 NC_008253.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1181342 4187478 ECP_1125 Escherichia coli 536 DNA-binding transcriptional regulator PhoP YP_669037.1 1180671 R 362663 CDS YP_669038.1 110641308 4187479 complement(1181512..1182882) 1 NC_008253.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1182882 4187479 ECP_1126 Escherichia coli 536 adenylosuccinate lyase YP_669038.1 1181512 R 362663 CDS YP_669039.1 110641309 4187480 complement(1182886..1183533) 1 NC_008253.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1183533 4187480 ECP_1127 Escherichia coli 536 hypothetical protein YP_669039.1 1182886 R 362663 CDS YP_669040.1 110641310 4187481 complement(1183563..1184669) 1 NC_008253.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1184669 mnmA 4187481 mnmA Escherichia coli 536 tRNA-specific 2-thiouridylase MnmA YP_669040.1 1183563 R 362663 CDS YP_669041.1 110641311 4187482 complement(1184723..1185184) 1 NC_008253.1 nudix hydrolase YmfB 1185184 4187482 ECP_1129 Escherichia coli 536 nudix hydrolase YmfB YP_669041.1 1184723 R 362663 CDS YP_669042.1 110641312 4187483 complement(1185194..1185847) 1 NC_008253.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1185847 4187483 ECP_1130 Escherichia coli 536 23S rRNA pseudouridine synthase E YP_669042.1 1185194 R 362663 CDS YP_669043.1 110641313 4187484 1186019..1187269 1 NC_008253.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1187269 4187484 ECP_1131 Escherichia coli 536 isocitrate dehydrogenase YP_669043.1 1186019 D 362663 CDS YP_669044.1 110641314 4187485 complement(1187383..1187871) 1 NC_008253.1 hypothetical protein 1187871 4187485 ECP_1132 Escherichia coli 536 hypothetical protein YP_669044.1 1187383 R 362663 CDS YP_669045.1 110641315 4187486 complement(1188067..1188846) 1 NC_008253.1 transposase/IS protein 1188846 4187486 ECP_1133 Escherichia coli 536 transposase/IS protein YP_669045.1 1188067 R 362663 CDS YP_669046.1 110641316 4187487 complement(1188846..1189868) 1 NC_008253.1 transposase for insertion sequence IS100 1189868 4187487 ECP_1134 Escherichia coli 536 transposase for insertion sequence IS100 YP_669046.1 1188846 R 362663 CDS YP_669047.1 110641317 4187488 complement(1189882..1190484) 1 NC_008253.1 hypothetical protein 1190484 4187488 ECP_1135 Escherichia coli 536 hypothetical protein YP_669047.1 1189882 R 362663 CDS YP_669048.1 110641318 4188022 complement(1190474..1190710) 1 NC_008253.1 excisionase 1190710 4188022 ECP_1136 Escherichia coli 536 excisionase YP_669048.1 1190474 R 362663 CDS YP_669049.1 110641319 4188023 complement(1190850..1191089) 1 NC_008253.1 hypothetical protein 1191089 4188023 ECP_1137 Escherichia coli 536 hypothetical protein YP_669049.1 1190850 R 362663 CDS YP_669050.1 110641320 4188024 complement(1191137..1191355) 1 NC_008253.1 hypothetical protein 1191355 4188024 ECP_1138 Escherichia coli 536 hypothetical protein YP_669050.1 1191137 R 362663 CDS YP_669051.1 110641321 4188025 complement(1191454..1191669) 1 NC_008253.1 hypothetical protein 1191669 4188025 ECP_1139 Escherichia coli 536 hypothetical protein YP_669051.1 1191454 R 362663 CDS YP_669052.1 110641322 4188026 complement(1192089..1192769) 1 NC_008253.1 exonuclease 1192769 4188026 ECP_1140 Escherichia coli 536 exonuclease YP_669052.1 1192089 R 362663 CDS YP_669053.1 110641323 4188027 complement(1192766..1193551) 1 NC_008253.1 bacteriophage recombination protein 1193551 4188027 ECP_1141 Escherichia coli 536 bacteriophage recombination protein YP_669053.1 1192766 R 362663 CDS YP_669054.1 110641324 4188028 complement(1193557..1193853) 1 NC_008253.1 host-nuclease inhibitor protein Gam 1193853 4188028 ECP_1142 Escherichia coli 536 host-nuclease inhibitor protein Gam YP_669054.1 1193557 R 362663 CDS YP_669055.1 110641325 4188029 complement(1193928..1194314) 1 NC_008253.1 prophage Kil protein 1194314 4188029 ECP_1143 Escherichia coli 536 prophage Kil protein YP_669055.1 1193928 R 362663 CDS YP_669056.1 110641326 4188030 complement(1194610..1194987) 1 NC_008253.1 phage associated protein 1194987 4188030 ECP_1144 Escherichia coli 536 phage associated protein YP_669056.1 1194610 R 362663 CDS YP_669057.1 110641327 4188031 complement(1194965..1196026) 1 NC_008253.1 hypothetical protein 1196026 4188031 ECP_1145 Escherichia coli 536 hypothetical protein YP_669057.1 1194965 R 362663 CDS YP_669058.1 110641328 4188032 complement(1196107..1196799) 1 NC_008253.1 regulatory protein CI; phage-related repressor protein 1196799 4188032 ECP_1146 Escherichia coli 536 phage-related repressor protein YP_669058.1 1196107 R 362663 CDS YP_669059.1 110641329 4188033 1196910..1197137 1 NC_008253.1 hypothetical protein 1197137 4188033 ECP_1147 Escherichia coli 536 hypothetical protein YP_669059.1 1196910 D 362663 CDS YP_669060.1 110641330 4188034 1197162..1197707 1 NC_008253.1 bacteriophage regulatory protein CII 1197707 4188034 ECP_1148 Escherichia coli 536 bacteriophage regulatory protein CII YP_669060.1 1197162 D 362663 CDS YP_669061.1 110641331 4188035 1197704..1198723 1 NC_008253.1 replication protein O 1198723 4188035 ECP_1149 Escherichia coli 536 replication protein O YP_669061.1 1197704 D 362663 CDS YP_669062.1 110641332 4188036 1198720..1199433 1 NC_008253.1 replication protein 14 1199433 4188036 ECP_1150 Escherichia coli 536 replication protein 14 YP_669062.1 1198720 D 362663 CDS YP_669063.1 110641333 4188037 complement(1199512..1199940) 1 NC_008253.1 hypothetical protein 1199940 4188037 ECP_1151 Escherichia coli 536 hypothetical protein YP_669063.1 1199512 R 362663 CDS YP_669064.1 110641334 4188038 complement(1199937..1200314) 1 NC_008253.1 hypothetical protein 1200314 4188038 ECP_1152 Escherichia coli 536 hypothetical protein YP_669064.1 1199937 R 362663 CDS YP_669065.1 110641335 4188039 1200582..1201037 1 NC_008253.1 DLP12 prophage; hypothetical protein 1201037 4188039 ECP_1153 Escherichia coli 536 hypothetical protein YP_669065.1 1200582 D 362663 CDS YP_669066.1 110641336 4188040 1201200..1201490 1 NC_008253.1 hypothetical protein 1201490 4188040 ECP_1154 Escherichia coli 536 hypothetical protein YP_669066.1 1201200 D 362663 CDS YP_669067.1 110641337 4188041 1201487..1201849 1 NC_008253.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1201849 4188041 ECP_1155 Escherichia coli 536 endodeoxyribonuclease RUS YP_669067.1 1201487 D 362663 CDS YP_669068.1 110641338 4191800 1202072..1202455 1 NC_008253.1 antitermination protein Q 1202455 4191800 ECP_1156 Escherichia coli 536 antitermination protein Q YP_669068.1 1202072 D 362663 CDS YP_669069.1 110641339 4191801 complement(1202644..1203726) 1 NC_008253.1 outer membrane porin protein LC 1203726 4191801 ECP_1157 Escherichia coli 536 outer membrane porin protein LC YP_669069.1 1202644 R 362663 CDS YP_669070.1 110641340 4191802 1204055..1204204 1 NC_008253.1 hypothetical protein 1204204 4191802 ECP_1158 Escherichia coli 536 hypothetical protein YP_669070.1 1204055 D 362663 CDS YP_669071.1 110641341 4191803 1204315..1204530 1 NC_008253.1 lysis protein S 1204530 4191803 ECP_1159 Escherichia coli 536 lysis protein S YP_669071.1 1204315 D 362663 CDS YP_669072.1 110641342 4191804 1204530..1205027 1 NC_008253.1 lysozyme 1205027 4191804 ECP_1160 Escherichia coli 536 lysozyme YP_669072.1 1204530 D 362663 CDS YP_669073.1 110641343 4191805 1205024..1205485 1 NC_008253.1 endopeptidase 1205485 4191805 ECP_1161 Escherichia coli 536 endopeptidase YP_669073.1 1205024 D 362663 CDS YP_669074.1 110641344 4191806 complement(1205517..1205810) 1 NC_008253.1 Bor protein 1205810 4191806 ECP_1162 Escherichia coli 536 Bor protein YP_669074.1 1205517 R 362663 CDS YP_669075.1 110641345 4191807 1206291..1206617 1 NC_008253.1 may be prophage encoded; TonB-like membrane protein 1206617 4191807 ECP_1163 Escherichia coli 536 TonB-like membrane protein YP_669075.1 1206291 D 362663 CDS YP_669076.1 110641346 4191808 1206824..1207006 1 NC_008253.1 hypothetical protein 1207006 4191808 ECP_1164 Escherichia coli 536 hypothetical protein YP_669076.1 1206824 D 362663 CDS YP_669077.1 110641347 4191809 1207236..1207487 1 NC_008253.1 hypothetical protein 1207487 4191809 ECP_1165 Escherichia coli 536 hypothetical protein YP_669077.1 1207236 D 362663 CDS YP_669078.1 110641348 4191810 1207569..1208114 1 NC_008253.1 terminase small subunit 1208114 4191810 ECP_1166 Escherichia coli 536 terminase small subunit YP_669078.1 1207569 D 362663 CDS YP_669079.1 110641349 4191811 1208089..1210014 1 NC_008253.1 terminase large subunit 1210014 4191811 ECP_1167 Escherichia coli 536 terminase large subunit YP_669079.1 1208089 D 362663 CDS YP_669080.1 110641350 4191812 1210011..1210217 1 NC_008253.1 head-to-tail joining protein W 1210217 4191812 ECP_1168 Escherichia coli 536 head-to-tail joining protein W YP_669080.1 1210011 D 362663 CDS YP_669081.1 110641351 4191813 1210214..1211815 1 NC_008253.1 minor capsid protein B 1211815 4191813 ECP_1169 Escherichia coli 536 minor capsid protein B YP_669081.1 1210214 D 362663 CDS YP_669082.1 110641352 4191814 1211796..1213115 1 NC_008253.1 minor capsid protein C 1213115 4191814 ECP_1170 Escherichia coli 536 minor capsid protein C YP_669082.1 1211796 D 362663 CDS YP_669083.1 110641353 4191815 1213125..1213457 1 NC_008253.1 major capsid protein D 1213457 4191815 ECP_1171 Escherichia coli 536 major capsid protein D YP_669083.1 1213125 D 362663 CDS YP_669084.1 110641354 4191816 1213513..1214538 1 NC_008253.1 major coat protein 1214538 4191816 ECP_1172 Escherichia coli 536 major coat protein YP_669084.1 1213513 D 362663 CDS YP_669085.1 110641355 4191817 1214580..1214975 1 NC_008253.1 DNA packaging protein FI 1214975 4191817 ECP_1173 Escherichia coli 536 DNA packaging protein FI YP_669085.1 1214580 D 362663 CDS YP_669086.1 110641356 4191818 1214987..1215340 1 NC_008253.1 tail attachment protein minor capsid protein FII) 1215340 4191818 ECP_1174 Escherichia coli 536 tail attachment protein minor capsid protein FII) YP_669086.1 1214987 D 362663 CDS YP_669087.1 110641357 4189104 1215352..1215930 1 NC_008253.1 minor tail protein Z 1215930 4189104 ECP_1175 Escherichia coli 536 minor tail protein Z YP_669087.1 1215352 D 362663 CDS YP_669088.1 110641358 4189105 1215927..1216322 1 NC_008253.1 minor tail protein U 1216322 4189105 ECP_1176 Escherichia coli 536 minor tail protein U YP_669088.1 1215927 D 362663 CDS YP_669089.1 110641359 4189106 1216330..1217070 1 NC_008253.1 major tail protein V 1217070 4189106 ECP_1177 Escherichia coli 536 major tail protein V YP_669089.1 1216330 D 362663 CDS YP_669090.1 110641360 4189107 1217086..1217508 1 NC_008253.1 minor tail protein G 1217508 4189107 ECP_1178 Escherichia coli 536 minor tail protein G YP_669090.1 1217086 D 362663 CDS YP_669091.1 110641361 4189108 1217490..1217924 1 NC_008253.1 minor tail protein T 1217924 4189108 ECP_1179 Escherichia coli 536 minor tail protein T YP_669091.1 1217490 D 362663 CDS YP_669092.1 110641362 4189109 1217917..1220484 1 NC_008253.1 minor tail protein H 1220484 4189109 ECP_1180 Escherichia coli 536 minor tail protein H YP_669092.1 1217917 D 362663 CDS YP_669093.1 110641363 4189110 1220481..1220810 1 NC_008253.1 minor tail protein M 1220810 4189110 ECP_1181 Escherichia coli 536 minor tail protein M YP_669093.1 1220481 D 362663 CDS YP_669094.1 110641364 4189111 1220810..1221508 1 NC_008253.1 minor tail protein L 1221508 4189111 ECP_1182 Escherichia coli 536 minor tail protein L YP_669094.1 1220810 D 362663 CDS YP_669095.1 110641365 4189112 1221514..1222257 1 NC_008253.1 tail assembly protein K 1222257 4189112 ECP_1183 Escherichia coli 536 tail assembly protein K YP_669095.1 1221514 D 362663 CDS YP_669096.1 110641366 4189113 1222155..1222826 1 NC_008253.1 tail assembly protein I 1222826 4189113 ECP_1184 Escherichia coli 536 tail assembly protein I YP_669096.1 1222155 D 362663 CDS YP_669097.1 110641367 4189114 1222887..1226369 1 NC_008253.1 host specificity protein J 1226369 4189114 ECP_1185 Escherichia coli 536 host specificity protein J YP_669097.1 1222887 D 362663 CDS YP_669098.1 110641368 4189115 1226428..1228488 1 NC_008253.1 tail fiber protein 1228488 4189115 ECP_1186 Escherichia coli 536 tail fiber protein YP_669098.1 1226428 D 362663 CDS YP_669099.1 110641369 4189116 1228485..1228763 1 NC_008253.1 hypothetical protein 1228763 4189116 ECP_1187 Escherichia coli 536 hypothetical protein YP_669099.1 1228485 D 362663 CDS YP_669100.1 110641370 4189117 1228776..1229069 1 NC_008253.1 hypothetical protein 1229069 4189117 ECP_1188 Escherichia coli 536 hypothetical protein YP_669100.1 1228776 D 362663 CDS YP_669101.1 110641371 4189118 complement(1229161..1230018) 1 NC_008253.1 iron transport protein, inner membrane component 1230018 4189118 ECP_1189 Escherichia coli 536 iron transport protein, inner membrane component YP_669101.1 1229161 R 362663 CDS YP_669102.1 110641372 4189119 complement(1230015..1230872) 1 NC_008253.1 iron transport protein, inner membrane component 1230872 4189119 ECP_1190 Escherichia coli 536 iron transport protein, inner membrane component YP_669102.1 1230015 R 362663 CDS YP_669103.1 110641373 4189120 complement(1230869..1231696) 1 NC_008253.1 iron ABC transporter ATP-binding protein 1231696 4189120 ECP_1191 Escherichia coli 536 iron ABC transporter ATP-binding protein YP_669103.1 1230869 R 362663 CDS YP_669104.1 110641374 4189121 complement(1231696..1232610) 1 NC_008253.1 iron transport protein, periplasmic-binding protein 1232610 4189121 ECP_1192 Escherichia coli 536 iron transport protein, periplasmic-binding protein YP_669104.1 1231696 R 362663 CDS YP_669105.1 110641375 4189122 1232889..1233482 1 NC_008253.1 acetyltransferase 1233482 4189122 ECP_1193 Escherichia coli 536 acetyltransferase YP_669105.1 1232889 D 362663 CDS YP_669106.1 110641376 4189123 1233737..1234321 1 NC_008253.1 transcriptional regulator 1234321 4189123 ECP_1194 Escherichia coli 536 transcriptional regulator YP_669106.1 1233737 D 362663 CDS YP_669107.1 110641377 4189012 complement(1234346..1234783) 1 NC_008253.1 hypothetical protein 1234783 4189012 ECP_1195 Escherichia coli 536 hypothetical protein YP_669107.1 1234346 R 362663 CDS YP_669108.1 110641378 4189013 complement(1235057..1235224) 1 NC_008253.1 hypothetical protein 1235224 4189013 ECP_1196 Escherichia coli 536 hypothetical protein YP_669108.1 1235057 R 362663 CDS YP_669109.1 110641379 4189014 1235263..1235415 1 NC_008253.1 hypothetical protein 1235415 4189014 ECP_1197 Escherichia coli 536 hypothetical protein YP_669109.1 1235263 D 362663 CDS YP_669110.1 110641380 4189015 complement(1235677..1236081) 1 NC_008253.1 hypothetical protein 1236081 4189015 ECP_1198 Escherichia coli 536 hypothetical protein YP_669110.1 1235677 R 362663 CDS YP_669111.1 110641381 4189016 complement(1236302..1237033) 1 NC_008253.1 transcriptional regulator YcgE 1237033 4189016 ECP_1199 Escherichia coli 536 transcriptional regulator YcgE YP_669111.1 1236302 R 362663 CDS YP_669112.1 110641382 4189017 complement(1237238..1238449) 1 NC_008253.1 hypothetical protein 1238449 4189017 ECP_1200 Escherichia coli 536 hypothetical protein YP_669112.1 1237238 R 362663 CDS YP_669113.1 110641383 4189018 1238763..1238999 1 NC_008253.1 hypothetical protein 1238999 4189018 ECP_1201 Escherichia coli 536 hypothetical protein YP_669113.1 1238763 D 362663 CDS YP_669114.1 110641384 4189019 1239042..1239314 1 NC_008253.1 hypothetical protein 1239314 4189019 ECP_1202 Escherichia coli 536 hypothetical protein YP_669114.1 1239042 D 362663 CDS YP_669115.1 110641385 4189020 1239343..1239609 1 NC_008253.1 hypothetical protein 1239609 4189020 ECP_1203 Escherichia coli 536 hypothetical protein YP_669115.1 1239343 D 362663 CDS YP_669116.1 110641386 4189021 1239722..1239970 1 NC_008253.1 hypothetical protein 1239970 4189021 ECP_1204 Escherichia coli 536 hypothetical protein YP_669116.1 1239722 D 362663 CDS YP_669117.1 110641387 4189022 1240310..1241161 1 NC_008253.1 hypothetical protein 1241161 4189022 ECP_1205 Escherichia coli 536 hypothetical protein YP_669117.1 1240310 D 362663 CDS YP_669118.1 110641388 4189023 1241257..1241511 1 NC_008253.1 hypothetical protein 1241511 4189023 ECP_1206 Escherichia coli 536 hypothetical protein YP_669118.1 1241257 D 362663 CDS YP_669119.1 110641389 4189024 1241909..1242088 1 NC_008253.1 hypothetical protein 1242088 4189024 ECP_1207 Escherichia coli 536 hypothetical protein YP_669119.1 1241909 D 362663 CDS YP_669120.1 110641390 4189025 1242378..1242755 1 NC_008253.1 hypothetical protein 1242755 4189025 ECP_1208 Escherichia coli 536 hypothetical protein YP_669120.1 1242378 D 362663 CDS YP_669121.1 110641391 4189026 1242901..1243428 1 NC_008253.1 hypothetical protein 1243428 4189026 ECP_1209 Escherichia coli 536 hypothetical protein YP_669121.1 1242901 D 362663 CDS YP_669122.1 110641392 4189027 complement(1243486..1243815) 1 NC_008253.1 hypothetical protein 1243815 4189027 ECP_1210 Escherichia coli 536 hypothetical protein YP_669122.1 1243486 R 362663 CDS YP_669123.1 110641393 4189028 complement(1243825..1244109) 1 NC_008253.1 hypothetical protein 1244109 4189028 ECP_1211 Escherichia coli 536 hypothetical protein YP_669123.1 1243825 R 362663 CDS YP_669124.1 110641394 4189029 complement(1244171..1244344) 1 NC_008253.1 hypothetical protein 1244344 4189029 ECP_1212 Escherichia coli 536 hypothetical protein YP_669124.1 1244171 R 362663 CDS YP_669125.1 110641395 4189030 1244445..1244630 1 NC_008253.1 hypothetical protein 1244630 4189030 ECP_1213 Escherichia coli 536 hypothetical protein YP_669125.1 1244445 D 362663 CDS YP_669126.1 110641396 4189850 1244762..1245088 1 NC_008253.1 autotransporter 1245088 4189850 ECP_1214 Escherichia coli 536 autotransporter YP_669126.1 1244762 D 362663 CDS YP_669127.1 110641397 4189851 1245134..1245319 1 NC_008253.1 hypothetical protein 1245319 4189851 ECP_1215 Escherichia coli 536 hypothetical protein YP_669127.1 1245134 D 362663 CDS YP_669128.1 110641398 4189852 complement(1245461..1245727) 1 NC_008253.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1245727 minE 4189852 minE Escherichia coli 536 cell division topological specificity factor MinE YP_669128.1 1245461 R 362663 CDS YP_669129.1 110641399 4189853 complement(1245731..1246543) 1 NC_008253.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1246543 4189853 ECP_1217 Escherichia coli 536 cell division inhibitor MinD YP_669129.1 1245731 R 362663 CDS YP_669130.1 110641400 4189854 complement(1246567..1247262) 1 NC_008253.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1247262 minC 4189854 minC Escherichia coli 536 septum formation inhibitor YP_669130.1 1246567 R 362663 CDS YP_669131.1 110641401 4189855 1247402..1247629 1 NC_008253.1 hypothetical protein 1247629 4189855 ECP_1219 Escherichia coli 536 hypothetical protein YP_669131.1 1247402 D 362663 CDS YP_669132.1 110641402 4189856 1247782..1248150 1 NC_008253.1 hypothetical protein 1248150 4189856 ECP_1220 Escherichia coli 536 hypothetical protein YP_669132.1 1247782 D 362663 CDS YP_669133.1 110641403 4189857 complement(1248253..1248654) 1 NC_008253.1 protein YcgK 1248654 4189857 ECP_1221 Escherichia coli 536 protein YcgK YP_669133.1 1248253 R 362663 CDS YP_669134.1 110641404 4189858 1248863..1249189 1 NC_008253.1 hypothetical protein 1249189 4189858 ECP_1222 Escherichia coli 536 hypothetical protein YP_669134.1 1248863 D 362663 CDS YP_669135.1 110641405 4189859 1249261..1249920 1 NC_008253.1 hypothetical protein 1249920 4189859 ECP_1223 Escherichia coli 536 hypothetical protein YP_669135.1 1249261 D 362663 CDS YP_669136.2 162138278 4189860 1250012..1250458 1 NC_008253.1 hypothetical protein 1250458 4189860 ECP_1224 Escherichia coli 536 hypothetical protein YP_669136.2 1250012 D 362663 CDS YP_669137.1 110641407 4189861 complement(1250665..1250946) 1 NC_008253.1 hypothetical protein 1250946 4189861 ECP_1225 Escherichia coli 536 hypothetical protein YP_669137.1 1250665 R 362663 CDS YP_669138.1 110641408 4189862 1251238..1251657 1 NC_008253.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1251657 4189862 ECP_1226 Escherichia coli 536 DNA polymerase V subunit UmuD YP_669138.1 1251238 D 362663 CDS YP_669139.1 110641409 4189863 1251657..1252925 1 NC_008253.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1252925 umuC 4189863 umuC Escherichia coli 536 DNA polymerase V subunit UmuC YP_669139.1 1251657 D 362663 CDS YP_669140.1 110641410 4189864 complement(1252970..1253500) 1 NC_008253.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1253500 4189864 ECP_1228 Escherichia coli 536 disulfide bond formation protein B YP_669140.1 1252970 R 362663 CDS YP_669141.1 110641411 4189865 complement(1253646..1255187) 1 NC_008253.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1255187 nhaB 4189865 nhaB Escherichia coli 536 sodium/proton antiporter YP_669141.1 1253646 R 362663 CDS YP_669142.1 110641412 4189866 1255409..1256128 1 NC_008253.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1256128 4189866 ECP_1230 Escherichia coli 536 fatty acid metabolism regulator YP_669142.1 1255409 D 362663 CDS YP_669143.1 110641413 4189867 complement(1256291..1257823) 1 NC_008253.1 SpoVR family protein 1257823 4189867 ECP_1231 Escherichia coli 536 SpoVR family protein YP_669143.1 1256291 R 362663 CDS YP_669144.1 110641414 4189868 1258153..1259451 1 NC_008253.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1259451 4189868 ECP_1232 Escherichia coli 536 D-amino acid dehydrogenase small subunit YP_669144.1 1258153 D 362663 CDS YP_669145.1 110641415 4189869 1259461..1260531 1 NC_008253.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1260531 dadX 4189869 dadX Escherichia coli 536 alanine racemase YP_669145.1 1259461 D 362663 CDS YP_669146.1 110641416 4191976 complement(1260588..1262324) 1 NC_008253.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1262324 4191976 ECP_1234 Escherichia coli 536 potassium/proton antiporter YP_669146.1 1260588 R 362663 CDS YP_669147.1 110641417 4191977 complement(1262419..1263333) 1 NC_008253.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1263333 ldcA 4191977 ldcA Escherichia coli 536 L,D-carboxypeptidase A YP_669147.1 1262419 R 362663 CDS YP_669148.1 110641418 4191978 1263319..1264044 1 NC_008253.1 membrane-bound lytic murein transglycosylase E 1264044 4191978 ECP_1236 Escherichia coli 536 membrane-bound lytic murein transglycosylase E YP_669148.1 1263319 D 362663 CDS YP_669149.1 110641419 4191979 complement(1264046..1264780) 1 NC_008253.1 hypothetical protein 1264780 4191979 ECP_1237 Escherichia coli 536 hypothetical protein YP_669149.1 1264046 R 362663 CDS YP_669150.1 110641420 4191980 1264981..1265235 1 NC_008253.1 transglycosylase associated protein 1265235 4191980 ECP_1238 Escherichia coli 536 transglycosylase associated protein YP_669150.1 1264981 D 362663 CDS YP_669151.1 110641421 4191981 complement(1265285..1267255) 1 NC_008253.1 TonB-dependent outer membrane receptor 1267255 4191981 ECP_1239 Escherichia coli 536 TonB-dependent outer membrane receptor YP_669151.1 1265285 R 362663 CDS YP_669152.1 110641422 4191982 complement(1267281..1268135) 1 NC_008253.1 involved in molybdenum transport; molybdenum transport protein ModD 1268135 4191982 ECP_1240 Escherichia coli 536 molybdenum transport protein ModD YP_669152.1 1267281 R 362663 CDS YP_669153.1 110641423 4191983 complement(1268132..1268944) 1 NC_008253.1 hypothetical protein 1268944 4191983 ECP_1241 Escherichia coli 536 hypothetical protein YP_669153.1 1268132 R 362663 CDS YP_669154.1 110641424 4191984 complement(1268954..1269712) 1 NC_008253.1 iron ABC transporter ATP-binding protein 1269712 4191984 ECP_1242 Escherichia coli 536 iron ABC transporter ATP-binding protein YP_669154.1 1268954 R 362663 CDS YP_669155.1 110641425 4191985 complement(1269709..1270689) 1 NC_008253.1 iron(III) ABC transporter permease 1270689 4191985 ECP_1243 Escherichia coli 536 iron(III) ABC transporter permease YP_669155.1 1269709 R 362663 CDS YP_669156.1 110641426 4191986 complement(1270689..1271711) 1 NC_008253.1 iron ABC transporter substrate-binding protein 1271711 4191986 ECP_1244 Escherichia coli 536 iron ABC transporter substrate-binding protein YP_669156.1 1270689 R 362663 CDS YP_669157.1 110641427 4191987 complement(1272048..1273745) 1 NC_008253.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1273745 treA 4191987 treA Escherichia coli 536 trehalase YP_669157.1 1272048 R 362663 CDS YP_669158.1 110641428 4191988 complement(1274065..1275483) 1 NC_008253.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone; dihydroxyacetone kinase subunit DhaM 1275483 4191988 ECP_1246 Escherichia coli 536 dihydroxyacetone kinase subunit DhaM YP_669158.1 1274065 R 362663 CDS YP_669159.1 110641429 4191989 complement(1275494..1276126) 1 NC_008253.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase ADP-binding subunit 1276126 4191989 ECP_1247 Escherichia coli 536 dihydroxyacetone kinase ADP-binding subunit YP_669159.1 1275494 R 362663 CDS YP_669160.1 110641430 4191990 complement(1276137..1277207) 1 NC_008253.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1277207 4191990 ECP_1248 Escherichia coli 536 dihydroxyacetone kinase subunit DhaK YP_669160.1 1276137 R 362663 CDS YP_669161.1 110641431 4191991 1277435..1279354 1 NC_008253.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1279354 4191991 ECP_1249 Escherichia coli 536 DNA-binding transcriptional regulator DhaR YP_669161.1 1277435 D 362663 CDS YP_669162.1 110641432 4191992 complement(1279391..1279621) 1 NC_008253.1 hypothetical protein 1279621 4191992 ECP_1250 Escherichia coli 536 hypothetical protein YP_669162.1 1279391 R 362663 CDS YP_669163.1 110641433 4191993 complement(1279759..1280850) 1 NC_008253.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1280850 4191993 ECP_1251 Escherichia coli 536 GTP-dependent nucleic acid-binding protein EngD YP_669163.1 1279759 R 362663 CDS YP_669164.1 110641434 4191994 complement(1280967..1281551) 1 NC_008253.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1281551 4191994 ECP_1252 Escherichia coli 536 peptidyl-tRNA hydrolase YP_669164.1 1280967 R 362663 CDS YP_669165.1 110641435 4189735 1281829..1282107 1 NC_008253.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1282107 4189735 ECP_1253 Escherichia coli 536 hypothetical protein YP_669165.1 1281829 D 362663 CDS YP_669166.1 110641436 4189736 complement(1282162..1283814) 1 NC_008253.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1283814 4189736 ECP_1254 Escherichia coli 536 sulfate transporter YchM YP_669166.1 1282162 R 362663 CDS YP_669167.1 110641437 4189737 complement(1283966..1284913) 1 NC_008253.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1284913 4189737 ECP_1255 Escherichia coli 536 ribose-phosphate pyrophosphokinase YP_669167.1 1283966 R 362663 CDS YP_669168.1 110641438 4189738 complement(1285064..1285915) 1 NC_008253.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1285915 ipk 4189738 ipk Escherichia coli 536 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_669168.1 1285064 R 362663 CDS YP_669169.1 110641439 4189739 complement(1285915..1286538) 1 NC_008253.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 1286538 lolB 4189739 lolB Escherichia coli 536 molecular chaperone LolB YP_669169.1 1285915 R 362663 CDS YP_669170.1 110641440 4189740 1286752..1288008 1 NC_008253.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1288008 hemA 4189740 hemA Escherichia coli 536 glutamyl-tRNA reductase YP_669170.1 1286752 D 362663 CDS YP_669171.1 110641441 4189741 1288050..1289132 1 NC_008253.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1289132 prfA 4189741 prfA Escherichia coli 536 peptide chain release factor 1 YP_669171.1 1288050 D 362663 CDS YP_669172.1 110641442 4189742 1289132..1289965 1 NC_008253.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1289965 4189742 ECP_1260 Escherichia coli 536 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_669172.1 1289132 D 362663 CDS YP_669173.1 110641443 4189743 1289962..1290354 1 NC_008253.1 transcriptional regulator 1290354 4189743 ECP_1261 Escherichia coli 536 transcriptional regulator YP_669173.1 1289962 D 362663 CDS YP_669174.1 110641444 4189744 1290358..1291167 1 NC_008253.1 transcriptional regulator 1291167 4189744 ECP_1262 Escherichia coli 536 transcriptional regulator YP_669174.1 1290358 D 362663 CDS YP_669175.1 110641445 4189745 1291203..1292057 1 NC_008253.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1292057 4189745 ECP_1263 Escherichia coli 536 2-dehydro-3-deoxyphosphooctonate aldolase YP_669175.1 1291203 D 362663 CDS YP_669176.1 110641446 4189746 complement(1292205..1292372) 1 NC_008253.1 hypothetical protein 1292372 4189746 ECP_1264 Escherichia coli 536 hypothetical protein YP_669176.1 1292205 R 362663 CDS YP_669177.1 110641447 4189747 complement(1292717..1293817) 1 NC_008253.1 calcium/sodium:proton antiporter 1293817 4189747 ECP_1265 Escherichia coli 536 calcium/sodium:proton antiporter YP_669177.1 1292717 R 362663 CDS YP_669178.1 110641448 4189748 1294087..1294317 1 NC_008253.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1294317 chaB 4189748 chaB Escherichia coli 536 cation transport regulator YP_669178.1 1294087 D 362663 CDS YP_669179.1 110641449 4189749 1294454..1295170 1 NC_008253.1 cation transport protein ChaC 1295170 4189749 ECP_1267 Escherichia coli 536 cation transport protein ChaC YP_669179.1 1294454 D 362663 CDS YP_669180.1 110641450 4189750 complement(1295214..1295567) 1 NC_008253.1 hypothetical protein 1295567 4189750 ECP_1268 Escherichia coli 536 hypothetical protein YP_669180.1 1295214 R 362663 CDS YP_669181.1 110641451 4189751 1295752..1297146 1 NC_008253.1 hypothetical protein 1297146 4189751 ECP_1269 Escherichia coli 536 hypothetical protein YP_669181.1 1295752 D 362663 CDS YP_669182.1 110641452 4189752 complement(1297147..1297797) 1 NC_008253.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1297797 4189752 ECP_1270 Escherichia coli 536 transcriptional regulator NarL YP_669182.1 1297147 R 362663 CDS YP_669183.1 110641453 4189753 complement(1297790..1299586) 1 NC_008253.1 nitrate/nitrite sensor protein NarX 1299586 4189753 ECP_1271 Escherichia coli 536 nitrate/nitrite sensor protein NarX YP_669183.1 1297790 R 362663 CDS YP_669184.1 110641454 4189754 1299612..1299830 1 NC_008253.1 hypothetical protein 1299830 4189754 ECP_1272 Escherichia coli 536 hypothetical protein YP_669184.1 1299612 D 362663 CDS YP_669185.1 110641455 4189755 1299925..1301316 1 NC_008253.1 nitrite extrusion protein 1301316 4189755 ECP_1273 Escherichia coli 536 nitrite extrusion protein YP_669185.1 1299925 D 362663 CDS YP_669186.1 110641456 4189756 1301709..1305452 1 NC_008253.1 respiratory nitrate reductase 1 subunit alpha 1305452 4189756 ECP_1274 Escherichia coli 536 respiratory nitrate reductase 1 subunit alpha YP_669186.1 1301709 D 362663 CDS YP_669187.1 110641457 4189757 1305449..1306987 1 NC_008253.1 respiratory nitrate reductase 1 subunit beta 1306987 4189757 ECP_1275 Escherichia coli 536 respiratory nitrate reductase 1 subunit beta YP_669187.1 1305449 D 362663 CDS YP_669188.1 110641458 4189758 1306984..1307694 1 NC_008253.1 respiratory nitrate reductase 1 subunit delta 1307694 4189758 ECP_1276 Escherichia coli 536 respiratory nitrate reductase 1 subunit delta YP_669188.1 1306984 D 362663 CDS YP_669189.1 110641459 4189759 1307694..1308371 1 NC_008253.1 respiratory nitrate reductase 1 subunit gamma 1308371 4189759 ECP_1277 Escherichia coli 536 respiratory nitrate reductase 1 subunit gamma YP_669189.1 1307694 D 362663 CDS YP_669190.1 110641460 4189760 complement(1308424..1309623) 1 NC_008253.1 transposase 1309623 4189760 ECP_1278 Escherichia coli 536 transposase YP_669190.1 1308424 R 362663 CDS YP_669191.1 110641461 4189761 complement(1310417..1311259) 1 NC_008253.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1311259 purU 4189761 purU Escherichia coli 536 formyltetrahydrofolate deformylase YP_669191.1 1310417 R 362663 CDS YP_669192.1 110641462 4189762 complement(1311309..1311767) 1 NC_008253.1 hypothetical protein 1311767 4189762 ECP_1280 Escherichia coli 536 hypothetical protein YP_669192.1 1311309 R 362663 CDS YP_669193.1 110641463 4189763 1311880..1312785 1 NC_008253.1 hypothetical protein 1312785 4189763 ECP_1281 Escherichia coli 536 hypothetical protein YP_669193.1 1311880 D 362663 CDS YP_669194.1 110641464 4189764 1312877..1313890 1 NC_008253.1 response regulator of RpoS 1313890 4189764 ECP_1282 Escherichia coli 536 response regulator of RpoS YP_669194.1 1312877 D 362663 CDS YP_669195.1 110641465 4189765 1314092..1315000 1 NC_008253.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1315000 4189765 ECP_1283 Escherichia coli 536 UTP-glucose-1-phosphate uridylyltransferase YP_669195.1 1314092 D 362663 CDS YP_669196.1 110641466 4189766 complement(1315144..1315557) 1 NC_008253.1 global DNA-binding transcriptional dual regulator H-NS 1315557 4189766 ECP_1284 Escherichia coli 536 global DNA-binding transcriptional dual regulator H-NS YP_669196.1 1315144 R 362663 CDS YP_669197.1 110641467 4189767 1316161..1316778 1 NC_008253.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1316778 4189767 ECP_1285 Escherichia coli 536 thymidine kinase YP_669197.1 1316161 D 362663 CDS YP_669198.1 110641468 4189768 complement(1316905..1318110) 1 NC_008253.1 for insertion sequence element IS4; transposase InsG 1318110 4189768 ECP_1286 Escherichia coli 536 transposase InsG YP_669198.1 1316905 R 362663 CDS YP_669199.1 110641469 4189769 complement(1318236..1320911) 1 NC_008253.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1320911 4189769 ECP_1287 Escherichia coli 536 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_669199.1 1318236 R 362663 CDS YP_669200.1 110641470 4189770 1321388..1322035 1 NC_008253.1 hypothetical protein 1322035 4189770 ECP_1288 Escherichia coli 536 hypothetical protein YP_669200.1 1321388 D 362663 CDS YP_669201.1 110641471 4189771 complement(1322193..1322489) 1 NC_008253.1 hypothetical protein 1322489 4189771 ECP_1289 Escherichia coli 536 hypothetical protein YP_669201.1 1322193 R 362663 CDS YP_669202.1 110641472 4189772 1322728..1324404 1 NC_008253.1 periplasmic oligopeptide-binding protein 1324404 4189772 ECP_1290 Escherichia coli 536 periplasmic oligopeptide-binding protein YP_669202.1 1322728 D 362663 CDS YP_669203.1 110641473 4189773 1324490..1325410 1 NC_008253.1 oligopeptide transporter permease 1325410 oppB 4189773 oppB Escherichia coli 536 oligopeptide transporter permease YP_669203.1 1324490 D 362663 CDS YP_669204.1 110641474 4190235 1325425..1326333 1 NC_008253.1 oligopeptide transport system permease OppC 1326333 4190235 ECP_1292 Escherichia coli 536 oligopeptide transport system permease OppC YP_669204.1 1325425 D 362663 CDS YP_669205.1 110641475 4190236 1326345..1327358 1 NC_008253.1 oligopeptide ABC transporter ATP-binding protein 1327358 oppD 4190236 oppD Escherichia coli 536 oligopeptide ABC transporter ATP-binding protein YP_669205.1 1326345 D 362663 CDS YP_669206.1 110641476 4190237 1327355..1328359 1 NC_008253.1 oligopeptide transport ATP-binding protein OppF 1328359 4190237 ECP_1294 Escherichia coli 536 oligopeptide transport ATP-binding protein OppF YP_669206.1 1327355 D 362663 CDS YP_669207.1 110641477 4190238 complement(1328411..1328740) 1 NC_008253.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1328740 4190238 ECP_1295 Escherichia coli 536 dsDNA-mimic protein YP_669207.1 1328411 R 362663 CDS YP_669208.1 110641478 4190239 complement(1328775..1330235) 1 NC_008253.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1330235 cls 4190239 cls Escherichia coli 536 cardiolipin synthetase YP_669208.1 1328775 R 362663 CDS YP_669209.1 110641479 4190240 1330345..1330551 1 NC_008253.1 hypothetical protein 1330551 4190240 ECP_1297 Escherichia coli 536 hypothetical protein YP_669209.1 1330345 D 362663 CDS YP_669210.1 110641480 4190241 complement(1330606..1331859) 1 NC_008253.1 voltage-gated potassium channel 1331859 4190241 ECP_1298 Escherichia coli 536 voltage-gated potassium channel YP_669210.1 1330606 R 362663 CDS YP_669211.1 110641481 4190242 complement(1332159..1332455) 1 NC_008253.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1332455 4190242 ECP_1299 Escherichia coli 536 hypothetical protein YP_669211.1 1332159 R 362663 CDS YP_669212.1 110641482 4190243 1332664..1333395 1 NC_008253.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1333395 4190243 ECP_1300 Escherichia coli 536 transporter YP_669212.1 1332664 D 362663 CDS YP_669213.1 110641483 4190244 complement(1333435..1333833) 1 NC_008253.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins; acyl-CoA thioester hydrolase 1333833 4190244 ECP_1301 Escherichia coli 536 acyl-CoA thioester hydrolase YP_669213.1 1333435 R 362663 CDS YP_669214.1 110641484 4190245 complement(1333939..1334478) 1 NC_008253.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1334478 4190245 ECP_1302 Escherichia coli 536 intracellular septation protein A YP_669214.1 1333939 R 362663 CDS YP_669215.1 110641485 4190246 complement(1334508..1335251) 1 NC_008253.1 hypothetical protein 1335251 4190246 ECP_1303 Escherichia coli 536 hypothetical protein YP_669215.1 1334508 R 362663 CDS YP_669216.1 110641486 4190247 1335558..1336244 1 NC_008253.1 receptor for colicin S4; outer membrane protein W 1336244 4190247 ECP_1304 Escherichia coli 536 outer membrane protein W YP_669216.1 1335558 D 362663 CDS YP_669217.1 110641487 4190248 complement(1336303..1336809) 1 NC_008253.1 protein YciE 1336809 4190248 ECP_1305 Escherichia coli 536 protein YciE YP_669217.1 1336303 R 362663 CDS YP_669218.1 110641488 4190249 complement(1336855..1337355) 1 NC_008253.1 protein YciF 1337355 4190249 ECP_1306 Escherichia coli 536 protein YciF YP_669218.1 1336855 R 362663 CDS YP_669219.1 110641489 4190250 complement(1337441..1337620) 1 NC_008253.1 hypothetical protein 1337620 4190250 ECP_1307 Escherichia coli 536 hypothetical protein YP_669219.1 1337441 R 362663 CDS YP_669220.1 110641490 4190251 complement(1338001..1338807) 1 NC_008253.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1338807 trpA 4190251 trpA Escherichia coli 536 tryptophan synthase subunit alpha YP_669220.1 1338001 R 362663 CDS YP_669221.1 110641491 4190252 complement(1338807..1340000) 1 NC_008253.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1340000 4190252 ECP_1309 Escherichia coli 536 tryptophan synthase subunit beta YP_669221.1 1338807 R 362663 CDS YP_669222.1 110641492 4190253 complement(1340012..1341370) 1 NC_008253.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1341370 4190253 ECP_1310 Escherichia coli 536 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_669222.1 1340012 R 362663 CDS YP_669223.1 110641493 4190254 complement(1341374..1342969) 1 NC_008253.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1342969 4190254 ECP_1311 Escherichia coli 536 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_669223.1 1341374 R 362663 CDS YP_669224.1 110641494 4189870 complement(1342969..1344531) 1 NC_008253.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1344531 4189870 ECP_1312 Escherichia coli 536 anthranilate synthase component I YP_669224.1 1342969 R 362663 CDS YP_669225.1 110641495 4189871 1344805..1345686 1 NC_008253.1 phosphotransferase domain-containing protein 1345686 4189871 ECP_1313 Escherichia coli 536 phosphotransferase domain-containing protein YP_669225.1 1344805 D 362663 CDS YP_669226.1 110641496 4189872 1345683..1346303 1 NC_008253.1 hypothetical protein 1346303 4189872 ECP_1314 Escherichia coli 536 hypothetical protein YP_669226.1 1345683 D 362663 CDS YP_669227.1 110641497 4189873 1346328..1348220 1 NC_008253.1 membrane protein YciQ 1348220 4189873 ECP_1315 Escherichia coli 536 membrane protein YciQ YP_669227.1 1346328 D 362663 CDS YP_669228.1 110641498 4189874 1348433..1349308 1 NC_008253.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1349308 4189874 ECP_1316 Escherichia coli 536 23S rRNA pseudouridylate synthase B YP_669228.1 1348433 D 362663 CDS YP_669229.1 110641499 4189875 1349478..1350500 1 NC_008253.1 hypothetical protein 1350500 4189875 ECP_1317 Escherichia coli 536 hypothetical protein YP_669229.1 1349478 D 362663 CDS YP_669230.1 110641500 4189876 1350510..1350818 1 NC_008253.1 hypothetical protein 1350818 4189876 ECP_1318 Escherichia coli 536 hypothetical protein YP_669230.1 1350510 D 362663 CDS YP_669231.1 110641501 4189877 complement(1350875..1351465) 1 NC_008253.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1351465 4189877 ECP_1319 Escherichia coli 536 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_669231.1 1350875 R 362663 CDS YP_669232.1 110641502 4189878 complement(1351462..1352220) 1 NC_008253.1 short chain dehydrogenase 1352220 4189878 ECP_1320 Escherichia coli 536 short chain dehydrogenase YP_669232.1 1351462 R 362663 CDS YP_669233.1 110641503 4189879 complement(1352264..1352428) 1 NC_008253.1 hypothetical protein 1352428 4189879 ECP_1321 Escherichia coli 536 hypothetical protein YP_669233.1 1352264 R 362663 CDS YP_669234.1 110641504 4189880 1352440..1353489 1 NC_008253.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1353489 4189880 ECP_1322 Escherichia coli 536 periplasmic protease YP_669234.1 1352440 D 362663 CDS YP_669235.1 110641505 4189881 complement(1353525..1353776) 1 NC_008253.1 hypothetical protein 1353776 4189881 ECP_1323 Escherichia coli 536 hypothetical protein YP_669235.1 1353525 R 362663 CDS YP_669236.1 110641506 4189882 1353821..1354033 1 NC_008253.1 hypothetical protein 1354033 4189882 ECP_1324 Escherichia coli 536 hypothetical protein YP_669236.1 1353821 D 362663 CDS YP_669237.1 110641507 4189883 1354114..1356753 1 NC_008253.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1356753 4189883 ECP_1325 Escherichia coli 536 DNA topoisomerase I YP_669237.1 1354114 D 362663 CDS YP_669238.1 110641508 4189884 1356963..1357937 1 NC_008253.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1357937 cysB 4189884 cysB Escherichia coli 536 transcriptional regulator CysB YP_669238.1 1356963 D 362663 CDS YP_669239.1 110641509 4189885 1358268..1358396 1 NC_008253.1 hypothetical protein 1358396 4189885 ECP_1327 Escherichia coli 536 hypothetical protein YP_669239.1 1358268 D 362663 CDS YP_669240.1 110641510 4189886 1358399..1358566 1 NC_008253.1 hypothetical protein 1358566 4189886 ECP_1328 Escherichia coli 536 hypothetical protein YP_669240.1 1358399 D 362663 CDS YP_669241.1 110641511 4189887 1358925..1361600 1 NC_008253.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1361600 4189887 ECP_1329 Escherichia coli 536 aconitate hydratase YP_669241.1 1358925 D 362663 CDS YP_669242.1 110641512 4189888 complement(1361664..1362254) 1 NC_008253.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1362254 ribA 4189888 ribA Escherichia coli 536 GTP cyclohydrolase II YP_669242.1 1361664 R 362663 CDS YP_669243.1 110641513 4190314 1362424..1363188 1 NC_008253.1 phosphatidylglycerophosphatase B 1363188 4190314 ECP_1331 Escherichia coli 536 phosphatidylglycerophosphatase B YP_669243.1 1362424 D 362663 CDS YP_669244.1 110641514 4190315 1363337..1363645 1 NC_008253.1 hypothetical protein 1363645 4190315 ECP_1332 Escherichia coli 536 hypothetical protein YP_669244.1 1363337 D 362663 CDS YP_669245.1 110641515 4190316 1363652..1364821 1 NC_008253.1 tetratricopeptide repeat protein 1364821 4190316 ECP_1333 Escherichia coli 536 tetratricopeptide repeat protein YP_669245.1 1363652 D 362663 CDS YP_669246.1 110641516 4190317 1365013..1365750 1 NC_008253.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1365750 4190317 ECP_1334 Escherichia coli 536 orotidine 5'-phosphate decarboxylase YP_669246.1 1365013 D 362663 CDS YP_669247.1 110641517 4190318 1365750..1366076 1 NC_008253.1 hypothetical translation initiation factor SUI; involved in start site selection during the initiation of translation; translation initiation factor Sui1 1366076 4190318 ECP_1335 Escherichia coli 536 translation initiation factor Sui1 YP_669247.1 1365750 D 362663 CDS YP_669248.1 110641518 4190319 complement(1366202..1366420) 1 NC_008253.1 lipoprotein 1366420 4190319 ECP_1336 Escherichia coli 536 lipoprotein YP_669248.1 1366202 R 362663 CDS YP_669249.1 110641519 4190320 complement(1366689..1367438) 1 NC_008253.1 regulatory protein YciT 1367438 4190320 ECP_1337 Escherichia coli 536 regulatory protein YciT YP_669249.1 1366689 R 362663 CDS YP_669250.1 110641520 4190321 complement(1367528..1367701) 1 NC_008253.1 hypothetical protein 1367701 4190321 ECP_1338 Escherichia coli 536 hypothetical protein YP_669250.1 1367528 R 362663 CDS YP_669251.1 110641521 4190322 complement(1367849..1369834) 1 NC_008253.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1369834 4190322 ECP_1339 Escherichia coli 536 RNase II stability modulator YP_669251.1 1367849 R 362663 CDS YP_669252.1 110641522 4190323 complement(1370068..1372002) 1 NC_008253.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1372002 4190323 ECP_1340 Escherichia coli 536 exoribonuclease II YP_669252.1 1370068 R 362663 CDS YP_669253.1 110641523 4190324 complement(1372070..1373197) 1 NC_008253.1 hypothetical protein 1373197 4190324 ECP_1341 Escherichia coli 536 hypothetical protein YP_669253.1 1372070 R 362663 CDS YP_669254.1 110641524 4190325 complement(1373342..1374130) 1 NC_008253.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1374130 4190325 ECP_1342 Escherichia coli 536 enoyl-ACP reductase YP_669254.1 1373342 R 362663 CDS YP_669255.1 110641525 4190326 1374608..1375174 1 NC_008253.1 TetR family transcriptional regulator 1375174 4190326 ECP_1343 Escherichia coli 536 TetR family transcriptional regulator YP_669255.1 1374608 D 362663 CDS YP_669256.1 110641526 4190327 1375323..1376444 1 NC_008253.1 multidrug-efflux transport protein 1376444 4190327 ECP_1344 Escherichia coli 536 multidrug-efflux transport protein YP_669256.1 1375323 D 362663 CDS YP_669257.1 110641527 4190328 1376444..1379551 1 NC_008253.1 multidrug efflux protein 1379551 4190328 ECP_1345 Escherichia coli 536 multidrug efflux protein YP_669257.1 1376444 D 362663 CDS YP_669258.1 110641528 4190329 1379555..1380928 1 NC_008253.1 outer membrane efflux lipoprotein 1380928 4190329 ECP_1346 Escherichia coli 536 outer membrane efflux lipoprotein YP_669258.1 1379555 D 362663 CDS YP_669259.1 110641529 4190330 1380937..1382100 1 NC_008253.1 drug transport transmembrane protein 1382100 4190330 ECP_1347 Escherichia coli 536 drug transport transmembrane protein YP_669259.1 1380937 D 362663 CDS YP_669260.1 110641530 4190331 complement(1382148..1382954) 1 NC_008253.1 peptide transport system ATP-binding protein SapF 1382954 4190331 ECP_1348 Escherichia coli 536 peptide transport system ATP-binding protein SapF YP_669260.1 1382148 R 362663 CDS YP_669261.1 110641531 4190332 complement(1382956..1383948) 1 NC_008253.1 peptide transport system ATP-binding protein SapD 1383948 4190332 ECP_1349 Escherichia coli 536 peptide transport system ATP-binding protein SapD YP_669261.1 1382956 R 362663 CDS YP_669262.1 110641532 4190333 complement(1383948..1384838) 1 NC_008253.1 peptide transport system permease SapC 1384838 4190333 ECP_1350 Escherichia coli 536 peptide transport system permease SapC YP_669262.1 1383948 R 362663 CDS YP_669263.1 110641533 4191878 complement(1384825..1385790) 1 NC_008253.1 peptide transport system permease SapB 1385790 4191878 ECP_1351 Escherichia coli 536 peptide transport system permease SapB YP_669263.1 1384825 R 362663 CDS YP_669264.1 110641534 4191879 complement(1385787..1387430) 1 NC_008253.1 peptide transport periplasmic protein SapA 1387430 4191879 ECP_1352 Escherichia coli 536 peptide transport periplasmic protein SapA YP_669264.1 1385787 R 362663 CDS YP_669265.1 110641535 4191880 complement(1387743..1387988) 1 NC_008253.1 hypothetical protein 1387988 4191880 ECP_1353 Escherichia coli 536 hypothetical protein YP_669265.1 1387743 R 362663 CDS YP_669266.1 110641536 4191881 1388102..1388284 1 NC_008253.1 hypothetical protein 1388284 4191881 ECP_1354 Escherichia coli 536 hypothetical protein YP_669266.1 1388102 D 362663 CDS YP_669267.1 110641537 4191882 complement(1388415..1389392) 1 NC_008253.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1389392 pspF 4191882 pspF Escherichia coli 536 phage shock protein operon transcriptional activator YP_669267.1 1388415 R 362663 CDS YP_669268.1 110641538 4191883 1389558..1390226 1 NC_008253.1 negative regulatory gene for the psp opreon; involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1390226 4191883 ECP_1356 Escherichia coli 536 phage shock protein PspA YP_669268.1 1389558 D 362663 CDS YP_669269.1 110641539 4191884 1390280..1390504 1 NC_008253.1 phage shock regulatory protein; acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1390504 pspB 4191884 pspB Escherichia coli 536 phage shock protein B YP_669269.1 1390280 D 362663 CDS YP_669270.1 110641540 4191885 1390504..1390863 1 NC_008253.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1390863 4191885 ECP_1358 Escherichia coli 536 DNA-binding transcriptional activator PspC YP_669270.1 1390504 D 362663 CDS YP_669271.1 110641541 4191886 1390872..1391093 1 NC_008253.1 peripheral inner membrane phage-shock protein 1391093 4191886 ECP_1359 Escherichia coli 536 peripheral inner membrane phage-shock protein YP_669271.1 1390872 D 362663 CDS YP_669272.1 110641542 4191887 1391168..1391482 1 NC_008253.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1391482 4191887 ECP_1360 Escherichia coli 536 thiosulfate:cyanide sulfurtransferase YP_669272.1 1391168 D 362663 CDS YP_669273.1 110641543 4191888 1391665..1393371 1 NC_008253.1 sucrose phosphorylase 1393371 4191888 ECP_1361 Escherichia coli 536 sucrose phosphorylase YP_669273.1 1391665 D 362663 CDS YP_669274.1 110641544 4191889 1393385..1394677 1 NC_008253.1 ABC transporter substrate-binding protein 1394677 4191889 ECP_1362 Escherichia coli 536 ABC transporter substrate-binding protein YP_669274.1 1393385 D 362663 CDS YP_669275.1 110641545 4191890 1394698..1395579 1 NC_008253.1 YcjO protein; binding-protein-dependent transport system inner membrane protein 1395579 4191890 ECP_1363 Escherichia coli 536 binding-protein-dependent transport system inner membrane protein YP_669275.1 1394698 D 362663 CDS YP_669276.1 110641546 4191891 1395566..1396408 1 NC_008253.1 YcjP protein; binding-protein-dependent transport system inner membrane protein 1396408 4191891 ECP_1364 Escherichia coli 536 binding-protein-dependent transport system inner membrane protein YP_669276.1 1395566 D 362663 CDS YP_669277.1 110641547 4191892 1396439..1397491 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YcjQ 1397491 4191892 ECP_1365 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YcjQ YP_669277.1 1396439 D 362663 CDS YP_669278.1 110641548 4191893 1397510..1398298 1 NC_008253.1 hypothetical protein 1398298 4191893 ECP_1366 Escherichia coli 536 hypothetical protein YP_669278.1 1397510 D 362663 CDS YP_669279.1 110641549 4191894 1398320..1399363 1 NC_008253.1 oxidoreductase YcjS 1399363 4191894 ECP_1367 Escherichia coli 536 oxidoreductase YcjS YP_669279.1 1398320 D 362663 CDS YP_669280.1 110641550 4191895 1399360..1401627 1 NC_008253.1 glycosyl hydrolase 1401627 4191895 ECP_1368 Escherichia coli 536 glycosyl hydrolase YP_669280.1 1399360 D 362663 CDS YP_669281.1 110641551 4191896 1401624..1402283 1 NC_008253.1 beta-phosphoglucomutase 1402283 4191896 ECP_1369 Escherichia coli 536 beta-phosphoglucomutase YP_669281.1 1401624 D 362663 CDS YP_669282.1 110641552 4188149 1402297..1402632 1 NC_008253.1 similar to N-terminal part of ATP-binding protein YcjV; ABC transporter 1402632 4188149 ECP_1370 Escherichia coli 536 ABC transporter YP_669282.1 1402297 D 362663 CDS YP_669283.1 110641553 4188150 1402640..1403380 1 NC_008253.1 similar to C-terminal part of ATP-binding protein YcjV; ABC transporter 1403380 4188150 ECP_1371 Escherichia coli 536 ABC transporter YP_669283.1 1402640 D 362663 CDS YP_669284.1 110641554 4188151 1403425..1404330 1 NC_008253.1 outer membrane protein G 1404330 4188151 ECP_1372 Escherichia coli 536 outer membrane protein G YP_669284.1 1403425 D 362663 CDS YP_669285.1 110641555 4188152 complement(1404381..1405379) 1 NC_008253.1 transcriptional regulator YcjW 1405379 4188152 ECP_1373 Escherichia coli 536 transcriptional regulator YcjW YP_669285.1 1404381 R 362663 CDS YP_669286.1 110641556 4188153 1405534..1406931 1 NC_008253.1 hypothetical protein 1406931 4188153 ECP_1374 Escherichia coli 536 hypothetical protein YP_669286.1 1405534 D 362663 CDS YP_669287.1 110641557 4188154 1406928..1407989 1 NC_008253.1 hypothetical protein 1407989 4188154 ECP_1375 Escherichia coli 536 hypothetical protein YP_669287.1 1406928 D 362663 CDS YP_669288.1 110641558 4188155 1408137..1409678 1 NC_008253.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1409678 4188155 ECP_1376 Escherichia coli 536 DNA-binding transcriptional regulator TyrR YP_669288.1 1408137 D 362663 CDS YP_669289.1 110641559 4188156 complement(1409722..1410228) 1 NC_008253.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1410228 tpx 4188156 tpx Escherichia coli 536 thiol peroxidase YP_669289.1 1409722 R 362663 CDS YP_669290.1 110641560 4188157 1410347..1411312 1 NC_008253.1 hypothetical protein YcjG; mandelate racemase/muconate lactonizing enzyme family protein 1411312 4188157 ECP_1378 Escherichia coli 536 mandelate racemase/muconate lactonizing enzyme family protein YP_669290.1 1410347 D 362663 CDS YP_669291.1 110641561 4188158 complement(1411287..1412015) 1 NC_008253.1 murein peptide amidase A 1412015 4188158 ECP_1379 Escherichia coli 536 murein peptide amidase A YP_669291.1 1411287 R 362663 CDS YP_669292.1 110641562 4188159 complement(1412306..1412944) 1 NC_008253.1 hypothetical protein 1412944 4188159 ECP_1380 Escherichia coli 536 hypothetical protein YP_669292.1 1412306 R 362663 CDS YP_669293.1 110641563 4188160 complement(1413015..1413935) 1 NC_008253.1 hypothetical protein 1413935 4188160 ECP_1381 Escherichia coli 536 hypothetical protein YP_669293.1 1413015 R 362663 CDS YP_669294.1 110641564 4188161 1414073..1414972 1 NC_008253.1 LysR family transcriptional regulator 1414972 4188161 ECP_1382 Escherichia coli 536 LysR family transcriptional regulator YP_669294.1 1414073 D 362663 CDS YP_669295.1 110641565 4188164 complement(1416974..1418005) 1 NC_008253.1 hypothetical protein 1418005 4188164 ECP_1385 Escherichia coli 536 hypothetical protein YP_669295.1 1416974 R 362663 CDS YP_669296.1 110641566 4188165 1418249..1418506 1 NC_008253.1 hypothetical protein 1418506 4188165 ECP_1386 Escherichia coli 536 hypothetical protein YP_669296.1 1418249 D 362663 CDS YP_669297.1 110641567 4187564 complement(1418556..1419506) 1 NC_008253.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1419506 4187564 ECP_1387 Escherichia coli 536 universal stress protein UspE YP_669297.1 1418556 R 362663 CDS YP_669298.1 110641568 4187565 complement(1419658..1420452) 1 NC_008253.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1420452 4187565 ECP_1388 Escherichia coli 536 fumarate/nitrate reduction transcriptional regulator YP_669298.1 1419658 R 362663 CDS YP_669299.1 110641569 4187566 complement(1420605..1421120) 1 NC_008253.1 O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1421120 4187566 ECP_1389 Escherichia coli 536 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_669299.1 1420605 R 362663 CDS YP_669300.1 110641570 4187567 complement(1421633..1422448) 1 NC_008253.1 AraC family transcriptional regulator 1422448 4187567 ECP_1390 Escherichia coli 536 AraC family transcriptional regulator YP_669300.1 1421633 R 362663 CDS YP_669301.1 110641571 4187568 1422545..1423573 1 NC_008253.1 multidrug resistance protein A 1423573 4187568 ECP_1391 Escherichia coli 536 multidrug resistance protein A YP_669301.1 1422545 D 362663 CDS YP_669302.1 110641572 4187569 1423570..1425084 1 NC_008253.1 multidrug resistance protein B 1425084 4187569 ECP_1392 Escherichia coli 536 multidrug resistance protein B YP_669302.1 1423570 D 362663 CDS YP_669303.1 110641573 4187570 1425279..1425842 1 NC_008253.1 hypothetical protein 1425842 4187570 ECP_1393 Escherichia coli 536 hypothetical protein YP_669303.1 1425279 D 362663 CDS YP_669304.1 110641574 4187571 complement(1425863..1427095) 1 NC_008253.1 hypothetical protein 1427095 4187571 ECP_1394 Escherichia coli 536 hypothetical protein YP_669304.1 1425863 R 362663 CDS YP_669305.1 110641575 4187572 1427350..1428333 1 NC_008253.1 zinc transporter 1428333 zntB 4187572 zntB Escherichia coli 536 zinc transporter YP_669305.1 1427350 D 362663 CDS YP_669306.1 110641576 4187573 1428608..1428781 1 NC_008253.1 hypothetical protein 1428781 4187573 ECP_1396 Escherichia coli 536 hypothetical protein YP_669306.1 1428608 D 362663 CDS YP_669307.1 110641577 4187574 1428811..1430184 1 NC_008253.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1430184 4187574 ECP_1397 Escherichia coli 536 ATP-dependent RNA helicase DbpA YP_669307.1 1428811 D 362663 CDS YP_669308.1 110641578 4187575 complement(1430313..1431248) 1 NC_008253.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1431248 4187575 ECP_1398 Escherichia coli 536 C32 tRNA thiolase YP_669308.1 1430313 R 362663 CDS YP_669309.1 110641579 4187576 complement(1431300..1431608) 1 NC_008253.1 hypothetical protein 1431608 4187576 ECP_1399 Escherichia coli 536 hypothetical protein YP_669309.1 1431300 R 362663 CDS YP_669310.1 110641580 4187577 complement(1433117..1433485) 1 NC_008253.1 hypothetical protein 1433485 4187577 ECP_1400 Escherichia coli 536 hypothetical protein YP_669310.1 1433117 R 362663 CDS YP_669311.1 110641581 4187578 complement(1433574..1434008) 1 NC_008253.1 universal stress protein 1434008 4187578 ECP_1401 Escherichia coli 536 universal stress protein YP_669311.1 1433574 R 362663 CDS YP_669312.1 110641582 4187579 complement(1434149..1435282) 1 NC_008253.1 outer membrane protein N 1435282 4187579 ECP_1402 Escherichia coli 536 outer membrane protein N YP_669312.1 1434149 R 362663 CDS YP_669313.1 110641583 4187580 complement(1435648..1439172) 1 NC_008253.1 pyruvate-flavodoxin oxidoreductase 1439172 4187580 ECP_1403 Escherichia coli 536 pyruvate-flavodoxin oxidoreductase YP_669313.1 1435648 R 362663 CDS YP_669314.1 110641584 4187581 1439446..1439712 1 NC_008253.1 hypothetical protein 1439712 4187581 ECP_1404 Escherichia coli 536 hypothetical protein YP_669314.1 1439446 D 362663 CDS YP_669315.1 110641585 4187582 complement(1439709..1440131) 1 NC_008253.1 heat-inducible protein 1440131 4187582 ECP_1405 Escherichia coli 536 heat-inducible protein YP_669315.1 1439709 R 362663 CDS YP_669316.1 110641586 4187583 complement(1440242..1441231) 1 NC_008253.1 D-lactate dehydrogenase 1441231 4187583 ECP_1406 Escherichia coli 536 D-lactate dehydrogenase YP_669316.1 1440242 R 362663 CDS YP_669317.1 110641587 4190894 1441439..1444078 1 NC_008253.1 hypothetical protein 1444078 4190894 ECP_1407 Escherichia coli 536 hypothetical protein YP_669317.1 1441439 D 362663 CDS YP_669318.1 110641588 4190895 1444075..1444260 1 NC_008253.1 hypothetical protein 1444260 4190895 ECP_1408 Escherichia coli 536 hypothetical protein YP_669318.1 1444075 D 362663 CDS YP_669319.1 110641589 4190896 1444220..1444594 1 NC_008253.1 hypothetical protein 1444594 4190896 ECP_1409 Escherichia coli 536 hypothetical protein YP_669319.1 1444220 D 362663 CDS YP_669320.1 110641590 4190897 1444970..1452346 1 NC_008253.1 autotransporter/adhesin 1452346 4190897 ECP_1410 Escherichia coli 536 autotransporter/adhesin YP_669320.1 1444970 D 362663 CDS YP_669321.1 110641591 4190898 1452555..1453415 1 NC_008253.1 oxidoreductase 1453415 4190898 ECP_1411 Escherichia coli 536 oxidoreductase YP_669321.1 1452555 D 362663 CDS YP_669322.1 110641592 4190899 complement(1453460..1453684) 1 NC_008253.1 hypothetical protein 1453684 4190899 ECP_1412 Escherichia coli 536 hypothetical protein YP_669322.1 1453460 R 362663 CDS YP_669323.1 110641593 4190900 1453714..1454319 1 NC_008253.1 CDP-alcohol phosphatidyltransferase 1454319 4190900 ECP_1413 Escherichia coli 536 CDP-alcohol phosphatidyltransferase YP_669323.1 1453714 D 362663 CDS YP_669324.1 110641594 4190901 1454493..1455215 1 NC_008253.1 phosphatidate cytidylyltransferase 1455215 4190901 ECP_1414 Escherichia coli 536 phosphatidate cytidylyltransferase YP_669324.1 1454493 D 362663 CDS YP_669325.1 110641595 4190902 1455231..1456988 1 NC_008253.1 hypothetical protein 1456988 4190902 ECP_1415 Escherichia coli 536 hypothetical protein YP_669325.1 1455231 D 362663 CDS YP_669326.1 110641596 4190903 1457334..1458293 1 NC_008253.1 dual specificity phosphatase 1458293 4190903 ECP_1416 Escherichia coli 536 dual specificity phosphatase YP_669326.1 1457334 D 362663 CDS YP_669327.1 110641597 4190904 complement(1458347..1458952) 1 NC_008253.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1458952 4190904 ECP_1417 Escherichia coli 536 azoreductase YP_669327.1 1458347 R 362663 CDS YP_669328.1 110641598 4190905 1459153..1463055 1 NC_008253.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1463055 4190905 ECP_1418 Escherichia coli 536 ATP-dependent RNA helicase HrpA YP_669328.1 1459153 D 362663 CDS YP_669329.1 110641599 4190906 1463328..1464128 1 NC_008253.1 hypothetical protein 1464128 4190906 ECP_1419 Escherichia coli 536 hypothetical protein YP_669329.1 1463328 D 362663 CDS YP_669330.1 110641600 4190907 1464325..1465764 1 NC_008253.1 NAD-linked; aldehyde dehydrogenase 1465764 4190907 ECP_1420 Escherichia coli 536 aldehyde dehydrogenase YP_669330.1 1464325 D 362663 CDS YP_669331.1 110641601 4190908 complement(1465806..1466807) 1 NC_008253.1 glyceraldehyde 3-phosphate dehydrogenase C 1466807 4190908 ECP_1421 Escherichia coli 536 glyceraldehyde 3-phosphate dehydrogenase C YP_669331.1 1465806 R 362663 CDS YP_669332.1 110641602 4190909 1466996..1467526 1 NC_008253.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1467526 4190909 ECP_1422 Escherichia coli 536 cytochrome b561 YP_669332.1 1466996 D 362663 CDS YP_669333.1 110641603 4190910 1467771..1467944 1 NC_008253.1 hypothetical protein 1467944 4190910 ECP_1423 Escherichia coli 536 hypothetical protein YP_669333.1 1467771 D 362663 CDS YP_669335.1 110641605 4188280 complement(1470232..1471155) 1 NC_008253.1 LysR family transcriptional regulator 1471155 4188280 ECP_1427 Escherichia coli 536 LysR family transcriptional regulator YP_669335.1 1470232 R 362663 CDS YP_669336.1 110641606 4188281 1471372..1472715 1 NC_008253.1 hypothetical protein 1472715 4188281 ECP_1428 Escherichia coli 536 hypothetical protein YP_669336.1 1471372 D 362663 CDS YP_669337.1 110641607 4188282 1472976..1474595 1 NC_008253.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1474595 mdoD 4188282 mdoD Escherichia coli 536 glucan biosynthesis protein D YP_669337.1 1472976 D 362663 CDS YP_669338.1 110641608 4188283 1474735..1474959 1 NC_008253.1 hypothetical protein 1474959 4188283 ECP_1430 Escherichia coli 536 hypothetical protein YP_669338.1 1474735 D 362663 CDS YP_669339.1 110641609 4188284 1475022..1475561 1 NC_008253.1 ribosomal-protein-L7/L12-serine acetyltransferase 1475561 4188284 ECP_1431 Escherichia coli 536 ribosomal-protein-L7/L12-serine acetyltransferase YP_669339.1 1475022 D 362663 CDS YP_669340.1 110641610 4188285 complement(1475553..1476533) 1 NC_008253.1 hypothetical protein 1476533 4188285 ECP_1432 Escherichia coli 536 hypothetical protein YP_669340.1 1475553 R 362663 CDS YP_669341.1 110641611 4188286 1476645..1477649 1 NC_008253.1 potassium-tellurite ethidium and proflavin transporter 1477649 4188286 ECP_1433 Escherichia coli 536 potassium-tellurite ethidium and proflavin transporter YP_669341.1 1476645 D 362663 CDS YP_669342.1 110641612 4188287 1477646..1478239 1 NC_008253.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1478239 4188287 ECP_1434 Escherichia coli 536 tellurite resistance protein TehB YP_669342.1 1477646 D 362663 CDS YP_669343.1 110641613 4188288 1478542..1479210 1 NC_008253.1 lipoprotein YdcL 1479210 4188288 ECP_1435 Escherichia coli 536 lipoprotein YdcL YP_669343.1 1478542 D 362663 CDS YP_669344.1 110641614 4188289 complement(1479245..1480510) 1 NC_008253.1 benzoate membrane transport protein 1480510 4188289 ECP_1436 Escherichia coli 536 benzoate membrane transport protein YP_669344.1 1479245 R 362663 CDS YP_669345.1 110641615 4188290 1480509..1481045 1 NC_008253.1 hypothetical protein 1481045 4188290 ECP_1437 Escherichia coli 536 hypothetical protein YP_669345.1 1480509 D 362663 CDS YP_669346.1 110641616 4188291 1481076..1483079 1 NC_008253.1 peptidase 1483079 4188291 ECP_1438 Escherichia coli 536 peptidase YP_669346.1 1481076 D 362663 CDS YP_669347.1 110641617 4188292 complement(1483171..1483401) 1 NC_008253.1 hypothetical protein 1483401 4188292 ECP_1439 Escherichia coli 536 hypothetical protein YP_669347.1 1483171 R 362663 CDS YP_669348.1 110641618 4188293 1483613..1483816 1 NC_008253.1 hypothetical protein 1483816 4188293 ECP_1440 Escherichia coli 536 hypothetical protein YP_669348.1 1483613 D 362663 CDS YP_669349.1 110641619 4188294 1483895..1485301 1 NC_008253.1 GntR family transcriptional regulator 1485301 4188294 ECP_1441 Escherichia coli 536 GntR family transcriptional regulator YP_669349.1 1483895 D 362663 CDS YP_669350.1 110641620 4188295 1485546..1486691 1 NC_008253.1 extracellular solute-binding protein YdcS 1486691 4188295 ECP_1442 Escherichia coli 536 extracellular solute-binding protein YdcS YP_669350.1 1485546 D 362663 CDS YP_669351.1 110641621 4187342 1486709..1487722 1 NC_008253.1 ABC transporter ATP-binding protein 1487722 4187342 ECP_1443 Escherichia coli 536 ABC transporter ATP-binding protein YP_669351.1 1486709 D 362663 CDS YP_669352.1 110641622 4187343 1487723..1488664 1 NC_008253.1 binding-protein-dependent transport system inner membrane protein 1488664 4187343 ECP_1444 Escherichia coli 536 binding-protein-dependent transport system inner membrane protein YP_669352.1 1487723 D 362663 CDS YP_669353.1 110641623 4187344 1488654..1489448 1 NC_008253.1 hypothetical protein 1489448 4187344 ECP_1445 Escherichia coli 536 hypothetical protein YP_669353.1 1488654 D 362663 CDS YP_669354.1 110641624 4187345 1489470..1490894 1 NC_008253.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1490894 4187345 ECP_1446 Escherichia coli 536 gamma-aminobutyraldehyde dehydrogenase YP_669354.1 1489470 D 362663 CDS YP_669355.1 110641625 4187346 1491233..1491454 1 NC_008253.1 inner membrane protein 1491454 4187346 ECP_1447 Escherichia coli 536 inner membrane protein YP_669355.1 1491233 D 362663 CDS YP_669356.1 110641626 4187347 1491540..1491773 1 NC_008253.1 hypothetical protein 1491773 4187347 ECP_1448 Escherichia coli 536 hypothetical protein YP_669356.1 1491540 D 362663 CDS YP_669357.1 110641627 4187348 complement(1491774..1492223) 1 NC_008253.1 hypothetical protein 1492223 4187348 ECP_1449 Escherichia coli 536 hypothetical protein YP_669357.1 1491774 R 362663 CDS YP_669358.1 110641628 4187349 complement(1492220..1492738) 1 NC_008253.1 acetyltransferase YncA 1492738 4187349 ECP_1450 Escherichia coli 536 acetyltransferase YncA YP_669358.1 1492220 R 362663 CDS YP_669359.1 110641629 4187350 1492945..1493181 1 NC_008253.1 hypothetical protein 1493181 4187350 ECP_1451 Escherichia coli 536 hypothetical protein YP_669359.1 1492945 D 362663 CDS YP_669360.1 110641630 4187351 complement(1493219..1495321) 1 NC_008253.1 tonB-dependent receptor YncD 1495321 4187351 ECP_1452 Escherichia coli 536 tonB-dependent receptor YncD YP_669360.1 1493219 R 362663 CDS YP_669361.1 110641631 4187352 1495563..1496624 1 NC_008253.1 hypothetical protein 1496624 4187352 ECP_1453 Escherichia coli 536 hypothetical protein YP_669361.1 1495563 D 362663 CDS YP_669362.1 110641632 4187353 complement(1496737..1498236) 1 NC_008253.1 L-asparagine permease 1498236 4187353 ECP_1454 Escherichia coli 536 L-asparagine permease YP_669362.1 1496737 R 362663 CDS YP_669363.1 110641633 4187354 1498503..1498679 1 NC_008253.1 glutathione S-transferase 1498679 4187354 ECP_1455 Escherichia coli 536 glutathione S-transferase YP_669363.1 1498503 D 362663 CDS YP_669364.1 110641634 4187355 1498693..1499103 1 NC_008253.1 glutathione S-transferase 1499103 4187355 ECP_1456 Escherichia coli 536 glutathione S-transferase YP_669364.1 1498693 D 362663 CDS YP_669365.1 110641635 4187356 1499644..1499928 1 NC_008253.1 hypothetical protein 1499928 4187356 ECP_1457 Escherichia coli 536 hypothetical protein YP_669365.1 1499644 D 362663 CDS YP_669366.1 110641636 4187357 1499947..1502352 1 NC_008253.1 Rhs/Vgr-family protein 1502352 4187357 ECP_1458 Escherichia coli 536 Rhs/Vgr-family protein YP_669366.1 1499947 D 362663 CDS YP_669367.1 110641637 4187358 1502342..1503103 1 NC_008253.1 hypothetical protein 1503103 4187358 ECP_1459 Escherichia coli 536 hypothetical protein YP_669367.1 1502342 D 362663 CDS YP_669368.1 110641638 4187359 1503239..1503418 1 NC_008253.1 hypothetical protein 1503418 4187359 ECP_1460 Escherichia coli 536 hypothetical protein YP_669368.1 1503239 D 362663 CDS YP_669369.1 110641639 4187360 1503472..1503939 1 NC_008253.1 hypothetical protein 1503939 4187360 ECP_1461 Escherichia coli 536 hypothetical protein YP_669369.1 1503472 D 362663 CDS YP_669370.1 110641640 4187361 1504052..1504195 1 NC_008253.1 H repeat-containing Rhs element protein 1504195 4187361 ECP_1462 Escherichia coli 536 H repeat-containing Rhs element protein YP_669370.1 1504052 D 362663 CDS YP_669371.1 110641641 4190996 1504273..1504488 1 NC_008253.1 hypothetical protein 1504488 4190996 ECP_1463 Escherichia coli 536 hypothetical protein YP_669371.1 1504273 D 362663 CDS YP_669372.1 110641642 4190997 complement(1504805..1505374) 1 NC_008253.1 hypothetical protein 1505374 4190997 ECP_1464 Escherichia coli 536 hypothetical protein YP_669372.1 1504805 R 362663 CDS YP_669373.1 110641643 4190998 1505549..1506394 1 NC_008253.1 N-hydroxyarylamine O-acetyltransferase 1506394 4190998 ECP_1465 Escherichia coli 536 N-hydroxyarylamine O-acetyltransferase YP_669373.1 1505549 D 362663 CDS YP_669374.1 110641644 4190999 complement(1506490..1507383) 1 NC_008253.1 hypothetical protein 1507383 4190999 ECP_1466 Escherichia coli 536 hypothetical protein YP_669374.1 1506490 R 362663 CDS YP_669375.1 110641645 4191000 complement(1507463..1508143) 1 NC_008253.1 nitrate reductase 2 subunit gamma 1508143 4191000 ECP_1467 Escherichia coli 536 nitrate reductase 2 subunit gamma YP_669375.1 1507463 R 362663 CDS YP_669376.1 110641646 4191001 complement(1508140..1508835) 1 NC_008253.1 respiratory nitrate reductase 2 subunit delta 1508835 4191001 ECP_1468 Escherichia coli 536 respiratory nitrate reductase 2 subunit delta YP_669376.1 1508140 R 362663 CDS YP_669377.1 110641647 4191002 complement(1508835..1510379) 1 NC_008253.1 respiratory nitrate reductase 2 subunit beta 1510379 4191002 ECP_1469 Escherichia coli 536 respiratory nitrate reductase 2 subunit beta YP_669377.1 1508835 R 362663 CDS YP_669378.1 110641648 4191003 complement(1510376..1514116) 1 NC_008253.1 respiratory nitrate reductase 2 subunit a 1514116 4191003 ECP_1470 Escherichia coli 536 respiratory nitrate reductase 2 subunit a YP_669378.1 1510376 R 362663 CDS YP_669379.1 110641649 4191004 complement(1514211..1515599) 1 NC_008253.1 nitrite extrusion protein 2 1515599 4191004 ECP_1471 Escherichia coli 536 nitrite extrusion protein 2 YP_669379.1 1514211 R 362663 CDS YP_669380.1 110641650 4191005 complement(1515872..1516753) 1 NC_008253.1 hypothetical protein 1516753 4191005 ECP_1472 Escherichia coli 536 hypothetical protein YP_669380.1 1515872 R 362663 CDS YP_669382.1 110641652 4191007 1516986..1517573 1 NC_008253.1 formate dehydrogenase, nitrate-inducible, major subunit 1517573 4191007 ECP_1474 Escherichia coli 536 formate dehydrogenase, nitrate-inducible, major subunit YP_669382.1 1516986 D 362663 CDS YP_669383.1 110641653 4191008 1517622..1520033 1 NC_008253.1 formate dehydrogenase, nitrate-inducible, major subunit 1520033 4191008 ECP_1475 Escherichia coli 536 formate dehydrogenase, nitrate-inducible, major subunit YP_669383.1 1517622 D 362663 CDS YP_669384.1 110641654 4191009 1520052..1520930 1 NC_008253.1 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit 1520930 4191009 ECP_1476 Escherichia coli 536 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit YP_669384.1 1520052 D 362663 CDS YP_669385.1 110641655 4191010 1520905..1521576 1 NC_008253.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1521576 4191010 ECP_1477 Escherichia coli 536 formate dehydrogenase-N subunit gamma YP_669385.1 1520905 D 362663 CDS YP_669386.1 110641656 4191011 complement(1521805..1522089) 1 NC_008253.1 HTH-type transcriptional regulator YddM 1522089 4191011 ECP_1478 Escherichia coli 536 HTH-type transcriptional regulator YddM YP_669386.1 1521805 R 362663 CDS YP_669387.1 110641657 4191012 complement(1522089..1522361) 1 NC_008253.1 hypothetical protein 1522361 4191012 ECP_1479 Escherichia coli 536 hypothetical protein YP_669387.1 1522089 R 362663 CDS YP_669388.1 110641658 4191013 complement(1522553..1523563) 1 NC_008253.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1523563 4191013 ECP_1480 Escherichia coli 536 alcohol dehydrogenase YP_669388.1 1522553 R 362663 CDS YP_669389.1 110641659 4191014 complement(1523697..1525394) 1 NC_008253.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1525394 4191014 ECP_1481 Escherichia coli 536 malate dehydrogenase YP_669389.1 1523697 R 362663 CDS YP_669390.1 110641660 4191858 complement(1525551..1525688) 1 NC_008253.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1525688 rpsV 4191858 rpsV Escherichia coli 536 30S ribosomal subunit S22 YP_669390.1 1525551 R 362663 CDS YP_669391.1 110641661 4191859 complement(1525790..1526005) 1 NC_008253.1 biofilm-dependent modulation protein 1526005 4191859 ECP_1483 Escherichia coli 536 biofilm-dependent modulation protein YP_669391.1 1525790 R 362663 CDS YP_669392.1 110641662 4191860 1526350..1526781 1 NC_008253.1 osmotically inducible protein C 1526781 4191860 ECP_1484 Escherichia coli 536 osmotically inducible protein C YP_669392.1 1526350 D 362663 CDS YP_669393.1 110641663 4191861 complement(1526971..1529370) 1 NC_008253.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1529370 4191861 ECP_1485 Escherichia coli 536 cAMP phosphodiesterase YP_669393.1 1526971 R 362663 CDS YP_669394.1 110641664 4191862 complement(1529395..1529607) 1 NC_008253.1 hypothetical protein 1529607 4191862 ECP_1486 Escherichia coli 536 hypothetical protein YP_669394.1 1529395 R 362663 CDS YP_669395.1 110641665 4191863 complement(1529937..1531256) 1 NC_008253.1 lipoprotein YddW precursor 1531256 4191863 ECP_1487 Escherichia coli 536 lipoprotein YddW precursor YP_669395.1 1529937 R 362663 CDS YP_669396.1 110641666 4191864 complement(1531387..1532922) 1 NC_008253.1 amino acid antiporter 1532922 4191864 ECP_1488 Escherichia coli 536 amino acid antiporter YP_669396.1 1531387 R 362663 CDS YP_669397.1 110641667 4191865 complement(1533078..1534478) 1 NC_008253.1 glutamate decarboxylase 1534478 4191865 ECP_1489 Escherichia coli 536 glutamate decarboxylase YP_669397.1 1533078 R 362663 CDS YP_669398.1 110641668 4191866 complement(1534840..1537623) 1 NC_008253.1 zinc protease PqqL 1537623 4191866 ECP_1490 Escherichia coli 536 zinc protease PqqL YP_669398.1 1534840 R 362663 CDS YP_669399.1 110641669 4191867 complement(1537680..1540052) 1 NC_008253.1 hypothetical protein 1540052 4191867 ECP_1491 Escherichia coli 536 hypothetical protein YP_669399.1 1537680 R 362663 CDS YP_669400.1 110641670 4191868 complement(1540090..1541775) 1 NC_008253.1 ABC transporter ATP-binding protein 1541775 4191868 ECP_1492 Escherichia coli 536 ABC transporter ATP-binding protein YP_669400.1 1540090 R 362663 CDS YP_669401.1 110641671 4191869 complement(1542066..1543223) 1 NC_008253.1 hypothetical protein 1543223 4191869 ECP_1493 Escherichia coli 536 hypothetical protein YP_669401.1 1542066 R 362663 CDS YP_669402.1 110641672 4191870 complement(1543275..1544957) 1 NC_008253.1 sulfatase YdeN 1544957 4191870 ECP_1494 Escherichia coli 536 sulfatase YdeN YP_669402.1 1543275 R 362663 CDS YP_669403.1 110641673 4191871 complement(1545359..1546120) 1 NC_008253.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1546120 4191871 ECP_1495 Escherichia coli 536 transcriptional regulator YdeO YP_669403.1 1545359 R 362663 CDS YP_669404.1 110641674 4191872 complement(1546196..1546393) 1 NC_008253.1 hypothetical protein 1546393 4191872 ECP_1496 Escherichia coli 536 hypothetical protein YP_669404.1 1546196 R 362663 CDS YP_669405.1 110641675 4191873 complement(1546641..1548920) 1 NC_008253.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase; oxidoreductase 1548920 4191873 ECP_1497 Escherichia coli 536 oxidoreductase YP_669405.1 1546641 R 362663 CDS YP_669406.1 110641676 4191874 complement(1549206..1549493) 1 NC_008253.1 fimbrial-like protein 1549493 4191874 ECP_1498 Escherichia coli 536 fimbrial-like protein YP_669406.1 1549206 R 362663 CDS YP_669407.1 110641677 4191875 complement(1549507..1550343) 1 NC_008253.1 fimbrial usher protein 1550343 4191875 ECP_1499 Escherichia coli 536 fimbrial usher protein YP_669407.1 1549507 R 362663 CDS YP_669408.1 110641678 4191876 1550384..1551055 1 NC_008253.1 transcriptional regulator 1551055 4191876 ECP_1500 Escherichia coli 536 transcriptional regulator YP_669408.1 1550384 D 362663 CDS YP_669409.1 110641679 4191877 complement(1551349..1552221) 1 NC_008253.1 hypothetical protein 1552221 4191877 ECP_1501 Escherichia coli 536 hypothetical protein YP_669409.1 1551349 R 362663 CDS YP_669410.1 110641680 4187927 complement(1552221..1552505) 1 NC_008253.1 DNA-binding transcriptional regulator HipB 1552505 4187927 ECP_1502 Escherichia coli 536 DNA-binding transcriptional regulator HipB YP_669410.1 1552221 R 362663 CDS YP_669411.1 110641681 4187928 1552795..1553553 1 NC_008253.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1553553 4187928 ECP_1503 Escherichia coli 536 trans-aconitate 2-methyltransferase YP_669411.1 1552795 D 362663 CDS YP_669412.1 110641682 4187929 complement(1553557..1554471) 1 NC_008253.1 hypothetical protein 1554471 4187929 ECP_1504 Escherichia coli 536 hypothetical protein YP_669412.1 1553557 R 362663 CDS YP_669413.1 110641683 4187930 complement(1554668..1556119) 1 NC_008253.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1556119 4187930 ECP_1505 Escherichia coli 536 altronate oxidoreductase YP_669413.1 1554668 R 362663 CDS YP_669414.1 110641684 4187931 complement(1556346..1557764) 1 NC_008253.1 hypothetical protein 1557764 4187931 ECP_1506 Escherichia coli 536 hypothetical protein YP_669414.1 1556346 R 362663 CDS YP_669415.1 110641685 4187932 complement(1557903..1558262) 1 NC_008253.1 hypothetical protein 1558262 4187932 ECP_1507 Escherichia coli 536 hypothetical protein YP_669415.1 1557903 R 362663 CDS YP_669416.1 110641686 4187933 complement(1558262..1559188) 1 NC_008253.1 catalyzes the formation of glutamate from glutamine; glutaminase 1559188 4187933 ECP_1508 Escherichia coli 536 glutaminase YP_669416.1 1558262 R 362663 CDS YP_669417.1 110641687 4187934 complement(1559252..1560640) 1 NC_008253.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1560640 4187934 ECP_1509 Escherichia coli 536 succinate semialdehyde dehydrogenase YP_669417.1 1559252 R 362663 CDS YP_669418.1 110641688 4187935 1560741..1561622 1 NC_008253.1 transcriptional regulator YneJ 1561622 4187935 ECP_1510 Escherichia coli 536 transcriptional regulator YneJ YP_669418.1 1560741 D 362663 CDS YP_669419.1 110641689 4187936 1561961..1563151 1 NC_008253.1 sugar efflux transporter 1563151 4187936 ECP_1511 Escherichia coli 536 sugar efflux transporter YP_669419.1 1561961 D 362663 CDS YP_669420.1 110641690 4187937 complement(1563176..1563841) 1 NC_008253.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1563841 4187937 ECP_1512 Escherichia coli 536 multiple drug resistance protein MarC YP_669420.1 1563176 R 362663 CDS YP_669421.1 110641691 4187938 1564053..1564487 1 NC_008253.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1564487 4187938 ECP_1513 Escherichia coli 536 DNA-binding transcriptional repressor MarR YP_669421.1 1564053 D 362663 CDS YP_669422.1 110641692 4187939 1564508..1564891 1 NC_008253.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1564891 4187939 ECP_1514 Escherichia coli 536 DNA-binding transcriptional activator MarA YP_669422.1 1564508 D 362663 CDS YP_669423.1 110641693 4187940 1564923..1565141 1 NC_008253.1 hypothetical protein 1565141 4187940 ECP_1515 Escherichia coli 536 hypothetical protein YP_669423.1 1564923 D 362663 CDS YP_669424.1 110641694 4187941 complement(1565198..1566637) 1 NC_008253.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1566637 celA 4187941 celA Escherichia coli 536 6-phospho-beta-glucosidase YP_669424.1 1565198 R 362663 CDS YP_669425.1 110641695 4187942 complement(1566661..1566972) 1 NC_008253.1 hypothetical protein 1566972 4187942 ECP_1517 Escherichia coli 536 hypothetical protein YP_669425.1 1566661 R 362663 CDS YP_669426.1 110641696 4187943 1566980..1567450 1 NC_008253.1 hypothetical protein 1567450 4187943 ECP_1518 Escherichia coli 536 hypothetical protein YP_669426.1 1566980 D 362663 CDS YP_669427.1 110641697 4187944 complement(1567495..1568394) 1 NC_008253.1 O-acetylserine/cysteine export protein 1568394 4187944 ECP_1519 Escherichia coli 536 O-acetylserine/cysteine export protein YP_669427.1 1567495 R 362663 CDS YP_669428.1 110641698 4187945 1568589..1569776 1 NC_008253.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1569776 4187945 ECP_1520 Escherichia coli 536 MFS-type transporter YdeE YP_669428.1 1568589 D 362663 CDS YP_669429.1 110641699 4189391 complement(1570217..1571107) 1 NC_008253.1 hypothetical protein 1571107 4189391 ECP_1521 Escherichia coli 536 hypothetical protein YP_669429.1 1570217 R 362663 CDS YP_669430.1 110641700 4189392 complement(1571614..1573659) 1 NC_008253.1 dipeptidyl carboxypeptidase II 1573659 4189392 ECP_1522 Escherichia coli 536 dipeptidyl carboxypeptidase II YP_669430.1 1571614 R 362663 CDS YP_669431.1 110641701 4189393 1573796..1574542 1 NC_008253.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1574542 4189393 ECP_1523 Escherichia coli 536 3-hydroxy acid dehydrogenase YP_669431.1 1573796 D 362663 CDS YP_669432.1 110641702 4189394 1574631..1575317 1 NC_008253.1 transcriptional regulator YdfH 1575317 4189394 ECP_1524 Escherichia coli 536 transcriptional regulator YdfH YP_669432.1 1574631 D 362663 CDS YP_669433.1 110641703 4189395 1575494..1575697 1 NC_008253.1 hypothetical protein 1575697 4189395 ECP_1525 Escherichia coli 536 hypothetical protein YP_669433.1 1575494 D 362663 CDS YP_669434.1 110641704 4189396 complement(1575733..1577193) 1 NC_008253.1 oxidoreductase YdfI 1577193 4189396 ECP_1526 Escherichia coli 536 oxidoreductase YdfI YP_669434.1 1575733 R 362663 CDS YP_669435.1 110641705 4189397 complement(1577282..1578649) 1 NC_008253.1 metabolite transport protein YdfJ 1578649 4189397 ECP_1527 Escherichia coli 536 metabolite transport protein YdfJ YP_669435.1 1577282 R 362663 CDS YP_669436.1 110641706 4189398 complement(1578707..1579726) 1 NC_008253.1 dehydrogenase 1579726 4189398 ECP_1528 Escherichia coli 536 dehydrogenase YP_669436.1 1578707 R 362663 CDS YP_669437.1 110641707 4189399 complement(1579738..1580952) 1 NC_008253.1 starvation sensing protein RspA 1580952 4189399 ECP_1529 Escherichia coli 536 starvation sensing protein RspA YP_669437.1 1579738 R 362663 CDS YP_669438.1 110641708 4189400 complement(1581158..1581484) 1 NC_008253.1 hypothetical protein 1581484 4189400 ECP_1530 Escherichia coli 536 hypothetical protein YP_669438.1 1581158 R 362663 CDS YP_669439.1 110641709 4189401 1581619..1581960 1 NC_008253.1 hypothetical protein 1581960 4189401 ECP_1531 Escherichia coli 536 hypothetical protein YP_669439.1 1581619 D 362663 CDS YP_669440.1 110641710 4189402 1581995..1582555 1 NC_008253.1 spermidine N1-acetyltransferase 1582555 4189402 ECP_1532 Escherichia coli 536 spermidine N1-acetyltransferase YP_669440.1 1581995 D 362663 CDS YP_669441.1 110641711 4189403 complement(1582558..1583268) 1 NC_008253.1 hypothetical protein 1583268 4189403 ECP_1533 Escherichia coli 536 hypothetical protein YP_669441.1 1582558 R 362663 CDS YP_669442.1 110641712 4189404 1583376..1583681 1 NC_008253.1 hypothetical protein 1583681 4189404 ECP_1534 Escherichia coli 536 hypothetical protein YP_669442.1 1583376 D 362663 CDS YP_669443.1 110641713 4189405 1583938..1584552 1 NC_008253.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1584552 4189405 ECP_1535 Escherichia coli 536 twin-argninine leader-binding protein DmsD YP_669443.1 1583938 D 362663 CDS YP_669444.1 110641714 4189406 1584710..1586002 1 NC_008253.1 voltage-gated ClC-type chloride channel ClcB 1586002 4189406 ECP_1536 Escherichia coli 536 voltage-gated ClC-type chloride channel ClcB YP_669444.1 1584710 D 362663 CDS YP_669445.1 110641715 4189407 complement(1585955..1586650) 1 NC_008253.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1586650 4189407 ECP_1537 Escherichia coli 536 dithiobiotin synthetase YP_669445.1 1585955 R 362663 CDS YP_669446.1 110641716 4189408 complement(1586775..1587995) 1 NC_008253.1 Mlc protein 1587995 4189408 ECP_1538 Escherichia coli 536 Mlc protein YP_669446.1 1586775 R 362663 CDS YP_669447.1 110641717 4189409 complement(1588130..1589023) 1 NC_008253.1 transcriptional regulator YnfL 1589023 4189409 ECP_1539 Escherichia coli 536 transcriptional regulator YnfL YP_669447.1 1588130 R 362663 CDS YP_669448.1 110641718 4189410 1589130..1590383 1 NC_008253.1 transporter 1590383 4189410 ECP_1540 Escherichia coli 536 transporter YP_669448.1 1589130 D 362663 CDS YP_669449.1 110641719 4187323 1590808..1591116 1 NC_008253.1 required for growth and survival under moderately acid conditions; acid shock protein 1591116 4187323 ECP_1541 Escherichia coli 536 acid shock protein YP_669449.1 1590808 D 362663 CDS YP_669450.1 110641720 4187324 1591392..1592213 1 NC_008253.1 protease YdgD 1592213 4187324 ECP_1542 Escherichia coli 536 protease YdgD YP_669450.1 1591392 D 362663 CDS YP_669451.1 110641721 4187325 complement(1592252..1592581) 1 NC_008253.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1592581 4187325 ECP_1543 Escherichia coli 536 multidrug efflux system protein MdtI YP_669451.1 1592252 R 362663 CDS YP_669452.1 110641722 4187326 complement(1592568..1592933) 1 NC_008253.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1592933 4187326 ECP_1544 Escherichia coli 536 multidrug efflux system protein MdtJ YP_669452.1 1592568 R 362663 CDS YP_669453.1 110641723 4187327 1593345..1594379 1 NC_008253.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transporter 1594379 tqsA 4187327 tqsA Escherichia coli 536 transporter YP_669453.1 1593345 D 362663 CDS YP_669454.1 110641724 4187328 complement(1594404..1595792) 1 NC_008253.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1595792 pntB 4187328 pntB Escherichia coli 536 pyridine nucleotide transhydrogenase YP_669454.1 1594404 R 362663 CDS YP_669455.1 110641725 4187329 complement(1595803..1597335) 1 NC_008253.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1597335 pntA 4187329 pntA Escherichia coli 536 NAD(P) transhydrogenase subunit alpha YP_669455.1 1595803 R 362663 CDS YP_669456.1 110641726 4187330 1597859..1598803 1 NC_008253.1 protein YdgH 1598803 4187330 ECP_1548 Escherichia coli 536 protein YdgH YP_669456.1 1597859 D 362663 CDS YP_669457.1 110641727 4187331 1598989..1600371 1 NC_008253.1 arginine/ornithine antiporter 1600371 4187331 ECP_1549 Escherichia coli 536 arginine/ornithine antiporter YP_669457.1 1598989 D 362663 CDS YP_669458.1 110641728 4187332 1600408..1601130 1 NC_008253.1 short chain dehydrogenase 1601130 4187332 ECP_1550 Escherichia coli 536 short chain dehydrogenase YP_669458.1 1600408 D 362663 CDS YP_669459.1 110641729 4187333 complement(1601127..1601462) 1 NC_008253.1 hypothetical protein 1601462 4187333 ECP_1551 Escherichia coli 536 hypothetical protein YP_669459.1 1601127 R 362663 CDS YP_669460.1 110641730 4187334 1601591..1602310 1 NC_008253.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1602310 4187334 ECP_1552 Escherichia coli 536 DNA-binding transcriptional regulator RstA YP_669460.1 1601591 D 362663 CDS YP_669461.1 110641731 4187335 1602314..1603615 1 NC_008253.1 sensor protein RstB 1603615 4187335 ECP_1553 Escherichia coli 536 sensor protein RstB YP_669461.1 1602314 D 362663 CDS YP_669462.1 110641732 4187336 1603691..1604620 1 NC_008253.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1604620 4187336 ECP_1554 Escherichia coli 536 DNA replication terminus site-binding protein YP_669462.1 1603691 D 362663 CDS YP_669463.1 110641733 4187337 complement(1604617..1606020) 1 NC_008253.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1606020 fumC 4187337 fumC Escherichia coli 536 fumarate hydratase YP_669463.1 1604617 R 362663 CDS YP_669464.1 110641734 4187338 complement(1606163..1607809) 1 NC_008253.1 class I fumarate hydratase 1607809 4187338 ECP_1556 Escherichia coli 536 class I fumarate hydratase YP_669464.1 1606163 R 362663 CDS YP_669465.1 110641735 4187339 1608008..1609183 1 NC_008253.1 mannose-6-phosphate isomerase 1609183 4187339 ECP_1557 Escherichia coli 536 mannose-6-phosphate isomerase YP_669465.1 1608008 D 362663 CDS YP_669466.1 110641736 4187340 1609284..1610792 1 NC_008253.1 hypothetical protein 1610792 4187340 ECP_1558 Escherichia coli 536 hypothetical protein YP_669466.1 1609284 D 362663 CDS YP_669467.1 110641737 4187341 complement(1610837..1612102) 1 NC_008253.1 outer membrane porin protein 1612102 4187341 ECP_1559 Escherichia coli 536 outer membrane porin protein YP_669467.1 1610837 R 362663 CDS YP_669468.1 110641738 4187963 complement(1612141..1613514) 1 NC_008253.1 glucuronide transporter 1613514 4187963 ECP_1560 Escherichia coli 536 glucuronide transporter YP_669468.1 1612141 R 362663 CDS YP_669469.1 110641739 4187964 complement(1613511..1615322) 1 NC_008253.1 beta-D-glucuronidase 1615322 4187964 ECP_1561 Escherichia coli 536 beta-D-glucuronidase YP_669469.1 1613511 R 362663 CDS YP_669470.1 110641740 4187965 complement(1615712..1616302) 1 NC_008253.1 uid operon repressor 1616302 4187965 ECP_1562 Escherichia coli 536 uid operon repressor YP_669470.1 1615712 R 362663 CDS YP_669471.1 110641741 4187966 complement(1616531..1617298) 1 NC_008253.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1617298 4187966 ECP_1563 Escherichia coli 536 7-alpha-hydroxysteroid dehydrogenase YP_669471.1 1616531 R 362663 CDS YP_669472.1 110641742 4187967 complement(1617411..1618439) 1 NC_008253.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1618439 4187967 ECP_1564 Escherichia coli 536 DNA-binding transcriptional repressor MalI YP_669472.1 1617411 R 362663 CDS YP_669473.1 110641743 4187968 1618614..1620206 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; PTS system maltose and glucose-specific transporter subunit IICB 1620206 4187968 ECP_1565 Escherichia coli 536 PTS system maltose and glucose-specific transporter subunit IICB YP_669473.1 1618614 D 362663 CDS YP_669474.1 110641744 4187969 1620216..1621388 1 NC_008253.1 MalY protein 1621388 4187969 ECP_1566 Escherichia coli 536 MalY protein YP_669474.1 1620216 D 362663 CDS YP_669475.1 110641745 4187970 1621492..1622493 1 NC_008253.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1622493 4187970 ECP_1567 Escherichia coli 536 adenosine deaminase YP_669475.1 1621492 D 362663 CDS YP_669476.1 110641746 4187971 complement(1622529..1623569) 1 NC_008253.1 oxidoreductase 1623569 4187971 ECP_1568 Escherichia coli 536 oxidoreductase YP_669476.1 1622529 R 362663 CDS YP_669477.1 110641747 4187972 1623782..1623937 1 NC_008253.1 beta-lactam resistance protein 1623937 4187972 ECP_1569 Escherichia coli 536 beta-lactam resistance protein YP_669477.1 1623782 D 362663 CDS YP_669478.1 110641748 4187973 1624210..1624425 1 NC_008253.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1624425 4187973 ECP_1570 Escherichia coli 536 oriC-binding nucleoid-associated protein YP_669478.1 1624210 D 362663 CDS YP_669479.1 110641749 4187974 1624511..1624951 1 NC_008253.1 hypothetical protein 1624951 4187974 ECP_1571 Escherichia coli 536 hypothetical protein YP_669479.1 1624511 D 362663 CDS YP_669480.1 110641750 4187975 1625028..1625609 1 NC_008253.1 Na(+)-translocating NADH-quinone reductase subunit E 1625609 4187975 ECP_1572 Escherichia coli 536 Na(+)-translocating NADH-quinone reductase subunit E YP_669480.1 1625028 D 362663 CDS YP_669481.1 110641751 4187976 1625609..1626187 1 NC_008253.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1626187 4187976 ECP_1573 Escherichia coli 536 electron transport complex protein RnfB YP_669481.1 1625609 D 362663 CDS YP_669482.1 110641752 4187977 1626180..1628504 1 NC_008253.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1628504 4187977 ECP_1574 Escherichia coli 536 electron transport complex protein RnfC YP_669482.1 1626180 D 362663 CDS YP_669483.1 110641753 4187978 1628505..1629563 1 NC_008253.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1629563 rnfD 4187978 rnfD Escherichia coli 536 electron transport complex protein RnfD YP_669483.1 1628505 D 362663 CDS YP_669484.1 110641754 4187979 1629567..1630187 1 NC_008253.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1630187 4187979 ECP_1576 Escherichia coli 536 electron transport complex protein RnfG YP_669484.1 1629567 D 362663 CDS YP_669485.1 110641755 4187980 1630191..1630886 1 NC_008253.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1630886 4187980 ECP_1577 Escherichia coli 536 electron transport complex protein RsxE YP_669485.1 1630191 D 362663 CDS YP_669486.1 110641756 4187981 1630886..1631521 1 NC_008253.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1631521 4187981 ECP_1578 Escherichia coli 536 endonuclease III YP_669486.1 1630886 D 362663 CDS YP_669487.1 110641757 4187982 1632131..1633633 1 NC_008253.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1633633 tppB 4187982 tppB Escherichia coli 536 tripeptide transporter permease YP_669487.1 1632131 D 362663 CDS YP_669488.1 110641758 4190462 1633739..1634344 1 NC_008253.1 glutathionine S-transferase 1634344 4190462 ECP_1580 Escherichia coli 536 glutathionine S-transferase YP_669488.1 1633739 D 362663 CDS YP_669489.1 110641759 4190463 complement(1634388..1635248) 1 NC_008253.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1635248 4190463 ECP_1581 Escherichia coli 536 pyridoxamine kinase YP_669489.1 1634388 R 362663 CDS YP_669490.1 110641760 4190466 complement(1636713..1637369) 1 NC_008253.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1637369 4190466 ECP_1584 Escherichia coli 536 pyridoxamine 5'-phosphate oxidase YP_669490.1 1636713 R 362663 CDS YP_669491.1 110641761 4190467 complement(1637428..1637751) 1 NC_008253.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1637751 4190467 ECP_1585 Escherichia coli 536 lysozyme inhibitor YP_669491.1 1637428 R 362663 CDS YP_669492.1 110641762 4190468 complement(1637855..1638964) 1 NC_008253.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1638964 anmK 4190468 anmK Escherichia coli 536 anhydro-N-acetylmuramic acid kinase YP_669492.1 1637855 R 362663 CDS YP_669493.1 110641763 4190469 1639238..1639705 1 NC_008253.1 outer membrane lipoprotein 1639705 4190469 ECP_1587 Escherichia coli 536 outer membrane lipoprotein YP_669493.1 1639238 D 362663 CDS YP_669494.1 110641764 4190470 complement(1639752..1640192) 1 NC_008253.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1640192 4190470 ECP_1588 Escherichia coli 536 transcriptional regulator SlyA YP_669494.1 1639752 R 362663 CDS YP_669495.1 110641765 4190471 1640395..1640622 1 NC_008253.1 hypothetical protein 1640622 4190471 ECP_1589 Escherichia coli 536 hypothetical protein YP_669495.1 1640395 D 362663 CDS YP_669496.1 110641766 4190472 1640625..1641482 1 NC_008253.1 hypothetical protein 1641482 4190472 ECP_1590 Escherichia coli 536 hypothetical protein YP_669496.1 1640625 D 362663 CDS YP_669497.1 110641767 4190473 1641482..1643494 1 NC_008253.1 hypothetical protein 1643494 4190473 ECP_1591 Escherichia coli 536 hypothetical protein YP_669497.1 1641482 D 362663 CDS YP_669498.1 110641768 4190474 complement(1643495..1644031) 1 NC_008253.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1644031 4190474 ECP_1592 Escherichia coli 536 superoxide dismutase YP_669498.1 1643495 R 362663 CDS YP_669499.1 110641769 4190475 complement(1644097..1644993) 1 NC_008253.1 aldo/keto reductase 1644993 4190475 ECP_1593 Escherichia coli 536 aldo/keto reductase YP_669499.1 1644097 R 362663 CDS YP_669500.1 110641770 4190476 complement(1645042..1645419) 1 NC_008253.1 hypothetical protein 1645419 4190476 ECP_1594 Escherichia coli 536 hypothetical protein YP_669500.1 1645042 R 362663 CDS YP_669501.1 110641771 4190477 1645384..1645983 1 NC_008253.1 transcriptional regulator YdhM 1645983 4190477 ECP_1595 Escherichia coli 536 transcriptional regulator YdhM YP_669501.1 1645384 D 362663 CDS YP_669502.1 110641772 4190478 1646020..1647117 1 NC_008253.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1647117 4190478 ECP_1596 Escherichia coli 536 N-ethylmaleimide reductase YP_669502.1 1646020 D 362663 CDS YP_669503.1 110641773 4190407 1647198..1647605 1 NC_008253.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1647605 4190407 ECP_1597 Escherichia coli 536 glyoxalase I YP_669503.1 1647198 D 362663 CDS YP_669504.1 110641774 4190408 1647708..1648355 1 NC_008253.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1648355 4190408 ECP_1598 Escherichia coli 536 ribonuclease T YP_669504.1 1647708 D 362663 CDS YP_669505.1 110641775 4190409 complement(1648727..1649074) 1 NC_008253.1 hypothetical protein 1649074 4190409 ECP_1599 Escherichia coli 536 hypothetical protein YP_669505.1 1648727 R 362663 CDS YP_669506.1 110641776 4190410 1649409..1650224 1 NC_008253.1 lipoprotein 1650224 4190410 ECP_1600 Escherichia coli 536 lipoprotein YP_669506.1 1649409 D 362663 CDS YP_669507.1 110641777 4190411 1650352..1650933 1 NC_008253.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1650933 4190411 ECP_1601 Escherichia coli 536 superoxide dismutase YP_669507.1 1650352 D 362663 CDS YP_669508.1 110641778 4190412 complement(1651079..1652248) 1 NC_008253.1 transport transmembrane protein 1652248 4190412 ECP_1602 Escherichia coli 536 transport transmembrane protein YP_669508.1 1651079 R 362663 CDS YP_669509.1 110641779 4190413 complement(1652414..1652503) 1 NC_008253.1 hypothetical protein 1652503 4190413 ECP_1603 Escherichia coli 536 hypothetical protein YP_669509.1 1652414 R 362663 CDS YP_669510.1 110641780 4190414 1652590..1652814 1 NC_008253.1 hypothetical protein 1652814 4190414 ECP_1604 Escherichia coli 536 hypothetical protein YP_669510.1 1652590 D 362663 CDS YP_669511.1 110641781 4190415 1652802..1653827 1 NC_008253.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1653827 4190415 ECP_1605 Escherichia coli 536 DNA-binding transcriptional repressor PurR YP_669511.1 1652802 D 362663 CDS YP_669512.1 110641782 4190416 complement(1653824..1654756) 1 NC_008253.1 DNA-binding transcriptional regulator 1654756 4190416 ECP_1606 Escherichia coli 536 DNA-binding transcriptional regulator YP_669512.1 1653824 R 362663 CDS YP_669513.1 110641783 4190417 1654869..1656080 1 NC_008253.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1656080 4190417 ECP_1607 Escherichia coli 536 inner membrane transport protein YdhC YP_669513.1 1654869 D 362663 CDS YP_669514.1 110641784 4190418 1656371..1657519 1 NC_008253.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1657519 4190418 ECP_1608 Escherichia coli 536 cyclopropane-fatty-acyl-phospholipid synthase YP_669514.1 1656371 D 362663 CDS YP_669515.1 110641785 4190419 complement(1657559..1658200) 1 NC_008253.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1658200 4190419 ECP_1609 Escherichia coli 536 riboflavin synthase subunit alpha YP_669515.1 1657559 R 362663 CDS YP_669516.1 110641786 4190420 1658415..1659788 1 NC_008253.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1659788 4190420 ECP_1610 Escherichia coli 536 multidrug efflux protein YP_669516.1 1658415 D 362663 CDS YP_669517.1 110641787 4190421 complement(1659829..1661085) 1 NC_008253.1 hypothetical protein 1661085 4190421 ECP_1611 Escherichia coli 536 hypothetical protein YP_669517.1 1659829 R 362663 CDS YP_669518.1 110641788 4190537 1661660..1661965 1 NC_008253.1 hypothetical protein 1661965 4190537 ECP_1614 Escherichia coli 536 hypothetical protein YP_669518.1 1661660 D 362663 CDS YP_669519.1 110641789 4190538 1662091..1663701 1 NC_008253.1 hypothetical protein 1663701 4190538 ECP_1615 Escherichia coli 536 hypothetical protein YP_669519.1 1662091 D 362663 CDS YP_669520.1 110641790 4190539 complement(1663707..1664471) 1 NC_008253.1 hypothetical protein 1664471 4190539 ECP_1616 Escherichia coli 536 hypothetical protein YP_669520.1 1663707 R 362663 CDS YP_669521.1 110641791 4190540 complement(1664523..1665308) 1 NC_008253.1 PhsC-like protein 1665308 4190540 ECP_1617 Escherichia coli 536 PhsC-like protein YP_669521.1 1664523 R 362663 CDS YP_669522.1 110641792 4190541 complement(1665305..1665973) 1 NC_008253.1 ferredoxin-like protein YdhX 1665973 4190541 ECP_1618 Escherichia coli 536 ferredoxin-like protein YdhX YP_669522.1 1665305 R 362663 CDS YP_669523.1 110641793 4190542 complement(1666037..1666675) 1 NC_008253.1 hypothetical protein 1666675 4190542 ECP_1619 Escherichia coli 536 hypothetical protein YP_669523.1 1666037 R 362663 CDS YP_669524.1 110641794 4190543 complement(1666688..1668790) 1 NC_008253.1 oxidoreductase 1668790 4190543 ECP_1620 Escherichia coli 536 oxidoreductase YP_669524.1 1666688 R 362663 CDS YP_669525.1 110641795 4190544 complement(1668811..1669437) 1 NC_008253.1 hypothetical protein 1669437 4190544 ECP_1621 Escherichia coli 536 hypothetical protein YP_669525.1 1668811 R 362663 CDS YP_669526.1 110641796 4190545 complement(1669893..1670102) 1 NC_008253.1 hypothetical protein 1670102 4190545 ECP_1622 Escherichia coli 536 hypothetical protein YP_669526.1 1669893 R 362663 CDS YP_669527.1 110641797 4190546 1670443..1672071 1 NC_008253.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1672071 4190546 ECP_1623 Escherichia coli 536 pyruvate kinase YP_669527.1 1670443 D 362663 CDS YP_669528.1 110641798 4190547 1672382..1672618 1 NC_008253.1 major outer membrane lipoprotein 1672618 4190547 ECP_1624 Escherichia coli 536 major outer membrane lipoprotein YP_669528.1 1672382 D 362663 CDS YP_669529.1 110641799 4190548 complement(1672681..1673685) 1 NC_008253.1 hypothetical protein 1673685 4190548 ECP_1625 Escherichia coli 536 hypothetical protein YP_669529.1 1672681 R 362663 CDS YP_669530.1 110641800 4190549 complement(1673834..1674250) 1 NC_008253.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1674250 4190549 ECP_1626 Escherichia coli 536 cysteine desufuration protein SufE YP_669530.1 1673834 R 362663 CDS YP_669531.1 110641801 4190550 complement(1674263..1675483) 1 NC_008253.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1675483 4190550 ECP_1627 Escherichia coli 536 bifunctional cysteine desulfurase/selenocysteine lyase YP_669531.1 1674263 R 362663 CDS YP_669532.1 110641802 4190551 complement(1675480..1676751) 1 NC_008253.1 required for stability of iron-sulfur component of FhuF; with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1676751 4190551 ECP_1628 Escherichia coli 536 cysteine desulfurase activator complex subunit SufD YP_669532.1 1675480 R 362663 CDS YP_669533.1 110641803 4190552 complement(1676726..1677472) 1 NC_008253.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 1677472 sufC 4190552 sufC Escherichia coli 536 cysteine desulfurase YP_669533.1 1676726 R 362663 CDS YP_669534.1 110641804 4190553 complement(1677482..1678969) 1 NC_008253.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1678969 4190553 ECP_1630 Escherichia coli 536 cysteine desulfurase activator complex subunit SufB YP_669534.1 1677482 R 362663 CDS YP_669535.1 110641805 4190554 complement(1678978..1679346) 1 NC_008253.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1679346 sufA 4190554 sufA Escherichia coli 536 iron-sulfur cluster assembly scaffold protein YP_669535.1 1678978 R 362663 CDS YP_669536.1 110641806 4190555 complement(1679895..1680083) 1 NC_008253.1 hypothetical protein 1680083 4190555 ECP_1632 Escherichia coli 536 hypothetical protein YP_669536.1 1679895 R 362663 CDS YP_669537.1 110641807 4190556 complement(1680183..1680593) 1 NC_008253.1 hypothetical protein 1680593 4190556 ECP_1633 Escherichia coli 536 hypothetical protein YP_669537.1 1680183 R 362663 CDS YP_669538.1 110641808 4188394 complement(1680590..1683646) 1 NC_008253.1 oxidase 1683646 4188394 ECP_1634 Escherichia coli 536 oxidase YP_669538.1 1680590 R 362663 CDS YP_669539.1 110641809 4188395 1683860..1684972 1 NC_008253.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1684972 4188395 ECP_1635 Escherichia coli 536 inner membrane protein YP_669539.1 1683860 D 362663 CDS YP_669540.1 110641810 4188396 1685401..1685757 1 NC_008253.1 hypothetical protein 1685757 4188396 ECP_1636 Escherichia coli 536 hypothetical protein YP_669540.1 1685401 D 362663 CDS YP_669541.1 110641811 4188397 1685857..1687071 1 NC_008253.1 transporter 1687071 4188397 ECP_1637 Escherichia coli 536 transporter YP_669541.1 1685857 D 362663 CDS YP_669542.1 110641812 4188398 1687298..1688563 1 NC_008253.1 transporter 1688563 4188398 ECP_1638 Escherichia coli 536 transporter YP_669542.1 1687298 D 362663 CDS YP_669543.1 110641813 4188399 1688575..1689441 1 NC_008253.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1689441 4188399 ECP_1639 Escherichia coli 536 quinate/shikimate dehydrogenase YP_669543.1 1688575 D 362663 CDS YP_669544.1 110641814 4188400 1689472..1690230 1 NC_008253.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1690230 aroD 4188400 aroD Escherichia coli 536 3-dehydroquinate dehydratase YP_669544.1 1689472 D 362663 CDS YP_669545.1 110641815 4188401 1690375..1691970 1 NC_008253.1 hypothetical protein 1691970 4188401 ECP_1641 Escherichia coli 536 hypothetical protein YP_669545.1 1690375 D 362663 CDS YP_669546.1 110641816 4188402 1691981..1693135 1 NC_008253.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1693135 4188402 ECP_1642 Escherichia coli 536 acyl-CoA dehydrogenase YP_669546.1 1691981 D 362663 CDS YP_669547.1 110641817 4188403 complement(1693178..1694089) 1 NC_008253.1 transcriptional regulator YdiP 1694089 4188403 ECP_1643 Escherichia coli 536 transcriptional regulator YdiP YP_669547.1 1693178 R 362663 CDS YP_669548.1 110641818 4188404 1694405..1695169 1 NC_008253.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1695169 4188404 ECP_1644 Escherichia coli 536 electron transfer flavoprotein YdiQ YP_669548.1 1694405 D 362663 CDS YP_669549.1 110641819 4188405 1695189..1696127 1 NC_008253.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1696127 4188405 ECP_1645 Escherichia coli 536 electron transfer flavoprotein subunit YdiR YP_669549.1 1695189 D 362663 CDS YP_669550.1 110641820 4188406 1696182..1697471 1 NC_008253.1 hypothetical protein 1697471 4188406 ECP_1646 Escherichia coli 536 hypothetical protein YP_669550.1 1696182 D 362663 CDS YP_669551.1 110641821 4188407 1697468..1697761 1 NC_008253.1 ferredoxin-like protein YdiT 1697761 4188407 ECP_1647 Escherichia coli 536 ferredoxin-like protein YdiT YP_669551.1 1697468 D 362663 CDS YP_669552.1 110641822 4188408 1697764..1699464 1 NC_008253.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1699464 4188408 ECP_1648 Escherichia coli 536 short chain acyl-CoA synthetase YP_669552.1 1697764 D 362663 CDS YP_669553.1 110641823 4188409 complement(1699521..1701899) 1 NC_008253.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1701899 4188409 ECP_1649 Escherichia coli 536 phosphoenolpyruvate synthase YP_669553.1 1699521 R 362663 CDS YP_669554.1 110641824 4188410 complement(1701953..1702120) 1 NC_008253.1 hypothetical protein 1702120 4188410 ECP_1650 Escherichia coli 536 hypothetical protein YP_669554.1 1701953 R 362663 CDS YP_669555.1 110641825 4188411 1702232..1703065 1 NC_008253.1 hypothetical protein 1703065 4188411 ECP_1651 Escherichia coli 536 hypothetical protein YP_669555.1 1702232 D 362663 CDS YP_669556.1 110641826 4188412 1703222..1704268 1 NC_008253.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1704268 4188412 ECP_1652 Escherichia coli 536 phospho-2-dehydro-3-deoxyheptonate aldolase YP_669556.1 1703222 D 362663 CDS YP_669557.1 110641827 4190837 1704400..1704591 1 NC_008253.1 hypothetical protein 1704591 4190837 ECP_1653 Escherichia coli 536 hypothetical protein YP_669557.1 1704400 D 362663 CDS YP_669558.1 110641828 4190838 complement(1704595..1706031) 1 NC_008253.1 hypothetical protein 1706031 4190838 ECP_1654 Escherichia coli 536 hypothetical protein YP_669558.1 1704595 R 362663 CDS YP_669559.1 110641829 4190839 complement(1706094..1706807) 1 NC_008253.1 hypothetical protein 1706807 4190839 ECP_1655 Escherichia coli 536 hypothetical protein YP_669559.1 1706094 R 362663 CDS YP_669560.1 110641830 4190840 complement(1707054..1707518) 1 NC_008253.1 lipoprotein NlpC 1707518 4190840 ECP_1656 Escherichia coli 536 lipoprotein NlpC YP_669560.1 1707054 R 362663 CDS YP_669561.1 110641831 4190841 complement(1707596..1708345) 1 NC_008253.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1708345 4190841 ECP_1657 Escherichia coli 536 vitamin B12-transporter ATPase YP_669561.1 1707596 R 362663 CDS YP_669562.1 110641832 4190842 complement(1708345..1708896) 1 NC_008253.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 1708896 btuE 4190842 btuE Escherichia coli 536 glutathione peroxidase YP_669562.1 1708345 R 362663 CDS YP_669563.1 110641833 4190843 complement(1708958..1709938) 1 NC_008253.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1709938 4190843 ECP_1659 Escherichia coli 536 vtamin B12-transporter permease YP_669563.1 1708958 R 362663 CDS YP_669564.1 110641834 4190844 complement(1710039..1710338) 1 NC_008253.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1710338 ihfA 4190844 ihfA Escherichia coli 536 integration host factor subunit alpha YP_669564.1 1710039 R 362663 CDS YP_669565.1 110641835 4190845 complement(1710343..1712730) 1 NC_008253.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1712730 pheT 4190845 pheT Escherichia coli 536 phenylalanyl-tRNA synthetase subunit beta YP_669565.1 1710343 R 362663 CDS YP_669566.1 110641836 4190846 complement(1712745..1713728) 1 NC_008253.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1713728 pheS 4190846 pheS Escherichia coli 536 phenylalanyl-tRNA synthetase subunit alpha YP_669566.1 1712745 R 362663 CDS YP_669567.1 110641837 4190847 complement(1714179..1714535) 1 NC_008253.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1714535 rplT 4190847 rplT Escherichia coli 536 50S ribosomal protein L20 YP_669567.1 1714179 R 362663 CDS YP_669568.1 110641838 4190848 complement(1714588..1714785) 1 NC_008253.1 50S ribosomal protein L35 1714785 rpmI 4190848 rpmI Escherichia coli 536 50S ribosomal protein L35 YP_669568.1 1714588 R 362663 CDS YP_669569.1 110641839 4190849 complement(1714882..1715316) 1 NC_008253.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1715316 infC 4190849 infC Escherichia coli 536 translation initiation factor IF-3 YP_669569.1 1714882 R 362663 CDS YP_669570.1 110641840 4190850 complement(1715428..1717356) 1 NC_008253.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1717356 4190850 ECP_1666 Escherichia coli 536 threonyl-tRNA synthetase YP_669570.1 1715428 R 362663 CDS YP_669571.1 110641841 4190851 1718042..1718407 1 NC_008253.1 hypothetical protein 1718407 4190851 ECP_1667 Escherichia coli 536 hypothetical protein YP_669571.1 1718042 D 362663 CDS YP_669572.1 110641842 4190852 1718362..1718763 1 NC_008253.1 hypothetical protein 1718763 4190852 ECP_1668 Escherichia coli 536 hypothetical protein YP_669572.1 1718362 D 362663 CDS YP_669573.1 110641843 4190853 complement(1719241..1719999) 1 NC_008253.1 hypothetical protein 1719999 4190853 ECP_1669 Escherichia coli 536 hypothetical protein YP_669573.1 1719241 R 362663 CDS YP_669574.1 110641844 4190854 1720286..1721215 1 NC_008253.1 6-phosphofructokinase 1721215 4190854 ECP_1670 Escherichia coli 536 6-phosphofructokinase YP_669574.1 1720286 D 362663 CDS YP_669575.1 110641845 4190855 1721316..1721606 1 NC_008253.1 hypothetical protein 1721606 4190855 ECP_1671 Escherichia coli 536 hypothetical protein YP_669575.1 1721316 D 362663 CDS YP_669576.1 110641846 4190856 1721712..1722572 1 NC_008253.1 fructosamine kinase 1722572 4190856 ECP_1672 Escherichia coli 536 fructosamine kinase YP_669576.1 1721712 D 362663 CDS YP_669577.1 110641847 4191307 complement(1722613..1723149) 1 NC_008253.1 hypothetical protein 1723149 4191307 ECP_1673 Escherichia coli 536 hypothetical protein YP_669577.1 1722613 R 362663 CDS YP_669578.1 110641848 4191308 1723296..1723964 1 NC_008253.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1723964 4191308 ECP_1674 Escherichia coli 536 2-deoxyglucose-6-phosphatase YP_669578.1 1723296 D 362663 CDS YP_669579.1 110641849 4191309 1724128..1724718 1 NC_008253.1 hypothetical protein 1724718 4191309 ECP_1675 Escherichia coli 536 hypothetical protein YP_669579.1 1724128 D 362663 CDS YP_669580.1 110641850 4191310 1724851..1726242 1 NC_008253.1 sodium:dicarboxylate symporter YdjN 1726242 4191310 ECP_1676 Escherichia coli 536 sodium:dicarboxylate symporter YdjN YP_669580.1 1724851 D 362663 CDS YP_669581.1 110641851 4191311 complement(1726289..1726531) 1 NC_008253.1 cell division modulator 1726531 4191311 ECP_1677 Escherichia coli 536 cell division modulator YP_669581.1 1726289 R 362663 CDS YP_669582.1 110641852 4191312 1726735..1728996 1 NC_008253.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1728996 katE 4191312 katE Escherichia coli 536 hydroperoxidase II YP_669582.1 1726735 D 362663 CDS YP_669583.1 110641853 4191313 complement(1729043..1729801) 1 NC_008253.1 hypothetical protein 1729801 4191313 ECP_1679 Escherichia coli 536 hypothetical protein YP_669583.1 1729043 R 362663 CDS YP_669584.1 110641854 4191314 complement(1729814..1731166) 1 NC_008253.1 6-phospho-beta-glucosidase 1731166 4191314 ECP_1680 Escherichia coli 536 6-phospho-beta-glucosidase YP_669584.1 1729814 R 362663 CDS YP_669585.1 110641855 4191315 complement(1731270..1732109) 1 NC_008253.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1732109 4191315 ECP_1681 Escherichia coli 536 DNA-binding transcriptional regulator ChbR YP_669585.1 1731270 R 362663 CDS YP_669586.1 110641856 4191316 complement(1732120..1732470) 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1732470 4191316 ECP_1682 Escherichia coli 536 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_669586.1 1732120 R 362663 CDS YP_669587.1 110641857 4191317 complement(1732521..1733879) 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1733879 4191317 ECP_1683 Escherichia coli 536 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_669587.1 1732521 R 362663 CDS YP_669588.1 110641858 4191318 complement(1733964..1734284) 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1734284 4191318 ECP_1684 Escherichia coli 536 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_669588.1 1733964 R 362663 CDS YP_669589.1 110641859 4191319 complement(1734584..1734922) 1 NC_008253.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1734922 4191319 ECP_1685 Escherichia coli 536 DNA-binding transcriptional activator OsmE YP_669589.1 1734584 R 362663 CDS YP_669590.1 110641860 4191320 1735124..1735951 1 NC_008253.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1735951 nadE 4191320 nadE Escherichia coli 536 NAD synthetase YP_669590.1 1735124 D 362663 CDS YP_669591.1 110641861 4191321 1736181..1737068 1 NC_008253.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1737068 4191321 ECP_1687 Escherichia coli 536 nucleotide excision repair endonuclease YP_669591.1 1736181 D 362663 CDS YP_669592.1 110641862 4191322 complement(1737028..1737603) 1 NC_008253.1 hypothetical protein 1737603 4191322 ECP_1688 Escherichia coli 536 hypothetical protein YP_669592.1 1737028 R 362663 CDS YP_669593.1 110641863 4191323 complement(1737806..1738291) 1 NC_008253.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1738291 4191323 ECP_1689 Escherichia coli 536 hypothetical protein YP_669593.1 1737806 R 362663 CDS YP_669594.1 110641864 4191324 complement(1738621..1739589) 1 NC_008253.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1739589 4191324 ECP_1690 Escherichia coli 536 succinylglutamate desuccinylase YP_669594.1 1738621 R 362663 CDS YP_669595.1 110641865 4191325 complement(1739582..1740925) 1 NC_008253.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1740925 4191325 ECP_1691 Escherichia coli 536 succinylarginine dihydrolase YP_669595.1 1739582 R 362663 CDS YP_669596.1 110641866 4188432 complement(1740922..1742400) 1 NC_008253.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1742400 astD 4188432 astD Escherichia coli 536 succinylglutamic semialdehyde dehydrogenase YP_669596.1 1740922 R 362663 CDS YP_669597.1 110641867 4188433 complement(1742397..1743431) 1 NC_008253.1 arginine succinyltransferase 1743431 4188433 ECP_1693 Escherichia coli 536 arginine succinyltransferase YP_669597.1 1742397 R 362663 CDS YP_669598.1 110641868 4188434 complement(1743428..1744648) 1 NC_008253.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1744648 4188434 ECP_1694 Escherichia coli 536 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_669598.1 1743428 R 362663 CDS YP_669599.1 110641869 4188435 1745082..1745900 1 NC_008253.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1745900 4188435 ECP_1695 Escherichia coli 536 exonuclease III YP_669599.1 1745082 D 362663 CDS YP_669600.1 110641870 4188436 1746067..1746777 1 NC_008253.1 hypothetical protein 1746777 4188436 ECP_1696 Escherichia coli 536 hypothetical protein YP_669600.1 1746067 D 362663 CDS YP_669601.1 110641871 4188437 1746782..1747459 1 NC_008253.1 hypothetical protein 1747459 4188437 ECP_1697 Escherichia coli 536 hypothetical protein YP_669601.1 1746782 D 362663 CDS YP_669602.1 110641872 4188438 1747473..1748180 1 NC_008253.1 hypothetical protein 1748180 4188438 ECP_1698 Escherichia coli 536 hypothetical protein YP_669602.1 1747473 D 362663 CDS YP_669603.1 110641873 4188439 1748180..1748728 1 NC_008253.1 hypothetical protein 1748728 4188439 ECP_1699 Escherichia coli 536 hypothetical protein YP_669603.1 1748180 D 362663 CDS YP_669604.1 110641874 4188440 1748738..1749904 1 NC_008253.1 ABC transporter substrate-binding protein 1749904 4188440 ECP_1700 Escherichia coli 536 ABC transporter substrate-binding protein YP_669604.1 1748738 D 362663 CDS YP_669605.1 110641875 4188441 1749877..1751412 1 NC_008253.1 ABC transporter permease 1751412 4188441 ECP_1701 Escherichia coli 536 ABC transporter permease YP_669605.1 1749877 D 362663 CDS YP_669606.1 110641876 4188442 1751412..1752065 1 NC_008253.1 ABC transporter ATP-binding protein 1752065 4188442 ECP_1702 Escherichia coli 536 ABC transporter ATP-binding protein YP_669606.1 1751412 D 362663 CDS YP_669607.1 110641877 4188443 1752368..1753441 1 NC_008253.1 thiosulfate sulfurtransferase 1753441 4188443 ECP_1703 Escherichia coli 536 thiosulfate sulfurtransferase YP_669607.1 1752368 D 362663 CDS YP_669608.1 110641878 4188444 complement(1753450..1754070) 1 NC_008253.1 hypothetical protein 1754070 4188444 ECP_1704 Escherichia coli 536 hypothetical protein YP_669608.1 1753450 R 362663 CDS YP_669609.1 110641879 4188445 1754157..1754564 1 NC_008253.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1754564 4188445 ECP_1705 Escherichia coli 536 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_669609.1 1754157 D 362663 CDS YP_669610.1 110641880 4188446 complement(1754530..1754802) 1 NC_008253.1 hypothetical protein 1754802 4188446 ECP_1706 Escherichia coli 536 hypothetical protein YP_669610.1 1754530 R 362663 CDS YP_669611.1 110641881 4188447 1755038..1756381 1 NC_008253.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1756381 4188447 ECP_1707 Escherichia coli 536 glutamate dehydrogenase YP_669611.1 1755038 D 362663 CDS YP_669612.1 110641882 4188448 complement(1756437..1758380) 1 NC_008253.1 hypothetical protein 1758380 4188448 ECP_1708 Escherichia coli 536 hypothetical protein YP_669612.1 1756437 R 362663 CDS YP_669613.1 110641883 4188449 complement(1758408..1760357) 1 NC_008253.1 hypothetical protein 1760357 4188449 ECP_1709 Escherichia coli 536 hypothetical protein YP_669613.1 1758408 R 362663 CDS YP_669614.1 110641884 4188450 complement(1760354..1762054) 1 NC_008253.1 chaperone protein HscC 1762054 4188450 ECP_1710 Escherichia coli 536 chaperone protein HscC YP_669614.1 1760354 R 362663 CDS YP_669615.1 110641885 4188451 complement(1762422..1764368) 1 NC_008253.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1764368 4188451 ECP_1711 Escherichia coli 536 DNA topoisomerase III YP_669615.1 1762422 R 362663 CDS YP_669616.1 110641886 4191897 complement(1764373..1765416) 1 NC_008253.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1765416 4191897 ECP_1712 Escherichia coli 536 selenophosphate synthetase YP_669616.1 1764373 R 362663 CDS YP_669617.1 110641887 4191898 complement(1765533..1766084) 1 NC_008253.1 hypothetical protein 1766084 4191898 ECP_1713 Escherichia coli 536 hypothetical protein YP_669617.1 1765533 R 362663 CDS YP_669618.1 110641888 4191899 1766245..1768101 1 NC_008253.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1768101 4191899 ECP_1714 Escherichia coli 536 protease 4 YP_669618.1 1766245 D 362663 CDS YP_669619.1 110641889 4191900 1768268..1769284 1 NC_008253.1 converts asparagine to aspartate and ammonia; asparaginase 1769284 ansA 4191900 ansA Escherichia coli 536 asparaginase YP_669619.1 1768268 D 362663 CDS YP_669620.1 110641890 4191901 1769295..1769936 1 NC_008253.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1769936 4191901 ECP_1716 Escherichia coli 536 nicotinamidase/pyrazinamidase YP_669620.1 1769295 D 362663 CDS YP_669621.1 110641891 4191902 complement(1770029..1771387) 1 NC_008253.1 metabolite transport protein YdjE 1771387 4191902 ECP_1717 Escherichia coli 536 metabolite transport protein YdjE YP_669621.1 1770029 R 362663 CDS YP_669622.1 110641892 4191903 complement(1771505..1772263) 1 NC_008253.1 transcriptional regulator YdjF 1772263 4191903 ECP_1718 Escherichia coli 536 transcriptional regulator YdjF YP_669622.1 1771505 R 362663 CDS YP_669623.1 110641893 4191904 complement(1772400..1773380) 1 NC_008253.1 oxidoreductase YdjG 1773380 4191904 ECP_1719 Escherichia coli 536 oxidoreductase YdjG YP_669623.1 1772400 R 362663 CDS YP_669624.1 110641894 4191905 complement(1773390..1774358) 1 NC_008253.1 sugar kinase 1774358 4191905 ECP_1720 Escherichia coli 536 sugar kinase YP_669624.1 1773390 R 362663 CDS YP_669625.1 110641895 4191906 complement(1774342..1775178) 1 NC_008253.1 hypothetical protein 1775178 4191906 ECP_1721 Escherichia coli 536 hypothetical protein YP_669625.1 1774342 R 362663 CDS YP_669626.1 110641896 4191907 complement(1775199..1776203) 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YdjJ 1776203 4191907 ECP_1722 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YdjJ YP_669626.1 1775199 R 362663 CDS YP_669627.1 110641897 4191908 complement(1776259..1777638) 1 NC_008253.1 metabolite transport protein YdjK 1777638 4191908 ECP_1723 Escherichia coli 536 metabolite transport protein YdjK YP_669627.1 1776259 R 362663 CDS YP_669628.1 110641898 4191909 complement(1777665..1778741) 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YdjL 1778741 4191909 ECP_1724 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YdjL YP_669628.1 1777665 R 362663 CDS YP_669629.1 110641899 4191910 complement(1779111..1779383) 1 NC_008253.1 hypothetical protein 1779383 4191910 ECP_1725 Escherichia coli 536 hypothetical protein YP_669629.1 1779111 R 362663 CDS YP_669630.1 110641900 4191911 complement(1779425..1779838) 1 NC_008253.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1779838 4191911 ECP_1726 Escherichia coli 536 methionine sulfoxide reductase B YP_669630.1 1779425 R 362663 CDS YP_669631.1 110641901 4191912 1780180..1781175 1 NC_008253.1 glyceraldehyde 3-phosphate dehydrogenase A 1781175 4191912 ECP_1727 Escherichia coli 536 glyceraldehyde 3-phosphate dehydrogenase A YP_669631.1 1780180 D 362663 CDS YP_669632.1 110641902 4191913 1781259..1782143 1 NC_008253.1 aldose 1-epimerase 1782143 4191913 ECP_1728 Escherichia coli 536 aldose 1-epimerase YP_669632.1 1781259 D 362663 CDS YP_669633.1 110641903 4191914 complement(1782194..1783048) 1 NC_008253.1 hypothetical protein 1783048 4191914 ECP_1729 Escherichia coli 536 hypothetical protein YP_669633.1 1782194 R 362663 CDS YP_669634.1 110641904 4191915 complement(1783138..1783884) 1 NC_008253.1 MltA-interacting protein 1783884 4191915 ECP_1730 Escherichia coli 536 MltA-interacting protein YP_669634.1 1783138 R 362663 CDS YP_669635.1 110641905 4191956 1784320..1786254 1 NC_008253.1 hypothetical protein 1786254 4191956 ECP_1731 Escherichia coli 536 hypothetical protein YP_669635.1 1784320 D 362663 CDS YP_669636.1 110641906 4191957 1786367..1787650 1 NC_008253.1 hypothetical protein 1787650 4191957 ECP_1732 Escherichia coli 536 hypothetical protein YP_669636.1 1786367 D 362663 CDS YP_669637.1 110641907 4191958 1787797..1789272 1 NC_008253.1 hypothetical protein 1789272 4191958 ECP_1733 Escherichia coli 536 hypothetical protein YP_669637.1 1787797 D 362663 CDS YP_669638.1 110641908 4191959 1789453..1790943 1 NC_008253.1 hypothetical protein 1790943 4191959 ECP_1734 Escherichia coli 536 hypothetical protein YP_669638.1 1789453 D 362663 CDS YP_669639.1 110641909 4191960 1790986..1791489 1 NC_008253.1 hypothetical protein 1791489 4191960 ECP_1735 Escherichia coli 536 hypothetical protein YP_669639.1 1790986 D 362663 CDS YP_669640.1 110641910 4191961 1791764..1792210 1 NC_008253.1 hypothetical protein 1792210 4191961 ECP_1736 Escherichia coli 536 hypothetical protein YP_669640.1 1791764 D 362663 CDS YP_669641.1 110641911 4191962 complement(1792167..1792988) 1 NC_008253.1 transcriptional regulator YeaM 1792988 4191962 ECP_1737 Escherichia coli 536 transcriptional regulator YeaM YP_669641.1 1792167 R 362663 CDS YP_669642.1 110641912 4191963 1793085..1794266 1 NC_008253.1 transporter 1794266 4191963 ECP_1738 Escherichia coli 536 transporter YP_669642.1 1793085 D 362663 CDS YP_669643.1 110641913 4191964 1794321..1794668 1 NC_008253.1 hypothetical protein 1794668 4191964 ECP_1739 Escherichia coli 536 hypothetical protein YP_669643.1 1794321 D 362663 CDS YP_669644.1 110641914 4191965 complement(1794690..1794944) 1 NC_008253.1 hypothetical protein 1794944 4191965 ECP_1740 Escherichia coli 536 hypothetical protein YP_669644.1 1794690 R 362663 CDS YP_669645.1 110641915 4191966 1795127..1796152 1 NC_008253.1 hypothetical protein 1796152 4191966 ECP_1741 Escherichia coli 536 hypothetical protein YP_669645.1 1795127 D 362663 CDS YP_669646.1 110641916 4191967 complement(1796419..1796667) 1 NC_008253.1 hypothetical protein 1796667 4191967 ECP_1742 Escherichia coli 536 hypothetical protein YP_669646.1 1796419 R 362663 CDS YP_669647.1 110641917 4191968 complement(1796815..1796997) 1 NC_008253.1 hypothetical protein 1796997 4191968 ECP_1743 Escherichia coli 536 hypothetical protein YP_669647.1 1796815 R 362663 CDS YP_669648.1 110641918 4191969 complement(1797001..1797360) 1 NC_008253.1 hypothetical protein 1797360 4191969 ECP_1744 Escherichia coli 536 hypothetical protein YP_669648.1 1797001 R 362663 CDS YP_669649.1 110641919 4191970 complement(1797533..1798171) 1 NC_008253.1 leucine export protein LeuE 1798171 4191970 ECP_1745 Escherichia coli 536 leucine export protein LeuE YP_669649.1 1797533 R 362663 CDS YP_669650.1 110641920 4191971 complement(1798298..1798630) 1 NC_008253.1 hypothetical protein 1798630 4191971 ECP_1746 Escherichia coli 536 hypothetical protein YP_669650.1 1798298 R 362663 CDS YP_669651.1 110641921 4191972 complement(1798714..1799829) 1 NC_008253.1 ribonuclease D 1799829 4191972 ECP_1747 Escherichia coli 536 ribonuclease D YP_669651.1 1798714 R 362663 CDS YP_669652.1 110641922 4191973 complement(1799911..1801629) 1 NC_008253.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1801629 4191973 ECP_1748 Escherichia coli 536 long-chain-fatty-acid--CoA ligase YP_669652.1 1799911 R 362663 CDS YP_669653.1 110641923 4191974 complement(1801801..1802382) 1 NC_008253.1 Slp family outer membrane lipoprotein 1802382 4191974 ECP_1749 Escherichia coli 536 Slp family outer membrane lipoprotein YP_669653.1 1801801 R 362663 CDS YP_669654.1 110641924 4191975 complement(1802422..1803117) 1 NC_008253.1 protease YeaZ 1803117 4191975 ECP_1750 Escherichia coli 536 protease YeaZ YP_669654.1 1802422 R 362663 CDS YP_669655.1 110641925 4188375 complement(1803175..1805085) 1 NC_008253.1 ATP-dependent helicase YoaA 1805085 4188375 ECP_1751 Escherichia coli 536 ATP-dependent helicase YoaA YP_669655.1 1803175 R 362663 CDS YP_669656.1 110641926 4188376 1805214..1805561 1 NC_008253.1 hypothetical protein 1805561 4188376 ECP_1752 Escherichia coli 536 hypothetical protein YP_669656.1 1805214 D 362663 CDS YP_669657.1 110641927 4188377 1805983..1806282 1 NC_008253.1 hypothetical protein 1806282 4188377 ECP_1753 Escherichia coli 536 hypothetical protein YP_669657.1 1805983 D 362663 CDS YP_669658.1 110641928 4188378 complement(1806402..1806581) 1 NC_008253.1 hypothetical protein 1806581 4188378 ECP_1754 Escherichia coli 536 hypothetical protein YP_669658.1 1806402 R 362663 CDS YP_669659.1 110641929 4188379 1806655..1808016 1 NC_008253.1 para-aminobenzoate synthase component I 1808016 4188379 ECP_1755 Escherichia coli 536 para-aminobenzoate synthase component I YP_669659.1 1806655 D 362663 CDS YP_669660.1 110641930 4188380 1808020..1808598 1 NC_008253.1 hypothetical protein 1808598 4188380 ECP_1756 Escherichia coli 536 hypothetical protein YP_669660.1 1808020 D 362663 CDS YP_669661.1 110641931 4188381 1808782..1810146 1 NC_008253.1 L-serine dehydratase 1 1810146 4188381 ECP_1757 Escherichia coli 536 L-serine dehydratase 1 YP_669661.1 1808782 D 362663 CDS YP_669662.1 110641932 4188382 1810277..1811875 1 NC_008253.1 hypothetical protein 1811875 4188382 ECP_1758 Escherichia coli 536 hypothetical protein YP_669662.1 1810277 D 362663 CDS YP_669663.1 110641933 4188383 complement(1811879..1813435) 1 NC_008253.1 hypothetical protein 1813435 4188383 ECP_1759 Escherichia coli 536 hypothetical protein YP_669663.1 1811879 R 362663 CDS YP_669664.1 110641934 4188384 1813898..1814869 1 NC_008253.1 PTS system mannose-specific transporter subunit IIAB 1814869 4188384 ECP_1760 Escherichia coli 536 PTS system mannose-specific transporter subunit IIAB YP_669664.1 1813898 D 362663 CDS YP_669665.1 110641935 4188385 1814932..1815732 1 NC_008253.1 PTS system mannose-specific transporter subunit IIC 1815732 4188385 ECP_1761 Escherichia coli 536 PTS system mannose-specific transporter subunit IIC YP_669665.1 1814932 D 362663 CDS YP_669666.1 110641936 4188386 1815745..1816596 1 NC_008253.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; mannose-specific PTS system protein IID 1816596 4188386 ECP_1762 Escherichia coli 536 mannose-specific PTS system protein IID YP_669666.1 1815745 D 362663 CDS YP_669667.1 110641937 4188387 1816651..1817109 1 NC_008253.1 hypothetical protein 1817109 4188387 ECP_1763 Escherichia coli 536 hypothetical protein YP_669667.1 1816651 D 362663 CDS YP_669668.1 110641938 4188388 1817538..1818104 1 NC_008253.1 membrane protein YebN; hypothetical protein 1818104 4188388 ECP_1764 Escherichia coli 536 hypothetical protein YP_669668.1 1817538 D 362663 CDS YP_669669.1 110641939 4188389 complement(1818101..1818910) 1 NC_008253.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 1818910 rrmA 4188389 rrmA Escherichia coli 536 23S rRNA methyltransferase YP_669669.1 1818101 R 362663 CDS YP_669670.1 110641940 4188390 complement(1819076..1819285) 1 NC_008253.1 cold shock-like protein CspC 1819285 4188390 ECP_1766 Escherichia coli 536 cold shock-like protein CspC YP_669670.1 1819076 R 362663 CDS YP_669671.1 110641941 4188391 complement(1819298..1819441) 1 NC_008253.1 hypothetical protein 1819441 4188391 ECP_1767 Escherichia coli 536 hypothetical protein YP_669671.1 1819298 R 362663 CDS YP_669672.1 110641942 4188392 complement(1820111..1820398) 1 NC_008253.1 hypothetical protein 1820398 4188392 ECP_1768 Escherichia coli 536 hypothetical protein YP_669672.1 1820111 R 362663 CDS YP_669674.1 110641944 4191780 1820775..1821014 1 NC_008253.1 hypothetical protein 1821014 4191780 ECP_1770 Escherichia coli 536 hypothetical protein YP_669674.1 1820775 D 362663 CDS YP_669675.1 110641945 4191781 complement(1821158..1821949) 1 NC_008253.1 transcriptional regulator KdgR 1821949 4191781 ECP_1771 Escherichia coli 536 transcriptional regulator KdgR YP_669675.1 1821158 R 362663 CDS YP_669676.1 110641946 4191782 1822126..1823499 1 NC_008253.1 transporter 1823499 4191782 ECP_1772 Escherichia coli 536 transporter YP_669676.1 1822126 D 362663 CDS YP_669677.1 110641947 4191783 complement(1823545..1824426) 1 NC_008253.1 metalloprotease; heat shock protein HtpX 1824426 4191783 ECP_1773 Escherichia coli 536 heat shock protein HtpX YP_669677.1 1823545 R 362663 CDS YP_669678.1 110641948 4191784 complement(1824618..1826666) 1 NC_008253.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1826666 4191784 ECP_1774 Escherichia coli 536 carboxy-terminal protease YP_669678.1 1824618 R 362663 CDS YP_669679.1 110641949 4191785 complement(1826686..1827384) 1 NC_008253.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1827384 4191785 ECP_1775 Escherichia coli 536 solute/DNA competence effector YP_669679.1 1826686 R 362663 CDS YP_669680.1 110641950 4191786 complement(1827481..1827978) 1 NC_008253.1 GAF domain-containing protein 1827978 4191786 ECP_1776 Escherichia coli 536 GAF domain-containing protein YP_669680.1 1827481 R 362663 CDS YP_669681.1 110641951 4191787 1828108..1829391 1 NC_008253.1 hypothetical protein 1829391 4191787 ECP_1777 Escherichia coli 536 hypothetical protein YP_669681.1 1828108 D 362663 CDS YP_669682.1 110641952 4191788 1829360..1831993 1 NC_008253.1 hypothetical protein 1831993 4191788 ECP_1778 Escherichia coli 536 hypothetical protein YP_669682.1 1829360 D 362663 CDS YP_669683.1 110641953 4191789 1832067..1833512 1 NC_008253.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1833512 yebU 4191789 yebU Escherichia coli 536 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_669683.1 1832067 D 362663 CDS YP_669684.1 110641954 4191790 1833630..1833866 1 NC_008253.1 hypothetical protein 1833866 4191790 ECP_1780 Escherichia coli 536 hypothetical protein YP_669684.1 1833630 D 362663 CDS YP_669685.1 110641955 4191791 1833971..1834162 1 NC_008253.1 hypothetical protein 1834162 4191791 ECP_1781 Escherichia coli 536 hypothetical protein YP_669685.1 1833971 D 362663 CDS YP_669686.1 110641956 4191792 complement(1834163..1834819) 1 NC_008253.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1834819 pphA 4191792 pphA Escherichia coli 536 serine/threonine protein phosphatase 1 YP_669686.1 1834163 R 362663 CDS YP_669687.1 110641957 4191793 complement(1835214..1835555) 1 NC_008253.1 hypothetical protein 1835555 4191793 ECP_1783 Escherichia coli 536 hypothetical protein YP_669687.1 1835214 R 362663 CDS YP_669688.1 110641958 4191794 complement(1835568..1836440) 1 NC_008253.1 hypothetical protein 1836440 4191794 ECP_1784 Escherichia coli 536 hypothetical protein YP_669688.1 1835568 R 362663 CDS YP_669689.1 110641959 4191795 complement(1836444..1836818) 1 NC_008253.1 hypothetical protein 1836818 4191795 ECP_1785 Escherichia coli 536 hypothetical protein YP_669689.1 1836444 R 362663 CDS YP_669690.1 110641960 4191796 1836870..1837187 1 NC_008253.1 DNA polymerase III subunit theta 1837187 4191796 ECP_1786 Escherichia coli 536 DNA polymerase III subunit theta YP_669690.1 1836870 D 362663 CDS YP_669691.1 110641961 4191797 1837290..1837946 1 NC_008253.1 hypothetical protein 1837946 4191797 ECP_1787 Escherichia coli 536 hypothetical protein YP_669691.1 1837290 D 362663 CDS YP_669692.1 110641962 4191798 1837970..1838632 1 NC_008253.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1838632 4191798 ECP_1788 Escherichia coli 536 exodeoxyribonuclease X YP_669692.1 1837970 D 362663 CDS YP_669693.1 110641963 4191799 complement(1838629..1840689) 1 NC_008253.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1840689 4191799 ECP_1789 Escherichia coli 536 protease 2 YP_669693.1 1838629 R 362663 CDS YP_669694.1 110641964 4189811 complement(1840898..1841557) 1 NC_008253.1 hypothetical protein 1841557 4189811 ECP_1790 Escherichia coli 536 hypothetical protein YP_669694.1 1840898 R 362663 CDS YP_669695.1 110641965 4189812 complement(1841884..1842240) 1 NC_008253.1 secreted protein; unknown function; hypothetical protein 1842240 4189812 ECP_1791 Escherichia coli 536 hypothetical protein YP_669695.1 1841884 R 362663 CDS YP_669696.1 110641966 4189813 complement(1842307..1842597) 1 NC_008253.1 DNA damage-inducible protein YebG 1842597 4189813 ECP_1792 Escherichia coli 536 DNA damage-inducible protein YebG YP_669696.1 1842307 R 362663 CDS YP_669697.1 110641967 4189814 1842731..1843909 1 NC_008253.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1843909 purT 4189814 purT Escherichia coli 536 phosphoribosylglycinamide formyltransferase 2 YP_669697.1 1842731 D 362663 CDS YP_669698.1 110641968 4189815 complement(1843965..1844606) 1 NC_008253.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1844606 4189815 ECP_1794 Escherichia coli 536 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_669698.1 1843965 R 362663 CDS YP_669699.1 110641969 4189816 complement(1844643..1846454) 1 NC_008253.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1846454 4189816 ECP_1795 Escherichia coli 536 phosphogluconate dehydratase YP_669699.1 1844643 R 362663 CDS YP_669700.1 110641970 4189817 complement(1846689..1848164) 1 NC_008253.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1848164 4189817 ECP_1796 Escherichia coli 536 glucose-6-phosphate 1-dehydrogenase YP_669700.1 1846689 R 362663 CDS YP_669701.1 110641971 4189818 1848502..1849371 1 NC_008253.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1849371 4189818 ECP_1797 Escherichia coli 536 DNA-binding transcriptional regulator HexR YP_669701.1 1848502 D 362663 CDS YP_669702.1 110641972 4189819 1849499..1850941 1 NC_008253.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1850941 4189819 ECP_1798 Escherichia coli 536 pyruvate kinase YP_669702.1 1849499 D 362663 CDS YP_669703.1 110641973 4189820 complement(1851073..1852044) 1 NC_008253.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1852044 4189820 ECP_1799 Escherichia coli 536 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_669703.1 1851073 R 362663 CDS YP_669704.1 110641974 4189821 complement(1852163..1853485) 1 NC_008253.1 hypothetical protein 1853485 4189821 ECP_1800 Escherichia coli 536 hypothetical protein YP_669704.1 1852163 R 362663 CDS YP_669705.1 110641975 4189822 complement(1853501..1854487) 1 NC_008253.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1854487 znuA 4189822 znuA Escherichia coli 536 high-affinity zinc transporter periplasmic protein YP_669705.1 1853501 R 362663 CDS YP_669706.1 110641976 4189823 1854512..1855267 1 NC_008253.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1855267 znuC 4189823 znuC Escherichia coli 536 high-affinity zinc transporter ATPase YP_669706.1 1854512 D 362663 CDS YP_669707.1 110641977 4189824 1855264..1856049 1 NC_008253.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1856049 znuB 4189824 znuB Escherichia coli 536 high-affinity zinc transporter membrane protein YP_669707.1 1855264 D 362663 CDS YP_669708.1 110641978 4189825 complement(1856197..1857207) 1 NC_008253.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1857207 ruvB 4189825 ruvB Escherichia coli 536 Holliday junction DNA helicase RuvB YP_669708.1 1856197 R 362663 CDS YP_669709.1 110641979 4189826 complement(1857216..1857827) 1 NC_008253.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1857827 ruvA 4189826 ruvA Escherichia coli 536 Holliday junction DNA helicase RuvA YP_669709.1 1857216 R 362663 CDS YP_669710.1 110641980 4189827 1858104..1858706 1 NC_008253.1 hypothetical protein 1858706 4189827 ECP_1806 Escherichia coli 536 hypothetical protein YP_669710.1 1858104 D 362663 CDS YP_669711.1 110641981 4189828 complement(1858708..1859229) 1 NC_008253.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1859229 ruvC 4189828 ruvC Escherichia coli 536 Holliday junction resolvase YP_669711.1 1858708 R 362663 CDS YP_669712.1 110641982 4189829 complement(1859264..1860004) 1 NC_008253.1 hypothetical protein 1860004 4189829 ECP_1808 Escherichia coli 536 hypothetical protein YP_669712.1 1859264 R 362663 CDS YP_669713.1 110641983 4188772 complement(1860033..1860476) 1 NC_008253.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1860476 ntpA 4188772 ntpA Escherichia coli 536 dATP pyrophosphohydrolase YP_669713.1 1860033 R 362663 CDS YP_669714.1 110641984 4188773 complement(1860478..1862250) 1 NC_008253.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1862250 aspS 4188773 aspS Escherichia coli 536 aspartyl-tRNA synthetase YP_669714.1 1860478 R 362663 CDS YP_669715.1 110641985 4188774 1862560..1863126 1 NC_008253.1 hypothetical protein 1863126 4188774 ECP_1811 Escherichia coli 536 hypothetical protein YP_669715.1 1862560 D 362663 CDS YP_669716.1 110641986 4188775 1863123..1863941 1 NC_008253.1 hypothetical protein 1863941 4188775 ECP_1812 Escherichia coli 536 hypothetical protein YP_669716.1 1863123 D 362663 CDS YP_669717.1 110641987 4188776 1863994..1864389 1 NC_008253.1 hypothetical protein 1864389 4188776 ECP_1813 Escherichia coli 536 hypothetical protein YP_669717.1 1863994 D 362663 CDS YP_669718.1 110641988 4188777 1864430..1865173 1 NC_008253.1 protein YecO 1865173 4188777 ECP_1814 Escherichia coli 536 protein YecO YP_669718.1 1864430 D 362663 CDS YP_669719.1 110641989 4188778 1865170..1866141 1 NC_008253.1 hypothetical protein 1866141 4188778 ECP_1815 Escherichia coli 536 hypothetical protein YP_669719.1 1865170 D 362663 CDS YP_669720.1 110641990 4188781 complement(1868760..1869860) 1 NC_008253.1 cytochrome c-type protein TorY 1869860 4188781 ECP_1818 Escherichia coli 536 cytochrome c-type protein TorY YP_669720.1 1868760 R 362663 CDS YP_669721.1 110641991 4188782 complement(1870248..1870994) 1 NC_008253.1 copper homeostasis protein CutC 1870994 4188782 ECP_1819 Escherichia coli 536 copper homeostasis protein CutC YP_669721.1 1870248 R 362663 CDS YP_669722.1 110641992 4188783 complement(1871008..1871574) 1 NC_008253.1 hypothetical protein 1871574 4188783 ECP_1820 Escherichia coli 536 hypothetical protein YP_669722.1 1871008 R 362663 CDS YP_669723.1 110641993 4188784 complement(1871577..1871756) 1 NC_008253.1 hypothetical protein 1871756 4188784 ECP_1821 Escherichia coli 536 hypothetical protein YP_669723.1 1871577 R 362663 CDS YP_669724.1 110641994 4188785 1871790..1873523 1 NC_008253.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1873523 argS 4188785 argS Escherichia coli 536 arginyl-tRNA synthetase YP_669724.1 1871790 D 362663 CDS YP_669725.1 110641995 4188786 complement(1873576..1873968) 1 NC_008253.1 flagellar protein FlhE 1873968 4188786 ECP_1823 Escherichia coli 536 flagellar protein FlhE YP_669725.1 1873576 R 362663 CDS YP_669726.1 110641996 4188787 complement(1873968..1876046) 1 NC_008253.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1876046 flhA 4188787 flhA Escherichia coli 536 flagellar biosynthesis protein FlhA YP_669726.1 1873968 R 362663 CDS YP_669727.1 110641997 4188788 complement(1876039..1877187) 1 NC_008253.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1877187 flhB 4188788 flhB Escherichia coli 536 flagellar biosynthesis protein FlhB YP_669727.1 1876039 R 362663 CDS YP_669728.1 110641998 4189528 complement(1877396..1878040) 1 NC_008253.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1878040 4189528 ECP_1826 Escherichia coli 536 chemotaxis regulator CheZ YP_669728.1 1877396 R 362663 CDS YP_669729.1 110641999 4189529 complement(1878051..1878440) 1 NC_008253.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1878440 4189529 ECP_1827 Escherichia coli 536 chemotaxis regulatory protein CheY YP_669729.1 1878051 R 362663 CDS YP_669730.1 110642000 4189530 complement(1878455..1879504) 1 NC_008253.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1879504 4189530 ECP_1828 Escherichia coli 536 chemotaxis-specific methylesterase YP_669730.1 1878455 R 362663 CDS YP_669731.1 110642001 4189531 complement(1879507..1880367) 1 NC_008253.1 methylates the MCP; chemotaxis methyltransferase CheR 1880367 4189531 ECP_1829 Escherichia coli 536 chemotaxis methyltransferase CheR YP_669731.1 1879507 R 362663 CDS YP_669732.1 110642002 4189532 complement(1880658..1882319) 1 NC_008253.1 methyl-accepting chemotaxis protein II 1882319 4189532 ECP_1830 Escherichia coli 536 methyl-accepting chemotaxis protein II YP_669732.1 1880658 R 362663 CDS YP_669733.1 110642003 4189533 complement(1882464..1882967) 1 NC_008253.1 purine-binding chemotaxis protein 1882967 4189533 ECP_1831 Escherichia coli 536 purine-binding chemotaxis protein YP_669733.1 1882464 R 362663 CDS YP_669734.1 110642004 4189534 complement(1882988..1884946) 1 NC_008253.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1884946 4189534 ECP_1832 Escherichia coli 536 chemotaxis protein CheA YP_669734.1 1882988 R 362663 CDS YP_669735.1 110642005 4189535 complement(1884957..1885883) 1 NC_008253.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1885883 motB 4189535 motB Escherichia coli 536 flagellar motor protein MotB YP_669735.1 1884957 R 362663 CDS YP_669736.1 110642006 4189536 complement(1885880..1886767) 1 NC_008253.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1886767 4189536 ECP_1834 Escherichia coli 536 flagellar motor protein MotA YP_669736.1 1885880 R 362663 CDS YP_669737.1 110642007 4189537 complement(1886894..1887472) 1 NC_008253.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1887472 4189537 ECP_1835 Escherichia coli 536 transcriptional activator FlhC YP_669737.1 1886894 R 362663 CDS YP_669738.1 110642008 4189538 complement(1887475..1887825) 1 NC_008253.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1887825 4189538 ECP_1836 Escherichia coli 536 transcriptional activator FlhD YP_669738.1 1887475 R 362663 CDS YP_669739.1 110642009 4189539 1888605..1889033 1 NC_008253.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1889033 4189539 ECP_1837 Escherichia coli 536 universal stress protein UspC YP_669739.1 1888605 D 362663 CDS YP_669740.1 110642010 4189540 complement(1889040..1890464) 1 NC_008253.1 trehalose-6-phosphate synthase 1890464 4189540 ECP_1838 Escherichia coli 536 trehalose-6-phosphate synthase YP_669740.1 1889040 R 362663 CDS YP_669741.1 110642011 4189541 complement(1890439..1891296) 1 NC_008253.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1891296 4189541 ECP_1839 Escherichia coli 536 trehalose-6-phosphate phosphatase YP_669741.1 1890439 R 362663 CDS YP_669742.1 110642012 4189542 complement(1891406..1892392) 1 NC_008253.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1892392 araH 4189542 araH Escherichia coli 536 L-arabinose transporter permease YP_669742.1 1891406 R 362663 CDS YP_669743.1 110642013 4189543 complement(1892407..1893921) 1 NC_008253.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1893921 araG 4189543 araG Escherichia coli 536 L-arabinose transporter ATP-binding protein YP_669743.1 1892407 R 362663 CDS YP_669744.1 110642014 4189544 complement(1893991..1894980) 1 NC_008253.1 L-arabinose-binding periplasmic protein 1894980 4189544 ECP_1842 Escherichia coli 536 L-arabinose-binding periplasmic protein YP_669744.1 1893991 R 362663 CDS YP_669745.1 110642015 4189545 complement(1895066..1895305) 1 NC_008253.1 hypothetical protein 1895305 4189545 ECP_1843 Escherichia coli 536 hypothetical protein YP_669745.1 1895066 R 362663 CDS YP_669746.1 110642016 4189546 1895777..1896280 1 NC_008253.1 ferritin 1896280 4189546 ECP_1844 Escherichia coli 536 ferritin YP_669746.1 1895777 D 362663 CDS YP_669747.1 110642017 4189547 complement(1896359..1896610) 1 NC_008253.1 hypothetical protein 1896610 4189547 ECP_1845 Escherichia coli 536 hypothetical protein YP_669747.1 1896359 R 362663 CDS YP_669748.1 110642018 4191112 1896722..1896868 1 NC_008253.1 hypothetical protein 1896868 4191112 ECP_1846 Escherichia coli 536 hypothetical protein YP_669748.1 1896722 D 362663 CDS YP_669749.1 110642019 4191113 1897074..1897397 1 NC_008253.1 hypothetical protein 1897397 4191113 ECP_1847 Escherichia coli 536 hypothetical protein YP_669749.1 1897074 D 362663 CDS YP_669750.1 110642020 4191114 1897569..1898066 1 NC_008253.1 cytoplasmic iron storage protein; ferritin 1898066 4191114 ECP_1848 Escherichia coli 536 ferritin YP_669750.1 1897569 D 362663 CDS YP_669751.1 110642021 4191115 complement(1898104..1898343) 1 NC_008253.1 hypothetical protein 1898343 4191115 ECP_1849 Escherichia coli 536 hypothetical protein YP_669751.1 1898104 R 362663 CDS YP_669752.1 110642022 4191116 1898534..1899745 1 NC_008253.1 tyrosine-specific transport protein 1899745 4191116 ECP_1850 Escherichia coli 536 tyrosine-specific transport protein YP_669752.1 1898534 D 362663 CDS YP_669753.1 110642023 4191117 complement(1899807..1900472) 1 NC_008253.1 metal-binding protein related to the C-terminal domain of SecA; hypothetical protein 1900472 4191117 ECP_1851 Escherichia coli 536 hypothetical protein YP_669753.1 1899807 R 362663 CDS YP_669754.1 110642024 4191118 complement(1901121..1901669) 1 NC_008253.1 phosphatidylglycerophosphate synthetase 1901669 4191118 ECP_1852 Escherichia coli 536 phosphatidylglycerophosphate synthetase YP_669754.1 1901121 R 362663 CDS YP_669755.1 110642025 4191119 complement(1901726..1903051) 1 NC_008253.1 UvrABC system protein C; UvrC excinuclease ABC subunit C 1903051 4191119 ECP_1853 Escherichia coli 536 UvrC excinuclease ABC subunit C YP_669755.1 1901726 R 362663 CDS YP_669756.1 110642026 4191120 complement(1903139..1903690) 1 NC_008253.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1903690 4191120 ECP_1854 Escherichia coli 536 flagella biosynthesis protein FliZ YP_669756.1 1903139 R 362663 CDS YP_669757.1 110642027 4191121 complement(1903736..1904455) 1 NC_008253.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1904455 fliA 4191121 fliA Escherichia coli 536 flagellar biosynthesis sigma factor YP_669757.1 1903736 R 362663 CDS YP_669758.1 110642028 4191122 complement(1904526..1904732) 1 NC_008253.1 hypothetical protein 1904732 4191122 ECP_1856 Escherichia coli 536 hypothetical protein YP_669758.1 1904526 R 362663 CDS YP_669759.1 110642029 4191123 complement(1904774..1906441) 1 NC_008253.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 1906441 4191123 ECP_1857 Escherichia coli 536 flagellin YP_669759.1 1904774 R 362663 CDS YP_669760.1 110642030 4191124 1906707..1908113 1 NC_008253.1 involved in flagellin assembly; flagellar capping protein 1908113 fliD 4191124 fliD Escherichia coli 536 flagellar capping protein YP_669760.1 1906707 D 362663 CDS YP_669761.1 110642031 4191125 1908138..1908548 1 NC_008253.1 flagellin specific chaperone; flagellar protein FliS 1908548 fliS 4191125 fliS Escherichia coli 536 flagellar protein FliS YP_669761.1 1908138 D 362663 CDS YP_669762.1 110642032 4191126 1908548..1908913 1 NC_008253.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1908913 4191126 ECP_1860 Escherichia coli 536 flagellar biosynthesis protein FliT YP_669762.1 1908548 D 362663 CDS YP_669763.1 110642033 4191127 1908991..1910478 1 NC_008253.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1910478 4191127 ECP_1861 Escherichia coli 536 alpha-amylase YP_669763.1 1908991 D 362663 CDS YP_669764.1 110642034 4191128 complement(1910512..1910925) 1 NC_008253.1 hypothetical protein 1910925 4191128 ECP_1862 Escherichia coli 536 hypothetical protein YP_669764.1 1910512 R 362663 CDS YP_669765.1 110642035 4191129 1911112..1912317 1 NC_008253.1 inner membrane protein 1912317 4191129 ECP_1863 Escherichia coli 536 inner membrane protein YP_669765.1 1911112 D 362663 CDS YP_669766.1 110642036 4191130 1912314..1912547 1 NC_008253.1 hypothetical protein 1912547 4191130 ECP_1864 Escherichia coli 536 hypothetical protein YP_669766.1 1912314 D 362663 CDS YP_669767.1 110642037 4190368 1912656..1913324 1 NC_008253.1 hypothetical protein 1913324 4190368 ECP_1865 Escherichia coli 536 hypothetical protein YP_669767.1 1912656 D 362663 CDS YP_669768.1 110642038 4190369 1913321..1913506 1 NC_008253.1 hypothetical protein 1913506 4190369 ECP_1866 Escherichia coli 536 hypothetical protein YP_669768.1 1913321 D 362663 CDS YP_669769.1 110642039 4190370 1913838..1914920 1 NC_008253.1 outer membrane porin protein LC 1914920 4190370 ECP_1867 Escherichia coli 536 outer membrane porin protein LC YP_669769.1 1913838 D 362663 CDS YP_669770.1 110642040 4190371 complement(1915422..1916174) 1 NC_008253.1 transcriptional regulator YbcM 1916174 4190371 ECP_1868 Escherichia coli 536 transcriptional regulator YbcM YP_669770.1 1915422 R 362663 CDS YP_669771.1 110642041 4190372 complement(1916229..1916780) 1 NC_008253.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor 1916780 4190372 ECP_1869 Escherichia coli 536 kinase inhibitor YP_669771.1 1916229 R 362663 CDS YP_669772.1 110642042 4190373 complement(1916949..1917446) 1 NC_008253.1 ethidium resistance protein; member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 1917446 emrE 4190373 emrE Escherichia coli 536 multidrug efflux protein YP_669772.1 1916949 R 362663 CDS YP_669773.1 110642043 4190374 complement(1917626..1917940) 1 NC_008253.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1917940 fliE 4190374 fliE Escherichia coli 536 flagellar hook-basal body protein FliE YP_669773.1 1917626 R 362663 CDS YP_669774.1 110642044 4190375 1918155..1919813 1 NC_008253.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1919813 fliF 4190375 fliF Escherichia coli 536 flagellar MS-ring protein YP_669774.1 1918155 D 362663 CDS YP_669775.1 110642045 4190376 1919806..1920801 1 NC_008253.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1920801 fliG 4190376 fliG Escherichia coli 536 flagellar motor switch protein G YP_669775.1 1919806 D 362663 CDS YP_669776.1 110642046 4190377 1920794..1921480 1 NC_008253.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1921480 fliH 4190377 fliH Escherichia coli 536 flagellar assembly protein H YP_669776.1 1920794 D 362663 CDS YP_669777.1 110642047 4190378 1921480..1922853 1 NC_008253.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1922853 fliI 4190378 fliI Escherichia coli 536 flagellum-specific ATP synthase YP_669777.1 1921480 D 362663 CDS YP_669778.1 110642048 4190379 1922872..1923315 1 NC_008253.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 1923315 fliJ 4190379 fliJ Escherichia coli 536 flagellar biosynthesis chaperone YP_669778.1 1922872 D 362663 CDS YP_669779.1 110642049 4190380 1923312..1924439 1 NC_008253.1 flagellar hook-length control protein 1924439 4190380 ECP_1877 Escherichia coli 536 flagellar hook-length control protein YP_669779.1 1923312 D 362663 CDS YP_669780.1 110642050 4190381 1924544..1925008 1 NC_008253.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 1925008 fliL 4190381 fliL Escherichia coli 536 flagellar basal body protein FliL YP_669780.1 1924544 D 362663 CDS YP_669781.1 110642051 4190382 1924968..1926017 1 NC_008253.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1926017 fliM 4190382 fliM Escherichia coli 536 flagellar motor switch protein FliM YP_669781.1 1924968 D 362663 CDS YP_669782.1 110642052 4190383 1926014..1926427 1 NC_008253.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1926427 fliN 4190383 fliN Escherichia coli 536 flagellar motor switch protein FliN YP_669782.1 1926014 D 362663 CDS YP_669783.1 110642053 4190384 1926430..1926795 1 NC_008253.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 1926795 4190384 ECP_1881 Escherichia coli 536 flagellar biosynthesis protein FliO YP_669783.1 1926430 D 362663 CDS YP_669784.1 110642054 4190385 1926795..1927532 1 NC_008253.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1927532 fliP 4190385 fliP Escherichia coli 536 flagellar biosynthesis protein FliP YP_669784.1 1926795 D 362663 CDS YP_669785.1 110642055 4190386 1927542..1927811 1 NC_008253.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1927811 fliQ 4190386 fliQ Escherichia coli 536 flagellar biosynthesis protein FliQ YP_669785.1 1927542 D 362663 CDS YP_669786.1 110642056 4190387 1927820..1928605 1 NC_008253.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1928605 fliR 4190387 fliR Escherichia coli 536 flagellar biosynthesis protein FliR YP_669786.1 1927820 D 362663 CDS YP_669787.1 110642057 4187245 1928895..1929518 1 NC_008253.1 colanic acid capsular biosynthesis activation protein A 1929518 4187245 ECP_1885 Escherichia coli 536 colanic acid capsular biosynthesis activation protein A YP_669787.1 1928895 D 362663 CDS YP_669788.1 110642058 4187246 complement(1929562..1929750) 1 NC_008253.1 hypothetical protein 1929750 4187246 ECP_1886 Escherichia coli 536 hypothetical protein YP_669788.1 1929562 R 362663 CDS YP_669789.1 110642059 4187247 1929911..1930141 1 NC_008253.1 hypothetical protein 1930141 4187247 ECP_1887 Escherichia coli 536 hypothetical protein YP_669789.1 1929911 D 362663 CDS YP_669790.1 110642060 4187248 1930437..1931252 1 NC_008253.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1931252 4187248 ECP_1888 Escherichia coli 536 mannosyl-3-phosphoglycerate phosphatase YP_669790.1 1930437 D 362663 CDS YP_669791.1 110642061 4187249 complement(1931249..1932943) 1 NC_008253.1 hypothetical protein 1932943 4187249 ECP_1889 Escherichia coli 536 hypothetical protein YP_669791.1 1931249 R 362663 CDS YP_669792.1 110642062 4187250 complement(1933114..1933296) 1 NC_008253.1 hypothetical protein 1933296 4187250 ECP_1890 Escherichia coli 536 hypothetical protein YP_669792.1 1933114 R 362663 CDS YP_669793.1 110642063 4187251 complement(1933375..1934292) 1 NC_008253.1 hypothetical protein 1934292 4187251 ECP_1891 Escherichia coli 536 hypothetical protein YP_669793.1 1933375 R 362663 CDS YP_669794.1 110642064 4187252 1934465..1935385 1 NC_008253.1 hypothetical protein 1935385 4187252 ECP_1892 Escherichia coli 536 hypothetical protein YP_669794.1 1934465 D 362663 CDS YP_669795.1 110642065 4187253 complement(1935374..1935844) 1 NC_008253.1 very short patch repair protein 1935844 4187253 ECP_1893 Escherichia coli 536 very short patch repair protein YP_669795.1 1935374 R 362663 CDS YP_669796.1 110642066 4187254 complement(1935825..1937243) 1 NC_008253.1 DNA cytosine methylase 1937243 4187254 ECP_1894 Escherichia coli 536 DNA cytosine methylase YP_669796.1 1935825 R 362663 CDS YP_669797.1 110642067 4187255 complement(1937310..1938005) 1 NC_008253.1 hypothetical protein 1938005 4187255 ECP_1895 Escherichia coli 536 hypothetical protein YP_669797.1 1937310 R 362663 CDS YP_669798.1 110642068 4187256 complement(1938045..1938347) 1 NC_008253.1 hypothetical protein 1938347 4187256 ECP_1896 Escherichia coli 536 hypothetical protein YP_669798.1 1938045 R 362663 CDS YP_669799.1 110642069 4187257 1938503..1938688 1 NC_008253.1 hypothetical protein 1938688 4187257 ECP_1897 Escherichia coli 536 hypothetical protein YP_669799.1 1938503 D 362663 CDS YP_669800.1 110642070 4187258 1938975..1940033 1 NC_008253.1 outer membrane pore protein 1940033 4187258 ECP_1898 Escherichia coli 536 outer membrane pore protein YP_669800.1 1938975 D 362663 CDS YP_669801.1 110642071 4187259 1940115..1940249 1 NC_008253.1 hypothetical protein 1940249 4187259 ECP_1899 Escherichia coli 536 hypothetical protein YP_669801.1 1940115 D 362663 CDS YP_669802.1 110642072 4187260 1940629..1941480 1 NC_008253.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1941480 4187260 ECP_1900 Escherichia coli 536 chaperone protein HchA YP_669802.1 1940629 D 362663 CDS YP_669803.1 110642073 4187261 complement(1941588..1942946) 1 NC_008253.1 sensor-like histidine kinase YedV 1942946 4187261 ECP_1901 Escherichia coli 536 sensor-like histidine kinase YedV YP_669803.1 1941588 R 362663 CDS YP_669804.1 110642074 4187262 complement(1942946..1943728) 1 NC_008253.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 1943728 4187262 ECP_1902 Escherichia coli 536 transcriptional regulatory protein YedW YP_669804.1 1942946 R 362663 CDS YP_669805.1 110642075 4187263 1943750..1944163 1 NC_008253.1 transthyretin-like protein 1944163 4187263 ECP_1903 Escherichia coli 536 transthyretin-like protein YP_669805.1 1943750 D 362663 CDS YP_669806.1 110642076 4188224 1944272..1944505 1 NC_008253.1 hypothetical protein 1944505 4188224 ECP_1904 Escherichia coli 536 hypothetical protein YP_669806.1 1944272 D 362663 CDS YP_669807.1 110642077 4188225 1944640..1945275 1 NC_008253.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 1945275 4188225 ECP_1905 Escherichia coli 536 sulfite oxidase subunit YedY YP_669807.1 1944640 D 362663 CDS YP_669808.1 110642078 4188226 1945276..1945911 1 NC_008253.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 1945911 4188226 ECP_1906 Escherichia coli 536 sulfite oxidase subunit YedZ YP_669808.1 1945276 D 362663 CDS YP_669809.1 110642079 4188227 1946169..1946819 1 NC_008253.1 hypothetical protein 1946819 4188227 ECP_1907 Escherichia coli 536 hypothetical protein YP_669809.1 1946169 D 362663 CDS YP_669810.1 110642080 4188228 1946855..1947184 1 NC_008253.1 hypothetical protein 1947184 4188228 ECP_1908 Escherichia coli 536 hypothetical protein YP_669810.1 1946855 D 362663 CDS YP_669811.1 110642081 4188229 1947667..1948887 1 NC_008253.1 phage-related integrase 1948887 4188229 ECP_1909 Escherichia coli 536 phage-related integrase YP_669811.1 1947667 D 362663 CDS YP_669812.1 110642082 4188230 1949001..1950821 1 NC_008253.1 hypothetical protein 1950821 4188230 ECP_1910 Escherichia coli 536 hypothetical protein YP_669812.1 1949001 D 362663 CDS YP_669813.1 110642083 4188231 complement(1950936..1952399) 1 NC_008253.1 PilV-like protein 1952399 4188231 ECP_1911 Escherichia coli 536 PilV-like protein YP_669813.1 1950936 R 362663 CDS YP_669814.1 110642084 4188232 complement(1952452..1953009) 1 NC_008253.1 type IV pilin protein 1953009 4188232 ECP_1912 Escherichia coli 536 type IV pilin protein YP_669814.1 1952452 R 362663 CDS YP_669815.1 110642085 4188233 complement(1953408..1953713) 1 NC_008253.1 hypothetical protein 1953713 4188233 ECP_1913 Escherichia coli 536 hypothetical protein YP_669815.1 1953408 R 362663 CDS YP_669816.1 110642086 4188234 1954359..1955861 1 NC_008253.1 hypothetical protein 1955861 4188234 ECP_1914 Escherichia coli 536 hypothetical protein YP_669816.1 1954359 D 362663 CDS YP_669817.1 110642087 4188235 1955978..1956841 1 NC_008253.1 hypothetical protein 1956841 4188235 ECP_1915 Escherichia coli 536 hypothetical protein YP_669817.1 1955978 D 362663 CDS YP_669818.1 110642088 4188236 1957136..1957369 1 NC_008253.1 hypothetical protein 1957369 4188236 ECP_1916 Escherichia coli 536 hypothetical protein YP_669818.1 1957136 D 362663 CDS YP_669819.1 110642089 4188237 1957619..1958455 1 NC_008253.1 hypothetical protein 1958455 4188237 ECP_1917 Escherichia coli 536 hypothetical protein YP_669819.1 1957619 D 362663 CDS YP_669820.1 110642090 4188238 complement(1958515..1958790) 1 NC_008253.1 hypothetical protein 1958790 4188238 ECP_1918 Escherichia coli 536 hypothetical protein YP_669820.1 1958515 R 362663 CDS YP_669821.1 110642091 4188239 complement(1958801..1959331) 1 NC_008253.1 hypothetical protein 1959331 4188239 ECP_1919 Escherichia coli 536 hypothetical protein YP_669821.1 1958801 R 362663 CDS YP_669822.1 110642092 4188240 1959764..1960237 1 NC_008253.1 hypothetical protein 1960237 4188240 ECP_1920 Escherichia coli 536 hypothetical protein YP_669822.1 1959764 D 362663 CDS YP_669823.1 110642093 4188241 1960269..1960439 1 NC_008253.1 hypothetical protein 1960439 4188241 ECP_1921 Escherichia coli 536 hypothetical protein YP_669823.1 1960269 D 362663 CDS YP_669824.1 110642094 4188242 complement(1960727..1961899) 1 NC_008253.1 hypothetical protein 1961899 4188242 ECP_1922 Escherichia coli 536 hypothetical protein YP_669824.1 1960727 R 362663 CDS YP_669825.1 110642095 4188243 complement(1961960..1962922) 1 NC_008253.1 hypothetical protein 1962922 4188243 ECP_1923 Escherichia coli 536 hypothetical protein YP_669825.1 1961960 R 362663 CDS YP_669826.1 110642096 4187452 1964276..1964857 1 NC_008253.1 hypothetical protein 1964857 4187452 ECP_1924 Escherichia coli 536 hypothetical protein YP_669826.1 1964276 D 362663 CDS YP_669827.1 110642097 4187453 complement(1964942..1965673) 1 NC_008253.1 hypothetical protein 1965673 4187453 ECP_1925 Escherichia coli 536 hypothetical protein YP_669827.1 1964942 R 362663 CDS YP_669828.1 110642098 4187454 1965847..1966326 1 NC_008253.1 hypothetical protein 1966326 4187454 ECP_1926 Escherichia coli 536 hypothetical protein YP_669828.1 1965847 D 362663 CDS YP_669829.1 110642099 4187455 1966487..1966891 1 NC_008253.1 DNA-binding protein 1966891 4187455 ECP_1927 Escherichia coli 536 DNA-binding protein YP_669829.1 1966487 D 362663 CDS YP_669830.1 110642100 4187456 complement(1966955..1967305) 1 NC_008253.1 hypothetical protein 1967305 4187456 ECP_1928 Escherichia coli 536 hypothetical protein YP_669830.1 1966955 R 362663 CDS YP_669831.1 110642101 4187457 complement(1967414..1967656) 1 NC_008253.1 hypothetical protein 1967656 4187457 ECP_1929 Escherichia coli 536 hypothetical protein YP_669831.1 1967414 R 362663 CDS YP_669832.1 110642102 4187458 complement(1967729..1968025) 1 NC_008253.1 hypothetical protein 1968025 4187458 ECP_1930 Escherichia coli 536 hypothetical protein YP_669832.1 1967729 R 362663 CDS YP_669833.1 110642103 4187459 complement(1968078..1968368) 1 NC_008253.1 hypothetical protein 1968368 4187459 ECP_1931 Escherichia coli 536 hypothetical protein YP_669833.1 1968078 R 362663 CDS YP_669834.1 110642104 4187460 complement(1968450..1968668) 1 NC_008253.1 regulatory protein 1968668 4187460 ECP_1932 Escherichia coli 536 regulatory protein YP_669834.1 1968450 R 362663 CDS YP_669835.1 110642105 4187461 complement(1968885..1969721) 1 NC_008253.1 hypothetical protein 1969721 4187461 ECP_1933 Escherichia coli 536 hypothetical protein YP_669835.1 1968885 R 362663 CDS YP_669836.1 110642106 4187462 1970183..1970980 1 NC_008253.1 hypothetical protein 1970980 4187462 ECP_1934 Escherichia coli 536 hypothetical protein YP_669836.1 1970183 D 362663 CDS YP_669837.1 110642107 4187464 1971537..1972580 1 NC_008253.1 P4-like integrase 1972580 4187464 ECP_1936 Escherichia coli 536 P4-like integrase YP_669837.1 1971537 D 362663 CDS YP_669838.1 110642108 4187465 complement(1972774..1974078) 1 NC_008253.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 1974078 4187465 ECP_1937 Escherichia coli 536 salicylate synthase Irp9 YP_669838.1 1972774 R 362663 CDS YP_669839.1 110642109 4187466 complement(1974106..1975494) 1 NC_008253.1 YbtX; cytoplasmic transmembrane protein 1975494 4187466 ECP_1938 Escherichia coli 536 cytoplasmic transmembrane protein YP_669839.1 1974106 R 362663 CDS YP_669840.1 110642110 4187467 complement(1975379..1977181) 1 NC_008253.1 ABC transporter permease 1977181 4187467 ECP_1939 Escherichia coli 536 ABC transporter permease YP_669840.1 1975379 R 362663 CDS YP_669841.1 110642111 4187468 complement(1977168..1978880) 1 NC_008253.1 inner membrane ABC-transporter (YbtP) 1978880 4187468 ECP_1940 Escherichia coli 536 inner membrane ABC-transporter (YbtP) YP_669841.1 1977168 R 362663 CDS YP_669842.1 110642112 4187469 1979137..1980096 1 NC_008253.1 yersiniabactin transcriptional regulator, YbtA 1980096 4187469 ECP_1941 Escherichia coli 536 yersiniabactin transcriptional regulator, YbtA YP_669842.1 1979137 D 362663 CDS YP_669843.1 110642113 4191228 1980287..1986394 1 NC_008253.1 HMWP2 nonribosomal peptidesynthetase; yersiniabactin biosynthetic protein 1986394 4191228 ECP_1942 Escherichia coli 536 yersiniabactin biosynthetic protein YP_669843.1 1980287 D 362663 CDS YP_669844.1 110642114 4191229 1986482..1995973 1 NC_008253.1 HMWP1nonribosomal peptide/polyketide synthase; yersiniabactin biosynthetic protein 1995973 4191229 ECP_1943 Escherichia coli 536 yersiniabactin biosynthetic protein YP_669844.1 1986482 D 362663 CDS YP_669845.1 110642115 4191230 1995970..1997070 1 NC_008253.1 yersiniabactin biosynthetic protein YbtU 1997070 4191230 ECP_1944 Escherichia coli 536 yersiniabactin biosynthetic protein YbtU YP_669845.1 1995970 D 362663 CDS YP_669846.1 110642116 4191231 1997082..1997870 1 NC_008253.1 yersiniabactin biosynthetic protein YbtT 1997870 4191231 ECP_1945 Escherichia coli 536 yersiniabactin biosynthetic protein YbtT YP_669846.1 1997082 D 362663 CDS YP_669847.1 110642117 4191232 1997874..1999451 1 NC_008253.1 yersiniabactin siderophore biosynthetic protein YbtE 1999451 4191232 ECP_1946 Escherichia coli 536 yersiniabactin siderophore biosynthetic protein YbtE YP_669847.1 1997874 D 362663 CDS YP_669848.1 110642118 4191233 1999582..2001603 1 NC_008253.1 pesticin receptor 2001603 4191233 ECP_1947 Escherichia coli 536 pesticin receptor YP_669848.1 1999582 D 362663 CDS YP_669849.1 110642119 4191234 2002251..2003000 1 NC_008253.1 hypothetical protein 2003000 4191234 ECP_1948 Escherichia coli 536 hypothetical protein YP_669849.1 2002251 D 362663 CDS YP_669850.1 110642120 4191235 2002927..2003097 1 NC_008253.1 hypothetical protein 2003097 4191235 ECP_1949 Escherichia coli 536 hypothetical protein YP_669850.1 2002927 D 362663 CDS YP_669851.1 110642121 4191236 2003133..2004602 1 NC_008253.1 hypothetical protein 2004602 4191236 ECP_1950 Escherichia coli 536 hypothetical protein YP_669851.1 2003133 D 362663 CDS YP_669852.1 110642122 4191237 2004615..2005091 1 NC_008253.1 hypothetical protein 2005091 4191237 ECP_1951 Escherichia coli 536 hypothetical protein YP_669852.1 2004615 D 362663 CDS YP_669853.1 110642123 4191238 complement(2005219..2006271) 1 NC_008253.1 hypothetical protein 2006271 4191238 ECP_1952 Escherichia coli 536 hypothetical protein YP_669853.1 2005219 R 362663 CDS YP_669854.1 110642124 4191239 2006300..2006458 1 NC_008253.1 hypothetical protein 2006458 4191239 ECP_1953 Escherichia coli 536 hypothetical protein YP_669854.1 2006300 D 362663 CDS YP_669855.1 110642125 4191240 2006586..2007902 1 NC_008253.1 shikimate transporter 2007902 4191240 ECP_1954 Escherichia coli 536 shikimate transporter YP_669855.1 2006586 D 362663 CDS YP_669856.1 110642126 4191241 2008004..2009458 1 NC_008253.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2009458 4191241 ECP_1955 Escherichia coli 536 AMP nucleosidase YP_669856.1 2008004 D 362663 CDS YP_669857.1 110642127 4191242 2009801..2010517 1 NC_008253.1 hypothetical protein 2010517 4191242 ECP_1956 Escherichia coli 536 hypothetical protein YP_669857.1 2009801 D 362663 CDS YP_669858.1 110642128 4191243 complement(2010573..2010860) 1 NC_008253.1 hypothetical protein 2010860 4191243 ECP_1957 Escherichia coli 536 hypothetical protein YP_669858.1 2010573 R 362663 CDS YP_669859.1 110642129 4191244 2011373..2012290 1 NC_008253.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2012290 4191244 ECP_1958 Escherichia coli 536 nitrogen assimilation transcriptional regulator YP_669859.1 2011373 D 362663 CDS YP_669860.1 110642130 4191245 2012392..2013342 1 NC_008253.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2013342 cbl 4191245 cbl Escherichia coli 536 transcriptional regulator Cbl YP_669860.1 2012392 D 362663 CDS YP_669861.1 110642131 4191246 2013616..2015103 1 NC_008253.1 hypothetical protein 2015103 4191246 ECP_1960 Escherichia coli 536 hypothetical protein YP_669861.1 2013616 D 362663 CDS YP_669862.1 110642132 4191574 2015441..2016712 1 NC_008253.1 bacteriophage integrase 2016712 4191574 ECP_1962 Escherichia coli 536 bacteriophage integrase YP_669862.1 2015441 D 362663 CDS YP_669863.1 110642133 4191575 complement(2016992..2017504) 1 NC_008253.1 hypothetical protein 2017504 4191575 ECP_1963 Escherichia coli 536 hypothetical protein YP_669863.1 2016992 R 362663 CDS YP_669864.1 110642134 4191576 complement(2017539..2018261) 1 NC_008253.1 thioesterase 2018261 4191576 ECP_1964 Escherichia coli 536 thioesterase YP_669864.1 2017539 R 362663 CDS YP_669865.1 110642135 4191577 complement(2018254..2019768) 1 NC_008253.1 hypothetical protein 2019768 4191577 ECP_1965 Escherichia coli 536 hypothetical protein YP_669865.1 2018254 R 362663 CDS YP_669866.1 110642136 4191578 complement(2019781..2022240) 1 NC_008253.1 polyketide synthase 2022240 4191578 ECP_1966 Escherichia coli 536 polyketide synthase YP_669866.1 2019781 R 362663 CDS YP_669867.1 110642137 4191579 complement(2022271..2026638) 1 NC_008253.1 non-ribosomal peptide synthetase 2026638 4191579 ECP_1967 Escherichia coli 536 non-ribosomal peptide synthetase YP_669867.1 2022271 R 362663 CDS YP_669868.1 110642138 4191580 complement(2026635..2028074) 1 NC_008253.1 drug/sodium antiporter 2028074 4191580 ECP_1968 Escherichia coli 536 drug/sodium antiporter YP_669868.1 2026635 R 362663 CDS YP_669869.1 110642139 4191581 complement(2028136..2029599) 1 NC_008253.1 amidase 2029599 4191581 ECP_1969 Escherichia coli 536 amidase YP_669869.1 2028136 R 362663 CDS YP_669870.1 110642140 4191582 complement(2029592..2036056) 1 NC_008253.1 non-ribosomal peptide synthase 2036056 4191582 ECP_1970 Escherichia coli 536 non-ribosomal peptide synthase YP_669870.1 2029592 R 362663 CDS YP_669871.1 110642141 4191583 complement(2036067..2042567) 1 NC_008253.1 non-ribosomal peptide synthase 2042567 4191583 ECP_1971 Escherichia coli 536 non-ribosomal peptide synthase YP_669871.1 2036067 R 362663 CDS YP_669872.1 110642142 4191584 complement(2042611..2045643) 1 NC_008253.1 polyketide synthase 2045643 4191584 ECP_1972 Escherichia coli 536 polyketide synthase YP_669872.1 2042611 R 362663 CDS YP_669873.1 110642143 4191585 complement(2045693..2050489) 1 NC_008253.1 peptide synthetase 2050489 4191585 ECP_1973 Escherichia coli 536 peptide synthetase YP_669873.1 2045693 R 362663 CDS YP_669874.1 110642144 4191586 complement(2050537..2051805) 1 NC_008253.1 malonyl-CoA transacylase 2051805 4191586 ECP_1974 Escherichia coli 536 malonyl-CoA transacylase YP_669874.1 2050537 R 362663 CDS YP_669875.1 110642145 4191587 complement(2051802..2052932) 1 NC_008253.1 acyl-CoA dehydrogenase 2052932 4191587 ECP_1975 Escherichia coli 536 acyl-CoA dehydrogenase YP_669875.1 2051802 R 362663 CDS YP_669876.1 110642146 4191588 complement(2052936..2053184) 1 NC_008253.1 D-alanyl carrier protein 2053184 4191588 ECP_1976 Escherichia coli 536 D-alanyl carrier protein YP_669876.1 2052936 R 362663 CDS YP_669877.1 110642147 4191589 complement(2053214..2054083) 1 NC_008253.1 3-hydroxybutyryl-CoA dehydrogenase 2054083 4191589 ECP_1977 Escherichia coli 536 3-hydroxybutyryl-CoA dehydrogenase YP_669877.1 2053214 R 362663 CDS YP_669878.1 110642148 4191590 complement(2054093..2056693) 1 NC_008253.1 polyketide synthase 2056693 4191590 ECP_1978 Escherichia coli 536 polyketide synthase YP_669878.1 2054093 R 362663 CDS YP_669879.1 110642149 4191591 complement(2056734..2066354) 1 NC_008253.1 polyketide synthase 2066354 4191591 ECP_1979 Escherichia coli 536 polyketide synthase YP_669879.1 2056734 R 362663 CDS YP_669880.1 110642150 4188002 2066393..2066581 1 NC_008253.1 hypothetical protein 2066581 4188002 ECP_1980 Escherichia coli 536 hypothetical protein YP_669880.1 2066393 D 362663 CDS YP_669881.1 110642151 4188003 2066788..2067000 1 NC_008253.1 transcriptional regulator 2067000 4188003 ECP_1981 Escherichia coli 536 transcriptional regulator YP_669881.1 2066788 D 362663 CDS YP_669882.1 110642152 4188004 2067001..2067735 1 NC_008253.1 4'-phosphopantetheinyl transferase 2067735 4188004 ECP_1982 Escherichia coli 536 4'-phosphopantetheinyl transferase YP_669882.1 2067001 D 362663 CDS YP_669883.1 110642153 4188005 2067881..2068147 1 NC_008253.1 IS1400 transposase A 2068147 4188005 ECP_1983 Escherichia coli 536 IS1400 transposase A YP_669883.1 2067881 D 362663 CDS YP_669884.1 110642154 4188006 2068252..2068731 1 NC_008253.1 IS1400 transposase B 2068731 4188006 ECP_1984 Escherichia coli 536 IS1400 transposase B YP_669884.1 2068252 D 362663 CDS YP_669885.1 110642155 4188007 2068722..2068949 1 NC_008253.1 transposase 2068949 4188007 ECP_1985 Escherichia coli 536 transposase YP_669885.1 2068722 D 362663 CDS YP_669886.1 110642156 4188008 complement(2069039..2069452) 1 NC_008253.1 hypothetical protein 2069452 4188008 ECP_1986 Escherichia coli 536 hypothetical protein YP_669886.1 2069039 R 362663 CDS YP_669887.1 110642157 4188009 complement(2069480..2069707) 1 NC_008253.1 hypothetical protein 2069707 4188009 ECP_1987 Escherichia coli 536 hypothetical protein YP_669887.1 2069480 R 362663 CDS YP_669888.1 110642158 4188010 complement(2069756..2070691) 1 NC_008253.1 hypothetical protein 2070691 4188010 ECP_1988 Escherichia coli 536 hypothetical protein YP_669888.1 2069756 R 362663 CDS YP_669889.1 110642159 4188011 complement(2070753..2071832) 1 NC_008253.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2071832 cobT 4188011 cobT Escherichia coli 536 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_669889.1 2070753 R 362663 CDS YP_669890.1 110642160 4188012 complement(2071844..2072587) 1 NC_008253.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2072587 cobS 4188012 cobS Escherichia coli 536 cobalamin synthase YP_669890.1 2071844 R 362663 CDS YP_669891.1 110642161 4188013 complement(2072584..2073129) 1 NC_008253.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 2073129 cobU 4188013 cobU Escherichia coli 536 adenosylcobinamide kinase YP_669891.1 2072584 R 362663 CDS YP_669892.1 110642162 4188014 complement(2073594..2073758) 1 NC_008253.1 hypothetical protein 2073758 4188014 ECP_1992 Escherichia coli 536 hypothetical protein YP_669892.1 2073594 R 362663 CDS YP_669893.1 110642163 4188015 2074497..2074694 1 NC_008253.1 hypothetical protein 2074694 4188015 ECP_1993 Escherichia coli 536 hypothetical protein YP_669893.1 2074497 D 362663 CDS YP_669894.1 110642164 4188016 2074801..2076948 1 NC_008253.1 outer membrane receptor for iron compound or colicin 2076948 4188016 ECP_1994 Escherichia coli 536 outer membrane receptor for iron compound or colicin YP_669894.1 2074801 D 362663 CDS YP_669895.1 110642165 4188017 complement(2076923..2077207) 1 NC_008253.1 hypothetical protein 2077207 4188017 ECP_1995 Escherichia coli 536 hypothetical protein YP_669895.1 2076923 R 362663 CDS YP_669896.1 110642166 4188018 complement(2077319..2077963) 1 NC_008253.1 hypothetical protein 2077963 4188018 ECP_1996 Escherichia coli 536 hypothetical protein YP_669896.1 2077319 R 362663 CDS YP_669897.1 110642167 4188019 complement(2077948..2079171) 1 NC_008253.1 phosphoadenosine phosphosulfate reductase 2079171 4188019 ECP_1997 Escherichia coli 536 phosphoadenosine phosphosulfate reductase YP_669897.1 2077948 R 362663 CDS YP_669898.1 110642168 4188020 2080219..2080872 1 NC_008253.1 hypothetical protein 2080872 4188020 ECP_1998 Escherichia coli 536 hypothetical protein YP_669898.1 2080219 D 362663 CDS YP_669899.1 110642169 4188021 2080886..2082082 1 NC_008253.1 hypothetical protein 2082082 4188021 ECP_1999 Escherichia coli 536 hypothetical protein YP_669899.1 2080886 D 362663 CDS YP_669900.1 110642170 4190388 2081949..2082641 1 NC_008253.1 hypothetical protein 2082641 4190388 ECP_2000 Escherichia coli 536 hypothetical protein YP_669900.1 2081949 D 362663 CDS YP_669901.1 110642171 4190389 2082643..2083416 1 NC_008253.1 hypothetical protein 2083416 4190389 ECP_2001 Escherichia coli 536 hypothetical protein YP_669901.1 2082643 D 362663 CDS YP_669902.1 110642172 4190390 2083687..2084166 1 NC_008253.1 hypothetical protein 2084166 4190390 ECP_2002 Escherichia coli 536 hypothetical protein YP_669902.1 2083687 D 362663 CDS YP_669903.1 110642173 4190391 2084106..2084222 1 NC_008253.1 hypothetical protein 2084222 4190391 ECP_2003 Escherichia coli 536 hypothetical protein YP_669903.1 2084106 D 362663 CDS YP_669904.1 110642174 4190392 2084418..2085632 1 NC_008253.1 carbohydrate kinase 2085632 4190392 ECP_2004 Escherichia coli 536 carbohydrate kinase YP_669904.1 2084418 D 362663 CDS YP_669905.1 110642175 4190393 2085646..2086404 1 NC_008253.1 hypothetical protein 2086404 4190393 ECP_2005 Escherichia coli 536 hypothetical protein YP_669905.1 2085646 D 362663 CDS YP_669906.1 110642176 4190394 2086458..2087423 1 NC_008253.1 hypothetical protein 2087423 4190394 ECP_2006 Escherichia coli 536 hypothetical protein YP_669906.1 2086458 D 362663 CDS YP_669907.1 110642177 4190395 2087426..2088460 1 NC_008253.1 phosphotriesterase 2088460 4190395 ECP_2007 Escherichia coli 536 phosphotriesterase YP_669907.1 2087426 D 362663 CDS YP_669908.1 110642178 4190396 complement(2088500..2088613) 1 NC_008253.1 hypothetical protein 2088613 4190396 ECP_2008 Escherichia coli 536 hypothetical protein YP_669908.1 2088500 R 362663 CDS YP_669909.1 110642179 4190397 complement(2088676..2088762) 1 NC_008253.1 hypothetical protein 2088762 4190397 ECP_2009 Escherichia coli 536 hypothetical protein YP_669909.1 2088676 R 362663 CDS YP_669910.1 110642180 4190398 complement(2088872..2089033) 1 NC_008253.1 transposase (part) 2089033 4190398 ECP_2010 Escherichia coli 536 transposase (part) YP_669910.1 2088872 R 362663 CDS YP_669911.1 110642181 4190399 complement(2089112..2089969) 1 NC_008253.1 transposase 2089969 4190399 ECP_2011 Escherichia coli 536 transposase YP_669911.1 2089112 R 362663 CDS YP_669912.1 110642182 4190400 complement(2090228..2090491) 1 NC_008253.1 transposase 2090491 4190400 ECP_2012 Escherichia coli 536 transposase YP_669912.1 2090228 R 362663 CDS YP_669913.1 110642183 4190401 complement(2090775..2091014) 1 NC_008253.1 hypothetical protein 2091014 4190401 ECP_2013 Escherichia coli 536 hypothetical protein YP_669913.1 2090775 R 362663 CDS YP_669914.1 110642184 4190402 complement(2091160..2091561) 1 NC_008253.1 hypothetical protein 2091561 4190402 ECP_2014 Escherichia coli 536 hypothetical protein YP_669914.1 2091160 R 362663 CDS YP_669915.1 110642185 4190403 complement(2091727..2092185) 1 NC_008253.1 hypothetical protein 2092185 4190403 ECP_2015 Escherichia coli 536 hypothetical protein YP_669915.1 2091727 R 362663 CDS YP_669916.1 110642186 4190404 complement(2092100..2092297) 1 NC_008253.1 hypothetical protein 2092297 4190404 ECP_2016 Escherichia coli 536 hypothetical protein YP_669916.1 2092100 R 362663 CDS YP_669917.1 110642187 4190405 2093064..2093444 1 NC_008253.1 hypothetical protein 2093444 4190405 ECP_2017 Escherichia coli 536 hypothetical protein YP_669917.1 2093064 D 362663 CDS YP_669918.1 110642188 4190406 complement(2093412..2093645) 1 NC_008253.1 hypothetical protein 2093645 4190406 ECP_2018 Escherichia coli 536 hypothetical protein YP_669918.1 2093412 R 362663 CDS YP_669919.1 110642189 4190081 2093877..2095073 1 NC_008253.1 transposase 2095073 4190081 ECP_2019 Escherichia coli 536 transposase YP_669919.1 2093877 D 362663 CDS YP_669920.1 110642190 4190082 2095269..2095475 1 NC_008253.1 regulatory protein 2095475 4190082 ECP_2020 Escherichia coli 536 regulatory protein YP_669920.1 2095269 D 362663 CDS YP_669921.1 110642191 4190083 2095569..2096171 1 NC_008253.1 hypothetical protein 2096171 4190083 ECP_2021 Escherichia coli 536 hypothetical protein YP_669921.1 2095569 D 362663 CDS YP_669922.1 110642192 4190084 2096645..2096860 1 NC_008253.1 hypothetical protein 2096860 4190084 ECP_2022 Escherichia coli 536 hypothetical protein YP_669922.1 2096645 D 362663 CDS YP_669923.1 110642193 4190085 complement(2096951..2097181) 1 NC_008253.1 hypothetical protein 2097181 4190085 ECP_2023 Escherichia coli 536 hypothetical protein YP_669923.1 2096951 R 362663 CDS YP_669924.1 110642194 4190086 complement(2097197..2097976) 1 NC_008253.1 transposase/IS protein 2097976 4190086 ECP_2024 Escherichia coli 536 transposase/IS protein YP_669924.1 2097197 R 362663 CDS YP_669925.1 110642195 4190087 complement(2097976..2098998) 1 NC_008253.1 transposase for insertion sequence IS100 2098998 4190087 ECP_2025 Escherichia coli 536 transposase for insertion sequence IS100 YP_669925.1 2097976 R 362663 CDS YP_669926.1 110642196 4190088 complement(2099025..2099267) 1 NC_008253.1 hypothetical protein 2099267 4190088 ECP_2026 Escherichia coli 536 hypothetical protein YP_669926.1 2099025 R 362663 CDS YP_669927.1 110642197 4190089 complement(2099300..2099527) 1 NC_008253.1 hypothetical protein 2099527 4190089 ECP_2027 Escherichia coli 536 hypothetical protein YP_669927.1 2099300 R 362663 CDS YP_669928.1 110642198 4190090 complement(2099549..2099926) 1 NC_008253.1 hypothetical protein 2099926 4190090 ECP_2028 Escherichia coli 536 hypothetical protein YP_669928.1 2099549 R 362663 CDS YP_669929.1 110642199 4190091 2099853..2100113 1 NC_008253.1 hypothetical protein 2100113 4190091 ECP_2029 Escherichia coli 536 hypothetical protein YP_669929.1 2099853 D 362663 CDS YP_669930.1 110642200 4190092 2100495..2101280 1 NC_008253.1 hypothetical protein 2101280 4190092 ECP_2030 Escherichia coli 536 hypothetical protein YP_669930.1 2100495 D 362663 CDS YP_669931.1 110642201 4190093 2101205..2101666 1 NC_008253.1 hypothetical protein 2101666 4190093 ECP_2031 Escherichia coli 536 hypothetical protein YP_669931.1 2101205 D 362663 CDS YP_669932.1 110642202 4190094 2101731..2101967 1 NC_008253.1 hypothetical protein 2101967 4190094 ECP_2032 Escherichia coli 536 hypothetical protein YP_669932.1 2101731 D 362663 CDS YP_669933.1 110642203 4190095 complement(2102508..2103275) 1 NC_008253.1 ABC transporter 2103275 4190095 ECP_2033 Escherichia coli 536 ABC transporter YP_669933.1 2102508 R 362663 CDS YP_669934.1 110642204 4190096 complement(2103272..2104330) 1 NC_008253.1 iron ABC transporter 2104330 4190096 ECP_2034 Escherichia coli 536 iron ABC transporter YP_669934.1 2103272 R 362663 CDS YP_669935.1 110642205 4190097 complement(2104349..2105341) 1 NC_008253.1 iron-chelating periplasmic-binding protein 2105341 4190097 ECP_2035 Escherichia coli 536 iron-chelating periplasmic-binding protein YP_669935.1 2104349 R 362663 CDS YP_669936.1 110642206 4190098 complement(2105349..2107514) 1 NC_008253.1 TonB-dependent receptor 2107514 4190098 ECP_2036 Escherichia coli 536 TonB-dependent receptor YP_669936.1 2105349 R 362663 CDS YP_669937.1 110642207 4190099 2107943..2108377 1 NC_008253.1 hypothetical protein 2108377 4190099 ECP_2037 Escherichia coli 536 hypothetical protein YP_669937.1 2107943 D 362663 CDS YP_669938.1 110642208 4190100 2108595..2110979 1 NC_008253.1 hypothetical protein 2110979 4190100 ECP_2038 Escherichia coli 536 hypothetical protein YP_669938.1 2108595 D 362663 CDS YP_669939.1 110642209 4189792 2110976..2111881 1 NC_008253.1 hypothetical protein 2111881 4189792 ECP_2039 Escherichia coli 536 hypothetical protein YP_669939.1 2110976 D 362663 CDS YP_669940.1 110642210 4189793 2111878..2112948 1 NC_008253.1 hypothetical protein 2112948 4189793 ECP_2040 Escherichia coli 536 hypothetical protein YP_669940.1 2111878 D 362663 CDS YP_669941.1 110642211 4189794 2113084..2113761 1 NC_008253.1 hypothetical protein 2113761 4189794 ECP_2041 Escherichia coli 536 hypothetical protein YP_669941.1 2113084 D 362663 CDS YP_669942.1 110642212 4189795 2113777..2114187 1 NC_008253.1 hypothetical protein 2114187 4189795 ECP_2042 Escherichia coli 536 hypothetical protein YP_669942.1 2113777 D 362663 CDS YP_669943.1 110642213 4189796 2114408..2115229 1 NC_008253.1 hypothetical protein 2115229 4189796 ECP_2043 Escherichia coli 536 hypothetical protein YP_669943.1 2114408 D 362663 CDS YP_669944.1 110642214 4189797 2115492..2115965 1 NC_008253.1 antirestriction protein 2115965 4189797 ECP_2044 Escherichia coli 536 antirestriction protein YP_669944.1 2115492 D 362663 CDS YP_669945.1 110642215 4189798 2115981..2116457 1 NC_008253.1 radC-like protein YeeS 2116457 4189798 ECP_2045 Escherichia coli 536 radC-like protein YeeS YP_669945.1 2115981 D 362663 CDS YP_669946.1 110642216 4189799 2116526..2116747 1 NC_008253.1 hypothetical protein 2116747 4189799 ECP_2046 Escherichia coli 536 hypothetical protein YP_669946.1 2116526 D 362663 CDS YP_669947.1 110642217 4189800 2116821..2117189 1 NC_008253.1 hypothetical protein 2117189 4189800 ECP_2047 Escherichia coli 536 hypothetical protein YP_669947.1 2116821 D 362663 CDS YP_669948.1 110642218 4189801 2117278..2117652 1 NC_008253.1 hypothetical protein 2117652 4189801 ECP_2048 Escherichia coli 536 hypothetical protein YP_669948.1 2117278 D 362663 CDS YP_669949.1 110642219 4189802 2117649..2117843 1 NC_008253.1 hypothetical protein 2117843 4189802 ECP_2049 Escherichia coli 536 hypothetical protein YP_669949.1 2117649 D 362663 CDS YP_669950.1 110642220 4189803 2118284..2118640 1 NC_008253.1 hypothetical protein 2118640 4189803 ECP_2050 Escherichia coli 536 hypothetical protein YP_669950.1 2118284 D 362663 CDS YP_669951.1 110642221 4189804 complement(2118741..2119070) 1 NC_008253.1 hypothetical protein 2119070 4189804 ECP_2051 Escherichia coli 536 hypothetical protein YP_669951.1 2118741 R 362663 CDS YP_669952.1 110642222 4189805 complement(2119242..2120300) 1 NC_008253.1 hypothetical protein 2120300 4189805 ECP_2052 Escherichia coli 536 hypothetical protein YP_669952.1 2119242 R 362663 CDS YP_669953.1 110642223 4189806 complement(2120498..2120971) 1 NC_008253.1 DNA gyrase inhibitor 2120971 4189806 ECP_2053 Escherichia coli 536 DNA gyrase inhibitor YP_669953.1 2120498 R 362663 CDS YP_669954.1 110642224 4189807 complement(2121090..2122256) 1 NC_008253.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2122256 dacD 4189807 dacD Escherichia coli 536 D-alanyl-D-alanine carboxypeptidase YP_669954.1 2121090 R 362663 CDS YP_669955.1 110642225 4189808 2122465..2123892 1 NC_008253.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2123892 sbcB 4189808 sbcB Escherichia coli 536 exonuclease I YP_669955.1 2122465 D 362663 CDS YP_669956.1 110642226 4189809 complement(2123966..2124421) 1 NC_008253.1 similar to C-terminal part of amino acid permease YeeF; hypothetical protein 2124421 4189809 ECP_2056 Escherichia coli 536 hypothetical protein YP_669956.1 2123966 R 362663 CDS YP_669957.1 110642227 4189810 complement(2124477..2125328) 1 NC_008253.1 similar to N-terminal part of amino acid permease YeeF; hypothetical protein 2125328 4189810 ECP_2057 Escherichia coli 536 hypothetical protein YP_669957.1 2124477 R 362663 CDS YP_669958.1 110642228 4191287 complement(2125595..2126524) 1 NC_008253.1 LysR family transcriptional regulator 2126524 4191287 ECP_2058 Escherichia coli 536 LysR family transcriptional regulator YP_669958.1 2125595 R 362663 CDS YP_669959.1 110642229 4191288 complement(2126570..2127394) 1 NC_008253.1 protein YeeZ 2127394 4191288 ECP_2059 Escherichia coli 536 protein YeeZ YP_669959.1 2126570 R 362663 CDS YP_669960.1 110642230 4191289 complement(2127477..2127731) 1 NC_008253.1 hypothetical protein 2127731 4191289 ECP_2060 Escherichia coli 536 hypothetical protein YP_669960.1 2127477 R 362663 CDS YP_669961.1 110642231 4191290 complement(2127728..2127979) 1 NC_008253.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2127979 4191290 ECP_2061 Escherichia coli 536 antitoxin YefM YP_669961.1 2127728 R 362663 CDS YP_669962.1 110642232 4191291 2128458..2129357 1 NC_008253.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2129357 hisG 4191291 hisG Escherichia coli 536 ATP phosphoribosyltransferase YP_669962.1 2128458 D 362663 CDS YP_669963.1 110642233 4191292 2129363..2130667 1 NC_008253.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2130667 hisD 4191292 hisD Escherichia coli 536 histidinol dehydrogenase YP_669963.1 2129363 D 362663 CDS YP_669964.1 110642234 4191293 2130664..2131734 1 NC_008253.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2131734 4191293 ECP_2064 Escherichia coli 536 histidinol-phosphate aminotransferase YP_669964.1 2130664 D 362663 CDS YP_669965.1 110642235 4191294 2131734..2132801 1 NC_008253.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2132801 4191294 ECP_2065 Escherichia coli 536 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_669965.1 2131734 D 362663 CDS YP_669966.1 110642236 4191295 2132801..2133391 1 NC_008253.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2133391 hisH 4191295 hisH Escherichia coli 536 imidazole glycerol phosphate synthase subunit HisH YP_669966.1 2132801 D 362663 CDS YP_669967.1 110642237 4191296 2133391..2134128 1 NC_008253.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2134128 4191296 ECP_2067 Escherichia coli 536 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_669967.1 2133391 D 362663 CDS YP_669968.1 110642238 4191297 2134110..2134886 1 NC_008253.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2134886 4191297 ECP_2068 Escherichia coli 536 imidazole glycerol phosphate synthase subunit HisF YP_669968.1 2134110 D 362663 CDS YP_669969.1 110642239 4191298 2134880..2135491 1 NC_008253.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2135491 4191298 ECP_2069 Escherichia coli 536 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_669969.1 2134880 D 362663 CDS YP_669970.1 110642240 4191299 complement(2135677..2136654) 1 NC_008253.1 chain length determinant protein 2136654 4191299 ECP_2070 Escherichia coli 536 chain length determinant protein YP_669970.1 2135677 R 362663 CDS YP_669971.1 110642241 4191300 complement(2136797..2137963) 1 NC_008253.1 UDP-glucose 6-dehydrogenase 2137963 4191300 ECP_2071 Escherichia coli 536 UDP-glucose 6-dehydrogenase YP_669971.1 2136797 R 362663 CDS YP_669972.1 110642242 4191301 complement(2138213..2139619) 1 NC_008253.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2139619 4191301 ECP_2072 Escherichia coli 536 6-phosphogluconate dehydrogenase YP_669972.1 2138213 R 362663 CDS YP_669973.1 110642243 4191302 complement(2139782..2141152) 1 NC_008253.1 phosphomannomutase 2141152 4191302 ECP_2073 Escherichia coli 536 phosphomannomutase YP_669973.1 2139782 R 362663 CDS YP_669974.1 110642244 4191303 complement(2141235..2142686) 1 NC_008253.1 mannose-1-phosphate guanylyltransferase 2142686 4191303 ECP_2074 Escherichia coli 536 mannose-1-phosphate guanylyltransferase YP_669974.1 2141235 R 362663 CDS YP_669975.1 110642245 4191304 complement(2142664..2143869) 1 NC_008253.1 glycosyltransferase 2143869 4191304 ECP_2075 Escherichia coli 536 glycosyltransferase YP_669975.1 2142664 R 362663 CDS YP_669976.1 110642246 4191305 complement(2143890..2144897) 1 NC_008253.1 UDP-glucose 4-epimerase 2144897 4191305 ECP_2076 Escherichia coli 536 UDP-glucose 4-epimerase YP_669976.1 2143890 R 362663 CDS YP_669977.1 110642247 4191306 complement(2144914..2146059) 1 NC_008253.1 glycosyltransferase 2146059 4191306 ECP_2077 Escherichia coli 536 glycosyltransferase YP_669977.1 2144914 R 362663 CDS YP_669978.1 110642248 4188806 complement(2146046..2147077) 1 NC_008253.1 glycosyltransferase 2147077 4188806 ECP_2078 Escherichia coli 536 glycosyltransferase YP_669978.1 2146046 R 362663 CDS YP_669979.1 110642249 4188807 complement(2147074..2147934) 1 NC_008253.1 glycosyltransferase 2147934 4188807 ECP_2079 Escherichia coli 536 glycosyltransferase YP_669979.1 2147074 R 362663 CDS YP_669980.1 110642250 4188808 complement(2147940..2149283) 1 NC_008253.1 antigen polymerase 2149283 4188808 ECP_2080 Escherichia coli 536 antigen polymerase YP_669980.1 2147940 R 362663 CDS YP_669981.1 110642251 4188809 complement(2149283..2150521) 1 NC_008253.1 O antigen flippase 2150521 4188809 ECP_2081 Escherichia coli 536 O antigen flippase YP_669981.1 2149283 R 362663 CDS YP_669982.1 110642252 4188810 complement(2150896..2151789) 1 NC_008253.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 2151789 4188810 ECP_2082 Escherichia coli 536 UTP-glucose-1-phosphate uridylyltransferase YP_669982.1 2150896 R 362663 CDS YP_669983.1 110642253 4188811 complement(2151964..2153358) 1 NC_008253.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2153358 wcaM 4188811 wcaM Escherichia coli 536 colanic acid biosynthesis protein YP_669983.1 2151964 R 362663 CDS YP_669984.1 110642254 4188812 complement(2153369..2154589) 1 NC_008253.1 colanic acid biosynthesis glycosyl transferase WcaL 2154589 4188812 ECP_2084 Escherichia coli 536 colanic acid biosynthesis glycosyl transferase WcaL YP_669984.1 2153369 R 362663 CDS YP_669985.1 110642255 4188813 complement(2154586..2155866) 1 NC_008253.1 pyruvyl transferase 2155866 4188813 ECP_2085 Escherichia coli 536 pyruvyl transferase YP_669985.1 2154586 R 362663 CDS YP_669986.1 110642256 4188814 complement(2156432..2157910) 1 NC_008253.1 colanic acid exporter 2157910 4188814 ECP_2086 Escherichia coli 536 colanic acid exporter YP_669986.1 2156432 R 362663 CDS YP_669987.1 110642257 4188815 complement(2157912..2159306) 1 NC_008253.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2159306 4188815 ECP_2087 Escherichia coli 536 UDP-glucose lipid carrier transferase YP_669987.1 2157912 R 362663 CDS YP_669988.1 110642258 4188816 complement(2159361..2160731) 1 NC_008253.1 phosphomannomutase 2160731 4188816 ECP_2088 Escherichia coli 536 phosphomannomutase YP_669988.1 2159361 R 362663 CDS YP_669989.1 110642259 4188817 complement(2160924..2162360) 1 NC_008253.1 mannose-1-phosphate guanylyltransferase 2162360 4188817 ECP_2089 Escherichia coli 536 mannose-1-phosphate guanylyltransferase YP_669989.1 2160924 R 362663 CDS YP_669990.1 110642260 4188818 complement(2162363..2163586) 1 NC_008253.1 glycosyl transferase family protein 2163586 4188818 ECP_2090 Escherichia coli 536 glycosyl transferase family protein YP_669990.1 2162363 R 362663 CDS YP_669991.1 110642261 4188819 complement(2163583..2164062) 1 NC_008253.1 GDP-mannose mannosyl hydrolase 2164062 4188819 ECP_2091 Escherichia coli 536 GDP-mannose mannosyl hydrolase YP_669991.1 2163583 R 362663 CDS YP_669992.1 110642262 4188820 complement(2164065..2165030) 1 NC_008253.1 GDP-fucose synthetase 2165030 4188820 ECP_2092 Escherichia coli 536 GDP-fucose synthetase YP_669992.1 2164065 R 362663 CDS YP_669993.1 110642263 4188821 complement(2165033..2166154) 1 NC_008253.1 GDP-mannose 4,6-dehydratase 2166154 4188821 ECP_2093 Escherichia coli 536 GDP-mannose 4,6-dehydratase YP_669993.1 2165033 R 362663 CDS YP_669994.1 110642264 4188822 complement(2166181..2166729) 1 NC_008253.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2166729 4188822 ECP_2094 Escherichia coli 536 colanic acid biosynthesis acetyltransferase WcaF YP_669994.1 2166181 R 362663 CDS YP_669995.1 110642265 4188823 complement(2166745..2167491) 1 NC_008253.1 glycosyl transferase family protein 2167491 4188823 ECP_2095 Escherichia coli 536 glycosyl transferase family protein YP_669995.1 2166745 R 362663 CDS YP_669996.1 110642266 4188824 complement(2167502..2168719) 1 NC_008253.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2168719 wcaD 4188824 wcaD Escherichia coli 536 colanic acid biosynthesis protein YP_669996.1 2167502 R 362663 CDS YP_669997.1 110642267 4187717 complement(2168694..2169911) 1 NC_008253.1 glycosyl transferase family protein 2169911 4187717 ECP_2097 Escherichia coli 536 glycosyl transferase family protein YP_669997.1 2168694 R 362663 CDS YP_669998.1 110642268 4187718 complement(2169908..2170396) 1 NC_008253.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2170396 4187718 ECP_2098 Escherichia coli 536 colanic acid biosynthesis acetyltransferase WcaB YP_669998.1 2169908 R 362663 CDS YP_669999.1 110642269 4187719 complement(2170399..2171238) 1 NC_008253.1 glycosyl transferase family protein 2171238 4187719 ECP_2099 Escherichia coli 536 glycosyl transferase family protein YP_669999.1 2170399 R 362663 CDS YP_670000.1 110642270 4187720 complement(2171331..2173493) 1 NC_008253.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2173493 4187720 ECP_2100 Escherichia coli 536 tyrosine kinase YP_670000.1 2171331 R 362663 CDS YP_670001.1 110642271 4187721 complement(2173496..2173939) 1 NC_008253.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2173939 4187721 ECP_2101 Escherichia coli 536 tyrosine phosphatase YP_670001.1 2173496 R 362663 CDS YP_670002.1 110642272 4187722 complement(2173945..2175084) 1 NC_008253.1 polysaccharide export protein wza 2175084 4187722 ECP_2102 Escherichia coli 536 polysaccharide export protein wza YP_670002.1 2173945 R 362663 CDS YP_670003.1 110642273 4187723 2175743..2177326 1 NC_008253.1 hypothetical protein 2177326 4187723 ECP_2103 Escherichia coli 536 hypothetical protein YP_670003.1 2175743 D 362663 CDS YP_670004.1 110642274 4187724 complement(2177619..2179472) 1 NC_008253.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2179472 4187724 ECP_2104 Escherichia coli 536 assembly protein YP_670004.1 2177619 R 362663 CDS YP_670005.1 110642275 4187725 complement(2179494..2180075) 1 NC_008253.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2180075 dcd 4187725 dcd Escherichia coli 536 deoxycytidine triphosphate deaminase YP_670005.1 2179494 R 362663 CDS YP_670006.1 110642276 4187726 complement(2180167..2180808) 1 NC_008253.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2180808 4187726 ECP_2106 Escherichia coli 536 uridine kinase YP_670006.1 2180167 R 362663 CDS YP_670007.1 110642277 4187727 2181126..2184443 1 NC_008253.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2184443 4187727 ECP_2107 Escherichia coli 536 sensor protein YP_670007.1 2181126 D 362663 CDS YP_670008.1 110642278 4187728 complement(2184553..2185401) 1 NC_008253.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2185401 4187728 ECP_2108 Escherichia coli 536 3-methyladenine DNA glycosylase YP_670008.1 2184553 R 362663 CDS YP_670009.1 110642279 4187729 2185535..2186887 1 NC_008253.1 chaperone 2186887 4187729 ECP_2109 Escherichia coli 536 chaperone YP_670009.1 2185535 D 362663 CDS YP_670010.1 110642280 4187730 complement(2186900..2188840) 1 NC_008253.1 hypothetical protein 2188840 4187730 ECP_2110 Escherichia coli 536 hypothetical protein YP_670010.1 2186900 R 362663 CDS YP_670011.1 110642281 4187731 complement(2188837..2189598) 1 NC_008253.1 hypothetical protein 2189598 4187731 ECP_2111 Escherichia coli 536 hypothetical protein YP_670011.1 2188837 R 362663 CDS YP_670012.1 110642282 4187732 complement(2189595..2189759) 1 NC_008253.1 hypothetical protein 2189759 4187732 ECP_2112 Escherichia coli 536 hypothetical protein YP_670012.1 2189595 R 362663 CDS YP_670013.1 110642283 4187733 complement(2189838..2190254) 1 NC_008253.1 hypothetical protein 2190254 4187733 ECP_2113 Escherichia coli 536 hypothetical protein YP_670013.1 2189838 R 362663 CDS YP_670014.1 110642284 4187734 2191135..2192382 1 NC_008253.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2192382 4187734 ECP_2114 Escherichia coli 536 multidrug efflux system subunit MdtA YP_670014.1 2191135 D 362663 CDS YP_670015.1 110642285 4187735 2192382..2195504 1 NC_008253.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2195504 4187735 ECP_2115 Escherichia coli 536 multidrug efflux system subunit MdtB YP_670015.1 2192382 D 362663 CDS YP_670016.1 110642286 4187736 2195505..2198582 1 NC_008253.1 efflux transporter; Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2198582 4187736 ECP_2116 Escherichia coli 536 multidrug efflux system subunit MdtC YP_670016.1 2195505 D 362663 CDS YP_670017.1 110642287 4191668 2198583..2199998 1 NC_008253.1 multidrug efflux system protein MdtE 2199998 4191668 ECP_2117 Escherichia coli 536 multidrug efflux system protein MdtE YP_670017.1 2198583 D 362663 CDS YP_670018.1 110642288 4191669 2199995..2201398 1 NC_008253.1 signal transduction histidine-protein kinase BaeS 2201398 4191669 ECP_2118 Escherichia coli 536 signal transduction histidine-protein kinase BaeS YP_670018.1 2199995 D 362663 CDS YP_670019.1 110642289 4191670 2201395..2202117 1 NC_008253.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2202117 4191670 ECP_2119 Escherichia coli 536 DNA-binding transcriptional regulator BaeR YP_670019.1 2201395 D 362663 CDS YP_670020.1 110642290 4191671 2202297..2202629 1 NC_008253.1 hypothetical protein 2202629 4191671 ECP_2120 Escherichia coli 536 hypothetical protein YP_670020.1 2202297 D 362663 CDS YP_670021.1 110642291 4191672 complement(2202754..2203368) 1 NC_008253.1 hypothetical protein 2203368 4191672 ECP_2121 Escherichia coli 536 hypothetical protein YP_670021.1 2202754 R 362663 CDS YP_670022.1 110642292 4191673 complement(2203420..2205528) 1 NC_008253.1 hypothetical protein 2205528 4191673 ECP_2122 Escherichia coli 536 hypothetical protein YP_670022.1 2203420 R 362663 CDS YP_670023.1 110642293 4191674 complement(2205539..2206255) 1 NC_008253.1 hypothetical protein 2206255 4191674 ECP_2123 Escherichia coli 536 hypothetical protein YP_670023.1 2205539 R 362663 CDS YP_670024.1 110642294 4191675 complement(2206255..2207469) 1 NC_008253.1 hypothetical protein 2207469 4191675 ECP_2124 Escherichia coli 536 hypothetical protein YP_670024.1 2206255 R 362663 CDS YP_670025.1 110642295 4191676 2207957..2209318 1 NC_008253.1 protease YegQ 2209318 4191676 ECP_2125 Escherichia coli 536 protease YegQ YP_670025.1 2207957 D 362663 CDS YP_670026.1 110642296 4191677 complement(2209818..2210135) 1 NC_008253.1 hypothetical protein 2210135 4191677 ECP_2126 Escherichia coli 536 hypothetical protein YP_670026.1 2209818 R 362663 CDS YP_670027.1 110642297 4191678 2210551..2211450 1 NC_008253.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2211450 4191678 ECP_2127 Escherichia coli 536 lipid kinase YP_670027.1 2210551 D 362663 CDS YP_670028.1 110642298 4191679 complement(2211532..2212305) 1 NC_008253.1 galactitol utilization operon repressor 2212305 4191679 ECP_2128 Escherichia coli 536 galactitol utilization operon repressor YP_670028.1 2211532 R 362663 CDS YP_670029.1 110642299 4191680 complement(2212411..2213358) 1 NC_008253.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2213358 4191680 ECP_2129 Escherichia coli 536 galactitol-1-phosphate dehydrogenase YP_670029.1 2212411 R 362663 CDS YP_670030.1 110642300 4191681 complement(2213500..2214855) 1 NC_008253.1 PTS system galactitol-specific transporter subunit IIC 2214855 4191681 ECP_2130 Escherichia coli 536 PTS system galactitol-specific transporter subunit IIC YP_670030.1 2213500 R 362663 CDS YP_670031.1 110642301 4191682 complement(2214859..2215143) 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; galactitol-specific PTS system component IIB 2215143 4191682 ECP_2131 Escherichia coli 536 galactitol-specific PTS system component IIB YP_670031.1 2214859 R 362663 CDS YP_670032.1 110642302 4191683 complement(2215174..2215626) 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; galactitol-specific PTS system component IIA 2215626 4191683 ECP_2132 Escherichia coli 536 galactitol-specific PTS system component IIA YP_670032.1 2215174 R 362663 CDS YP_670033.1 110642303 4191684 complement(2215636..2216898) 1 NC_008253.1 tagatose 6-phosphate kinase gatZ 2216898 4191684 ECP_2133 Escherichia coli 536 tagatose 6-phosphate kinase gatZ YP_670033.1 2215636 R 362663 CDS YP_670034.1 110642304 4191685 complement(2216927..2217781) 1 NC_008253.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2217781 gatY 4191685 gatY Escherichia coli 536 tagatose-bisphosphate aldolase YP_670034.1 2216927 R 362663 CDS YP_670035.1 110642305 4191686 complement(2218008..2219060) 1 NC_008253.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2219060 4191686 ECP_2135 Escherichia coli 536 fructose-bisphosphate aldolase YP_670035.1 2218008 R 362663 CDS YP_670036.1 110642306 4187641 2219317..2220594 1 NC_008253.1 nucleoside transporter YegT 2220594 4187641 ECP_2136 Escherichia coli 536 nucleoside transporter YegT YP_670036.1 2219317 D 362663 CDS YP_670037.1 110642307 4187642 2220591..2221595 1 NC_008253.1 hypothetical protein 2221595 4187642 ECP_2137 Escherichia coli 536 hypothetical protein YP_670037.1 2220591 D 362663 CDS YP_670038.1 110642308 4187643 2221592..2222557 1 NC_008253.1 sugar kinase 2222557 4187643 ECP_2138 Escherichia coli 536 sugar kinase YP_670038.1 2221592 D 362663 CDS YP_670039.1 110642309 4187644 complement(2222531..2223277) 1 NC_008253.1 transcriptional regulator YegW 2223277 4187644 ECP_2139 Escherichia coli 536 transcriptional regulator YegW YP_670039.1 2222531 R 362663 CDS YP_670040.1 110642310 4187645 complement(2223329..2224147) 1 NC_008253.1 hypothetical protein 2224147 4187645 ECP_2140 Escherichia coli 536 hypothetical protein YP_670040.1 2223329 R 362663 CDS YP_670041.1 110642311 4187646 complement(2224212..2225012) 1 NC_008253.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2225012 4187646 ECP_2141 Escherichia coli 536 phosphomethylpyrimidine kinase YP_670041.1 2224212 R 362663 CDS YP_670042.1 110642312 4187647 complement(2225009..2225797) 1 NC_008253.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2225797 4187647 ECP_2142 Escherichia coli 536 hydroxyethylthiazole kinase YP_670042.1 2225009 R 362663 CDS YP_670043.1 110642313 4187648 complement(2226020..2226292) 1 NC_008253.1 hypothetical protein 2226292 4187648 ECP_2143 Escherichia coli 536 hypothetical protein YP_670043.1 2226020 R 362663 CDS YP_670044.1 110642314 4187649 2226413..2227237 1 NC_008253.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2227237 4187649 ECP_2144 Escherichia coli 536 nickel/cobalt efflux protein RcnA YP_670044.1 2226413 D 362663 CDS YP_670045.1 110642315 4187650 2227456..2227794 1 NC_008253.1 hypothetical protein 2227794 4187650 ECP_2145 Escherichia coli 536 hypothetical protein YP_670045.1 2227456 D 362663 CDS YP_670046.1 110642316 4187651 complement(2227876..2228910) 1 NC_008253.1 hypothetical protein 2228910 4187651 ECP_2146 Escherichia coli 536 hypothetical protein YP_670046.1 2227876 R 362663 CDS YP_670047.1 110642317 4187652 complement(2228926..2231406) 1 NC_008253.1 outer membrane usher protein YehB 2231406 4187652 ECP_2147 Escherichia coli 536 outer membrane usher protein YehB YP_670047.1 2228926 R 362663 CDS YP_670048.1 110642318 4187653 complement(2231422..2232096) 1 NC_008253.1 fimbrial chaperone 2232096 4187653 ECP_2148 Escherichia coli 536 fimbrial chaperone YP_670048.1 2231422 R 362663 CDS YP_670049.1 110642319 4187654 complement(2232177..2232719) 1 NC_008253.1 hypothetical protein 2232719 4187654 ECP_2149 Escherichia coli 536 hypothetical protein YP_670049.1 2232177 R 362663 CDS YP_670050.1 110642320 4187655 complement(2233013..2233294) 1 NC_008253.1 hypothetical protein 2233294 4187655 ECP_2150 Escherichia coli 536 hypothetical protein YP_670050.1 2233013 R 362663 CDS YP_670051.1 110642321 4187656 complement(2233557..2234666) 1 NC_008253.1 ATPase 2234666 4187656 ECP_2151 Escherichia coli 536 ATPase YP_670051.1 2233557 R 362663 CDS YP_670052.1 110642322 4187657 2234789..2236831 1 NC_008253.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2236831 metG 4187657 metG Escherichia coli 536 methionyl-tRNA synthetase YP_670052.1 2234789 D 362663 CDS YP_670053.1 110642323 4187658 2236972..2240760 1 NC_008253.1 molybdate metabolism regulator 2240760 4187658 ECP_2153 Escherichia coli 536 molybdate metabolism regulator YP_670053.1 2236972 D 362663 CDS YP_670054.1 110642324 4187659 2240770..2244402 1 NC_008253.1 hypothetical protein 2244402 4187659 ECP_2154 Escherichia coli 536 hypothetical protein YP_670054.1 2240770 D 362663 CDS YP_670055.1 110642325 4187660 2244463..2244648 1 NC_008253.1 hypothetical protein 2244648 4187660 ECP_2155 Escherichia coli 536 hypothetical protein YP_670055.1 2244463 D 362663 CDS YP_670056.1 110642326 4191170 2245483..2246571 1 NC_008253.1 hypothetical protein 2246571 4191170 ECP_2156 Escherichia coli 536 hypothetical protein YP_670056.1 2245483 D 362663 CDS YP_670057.1 110642327 4191171 2246582..2248861 1 NC_008253.1 hypothetical protein 2248861 4191171 ECP_2157 Escherichia coli 536 hypothetical protein YP_670057.1 2246582 D 362663 CDS YP_670058.1 110642328 4191172 2248854..2249990 1 NC_008253.1 hypothetical protein 2249990 4191172 ECP_2158 Escherichia coli 536 hypothetical protein YP_670058.1 2248854 D 362663 CDS YP_670059.1 110642329 4191173 2249987..2251777 1 NC_008253.1 hypothetical protein 2251777 4191173 ECP_2159 Escherichia coli 536 hypothetical protein YP_670059.1 2249987 D 362663 CDS YP_670060.1 110642330 4191174 2251740..2251976 1 NC_008253.1 hypothetical protein 2251976 4191174 ECP_2160 Escherichia coli 536 hypothetical protein YP_670060.1 2251740 D 362663 CDS YP_670061.1 110642331 4191175 2252101..2252562 1 NC_008253.1 lipoprotein YehR 2252562 4191175 ECP_2161 Escherichia coli 536 lipoprotein YehR YP_670061.1 2252101 D 362663 CDS YP_670062.1 110642332 4191176 complement(2252603..2253073) 1 NC_008253.1 hypothetical protein 2253073 4191176 ECP_2162 Escherichia coli 536 hypothetical protein YP_670062.1 2252603 R 362663 CDS YP_670063.1 110642333 4191177 complement(2253120..2253839) 1 NC_008253.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2253839 4191177 ECP_2163 Escherichia coli 536 two-component response-regulatory protein YehT YP_670063.1 2253120 R 362663 CDS YP_670064.1 110642334 4191178 complement(2253836..2255521) 1 NC_008253.1 hypothetical protein 2255521 4191178 ECP_2164 Escherichia coli 536 hypothetical protein YP_670064.1 2253836 R 362663 CDS YP_670065.1 110642335 4191179 2255743..2256474 1 NC_008253.1 MerR family transcriptional regulator 2256474 4191179 ECP_2165 Escherichia coli 536 MerR family transcriptional regulator YP_670065.1 2255743 D 362663 CDS YP_670066.1 110642336 4191180 2256534..2256641 1 NC_008253.1 hypothetical protein 2256641 4191180 ECP_2166 Escherichia coli 536 hypothetical protein YP_670066.1 2256534 D 362663 CDS YP_670067.1 110642337 4191181 complement(2256622..2257353) 1 NC_008253.1 ABC transporter permease 2257353 4191181 ECP_2167 Escherichia coli 536 ABC transporter permease YP_670067.1 2256622 R 362663 CDS YP_670068.1 110642338 4191182 complement(2257497..2258285) 1 NC_008253.1 ABC transporter ATP-binding protein 2258285 4191182 ECP_2168 Escherichia coli 536 ABC transporter ATP-binding protein YP_670068.1 2257497 R 362663 CDS YP_670069.1 110642339 4191183 complement(2258278..2259435) 1 NC_008253.1 ABC transporter permease 2259435 4191183 ECP_2169 Escherichia coli 536 ABC transporter permease YP_670069.1 2258278 R 362663 CDS YP_670070.1 110642340 4191184 complement(2259442..2260359) 1 NC_008253.1 hypothetical protein 2260359 4191184 ECP_2170 Escherichia coli 536 hypothetical protein YP_670070.1 2259442 R 362663 CDS YP_670071.1 110642341 4191185 complement(2260549..2262918) 1 NC_008253.1 periplasmic beta-glucosidase 2262918 4191185 ECP_2171 Escherichia coli 536 periplasmic beta-glucosidase YP_670071.1 2260549 R 362663 CDS YP_670072.1 110642342 4191186 2263042..2264757 1 NC_008253.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2264757 4191186 ECP_2172 Escherichia coli 536 D-lactate dehydrogenase YP_670072.1 2263042 D 362663 CDS YP_670073.1 110642343 4191187 complement(2264796..2265737) 1 NC_008253.1 penicillin-binding protein 7 precursor; specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2265737 pbpG 4191187 pbpG Escherichia coli 536 D-alanyl-D-alanine endopeptidase YP_670073.1 2264796 R 362663 CDS YP_670074.1 110642344 4191188 complement(2265902..2266489) 1 NC_008253.1 hypothetical protein 2266489 4191188 ECP_2174 Escherichia coli 536 hypothetical protein YP_670074.1 2265902 R 362663 CDS YP_670075.1 110642345 4189830 2266659..2267237 1 NC_008253.1 DedA family membrane protein 2267237 4189830 ECP_2175 Escherichia coli 536 DedA family membrane protein YP_670075.1 2266659 D 362663 CDS YP_670076.1 110642346 4189831 complement(2267357..2268118) 1 NC_008253.1 acetoin dehydrogenase 2268118 4189831 ECP_2176 Escherichia coli 536 acetoin dehydrogenase YP_670076.1 2267357 R 362663 CDS YP_670077.1 110642347 4189832 complement(2268171..2269688) 1 NC_008253.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2269688 4189832 ECP_2177 Escherichia coli 536 multidrug resistance outer membrane protein MdtQ YP_670077.1 2268171 R 362663 CDS YP_670078.1 110642348 4189833 complement(2270066..2270275) 1 NC_008253.1 hypothetical protein 2270275 4189833 ECP_2178 Escherichia coli 536 hypothetical protein YP_670078.1 2270066 R 362663 CDS YP_670079.1 110642349 4189834 complement(2270303..2271253) 1 NC_008253.1 tRNA-dihydrouridine synthase C 2271253 4189834 ECP_2179 Escherichia coli 536 tRNA-dihydrouridine synthase C YP_670079.1 2270303 R 362663 CDS YP_670080.1 110642350 4189835 2271492..2271890 1 NC_008253.1 hypothetical protein 2271890 4189835 ECP_2180 Escherichia coli 536 hypothetical protein YP_670080.1 2271492 D 362663 CDS YP_670081.1 110642351 4189836 2271887..2272582 1 NC_008253.1 hypothetical protein 2272582 4189836 ECP_2181 Escherichia coli 536 hypothetical protein YP_670081.1 2271887 D 362663 CDS YP_670082.1 110642352 4189837 2272712..2273596 1 NC_008253.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2273596 4189837 ECP_2182 Escherichia coli 536 cytidine deaminase YP_670082.1 2272712 D 362663 CDS YP_670083.1 110642353 4189838 2273746..2274465 1 NC_008253.1 hypothetical protein 2274465 4189838 ECP_2183 Escherichia coli 536 hypothetical protein YP_670083.1 2273746 D 362663 CDS YP_670084.1 110642354 4189839 2274468..2274707 1 NC_008253.1 hypothetical protein 2274707 4189839 ECP_2184 Escherichia coli 536 hypothetical protein YP_670084.1 2274468 D 362663 CDS YP_670085.1 110642355 4189840 2274901..2276139 1 NC_008253.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2276139 4189840 ECP_2185 Escherichia coli 536 oxidoreductase YP_670085.1 2274901 D 362663 CDS YP_670086.1 110642356 4189841 2276133..2277368 1 NC_008253.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2277368 4189841 ECP_2186 Escherichia coli 536 dihydropyrimidine dehydrogenase YP_670086.1 2276133 D 362663 CDS YP_670087.1 110642357 4189842 complement(2277611..2278621) 1 NC_008253.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2278621 mglC 4189842 mglC Escherichia coli 536 beta-methylgalactoside transporter inner membrane protein YP_670087.1 2277611 R 362663 CDS YP_670088.1 110642358 4189843 complement(2278637..2280157) 1 NC_008253.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2280157 4189843 ECP_2188 Escherichia coli 536 galactose/methyl galaxtoside transporter ATP-binding protein YP_670088.1 2278637 R 362663 CDS YP_670089.1 110642359 4189844 complement(2280218..2281216) 1 NC_008253.1 D-galactose-binding periplasmic protein 2281216 4189844 ECP_2189 Escherichia coli 536 D-galactose-binding periplasmic protein YP_670089.1 2280218 R 362663 CDS YP_670090.1 110642360 4189845 complement(2281496..2282536) 1 NC_008253.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2282536 4189845 ECP_2190 Escherichia coli 536 DNA-binding transcriptional regulator GalS YP_670090.1 2281496 R 362663 CDS YP_670091.1 110642361 4189846 2282526..2282729 1 NC_008253.1 hypothetical protein 2282729 4189846 ECP_2191 Escherichia coli 536 hypothetical protein YP_670091.1 2282526 D 362663 CDS YP_670092.1 110642362 4189847 complement(2282678..2283952) 1 NC_008253.1 hypothetical protein 2283952 4189847 ECP_2192 Escherichia coli 536 hypothetical protein YP_670092.1 2282678 R 362663 CDS YP_670093.1 110642363 4189848 complement(2283852..2284520) 1 NC_008253.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2284520 folE 4189848 folE Escherichia coli 536 GTP cyclohydrolase I YP_670093.1 2283852 R 362663 CDS YP_670094.1 110642364 4189849 2284778..2285614 1 NC_008253.1 hypothetical protein 2285614 4189849 ECP_2194 Escherichia coli 536 hypothetical protein YP_670094.1 2284778 D 362663 CDS YP_670095.1 110642365 4187378 complement(2285646..2287637) 1 NC_008253.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2287637 4187378 ECP_2195 Escherichia coli 536 colicin I receptor YP_670095.1 2285646 R 362663 CDS YP_670096.1 110642366 4187379 complement(2287929..2289398) 1 NC_008253.1 lysine transporter 2289398 4187379 ECP_2196 Escherichia coli 536 lysine transporter YP_670096.1 2287929 R 362663 CDS YP_670097.1 110642367 4187380 complement(2289603..2290484) 1 NC_008253.1 DNA-binding transcriptional regulator 2290484 4187380 ECP_2197 Escherichia coli 536 DNA-binding transcriptional regulator YP_670097.1 2289603 R 362663 CDS YP_670098.1 110642368 4187381 2290583..2291632 1 NC_008253.1 hypothetical protein 2291632 4187381 ECP_2198 Escherichia coli 536 hypothetical protein YP_670098.1 2290583 D 362663 CDS YP_670099.1 110642369 4187382 2291706..2292563 1 NC_008253.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2292563 4187382 ECP_2199 Escherichia coli 536 endonuclease IV YP_670099.1 2291706 D 362663 CDS YP_670100.1 110642370 4187383 2292567..2293655 1 NC_008253.1 hypothetical protein 2293655 4187383 ECP_2200 Escherichia coli 536 hypothetical protein YP_670100.1 2292567 D 362663 CDS YP_670101.1 110642371 4187384 complement(2293757..2294962) 1 NC_008253.1 Na+ dependent nucleoside transporter-family protein 2294962 4187384 ECP_2201 Escherichia coli 536 Na+ dependent nucleoside transporter-family protein YP_670101.1 2293757 R 362663 CDS YP_670102.1 110642372 4187385 complement(2295062..2296003) 1 NC_008253.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2296003 rihB 4187385 rihB Escherichia coli 536 ribonucleoside hydrolase 2 YP_670102.1 2295062 R 362663 CDS YP_670103.1 110642373 4187386 2296172..2296831 1 NC_008253.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2296831 4187386 ECP_2203 Escherichia coli 536 DNA-binding transcriptional activator YeiL YP_670103.1 2296172 D 362663 CDS YP_670104.1 110642374 4187387 complement(2296898..2298148) 1 NC_008253.1 Na+ dependent nucleoside transporter-family protein 2298148 4187387 ECP_2204 Escherichia coli 536 Na+ dependent nucleoside transporter-family protein YP_670104.1 2296898 R 362663 CDS YP_670105.1 110642375 4187388 complement(2298242..2299180) 1 NC_008253.1 hypothetical protein 2299180 4187388 ECP_2205 Escherichia coli 536 hypothetical protein YP_670105.1 2298242 R 362663 CDS YP_670106.1 110642376 4187389 complement(2299168..2300109) 1 NC_008253.1 hypothetical protein 2300109 4187389 ECP_2206 Escherichia coli 536 hypothetical protein YP_670106.1 2299168 R 362663 CDS YP_670107.1 110642377 4187390 complement(2300565..2302256) 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2302256 4187390 ECP_2207 Escherichia coli 536 PTS system fructose-specific transporter subunit IIBC YP_670107.1 2300565 R 362663 CDS YP_670108.1 110642378 4187391 complement(2302273..2303211) 1 NC_008253.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2303211 fruK 4187391 fruK Escherichia coli 536 1-phosphofructokinase YP_670108.1 2302273 R 362663 CDS YP_670109.1 110642379 4187392 complement(2303211..2304341) 1 NC_008253.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional fructose-specific PTS IIA/HPr protein 2304341 4187392 ECP_2209 Escherichia coli 536 bifunctional fructose-specific PTS IIA/HPr protein YP_670109.1 2303211 R 362663 CDS YP_670110.1 110642380 4187393 2304709..2305890 1 NC_008253.1 sugar efflux transporter B 2305890 4187393 ECP_2210 Escherichia coli 536 sugar efflux transporter B YP_670110.1 2304709 D 362663 CDS YP_670111.1 110642381 4187394 complement(2305887..2306141) 1 NC_008253.1 hypothetical protein 2306141 4187394 ECP_2211 Escherichia coli 536 hypothetical protein YP_670111.1 2305887 R 362663 CDS YP_670112.1 110642382 4187395 2306296..2306868 1 NC_008253.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2306868 4187395 ECP_2212 Escherichia coli 536 elongation factor P YP_670112.1 2306296 D 362663 CDS YP_670113.1 110642383 4187396 2307091..2308557 1 NC_008253.1 oxidoreductase YeiQ 2308557 4187396 ECP_2213 Escherichia coli 536 oxidoreductase YeiQ YP_670113.1 2307091 D 362663 CDS YP_670114.1 110642384 4189278 2308675..2309661 1 NC_008253.1 cobalamin synthesis protein 2309661 4189278 ECP_2214 Escherichia coli 536 cobalamin synthesis protein YP_670114.1 2308675 D 362663 CDS YP_670115.1 110642385 4189279 2309700..2310413 1 NC_008253.1 hypothetical protein 2310413 4189279 ECP_2215 Escherichia coli 536 hypothetical protein YP_670115.1 2309700 D 362663 CDS YP_670116.1 110642386 4189280 2310825..2311391 1 NC_008253.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2311391 spr 4189280 spr Escherichia coli 536 outer membrane lipoprotein YP_670116.1 2310825 D 362663 CDS YP_670117.1 110642387 4189281 2311572..2313128 1 NC_008253.1 hypothetical protein 2313128 4189281 ECP_2217 Escherichia coli 536 hypothetical protein YP_670117.1 2311572 D 362663 CDS YP_670118.1 110642388 4189282 2313210..2315024 1 NC_008253.1 hypothetical protein 2315024 4189282 ECP_2218 Escherichia coli 536 hypothetical protein YP_670118.1 2313210 D 362663 CDS YP_670119.1 110642389 4189283 2315025..2316119 1 NC_008253.1 ABC transporter permease 2316119 4189283 ECP_2219 Escherichia coli 536 ABC transporter permease YP_670119.1 2315025 D 362663 CDS YP_670120.1 110642390 4189284 2316119..2317144 1 NC_008253.1 ABC transporter permease 2317144 4189284 ECP_2220 Escherichia coli 536 ABC transporter permease YP_670120.1 2316119 D 362663 CDS YP_670121.1 110642391 4189285 2317146..2318735 1 NC_008253.1 ABC transporter ATP-binding protein 2318735 4189285 ECP_2221 Escherichia coli 536 ABC transporter ATP-binding protein YP_670121.1 2317146 D 362663 CDS YP_670122.1 110642392 4189286 complement(2318739..2319083) 1 NC_008253.1 hypothetical protein 2319083 4189286 ECP_2222 Escherichia coli 536 hypothetical protein YP_670122.1 2318739 R 362663 CDS YP_670123.1 110642393 4189287 complement(2319416..2320606) 1 NC_008253.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2320606 4189287 ECP_2223 Escherichia coli 536 bicyclomycin/multidrug efflux system protein YP_670123.1 2319416 R 362663 CDS YP_670124.1 110642394 4189288 complement(2320634..2321329) 1 NC_008253.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2321329 4189288 ECP_2224 Escherichia coli 536 16S rRNA pseudouridylate synthase A YP_670124.1 2320634 R 362663 CDS YP_670125.1 110642395 4189289 2321479..2323239 1 NC_008253.1 hypothetical protein 2323239 4189289 ECP_2225 Escherichia coli 536 hypothetical protein YP_670125.1 2321479 D 362663 CDS YP_670126.1 110642396 4189290 2323364..2323648 1 NC_008253.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2323648 4189290 ECP_2226 Escherichia coli 536 50S ribosomal protein L25 YP_670126.1 2323364 D 362663 CDS YP_670127.1 110642397 4189291 complement(2323787..2324794) 1 NC_008253.1 nucleoid-associated protein NdpA 2324794 4189291 ECP_2227 Escherichia coli 536 nucleoid-associated protein NdpA YP_670127.1 2323787 R 362663 CDS YP_670128.1 110642398 4189292 2324976..2325203 1 NC_008253.1 hypothetical protein 2325203 4189292 ECP_2228 Escherichia coli 536 hypothetical protein YP_670128.1 2324976 D 362663 CDS YP_670129.1 110642399 4189293 2325223..2326983 1 NC_008253.1 sulfatase 2326983 4189293 ECP_2229 Escherichia coli 536 sulfatase YP_670129.1 2325223 D 362663 CDS YP_670130.1 110642400 4189295 complement(2327372..2327470) 1 NC_008253.1 hypothetical protein 2327470 4189295 ECP_2231 Escherichia coli 536 hypothetical protein YP_670130.1 2327372 R 362663 CDS YP_670131.1 110642401 4189296 complement(2327473..2327862) 1 NC_008253.1 hypothetical protein 2327862 4189296 ECP_2232 Escherichia coli 536 hypothetical protein YP_670131.1 2327473 R 362663 CDS YP_670132.1 110642402 4191745 2328265..2328912 1 NC_008253.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2328912 4191745 ECP_2233 Escherichia coli 536 transcriptional regulator NarP YP_670132.1 2328265 D 362663 CDS YP_670133.1 110642403 4191746 complement(2328947..2329831) 1 NC_008253.1 cytochrome c-type biogenesis protein CcmH 2329831 4191746 ECP_2234 Escherichia coli 536 cytochrome c-type biogenesis protein CcmH YP_670133.1 2328947 R 362663 CDS YP_670134.1 110642404 4191747 complement(2329923..2330552) 1 NC_008253.1 thiol:disulfide interchange protein DsbE 2330552 4191747 ECP_2235 Escherichia coli 536 thiol:disulfide interchange protein DsbE YP_670134.1 2329923 R 362663 CDS YP_670135.1 110642405 4191748 complement(2330549..2332492) 1 NC_008253.1 cytochrome c-type biogenesis protein CcmF 2332492 4191748 ECP_2236 Escherichia coli 536 cytochrome c-type biogenesis protein CcmF YP_670135.1 2330549 R 362663 CDS YP_670136.1 110642406 4191749 complement(2332489..2332968) 1 NC_008253.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2332968 4191749 ECP_2237 Escherichia coli 536 cytochrome c-type biogenesis protein CcmE YP_670136.1 2332489 R 362663 CDS YP_670137.1 110642407 4191750 complement(2332965..2333174) 1 NC_008253.1 heme exporter protein D; cytochrome c-type biogenesis protein CcmD 2333174 4191750 ECP_2238 Escherichia coli 536 cytochrome c-type biogenesis protein CcmD YP_670137.1 2332965 R 362663 CDS YP_670138.1 110642408 4191753 complement(2333951..2334613) 1 NC_008253.1 heme exporter protein B; cytochrome c-type biogenesis protein CcmB 2334613 4191753 ECP_2241 Escherichia coli 536 cytochrome c-type biogenesis protein CcmB YP_670138.1 2333951 R 362663 CDS YP_670139.1 110642409 4191754 complement(2334610..2335227) 1 NC_008253.1 heme exporter protein A; ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2335227 4191754 ECP_2242 Escherichia coli 536 cytochrome c biogenesis protein CcmA YP_670139.1 2334610 R 362663 CDS YP_670140.1 110642410 4191755 complement(2335246..2335848) 1 NC_008253.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2335848 4191755 ECP_2243 Escherichia coli 536 cytochrome c-type protein NapC YP_670140.1 2335246 R 362663 CDS YP_670141.1 110642411 4191756 complement(2335858..2336307) 1 NC_008253.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2336307 napB 4191756 napB Escherichia coli 536 citrate reductase cytochrome c-type subunit YP_670141.1 2335858 R 362663 CDS YP_670142.1 110642412 4191757 complement(2336304..2337167) 1 NC_008253.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2337167 napH 4191757 napH Escherichia coli 536 quinol dehydrogenase membrane component YP_670142.1 2336304 R 362663 CDS YP_670143.1 110642413 4191758 complement(2337154..2337849) 1 NC_008253.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2337849 napG 4191758 napG Escherichia coli 536 quinol dehydrogenase periplasmic component YP_670143.1 2337154 R 362663 CDS YP_670144.1 110642414 4191759 complement(2337856..2340342) 1 NC_008253.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2340342 4191759 ECP_2247 Escherichia coli 536 nitrate reductase catalytic subunit YP_670144.1 2337856 R 362663 CDS YP_670145.1 110642415 4191760 complement(2340339..2340602) 1 NC_008253.1 assembly protein for periplasmic nitrate reductase 2340602 4191760 ECP_2248 Escherichia coli 536 assembly protein for periplasmic nitrate reductase YP_670145.1 2340339 R 362663 CDS YP_670146.1 110642416 4191761 complement(2340592..2341086) 1 NC_008253.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA.; ferredoxin-type protein 2341086 4191761 ECP_2249 Escherichia coli 536 ferredoxin-type protein YP_670146.1 2340592 R 362663 CDS YP_670147.1 110642417 4190121 2341195..2341359 1 NC_008253.1 hypothetical protein 2341359 4190121 ECP_2250 Escherichia coli 536 hypothetical protein YP_670147.1 2341195 D 362663 CDS YP_670148.1 110642418 4190122 2341494..2341982 1 NC_008253.1 ecotin 2341982 4190122 ECP_2251 Escherichia coli 536 ecotin YP_670148.1 2341494 D 362663 CDS YP_670149.1 110642419 4190123 complement(2342132..2343760) 1 NC_008253.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2343760 4190123 ECP_2252 Escherichia coli 536 malate:quinone oxidoreductase YP_670149.1 2342132 R 362663 CDS YP_670150.1 110642420 4190124 complement(2343996..2344652) 1 NC_008253.1 similar to C-terminal part of ATP-binding protein YojI; ABC transporter 2344652 4190124 ECP_2253 Escherichia coli 536 ABC transporter YP_670150.1 2343996 R 362663 CDS YP_670151.1 110642421 4190125 complement(2344656..2345639) 1 NC_008253.1 similar to N-terminal part of ATP-binding protein YojI; ABC transporter 2345639 4190125 ECP_2254 Escherichia coli 536 ABC transporter YP_670151.1 2344656 R 362663 CDS YP_670152.1 110642422 4190126 complement(2345715..2346365) 1 NC_008253.1 alkylated DNA repair protein AlkB 2346365 4190126 ECP_2255 Escherichia coli 536 alkylated DNA repair protein AlkB YP_670152.1 2345715 R 362663 CDS YP_670153.1 110642423 4190127 complement(2346365..2347429) 1 NC_008253.1 ADA regulatory protein 2347429 4190127 ECP_2256 Escherichia coli 536 ADA regulatory protein YP_670153.1 2346365 R 362663 CDS YP_670154.1 110642424 4190128 complement(2347503..2348558) 1 NC_008253.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2348558 4190128 ECP_2257 Escherichia coli 536 thiamine biosynthesis lipoprotein ApbE YP_670154.1 2347503 R 362663 CDS YP_670155.1 110642425 4190129 complement(2348670..2349797) 1 NC_008253.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2349797 4190129 ECP_2258 Escherichia coli 536 outer membrane porin protein C YP_670155.1 2348670 R 362663 CDS YP_670156.1 110642426 4190130 2350536..2353208 1 NC_008253.1 phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2353208 4190130 ECP_2259 Escherichia coli 536 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_670156.1 2350536 D 362663 CDS YP_670157.1 110642427 4190131 2353225..2353875 1 NC_008253.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2353875 4190131 ECP_2260 Escherichia coli 536 transcriptional regulator RcsB YP_670157.1 2353225 D 362663 CDS YP_670158.1 110642428 4190132 complement(2354075..2356924) 1 NC_008253.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2356924 4190132 ECP_2261 Escherichia coli 536 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_670158.1 2354075 R 362663 CDS YP_670159.1 110642429 4190133 2357091..2358917 1 NC_008253.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2358917 4190133 ECP_2262 Escherichia coli 536 sensory histidine kinase AtoS YP_670159.1 2357091 D 362663 CDS YP_670160.1 110642430 4190134 2358914..2360299 1 NC_008253.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2360299 4190134 ECP_2263 Escherichia coli 536 acetoacetate metabolism regulatory protein AtoC YP_670160.1 2358914 D 362663 CDS YP_670161.1 110642431 4190137 2361158..2361808 1 NC_008253.1 acetate CoA-transferase subunit beta 2361808 4190137 ECP_2266 Escherichia coli 536 acetate CoA-transferase subunit beta YP_670161.1 2361158 D 362663 CDS YP_670162.1 110642432 4191916 2361805..2363127 1 NC_008253.1 short-chain fatty acids transporter 2363127 4191916 ECP_2267 Escherichia coli 536 short-chain fatty acids transporter YP_670162.1 2361805 D 362663 CDS YP_670163.1 110642433 4191917 2363158..2364342 1 NC_008253.1 acetyl-CoA acetyltransferase 2364342 4191917 ECP_2268 Escherichia coli 536 acetyl-CoA acetyltransferase YP_670163.1 2363158 D 362663 CDS YP_670164.1 110642434 4191918 complement(2364416..2365192) 1 NC_008253.1 hypothetical protein 2365192 4191918 ECP_2269 Escherichia coli 536 hypothetical protein YP_670164.1 2364416 R 362663 CDS YP_670165.1 110642435 4191919 complement(2365197..2366846) 1 NC_008253.1 hypothetical protein 2366846 4191919 ECP_2270 Escherichia coli 536 hypothetical protein YP_670165.1 2365197 R 362663 CDS YP_670166.1 110642436 4191920 complement(2366847..2371451) 1 NC_008253.1 hypothetical protein 2371451 4191920 ECP_2271 Escherichia coli 536 hypothetical protein YP_670166.1 2366847 R 362663 CDS YP_670167.1 110642437 4191921 complement(2371385..2372008) 1 NC_008253.1 hypothetical protein 2372008 4191921 ECP_2272 Escherichia coli 536 hypothetical protein YP_670167.1 2371385 R 362663 CDS YP_670168.1 110642438 4191922 complement(2372005..2373693) 1 NC_008253.1 hypothetical protein 2373693 4191922 ECP_2273 Escherichia coli 536 hypothetical protein YP_670168.1 2372005 R 362663 CDS YP_670169.1 110642439 4191923 complement(2373842..2376469) 1 NC_008253.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2376469 4191923 ECP_2274 Escherichia coli 536 DNA gyrase subunit A YP_670169.1 2373842 R 362663 CDS YP_670170.1 110642440 4191924 2376616..2377338 1 NC_008253.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2377338 4191924 ECP_2275 Escherichia coli 536 3-demethylubiquinone-9 3-methyltransferase YP_670170.1 2376616 D 362663 CDS YP_670171.1 110642441 4191925 complement(2377478..2381242) 1 NC_008253.1 adhesin 2381242 4191925 ECP_2276 Escherichia coli 536 adhesin YP_670171.1 2377478 R 362663 CDS YP_670172.1 110642442 4191926 2381918..2384203 1 NC_008253.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2384203 4191926 ECP_2277 Escherichia coli 536 ribonucleotide-diphosphate reductase subunit alpha YP_670172.1 2381918 D 362663 CDS YP_670173.1 110642443 4191927 2384393..2385523 1 NC_008253.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2385523 nrdB 4191927 nrdB Escherichia coli 536 ribonucleotide-diphosphate reductase subunit beta YP_670173.1 2384393 D 362663 CDS YP_670174.1 110642444 4191928 2385523..2385777 1 NC_008253.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2385777 4191928 ECP_2279 Escherichia coli 536 2Fe-2S ferredoxin YP_670174.1 2385523 D 362663 CDS YP_670175.1 110642445 4191929 complement(2385831..2386481) 1 NC_008253.1 PH-inducible protein involved in stress response; hypothetical protein 2386481 4191929 ECP_2280 Escherichia coli 536 hypothetical protein YP_670175.1 2385831 R 362663 CDS YP_670176.1 110642446 4191930 complement(2386684..2387691) 1 NC_008253.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2387691 glpQ 4191930 glpQ Escherichia coli 536 glycerophosphodiester phosphodiesterase YP_670176.1 2386684 R 362663 CDS YP_670177.1 110642447 4191931 complement(2387765..2389123) 1 NC_008253.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2389123 glpT 4191931 glpT Escherichia coli 536 sn-glycerol-3-phosphate transporter YP_670177.1 2387765 R 362663 CDS YP_670178.1 110642448 4191932 2389396..2391024 1 NC_008253.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2391024 glpA 4191932 glpA Escherichia coli 536 sn-glycerol-3-phosphate dehydrogenase subunit A YP_670178.1 2389396 D 362663 CDS YP_670179.1 110642449 4191933 2391014..2392195 1 NC_008253.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2392195 4191933 ECP_2284 Escherichia coli 536 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_670179.1 2391014 D 362663 CDS YP_670180.1 110642450 4191934 2392270..2393460 1 NC_008253.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2393460 glpC 4191934 glpC Escherichia coli 536 sn-glycerol-3-phosphate dehydrogenase subunit C YP_670180.1 2392270 D 362663 CDS YP_670181.1 110642451 4191935 2393653..2394612 1 NC_008253.1 hypothetical protein 2394612 4191935 ECP_2286 Escherichia coli 536 hypothetical protein YP_670181.1 2393653 D 362663 CDS YP_670182.1 110642452 4190334 2394625..2394810 1 NC_008253.1 hypothetical protein 2394810 4190334 ECP_2287 Escherichia coli 536 hypothetical protein YP_670182.1 2394625 D 362663 CDS YP_670183.1 110642453 4190335 complement(2394851..2395654) 1 NC_008253.1 aldolase 2395654 4190335 ECP_2288 Escherichia coli 536 aldolase YP_670183.1 2394851 R 362663 CDS YP_670184.1 110642454 4190336 complement(2395672..2396961) 1 NC_008253.1 transmembrane transporter YfaV 2396961 4190336 ECP_2289 Escherichia coli 536 transmembrane transporter YfaV YP_670184.1 2395672 R 362663 CDS YP_670185.1 110642455 4190337 complement(2397018..2398235) 1 NC_008253.1 hypothetical protein 2398235 4190337 ECP_2290 Escherichia coli 536 hypothetical protein YP_670185.1 2397018 R 362663 CDS YP_670186.1 110642456 4190338 complement(2398238..2399020) 1 NC_008253.1 transcriptional regulator YfaX 2399020 4190338 ECP_2291 Escherichia coli 536 transcriptional regulator YfaX YP_670186.1 2398238 R 362663 CDS YP_670187.1 110642457 4190339 complement(2399240..2400442) 1 NC_008253.1 competence damage-inducible protein A 2400442 4190339 ECP_2292 Escherichia coli 536 competence damage-inducible protein A YP_670187.1 2399240 R 362663 CDS YP_670188.1 110642458 4190340 complement(2400542..2401084) 1 NC_008253.1 hypothetical protein 2401084 4190340 ECP_2293 Escherichia coli 536 hypothetical protein YP_670188.1 2400542 R 362663 CDS YP_670189.1 110642459 4190341 2401364..2401789 1 NC_008253.1 nudix hydrolase YfaO 2401789 4190341 ECP_2294 Escherichia coli 536 nudix hydrolase YfaO YP_670189.1 2401364 D 362663 CDS YP_670190.1 110642460 4190342 complement(2401828..2402430) 1 NC_008253.1 aluminum resistance protein 2402430 4190342 ECP_2295 Escherichia coli 536 aluminum resistance protein YP_670190.1 2401828 R 362663 CDS YP_670191.1 110642461 4190343 2402720..2403877 1 NC_008253.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2403877 4190343 ECP_2296 Escherichia coli 536 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_670191.1 2402720 D 362663 CDS YP_670192.1 110642462 4190344 2403881..2404849 1 NC_008253.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2404849 4190344 ECP_2297 Escherichia coli 536 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_670192.1 2403881 D 362663 CDS YP_670193.1 110642463 4190345 2404849..2406831 1 NC_008253.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2406831 4190345 ECP_2298 Escherichia coli 536 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_670193.1 2404849 D 362663 CDS YP_670194.1 110642464 4190346 2406828..2407718 1 NC_008253.1 hypothetical protein 2407718 4190346 ECP_2299 Escherichia coli 536 hypothetical protein YP_670194.1 2406828 D 362663 CDS YP_670195.1 110642465 4190347 2407718..2409370 1 NC_008253.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2409370 arnT 4190347 arnT Escherichia coli 536 4-amino-4-deoxy-L-arabinose transferase YP_670195.1 2407718 D 362663 CDS YP_670196.1 110642466 4190348 2409367..2409702 1 NC_008253.1 hypothetical protein 2409702 4190348 ECP_2301 Escherichia coli 536 hypothetical protein YP_670196.1 2409367 D 362663 CDS YP_670197.1 110642467 4190349 2409702..2410088 1 NC_008253.1 hypothetical protein 2410088 4190349 ECP_2302 Escherichia coli 536 hypothetical protein YP_670197.1 2409702 D 362663 CDS YP_670198.1 110642468 4190350 complement(2410082..2410348) 1 NC_008253.1 polymyxin B resistance protein pmrD 2410348 4190350 ECP_2303 Escherichia coli 536 polymyxin B resistance protein pmrD YP_670198.1 2410082 R 362663 CDS YP_670199.1 110642469 4190351 complement(2410458..2411813) 1 NC_008253.1 O-succinylbenzoic acid--CoA ligase 2411813 4190351 ECP_2304 Escherichia coli 536 O-succinylbenzoic acid--CoA ligase YP_670199.1 2410458 R 362663 CDS YP_670200.1 110642470 4190352 complement(2411810..2412772) 1 NC_008253.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2412772 4190352 ECP_2305 Escherichia coli 536 O-succinylbenzoate synthase YP_670200.1 2411810 R 362663 CDS YP_670201.1 110642471 4191442 complement(2412772..2413629) 1 NC_008253.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2413629 4191442 ECP_2306 Escherichia coli 536 naphthoate synthase YP_670201.1 2412772 R 362663 CDS YP_670202.1 110642472 4191443 complement(2413644..2414402) 1 NC_008253.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 2414402 4191443 ECP_2307 Escherichia coli 536 acyl-CoA thioester hydrolase YP_670202.1 2413644 R 362663 CDS YP_670203.1 110642473 4191444 complement(2414399..2416258) 1 NC_008253.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2416258 4191444 ECP_2308 Escherichia coli 536 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_670203.1 2414399 R 362663 CDS YP_670204.1 110642474 4191445 complement(2416158..2417453) 1 NC_008253.1 menaquinone-specific isochorismate synthase 2417453 4191445 ECP_2309 Escherichia coli 536 menaquinone-specific isochorismate synthase YP_670204.1 2416158 R 362663 CDS YP_670205.1 110642475 4191446 complement(2417532..2417837) 1 NC_008253.1 hypothetical protein 2417837 4191446 ECP_2310 Escherichia coli 536 hypothetical protein YP_670205.1 2417532 R 362663 CDS YP_670206.1 110642476 4191447 complement(2417892..2418353) 1 NC_008253.1 hypothetical protein 2418353 4191447 ECP_2311 Escherichia coli 536 hypothetical protein YP_670206.1 2417892 R 362663 CDS YP_670207.1 110642477 4191448 2418418..2419335 1 NC_008253.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2419335 4191448 ECP_2312 Escherichia coli 536 ribonuclease Z YP_670207.1 2418418 D 362663 CDS YP_670208.1 110642478 4191449 2419691..2420662 1 NC_008253.1 hypothetical protein 2420662 4191449 ECP_2313 Escherichia coli 536 hypothetical protein YP_670208.1 2419691 D 362663 CDS YP_670209.1 110642479 4191450 2420765..2421268 1 NC_008253.1 hypothetical protein 2421268 4191450 ECP_2314 Escherichia coli 536 hypothetical protein YP_670209.1 2420765 D 362663 CDS YP_670210.1 110642480 4191451 complement(2421335..2422792) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2422792 4191451 ECP_2315 Escherichia coli 536 NADH dehydrogenase subunit N YP_670210.1 2421335 R 362663 CDS YP_670211.1 110642481 4191452 complement(2422799..2424328) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2424328 4191452 ECP_2316 Escherichia coli 536 NADH dehydrogenase subunit M YP_670211.1 2422799 R 362663 CDS YP_670212.1 110642482 4191453 complement(2424492..2426333) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2426333 4191453 ECP_2317 Escherichia coli 536 NADH dehydrogenase subunit L YP_670212.1 2424492 R 362663 CDS YP_670213.1 110642483 4191454 complement(2426330..2426632) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2426632 4191454 ECP_2318 Escherichia coli 536 NADH dehydrogenase subunit K YP_670213.1 2426330 R 362663 CDS YP_670214.1 110642484 4191455 complement(2426629..2427183) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2427183 4191455 ECP_2319 Escherichia coli 536 NADH dehydrogenase subunit J YP_670214.1 2426629 R 362663 CDS YP_670215.1 110642485 4191456 complement(2427195..2427737) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2427737 4191456 ECP_2320 Escherichia coli 536 NADH dehydrogenase subunit I YP_670215.1 2427195 R 362663 CDS YP_670216.1 110642486 4191457 complement(2427752..2428729) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2428729 4191457 ECP_2321 Escherichia coli 536 NADH dehydrogenase subunit H YP_670216.1 2427752 R 362663 CDS YP_670217.1 110642487 4191458 complement(2428726..2431458) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2431458 4191458 ECP_2322 Escherichia coli 536 NADH dehydrogenase subunit G YP_670217.1 2428726 R 362663 CDS YP_670218.1 110642488 4191459 complement(2431505..2432842) 1 NC_008253.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2432842 4191459 ECP_2323 Escherichia coli 536 NADH dehydrogenase I subunit F YP_670218.1 2431505 R 362663 CDS YP_670219.1 110642489 4191460 complement(2432839..2433339) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2433339 4191460 ECP_2324 Escherichia coli 536 NADH dehydrogenase subunit E YP_670219.1 2432839 R 362663 CDS YP_670220.1 110642490 4191461 complement(2433342..2435132) 1 NC_008253.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2435132 4191461 ECP_2325 Escherichia coli 536 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_670220.1 2433342 R 362663 CDS YP_670221.1 110642491 4189352 complement(2435238..2435900) 1 NC_008253.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2435900 4189352 ECP_2326 Escherichia coli 536 NADH dehydrogenase subunit B YP_670221.1 2435238 R 362663 CDS YP_670222.1 110642492 4189353 complement(2435916..2436359) 1 NC_008253.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2436359 4189353 ECP_2327 Escherichia coli 536 NADH dehydrogenase subunit A YP_670222.1 2435916 R 362663 CDS YP_670223.1 110642493 4189354 complement(2436989..2437927) 1 NC_008253.1 transcriptional regulator lrhA 2437927 4189354 ECP_2328 Escherichia coli 536 transcriptional regulator lrhA YP_670223.1 2436989 R 362663 CDS YP_670224.1 110642494 4189355 2438847..2440064 1 NC_008253.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2440064 4189355 ECP_2329 Escherichia coli 536 aminotransferase YP_670224.1 2438847 D 362663 CDS YP_670225.1 110642495 4189356 2440148..2440747 1 NC_008253.1 hypothetical protein 2440747 4189356 ECP_2330 Escherichia coli 536 hypothetical protein YP_670225.1 2440148 D 362663 CDS YP_670226.1 110642496 4189357 complement(2440806..2442638) 1 NC_008253.1 hypothetical protein 2442638 4189357 ECP_2331 Escherichia coli 536 hypothetical protein YP_670226.1 2440806 R 362663 CDS YP_670227.1 110642497 4189358 complement(2442725..2443375) 1 NC_008253.1 phosphatase 2443375 4189358 ECP_2332 Escherichia coli 536 phosphatase YP_670227.1 2442725 R 362663 CDS YP_670228.1 110642498 4189359 complement(2443386..2443880) 1 NC_008253.1 hypothetical protein 2443880 4189359 ECP_2333 Escherichia coli 536 hypothetical protein YP_670228.1 2443386 R 362663 CDS YP_670229.1 110642499 4189360 complement(2443963..2444418) 1 NC_008253.1 hypothetical protein 2444418 4189360 ECP_2334 Escherichia coli 536 hypothetical protein YP_670229.1 2443963 R 362663 CDS YP_670230.1 110642500 4189361 2444756..2445958 1 NC_008253.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2445958 4189361 ECP_2335 Escherichia coli 536 acetate kinase YP_670230.1 2444756 D 362663 CDS YP_670231.1 110642501 4189362 2446033..2448177 1 NC_008253.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2448177 4189362 ECP_2336 Escherichia coli 536 phosphate acetyltransferase YP_670231.1 2446033 D 362663 CDS YP_670232.1 110642502 4189363 2448367..2449887 1 NC_008253.1 hypothetical protein 2449887 4189363 ECP_2337 Escherichia coli 536 hypothetical protein YP_670232.1 2448367 D 362663 CDS YP_670233.1 110642503 4189364 complement(2449921..2450463) 1 NC_008253.1 hypothetical protein 2450463 4189364 ECP_2338 Escherichia coli 536 hypothetical protein YP_670233.1 2449921 R 362663 CDS YP_670234.1 110642504 4189365 complement(2450521..2451072) 1 NC_008253.1 phosphodiesterase 2451072 4189365 ECP_2339 Escherichia coli 536 phosphodiesterase YP_670234.1 2450521 R 362663 CDS YP_670235.1 110642505 4189366 complement(2451128..2451772) 1 NC_008253.1 GST-like protein 2451772 4189366 ECP_2340 Escherichia coli 536 GST-like protein YP_670235.1 2451128 R 362663 CDS YP_670236.1 110642506 4189367 2451908..2452555 1 NC_008253.1 glutathione S-transferase 2452555 4189367 ECP_2341 Escherichia coli 536 glutathione S-transferase YP_670236.1 2451908 D 362663 CDS YP_670237.1 110642507 4189368 2452612..2452974 1 NC_008253.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2452974 folX 4189368 folX Escherichia coli 536 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_670237.1 2452612 D 362663 CDS YP_670238.1 110642508 4189369 2452995..2453888 1 NC_008253.1 hypothetical protein 2453888 4189369 ECP_2343 Escherichia coli 536 hypothetical protein YP_670238.1 2452995 D 362663 CDS YP_670239.1 110642509 4189370 complement(2453936..2454826) 1 NC_008253.1 hypothetical protein 2454826 4189370 ECP_2344 Escherichia coli 536 hypothetical protein YP_670239.1 2453936 R 362663 CDS YP_670240.1 110642510 4191189 complement(2455022..2455795) 1 NC_008253.1 histidine/lysine/arginine/ornithine transporter subunit 2455795 4191189 ECP_2345 Escherichia coli 536 histidine/lysine/arginine/ornithine transporter subunit YP_670240.1 2455022 R 362663 CDS YP_670241.1 110642511 4191190 complement(2455803..2456519) 1 NC_008253.1 histidine transport system permease HisM 2456519 4191190 ECP_2346 Escherichia coli 536 histidine transport system permease HisM YP_670241.1 2455803 R 362663 CDS YP_670242.1 110642512 4191191 complement(2456556..2457203) 1 NC_008253.1 histidine transport system permease HisQ 2457203 4191191 ECP_2347 Escherichia coli 536 histidine transport system permease HisQ YP_670242.1 2456556 R 362663 CDS YP_670243.1 110642513 4191192 complement(2457293..2458075) 1 NC_008253.1 histidine-binding periplasmic protein 2458075 4191192 ECP_2348 Escherichia coli 536 histidine-binding periplasmic protein YP_670243.1 2457293 R 362663 CDS YP_670244.1 110642514 4191193 complement(2458296..2459078) 1 NC_008253.1 lysine-arginine-ornithine-binding periplasmic protein 2459078 4191193 ECP_2349 Escherichia coli 536 lysine-arginine-ornithine-binding periplasmic protein YP_670244.1 2458296 R 362663 CDS YP_670245.1 110642515 4191194 complement(2459344..2459913) 1 NC_008253.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2459913 4191194 ECP_2350 Escherichia coli 536 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_670245.1 2459344 R 362663 CDS YP_670246.1 110642516 4191195 complement(2460008..2461525) 1 NC_008253.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2461525 4191195 ECP_2351 Escherichia coli 536 amidophosphoribosyltransferase YP_670246.1 2460008 R 362663 CDS YP_670247.1 110642517 4191196 complement(2461562..2462050) 1 NC_008253.1 membrane protein required for colicin V production; colicin V production protein 2462050 4191196 ECP_2352 Escherichia coli 536 colicin V production protein YP_670247.1 2461562 R 362663 CDS YP_670248.1 110642518 4191197 complement(2462855..2463517) 1 NC_008253.1 hypothetical protein 2463517 4191197 ECP_2353 Escherichia coli 536 hypothetical protein YP_670248.1 2462855 R 362663 CDS YP_670249.1 110642519 4191198 complement(2463507..2464775) 1 NC_008253.1 bifunctional; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2464775 4191198 ECP_2354 Escherichia coli 536 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_670249.1 2463507 R 362663 CDS YP_670250.1 110642520 4191199 complement(2464845..2465759) 1 NC_008253.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2465759 4191199 ECP_2355 Escherichia coli 536 acetyl-CoA carboxylase subunit beta YP_670250.1 2464845 R 362663 CDS YP_670251.1 110642521 4191200 complement(2465915..2466574) 1 NC_008253.1 hypothetical protein 2466574 4191200 ECP_2356 Escherichia coli 536 hypothetical protein YP_670251.1 2465915 R 362663 CDS YP_670252.1 110642522 4191201 complement(2466657..2467469) 1 NC_008253.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2467469 truA 4191201 truA Escherichia coli 536 tRNA pseudouridine synthase A YP_670252.1 2466657 R 362663 CDS YP_670253.1 110642523 4191202 complement(2467469..2468482) 1 NC_008253.1 semialdehyde dehydrogenase 2468482 4191202 ECP_2358 Escherichia coli 536 semialdehyde dehydrogenase YP_670253.1 2467469 R 362663 CDS YP_670254.1 110642524 4191203 complement(2468548..2469684) 1 NC_008253.1 erythronate-4-phosphate dehydrogenase 2469684 4191203 ECP_2359 Escherichia coli 536 erythronate-4-phosphate dehydrogenase YP_670254.1 2468548 R 362663 CDS YP_670255.1 110642525 4191204 2469783..2470778 1 NC_008253.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2470778 flk 4191204 flk Escherichia coli 536 flagella biosynthesis regulator YP_670255.1 2469783 D 362663 CDS YP_670256.1 110642526 4191205 complement(2470775..2471953) 1 NC_008253.1 hypothetical protein 2471953 4191205 ECP_2361 Escherichia coli 536 hypothetical protein YP_670256.1 2470775 R 362663 CDS YP_670257.1 110642527 4191206 complement(2472218..2473438) 1 NC_008253.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2473438 4191206 ECP_2362 Escherichia coli 536 3-oxoacyl-ACP synthase YP_670257.1 2472218 R 362663 CDS YP_670258.1 110642528 4191207 2473597..2475603 1 NC_008253.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2475603 mnmC 4191207 mnmC Escherichia coli 536 5-methylaminomethyl-2-thiouridine methyltransferase YP_670258.1 2473597 D 362663 CDS YP_670259.1 110642529 4191208 complement(2475724..2476002) 1 NC_008253.1 hypothetical protein 2476002 4191208 ECP_2364 Escherichia coli 536 hypothetical protein YP_670259.1 2475724 R 362663 CDS YP_670260.1 110642530 4188697 complement(2476036..2476584) 1 NC_008253.1 hypothetical protein 2476584 4188697 ECP_2365 Escherichia coli 536 hypothetical protein YP_670260.1 2476036 R 362663 CDS YP_670261.1 110642531 4188698 complement(2476584..2477393) 1 NC_008253.1 hypothetical protein 2477393 4188698 ECP_2366 Escherichia coli 536 hypothetical protein YP_670261.1 2476584 R 362663 CDS YP_670262.1 110642532 4188699 complement(2477393..2478217) 1 NC_008253.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2478217 mepA 4188699 mepA Escherichia coli 536 penicillin-insensitive murein endopeptidase YP_670262.1 2477393 R 362663 CDS YP_670263.1 110642533 4188700 complement(2478221..2479306) 1 NC_008253.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2479306 4188700 ECP_2368 Escherichia coli 536 chorismate synthase YP_670263.1 2478221 R 362663 CDS YP_670264.1 110642534 4188701 complement(2479341..2480606) 1 NC_008253.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2480606 4188701 ECP_2369 Escherichia coli 536 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_670264.1 2479341 R 362663 CDS YP_670265.1 110642535 4188702 2480439..2480990 1 NC_008253.1 hypothetical protein 2480990 4188702 ECP_2370 Escherichia coli 536 hypothetical protein YP_670265.1 2480439 D 362663 CDS YP_670266.1 110642536 4188703 complement(2481407..2482168) 1 NC_008253.1 hypothetical protein 2482168 4188703 ECP_2371 Escherichia coli 536 hypothetical protein YP_670266.1 2481407 R 362663 CDS YP_670267.1 110642537 4188704 complement(2482170..2482697) 1 NC_008253.1 fimbrial-like protein YfcP 2482697 4188704 ECP_2372 Escherichia coli 536 fimbrial-like protein YfcP YP_670267.1 2482170 R 362663 CDS YP_670268.1 110642538 4188705 complement(2482694..2483173) 1 NC_008253.1 fimbrial-like protein YfcQ 2483173 4188705 ECP_2373 Escherichia coli 536 fimbrial-like protein YfcQ YP_670268.1 2482694 R 362663 CDS YP_670269.1 110642539 4188706 complement(2483170..2483673) 1 NC_008253.1 hypothetical protein 2483673 4188706 ECP_2374 Escherichia coli 536 hypothetical protein YP_670269.1 2483170 R 362663 CDS YP_670270.1 110642540 4188707 complement(2483690..2484442) 1 NC_008253.1 fimbrial chaperone 2484442 4188707 ECP_2375 Escherichia coli 536 fimbrial chaperone YP_670270.1 2483690 R 362663 CDS YP_670271.1 110642541 4188708 complement(2484462..2487116) 1 NC_008253.1 outer membrane usher protein YfcU 2487116 4188708 ECP_2376 Escherichia coli 536 outer membrane usher protein YfcU YP_670271.1 2484462 R 362663 CDS YP_670272.1 110642542 4188709 complement(2487191..2487757) 1 NC_008253.1 fimbrial-like protein YfcV 2487757 4188709 ECP_2377 Escherichia coli 536 fimbrial-like protein YfcV YP_670272.1 2487191 R 362663 CDS YP_670273.1 110642543 4188710 complement(2488324..2488809) 1 NC_008253.1 phosphohistidine phosphatase 2488809 4188710 ECP_2378 Escherichia coli 536 phosphohistidine phosphatase YP_670273.1 2488324 R 362663 CDS YP_670274.1 110642544 4188711 complement(2489012..2491156) 1 NC_008253.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2491156 fadJ 4188711 fadJ Escherichia coli 536 multifunctional fatty acid oxidation complex subunit alpha YP_670274.1 2489012 R 362663 CDS YP_670275.1 110642545 4188712 complement(2491156..2492466) 1 NC_008253.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2492466 fadI 4188712 fadI Escherichia coli 536 3-ketoacyl-CoA thiolase YP_670275.1 2491156 R 362663 CDS YP_670276.1 110642546 4188713 complement(2492646..2492930) 1 NC_008253.1 hypothetical protein 2492930 4188713 ECP_2381 Escherichia coli 536 hypothetical protein YP_670276.1 2492646 R 362663 CDS YP_670277.1 110642547 4188714 2493302..2494642 1 NC_008253.1 long-chain fatty acid outer membrane transporter 2494642 4188714 ECP_2382 Escherichia coli 536 long-chain fatty acid outer membrane transporter YP_670277.1 2493302 D 362663 CDS YP_670278.1 110642548 4188715 complement(2494704..2495459) 1 NC_008253.1 VacJ lipoprotein precursor 2495459 4188715 ECP_2383 Escherichia coli 536 VacJ lipoprotein precursor YP_670278.1 2494704 R 362663 CDS YP_670279.1 110642549 4189621 2495753..2496685 1 NC_008253.1 transporter protein 2496685 4189621 ECP_2384 Escherichia coli 536 transporter protein YP_670279.1 2495753 D 362663 CDS YP_670280.1 110642550 4189623 complement(2497286..2498533) 1 NC_008253.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 2498533 lacY 4189623 lacY Escherichia coli 536 galactoside permease YP_670280.1 2497286 R 362663 CDS YP_670281.1 110642551 4189624 complement(2498602..2499519) 1 NC_008253.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2499519 4189624 ECP_2387 Escherichia coli 536 aminoimidazole riboside kinase YP_670281.1 2498602 R 362663 CDS YP_670282.1 110642552 4189625 2499735..2501168 1 NC_008253.1 sucrose-6-phosphate hydrolase 2501168 4189625 ECP_2388 Escherichia coli 536 sucrose-6-phosphate hydrolase YP_670282.1 2499735 D 362663 CDS YP_670283.1 110642553 4189626 complement(2501176..2502171) 1 NC_008253.1 sucrose operon repressor 2502171 4189626 ECP_2389 Escherichia coli 536 sucrose operon repressor YP_670283.1 2501176 R 362663 CDS YP_670284.1 110642554 4189627 2502401..2502619 1 NC_008253.1 hypothetical protein 2502619 4189627 ECP_2390 Escherichia coli 536 hypothetical protein YP_670284.1 2502401 D 362663 CDS YP_670285.1 110642555 4189628 2502637..2503965 1 NC_008253.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2503965 4189628 ECP_2391 Escherichia coli 536 D-serine dehydratase YP_670285.1 2502637 D 362663 CDS YP_670286.1 110642556 4189629 complement(2504073..2505611) 1 NC_008253.1 multidrug resistance protein Y 2505611 4189629 ECP_2392 Escherichia coli 536 multidrug resistance protein Y YP_670286.1 2504073 R 362663 CDS YP_670287.1 110642557 4189630 complement(2505611..2506651) 1 NC_008253.1 multidrug resistance protein K 2506651 4189630 ECP_2393 Escherichia coli 536 multidrug resistance protein K YP_670287.1 2505611 R 362663 CDS YP_670288.1 110642558 4189631 2507190..2507804 1 NC_008253.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2507804 4189631 ECP_2394 Escherichia coli 536 DNA-binding transcriptional activator EvgA YP_670288.1 2507190 D 362663 CDS YP_670289.1 110642559 4189632 2507809..2511402 1 NC_008253.1 hybrid sensory histidine kinase in two-component regulatory system with EvgA 2511402 4189632 ECP_2395 Escherichia coli 536 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_670289.1 2507809 D 362663 CDS YP_670290.1 110642560 4189633 complement(2511458..2512603) 1 NC_008253.1 hypothetical protein 2512603 4189633 ECP_2396 Escherichia coli 536 hypothetical protein YP_670290.1 2511458 R 362663 CDS YP_670291.1 110642561 4189634 complement(2512677..2513621) 1 NC_008253.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 2513621 4189634 ECP_2397 Escherichia coli 536 transporter YfdV YP_670291.1 2512677 R 362663 CDS YP_670292.1 110642562 4189635 complement(2513691..2515385) 1 NC_008253.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 2515385 4189635 ECP_2398 Escherichia coli 536 oxalyl-CoA decarboxylase YP_670292.1 2513691 R 362663 CDS YP_670293.1 110642563 4189636 complement(2515439..2516689) 1 NC_008253.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2516689 4189636 ECP_2399 Escherichia coli 536 formyl-coenzyme A transferase YP_670293.1 2515439 R 362663 CDS YP_670294.1 110642564 4189637 complement(2517201..2517668) 1 NC_008253.1 hypothetical protein 2517668 4189637 ECP_2400 Escherichia coli 536 hypothetical protein YP_670294.1 2517201 R 362663 CDS YP_670295.1 110642565 4189638 2517891..2518052 1 NC_008253.1 hypothetical protein 2518052 4189638 ECP_2401 Escherichia coli 536 hypothetical protein YP_670295.1 2517891 D 362663 CDS YP_670296.1 110642566 4189639 2518126..2518401 1 NC_008253.1 lipoprotein YpdI 2518401 4189639 ECP_2402 Escherichia coli 536 lipoprotein YpdI YP_670296.1 2518126 D 362663 CDS YP_670297.1 110642567 4189926 complement(2518478..2518720) 1 NC_008253.1 hypothetical protein 2518720 4189926 ECP_2403 Escherichia coli 536 hypothetical protein YP_670297.1 2518478 R 362663 CDS YP_670298.1 110642568 4189927 2519073..2519993 1 NC_008253.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2519993 4189927 ECP_2404 Escherichia coli 536 lipid A biosynthesis palmitoleoyl acyltransferase YP_670298.1 2519073 D 362663 CDS YP_670299.1 110642569 4189928 complement(2520485..2521723) 1 NC_008253.1 aminotransferase 2521723 4189928 ECP_2405 Escherichia coli 536 aminotransferase YP_670299.1 2520485 R 362663 CDS YP_670300.1 110642570 4189929 2522118..2523797 1 NC_008253.1 hypothetical protein 2523797 4189929 ECP_2406 Escherichia coli 536 hypothetical protein YP_670300.1 2522118 D 362663 CDS YP_670301.1 110642571 4189930 2523812..2524546 1 NC_008253.1 hypothetical protein 2524546 4189930 ECP_2407 Escherichia coli 536 hypothetical protein YP_670301.1 2523812 D 362663 CDS YP_670302.1 110642572 4189931 2524559..2525416 1 NC_008253.1 transcriptional regulator YpdC 2525416 4189931 ECP_2408 Escherichia coli 536 transcriptional regulator YpdC YP_670302.1 2524559 D 362663 CDS YP_670303.1 110642573 4189932 complement(2525419..2527914) 1 NC_008253.1 phosphoenolpyruvate-protein phosphotransferase YpdD 2527914 4189932 ECP_2409 Escherichia coli 536 phosphoenolpyruvate-protein phosphotransferase YpdD YP_670303.1 2525419 R 362663 CDS YP_670304.1 110642574 4189933 complement(2527939..2528976) 1 NC_008253.1 metalloprotein; exoaminopeptidase 2528976 4189933 ECP_2410 Escherichia coli 536 exoaminopeptidase YP_670304.1 2527939 R 362663 CDS YP_670305.1 110642575 4189934 complement(2528976..2530061) 1 NC_008253.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2530061 4189934 ECP_2411 Escherichia coli 536 aminopeptidase YP_670305.1 2528976 R 362663 CDS YP_670306.1 110642576 4189935 complement(2530077..2531324) 1 NC_008253.1 PTS system IIC component YpdG 2531324 4189935 ECP_2412 Escherichia coli 536 PTS system IIC component YpdG YP_670306.1 2530077 R 362663 CDS YP_670307.1 110642577 4189936 complement(2531346..2531672) 1 NC_008253.1 PTS system IIB component YpdH 2531672 4189936 ECP_2413 Escherichia coli 536 PTS system IIB component YpdH YP_670307.1 2531346 R 362663 CDS YP_670308.1 110642578 4189937 complement(2531891..2532856) 1 NC_008253.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2532856 glk 4189937 glk Escherichia coli 536 glucokinase YP_670308.1 2531891 R 362663 CDS YP_670309.1 110642579 4189938 2533060..2534316 1 NC_008253.1 hypothetical protein 2534316 4189938 ECP_2415 Escherichia coli 536 hypothetical protein YP_670309.1 2533060 D 362663 CDS YP_670310.1 110642580 4189939 2534431..2534757 1 NC_008253.1 hypothetical protein 2534757 4189939 ECP_2416 Escherichia coli 536 hypothetical protein YP_670310.1 2534431 D 362663 CDS YP_670311.1 110642581 4189940 complement(2534898..2536136) 1 NC_008253.1 manganese transport protein MntH 2536136 4189940 ECP_2417 Escherichia coli 536 manganese transport protein MntH YP_670311.1 2534898 R 362663 CDS YP_670312.1 110642582 4189941 2536472..2537674 1 NC_008253.1 nucleoside permease NupC 2537674 4189941 ECP_2418 Escherichia coli 536 nucleoside permease NupC YP_670312.1 2536472 D 362663 CDS YP_670313.1 110642583 4189942 complement(2537724..2539973) 1 NC_008253.1 hypothetical protein 2539973 4189942 ECP_2419 Escherichia coli 536 hypothetical protein YP_670313.1 2537724 R 362663 CDS YP_670314.1 110642584 4189943 2540531..2540890 1 NC_008253.1 hypothetical protein 2540890 4189943 ECP_2420 Escherichia coli 536 hypothetical protein YP_670314.1 2540531 D 362663 CDS YP_670315.1 110642585 4189944 2540892..2541284 1 NC_008253.1 hypothetical protein 2541284 4189944 ECP_2421 Escherichia coli 536 hypothetical protein YP_670315.1 2540892 D 362663 CDS YP_670316.1 110642586 4191540 complement(2541335..2542750) 1 NC_008253.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2542750 gltX 4191540 gltX Escherichia coli 536 glutamyl-tRNA synthetase YP_670316.1 2541335 R 362663 CDS YP_670317.1 110642587 4191545 complement(2543517..2544401) 1 NC_008253.1 DNA-binding transcriptional activator XapR 2544401 4191545 ECP_2427 Escherichia coli 536 DNA-binding transcriptional activator XapR YP_670317.1 2543517 R 362663 CDS YP_670318.1 110642588 4191546 complement(2544442..2544600) 1 NC_008253.1 hypothetical protein 2544600 4191546 ECP_2428 Escherichia coli 536 hypothetical protein YP_670318.1 2544442 R 362663 CDS YP_670319.1 110642589 4191547 complement(2544653..2545909) 1 NC_008253.1 xanthosine permease 2545909 4191547 ECP_2429 Escherichia coli 536 xanthosine permease YP_670319.1 2544653 R 362663 CDS YP_670320.1 110642590 4191548 complement(2545970..2546803) 1 NC_008253.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2546803 4191548 ECP_2430 Escherichia coli 536 purine nucleoside phosphorylase YP_670320.1 2545970 R 362663 CDS YP_670321.1 110642591 4191549 2547051..2547815 1 NC_008253.1 hypothetical protein 2547815 4191549 ECP_2431 Escherichia coli 536 hypothetical protein YP_670321.1 2547051 D 362663 CDS YP_670322.1 110642592 4191550 complement(2547854..2548780) 1 NC_008253.1 LysR family transcriptional regulator 2548780 4191550 ECP_2432 Escherichia coli 536 LysR family transcriptional regulator YP_670322.1 2547854 R 362663 CDS YP_670323.1 110642593 4191551 2548870..2549868 1 NC_008253.1 hypothetical protein 2549868 4191551 ECP_2433 Escherichia coli 536 hypothetical protein YP_670323.1 2548870 D 362663 CDS YP_670324.1 110642594 4191552 complement(2549865..2550083) 1 NC_008253.1 hypothetical protein 2550083 4191552 ECP_2434 Escherichia coli 536 hypothetical protein YP_670324.1 2549865 R 362663 CDS YP_670325.1 110642595 4191553 complement(2550085..2552100) 1 NC_008253.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2552100 ligA 4191553 ligA Escherichia coli 536 NAD-dependent DNA ligase LigA YP_670325.1 2550085 R 362663 CDS YP_670326.1 110642596 4191554 complement(2552171..2553169) 1 NC_008253.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2553169 4191554 ECP_2436 Escherichia coli 536 cell division protein ZipA YP_670326.1 2552171 R 362663 CDS YP_670327.1 110642597 4188511 2553399..2554160 1 NC_008253.1 role in sulfur assimilation; sulfate transport protein CysZ 2554160 4188511 ECP_2437 Escherichia coli 536 sulfate transport protein CysZ YP_670327.1 2553399 D 362663 CDS YP_670328.1 110642598 4188512 2554345..2555316 1 NC_008253.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2555316 4188512 ECP_2438 Escherichia coli 536 cysteine synthase A YP_670328.1 2554345 D 362663 CDS YP_670329.1 110642599 4188513 2555700..2555957 1 NC_008253.1 phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) 2555957 4188513 ECP_2439 Escherichia coli 536 phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) YP_670329.1 2555700 D 362663 CDS YP_670330.1 110642600 4188514 2556002..2557729 1 NC_008253.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2557729 4188514 ECP_2440 Escherichia coli 536 phosphoenolpyruvate-protein phosphotransferase YP_670330.1 2556002 D 362663 CDS YP_670331.1 110642601 4188515 2557770..2558279 1 NC_008253.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; glucose-specific PTS system component 2558279 4188515 ECP_2441 Escherichia coli 536 glucose-specific PTS system component YP_670331.1 2557770 D 362663 CDS YP_670332.1 110642602 4188516 complement(2558322..2559173) 1 NC_008253.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2559173 pdxK 4188516 pdxK Escherichia coli 536 pyridoxal kinase YP_670332.1 2558322 R 362663 CDS YP_670333.1 110642603 4188517 2559372..2559647 1 NC_008253.1 hypothetical protein 2559647 4188517 ECP_2443 Escherichia coli 536 hypothetical protein YP_670333.1 2559372 D 362663 CDS YP_670334.1 110642604 4188518 complement(2559650..2560561) 1 NC_008253.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2560561 cysM 4188518 cysM Escherichia coli 536 cysteine synthase B YP_670334.1 2559650 R 362663 CDS YP_670335.1 110642605 4188519 complement(2560696..2561793) 1 NC_008253.1 sulfate/thiosulfate transporter subunit 2561793 4188519 ECP_2445 Escherichia coli 536 sulfate/thiosulfate transporter subunit YP_670335.1 2560696 R 362663 CDS YP_670336.1 110642606 4188520 complement(2561783..2562658) 1 NC_008253.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2562658 cysW 4188520 cysW Escherichia coli 536 sulfate/thiosulfate transporter permease subunit YP_670336.1 2561783 R 362663 CDS YP_670337.1 110642607 4188521 complement(2562658..2563491) 1 NC_008253.1 sulfate/thiosulfate transporter subunit 2563491 4188521 ECP_2447 Escherichia coli 536 sulfate/thiosulfate transporter subunit YP_670337.1 2562658 R 362663 CDS YP_670338.1 110642608 4188522 complement(2563491..2564507) 1 NC_008253.1 thiosulfate transporter subunit 2564507 4188522 ECP_2448 Escherichia coli 536 thiosulfate transporter subunit YP_670338.1 2563491 R 362663 CDS YP_670339.1 110642609 4188523 complement(2564665..2565456) 1 NC_008253.1 short chain dehydrogenase 2565456 4188523 ECP_2449 Escherichia coli 536 short chain dehydrogenase YP_670339.1 2564665 R 362663 CDS YP_670340.1 110642610 4188524 2565736..2566632 1 NC_008253.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2566632 murQ 4188524 murQ Escherichia coli 536 N-acetylmuramic acid 6-phosphate etherase YP_670340.1 2565736 D 362663 CDS YP_670341.1 110642611 4188525 2566636..2568060 1 NC_008253.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; N-acetylmuramic acid phosphotransfer permease 2568060 murP 4188525 murP Escherichia coli 536 N-acetylmuramic acid phosphotransfer permease YP_670341.1 2566636 D 362663 CDS YP_670342.1 110642612 4188526 complement(2568238..2569137) 1 NC_008253.1 iron-dependent peroxidase 2569137 4188526 ECP_2452 Escherichia coli 536 iron-dependent peroxidase YP_670342.1 2568238 R 362663 CDS YP_670343.1 110642613 4188527 complement(2569233..2569808) 1 NC_008253.1 hypothetical protein 2569808 4188527 ECP_2453 Escherichia coli 536 hypothetical protein YP_670343.1 2569233 R 362663 CDS YP_670344.1 110642614 4188528 complement(2569869..2570318) 1 NC_008253.1 hypothetical protein 2570318 4188528 ECP_2454 Escherichia coli 536 hypothetical protein YP_670344.1 2569869 R 362663 CDS YP_670345.1 110642615 4188529 complement(2570305..2570730) 1 NC_008253.1 acetyltransferase 2570730 4188529 ECP_2455 Escherichia coli 536 acetyltransferase YP_670345.1 2570305 R 362663 CDS YP_670346.1 110642616 4188530 2570944..2571813 1 NC_008253.1 N-acetylmuramoyl-L-alanine amidase 2571813 4188530 ECP_2456 Escherichia coli 536 N-acetylmuramoyl-L-alanine amidase YP_670346.1 2570944 D 362663 CDS YP_670347.1 110642617 4191706 2571817..2572716 1 NC_008253.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2572716 4191706 ECP_2457 Escherichia coli 536 coproporphyrinogen III oxidase YP_670347.1 2571817 D 362663 CDS YP_670348.1 110642618 4191707 complement(2572722..2573774) 1 NC_008253.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2573774 4191707 ECP_2458 Escherichia coli 536 transcriptional regulator EutR YP_670348.1 2572722 R 362663 CDS YP_670349.1 110642619 4191708 complement(2573820..2574320) 1 NC_008253.1 ethanolamine utilization protein EutK 2574320 4191708 ECP_2459 Escherichia coli 536 ethanolamine utilization protein EutK YP_670349.1 2573820 R 362663 CDS YP_670350.1 110642620 4191709 complement(2574333..2574992) 1 NC_008253.1 ethanolamine utilization protein EutL 2574992 4191709 ECP_2460 Escherichia coli 536 ethanolamine utilization protein EutL YP_670350.1 2574333 R 362663 CDS YP_670351.1 110642621 4191710 complement(2575002..2575889) 1 NC_008253.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2575889 4191710 ECP_2461 Escherichia coli 536 ethanolamine ammonia-lyase small subunit YP_670351.1 2575002 R 362663 CDS YP_670352.1 110642622 4191711 complement(2575910..2577271) 1 NC_008253.1 ethanolamine ammonia-lyase heavy chain 2577271 4191711 ECP_2462 Escherichia coli 536 ethanolamine ammonia-lyase heavy chain YP_670352.1 2575910 R 362663 CDS YP_670353.1 110642623 4191712 complement(2577283..2578686) 1 NC_008253.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2578686 eutA 4191712 eutA Escherichia coli 536 reactivating factor for ethanolamine ammonia lyase YP_670353.1 2577283 R 362663 CDS YP_670354.1 110642624 4191713 complement(2578683..2579909) 1 NC_008253.1 ethanolamine utilization protein EutH 2579909 4191713 ECP_2464 Escherichia coli 536 ethanolamine utilization protein EutH YP_670354.1 2578683 R 362663 CDS YP_670355.1 110642625 4191714 complement(2580226..2581413) 1 NC_008253.1 ethanolamine utilization protein EutG 2581413 4191714 ECP_2465 Escherichia coli 536 ethanolamine utilization protein EutG YP_670355.1 2580226 R 362663 CDS YP_670356.1 110642626 4191715 complement(2581403..2582239) 1 NC_008253.1 ethanolamine utilization protein EutJ 2582239 4191715 ECP_2466 Escherichia coli 536 ethanolamine utilization protein EutJ YP_670356.1 2581403 R 362663 CDS YP_670357.1 110642627 4191716 complement(2582250..2583653) 1 NC_008253.1 ethanolamine utilization protein EutE 2583653 4191716 ECP_2467 Escherichia coli 536 ethanolamine utilization protein EutE YP_670357.1 2582250 R 362663 CDS YP_670358.1 110642628 4191717 complement(2583665..2583952) 1 NC_008253.1 ethanolamine utilization protein EutN 2583952 4191717 ECP_2468 Escherichia coli 536 ethanolamine utilization protein EutN YP_670358.1 2583665 R 362663 CDS YP_670359.1 110642629 4191718 complement(2584059..2584352) 1 NC_008253.1 ethanolamine utilization protein EutM 2584352 4191718 ECP_2469 Escherichia coli 536 ethanolamine utilization protein EutM YP_670359.1 2584059 R 362663 CDS YP_670360.1 110642630 4191719 complement(2584391..2585407) 1 NC_008253.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2585407 eutD 4191719 eutD Escherichia coli 536 phosphotransacetylase YP_670360.1 2584391 R 362663 CDS YP_670361.1 110642631 4191720 complement(2585404..2586207) 1 NC_008253.1 ethanolamine utilization cobalamin adenosyltransferase 2586207 4191720 ECP_2471 Escherichia coli 536 ethanolamine utilization cobalamin adenosyltransferase YP_670361.1 2585404 R 362663 CDS YP_670362.1 110642632 4191721 complement(2586204..2586905) 1 NC_008253.1 ethanolamine utilization protein EutQ 2586905 4191721 ECP_2472 Escherichia coli 536 ethanolamine utilization protein EutQ YP_670362.1 2586204 R 362663 CDS YP_670363.1 110642633 4191722 complement(2586880..2587359) 1 NC_008253.1 ethanolamine utilization protein EutP 2587359 4191722 ECP_2473 Escherichia coli 536 ethanolamine utilization protein EutP YP_670363.1 2586880 R 362663 CDS YP_670364.1 110642634 4191723 complement(2587372..2587707) 1 NC_008253.1 ethanolamine utilization protein EutS 2587707 4191723 ECP_2474 Escherichia coli 536 ethanolamine utilization protein EutS YP_670364.1 2587372 R 362663 CDS YP_670365.1 110642635 4191724 complement(2588000..2590279) 1 NC_008253.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2590279 4191724 ECP_2475 Escherichia coli 536 malic enzyme YP_670365.1 2588000 R 362663 CDS YP_670366.1 110642636 4189371 2590568..2591518 1 NC_008253.1 transaldolase A 2591518 4189371 ECP_2476 Escherichia coli 536 transaldolase A YP_670366.1 2590568 D 362663 CDS YP_670367.1 110642637 4189372 2591538..2593541 1 NC_008253.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2593541 4189372 ECP_2477 Escherichia coli 536 transketolase YP_670367.1 2591538 D 362663 CDS YP_670368.1 110642638 4189373 complement(2593618..2594661) 1 NC_008253.1 hypothetical protein 2594661 4189373 ECP_2478 Escherichia coli 536 hypothetical protein YP_670368.1 2593618 R 362663 CDS YP_670369.1 110642639 4189374 complement(2594787..2595362) 1 NC_008253.1 hypothetical protein 2595362 4189374 ECP_2479 Escherichia coli 536 hypothetical protein YP_670369.1 2594787 R 362663 CDS YP_670370.1 110642640 4189375 complement(2595430..2597409) 1 NC_008253.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 2597409 4189375 ECP_2480 Escherichia coli 536 oxidoreductase Fe-S binding subunit YP_670370.1 2595430 R 362663 CDS YP_670371.1 110642641 4189376 2597615..2599315 1 NC_008253.1 nitrate/nitrite sensor protein NarQ 2599315 4189376 ECP_2481 Escherichia coli 536 nitrate/nitrite sensor protein NarQ YP_670371.1 2597615 D 362663 CDS YP_670372.1 110642642 4189377 2599479..2602592 1 NC_008253.1 aminoglycoside/multidrug efflux system 2602592 4189377 ECP_2482 Escherichia coli 536 aminoglycoside/multidrug efflux system YP_670372.1 2599479 D 362663 CDS YP_670373.1 110642643 4189378 2602665..2602892 1 NC_008253.1 hypothetical protein 2602892 4189378 ECP_2483 Escherichia coli 536 hypothetical protein YP_670373.1 2602665 D 362663 CDS YP_670374.1 110642644 4189379 2603131..2603487 1 NC_008253.1 hypothetical protein 2603487 4189379 ECP_2484 Escherichia coli 536 hypothetical protein YP_670374.1 2603131 D 362663 CDS YP_670375.1 110642645 4189380 2603491..2604618 1 NC_008253.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2604618 4189380 ECP_2485 Escherichia coli 536 succinyl-diaminopimelate desuccinylase YP_670375.1 2603491 D 362663 CDS YP_670376.1 110642646 4189381 2604646..2604846 1 NC_008253.1 hypothetical protein 2604846 4189381 ECP_2486 Escherichia coli 536 hypothetical protein YP_670376.1 2604646 D 362663 CDS YP_670377.1 110642647 4189382 complement(2604927..2605625) 1 NC_008253.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 2605625 4189382 ECP_2487 Escherichia coli 536 esterase YP_670377.1 2604927 R 362663 CDS YP_670378.1 110642648 4189383 complement(2605699..2607714) 1 NC_008253.1 hypothetical protein 2607714 4189383 ECP_2488 Escherichia coli 536 hypothetical protein YP_670378.1 2605699 R 362663 CDS YP_670379.1 110642649 4189384 complement(2607729..2608592) 1 NC_008253.1 hypothetical protein 2608592 4189384 ECP_2489 Escherichia coli 536 hypothetical protein YP_670379.1 2607729 R 362663 CDS YP_670380.1 110642650 4189385 complement(2608760..2609473) 1 NC_008253.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2609473 4189385 ECP_2490 Escherichia coli 536 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_670380.1 2608760 R 362663 CDS YP_670381.1 110642651 4189386 complement(2609686..2610720) 1 NC_008253.1 lipoprotein 2610720 4189386 ECP_2491 Escherichia coli 536 lipoprotein YP_670381.1 2609686 R 362663 CDS YP_670382.1 110642652 4189387 complement(2610737..2611615) 1 NC_008253.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2611615 4189387 ECP_2492 Escherichia coli 536 dihydrodipicolinate synthase YP_670382.1 2610737 R 362663 CDS YP_670383.1 110642653 4189388 2611761..2612333 1 NC_008253.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2612333 gcvR 4189388 gcvR Escherichia coli 536 glycine cleavage system transcriptional repressor YP_670383.1 2611761 D 362663 CDS YP_670384.1 110642654 4189389 2612333..2612803 1 NC_008253.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2612803 bcp 4189389 bcp Escherichia coli 536 thioredoxin-dependent thiol peroxidase YP_670384.1 2612333 D 362663 CDS YP_670385.1 110642655 4189390 complement(2612902..2613963) 1 NC_008253.1 permease PerM 2613963 4189390 ECP_2495 Escherichia coli 536 permease PerM YP_670385.1 2612902 R 362663 CDS YP_670386.1 110642656 4187681 2614176..2615639 1 NC_008253.1 hypothetical protein 2615639 4187681 ECP_2496 Escherichia coli 536 hypothetical protein YP_670386.1 2614176 D 362663 CDS YP_670387.1 110642657 4187682 2615660..2616019 1 NC_008253.1 arsenate reductase 2616019 4187682 ECP_2497 Escherichia coli 536 arsenate reductase YP_670387.1 2615660 D 362663 CDS YP_670388.1 110642658 4187683 complement(2616157..2616903) 1 NC_008253.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2616903 4187683 ECP_2498 Escherichia coli 536 DNA replication initiation factor YP_670388.1 2616157 R 362663 CDS YP_670389.1 110642659 4187684 complement(2616953..2618242) 1 NC_008253.1 uracil transporter 2618242 4187684 ECP_2499 Escherichia coli 536 uracil transporter YP_670389.1 2616953 R 362663 CDS YP_670390.1 110642660 4187685 complement(2618328..2618954) 1 NC_008253.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2618954 upp 4187685 upp Escherichia coli 536 uracil phosphoribosyltransferase YP_670390.1 2618328 R 362663 CDS YP_670391.1 110642661 4187686 2619279..2620316 1 NC_008253.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2620316 4187686 ECP_2501 Escherichia coli 536 phosphoribosylaminoimidazole synthetase YP_670391.1 2619279 D 362663 CDS YP_670392.1 110642662 4187687 2620316..2620954 1 NC_008253.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2620954 purN 4187687 purN Escherichia coli 536 phosphoribosylglycinamide formyltransferase YP_670392.1 2620316 D 362663 CDS YP_670393.1 110642663 4187688 2621126..2623192 1 NC_008253.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2623192 4187688 ECP_2503 Escherichia coli 536 polyphosphate kinase YP_670393.1 2621126 D 362663 CDS YP_670394.1 110642664 4187689 2623197..2624738 1 NC_008253.1 exopolyphosphatase 2624738 4187689 ECP_2504 Escherichia coli 536 exopolyphosphatase YP_670394.1 2623197 D 362663 CDS YP_670395.1 110642665 4187690 complement(2624777..2627020) 1 NC_008253.1 hypothetical protein 2627020 4187690 ECP_2505 Escherichia coli 536 hypothetical protein YP_670395.1 2624777 R 362663 CDS YP_670397.1 110642667 4187692 2627877..2628392 1 NC_008253.1 hypothetical protein 2628392 4187692 ECP_2507 Escherichia coli 536 hypothetical protein YP_670397.1 2627877 D 362663 CDS YP_670398.1 110642668 4187693 2628408..2628947 1 NC_008253.1 hypothetical protein 2628947 4187693 ECP_2508 Escherichia coli 536 hypothetical protein YP_670398.1 2628408 D 362663 CDS YP_670399.1 110642669 4187694 complement(2629041..2630618) 1 NC_008253.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2630618 guaA 4187694 guaA Escherichia coli 536 GMP synthase YP_670399.1 2629041 R 362663 CDS YP_670400.1 110642670 4187695 complement(2630687..2632222) 1 NC_008253.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2632222 4187695 ECP_2510 Escherichia coli 536 inosine 5'-monophosphate dehydrogenase YP_670400.1 2630687 R 362663 CDS YP_670401.1 110642671 4187696 2632315..2633691 1 NC_008253.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2633691 xseA 4187696 xseA Escherichia coli 536 exodeoxyribonuclease VII large subunit YP_670401.1 2632315 D 362663 CDS YP_670402.1 110642672 4187697 complement(2633760..2641811) 1 NC_008253.1 outer membrane protein 2641811 4187697 ECP_2512 Escherichia coli 536 outer membrane protein YP_670402.1 2633760 R 362663 CDS YP_670403.1 110642673 4187698 complement(2641932..2642909) 1 NC_008253.1 outer membrane protein 2642909 4187698 ECP_2513 Escherichia coli 536 outer membrane protein YP_670403.1 2641932 R 362663 CDS YP_670404.1 110642674 4187699 complement(2642964..2645141) 1 NC_008253.1 intimin/invasin 2645141 4187699 ECP_2514 Escherichia coli 536 intimin/invasin YP_670404.1 2642964 R 362663 CDS YP_670405.1 110642675 4190294 complement(2645350..2645565) 1 NC_008253.1 hypothetical protein 2645565 4190294 ECP_2515 Escherichia coli 536 hypothetical protein YP_670405.1 2645350 R 362663 CDS YP_670406.1 110642676 4190295 complement(2645628..2647100) 1 NC_008253.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2647100 engA 4190295 engA Escherichia coli 536 GTP-binding protein EngA YP_670406.1 2645628 R 362663 CDS YP_670407.1 110642677 4190296 complement(2647218..2648396) 1 NC_008253.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2648396 4190296 ECP_2517 Escherichia coli 536 outer membrane protein assembly complex subunit YfgL YP_670407.1 2647218 R 362663 CDS YP_670408.1 110642678 4190297 complement(2648407..2649027) 1 NC_008253.1 hypothetical protein 2649027 4190297 ECP_2518 Escherichia coli 536 hypothetical protein YP_670408.1 2648407 R 362663 CDS YP_670409.1 110642679 4190298 complement(2649045..2650319) 1 NC_008253.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2650319 hisS 4190298 hisS Escherichia coli 536 histidyl-tRNA synthetase YP_670409.1 2649045 R 362663 CDS YP_670410.1 110642680 4190299 complement(2650430..2651548) 1 NC_008253.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2651548 ispG 4190299 ispG Escherichia coli 536 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_670410.1 2650430 R 362663 CDS YP_670411.1 110642681 4190300 complement(2651575..2652582) 1 NC_008253.1 hypothetical protein 2652582 4190300 ECP_2521 Escherichia coli 536 hypothetical protein YP_670411.1 2651575 R 362663 CDS YP_670412.1 110642682 4190301 complement(2652867..2654021) 1 NC_008253.1 hypothetical protein 2654021 4190301 ECP_2522 Escherichia coli 536 hypothetical protein YP_670412.1 2652867 R 362663 CDS YP_670413.1 110642683 4190302 complement(2654171..2654602) 1 NC_008253.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2654602 ndk 4190302 ndk Escherichia coli 536 nucleoside diphosphate kinase YP_670413.1 2654171 R 362663 CDS YP_670414.1 110642684 4190303 complement(2654751..2657063) 1 NC_008253.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2657063 4190303 ECP_2524 Escherichia coli 536 penicillin-binding protein 1C YP_670414.1 2654751 R 362663 CDS YP_670415.1 110642685 4190304 complement(2657064..2662025) 1 NC_008253.1 lipoprotein YfhM 2662025 4190304 ECP_2525 Escherichia coli 536 lipoprotein YfhM YP_670415.1 2657064 R 362663 CDS YP_670416.1 110642686 4190305 2662232..2663077 1 NC_008253.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2663077 sseA 4190305 sseA Escherichia coli 536 3-mercaptopyruvate sulfurtransferase YP_670416.1 2662232 D 362663 CDS YP_670417.1 110642687 4190306 complement(2663570..2664355) 1 NC_008253.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2664355 4190306 ECP_2527 Escherichia coli 536 enhanced serine sensitivity protein SseB YP_670417.1 2663570 R 362663 CDS YP_670418.1 110642688 4190307 complement(2664489..2665772) 1 NC_008253.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 2665772 4190307 ECP_2528 Escherichia coli 536 aminopeptidase YP_670418.1 2664489 R 362663 CDS YP_670419.1 110642689 4190308 complement(2665831..2666031) 1 NC_008253.1 hypothetical protein 2666031 4190308 ECP_2529 Escherichia coli 536 hypothetical protein YP_670419.1 2665831 R 362663 CDS YP_670420.1 110642690 4190309 complement(2666043..2666378) 1 NC_008253.1 (2Fe-2S) ferredoxin 2666378 4190309 ECP_2530 Escherichia coli 536 (2Fe-2S) ferredoxin YP_670420.1 2666043 R 362663 CDS YP_670421.1 110642691 4190310 complement(2666380..2668230) 1 NC_008253.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2668230 hscA 4190310 hscA Escherichia coli 536 chaperone protein HscA YP_670421.1 2666380 R 362663 CDS YP_670422.1 110642692 4190311 complement(2668247..2668762) 1 NC_008253.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2668762 hscB 4190311 hscB Escherichia coli 536 co-chaperone HscB YP_670422.1 2668247 R 362663 CDS YP_670423.1 110642693 4190312 complement(2668858..2669181) 1 NC_008253.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2669181 iscA 4190312 iscA Escherichia coli 536 iron-sulfur cluster assembly protein YP_670423.1 2668858 R 362663 CDS YP_670424.1 110642694 4190313 complement(2669198..2669584) 1 NC_008253.1 scaffold protein 2669584 4190313 ECP_2534 Escherichia coli 536 scaffold protein YP_670424.1 2669198 R 362663 CDS YP_670425.1 110642695 4190741 complement(2669612..2670826) 1 NC_008253.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2670826 4190741 ECP_2535 Escherichia coli 536 cysteine desulfurase YP_670425.1 2669612 R 362663 CDS YP_670426.1 110642696 4190742 complement(2670938..2671426) 1 NC_008253.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2671426 4190742 ECP_2536 Escherichia coli 536 DNA-binding transcriptional regulator IscR YP_670426.1 2670938 R 362663 CDS YP_670427.1 110642697 4190743 complement(2671696..2672436) 1 NC_008253.1 tRNA/rRNA methyltransferase YfhQ 2672436 4190743 ECP_2537 Escherichia coli 536 tRNA/rRNA methyltransferase YfhQ YP_670427.1 2671696 R 362663 CDS YP_670428.1 110642698 4190744 2672555..2673358 1 NC_008253.1 inositol monophosphatase 2673358 4190744 ECP_2538 Escherichia coli 536 inositol monophosphatase YP_670428.1 2672555 D 362663 CDS YP_670429.1 110642699 4190745 2673503..2674357 1 NC_008253.1 hypothetical protein 2674357 4190745 ECP_2539 Escherichia coli 536 hypothetical protein YP_670429.1 2673503 D 362663 CDS YP_670430.1 110642700 4190746 2674548..2675828 1 NC_008253.1 stationary phase inducible protein CsiE 2675828 4190746 ECP_2540 Escherichia coli 536 stationary phase inducible protein CsiE YP_670430.1 2674548 D 362663 CDS YP_670431.1 110642701 4190747 complement(2675820..2676959) 1 NC_008253.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 2676959 4190747 ECP_2541 Escherichia coli 536 3-phenylpropionic acid transporter YP_670431.1 2675820 R 362663 CDS YP_670432.1 110642702 4190748 2677328..2677750 1 NC_008253.1 hypothetical protein 2677750 4190748 ECP_2542 Escherichia coli 536 hypothetical protein YP_670432.1 2677328 D 362663 CDS YP_670433.1 110642703 4190749 2677825..2678346 1 NC_008253.1 IS transposase 2678346 4190749 ECP_2543 Escherichia coli 536 IS transposase YP_670433.1 2677825 D 362663 CDS YP_670434.1 110642704 4190750 2678571..2679173 1 NC_008253.1 IS transposase 2679173 4190750 ECP_2544 Escherichia coli 536 IS transposase YP_670434.1 2678571 D 362663 CDS YP_670435.1 110642705 4190751 complement(2679346..2680218) 1 NC_008253.1 hypothetical protein 2680218 4190751 ECP_2545 Escherichia coli 536 hypothetical protein YP_670435.1 2679346 R 362663 CDS YP_670436.1 110642706 4190752 complement(2680230..2681324) 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YphC 2681324 4190752 ECP_2546 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YphC YP_670436.1 2680230 R 362663 CDS YP_670437.1 110642707 4190753 complement(2681357..2682355) 1 NC_008253.1 ABC transporter permease 2682355 4190753 ECP_2547 Escherichia coli 536 ABC transporter permease YP_670437.1 2681357 R 362663 CDS YP_670438.1 110642708 4190754 complement(2682380..2683891) 1 NC_008253.1 ABC transporter ATP-binding protein 2683891 4190754 ECP_2548 Escherichia coli 536 ABC transporter ATP-binding protein YP_670438.1 2682380 R 362663 CDS YP_670439.1 110642709 4190755 complement(2683914..2684897) 1 NC_008253.1 ABC transporter substrate-binding protein YphF 2684897 4190755 ECP_2549 Escherichia coli 536 ABC transporter substrate-binding protein YphF YP_670439.1 2683914 R 362663 CDS YP_670440.1 110642710 4190756 complement(2684994..2688275) 1 NC_008253.1 hypothetical protein 2688275 4190756 ECP_2550 Escherichia coli 536 hypothetical protein YP_670440.1 2684994 R 362663 CDS YP_670441.1 110642711 4190757 2688393..2689586 1 NC_008253.1 hypothetical protein 2689586 4190757 ECP_2551 Escherichia coli 536 hypothetical protein YP_670441.1 2688393 D 362663 CDS YP_670442.1 110642712 4190758 complement(2689650..2690903) 1 NC_008253.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2690903 glyA 4190758 glyA Escherichia coli 536 serine hydroxymethyltransferase YP_670442.1 2689650 R 362663 CDS YP_670443.1 110642713 4190759 2691007..2691183 1 NC_008253.1 hypothetical protein 2691183 4190759 ECP_2553 Escherichia coli 536 hypothetical protein YP_670443.1 2691007 D 362663 CDS YP_670444.1 110642714 4190760 2691232..2692422 1 NC_008253.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2692422 4190760 ECP_2554 Escherichia coli 536 nitric oxide dioxygenase YP_670444.1 2691232 D 362663 CDS YP_670445.1 110642715 4190761 complement(2692467..2692805) 1 NC_008253.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2692805 4190761 ECP_2555 Escherichia coli 536 nitrogen regulatory protein P-II 1 YP_670445.1 2692467 R 362663 CDS YP_670446.1 110642716 4190762 complement(2692866..2694200) 1 NC_008253.1 hypothetical protein 2694200 4190762 ECP_2556 Escherichia coli 536 hypothetical protein YP_670446.1 2692866 R 362663 CDS YP_670447.1 110642717 4190763 complement(2694190..2694903) 1 NC_008253.1 hypothetical protein 2694903 4190763 ECP_2557 Escherichia coli 536 hypothetical protein YP_670447.1 2694190 R 362663 CDS YP_670448.1 110642718 4190764 complement(2695068..2696558) 1 NC_008253.1 sensor-like histidine kinase YfhK 2696558 4190764 ECP_2558 Escherichia coli 536 sensor-like histidine kinase YfhK YP_670448.1 2695068 R 362663 CDS YP_670449.1 110642719 4190765 complement(2697071..2700958) 1 NC_008253.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2700958 4190765 ECP_2559 Escherichia coli 536 phosphoribosylformylglycinamidine synthase YP_670449.1 2697071 R 362663 CDS YP_670450.1 110642720 4190766 2701216..2702772 1 NC_008253.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2702772 4190766 ECP_2560 Escherichia coli 536 transglycosylase YP_670450.1 2701216 D 362663 CDS YP_670451.1 110642721 4190767 complement(2702769..2703305) 1 NC_008253.1 tRNA-specific adenosine deaminase 2703305 4190767 ECP_2561 Escherichia coli 536 tRNA-specific adenosine deaminase YP_670451.1 2702769 R 362663 CDS YP_670452.1 110642722 4190768 complement(2703330..2703965) 1 NC_008253.1 hypothetical protein 2703965 4190768 ECP_2562 Escherichia coli 536 hypothetical protein YP_670452.1 2703330 R 362663 CDS YP_670453.1 110642723 4190769 2704174..2705022 1 NC_008253.1 DNA-binding transcriptional regulator 2705022 4190769 ECP_2563 Escherichia coli 536 DNA-binding transcriptional regulator YP_670453.1 2704174 D 362663 CDS YP_670454.1 110642724 4190770 2705078..2705338 1 NC_008253.1 ferredoxin-like protein YfhL 2705338 4190770 ECP_2564 Escherichia coli 536 ferredoxin-like protein YfhL YP_670454.1 2705078 D 362663 CDS YP_670455.1 110642725 4190771 complement(2706033..2706413) 1 NC_008253.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2706413 acpS 4190771 acpS Escherichia coli 536 4'-phosphopantetheinyl transferase YP_670455.1 2706033 R 362663 CDS YP_670456.1 110642726 4190772 complement(2706413..2707144) 1 NC_008253.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2707144 4190772 ECP_2566 Escherichia coli 536 pyridoxine 5'-phosphate synthase YP_670456.1 2706413 R 362663 CDS YP_670457.1 110642727 4190773 complement(2707156..2707884) 1 NC_008253.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2707884 recO 4190773 recO Escherichia coli 536 DNA repair protein RecO YP_670457.1 2707156 R 362663 CDS YP_670458.1 110642728 4190774 complement(2707896..2708801) 1 NC_008253.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2708801 era 4190774 era Escherichia coli 536 GTP-binding protein Era YP_670458.1 2707896 R 362663 CDS YP_670459.1 110642729 4190775 complement(2708798..2709478) 1 NC_008253.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2709478 rnc 4190775 rnc Escherichia coli 536 ribonuclease III YP_670459.1 2708798 R 362663 CDS YP_670460.1 110642730 4190776 complement(2709745..2710719) 1 NC_008253.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2710719 4190776 ECP_2570 Escherichia coli 536 signal peptidase I YP_670460.1 2709745 R 362663 CDS YP_670461.1 110642731 4190777 complement(2710735..2712534) 1 NC_008253.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2712534 4190777 ECP_2571 Escherichia coli 536 GTP-binding protein LepA YP_670461.1 2710735 R 362663 CDS YP_670462.1 110642732 4190778 complement(2712732..2713211) 1 NC_008253.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2713211 4190778 ECP_2572 Escherichia coli 536 SoxR reducing system protein RseC YP_670462.1 2712732 R 362663 CDS YP_670463.1 110642733 4190779 complement(2713208..2714164) 1 NC_008253.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2714164 rseB 4190779 rseB Escherichia coli 536 periplasmic negative regulator of sigmaE YP_670463.1 2713208 R 362663 CDS YP_670464.1 110642734 4189219 complement(2714164..2714814) 1 NC_008253.1 anti-RNA polymerase sigma factor SigE 2714814 4189219 ECP_2574 Escherichia coli 536 anti-RNA polymerase sigma factor SigE YP_670464.1 2714164 R 362663 CDS YP_670465.1 110642735 4189220 complement(2714847..2715422) 1 NC_008253.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2715422 4189220 ECP_2575 Escherichia coli 536 RNA polymerase sigma factor RpoE YP_670465.1 2714847 R 362663 CDS YP_670466.1 110642736 4189221 2715830..2717452 1 NC_008253.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2717452 4189221 ECP_2576 Escherichia coli 536 L-aspartate oxidase YP_670466.1 2715830 D 362663 CDS YP_670467.1 110642737 4189222 complement(2717437..2718174) 1 NC_008253.1 hypothetical protein 2718174 4189222 ECP_2577 Escherichia coli 536 hypothetical protein YP_670467.1 2717437 R 362663 CDS YP_670468.1 110642738 4189223 2718306..2719640 1 NC_008253.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2719640 4189223 ECP_2578 Escherichia coli 536 ATP-dependent RNA helicase SrmB YP_670468.1 2718306 D 362663 CDS YP_670469.1 110642739 4189224 complement(2719673..2720554) 1 NC_008253.1 transcriptional regulator YfiE 2720554 4189224 ECP_2579 Escherichia coli 536 transcriptional regulator YfiE YP_670469.1 2719673 R 362663 CDS YP_670470.1 110642740 4189225 2720657..2721244 1 NC_008253.1 neutral amino-acid efflux protein 2721244 4189225 ECP_2580 Escherichia coli 536 neutral amino-acid efflux protein YP_670470.1 2720657 D 362663 CDS YP_670471.1 110642741 4189226 complement(2721300..2721683) 1 NC_008253.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2721683 4189226 ECP_2581 Escherichia coli 536 autonomous glycyl radical cofactor GrcA YP_670471.1 2721300 R 362663 CDS YP_670472.1 110642742 4189227 2721988..2722677 1 NC_008253.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2722677 4189227 ECP_2582 Escherichia coli 536 uracil-DNA glycosylase YP_670472.1 2721988 D 362663 CDS YP_670473.1 110642743 4189228 complement(2722725..2723762) 1 NC_008253.1 methyltransferase 2723762 4189228 ECP_2583 Escherichia coli 536 methyltransferase YP_670473.1 2722725 R 362663 CDS YP_670474.1 110642744 4189229 2723969..2724388 1 NC_008253.1 thioredoxin 2 2724388 4189229 ECP_2584 Escherichia coli 536 thioredoxin 2 YP_670474.1 2723969 D 362663 CDS YP_670475.1 110642745 4189230 2724433..2725155 1 NC_008253.1 hypothetical protein 2725155 4189230 ECP_2585 Escherichia coli 536 hypothetical protein YP_670475.1 2724433 D 362663 CDS YP_670476.1 110642746 4189231 2725187..2727847 1 NC_008253.1 hypothetical protein 2727847 4189231 ECP_2586 Escherichia coli 536 hypothetical protein YP_670476.1 2725187 D 362663 CDS YP_670477.1 110642747 4189232 2727961..2729316 1 NC_008253.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2729316 pssA 4189232 pssA Escherichia coli 536 phosphatidylserine synthase YP_670477.1 2727961 D 362663 CDS YP_670478.1 110642748 4189233 2729362..2729685 1 NC_008253.1 hypothetical protein 2729685 4189233 ECP_2588 Escherichia coli 536 hypothetical protein YP_670478.1 2729362 D 362663 CDS YP_670479.1 110642749 4189234 complement(2729682..2731073) 1 NC_008253.1 alpha-ketoglutarate transporter 2731073 4189234 ECP_2589 Escherichia coli 536 alpha-ketoglutarate transporter YP_670479.1 2729682 R 362663 CDS YP_670480.1 110642750 4189235 complement(2731323..2731541) 1 NC_008253.1 transposase 2731541 4189235 ECP_2590 Escherichia coli 536 transposase YP_670480.1 2731323 R 362663 CDS YP_670481.1 110642751 4189236 complement(2731637..2731969) 1 NC_008253.1 transposase 2731969 4189236 ECP_2591 Escherichia coli 536 transposase YP_670481.1 2731637 R 362663 CDS YP_670482.1 110642752 4189237 complement(2731885..2732289) 1 NC_008253.1 transposase 2732289 4189237 ECP_2592 Escherichia coli 536 transposase YP_670482.1 2731885 R 362663 CDS YP_670483.1 110642753 4189449 complement(2732533..2733135) 1 NC_008253.1 IS transposase 2733135 4189449 ECP_2593 Escherichia coli 536 IS transposase YP_670483.1 2732533 R 362663 CDS YP_670484.1 110642754 4189450 complement(2733360..2733881) 1 NC_008253.1 IS transposase 2733881 4189450 ECP_2594 Escherichia coli 536 IS transposase YP_670484.1 2733360 R 362663 CDS YP_670485.1 110642755 4189451 complement(2739465..2742038) 1 NC_008253.1 protein disaggregation chaperone 2742038 4189451 ECP_2595 Escherichia coli 536 protein disaggregation chaperone YP_670485.1 2739465 R 362663 CDS YP_670486.1 110642756 4189452 complement(2742168..2742899) 1 NC_008253.1 hypothetical protein 2742899 4189452 ECP_2596 Escherichia coli 536 hypothetical protein YP_670486.1 2742168 R 362663 CDS YP_670487.1 110642757 4189453 complement(2742896..2743876) 1 NC_008253.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2743876 rluD 4189453 rluD Escherichia coli 536 23S rRNA pseudouridine synthase D YP_670487.1 2742896 R 362663 CDS YP_670488.1 110642758 4189454 2744011..2744748 1 NC_008253.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2744748 4189454 ECP_2598 Escherichia coli 536 outer membrane protein assembly complex subunit YfiO YP_670488.1 2744011 D 362663 CDS YP_670489.1 110642759 4189455 2745018..2745359 1 NC_008253.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2745359 4189455 ECP_2599 Escherichia coli 536 translation inhibitor protein RaiA YP_670489.1 2745018 D 362663 CDS YP_670490.1 110642760 4189456 2745609..2746769 1 NC_008253.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2746769 pheA 4189456 pheA Escherichia coli 536 bifunctional chorismate mutase/prephenate dehydratase YP_670490.1 2745609 D 362663 CDS YP_670491.1 110642761 4189457 complement(2746812..2747933) 1 NC_008253.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 2747933 tyrA 4189457 tyrA Escherichia coli 536 bifunctional chorismate mutase/prephenate dehydrogenase YP_670491.1 2746812 R 362663 CDS YP_670492.1 110642762 4189458 complement(2747944..2749014) 1 NC_008253.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2749014 4189458 ECP_2602 Escherichia coli 536 phospho-2-dehydro-3-deoxyheptonate aldolase YP_670492.1 2747944 R 362663 CDS YP_670493.1 110642763 4189459 2749224..2749589 1 NC_008253.1 hypothetical protein 2749589 4189459 ECP_2603 Escherichia coli 536 hypothetical protein YP_670493.1 2749224 D 362663 CDS YP_670494.1 110642764 4189460 2749738..2750256 1 NC_008253.1 hypothetical protein 2750256 4189460 ECP_2604 Escherichia coli 536 hypothetical protein YP_670494.1 2749738 D 362663 CDS YP_670495.1 110642765 4189461 2750246..2751472 1 NC_008253.1 hypothetical protein 2751472 4189461 ECP_2605 Escherichia coli 536 hypothetical protein YP_670495.1 2750246 D 362663 CDS YP_670496.1 110642766 4189462 2751488..2751970 1 NC_008253.1 outer membrane lipoprotein 2751970 4189462 ECP_2606 Escherichia coli 536 outer membrane lipoprotein YP_670496.1 2751488 D 362663 CDS YP_670497.1 110642767 4189463 complement(2752047..2752394) 1 NC_008253.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 2752394 rplS 4189463 rplS Escherichia coli 536 50S ribosomal protein L19 YP_670497.1 2752047 R 362663 CDS YP_670498.1 110642768 4189464 complement(2752436..2753203) 1 NC_008253.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 2753203 trmD 4189464 trmD Escherichia coli 536 tRNA (guanine-N(1)-)-methyltransferase YP_670498.1 2752436 R 362663 CDS YP_670499.1 110642769 4189465 complement(2753234..2753782) 1 NC_008253.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 2753782 rimM 4189465 rimM Escherichia coli 536 16S rRNA-processing protein RimM YP_670499.1 2753234 R 362663 CDS YP_670500.1 110642770 4189466 complement(2753801..2754049) 1 NC_008253.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 2754049 rpsP 4189466 rpsP Escherichia coli 536 30S ribosomal protein S16 YP_670500.1 2753801 R 362663 CDS YP_670501.1 110642771 4189467 complement(2754186..2755547) 1 NC_008253.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 2755547 4189467 ECP_2611 Escherichia coli 536 signal recognition particle protein YP_670501.1 2754186 R 362663 CDS YP_670502.1 110642772 4189468 2755639..2756505 1 NC_008253.1 cytochrome C-type biogenesis protein 2756505 4189468 ECP_2612 Escherichia coli 536 cytochrome C-type biogenesis protein YP_670502.1 2755639 D 362663 CDS YP_670503.1 110642773 4187622 2756550..2757812 1 NC_008253.1 hypothetical protein 2757812 4187622 ECP_2613 Escherichia coli 536 hypothetical protein YP_670503.1 2756550 D 362663 CDS YP_670504.1 110642774 4187623 complement(2757867..2758460) 1 NC_008253.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2758460 4187623 ECP_2614 Escherichia coli 536 heat shock protein GrpE YP_670504.1 2757867 R 362663 CDS YP_670505.1 110642775 4187624 2758583..2759461 1 NC_008253.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2759461 ppnK 4187624 ppnK Escherichia coli 536 inorganic polyphosphate/ATP-NAD kinase YP_670505.1 2758583 D 362663 CDS YP_670506.1 110642776 4187625 2759547..2761208 1 NC_008253.1 recombination and repair protein 2761208 4187625 ECP_2616 Escherichia coli 536 recombination and repair protein YP_670506.1 2759547 D 362663 CDS YP_670507.1 110642777 4187626 2761357..2761698 1 NC_008253.1 hypothetical protein 2761698 4187626 ECP_2617 Escherichia coli 536 hypothetical protein YP_670507.1 2761357 D 362663 CDS YP_670508.1 110642778 4187627 complement(2761761..2762051) 1 NC_008253.1 hypothetical protein 2762051 4187627 ECP_2618 Escherichia coli 536 hypothetical protein YP_670508.1 2761761 R 362663 CDS YP_670509.1 110642779 4187628 complement(2762041..2762517) 1 NC_008253.1 hypothetical protein 2762517 4187628 ECP_2619 Escherichia coli 536 hypothetical protein YP_670509.1 2762041 R 362663 CDS YP_670510.1 110642780 4187629 2762649..2763131 1 NC_008253.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2763131 smpB 4187629 smpB Escherichia coli 536 SsrA-binding protein YP_670510.1 2762649 D 362663 CDS YP_670511.1 110642781 4187630 complement(2763710..2763892) 1 NC_008253.1 hypothetical protein 2763892 4187630 ECP_2621 Escherichia coli 536 hypothetical protein YP_670511.1 2763710 R 362663 CDS YP_670512.1 110642782 4187631 2764391..2765368 1 NC_008253.1 Gab-like protein; in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2765368 4187631 ECP_2622 Escherichia coli 536 hypothetical protein YP_670512.1 2764391 D 362663 CDS YP_670513.1 110642783 4187632 2765388..2766656 1 NC_008253.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2766656 4187632 ECP_2623 Escherichia coli 536 hydroxyglutarate oxidase YP_670513.1 2765388 D 362663 CDS YP_670514.1 110642784 4187633 2766679..2768127 1 NC_008253.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2768127 gabD 4187633 gabD Escherichia coli 536 succinate-semialdehyde dehydrogenase I YP_670514.1 2766679 D 362663 CDS YP_670515.1 110642785 4187634 2768141..2769421 1 NC_008253.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2769421 4187634 ECP_2625 Escherichia coli 536 4-aminobutyrate aminotransferase YP_670515.1 2768141 D 362663 CDS YP_670516.1 110642786 4187635 2769659..2771059 1 NC_008253.1 gamma-aminobutyrate transporter 2771059 4187635 ECP_2626 Escherichia coli 536 gamma-aminobutyrate transporter YP_670516.1 2769659 D 362663 CDS YP_670517.1 110642787 4187636 2771080..2771742 1 NC_008253.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2771742 4187636 ECP_2627 Escherichia coli 536 DNA-binding transcriptional regulator CsiR YP_670517.1 2771080 D 362663 CDS YP_670518.1 110642788 4187637 complement(2771743..2772192) 1 NC_008253.1 LysM domain/BON superfamily protein 2772192 4187637 ECP_2628 Escherichia coli 536 LysM domain/BON superfamily protein YP_670518.1 2771743 R 362663 CDS YP_670519.1 110642789 4187638 complement(2772276..2772434) 1 NC_008253.1 hypothetical protein 2772434 4187638 ECP_2629 Escherichia coli 536 hypothetical protein YP_670519.1 2772276 R 362663 CDS YP_670520.1 110642790 4187639 2772617..2772916 1 NC_008253.1 transcriptional regulator YgaV 2772916 4187639 ECP_2630 Escherichia coli 536 transcriptional regulator YgaV YP_670520.1 2772617 D 362663 CDS YP_670521.1 110642791 4187640 2772926..2773450 1 NC_008253.1 hypothetical protein 2773450 4187640 ECP_2631 Escherichia coli 536 hypothetical protein YP_670521.1 2772926 D 362663 CDS YP_670522.1 110642792 4190800 complement(2773497..2773901) 1 NC_008253.1 DNA binding protein 2773901 4190800 ECP_2632 Escherichia coli 536 DNA binding protein YP_670522.1 2773497 R 362663 CDS YP_670523.1 110642793 4190801 2774568..2775017 1 NC_008253.1 hypothetical protein 2775017 4190801 ECP_2633 Escherichia coli 536 hypothetical protein YP_670523.1 2774568 D 362663 CDS YP_670524.1 110642794 4190802 complement(2775054..2775398) 1 NC_008253.1 hypothetical protein 2775398 4190802 ECP_2634 Escherichia coli 536 hypothetical protein YP_670524.1 2775054 R 362663 CDS YP_670525.1 110642795 4190803 2775550..2775879 1 NC_008253.1 hypothetical protein 2775879 4190803 ECP_2635 Escherichia coli 536 hypothetical protein YP_670525.1 2775550 D 362663 CDS YP_670526.1 110642796 4190804 complement(2775936..2777270) 1 NC_008253.1 GntR family transcriptional regulator 2777270 4190804 ECP_2636 Escherichia coli 536 GntR family transcriptional regulator YP_670526.1 2775936 R 362663 CDS YP_670527.1 110642797 4190805 2777358..2777789 1 NC_008253.1 hypothetical protein 2777789 4190805 ECP_2637 Escherichia coli 536 hypothetical protein YP_670527.1 2777358 D 362663 CDS YP_670528.1 110642798 4190806 2777998..2778243 1 NC_008253.1 glutaredoxin-like protein 2778243 4190806 ECP_2638 Escherichia coli 536 glutaredoxin-like protein YP_670528.1 2777998 D 362663 CDS YP_670529.1 110642799 4190807 2778240..2778650 1 NC_008253.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2778650 nrdI 4190807 nrdI Escherichia coli 536 ribonucleotide reductase stimulatory protein YP_670529.1 2778240 D 362663 CDS YP_670530.1 110642800 4190808 2778662..2780767 1 NC_008253.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2780767 4190808 ECP_2640 Escherichia coli 536 ribonucleotide-diphosphate reductase subunit alpha YP_670530.1 2778662 D 362663 CDS YP_670531.1 110642801 4190809 2780777..2781736 1 NC_008253.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2781736 nrdF 4190809 nrdF Escherichia coli 536 ribonucleotide-diphosphate reductase subunit beta YP_670531.1 2780777 D 362663 CDS YP_670532.1 110642802 4190810 2781881..2782102 1 NC_008253.1 hypothetical protein 2782102 4190810 ECP_2642 Escherichia coli 536 hypothetical protein YP_670532.1 2781881 D 362663 CDS YP_670533.1 110642803 4190811 2782092..2783294 1 NC_008253.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2783294 4190811 ECP_2643 Escherichia coli 536 glycine betaine transporter ATP-binding subunit YP_670533.1 2782092 D 362663 CDS YP_670534.1 110642804 4190812 2783287..2784351 1 NC_008253.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2784351 4190812 ECP_2644 Escherichia coli 536 glycine betaine transporter membrane protein YP_670534.1 2783287 D 362663 CDS YP_670535.1 110642805 4190813 2784409..2785401 1 NC_008253.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2785401 proX 4190813 proX Escherichia coli 536 glycine betaine transporter periplasmic subunit YP_670535.1 2784409 D 362663 CDS YP_670536.1 110642806 4190814 2785593..2786777 1 NC_008253.1 transmembrane transport protein 2786777 4190814 ECP_2646 Escherichia coli 536 transmembrane transport protein YP_670536.1 2785593 D 362663 CDS YP_670537.1 110642807 4190815 2786901..2787638 1 NC_008253.1 hypothetical protein 2787638 4190815 ECP_2647 Escherichia coli 536 hypothetical protein YP_670537.1 2786901 D 362663 CDS YP_670538.1 110642808 4190816 2787628..2787963 1 NC_008253.1 hypothetical protein 2787963 4190816 ECP_2648 Escherichia coli 536 hypothetical protein YP_670538.1 2787628 D 362663 CDS YP_670539.1 110642809 4190817 2788054..2788584 1 NC_008253.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2788584 4190817 ECP_2649 Escherichia coli 536 transcriptional repressor MprA YP_670539.1 2788054 D 362663 CDS YP_670540.1 110642810 4190818 2788711..2789883 1 NC_008253.1 multidrug resistance protein A 2789883 4190818 ECP_2650 Escherichia coli 536 multidrug resistance protein A YP_670540.1 2788711 D 362663 CDS YP_670541.1 110642811 4190819 2789900..2791438 1 NC_008253.1 multidrug resistance protein B 2791438 4190819 ECP_2651 Escherichia coli 536 multidrug resistance protein B YP_670541.1 2789900 D 362663 CDS YP_670542.1 110642812 4190722 complement(2791502..2792017) 1 NC_008253.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2792017 4190722 ECP_2652 Escherichia coli 536 S-ribosylhomocysteinase YP_670542.1 2791502 R 362663 CDS YP_670543.1 110642813 4190723 complement(2792167..2793723) 1 NC_008253.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 2793723 4190723 ECP_2653 Escherichia coli 536 glutamate--cysteine ligase YP_670543.1 2792167 R 362663 CDS YP_670544.1 110642814 4190724 complement(2793796..2794224) 1 NC_008253.1 hypothetical protein 2794224 4190724 ECP_2654 Escherichia coli 536 hypothetical protein YP_670544.1 2793796 R 362663 CDS YP_670545.1 110642815 4190725 complement(2794221..2794787) 1 NC_008253.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 2794787 4190725 ECP_2655 Escherichia coli 536 fructose-1-phosphatase YP_670545.1 2794221 R 362663 CDS YP_670546.1 110642816 4190726 complement(2795842..2796027) 1 NC_008253.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 2796027 4190726 ECP_2656 Escherichia coli 536 carbon storage regulator YP_670546.1 2795842 R 362663 CDS YP_670547.1 110642817 4190727 complement(2796262..2798892) 1 NC_008253.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 2798892 alaS 4190727 alaS Escherichia coli 536 alanyl-tRNA synthetase YP_670547.1 2796262 R 362663 CDS YP_670548.1 110642818 4190728 complement(2799021..2799521) 1 NC_008253.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 2799521 recX 4190728 recX Escherichia coli 536 recombination regulator RecX YP_670548.1 2799021 R 362663 CDS YP_670549.1 110642819 4190729 complement(2799590..2800651) 1 NC_008253.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 2800651 recA 4190729 recA Escherichia coli 536 recombinase A YP_670549.1 2799590 R 362663 CDS YP_670550.1 110642820 4190730 complement(2800731..2801228) 1 NC_008253.1 competence damage-inducible protein A 2801228 4190730 ECP_2660 Escherichia coli 536 competence damage-inducible protein A YP_670550.1 2800731 R 362663 CDS YP_670551.1 110642821 4190731 complement(2801373..2802506) 1 NC_008253.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 2802506 4190731 ECP_2661 Escherichia coli 536 murein hydrolase B YP_670551.1 2801373 R 362663 CDS YP_670552.1 110642822 4190732 2802715..2803278 1 NC_008253.1 PTS family, glucitol/sorbitol-specific enzyme IIC component,one of two IIC components 2803278 4190732 ECP_2662 Escherichia coli 536 PTS family, glucitol/sorbitol-specific enzyme IIC component,one of two IIC components YP_670552.1 2802715 D 362663 CDS YP_670553.1 110642823 4190733 2803275..2804234 1 NC_008253.1 PTS system, glucitol/sorbitol-specific IIBC component 2804234 4190733 ECP_2663 Escherichia coli 536 PTS system, glucitol/sorbitol-specific IIBC component YP_670553.1 2803275 D 362663 CDS YP_670554.1 110642824 4190734 2804245..2804616 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; glucitol/sorbitol-specific PTS system component IIA 2804616 4190734 ECP_2664 Escherichia coli 536 glucitol/sorbitol-specific PTS system component IIA YP_670554.1 2804245 D 362663 CDS YP_670555.1 110642825 4190735 2804620..2805399 1 NC_008253.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2805399 4190735 ECP_2665 Escherichia coli 536 sorbitol-6-phosphate dehydrogenase YP_670555.1 2804620 D 362663 CDS YP_670556.1 110642826 4190736 2805505..2805864 1 NC_008253.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2805864 4190736 ECP_2666 Escherichia coli 536 DNA-binding transcriptional activator GutM YP_670556.1 2805505 D 362663 CDS YP_670557.1 110642827 4190737 2805931..2806704 1 NC_008253.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2806704 srlR 4190737 srlR Escherichia coli 536 DNA-binding transcriptional repressor SrlR YP_670557.1 2805931 D 362663 CDS YP_670558.1 110642828 4190738 2806697..2807662 1 NC_008253.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2807662 gutQ 4190738 gutQ Escherichia coli 536 D-arabinose 5-phosphate isomerase YP_670558.1 2806697 D 362663 CDS YP_670559.1 110642829 4190739 complement(2807659..2809173) 1 NC_008253.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 2809173 4190739 ECP_2669 Escherichia coli 536 anaerobic nitric oxide reductase transcriptional regulator YP_670559.1 2807659 R 362663 CDS YP_670560.1 110642830 4190740 2809360..2810799 1 NC_008253.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2810799 4190740 ECP_2670 Escherichia coli 536 anaerobic nitric oxide reductase flavorubredoxin YP_670560.1 2809360 D 362663 CDS YP_670561.1 110642831 4189565 2810796..2811929 1 NC_008253.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2811929 4189565 ECP_2671 Escherichia coli 536 nitric oxide reductase YP_670561.1 2810796 D 362663 CDS YP_670562.1 110642832 4189566 complement(2812151..2814403) 1 NC_008253.1 hydrogenase maturation protein HypF 2814403 4189566 ECP_2672 Escherichia coli 536 hydrogenase maturation protein HypF YP_670562.1 2812151 R 362663 CDS YP_670563.1 110642833 4189567 complement(2814556..2815083) 1 NC_008253.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 2815083 4189567 ECP_2673 Escherichia coli 536 electron transport protein HydN YP_670563.1 2814556 R 362663 CDS YP_670564.1 110642834 4189568 complement(2815061..2815228) 1 NC_008253.1 hypothetical protein 2815228 4189568 ECP_2674 Escherichia coli 536 hypothetical protein YP_670564.1 2815061 R 362663 CDS YP_670565.1 110642835 4189569 complement(2815232..2816245) 1 NC_008253.1 cryptic asc operon repressor 2816245 4189569 ECP_2675 Escherichia coli 536 cryptic asc operon repressor YP_670565.1 2815232 R 362663 CDS YP_670566.1 110642836 4189570 2816502..2817959 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; cellobiose/arbutin/salicin-specific PTS system components IIBC 2817959 4189570 ECP_2676 Escherichia coli 536 cellobiose/arbutin/salicin-specific PTS system components IIBC YP_670566.1 2816502 D 362663 CDS YP_670567.1 110642837 4189571 2817968..2819392 1 NC_008253.1 cryptic 6-phospho-beta-glucosidase 2819392 4189571 ECP_2677 Escherichia coli 536 cryptic 6-phospho-beta-glucosidase YP_670567.1 2817968 D 362663 CDS YP_670568.1 110642838 4189572 complement(2819490..2819909) 1 NC_008253.1 HTH-type transcriptional regulator YgjM 2819909 4189572 ECP_2678 Escherichia coli 536 HTH-type transcriptional regulator YgjM YP_670568.1 2819490 R 362663 CDS YP_670569.1 110642839 4189573 complement(2819935..2820102) 1 NC_008253.1 hypothetical protein 2820102 4189573 ECP_2679 Escherichia coli 536 hypothetical protein YP_670569.1 2819935 R 362663 CDS YP_670570.1 110642840 4189574 complement(2820145..2820615) 1 NC_008253.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 2820615 hycI 4189574 hycI Escherichia coli 536 hydrogenase 3 maturation protease YP_670570.1 2820145 R 362663 CDS YP_670571.1 110642841 4189575 complement(2820608..2821018) 1 NC_008253.1 formate hydrogenlyase maturation protein HYch 2821018 4189575 ECP_2681 Escherichia coli 536 formate hydrogenlyase maturation protein HYch YP_670571.1 2820608 R 362663 CDS YP_670572.1 110642842 4189576 complement(2821015..2821782) 1 NC_008253.1 formate hydrogenlyase-3 component G 2821782 4189576 ECP_2682 Escherichia coli 536 formate hydrogenlyase-3 component G YP_670572.1 2821015 R 362663 CDS YP_670573.1 110642843 4189577 complement(2821782..2822324) 1 NC_008253.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 2822324 4189577 ECP_2683 Escherichia coli 536 formate hydrogenlyase complex iron-sulfur subunit YP_670573.1 2821782 R 362663 CDS YP_670574.1 110642844 4189578 complement(2822334..2824043) 1 NC_008253.1 formate hydrogenase-3 component E 2824043 4189578 ECP_2684 Escherichia coli 536 formate hydrogenase-3 component E YP_670574.1 2822334 R 362663 CDS YP_670575.1 110642845 4189579 complement(2824061..2824984) 1 NC_008253.1 formate hydrogenlyase subunit 4 2824984 4189579 ECP_2685 Escherichia coli 536 formate hydrogenlyase subunit 4 YP_670575.1 2824061 R 362663 CDS YP_670576.1 110642846 4189580 complement(2824987..2826813) 1 NC_008253.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 2826813 4189580 ECP_2686 Escherichia coli 536 formate hydrogenlyase subunit 3 YP_670576.1 2824987 R 362663 CDS YP_670577.1 110642847 4189581 complement(2826810..2827421) 1 NC_008253.1 formate hydrogenase-3 component B 2827421 4189581 ECP_2687 Escherichia coli 536 formate hydrogenase-3 component B YP_670577.1 2826810 R 362663 CDS YP_670578.1 110642848 4189582 complement(2827546..2828007) 1 NC_008253.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 2828007 4189582 ECP_2688 Escherichia coli 536 formate hydrogenlyase regulatory protein HycA YP_670578.1 2827546 R 362663 CDS YP_670579.1 110642849 4189583 2828219..2828569 1 NC_008253.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2828569 hypA 4189583 hypA Escherichia coli 536 hydrogenase nickel incorporation protein YP_670579.1 2828219 D 362663 CDS YP_670580.1 110642850 4189584 2828573..2829445 1 NC_008253.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2829445 4189584 ECP_2690 Escherichia coli 536 hydrogenase nickel incorporation protein HypB YP_670580.1 2828573 D 362663 CDS YP_670581.1 110642851 4190424 2829436..2829708 1 NC_008253.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2829708 4190424 ECP_2691 Escherichia coli 536 hydrogenase assembly chaperone YP_670581.1 2829436 D 362663 CDS YP_670582.1 110642852 4190425 2829708..2830829 1 NC_008253.1 hydrogenase isoenzymes formation protein HYpd 2830829 4190425 ECP_2692 Escherichia coli 536 hydrogenase isoenzymes formation protein HYpd YP_670582.1 2829708 D 362663 CDS YP_670583.1 110642853 4190426 2830826..2831836 1 NC_008253.1 hydrogenase isoenzymes formation protein HypE 2831836 4190426 ECP_2693 Escherichia coli 536 hydrogenase isoenzymes formation protein HypE YP_670583.1 2830826 D 362663 CDS YP_670584.1 110642854 4190427 2831910..2833988 1 NC_008253.1 formate hydrogenlyase transcriptional activator 2833988 4190427 ECP_2694 Escherichia coli 536 formate hydrogenlyase transcriptional activator YP_670584.1 2831910 D 362663 CDS YP_670585.1 110642855 4190428 2834033..2834461 1 NC_008253.1 molybdenum-pterin-binding protein 2834461 4190428 ECP_2695 Escherichia coli 536 molybdenum-pterin-binding protein YP_670585.1 2834033 D 362663 CDS YP_670586.1 110642856 4190429 complement(2834500..2834844) 1 NC_008253.1 hypothetical protein 2834844 4190429 ECP_2696 Escherichia coli 536 hypothetical protein YP_670586.1 2834500 R 362663 CDS YP_670587.1 110642857 4190430 complement(2834899..2835054) 1 NC_008253.1 hypothetical protein 2835054 4190430 ECP_2697 Escherichia coli 536 hypothetical protein YP_670587.1 2834899 R 362663 CDS YP_670588.1 110642858 4190431 2835907..2836404 1 NC_008253.1 hypothetical protein 2836404 4190431 ECP_2698 Escherichia coli 536 hypothetical protein YP_670588.1 2835907 D 362663 CDS YP_670589.1 110642859 4190432 complement(2836428..2837312) 1 NC_008253.1 hypothetical protein 2837312 4190432 ECP_2699 Escherichia coli 536 hypothetical protein YP_670589.1 2836428 R 362663 CDS YP_670590.1 110642860 4190433 2837717..2837917 1 NC_008253.1 hypothetical protein 2837917 4190433 ECP_2700 Escherichia coli 536 hypothetical protein YP_670590.1 2837717 D 362663 CDS YP_670591.1 110642861 4190434 2838745..2839782 1 NC_008253.1 transposase 2839782 4190434 ECP_2701 Escherichia coli 536 transposase YP_670591.1 2838745 D 362663 CDS YP_670592.1 110642862 4190435 complement(2839884..2841254) 1 NC_008253.1 hypothetical protein 2841254 4190435 ECP_2702 Escherichia coli 536 hypothetical protein YP_670592.1 2839884 R 362663 CDS YP_670593.1 110642863 4190436 complement(2841293..2842072) 1 NC_008253.1 transposase/IS protein 2842072 4190436 ECP_2703 Escherichia coli 536 transposase/IS protein YP_670593.1 2841293 R 362663 CDS YP_670594.1 110642864 4190437 complement(2842072..2842428) 1 NC_008253.1 transposase 2842428 4190437 ECP_2704 Escherichia coli 536 transposase YP_670594.1 2842072 R 362663 CDS YP_670595.1 110642865 4190438 2842488..2842790 1 NC_008253.1 transposase 2842790 4190438 ECP_2705 Escherichia coli 536 transposase YP_670595.1 2842488 D 362663 CDS YP_670596.1 110642866 4190439 2842817..2843656 1 NC_008253.1 transposase 2843656 4190439 ECP_2706 Escherichia coli 536 transposase YP_670596.1 2842817 D 362663 CDS YP_670597.1 110642867 4190440 complement(2843660..2844346) 1 NC_008253.1 transposase 2844346 4190440 ECP_2707 Escherichia coli 536 transposase YP_670597.1 2843660 R 362663 CDS YP_670598.1 110642868 4190441 2844403..2844642 1 NC_008253.1 hypothetical protein 2844642 4190441 ECP_2708 Escherichia coli 536 hypothetical protein YP_670598.1 2844403 D 362663 CDS YP_670599.1 110642869 4190442 complement(2844856..2848707) 1 NC_008253.1 hypothetical protein 2848707 4190442 ECP_2709 Escherichia coli 536 hypothetical protein YP_670599.1 2844856 R 362663 CDS YP_670600.1 110642870 4189982 complement(2848976..2849725) 1 NC_008253.1 hypothetical protein 2849725 4189982 ECP_2710 Escherichia coli 536 hypothetical protein YP_670600.1 2848976 R 362663 CDS YP_670601.1 110642871 4189983 2849946..2852507 1 NC_008253.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2852507 4189983 ECP_2711 Escherichia coli 536 DNA mismatch repair protein MutS YP_670601.1 2849946 D 362663 CDS YP_670602.1 110642872 4189984 2852613..2853269 1 NC_008253.1 serine/threonine-specific protein phosphatase 2 2853269 4189984 ECP_2712 Escherichia coli 536 serine/threonine-specific protein phosphatase 2 YP_670602.1 2852613 D 362663 CDS YP_670603.1 110642873 4189985 complement(2853320..2854117) 1 NC_008253.1 DeoR family transcriptional regulator 2854117 4189985 ECP_2713 Escherichia coli 536 DeoR family transcriptional regulator YP_670603.1 2853320 R 362663 CDS YP_670604.1 110642874 4189986 2854283..2855191 1 NC_008253.1 oxidoreductase YgbJ 2855191 4189986 ECP_2714 Escherichia coli 536 oxidoreductase YgbJ YP_670604.1 2854283 D 362663 CDS YP_670605.1 110642875 4189987 2855188..2856450 1 NC_008253.1 hypothetical protein 2856450 4189987 ECP_2715 Escherichia coli 536 hypothetical protein YP_670605.1 2855188 D 362663 CDS YP_670606.1 110642876 4189988 2856447..2857085 1 NC_008253.1 aldolase 2857085 4189988 ECP_2716 Escherichia coli 536 aldolase YP_670606.1 2856447 D 362663 CDS YP_670607.1 110642877 4189989 2857090..2857866 1 NC_008253.1 endonuclease; hypothetical protein 2857866 4189989 ECP_2717 Escherichia coli 536 hypothetical protein YP_670607.1 2857090 D 362663 CDS YP_670608.1 110642878 4189990 2857955..2858560 1 NC_008253.1 hypothetical protein 2858560 4189990 ECP_2718 Escherichia coli 536 hypothetical protein YP_670608.1 2857955 D 362663 CDS YP_670609.1 110642879 4189991 2858574..2859320 1 NC_008253.1 hypothetical protein 2859320 4189991 ECP_2719 Escherichia coli 536 hypothetical protein YP_670609.1 2858574 D 362663 CDS YP_670610.1 110642880 4189992 complement(2859463..2860506) 1 NC_008253.1 beta-lactamase-like protein 2860506 4189992 ECP_2720 Escherichia coli 536 beta-lactamase-like protein YP_670610.1 2859463 R 362663 CDS YP_670611.1 110642881 4189993 2860731..2861282 1 NC_008253.1 hypothetical protein 2861282 4189993 ECP_2721 Escherichia coli 536 hypothetical protein YP_670611.1 2860731 D 362663 CDS YP_670612.1 110642882 4189994 complement(2861460..2862452) 1 NC_008253.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 2862452 4189994 ECP_2722 Escherichia coli 536 RNA polymerase sigma factor RpoS YP_670612.1 2861460 R 362663 CDS YP_670613.1 110642883 4189995 complement(2862515..2863654) 1 NC_008253.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 2863654 nlpD 4189995 nlpD Escherichia coli 536 lipoprotein NlpD YP_670613.1 2862515 R 362663 CDS YP_670614.1 110642884 4189996 complement(2863794..2863946) 1 NC_008253.1 protein-L-isoaspartate O-methyltransferase 2863946 4189996 ECP_2724 Escherichia coli 536 protein-L-isoaspartate O-methyltransferase YP_670614.1 2863794 R 362663 CDS YP_670615.1 110642885 4189997 complement(2864085..2864420) 1 NC_008253.1 protein-L-isoaspartate O-methyltransferase 2864420 4189997 ECP_2725 Escherichia coli 536 protein-L-isoaspartate O-methyltransferase YP_670615.1 2864085 R 362663 CDS YP_670616.1 110642886 4189998 complement(2864414..2865175) 1 NC_008253.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 2865175 surE 4189998 surE Escherichia coli 536 stationary phase survival protein SurE YP_670616.1 2864414 R 362663 CDS YP_670617.1 110642887 4189999 complement(2865156..2866205) 1 NC_008253.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 2866205 truD 4189999 truD Escherichia coli 536 tRNA pseudouridine synthase D YP_670617.1 2865156 R 362663 CDS YP_670618.1 110642888 4190000 complement(2866202..2866681) 1 NC_008253.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2866681 ispF 4190000 ispF Escherichia coli 536 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_670618.1 2866202 R 362663 CDS YP_670619.1 110642889 4190001 complement(2866681..2867391) 1 NC_008253.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2867391 ispD 4190001 ispD Escherichia coli 536 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_670619.1 2866681 R 362663 CDS YP_670620.1 110642890 4191555 complement(2867410..2867721) 1 NC_008253.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 2867721 ftsB 4191555 ftsB Escherichia coli 536 cell division protein FtsB YP_670620.1 2867410 R 362663 CDS YP_670621.1 110642891 4191556 complement(2867914..2868237) 1 NC_008253.1 hypothetical protein 2868237 4191556 ECP_2731 Escherichia coli 536 hypothetical protein YP_670621.1 2867914 R 362663 CDS YP_670622.1 110642892 4191557 complement(2868287..2868892) 1 NC_008253.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 2868892 4191557 ECP_2732 Escherichia coli 536 adenylylsulfate kinase YP_670622.1 2868287 R 362663 CDS YP_670623.1 110642893 4191558 complement(2868892..2870319) 1 NC_008253.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 2870319 cysN 4191558 cysN Escherichia coli 536 sulfate adenylyltransferase subunit 1 YP_670623.1 2868892 R 362663 CDS YP_670624.1 110642894 4191559 complement(2870321..2871229) 1 NC_008253.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 2871229 4191559 ECP_2734 Escherichia coli 536 sulfate adenylyltransferase subunit 2 YP_670624.1 2870321 R 362663 CDS YP_670625.1 110642895 4191560 2871481..2872518 1 NC_008253.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 2872518 4191560 ECP_2735 Escherichia coli 536 alkaline phosphatase YP_670625.1 2871481 D 362663 CDS YP_670626.1 110642896 4191561 complement(2873061..2873795) 1 NC_008253.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 2873795 4191561 ECP_2736 Escherichia coli 536 phosphoadenosine phosphosulfate reductase YP_670626.1 2873061 R 362663 CDS YP_670627.1 110642897 4191562 complement(2873869..2875581) 1 NC_008253.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 2875581 4191562 ECP_2737 Escherichia coli 536 sulfite reductase subunit beta YP_670627.1 2873869 R 362663 CDS YP_670628.1 110642898 4191563 complement(2875581..2877380) 1 NC_008253.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 2877380 cysJ 4191563 cysJ Escherichia coli 536 sulfite reductase subunit alpha YP_670628.1 2875581 R 362663 CDS YP_670629.1 110642899 4191564 2877696..2878061 1 NC_008253.1 6-pyruvoyl tetrahydrobiopterin synthase 2878061 4191564 ECP_2739 Escherichia coli 536 6-pyruvoyl tetrahydrobiopterin synthase YP_670629.1 2877696 D 362663 CDS YP_670630.1 110642900 4191565 2878139..2879410 1 NC_008253.1 electron transfer flavoprotein-quinone oxidoreductase YgcN 2879410 4191565 ECP_2740 Escherichia coli 536 electron transfer flavoprotein-quinone oxidoreductase YgcN YP_670630.1 2878139 D 362663 CDS YP_670631.1 110642901 4191566 2879401..2879661 1 NC_008253.1 ferredoxin-like protein YgcO 2879661 4191566 ECP_2741 Escherichia coli 536 ferredoxin-like protein YgcO YP_670631.1 2879401 D 362663 CDS YP_670632.1 110642902 4191567 2879678..2880253 1 NC_008253.1 anti-terminator regulatory protein YgcP 2880253 4191567 ECP_2742 Escherichia coli 536 anti-terminator regulatory protein YgcP YP_670632.1 2879678 D 362663 CDS YP_670633.1 110642903 4191568 complement(2880400..2881260) 1 NC_008253.1 electron transfer flavoprotein subunit YgcQ 2881260 4191568 ECP_2743 Escherichia coli 536 electron transfer flavoprotein subunit YgcQ YP_670633.1 2880400 R 362663 CDS YP_670634.1 110642904 4191569 complement(2881257..2882051) 1 NC_008253.1 electron transfer flavoprotein subunit YgcR 2882051 4191569 ECP_2744 Escherichia coli 536 electron transfer flavoprotein subunit YgcR YP_670634.1 2881257 R 362663 CDS YP_670635.1 110642905 4191570 complement(2882014..2883351) 1 NC_008253.1 metabolite transport protein YgcS 2883351 4191570 ECP_2745 Escherichia coli 536 metabolite transport protein YgcS YP_670635.1 2882014 R 362663 CDS YP_670636.1 110642906 4191571 complement(2883445..2884899) 1 NC_008253.1 flavoprotein YgcU 2884899 4191571 ECP_2746 Escherichia coli 536 flavoprotein YgcU YP_670636.1 2883445 R 362663 CDS YP_670637.1 110642907 4191572 complement(2884969..2885754) 1 NC_008253.1 oxidoreductase YgcW 2885754 4191572 ECP_2747 Escherichia coli 536 oxidoreductase YgcW YP_670637.1 2884969 R 362663 CDS YP_670638.1 110642908 4191573 2886072..2887349 1 NC_008253.1 hypothetical protein 2887349 4191573 ECP_2748 Escherichia coli 536 hypothetical protein YP_670638.1 2886072 D 362663 CDS YP_670639.1 110642909 4191648 2887376..2888854 1 NC_008253.1 sugar kinase 2888854 4191648 ECP_2749 Escherichia coli 536 sugar kinase YP_670639.1 2887376 D 362663 CDS YP_670640.1 110642910 4191649 2889019..2889939 1 NC_008253.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2889939 4191649 ECP_2750 Escherichia coli 536 aminoimidazole riboside kinase YP_670640.1 2889019 D 362663 CDS YP_670641.1 110642911 4191650 2890107..2891624 1 NC_008253.1 sucrose porin 2891624 4191650 ECP_2751 Escherichia coli 536 sucrose porin YP_670641.1 2890107 D 362663 CDS YP_670642.1 110642912 4191651 2891685..2893055 1 NC_008253.1 PTS system, sucrose-specific IIBC component 2893055 4191651 ECP_2752 Escherichia coli 536 PTS system, sucrose-specific IIBC component YP_670642.1 2891685 D 362663 CDS YP_670643.1 110642913 4191652 2893055..2894464 1 NC_008253.1 sucrose-6-phosphate hydrolase 2894464 4191652 ECP_2753 Escherichia coli 536 sucrose-6-phosphate hydrolase YP_670643.1 2893055 D 362663 CDS YP_670644.1 110642914 4191653 2894490..2895497 1 NC_008253.1 sucrose operon repressor 2895497 4191653 ECP_2754 Escherichia coli 536 sucrose operon repressor YP_670644.1 2894490 D 362663 CDS YP_670645.1 110642915 4191654 complement(2895582..2896253) 1 NC_008253.1 hypothetical protein 2896253 4191654 ECP_2755 Escherichia coli 536 hypothetical protein YP_670645.1 2895582 R 362663 CDS YP_670646.1 110642916 4191655 2896426..2897028 1 NC_008253.1 hypothetical protein 2897028 4191655 ECP_2756 Escherichia coli 536 hypothetical protein YP_670646.1 2896426 D 362663 CDS YP_670647.1 110642917 4191656 2897042..2897950 1 NC_008253.1 hypothetical protein 2897950 4191656 ECP_2757 Escherichia coli 536 hypothetical protein YP_670647.1 2897042 D 362663 CDS YP_670648.1 110642918 4191657 2897965..2899113 1 NC_008253.1 hypothetical protein 2899113 4191657 ECP_2758 Escherichia coli 536 hypothetical protein YP_670648.1 2897965 D 362663 CDS YP_670649.1 110642919 4191658 2899119..2899991 1 NC_008253.1 hypothetical protein 2899991 4191658 ECP_2759 Escherichia coli 536 hypothetical protein YP_670649.1 2899119 D 362663 CDS YP_670650.1 110642920 4191659 complement(2900051..2901349) 1 NC_008253.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 2901349 eno 4191659 eno Escherichia coli 536 phosphopyruvate hydratase YP_670650.1 2900051 R 362663 CDS YP_670651.1 110642921 4191660 complement(2901437..2903074) 1 NC_008253.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2903074 pyrG 4191660 pyrG Escherichia coli 536 CTP synthetase YP_670651.1 2901437 R 362663 CDS YP_670652.1 110642922 4191661 complement(2903302..2904093) 1 NC_008253.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 2904093 mazG 4191661 mazG Escherichia coli 536 nucleoside triphosphate pyrophosphohydrolase YP_670652.1 2903302 R 362663 CDS YP_670653.1 110642923 4191662 complement(2904165..2904500) 1 NC_008253.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 2904500 4191662 ECP_2763 Escherichia coli 536 toxin ChpA YP_670653.1 2904165 R 362663 CDS YP_670654.1 110642924 4191663 complement(2904500..2904748) 1 NC_008253.1 PemI-like protein 1; part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 2904748 4191663 ECP_2764 Escherichia coli 536 antitoxin MazE YP_670654.1 2904500 R 362663 CDS YP_670655.1 110642925 4191664 complement(2904826..2907060) 1 NC_008253.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 2907060 relA 4191664 relA Escherichia coli 536 GDP/GTP pyrophosphokinase YP_670655.1 2904826 R 362663 CDS YP_670656.1 110642926 4191665 complement(2907108..2908409) 1 NC_008253.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 2908409 rumA 4191665 rumA Escherichia coli 536 23S rRNA 5-methyluridine methyltransferase YP_670656.1 2907108 R 362663 CDS YP_670657.1 110642927 4191666 2908466..2911222 1 NC_008253.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2911222 4191666 ECP_2767 Escherichia coli 536 hybrid sensory histidine kinase BarA YP_670657.1 2908466 D 362663 CDS YP_670658.1 110642928 4191667 complement(2911453..2912793) 1 NC_008253.1 glucarate dehydratase 2912793 4191667 ECP_2768 Escherichia coli 536 glucarate dehydratase YP_670658.1 2911453 R 362663 CDS YP_670659.1 110642929 4189087 complement(2912814..2914154) 1 NC_008253.1 glucarate dehydratase 2914154 4189087 ECP_2769 Escherichia coli 536 glucarate dehydratase YP_670659.1 2912814 R 362663 CDS YP_670660.1 110642930 4189088 complement(2914156..2915508) 1 NC_008253.1 glucarate transporter 2915508 4189088 ECP_2770 Escherichia coli 536 glucarate transporter YP_670660.1 2914156 R 362663 CDS YP_670661.1 110642931 4189089 complement(2915942..2916391) 1 NC_008253.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 2916391 4189089 ECP_2771 Escherichia coli 536 flavodoxin YP_670661.1 2915942 R 362663 CDS YP_670662.1 110642932 4189090 complement(2916409..2917191) 1 NC_008253.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 2917191 4189090 ECP_2772 Escherichia coli 536 tRNA pseudouridine synthase C YP_670662.1 2916409 R 362663 CDS YP_670663.1 110642933 4189091 complement(2917191..2917520) 1 NC_008253.1 hypothetical protein 2917520 4189091 ECP_2773 Escherichia coli 536 hypothetical protein YP_670663.1 2917191 R 362663 CDS YP_670664.1 110642934 4189092 complement(2917767..2917907) 1 NC_008253.1 hypothetical protein 2917907 4189092 ECP_2774 Escherichia coli 536 hypothetical protein YP_670664.1 2917767 R 362663 CDS YP_670665.1 110642935 4189093 complement(2918142..2918687) 1 NC_008253.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 2918687 4189093 ECP_2775 Escherichia coli 536 SecY interacting protein Syd YP_670665.1 2918142 R 362663 CDS YP_670666.1 110642936 4189094 2918755..2919603 1 NC_008253.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 2919603 queF 4189094 queF Escherichia coli 536 7-cyano-7-deazaguanine reductase YP_670666.1 2918755 D 362663 CDS YP_670667.1 110642937 4189095 2919715..2921079 1 NC_008253.1 hypothetical protein 2921079 4189095 ECP_2777 Escherichia coli 536 hypothetical protein YP_670667.1 2919715 D 362663 CDS YP_670668.1 110642938 4189096 2921636..2922925 1 NC_008253.1 serine transporter 2922925 4189096 ECP_2778 Escherichia coli 536 serine transporter YP_670668.1 2921636 D 362663 CDS YP_670669.1 110642939 4189099 2924463..2925218 1 NC_008253.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 2925218 xni 4189099 xni Escherichia coli 536 exonuclease IX YP_670669.1 2924463 D 362663 CDS YP_670670.1 110642940 4189100 complement(2925323..2926474) 1 NC_008253.1 L-1,2-propanediol oxidoreductase 2926474 4189100 ECP_2782 Escherichia coli 536 L-1,2-propanediol oxidoreductase YP_670670.1 2925323 R 362663 CDS YP_670671.1 110642941 4189101 complement(2926499..2927146) 1 NC_008253.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 2927146 4189101 ECP_2783 Escherichia coli 536 L-fuculose phosphate aldolase YP_670671.1 2926499 R 362663 CDS YP_670672.1 110642942 4189102 2927693..2929009 1 NC_008253.1 L-fucose transporter 2929009 4189102 ECP_2784 Escherichia coli 536 L-fucose transporter YP_670672.1 2927693 D 362663 CDS YP_670673.1 110642943 4189103 2929042..2930817 1 NC_008253.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2930817 fucI 4189103 fucI Escherichia coli 536 L-fucose isomerase YP_670673.1 2929042 D 362663 CDS YP_670674.1 110642944 4187397 2930896..2932344 1 NC_008253.1 L-fuculokinase 2932344 4187397 ECP_2786 Escherichia coli 536 L-fuculokinase YP_670674.1 2930896 D 362663 CDS YP_670675.1 110642945 4187398 2932346..2932768 1 NC_008253.1 fucose operon FucU protein 2932768 4187398 ECP_2787 Escherichia coli 536 fucose operon FucU protein YP_670675.1 2932346 D 362663 CDS YP_670676.1 110642946 4187399 2932944..2933558 1 NC_008253.1 DNA-binding transcriptional activator 2933558 4187399 ECP_2788 Escherichia coli 536 DNA-binding transcriptional activator YP_670676.1 2932944 D 362663 CDS YP_670677.1 110642947 4187400 complement(2933602..2934702) 1 NC_008253.1 RNA 2'-O-ribose methyltransferase 2934702 4187400 ECP_2789 Escherichia coli 536 RNA 2'-O-ribose methyltransferase YP_670677.1 2933602 R 362663 CDS YP_670678.1 110642948 4187401 complement(2934695..2935090) 1 NC_008253.1 hypothetical protein 2935090 4187401 ECP_2790 Escherichia coli 536 hypothetical protein YP_670678.1 2934695 R 362663 CDS YP_670679.1 110642949 4187402 complement(2935109..2936026) 1 NC_008253.1 regulatory protein for glycine cleavage pathway; Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 2936026 4187402 ECP_2791 Escherichia coli 536 DNA-binding transcriptional activator GcvA YP_670679.1 2935109 R 362663 CDS YP_670680.1 110642950 4187403 complement(2936377..2936604) 1 NC_008253.1 lipoprotein 2936604 4187403 ECP_2792 Escherichia coli 536 lipoprotein YP_670680.1 2936377 R 362663 CDS YP_670681.1 110642951 4187404 2936796..2938001 1 NC_008253.1 cysteine sulfinate desulfinase 2938001 4187404 ECP_2793 Escherichia coli 536 cysteine sulfinate desulfinase YP_670681.1 2936796 D 362663 CDS YP_670682.1 110642952 4187405 2938001..2938444 1 NC_008253.1 hypothetical protein 2938444 4187405 ECP_2794 Escherichia coli 536 hypothetical protein YP_670682.1 2938001 D 362663 CDS YP_670683.1 110642953 4187406 complement(2938495..2939301) 1 NC_008253.1 hypothetical protein 2939301 4187406 ECP_2795 Escherichia coli 536 hypothetical protein YP_670683.1 2938495 R 362663 CDS YP_670684.2 162138277 4187407 complement(2939378..2940475) 1 NC_008253.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 2940475 mltA 4187407 mltA Escherichia coli 536 murein transglycosylase A YP_670684.2 2939378 R 362663 CDS YP_670685.1 110642955 4187411 2941612..2942112 1 NC_008253.1 hypothetical protein 2942112 4187411 ECP_2800 Escherichia coli 536 hypothetical protein YP_670685.1 2941612 D 362663 CDS YP_670686.1 110642956 4187412 2942171..2943709 1 NC_008253.1 hypothetical protein 2943709 4187412 ECP_2801 Escherichia coli 536 hypothetical protein YP_670686.1 2942171 D 362663 CDS YP_670687.1 110642957 4187413 2943727..2945064 1 NC_008253.1 hypothetical protein 2945064 4187413 ECP_2802 Escherichia coli 536 hypothetical protein YP_670687.1 2943727 D 362663 CDS YP_670688.1 110642958 4187414 2945061..2945726 1 NC_008253.1 hypothetical protein 2945726 4187414 ECP_2803 Escherichia coli 536 hypothetical protein YP_670688.1 2945061 D 362663 CDS YP_670689.1 110642959 4187415 2945739..2947391 1 NC_008253.1 OmpA family membrane protein 2947391 4187415 ECP_2804 Escherichia coli 536 OmpA family membrane protein YP_670689.1 2945739 D 362663 CDS YP_670690.1 110642960 4187416 2947449..2947940 1 NC_008253.1 hemolysin-coregulated protein Hcp 2947940 4187416 ECP_2805 Escherichia coli 536 hemolysin-coregulated protein Hcp YP_670690.1 2947449 D 362663 CDS YP_670691.1 110642961 4187417 2948132..2950768 1 NC_008253.1 CLPA/B-type chaperone protein 2950768 4187417 ECP_2806 Escherichia coli 536 CLPA/B-type chaperone protein YP_670691.1 2948132 D 362663 CDS YP_670692.1 110642962 4187418 2950780..2953269 1 NC_008253.1 VGR-related protein 2953269 4187418 ECP_2807 Escherichia coli 536 VGR-related protein YP_670692.1 2950780 D 362663 CDS YP_670693.1 110642963 4187419 2953335..2954153 1 NC_008253.1 transmembrane protein 2954153 4187419 ECP_2808 Escherichia coli 536 transmembrane protein YP_670693.1 2953335 D 362663 CDS YP_670694.1 110642964 4187420 2954167..2954760 1 NC_008253.1 hypothetical protein 2954760 4187420 ECP_2809 Escherichia coli 536 hypothetical protein YP_670694.1 2954167 D 362663 CDS YP_670695.1 110642965 4187421 2954805..2957324 1 NC_008253.1 VGR-related protein 2957324 4187421 ECP_2810 Escherichia coli 536 VGR-related protein YP_670695.1 2954805 D 362663 CDS YP_670696.1 110642966 4187422 2957317..2958105 1 NC_008253.1 hypothetical protein 2958105 4187422 ECP_2811 Escherichia coli 536 hypothetical protein YP_670696.1 2957317 D 362663 CDS YP_670697.1 110642967 4187423 2958190..2959110 1 NC_008253.1 hypothetical protein 2959110 4187423 ECP_2812 Escherichia coli 536 hypothetical protein YP_670697.1 2958190 D 362663 CDS YP_670698.1 110642968 4187424 2959367..2960581 1 NC_008253.1 hypothetical protein 2960581 4187424 ECP_2813 Escherichia coli 536 hypothetical protein YP_670698.1 2959367 D 362663 CDS YP_670699.1 110642969 4187425 2960533..2963964 1 NC_008253.1 hypothetical protein 2963964 4187425 ECP_2814 Escherichia coli 536 hypothetical protein YP_670699.1 2960533 D 362663 CDS YP_670700.1 110642970 4187426 2963930..2965567 1 NC_008253.1 hypothetical protein 2965567 4187426 ECP_2815 Escherichia coli 536 hypothetical protein YP_670700.1 2963930 D 362663 CDS YP_670701.1 110642971 4187427 2965573..2967003 1 NC_008253.1 hypothetical protein 2967003 4187427 ECP_2816 Escherichia coli 536 hypothetical protein YP_670701.1 2965573 D 362663 CDS YP_670702.1 110642972 4187428 2966996..2967400 1 NC_008253.1 hypothetical protein 2967400 4187428 ECP_2817 Escherichia coli 536 hypothetical protein YP_670702.1 2966996 D 362663 CDS YP_670703.1 110642973 4187429 2967475..2967792 1 NC_008253.1 hypothetical protein 2967792 4187429 ECP_2818 Escherichia coli 536 hypothetical protein YP_670703.1 2967475 D 362663 CDS YP_670704.1 110642974 4187430 2967749..2969236 1 NC_008253.1 hypothetical protein 2969236 4187430 ECP_2819 Escherichia coli 536 hypothetical protein YP_670704.1 2967749 D 362663 CDS YP_670705.1 110642975 4187431 2969200..2970279 1 NC_008253.1 hypothetical protein 2970279 4187431 ECP_2820 Escherichia coli 536 hypothetical protein YP_670705.1 2969200 D 362663 CDS YP_670706.1 110642976 4187432 2970260..2970796 1 NC_008253.1 hypothetical protein 2970796 4187432 ECP_2821 Escherichia coli 536 hypothetical protein YP_670706.1 2970260 D 362663 CDS YP_670707.1 110642977 4187584 2970800..2971228 1 NC_008253.1 hypothetical protein 2971228 4187584 ECP_2822 Escherichia coli 536 hypothetical protein YP_670707.1 2970800 D 362663 CDS YP_670708.1 110642978 4187585 2971228..2972604 1 NC_008253.1 hypothetical protein 2972604 4187585 ECP_2823 Escherichia coli 536 hypothetical protein YP_670708.1 2971228 D 362663 CDS YP_670709.1 110642979 4187586 complement(2972904..2973851) 1 NC_008253.1 2-hydroxyacid dehydrogenase 2973851 4187586 ECP_2824 Escherichia coli 536 2-hydroxyacid dehydrogenase YP_670709.1 2972904 R 362663 CDS YP_670710.1 110642980 4187587 complement(2973923..2974519) 1 NC_008253.1 posphosugar isomerase 2974519 4187587 ECP_2825 Escherichia coli 536 posphosugar isomerase YP_670710.1 2973923 R 362663 CDS YP_670711.1 110642981 4187588 complement(2974522..2975697) 1 NC_008253.1 aminotransferase 2975697 4187588 ECP_2826 Escherichia coli 536 aminotransferase YP_670711.1 2974522 R 362663 CDS YP_670712.1 110642982 4187589 complement(2975697..2977226) 1 NC_008253.1 PTS system, maltose and glucose-specific IIABC component 2977226 4187589 ECP_2827 Escherichia coli 536 PTS system, maltose and glucose-specific IIABC component YP_670712.1 2975697 R 362663 CDS YP_670713.1 110642983 4187590 complement(2977309..2978133) 1 NC_008253.1 transcriptional antiterminator protein 2978133 4187590 ECP_2828 Escherichia coli 536 transcriptional antiterminator protein YP_670713.1 2977309 R 362663 CDS YP_670714.1 110642984 4187591 complement(2978391..2979644) 1 NC_008253.1 amidase 2979644 4187591 ECP_2829 Escherichia coli 536 amidase YP_670714.1 2978391 R 362663 CDS YP_670715.1 110642985 4187592 2979876..2981207 1 NC_008253.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2981207 4187592 ECP_2830 Escherichia coli 536 N-acetylglutamate synthase YP_670715.1 2979876 D 362663 CDS YP_670716.1 110642986 4187593 complement(2981289..2983115) 1 NC_008253.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 2983115 recD 4187593 recD Escherichia coli 536 exonuclease V subunit alpha YP_670716.1 2981289 R 362663 CDS YP_670717.1 110642987 4187594 complement(2983115..2986657) 1 NC_008253.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 2986657 recB 4187594 recB Escherichia coli 536 exonuclease V subunit beta YP_670717.1 2983115 R 362663 CDS YP_670718.1 110642988 4187595 complement(2986650..2989538) 1 NC_008253.1 protease III 2989538 4187595 ECP_2833 Escherichia coli 536 protease III YP_670718.1 2986650 R 362663 CDS YP_670719.1 110642989 4187596 complement(2989714..2993082) 1 NC_008253.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 2993082 recC 4187596 recC Escherichia coli 536 exonuclease V subunit gamma YP_670719.1 2989714 R 362663 CDS YP_670720.1 110642990 4187597 complement(2993095..2993418) 1 NC_008253.1 hypothetical protein 2993418 4187597 ECP_2835 Escherichia coli 536 hypothetical protein YP_670720.1 2993095 R 362663 CDS YP_670721.1 110642991 4187598 complement(2993403..2993810) 1 NC_008253.1 hypothetical protein 2993810 4187598 ECP_2836 Escherichia coli 536 hypothetical protein YP_670721.1 2993403 R 362663 CDS YP_670722.1 110642992 4187599 complement(2993807..2994610) 1 NC_008253.1 hypothetical protein 2994610 4187599 ECP_2837 Escherichia coli 536 hypothetical protein YP_670722.1 2993807 R 362663 CDS YP_670723.1 110642993 4187600 complement(2994361..2994831) 1 NC_008253.1 hypothetical protein 2994831 4187600 ECP_2838 Escherichia coli 536 hypothetical protein YP_670723.1 2994361 R 362663 CDS YP_670725.1 110642995 4187602 complement(2995016..2995810) 1 NC_008253.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 2995810 thyA 4187602 thyA Escherichia coli 536 thymidylate synthase YP_670725.1 2995016 R 362663 CDS YP_670726.1 110642996 4188093 complement(2995817..2996692) 1 NC_008253.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2996692 4188093 ECP_2841 Escherichia coli 536 prolipoprotein diacylglyceryl transferase YP_670726.1 2995817 R 362663 CDS YP_670727.1 110642997 4188094 complement(2996843..2999089) 1 NC_008253.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 2999089 4188094 ECP_2842 Escherichia coli 536 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain YP_670727.1 2996843 R 362663 CDS YP_670728.1 110642998 4188095 complement(2999102..2999632) 1 NC_008253.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 2999632 4188095 ECP_2843 Escherichia coli 536 dinucleoside polyphosphate hydrolase YP_670728.1 2999102 R 362663 CDS YP_670729.1 110642999 4188096 3000317..3001006 1 NC_008253.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3001006 4188096 ECP_2844 Escherichia coli 536 DNA mismatch repair protein YP_670729.1 3000317 D 362663 CDS YP_670730.1 110643000 4188097 3001075..3001788 1 NC_008253.1 integral membrane transport protein 3001788 4188097 ECP_2845 Escherichia coli 536 integral membrane transport protein YP_670730.1 3001075 D 362663 CDS YP_670731.1 110643001 4188098 3001926..3002144 1 NC_008253.1 lipoprotein 3002144 4188098 ECP_2846 Escherichia coli 536 lipoprotein YP_670731.1 3001926 D 362663 CDS YP_670732.1 110643002 4188099 3002252..3003292 1 NC_008253.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3003292 tas 4188099 tas Escherichia coli 536 aldo-keto reductase YP_670732.1 3002252 D 362663 CDS YP_670733.1 110643003 4188100 complement(3003324..3004517) 1 NC_008253.1 lysophospholipid transporter LplT 3004517 4188100 ECP_2848 Escherichia coli 536 lysophospholipid transporter LplT YP_670733.1 3003324 R 362663 CDS YP_670734.1 110643004 4188101 complement(3004510..3006669) 1 NC_008253.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3006669 4188101 ECP_2849 Escherichia coli 536 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_670734.1 3004510 R 362663 CDS YP_670735.1 110643005 4188102 3007255..3008286 1 NC_008253.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3008286 4188102 ECP_2850 Escherichia coli 536 DNA-binding transcriptional regulator GalR YP_670735.1 3007255 D 362663 CDS YP_670736.1 110643006 4188103 complement(3008293..3009555) 1 NC_008253.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3009555 4188103 ECP_2851 Escherichia coli 536 diaminopimelate decarboxylase YP_670736.1 3008293 R 362663 CDS YP_670737.1 110643007 4188104 3009677..3010612 1 NC_008253.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3010612 4188104 ECP_2852 Escherichia coli 536 LysR family transcriptional regulator YP_670737.1 3009677 D 362663 CDS YP_670738.1 110643008 4188105 complement(3010599..3011291) 1 NC_008253.1 racemase 3011291 4188105 ECP_2853 Escherichia coli 536 racemase YP_670738.1 3010599 R 362663 CDS YP_670739.1 110643009 4188106 complement(3011420..3012838) 1 NC_008253.1 arabinose-proton symporter 3012838 4188106 ECP_2854 Escherichia coli 536 arabinose-proton symporter YP_670739.1 3011420 R 362663 CDS YP_670740.1 110643010 4188107 complement(3013153..3013914) 1 NC_008253.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3013914 4188107 ECP_2855 Escherichia coli 536 2-deoxy-D-gluconate 3-dehydrogenase YP_670740.1 3013153 R 362663 CDS YP_670741.1 110643011 4188108 complement(3013944..3014780) 1 NC_008253.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3014780 4188108 ECP_2856 Escherichia coli 536 5-keto-4-deoxyuronate isomerase YP_670741.1 3013944 R 362663 CDS YP_670742.1 110643012 4188109 complement(3015067..3016248) 1 NC_008253.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3016248 4188109 ECP_2857 Escherichia coli 536 acetyl-CoA acetyltransferase YP_670742.1 3015067 R 362663 CDS YP_670743.1 110643013 4188110 3016503..3017732 1 NC_008253.1 transporter 3017732 4188110 ECP_2858 Escherichia coli 536 transporter YP_670743.1 3016503 D 362663 CDS YP_670744.1 110643014 4188111 complement(3018200..3018955) 1 NC_008253.1 metalloendopeptidase 3018955 4188111 ECP_2859 Escherichia coli 536 metalloendopeptidase YP_670744.1 3018200 R 362663 CDS YP_670745.1 110643015 4188112 3019369..3021666 1 NC_008253.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3021666 4188112 ECP_2860 Escherichia coli 536 xanthine dehydrogenase subunit XdhA YP_670745.1 3019369 D 362663 CDS YP_670746.1 110643016 4189124 3021677..3022555 1 NC_008253.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3022555 4189124 ECP_2861 Escherichia coli 536 xanthine dehydrogenase subunit XdhB YP_670746.1 3021677 D 362663 CDS YP_670747.1 110643017 4189125 3022552..3023031 1 NC_008253.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3023031 4189125 ECP_2862 Escherichia coli 536 xanthine dehydrogenase subunit XdhC YP_670747.1 3022552 D 362663 CDS YP_670748.1 110643018 4189126 complement(3023071..3024849) 1 NC_008253.1 sigma-54-dependent transcriptional regulator YgeV 3024849 4189126 ECP_2863 Escherichia coli 536 sigma-54-dependent transcriptional regulator YgeV YP_670748.1 3023071 R 362663 CDS YP_670749.1 110643019 4189127 3025325..3026515 1 NC_008253.1 aspartate/ornithine carbamoyltransferase 3026515 4189127 ECP_2864 Escherichia coli 536 aspartate/ornithine carbamoyltransferase YP_670749.1 3025325 D 362663 CDS YP_670750.1 110643020 4189128 3026573..3027769 1 NC_008253.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3027769 4189128 ECP_2865 Escherichia coli 536 diaminopropionate ammonia-lyase YP_670750.1 3026573 D 362663 CDS YP_670751.1 110643021 4189129 3027827..3029038 1 NC_008253.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3029038 4189129 ECP_2866 Escherichia coli 536 peptidase YP_670751.1 3027827 D 362663 CDS YP_670752.1 110643022 4189130 3029091..3030476 1 NC_008253.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3030476 4189130 ECP_2867 Escherichia coli 536 phenylhydantoinase YP_670752.1 3029091 D 362663 CDS YP_670753.1 110643023 4189131 3030524..3031456 1 NC_008253.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3031456 4189131 ECP_2868 Escherichia coli 536 carbamate kinase YP_670753.1 3030524 D 362663 CDS YP_670754.1 110643024 4189132 complement(3031497..3033122) 1 NC_008253.1 hypothetical protein 3033122 4189132 ECP_2869 Escherichia coli 536 hypothetical protein YP_670754.1 3031497 R 362663 CDS YP_670755.1 110643025 4189133 complement(3033170..3033721) 1 NC_008253.1 hypothetical protein 3033721 4189133 ECP_2870 Escherichia coli 536 hypothetical protein YP_670755.1 3033170 R 362663 CDS YP_670756.1 110643026 4189134 3034092..3034622 1 NC_008253.1 hypothetical protein 3034622 4189134 ECP_2871 Escherichia coli 536 hypothetical protein YP_670756.1 3034092 D 362663 CDS YP_670757.1 110643027 4189135 3034944..3038042 1 NC_008253.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3038042 4189135 ECP_2872 Escherichia coli 536 selenate reductase subunit YgfK YP_670757.1 3034944 D 362663 CDS YP_670758.1 110643028 4189136 3038045..3039373 1 NC_008253.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3039373 4189136 ECP_2873 Escherichia coli 536 chlorohydrolase/aminohydrolase YP_670758.1 3038045 D 362663 CDS YP_670759.1 110643029 4189137 3039424..3040203 1 NC_008253.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3040203 4189137 ECP_2874 Escherichia coli 536 selenate reductase subunit YgfM YP_670759.1 3039424 D 362663 CDS YP_670760.1 110643030 4189138 3040200..3043070 1 NC_008253.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3043070 4189138 ECP_2875 Escherichia coli 536 selenate reductase subunit YgfN YP_670760.1 3040200 D 362663 CDS YP_670761.1 110643031 4189139 3043235..3044635 1 NC_008253.1 transmembrane transport protein 3044635 4189139 ECP_2876 Escherichia coli 536 transmembrane transport protein YP_670761.1 3043235 D 362663 CDS YP_670762.1 110643032 4189140 3044653..3045969 1 NC_008253.1 Catalyzes the deamination of guanine; guanine deaminase 3045969 4189140 ECP_2877 Escherichia coli 536 guanine deaminase YP_670762.1 3044653 D 362663 CDS YP_670763.1 110643033 4189141 3046005..3047372 1 NC_008253.1 hypothetical protein 3047372 4189141 ECP_2878 Escherichia coli 536 hypothetical protein YP_670763.1 3046005 D 362663 CDS YP_670764.1 110643034 4189142 complement(3047408..3047896) 1 NC_008253.1 electron transport protein YgfS 3047896 4189142 ECP_2879 Escherichia coli 536 electron transport protein YgfS YP_670764.1 3047408 R 362663 CDS YP_670765.1 110643035 4188863 complement(3047896..3049815) 1 NC_008253.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3049815 4188863 ECP_2880 Escherichia coli 536 oxidoreductase Fe-S binding subunit YP_670765.1 3047896 R 362663 CDS YP_670766.1 110643036 4188864 3050251..3051699 1 NC_008253.1 purine permease YgfU 3051699 4188864 ECP_2881 Escherichia coli 536 purine permease YgfU YP_670766.1 3050251 D 362663 CDS YP_670767.1 110643037 4188865 3051949..3052497 1 NC_008253.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3052497 4188865 ECP_2882 Escherichia coli 536 isopentenyl-diphosphate delta-isomerase YP_670767.1 3051949 D 362663 CDS YP_670768.1 110643038 4188866 complement(3052540..3054057) 1 NC_008253.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3054057 lysS 4188866 lysS Escherichia coli 536 lysyl-tRNA synthetase YP_670768.1 3052540 R 362663 CDS YP_670769.1 110643039 4188867 complement(3054067..3054948) 1 NC_008253.1 peptide chain release factor 2 3054948 4188867 ECP_2884 Escherichia coli 536 peptide chain release factor 2 YP_670769.1 3054067 R 362663 CDS YP_670770.1 110643040 4188868 complement(3055256..3056989) 1 NC_008253.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3056989 4188868 ECP_2885 Escherichia coli 536 ssDNA exonuclease RecJ YP_670770.1 3055256 R 362663 CDS YP_670771.1 110643041 4188869 complement(3056995..3057705) 1 NC_008253.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3057705 4188869 ECP_2886 Escherichia coli 536 thiol:disulfide interchange protein DsbC YP_670771.1 3056995 R 362663 CDS YP_670772.1 110643042 4188870 complement(3057730..3058626) 1 NC_008253.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3058626 xerD 4188870 xerD Escherichia coli 536 site-specific tyrosine recombinase XerD YP_670772.1 3057730 R 362663 CDS YP_670773.1 110643043 4188871 3058738..3059259 1 NC_008253.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3059259 4188871 ECP_2888 Escherichia coli 536 flavodoxin FldB YP_670773.1 3058738 D 362663 CDS YP_670774.1 110643044 4188872 complement(3059299..3059706) 1 NC_008253.1 hypothetical protein 3059706 4188872 ECP_2889 Escherichia coli 536 hypothetical protein YP_670774.1 3059299 R 362663 CDS YP_670775.1 110643045 4188873 complement(3059687..3059953) 1 NC_008253.1 hypothetical protein 3059953 4188873 ECP_2890 Escherichia coli 536 hypothetical protein YP_670775.1 3059687 R 362663 CDS YP_670776.1 110643046 4188874 3059937..3060119 1 NC_008253.1 hypothetical protein 3060119 4188874 ECP_2891 Escherichia coli 536 hypothetical protein YP_670776.1 3059937 D 362663 CDS YP_670777.1 110643047 4188875 3060196..3061176 1 NC_008253.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3061176 4188875 ECP_2892 Escherichia coli 536 global regulator YP_670777.1 3060196 D 362663 CDS YP_670778.1 110643048 4188876 complement(3061253..3061912) 1 NC_008253.1 hemolysin ( membrane protein) 3061912 4188876 ECP_2893 Escherichia coli 536 hemolysin ( membrane protein) YP_670778.1 3061253 R 362663 CDS YP_670779.1 110643049 4188877 complement(3062076..3062387) 1 NC_008253.1 hypothetical protein 3062387 4188877 ECP_2894 Escherichia coli 536 hypothetical protein YP_670779.1 3062076 R 362663 CDS YP_670780.1 110643050 4188878 3062432..3063865 1 NC_008253.1 6-phospho-beta-glucosidase 3063865 4188878 ECP_2895 Escherichia coli 536 6-phospho-beta-glucosidase YP_670780.1 3062432 D 362663 CDS YP_670781.1 110643051 4188879 complement(3064031..3066904) 1 NC_008253.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3066904 4188879 ECP_2896 Escherichia coli 536 glycine dehydrogenase YP_670781.1 3064031 R 362663 CDS YP_670782.1 110643052 4188880 complement(3067022..3067411) 1 NC_008253.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3067411 4188880 ECP_2897 Escherichia coli 536 glycine cleavage system protein H YP_670782.1 3067022 R 362663 CDS YP_670783.2 229560214 4188881 complement(3067435..3068529) 1 NC_008253.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3068529 gcvT 4188881 gcvT Escherichia coli 536 glycine cleavage system aminomethyltransferase T YP_670783.2 3067435 R 362663 CDS YP_670784.1 110643054 4188882 complement(3068977..3070179) 1 NC_008253.1 hypothetical protein 3070179 4188882 ECP_2899 Escherichia coli 536 hypothetical protein YP_670784.1 3068977 R 362663 CDS YP_670785.1 110643055 4190944 complement(3070202..3071380) 1 NC_008253.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3071380 4190944 ECP_2900 Escherichia coli 536 2-octaprenyl-6-methoxyphenyl hydroxylase YP_670785.1 3070202 R 362663 CDS YP_670786.1 110643056 4190945 complement(3071377..3072702) 1 NC_008253.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3072702 4190945 ECP_2901 Escherichia coli 536 proline aminopeptidase P II YP_670786.1 3071377 R 362663 CDS YP_670787.2 229560213 4190946 complement(3072728..3073306) 1 NC_008253.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3073306 4190946 ECP_2902 Escherichia coli 536 hypothetical protein YP_670787.2 3072728 R 362663 CDS YP_670788.1 110643058 4190947 3073474..3073803 1 NC_008253.1 Z-ring-associated protein 3073803 4190947 ECP_2903 Escherichia coli 536 Z-ring-associated protein YP_670788.1 3073474 D 362663 CDS YP_670789.2 229560212 4190948 3074103..3074651 1 NC_008253.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3074651 4190948 ECP_2904 Escherichia coli 536 ligase YP_670789.2 3074103 D 362663 CDS YP_670790.1 110643060 4190949 complement(3075041..3076273) 1 NC_008253.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3076273 4190949 ECP_2905 Escherichia coli 536 D-3-phosphoglycerate dehydrogenase YP_670790.1 3075041 R 362663 CDS YP_670791.1 110643061 4190950 complement(3076529..3077224) 1 NC_008253.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3077224 4190950 ECP_2906 Escherichia coli 536 ribose-5-phosphate isomerase A YP_670791.1 3076529 R 362663 CDS YP_670792.1 110643062 4190951 complement(3077244..3077522) 1 NC_008253.1 hypothetical protein 3077522 4190951 ECP_2907 Escherichia coli 536 hypothetical protein YP_670792.1 3077244 R 362663 CDS YP_670793.1 110643063 4190952 3077615..3078508 1 NC_008253.1 oriC replication inhibitor; specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3078508 4190952 ECP_2908 Escherichia coli 536 chromosome replication initiation inhibitor protein YP_670793.1 3077615 D 362663 CDS YP_670794.1 110643064 4190953 3078711..3079805 1 NC_008253.1 hypothetical protein 3079805 4190953 ECP_2909 Escherichia coli 536 hypothetical protein YP_670794.1 3078711 D 362663 CDS YP_670795.1 110643065 4190954 complement(3079802..3080698) 1 NC_008253.1 transcriptional regulator YgfI 3080698 4190954 ECP_2910 Escherichia coli 536 transcriptional regulator YgfI YP_670795.1 3079802 R 362663 CDS YP_670796.1 110643066 4190955 complement(3080856..3081548) 1 NC_008253.1 hypothetical protein 3081548 4190955 ECP_2911 Escherichia coli 536 hypothetical protein YP_670796.1 3080856 R 362663 CDS YP_670797.1 110643067 4190956 complement(3081689..3082324) 1 NC_008253.1 Involved in the export of arginine; arginine exporter protein 3082324 4190956 ECP_2912 Escherichia coli 536 arginine exporter protein YP_670797.1 3081689 R 362663 CDS YP_670798.1 110643068 4190957 complement(3082463..3083323) 1 NC_008253.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3083323 4190957 ECP_2913 Escherichia coli 536 mechanosensitive channel MscS YP_670798.1 3082463 R 362663 CDS YP_670799.1 110643069 4190958 complement(3083346..3084611) 1 NC_008253.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3084611 4190958 ECP_2914 Escherichia coli 536 fructose-bisphosphate aldolase YP_670799.1 3083346 R 362663 CDS YP_670800.1 110643070 4190959 complement(3084826..3085989) 1 NC_008253.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3085989 pgk 4190959 pgk Escherichia coli 536 phosphoglycerate kinase YP_670800.1 3084826 R 362663 CDS YP_670801.1 110643071 4190960 complement(3086039..3087058) 1 NC_008253.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3087058 4190960 ECP_2916 Escherichia coli 536 erythrose 4-phosphate dehydrogenase YP_670801.1 3086039 R 362663 CDS YP_670802.1 110643072 4190961 3087430..3087858 1 NC_008253.1 hypothetical protein 3087858 4190961 ECP_2917 Escherichia coli 536 hypothetical protein YP_670802.1 3087430 D 362663 CDS YP_670803.1 110643073 4190962 3087885..3088463 1 NC_008253.1 inner membrane protein 3088463 4190962 ECP_2918 Escherichia coli 536 inner membrane protein YP_670803.1 3087885 D 362663 CDS YP_670804.1 110643074 4188733 3088464..3089171 1 NC_008253.1 ABC transporter permease 3089171 4188733 ECP_2919 Escherichia coli 536 ABC transporter permease YP_670804.1 3088464 D 362663 CDS YP_670805.1 110643075 4188734 3089159..3089836 1 NC_008253.1 ABC transporter ATP-binding protein 3089836 4188734 ECP_2920 Escherichia coli 536 ABC transporter ATP-binding protein YP_670805.1 3089159 D 362663 CDS YP_670806.1 110643076 4188735 3089830..3090507 1 NC_008253.1 ABC transporter ATP-binding protein 3090507 4188735 ECP_2921 Escherichia coli 536 ABC transporter ATP-binding protein YP_670806.1 3089830 D 362663 CDS YP_670807.1 110643077 4188736 complement(3090479..3091192) 1 NC_008253.1 fructose transport system kinase 3091192 frcK 4188736 frcK Escherichia coli 536 fructose transport system kinase YP_670807.1 3090479 R 362663 CDS YP_670808.1 110643078 4188737 complement(3091189..3091698) 1 NC_008253.1 DNA-binding transcriptional regulator 3091698 4188737 ECP_2923 Escherichia coli 536 DNA-binding transcriptional regulator YP_670808.1 3091189 R 362663 CDS YP_670809.1 110643079 4188738 complement(3091847..3092035) 1 NC_008253.1 hypothetical protein 3092035 4188738 ECP_2924 Escherichia coli 536 hypothetical protein YP_670809.1 3091847 R 362663 CDS YP_670810.1 110643080 4188739 complement(3092032..3093309) 1 NC_008253.1 hypothetical protein 3093309 4188739 ECP_2925 Escherichia coli 536 hypothetical protein YP_670810.1 3092032 R 362663 CDS YP_670811.1 110643081 4188740 complement(3093324..3094712) 1 NC_008253.1 PTS system, mannitol (cryptic)-specific IIBC component 3094712 4188740 ECP_2926 Escherichia coli 536 PTS system, mannitol (cryptic)-specific IIBC component YP_670811.1 3093324 R 362663 CDS YP_670812.1 110643082 4188741 complement(3094740..3095183) 1 NC_008253.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3095183 cmtB 4188741 cmtB Escherichia coli 536 mannitol phosphotransferase subunit EIIA YP_670812.1 3094740 R 362663 CDS YP_670813.1 110643083 4188742 3095561..3096469 1 NC_008253.1 SPFH domain-containing protein 3096469 4188742 ECP_2928 Escherichia coli 536 SPFH domain-containing protein YP_670813.1 3095561 D 362663 CDS YP_670814.1 110643084 4188743 complement(3096689..3098680) 1 NC_008253.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3098680 4188743 ECP_2929 Escherichia coli 536 transketolase YP_670814.1 3096689 R 362663 CDS YP_670815.1 110643085 4188744 3098832..3099716 1 NC_008253.1 metalloprotease YggG 3099716 4188744 ECP_2930 Escherichia coli 536 metalloprotease YggG YP_670815.1 3098832 D 362663 CDS YP_670816.1 110643086 4188745 complement(3099807..3100727) 1 NC_008253.1 catalyzes the formation of putrescine from agmatine; agmatinase 3100727 4188745 ECP_2931 Escherichia coli 536 agmatinase YP_670816.1 3099807 R 362663 CDS YP_670817.1 110643087 4188746 complement(3100863..3101594) 1 NC_008253.1 hypothetical protein 3101594 4188746 ECP_2932 Escherichia coli 536 hypothetical protein YP_670817.1 3100863 R 362663 CDS YP_670818.1 110643088 4188747 complement(3101740..3103716) 1 NC_008253.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3103716 4188747 ECP_2933 Escherichia coli 536 arginine decarboxylase YP_670818.1 3101740 R 362663 CDS YP_670819.1 110643089 4188748 complement(3104204..3104455) 1 NC_008253.1 hypothetical protein 3104455 4188748 ECP_2934 Escherichia coli 536 hypothetical protein YP_670819.1 3104204 R 362663 CDS YP_670820.1 110643090 4188749 3104511..3105665 1 NC_008253.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3105665 4188749 ECP_2935 Escherichia coli 536 S-adenosylmethionine synthetase YP_670820.1 3104511 D 362663 CDS YP_670821.1 110643091 4188750 3105728..3105943 1 NC_008253.1 hypothetical protein 3105943 4188750 ECP_2936 Escherichia coli 536 hypothetical protein YP_670821.1 3105728 D 362663 CDS YP_670822.1 110643092 4188751 3106102..3107496 1 NC_008253.1 galactose-proton symporter 3107496 4188751 ECP_2937 Escherichia coli 536 galactose-proton symporter YP_670822.1 3106102 D 362663 CDS YP_670823.1 110643093 4188752 3107519..3108070 1 NC_008253.1 hypothetical protein 3108070 4188752 ECP_2938 Escherichia coli 536 hypothetical protein YP_670823.1 3107519 D 362663 CDS YP_670824.1 110643094 4188336 3108165..3108872 1 NC_008253.1 endonuclease I 3108872 4188336 ECP_2939 Escherichia coli 536 endonuclease I YP_670824.1 3108165 D 362663 CDS YP_670825.1 110643095 4188337 3108952..3109683 1 NC_008253.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3109683 4188337 ECP_2940 Escherichia coli 536 16S ribosomal RNA methyltransferase RsmE YP_670825.1 3108952 D 362663 CDS YP_670826.1 110643096 4188338 3109696..3110646 1 NC_008253.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3110646 4188338 ECP_2941 Escherichia coli 536 glutathione synthetase YP_670826.1 3109696 D 362663 CDS YP_670827.1 110643097 4188339 3110755..3111318 1 NC_008253.1 hypothetical protein 3111318 4188339 ECP_2942 Escherichia coli 536 hypothetical protein YP_670827.1 3110755 D 362663 CDS YP_670828.1 110643098 4188340 3111318..3111734 1 NC_008253.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3111734 4188340 ECP_2943 Escherichia coli 536 Holliday junction resolvase-like protein YP_670828.1 3111318 D 362663 CDS YP_670829.1 110643099 4188341 complement(3111908..3112888) 1 NC_008253.1 hypothetical protein 3112888 4188341 ECP_2944 Escherichia coli 536 hypothetical protein YP_670829.1 3111908 R 362663 CDS YP_670830.1 110643100 4188342 3112906..3113610 1 NC_008253.1 hypothetical protein 3113610 4188342 ECP_2945 Escherichia coli 536 hypothetical protein YP_670830.1 3112906 D 362663 CDS YP_670831.1 110643101 4188343 3113628..3114194 1 NC_008253.1 membrane protein YggT 3114194 4188343 ECP_2946 Escherichia coli 536 membrane protein YggT YP_670831.1 3113628 D 362663 CDS YP_670832.1 110643102 4188344 3114191..3114481 1 NC_008253.1 hypothetical protein 3114481 4188344 ECP_2947 Escherichia coli 536 hypothetical protein YP_670832.1 3114191 D 362663 CDS YP_670833.1 110643103 4188345 3114489..3115082 1 NC_008253.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3115082 4188345 ECP_2948 Escherichia coli 536 deoxyribonucleotide triphosphate pyrophosphatase YP_670833.1 3114489 D 362663 CDS YP_670834.1 110643104 4188346 3115075..3116211 1 NC_008253.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3116211 4188346 ECP_2949 Escherichia coli 536 coproporphyrinogen III oxidase YP_670834.1 3115075 D 362663 CDS YP_670835.1 110643105 4188347 complement(3116276..3117283) 1 NC_008253.1 hypothetical protein 3117283 4188347 ECP_2950 Escherichia coli 536 hypothetical protein YP_670835.1 3116276 R 362663 CDS YP_670836.1 110643106 4188348 complement(3117400..3118446) 1 NC_008253.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3118446 ansB 4188348 ansB Escherichia coli 536 L-asparaginase II YP_670836.1 3117400 R 362663 CDS YP_670837.1 110643107 4188349 complement(3118622..3119341) 1 NC_008253.1 hypothetical protein 3119341 4188349 ECP_2952 Escherichia coli 536 hypothetical protein YP_670837.1 3118622 R 362663 CDS YP_670838.1 110643108 4188350 complement(3119525..3119851) 1 NC_008253.1 hypothetical protein 3119851 4188350 ECP_2953 Escherichia coli 536 hypothetical protein YP_670838.1 3119525 R 362663 CDS YP_670839.1 110643109 4188351 complement(3119851..3120570) 1 NC_008253.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3120570 trmB 4188351 trmB Escherichia coli 536 tRNA (guanine-N(7)-)-methyltransferase YP_670839.1 3119851 R 362663 CDS YP_670840.1 110643110 4188352 3120731..3121783 1 NC_008253.1 adenine DNA glycosylase 3121783 4188352 ECP_2955 Escherichia coli 536 adenine DNA glycosylase YP_670840.1 3120731 D 362663 CDS YP_670841.1 110643111 4188353 3121811..3122086 1 NC_008253.1 hypothetical protein 3122086 4188353 ECP_2956 Escherichia coli 536 hypothetical protein YP_670841.1 3121811 D 362663 CDS YP_670842.1 110643112 4188354 3122148..3123230 1 NC_008253.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3123230 mltC 4188354 mltC Escherichia coli 536 murein transglycosylase C YP_670842.1 3122148 D 362663 CDS YP_670843.1 110643113 4191093 3123432..3124688 1 NC_008253.1 nucleoside permease NupG 3124688 4191093 ECP_2958 Escherichia coli 536 nucleoside permease NupG YP_670843.1 3123432 D 362663 CDS YP_670844.1 110643114 4191094 complement(3124737..3126872) 1 NC_008253.1 ornithine decarboxylase 3126872 4191094 ECP_2959 Escherichia coli 536 ornithine decarboxylase YP_670844.1 3124737 R 362663 CDS YP_670845.1 110643115 4191095 3127271..3127978 1 NC_008253.1 membrane protein YqgA 3127978 4191095 ECP_2960 Escherichia coli 536 membrane protein YqgA YP_670845.1 3127271 D 362663 CDS YP_670846.1 110643116 4191097 3128357..3129622 1 NC_008253.1 P4-type integrase 3129622 4191097 ECP_2962 Escherichia coli 536 P4-type integrase YP_670846.1 3128357 D 362663 CDS YP_670847.1 110643117 4191098 3129973..3130362 1 NC_008253.1 hypothetical protein 3130362 4191098 ECP_2963 Escherichia coli 536 hypothetical protein YP_670847.1 3129973 D 362663 CDS YP_670848.1 110643118 4191099 3130778..3130969 1 NC_008253.1 transposase-like protein 3130969 4191099 ECP_2964 Escherichia coli 536 transposase-like protein YP_670848.1 3130778 D 362663 CDS YP_670849.1 110643119 4191100 complement(3131239..3132021) 1 NC_008253.1 hypothetical protein 3132021 4191100 ECP_2965 Escherichia coli 536 hypothetical protein YP_670849.1 3131239 R 362663 CDS YP_670850.1 110643120 4191101 complement(3132074..3133066) 1 NC_008253.1 PixG protein 3133066 4191101 ECP_2966 Escherichia coli 536 PixG protein YP_670850.1 3132074 R 362663 CDS YP_670851.1 110643121 4191102 complement(3133089..3133607) 1 NC_008253.1 PixF protein 3133607 4191102 ECP_2967 Escherichia coli 536 PixF protein YP_670851.1 3133089 R 362663 CDS YP_670852.1 110643122 4191103 complement(3133691..3134254) 1 NC_008253.1 PixJ protein 3134254 4191103 ECP_2968 Escherichia coli 536 PixJ protein YP_670852.1 3133691 R 362663 CDS YP_670853.1 110643123 4191104 complement(3134291..3135163) 1 NC_008253.1 PixD protein 3135163 4191104 ECP_2969 Escherichia coli 536 PixD protein YP_670853.1 3134291 R 362663 CDS YP_670854.1 110643124 4191105 complement(3135091..3137661) 1 NC_008253.1 fimbrial usher protein PixC 3137661 4191105 ECP_2970 Escherichia coli 536 fimbrial usher protein PixC YP_670854.1 3135091 R 362663 CDS YP_670855.1 110643125 4191106 complement(3137722..3138309) 1 NC_008253.1 PixH protein 3138309 4191106 ECP_2971 Escherichia coli 536 PixH protein YP_670855.1 3137722 R 362663 CDS YP_670856.1 110643126 4191107 complement(3138395..3138928) 1 NC_008253.1 PixA protein 3138928 4191107 ECP_2972 Escherichia coli 536 PixA protein YP_670856.1 3138395 R 362663 CDS YP_670857.1 110643127 4191108 complement(3139664..3139888) 1 NC_008253.1 hypothetical protein 3139888 4191108 ECP_2973 Escherichia coli 536 hypothetical protein YP_670857.1 3139664 R 362663 CDS YP_670858.1 110643128 4191109 complement(3140041..3140535) 1 NC_008253.1 hypothetical protein 3140535 4191109 ECP_2974 Escherichia coli 536 hypothetical protein YP_670858.1 3140041 R 362663 CDS YP_670859.1 110643129 4191110 complement(3140894..3142150) 1 NC_008253.1 transport activator 3142150 4191110 ECP_2975 Escherichia coli 536 transport activator YP_670859.1 3140894 R 362663 CDS YP_670860.1 110643130 4191111 complement(3142131..3144140) 1 NC_008253.1 regulatory protein 3144140 4191111 ECP_2976 Escherichia coli 536 regulatory protein YP_670860.1 3142131 R 362663 CDS YP_670861.1 110643131 4188260 complement(3144137..3145408) 1 NC_008253.1 regulatory protein 3145408 4188260 ECP_2977 Escherichia coli 536 regulatory protein YP_670861.1 3144137 R 362663 CDS YP_670862.1 110643132 4188261 3145753..3147117 1 NC_008253.1 transporter protein 3147117 4188261 ECP_2978 Escherichia coli 536 transporter protein YP_670862.1 3145753 D 362663 CDS YP_670863.1 110643133 4188262 3147160..3147525 1 NC_008253.1 hypothetical protein 3147525 4188262 ECP_2979 Escherichia coli 536 hypothetical protein YP_670863.1 3147160 D 362663 CDS YP_670864.1 110643134 4188263 3147553..3147759 1 NC_008253.1 hypothetical protein 3147759 4188263 ECP_2980 Escherichia coli 536 hypothetical protein YP_670864.1 3147553 D 362663 CDS YP_670865.1 110643135 4188264 complement(3148065..3149078) 1 NC_008253.1 hypothetical protein 3149078 4188264 ECP_2981 Escherichia coli 536 hypothetical protein YP_670865.1 3148065 R 362663 CDS YP_670866.1 110643136 4188265 complement(3149090..3150406) 1 NC_008253.1 L-fucose permease 3150406 4188265 ECP_2982 Escherichia coli 536 L-fucose permease YP_670866.1 3149090 R 362663 CDS YP_670867.1 110643137 4188266 complement(3150434..3151354) 1 NC_008253.1 ribokinase sugar kinase 3151354 4188266 ECP_2983 Escherichia coli 536 ribokinase sugar kinase YP_670867.1 3150434 R 362663 CDS YP_670868.1 110643138 4188267 3151659..3152441 1 NC_008253.1 DeoR family transcriptional regulator 3152441 4188267 ECP_2984 Escherichia coli 536 DeoR family transcriptional regulator YP_670868.1 3151659 D 362663 CDS YP_670869.1 110643139 4188268 complement(3152542..3152658) 1 NC_008253.1 hypothetical protein 3152658 4188268 ECP_2985 Escherichia coli 536 hypothetical protein YP_670869.1 3152542 R 362663 CDS YP_670870.1 110643140 4188269 complement(3152669..3152869) 1 NC_008253.1 hypothetical protein 3152869 4188269 ECP_2986 Escherichia coli 536 hypothetical protein YP_670870.1 3152669 R 362663 CDS YP_670871.1 110643141 4188270 complement(3153510..3153731) 1 NC_008253.1 hypothetical protein 3153731 4188270 ECP_2987 Escherichia coli 536 hypothetical protein YP_670871.1 3153510 R 362663 CDS YP_670872.1 110643142 4188271 complement(3153836..3154369) 1 NC_008253.1 hypothetical protein 3154369 4188271 ECP_2988 Escherichia coli 536 hypothetical protein YP_670872.1 3153836 R 362663 CDS YP_670873.1 110643143 4188272 complement(3154363..3155202) 1 NC_008253.1 transposase (orfB) 3155202 4188272 ECP_2989 Escherichia coli 536 transposase (orfB) YP_670873.1 3154363 R 362663 CDS YP_670874.1 110643144 4188273 complement(3155229..3155531) 1 NC_008253.1 transposase 3155531 4188273 ECP_2990 Escherichia coli 536 transposase YP_670874.1 3155229 R 362663 CDS YP_670875.1 110643145 4188274 complement(3155676..3155873) 1 NC_008253.1 hypothetical protein 3155873 4188274 ECP_2991 Escherichia coli 536 hypothetical protein YP_670875.1 3155676 R 362663 CDS YP_670876.1 110643146 4188275 complement(3156120..3156545) 1 NC_008253.1 hypothetical protein 3156545 4188275 ECP_2992 Escherichia coli 536 hypothetical protein YP_670876.1 3156120 R 362663 CDS YP_670877.1 110643147 4188276 complement(3156542..3156925) 1 NC_008253.1 hypothetical protein 3156925 4188276 ECP_2993 Escherichia coli 536 hypothetical protein YP_670877.1 3156542 R 362663 CDS YP_670878.1 110643148 4188277 3156995..3157216 1 NC_008253.1 hypothetical protein 3157216 4188277 ECP_2994 Escherichia coli 536 hypothetical protein YP_670878.1 3156995 D 362663 CDS YP_670879.1 110643149 4188278 3157431..3158453 1 NC_008253.1 transposase for insertion sequence IS100 3158453 4188278 ECP_2995 Escherichia coli 536 transposase for insertion sequence IS100 YP_670879.1 3157431 D 362663 CDS YP_670880.1 110643150 4188296 3158453..3159232 1 NC_008253.1 transposase/IS protein 3159232 4188296 ECP_2996 Escherichia coli 536 transposase/IS protein YP_670880.1 3158453 D 362663 CDS YP_670881.1 110643151 4188297 complement(3159276..3159854) 1 NC_008253.1 hypothetical protein 3159854 4188297 ECP_2997 Escherichia coli 536 hypothetical protein YP_670881.1 3159276 R 362663 CDS YP_670882.1 110643152 4188298 complement(3160086..3160472) 1 NC_008253.1 hemolysin expression modulating protein 3160472 4188298 ECP_2998 Escherichia coli 536 hemolysin expression modulating protein YP_670882.1 3160086 R 362663 CDS YP_670883.1 110643153 4188299 3161311..3162102 1 NC_008253.1 hypothetical protein 3162102 4188299 ECP_2999 Escherichia coli 536 hypothetical protein YP_670883.1 3161311 D 362663 CDS YP_670884.1 110643154 4188300 3162486..3162692 1 NC_008253.1 regulatory protein 3162692 4188300 ECP_3000 Escherichia coli 536 regulatory protein YP_670884.1 3162486 D 362663 CDS YP_670885.1 110643155 4188301 3162786..3163388 1 NC_008253.1 hypothetical protein 3163388 4188301 ECP_3001 Escherichia coli 536 hypothetical protein YP_670885.1 3162786 D 362663 CDS YP_670886.1 110643156 4188302 complement(3163449..3163763) 1 NC_008253.1 hypothetical protein 3163763 4188302 ECP_3002 Escherichia coli 536 hypothetical protein YP_670886.1 3163449 R 362663 CDS YP_670887.1 110643157 4188303 3164148..3164360 1 NC_008253.1 hypothetical protein 3164360 4188303 ECP_3003 Escherichia coli 536 hypothetical protein YP_670887.1 3164148 D 362663 CDS YP_670888.1 110643158 4188304 3164407..3164709 1 NC_008253.1 hypothetical protein 3164709 4188304 ECP_3004 Escherichia coli 536 hypothetical protein YP_670888.1 3164407 D 362663 CDS YP_670889.1 110643159 4188305 3165098..3165310 1 NC_008253.1 hypothetical protein 3165310 4188305 ECP_3005 Escherichia coli 536 hypothetical protein YP_670889.1 3165098 D 362663 CDS YP_670890.1 110643160 4188306 3165831..3166457 1 NC_008253.1 hypothetical protein 3166457 4188306 ECP_3006 Escherichia coli 536 hypothetical protein YP_670890.1 3165831 D 362663 CDS YP_670891.1 110643161 4188307 complement(3166597..3167271) 1 NC_008253.1 hypothetical protein 3167271 4188307 ECP_3007 Escherichia coli 536 hypothetical protein YP_670891.1 3166597 R 362663 CDS YP_670892.1 110643162 4188308 3167566..3168438 1 NC_008253.1 hypothetical protein 3168438 4188308 ECP_3008 Escherichia coli 536 hypothetical protein YP_670892.1 3167566 D 362663 CDS YP_670893.1 110643163 4188309 3168808..3171654 1 NC_008253.1 autotransporter 3171654 4188309 ECP_3009 Escherichia coli 536 autotransporter YP_670893.1 3168808 D 362663 CDS YP_670894.1 110643164 4188310 3171725..3171958 1 NC_008253.1 hypothetical protein 3171958 4188310 ECP_3010 Escherichia coli 536 hypothetical protein YP_670894.1 3171725 D 362663 CDS YP_670895.1 110643165 4188311 3172049..3172867 1 NC_008253.1 hypothetical protein 3172867 4188311 ECP_3011 Escherichia coli 536 hypothetical protein YP_670895.1 3172049 D 362663 CDS YP_670896.1 110643166 4188312 3172959..3173444 1 NC_008253.1 hypothetical protein 3173444 4188312 ECP_3012 Escherichia coli 536 hypothetical protein YP_670896.1 3172959 D 362663 CDS YP_670897.1 110643167 4188313 3173460..3173936 1 NC_008253.1 radC-like protein YeeS 3173936 4188313 ECP_3013 Escherichia coli 536 radC-like protein YeeS YP_670897.1 3173460 D 362663 CDS YP_670898.1 110643168 4188314 3174005..3174226 1 NC_008253.1 hypothetical protein 3174226 4188314 ECP_3014 Escherichia coli 536 hypothetical protein YP_670898.1 3174005 D 362663 CDS YP_670899.1 110643169 4188315 3174240..3174668 1 NC_008253.1 hypothetical protein 3174668 4188315 ECP_3015 Escherichia coli 536 hypothetical protein YP_670899.1 3174240 D 362663 CDS YP_670900.1 110643170 4189430 3174758..3175135 1 NC_008253.1 hypothetical protein 3175135 4189430 ECP_3016 Escherichia coli 536 hypothetical protein YP_670900.1 3174758 D 362663 CDS YP_670901.1 110643171 4189431 3175132..3175620 1 NC_008253.1 hypothetical protein 3175620 4189431 ECP_3017 Escherichia coli 536 hypothetical protein YP_670901.1 3175132 D 362663 CDS YP_670902.1 110643172 4189432 3175587..3175829 1 NC_008253.1 hypothetical protein 3175829 4189432 ECP_3018 Escherichia coli 536 hypothetical protein YP_670902.1 3175587 D 362663 CDS YP_670903.1 110643173 4189433 3175914..3176756 1 NC_008253.1 hypothetical protein 3176756 4189433 ECP_3019 Escherichia coli 536 hypothetical protein YP_670903.1 3175914 D 362663 CDS YP_670904.1 110643174 4189434 3178080..3179063 1 NC_008253.1 polysialic acid capsule expression protein KpsF 3179063 4189434 ECP_3020 Escherichia coli 536 polysialic acid capsule expression protein KpsF YP_670904.1 3178080 D 362663 CDS YP_670905.1 110643175 4189435 3179135..3180283 1 NC_008253.1 capsule polysaccharide export inner-membrane protein KpsE 3180283 4189435 ECP_3021 Escherichia coli 536 capsule polysaccharide export inner-membrane protein KpsE YP_670905.1 3179135 D 362663 CDS YP_670906.1 110643176 4189436 3180307..3181983 1 NC_008253.1 polysialic acid transport protein KpsD precursor 3181983 4189436 ECP_3022 Escherichia coli 536 polysialic acid transport protein KpsD precursor YP_670906.1 3180307 D 362663 CDS YP_670907.1 110643177 4189437 3181993..3182733 1 NC_008253.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3182733 4189437 ECP_3023 Escherichia coli 536 3-deoxy-manno-octulosonate cytidylyltransferase YP_670907.1 3181993 D 362663 CDS YP_670908.1 110643178 4189438 3182730..3184178 1 NC_008253.1 capsule polysaccharide export protein KpsC 3184178 4189438 ECP_3024 Escherichia coli 536 capsule polysaccharide export protein KpsC YP_670908.1 3182730 D 362663 CDS YP_670909.1 110643179 4189439 3184216..3184593 1 NC_008253.1 hypothetical protein 3184593 4189439 ECP_3025 Escherichia coli 536 hypothetical protein YP_670909.1 3184216 D 362663 CDS YP_670910.1 110643180 4189440 3184702..3185253 1 NC_008253.1 hypothetical protein 3185253 4189440 ECP_3026 Escherichia coli 536 hypothetical protein YP_670910.1 3184702 D 362663 CDS YP_670911.1 110643181 4189441 complement(3185408..3186658) 1 NC_008253.1 capsule polysaccharide export protein KpsS 3186658 4189441 ECP_3027 Escherichia coli 536 capsule polysaccharide export protein KpsS YP_670911.1 3185408 R 362663 CDS YP_670912.1 110643182 4189442 complement(3186695..3188824) 1 NC_008253.1 capsule export protein KpsC 3188824 4189442 ECP_3028 Escherichia coli 536 capsule export protein KpsC YP_670912.1 3186695 R 362663 CDS YP_670913.1 110643183 4189443 complement(3189178..3190116) 1 NC_008253.1 hypothetical protein 3190116 4189443 ECP_3029 Escherichia coli 536 hypothetical protein YP_670913.1 3189178 R 362663 CDS YP_670914.1 110643184 4189444 complement(3190094..3190381) 1 NC_008253.1 hypothetical protein 3190381 4189444 ECP_3030 Escherichia coli 536 hypothetical protein YP_670914.1 3190094 R 362663 CDS YP_670915.1 110643185 4189445 complement(3190414..3191052) 1 NC_008253.1 hypothetical protein 3191052 4189445 ECP_3031 Escherichia coli 536 hypothetical protein YP_670915.1 3190414 R 362663 CDS YP_670916.1 110643186 4189446 complement(3191049..3192008) 1 NC_008253.1 hypothetical protein 3192008 4189446 ECP_3032 Escherichia coli 536 hypothetical protein YP_670916.1 3191049 R 362663 CDS YP_670917.1 110643187 4189447 complement(3192005..3192994) 1 NC_008253.1 hypothetical protein 3192994 4189447 ECP_3033 Escherichia coli 536 hypothetical protein YP_670917.1 3192005 R 362663 CDS YP_670918.1 110643188 4189448 complement(3192991..3193881) 1 NC_008253.1 glycosyltransferase 3193881 4189448 ECP_3034 Escherichia coli 536 glycosyltransferase YP_670918.1 3192991 R 362663 CDS YP_670919.1 110643189 4188355 complement(3194876..3195544) 1 NC_008253.1 polysialic acid transport ATP-binding protein KpsT 3195544 4188355 ECP_3035 Escherichia coli 536 polysialic acid transport ATP-binding protein KpsT YP_670919.1 3194876 R 362663 CDS YP_670920.1 110643190 4188356 complement(3195541..3196317) 1 NC_008253.1 polysialic acid transport protein KpsM 3196317 4188356 ECP_3036 Escherichia coli 536 polysialic acid transport protein KpsM YP_670920.1 3195541 R 362663 CDS YP_670921.1 110643191 4188357 complement(3197373..3197909) 1 NC_008253.1 general secretion pathway protein YghD 3197909 4188357 ECP_3037 Escherichia coli 536 general secretion pathway protein YghD YP_670921.1 3197373 R 362663 CDS YP_670922.2 162138276 4188358 complement(3197911..3198771) 1 NC_008253.1 similar to general secretory pathway protein L; GspL-like protein 3198771 4188358 ECP_3038 Escherichia coli 536 GspL-like protein YP_670922.2 3197911 R 362663 CDS YP_670923.1 110643193 4188359 complement(3199086..3200063) 1 NC_008253.1 type II secretion protein GspK 3200063 4188359 ECP_3039 Escherichia coli 536 type II secretion protein GspK YP_670923.1 3199086 R 362663 CDS YP_670924.1 110643194 4188360 complement(3200060..3200665) 1 NC_008253.1 type II secretion protein GspJ 3200665 4188360 ECP_3040 Escherichia coli 536 type II secretion protein GspJ YP_670924.1 3200060 R 362663 CDS YP_670925.1 110643195 4188361 complement(3200662..3201033) 1 NC_008253.1 type II secretion protein GspI 3201033 4188361 ECP_3041 Escherichia coli 536 type II secretion protein GspI YP_670925.1 3200662 R 362663 CDS YP_670926.1 110643196 4188362 complement(3201030..3201593) 1 NC_008253.1 type II secretion protein GspH 3201593 4188362 ECP_3042 Escherichia coli 536 type II secretion protein GspH YP_670926.1 3201030 R 362663 CDS YP_670927.1 110643197 4188363 complement(3201597..3202052) 1 NC_008253.1 type II secretion protein 3202052 4188363 ECP_3043 Escherichia coli 536 type II secretion protein YP_670927.1 3201597 R 362663 CDS YP_670928.1 110643198 4188364 complement(3202069..3203292) 1 NC_008253.1 type II secretion protein GspF 3203292 4188364 ECP_3044 Escherichia coli 536 type II secretion protein GspF YP_670928.1 3202069 R 362663 CDS YP_670929.1 110643199 4188365 complement(3203292..3204785) 1 NC_008253.1 type II secretion protein GspE 3204785 4188365 ECP_3045 Escherichia coli 536 type II secretion protein GspE YP_670929.1 3203292 R 362663 CDS YP_670930.1 110643200 4188366 complement(3204785..3206845) 1 NC_008253.1 type II secretion protein GspD 3206845 4188366 ECP_3046 Escherichia coli 536 type II secretion protein GspD YP_670930.1 3204785 R 362663 CDS YP_670931.1 110643201 4188367 complement(3206875..3207834) 1 NC_008253.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 3207834 4188367 ECP_3047 Escherichia coli 536 type II secretion protein GspC YP_670931.1 3206875 R 362663 CDS YP_670932.1 110643202 4188368 complement(3207852..3208262) 1 NC_008253.1 lipoprotein 3208262 4188368 ECP_3048 Escherichia coli 536 lipoprotein YP_670932.1 3207852 R 362663 CDS YP_670933.1 110643203 4188369 complement(3208328..3209137) 1 NC_008253.1 prepilin peptidase 3209137 4188369 ECP_3049 Escherichia coli 536 prepilin peptidase YP_670933.1 3208328 R 362663 CDS YP_670934.1 110643204 4188370 complement(3209277..3213842) 1 NC_008253.1 lipoprotein AcfD 3213842 4188370 ECP_3050 Escherichia coli 536 lipoprotein AcfD YP_670934.1 3209277 R 362663 CDS YP_670935.1 110643205 4188371 3213993..3214193 1 NC_008253.1 hypothetical protein 3214193 4188371 ECP_3051 Escherichia coli 536 hypothetical protein YP_670935.1 3213993 D 362663 CDS YP_670936.1 110643206 4188372 complement(3214327..3216009) 1 NC_008253.1 glycolate transporter 3216009 4188372 ECP_3052 Escherichia coli 536 glycolate transporter YP_670936.1 3214327 R 362663 CDS YP_670937.1 110643207 4188373 complement(3216364..3218535) 1 NC_008253.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3218535 4188373 ECP_3053 Escherichia coli 536 malate synthase G YP_670937.1 3216364 R 362663 CDS YP_670938.1 110643208 4188374 complement(3218557..3218961) 1 NC_008253.1 hypothetical protein 3218961 4188374 ECP_3054 Escherichia coli 536 hypothetical protein YP_670938.1 3218557 R 362663 CDS YP_670939.1 110643209 4189143 complement(3218966..3220189) 1 NC_008253.1 glycolate oxidase iron-sulfur subunit 3220189 glcF 4189143 glcF Escherichia coli 536 glycolate oxidase iron-sulfur subunit YP_670939.1 3218966 R 362663 CDS YP_670940.1 110643210 4189144 complement(3220200..3221252) 1 NC_008253.1 glycolate oxidase FAD binding subunit 3221252 glcE 4189144 glcE Escherichia coli 536 glycolate oxidase FAD binding subunit YP_670940.1 3220200 R 362663 CDS YP_670941.1 110643211 4189145 complement(3221252..3222751) 1 NC_008253.1 glycolate oxidase subunit GlcD 3222751 4189145 ECP_3057 Escherichia coli 536 glycolate oxidase subunit GlcD YP_670941.1 3221252 R 362663 CDS YP_670942.1 110643212 4189146 3223002..3223766 1 NC_008253.1 DNA-binding transcriptional regulator GlcC 3223766 4189146 ECP_3058 Escherichia coli 536 DNA-binding transcriptional regulator GlcC YP_670942.1 3223002 D 362663 CDS YP_670943.1 110643213 4189147 complement(3223773..3224915) 1 NC_008253.1 hypothetical protein 3224915 4189147 ECP_3059 Escherichia coli 536 hypothetical protein YP_670943.1 3223773 R 362663 CDS YP_670944.1 110643214 4189148 3225287..3227008 1 NC_008253.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3227008 4189148 ECP_3060 Escherichia coli 536 acyl-CoA synthetase YP_670944.1 3225287 D 362663 CDS YP_670945.1 110643215 4189149 3227005..3227919 1 NC_008253.1 hypothetical protein 3227919 4189149 ECP_3061 Escherichia coli 536 hypothetical protein YP_670945.1 3227005 D 362663 CDS YP_670946.1 110643216 4189150 3227972..3228199 1 NC_008253.1 acyl carrier protein 3228199 4189150 ECP_3062 Escherichia coli 536 acyl carrier protein YP_670946.1 3227972 D 362663 CDS YP_670947.1 110643217 4189151 3228199..3229371 1 NC_008253.1 aminotransferase 3229371 4189151 ECP_3063 Escherichia coli 536 aminotransferase YP_670947.1 3228199 D 362663 CDS YP_670948.1 110643218 4189152 complement(3229406..3230485) 1 NC_008253.1 permease 3230485 4189152 ECP_3064 Escherichia coli 536 permease YP_670948.1 3229406 R 362663 CDS YP_670949.1 110643219 4189153 complement(3230482..3231552) 1 NC_008253.1 permease 3231552 4189153 ECP_3065 Escherichia coli 536 permease YP_670949.1 3230482 R 362663 CDS YP_670950.1 110643220 4189154 complement(3231583..3232143) 1 NC_008253.1 hypothetical protein 3232143 4189154 ECP_3066 Escherichia coli 536 hypothetical protein YP_670950.1 3231583 R 362663 CDS YP_670951.1 110643221 4189155 complement(3232155..3232979) 1 NC_008253.1 hypothetical protein 3232979 4189155 ECP_3067 Escherichia coli 536 hypothetical protein YP_670951.1 3232155 R 362663 CDS YP_670952.1 110643222 4189156 complement(3232979..3234328) 1 NC_008253.1 hypothetical protein 3234328 4189156 ECP_3068 Escherichia coli 536 hypothetical protein YP_670952.1 3232979 R 362663 CDS YP_670953.1 110643223 4189157 complement(3234374..3235132) 1 NC_008253.1 ATP-binding protein YghR 3235132 4189157 ECP_3069 Escherichia coli 536 ATP-binding protein YghR YP_670953.1 3234374 R 362663 CDS YP_670954.1 110643224 4189158 complement(3235164..3235862) 1 NC_008253.1 ATP-binding protein YghS 3235862 4189158 ECP_3070 Escherichia coli 536 ATP-binding protein YghS YP_670954.1 3235164 R 362663 CDS YP_670955.1 110643225 4189159 3236051..3236743 1 NC_008253.1 ATP-binding protein YghT 3236743 4189159 ECP_3071 Escherichia coli 536 ATP-binding protein YghT YP_670955.1 3236051 D 362663 CDS YP_670956.1 110643226 4189160 complement(3236792..3238291) 1 NC_008253.1 inorganic phosphate transporter 3238291 4189160 ECP_3072 Escherichia coli 536 inorganic phosphate transporter YP_670956.1 3236792 R 362663 CDS YP_670957.1 110643227 4189161 complement(3238583..3240442) 1 NC_008253.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3240442 4189161 ECP_3073 Escherichia coli 536 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_670957.1 3238583 R 362663 CDS YP_670958.1 110643228 4190498 3240647..3240976 1 NC_008253.1 hypothetical protein 3240976 4190498 ECP_3074 Escherichia coli 536 hypothetical protein YP_670958.1 3240647 D 362663 CDS YP_670959.1 110643229 4190499 3240930..3241514 1 NC_008253.1 hypothetical protein 3241514 4190499 ECP_3075 Escherichia coli 536 hypothetical protein YP_670959.1 3240930 D 362663 CDS YP_670960.1 110643230 4190500 complement(3241584..3241832) 1 NC_008253.1 hydrogenase 2 accessory protein HypG 3241832 4190500 ECP_3076 Escherichia coli 536 hydrogenase 2 accessory protein HypG YP_670960.1 3241584 R 362663 CDS YP_670961.1 110643231 4190501 complement(3241845..3242186) 1 NC_008253.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3242186 4190501 ECP_3077 Escherichia coli 536 hydrogenase nickel incorporation protein HybF YP_670961.1 3241845 R 362663 CDS YP_670962.1 110643232 4190502 complement(3242179..3242667) 1 NC_008253.1 hydrogenase 2-specific chaperone 3242667 4190502 ECP_3078 Escherichia coli 536 hydrogenase 2-specific chaperone YP_670962.1 3242179 R 362663 CDS YP_670963.1 110643233 4190503 complement(3242660..3243154) 1 NC_008253.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3243154 hybD 4190503 hybD Escherichia coli 536 hydrogenase 2 maturation endopeptidase YP_670963.1 3242660 R 362663 CDS YP_670964.1 110643234 4190504 complement(3243154..3244857) 1 NC_008253.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3244857 4190504 ECP_3080 Escherichia coli 536 hydrogenase 2 large subunit YP_670964.1 3243154 R 362663 CDS YP_670965.1 110643235 4190505 complement(3244854..3246032) 1 NC_008253.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3246032 4190505 ECP_3081 Escherichia coli 536 hydrogenase 2 b cytochrome subunit YP_670965.1 3244854 R 362663 CDS YP_670966.1 110643236 4190506 complement(3246022..3247008) 1 NC_008253.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3247008 4190506 ECP_3082 Escherichia coli 536 hydrogenase 2 protein HybA YP_670966.1 3246022 R 362663 CDS YP_670967.1 110643237 4190507 complement(3247011..3248129) 1 NC_008253.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3248129 4190507 ECP_3083 Escherichia coli 536 hydrogenase 2 small subunit YP_670967.1 3247011 R 362663 CDS YP_670968.1 110643238 4190508 complement(3248318..3248605) 1 NC_008253.1 hypothetical protein 3248605 4190508 ECP_3084 Escherichia coli 536 hypothetical protein YP_670968.1 3248318 R 362663 CDS YP_670969.1 110643239 4190509 complement(3248724..3249614) 1 NC_008253.1 hydrolase 3249614 4190509 ECP_3085 Escherichia coli 536 hydrolase YP_670969.1 3248724 R 362663 CDS YP_670970.1 110643240 4190510 3249768..3250808 1 NC_008253.1 aldo/keto reductase 3250808 4190510 ECP_3086 Escherichia coli 536 aldo/keto reductase YP_670970.1 3249768 D 362663 CDS YP_670971.1 110643241 4190511 complement(3250848..3251342) 1 NC_008253.1 hypothetical protein 3251342 4190511 ECP_3087 Escherichia coli 536 hypothetical protein YP_670971.1 3250848 R 362663 CDS YP_670972.1 110643242 4190512 3251533..3252417 1 NC_008253.1 oxidoreductase 3252417 4190512 ECP_3088 Escherichia coli 536 oxidoreductase YP_670972.1 3251533 D 362663 CDS YP_670973.1 110643243 4190513 complement(3252456..3252881) 1 NC_008253.1 tonB-dependent uptake of B colicins; membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3252881 4190513 ECP_3089 Escherichia coli 536 biopolymer transport protein ExbD YP_670973.1 3252456 R 362663 CDS YP_670974.1 110643244 4190514 complement(3252888..3253607) 1 NC_008253.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3253607 4190514 ECP_3090 Escherichia coli 536 biopolymer transport protein ExbB YP_670974.1 3252888 R 362663 CDS YP_670975.1 110643245 4190515 3253874..3255061 1 NC_008253.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3255061 4190515 ECP_3091 Escherichia coli 536 cystathionine beta-lyase YP_670975.1 3253874 D 362663 CDS YP_670976.1 110643246 4190516 3255201..3255860 1 NC_008253.1 hypothetical protein 3255860 4190516 ECP_3092 Escherichia coli 536 hypothetical protein YP_670976.1 3255201 D 362663 CDS YP_670977.1 110643247 4190517 complement(3255900..3256967) 1 NC_008253.1 transcriptional regulator YqhC 3256967 4190517 ECP_3093 Escherichia coli 536 transcriptional regulator YqhC YP_670977.1 3255900 R 362663 CDS YP_670978.1 110643248 4190596 3256993..3258156 1 NC_008253.1 alcohol dehydrogenase 3258156 4190596 ECP_3094 Escherichia coli 536 alcohol dehydrogenase YP_670978.1 3256993 D 362663 CDS YP_670979.1 110643249 4190597 3258261..3259088 1 NC_008253.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3259088 dkgA 4190597 dkgA Escherichia coli 536 2,5-diketo-D-gluconate reductase A YP_670979.1 3258261 D 362663 CDS YP_670980.1 110643250 4190598 3259288..3260214 1 NC_008253.1 hypothetical protein 3260214 4190598 ECP_3096 Escherichia coli 536 hypothetical protein YP_670980.1 3259288 D 362663 CDS YP_670981.1 110643251 4190599 3260265..3260522 1 NC_008253.1 outer membrane lipoprotein 3260522 4190599 ECP_3097 Escherichia coli 536 outer membrane lipoprotein YP_670981.1 3260265 D 362663 CDS YP_670982.1 110643252 4190600 complement(3260564..3262783) 1 NC_008253.1 hypothetical protein 3262783 4190600 ECP_3098 Escherichia coli 536 hypothetical protein YP_670982.1 3260564 R 362663 CDS YP_670983.1 110643253 4190601 3263035..3263784 1 NC_008253.1 GntR family transcriptional regulator 3263784 4190601 ECP_3099 Escherichia coli 536 GntR family transcriptional regulator YP_670983.1 3263035 D 362663 CDS YP_670984.1 110643254 4190602 3264107..3265579 1 NC_008253.1 mannitol dehydrogenase 3265579 4190602 ECP_3100 Escherichia coli 536 mannitol dehydrogenase YP_670984.1 3264107 D 362663 CDS YP_670985.1 110643255 4190603 3265576..3266592 1 NC_008253.1 zinc-binding dehydrogenase 3266592 4190603 ECP_3101 Escherichia coli 536 zinc-binding dehydrogenase YP_670985.1 3265576 D 362663 CDS YP_670986.1 110643256 4190604 3266603..3267613 1 NC_008253.1 malate/L-lactate dehydrogenase 3267613 4190604 ECP_3102 Escherichia coli 536 malate/L-lactate dehydrogenase YP_670986.1 3266603 D 362663 CDS YP_670987.1 110643257 4190605 3267686..3268669 1 NC_008253.1 C4-dicarboxylate transport system binding protein 3268669 4190605 ECP_3103 Escherichia coli 536 C4-dicarboxylate transport system binding protein YP_670987.1 3267686 D 362663 CDS YP_670988.1 110643258 4190606 3268711..3269193 1 NC_008253.1 C4-dicarboxylate transport system 3269193 4190606 ECP_3104 Escherichia coli 536 C4-dicarboxylate transport system YP_670988.1 3268711 D 362663 CDS YP_670989.1 110643259 4190607 3269204..3270508 1 NC_008253.1 C4-dicarboxylate transport system 3270508 4190607 ECP_3105 Escherichia coli 536 C4-dicarboxylate transport system YP_670989.1 3269204 D 362663 CDS YP_670990.1 110643260 4190608 complement(3270579..3271991) 1 NC_008253.1 repressor protein for FtsI 3271991 4190608 ECP_3106 Escherichia coli 536 repressor protein for FtsI YP_670990.1 3270579 R 362663 CDS YP_670991.1 110643261 4190609 complement(3272066..3272803) 1 NC_008253.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 3272803 4190609 ECP_3107 Escherichia coli 536 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_670991.1 3272066 R 362663 CDS YP_670992.1 110643262 4190610 complement(3273037..3275295) 1 NC_008253.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3275295 4190610 ECP_3108 Escherichia coli 536 DNA topoisomerase IV subunit A YP_670992.1 3273037 R 362663 CDS YP_670993.1 110643263 4190611 complement(3275433..3277040) 1 NC_008253.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; hypothetical protein 3277040 4190611 ECP_3109 Escherichia coli 536 hypothetical protein YP_670993.1 3275433 R 362663 CDS YP_670994.1 110643264 4190612 complement(3277149..3277631) 1 NC_008253.1 AraC family transcriptional regulator 3277631 4190612 ECP_3110 Escherichia coli 536 AraC family transcriptional regulator YP_670994.1 3277149 R 362663 CDS YP_670995.1 110643265 4190613 complement(3277684..3278076) 1 NC_008253.1 protein YgiW 3278076 4190613 ECP_3111 Escherichia coli 536 protein YgiW YP_670995.1 3277684 R 362663 CDS YP_670996.1 110643266 4190614 3278228..3278887 1 NC_008253.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3278887 4190614 ECP_3112 Escherichia coli 536 DNA-binding transcriptional regulator QseB YP_670996.1 3278228 D 362663 CDS YP_670997.1 110643267 4190673 3278884..3280233 1 NC_008253.1 sensor protein QseC 3280233 4190673 ECP_3113 Escherichia coli 536 sensor protein QseC YP_670997.1 3278884 D 362663 CDS YP_670998.1 110643268 4190674 3280343..3280924 1 NC_008253.1 modulator of drug activity B 3280924 4190674 ECP_3114 Escherichia coli 536 modulator of drug activity B YP_670998.1 3280343 D 362663 CDS YP_670999.1 110643269 4190675 3280955..3281269 1 NC_008253.1 hypothetical protein 3281269 4190675 ECP_3115 Escherichia coli 536 hypothetical protein YP_670999.1 3280955 D 362663 CDS YP_671000.1 110643270 4190676 complement(3281314..3282201) 1 NC_008253.1 phosphosugar isomerase 3282201 4190676 ECP_3116 Escherichia coli 536 phosphosugar isomerase YP_671000.1 3281314 R 362663 CDS YP_671001.1 110643271 4190677 complement(3282198..3283145) 1 NC_008253.1 iron ABC transporter substrate-binding protein 3283145 4190677 ECP_3117 Escherichia coli 536 iron ABC transporter substrate-binding protein YP_671001.1 3282198 R 362663 CDS YP_671002.1 110643272 4190678 complement(3283156..3284205) 1 NC_008253.1 iron ABC transporter permease 3284205 4190678 ECP_3118 Escherichia coli 536 iron ABC transporter permease YP_671002.1 3283156 R 362663 CDS YP_671003.1 110643273 4190679 complement(3284202..3285185) 1 NC_008253.1 iron ABC transporter permease 3285185 4190679 ECP_3119 Escherichia coli 536 iron ABC transporter permease YP_671003.1 3284202 R 362663 CDS YP_671004.1 110643274 4190680 complement(3285182..3285991) 1 NC_008253.1 ferric enterobactin transport ATP-binding protein FepC 3285991 4190680 ECP_3120 Escherichia coli 536 ferric enterobactin transport ATP-binding protein FepC YP_671004.1 3285182 R 362663 CDS YP_671005.1 110643275 4190681 3286365..3288506 1 NC_008253.1 iron compound receptor 3288506 4190681 ECP_3121 Escherichia coli 536 iron compound receptor YP_671005.1 3286365 D 362663 CDS YP_671006.1 110643276 4190682 complement(3288570..3290462) 1 NC_008253.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3290462 4190682 ECP_3122 Escherichia coli 536 DNA topoisomerase IV subunit B YP_671006.1 3288570 R 362663 CDS YP_671007.1 110643277 4190683 complement(3290491..3291072) 1 NC_008253.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 3291072 4190683 ECP_3123 Escherichia coli 536 esterase YP_671007.1 3290491 R 362663 CDS YP_671008.1 110643278 4190684 complement(3291072..3291899) 1 NC_008253.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 3291899 4190684 ECP_3124 Escherichia coli 536 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_671008.1 3291072 R 362663 CDS YP_671009.1 110643279 4190685 complement(3291924..3292346) 1 NC_008253.1 hypothetical protein 3292346 4190685 ECP_3125 Escherichia coli 536 hypothetical protein YP_671009.1 3291924 R 362663 CDS YP_671010.1 110643280 4190686 complement(3292347..3292976) 1 NC_008253.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 3292976 nudF 4190686 nudF Escherichia coli 536 ADP-ribose pyrophosphatase YP_671010.1 3292347 R 362663 CDS YP_671011.1 110643281 4190687 3293181..3294662 1 NC_008253.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3294662 tolC 4190687 tolC Escherichia coli 536 outer membrane channel protein YP_671011.1 3293181 D 362663 CDS YP_671012.1 110643282 4190688 3294777..3295481 1 NC_008253.1 hypothetical protein 3295481 4190688 ECP_3128 Escherichia coli 536 hypothetical protein YP_671012.1 3294777 D 362663 CDS YP_671013.1 110643283 4190689 3295487..3296647 1 NC_008253.1 glutathionylspermidine synthase 3296647 4190689 ECP_3129 Escherichia coli 536 glutathionylspermidine synthase YP_671013.1 3295487 D 362663 CDS YP_671014.1 110643284 4190690 3297132..3298928 1 NC_008253.1 arylsulfate sulfotransferase 3298928 4190690 ECP_3130 Escherichia coli 536 arylsulfate sulfotransferase YP_671014.1 3297132 D 362663 CDS YP_671015.1 110643285 4190691 3298946..3299614 1 NC_008253.1 thiol-disulfide isomerase and thioredoxin 3299614 4190691 ECP_3131 Escherichia coli 536 thiol-disulfide isomerase and thioredoxin YP_671015.1 3298946 D 362663 CDS YP_671016.1 110643286 4190692 3299644..3300300 1 NC_008253.1 disulfide oxidoreductase 3300300 4190692 ECP_3132 Escherichia coli 536 disulfide oxidoreductase YP_671016.1 3299644 D 362663 CDS YP_671017.1 110643287 4188550 complement(3300346..3301161) 1 NC_008253.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3301161 4188550 ECP_3133 Escherichia coli 536 hypothetical protein YP_671017.1 3300346 R 362663 CDS YP_671018.1 110643288 4188551 3301277..3302050 1 NC_008253.1 zinc transporter ZupT 3302050 4188551 ECP_3134 Escherichia coli 536 zinc transporter ZupT YP_671018.1 3301277 D 362663 CDS YP_671019.1 110643289 4188552 complement(3302108..3302278) 1 NC_008253.1 hypothetical protein 3302278 4188552 ECP_3135 Escherichia coli 536 hypothetical protein YP_671019.1 3302108 R 362663 CDS YP_671020.1 110643290 4188553 complement(3302540..3303193) 1 NC_008253.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3303193 ribB 4188553 ribB Escherichia coli 536 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_671020.1 3302540 R 362663 CDS YP_671021.1 110643291 4188554 3303568..3303867 1 NC_008253.1 hypothetical protein 3303867 4188554 ECP_3137 Escherichia coli 536 hypothetical protein YP_671021.1 3303568 D 362663 CDS YP_671022.1 110643292 4188555 complement(3303902..3304102) 1 NC_008253.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3304102 4188555 ECP_3138 Escherichia coli 536 glycogen synthesis protein GlgS YP_671022.1 3303902 R 362663 CDS YP_671023.1 110643293 4188556 3304371..3305000 1 NC_008253.1 membrane protein YqiJ 3305000 4188556 ECP_3139 Escherichia coli 536 membrane protein YqiJ YP_671023.1 3304371 D 362663 CDS YP_671024.1 110643294 4188557 3305027..3306688 1 NC_008253.1 membrane protein YqiK 3306688 4188557 ECP_3140 Escherichia coli 536 membrane protein YqiK YP_671024.1 3305027 D 362663 CDS YP_671025.1 110643295 4188558 complement(3307106..3308539) 1 NC_008253.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3308539 4188558 ECP_3141 Escherichia coli 536 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_671025.1 3307106 R 362663 CDS YP_671026.1 110643296 4188559 complement(3308587..3310758) 1 NC_008253.1 glutamate-ammonia-ligase adenylyltransferase 3310758 4188559 ECP_3142 Escherichia coli 536 glutamate-ammonia-ligase adenylyltransferase YP_671026.1 3308587 R 362663 CDS YP_671027.1 110643297 4188560 complement(3310716..3311426) 1 NC_008253.1 glutamate-ammonia-ligase adenylyltransferase 3311426 4188560 ECP_3143 Escherichia coli 536 glutamate-ammonia-ligase adenylyltransferase YP_671027.1 3310716 R 362663 CDS YP_671028.1 110643298 4188561 complement(3311449..3312750) 1 NC_008253.1 hypothetical protein 3312750 4188561 ECP_3144 Escherichia coli 536 hypothetical protein YP_671028.1 3311449 R 362663 CDS YP_671029.1 110643299 4188562 3312992..3313612 1 NC_008253.1 signal transduction protein 3313612 4188562 ECP_3145 Escherichia coli 536 signal transduction protein YP_671029.1 3312992 D 362663 CDS YP_671030.1 110643300 4188563 3313676..3314914 1 NC_008253.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3314914 cca 4188563 cca Escherichia coli 536 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_671030.1 3313676 D 362663 CDS YP_671031.1 110643301 4188564 complement(3314995..3315816) 1 NC_008253.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3315816 4188564 ECP_3147 Escherichia coli 536 undecaprenyl pyrophosphate phosphatase YP_671031.1 3314995 R 362663 CDS YP_671032.1 110643302 4188565 complement(3315907..3316275) 1 NC_008253.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3316275 folB 4188565 folB Escherichia coli 536 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_671032.1 3315907 R 362663 CDS YP_671033.1 110643303 4188566 3316380..3316997 1 NC_008253.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3316997 4188566 ECP_3149 Escherichia coli 536 glycerol-3-phosphate acyltransferase PlsY YP_671033.1 3316380 D 362663 CDS YP_671034.1 110643304 4188567 complement(3317010..3317942) 1 NC_008253.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3317942 4188567 ECP_3150 Escherichia coli 536 transcriptional activator TtdR YP_671034.1 3317010 R 362663 CDS YP_671035.1 110643305 4188568 3318149..3319060 1 NC_008253.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3319060 4188568 ECP_3151 Escherichia coli 536 tartrate dehydratase subunit alpha YP_671035.1 3318149 D 362663 CDS YP_671036.1 110643306 4188641 3319057..3319662 1 NC_008253.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3319662 4188641 ECP_3152 Escherichia coli 536 L(+)-tartrate dehydratase subunit beta YP_671036.1 3319057 D 362663 CDS YP_671037.1 110643307 4188642 3319710..3321173 1 NC_008253.1 tartrate carrier 3321173 4188642 ECP_3153 Escherichia coli 536 tartrate carrier YP_671037.1 3319710 D 362663 CDS YP_671038.1 110643308 4188643 complement(3321216..3322229) 1 NC_008253.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3322229 4188643 ECP_3154 Escherichia coli 536 DNA-binding/iron metalloprotein/AP endonuclease YP_671038.1 3321216 R 362663 CDS YP_671039.1 110643309 4188644 3322467..3322682 1 NC_008253.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3322682 rpsU 4188644 rpsU Escherichia coli 536 30S ribosomal protein S21 YP_671039.1 3322467 D 362663 CDS YP_671040.1 110643310 4188645 3322793..3324538 1 NC_008253.1 synthesizes RNA primers at the replication forks; DNA primase 3324538 dnaG 4188645 dnaG Escherichia coli 536 DNA primase YP_671040.1 3322793 D 362663 CDS YP_671041.1 110643311 4188646 3324733..3326574 1 NC_008253.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3326574 4188646 ECP_3157 Escherichia coli 536 RNA polymerase sigma factor RpoD YP_671041.1 3324733 D 362663 CDS YP_671042.1 110643312 4188647 complement(3326653..3327159) 1 NC_008253.1 G/U mismatch-specific DNA glycosylase 3327159 4188647 ECP_3158 Escherichia coli 536 G/U mismatch-specific DNA glycosylase YP_671042.1 3326653 R 362663 CDS YP_671043.1 110643313 4188649 complement(3327413..3328177) 1 NC_008253.1 hypothetical protein 3328177 4188649 ECP_3160 Escherichia coli 536 hypothetical protein YP_671043.1 3327413 R 362663 CDS YP_671044.1 110643314 4188650 3328465..3329088 1 NC_008253.1 hypothetical protein 3329088 4188650 ECP_3161 Escherichia coli 536 hypothetical protein YP_671044.1 3328465 D 362663 CDS YP_671045.1 110643315 4188651 complement(3329117..3330637) 1 NC_008253.1 aerotaxis receptor 3330637 4188651 ECP_3162 Escherichia coli 536 aerotaxis receptor YP_671045.1 3329117 R 362663 CDS YP_671046.1 110643316 4188652 3330944..3332434 1 NC_008253.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3332434 4188652 ECP_3163 Escherichia coli 536 putrescine--2-oxoglutarate aminotransferase YP_671046.1 3330944 D 362663 CDS YP_671047.1 110643317 4188653 complement(3332476..3332808) 1 NC_008253.1 hypothetical protein 3332808 4188653 ECP_3164 Escherichia coli 536 hypothetical protein YP_671047.1 3332476 R 362663 CDS YP_671048.1 110643318 4188654 3332915..3333097 1 NC_008253.1 hypothetical protein 3333097 4188654 ECP_3165 Escherichia coli 536 hypothetical protein YP_671048.1 3332915 D 362663 CDS YP_671049.1 110643319 4188655 3333027..3334010 1 NC_008253.1 DNA-binding transcriptional repressor EbgR 3334010 4188655 ECP_3166 Escherichia coli 536 DNA-binding transcriptional repressor EbgR YP_671049.1 3333027 D 362663 CDS YP_671050.1 110643320 4188656 3334194..3337286 1 NC_008253.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3337286 ebgA 4188656 ebgA Escherichia coli 536 cryptic beta-D-galactosidase subunit alpha YP_671050.1 3334194 D 362663 CDS YP_671051.1 110643321 4188657 3337283..3337732 1 NC_008253.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3337732 ebgC 4188657 ebgC Escherichia coli 536 cryptic beta-D-galactosidase subunit beta YP_671051.1 3337283 D 362663 CDS YP_671052.1 110643322 4188658 3337795..3339228 1 NC_008253.1 transporter YgjI 3339228 4188658 ECP_3169 Escherichia coli 536 transporter YgjI YP_671052.1 3337795 D 362663 CDS YP_671053.1 110643323 4188659 3339362..3340432 1 NC_008253.1 hypothetical protein 3340432 4188659 ECP_3170 Escherichia coli 536 hypothetical protein YP_671053.1 3339362 D 362663 CDS YP_671054.1 110643324 4188452 3340449..3342800 1 NC_008253.1 glycosyl hydrolase 3342800 4188452 ECP_3171 Escherichia coli 536 glycosyl hydrolase YP_671054.1 3340449 D 362663 CDS YP_671055.1 110643325 4188453 3342971..3344989 1 NC_008253.1 2,4-dienoyl-CoA reductase 3344989 4188453 ECP_3172 Escherichia coli 536 2,4-dienoyl-CoA reductase YP_671055.1 3342971 D 362663 CDS YP_671056.1 110643326 4188454 complement(3345082..3345498) 1 NC_008253.1 hypothetical protein 3345498 4188454 ECP_3173 Escherichia coli 536 hypothetical protein YP_671056.1 3345082 R 362663 CDS YP_671057.1 110643327 4188455 complement(3345495..3345665) 1 NC_008253.1 hypothetical protein 3345665 4188455 ECP_3174 Escherichia coli 536 hypothetical protein YP_671057.1 3345495 R 362663 CDS YP_671058.1 110643328 4188456 complement(3345769..3346905) 1 NC_008253.1 ribosomal RNA small subunit methyltransferase D 3346905 4188456 ECP_3175 Escherichia coli 536 ribosomal RNA small subunit methyltransferase D YP_671058.1 3345769 R 362663 CDS YP_671059.1 110643329 4188457 3346990..3347493 1 NC_008253.1 hypothetical protein 3347493 4188457 ECP_3176 Escherichia coli 536 hypothetical protein YP_671059.1 3346990 D 362663 CDS YP_671060.1 110643330 4188458 3347570..3348253 1 NC_008253.1 hypothetical protein 3348253 4188458 ECP_3177 Escherichia coli 536 hypothetical protein YP_671060.1 3347570 D 362663 CDS YP_671061.1 110643331 4188459 3348332..3349318 1 NC_008253.1 oxidoreductase YgjR 3349318 4188459 ECP_3178 Escherichia coli 536 oxidoreductase YgjR YP_671061.1 3348332 D 362663 CDS YP_671062.1 110643332 4188460 3349601..3350566 1 NC_008253.1 hypothetical protein 3350566 4188460 ECP_3179 Escherichia coli 536 hypothetical protein YP_671062.1 3349601 D 362663 CDS YP_671063.1 110643333 4188461 3350890..3352134 1 NC_008253.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3352134 4188461 ECP_3180 Escherichia coli 536 serine/threonine transporter SstT YP_671063.1 3350890 D 362663 CDS YP_671064.1 110643334 4188462 complement(3352138..3352689) 1 NC_008253.1 hypothetical protein 3352689 4188462 ECP_3181 Escherichia coli 536 hypothetical protein YP_671064.1 3352138 R 362663 CDS YP_671065.1 110643335 4188463 complement(3352772..3354259) 1 NC_008253.1 altronate hydrolase 3354259 4188463 ECP_3182 Escherichia coli 536 altronate hydrolase YP_671065.1 3352772 R 362663 CDS YP_671066.1 110643336 4188464 complement(3354274..3355686) 1 NC_008253.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3355686 4188464 ECP_3183 Escherichia coli 536 glucuronate isomerase YP_671066.1 3354274 R 362663 CDS YP_671067.1 110643337 4188465 3356169..3357467 1 NC_008253.1 hexuronate transporter 3357467 4188465 ECP_3184 Escherichia coli 536 hexuronate transporter YP_671067.1 3356169 D 362663 CDS YP_671068.1 110643338 4188466 complement(3357543..3358625) 1 NC_008253.1 minor pilin protein 3358625 4188466 ECP_3185 Escherichia coli 536 minor pilin protein YP_671068.1 3357543 R 362663 CDS YP_671069.1 110643339 4188467 complement(3358622..3361006) 1 NC_008253.1 usher protein 3361006 4188467 ECP_3186 Escherichia coli 536 usher protein YP_671069.1 3358622 R 362663 CDS YP_671070.1 110643340 4188468 complement(3360966..3361325) 1 NC_008253.1 hypothetical protein 3361325 4188468 ECP_3187 Escherichia coli 536 hypothetical protein YP_671070.1 3360966 R 362663 CDS YP_671071.1 110643341 4188469 complement(3361398..3361898) 1 NC_008253.1 CS1 type fimbrial major subunit 3361898 4188469 ECP_3188 Escherichia coli 536 CS1 type fimbrial major subunit YP_671071.1 3361398 R 362663 CDS YP_671072.1 110643342 4188470 complement(3361928..3362644) 1 NC_008253.1 fimbrial protein 3362644 4188470 ECP_3189 Escherichia coli 536 fimbrial protein YP_671072.1 3361928 R 362663 CDS YP_671073.1 110643343 4188491 3362935..3363711 1 NC_008253.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3363711 4188491 ECP_3190 Escherichia coli 536 DNA-binding transcriptional repressor ExuR YP_671073.1 3362935 D 362663 CDS YP_671074.1 110643344 4188492 3364056..3364718 1 NC_008253.1 DedA family membrane protein 3364718 4188492 ECP_3191 Escherichia coli 536 DedA family membrane protein YP_671074.1 3364056 D 362663 CDS YP_671075.1 110643345 4188493 3364722..3365105 1 NC_008253.1 hypothetical protein 3365105 4188493 ECP_3192 Escherichia coli 536 hypothetical protein YP_671075.1 3364722 D 362663 CDS YP_671076.2 229560211 4188494 3365252..3365620 1 NC_008253.1 hypothetical protein 3365620 4188494 ECP_3193 Escherichia coli 536 hypothetical protein YP_671076.2 3365252 D 362663 CDS YP_671077.1 110643347 4188495 3365658..3365963 1 NC_008253.1 hypothetical protein 3365963 4188495 ECP_3194 Escherichia coli 536 hypothetical protein YP_671077.1 3365658 D 362663 CDS YP_671078.1 110643348 4188496 3365966..3366370 1 NC_008253.1 hypothetical protein 3366370 4188496 ECP_3195 Escherichia coli 536 hypothetical protein YP_671078.1 3365966 D 362663 CDS YP_671079.1 110643349 4188497 3366360..3366659 1 NC_008253.1 hypothetical protein 3366659 4188497 ECP_3196 Escherichia coli 536 hypothetical protein YP_671079.1 3366360 D 362663 CDS YP_671080.1 110643350 4188498 3366846..3367238 1 NC_008253.1 hypothetical protein 3367238 4188498 ECP_3197 Escherichia coli 536 hypothetical protein YP_671080.1 3366846 D 362663 CDS YP_671081.1 110643351 4188499 3367308..3368294 1 NC_008253.1 glutathione S-transferase 3368294 4188499 ECP_3198 Escherichia coli 536 glutathione S-transferase YP_671081.1 3367308 D 362663 CDS YP_671082.1 110643352 4188500 3368577..3368945 1 NC_008253.1 hypothetical protein 3368945 4188500 ECP_3199 Escherichia coli 536 hypothetical protein YP_671082.1 3368577 D 362663 CDS YP_671083.1 110643353 4188501 complement(3368979..3369875) 1 NC_008253.1 LysR family transcriptional regulator 3369875 4188501 ECP_3200 Escherichia coli 536 LysR family transcriptional regulator YP_671083.1 3368979 R 362663 CDS YP_671084.1 110643354 4188502 3369980..3370681 1 NC_008253.1 hypothetical protein 3370681 4188502 ECP_3201 Escherichia coli 536 hypothetical protein YP_671084.1 3369980 D 362663 CDS YP_671085.1 110643355 4188503 3370704..3370868 1 NC_008253.1 hypothetical protein 3370868 4188503 ECP_3202 Escherichia coli 536 hypothetical protein YP_671085.1 3370704 D 362663 CDS YP_671086.1 110643356 4188504 complement(3370929..3372239) 1 NC_008253.1 hypothetical protein 3372239 4188504 ECP_3203 Escherichia coli 536 hypothetical protein YP_671086.1 3370929 R 362663 CDS YP_671087.1 110643357 4188505 complement(3372267..3373598) 1 NC_008253.1 hypothetical protein 3373598 4188505 ECP_3204 Escherichia coli 536 hypothetical protein YP_671087.1 3372267 R 362663 CDS YP_671088.1 110643358 4188506 complement(3373876..3375240) 1 NC_008253.1 L-serine dehydratase tdcG 3375240 4188506 ECP_3205 Escherichia coli 536 L-serine dehydratase tdcG YP_671088.1 3373876 R 362663 CDS YP_671089.1 110643359 4188507 complement(3375312..3375701) 1 NC_008253.1 hypothetical protein 3375701 4188507 ECP_3206 Escherichia coli 536 hypothetical protein YP_671089.1 3375312 R 362663 CDS YP_671090.1 110643360 4188508 complement(3375715..3378009) 1 NC_008253.1 keto-acid formate acetyltransferase 3378009 4188508 ECP_3207 Escherichia coli 536 keto-acid formate acetyltransferase YP_671090.1 3375715 R 362663 CDS YP_671091.2 162138275 4188509 complement(3378043..3379263) 1 NC_008253.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3379263 4188509 ECP_3208 Escherichia coli 536 propionate/acetate kinase YP_671091.2 3378043 R 362663 CDS YP_671092.1 110643362 4188510 complement(3379277..3380608) 1 NC_008253.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3380608 4188510 ECP_3209 Escherichia coli 536 threonine/serine transporter TdcC YP_671092.1 3379277 R 362663 CDS YP_671093.1 110643363 4188531 complement(3380630..3381619) 1 NC_008253.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3381619 4188531 ECP_3210 Escherichia coli 536 threonine dehydratase YP_671093.1 3380630 R 362663 CDS YP_671094.1 110643364 4188532 complement(3381718..3382656) 1 NC_008253.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3382656 4188532 ECP_3211 Escherichia coli 536 DNA-binding transcriptional activator TdcA YP_671094.1 3381718 R 362663 CDS YP_671095.1 110643365 4188533 3382845..3383189 1 NC_008253.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3383189 4188533 ECP_3212 Escherichia coli 536 DNA-binding transcriptional activator TdcR YP_671095.1 3382845 D 362663 CDS YP_671096.1 110643366 4188534 3383778..3384227 1 NC_008253.1 hypothetical protein 3384227 4188534 ECP_3213 Escherichia coli 536 hypothetical protein YP_671096.1 3383778 D 362663 CDS YP_671097.1 110643367 4188535 complement(3384155..3385381) 1 NC_008253.1 glycerate kinase 3385381 4188535 ECP_3214 Escherichia coli 536 glycerate kinase YP_671097.1 3384155 R 362663 CDS YP_671098.1 110643368 4188536 complement(3385397..3386296) 1 NC_008253.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3386296 garR 4188536 garR Escherichia coli 536 tartronate semialdehyde reductase YP_671098.1 3385397 R 362663 CDS YP_671099.1 110643369 4188537 complement(3386317..3387087) 1 NC_008253.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3387087 4188537 ECP_3216 Escherichia coli 536 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_671099.1 3386317 R 362663 CDS YP_671100.1 110643370 4188538 complement(3387103..3388437) 1 NC_008253.1 galactarate transporter 3388437 4188538 ECP_3217 Escherichia coli 536 galactarate transporter YP_671100.1 3387103 R 362663 CDS YP_671101.1 110643371 4188539 3388812..3390383 1 NC_008253.1 D-galactarate dehydratase 3390383 4188539 ECP_3218 Escherichia coli 536 D-galactarate dehydratase YP_671101.1 3388812 D 362663 CDS YP_671102.1 110643372 4188540 3390532..3390867 1 NC_008253.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3390867 4188540 ECP_3219 Escherichia coli 536 regulator PrlF YP_671102.1 3390532 D 362663 CDS YP_671103.1 110643373 4188541 3390867..3391331 1 NC_008253.1 hypothetical protein 3391331 4188541 ECP_3220 Escherichia coli 536 hypothetical protein YP_671103.1 3390867 D 362663 CDS YP_671104.1 110643374 4188542 complement(3391386..3392195) 1 NC_008253.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3392195 4188542 ECP_3221 Escherichia coli 536 DNA-binding transcriptional regulator AgaR YP_671104.1 3391386 R 362663 CDS YP_671105.1 110643375 4188543 3392444..3393724 1 NC_008253.1 tagatose 6-phosphate kinase agaZ 3393724 4188543 ECP_3222 Escherichia coli 536 tagatose 6-phosphate kinase agaZ YP_671105.1 3392444 D 362663 CDS YP_671106.1 110643376 4188544 3393747..3394220 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIB 3394220 4188544 ECP_3223 Escherichia coli 536 N-acetylgalactosamine-specific PTS system transporter subunit IIB YP_671106.1 3393747 D 362663 CDS YP_671107.1 110643377 4188545 3394231..3395010 1 NC_008253.1 phosphotransferase system enzyme subunit (AgaW) 3395010 4188545 ECP_3224 Escherichia coli 536 phosphotransferase system enzyme subunit (AgaW) YP_671107.1 3394231 D 362663 CDS YP_671108.1 110643378 4188546 3395000..3395896 1 NC_008253.1 PTS system N-acetylgalactosamine-specific transporter subunit IID 3395896 4188546 ECP_3225 Escherichia coli 536 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_671108.1 3395000 D 362663 CDS YP_671109.1 110643379 4188547 3395943..3396332 1 NC_008253.1 phosphotransferase system enzyme subunit (AgaF) 3396332 4188547 ECP_3226 Escherichia coli 536 phosphotransferase system enzyme subunit (AgaF) YP_671109.1 3395943 D 362663 CDS YP_671110.1 110643380 4188548 3396329..3397462 1 NC_008253.1 N-acetylgalctosamine-6-phosphate deacetylase 3397462 4188548 ECP_3227 Escherichia coli 536 N-acetylgalctosamine-6-phosphate deacetylase YP_671110.1 3396329 D 362663 CDS YP_671111.1 110643381 4188549 3397812..3398966 1 NC_008253.1 tagatose-6-phosphate ketose/aldose isomerase 3398966 4188549 ECP_3228 Escherichia coli 536 tagatose-6-phosphate ketose/aldose isomerase YP_671111.1 3397812 D 362663 CDS YP_671112.1 110643382 4188585 3398979..3399839 1 NC_008253.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3399839 kbaY 4188585 kbaY Escherichia coli 536 tagatose-bisphosphate aldolase YP_671112.1 3398979 D 362663 CDS YP_671113.1 110643383 4188586 3400006..3400482 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIB 3400482 4188586 ECP_3230 Escherichia coli 536 N-acetylgalactosamine-specific PTS system transporter subunit IIB YP_671113.1 3400006 D 362663 CDS YP_671114.1 110643384 4188587 3400521..3401324 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IIC 3401324 4188587 ECP_3231 Escherichia coli 536 N-acetylgalactosamine-specific PTS system transporter subunit IIC YP_671114.1 3400521 D 362663 CDS YP_671115.1 110643385 4188588 3401314..3402105 1 NC_008253.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; N-acetylgalactosamine-specific PTS system transporter subunit IID 3402105 4188588 ECP_3232 Escherichia coli 536 N-acetylgalactosamine-specific PTS system transporter subunit IID YP_671115.1 3401314 D 362663 CDS YP_671116.1 110643386 4188589 3402106..3402873 1 NC_008253.1 galactosamine-6-phosphate isomerase 3402873 4188589 ECP_3233 Escherichia coli 536 galactosamine-6-phosphate isomerase YP_671116.1 3402106 D 362663 CDS YP_671117.1 110643387 4188590 complement(3402923..3403786) 1 NC_008253.1 tetrapyrrole methylase 3403786 4188590 ECP_3234 Escherichia coli 536 tetrapyrrole methylase YP_671117.1 3402923 R 362663 CDS YP_671118.1 110643388 4188591 3403851..3405887 1 NC_008253.1 hypothetical protein 3405887 4188591 ECP_3235 Escherichia coli 536 hypothetical protein YP_671118.1 3403851 D 362663 CDS YP_671119.1 110643389 4188592 3405845..3406240 1 NC_008253.1 hypothetical protein 3406240 4188592 ECP_3236 Escherichia coli 536 hypothetical protein YP_671119.1 3405845 D 362663 CDS YP_671120.1 110643390 4188593 3406260..3406850 1 NC_008253.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3406850 4188593 ECP_3237 Escherichia coli 536 DnaA initiator-associating protein DiaA YP_671120.1 3406260 D 362663 CDS YP_671121.1 110643391 4188594 3406860..3407435 1 NC_008253.1 hypothetical protein 3407435 4188594 ECP_3238 Escherichia coli 536 hypothetical protein YP_671121.1 3406860 D 362663 CDS YP_671122.1 110643392 4188595 complement(3407548..3408588) 1 NC_008253.1 hypothetical protein 3408588 4188595 ECP_3239 Escherichia coli 536 hypothetical protein YP_671122.1 3407548 R 362663 CDS YP_671123.1 110643393 4188596 complement(3408661..3409296) 1 NC_008253.1 hypothetical protein 3409296 4188596 ECP_3240 Escherichia coli 536 hypothetical protein YP_671123.1 3408661 R 362663 CDS YP_671124.1 110643394 4188597 3409424..3409942 1 NC_008253.1 hypothetical protein 3409942 4188597 ECP_3241 Escherichia coli 536 hypothetical protein YP_671124.1 3409424 D 362663 CDS YP_671125.1 110643395 4188598 complement(3409922..3410365) 1 NC_008253.1 hypothetical protein 3410365 4188598 ECP_3242 Escherichia coli 536 hypothetical protein YP_671125.1 3409922 R 362663 CDS YP_671126.1 110643396 4188599 3410416..3410718 1 NC_008253.1 GIY-YIG nuclease superfamily protein 3410718 4188599 ECP_3243 Escherichia coli 536 GIY-YIG nuclease superfamily protein YP_671126.1 3410416 D 362663 CDS YP_671127.1 110643397 4188600 complement(3410705..3411208) 1 NC_008253.1 acetyltransferase YhbS 3411208 4188600 ECP_3244 Escherichia coli 536 acetyltransferase YhbS YP_671127.1 3410705 R 362663 CDS YP_671128.1 110643398 4188601 complement(3411202..3411750) 1 NC_008253.1 hypothetical protein 3411750 4188601 ECP_3245 Escherichia coli 536 hypothetical protein YP_671128.1 3411202 R 362663 CDS YP_671129.1 110643399 4188602 3411935..3412930 1 NC_008253.1 protease YhbU 3412930 4188602 ECP_3246 Escherichia coli 536 protease YhbU YP_671129.1 3411935 D 362663 CDS YP_671130.1 110643400 4188603 3412939..3413817 1 NC_008253.1 peptidase YhbV 3413817 4188603 ECP_3247 Escherichia coli 536 peptidase YhbV YP_671130.1 3412939 D 362663 CDS YP_671131.1 110643401 4188604 3413898..3414905 1 NC_008253.1 hypothetical protein 3414905 4188604 ECP_3248 Escherichia coli 536 hypothetical protein YP_671131.1 3413898 D 362663 CDS YP_671132.1 110643402 4188660 complement(3415023..3416267) 1 NC_008253.1 tryptophan transporter of high affinity; tryptophan permease 3416267 4188660 ECP_3249 Escherichia coli 536 tryptophan permease YP_671132.1 3415023 R 362663 CDS YP_671133.1 110643403 4188661 complement(3416421..3418310) 1 NC_008253.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3418310 4188661 ECP_3250 Escherichia coli 536 ATP-dependent RNA helicase DeaD YP_671133.1 3416421 R 362663 CDS YP_671134.1 110643404 4188662 complement(3418490..3419374) 1 NC_008253.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3419374 4188662 ECP_3251 Escherichia coli 536 lipoprotein NlpI YP_671134.1 3418490 R 362663 CDS YP_671135.1 110643405 4188663 complement(3419483..3421687) 1 NC_008253.1 polynucleotide phosphorylase 3421687 4188663 ECP_3252 Escherichia coli 536 polynucleotide phosphorylase YP_671135.1 3419483 R 362663 CDS YP_671136.1 110643406 4188664 complement(3421865..3422134) 1 NC_008253.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3422134 rpsO 4188664 rpsO Escherichia coli 536 30S ribosomal protein S15 YP_671136.1 3421865 R 362663 CDS YP_671137.1 110643407 4188665 complement(3422283..3423227) 1 NC_008253.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3423227 truB 4188665 truB Escherichia coli 536 tRNA pseudouridine synthase B YP_671137.1 3422283 R 362663 CDS YP_671138.1 110643408 4188666 complement(3423227..3423628) 1 NC_008253.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3423628 rbfA 4188666 rbfA Escherichia coli 536 ribosome-binding factor A YP_671138.1 3423227 R 362663 CDS YP_671139.1 110643409 4188667 complement(3423792..3426464) 1 NC_008253.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3426464 infB 4188667 infB Escherichia coli 536 translation initiation factor IF-2 YP_671139.1 3423792 R 362663 CDS YP_671140.1 110643410 4188668 complement(3426489..3427976) 1 NC_008253.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3427976 nusA 4188668 nusA Escherichia coli 536 transcription elongation factor NusA YP_671140.1 3426489 R 362663 CDS YP_671141.1 110643411 4188669 complement(3428004..3428456) 1 NC_008253.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3428456 4188669 ECP_3258 Escherichia coli 536 hypothetical protein YP_671141.1 3428004 R 362663 CDS YP_671142.1 110643412 4188670 3429087..3430430 1 NC_008253.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3430430 4188670 ECP_3259 Escherichia coli 536 argininosuccinate synthase YP_671142.1 3429087 D 362663 CDS YP_671143.1 110643413 4188671 complement(3430438..3431169) 1 NC_008253.1 hypothetical protein 3431169 4188671 ECP_3260 Escherichia coli 536 hypothetical protein YP_671143.1 3430438 R 362663 CDS YP_671144.1 110643414 4188672 complement(3431268..3431954) 1 NC_008253.1 hypothetical protein 3431954 4188672 ECP_3261 Escherichia coli 536 hypothetical protein YP_671144.1 3431268 R 362663 CDS YP_671145.1 110643415 4188673 complement(3432620..3432952) 1 NC_008253.1 preprotein translocase subunit SecG 3432952 secG 4188673 secG Escherichia coli 536 preprotein translocase subunit SecG YP_671145.1 3432620 R 362663 CDS YP_671146.1 110643416 4188674 complement(3433180..3434517) 1 NC_008253.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3434517 glmM 4188674 glmM Escherichia coli 536 phosphoglucosamine mutase YP_671146.1 3433180 R 362663 CDS YP_671147.1 110643417 4188675 complement(3434510..3435358) 1 NC_008253.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3435358 folP 4188675 folP Escherichia coli 536 dihydropteroate synthase YP_671147.1 3434510 R 362663 CDS YP_671148.1 110643418 4188676 complement(3435448..3437382) 1 NC_008253.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3437382 hflB 4188676 hflB Escherichia coli 536 ATP-dependent metalloprotease YP_671148.1 3435448 R 362663 CDS YP_671149.1 110643419 4188677 complement(3437482..3438111) 1 NC_008253.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 3438111 rrmJ 4188677 rrmJ Escherichia coli 536 23S rRNA methyltransferase YP_671149.1 3437482 R 362663 CDS YP_671150.1 110643420 4188678 3438237..3438530 1 NC_008253.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3438530 4188678 ECP_3267 Escherichia coli 536 RNA-binding protein YhbY YP_671150.1 3438237 D 362663 CDS YP_671151.1 110643421 4187661 complement(3438686..3439162) 1 NC_008253.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3439162 greA 4187661 greA Escherichia coli 536 transcription elongation factor GreA YP_671151.1 3438686 R 362663 CDS YP_671152.1 110643422 4187662 3439410..3440843 1 NC_008253.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3440843 4187662 ECP_3269 Escherichia coli 536 D-alanyl-D-alanine carboxypeptidase YP_671152.1 3439410 D 362663 CDS YP_671153.1 110643423 4187663 complement(3440884..3442056) 1 NC_008253.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3442056 obgE 4187663 obgE Escherichia coli 536 GTPase ObgE YP_671153.1 3440884 R 362663 CDS YP_671154.1 110643424 4187664 complement(3442072..3443037) 1 NC_008253.1 transporter 3443037 4187664 ECP_3271 Escherichia coli 536 transporter YP_671154.1 3442072 R 362663 CDS YP_671155.1 110643425 4187665 complement(3443165..3443422) 1 NC_008253.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3443422 rpmA 4187665 rpmA Escherichia coli 536 50S ribosomal protein L27 YP_671155.1 3443165 R 362663 CDS YP_671156.1 110643426 4187666 complement(3443443..3443754) 1 NC_008253.1 50S ribosomal protein L21 3443754 rplU 4187666 rplU Escherichia coli 536 50S ribosomal protein L21 YP_671156.1 3443443 R 362663 CDS YP_671157.1 110643427 4187667 3444013..3444984 1 NC_008253.1 octaprenyl diphosphate synthase 3444984 4187667 ECP_3274 Escherichia coli 536 octaprenyl diphosphate synthase YP_671157.1 3444013 D 362663 CDS YP_671158.1 110643428 4187668 3445217..3445495 1 NC_008253.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3445495 4187668 ECP_3275 Escherichia coli 536 DNA-binding transcriptional regulator Nlp YP_671158.1 3445217 D 362663 CDS YP_671159.1 110643429 4187669 complement(3445543..3446802) 1 NC_008253.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3446802 4187669 ECP_3276 Escherichia coli 536 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_671159.1 3445543 R 362663 CDS YP_671160.1 110643430 4187670 complement(3446857..3447126) 1 NC_008253.1 BolA family transcriptional regulator 3447126 4187670 ECP_3277 Escherichia coli 536 BolA family transcriptional regulator YP_671160.1 3446857 R 362663 CDS YP_671161.1 110643431 4187671 complement(3447271..3447564) 1 NC_008253.1 hypothetical protein 3447564 4187671 ECP_3278 Escherichia coli 536 hypothetical protein YP_671161.1 3447271 R 362663 CDS YP_671162.1 110643432 4187672 complement(3447564..3448199) 1 NC_008253.1 hypothetical protein 3448199 4187672 ECP_3279 Escherichia coli 536 hypothetical protein YP_671162.1 3447564 R 362663 CDS YP_671163.1 110643433 4187673 complement(3448218..3448769) 1 NC_008253.1 hypothetical protein 3448769 4187673 ECP_3280 Escherichia coli 536 hypothetical protein YP_671163.1 3448218 R 362663 CDS YP_671164.1 110643434 4187674 complement(3448774..3449556) 1 NC_008253.1 hypothetical protein 3449556 4187674 ECP_3281 Escherichia coli 536 hypothetical protein YP_671164.1 3448774 R 362663 CDS YP_671165.1 110643435 4187675 complement(3449564..3450373) 1 NC_008253.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein 3450373 4187675 ECP_3282 Escherichia coli 536 ABC transporter ATP-binding protein YP_671165.1 3449564 R 362663 CDS YP_671166.1 110643436 4187676 3450583..3451269 1 NC_008253.1 sodium/calcium exchanger protein 3451269 4187676 ECP_3283 Escherichia coli 536 sodium/calcium exchanger protein YP_671166.1 3450583 D 362663 CDS YP_671167.1 110643437 4187677 3451344..3451559 1 NC_008253.1 hypothetical protein 3451559 4187677 ECP_3284 Escherichia coli 536 hypothetical protein YP_671167.1 3451344 D 362663 CDS YP_671168.1 110643438 4187678 3451573..3452559 1 NC_008253.1 D-arabinose 5-phosphate isomerase 3452559 4187678 ECP_3285 Escherichia coli 536 D-arabinose 5-phosphate isomerase YP_671168.1 3451573 D 362663 CDS YP_671169.1 110643439 4187679 3452580..3453146 1 NC_008253.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3453146 4187679 ECP_3286 Escherichia coli 536 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_671169.1 3452580 D 362663 CDS YP_671170.1 110643440 4187680 3453143..3453718 1 NC_008253.1 hypothetical protein 3453718 4187680 ECP_3287 Escherichia coli 536 hypothetical protein YP_671170.1 3453143 D 362663 CDS YP_671171.1 110643441 4189548 3453687..3454244 1 NC_008253.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3454244 4189548 ECP_3288 Escherichia coli 536 lipopolysaccharide transport periplasmic protein LptA YP_671171.1 3453687 D 362663 CDS YP_671172.1 110643442 4189549 3454251..3454976 1 NC_008253.1 ABC transporter ATP-binding protein 3454976 4189549 ECP_3289 Escherichia coli 536 ABC transporter ATP-binding protein YP_671172.1 3454251 D 362663 CDS YP_671173.1 110643443 4189550 3455024..3456457 1 NC_008253.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3456457 4189550 ECP_3290 Escherichia coli 536 RNA polymerase factor sigma-54 YP_671173.1 3455024 D 362663 CDS YP_671174.1 110643444 4189551 3456480..3456767 1 NC_008253.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3456767 4189551 ECP_3291 Escherichia coli 536 sigma(54) modulation protein YP_671174.1 3456480 D 362663 CDS YP_671175.1 110643445 4189552 3456885..3457376 1 NC_008253.1 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN 3457376 4189552 ECP_3292 Escherichia coli 536 PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_671175.1 3456885 D 362663 CDS YP_671176.1 110643446 4189553 3457422..3458276 1 NC_008253.1 hypothetical protein 3458276 4189553 ECP_3293 Escherichia coli 536 hypothetical protein YP_671176.1 3457422 D 362663 CDS YP_671177.1 110643447 4189554 3458273..3458545 1 NC_008253.1 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3458545 4189554 ECP_3294 Escherichia coli 536 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_671177.1 3458273 D 362663 CDS YP_671178.1 110643448 4189555 3458759..3459391 1 NC_008253.1 hypothetical protein 3459391 4189555 ECP_3295 Escherichia coli 536 hypothetical protein YP_671178.1 3458759 D 362663 CDS YP_671179.1 110643449 4189556 complement(3459388..3460116) 1 NC_008253.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3460116 mtgA 4189556 mtgA Escherichia coli 536 monofunctional biosynthetic peptidoglycan transglycosylase YP_671179.1 3459388 R 362663 CDS YP_671180.1 110643450 4189557 complement(3460113..3460766) 1 NC_008253.1 isoprenoid biosynthesis protein with amidotransferase-like domain 3460766 4189557 ECP_3297 Escherichia coli 536 isoprenoid biosynthesis protein with amidotransferase-like domain YP_671180.1 3460113 R 362663 CDS YP_671181.1 110643451 4189558 complement(3460996..3463332) 1 NC_008253.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3463332 4189558 ECP_3298 Escherichia coli 536 aerobic respiration control sensor protein ArcB YP_671181.1 3460996 R 362663 CDS YP_671182.1 110643452 4189559 complement(3463428..3464357) 1 NC_008253.1 hypothetical protein 3464357 4189559 ECP_3299 Escherichia coli 536 hypothetical protein YP_671182.1 3463428 R 362663 CDS YP_671183.1 110643453 4189562 3469506..3470924 1 NC_008253.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3470924 gltD 4189562 gltD Escherichia coli 536 glutamate synthase subunit beta YP_671183.1 3469506 D 362663 CDS YP_671184.1 110643454 4189563 3471108..3472235 1 NC_008253.1 hypothetical protein 3472235 4189563 ECP_3303 Escherichia coli 536 hypothetical protein YP_671184.1 3471108 D 362663 CDS YP_671185.1 110643455 4189564 complement(3472295..3472759) 1 NC_008253.1 hypothetical protein 3472759 4189564 ECP_3304 Escherichia coli 536 hypothetical protein YP_671185.1 3472295 R 362663 CDS YP_671186.1 110643456 4188825 complement(3472756..3473631) 1 NC_008253.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3473631 4188825 ECP_3305 Escherichia coli 536 N-acetylmannosamine kinase YP_671186.1 3472756 R 362663 CDS YP_671187.1 110643457 4188826 complement(3473628..3474317) 1 NC_008253.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3474317 4188826 ECP_3306 Escherichia coli 536 N-acetylmannosamine-6-phosphate 2-epimerase YP_671187.1 3473628 R 362663 CDS YP_671188.1 110643458 4188827 complement(3474365..3475855) 1 NC_008253.1 sialic acid transporter 3475855 4188827 ECP_3307 Escherichia coli 536 sialic acid transporter YP_671188.1 3474365 R 362663 CDS YP_671189.1 110643459 4188828 complement(3475964..3476857) 1 NC_008253.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3476857 4188828 ECP_3308 Escherichia coli 536 N-acetylneuraminate lyase YP_671189.1 3475964 R 362663 CDS YP_671190.1 110643460 4188829 complement(3476979..3477770) 1 NC_008253.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3477770 4188829 ECP_3309 Escherichia coli 536 transcriptional regulator NanR YP_671190.1 3476979 R 362663 CDS YP_671191.1 110643461 4188830 complement(3477878..3478375) 1 NC_008253.1 ClpXP protease specificity-enhancing factor 3478375 4188830 ECP_3310 Escherichia coli 536 ClpXP protease specificity-enhancing factor YP_671191.1 3477878 R 362663 CDS YP_671192.1 110643462 4188831 complement(3478381..3479019) 1 NC_008253.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3479019 sspA 4188831 sspA Escherichia coli 536 stringent starvation protein A YP_671192.1 3478381 R 362663 CDS YP_671193.1 110643463 4188832 3478961..3479170 1 NC_008253.1 hypothetical protein 3479170 4188832 ECP_3312 Escherichia coli 536 hypothetical protein YP_671193.1 3478961 D 362663 CDS YP_671194.1 110643464 4188833 complement(3479414..3479806) 1 NC_008253.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3479806 rpsI 4188833 rpsI Escherichia coli 536 30S ribosomal protein S9 YP_671194.1 3479414 R 362663 CDS YP_671195.1 110643465 4188834 complement(3479822..3480250) 1 NC_008253.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3480250 rplM 4188834 rplM Escherichia coli 536 50S ribosomal protein L13 YP_671195.1 3479822 R 362663 CDS YP_671196.1 110643466 4188835 complement(3480470..3481597) 1 NC_008253.1 ATPase 3481597 4188835 ECP_3315 Escherichia coli 536 ATPase YP_671196.1 3480470 R 362663 CDS YP_671197.1 110643467 4188836 3481791..3482189 1 NC_008253.1 cytochrome d ubiquinol oxidase subunit III 3482189 4188836 ECP_3316 Escherichia coli 536 cytochrome d ubiquinol oxidase subunit III YP_671197.1 3481791 D 362663 CDS YP_671198.1 110643468 4188837 3482343..3483710 1 NC_008253.1 serine endoprotease 3483710 4188837 ECP_3317 Escherichia coli 536 serine endoprotease YP_671198.1 3482343 D 362663 CDS YP_671199.1 110643469 4188838 3483800..3484867 1 NC_008253.1 serine endoprotease 3484867 4188838 ECP_3318 Escherichia coli 536 serine endoprotease YP_671199.1 3483800 D 362663 CDS YP_671200.1 110643470 4188839 complement(3484930..3485868) 1 NC_008253.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3485868 4188839 ECP_3319 Escherichia coli 536 malate dehydrogenase YP_671200.1 3484930 R 362663 CDS YP_671201.1 110643471 4188840 3486146..3486319 1 NC_008253.1 hypothetical protein 3486319 4188840 ECP_3320 Escherichia coli 536 hypothetical protein YP_671201.1 3486146 D 362663 CDS YP_671202.1 110643472 4188841 3486303..3486773 1 NC_008253.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3486773 4188841 ECP_3321 Escherichia coli 536 arginine repressor ArgR YP_671202.1 3486303 D 362663 CDS YP_671203.1 110643473 4188842 3487137..3487400 1 NC_008253.1 hypothetical protein 3487400 4188842 ECP_3322 Escherichia coli 536 hypothetical protein YP_671203.1 3487137 D 362663 CDS YP_671204.1 110643474 4188843 complement(3487455..3487727) 1 NC_008253.1 hypothetical protein 3487727 4188843 ECP_3323 Escherichia coli 536 hypothetical protein YP_671204.1 3487455 R 362663 CDS YP_671205.1 110643475 4190138 complement(3487819..3489786) 1 NC_008253.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3489786 4190138 ECP_3324 Escherichia coli 536 p-hydroxybenzoic acid efflux subunit AaeB YP_671205.1 3487819 R 362663 CDS YP_671206.1 110643476 4190139 complement(3489792..3490724) 1 NC_008253.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3490724 4190139 ECP_3325 Escherichia coli 536 p-hydroxybenzoic acid efflux subunit AaeA YP_671206.1 3489792 R 362663 CDS YP_671207.1 110643477 4190140 complement(3490732..3490935) 1 NC_008253.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3490935 4190140 ECP_3326 Escherichia coli 536 hypothetical protein YP_671207.1 3490732 R 362663 CDS YP_671208.1 110643478 4190141 3491118..3492047 1 NC_008253.1 DNA-binding transcriptional regulator 3492047 4190141 ECP_3327 Escherichia coli 536 DNA-binding transcriptional regulator YP_671208.1 3491118 D 362663 CDS YP_671209.1 110643479 4190142 complement(3492175..3493620) 1 NC_008253.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3493620 tldD 4190142 tldD Escherichia coli 536 protease TldD YP_671209.1 3492175 R 362663 CDS YP_671210.1 110643480 4190143 complement(3493776..3497576) 1 NC_008253.1 hypothetical protein 3497576 4190143 ECP_3329 Escherichia coli 536 hypothetical protein YP_671210.1 3493776 R 362663 CDS YP_671211.1 110643481 4190144 complement(3497644..3499113) 1 NC_008253.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3499113 4190144 ECP_3330 Escherichia coli 536 ribonuclease G YP_671211.1 3497644 R 362663 CDS YP_671212.1 110643482 4190145 complement(3499103..3499696) 1 NC_008253.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3499696 4190145 ECP_3331 Escherichia coli 536 Maf-like protein YP_671212.1 3499103 R 362663 CDS YP_671213.1 110643483 4190146 complement(3499705..3500193) 1 NC_008253.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3500193 4190146 ECP_3332 Escherichia coli 536 rod shape-determining protein MreD YP_671213.1 3499705 R 362663 CDS YP_671214.1 110643484 4190147 complement(3500193..3501296) 1 NC_008253.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3501296 4190147 ECP_3333 Escherichia coli 536 rod shape-determining protein MreC YP_671214.1 3500193 R 362663 CDS YP_671215.1 110643485 4190148 complement(3501362..3502405) 1 NC_008253.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3502405 4190148 ECP_3334 Escherichia coli 536 rod shape-determining protein MreB YP_671215.1 3501362 R 362663 CDS YP_671216.1 110643486 4190149 3502513..3502701 1 NC_008253.1 hypothetical protein 3502701 4190149 ECP_3335 Escherichia coli 536 hypothetical protein YP_671216.1 3502513 D 362663 CDS YP_671217.1 110643487 4190150 complement(3502710..3504650) 1 NC_008253.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3504650 4190150 ECP_3336 Escherichia coli 536 regulatory protein CsrD YP_671217.1 3502710 R 362663 CDS YP_671218.1 110643488 4190151 3504802..3505776 1 NC_008253.1 zinc-binding dehydrogenase 3505776 4190151 ECP_3337 Escherichia coli 536 zinc-binding dehydrogenase YP_671218.1 3504802 D 362663 CDS YP_671219.1 110643489 4190152 3505813..3505977 1 NC_008253.1 hypothetical protein 3505977 4190152 ECP_3338 Escherichia coli 536 hypothetical protein YP_671219.1 3505813 D 362663 CDS YP_671220.1 110643490 4190153 3506185..3506349 1 NC_008253.1 hypothetical protein 3506349 4190153 ECP_3339 Escherichia coli 536 hypothetical protein YP_671220.1 3506185 D 362663 CDS YP_671221.1 110643491 4190154 3506754..3507224 1 NC_008253.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3507224 4190154 ECP_3340 Escherichia coli 536 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_671221.1 3506754 D 362663 CDS YP_671222.1 110643492 4190155 3507235..3508584 1 NC_008253.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3508584 4190155 ECP_3341 Escherichia coli 536 acetyl-CoA carboxylase biotin carboxylase subunit YP_671222.1 3507235 D 362663 CDS YP_671223.1 110643493 4190156 complement(3508676..3509722) 1 NC_008253.1 hypothetical protein 3509722 4190156 ECP_3342 Escherichia coli 536 hypothetical protein YP_671223.1 3508676 R 362663 CDS YP_671224.1 110643494 4190157 complement(3509719..3510681) 1 NC_008253.1 ribokinase sugar kinase 3510681 4190157 ECP_3343 Escherichia coli 536 ribokinase sugar kinase YP_671224.1 3509719 R 362663 CDS YP_671225.1 110643495 4188943 complement(3510703..3511692) 1 NC_008253.1 sugar uptake ABC transporter permease 3511692 4188943 ECP_3344 Escherichia coli 536 sugar uptake ABC transporter permease YP_671225.1 3510703 R 362663 CDS YP_671226.1 110643496 4188944 complement(3511693..3513192) 1 NC_008253.1 sugar uptake ABC transporter ATP-binding protein 3513192 4188944 ECP_3345 Escherichia coli 536 sugar uptake ABC transporter ATP-binding protein YP_671226.1 3511693 R 362663 CDS YP_671227.1 110643497 4188945 complement(3513253..3514143) 1 NC_008253.1 sugar uptake ABC transporter periplasmic solute-binding protein 3514143 4188945 ECP_3346 Escherichia coli 536 sugar uptake ABC transporter periplasmic solute-binding protein YP_671227.1 3513253 R 362663 CDS YP_671228.1 110643498 4188946 complement(3514179..3515033) 1 NC_008253.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3515033 gatY 4188946 gatY Escherichia coli 536 tagatose-bisphosphate aldolase YP_671228.1 3514179 R 362663 CDS YP_671229.1 110643499 4188947 3515375..3516205 1 NC_008253.1 DeoR family regulatory protein 3516205 4188947 ECP_3348 Escherichia coli 536 DeoR family regulatory protein YP_671229.1 3515375 D 362663 CDS YP_671230.1 110643500 4188948 3516216..3517172 1 NC_008253.1 ribokinase sugar kinase 3517172 4188948 ECP_3349 Escherichia coli 536 ribokinase sugar kinase YP_671230.1 3516216 D 362663 CDS YP_671231.1 110643501 4188949 3517265..3517507 1 NC_008253.1 hypothetical protein 3517507 4188949 ECP_3350 Escherichia coli 536 hypothetical protein YP_671231.1 3517265 D 362663 CDS YP_671232.1 110643502 4188950 3517497..3518948 1 NC_008253.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3518948 panF 4188950 panF Escherichia coli 536 sodium/panthothenate symporter YP_671232.1 3517497 D 362663 CDS YP_671233.1 110643503 4188951 3518960..3519841 1 NC_008253.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3519841 prmA 4188951 prmA Escherichia coli 536 50S ribosomal protein L11 methyltransferase YP_671233.1 3518960 D 362663 CDS YP_671234.1 110643504 4188952 3520170..3521135 1 NC_008253.1 tRNA-dihydrouridine synthase B 3521135 4188952 ECP_3353 Escherichia coli 536 tRNA-dihydrouridine synthase B YP_671234.1 3520170 D 362663 CDS YP_671235.1 110643505 4188953 3521161..3521457 1 NC_008253.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3521457 fis 4188953 fis Escherichia coli 536 DNA-binding protein Fis YP_671235.1 3521161 D 362663 CDS YP_671236.1 110643506 4188954 3521543..3522427 1 NC_008253.1 methyltransferase 3522427 4188954 ECP_3355 Escherichia coli 536 methyltransferase YP_671236.1 3521543 D 362663 CDS YP_671237.1 110643507 4188955 3522511..3522690 1 NC_008253.1 hypothetical protein 3522690 4188955 ECP_3356 Escherichia coli 536 hypothetical protein YP_671237.1 3522511 D 362663 CDS YP_671238.1 110643508 4188956 complement(3522693..3523355) 1 NC_008253.1 DNA-binding transcriptional regulator EnvR 3523355 4188956 ECP_3357 Escherichia coli 536 DNA-binding transcriptional regulator EnvR YP_671238.1 3522693 R 362663 CDS YP_671239.1 110643509 4188957 complement(3523556..3523765) 1 NC_008253.1 hypothetical protein 3523765 4188957 ECP_3358 Escherichia coli 536 hypothetical protein YP_671239.1 3523556 R 362663 CDS YP_671240.1 110643510 4188958 3523754..3524911 1 NC_008253.1 acriflavine resistance protein E 3524911 4188958 ECP_3359 Escherichia coli 536 acriflavine resistance protein E YP_671240.1 3523754 D 362663 CDS YP_671241.1 110643511 4188959 3524923..3528027 1 NC_008253.1 acriflavine resistance protein F 3528027 4188959 ECP_3360 Escherichia coli 536 acriflavine resistance protein F YP_671241.1 3524923 D 362663 CDS YP_671242.1 110643512 4188960 3528280..3528501 1 NC_008253.1 hypothetical protein 3528501 4188960 ECP_3361 Escherichia coli 536 hypothetical protein YP_671242.1 3528280 D 362663 CDS YP_671243.1 110643513 4188961 3528727..3528903 1 NC_008253.1 hypothetical protein 3528903 4188961 ECP_3362 Escherichia coli 536 hypothetical protein YP_671243.1 3528727 D 362663 CDS YP_671244.1 110643514 4189258 3528932..3529957 1 NC_008253.1 amino-acid ABC transporter binding protein YhdW 3529957 4189258 ECP_3363 Escherichia coli 536 amino-acid ABC transporter binding protein YhdW YP_671244.1 3528932 D 362663 CDS YP_671245.1 110643515 4189259 3530025..3531206 1 NC_008253.1 amino acid ABC transporter permease 3531206 4189259 ECP_3364 Escherichia coli 536 amino acid ABC transporter permease YP_671245.1 3530025 D 362663 CDS YP_671246.1 110643516 4189260 3531216..3532319 1 NC_008253.1 amino acid ABC transporter permease 3532319 4189260 ECP_3365 Escherichia coli 536 amino acid ABC transporter permease YP_671246.1 3531216 D 362663 CDS YP_671247.1 110643517 4189261 3532327..3533085 1 NC_008253.1 amino acid ABC transporter ATP-binding protein 3533085 4189261 ECP_3366 Escherichia coli 536 amino acid ABC transporter ATP-binding protein YP_671247.1 3532327 D 362663 CDS YP_671248.1 110643518 4189262 3538877..3539431 1 NC_008253.1 transferase 3539431 4189262 ECP_3367 Escherichia coli 536 transferase YP_671248.1 3538877 D 362663 CDS YP_671249.1 110643519 4189263 complement(3539407..3539664) 1 NC_008253.1 hypothetical protein 3539664 4189263 ECP_3368 Escherichia coli 536 hypothetical protein YP_671249.1 3539407 R 362663 CDS YP_671250.1 110643520 4189264 complement(3539661..3540479) 1 NC_008253.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3540479 aroE 4189264 aroE Escherichia coli 536 shikimate 5-dehydrogenase YP_671250.1 3539661 R 362663 CDS YP_671251.1 110643521 4189265 complement(3540484..3541101) 1 NC_008253.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3541101 4189265 ECP_3370 Escherichia coli 536 ribosome maturation factor YP_671251.1 3540484 R 362663 CDS YP_671252.1 110643522 4189266 complement(3541061..3541603) 1 NC_008253.1 DNA topoisomerase 3541603 4189266 ECP_3371 Escherichia coli 536 DNA topoisomerase YP_671252.1 3541061 R 362663 CDS YP_671253.1 110643523 4189267 complement(3541632..3542105) 1 NC_008253.1 hypothetical protein smg; hypothetical protein 3542105 4189267 ECP_3372 Escherichia coli 536 hypothetical protein YP_671253.1 3541632 R 362663 CDS YP_671254.1 110643524 4189268 complement(3542077..3543201) 1 NC_008253.1 DNA protecting protein DprA 3543201 4189268 ECP_3373 Escherichia coli 536 DNA protecting protein DprA YP_671254.1 3542077 R 362663 CDS YP_671255.1 110643525 4189269 3543331..3543840 1 NC_008253.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3543840 def 4189269 def Escherichia coli 536 peptide deformylase YP_671255.1 3543331 D 362663 CDS YP_671256.1 110643526 4189270 3543855..3544802 1 NC_008253.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3544802 fmt 4189270 fmt Escherichia coli 536 methionyl-tRNA formyltransferase YP_671256.1 3543855 D 362663 CDS YP_671257.1 110643527 4189271 3544854..3546143 1 NC_008253.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3546143 4189271 ECP_3376 Escherichia coli 536 16S rRNA methyltransferase GidB YP_671257.1 3544854 D 362663 CDS YP_671258.1 110643528 4189272 3546165..3547541 1 NC_008253.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3547541 trkA 4189272 trkA Escherichia coli 536 potassium transporter peripheral membrane protein YP_671258.1 3546165 D 362663 CDS YP_671259.1 110643529 4189273 3547671..3548084 1 NC_008253.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3548084 mscL 4189273 mscL Escherichia coli 536 large-conductance mechanosensitive channel YP_671259.1 3547671 D 362663 CDS YP_671260.1 110643530 4189274 complement(3548081..3548299) 1 NC_008253.1 hypothetical protein 3548299 4189274 ECP_3379 Escherichia coli 536 hypothetical protein YP_671260.1 3548081 R 362663 CDS YP_671261.1 110643531 4189275 complement(3548355..3548780) 1 NC_008253.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3548780 zntR 4189275 zntR Escherichia coli 536 zinc-responsive transcriptional regulator YP_671261.1 3548355 R 362663 CDS YP_671262.1 110643532 4189276 complement(3548791..3549159) 1 NC_008253.1 hypothetical protein 3549159 4189276 ECP_3381 Escherichia coli 536 hypothetical protein YP_671262.1 3548791 R 362663 CDS YP_671263.1 110643533 4189277 complement(3549266..3549649) 1 NC_008253.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3549649 rplQ 4189277 rplQ Escherichia coli 536 50S ribosomal protein L17 YP_671263.1 3549266 R 362663 CDS YP_671264.1 110643534 4191209 complement(3549690..3550679) 1 NC_008253.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3550679 4191209 ECP_3383 Escherichia coli 536 DNA-directed RNA polymerase subunit alpha YP_671264.1 3549690 R 362663 CDS YP_671265.1 110643535 4191210 complement(3550705..3551325) 1 NC_008253.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3551325 rpsD 4191210 rpsD Escherichia coli 536 30S ribosomal protein S4 YP_671265.1 3550705 R 362663 CDS YP_671266.1 110643536 4191211 complement(3551359..3551748) 1 NC_008253.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3551748 4191211 ECP_3385 Escherichia coli 536 30S ribosomal protein S11 YP_671266.1 3551359 R 362663 CDS YP_671267.1 110643537 4191212 complement(3551765..3552121) 1 NC_008253.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3552121 rpsM 4191212 rpsM Escherichia coli 536 30S ribosomal protein S13 YP_671267.1 3551765 R 362663 CDS YP_671268.1 110643538 4191213 complement(3552268..3552384) 1 NC_008253.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 3552384 rpmJ 4191213 rpmJ Escherichia coli 536 50S ribosomal protein L36 YP_671268.1 3552268 R 362663 CDS YP_671269.1 110643539 4191214 complement(3552416..3553747) 1 NC_008253.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3553747 secY 4191214 secY Escherichia coli 536 preprotein translocase subunit SecY YP_671269.1 3552416 R 362663 CDS YP_671270.1 110643540 4191215 complement(3553755..3554189) 1 NC_008253.1 late assembly protein; 50S ribosomal protein L15 3554189 rplO 4191215 rplO Escherichia coli 536 50S ribosomal protein L15 YP_671270.1 3553755 R 362663 CDS YP_671271.1 110643541 4191216 complement(3554193..3554372) 1 NC_008253.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3554372 rpmD 4191216 rpmD Escherichia coli 536 50S ribosomal protein L30 YP_671271.1 3554193 R 362663 CDS YP_671272.1 110643542 4191217 complement(3554376..3554879) 1 NC_008253.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3554879 rpsE 4191217 rpsE Escherichia coli 536 30S ribosomal protein S5 YP_671272.1 3554376 R 362663 CDS YP_671273.1 110643543 4191218 complement(3554894..3555247) 1 NC_008253.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3555247 rplR 4191218 rplR Escherichia coli 536 50S ribosomal protein L18 YP_671273.1 3554894 R 362663 CDS YP_671274.1 110643544 4191219 complement(3555257..3555790) 1 NC_008253.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3555790 rplF 4191219 rplF Escherichia coli 536 50S ribosomal protein L6 YP_671274.1 3555257 R 362663 CDS YP_671275.1 110643545 4191220 complement(3555803..3556195) 1 NC_008253.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3556195 rpsH 4191220 rpsH Escherichia coli 536 30S ribosomal protein S8 YP_671275.1 3555803 R 362663 CDS YP_671276.1 110643546 4191221 complement(3556229..3556534) 1 NC_008253.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3556534 rpsN 4191221 rpsN Escherichia coli 536 30S ribosomal protein S14 YP_671276.1 3556229 R 362663 CDS YP_671277.1 110643547 4191222 complement(3556549..3557088) 1 NC_008253.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3557088 rplE 4191222 rplE Escherichia coli 536 50S ribosomal protein L5 YP_671277.1 3556549 R 362663 CDS YP_671278.1 110643548 4191223 complement(3557103..3557417) 1 NC_008253.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3557417 rplX 4191223 rplX Escherichia coli 536 50S ribosomal protein L24 YP_671278.1 3557103 R 362663 CDS YP_671279.1 110643549 4191224 complement(3557428..3557799) 1 NC_008253.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3557799 rplN 4191224 rplN Escherichia coli 536 50S ribosomal protein L14 YP_671279.1 3557428 R 362663 CDS YP_671280.1 110643550 4191225 complement(3557964..3558218) 1 NC_008253.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3558218 rpsQ 4191225 rpsQ Escherichia coli 536 30S ribosomal protein S17 YP_671280.1 3557964 R 362663 CDS YP_671281.1 110643551 4191226 complement(3558218..3558409) 1 NC_008253.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3558409 4191226 ECP_3400 Escherichia coli 536 50S ribosomal protein L29 YP_671281.1 3558218 R 362663 CDS YP_671282.1 110643552 4191227 complement(3558409..3558819) 1 NC_008253.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3558819 rplP 4191227 rplP Escherichia coli 536 50S ribosomal protein L16 YP_671282.1 3558409 R 362663 CDS YP_671283.1 110643553 4191480 complement(3558832..3559533) 1 NC_008253.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3559533 rpsC 4191480 rpsC Escherichia coli 536 30S ribosomal protein S3 YP_671283.1 3558832 R 362663 CDS YP_671284.1 110643554 4191481 complement(3559551..3559883) 1 NC_008253.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3559883 rplV 4191481 rplV Escherichia coli 536 50S ribosomal protein L22 YP_671284.1 3559551 R 362663 CDS YP_671285.1 110643555 4191482 complement(3559898..3560176) 1 NC_008253.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3560176 rpsS 4191482 rpsS Escherichia coli 536 30S ribosomal protein S19 YP_671285.1 3559898 R 362663 CDS YP_671286.1 110643556 4191483 complement(3560193..3561014) 1 NC_008253.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3561014 rplB 4191483 rplB Escherichia coli 536 50S ribosomal protein L2 YP_671286.1 3560193 R 362663 CDS YP_671287.1 110643557 4191484 complement(3561032..3561334) 1 NC_008253.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3561334 rplW 4191484 rplW Escherichia coli 536 50S ribosomal protein L23 YP_671287.1 3561032 R 362663 CDS YP_671288.1 110643558 4191485 complement(3561331..3561936) 1 NC_008253.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3561936 rplD 4191485 rplD Escherichia coli 536 50S ribosomal protein L4 YP_671288.1 3561331 R 362663 CDS YP_671289.1 110643559 4191486 complement(3561947..3562576) 1 NC_008253.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3562576 rplC 4191486 rplC Escherichia coli 536 50S ribosomal protein L3 YP_671289.1 3561947 R 362663 CDS YP_671290.1 110643560 4191487 complement(3562609..3562920) 1 NC_008253.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3562920 rpsJ 4191487 rpsJ Escherichia coli 536 30S ribosomal protein S10 YP_671290.1 3562609 R 362663 CDS YP_671291.1 110643561 4191488 complement(3563158..3563577) 1 NC_008253.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 3563577 4191488 ECP_3410 Escherichia coli 536 chromosome replication protein PioO YP_671291.1 3563158 R 362663 CDS YP_671292.1 110643562 4191489 complement(3563579..3565048) 1 NC_008253.1 general secretion pathway protein A 3565048 4191489 ECP_3411 Escherichia coli 536 general secretion pathway protein A YP_671292.1 3563579 R 362663 CDS YP_671293.1 110643563 4191490 3565228..3566043 1 NC_008253.1 general secretion pathway protein C 3566043 4191490 ECP_3412 Escherichia coli 536 general secretion pathway protein C YP_671293.1 3565228 D 362663 CDS YP_671294.1 110643564 4191491 3566015..3567979 1 NC_008253.1 general secretion pathway protein D 3567979 4191491 ECP_3413 Escherichia coli 536 general secretion pathway protein D YP_671294.1 3566015 D 362663 CDS YP_671295.1 110643565 4191492 3567989..3569470 1 NC_008253.1 general secretion pathway protein E 3569470 4191492 ECP_3414 Escherichia coli 536 general secretion pathway protein E YP_671295.1 3567989 D 362663 CDS YP_671296.1 110643566 4191493 3569467..3570663 1 NC_008253.1 general secretion pathway protein F 3570663 4191493 ECP_3415 Escherichia coli 536 general secretion pathway protein F YP_671296.1 3569467 D 362663 CDS YP_671297.1 110643567 4191494 3570673..3571110 1 NC_008253.1 general secretion pathway protein G 3571110 4191494 ECP_3416 Escherichia coli 536 general secretion pathway protein G YP_671297.1 3570673 D 362663 CDS YP_671298.1 110643568 4191495 3571118..3571627 1 NC_008253.1 general secretion pathway protein H 3571627 4191495 ECP_3417 Escherichia coli 536 general secretion pathway protein H YP_671298.1 3571118 D 362663 CDS YP_671299.1 110643569 4191496 3571585..3572019 1 NC_008253.1 general secretion pathway protein I 3572019 4191496 ECP_3418 Escherichia coli 536 general secretion pathway protein I YP_671299.1 3571585 D 362663 CDS YP_671300.1 110643570 4191497 3572012..3572599 1 NC_008253.1 general secretion pathway protein J 3572599 4191497 ECP_3419 Escherichia coli 536 general secretion pathway protein J YP_671300.1 3572012 D 362663 CDS YP_671301.1 110643571 4191498 3572592..3573575 1 NC_008253.1 general secretion pathway protein K 3573575 4191498 ECP_3420 Escherichia coli 536 general secretion pathway protein K YP_671301.1 3572592 D 362663 CDS YP_671302.1 110643572 4191499 3573590..3574753 1 NC_008253.1 general secretion pathway protein L 3574753 4191499 ECP_3421 Escherichia coli 536 general secretion pathway protein L YP_671302.1 3573590 D 362663 CDS YP_671303.1 110643573 4190002 3574750..3575244 1 NC_008253.1 general secretion pathway protein M 3575244 4190002 ECP_3422 Escherichia coli 536 general secretion pathway protein M YP_671303.1 3574750 D 362663 CDS YP_671304.1 110643574 4190003 3575271..3576293 1 NC_008253.1 transposase for insertion sequence IS100 3576293 4190003 ECP_3423 Escherichia coli 536 transposase for insertion sequence IS100 YP_671304.1 3575271 D 362663 CDS YP_671305.1 110643575 4190004 3576293..3577072 1 NC_008253.1 transposase/IS protein 3577072 4190004 ECP_3424 Escherichia coli 536 transposase/IS protein YP_671305.1 3576293 D 362663 CDS YP_671306.1 110643576 4190005 3577170..3577847 1 NC_008253.1 type 4 prepilin-like proteins leader peptide processing enzyme 3577847 4190005 ECP_3425 Escherichia coli 536 type 4 prepilin-like proteins leader peptide processing enzyme YP_671306.1 3577170 D 362663 CDS YP_671307.1 110643577 4190006 complement(3577876..3578352) 1 NC_008253.1 iron storage protein; bacterioferritin 3578352 4190006 ECP_3426 Escherichia coli 536 bacterioferritin YP_671307.1 3577876 R 362663 CDS YP_671308.1 110643578 4190007 complement(3578424..3578618) 1 NC_008253.1 bacterioferritin-associated ferredoxin 3578618 4190007 ECP_3427 Escherichia coli 536 bacterioferritin-associated ferredoxin YP_671308.1 3578424 R 362663 CDS YP_671309.1 110643579 4190008 complement(3578787..3581489) 1 NC_008253.1 bifunctional chitinase/lysozyme 3581489 4190008 ECP_3428 Escherichia coli 536 bifunctional chitinase/lysozyme YP_671309.1 3578787 R 362663 CDS YP_671310.1 110643580 4190009 complement(3581781..3582965) 1 NC_008253.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3582965 4190009 ECP_3429 Escherichia coli 536 elongation factor Tu YP_671310.1 3581781 R 362663 CDS YP_671311.1 110643581 4190010 complement(3583036..3585150) 1 NC_008253.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3585150 4190010 ECP_3430 Escherichia coli 536 elongation factor G YP_671311.1 3583036 R 362663 CDS YP_671312.1 110643582 4190011 complement(3585247..3585717) 1 NC_008253.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3585717 4190011 ECP_3431 Escherichia coli 536 30S ribosomal protein S7 YP_671312.1 3585247 R 362663 CDS YP_671313.1 110643583 4190012 complement(3585814..3586188) 1 NC_008253.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3586188 rpsL 4190012 rpsL Escherichia coli 536 30S ribosomal protein S12 YP_671313.1 3585814 R 362663 CDS YP_671314.1 110643584 4190013 complement(3586314..3586601) 1 NC_008253.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3586601 4190013 ECP_3433 Escherichia coli 536 sulfur transfer complex subunit TusB YP_671314.1 3586314 R 362663 CDS YP_671315.1 110643585 4190014 complement(3586609..3586968) 1 NC_008253.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3586968 4190014 ECP_3434 Escherichia coli 536 sulfur relay protein TusC YP_671315.1 3586609 R 362663 CDS YP_671316.1 110643586 4190015 complement(3586968..3587354) 1 NC_008253.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3587354 4190015 ECP_3435 Escherichia coli 536 sulfur transfer complex subunit TusD YP_671316.1 3586968 R 362663 CDS YP_671317.1 110643587 4190016 complement(3587354..3588076) 1 NC_008253.1 hypothetical protein 3588076 4190016 ECP_3436 Escherichia coli 536 hypothetical protein YP_671317.1 3587354 R 362663 CDS YP_671318.1 110643588 4190017 complement(3588243..3589055) 1 NC_008253.1 rotamase; FKBP-type peptidylprolyl isomerase 3589055 4190017 ECP_3437 Escherichia coli 536 FKBP-type peptidylprolyl isomerase YP_671318.1 3588243 R 362663 CDS YP_671319.1 110643589 4190018 complement(3589555..3590145) 1 NC_008253.1 rotamase; FKBP-type peptidylprolyl isomerase 3590145 4190018 ECP_3438 Escherichia coli 536 FKBP-type peptidylprolyl isomerase YP_671319.1 3589555 R 362663 CDS YP_671320.1 110643590 4190019 complement(3590240..3590440) 1 NC_008253.1 hypothetical protein 3590440 4190019 ECP_3439 Escherichia coli 536 hypothetical protein YP_671320.1 3590240 R 362663 CDS YP_671321.1 110643591 4187871 complement(3592255..3592806) 1 NC_008253.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3592806 4187871 ECP_3442 Escherichia coli 536 glutathione-regulated potassium-efflux system ancillary protein KefG YP_671321.1 3592255 R 362663 CDS YP_671322.1 110643592 4187872 3592937..3594850 1 NC_008253.1 ABC transporter ATP-binding protein 3594850 4187872 ECP_3443 Escherichia coli 536 ABC transporter ATP-binding protein YP_671322.1 3592937 D 362663 CDS YP_671323.1 110643593 4187873 3594850..3595872 1 NC_008253.1 hydrolase 3595872 4187873 ECP_3444 Escherichia coli 536 hydrolase YP_671323.1 3594850 D 362663 CDS YP_671324.1 110643594 4187874 3595866..3596084 1 NC_008253.1 hypothetical protein 3596084 4187874 ECP_3445 Escherichia coli 536 hypothetical protein YP_671324.1 3595866 D 362663 CDS YP_671325.1 110643595 4187875 3596138..3597007 1 NC_008253.1 phosphoribulokinase 3597007 4187875 ECP_3446 Escherichia coli 536 phosphoribulokinase YP_671325.1 3596138 D 362663 CDS YP_671326.1 110643596 4187876 complement(3597062..3597466) 1 NC_008253.1 hypothetical protein 3597466 4187876 ECP_3447 Escherichia coli 536 hypothetical protein YP_671326.1 3597062 R 362663 CDS YP_671327.1 110643597 4187877 3597768..3598400 1 NC_008253.1 catabolite gene activator; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3598400 4187877 ECP_3448 Escherichia coli 536 cAMP-regulatory protein YP_671327.1 3597768 D 362663 CDS YP_671328.1 110643598 4187878 3598451..3600541 1 NC_008253.1 hypothetical protein 3600541 4187878 ECP_3449 Escherichia coli 536 hypothetical protein YP_671328.1 3598451 D 362663 CDS YP_671329.1 110643599 4187879 complement(3600619..3601839) 1 NC_008253.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 3601839 argD 4187879 argD Escherichia coli 536 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_671329.1 3600619 R 362663 CDS YP_671330.1 110643600 4187880 complement(3601925..3602488) 1 NC_008253.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3602488 4187880 ECP_3451 Escherichia coli 536 para-aminobenzoate synthase component II YP_671330.1 3601925 R 362663 CDS YP_671331.1 110643601 4187881 complement(3602520..3603122) 1 NC_008253.1 cell filamentation protein Fic 3603122 4187881 ECP_3452 Escherichia coli 536 cell filamentation protein Fic YP_671331.1 3602520 R 362663 CDS YP_671332.1 110643602 4187882 complement(3603112..3603279) 1 NC_008253.1 hypothetical protein 3603279 4187882 ECP_3453 Escherichia coli 536 hypothetical protein YP_671332.1 3603112 R 362663 CDS YP_671333.1 110643603 4187883 complement(3603384..3603956) 1 NC_008253.1 peptidyl-prolyl cis-trans isomerase A 3603956 4187883 ECP_3454 Escherichia coli 536 peptidyl-prolyl cis-trans isomerase A YP_671333.1 3603384 R 362663 CDS YP_671334.1 110643604 4187884 3604227..3605408 1 NC_008253.1 hypothetical protein 3605408 4187884 ECP_3455 Escherichia coli 536 hypothetical protein YP_671334.1 3604227 D 362663 CDS YP_671335.1 110643605 4187885 3605670..3608213 1 NC_008253.1 nitrite reductase [NAD(P)H] large subunit 3608213 4187885 ECP_3456 Escherichia coli 536 nitrite reductase [NAD(P)H] large subunit YP_671335.1 3605670 D 362663 CDS YP_671336.1 110643606 4187886 3608210..3608536 1 NC_008253.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3608536 nirD 4187886 nirD Escherichia coli 536 nitrite reductase small subunit YP_671336.1 3608210 D 362663 CDS YP_671337.1 110643607 4189031 3608662..3609468 1 NC_008253.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3609468 4189031 ECP_3458 Escherichia coli 536 nitrite transporter NirC YP_671337.1 3608662 D 362663 CDS YP_671338.1 110643608 4189032 3609487..3610860 1 NC_008253.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3610860 cysG 4189032 cysG Escherichia coli 536 siroheme synthase YP_671338.1 3609487 D 362663 CDS YP_671339.1 110643609 4189033 3611112..3611279 1 NC_008253.1 hypothetical protein 3611279 4189033 ECP_3460 Escherichia coli 536 hypothetical protein YP_671339.1 3611112 D 362663 CDS YP_671340.1 110643610 4189034 complement(3611386..3612471) 1 NC_008253.1 hypothetical protein 3612471 4189034 ECP_3461 Escherichia coli 536 hypothetical protein YP_671340.1 3611386 R 362663 CDS YP_671341.1 110643611 4189035 complement(3612483..3613787) 1 NC_008253.1 hypothetical protein 3613787 4189035 ECP_3462 Escherichia coli 536 hypothetical protein YP_671341.1 3612483 R 362663 CDS YP_671342.1 110643612 4189036 complement(3613799..3614152) 1 NC_008253.1 hypothetical protein 3614152 4189036 ECP_3463 Escherichia coli 536 hypothetical protein YP_671342.1 3613799 R 362663 CDS YP_671343.1 110643613 4189037 complement(3614163..3615041) 1 NC_008253.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3615041 4189037 ECP_3464 Escherichia coli 536 hydrolase YP_671343.1 3614163 R 362663 CDS YP_671344.1 110643614 4189038 complement(3615038..3616264) 1 NC_008253.1 mutase 3616264 4189038 ECP_3465 Escherichia coli 536 mutase YP_671344.1 3615038 R 362663 CDS YP_671345.1 110643615 4189039 complement(3616265..3617428) 1 NC_008253.1 hypothetical protein 3617428 4189039 ECP_3466 Escherichia coli 536 hypothetical protein YP_671345.1 3616265 R 362663 CDS YP_671346.1 110643616 4189040 complement(3617512..3617874) 1 NC_008253.1 hypothetical protein 3617874 4189040 ECP_3467 Escherichia coli 536 hypothetical protein YP_671346.1 3617512 R 362663 CDS YP_671347.1 110643617 4189041 complement(3617891..3618796) 1 NC_008253.1 hypothetical protein 3618796 4189041 ECP_3468 Escherichia coli 536 hypothetical protein YP_671347.1 3617891 R 362663 CDS YP_671348.1 110643618 4189042 complement(3618956..3619960) 1 NC_008253.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3619960 4189042 ECP_3469 Escherichia coli 536 tryptophanyl-tRNA synthetase YP_671348.1 3618956 R 362663 CDS YP_671349.1 110643619 4189043 complement(3619953..3620711) 1 NC_008253.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3620711 4189043 ECP_3470 Escherichia coli 536 phosphoglycolate phosphatase YP_671349.1 3619953 R 362663 CDS YP_671350.1 110643620 4189044 complement(3620704..3621381) 1 NC_008253.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3621381 4189044 ECP_3471 Escherichia coli 536 ribulose-phosphate 3-epimerase YP_671350.1 3620704 R 362663 CDS YP_671351.1 110643621 4189045 complement(3621399..3622235) 1 NC_008253.1 DNA adenine methylase 3622235 4189045 ECP_3472 Escherichia coli 536 DNA adenine methylase YP_671351.1 3621399 R 362663 CDS YP_671352.1 110643622 4191326 complement(3623722..3624810) 1 NC_008253.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3624810 aroB 4191326 aroB Escherichia coli 536 3-dehydroquinate synthase YP_671352.1 3623722 R 362663 CDS YP_671353.2 229560210 4191327 complement(3624867..3625388) 1 NC_008253.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3625388 aroK 4191327 aroK Escherichia coli 536 shikimate kinase I YP_671353.2 3624867 R 362663 CDS YP_671354.1 110643624 4191328 complement(3625789..3627027) 1 NC_008253.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3627027 hofQ 4191328 hofQ Escherichia coli 536 outer membrane porin HofQ YP_671354.1 3625789 R 362663 CDS YP_671355.1 110643625 4191329 complement(3626939..3627343) 1 NC_008253.1 hypothetical protein 3627343 4191329 ECP_3478 Escherichia coli 536 hypothetical protein YP_671355.1 3626939 R 362663 CDS YP_671356.1 110643626 4191330 complement(3627333..3627773) 1 NC_008253.1 hypothetical protein 3627773 4191330 ECP_3479 Escherichia coli 536 hypothetical protein YP_671356.1 3627333 R 362663 CDS YP_671357.1 110643627 4191331 complement(3627757..3628296) 1 NC_008253.1 hypothetical protein 3628296 4191331 ECP_3480 Escherichia coli 536 hypothetical protein YP_671357.1 3627757 R 362663 CDS YP_671358.1 110643628 4191332 complement(3628296..3629075) 1 NC_008253.1 hypothetical protein 3629075 4191332 ECP_3481 Escherichia coli 536 hypothetical protein YP_671358.1 3628296 R 362663 CDS YP_671359.1 110643629 4191333 3629195..3631747 1 NC_008253.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3631747 mrcA 4191333 mrcA Escherichia coli 536 peptidoglycan synthetase YP_671359.1 3629195 D 362663 CDS YP_671360.1 110643630 4191334 complement(3631914..3632474) 1 NC_008253.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3632474 nudE 4191334 nudE Escherichia coli 536 ADP-ribose diphosphatase NudE YP_671360.1 3631914 R 362663 CDS YP_671361.1 110643631 4191335 3632794..3634929 1 NC_008253.1 membrane protein IgaA 3634929 4191335 ECP_3484 Escherichia coli 536 membrane protein IgaA YP_671361.1 3632794 D 362663 CDS YP_671362.1 110643632 4191336 3634994..3635662 1 NC_008253.1 hydrolase 3635662 4191336 ECP_3485 Escherichia coli 536 hydrolase YP_671362.1 3634994 D 362663 CDS YP_671363.1 110643633 4191337 3635673..3636074 1 NC_008253.1 ribosome-associated heat shock protein Hsp15 3636074 4191337 ECP_3486 Escherichia coli 536 ribosome-associated heat shock protein Hsp15 YP_671363.1 3635673 D 362663 CDS YP_671364.1 110643634 4191338 3636093..3636977 1 NC_008253.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3636977 hslO 4191338 hslO Escherichia coli 536 Hsp33-like chaperonin YP_671364.1 3636093 D 362663 CDS YP_671365.1 110643635 4191339 complement(3637040..3638764) 1 NC_008253.1 hypothetical protein 3638764 4191339 ECP_3488 Escherichia coli 536 hypothetical protein YP_671365.1 3637040 R 362663 CDS YP_671366.1 110643636 4191340 3639143..3640765 1 NC_008253.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3640765 4191340 ECP_3489 Escherichia coli 536 phosphoenolpyruvate carboxykinase YP_671366.1 3639143 D 362663 CDS YP_671367.1 110643637 4191341 complement(3640842..3642194) 1 NC_008253.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3642194 envZ 4191341 envZ Escherichia coli 536 osmolarity sensor protein YP_671367.1 3640842 R 362663 CDS YP_671368.1 110643638 4191342 complement(3642191..3642910) 1 NC_008253.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3642910 ompR 4191342 ompR Escherichia coli 536 osmolarity response regulator YP_671368.1 3642191 R 362663 CDS YP_671369.1 110643639 4191343 3643138..3643614 1 NC_008253.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3643614 greB 4191343 greB Escherichia coli 536 transcription elongation factor GreB YP_671369.1 3643138 D 362663 CDS YP_671370.1 110643640 4191344 3643711..3646032 1 NC_008253.1 S1 RNA-binding domain-containing protein 3646032 4191344 ECP_3493 Escherichia coli 536 S1 RNA-binding domain-containing protein YP_671370.1 3643711 D 362663 CDS YP_671371.1 110643641 4191345 3646470..3646697 1 NC_008253.1 ferrous iron transport protein A 3646697 feoA 4191345 feoA Escherichia coli 536 ferrous iron transport protein A YP_671371.1 3646470 D 362663 CDS YP_671372.1 110643642 4191346 3646714..3649035 1 NC_008253.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3649035 feoB 4191346 feoB Escherichia coli 536 ferrous iron transport protein B YP_671372.1 3646714 D 362663 CDS YP_671373.1 110643643 4191347 3649046..3649282 1 NC_008253.1 hypothetical protein 3649282 4191347 ECP_3496 Escherichia coli 536 hypothetical protein YP_671373.1 3649046 D 362663 CDS YP_671374.1 110643644 4191348 3649485..3650378 1 NC_008253.1 hypothetical protein 3650378 4191348 ECP_3497 Escherichia coli 536 hypothetical protein YP_671374.1 3649485 D 362663 CDS YP_671375.1 110643645 4191349 complement(3650598..3651368) 1 NC_008253.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3651368 4191349 ECP_3498 Escherichia coli 536 carboxylesterase BioH YP_671375.1 3650598 R 362663 CDS YP_671376.1 110643646 4191350 3651406..3652089 1 NC_008253.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3652089 4191350 ECP_3499 Escherichia coli 536 gluconate periplasmic binding protein YP_671376.1 3651406 D 362663 CDS YP_671377.1 110643647 4191351 3652148..3652723 1 NC_008253.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3652723 4191351 ECP_3500 Escherichia coli 536 DNA uptake protein YP_671377.1 3652148 D 362663 CDS YP_671378.1 110643648 4191352 3653087..3654403 1 NC_008253.1 high-affinity gluconate transporter 3654403 4191352 ECP_3501 Escherichia coli 536 high-affinity gluconate transporter YP_671378.1 3653087 D 362663 CDS YP_671379.1 110643649 4191353 complement(3654514..3656598) 1 NC_008253.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3656598 malQ 4191353 malQ Escherichia coli 536 4-alpha-glucanotransferase YP_671379.1 3654514 R 362663 CDS YP_671380.1 110643650 4191354 complement(3656608..3659001) 1 NC_008253.1 maltodextrin phosphorylase 3659001 4191354 ECP_3503 Escherichia coli 536 maltodextrin phosphorylase YP_671380.1 3656608 R 362663 CDS YP_671381.1 110643651 4191355 3659624..3662329 1 NC_008253.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3662329 4191355 ECP_3504 Escherichia coli 536 transcriptional regulator MalT YP_671381.1 3659624 D 362663 CDS YP_671382.1 110643652 4191356 complement(3662372..3663388) 1 NC_008253.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3663388 4191356 ECP_3505 Escherichia coli 536 RNA 3'-terminal-phosphate cyclase YP_671382.1 3662372 R 362663 CDS YP_671383.1 110643653 4191357 complement(3663392..3664618) 1 NC_008253.1 protein RtcB 3664618 4191357 ECP_3506 Escherichia coli 536 protein RtcB YP_671383.1 3663392 R 362663 CDS YP_671384.1 110643654 4191358 3664807..3666405 1 NC_008253.1 transcriptional regulatory protein RtcR 3666405 4191358 ECP_3507 Escherichia coli 536 transcriptional regulatory protein RtcR YP_671384.1 3664807 D 362663 CDS YP_671385.1 110643655 4191359 complement(3666387..3667145) 1 NC_008253.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3667145 4191359 ECP_3508 Escherichia coli 536 DNA-binding transcriptional repressor GlpR YP_671385.1 3666387 R 362663 CDS YP_671386.1 110643656 4191360 complement(3667162..3667992) 1 NC_008253.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3667992 4191360 ECP_3509 Escherichia coli 536 intramembrane serine protease GlpG YP_671386.1 3667162 R 362663 CDS YP_671387.1 110643657 4191361 complement(3668037..3668363) 1 NC_008253.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3668363 glpE 4191361 glpE Escherichia coli 536 thiosulfate sulfurtransferase YP_671387.1 3668037 R 362663 CDS YP_671388.1 110643658 4191362 3668553..3670058 1 NC_008253.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3670058 glpD 4191362 glpD Escherichia coli 536 glycerol-3-phosphate dehydrogenase YP_671388.1 3668553 D 362663 CDS YP_671389.1 110643659 4191363 complement(3670112..3670717) 1 NC_008253.1 hypothetical protein 3670717 4191363 ECP_3512 Escherichia coli 536 hypothetical protein YP_671389.1 3670112 R 362663 CDS YP_671390.1 110643660 4191364 complement(3670720..3671496) 1 NC_008253.1 hypothetical protein 3671496 4191364 ECP_3513 Escherichia coli 536 hypothetical protein YP_671390.1 3670720 R 362663 CDS YP_671391.1 110643661 4191385 complement(3671499..3672209) 1 NC_008253.1 hypothetical protein 3672209 4191385 ECP_3514 Escherichia coli 536 hypothetical protein YP_671391.1 3671499 R 362663 CDS YP_671392.1 110643662 4191386 complement(3672383..3673504) 1 NC_008253.1 fimbrial adhesin 3673504 4191386 ECP_3515 Escherichia coli 536 fimbrial adhesin YP_671392.1 3672383 R 362663 CDS YP_671393.1 110643663 4191387 complement(3673519..3674298) 1 NC_008253.1 fimbrial chaperone 3674298 4191387 ECP_3516 Escherichia coli 536 fimbrial chaperone YP_671393.1 3673519 R 362663 CDS YP_671394.1 110643664 4191388 complement(3674264..3674836) 1 NC_008253.1 minor fimbrial subunit 3674836 4191388 ECP_3517 Escherichia coli 536 minor fimbrial subunit YP_671394.1 3674264 R 362663 CDS YP_671395.1 110643665 4191389 complement(3674787..3675350) 1 NC_008253.1 minor fimbrial subunit 3675350 4191389 ECP_3518 Escherichia coli 536 minor fimbrial subunit YP_671395.1 3674787 R 362663 CDS YP_671396.1 110643666 4191390 complement(3675350..3677944) 1 NC_008253.1 outer membrane usher protein 3677944 4191390 ECP_3519 Escherichia coli 536 outer membrane usher protein YP_671396.1 3675350 R 362663 CDS YP_671397.1 110643667 4191391 complement(3677981..3678733) 1 NC_008253.1 fimbrial chaperone protein 3678733 4191391 ECP_3520 Escherichia coli 536 fimbrial chaperone protein YP_671397.1 3677981 R 362663 CDS YP_671398.1 110643668 4191392 complement(3678834..3679538) 1 NC_008253.1 major fimbrial subunit 3679538 4191392 ECP_3521 Escherichia coli 536 major fimbrial subunit YP_671398.1 3678834 R 362663 CDS YP_671399.1 110643669 4191393 complement(3680033..3682480) 1 NC_008253.1 glycogen phosphorylase 3682480 4191393 ECP_3522 Escherichia coli 536 glycogen phosphorylase YP_671399.1 3680033 R 362663 CDS YP_671400.1 110643670 4191394 complement(3682499..3683932) 1 NC_008253.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3683932 glgA 4191394 glgA Escherichia coli 536 glycogen synthase YP_671400.1 3682499 R 362663 CDS YP_671401.1 110643671 4191395 complement(3683932..3685227) 1 NC_008253.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3685227 glgC 4191395 glgC Escherichia coli 536 glucose-1-phosphate adenylyltransferase YP_671401.1 3683932 R 362663 CDS YP_671402.1 110643672 4191396 complement(3685245..3687218) 1 NC_008253.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3687218 4191396 ECP_3525 Escherichia coli 536 glycogen debranching protein YP_671402.1 3685245 R 362663 CDS YP_671403.1 110643673 4191397 complement(3687215..3689401) 1 NC_008253.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3689401 4191397 ECP_3526 Escherichia coli 536 glycogen branching protein YP_671403.1 3687215 R 362663 CDS YP_671404.1 110643674 4191398 complement(3689674..3690777) 1 NC_008253.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3690777 4191398 ECP_3527 Escherichia coli 536 aspartate-semialdehyde dehydrogenase YP_671404.1 3689674 R 362663 CDS YP_671405.1 110643675 4191399 3690969..3691562 1 NC_008253.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3691562 4191399 ECP_3528 Escherichia coli 536 dITP- and XTP- hydrolase YP_671405.1 3690969 D 362663 CDS YP_671406.1 110643676 4191400 complement(3691608..3692903) 1 NC_008253.1 DNA processing protein 3692903 4191400 ECP_3529 Escherichia coli 536 DNA processing protein YP_671406.1 3691608 R 362663 CDS YP_671407.1 110643677 4191401 complement(3692810..3694906) 1 NC_008253.1 DNA helicase 3694906 4191401 ECP_3530 Escherichia coli 536 DNA helicase YP_671407.1 3692810 R 362663 CDS YP_671408.1 110643678 4191402 complement(3695047..3696387) 1 NC_008253.1 low affinity gluconate transporter 3696387 4191402 ECP_3531 Escherichia coli 536 low affinity gluconate transporter YP_671408.1 3695047 R 362663 CDS YP_671409.1 110643679 4191403 complement(3696391..3696879) 1 NC_008253.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3696879 gntK 4191403 gntK Escherichia coli 536 gluconate kinase YP_671409.1 3696391 R 362663 CDS YP_671410.1 110643680 4191404 complement(3697057..3698052) 1 NC_008253.1 GalR/LacI family gluconate utilization operon gntUKR repressor 3698052 4191404 ECP_3533 Escherichia coli 536 GalR/LacI family gluconate utilization operon gntUKR repressor YP_671410.1 3697057 R 362663 CDS YP_671411.1 110643681 4189489 complement(3698145..3698840) 1 NC_008253.1 pirin-related protein 3698840 4189489 ECP_3534 Escherichia coli 536 pirin-related protein YP_671411.1 3698145 R 362663 CDS YP_671412.1 110643682 4189490 complement(3698963..3700000) 1 NC_008253.1 dehydrogenase 3700000 4189490 ECP_3535 Escherichia coli 536 dehydrogenase YP_671412.1 3698963 R 362663 CDS YP_671413.1 110643683 4189491 3700334..3700822 1 NC_008253.1 YhhY; regulated by the fur regulator; unknown function; acetyltransferase YhhY 3700822 4189491 ECP_3536 Escherichia coli 536 acetyltransferase YhhY YP_671413.1 3700334 D 362663 CDS YP_671414.1 110643684 4189492 3701058..3702242 1 NC_008253.1 hypothetical protein 3702242 4189492 ECP_3537 Escherichia coli 536 hypothetical protein YP_671414.1 3701058 D 362663 CDS YP_671415.1 110643685 4189493 3702271..3702726 1 NC_008253.1 hypothetical protein 3702726 4189493 ECP_3538 Escherichia coli 536 hypothetical protein YP_671415.1 3702271 D 362663 CDS YP_671416.1 110643686 4189494 3703176..3703460 1 NC_008253.1 hypothetical protein 3703460 4189494 ECP_3539 Escherichia coli 536 hypothetical protein YP_671416.1 3703176 D 362663 CDS YP_671417.1 110643687 4189495 complement(3703498..3705231) 1 NC_008253.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3705231 ggt 4189495 ggt Escherichia coli 536 gamma-glutamyltranspeptidase YP_671417.1 3703498 R 362663 CDS YP_671418.1 110643688 4189496 3705351..3705791 1 NC_008253.1 hypothetical protein 3705791 4189496 ECP_3541 Escherichia coli 536 hypothetical protein YP_671418.1 3705351 D 362663 CDS YP_671419.1 110643689 4189497 complement(3705778..3706521) 1 NC_008253.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3706521 ugpQ 4189497 ugpQ Escherichia coli 536 glycerophosphodiester phosphodiesterase YP_671419.1 3705778 R 362663 CDS YP_671420.1 110643690 4189498 complement(3706518..3707588) 1 NC_008253.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3707588 ugpC 4189498 ugpC Escherichia coli 536 glycerol-3-phosphate transporter ATP-binding subunit YP_671420.1 3706518 R 362663 CDS YP_671421.1 110643691 4189499 complement(3707590..3708435) 1 NC_008253.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3708435 4189499 ECP_3544 Escherichia coli 536 glycerol-3-phosphate transporter membrane protein YP_671421.1 3707590 R 362663 CDS YP_671422.1 110643692 4189500 complement(3708432..3709319) 1 NC_008253.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3709319 4189500 ECP_3545 Escherichia coli 536 glycerol-3-phosphate transporter permease YP_671422.1 3708432 R 362663 CDS YP_671423.1 110643693 4189501 complement(3709417..3710733) 1 NC_008253.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3710733 4189501 ECP_3546 Escherichia coli 536 glycerol-3-phosphate transporter periplasmic binding protein YP_671423.1 3709417 R 362663 CDS YP_671424.1 110643694 4189502 complement(3711130..3711843) 1 NC_008253.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3711843 livF 4189502 livF Escherichia coli 536 leucine/isoleucine/valine transporter ATP-binding subunit YP_671424.1 3711130 R 362663 CDS YP_671425.1 110643695 4189503 complement(3711845..3712612) 1 NC_008253.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3712612 livG 4189503 livG Escherichia coli 536 leucine/isoleucine/valine transporter ATP-binding subunit YP_671425.1 3711845 R 362663 CDS YP_671426.1 110643696 4189504 complement(3712609..3713886) 1 NC_008253.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3713886 livM 4189504 livM Escherichia coli 536 leucine/isoleucine/valine transporter permease subunit YP_671426.1 3712609 R 362663 CDS YP_671427.1 110643697 4189505 complement(3713883..3714809) 1 NC_008253.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3714809 4189505 ECP_3550 Escherichia coli 536 branched-chain amino acid transporter permease subunit LivH YP_671427.1 3713883 R 362663 CDS YP_671428.1 110643698 4189506 complement(3714857..3715966) 1 NC_008253.1 leucine-specific binding protein 3715966 4189506 ECP_3551 Escherichia coli 536 leucine-specific binding protein YP_671428.1 3714857 R 362663 CDS YP_671429.1 110643699 4189507 3716390..3716773 1 NC_008253.1 hypothetical protein 3716773 4189507 ECP_3552 Escherichia coli 536 hypothetical protein YP_671429.1 3716390 D 362663 CDS YP_671430.1 110643700 4189162 complement(3716961..3718064) 1 NC_008253.1 Leu/Ile/Val-binding protein precursor 3718064 4189162 ECP_3553 Escherichia coli 536 Leu/Ile/Val-binding protein precursor YP_671430.1 3716961 R 362663 CDS YP_671431.1 110643701 4189163 complement(3718335..3719189) 1 NC_008253.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3719189 4189163 ECP_3554 Escherichia coli 536 RNA polymerase factor sigma-32 YP_671431.1 3718335 R 362663 CDS YP_671432.1 110643702 4189164 complement(3719434..3720492) 1 NC_008253.1 ABC transporter membrane protein; cell division protein FtsX 3720492 ftsX 4189164 ftsX Escherichia coli 536 cell division protein FtsX YP_671432.1 3719434 R 362663 CDS YP_671433.1 110643703 4189165 complement(3720485..3721153) 1 NC_008253.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3721153 4189165 ECP_3556 Escherichia coli 536 cell division protein FtsE YP_671433.1 3720485 R 362663 CDS YP_671434.1 110643704 4189166 complement(3721156..3722652) 1 NC_008253.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3722652 4189166 ECP_3557 Escherichia coli 536 cell division protein FtsY YP_671434.1 3721156 R 362663 CDS YP_671435.1 110643705 4189167 3722802..3723398 1 NC_008253.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3723398 rsmD 4189167 rsmD Escherichia coli 536 16S rRNA m(2)G966-methyltransferase YP_671435.1 3722802 D 362663 CDS YP_671436.1 110643706 4189168 3723388..3723657 1 NC_008253.1 hypothetical protein 3723657 4189168 ECP_3559 Escherichia coli 536 hypothetical protein YP_671436.1 3723388 D 362663 CDS YP_671437.1 110643707 4189169 complement(3723660..3724019) 1 NC_008253.1 hypothetical protein 3724019 4189169 ECP_3560 Escherichia coli 536 hypothetical protein YP_671437.1 3723660 R 362663 CDS YP_671438.1 110643708 4189170 3724160..3724786 1 NC_008253.1 hypothetical protein 3724786 4189170 ECP_3561 Escherichia coli 536 hypothetical protein YP_671438.1 3724160 D 362663 CDS YP_671439.1 110643709 4189171 3724860..3727058 1 NC_008253.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3727058 zntA 4189171 zntA Escherichia coli 536 zinc/cadmium/mercury/lead-transporting ATPase YP_671439.1 3724860 D 362663 CDS YP_671440.1 110643710 4189172 complement(3727236..3727958) 1 NC_008253.1 transposase 3727958 4189172 ECP_3563 Escherichia coli 536 transposase YP_671440.1 3727236 R 362663 CDS YP_671441.1 110643711 4189173 complement(3728063..3728584) 1 NC_008253.1 IS transposase 3728584 4189173 ECP_3564 Escherichia coli 536 IS transposase YP_671441.1 3728063 R 362663 CDS YP_671442.1 110643712 4189174 complement(3728763..3729008) 1 NC_008253.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3729008 4189174 ECP_3565 Escherichia coli 536 sulfur transfer protein SirA YP_671442.1 3728763 R 362663 CDS YP_671443.1 110643713 4189175 3729229..3729894 1 NC_008253.1 hypothetical protein 3729894 4189175 ECP_3566 Escherichia coli 536 hypothetical protein YP_671443.1 3729229 D 362663 CDS YP_671444.1 110643714 4189176 3729967..3730524 1 NC_008253.1 hypothetical protein 3730524 4189176 ECP_3567 Escherichia coli 536 hypothetical protein YP_671444.1 3729967 D 362663 CDS YP_671445.1 110643715 4189177 complement(3730528..3731745) 1 NC_008253.1 major facilitator superfamily transporter 3731745 4189177 ECP_3568 Escherichia coli 536 major facilitator superfamily transporter YP_671445.1 3730528 R 362663 CDS YP_671446.1 110643716 4189178 3731877..3732926 1 NC_008253.1 hypothetical protein 3732926 4189178 ECP_3569 Escherichia coli 536 hypothetical protein YP_671446.1 3731877 D 362663 CDS YP_671447.1 110643717 4189179 3732981..3733568 1 NC_008253.1 holo-(acyl carrier protein) synthase 2 3733568 4189179 ECP_3570 Escherichia coli 536 holo-(acyl carrier protein) synthase 2 YP_671447.1 3732981 D 362663 CDS YP_671448.1 110643718 4189180 3733679..3735253 1 NC_008253.1 nickel-binding periplasmic protein 3735253 4189180 ECP_3571 Escherichia coli 536 nickel-binding periplasmic protein YP_671448.1 3733679 D 362663 CDS YP_671449.1 110643719 4189181 3735253..3736197 1 NC_008253.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3736197 4189181 ECP_3572 Escherichia coli 536 nickel transporter permease NikB YP_671449.1 3735253 D 362663 CDS YP_671450.1 110643720 4187509 3736194..3737027 1 NC_008253.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3737027 nikC 4187509 nikC Escherichia coli 536 nickel transporter permease NikC YP_671450.1 3736194 D 362663 CDS YP_671451.1 110643721 4187510 3737027..3737791 1 NC_008253.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3737791 nikD 4187510 nikD Escherichia coli 536 nickel transporter ATP-binding protein NikD YP_671451.1 3737027 D 362663 CDS YP_671452.1 110643722 4187511 3737788..3738594 1 NC_008253.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3738594 nikE 4187511 nikE Escherichia coli 536 nickel transporter ATP-binding protein NikE YP_671452.1 3737788 D 362663 CDS YP_671453.1 110643723 4187512 3738600..3739001 1 NC_008253.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3739001 4187512 ECP_3576 Escherichia coli 536 nickel responsive regulator YP_671453.1 3738600 D 362663 CDS YP_671454.1 110643724 4187513 complement(3739010..3740134) 1 NC_008253.1 hypothetical protein 3740134 4187513 ECP_3577 Escherichia coli 536 hypothetical protein YP_671454.1 3739010 R 362663 CDS YP_671455.1 110643725 4187514 complement(3740134..3742869) 1 NC_008253.1 ABC transporter ATP-binding protein 3742869 4187514 ECP_3578 Escherichia coli 536 ABC transporter ATP-binding protein YP_671455.1 3740134 R 362663 CDS YP_671456.1 110643726 4187515 complement(3742866..3743933) 1 NC_008253.1 hypothetical protein 3743933 4187515 ECP_3579 Escherichia coli 536 hypothetical protein YP_671456.1 3742866 R 362663 CDS YP_671457.1 110643727 4187516 3744209..3744415 1 NC_008253.1 hypothetical protein 3744415 4187516 ECP_3580 Escherichia coli 536 hypothetical protein YP_671457.1 3744209 D 362663 CDS YP_671458.1 110643728 4187517 3744667..3745719 1 NC_008253.1 hypothetical protein 3745719 4187517 ECP_3581 Escherichia coli 536 hypothetical protein YP_671458.1 3744667 D 362663 CDS YP_671459.1 110643729 4187518 complement(3745806..3746999) 1 NC_008253.1 hypothetical protein 3746999 4187518 ECP_3582 Escherichia coli 536 hypothetical protein YP_671459.1 3745806 R 362663 CDS YP_671460.1 110643730 4187519 3747231..3748730 1 NC_008253.1 low-affinity inorganic phosphate transporter 1 3748730 4187519 ECP_3583 Escherichia coli 536 low-affinity inorganic phosphate transporter 1 YP_671460.1 3747231 D 362663 CDS YP_671461.1 110643731 4187520 complement(3748801..3749136) 1 NC_008253.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3749136 4187520 ECP_3584 Escherichia coli 536 universal stress protein UspB YP_671461.1 3748801 R 362663 CDS YP_671462.1 110643732 4187521 3749527..3749961 1 NC_008253.1 universal stress protein 3749961 4187521 ECP_3585 Escherichia coli 536 universal stress protein YP_671462.1 3749527 D 362663 CDS YP_671463.1 110643733 4187522 3750278..3751747 1 NC_008253.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3751747 4187522 ECP_3586 Escherichia coli 536 inner membrane transporter YhiP YP_671463.1 3750278 D 362663 CDS YP_671464.1 110643734 4187523 complement(3751796..3752590) 1 NC_008253.1 predicted SAM-dependent methyltransferase; methyltransferase 3752590 4187523 ECP_3587 Escherichia coli 536 methyltransferase YP_671464.1 3751796 R 362663 CDS YP_671465.1 110643735 4187524 complement(3752556..3754598) 1 NC_008253.1 oligopeptidase A 3754598 4187524 ECP_3588 Escherichia coli 536 oligopeptidase A YP_671465.1 3752556 R 362663 CDS YP_671466.1 110643736 4187525 3754801..3755643 1 NC_008253.1 hypothetical protein 3755643 4187525 ECP_3589 Escherichia coli 536 hypothetical protein YP_671466.1 3754801 D 362663 CDS YP_671467.1 110643737 4187526 3755715..3757067 1 NC_008253.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3757067 4187526 ECP_3590 Escherichia coli 536 glutathione reductase YP_671467.1 3755715 D 362663 CDS YP_671468.1 110643738 4187527 3757232..3757405 1 NC_008253.1 hypothetical protein 3757405 4187527 ECP_3591 Escherichia coli 536 hypothetical protein YP_671468.1 3757232 D 362663 CDS YP_671469.1 110643739 4191150 3757738..3758163 1 NC_008253.1 arsenate reductase 3758163 4191150 ECP_3592 Escherichia coli 536 arsenate reductase YP_671469.1 3757738 D 362663 CDS YP_671470.1 110643740 4191151 3758780..3758953 1 NC_008253.1 hypothetical protein 3758953 4191151 ECP_3593 Escherichia coli 536 hypothetical protein YP_671470.1 3758780 D 362663 CDS YP_671471.1 110643741 4191152 3759347..3759913 1 NC_008253.1 outer membrane protein Slp 3759913 4191152 ECP_3594 Escherichia coli 536 outer membrane protein Slp YP_671471.1 3759347 D 362663 CDS YP_671472.1 110643742 4191153 3760066..3760596 1 NC_008253.1 transcriptional regulator YhiF 3760596 4191153 ECP_3595 Escherichia coli 536 transcriptional regulator YhiF YP_671472.1 3760066 D 362663 CDS YP_671473.1 110643743 4191154 complement(3760653..3761681) 1 NC_008253.1 heme/hemoglobin transport protein 3761681 4191154 ECP_3596 Escherichia coli 536 heme/hemoglobin transport protein YP_671473.1 3760653 R 362663 CDS YP_671474.1 110643744 4191155 complement(3761730..3763712) 1 NC_008253.1 outer membrane hemin receptor 3763712 4191155 ECP_3597 Escherichia coli 536 outer membrane hemin receptor YP_671474.1 3761730 R 362663 CDS YP_671475.1 110643745 4191156 complement(3763813..3763974) 1 NC_008253.1 hypothetical protein 3763974 4191156 ECP_3598 Escherichia coli 536 hypothetical protein YP_671475.1 3763813 R 362663 CDS YP_671476.1 110643746 4191157 complement(3764124..3764288) 1 NC_008253.1 hypothetical protein 3764288 4191157 ECP_3599 Escherichia coli 536 hypothetical protein YP_671476.1 3764124 R 362663 CDS YP_671477.1 110643747 4191158 3764396..3765310 1 NC_008253.1 hemin binding protein 3765310 4191158 ECP_3600 Escherichia coli 536 hemin binding protein YP_671477.1 3764396 D 362663 CDS YP_671478.1 110643748 4191159 3765330..3766667 1 NC_008253.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3766667 4191159 ECP_3601 Escherichia coli 536 coproporphyrinogen III oxidase YP_671478.1 3765330 D 362663 CDS YP_671479.1 110643749 4191160 3766680..3767174 1 NC_008253.1 hypothetical protein 3767174 4191160 ECP_3602 Escherichia coli 536 hypothetical protein YP_671479.1 3766680 D 362663 CDS YP_671480.1 110643750 4191161 3767174..3767797 1 NC_008253.1 hypothetical protein 3767797 4191161 ECP_3603 Escherichia coli 536 hypothetical protein YP_671480.1 3767174 D 362663 CDS YP_671481.1 110643751 4191162 3767882..3768838 1 NC_008253.1 permease of iron compound ABC transport system 3768838 4191162 ECP_3604 Escherichia coli 536 permease of iron compound ABC transport system YP_671481.1 3767882 D 362663 CDS YP_671482.1 110643752 4191163 3768835..3769605 1 NC_008253.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 3769605 hmuV 4191163 hmuV Escherichia coli 536 hemin importer ATP-binding subunit YP_671482.1 3768835 D 362663 CDS YP_671483.1 110643753 4191164 complement(3769657..3770304) 1 NC_008253.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 3770304 4191164 ECP_3606 Escherichia coli 536 Mg(2+) transport ATPase YP_671483.1 3769657 R 362663 CDS YP_671484.1 110643754 4191165 complement(3770368..3770694) 1 NC_008253.1 acid-resistance protein 3770694 hdeB 4191165 hdeB Escherichia coli 536 acid-resistance protein YP_671484.1 3770368 R 362663 CDS YP_671485.1 110643755 4191166 complement(3770810..3771142) 1 NC_008253.1 inactive form; acid-resistance protein 3771142 4191166 ECP_3608 Escherichia coli 536 acid-resistance protein YP_671485.1 3770810 R 362663 CDS YP_671486.1 110643756 4191167 3771397..3771969 1 NC_008253.1 acid-resistance membrane protein 3771969 4191167 ECP_3609 Escherichia coli 536 acid-resistance membrane protein YP_671486.1 3771397 D 362663 CDS YP_671487.1 110643757 4191168 3772736..3773296 1 NC_008253.1 hypothetical protein 3773296 4191168 ECP_3610 Escherichia coli 536 hypothetical protein YP_671487.1 3772736 D 362663 CDS YP_671488.1 110643758 4191169 3773346..3773633 1 NC_008253.1 hypothetical protein 3773633 4191169 ECP_3611 Escherichia coli 536 hypothetical protein YP_671488.1 3773346 D 362663 CDS YP_671489.1 110643759 4191248 3773635..3774792 1 NC_008253.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3774792 4191248 ECP_3612 Escherichia coli 536 multidrug efflux system protein MdtE YP_671489.1 3773635 D 362663 CDS YP_671490.1 110643760 4191249 3774817..3777930 1 NC_008253.1 hypothetical protein 3777930 4191249 ECP_3613 Escherichia coli 536 hypothetical protein YP_671490.1 3774817 D 362663 CDS YP_671491.1 110643761 4191250 complement(3778293..3779021) 1 NC_008253.1 transcriptional regulator YhiW 3779021 4191250 ECP_3614 Escherichia coli 536 transcriptional regulator YhiW YP_671491.1 3778293 R 362663 CDS YP_671492.1 110643762 4191251 complement(3779390..3780214) 1 NC_008253.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3780214 4191251 ECP_3615 Escherichia coli 536 DNA-binding transcriptional regulator GadX YP_671492.1 3779390 R 362663 CDS YP_671493.1 110643763 4191252 complement(3780582..3781982) 1 NC_008253.1 glutamate decarboxylase 3781982 4191252 ECP_3616 Escherichia coli 536 glutamate decarboxylase YP_671493.1 3780582 R 362663 CDS YP_671494.1 110643764 4191253 complement(3782193..3782489) 1 NC_008253.1 similar to the C-terminal part of the probable cytochrome C peroxidase YhjA; hypothetical protein 3782489 4191253 ECP_3617 Escherichia coli 536 hypothetical protein YP_671494.1 3782193 R 362663 CDS YP_671495.1 110643765 4191254 complement(3782585..3783589) 1 NC_008253.1 similar to the N-terminal part of the probable cytochrome C peroxidase YhjA; hypothetical protein 3783589 4191254 ECP_3618 Escherichia coli 536 hypothetical protein YP_671495.1 3782585 R 362663 CDS YP_671496.1 110643766 4191255 3783994..3785643 1 NC_008253.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3785643 treF 4191255 treF Escherichia coli 536 trehalase YP_671496.1 3783994 D 362663 CDS YP_671497.1 110643767 4191256 complement(3785694..3786296) 1 NC_008253.1 transcriptional regulator YhjB 3786296 4191256 ECP_3620 Escherichia coli 536 transcriptional regulator YhjB YP_671497.1 3785694 R 362663 CDS YP_671498.1 110643768 4191257 3786744..3787664 1 NC_008253.1 transcriptional regulator YhjC 3787664 4191257 ECP_3621 Escherichia coli 536 transcriptional regulator YhjC YP_671498.1 3786744 D 362663 CDS YP_671499.1 110643769 4191258 3787763..3788776 1 NC_008253.1 tRNA-processing ribonuclease 3788776 4191258 ECP_3622 Escherichia coli 536 tRNA-processing ribonuclease YP_671499.1 3787763 D 362663 CDS YP_671500.1 110643770 4191259 3789169..3790491 1 NC_008253.1 metabolite transport protein YhjE 3790491 4191259 ECP_3623 Escherichia coli 536 metabolite transport protein YhjE YP_671500.1 3789169 D 362663 CDS YP_671501.1 110643771 4191260 complement(3790670..3792745) 1 NC_008253.1 AsmA family protein 3792745 4191260 ECP_3624 Escherichia coli 536 AsmA family protein YP_671501.1 3790670 R 362663 CDS YP_671502.1 110643772 4191261 complement(3792800..3793567) 1 NC_008253.1 in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase 3793567 4191261 ECP_3625 Escherichia coli 536 diguanylate phosphodiesterase YP_671502.1 3792800 R 362663 CDS YP_671503.1 110643773 4191262 3793799..3794728 1 NC_008253.1 2-dehydro-3-deoxygluconokinase 3794728 4191262 ECP_3626 Escherichia coli 536 2-dehydro-3-deoxygluconokinase YP_671503.1 3793799 D 362663 CDS YP_671504.1 110643774 4191263 complement(3794824..3796320) 1 NC_008253.1 protein YhjJ 3796320 4191263 ECP_3627 Escherichia coli 536 protein YhjJ YP_671504.1 3794824 R 362663 CDS YP_671505.1 110643775 4191264 complement(3796540..3797826) 1 NC_008253.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3797826 4191264 ECP_3628 Escherichia coli 536 C4-dicarboxylate transporter DctA YP_671505.1 3796540 R 362663 CDS YP_671506.2 229560209 4191265 complement(3798009..3799964) 1 NC_008253.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli; phosphodiesterase 3799964 4191265 ECP_3629 Escherichia coli 536 phosphodiesterase YP_671506.2 3798009 R 362663 CDS YP_671507.1 110643777 4191266 complement(3800079..3803552) 1 NC_008253.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3803552 4191266 ECP_3630 Escherichia coli 536 cellulose synthase subunit BcsC YP_671507.1 3800079 R 362663 CDS YP_671508.1 110643778 4191500 complement(3803534..3804640) 1 NC_008253.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3804640 4191500 ECP_3631 Escherichia coli 536 endo-1,4-D-glucanase YP_671508.1 3803534 R 362663 CDS YP_671509.1 110643779 4191501 complement(3804647..3806986) 1 NC_008253.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3806986 4191501 ECP_3632 Escherichia coli 536 cellulose synthase regulator protein YP_671509.1 3804647 R 362663 CDS YP_671510.1 110643780 4191502 complement(3806997..3809615) 1 NC_008253.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3809615 bcsA 4191502 bcsA Escherichia coli 536 cellulose synthase catalytic subunit YP_671510.1 3806997 R 362663 CDS YP_671511.1 110643781 4191503 complement(3809612..3810364) 1 NC_008253.1 cell division protein 3810364 4191503 ECP_3634 Escherichia coli 536 cell division protein YP_671511.1 3809612 R 362663 CDS YP_671512.1 110643782 4191504 complement(3810376..3810564) 1 NC_008253.1 hypothetical protein 3810564 4191504 ECP_3635 Escherichia coli 536 hypothetical protein YP_671512.1 3810376 R 362663 CDS YP_671513.1 110643783 4191505 3810849..3812408 1 NC_008253.1 hypothetical protein 3812408 4191505 ECP_3636 Escherichia coli 536 hypothetical protein YP_671513.1 3810849 D 362663 CDS YP_671514.1 110643784 4191506 3812405..3812596 1 NC_008253.1 hypothetical protein 3812596 4191506 ECP_3637 Escherichia coli 536 hypothetical protein YP_671514.1 3812405 D 362663 CDS YP_671515.1 110643785 4191507 3812593..3814272 1 NC_008253.1 hypothetical protein 3814272 4191507 ECP_3638 Escherichia coli 536 hypothetical protein YP_671515.1 3812593 D 362663 CDS YP_671516.1 110643786 4191508 complement(3814359..3814634) 1 NC_008253.1 hypothetical protein 3814634 4191508 ECP_3639 Escherichia coli 536 hypothetical protein YP_671516.1 3814359 R 362663 CDS YP_671517.1 110643787 4191509 3814942..3816213 1 NC_008253.1 transporter 3816213 4191509 ECP_3640 Escherichia coli 536 transporter YP_671517.1 3814942 D 362663 CDS YP_671518.1 110643788 4191510 complement(3816243..3817247) 1 NC_008253.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 3817247 dppF 4191510 dppF Escherichia coli 536 dipeptide transporter ATP-binding subunit YP_671518.1 3816243 R 362663 CDS YP_671519.1 110643789 4191511 complement(3817244..3818227) 1 NC_008253.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 3818227 dppD 4191511 dppD Escherichia coli 536 dipeptide transporter ATP-binding subunit YP_671519.1 3817244 R 362663 CDS YP_671520.1 110643790 4191512 complement(3818238..3819140) 1 NC_008253.1 dipeptide transporter 3819140 4191512 ECP_3643 Escherichia coli 536 dipeptide transporter YP_671520.1 3818238 R 362663 CDS YP_671521.1 110643791 4191513 complement(3819150..3820169) 1 NC_008253.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 3820169 4191513 ECP_3644 Escherichia coli 536 dipeptide transporter permease DppB YP_671521.1 3819150 R 362663 CDS YP_671523.1 110643793 4191515 complement(3820476..3822083) 1 NC_008253.1 periplasmic dipeptide transport protein 3822083 4191515 ECP_3646 Escherichia coli 536 periplasmic dipeptide transport protein YP_671523.1 3820476 R 362663 CDS YP_671525.1 110643795 4191517 complement(3823012..3824703) 1 NC_008253.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 3824703 4191517 ECP_3648 Escherichia coli 536 phosphoethanolamine transferase YP_671525.1 3823012 R 362663 CDS YP_671526.1 110643796 4191518 complement(3825027..3826235) 1 NC_008253.1 hypothetical protein 3826235 4191518 ECP_3649 Escherichia coli 536 hypothetical protein YP_671526.1 3825027 R 362663 CDS YP_671527.1 110643797 4191519 complement(3826464..3827162) 1 NC_008253.1 hypothetical protein 3827162 4191519 ECP_3650 Escherichia coli 536 hypothetical protein YP_671527.1 3826464 R 362663 CDS YP_671528.1 110643798 4188718 3827880..3828320 1 NC_008253.1 hypothetical protein 3828320 4188718 ECP_3653 Escherichia coli 536 hypothetical protein YP_671528.1 3827880 D 362663 CDS YP_671529.1 110643799 4188719 complement(3828289..3830622) 1 NC_008253.1 biotin sulfoxide reductase 3830622 4188719 ECP_3654 Escherichia coli 536 biotin sulfoxide reductase YP_671529.1 3828289 R 362663 CDS YP_671530.1 110643800 4188720 3830775..3831434 1 NC_008253.1 outer membrane lipoprotein 3831434 4188720 ECP_3655 Escherichia coli 536 outer membrane lipoprotein YP_671530.1 3830775 D 362663 CDS YP_671531.1 110643801 4188721 3831538..3832512 1 NC_008253.1 2-ketogluconate reductase 3832512 4188721 ECP_3656 Escherichia coli 536 2-ketogluconate reductase YP_671531.1 3831538 D 362663 CDS YP_671532.1 110643802 4188722 complement(3832562..3833272) 1 NC_008253.1 hypothetical protein 3833272 4188722 ECP_3657 Escherichia coli 536 hypothetical protein YP_671532.1 3832562 R 362663 CDS YP_671533.1 110643803 4188723 3833706..3833996 1 NC_008253.1 transcriptional regulator 3833996 4188723 ECP_3658 Escherichia coli 536 transcriptional regulator YP_671533.1 3833706 D 362663 CDS YP_671534.1 110643804 4188724 3834277..3834489 1 NC_008253.1 major cold shock protein 3834489 4188724 ECP_3659 Escherichia coli 536 major cold shock protein YP_671534.1 3834277 D 362663 CDS YP_671535.1 110643805 4188725 complement(3834677..3834889) 1 NC_008253.1 small toxic polypeptide 3834889 4188725 ECP_3660 Escherichia coli 536 small toxic polypeptide YP_671535.1 3834677 R 362663 CDS YP_671536.1 110643806 4188726 complement(3835152..3837221) 1 NC_008253.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 3837221 glyS 4188726 glyS Escherichia coli 536 glycyl-tRNA synthetase subunit beta YP_671536.1 3835152 R 362663 CDS YP_671537.1 110643807 4188727 complement(3837231..3838142) 1 NC_008253.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3838142 glyQ 4188727 glyQ Escherichia coli 536 glycyl-tRNA synthetase subunit alpha YP_671537.1 3837231 R 362663 CDS YP_671538.1 110643808 4188728 complement(3838237..3838518) 1 NC_008253.1 hypothetical protein 3838518 4188728 ECP_3663 Escherichia coli 536 hypothetical protein YP_671538.1 3838237 R 362663 CDS YP_671539.1 110643809 4188729 3838771..3839715 1 NC_008253.1 hypothetical protein 3839715 4188729 ECP_3664 Escherichia coli 536 hypothetical protein YP_671539.1 3838771 D 362663 CDS YP_671540.1 110643810 4188730 complement(3839756..3840193) 1 NC_008253.1 hypothetical protein 3840193 4188730 ECP_3665 Escherichia coli 536 hypothetical protein YP_671540.1 3839756 R 362663 CDS YP_671541.1 110643811 4188731 complement(3840239..3840580) 1 NC_008253.1 hypothetical protein 3840580 4188731 ECP_3666 Escherichia coli 536 hypothetical protein YP_671541.1 3840239 R 362663 CDS YP_671542.1 110643812 4188732 complement(3840749..3842203) 1 NC_008253.1 xylulokinase 3842203 4188732 ECP_3667 Escherichia coli 536 xylulokinase YP_671542.1 3840749 R 362663 CDS YP_671543.1 110643813 4188059 complement(3842275..3843597) 1 NC_008253.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 3843597 4188059 ECP_3668 Escherichia coli 536 xylose isomerase YP_671543.1 3842275 R 362663 CDS YP_671544.1 110643814 4188060 3843963..3844955 1 NC_008253.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3844955 xylF 4188060 xylF Escherichia coli 536 D-xylose transporter subunit XylF YP_671544.1 3843963 D 362663 CDS YP_671545.2 229560208 4188061 3845033..3846574 1 NC_008253.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3846574 4188061 ECP_3670 Escherichia coli 536 xylose transporter ATP-binding subunit YP_671545.2 3845033 D 362663 CDS YP_671546.1 110643816 4188062 3846552..3847733 1 NC_008253.1 xylose transport system permease XylH 3847733 4188062 ECP_3671 Escherichia coli 536 xylose transport system permease XylH YP_671546.1 3846552 D 362663 CDS YP_671547.1 110643817 4188063 3847811..3848989 1 NC_008253.1 xylose operon regulatory protein 3848989 4188063 ECP_3672 Escherichia coli 536 xylose operon regulatory protein YP_671547.1 3847811 D 362663 CDS YP_671548.1 110643818 4188064 complement(3849097..3849921) 1 NC_008253.1 hypothetical protein 3849921 4188064 ECP_3673 Escherichia coli 536 hypothetical protein YP_671548.1 3849097 R 362663 CDS YP_671549.1 110643819 4188065 3850071..3850244 1 NC_008253.1 hypothetical protein 3850244 4188065 ECP_3674 Escherichia coli 536 hypothetical protein YP_671549.1 3850071 D 362663 CDS YP_671550.1 110643820 4188066 3850241..3852271 1 NC_008253.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3852271 malS 4188066 malS Escherichia coli 536 periplasmic alpha-amylase YP_671550.1 3850241 D 362663 CDS YP_671551.1 110643821 4188067 3852449..3853702 1 NC_008253.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3853702 avtA 4188067 avtA Escherichia coli 536 valine--pyruvate transaminase YP_671551.1 3852449 D 362663 CDS YP_671552.1 110643822 4188068 complement(3853854..3854327) 1 NC_008253.1 electron transport protein YsaA 3854327 4188068 ECP_3677 Escherichia coli 536 electron transport protein YsaA YP_671552.1 3853854 R 362663 CDS YP_671553.1 110643823 4188069 complement(3854429..3855277) 1 NC_008253.1 transcriptional regulator YiaJ 3855277 4188069 ECP_3678 Escherichia coli 536 transcriptional regulator YiaJ YP_671553.1 3854429 R 362663 CDS YP_671554.1 110643824 4188070 3855478..3856476 1 NC_008253.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3856476 4188070 ECP_3679 Escherichia coli 536 2,3-diketo-L-gulonate reductase YP_671554.1 3855478 D 362663 CDS YP_671555.1 110643825 4188071 3856488..3856952 1 NC_008253.1 hypothetical protein 3856952 4188071 ECP_3680 Escherichia coli 536 hypothetical protein YP_671555.1 3856488 D 362663 CDS YP_671556.1 110643826 4188072 3856975..3857895 1 NC_008253.1 hypothetical protein 3857895 4188072 ECP_3681 Escherichia coli 536 hypothetical protein YP_671556.1 3856975 D 362663 CDS YP_671557.1 110643827 4188073 3858009..3858476 1 NC_008253.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 3858476 4188073 ECP_3682 Escherichia coli 536 2,3-diketo-L-gulonate TRAP transporter small permease YiaM YP_671557.1 3858009 D 362663 CDS YP_671558.1 110643828 4188074 3858479..3859756 1 NC_008253.1 DedA family, membrane protein YiaN 3859756 4188074 ECP_3683 Escherichia coli 536 DedA family, membrane protein YiaN YP_671558.1 3858479 D 362663 CDS YP_671559.1 110643829 4188075 3859769..3860755 1 NC_008253.1 extracellular solute-binding protein YiaO 3860755 4188075 ECP_3684 Escherichia coli 536 extracellular solute-binding protein YiaO YP_671559.1 3859769 D 362663 CDS YP_671560.1 110643830 4188076 3860759..3862255 1 NC_008253.1 cryptic L-xylulose kinase 3862255 4188076 ECP_3685 Escherichia coli 536 cryptic L-xylulose kinase YP_671560.1 3860759 D 362663 CDS YP_671561.1 110643831 4188077 3862252..3862914 1 NC_008253.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3862914 sgbH 4188077 sgbH Escherichia coli 536 3-keto-L-gulonate-6-phosphate decarboxylase YP_671561.1 3862252 D 362663 CDS YP_671562.1 110643832 4190857 3862907..3863767 1 NC_008253.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 3863767 4190857 ECP_3687 Escherichia coli 536 L-xylulose 5-phosphate 3-epimerase YP_671562.1 3862907 D 362663 CDS YP_671563.1 110643833 4190858 3863761..3864456 1 NC_008253.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3864456 sgbE 4190858 sgbE Escherichia coli 536 L-ribulose-5-phosphate 4-epimerase YP_671563.1 3863761 D 362663 CDS YP_671564.1 110643834 4190861 complement(3866208..3867359) 1 NC_008253.1 alcohol dehydrogenase 3867359 4190861 ECP_3691 Escherichia coli 536 alcohol dehydrogenase YP_671564.1 3866208 R 362663 CDS YP_671565.1 110643835 4190862 complement(3867550..3869394) 1 NC_008253.1 selenocysteinyl-tRNA-specific translation factor 3869394 4190862 ECP_3692 Escherichia coli 536 selenocysteinyl-tRNA-specific translation factor YP_671565.1 3867550 R 362663 CDS YP_671566.1 110643836 4190863 complement(3869391..3870782) 1 NC_008253.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 3870782 4190863 ECP_3693 Escherichia coli 536 selenocysteine synthase YP_671566.1 3869391 R 362663 CDS YP_671567.1 110643837 4190864 complement(3870880..3871488) 1 NC_008253.1 glutathione S-transferase 3871488 4190864 ECP_3694 Escherichia coli 536 glutathione S-transferase YP_671567.1 3870880 R 362663 CDS YP_671568.1 110643838 4190865 complement(3871559..3872695) 1 NC_008253.1 hypothetical protein 3872695 4190865 ECP_3695 Escherichia coli 536 hypothetical protein YP_671568.1 3871559 R 362663 CDS YP_671569.1 110643839 4190866 complement(3872698..3873060) 1 NC_008253.1 hypothetical protein 3873060 4190866 ECP_3696 Escherichia coli 536 hypothetical protein YP_671569.1 3872698 R 362663 CDS YP_671570.1 110643840 4190867 3873597..3875510 1 NC_008253.1 PTS system mannitol-specific transporter subunit IIABC 3875510 4190867 ECP_3697 Escherichia coli 536 PTS system mannitol-specific transporter subunit IIABC YP_671570.1 3873597 D 362663 CDS YP_671571.1 110643841 4190868 3876016..3877179 1 NC_008253.1 mannitol-1-phosphate 5-dehydrogenase 3877179 4190868 ECP_3698 Escherichia coli 536 mannitol-1-phosphate 5-dehydrogenase YP_671571.1 3876016 D 362663 CDS YP_671572.1 110643842 4190869 3877179..3877766 1 NC_008253.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 3877766 mtlR 4190869 mtlR Escherichia coli 536 mannitol repressor protein YP_671572.1 3877179 D 362663 CDS YP_671573.1 110643843 4190870 complement(3877777..3877986) 1 NC_008253.1 hypothetical protein 3877986 4190870 ECP_3700 Escherichia coli 536 hypothetical protein YP_671573.1 3877777 R 362663 CDS YP_671574.1 110643844 4190871 3878270..3878632 1 NC_008253.1 hypothetical protein 3878632 4190871 ECP_3701 Escherichia coli 536 hypothetical protein YP_671574.1 3878270 D 362663 CDS YP_671575.1 110643845 4190872 3879191..3879874 1 NC_008253.1 hypothetical protein 3879874 4190872 ECP_3702 Escherichia coli 536 hypothetical protein YP_671575.1 3879191 D 362663 CDS YP_671576.1 110643846 4190873 3879918..3884792 1 NC_008253.1 hemagglutinin/invasin 3884792 4190873 ECP_3703 Escherichia coli 536 hemagglutinin/invasin YP_671576.1 3879918 D 362663 CDS YP_671577.1 110643847 4190274 3885204..3886859 1 NC_008253.1 L-lactate permease 3886859 4190274 ECP_3704 Escherichia coli 536 L-lactate permease YP_671577.1 3885204 D 362663 CDS YP_671578.1 110643848 4190275 3886859..3887635 1 NC_008253.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3887635 4190275 ECP_3705 Escherichia coli 536 DNA-binding transcriptional repressor LldR YP_671578.1 3886859 D 362663 CDS YP_671579.1 110643849 4190276 3887632..3888822 1 NC_008253.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3888822 lldD 4190276 lldD Escherichia coli 536 L-lactate dehydrogenase YP_671579.1 3887632 D 362663 CDS YP_671580.1 110643850 4190277 3888870..3889343 1 NC_008253.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 3889343 4190277 ECP_3707 Escherichia coli 536 tRNA/rRNA methyltransferase YibK YP_671580.1 3888870 D 362663 CDS YP_671581.1 110643851 4190278 complement(3889398..3890219) 1 NC_008253.1 catalyzes the O-acetylation of serine; serine acetyltransferase 3890219 cysE 4190278 cysE Escherichia coli 536 serine acetyltransferase YP_671581.1 3889398 R 362663 CDS YP_671582.1 110643852 4190279 complement(3890299..3891318) 1 NC_008253.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3891318 gpsA 4190279 gpsA Escherichia coli 536 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_671582.1 3890299 R 362663 CDS YP_671583.1 110643853 4190280 complement(3891318..3891785) 1 NC_008253.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 3891785 4190280 ECP_3710 Escherichia coli 536 preprotein translocase subunit SecB YP_671583.1 3891318 R 362663 CDS YP_671584.1 110643854 4190281 complement(3891849..3892100) 1 NC_008253.1 glutaredoxin 3 3892100 4190281 ECP_3711 Escherichia coli 536 glutaredoxin 3 YP_671584.1 3891849 R 362663 CDS YP_671585.1 110643855 4190282 complement(3892241..3892672) 1 NC_008253.1 hypothetical protein 3892672 4190282 ECP_3712 Escherichia coli 536 hypothetical protein YP_671585.1 3892241 R 362663 CDS YP_671586.1 110643856 4190283 3892917..3894461 1 NC_008253.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3894461 4190283 ECP_3713 Escherichia coli 536 phosphoglyceromutase YP_671586.1 3892917 D 362663 CDS YP_671587.1 110643857 4190284 3894471..3895754 1 NC_008253.1 hypothetical protein 3895754 4190284 ECP_3714 Escherichia coli 536 hypothetical protein YP_671587.1 3894471 D 362663 CDS YP_671588.1 110643858 4190285 3895758..3896717 1 NC_008253.1 hypothetical protein 3896717 4190285 ECP_3715 Escherichia coli 536 hypothetical protein YP_671588.1 3895758 D 362663 CDS YP_671589.1 110643859 4190286 complement(3896704..3897738) 1 NC_008253.1 glycosyl transferase family protein 3897738 4190286 ECP_3716 Escherichia coli 536 glycosyl transferase family protein YP_671589.1 3896704 R 362663 CDS YP_671590.1 110643860 4190287 complement(3897977..3899002) 1 NC_008253.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 3899002 tdh 4190287 tdh Escherichia coli 536 L-threonine 3-dehydrogenase YP_671590.1 3897977 R 362663 CDS YP_671591.1 110643861 4190288 complement(3899012..3900208) 1 NC_008253.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 3900208 4190288 ECP_3718 Escherichia coli 536 2-amino-3-ketobutyrate CoA ligase YP_671591.1 3899012 R 362663 CDS YP_671592.1 110643862 4190289 3900422..3901354 1 NC_008253.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3901354 rfaD 4190289 rfaD Escherichia coli 536 ADP-L-glycero-D-manno-heptose-6-epimerase YP_671592.1 3900422 D 362663 CDS YP_671593.1 110643863 4190290 3901364..3902410 1 NC_008253.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3902410 4190290 ECP_3720 Escherichia coli 536 ADP-heptose--LPS heptosyltransferase YP_671593.1 3901364 D 362663 CDS YP_671594.1 110643864 4190291 3902414..3903394 1 NC_008253.1 ADP-heptose--LPS heptosyltransferase 3903394 4190291 ECP_3721 Escherichia coli 536 ADP-heptose--LPS heptosyltransferase YP_671594.1 3902414 D 362663 CDS YP_671595.1 110643865 4190292 complement(3903464..3904717) 1 NC_008253.1 lipid A-core:surface polymer ligase WaaL 3904717 4190292 ECP_3722 Escherichia coli 536 lipid A-core:surface polymer ligase WaaL YP_671595.1 3903464 R 362663 CDS YP_671596.1 110643866 4190293 complement(3904763..3905746) 1 NC_008253.1 beta1,3-glucosyltransferase WaaV 3905746 4190293 ECP_3723 Escherichia coli 536 beta1,3-glucosyltransferase WaaV YP_671596.1 3904763 R 362663 CDS YP_671597.1 110643867 4189297 complement(3905828..3906856) 1 NC_008253.1 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW 3906856 4189297 ECP_3724 Escherichia coli 536 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW YP_671597.1 3905828 R 362663 CDS YP_671598.1 110643868 4189298 complement(3906882..3907574) 1 NC_008253.1 lipopolysaccharide core biosynthesis protein 3907574 4189298 ECP_3725 Escherichia coli 536 lipopolysaccharide core biosynthesis protein YP_671598.1 3906882 R 362663 CDS YP_671599.1 110643869 4189299 complement(3907584..3908579) 1 NC_008253.1 UDP-galactose:(glucosyl) LPS alpha1,2-galactosyltransferase WaaT 3908579 4189299 ECP_3726 Escherichia coli 536 UDP-galactose:(glucosyl) LPS alpha1,2-galactosyltransferase WaaT YP_671599.1 3907584 R 362663 CDS YP_671600.1 110643870 4189300 complement(3908596..3909612) 1 NC_008253.1 UDP-glucose:(glucosyl) LPS alpha1,3-glucosyltransferase WaaO 3909612 4189300 ECP_3727 Escherichia coli 536 UDP-glucose:(glucosyl) LPS alpha1,3-glucosyltransferase WaaO YP_671600.1 3908596 R 362663 CDS YP_671601.1 110643871 4189301 complement(3909628..3910425) 1 NC_008253.1 lipopolysaccharide core biosynthesis protein WaaP 3910425 4189301 ECP_3728 Escherichia coli 536 lipopolysaccharide core biosynthesis protein WaaP YP_671601.1 3909628 R 362663 CDS YP_671602.1 110643872 4189302 complement(3910418..3911542) 1 NC_008253.1 UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG 3911542 4189302 ECP_3729 Escherichia coli 536 UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG YP_671602.1 3910418 R 362663 CDS YP_671603.1 110643873 4189303 complement(3911539..3912561) 1 NC_008253.1 lipopolysaccharide core biosynthesis protein 3912561 4189303 ECP_3730 Escherichia coli 536 lipopolysaccharide core biosynthesis protein YP_671603.1 3911539 R 362663 CDS YP_671604.1 110643874 4189304 3913010..3914287 1 NC_008253.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3914287 4189304 ECP_3731 Escherichia coli 536 3-deoxy-D-manno-octulosonic-acid transferase YP_671604.1 3913010 D 362663 CDS YP_671605.1 110643875 4189305 3914295..3914774 1 NC_008253.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3914774 coaD 4189305 coaD Escherichia coli 536 phosphopantetheine adenylyltransferase YP_671605.1 3914295 D 362663 CDS YP_671606.1 110643876 4189306 complement(3914813..3915622) 1 NC_008253.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 3915622 4189306 ECP_3733 Escherichia coli 536 formamidopyrimidine-DNA glycosylase YP_671606.1 3914813 R 362663 CDS YP_671607.1 110643877 4189307 complement(3915720..3915887) 1 NC_008253.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 3915887 rpmG 4189307 rpmG Escherichia coli 536 50S ribosomal protein L33 YP_671607.1 3915720 R 362663 CDS YP_671608.1 110643878 4189308 complement(3915908..3916144) 1 NC_008253.1 required for 70S ribosome assembly; 50S ribosomal protein L28 3916144 rpmB 4189308 rpmB Escherichia coli 536 50S ribosomal protein L28 YP_671608.1 3915908 R 362663 CDS YP_671609.1 110643879 4189309 complement(3916361..3917005) 1 NC_008253.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 3917005 radC 4189309 radC Escherichia coli 536 DNA repair protein RadC YP_671609.1 3916361 R 362663 CDS YP_671610.1 110643880 4189310 3917201..3918421 1 NC_008253.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3918421 4189310 ECP_3737 Escherichia coli 536 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_671610.1 3917201 D 362663 CDS YP_671611.1 110643881 4189311 3918399..3918857 1 NC_008253.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3918857 dut 4189311 dut Escherichia coli 536 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_671611.1 3918399 D 362663 CDS YP_671612.1 110643882 4189312 3918964..3919560 1 NC_008253.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3919560 slmA 4189312 slmA Escherichia coli 536 nucleoid occlusion protein YP_671612.1 3918964 D 362663 CDS YP_671613.1 110643883 4189313 complement(3919597..3920238) 1 NC_008253.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 3920238 pyrE 4189313 pyrE Escherichia coli 536 orotate phosphoribosyltransferase YP_671613.1 3919597 R 362663 CDS YP_671614.1 110643884 4189314 complement(3920304..3921020) 1 NC_008253.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 3921020 rph 4189314 rph Escherichia coli 536 ribonuclease PH YP_671614.1 3920304 R 362663 CDS YP_671615.1 110643885 4189315 3921147..3922010 1 NC_008253.1 hypothetical protein 3922010 4189315 ECP_3742 Escherichia coli 536 hypothetical protein YP_671615.1 3921147 D 362663 CDS YP_671616.1 110643886 4191267 3922231..3923055 1 NC_008253.1 DNA-damage-inducible protein D 3923055 dinD 4191267 dinD Escherichia coli 536 DNA-damage-inducible protein D YP_671616.1 3922231 D 362663 CDS YP_671617.1 110643887 4191268 3923347..3923964 1 NC_008253.1 hypothetical protein 3923964 4191268 ECP_3744 Escherichia coli 536 hypothetical protein YP_671617.1 3923347 D 362663 CDS YP_671618.1 110643888 4191269 complement(3923961..3925646) 1 NC_008253.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 3925646 ligB 4191269 ligB Escherichia coli 536 NAD-dependent DNA ligase LigB YP_671618.1 3923961 R 362663 CDS YP_671619.1 110643889 4191270 3925901..3926524 1 NC_008253.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3926524 gmk 4191270 gmk Escherichia coli 536 guanylate kinase YP_671619.1 3925901 D 362663 CDS YP_671620.1 110643890 4191271 3926579..3926854 1 NC_008253.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3926854 rpoZ 4191271 rpoZ Escherichia coli 536 DNA-directed RNA polymerase subunit omega YP_671620.1 3926579 D 362663 CDS YP_671621.1 110643891 4191272 3926873..3928981 1 NC_008253.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3928981 4191272 ECP_3748 Escherichia coli 536 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_671621.1 3926873 D 362663 CDS YP_671622.1 110643892 4191273 3928988..3929677 1 NC_008253.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3929677 4191273 ECP_3749 Escherichia coli 536 tRNA guanosine-2'-O-methyltransferase YP_671622.1 3928988 D 362663 CDS YP_671623.1 110643893 4191274 3929683..3931764 1 NC_008253.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3931764 4191274 ECP_3750 Escherichia coli 536 ATP-dependent DNA helicase RecG YP_671623.1 3929683 D 362663 CDS YP_671624.1 110643894 4191275 complement(3931798..3933003) 1 NC_008253.1 sodium/glutamate symport carrier protein 3933003 4191275 ECP_3751 Escherichia coli 536 sodium/glutamate symport carrier protein YP_671624.1 3931798 R 362663 CDS YP_671625.1 110643895 4191276 3933283..3934674 1 NC_008253.1 purine permease YicE 3934674 4191276 ECP_3752 Escherichia coli 536 purine permease YicE YP_671625.1 3933283 D 362663 CDS YP_671626.1 110643896 4191277 3934771..3936504 1 NC_008253.1 hypothetical protein 3936504 4191277 ECP_3753 Escherichia coli 536 hypothetical protein YP_671626.1 3934771 D 362663 CDS YP_671627.1 110643897 4191278 complement(3936548..3937228) 1 NC_008253.1 hypothetical protein 3937228 4191278 ECP_3754 Escherichia coli 536 hypothetical protein YP_671627.1 3936548 R 362663 CDS YP_671628.1 110643898 4191279 complement(3937209..3938141) 1 NC_008253.1 hypothetical protein 3938141 4191279 ECP_3755 Escherichia coli 536 hypothetical protein YP_671628.1 3937209 R 362663 CDS YP_671629.1 110643899 4191280 complement(3938189..3939049) 1 NC_008253.1 hypothetical protein 3939049 4191280 ECP_3756 Escherichia coli 536 hypothetical protein YP_671629.1 3938189 R 362663 CDS YP_671630.1 110643900 4191281 complement(3939130..3939981) 1 NC_008253.1 fructose-bisphosphate aldolase class-II 3939981 4191281 ECP_3757 Escherichia coli 536 fructose-bisphosphate aldolase class-II YP_671630.1 3939130 R 362663 CDS YP_671631.1 110643901 4191282 complement(3939993..3941084) 1 NC_008253.1 PTS enzyme-II fructose 3941084 4191282 ECP_3758 Escherichia coli 536 PTS enzyme-II fructose YP_671631.1 3939993 R 362663 CDS YP_671632.1 110643902 4191283 complement(3941109..3941423) 1 NC_008253.1 PTS system, fructose-like-2 IIB component 1 3941423 4191283 ECP_3759 Escherichia coli 536 PTS system, fructose-like-2 IIB component 1 YP_671632.1 3941109 R 362663 CDS YP_671633.1 110643903 4191284 complement(3941441..3941911) 1 NC_008253.1 phosphotransferase system (PTS), fructose-specific 3941911 4191284 ECP_3760 Escherichia coli 536 phosphotransferase system (PTS), fructose-specific YP_671633.1 3941441 R 362663 CDS YP_671634.1 110643904 4191285 complement(3941938..3943491) 1 NC_008253.1 transcriptional antiterminator 3943491 4191285 ECP_3761 Escherichia coli 536 transcriptional antiterminator YP_671634.1 3941938 R 362663 CDS YP_671635.1 110643905 4191286 complement(3943786..3946104) 1 NC_008253.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 3946104 4191286 ECP_3762 Escherichia coli 536 alpha-xylosidase YP_671635.1 3943786 R 362663 CDS YP_671636.1 110643906 4191462 complement(3946114..3947541) 1 NC_008253.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 3947541 4191462 ECP_3763 Escherichia coli 536 transporter YP_671636.1 3946114 R 362663 CDS YP_671637.1 110643907 4191464 3948173..3949354 1 NC_008253.1 phage integrase 3949354 4191464 ECP_3765 Escherichia coli 536 phage integrase YP_671637.1 3948173 D 362663 CDS YP_671638.1 110643908 4191465 3949965..3950912 1 NC_008253.1 type II 5-cytosoine methyltransferase 3950912 4191465 ECP_3766 Escherichia coli 536 type II 5-cytosoine methyltransferase YP_671638.1 3949965 D 362663 CDS YP_671639.1 110643909 4191466 3950924..3951841 1 NC_008253.1 type II 5-cytosoine methyltransferase 3951841 4191466 ECP_3767 Escherichia coli 536 type II 5-cytosoine methyltransferase YP_671639.1 3950924 D 362663 CDS YP_671640.1 110643910 4191467 3951905..3953161 1 NC_008253.1 hypothetical protein 3953161 4191467 ECP_3768 Escherichia coli 536 hypothetical protein YP_671640.1 3951905 D 362663 CDS YP_671641.1 110643911 4191468 3953679..3953927 1 NC_008253.1 hypothetical protein 3953927 4191468 ECP_3769 Escherichia coli 536 hypothetical protein YP_671641.1 3953679 D 362663 CDS YP_671642.1 110643912 4191469 complement(3954069..3954209) 1 NC_008253.1 hypothetical protein 3954209 4191469 ECP_3770 Escherichia coli 536 hypothetical protein YP_671642.1 3954069 R 362663 CDS YP_671643.1 110643913 4191470 3954835..3955068 1 NC_008253.1 hypothetical protein 3955068 4191470 ECP_3771 Escherichia coli 536 hypothetical protein YP_671643.1 3954835 D 362663 CDS YP_671644.1 110643914 4191471 complement(3955045..3955698) 1 NC_008253.1 transposase 3955698 4191471 ECP_3772 Escherichia coli 536 transposase YP_671644.1 3955045 R 362663 CDS YP_671645.1 110643915 4191472 complement(3955801..3956583) 1 NC_008253.1 transposase/IS protein 3956583 4191472 ECP_3773 Escherichia coli 536 transposase/IS protein YP_671645.1 3955801 R 362663 CDS YP_671646.1 110643916 4191473 complement(3956580..3957602) 1 NC_008253.1 transposase 3957602 4191473 ECP_3774 Escherichia coli 536 transposase YP_671646.1 3956580 R 362663 CDS YP_671647.1 110643917 4191474 3957659..3958183 1 NC_008253.1 hypothetical protein 3958183 4191474 ECP_3775 Escherichia coli 536 hypothetical protein YP_671647.1 3957659 D 362663 CDS YP_671648.1 110643918 4191475 complement(3958381..3958932) 1 NC_008253.1 MarR family transcriptional regulator 3958932 4191475 ECP_3776 Escherichia coli 536 MarR family transcriptional regulator YP_671648.1 3958381 R 362663 CDS YP_671649.1 110643919 4191476 complement(3958961..3959170) 1 NC_008253.1 hypothetical protein 3959170 4191476 ECP_3777 Escherichia coli 536 hypothetical protein YP_671649.1 3958961 R 362663 CDS YP_671650.1 110643920 4191477 complement(3959407..3959619) 1 NC_008253.1 hypothetical protein 3959619 4191477 ECP_3778 Escherichia coli 536 hypothetical protein YP_671650.1 3959407 R 362663 CDS YP_671651.1 110643921 4191478 3959662..3959808 1 NC_008253.1 hypothetical protein 3959808 4191478 ECP_3779 Escherichia coli 536 hypothetical protein YP_671651.1 3959662 D 362663 CDS YP_671652.1 110643922 4191479 complement(3960065..3960433) 1 NC_008253.1 hypothetical protein 3960433 4191479 ECP_3780 Escherichia coli 536 hypothetical protein YP_671652.1 3960065 R 362663 CDS YP_671653.1 110643923 4191520 3960415..3960690 1 NC_008253.1 hypothetical protein 3960690 4191520 ECP_3781 Escherichia coli 536 hypothetical protein YP_671653.1 3960415 D 362663 CDS YP_671654.1 110643924 4191521 complement(3960709..3961788) 1 NC_008253.1 F17-like fimbril adhesin subunit 3961788 4191521 ECP_3782 Escherichia coli 536 F17-like fimbril adhesin subunit YP_671654.1 3960709 R 362663 CDS YP_671655.1 110643925 4191522 complement(3961785..3964319) 1 NC_008253.1 F17-like fimbrial usher 3964319 4191522 ECP_3783 Escherichia coli 536 F17-like fimbrial usher YP_671655.1 3961785 R 362663 CDS YP_671656.1 110643926 4191523 complement(3964327..3965052) 1 NC_008253.1 F17-like fimbrial chaperone 3965052 4191523 ECP_3784 Escherichia coli 536 F17-like fimbrial chaperone YP_671656.1 3964327 R 362663 CDS YP_671657.1 110643927 4191524 complement(3965110..3965661) 1 NC_008253.1 F17 fimbrial protein 3965661 4191524 ECP_3785 Escherichia coli 536 F17 fimbrial protein YP_671657.1 3965110 R 362663 CDS YP_671658.1 110643928 4191525 3965689..3965955 1 NC_008253.1 hypothetical protein 3965955 4191525 ECP_3786 Escherichia coli 536 hypothetical protein YP_671658.1 3965689 D 362663 CDS YP_671659.1 110643929 4191526 complement(3966233..3966655) 1 NC_008253.1 hypothetical protein 3966655 4191526 ECP_3787 Escherichia coli 536 hypothetical protein YP_671659.1 3966233 R 362663 CDS YP_671660.1 110643930 4191527 complement(3966658..3967887) 1 NC_008253.1 FMN-dependent dehydrogenase 3967887 4191527 ECP_3788 Escherichia coli 536 FMN-dependent dehydrogenase YP_671660.1 3966658 R 362663 CDS YP_671661.1 110643931 4191528 complement(3967926..3968474) 1 NC_008253.1 hypothetical protein 3968474 4191528 ECP_3789 Escherichia coli 536 hypothetical protein YP_671661.1 3967926 R 362663 CDS YP_671662.1 110643932 4191529 3968446..3969285 1 NC_008253.1 transcription regulator protein 3969285 4191529 ECP_3790 Escherichia coli 536 transcription regulator protein YP_671662.1 3968446 D 362663 CDS YP_671663.1 110643933 4191530 3969269..3969577 1 NC_008253.1 hypothetical protein 3969577 4191530 ECP_3791 Escherichia coli 536 hypothetical protein YP_671663.1 3969269 D 362663 CDS YP_671664.1 110643934 4191531 complement(3969628..3969846) 1 NC_008253.1 hypothetical protein 3969846 4191531 ECP_3792 Escherichia coli 536 hypothetical protein YP_671664.1 3969628 R 362663 CDS YP_671665.1 110643935 4191532 complement(3970073..3970210) 1 NC_008253.1 hypothetical protein 3970210 4191532 ECP_3793 Escherichia coli 536 hypothetical protein YP_671665.1 3970073 R 362663 CDS YP_671666.1 110643936 4191533 3970254..3970457 1 NC_008253.1 hypothetical protein 3970457 4191533 ECP_3794 Escherichia coli 536 hypothetical protein YP_671666.1 3970254 D 362663 CDS YP_671667.1 110643937 4191534 3970450..3970740 1 NC_008253.1 transposase 3970740 4191534 ECP_3795 Escherichia coli 536 transposase YP_671667.1 3970450 D 362663 CDS YP_671668.1 110643938 4191535 3970733..3972415 1 NC_008253.1 hypothetical protein 3972415 4191535 ECP_3796 Escherichia coli 536 hypothetical protein YP_671668.1 3970733 D 362663 CDS YP_671669.1 110643939 4191536 complement(3972603..3972884) 1 NC_008253.1 hypothetical protein 3972884 4191536 ECP_3797 Escherichia coli 536 hypothetical protein YP_671669.1 3972603 R 362663 CDS YP_671670.1 110643940 4191537 3973972..3974538 1 NC_008253.1 hypothetical protein 3974538 4191537 ECP_3798 Escherichia coli 536 hypothetical protein YP_671670.1 3973972 D 362663 CDS YP_671671.1 110643941 4191538 3974653..3975357 1 NC_008253.1 hypothetical protein 3975357 4191538 ECP_3799 Escherichia coli 536 hypothetical protein YP_671671.1 3974653 D 362663 CDS YP_671672.1 110643942 4191539 3975426..3975659 1 NC_008253.1 regulatory protein 3975659 4191539 ECP_3800 Escherichia coli 536 regulatory protein YP_671672.1 3975426 D 362663 CDS YP_671673.1 110643943 4191609 3975656..3975814 1 NC_008253.1 hypothetical protein 3975814 4191609 ECP_3801 Escherichia coli 536 hypothetical protein YP_671673.1 3975656 D 362663 CDS YP_671674.1 110643944 4191610 3975890..3976072 1 NC_008253.1 hypothetical protein 3976072 4191610 ECP_3802 Escherichia coli 536 hypothetical protein YP_671674.1 3975890 D 362663 CDS YP_671675.1 110643945 4191611 3976106..3976387 1 NC_008253.1 hypothetical protein 3976387 4191611 ECP_3803 Escherichia coli 536 hypothetical protein YP_671675.1 3976106 D 362663 CDS YP_671676.1 110643946 4191612 complement(3976498..3976962) 1 NC_008253.1 transposase 3976962 4191612 ECP_3804 Escherichia coli 536 transposase YP_671676.1 3976498 R 362663 CDS YP_671677.1 110643947 4191613 complement(3977161..3977388) 1 NC_008253.1 hypothetical protein 3977388 4191613 ECP_3805 Escherichia coli 536 hypothetical protein YP_671677.1 3977161 R 362663 CDS YP_671678.1 110643948 4191614 complement(3977411..3978250) 1 NC_008253.1 transposase 3978250 4191614 ECP_3806 Escherichia coli 536 transposase YP_671678.1 3977411 R 362663 CDS YP_671679.1 110643949 4191615 complement(3978277..3978579) 1 NC_008253.1 transposase 3978579 4191615 ECP_3807 Escherichia coli 536 transposase YP_671679.1 3978277 R 362663 CDS YP_671680.1 110643950 4191616 complement(3978847..3979020) 1 NC_008253.1 hypothetical protein 3979020 4191616 ECP_3808 Escherichia coli 536 hypothetical protein YP_671680.1 3978847 R 362663 CDS YP_671681.1 110643951 4191617 3979072..3979209 1 NC_008253.1 hypothetical protein 3979209 4191617 ECP_3809 Escherichia coli 536 hypothetical protein YP_671681.1 3979072 D 362663 CDS YP_671682.1 110643952 4191618 complement(3979617..3980447) 1 NC_008253.1 CS12 fimbrial-like upstream regulatory protein 3980447 4191618 ECP_3810 Escherichia coli 536 CS12 fimbrial-like upstream regulatory protein YP_671682.1 3979617 R 362663 CDS YP_671683.1 110643953 4191619 3980576..3981229 1 NC_008253.1 hypothetical protein 3981229 4191619 ECP_3811 Escherichia coli 536 hypothetical protein YP_671683.1 3980576 D 362663 CDS YP_671684.1 110643954 4191620 3981285..3981986 1 NC_008253.1 CS12 fimbria chaperone FasB-like protein 3981986 4191620 ECP_3812 Escherichia coli 536 CS12 fimbria chaperone FasB-like protein YP_671684.1 3981285 D 362663 CDS YP_671685.1 110643955 4191621 3981967..3982398 1 NC_008253.1 CS12 fimbria chaperone protein 3982398 4191621 ECP_3813 Escherichia coli 536 CS12 fimbria chaperone protein YP_671685.1 3981967 D 362663 CDS YP_671686.1 110643956 4191622 3982471..3984978 1 NC_008253.1 CS12 fimbria outer membrane usher protein 3984978 4191622 ECP_3814 Escherichia coli 536 CS12 fimbria outer membrane usher protein YP_671686.1 3982471 D 362663 CDS YP_671687.1 110643957 4191623 3984966..3985418 1 NC_008253.1 CS12 fimbria chaperone protein 3985418 4191623 ECP_3815 Escherichia coli 536 CS12 fimbria chaperone protein YP_671687.1 3984966 D 362663 CDS YP_671688.1 110643958 4191624 3985408..3985956 1 NC_008253.1 CS12 fimbria minor subunit protein 3985956 4191624 ECP_3816 Escherichia coli 536 CS12 fimbria minor subunit protein YP_671688.1 3985408 D 362663 CDS YP_671689.1 110643959 4191625 3985976..3987241 1 NC_008253.1 FasG-like protein 3987241 4191625 ECP_3817 Escherichia coli 536 FasG-like protein YP_671689.1 3985976 D 362663 CDS YP_671690.1 110643960 4191626 complement(3987475..3988671) 1 NC_008253.1 transposase 3988671 4191626 ECP_3818 Escherichia coli 536 transposase YP_671690.1 3987475 R 362663 CDS YP_671691.1 110643961 4191627 complement(3988780..3988956) 1 NC_008253.1 hypothetical protein 3988956 4191627 ECP_3819 Escherichia coli 536 hypothetical protein YP_671691.1 3988780 R 362663 CDS YP_671692.1 110643962 4191725 complement(3988997..3989359) 1 NC_008253.1 hypothetical protein 3989359 4191725 ECP_3820 Escherichia coli 536 hypothetical protein YP_671692.1 3988997 R 362663 CDS YP_671693.1 110643963 4191726 3989342..3989521 1 NC_008253.1 hypothetical protein 3989521 4191726 ECP_3821 Escherichia coli 536 hypothetical protein YP_671693.1 3989342 D 362663 CDS YP_671694.1 110643964 4191727 3989622..3990458 1 NC_008253.1 ABC transporter ATP-binding protein 3990458 4191727 ECP_3822 Escherichia coli 536 ABC transporter ATP-binding protein YP_671694.1 3989622 D 362663 CDS YP_671695.1 110643965 4191728 3990383..3991309 1 NC_008253.1 ABC-transporter membrane protein 3991309 4191728 ECP_3823 Escherichia coli 536 ABC-transporter membrane protein YP_671695.1 3990383 D 362663 CDS YP_671696.1 110643966 4191729 3991353..3992231 1 NC_008253.1 periplasmic binding protein 3992231 4191729 ECP_3824 Escherichia coli 536 periplasmic binding protein YP_671696.1 3991353 D 362663 CDS YP_671697.1 110643967 4191730 3992418..3992630 1 NC_008253.1 hypothetical protein 3992630 4191730 ECP_3825 Escherichia coli 536 hypothetical protein YP_671697.1 3992418 D 362663 CDS YP_671698.1 110643968 4191731 3993046..3993558 1 NC_008253.1 hemolysin-activating lysine-acyltransferase HlyC 3993558 4191731 ECP_3826 Escherichia coli 536 hemolysin-activating lysine-acyltransferase HlyC YP_671698.1 3993046 D 362663 CDS YP_671699.1 110643969 4191732 3993570..3996644 1 NC_008253.1 hemolysin A 3996644 4191732 ECP_3827 Escherichia coli 536 hemolysin A YP_671699.1 3993570 D 362663 CDS YP_671700.1 110643970 4191733 3996715..3998838 1 NC_008253.1 alpha-hemolysin translocation ATP-binding protein HlyB 3998838 4191733 ECP_3828 Escherichia coli 536 alpha-hemolysin translocation ATP-binding protein HlyB YP_671700.1 3996715 D 362663 CDS YP_671701.1 110643971 4191734 3998857..4000293 1 NC_008253.1 hemolysin D 4000293 4191734 ECP_3829 Escherichia coli 536 hemolysin D YP_671701.1 3998857 D 362663 CDS YP_671702.1 110643972 4191735 4000591..4001511 1 NC_008253.1 urea transporter 4001511 4191735 ECP_3830 Escherichia coli 536 urea transporter YP_671702.1 4000591 D 362663 CDS YP_671703.1 110643973 4191736 4001753..4002985 1 NC_008253.1 phosphoadenosine phosphosulfate reductase 4002985 4191736 ECP_3831 Escherichia coli 536 phosphoadenosine phosphosulfate reductase YP_671703.1 4001753 D 362663 CDS YP_671704.1 110643974 4191737 4002970..4003614 1 NC_008253.1 ParB-like nuclease 4003614 4191737 ECP_3832 Escherichia coli 536 ParB-like nuclease YP_671704.1 4002970 D 362663 CDS YP_671705.1 110643975 4191738 complement(4003655..4003861) 1 NC_008253.1 transposase 4003861 4191738 ECP_3833 Escherichia coli 536 transposase YP_671705.1 4003655 R 362663 CDS YP_671706.1 110643976 4191739 complement(4003883..4004413) 1 NC_008253.1 transposase 4004413 4191739 ECP_3834 Escherichia coli 536 transposase YP_671706.1 4003883 R 362663 CDS YP_671707.1 110643977 4191740 4005143..4005958 1 NC_008253.1 AraC family transcriptional regulator 4005958 4191740 ECP_3835 Escherichia coli 536 AraC family transcriptional regulator YP_671707.1 4005143 D 362663 CDS YP_671708.1 110643978 4191741 4006163..4006492 1 NC_008253.1 hypothetical protein 4006492 4191741 ECP_3836 Escherichia coli 536 hypothetical protein YP_671708.1 4006163 D 362663 CDS YP_671709.1 110643979 4191742 4007002..4007694 1 NC_008253.1 transposase 4007694 4191742 ECP_3837 Escherichia coli 536 transposase YP_671709.1 4007002 D 362663 CDS YP_671710.1 110643980 4191743 complement(4008032..4009264) 1 NC_008253.1 reverse transcriptase 4009264 4191743 ECP_3838 Escherichia coli 536 reverse transcriptase YP_671710.1 4008032 R 362663 CDS YP_671711.1 110643981 4191744 4009478..4009678 1 NC_008253.1 hypothetical protein 4009678 4191744 ECP_3839 Escherichia coli 536 hypothetical protein YP_671711.1 4009478 D 362663 CDS YP_671712.1 110643982 4188413 complement(4009726..4011057) 1 NC_008253.1 transposase 4011057 4188413 ECP_3840 Escherichia coli 536 transposase YP_671712.1 4009726 R 362663 CDS YP_671713.1 110643983 4188414 4011116..4012138 1 NC_008253.1 transposase 4012138 4188414 ECP_3841 Escherichia coli 536 transposase YP_671713.1 4011116 D 362663 CDS YP_671714.1 110643984 4188415 4012135..4012917 1 NC_008253.1 transposase/IS protein 4012917 4188415 ECP_3842 Escherichia coli 536 transposase/IS protein YP_671714.1 4012135 D 362663 CDS YP_671715.1 110643985 4188416 complement(4012968..4014032) 1 NC_008253.1 transposase 4014032 4188416 ECP_3843 Escherichia coli 536 transposase YP_671715.1 4012968 R 362663 CDS YP_671716.1 110643986 4188417 complement(4014160..4014429) 1 NC_008253.1 IS orf 4014429 4188417 ECP_3844 Escherichia coli 536 IS orf YP_671716.1 4014160 R 362663 CDS YP_671717.1 110643987 4188418 complement(4014426..4014806) 1 NC_008253.1 transposase 4014806 4188418 ECP_3845 Escherichia coli 536 transposase YP_671717.1 4014426 R 362663 CDS YP_671718.1 110643988 4188419 complement(4015470..4015682) 1 NC_008253.1 hypothetical protein 4015682 4188419 ECP_3846 Escherichia coli 536 hypothetical protein YP_671718.1 4015470 R 362663 CDS YP_671719.1 110643989 4188420 complement(4015823..4016038) 1 NC_008253.1 hypothetical protein 4016038 4188420 ECP_3847 Escherichia coli 536 hypothetical protein YP_671719.1 4015823 R 362663 CDS YP_671720.1 110643990 4188421 complement(4016243..4016446) 1 NC_008253.1 hypothetical protein 4016446 4188421 ECP_3848 Escherichia coli 536 hypothetical protein YP_671720.1 4016243 R 362663 CDS YP_671721.1 110643991 4188422 complement(4016473..4016790) 1 NC_008253.1 transposase 4016790 4188422 ECP_3849 Escherichia coli 536 transposase YP_671721.1 4016473 R 362663 CDS YP_671722.1 110643992 4188423 4016935..4017819 1 NC_008253.1 hypothetical protein 4017819 4188423 ECP_3850 Escherichia coli 536 hypothetical protein YP_671722.1 4016935 D 362663 CDS YP_671723.1 110643993 4188424 4018022..4018702 1 NC_008253.1 hypothetical protein 4018702 4188424 ECP_3851 Escherichia coli 536 hypothetical protein YP_671723.1 4018022 D 362663 CDS YP_671724.1 110643994 4188425 4018745..4019527 1 NC_008253.1 hypothetical protein 4019527 4188425 ECP_3852 Escherichia coli 536 hypothetical protein YP_671724.1 4018745 D 362663 CDS YP_671725.1 110643995 4188426 4019533..4019766 1 NC_008253.1 hypothetical protein 4019766 4188426 ECP_3853 Escherichia coli 536 hypothetical protein YP_671725.1 4019533 D 362663 CDS YP_671726.1 110643996 4188427 4019856..4020674 1 NC_008253.1 hypothetical protein 4020674 4188427 ECP_3854 Escherichia coli 536 hypothetical protein YP_671726.1 4019856 D 362663 CDS YP_671727.1 110643997 4188428 4020766..4021251 1 NC_008253.1 antirestriction protein 4021251 4188428 ECP_3855 Escherichia coli 536 antirestriction protein YP_671727.1 4020766 D 362663 CDS YP_671728.1 110643998 4188429 4021266..4021742 1 NC_008253.1 radC-like protein 4021742 4188429 ECP_3856 Escherichia coli 536 radC-like protein YP_671728.1 4021266 D 362663 CDS YP_671729.1 110643999 4188430 4021805..4022026 1 NC_008253.1 hypothetical protein 4022026 4188430 ECP_3857 Escherichia coli 536 hypothetical protein YP_671729.1 4021805 D 362663 CDS YP_671730.1 110644000 4188431 4022100..4022468 1 NC_008253.1 hypothetical protein 4022468 4188431 ECP_3858 Escherichia coli 536 hypothetical protein YP_671730.1 4022100 D 362663 CDS YP_671731.1 110644001 4189048 4022558..4022932 1 NC_008253.1 hypothetical protein 4022932 4189048 ECP_3859 Escherichia coli 536 hypothetical protein YP_671731.1 4022558 D 362663 CDS YP_671732.1 110644002 4189049 4022929..4023408 1 NC_008253.1 hypothetical protein 4023408 4189049 ECP_3860 Escherichia coli 536 hypothetical protein YP_671732.1 4022929 D 362663 CDS YP_671733.1 110644003 4189050 4023375..4023617 1 NC_008253.1 hypothetical protein 4023617 4189050 ECP_3861 Escherichia coli 536 hypothetical protein YP_671733.1 4023375 D 362663 CDS YP_671734.1 110644004 4189051 4023701..4024546 1 NC_008253.1 hypothetical protein 4024546 4189051 ECP_3862 Escherichia coli 536 hypothetical protein YP_671734.1 4023701 D 362663 CDS YP_671735.1 110644005 4189052 4024777..4024998 1 NC_008253.1 hypothetical protein 4024998 4189052 ECP_3863 Escherichia coli 536 hypothetical protein YP_671735.1 4024777 D 362663 CDS YP_671736.1 110644006 4189053 4025139..4025507 1 NC_008253.1 hypothetical protein 4025507 4189053 ECP_3864 Escherichia coli 536 hypothetical protein YP_671736.1 4025139 D 362663 CDS YP_671737.1 110644007 4189054 4025804..4026727 1 NC_008253.1 hypothetical protein 4026727 4189054 ECP_3865 Escherichia coli 536 hypothetical protein YP_671737.1 4025804 D 362663 CDS YP_671738.1 110644008 4189055 complement(4026731..4027549) 1 NC_008253.1 hypothetical protein 4027549 4189055 ECP_3866 Escherichia coli 536 hypothetical protein YP_671738.1 4026731 R 362663 CDS YP_671739.1 110644009 4189056 4027771..4028064 1 NC_008253.1 hypothetical protein 4028064 4189056 ECP_3867 Escherichia coli 536 hypothetical protein YP_671739.1 4027771 D 362663 CDS YP_671740.2 162138274 4189057 complement(4028105..4029295) 1 NC_008253.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4029295 nepI 4189057 nepI Escherichia coli 536 ribonucleoside transporter YP_671740.2 4028105 R 362663 CDS YP_671741.1 110644011 4189058 complement(4029506..4029985) 1 NC_008253.1 hypothetical protein 4029985 4189058 ECP_3869 Escherichia coli 536 hypothetical protein YP_671741.1 4029506 R 362663 CDS YP_671742.1 110644012 4189059 complement(4030011..4031423) 1 NC_008253.1 xanthine/uracil permease 4031423 4189059 ECP_3870 Escherichia coli 536 xanthine/uracil permease YP_671742.1 4030011 R 362663 CDS YP_671743.1 110644013 4189060 4031520..4033286 1 NC_008253.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4033286 4189060 ECP_3871 Escherichia coli 536 cryptic adenine deaminase YP_671743.1 4031520 D 362663 CDS YP_671744.1 110644014 4189061 complement(4033332..4034723) 1 NC_008253.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4034723 uhpT 4189061 uhpT Escherichia coli 536 sugar phosphate antiporter YP_671744.1 4033332 R 362663 CDS YP_671745.1 110644015 4189062 complement(4034861..4036180) 1 NC_008253.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4036180 4189062 ECP_3873 Escherichia coli 536 regulatory protein UhpC YP_671745.1 4034861 R 362663 CDS YP_671746.1 110644016 4189063 complement(4036190..4037692) 1 NC_008253.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4037692 4189063 ECP_3874 Escherichia coli 536 sensory histidine kinase UhpB YP_671746.1 4036190 R 362663 CDS YP_671747.1 110644017 4189064 complement(4037692..4038282) 1 NC_008253.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4038282 4189064 ECP_3875 Escherichia coli 536 DNA-binding transcriptional activator UhpA YP_671747.1 4037692 R 362663 CDS YP_671748.1 110644018 4189065 4038594..4039556 1 NC_008253.1 hypothetical protein 4039556 4189065 ECP_3876 Escherichia coli 536 hypothetical protein YP_671748.1 4038594 D 362663 CDS YP_671749.1 110644019 4189066 complement(4039747..4040037) 1 NC_008253.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4040037 4189066 ECP_3877 Escherichia coli 536 acetolactate synthase 1 regulatory subunit YP_671749.1 4039747 R 362663 CDS YP_671750.1 110644020 4189067 complement(4040041..4041729) 1 NC_008253.1 acetolactate synthase catalytic subunit 4041729 4189067 ECP_3878 Escherichia coli 536 acetolactate synthase catalytic subunit YP_671750.1 4040041 R 362663 CDS YP_671751.1 110644021 4190479 4042328..4043518 1 NC_008253.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4043518 emrD 4190479 emrD Escherichia coli 536 multidrug resistance protein D YP_671751.1 4042328 D 362663 CDS YP_671752.1 110644022 4190480 complement(4043526..4044023) 1 NC_008253.1 hypothetical protein 4044023 4190480 ECP_3880 Escherichia coli 536 hypothetical protein YP_671752.1 4043526 R 362663 CDS YP_671753.1 110644023 4190481 complement(4044020..4044382) 1 NC_008253.1 hypothetical protein 4044382 4190481 ECP_3881 Escherichia coli 536 hypothetical protein YP_671753.1 4044020 R 362663 CDS YP_671754.1 110644024 4190482 complement(4044372..4044779) 1 NC_008253.1 hypothetical protein 4044779 4190482 ECP_3882 Escherichia coli 536 hypothetical protein YP_671754.1 4044372 R 362663 CDS YP_671755.1 110644025 4190483 complement(4044779..4046272) 1 NC_008253.1 sulfatase 4046272 4190483 ECP_3883 Escherichia coli 536 sulfatase YP_671755.1 4044779 R 362663 CDS YP_671756.1 110644026 4190484 complement(4046269..4047984) 1 NC_008253.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4047984 4190484 ECP_3884 Escherichia coli 536 symporter YidK YP_671756.1 4046269 R 362663 CDS YP_671757.1 110644027 4190485 4048151..4049017 1 NC_008253.1 transcriptional regulator YidL 4049017 4190485 ECP_3885 Escherichia coli 536 transcriptional regulator YidL YP_671757.1 4048151 D 362663 CDS YP_671758.1 110644028 4190486 complement(4049107..4050792) 1 NC_008253.1 hypothetical protein 4050792 4190486 ECP_3886 Escherichia coli 536 hypothetical protein YP_671758.1 4049107 R 362663 CDS YP_671759.2 229560207 4190487 complement(4050965..4051393) 1 NC_008253.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4051393 4190487 ECP_3887 Escherichia coli 536 heat shock chaperone IbpB YP_671759.2 4050965 R 362663 CDS YP_671760.1 110644030 4190488 complement(4051505..4051918) 1 NC_008253.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4051918 4190488 ECP_3888 Escherichia coli 536 heat shock protein IbpA YP_671760.1 4051505 R 362663 CDS YP_671761.1 110644031 4190489 4052149..4052556 1 NC_008253.1 hypothetical protein 4052556 4190489 ECP_3889 Escherichia coli 536 hypothetical protein YP_671761.1 4052149 D 362663 CDS YP_671762.1 110644032 4190490 complement(4052560..4053774) 1 NC_008253.1 hypothetical protein 4053774 4190490 ECP_3890 Escherichia coli 536 hypothetical protein YP_671762.1 4052560 R 362663 CDS YP_671763.1 110644033 4190491 4053854..4054975 1 NC_008253.1 FAD/NAD(P)-binding domain; oxidoreductase 4054975 4190491 ECP_3891 Escherichia coli 536 oxidoreductase YP_671763.1 4053854 D 362663 CDS YP_671764.1 110644034 4190492 complement(4054936..4056273) 1 NC_008253.1 D-galactonate transporter 4056273 4190492 ECP_3892 Escherichia coli 536 D-galactonate transporter YP_671764.1 4054936 R 362663 CDS YP_671765.1 110644035 4190493 complement(4056348..4057496) 1 NC_008253.1 bifunctional; galactonate dehydratase 4057496 4190493 ECP_3893 Escherichia coli 536 galactonate dehydratase YP_671765.1 4056348 R 362663 CDS YP_671766.1 110644036 4190494 complement(4057493..4058110) 1 NC_008253.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4058110 4190494 ECP_3894 Escherichia coli 536 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_671766.1 4057493 R 362663 CDS YP_671767.1 110644037 4190495 complement(4058094..4058972) 1 NC_008253.1 2-dehydro-3-deoxygalactonokinase 4058972 4190495 ECP_3895 Escherichia coli 536 2-dehydro-3-deoxygalactonokinase YP_671767.1 4058094 R 362663 CDS YP_671768.1 110644038 4190496 complement(4058969..4059658) 1 NC_008253.1 galactonate operon transcriptional repressor 4059658 4190496 ECP_3896 Escherichia coli 536 galactonate operon transcriptional repressor YP_671768.1 4058969 R 362663 CDS YP_671769.1 110644039 4190497 4059937..4060593 1 NC_008253.1 hypothetical protein 4060593 4190497 ECP_3897 Escherichia coli 536 hypothetical protein YP_671769.1 4059937 D 362663 CDS YP_671770.1 110644040 4188962 complement(4060637..4061449) 1 NC_008253.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4061449 4188962 ECP_3898 Escherichia coli 536 sugar phosphatase YP_671770.1 4060637 R 362663 CDS YP_671771.1 110644041 4188963 complement(4061564..4061962) 1 NC_008253.1 hypothetical protein 4061962 4188963 ECP_3899 Escherichia coli 536 hypothetical protein YP_671771.1 4061564 R 362663 CDS YP_671772.1 110644042 4188964 complement(4062202..4064616) 1 NC_008253.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4064616 gyrB 4188964 gyrB Escherichia coli 536 DNA gyrase subunit B YP_671772.1 4062202 R 362663 CDS YP_671773.1 110644043 4188965 complement(4064645..4065718) 1 NC_008253.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4065718 recF 4188965 recF Escherichia coli 536 recombination protein F YP_671773.1 4064645 R 362663 CDS YP_671774.1 110644044 4188966 complement(4065718..4066818) 1 NC_008253.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4066818 4188966 ECP_3902 Escherichia coli 536 DNA polymerase III subunit beta YP_671774.1 4065718 R 362663 CDS YP_671775.1 110644045 4188967 complement(4066823..4068157) 1 NC_008253.1 chromosomal replication initiator protein DnaA 4068157 4188967 ECP_3903 Escherichia coli 536 chromosomal replication initiator protein DnaA YP_671775.1 4066823 R 362663 CDS YP_671776.1 110644046 4188968 complement(4068740..4068880) 1 NC_008253.1 hypothetical protein 4068880 4188968 ECP_3904 Escherichia coli 536 hypothetical protein YP_671776.1 4068740 R 362663 CDS YP_671777.1 110644047 4188969 4069023..4069349 1 NC_008253.1 ribonuclease P protein component 4069349 4188969 ECP_3905 Escherichia coli 536 ribonuclease P protein component YP_671777.1 4069023 D 362663 CDS YP_671778.1 110644048 4188970 4069573..4071219 1 NC_008253.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4071219 4188970 ECP_3906 Escherichia coli 536 inner membrane protein translocase component YidC YP_671778.1 4069573 D 362663 CDS YP_671779.1 110644049 4188971 4071325..4072689 1 NC_008253.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4072689 trmE 4188971 trmE Escherichia coli 536 tRNA modification GTPase TrmE YP_671779.1 4071325 D 362663 CDS YP_671780.1 110644050 4188972 4073226..4074641 1 NC_008253.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4074641 tnaA 4188972 tnaA Escherichia coli 536 tryptophanase YP_671780.1 4073226 D 362663 CDS YP_671781.1 110644051 4188973 4074733..4075980 1 NC_008253.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4075980 4188973 ECP_3909 Escherichia coli 536 tryptophan permease TnaB YP_671781.1 4074733 D 362663 CDS YP_671782.1 110644052 4188974 4076112..4077287 1 NC_008253.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4077287 4188974 ECP_3910 Escherichia coli 536 multidrug efflux system protein MdtL YP_671782.1 4076112 D 362663 CDS YP_671783.1 110644053 4188975 4077334..4078221 1 NC_008253.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4078221 4188975 ECP_3911 Escherichia coli 536 DNA-binding transcriptional regulator YidZ YP_671783.1 4077334 D 362663 CDS YP_671784.1 110644054 4188976 4078366..4079127 1 NC_008253.1 hypothetical protein 4079127 4188976 ECP_3912 Escherichia coli 536 hypothetical protein YP_671784.1 4078366 D 362663 CDS YP_671785.1 110644055 4188977 4079149..4079715 1 NC_008253.1 hypothetical protein 4079715 4188977 ECP_3913 Escherichia coli 536 hypothetical protein YP_671785.1 4079149 D 362663 CDS YP_671786.1 110644056 4188978 complement(4079769..4081106) 1 NC_008253.1 membrane transport protein 4081106 4188978 ECP_3914 Escherichia coli 536 membrane transport protein YP_671786.1 4079769 R 362663 CDS YP_671787.1 110644057 4188979 4081273..4081938 1 NC_008253.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4081938 4188979 ECP_3915 Escherichia coli 536 6-phosphogluconate phosphatase YP_671787.1 4081273 D 362663 CDS YP_671788.1 110644058 4188980 4082005..4082478 1 NC_008253.1 might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4082478 4188980 ECP_3916 Escherichia coli 536 inner membrane protein YP_671788.1 4082005 D 362663 CDS YP_671789.1 110644059 4188981 complement(4082560..4083282) 1 NC_008253.1 6-phosphogluconolactonase 4083282 4188981 ECP_3917 Escherichia coli 536 6-phosphogluconolactonase YP_671789.1 4082560 R 362663 CDS YP_671790.1 110644060 4187754 complement(4083297..4084466) 1 NC_008253.1 hypothetical protein 4084466 4187754 ECP_3918 Escherichia coli 536 hypothetical protein YP_671790.1 4083297 R 362663 CDS YP_671791.1 110644061 4187755 complement(4084493..4086109) 1 NC_008253.1 outer membrane protein YieC 4086109 4187755 ECP_3919 Escherichia coli 536 outer membrane protein YieC YP_671791.1 4084493 R 362663 CDS YP_671792.1 110644062 4187756 complement(4086195..4087589) 1 NC_008253.1 6-phospho-beta-glucosidase 4087589 4187756 ECP_3920 Escherichia coli 536 6-phospho-beta-glucosidase YP_671792.1 4086195 R 362663 CDS YP_671793.1 110644063 4187757 complement(4087608..4089482) 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; beta-glucoside-specific PTS system components IIABC 4089482 4187757 ECP_3921 Escherichia coli 536 beta-glucoside-specific PTS system components IIABC YP_671793.1 4087608 R 362663 CDS YP_671794.1 110644064 4187758 complement(4089615..4090451) 1 NC_008253.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4090451 4187758 ECP_3922 Escherichia coli 536 transcriptional antiterminator BglG YP_671794.1 4089615 R 362663 CDS YP_671795.1 110644065 4187759 complement(4090737..4091462) 1 NC_008253.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4091462 4187759 ECP_3923 Escherichia coli 536 transcriptional regulator PhoU YP_671795.1 4090737 R 362663 CDS YP_671796.1 110644066 4187760 complement(4091477..4092250) 1 NC_008253.1 phosphate transporter subunit 4092250 4187760 ECP_3924 Escherichia coli 536 phosphate transporter subunit YP_671796.1 4091477 R 362663 CDS YP_671797.1 110644067 4187761 complement(4092341..4093225) 1 NC_008253.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4093225 pstA 4187761 pstA Escherichia coli 536 phosphate transporter permease subunit PtsA YP_671797.1 4092341 R 362663 CDS YP_671798.1 110644068 4187762 complement(4093231..4094190) 1 NC_008253.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4094190 pstC 4187762 pstC Escherichia coli 536 phosphate transporter permease subunit PstC YP_671798.1 4093231 R 362663 CDS YP_671799.1 110644069 4187763 complement(4094277..4095317) 1 NC_008253.1 phosphate ABC transporter substrate-binding protein 4095317 4187763 ECP_3927 Escherichia coli 536 phosphate ABC transporter substrate-binding protein YP_671799.1 4094277 R 362663 CDS YP_671800.1 110644070 4187764 complement(4095631..4097460) 1 NC_008253.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4097460 4187764 ECP_3928 Escherichia coli 536 glucosamine--fructose-6-phosphate aminotransferase YP_671800.1 4095631 R 362663 CDS YP_671801.1 110644071 4187765 complement(4097621..4098991) 1 NC_008253.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4098991 glmU 4187765 glmU Escherichia coli 536 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_671801.1 4097621 R 362663 CDS YP_671802.1 110644072 4187766 complement(4099342..4099761) 1 NC_008253.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4099761 atpC 4187766 atpC Escherichia coli 536 ATP synthase F0F1 subunit epsilon YP_671802.1 4099342 R 362663 CDS YP_671803.1 110644073 4187767 complement(4099782..4101164) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4101164 4187767 ECP_3931 Escherichia coli 536 ATP synthase F0F1 subunit beta YP_671803.1 4099782 R 362663 CDS YP_671804.1 110644074 4187768 complement(4101191..4102054) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4102054 4187768 ECP_3932 Escherichia coli 536 ATP synthase F0F1 subunit gamma YP_671804.1 4101191 R 362663 CDS YP_671805.1 110644075 4187769 complement(4102105..4103646) 1 NC_008253.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4103646 4187769 ECP_3933 Escherichia coli 536 ATP synthase F0F1 subunit alpha YP_671805.1 4102105 R 362663 CDS YP_671806.1 110644076 4187770 complement(4103659..4104192) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4104192 4187770 ECP_3934 Escherichia coli 536 ATP synthase F0F1 subunit delta YP_671806.1 4103659 R 362663 CDS YP_671807.1 110644077 4187771 complement(4104207..4104677) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4104677 4187771 ECP_3935 Escherichia coli 536 ATP synthase F0F1 subunit B YP_671807.1 4104207 R 362663 CDS YP_671808.1 110644078 4187772 complement(4104739..4104978) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4104978 4187772 ECP_3936 Escherichia coli 536 ATP synthase F0F1 subunit C YP_671808.1 4104739 R 362663 CDS YP_671809.1 110644079 4189316 complement(4105025..4105840) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4105840 4189316 ECP_3937 Escherichia coli 536 ATP synthase F0F1 subunit A YP_671809.1 4105025 R 362663 CDS YP_671810.1 110644080 4189317 complement(4105849..4106241) 1 NC_008253.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4106241 4189317 ECP_3938 Escherichia coli 536 F0F1 ATP synthase subunit I YP_671810.1 4105849 R 362663 CDS YP_671811.1 110644081 4189318 complement(4106846..4107469) 1 NC_008253.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4107469 gidB 4189318 gidB Escherichia coli 536 16S rRNA methyltransferase GidB YP_671811.1 4106846 R 362663 CDS YP_671812.1 110644082 4189319 complement(4107533..4109422) 1 NC_008253.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4109422 4189319 ECP_3940 Escherichia coli 536 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_671812.1 4107533 R 362663 CDS YP_671813.1 110644083 4189320 complement(4109801..4110244) 1 NC_008253.1 initiation of chromosome replication; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4110244 4189320 ECP_3941 Escherichia coli 536 flavodoxin YP_671813.1 4109801 R 362663 CDS YP_671814.1 110644084 4189321 complement(4110334..4110792) 1 NC_008253.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4110792 4189321 ECP_3942 Escherichia coli 536 DNA-binding transcriptional regulator AsnC YP_671814.1 4110334 R 362663 CDS YP_671815.1 110644085 4189322 4110944..4111936 1 NC_008253.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4111936 4189322 ECP_3943 Escherichia coli 536 asparagine synthetase AsnA YP_671815.1 4110944 D 362663 CDS YP_671816.1 110644086 4189323 complement(4111941..4113392) 1 NC_008253.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4113392 yieM 4189323 yieM Escherichia coli 536 hypothetical protein YP_671816.1 4111941 R 362663 CDS YP_671817.1 110644087 4189324 complement(4113386..4114882) 1 NC_008253.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4114882 4189324 ECP_3945 Escherichia coli 536 regulatory ATPase RavA YP_671817.1 4113386 R 362663 CDS YP_671818.1 110644088 4189325 4115105..4116973 1 NC_008253.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4116973 trkD 4189325 trkD Escherichia coli 536 potassium transport protein Kup YP_671818.1 4115105 D 362663 CDS YP_671819.2 229560206 4189326 4117140..4117559 1 NC_008253.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4117559 4189326 ECP_3947 Escherichia coli 536 D-ribose pyranase YP_671819.2 4117140 D 362663 CDS YP_671820.1 110644090 4189327 4117567..4119072 1 NC_008253.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4119072 4189327 ECP_3948 Escherichia coli 536 D-ribose transporter ATP-binding protein YP_671820.1 4117567 D 362663 CDS YP_671821.1 110644091 4189330 4120068..4120958 1 NC_008253.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4120958 4189330 ECP_3951 Escherichia coli 536 D-ribose transporter subunit RbsB YP_671821.1 4120068 D 362663 CDS YP_671822.1 110644092 4189331 4121069..4122013 1 NC_008253.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4122013 4189331 ECP_3952 Escherichia coli 536 ribokinase YP_671822.1 4121069 D 362663 CDS YP_671823.1 110644093 4189332 4122017..4123009 1 NC_008253.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4123009 4189332 ECP_3953 Escherichia coli 536 transcriptional repressor RbsR YP_671823.1 4122017 D 362663 CDS YP_671824.1 110644094 4188605 complement(4122975..4124402) 1 NC_008253.1 transporter 4124402 4188605 ECP_3954 Escherichia coli 536 transporter YP_671824.1 4122975 R 362663 CDS YP_671825.1 110644095 4188606 complement(4124425..4125117) 1 NC_008253.1 GntR family transcriptional regulator 4125117 4188606 ECP_3955 Escherichia coli 536 GntR family transcriptional regulator YP_671825.1 4124425 R 362663 CDS YP_671826.1 110644096 4188610 complement(4130918..4131757) 1 NC_008253.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4131757 4188610 ECP_3959 Escherichia coli 536 transcriptional regulator HdfR YP_671826.1 4130918 R 362663 CDS YP_671827.1 110644097 4188611 4131876..4132214 1 NC_008253.1 hypothetical protein 4132214 4188611 ECP_3960 Escherichia coli 536 hypothetical protein YP_671827.1 4131876 D 362663 CDS YP_671828.1 110644098 4188612 complement(4132239..4133759) 1 NC_008253.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 4133759 4188612 ECP_3961 Escherichia coli 536 ATP-dependent protease YP_671828.1 4132239 R 362663 CDS YP_671829.1 110644099 4188613 4134350..4135996 1 NC_008253.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4135996 4188613 ECP_3962 Escherichia coli 536 acetolactate synthase 2 catalytic subunit YP_671829.1 4134350 D 362663 CDS YP_671830.1 110644100 4188614 4136276..4137205 1 NC_008253.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4137205 4188614 ECP_3963 Escherichia coli 536 branched-chain amino acid aminotransferase YP_671830.1 4136276 D 362663 CDS YP_671831.1 110644101 4188615 4137270..4139120 1 NC_008253.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4139120 4188615 ECP_3964 Escherichia coli 536 dihydroxy-acid dehydratase YP_671831.1 4137270 D 362663 CDS YP_671832.1 110644102 4188616 4139120..4140667 1 NC_008253.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4140667 4188616 ECP_3965 Escherichia coli 536 threonine dehydratase YP_671832.1 4139120 D 362663 CDS YP_671833.1 110644103 4188617 complement(4140664..4141689) 1 NC_008253.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4141689 4188617 ECP_3966 Escherichia coli 536 DNA-binding transcriptional regulator IlvY YP_671833.1 4140664 R 362663 CDS YP_671834.1 110644104 4188618 4141704..4143179 1 NC_008253.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4143179 4188618 ECP_3967 Escherichia coli 536 ketol-acid reductoisomerase YP_671834.1 4141704 D 362663 CDS YP_671835.1 110644105 4188619 complement(4143225..4143506) 1 NC_008253.1 peptidyl-prolyl cis-trans isomerase C 4143506 4188619 ECP_3968 Escherichia coli 536 peptidyl-prolyl cis-trans isomerase C YP_671835.1 4143225 R 362663 CDS YP_671836.1 110644106 4188620 4143593..4145614 1 NC_008253.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4145614 4188620 ECP_3969 Escherichia coli 536 ATP-dependent DNA helicase Rep YP_671836.1 4143593 D 362663 CDS YP_671837.1 110644107 4188044 complement(4147282..4148547) 1 NC_008253.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4148547 4188044 ECP_3972 Escherichia coli 536 ATP-dependent RNA helicase RhlB YP_671837.1 4147282 R 362663 CDS YP_671838.1 110644108 4188045 4148573..4149007 1 NC_008253.1 thioredoxin 4149007 trxA 4188045 trxA Escherichia coli 536 thioredoxin YP_671838.1 4148573 D 362663 CDS YP_671839.1 110644109 4188046 4149262..4150593 1 NC_008253.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4150593 rho 4188046 rho Escherichia coli 536 transcription termination factor Rho YP_671839.1 4149262 D 362663 CDS YP_671840.1 110644110 4188047 4150833..4151936 1 NC_008253.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 4151936 4188047 ECP_3975 Escherichia coli 536 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_671840.1 4150833 D 362663 CDS YP_671841.1 110644111 4188048 4151948..4152994 1 NC_008253.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4152994 4188048 ECP_3976 Escherichia coli 536 lipopolysaccharide biosynthesis protein WzzE YP_671841.1 4151948 D 362663 CDS YP_671842.1 110644112 4188049 4153050..4154180 1 NC_008253.1 UDP-N-acetylglucosamine 2-epimerase 4154180 4188049 ECP_3977 Escherichia coli 536 UDP-N-acetylglucosamine 2-epimerase YP_671842.1 4153050 D 362663 CDS YP_671843.1 110644113 4188050 4154415..4155440 1 NC_008253.1 UDP-N-acetyl-D-mannosamine dehydrogenase 4155440 4188050 ECP_3978 Escherichia coli 536 UDP-N-acetyl-D-mannosamine dehydrogenase YP_671843.1 4154415 D 362663 CDS YP_671844.1 110644114 4188051 4155440..4156507 1 NC_008253.1 dTDP-glucose 4,6-dehydratase 4156507 4188051 ECP_3979 Escherichia coli 536 dTDP-glucose 4,6-dehydratase YP_671844.1 4155440 D 362663 CDS YP_671845.1 110644115 4188052 4156526..4157407 1 NC_008253.1 glucose-1-phosphate thymidylyltransferase 4157407 4188052 ECP_3980 Escherichia coli 536 glucose-1-phosphate thymidylyltransferase YP_671845.1 4156526 D 362663 CDS YP_671846.1 110644116 4188053 4157385..4158059 1 NC_008253.1 TDP-fucosamine acetyltransferase 4158059 4188053 ECP_3981 Escherichia coli 536 TDP-fucosamine acetyltransferase YP_671846.1 4157385 D 362663 CDS YP_671847.1 110644117 4188054 4158064..4159194 1 NC_008253.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4159194 4188054 ECP_3982 Escherichia coli 536 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_671847.1 4158064 D 362663 CDS YP_671848.1 110644118 4188055 4159196..4160446 1 NC_008253.1 lipopolysaccharide biosynthesis protein WzxE 4160446 4188055 ECP_3983 Escherichia coli 536 lipopolysaccharide biosynthesis protein WzxE YP_671848.1 4159196 D 362663 CDS YP_671849.1 110644119 4188056 4160443..4161522 1 NC_008253.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4161522 4188056 ECP_3984 Escherichia coli 536 4-alpha-L-fucosyltransferase YP_671849.1 4160443 D 362663 CDS YP_671850.1 110644120 4188057 4161519..4162871 1 NC_008253.1 enterobacterial common antigen polymerase; common antigen polymerase 4162871 4188057 ECP_3985 Escherichia coli 536 common antigen polymerase YP_671850.1 4161519 D 362663 CDS YP_671851.1 110644121 4188058 4162874..4163614 1 NC_008253.1 UDP-N-acetyl-D-mannosaminuronic acid transferase 4163614 4188058 ECP_3986 Escherichia coli 536 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_671851.1 4162874 D 362663 CDS YP_671852.1 110644122 4190963 4163805..4165190 1 NC_008253.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 4165190 4190963 ECP_3987 Escherichia coli 536 transporter YP_671852.1 4163805 D 362663 CDS YP_671853.1 110644123 4190968 4165876..4167111 1 NC_008253.1 arylsulfatase regulatory protein 4167111 4190968 ECP_3992 Escherichia coli 536 arylsulfatase regulatory protein YP_671853.1 4165876 D 362663 CDS YP_671854.1 110644124 4190969 complement(4167202..4168857) 1 NC_008253.1 arylsulfatase 4168857 4190969 ECP_3993 Escherichia coli 536 arylsulfatase YP_671854.1 4167202 R 362663 CDS YP_671855.1 110644125 4190970 complement(4169536..4170732) 1 NC_008253.1 protoheme IX biogenesis protein 4170732 4190970 ECP_3994 Escherichia coli 536 protoheme IX biogenesis protein YP_671855.1 4169536 R 362663 CDS YP_671856.1 110644126 4190971 complement(4170735..4171934) 1 NC_008253.1 uroporphyrinogen III C-methyltransferase 4171934 4190971 ECP_3995 Escherichia coli 536 uroporphyrinogen III C-methyltransferase YP_671856.1 4170735 R 362663 CDS YP_671857.1 110644127 4190972 complement(4171956..4172696) 1 NC_008253.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4172696 hemD 4190972 hemD Escherichia coli 536 uroporphyrinogen-III synthase YP_671857.1 4171956 R 362663 CDS YP_671858.1 110644128 4190973 complement(4172693..4173655) 1 NC_008253.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4173655 hemC 4190973 hemC Escherichia coli 536 porphobilinogen deaminase YP_671858.1 4172693 R 362663 CDS YP_671859.1 110644129 4190974 complement(4173787..4174116) 1 NC_008253.1 hypothetical protein 4174116 4190974 ECP_3998 Escherichia coli 536 hypothetical protein YP_671859.1 4173787 R 362663 CDS YP_671860.2 229560205 4190975 4174021..4176567 1 NC_008253.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4176567 cyaA 4190975 cyaA Escherichia coli 536 adenylate cyclase YP_671860.2 4174021 D 362663 CDS YP_671861.1 110644131 4190976 complement(4176607..4176927) 1 NC_008253.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4176927 cyaY 4190976 cyaY Escherichia coli 536 frataxin-like protein YP_671861.1 4176607 R 362663 CDS YP_671862.1 110644132 4190977 complement(4176975..4177208) 1 NC_008253.1 hypothetical protein 4177208 4190977 ECP_4001 Escherichia coli 536 hypothetical protein YP_671862.1 4176975 R 362663 CDS YP_671863.1 110644133 4190780 4177397..4177600 1 NC_008253.1 hypothetical protein 4177600 4190780 ECP_4002 Escherichia coli 536 hypothetical protein YP_671863.1 4177397 D 362663 CDS YP_671864.1 110644134 4190781 4177637..4178461 1 NC_008253.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4178461 dapF 4190781 dapF Escherichia coli 536 diaminopimelate epimerase YP_671864.1 4177637 D 362663 CDS YP_671865.1 110644135 4190782 4178458..4179165 1 NC_008253.1 hypothetical protein 4179165 4190782 ECP_4004 Escherichia coli 536 hypothetical protein YP_671865.1 4178458 D 362663 CDS YP_671866.1 110644136 4190783 4179162..4180058 1 NC_008253.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4180058 xerC 4190783 xerC Escherichia coli 536 site-specific tyrosine recombinase XerC YP_671866.1 4179162 D 362663 CDS YP_671867.1 110644137 4190784 4180058..4180774 1 NC_008253.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4180774 4190784 ECP_4006 Escherichia coli 536 flavin mononucleotide phosphatase YP_671867.1 4180058 D 362663 CDS YP_671868.1 110644138 4190785 4180858..4183020 1 NC_008253.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4183020 uvrD 4190785 uvrD Escherichia coli 536 DNA-dependent helicase II YP_671868.1 4180858 D 362663 CDS YP_671869.1 110644139 4190786 complement(4183065..4183967) 1 NC_008253.1 hypothetical protein 4183967 4190786 ECP_4008 Escherichia coli 536 hypothetical protein YP_671869.1 4183065 R 362663 CDS YP_671870.1 110644140 4190787 complement(4184050..4184814) 1 NC_008253.1 hypothetical protein 4184814 4190787 ECP_4009 Escherichia coli 536 hypothetical protein YP_671870.1 4184050 R 362663 CDS YP_671871.1 110644141 4190788 4185184..4186134 1 NC_008253.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4186134 4190788 ECP_4010 Escherichia coli 536 magnesium/nickel/cobalt transporter CorA YP_671871.1 4185184 D 362663 CDS YP_671872.1 110644142 4190789 complement(4186170..4186667) 1 NC_008253.1 hypothetical protein 4186667 4190789 ECP_4011 Escherichia coli 536 hypothetical protein YP_671872.1 4186170 R 362663 CDS YP_671873.1 110644143 4190790 complement(4186664..4187512) 1 NC_008253.1 hypothetical protein 4187512 4190790 ECP_4012 Escherichia coli 536 hypothetical protein YP_671873.1 4186664 R 362663 CDS YP_671874.1 110644144 4190791 complement(4187822..4188712) 1 NC_008253.1 hypothetical protein 4188712 4190791 ECP_4013 Escherichia coli 536 hypothetical protein YP_671874.1 4187822 R 362663 CDS YP_671875.1 110644145 4190792 complement(4188764..4189231) 1 NC_008253.1 hypothetical protein 4189231 4190792 ECP_4014 Escherichia coli 536 hypothetical protein YP_671875.1 4188764 R 362663 CDS YP_671876.1 110644146 4190793 4189395..4190264 1 NC_008253.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4190264 4190793 ECP_4015 Escherichia coli 536 phospholipase A YP_671876.1 4189395 D 362663 CDS YP_671877.1 110644147 4190794 4190389..4192218 1 NC_008253.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4192218 4190794 ECP_4016 Escherichia coli 536 ATP-dependent DNA helicase RecQ YP_671877.1 4190389 D 362663 CDS YP_671878.1 110644148 4190795 4192282..4192902 1 NC_008253.1 threonine efflux system 4192902 4190795 ECP_4017 Escherichia coli 536 threonine efflux system YP_671878.1 4192282 D 362663 CDS YP_671879.1 110644149 4190796 complement(4192963..4193583) 1 NC_008253.1 homoserine/homoserine lactone efflux protein 4193583 rhtB 4190796 rhtB Escherichia coli 536 homoserine/homoserine lactone efflux protein YP_671879.1 4192963 R 362663 CDS YP_671880.1 110644150 4190797 4193694..4194716 1 NC_008253.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4194716 4190797 ECP_4019 Escherichia coli 536 lysophospholipase L2 YP_671880.1 4193694 D 362663 CDS YP_671881.1 110644151 4190798 4194724..4195524 1 NC_008253.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4195524 4190798 ECP_4020 Escherichia coli 536 sugar phosphatase YP_671881.1 4194724 D 362663 CDS YP_671882.1 110644152 4190799 4195600..4196499 1 NC_008253.1 hypothetical protein 4196499 4190799 ECP_4021 Escherichia coli 536 hypothetical protein YP_671882.1 4195600 D 362663 CDS YP_671883.1 110644153 4188753 complement(4196387..4197340) 1 NC_008253.1 LysR family transcriptional regulator 4197340 4188753 ECP_4022 Escherichia coli 536 LysR family transcriptional regulator YP_671883.1 4196387 R 362663 CDS YP_671884.1 110644154 4188754 4197458..4199719 1 NC_008253.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4199719 4188754 ECP_4023 Escherichia coli 536 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_671884.1 4197458 D 362663 CDS YP_671885.1 110644155 4188755 complement(4199888..4200133) 1 NC_008253.1 hypothetical protein 4200133 4188755 ECP_4024 Escherichia coli 536 hypothetical protein YP_671885.1 4199888 R 362663 CDS YP_671886.1 110644156 4188756 complement(4200208..4200465) 1 NC_008253.1 hypothetical protein 4200465 4188756 ECP_4025 Escherichia coli 536 hypothetical protein YP_671886.1 4200208 R 362663 CDS YP_671887.1 110644157 4188757 complement(4200462..4201595) 1 NC_008253.1 hypothetical protein 4201595 4188757 ECP_4026 Escherichia coli 536 hypothetical protein YP_671887.1 4200462 R 362663 CDS YP_671888.1 110644158 4188758 4202080..4202637 1 NC_008253.1 hypothetical protein 4202637 4188758 ECP_4027 Escherichia coli 536 hypothetical protein YP_671888.1 4202080 D 362663 CDS YP_671889.1 110644159 4188759 4202679..4204187 1 NC_008253.1 PTS system, glucose-specific IIBC component 4204187 4188759 ECP_4028 Escherichia coli 536 PTS system, glucose-specific IIBC component YP_671889.1 4202679 D 362663 CDS YP_671890.1 110644160 4188760 4204238..4206235 1 NC_008253.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4206235 4188760 ECP_4029 Escherichia coli 536 transketolase YP_671890.1 4204238 D 362663 CDS YP_671891.1 110644161 4188761 complement(4206265..4207110) 1 NC_008253.1 transcriptional regulator 4207110 4188761 ECP_4030 Escherichia coli 536 transcriptional regulator YP_671891.1 4206265 R 362663 CDS YP_671892.1 110644162 4188762 complement(4207311..4208216) 1 NC_008253.1 LysR family transcriptional regulator 4208216 4188762 ECP_4031 Escherichia coli 536 LysR family transcriptional regulator YP_671892.1 4207311 R 362663 CDS YP_671893.1 110644163 4188763 complement(4208294..4209517) 1 NC_008253.1 permease 4209517 4188763 ECP_4032 Escherichia coli 536 permease YP_671893.1 4208294 R 362663 CDS YP_671894.1 110644164 4188764 complement(4209543..4209932) 1 NC_008253.1 hypothetical protein 4209932 4188764 ECP_4033 Escherichia coli 536 hypothetical protein YP_671894.1 4209543 R 362663 CDS YP_671895.1 110644165 4188765 complement(4209949..4210905) 1 NC_008253.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4210905 4188765 ECP_4034 Escherichia coli 536 carbamate kinase YP_671895.1 4209949 R 362663 CDS YP_671896.1 110644166 4188766 complement(4210898..4212322) 1 NC_008253.1 hypothetical protein 4212322 4188766 ECP_4035 Escherichia coli 536 hypothetical protein YP_671896.1 4210898 R 362663 CDS YP_671897.1 110644167 4188767 complement(4212319..4213878) 1 NC_008253.1 YahF/FdrA-like protein 4213878 4188767 ECP_4036 Escherichia coli 536 YahF/FdrA-like protein YP_671897.1 4212319 R 362663 CDS YP_671898.1 110644168 4188768 complement(4213973..4214833) 1 NC_008253.1 hypothetical protein 4214833 4188768 ECP_4037 Escherichia coli 536 hypothetical protein YP_671898.1 4213973 R 362663 CDS YP_671899.1 110644169 4188769 complement(4214839..4215507) 1 NC_008253.1 isochorismatase YcdL 4215507 4188769 ECP_4038 Escherichia coli 536 isochorismatase YcdL YP_671899.1 4214839 R 362663 CDS YP_671900.1 110644170 4188770 complement(4215764..4216573) 1 NC_008253.1 carboxymethylenebutenolidase 4216573 4188770 ECP_4039 Escherichia coli 536 carboxymethylenebutenolidase YP_671900.1 4215764 R 362663 CDS YP_671901.1 110644171 4188771 4216835..4217599 1 NC_008253.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4217599 4188771 ECP_4040 Escherichia coli 536 uridine phosphorylase YP_671901.1 4216835 D 362663 CDS YP_671902.1 110644172 4187907 complement(4217634..4219124) 1 NC_008253.1 hypothetical protein 4219124 4187907 ECP_4041 Escherichia coli 536 hypothetical protein YP_671902.1 4217634 R 362663 CDS YP_671903.1 110644173 4187908 complement(4219137..4219643) 1 NC_008253.1 hypothetical protein 4219643 4187908 ECP_4042 Escherichia coli 536 hypothetical protein YP_671903.1 4219137 R 362663 CDS YP_671904.1 110644174 4187909 complement(4219660..4220634) 1 NC_008253.1 hypothetical protein 4220634 4187909 ECP_4043 Escherichia coli 536 hypothetical protein YP_671904.1 4219660 R 362663 CDS YP_671905.1 110644175 4187910 complement(4220659..4221288) 1 NC_008253.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4221288 4187910 ECP_4044 Escherichia coli 536 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_671905.1 4220659 R 362663 CDS YP_671906.1 110644176 4187911 complement(4221278..4222282) 1 NC_008253.1 2-oxo-3-deoxygalactonate kinase 4222282 4187911 ECP_4045 Escherichia coli 536 2-oxo-3-deoxygalactonate kinase YP_671906.1 4221278 R 362663 CDS YP_671907.1 110644177 4187912 complement(4222306..4223073) 1 NC_008253.1 transcriptional regulator 4223073 4187912 ECP_4046 Escherichia coli 536 transcriptional regulator YP_671907.1 4222306 R 362663 CDS YP_671908.1 110644178 4187913 4223290..4224717 1 NC_008253.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4224717 4187913 ECP_4047 Escherichia coli 536 DNA recombination protein RmuC YP_671908.1 4223290 D 362663 CDS YP_671909.1 110644179 4187914 4224812..4225567 1 NC_008253.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4225567 ubiE 4187914 ubiE Escherichia coli 536 ubiquinone/menaquinone biosynthesis methyltransferase YP_671909.1 4224812 D 362663 CDS YP_671910.1 110644180 4187915 4225581..4226186 1 NC_008253.1 hypothetical protein 4226186 4187915 ECP_4049 Escherichia coli 536 hypothetical protein YP_671910.1 4225581 D 362663 CDS YP_671911.1 110644181 4187916 4226183..4227823 1 NC_008253.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4227823 ubiB 4187916 ubiB Escherichia coli 536 ubiquinone biosynthesis protein UbiB YP_671911.1 4226183 D 362663 CDS YP_671912.1 110644182 4187917 4227902..4228171 1 NC_008253.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase A 4228171 tatA 4187917 tatA Escherichia coli 536 twin arginine translocase A YP_671912.1 4227902 D 362663 CDS YP_671913.1 110644183 4187918 4228175..4228690 1 NC_008253.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4228690 4187918 ECP_4052 Escherichia coli 536 sec-independent translocase YP_671913.1 4228175 D 362663 CDS YP_671914.1 110644184 4187919 4228693..4229469 1 NC_008253.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4229469 4187919 ECP_4053 Escherichia coli 536 twin-arginine protein translocation system subunit TatC YP_671914.1 4228693 D 362663 CDS YP_671915.1 110644185 4187920 4229499..4230293 1 NC_008253.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4230293 4187920 ECP_4054 Escherichia coli 536 DNase TatD YP_671915.1 4229499 D 362663 CDS YP_671916.1 110644186 4187921 complement(4230290..4230778) 1 NC_008253.1 transcriptional activator RfaH 4230778 rfaH 4187921 rfaH Escherichia coli 536 transcriptional activator RfaH YP_671916.1 4230290 R 362663 CDS YP_671917.1 110644187 4187922 4230945..4232441 1 NC_008253.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4232441 4187922 ECP_4056 Escherichia coli 536 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_671917.1 4230945 D 362663 CDS YP_671918.1 110644188 4187923 4232487..4233188 1 NC_008253.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4233188 fre 4187923 fre Escherichia coli 536 FMN reductase YP_671918.1 4232487 D 362663 CDS YP_671919.1 110644189 4187924 complement(4233470..4234633) 1 NC_008253.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4234633 fadA 4187924 fadA Escherichia coli 536 3-ketoacyl-CoA thiolase YP_671919.1 4233470 R 362663 CDS YP_671920.1 110644190 4187925 complement(4234643..4236832) 1 NC_008253.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4236832 fadB 4187925 fadB Escherichia coli 536 multifunctional fatty acid oxidation complex subunit alpha YP_671920.1 4234643 R 362663 CDS YP_671921.1 110644191 4187926 4237022..4238353 1 NC_008253.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4238353 4187926 ECP_4060 Escherichia coli 536 proline dipeptidase YP_671921.1 4237022 D 362663 CDS YP_671922.1 110644192 4187700 4238350..4238967 1 NC_008253.1 hypothetical protein 4238967 4187700 ECP_4061 Escherichia coli 536 hypothetical protein YP_671922.1 4238350 D 362663 CDS YP_671923.1 110644193 4187701 4239006..4240457 1 NC_008253.1 potassium transporter 4240457 4187701 ECP_4062 Escherichia coli 536 potassium transporter YP_671923.1 4239006 D 362663 CDS YP_671924.1 110644194 4187702 4240469..4241014 1 NC_008253.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4241014 hemG 4187702 hemG Escherichia coli 536 protoporphyrinogen oxidase YP_671924.1 4240469 D 362663 CDS YP_671925.1 110644195 4187705 complement(4246599..4247126) 1 NC_008253.1 molybdopterin-guanine dinucleotide biosynthesis protein B 4247126 4187705 ECP_4066 Escherichia coli 536 molybdopterin-guanine dinucleotide biosynthesis protein B YP_671925.1 4246599 R 362663 CDS YP_671926.1 110644196 4187706 complement(4247108..4247683) 1 NC_008253.1 Links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein A 4247683 mobA 4187706 mobA Escherichia coli 536 molybdopterin-guanine dinucleotide biosynthesis protein A YP_671926.1 4247108 R 362663 CDS YP_671927.1 110644197 4187707 4247762..4248031 1 NC_008253.1 hypothetical protein 4248031 4187707 ECP_4068 Escherichia coli 536 hypothetical protein YP_671927.1 4247762 D 362663 CDS YP_671928.1 110644198 4187708 4248108..4249094 1 NC_008253.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4249094 4187708 ECP_4069 Escherichia coli 536 serine/threonine protein kinase YP_671928.1 4248108 D 362663 CDS YP_671929.1 110644199 4187709 4249111..4249737 1 NC_008253.1 protein disulfide isomerase I 4249737 4187709 ECP_4070 Escherichia coli 536 protein disulfide isomerase I YP_671929.1 4249111 D 362663 CDS YP_671930.1 110644200 4187710 4249892..4251322 1 NC_008253.1 hypothetical protein 4251322 4187710 ECP_4071 Escherichia coli 536 hypothetical protein YP_671930.1 4249892 D 362663 CDS YP_671931.1 110644201 4187711 complement(4251363..4252295) 1 NC_008253.1 acyltransferase 4252295 4187711 ECP_4072 Escherichia coli 536 acyltransferase YP_671931.1 4251363 R 362663 CDS YP_671932.1 110644202 4187712 complement(4252415..4252600) 1 NC_008253.1 hypothetical protein 4252600 4187712 ECP_4073 Escherichia coli 536 hypothetical protein YP_671932.1 4252415 R 362663 CDS YP_671933.1 110644203 4187713 4252659..4255445 1 NC_008253.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4255445 4187713 ECP_4074 Escherichia coli 536 DNA polymerase I YP_671933.1 4252659 D 362663 CDS YP_671934.1 110644204 4187714 complement(4255827..4256420) 1 NC_008253.1 GTP-binding protein EngB 4256420 4187714 ECP_4075 Escherichia coli 536 GTP-binding protein EngB YP_671934.1 4255827 R 362663 CDS YP_671935.1 110644205 4187715 4257042..4257551 1 NC_008253.1 hypothetical protein 4257551 4187715 ECP_4076 Escherichia coli 536 hypothetical protein YP_671935.1 4257042 D 362663 CDS YP_671936.1 110644206 4187716 4257740..4259113 1 NC_008253.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4259113 4187716 ECP_4077 Escherichia coli 536 coproporphyrinogen III oxidase YP_671936.1 4257740 D 362663 CDS YP_671937.1 110644207 4187206 complement(4259346..4259456) 1 NC_008253.1 hypothetical protein 4259456 4187206 ECP_4078 Escherichia coli 536 hypothetical protein YP_671937.1 4259346 R 362663 CDS YP_671938.1 110644208 4187207 complement(4259568..4260977) 1 NC_008253.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4260977 glnG 4187207 glnG Escherichia coli 536 nitrogen regulation protein NR(I) YP_671938.1 4259568 R 362663 CDS YP_671939.1 110644209 4187208 complement(4260989..4262038) 1 NC_008253.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4262038 glnL 4187208 glnL Escherichia coli 536 nitrogen regulation protein NR(II) YP_671939.1 4260989 R 362663 CDS YP_671940.1 110644210 4187209 complement(4262212..4263621) 1 NC_008253.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4263621 glnA 4187209 glnA Escherichia coli 536 glutamine synthetase YP_671940.1 4262212 R 362663 CDS YP_671941.1 110644211 4187210 4263994..4265817 1 NC_008253.1 GTP-binding protein 4265817 4187210 ECP_4082 Escherichia coli 536 GTP-binding protein YP_671941.1 4263994 D 362663 CDS YP_671942.1 110644212 4187211 4266034..4266744 1 NC_008253.1 transcriptional regulator YihL 4266744 4187211 ECP_4083 Escherichia coli 536 transcriptional regulator YihL YP_671942.1 4266034 D 362663 CDS YP_671943.1 110644213 4187212 4266752..4267732 1 NC_008253.1 hypothetical protein 4267732 4187212 ECP_4084 Escherichia coli 536 hypothetical protein YP_671943.1 4266752 D 362663 CDS YP_671944.1 110644214 4187213 4267834..4269099 1 NC_008253.1 membrane protein YihN 4269099 4187213 ECP_4085 Escherichia coli 536 membrane protein YihN YP_671944.1 4267834 D 362663 CDS YP_671945.1 110644215 4187214 complement(4269159..4269947) 1 NC_008253.1 transcriptional regulator YihW 4269947 4187214 ECP_4086 Escherichia coli 536 transcriptional regulator YihW YP_671945.1 4269159 R 362663 CDS YP_671946.1 110644216 4187215 complement(4269987..4270883) 1 NC_008253.1 sugar kinase 4270883 4187215 ECP_4087 Escherichia coli 536 sugar kinase YP_671946.1 4269987 R 362663 CDS YP_671947.1 110644217 4187216 4271056..4271934 1 NC_008253.1 oxidoreductase YihU 4271934 4187216 ECP_4088 Escherichia coli 536 oxidoreductase YihU YP_671947.1 4271056 D 362663 CDS YP_671948.1 110644218 4187217 4271959..4272846 1 NC_008253.1 hypothetical protein 4272846 4187217 ECP_4089 Escherichia coli 536 hypothetical protein YP_671948.1 4271959 D 362663 CDS YP_671949.1 110644219 4187218 4272879..4273889 1 NC_008253.1 dehydrogenase 4273889 4187218 ECP_4090 Escherichia coli 536 dehydrogenase YP_671949.1 4272879 D 362663 CDS YP_671950.1 110644220 4187219 4273959..4275392 1 NC_008253.1 hypothetical protein 4275392 4187219 ECP_4091 Escherichia coli 536 hypothetical protein YP_671950.1 4273959 D 362663 CDS YP_671951.1 110644221 4187220 4275491..4276840 1 NC_008253.1 transmembrane transport protein 4276840 4187220 ECP_4092 Escherichia coli 536 transmembrane transport protein YP_671951.1 4275491 D 362663 CDS YP_671952.1 110644222 4187221 4276830..4277717 1 NC_008253.1 aldose-1-epimerase 4277717 4187221 ECP_4093 Escherichia coli 536 aldose-1-epimerase YP_671952.1 4276830 D 362663 CDS YP_671953.1 110644223 4187222 4277858..4278457 1 NC_008253.1 phosphatase 4278457 4187222 ECP_4094 Escherichia coli 536 phosphatase YP_671953.1 4277858 D 362663 CDS YP_671954.1 110644224 4187223 4278451..4279323 1 NC_008253.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4279323 rbn 4187223 rbn Escherichia coli 536 ribonuclease BN YP_671954.1 4278451 D 362663 CDS YP_671955.1 110644225 4187224 4279320..4279757 1 NC_008253.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4279757 4187224 ECP_4096 Escherichia coli 536 D-tyrosyl-tRNA(Tyr) deacylase YP_671955.1 4279320 D 362663 CDS YP_671956.1 110644226 4187225 4279754..4280743 1 NC_008253.1 acetyltransferase 4280743 4187225 ECP_4097 Escherichia coli 536 acetyltransferase YP_671956.1 4279754 D 362663 CDS YP_671957.1 110644227 4189718 complement(4280807..4281727) 1 NC_008253.1 acetyl-hydrolase 4281727 4189718 ECP_4098 Escherichia coli 536 acetyl-hydrolase YP_671957.1 4280807 R 362663 CDS YP_671958.1 110644228 4189719 4282094..4282255 1 NC_008253.1 hypothetical protein 4282255 4189719 ECP_4099 Escherichia coli 536 hypothetical protein YP_671958.1 4282094 D 362663 CDS YP_671959.1 110644229 4189720 4282256..4282546 1 NC_008253.1 hypothetical protein 4282546 4189720 ECP_4100 Escherichia coli 536 hypothetical protein YP_671959.1 4282256 D 362663 CDS YP_671960.1 110644230 4189721 complement(4282954..4283121) 1 NC_008253.1 hypothetical protein 4283121 4189721 ECP_4101 Escherichia coli 536 hypothetical protein YP_671960.1 4282954 R 362663 CDS YP_671961.1 110644231 4189722 4283151..4283369 1 NC_008253.1 hypothetical protein 4283369 4189722 ECP_4102 Escherichia coli 536 hypothetical protein YP_671961.1 4283151 D 362663 CDS YP_671962.1 110644232 4189723 complement(4283584..4284513) 1 NC_008253.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4284513 4189723 ECP_4103 Escherichia coli 536 formate dehydrogenase accessory protein FdhE YP_671962.1 4283584 R 362663 CDS YP_671963.1 110644233 4189724 complement(4284510..4285145) 1 NC_008253.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4285145 4189724 ECP_4104 Escherichia coli 536 formate dehydrogenase-O subunit gamma YP_671963.1 4284510 R 362663 CDS YP_671964.1 110644234 4189725 complement(4285142..4286044) 1 NC_008253.1 formate dehydrogenase-O, iron-sulfur subunit 4286044 4189725 ECP_4105 Escherichia coli 536 formate dehydrogenase-O, iron-sulfur subunit YP_671964.1 4285142 R 362663 CDS YP_671965.1 110644235 4189728 4289301..4290134 1 NC_008253.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4290134 4189728 ECP_4108 Escherichia coli 536 formate dehydrogenase accessory protein YP_671965.1 4289301 D 362663 CDS YP_671966.1 110644236 4189729 4290184..4290846 1 NC_008253.1 hypothetical protein 4290846 4189729 ECP_4109 Escherichia coli 536 hypothetical protein YP_671966.1 4290184 D 362663 CDS YP_671967.1 110644237 4189730 4291267..4292661 1 NC_008253.1 hypothetical protein 4292661 4189730 ECP_4110 Escherichia coli 536 hypothetical protein YP_671967.1 4291267 D 362663 CDS YP_671968.1 110644238 4189731 complement(4292702..4293016) 1 NC_008253.1 hypothetical protein 4293016 4189731 ECP_4111 Escherichia coli 536 hypothetical protein YP_671968.1 4292702 R 362663 CDS YP_671969.1 110644239 4189732 complement(4293026..4293850) 1 NC_008253.1 rhamnulose-1-phosphate aldolase 4293850 4189732 ECP_4112 Escherichia coli 536 rhamnulose-1-phosphate aldolase YP_671969.1 4293026 R 362663 CDS YP_671970.1 110644240 4189733 complement(4294025..4295284) 1 NC_008253.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4295284 4189733 ECP_4113 Escherichia coli 536 L-rhamnose isomerase YP_671970.1 4294025 R 362663 CDS YP_671971.1 110644241 4189734 complement(4295281..4296750) 1 NC_008253.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4296750 rhaB 4189734 rhaB Escherichia coli 536 rhamnulokinase YP_671971.1 4295281 R 362663 CDS YP_671972.1 110644242 4191054 4297038..4297874 1 NC_008253.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4297874 4191054 ECP_4115 Escherichia coli 536 transcriptional activator RhaS YP_671972.1 4297038 D 362663 CDS YP_671973.1 110644243 4191055 4297858..4298796 1 NC_008253.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4298796 4191055 ECP_4116 Escherichia coli 536 transcriptional activator RhaR YP_671973.1 4297858 D 362663 CDS YP_671974.1 110644244 4191056 complement(4298793..4299827) 1 NC_008253.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4299827 4191056 ECP_4117 Escherichia coli 536 rhamnose-proton symporter YP_671974.1 4298793 R 362663 CDS YP_671975.1 110644245 4191057 4300113..4300733 1 NC_008253.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4300733 4191057 ECP_4118 Escherichia coli 536 superoxide dismutase YP_671975.1 4300113 D 362663 CDS YP_671976.1 110644246 4191058 4300993..4301976 1 NC_008253.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4301976 4191058 ECP_4119 Escherichia coli 536 2-keto-3-deoxygluconate permease YP_671976.1 4300993 D 362663 CDS YP_671977.1 110644247 4191059 4302125..4302799 1 NC_008253.1 hypothetical protein 4302799 4191059 ECP_4120 Escherichia coli 536 hypothetical protein YP_671977.1 4302125 D 362663 CDS YP_671978.1 110644248 4191060 complement(4302971..4304344) 1 NC_008253.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4304344 cpxA 4191060 cpxA Escherichia coli 536 two-component sensor protein YP_671978.1 4302971 R 362663 CDS YP_671979.1 110644249 4191061 complement(4304341..4305039) 1 NC_008253.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4305039 4191061 ECP_4122 Escherichia coli 536 DNA-binding transcriptional regulator CpxR YP_671979.1 4304341 R 362663 CDS YP_671980.1 110644250 4191062 4305189..4305689 1 NC_008253.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4305689 cpxP 4191062 cpxP Escherichia coli 536 repressor CpxP YP_671980.1 4305189 D 362663 CDS YP_671981.1 110644251 4191063 4305838..4306740 1 NC_008253.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4306740 fieF 4191063 fieF Escherichia coli 536 ferrous iron efflux protein F YP_671981.1 4305838 D 362663 CDS YP_671982.1 110644252 4191064 4306921..4307883 1 NC_008253.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4307883 4191064 ECP_4125 Escherichia coli 536 6-phosphofructokinase YP_671982.1 4306921 D 362663 CDS YP_671983.1 110644253 4191065 4308203..4309192 1 NC_008253.1 sulfate transporter subunit 4309192 4191065 ECP_4126 Escherichia coli 536 sulfate transporter subunit YP_671983.1 4308203 D 362663 CDS YP_671984.1 110644254 4191066 4309329..4310054 1 NC_008253.1 CDP-diacylglycerol pyrophosphatase 4310054 4191066 ECP_4127 Escherichia coli 536 CDP-diacylglycerol pyrophosphatase YP_671984.1 4309329 D 362663 CDS YP_671985.1 110644255 4191067 complement(4310109..4310876) 1 NC_008253.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4310876 tpiA 4191067 tpiA Escherichia coli 536 triosephosphate isomerase YP_671985.1 4310109 R 362663 CDS YP_671986.1 110644256 4191068 complement(4310984..4311583) 1 NC_008253.1 hypothetical protein 4311583 4191068 ECP_4129 Escherichia coli 536 hypothetical protein YP_671986.1 4310984 R 362663 CDS YP_671987.1 110644257 4191069 4311684..4312124 1 NC_008253.1 hypothetical protein 4312124 4191069 ECP_4130 Escherichia coli 536 hypothetical protein YP_671987.1 4311684 D 362663 CDS YP_671988.1 110644258 4191070 4312335..4312634 1 NC_008253.1 hypothetical protein 4312634 4191070 ECP_4131 Escherichia coli 536 hypothetical protein YP_671988.1 4312335 D 362663 CDS YP_671989.1 110644259 4191071 4312661..4313089 1 NC_008253.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4313089 4191071 ECP_4132 Escherichia coli 536 universal stress protein UspD YP_671989.1 4312661 D 362663 CDS YP_671990.1 110644260 4191072 complement(4313094..4313840) 1 NC_008253.1 ferredoxin-NADP reductase 4313840 4191072 ECP_4133 Escherichia coli 536 ferredoxin-NADP reductase YP_671990.1 4313094 R 362663 CDS YP_671991.1 110644261 4188316 complement(4313937..4314947) 1 NC_008253.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4314947 glpX 4188316 glpX Escherichia coli 536 fructose 1,6-bisphosphatase II YP_671991.1 4313937 R 362663 CDS YP_671992.1 110644262 4188317 complement(4315118..4316626) 1 NC_008253.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4316626 glpK 4188317 glpK Escherichia coli 536 glycerol kinase YP_671992.1 4315118 R 362663 CDS YP_671993.1 110644263 4188318 complement(4316649..4317494) 1 NC_008253.1 glycerol uptake facilitator protein 4317494 4188318 ECP_4136 Escherichia coli 536 glycerol uptake facilitator protein YP_671993.1 4316649 R 362663 CDS YP_671994.1 110644264 4188319 4317925..4318164 1 NC_008253.1 hypothetical protein 4318164 4188319 ECP_4137 Escherichia coli 536 hypothetical protein YP_671994.1 4317925 D 362663 CDS YP_671995.1 110644265 4188320 complement(4318249..4318734) 1 NC_008253.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4318734 4188320 ECP_4138 Escherichia coli 536 ribonuclease activity regulator protein RraA YP_671995.1 4318249 R 362663 CDS YP_671996.1 110644266 4188321 complement(4318827..4319753) 1 NC_008253.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4319753 4188321 ECP_4139 Escherichia coli 536 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_671996.1 4318827 R 362663 CDS YP_671997.1 110644267 4188322 complement(4319820..4321151) 1 NC_008253.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4321151 hslU 4188322 hslU Escherichia coli 536 ATP-dependent protease ATP-binding subunit HslU YP_671997.1 4319820 R 362663 CDS YP_671998.1 110644268 4188323 complement(4321161..4321691) 1 NC_008253.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4321691 4188323 ECP_4141 Escherichia coli 536 ATP-dependent protease peptidase subunit YP_671998.1 4321161 R 362663 CDS YP_671999.1 110644269 4188324 complement(4321784..4322743) 1 NC_008253.1 cell division protein FtsN 4322743 4188324 ECP_4142 Escherichia coli 536 cell division protein FtsN YP_671999.1 4321784 R 362663 CDS YP_672000.1 110644270 4188325 complement(4322835..4323860) 1 NC_008253.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4323860 4188325 ECP_4143 Escherichia coli 536 DNA-binding transcriptional regulator CytR YP_672000.1 4322835 R 362663 CDS YP_672001.1 110644271 4188326 complement(4324016..4326214) 1 NC_008253.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4326214 4188326 ECP_4144 Escherichia coli 536 primosome assembly protein PriA YP_672001.1 4324016 R 362663 CDS YP_672002.1 110644272 4188327 4326417..4326629 1 NC_008253.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4326629 rpmE 4188327 rpmE Escherichia coli 536 50S ribosomal protein L31 YP_672002.1 4326417 D 362663 CDS YP_672003.1 110644273 4188328 complement(4326690..4327298) 1 NC_008253.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4327298 4188328 ECP_4146 Escherichia coli 536 peptidoglycan peptidase YP_672003.1 4326690 R 362663 CDS YP_672004.1 110644274 4188329 complement(4327358..4327675) 1 NC_008253.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4327675 4188329 ECP_4147 Escherichia coli 536 transcriptional repressor protein MetJ YP_672004.1 4327358 R 362663 CDS YP_672005.1 110644275 4188330 4327952..4329112 1 NC_008253.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4329112 4188330 ECP_4148 Escherichia coli 536 cystathionine gamma-synthase YP_672005.1 4327952 D 362663 CDS YP_672006.1 110644276 4188331 4329115..4331547 1 NC_008253.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4331547 metL 4188331 metL Escherichia coli 536 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_672006.1 4329115 D 362663 CDS YP_672007.1 110644277 4188332 complement(4331765..4332523) 1 NC_008253.1 nucleoside-specific channel-forming protein tsx 4332523 4188332 ECP_4150 Escherichia coli 536 nucleoside-specific channel-forming protein tsx YP_672007.1 4331765 R 362663 CDS YP_672008.1 110644278 4188333 complement(4332702..4334321) 1 NC_008253.1 5'-nucleotidase 4334321 4188333 ECP_4151 Escherichia coli 536 5'-nucleotidase YP_672008.1 4332702 R 362663 CDS YP_672009.1 110644279 4188334 complement(4334362..4335912) 1 NC_008253.1 5'-nucleotidase 4335912 4188334 ECP_4152 Escherichia coli 536 5'-nucleotidase YP_672009.1 4334362 R 362663 CDS YP_672010.1 110644280 4188335 complement(4336145..4337269) 1 NC_008253.1 hypothetical protein 4337269 4188335 ECP_4153 Escherichia coli 536 hypothetical protein YP_672010.1 4336145 R 362663 CDS YP_672011.1 110644281 4189182 4337402..4338955 1 NC_008253.1 5'-nucleotidase 4338955 4189182 ECP_4154 Escherichia coli 536 5'-nucleotidase YP_672011.1 4337402 D 362663 CDS YP_672012.1 110644282 4189183 4339337..4340227 1 NC_008253.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4340227 metF 4189183 metF Escherichia coli 536 5,10-methylenetetrahydrofolate reductase YP_672012.1 4339337 D 362663 CDS YP_672013.1 110644283 4189184 4340556..4342736 1 NC_008253.1 peroxidase/catalase HPI 4342736 4189184 ECP_4156 Escherichia coli 536 peroxidase/catalase HPI YP_672013.1 4340556 D 362663 CDS YP_672014.1 110644284 4189185 4342764..4343735 1 NC_008253.1 transporter 4343735 4189185 ECP_4157 Escherichia coli 536 transporter YP_672014.1 4342764 D 362663 CDS YP_672015.1 110644285 4189186 complement(4343762..4344379) 1 NC_008253.1 hypothetical protein 4344379 4189186 ECP_4158 Escherichia coli 536 hypothetical protein YP_672015.1 4343762 R 362663 CDS YP_672016.1 110644286 4189187 complement(4344655..4345758) 1 NC_008253.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4345758 gldA 4189187 gldA Escherichia coli 536 glycerol dehydrogenase YP_672016.1 4344655 R 362663 CDS YP_672017.1 110644287 4189188 complement(4345769..4346431) 1 NC_008253.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4346431 4189188 ECP_4160 Escherichia coli 536 fructose-6-phosphate aldolase YP_672017.1 4345769 R 362663 CDS YP_672018.1 110644288 4189189 complement(4346443..4348944) 1 NC_008253.1 phosphoenolpyruvate-protein phosphotransferase PtsA 4348944 4189189 ECP_4161 Escherichia coli 536 phosphoenolpyruvate-protein phosphotransferase PtsA YP_672018.1 4346443 R 362663 CDS YP_672019.1 110644289 4189190 4349253..4350332 1 NC_008253.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4350332 4189190 ECP_4162 Escherichia coli 536 fructose-like permease EIIC subunit 2 YP_672019.1 4349253 D 362663 CDS YP_672020.1 110644290 4189191 4350347..4350667 1 NC_008253.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; fructose-like phosphotransferase EIIB subunit 2 4350667 4189191 ECP_4163 Escherichia coli 536 fructose-like phosphotransferase EIIB subunit 2 YP_672020.1 4350347 D 362663 CDS YP_672021.1 110644291 4189192 4350718..4353015 1 NC_008253.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4353015 pflD 4189192 pflD Escherichia coli 536 formate acetyltransferase 2 YP_672021.1 4350718 D 362663 CDS YP_672022.1 110644292 4189193 4352981..4353859 1 NC_008253.1 pyruvate formate lyase II activase 4353859 4189193 ECP_4165 Escherichia coli 536 pyruvate formate lyase II activase YP_672022.1 4352981 D 362663 CDS YP_672023.1 110644293 4189194 4353861..4354202 1 NC_008253.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4354202 4189194 ECP_4166 Escherichia coli 536 fructose-like phosphotransferase EIIB subunit 3 YP_672023.1 4353861 D 362663 CDS YP_672024.1 110644294 4189195 complement(4354189..4355040) 1 NC_008253.1 transcriptional regulator YijO 4355040 4189195 ECP_4167 Escherichia coli 536 transcriptional regulator YijO YP_672024.1 4354189 R 362663 CDS YP_672025.1 110644295 4189196 complement(4355266..4356999) 1 NC_008253.1 hypothetical protein 4356999 4189196 ECP_4168 Escherichia coli 536 hypothetical protein YP_672025.1 4355266 R 362663 CDS YP_672026.1 110644296 4189197 complement(4357182..4359833) 1 NC_008253.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4359833 4189197 ECP_4169 Escherichia coli 536 phosphoenolpyruvate carboxylase YP_672026.1 4357182 R 362663 CDS YP_672027.1 110644297 4189198 complement(4360135..4361286) 1 NC_008253.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4361286 4189198 ECP_4170 Escherichia coli 536 acetylornithine deacetylase YP_672027.1 4360135 R 362663 CDS YP_672028.1 110644298 4189199 4361440..4362444 1 NC_008253.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4362444 argC 4189199 argC Escherichia coli 536 N-acetyl-gamma-glutamyl-phosphate reductase YP_672028.1 4361440 D 362663 CDS YP_672029.1 110644299 4189200 4362455..4363228 1 NC_008253.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4363228 4189200 ECP_4172 Escherichia coli 536 acetylglutamate kinase YP_672029.1 4362455 D 362663 CDS YP_672030.1 110644300 4189201 4363289..4364662 1 NC_008253.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4364662 4189201 ECP_4173 Escherichia coli 536 argininosuccinate lyase YP_672030.1 4363289 D 362663 CDS YP_672031.1 110644301 4189202 4365100..4366374 1 NC_008253.1 starvation sensing protein RspA 4366374 4189202 ECP_4174 Escherichia coli 536 starvation sensing protein RspA YP_672031.1 4365100 D 362663 CDS YP_672032.1 110644302 4189203 4366441..4367724 1 NC_008253.1 transporter 4367724 4189203 ECP_4175 Escherichia coli 536 transporter YP_672032.1 4366441 D 362663 CDS YP_672033.1 110644303 4189204 4367976..4368893 1 NC_008253.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4368893 4189204 ECP_4176 Escherichia coli 536 DNA-binding transcriptional regulator OxyR YP_672033.1 4367976 D 362663 CDS YP_672034.1 110644304 4189205 complement(4368876..4370276) 1 NC_008253.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4370276 4189205 ECP_4177 Escherichia coli 536 soluble pyridine nucleotide transhydrogenase YP_672034.1 4368876 R 362663 CDS YP_672035.1 110644305 4189206 4370606..4371772 1 NC_008253.1 hippuricase; hippurate hydrolase 4371772 4189206 ECP_4178 Escherichia coli 536 hippurate hydrolase YP_672035.1 4370606 D 362663 CDS YP_672036.1 110644306 4189207 4371815..4373131 1 NC_008253.1 transporter transmembrane protein 4373131 4189207 ECP_4179 Escherichia coli 536 transporter transmembrane protein YP_672036.1 4371815 D 362663 CDS YP_672037.1 110644307 4189208 4373181..4373885 1 NC_008253.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4373885 4189208 ECP_4180 Escherichia coli 536 DNA-binding transcriptional repressor FabR YP_672037.1 4373181 D 362663 CDS YP_672038.1 110644308 4189209 4373885..4374244 1 NC_008253.1 hypothetical protein 4374244 4189209 ECP_4181 Escherichia coli 536 hypothetical protein YP_672038.1 4373885 D 362663 CDS YP_672039.1 110644309 4189210 complement(4374284..4375384) 1 NC_008253.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4375384 4189210 ECP_4182 Escherichia coli 536 tRNA (uracil-5-)-methyltransferase YP_672039.1 4374284 R 362663 CDS YP_672040.2 229560204 4189211 4375753..4377597 1 NC_008253.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4377597 btuB 4189211 btuB Escherichia coli 536 vitamin B12/cobalamin outer membrane transporter YP_672040.2 4375753 D 362663 CDS YP_672041.2 162138273 4189212 4377542..4378399 1 NC_008253.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4378399 4189212 ECP_4184 Escherichia coli 536 glutamate racemase YP_672041.2 4377542 D 362663 CDS YP_672042.1 110644312 4189214 4384015..4385043 1 NC_008253.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4385043 murB 4189214 murB Escherichia coli 536 UDP-N-acetylenolpyruvoylglucosamine reductase YP_672042.1 4384015 D 362663 CDS YP_672043.1 110644313 4189215 4385040..4386005 1 NC_008253.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4386005 4189215 ECP_4187 Escherichia coli 536 biotin--protein ligase YP_672043.1 4385040 D 362663 CDS YP_672044.1 110644314 4189216 complement(4386034..4387005) 1 NC_008253.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4387005 4189216 ECP_4188 Escherichia coli 536 pantothenate kinase YP_672044.1 4386034 R 362663 CDS YP_672045.1 110644315 4188246 4387902..4389086 1 NC_008253.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4389086 4188246 ECP_4193 Escherichia coli 536 elongation factor Tu YP_672045.1 4387902 D 362663 CDS YP_672046.1 110644316 4188247 4389316..4389699 1 NC_008253.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4389699 secE 4188247 secE Escherichia coli 536 preprotein translocase subunit SecE YP_672046.1 4389316 D 362663 CDS YP_672047.1 110644317 4188248 4389701..4390246 1 NC_008253.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4390246 nusG 4188248 nusG Escherichia coli 536 transcription antitermination protein NusG YP_672047.1 4389701 D 362663 CDS YP_672048.1 110644318 4188249 4390405..4390833 1 NC_008253.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4390833 rplK 4188249 rplK Escherichia coli 536 50S ribosomal protein L11 YP_672048.1 4390405 D 362663 CDS YP_672049.1 110644319 4188250 4390837..4391541 1 NC_008253.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4391541 rplA 4188250 rplA Escherichia coli 536 50S ribosomal protein L1 YP_672049.1 4390837 D 362663 CDS YP_672050.1 110644320 4188251 4391833..4392330 1 NC_008253.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4392330 rplJ 4188251 rplJ Escherichia coli 536 50S ribosomal protein L10 YP_672050.1 4391833 D 362663 CDS YP_672051.1 110644321 4188252 4392397..4392762 1 NC_008253.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4392762 rplL 4188252 rplL Escherichia coli 536 50S ribosomal protein L7/L12 YP_672051.1 4392397 D 362663 CDS YP_672052.1 110644322 4188253 4393082..4397110 1 NC_008253.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4397110 rpoB 4188253 rpoB Escherichia coli 536 DNA-directed RNA polymerase subunit beta YP_672052.1 4393082 D 362663 CDS YP_672053.1 110644323 4188254 4397187..4401410 1 NC_008253.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4401410 4188254 ECP_4201 Escherichia coli 536 DNA-directed RNA polymerase subunit beta' YP_672053.1 4397187 D 362663 CDS YP_672054.1 110644324 4188255 complement(4401652..4402785) 1 NC_008253.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4402785 thiH 4188255 thiH Escherichia coli 536 thiamine biosynthesis protein ThiH YP_672054.1 4401652 R 362663 CDS YP_672055.1 110644325 4188256 complement(4402782..4403552) 1 NC_008253.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4403552 thiG 4188256 thiG Escherichia coli 536 thiazole synthase YP_672055.1 4402782 R 362663 CDS YP_672056.1 110644326 4188257 complement(4403554..4403754) 1 NC_008253.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4403754 4188257 ECP_4204 Escherichia coli 536 sulfur carrier protein ThiS YP_672056.1 4403554 R 362663 CDS YP_672057.1 110644327 4188258 complement(4403738..4404493) 1 NC_008253.1 adenylyltransferase 4404493 4188258 ECP_4205 Escherichia coli 536 adenylyltransferase YP_672057.1 4403738 R 362663 CDS YP_672058.1 110644328 4188259 complement(4404486..4405121) 1 NC_008253.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4405121 4188259 ECP_4206 Escherichia coli 536 thiamine-phosphate pyrophosphorylase YP_672058.1 4404486 R 362663 CDS YP_672059.1 110644329 4188679 complement(4405121..4407016) 1 NC_008253.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4407016 4188679 ECP_4207 Escherichia coli 536 thiamine biosynthesis protein ThiC YP_672059.1 4405121 R 362663 CDS YP_672060.1 110644330 4188680 complement(4407249..4407725) 1 NC_008253.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4407725 4188680 ECP_4208 Escherichia coli 536 anti-RNA polymerase sigma 70 factor YP_672060.1 4407249 R 362663 CDS YP_672061.1 110644331 4188681 4407820..4408593 1 NC_008253.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4408593 nudC 4188681 nudC Escherichia coli 536 NADH pyrophosphatase YP_672061.1 4407820 D 362663 CDS YP_672062.1 110644332 4188682 4408633..4409697 1 NC_008253.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4409697 hemE 4188682 hemE Escherichia coli 536 uroporphyrinogen decarboxylase YP_672062.1 4408633 D 362663 CDS YP_672063.1 110644333 4188683 4409707..4410378 1 NC_008253.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4410378 4188683 ECP_4211 Escherichia coli 536 endonuclease V YP_672063.1 4409707 D 362663 CDS YP_672064.1 110644334 4188684 4410421..4411011 1 NC_008253.1 hypothetical protein 4411011 4188684 ECP_4212 Escherichia coli 536 hypothetical protein YP_672064.1 4410421 D 362663 CDS YP_672065.1 110644335 4188685 4411198..4411470 1 NC_008253.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4411470 4188685 ECP_4213 Escherichia coli 536 transcriptional regulator HU subunit alpha YP_672065.1 4411198 D 362663 CDS YP_672066.1 110644336 4188686 4411543..4412178 1 NC_008253.1 hypothetical protein 4412178 4188686 ECP_4214 Escherichia coli 536 hypothetical protein YP_672066.1 4411543 D 362663 CDS YP_672067.1 110644337 4188687 complement(4412180..4412599) 1 NC_008253.1 zinc resistance protein 4412599 zraP 4188687 zraP Escherichia coli 536 zinc resistance protein YP_672067.1 4412180 R 362663 CDS YP_672068.1 110644338 4188688 4412837..4414213 1 NC_008253.1 sensor protein ZraS 4414213 4188688 ECP_4216 Escherichia coli 536 sensor protein ZraS YP_672068.1 4412837 D 362663 CDS YP_672069.1 110644339 4188689 4414210..4415535 1 NC_008253.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4415535 4188689 ECP_4217 Escherichia coli 536 transcriptional regulatory protein ZraR YP_672069.1 4414210 D 362663 CDS YP_672070.1 110644340 4188690 complement(4415532..4416821) 1 NC_008253.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4416821 4188690 ECP_4218 Escherichia coli 536 phosphoribosylamine--glycine ligase YP_672070.1 4415532 R 362663 CDS YP_672071.1 110644341 4188691 complement(4416833..4418422) 1 NC_008253.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4418422 purH 4188691 purH Escherichia coli 536 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_672071.1 4416833 R 362663 CDS YP_672072.1 110644342 4188693 4424126..4424509 1 NC_008253.1 hypothetical protein 4424509 4188693 ECP_4221 Escherichia coli 536 hypothetical protein YP_672072.1 4424126 D 362663 CDS YP_672073.1 110644343 4188694 complement(4424573..4425016) 1 NC_008253.1 hypothetical protein 4425016 4188694 ECP_4222 Escherichia coli 536 hypothetical protein YP_672073.1 4424573 R 362663 CDS YP_672074.1 110644344 4188695 4425173..4426102 1 NC_008253.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4426102 4188695 ECP_4223 Escherichia coli 536 homoserine O-succinyltransferase YP_672074.1 4425173 D 362663 CDS YP_672075.1 110644345 4188696 4426371..4427972 1 NC_008253.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4427972 4188696 ECP_4224 Escherichia coli 536 malate synthase YP_672075.1 4426371 D 362663 CDS YP_672076.1 110644346 4188923 4428002..4429306 1 NC_008253.1 isocitrate lyase 4429306 4188923 ECP_4225 Escherichia coli 536 isocitrate lyase YP_672076.1 4428002 D 362663 CDS YP_672077.1 110644347 4188924 4429522..4431246 1 NC_008253.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4431246 aceK 4188924 aceK Escherichia coli 536 bifunctional isocitrate dehydrogenase kinase/phosphatase YP_672077.1 4429522 D 362663 CDS YP_672078.1 110644348 4188925 complement(4431263..4432087) 1 NC_008253.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4432087 4188925 ECP_4227 Escherichia coli 536 IclR family transcriptional regulator YP_672078.1 4431263 R 362663 CDS YP_672079.1 110644349 4188926 4432272..4435970 1 NC_008253.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4435970 metH 4188926 metH Escherichia coli 536 B12-dependent methionine synthase YP_672079.1 4432272 D 362663 CDS YP_672080.1 110644350 4188927 4436030..4436350 1 NC_008253.1 hypothetical protein 4436350 4188927 ECP_4229 Escherichia coli 536 hypothetical protein YP_672080.1 4436030 D 362663 CDS YP_672081.1 110644351 4188928 4436393..4436842 1 NC_008253.1 hypothetical protein 4436842 4188928 ECP_4230 Escherichia coli 536 hypothetical protein YP_672081.1 4436393 D 362663 CDS YP_672082.1 110644352 4188929 4437013..4438644 1 NC_008253.1 hypothetical protein 4438644 4188929 ECP_4231 Escherichia coli 536 hypothetical protein YP_672082.1 4437013 D 362663 CDS YP_672083.1 110644353 4188930 complement(4438734..4439423) 1 NC_008253.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4439423 4188930 ECP_4232 Escherichia coli 536 peptidase E YP_672083.1 4438734 R 362663 CDS YP_672084.1 110644354 4188931 complement(4439805..4441034) 1 NC_008253.1 L-sorbose 1-phosphate reductase 4441034 4188931 ECP_4233 Escherichia coli 536 L-sorbose 1-phosphate reductase YP_672084.1 4439805 R 362663 CDS YP_672085.1 110644355 4188932 complement(4441086..4441910) 1 NC_008253.1 PTS system, sorbose-specific IID component 4441910 4188932 ECP_4234 Escherichia coli 536 PTS system, sorbose-specific IID component YP_672085.1 4441086 R 362663 CDS YP_672086.1 110644356 4188933 complement(4441921..4442718) 1 NC_008253.1 PTS system sorbose-specific transporter subunit IIC 4442718 4188933 ECP_4235 Escherichia coli 536 PTS system sorbose-specific transporter subunit IIC YP_672086.1 4441921 R 362663 CDS YP_672087.1 110644357 4188934 complement(4442784..4443278) 1 NC_008253.1 PTS system, sorbose-specific IIB component 4443278 4188934 ECP_4236 Escherichia coli 536 PTS system, sorbose-specific IIB component YP_672087.1 4442784 R 362663 CDS YP_672088.1 110644358 4188935 complement(4443278..4443685) 1 NC_008253.1 PTS system, sorbose-specific IIA component 4443685 4188935 ECP_4237 Escherichia coli 536 PTS system, sorbose-specific IIA component YP_672088.1 4443278 R 362663 CDS YP_672089.1 110644359 4188936 complement(4443695..4444501) 1 NC_008253.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4444501 4188936 ECP_4238 Escherichia coli 536 sorbitol-6-phosphate 2-dehydrogenase YP_672089.1 4443695 R 362663 CDS YP_672090.1 110644360 4188937 complement(4444571..4445518) 1 NC_008253.1 transcriptional regulator of sorbose uptake and utilization genes 4445518 4188937 ECP_4239 Escherichia coli 536 transcriptional regulator of sorbose uptake and utilization genes YP_672090.1 4444571 R 362663 CDS YP_672091.1 110644361 4188938 4445866..4446738 1 NC_008253.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4446738 4188938 ECP_4240 Escherichia coli 536 23S rRNA pseudouridine synthase F YP_672091.1 4445866 D 362663 CDS YP_672092.1 110644362 4188939 complement(4446739..4447011) 1 NC_008253.1 hypothetical protein 4447011 4188939 ECP_4241 Escherichia coli 536 hypothetical protein YP_672092.1 4446739 R 362663 CDS YP_672093.1 110644363 4188940 complement(4447264..4448613) 1 NC_008253.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 4448613 4188940 ECP_4242 Escherichia coli 536 aspartate kinase YP_672093.1 4447264 R 362663 CDS YP_672094.1 110644364 4188941 4449138..4450787 1 NC_008253.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4450787 pgi 4188941 pgi Escherichia coli 536 glucose-6-phosphate isomerase YP_672094.1 4449138 D 362663 CDS YP_672095.1 110644365 4188942 4451286..4451528 1 NC_008253.1 hypothetical protein 4451528 4188942 ECP_4244 Escherichia coli 536 hypothetical protein YP_672095.1 4451286 D 362663 CDS YP_672096.1 110644366 4187946 4451715..4452353 1 NC_008253.1 lipoprotein YjbF 4452353 4187946 ECP_4245 Escherichia coli 536 lipoprotein YjbF YP_672096.1 4451715 D 362663 CDS YP_672097.1 110644367 4187947 4452350..4453087 1 NC_008253.1 hypothetical protein 4453087 4187947 ECP_4246 Escherichia coli 536 hypothetical protein YP_672097.1 4452350 D 362663 CDS YP_672098.1 110644368 4187948 4453087..4455183 1 NC_008253.1 lipoprotein YjbH 4455183 4187948 ECP_4247 Escherichia coli 536 lipoprotein YjbH YP_672098.1 4453087 D 362663 CDS YP_672099.1 110644369 4187949 4455568..4455726 1 NC_008253.1 hypothetical protein 4455726 4187949 ECP_4248 Escherichia coli 536 hypothetical protein YP_672099.1 4455568 D 362663 CDS YP_672100.1 110644370 4187950 4455723..4456133 1 NC_008253.1 phosphate-starvation-inducible protein PsiE 4456133 4187950 ECP_4249 Escherichia coli 536 phosphate-starvation-inducible protein PsiE YP_672100.1 4455723 D 362663 CDS YP_672101.1 110644371 4187951 complement(4456227..4457117) 1 NC_008253.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4457117 malG 4187951 malG Escherichia coli 536 maltose transporter permease YP_672101.1 4456227 R 362663 CDS YP_672102.1 110644372 4187952 complement(4457132..4458676) 1 NC_008253.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4458676 malF 4187952 malF Escherichia coli 536 maltose transporter membrane protein YP_672102.1 4457132 R 362663 CDS YP_672103.1 110644373 4187953 complement(4458830..4460020) 1 NC_008253.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4460020 malE 4187953 malE Escherichia coli 536 maltose ABC transporter periplasmic protein YP_672103.1 4458830 R 362663 CDS YP_672104.1 110644374 4187954 4460385..4461500 1 NC_008253.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4461500 4187954 ECP_4253 Escherichia coli 536 maltose/maltodextrin transporter ATP-binding protein YP_672104.1 4460385 D 362663 CDS YP_672105.1 110644375 4187955 4461572..4462912 1 NC_008253.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4462912 lamB 4187955 lamB Escherichia coli 536 maltoporin YP_672105.1 4461572 D 362663 CDS YP_672106.1 110644376 4187956 4463235..4464155 1 NC_008253.1 maltose regulon periplasmic protein 4464155 4187956 ECP_4255 Escherichia coli 536 maltose regulon periplasmic protein YP_672106.1 4463235 D 362663 CDS YP_672107.1 110644377 4187957 4464334..4464831 1 NC_008253.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4464831 ubiC 4187957 ubiC Escherichia coli 536 chorismate pyruvate lyase YP_672107.1 4464334 D 362663 CDS YP_672108.1 110644378 4187958 4464844..4465716 1 NC_008253.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4465716 ubiA 4187958 ubiA Escherichia coli 536 4-hydroxybenzoate octaprenyltransferase YP_672108.1 4464844 D 362663 CDS YP_672109.1 110644379 4187961 4468464..4468832 1 NC_008253.1 diacylglycerol kinase 4468832 4187961 ECP_4260 Escherichia coli 536 diacylglycerol kinase YP_672109.1 4468464 D 362663 CDS YP_672110.1 110644380 4187962 4468942..4469550 1 NC_008253.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4469550 4187962 ECP_4261 Escherichia coli 536 LexA repressor YP_672110.1 4468942 D 362663 CDS YP_672111.1 110644381 4189333 4469569..4470948 1 NC_008253.1 DNA-damage-inducible SOS response protein 4470948 4189333 ECP_4262 Escherichia coli 536 DNA-damage-inducible SOS response protein YP_672111.1 4469569 D 362663 CDS YP_672112.1 110644382 4189334 4471064..4471273 1 NC_008253.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4471273 4189334 ECP_4263 Escherichia coli 536 stress-response protein YP_672112.1 4471064 D 362663 CDS YP_672113.1 110644383 4189335 complement(4471315..4471908) 1 NC_008253.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4471908 4189335 ECP_4264 Escherichia coli 536 zinc uptake transcriptional repressor YP_672113.1 4471315 R 362663 CDS YP_672114.1 110644384 4189336 4471986..4472981 1 NC_008253.1 tRNA-dihydrouridine synthase A 4472981 4189336 ECP_4265 Escherichia coli 536 tRNA-dihydrouridine synthase A YP_672114.1 4471986 D 362663 CDS YP_672115.1 110644385 4189337 4472938..4473357 1 NC_008253.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4473357 pspG 4189337 pspG Escherichia coli 536 phage shock protein G YP_672115.1 4472938 D 362663 CDS YP_672116.1 110644386 4189338 complement(4473522..4474505) 1 NC_008253.1 quinone oxidoreductase 4474505 4189338 ECP_4267 Escherichia coli 536 quinone oxidoreductase YP_672116.1 4473522 R 362663 CDS YP_672117.1 110644387 4189339 4474588..4476003 1 NC_008253.1 unwinds double stranded DNA; replicative DNA helicase 4476003 4189339 ECP_4268 Escherichia coli 536 replicative DNA helicase YP_672117.1 4474588 D 362663 CDS YP_672118.1 110644388 4189340 complement(4476038..4476658) 1 NC_008253.1 hypothetical protein 4476658 4189340 ECP_4269 Escherichia coli 536 hypothetical protein YP_672118.1 4476038 R 362663 CDS YP_672119.1 110644389 4189341 4476725..4477804 1 NC_008253.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4477804 alr 4189341 alr Escherichia coli 536 alanine racemase YP_672119.1 4476725 D 362663 CDS YP_672120.1 110644390 4189342 4477827..4478384 1 NC_008253.1 hypothetical protein 4478384 4189342 ECP_4271 Escherichia coli 536 hypothetical protein YP_672120.1 4477827 D 362663 CDS YP_672121.1 110644391 4189343 4478381..4479385 1 NC_008253.1 hypothetical protein 4479385 4189343 ECP_4272 Escherichia coli 536 hypothetical protein YP_672121.1 4478381 D 362663 CDS YP_672122.1 110644392 4189344 4479467..4480660 1 NC_008253.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4480660 4189344 ECP_4273 Escherichia coli 536 aromatic amino acid aminotransferase YP_672122.1 4479467 D 362663 CDS YP_672123.1 110644393 4189345 4480842..4483586 1 NC_008253.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4483586 sucA 4189345 sucA Escherichia coli 536 2-oxoglutarate dehydrogenase E1 YP_672123.1 4480842 D 362663 CDS YP_672124.1 110644394 4189346 4483619..4484773 1 NC_008253.1 component of 2-oxoglutarate dehydrogenase complex; dihydrolipoamide succinyltransferase 4484773 4189346 ECP_4275 Escherichia coli 536 dihydrolipoamide succinyltransferase YP_672124.1 4483619 D 362663 CDS YP_672125.1 110644395 4189347 4484785..4486203 1 NC_008253.1 pyridine nucleotide-disulfide oxidoreductase 4486203 4189347 ECP_4276 Escherichia coli 536 pyridine nucleotide-disulfide oxidoreductase YP_672125.1 4484785 D 362663 CDS YP_672126.1 110644396 4189348 4486225..4487394 1 NC_008253.1 succinyl-CoA synthetase beta chain 4487394 4189348 ECP_4277 Escherichia coli 536 succinyl-CoA synthetase beta chain YP_672126.1 4486225 D 362663 CDS YP_672127.1 110644397 4189349 4487407..4488279 1 NC_008253.1 succinyl-CoA synthetase subunit alpha 4488279 4189349 ECP_4278 Escherichia coli 536 succinyl-CoA synthetase subunit alpha YP_672127.1 4487407 D 362663 CDS YP_672128.1 110644398 4189350 4488491..4489990 1 NC_008253.1 sodium:sulfate symporter transmembrane protein 4489990 4189350 ECP_4279 Escherichia coli 536 sodium:sulfate symporter transmembrane protein YP_672128.1 4488491 D 362663 CDS YP_672129.1 110644399 4189351 4490002..4491075 1 NC_008253.1 malate/L-lactate dehydrogenase YbiC 4491075 4189351 ECP_4280 Escherichia coli 536 malate/L-lactate dehydrogenase YbiC YP_672129.1 4490002 D 362663 CDS YP_672130.1 110644400 4187831 complement(4491064..4492422) 1 NC_008253.1 two component response regulator 4492422 4187831 ECP_4281 Escherichia coli 536 two component response regulator YP_672130.1 4491064 R 362663 CDS YP_672131.1 110644401 4187832 complement(4492415..4494235) 1 NC_008253.1 transport sensor protein 4494235 4187832 ECP_4282 Escherichia coli 536 transport sensor protein YP_672131.1 4492415 R 362663 CDS YP_672132.1 110644402 4187833 4494512..4495225 1 NC_008253.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4495225 aphA 4187833 aphA Escherichia coli 536 acid phosphatase/phosphotransferase YP_672132.1 4494512 D 362663 CDS YP_672133.1 110644403 4187834 4495336..4495752 1 NC_008253.1 hypothetical protein 4495752 4187834 ECP_4284 Escherichia coli 536 hypothetical protein YP_672133.1 4495336 D 362663 CDS YP_672134.1 110644404 4187835 4495756..4496112 1 NC_008253.1 hypothetical protein 4496112 4187835 ECP_4285 Escherichia coli 536 hypothetical protein YP_672134.1 4495756 D 362663 CDS YP_672135.1 110644405 4187836 complement(4496147..4498969) 1 NC_008253.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4498969 uvrA 4187836 uvrA Escherichia coli 536 excinuclease ABC subunit A YP_672135.1 4496147 R 362663 CDS YP_672136.1 110644406 4187837 4499224..4499760 1 NC_008253.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4499760 4187837 ECP_4287 Escherichia coli 536 single-stranded DNA-binding protein YP_672136.1 4499224 D 362663 CDS YP_672137.1 110644407 4187838 complement(4499859..4500140) 1 NC_008253.1 hypothetical protein 4500140 4187838 ECP_4288 Escherichia coli 536 hypothetical protein YP_672137.1 4499859 R 362663 CDS YP_672138.1 110644408 4187839 4500569..4502155 1 NC_008253.1 hypothetical protein 4502155 4187839 ECP_4289 Escherichia coli 536 hypothetical protein YP_672138.1 4500569 D 362663 CDS YP_672139.1 110644409 4187840 complement(4502158..4502481) 1 NC_008253.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4502481 4187840 ECP_4290 Escherichia coli 536 DNA-binding transcriptional regulator SoxS YP_672139.1 4502158 R 362663 CDS YP_672140.1 110644410 4187841 4502567..4503031 1 NC_008253.1 redox-sensitive transcriptional activator SoxR 4503031 4187841 ECP_4291 Escherichia coli 536 redox-sensitive transcriptional activator SoxR YP_672140.1 4502567 D 362663 CDS YP_672141.1 110644411 4187842 complement(4503322..4503537) 1 NC_008253.1 hypothetical protein 4503537 4187842 ECP_4292 Escherichia coli 536 hypothetical protein YP_672141.1 4503322 R 362663 CDS YP_672142.1 110644412 4187843 4503578..4504927 1 NC_008253.1 xanthine/uracil permeases family protein YjcD 4504927 4187843 ECP_4293 Escherichia coli 536 xanthine/uracil permeases family protein YjcD YP_672142.1 4503578 D 362663 CDS YP_672143.1 110644413 4187844 4505078..4506727 1 NC_008253.1 sodium/hydrogen exchanger family protein YjcE 4506727 4187844 ECP_4294 Escherichia coli 536 sodium/hydrogen exchanger family protein YjcE YP_672143.1 4505078 D 362663 CDS YP_672144.1 110644414 4187845 complement(4506763..4507095) 1 NC_008253.1 hypothetical protein 4507095 4187845 ECP_4295 Escherichia coli 536 hypothetical protein YP_672144.1 4506763 R 362663 CDS YP_672145.1 110644415 4187846 complement(4507166..4507558) 1 NC_008253.1 hypothetical protein 4507558 4187846 ECP_4296 Escherichia coli 536 hypothetical protein YP_672145.1 4507166 R 362663 CDS YP_672146.1 110644416 4187847 4507662..4508072 1 NC_008253.1 murein hydrolase exporter 4508072 4187847 ECP_4297 Escherichia coli 536 murein hydrolase exporter YP_672146.1 4507662 D 362663 CDS YP_672147.1 110644417 4187848 4508065..4508754 1 NC_008253.1 LrgB family murein hydrolase regulator 4508754 4187848 ECP_4298 Escherichia coli 536 LrgB family murein hydrolase regulator YP_672147.1 4508065 D 362663 CDS YP_672148.1 110644418 4187849 complement(4508793..4510442) 1 NC_008253.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4510442 actP 4187849 actP Escherichia coli 536 acetate permease YP_672148.1 4508793 R 362663 CDS YP_672149.1 110644419 4187850 complement(4510439..4510753) 1 NC_008253.1 hypothetical protein 4510753 4187850 ECP_4300 Escherichia coli 536 hypothetical protein YP_672149.1 4510439 R 362663 CDS YP_672150.1 110644420 4187304 complement(4511056..4513014) 1 NC_008253.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4513014 4187304 ECP_4301 Escherichia coli 536 acetyl-CoA synthetase YP_672150.1 4511056 R 362663 CDS YP_672151.1 110644421 4187305 4513288..4513485 1 NC_008253.1 hypothetical protein 4513485 4187305 ECP_4302 Escherichia coli 536 hypothetical protein YP_672151.1 4513288 D 362663 CDS YP_672152.1 110644422 4187306 4513406..4514842 1 NC_008253.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4514842 nrfA 4187306 nrfA Escherichia coli 536 cytochrome c552 YP_672152.1 4513406 D 362663 CDS YP_672153.1 110644423 4187307 4514887..4515453 1 NC_008253.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4515453 4187307 ECP_4304 Escherichia coli 536 cytochrome c nitrite reductase pentaheme subunit YP_672153.1 4514887 D 362663 CDS YP_672154.1 110644424 4187308 4515450..4516121 1 NC_008253.1 NrfC protein 4516121 4187308 ECP_4305 Escherichia coli 536 NrfC protein YP_672154.1 4515450 D 362663 CDS YP_672155.1 110644425 4187309 4516118..4517074 1 NC_008253.1 NrfD protein 4517074 4187309 ECP_4306 Escherichia coli 536 NrfD protein YP_672155.1 4516118 D 362663 CDS YP_672156.1 110644426 4187310 4517154..4518812 1 NC_008253.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4518812 4187310 ECP_4307 Escherichia coli 536 heme lyase subunit NrfE YP_672156.1 4517154 D 362663 CDS YP_672157.1 110644427 4187311 4518805..4519188 1 NC_008253.1 formate-dependent nitrite reductase complex subunit NrfF 4519188 4187311 ECP_4308 Escherichia coli 536 formate-dependent nitrite reductase complex subunit NrfF YP_672157.1 4518805 D 362663 CDS YP_672158.1 110644428 4187312 4519185..4519781 1 NC_008253.1 formate-dependent nitrite reductase complex subunit NrfG 4519781 4187312 ECP_4309 Escherichia coli 536 formate-dependent nitrite reductase complex subunit NrfG YP_672158.1 4519185 D 362663 CDS YP_672159.1 110644429 4187313 4520124..4521437 1 NC_008253.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4521437 gltP 4187313 gltP Escherichia coli 536 glutamate/aspartate:proton symporter YP_672159.1 4520124 D 362663 CDS YP_672160.1 110644430 4187314 4522153..4522674 1 NC_008253.1 IS transposase 4522674 4187314 ECP_4311 Escherichia coli 536 IS transposase YP_672160.1 4522153 D 362663 CDS YP_672161.1 110644431 4187315 4522779..4523501 1 NC_008253.1 transposase 4523501 4187315 ECP_4312 Escherichia coli 536 transposase YP_672161.1 4522779 D 362663 CDS YP_672162.1 110644432 4187316 complement(4523699..4524388) 1 NC_008253.1 hypothetical protein 4524388 4187316 ECP_4313 Escherichia coli 536 hypothetical protein YP_672162.1 4523699 R 362663 CDS YP_672163.1 110644433 4187317 complement(4524499..4525203) 1 NC_008253.1 ABC transporter ATP-binding protein 4525203 4187317 ECP_4314 Escherichia coli 536 ABC transporter ATP-binding protein YP_672163.1 4524499 R 362663 CDS YP_672164.1 110644434 4187318 complement(4525190..4526044) 1 NC_008253.1 ABC transporter transporter ATP-binding protein 4526044 4187318 ECP_4315 Escherichia coli 536 ABC transporter transporter ATP-binding protein YP_672164.1 4525190 R 362663 CDS YP_672165.1 110644435 4187319 complement(4526019..4526852) 1 NC_008253.1 transporter permease 4526852 4187319 ECP_4316 Escherichia coli 536 transporter permease YP_672165.1 4526019 R 362663 CDS YP_672166.1 110644436 4187320 complement(4526852..4527994) 1 NC_008253.1 transporter permease 4527994 4187320 ECP_4317 Escherichia coli 536 transporter permease YP_672166.1 4526852 R 362663 CDS YP_672167.1 110644437 4187321 complement(4528001..4529569) 1 NC_008253.1 dipeptide binding periplasmic protein 4529569 4187321 ECP_4318 Escherichia coli 536 dipeptide binding periplasmic protein YP_672167.1 4528001 R 362663 CDS YP_672168.1 110644438 4190354 complement(4532289..4533755) 1 NC_008253.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4533755 4190354 ECP_4321 Escherichia coli 536 outer membrane efflux protein MdtP YP_672168.1 4532289 R 362663 CDS YP_672169.1 110644439 4190355 complement(4533752..4535803) 1 NC_008253.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4535803 4190355 ECP_4322 Escherichia coli 536 multidrug efflux system protein MdtO YP_672169.1 4533752 R 362663 CDS YP_672170.1 110644440 4190356 complement(4535803..4536834) 1 NC_008253.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4536834 4190356 ECP_4323 Escherichia coli 536 multidrug resistance protein MdtN YP_672170.1 4535803 R 362663 CDS YP_672171.1 110644441 4190357 complement(4536853..4537128) 1 NC_008253.1 hypothetical protein 4537128 4190357 ECP_4324 Escherichia coli 536 hypothetical protein YP_672171.1 4536853 R 362663 CDS YP_672172.1 110644442 4190358 complement(4537337..4539322) 1 NC_008253.1 hypothetical protein 4539322 4190358 ECP_4325 Escherichia coli 536 hypothetical protein YP_672172.1 4537337 R 362663 CDS YP_672173.1 110644443 4190359 complement(4539595..4540524) 1 NC_008253.1 D-allose kinase 4540524 4190359 ECP_4326 Escherichia coli 536 D-allose kinase YP_672173.1 4539595 R 362663 CDS YP_672174.1 110644444 4190360 complement(4540508..4541203) 1 NC_008253.1 allulose-6-phosphate 3-epimerase 4541203 4190360 ECP_4327 Escherichia coli 536 allulose-6-phosphate 3-epimerase YP_672174.1 4540508 R 362663 CDS YP_672175.1 110644445 4190363 complement(4542172..4543704) 1 NC_008253.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4543704 4190363 ECP_4330 Escherichia coli 536 D-allose transporter ATP-binding protein YP_672175.1 4542172 R 362663 CDS YP_672176.1 110644446 4190364 complement(4543832..4544773) 1 NC_008253.1 D-allose transporter subunit 4544773 4190364 ECP_4331 Escherichia coli 536 D-allose transporter subunit YP_672176.1 4543832 R 362663 CDS YP_672177.1 110644447 4190365 complement(4544826..4545716) 1 NC_008253.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4545716 4190365 ECP_4332 Escherichia coli 536 DNA-binding transcriptional repressor RpiR YP_672177.1 4544826 R 362663 CDS YP_672178.1 110644448 4190366 4546075..4546524 1 NC_008253.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4546524 4190366 ECP_4333 Escherichia coli 536 ribose-5-phosphate isomerase B YP_672178.1 4546075 D 362663 CDS YP_672179.1 110644449 4190367 4546593..4546922 1 NC_008253.1 hypothetical protein 4546922 4190367 ECP_4334 Escherichia coli 536 hypothetical protein YP_672179.1 4546593 D 362663 CDS YP_672180.1 110644450 4187226 complement(4546950..4547708) 1 NC_008253.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4547708 phnP 4187226 phnP Escherichia coli 536 carbon-phosphorus lyase complex accessory protein YP_672180.1 4546950 R 362663 CDS YP_672181.1 110644451 4187227 complement(4547710..4548144) 1 NC_008253.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4548144 4187227 ECP_4336 Escherichia coli 536 aminoalkylphosphonic acid N-acetyltransferase YP_672181.1 4547710 R 362663 CDS YP_672182.1 110644452 4187228 complement(4548131..4548688) 1 NC_008253.1 ribose 1,5-bisphosphokinase 4548688 4187228 ECP_4337 Escherichia coli 536 ribose 1,5-bisphosphokinase YP_672182.1 4548131 R 362663 CDS YP_672183.1 110644453 4187229 complement(4548688..4549824) 1 NC_008253.1 HisM-like integral membrane protein PhnM 4549824 4187229 ECP_4338 Escherichia coli 536 HisM-like integral membrane protein PhnM YP_672183.1 4548688 R 362663 CDS YP_672184.1 110644454 4187230 complement(4549821..4550501) 1 NC_008253.1 phosphonates transport ATP-binding protein PhnL 4550501 4187230 ECP_4339 Escherichia coli 536 phosphonates transport ATP-binding protein PhnL YP_672184.1 4549821 R 362663 CDS YP_672185.1 110644455 4187231 complement(4550612..4551370) 1 NC_008253.1 phosphonate C-P lyase system protein PhnK 4551370 phnK 4187231 phnK Escherichia coli 536 phosphonate C-P lyase system protein PhnK YP_672185.1 4550612 R 362663 CDS YP_672186.1 110644456 4187232 complement(4551367..4552212) 1 NC_008253.1 PhnJ protein 4552212 4187232 ECP_4341 Escherichia coli 536 PhnJ protein YP_672186.1 4551367 R 362663 CDS YP_672187.1 110644457 4187233 complement(4552205..4553269) 1 NC_008253.1 PhnI protein 4553269 4187233 ECP_4342 Escherichia coli 536 PhnI protein YP_672187.1 4552205 R 362663 CDS YP_672188.1 110644458 4187234 complement(4553269..4553853) 1 NC_008253.1 carbon-phosphorus lyase complex subunit 4553853 phnH 4187234 phnH Escherichia coli 536 carbon-phosphorus lyase complex subunit YP_672188.1 4553269 R 362663 CDS YP_672189.1 110644459 4187235 complement(4553850..4554302) 1 NC_008253.1 PhnG protein 4554302 4187235 ECP_4344 Escherichia coli 536 PhnG protein YP_672189.1 4553850 R 362663 CDS YP_672190.1 110644460 4187236 complement(4554303..4555028) 1 NC_008253.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4555028 4187236 ECP_4345 Escherichia coli 536 phosphonate metabolism transcriptional regulator PhnF YP_672190.1 4554303 R 362663 CDS YP_672191.1 110644461 4187237 complement(4555049..4555828) 1 NC_008253.1 phosphonates transport system permease PhnE 4555828 4187237 ECP_4346 Escherichia coli 536 phosphonates transport system permease PhnE YP_672191.1 4555049 R 362663 CDS YP_672192.1 110644462 4187238 complement(4555934..4556950) 1 NC_008253.1 PhnD protein 4556950 4187238 ECP_4347 Escherichia coli 536 PhnD protein YP_672192.1 4555934 R 362663 CDS YP_672193.1 110644463 4187239 complement(4556975..4557763) 1 NC_008253.1 phosphonate/organophosphate ester transporter subunit 4557763 4187239 ECP_4348 Escherichia coli 536 phosphonate/organophosphate ester transporter subunit YP_672193.1 4556975 R 362663 CDS YP_672194.1 110644464 4187240 complement(4557896..4558339) 1 NC_008253.1 hypothetical protein 4558339 4187240 ECP_4349 Escherichia coli 536 hypothetical protein YP_672194.1 4557896 R 362663 CDS YP_672195.1 110644465 4187241 complement(4558499..4558834) 1 NC_008253.1 hypothetical protein 4558834 4187241 ECP_4350 Escherichia coli 536 hypothetical protein YP_672195.1 4558499 R 362663 CDS YP_672196.1 110644466 4187242 4558806..4559018 1 NC_008253.1 hypothetical protein 4559018 4187242 ECP_4351 Escherichia coli 536 hypothetical protein YP_672196.1 4558806 D 362663 CDS YP_672197.1 110644467 4187243 4559237..4561465 1 NC_008253.1 hypothetical protein 4561465 4187243 ECP_4352 Escherichia coli 536 hypothetical protein YP_672197.1 4559237 D 362663 CDS YP_672198.1 110644468 4187244 4561462..4562340 1 NC_008253.1 hypothetical protein 4562340 4187244 ECP_4353 Escherichia coli 536 hypothetical protein YP_672198.1 4561462 D 362663 CDS YP_672199.1 110644469 4191628 4562604..4564106 1 NC_008253.1 proline/glycine betaine transporter 4564106 4191628 ECP_4354 Escherichia coli 536 proline/glycine betaine transporter YP_672199.1 4562604 D 362663 CDS YP_672200.1 110644470 4191629 complement(4564283..4565374) 1 NC_008253.1 sensor protein BasS/PmrB 4565374 4191629 ECP_4355 Escherichia coli 536 sensor protein BasS/PmrB YP_672200.1 4564283 R 362663 CDS YP_672201.1 110644471 4191630 complement(4565384..4566052) 1 NC_008253.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4566052 4191630 ECP_4356 Escherichia coli 536 DNA-binding transcriptional regulator BasR YP_672201.1 4565384 R 362663 CDS YP_672202.1 110644472 4191631 complement(4566049..4567722) 1 NC_008253.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4567722 4191631 ECP_4357 Escherichia coli 536 cell division protein YP_672202.1 4566049 R 362663 CDS YP_672203.1 110644473 4191632 complement(4567796..4569133) 1 NC_008253.1 arginine:agmatin antiporter 4569133 4191632 ECP_4358 Escherichia coli 536 arginine:agmatin antiporter YP_672203.1 4567796 R 362663 CDS YP_672204.1 110644474 4191633 complement(4569270..4570031) 1 NC_008253.1 regulatory protein AdiY 4570031 4191633 ECP_4359 Escherichia coli 536 regulatory protein AdiY YP_672204.1 4569270 R 362663 CDS YP_672205.1 110644475 4191634 complement(4570367..4572637) 1 NC_008253.1 biodegradative arginine decarboxylase 4572637 4191634 ECP_4360 Escherichia coli 536 biodegradative arginine decarboxylase YP_672205.1 4570367 R 362663 CDS YP_672206.1 110644476 4191635 complement(4572833..4573741) 1 NC_008253.1 DNA-binding transcriptional regulator MelR 4573741 4191635 ECP_4361 Escherichia coli 536 DNA-binding transcriptional regulator MelR YP_672206.1 4572833 R 362663 CDS YP_672207.1 110644477 4191636 4574024..4575379 1 NC_008253.1 alpha-galactosidase 4575379 4191636 ECP_4362 Escherichia coli 536 alpha-galactosidase YP_672207.1 4574024 D 362663 CDS YP_672208.1 110644478 4191637 complement(4575376..4576026) 1 NC_008253.1 hypothetical protein 4576026 4191637 ECP_4363 Escherichia coli 536 hypothetical protein YP_672208.1 4575376 R 362663 CDS YP_672209.1 110644479 4191638 complement(4576149..4577795) 1 NC_008253.1 fumarate hydratase class I, anaerobic 4577795 4191638 ECP_4364 Escherichia coli 536 fumarate hydratase class I, anaerobic YP_672209.1 4576149 R 362663 CDS YP_672210.1 110644480 4191639 complement(4577873..4579213) 1 NC_008253.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4579213 4191639 ECP_4365 Escherichia coli 536 anaerobic C4-dicarboxylate transporter YP_672210.1 4577873 R 362663 CDS YP_672211.1 110644481 4191640 4579281..4579439 1 NC_008253.1 hypothetical protein 4579439 4191640 ECP_4366 Escherichia coli 536 hypothetical protein YP_672211.1 4579281 D 362663 CDS YP_672212.1 110644482 4191641 complement(4579784..4580503) 1 NC_008253.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4580503 4191641 ECP_4367 Escherichia coli 536 DNA-binding transcriptional activator DcuR YP_672212.1 4579784 R 362663 CDS YP_672213.1 110644483 4191642 complement(4580500..4582131) 1 NC_008253.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4582131 4191642 ECP_4368 Escherichia coli 536 sensory histidine kinase DcuS YP_672213.1 4580500 R 362663 CDS YP_672214.1 110644484 4191643 4582312..4582542 1 NC_008253.1 hypothetical protein 4582542 4191643 ECP_4369 Escherichia coli 536 hypothetical protein YP_672214.1 4582312 D 362663 CDS YP_672215.1 110644485 4191644 4582554..4582826 1 NC_008253.1 hypothetical protein 4582826 4191644 ECP_4370 Escherichia coli 536 hypothetical protein YP_672215.1 4582554 D 362663 CDS YP_672216.1 110644486 4191645 4583055..4583351 1 NC_008253.1 hypothetical protein 4583351 4191645 ECP_4371 Escherichia coli 536 hypothetical protein YP_672216.1 4583055 D 362663 CDS YP_672217.1 110644487 4191646 4583379..4583552 1 NC_008253.1 hypothetical protein 4583552 4191646 ECP_4372 Escherichia coli 536 hypothetical protein YP_672217.1 4583379 D 362663 CDS YP_672218.1 110644488 4191647 complement(4583671..4585188) 1 NC_008253.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4585188 4191647 ECP_4373 Escherichia coli 536 lysyl-tRNA synthetase YP_672218.1 4583671 R 362663 CDS YP_672219.1 110644489 4190443 complement(4585425..4586882) 1 NC_008253.1 POT family di-/tripeptide transport protein 4586882 4190443 ECP_4374 Escherichia coli 536 POT family di-/tripeptide transport protein YP_672219.1 4585425 R 362663 CDS YP_672220.1 110644490 4190444 complement(4586941..4589088) 1 NC_008253.1 lysine decarboxylase, inducible 4589088 4190444 ECP_4375 Escherichia coli 536 lysine decarboxylase, inducible YP_672220.1 4586941 R 362663 CDS YP_672221.1 110644491 4190445 complement(4589168..4590502) 1 NC_008253.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4590502 cadB 4190445 cadB Escherichia coli 536 lysine/cadaverine antiporter YP_672221.1 4589168 R 362663 CDS YP_672222.1 110644492 4190446 complement(4590868..4592406) 1 NC_008253.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4592406 4190446 ECP_4377 Escherichia coli 536 DNA-binding transcriptional activator CadC YP_672222.1 4590868 R 362663 CDS YP_672223.1 110644493 4190447 4592693..4592911 1 NC_008253.1 hypothetical protein 4592911 4190447 ECP_4378 Escherichia coli 536 hypothetical protein YP_672223.1 4592693 D 362663 CDS YP_672224.1 110644494 4190448 complement(4593205..4593780) 1 NC_008253.1 transcriptional regulator 4593780 4190448 ECP_4379 Escherichia coli 536 transcriptional regulator YP_672224.1 4593205 R 362663 CDS YP_672225.1 110644495 4190449 complement(4593817..4595514) 1 NC_008253.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4595514 dipZ 4190449 dipZ Escherichia coli 536 thiol:disulfide interchange protein YP_672225.1 4593817 R 362663 CDS YP_672226.1 110644496 4190450 complement(4595490..4595828) 1 NC_008253.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4595828 4190450 ECP_4381 Escherichia coli 536 divalent-cation tolerance protein CutA YP_672226.1 4595490 R 362663 CDS YP_672227.1 110644497 4190451 complement(4595944..4597245) 1 NC_008253.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4597245 4190451 ECP_4382 Escherichia coli 536 anaerobic C4-dicarboxylate transporter YP_672227.1 4595944 R 362663 CDS YP_672228.1 110644498 4190452 complement(4597363..4598799) 1 NC_008253.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4598799 aspA 4190452 aspA Escherichia coli 536 aspartate ammonia-lyase YP_672228.1 4597363 R 362663 CDS YP_672229.1 110644499 4190453 4599136..4599612 1 NC_008253.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4599612 fxsA 4190453 fxsA Escherichia coli 536 FxsA protein YP_672229.1 4599136 D 362663 CDS YP_672230.1 110644500 4190454 complement(4599628..4600884) 1 NC_008253.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 4600884 4190454 ECP_4385 Escherichia coli 536 hypothetical protein YP_672230.1 4599628 R 362663 CDS YP_672231.1 110644501 4190455 4601160..4601453 1 NC_008253.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4601453 groES 4190455 groES Escherichia coli 536 co-chaperonin GroES YP_672231.1 4601160 D 362663 CDS YP_672232.1 110644502 4190456 4601497..4603143 1 NC_008253.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4603143 groEL 4190456 groEL Escherichia coli 536 molecular chaperone GroEL YP_672232.1 4601497 D 362663 CDS YP_672233.1 110644503 4190457 4603281..4603634 1 NC_008253.1 hypothetical protein 4603634 4190457 ECP_4388 Escherichia coli 536 hypothetical protein YP_672233.1 4603281 D 362663 CDS YP_672234.1 110644504 4190458 complement(4603684..4604553) 1 NC_008253.1 hypothetical protein 4604553 4190458 ECP_4389 Escherichia coli 536 hypothetical protein YP_672234.1 4603684 R 362663 CDS YP_672235.1 110644505 4190459 complement(4604788..4605816) 1 NC_008253.1 hypothetical protein 4605816 4190459 ECP_4390 Escherichia coli 536 hypothetical protein YP_672235.1 4604788 R 362663 CDS YP_672236.1 110644506 4190460 4605858..4606424 1 NC_008253.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4606424 4190460 ECP_4391 Escherichia coli 536 elongation factor P YP_672236.1 4605858 D 362663 CDS YP_672237.1 110644507 4190461 4606476..4606601 1 NC_008253.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4606601 4190461 ECP_4392 Escherichia coli 536 entericidin A YP_672237.1 4606476 D 362663 CDS YP_672238.1 110644508 4190197 4606712..4606858 1 NC_008253.1 entericidin B 4606858 4190197 ECP_4393 Escherichia coli 536 entericidin B YP_672238.1 4606712 D 362663 CDS YP_672239.1 110644509 4190198 4607048..4607365 1 NC_008253.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4607365 4190198 ECP_4394 Escherichia coli 536 quaternary ammonium compound-resistance protein SugE YP_672239.1 4607048 D 362663 CDS YP_672240.1 110644510 4190199 complement(4607362..4607895) 1 NC_008253.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4607895 4190199 ECP_4395 Escherichia coli 536 outer membrane lipoprotein Blc YP_672240.1 4607362 R 362663 CDS YP_672241.1 110644511 4190200 complement(4607984..4609246) 1 NC_008253.1 beta-lactamase 4609246 ampC 4190200 ampC Escherichia coli 536 beta-lactamase YP_672241.1 4607984 R 362663 CDS YP_672242.1 110644512 4190201 complement(4609180..4609539) 1 NC_008253.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4609539 4190201 ECP_4397 Escherichia coli 536 fumarate reductase subunit D YP_672242.1 4609180 R 362663 CDS YP_672243.1 110644513 4190202 complement(4609550..4609945) 1 NC_008253.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4609945 4190202 ECP_4398 Escherichia coli 536 fumarate reductase subunit C YP_672243.1 4609550 R 362663 CDS YP_672244.1 110644514 4190203 complement(4609956..4610690) 1 NC_008253.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4610690 4190203 ECP_4399 Escherichia coli 536 fumarate reductase iron-sulfur subunit YP_672244.1 4609956 R 362663 CDS YP_672245.1 110644515 4190204 complement(4610683..4612491) 1 NC_008253.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4612491 4190204 ECP_4400 Escherichia coli 536 fumarate reductase flavoprotein subunit YP_672245.1 4610683 R 362663 CDS YP_672246.1 110644516 4190205 4612816..4613793 1 NC_008253.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4613793 4190205 ECP_4401 Escherichia coli 536 lysyl-tRNA synthetase YP_672246.1 4612816 D 362663 CDS YP_672247.1 110644517 4190206 4614012..4615514 1 NC_008253.1 transporter YjeM 4615514 4190206 ECP_4402 Escherichia coli 536 transporter YjeM YP_672247.1 4614012 D 362663 CDS YP_672248.1 110644518 4190207 complement(4615665..4618988) 1 NC_008253.1 hypothetical protein 4618988 4190207 ECP_4403 Escherichia coli 536 hypothetical protein YP_672248.1 4615665 R 362663 CDS YP_672249.1 110644519 4190208 complement(4619010..4619978) 1 NC_008253.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4619978 psd 4190208 psd Escherichia coli 536 phosphatidylserine decarboxylase YP_672249.1 4619010 R 362663 CDS YP_672250.1 110644520 4190209 complement(4620075..4621160) 1 NC_008253.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4621160 4190209 ECP_4405 Escherichia coli 536 ribosome-associated GTPase YP_672250.1 4620075 R 362663 CDS YP_672251.2 229560203 4190210 4621222..4621767 1 NC_008253.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4621767 4190210 ECP_4406 Escherichia coli 536 oligoribonuclease YP_672251.2 4621222 D 362663 CDS YP_672252.1 110644522 4190211 4621802..4621933 1 NC_008253.1 hypothetical protein 4621933 4190211 ECP_4407 Escherichia coli 536 hypothetical protein YP_672252.1 4621802 D 362663 CDS YP_672253.1 110644523 4191424 complement(4622545..4623684) 1 NC_008253.1 electron transport protein YjeS 4623684 4191424 ECP_4411 Escherichia coli 536 electron transport protein YjeS YP_672253.1 4622545 R 362663 CDS YP_672254.1 110644524 4191425 4623683..4625230 1 NC_008253.1 hypothetical protein 4625230 4191425 ECP_4412 Escherichia coli 536 hypothetical protein YP_672254.1 4623683 D 362663 CDS YP_672255.1 110644525 4191426 4625202..4625663 1 NC_008253.1 possibly involved in cell wall synthesis; ATPase 4625663 4191426 ECP_4413 Escherichia coli 536 ATPase YP_672255.1 4625202 D 362663 CDS YP_672256.1 110644526 4191427 4625682..4627019 1 NC_008253.1 N-acetylmuramoyl-L-alanine amidase 4627019 4191427 ECP_4414 Escherichia coli 536 N-acetylmuramoyl-L-alanine amidase YP_672256.1 4625682 D 362663 CDS YP_672257.1 110644527 4191428 4627029..4628876 1 NC_008253.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4628876 mutL 4191428 mutL Escherichia coli 536 DNA mismatch repair protein YP_672257.1 4627029 D 362663 CDS YP_672258.1 110644528 4191429 4628869..4629819 1 NC_008253.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4629819 miaA 4191429 miaA Escherichia coli 536 tRNA delta(2)-isopentenylpyrophosphate transferase YP_672258.1 4628869 D 362663 CDS YP_672259.1 110644529 4191430 4629905..4630213 1 NC_008253.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4630213 hfq 4191430 hfq Escherichia coli 536 RNA-binding protein Hfq YP_672259.1 4629905 D 362663 CDS YP_672260.1 110644530 4191431 4630289..4631569 1 NC_008253.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4631569 4191431 ECP_4418 Escherichia coli 536 GTPase HflX YP_672260.1 4630289 D 362663 CDS YP_672261.1 110644531 4191432 4631655..4632914 1 NC_008253.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4632914 4191432 ECP_4419 Escherichia coli 536 FtsH protease regulator HflK YP_672261.1 4631655 D 362663 CDS YP_672262.1 110644532 4191433 4632917..4633921 1 NC_008253.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4633921 4191433 ECP_4420 Escherichia coli 536 FtsH protease regulator HflC YP_672262.1 4632917 D 362663 CDS YP_672263.1 110644533 4191434 4634003..4634200 1 NC_008253.1 membrane protein YjeT 4634200 4191434 ECP_4421 Escherichia coli 536 membrane protein YjeT YP_672263.1 4634003 D 362663 CDS YP_672264.1 110644534 4191435 4634304..4635602 1 NC_008253.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4635602 4191435 ECP_4422 Escherichia coli 536 adenylosuccinate synthetase YP_672264.1 4634304 D 362663 CDS YP_672265.1 110644535 4191436 4635807..4636232 1 NC_008253.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4636232 4191436 ECP_4423 Escherichia coli 536 transcriptional repressor NsrR YP_672265.1 4635807 D 362663 CDS YP_672266.1 110644536 4191437 4636271..4638712 1 NC_008253.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4638712 4191437 ECP_4424 Escherichia coli 536 exoribonuclease R YP_672266.1 4636271 D 362663 CDS YP_672267.1 110644537 4191438 4638803..4639534 1 NC_008253.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4639534 4191438 ECP_4425 Escherichia coli 536 23S rRNA (guanosine-2'-O-)-methyltransferase YP_672267.1 4638803 D 362663 CDS YP_672268.1 110644538 4191439 4639661..4640062 1 NC_008253.1 hypothetical protein 4640062 4191439 ECP_4426 Escherichia coli 536 hypothetical protein YP_672268.1 4639661 D 362663 CDS YP_672269.1 110644539 4191440 4640081..4640779 1 NC_008253.1 phage shock protein A 4640779 4191440 ECP_4427 Escherichia coli 536 phage shock protein A YP_672269.1 4640081 D 362663 CDS YP_672270.1 110644540 4191441 4640829..4641488 1 NC_008253.1 hypothetical protein 4641488 4191441 ECP_4428 Escherichia coli 536 hypothetical protein YP_672270.1 4640829 D 362663 CDS YP_672271.1 110644541 4190021 4641506..4641904 1 NC_008253.1 membrane protein YjfL 4641904 4190021 ECP_4429 Escherichia coli 536 membrane protein YjfL YP_672271.1 4641506 D 362663 CDS YP_672272.1 110644542 4190022 4641914..4642552 1 NC_008253.1 hypothetical protein 4642552 4190022 ECP_4430 Escherichia coli 536 hypothetical protein YP_672272.1 4641914 D 362663 CDS YP_672273.1 110644543 4190023 4642555..4643718 1 NC_008253.1 glutathionylspermidine synthase YjfC 4643718 4190023 ECP_4431 Escherichia coli 536 glutathionylspermidine synthase YjfC YP_672273.1 4642555 D 362663 CDS YP_672274.1 110644544 4190024 4643787..4645427 1 NC_008253.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4645427 4190024 ECP_4432 Escherichia coli 536 isovaleryl CoA dehydrogenase YP_672274.1 4643787 D 362663 CDS YP_672275.1 110644545 4190025 complement(4645544..4645831) 1 NC_008253.1 hypothetical protein 4645831 4190025 ECP_4433 Escherichia coli 536 hypothetical protein YP_672275.1 4645544 R 362663 CDS YP_672276.1 110644546 4190026 complement(4645968..4646396) 1 NC_008253.1 hypothetical protein 4646396 4190026 ECP_4434 Escherichia coli 536 hypothetical protein YP_672276.1 4645968 R 362663 CDS YP_672277.1 110644547 4190027 4646479..4647228 1 NC_008253.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4647228 4190027 ECP_4435 Escherichia coli 536 esterase YP_672277.1 4646479 D 362663 CDS YP_672278.1 110644548 4190028 complement(4647225..4647980) 1 NC_008253.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4647980 4190028 ECP_4436 Escherichia coli 536 transcriptional repressor UlaR YP_672278.1 4647225 R 362663 CDS YP_672279.1 110644549 4190029 complement(4648088..4649152) 1 NC_008253.1 L-ascorbate 6-phosphate lactonase 4649152 4190029 ECP_4437 Escherichia coli 536 L-ascorbate 6-phosphate lactonase YP_672279.1 4648088 R 362663 CDS YP_672280.1 110644550 4190030 4649507..4650904 1 NC_008253.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4650904 ulaA 4190030 ulaA Escherichia coli 536 PTS system ascorbate-specific transporter subunit IIC YP_672280.1 4649507 D 362663 CDS YP_672281.1 110644551 4190031 4650920..4651225 1 NC_008253.1 L-ascorbate-specific enzyme IIB component of PTS 4651225 4190031 ECP_4439 Escherichia coli 536 L-ascorbate-specific enzyme IIB component of PTS YP_672281.1 4650920 D 362663 CDS YP_672282.1 110644552 4190032 4651235..4651699 1 NC_008253.1 L-ascorbate-specific enzyme IIA component of PTS 4651699 4190032 ECP_4440 Escherichia coli 536 L-ascorbate-specific enzyme IIA component of PTS YP_672282.1 4651235 D 362663 CDS YP_672283.1 110644553 4190033 4651713..4652363 1 NC_008253.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4652363 ulaD 4190033 ulaD Escherichia coli 536 3-keto-L-gulonate-6-phosphate decarboxylase YP_672283.1 4651713 D 362663 CDS YP_672284.1 110644554 4190034 4652373..4653227 1 NC_008253.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4653227 4190034 ECP_4442 Escherichia coli 536 L-xylulose 5-phosphate 3-epimerase YP_672284.1 4652373 D 362663 CDS YP_672285.1 110644555 4190035 4653227..4653913 1 NC_008253.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4653913 sgaE 4190035 sgaE Escherichia coli 536 L-ribulose-5-phosphate 4-epimerase YP_672285.1 4653227 D 362663 CDS YP_672286.1 110644556 4190036 complement(4654043..4654318) 1 NC_008253.1 hypothetical protein 4654318 4190036 ECP_4444 Escherichia coli 536 hypothetical protein YP_672286.1 4654043 R 362663 CDS YP_672287.1 110644557 4190037 4654737..4655042 1 NC_008253.1 30S ribosomal protein S6 4655042 4190037 ECP_4445 Escherichia coli 536 30S ribosomal protein S6 YP_672287.1 4654737 D 362663 CDS YP_672288.1 110644558 4190038 4655049..4655363 1 NC_008253.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4655363 4190038 ECP_4446 Escherichia coli 536 primosomal replication protein N YP_672288.1 4655049 D 362663 CDS YP_672289.1 110644559 4190039 4655368..4655595 1 NC_008253.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4655595 rpsR 4190039 rpsR Escherichia coli 536 30S ribosomal protein S18 YP_672289.1 4655368 D 362663 CDS YP_672290.1 110644560 4190040 4655637..4656086 1 NC_008253.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4656086 rplI 4190040 rplI Escherichia coli 536 50S ribosomal protein L9 YP_672290.1 4655637 D 362663 CDS YP_672291.1 110644561 4187851 complement(4656197..4656394) 1 NC_008253.1 hypothetical protein 4656394 4187851 ECP_4449 Escherichia coli 536 hypothetical protein YP_672291.1 4656197 R 362663 CDS YP_672292.1 110644562 4187852 4656488..4656979 1 NC_008253.1 hypothetical protein 4656979 4187852 ECP_4450 Escherichia coli 536 hypothetical protein YP_672292.1 4656488 D 362663 CDS YP_672293.1 110644563 4187853 4656982..4657569 1 NC_008253.1 hypothetical protein 4657569 4187853 ECP_4451 Escherichia coli 536 hypothetical protein YP_672293.1 4656982 D 362663 CDS YP_672294.1 110644564 4187854 4657640..4658251 1 NC_008253.1 hypothetical protein 4658251 4187854 ECP_4452 Escherichia coli 536 hypothetical protein YP_672294.1 4657640 D 362663 CDS YP_672295.1 110644565 4187855 complement(4658394..4659671) 1 NC_008253.1 permease 4659671 4187855 ECP_4453 Escherichia coli 536 permease YP_672295.1 4658394 R 362663 CDS YP_672296.1 110644566 4187856 complement(4659764..4661836) 1 NC_008253.1 oxidoreductase 4661836 4187856 ECP_4454 Escherichia coli 536 oxidoreductase YP_672296.1 4659764 R 362663 CDS YP_672297.1 110644567 4187857 complement(4661833..4663374) 1 NC_008253.1 acetyl-CoA:acetoacetyl-CoA transferase subunit beta 4663374 4187857 ECP_4455 Escherichia coli 536 acetyl-CoA:acetoacetyl-CoA transferase subunit beta YP_672297.1 4661833 R 362663 CDS YP_672298.1 110644568 4187858 complement(4663384..4664160) 1 NC_008253.1 3-hydroxybutyryl-CoA dehydratase 4664160 4187858 ECP_4456 Escherichia coli 536 3-hydroxybutyryl-CoA dehydratase YP_672298.1 4663384 R 362663 CDS YP_672299.1 110644569 4187859 complement(4664170..4665012) 1 NC_008253.1 endonuclease 4665012 4187859 ECP_4457 Escherichia coli 536 endonuclease YP_672299.1 4664170 R 362663 CDS YP_672300.1 110644570 4187860 complement(4665022..4665813) 1 NC_008253.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4665813 4187860 ECP_4458 Escherichia coli 536 3-ketoacyl-ACP reductase YP_672300.1 4665022 R 362663 CDS YP_672301.1 110644571 4187861 4666026..4666673 1 NC_008253.1 TetR/AcrR family transcriptional regulator 4666673 4187861 ECP_4459 Escherichia coli 536 TetR/AcrR family transcriptional regulator YP_672301.1 4666026 D 362663 CDS YP_672302.1 110644572 4187862 complement(4666657..4667295) 1 NC_008253.1 membrane protein YtfB 4667295 4187862 ECP_4460 Escherichia coli 536 membrane protein YtfB YP_672302.1 4666657 R 362663 CDS YP_672303.1 110644573 4187863 4667513..4668133 1 NC_008253.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4668133 4187863 ECP_4461 Escherichia coli 536 peptidyl-prolyl cis-trans isomerase YP_672303.1 4667513 D 362663 CDS YP_672304.1 110644574 4187864 4668442..4669854 1 NC_008253.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4669854 4187864 ECP_4462 Escherichia coli 536 D-alanine/D-serine/glycine permease YP_672304.1 4668442 D 362663 CDS YP_672305.1 110644575 4187865 complement(4669899..4670561) 1 NC_008253.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4670561 4187865 ECP_4463 Escherichia coli 536 iron-sulfur cluster repair di-iron protein YP_672305.1 4669899 R 362663 CDS YP_672306.1 110644576 4187866 complement(4670669..4671643) 1 NC_008253.1 membrane protein YtfF 4671643 4187866 ECP_4464 Escherichia coli 536 membrane protein YtfF YP_672306.1 4670669 R 362663 CDS YP_672307.1 110644577 4187867 complement(4671743..4672603) 1 NC_008253.1 hypothetical protein 4672603 4187867 ECP_4465 Escherichia coli 536 hypothetical protein YP_672307.1 4671743 R 362663 CDS YP_672308.1 110644578 4187868 4672692..4673072 1 NC_008253.1 transcriptional regulator YtfH 4673072 4187868 ECP_4466 Escherichia coli 536 transcriptional regulator YtfH YP_672308.1 4672692 D 362663 CDS YP_672309.1 110644579 4187869 complement(4673201..4675144) 1 NC_008253.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4675144 cpdB 4187869 cpdB Escherichia coli 536 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_672309.1 4673201 R 362663 CDS YP_672310.1 110644580 4187887 4675334..4676074 1 NC_008253.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4676074 4187887 ECP_4468 Escherichia coli 536 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_672310.1 4675334 D 362663 CDS YP_672311.1 110644581 4187888 complement(4676064..4676621) 1 NC_008253.1 protein YtfJ 4676621 4187888 ECP_4469 Escherichia coli 536 protein YtfJ YP_672311.1 4676064 R 362663 CDS YP_672312.1 110644582 4187889 4676946..4677152 1 NC_008253.1 hypothetical protein 4677152 4187889 ECP_4470 Escherichia coli 536 hypothetical protein YP_672312.1 4676946 D 362663 CDS YP_672313.1 110644583 4187890 complement(4677230..4678573) 1 NC_008253.1 hypothetical protein 4678573 4187890 ECP_4471 Escherichia coli 536 hypothetical protein YP_672313.1 4677230 R 362663 CDS YP_672314.1 110644584 4187891 complement(4678896..4679534) 1 NC_008253.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4679534 4187891 ECP_4472 Escherichia coli 536 methionine sulfoxide reductase A YP_672314.1 4678896 R 362663 CDS YP_672315.1 110644585 4187892 4679741..4681474 1 NC_008253.1 outer membrane protein 4681474 4187892 ECP_4473 Escherichia coli 536 outer membrane protein YP_672315.1 4679741 D 362663 CDS YP_672316.1 110644586 4187893 4681471..4685250 1 NC_008253.1 hypothetical protein 4685250 4187893 ECP_4474 Escherichia coli 536 hypothetical protein YP_672316.1 4681471 D 362663 CDS YP_672317.1 110644587 4187894 4685253..4685594 1 NC_008253.1 hypothetical protein 4685594 4187894 ECP_4475 Escherichia coli 536 hypothetical protein YP_672317.1 4685253 D 362663 CDS YP_672318.1 110644588 4187895 complement(4685973..4686503) 1 NC_008253.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4686503 4187895 ECP_4476 Escherichia coli 536 inorganic pyrophosphatase YP_672318.1 4685973 R 362663 CDS YP_672319.1 110644589 4187896 4686813..4687769 1 NC_008253.1 ABC transporter substrate-binding protein YtfQ 4687769 4187896 ECP_4477 Escherichia coli 536 ABC transporter substrate-binding protein YtfQ YP_672319.1 4686813 D 362663 CDS YP_672320.1 110644590 4187897 4687909..4689411 1 NC_008253.1 sugar transport system ATP-binding protein 4689411 4187897 ECP_4478 Escherichia coli 536 sugar transport system ATP-binding protein YP_672320.1 4687909 D 362663 CDS YP_672321.1 110644591 4187898 4689425..4690447 1 NC_008253.1 ABC transporter permease 4690447 4187898 ECP_4479 Escherichia coli 536 ABC transporter permease YP_672321.1 4689425 D 362663 CDS YP_672322.1 110644592 4187899 4690434..4691429 1 NC_008253.1 membrane component of a sugar ABC transporter system; ABC transporter permease 4691429 4187899 ECP_4480 Escherichia coli 536 ABC transporter permease YP_672322.1 4690434 D 362663 CDS YP_672323.1 110644593 4187900 complement(4691462..4692460) 1 NC_008253.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4692460 4187900 ECP_4481 Escherichia coli 536 fructose-1,6-bisphosphatase YP_672323.1 4691462 R 362663 CDS YP_672324.1 110644594 4187901 4692636..4694009 1 NC_008253.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4694009 4187901 ECP_4482 Escherichia coli 536 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_672324.1 4692636 D 362663 CDS YP_672325.1 110644595 4187902 complement(4694167..4694718) 1 NC_008253.1 hypothetical protein 4694718 4187902 ECP_4483 Escherichia coli 536 hypothetical protein YP_672325.1 4694167 R 362663 CDS YP_672326.1 110644596 4187903 4694812..4696164 1 NC_008253.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4696164 4187903 ECP_4484 Escherichia coli 536 peptidase PmbA YP_672326.1 4694812 D 362663 CDS YP_672327.1 110644597 4187904 4696347..4696733 1 NC_008253.1 soluble cytochrome 4696733 4187904 ECP_4485 Escherichia coli 536 soluble cytochrome YP_672327.1 4696347 D 362663 CDS YP_672328.1 110644598 4187905 complement(4696778..4697242) 1 NC_008253.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4697242 nrdG 4187905 nrdG Escherichia coli 536 anaerobic ribonucleotide reductase-activating protein YP_672328.1 4696778 R 362663 CDS YP_672329.1 110644599 4187906 complement(4697400..4699538) 1 NC_008253.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4699538 4187906 ECP_4487 Escherichia coli 536 anaerobic ribonucleoside triphosphate reductase YP_672329.1 4697400 R 362663 CDS YP_672330.1 110644600 4188132 complement(4699932..4701587) 1 NC_008253.1 trehalose-6-phosphate hydrolase 4701587 4188132 ECP_4488 Escherichia coli 536 trehalose-6-phosphate hydrolase YP_672330.1 4699932 R 362663 CDS YP_672331.1 110644601 4188133 complement(4701637..4703058) 1 NC_008253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; trehalose(maltose)-specific PTS system components IIBC 4703058 4188133 ECP_4489 Escherichia coli 536 trehalose(maltose)-specific PTS system components IIBC YP_672331.1 4701637 R 362663 CDS YP_672332.1 110644602 4188134 complement(4703177..4704124) 1 NC_008253.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4704124 treR 4188134 treR Escherichia coli 536 trehalose repressor YP_672332.1 4703177 R 362663 CDS YP_672333.1 110644603 4188135 4704129..4704362 1 NC_008253.1 hypothetical protein 4704362 4188135 ECP_4491 Escherichia coli 536 hypothetical protein YP_672333.1 4704129 D 362663 CDS YP_672334.1 110644604 4188136 4704503..4707199 1 NC_008253.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4707199 4188136 ECP_4492 Escherichia coli 536 magnesium-transporting ATPase MgtA YP_672334.1 4704503 D 362663 CDS YP_672335.1 110644605 4188137 complement(4707405..4707791) 1 NC_008253.1 endoribonuclease L-PSP 4707791 4188137 ECP_4493 Escherichia coli 536 endoribonuclease L-PSP YP_672335.1 4707405 R 362663 CDS YP_672336.1 110644606 4188138 complement(4707864..4708325) 1 NC_008253.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 4708325 4188138 ECP_4494 Escherichia coli 536 aspartate carbamoyltransferase YP_672336.1 4707864 R 362663 CDS YP_672337.1 110644607 4188139 complement(4708338..4709273) 1 NC_008253.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 4709273 pyrB 4188139 pyrB Escherichia coli 536 aspartate carbamoyltransferase YP_672337.1 4708338 R 362663 CDS YP_672338.1 110644608 4188140 complement(4709501..4709989) 1 NC_008253.1 arginine repressor 4709989 4188140 ECP_4496 Escherichia coli 536 arginine repressor YP_672338.1 4709501 R 362663 CDS YP_672339.1 110644609 4188141 complement(4710105..4711508) 1 NC_008253.1 C4-dicarboxylate anaerobic carrier 4711508 4188141 ECP_4497 Escherichia coli 536 C4-dicarboxylate anaerobic carrier YP_672339.1 4710105 R 362663 CDS YP_672340.1 110644610 4188142 complement(4711588..4712568) 1 NC_008253.1 ornithine carbamoyltransferase 4712568 4188142 ECP_4498 Escherichia coli 536 ornithine carbamoyltransferase YP_672340.1 4711588 R 362663 CDS YP_672341.1 110644611 4188143 complement(4712579..4713523) 1 NC_008253.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4713523 4188143 ECP_4499 Escherichia coli 536 carbamate kinase YP_672341.1 4712579 R 362663 CDS YP_672342.1 110644612 4188144 complement(4713534..4714754) 1 NC_008253.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 4714754 4188144 ECP_4500 Escherichia coli 536 arginine deiminase YP_672342.1 4713534 R 362663 CDS YP_672343.1 110644613 4188145 4715432..4715884 1 NC_008253.1 hypothetical protein 4715884 4188145 ECP_4501 Escherichia coli 536 hypothetical protein YP_672343.1 4715432 D 362663 CDS YP_672344.1 110644614 4188148 4717096..4717512 1 NC_008253.1 hypothetical protein 4717512 4188148 ECP_4504 Escherichia coli 536 hypothetical protein YP_672344.1 4717096 D 362663 CDS YP_672345.1 110644615 4188569 complement(4717689..4718192) 1 NC_008253.1 acetyltransferase YjgM 4718192 4188569 ECP_4505 Escherichia coli 536 acetyltransferase YjgM YP_672345.1 4717689 R 362663 CDS YP_672346.1 110644616 4188570 4718385..4719572 1 NC_008253.1 membrane protein YjgN 4719572 4188570 ECP_4506 Escherichia coli 536 membrane protein YjgN YP_672346.1 4718385 D 362663 CDS YP_672347.1 110644617 4188571 complement(4719619..4722474) 1 NC_008253.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4722474 valS 4188571 valS Escherichia coli 536 valyl-tRNA synthetase YP_672347.1 4719619 R 362663 CDS YP_672348.1 110644618 4188572 complement(4722474..4722917) 1 NC_008253.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4722917 4188572 ECP_4508 Escherichia coli 536 DNA polymerase III subunit chi YP_672348.1 4722474 R 362663 CDS YP_672349.1 110644619 4188573 complement(4723175..4724686) 1 NC_008253.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4724686 4188573 ECP_4509 Escherichia coli 536 leucyl aminopeptidase YP_672349.1 4723175 R 362663 CDS YP_672350.1 110644620 4188574 4724953..4726053 1 NC_008253.1 membrane protein YjgP 4726053 4188574 ECP_4510 Escherichia coli 536 membrane protein YjgP YP_672350.1 4724953 D 362663 CDS YP_672351.1 110644621 4188575 4726053..4727135 1 NC_008253.1 membrane protein YjgQ 4727135 4188575 ECP_4511 Escherichia coli 536 membrane protein YjgQ YP_672351.1 4726053 D 362663 CDS YP_672352.1 110644622 4188576 complement(4727296..4728798) 1 NC_008253.1 hypothetical protein 4728798 4188576 ECP_4512 Escherichia coli 536 hypothetical protein YP_672352.1 4727296 R 362663 CDS YP_672353.1 110644623 4188577 complement(4728876..4729874) 1 NC_008253.1 L-idonate regulatory protein; HTH-type transcriptional regulator IdnR 4729874 4188577 ECP_4513 Escherichia coli 536 HTH-type transcriptional regulator IdnR YP_672353.1 4728876 R 362663 CDS YP_672354.1 110644624 4188578 complement(4729941..4731260) 1 NC_008253.1 Gnt-II system L-idonate transporter 4731260 4188578 ECP_4514 Escherichia coli 536 Gnt-II system L-idonate transporter YP_672354.1 4729941 R 362663 CDS YP_672355.1 110644625 4188579 complement(4731325..4732089) 1 NC_008253.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4732089 4188579 ECP_4515 Escherichia coli 536 gluconate 5-dehydrogenase YP_672355.1 4731325 R 362663 CDS YP_672356.1 110644626 4188580 complement(4732113..4733144) 1 NC_008253.1 NAD-binding; L-idonate 5-dehydrogenase 4733144 4188580 ECP_4516 Escherichia coli 536 L-idonate 5-dehydrogenase YP_672356.1 4732113 R 362663 CDS YP_672357.1 110644627 4188583 complement(4733932..4734951) 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YjgB 4734951 4188583 ECP_4519 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YjgB YP_672357.1 4733932 R 362663 CDS YP_672358.1 110644628 4188621 4735418..4736680 1 NC_008253.1 prophage P4 integrase 4736680 4188621 ECP_4521 Escherichia coli 536 prophage P4 integrase YP_672358.1 4735418 D 362663 CDS YP_672359.1 110644629 4188622 complement(4736780..4737043) 1 NC_008253.1 hypothetical protein 4737043 4188622 ECP_4522 Escherichia coli 536 hypothetical protein YP_672359.1 4736780 R 362663 CDS YP_672360.1 110644630 4188623 4737132..4740647 1 NC_008253.1 superfamily I DNA helicases 4740647 4188623 ECP_4523 Escherichia coli 536 superfamily I DNA helicases YP_672360.1 4737132 D 362663 CDS YP_672361.1 110644631 4188624 complement(4740756..4742255) 1 NC_008253.1 hypothetical protein 4742255 4188624 ECP_4524 Escherichia coli 536 hypothetical protein YP_672361.1 4740756 R 362663 CDS YP_672362.1 110644632 4188625 complement(4742430..4743170) 1 NC_008253.1 OmpA family protein 4743170 4188625 ECP_4525 Escherichia coli 536 OmpA family protein YP_672362.1 4742430 R 362663 CDS YP_672363.1 110644633 4188626 complement(4743388..4743756) 1 NC_008253.1 hypothetical protein 4743756 4188626 ECP_4526 Escherichia coli 536 hypothetical protein YP_672363.1 4743388 R 362663 CDS YP_672364.1 110644634 4188627 complement(4743857..4744027) 1 NC_008253.1 hypothetical protein 4744027 4188627 ECP_4527 Escherichia coli 536 hypothetical protein YP_672364.1 4743857 R 362663 CDS YP_672365.1 110644635 4188628 complement(4744149..4744322) 1 NC_008253.1 hypothetical protein 4744322 4188628 ECP_4528 Escherichia coli 536 hypothetical protein YP_672365.1 4744149 R 362663 CDS YP_672366.1 110644636 4188629 4744532..4744693 1 NC_008253.1 hypothetical protein 4744693 4188629 ECP_4529 Escherichia coli 536 hypothetical protein YP_672366.1 4744532 D 362663 CDS YP_672367.1 110644637 4188630 complement(4745087..4745302) 1 NC_008253.1 hypothetical protein 4745302 4188630 ECP_4530 Escherichia coli 536 hypothetical protein YP_672367.1 4745087 R 362663 CDS YP_672368.1 110644638 4188631 complement(4745321..4745875) 1 NC_008253.1 PapX protein 4745875 4188631 ECP_4531 Escherichia coli 536 PapX protein YP_672368.1 4745321 R 362663 CDS YP_672369.1 110644639 4188632 complement(4745901..4746134) 1 NC_008253.1 hypothetical protein 4746134 4188632 ECP_4532 Escherichia coli 536 hypothetical protein YP_672369.1 4745901 R 362663 CDS YP_672370.1 110644640 4188633 complement(4746135..4747142) 1 NC_008253.1 protein PapG 4747142 4188633 ECP_4533 Escherichia coli 536 protein PapG YP_672370.1 4746135 R 362663 CDS YP_672371.1 110644641 4188634 complement(4747186..4747689) 1 NC_008253.1 PapF protein 4747689 4188634 ECP_4534 Escherichia coli 536 PapF protein YP_672371.1 4747186 R 362663 CDS YP_672372.1 110644642 4188635 complement(4747764..4748240) 1 NC_008253.1 PapE protein 4748240 4188635 ECP_4535 Escherichia coli 536 PapE protein YP_672372.1 4747764 R 362663 CDS YP_672373.1 110644643 4188636 complement(4748312..4748848) 1 NC_008253.1 PapK fimbrial adapter 4748848 4188636 ECP_4536 Escherichia coli 536 PapK fimbrial adapter YP_672373.1 4748312 R 362663 CDS YP_672374.1 110644644 4188637 complement(4748858..4749439) 1 NC_008253.1 protein PapJ 4749439 4188637 ECP_4537 Escherichia coli 536 protein PapJ YP_672374.1 4748858 R 362663 CDS YP_672375.1 110644645 4188638 complement(4749476..4750210) 1 NC_008253.1 chaperone protein PapD 4750210 4188638 ECP_4538 Escherichia coli 536 chaperone protein PapD YP_672375.1 4749476 R 362663 CDS YP_672376.1 110644646 4188639 complement(4750281..4752803) 1 NC_008253.1 outer membrane usher protein PapC 4752803 4188639 ECP_4539 Escherichia coli 536 outer membrane usher protein PapC YP_672376.1 4750281 R 362663 CDS YP_672377.1 110644647 4188640 complement(4752850..4753437) 1 NC_008253.1 protein PapH 4753437 4188640 ECP_4540 Escherichia coli 536 protein PapH YP_672377.1 4752850 R 362663 CDS YP_672378.1 110644648 4188844 complement(4753507..4754124) 1 NC_008253.1 protein PapA 4754124 4188844 ECP_4541 Escherichia coli 536 protein PapA YP_672378.1 4753507 R 362663 CDS YP_672379.1 110644649 4188845 complement(4754299..4754613) 1 NC_008253.1 major pilu subunit operon regulatory protein PapB 4754613 4188845 ECP_4542 Escherichia coli 536 major pilu subunit operon regulatory protein PapB YP_672379.1 4754299 R 362663 CDS YP_672380.1 110644650 4188846 complement(4754917..4755195) 1 NC_008253.1 hypothetical protein 4755195 4188846 ECP_4543 Escherichia coli 536 hypothetical protein YP_672380.1 4754917 R 362663 CDS YP_672381.1 110644651 4188847 4755317..4755604 1 NC_008253.1 hypothetical protein 4755604 4188847 ECP_4544 Escherichia coli 536 hypothetical protein YP_672381.1 4755317 D 362663 CDS YP_672382.1 110644652 4188848 4755755..4756123 1 NC_008253.1 hypothetical protein 4756123 4188848 ECP_4545 Escherichia coli 536 hypothetical protein YP_672382.1 4755755 D 362663 CDS YP_672383.1 110644653 4188849 4756262..4756471 1 NC_008253.1 hypothetical protein 4756471 4188849 ECP_4546 Escherichia coli 536 hypothetical protein YP_672383.1 4756262 D 362663 CDS YP_672384.1 110644654 4188850 4756629..4756778 1 NC_008253.1 hypothetical protein 4756778 4188850 ECP_4547 Escherichia coli 536 hypothetical protein YP_672384.1 4756629 D 362663 CDS YP_672385.1 110644655 4188851 complement(4756812..4756970) 1 NC_008253.1 hypothetical protein 4756970 4188851 ECP_4548 Escherichia coli 536 hypothetical protein YP_672385.1 4756812 R 362663 CDS YP_672386.1 110644656 4188852 4757034..4757369 1 NC_008253.1 transposase 4757369 4188852 ECP_4549 Escherichia coli 536 transposase YP_672386.1 4757034 D 362663 CDS YP_672387.1 110644657 4188853 4757558..4757989 1 NC_008253.1 transposase 4757989 4188853 ECP_4550 Escherichia coli 536 transposase YP_672387.1 4757558 D 362663 CDS YP_672388.1 110644658 4188854 4758208..4759284 1 NC_008253.1 transposase 4759284 4188854 ECP_4551 Escherichia coli 536 transposase YP_672388.1 4758208 D 362663 CDS YP_672389.1 110644659 4188855 4759367..4759609 1 NC_008253.1 transposase 4759609 4188855 ECP_4552 Escherichia coli 536 transposase YP_672389.1 4759367 D 362663 CDS YP_672390.1 110644660 4188856 complement(4759981..4761417) 1 NC_008253.1 hemolysin D 4761417 4188856 ECP_4553 Escherichia coli 536 hemolysin D YP_672390.1 4759981 R 362663 CDS YP_672391.1 110644661 4188857 complement(4761436..4763559) 1 NC_008253.1 alpha-hemolysin translocation ATP-binding protein HlyB 4763559 4188857 ECP_4554 Escherichia coli 536 alpha-hemolysin translocation ATP-binding protein HlyB YP_672391.1 4761436 R 362663 CDS YP_672392.1 110644662 4188858 complement(4763630..4766704) 1 NC_008253.1 hemolysin A 4766704 4188858 ECP_4555 Escherichia coli 536 hemolysin A YP_672392.1 4763630 R 362663 CDS YP_672393.1 110644663 4188859 complement(4766716..4767228) 1 NC_008253.1 hemolysin-activating lysine-acyltransferase HlyC 4767228 4188859 ECP_4556 Escherichia coli 536 hemolysin-activating lysine-acyltransferase HlyC YP_672393.1 4766716 R 362663 CDS YP_672394.1 110644664 4188860 4767316..4767537 1 NC_008253.1 hypothetical protein 4767537 4188860 ECP_4557 Escherichia coli 536 hypothetical protein YP_672394.1 4767316 D 362663 CDS YP_672395.1 110644665 4188861 complement(4767694..4767897) 1 NC_008253.1 hypothetical protein 4767897 4188861 ECP_4558 Escherichia coli 536 hypothetical protein YP_672395.1 4767694 R 362663 CDS YP_672396.1 110644666 4188862 4768355..4768618 1 NC_008253.1 hypothetical protein 4768618 4188862 ECP_4559 Escherichia coli 536 hypothetical protein YP_672396.1 4768355 D 362663 CDS YP_672397.1 110644667 4188883 complement(4768692..4769462) 1 NC_008253.1 hypothetical protein 4769462 4188883 ECP_4560 Escherichia coli 536 hypothetical protein YP_672397.1 4768692 R 362663 CDS YP_672398.1 110644668 4188884 complement(4769462..4770061) 1 NC_008253.1 hypothetical protein 4770061 4188884 ECP_4561 Escherichia coli 536 hypothetical protein YP_672398.1 4769462 R 362663 CDS YP_672399.1 110644669 4188885 4770202..4770921 1 NC_008253.1 DNA-binding response regulator 4770921 4188885 ECP_4562 Escherichia coli 536 DNA-binding response regulator YP_672399.1 4770202 D 362663 CDS YP_672400.1 110644670 4188886 4770922..4771773 1 NC_008253.1 hypothetical protein 4771773 4188886 ECP_4563 Escherichia coli 536 hypothetical protein YP_672400.1 4770922 D 362663 CDS YP_672401.1 110644671 4188887 4771806..4772393 1 NC_008253.1 histidine kinase-like ATPases 4772393 4188887 ECP_4564 Escherichia coli 536 histidine kinase-like ATPases YP_672401.1 4771806 D 362663 CDS YP_672402.1 110644672 4188888 complement(4772473..4772841) 1 NC_008253.1 transposase-like protein 4772841 4188888 ECP_4565 Escherichia coli 536 transposase-like protein YP_672402.1 4772473 R 362663 CDS YP_672403.1 110644673 4188889 complement(4773155..4773295) 1 NC_008253.1 hypothetical protein 4773295 4188889 ECP_4566 Escherichia coli 536 hypothetical protein YP_672403.1 4773155 R 362663 CDS YP_672404.1 110644674 4188890 complement(4773322..4773642) 1 NC_008253.1 transposase 4773642 4188890 ECP_4567 Escherichia coli 536 transposase YP_672404.1 4773322 R 362663 CDS YP_672405.1 110644675 4188891 complement(4773671..4773937) 1 NC_008253.1 hypothetical protein 4773937 4188891 ECP_4568 Escherichia coli 536 hypothetical protein YP_672405.1 4773671 R 362663 CDS YP_672406.1 110644676 4188892 complement(4774017..4774265) 1 NC_008253.1 hypothetical protein 4774265 4188892 ECP_4569 Escherichia coli 536 hypothetical protein YP_672406.1 4774017 R 362663 CDS YP_672407.1 110644677 4188893 complement(4774618..4776285) 1 NC_008253.1 hypothetical protein 4776285 4188893 ECP_4570 Escherichia coli 536 hypothetical protein YP_672407.1 4774618 R 362663 CDS YP_672408.1 110644678 4188894 complement(4776299..4779259) 1 NC_008253.1 hypothetical protein 4779259 4188894 ECP_4571 Escherichia coli 536 hypothetical protein YP_672408.1 4776299 R 362663 CDS YP_672409.1 110644679 4188895 complement(4779264..4780310) 1 NC_008253.1 modification methylase 4780310 4188895 ECP_4572 Escherichia coli 536 modification methylase YP_672409.1 4779264 R 362663 CDS YP_672410.1 110644680 4188896 complement(4780396..4780575) 1 NC_008253.1 hypothetical protein 4780575 4188896 ECP_4573 Escherichia coli 536 hypothetical protein YP_672410.1 4780396 R 362663 CDS YP_672411.1 110644681 4188897 complement(4780691..4781047) 1 NC_008253.1 hypothetical protein 4781047 4188897 ECP_4574 Escherichia coli 536 hypothetical protein YP_672411.1 4780691 R 362663 CDS YP_672412.1 110644682 4188898 complement(4781057..4781491) 1 NC_008253.1 hypothetical protein 4781491 4188898 ECP_4575 Escherichia coli 536 hypothetical protein YP_672412.1 4781057 R 362663 CDS YP_672413.1 110644683 4188899 complement(4781568..4781903) 1 NC_008253.1 hypothetical protein 4781903 4188899 ECP_4576 Escherichia coli 536 hypothetical protein YP_672413.1 4781568 R 362663 CDS YP_672414.1 110644684 4188900 complement(4781893..4782162) 1 NC_008253.1 hypothetical protein 4782162 4188900 ECP_4577 Escherichia coli 536 hypothetical protein YP_672414.1 4781893 R 362663 CDS YP_672415.1 110644685 4188901 complement(4782205..4782582) 1 NC_008253.1 hypothetical protein 4782582 4188901 ECP_4578 Escherichia coli 536 hypothetical protein YP_672415.1 4782205 R 362663 CDS YP_672416.1 110644686 4188902 complement(4782613..4782999) 1 NC_008253.1 hypothetical protein 4782999 4188902 ECP_4579 Escherichia coli 536 hypothetical protein YP_672416.1 4782613 R 362663 CDS YP_672417.1 110644687 4189068 complement(4782996..4792724) 1 NC_008253.1 hemagglutinin-related protein 4792724 4189068 ECP_4580 Escherichia coli 536 hemagglutinin-related protein YP_672417.1 4782996 R 362663 CDS YP_672418.1 110644688 4189069 complement(4792737..4794503) 1 NC_008253.1 hemolysin activator HlyB 4794503 4189069 ECP_4581 Escherichia coli 536 hemolysin activator HlyB YP_672418.1 4792737 R 362663 CDS YP_672419.1 110644689 4189070 complement(4794562..4794726) 1 NC_008253.1 hypothetical protein 4794726 4189070 ECP_4582 Escherichia coli 536 hypothetical protein YP_672419.1 4794562 R 362663 CDS YP_672420.1 110644690 4189071 complement(4794867..4795100) 1 NC_008253.1 hypothetical protein 4795100 4189071 ECP_4583 Escherichia coli 536 hypothetical protein YP_672420.1 4794867 R 362663 CDS YP_672421.1 110644691 4189072 complement(4795198..4795857) 1 NC_008253.1 hypothetical protein 4795857 4189072 ECP_4584 Escherichia coli 536 hypothetical protein YP_672421.1 4795198 R 362663 CDS YP_672422.1 110644692 4189073 complement(4796089..4796637) 1 NC_008253.1 hypothetical protein 4796637 4189073 ECP_4585 Escherichia coli 536 hypothetical protein YP_672422.1 4796089 R 362663 CDS YP_672424.1 110644694 4189075 complement(4796904..4797218) 1 NC_008253.1 hypothetical protein 4797218 4189075 ECP_4587 Escherichia coli 536 hypothetical protein YP_672424.1 4796904 R 362663 CDS YP_672425.1 110644695 4189076 complement(4797206..4797898) 1 NC_008253.1 hypothetical protein 4797898 4189076 ECP_4588 Escherichia coli 536 hypothetical protein YP_672425.1 4797206 R 362663 CDS YP_672426.1 110644696 4189077 complement(4798013..4798579) 1 NC_008253.1 hypothetical protein 4798579 4189077 ECP_4589 Escherichia coli 536 hypothetical protein YP_672426.1 4798013 R 362663 CDS YP_672427.1 110644697 4189078 complement(4799690..4801018) 1 NC_008253.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 4801018 4189078 ECP_4590 Escherichia coli 536 D-serine dehydratase YP_672427.1 4799690 R 362663 CDS YP_672428.1 110644698 4189079 complement(4801036..4802373) 1 NC_008253.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 4802373 4189079 ECP_4591 Escherichia coli 536 permease DsdX YP_672428.1 4801036 R 362663 CDS YP_672429.1 110644699 4189080 4802585..4803535 1 NC_008253.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 4803535 4189080 ECP_4592 Escherichia coli 536 DNA-binding transcriptional regulator DsdC YP_672429.1 4802585 D 362663 CDS YP_672430.1 110644700 4189081 4803604..4803948 1 NC_008253.1 IS orf 4803948 4189081 ECP_4593 Escherichia coli 536 IS orf YP_672430.1 4803604 D 362663 CDS YP_672431.1 110644701 4189082 complement(4804188..4804517) 1 NC_008253.1 quaternary ammonium compound-resistance protein QacE 4804517 4189082 ECP_4594 Escherichia coli 536 quaternary ammonium compound-resistance protein QacE YP_672431.1 4804188 R 362663 CDS YP_672432.1 110644702 4189083 complement(4804533..4804934) 1 NC_008253.1 quaternary ammonium compound-resistance protein QacE 4804934 4189083 ECP_4595 Escherichia coli 536 quaternary ammonium compound-resistance protein QacE YP_672432.1 4804533 R 362663 CDS YP_672433.1 110644703 4189084 complement(4804967..4805632) 1 NC_008253.1 hypothetical protein 4805632 4189084 ECP_4596 Escherichia coli 536 hypothetical protein YP_672433.1 4804967 R 362663 CDS YP_672434.1 110644704 4189085 complement(4805644..4806264) 1 NC_008253.1 hypothetical protein 4806264 4189085 ECP_4597 Escherichia coli 536 hypothetical protein YP_672434.1 4805644 R 362663 CDS YP_672435.1 110644705 4189086 complement(4806261..4806725) 1 NC_008253.1 hypothetical protein 4806725 4189086 ECP_4598 Escherichia coli 536 hypothetical protein YP_672435.1 4806261 R 362663 CDS YP_672436.1 110644706 4189469 complement(4806737..4807684) 1 NC_008253.1 hypothetical protein 4807684 4189469 ECP_4599 Escherichia coli 536 hypothetical protein YP_672436.1 4806737 R 362663 CDS YP_672437.1 110644707 4189470 complement(4807736..4811158) 1 NC_008253.1 hypothetical protein 4811158 4189470 ECP_4600 Escherichia coli 536 hypothetical protein YP_672437.1 4807736 R 362663 CDS YP_672438.1 110644708 4189471 complement(4811149..4812315) 1 NC_008253.1 hypothetical protein 4812315 4189471 ECP_4601 Escherichia coli 536 hypothetical protein YP_672438.1 4811149 R 362663 CDS YP_672439.1 110644709 4189472 complement(4812319..4812576) 1 NC_008253.1 hypothetical protein 4812576 4189472 ECP_4602 Escherichia coli 536 hypothetical protein YP_672439.1 4812319 R 362663 CDS YP_672440.1 110644710 4189473 complement(4812603..4814189) 1 NC_008253.1 hypothetical protein 4814189 4189473 ECP_4603 Escherichia coli 536 hypothetical protein YP_672440.1 4812603 R 362663 CDS YP_672441.1 110644711 4189474 complement(4814243..4814521) 1 NC_008253.1 hypothetical protein 4814521 4189474 ECP_4604 Escherichia coli 536 hypothetical protein YP_672441.1 4814243 R 362663 CDS YP_672442.1 110644712 4189475 complement(4814536..4814820) 1 NC_008253.1 hypothetical protein 4814820 4189475 ECP_4605 Escherichia coli 536 hypothetical protein YP_672442.1 4814536 R 362663 CDS YP_672443.1 110644713 4189476 complement(4814838..4815167) 1 NC_008253.1 hypothetical protein 4815167 4189476 ECP_4606 Escherichia coli 536 hypothetical protein YP_672443.1 4814838 R 362663 CDS YP_672444.1 110644714 4189477 4815372..4815557 1 NC_008253.1 hypothetical protein 4815557 4189477 ECP_4607 Escherichia coli 536 hypothetical protein YP_672444.1 4815372 D 362663 CDS YP_672445.1 110644715 4189478 complement(4815636..4816154) 1 NC_008253.1 hypothetical protein 4816154 4189478 ECP_4608 Escherichia coli 536 hypothetical protein YP_672445.1 4815636 R 362663 CDS YP_672446.1 110644716 4189479 complement(4816154..4816972) 1 NC_008253.1 hypothetical protein 4816972 4189479 ECP_4609 Escherichia coli 536 hypothetical protein YP_672446.1 4816154 R 362663 CDS YP_672447.1 110644717 4189480 complement(4816995..4817573) 1 NC_008253.1 transcription regulator protein 4817573 4189480 ECP_4610 Escherichia coli 536 transcription regulator protein YP_672447.1 4816995 R 362663 CDS YP_672448.1 110644718 4189481 complement(4817864..4818754) 1 NC_008253.1 transposase OrfB protein of insertion sequence IS629 4818754 4189481 ECP_4611 Escherichia coli 536 transposase OrfB protein of insertion sequence IS629 YP_672448.1 4817864 R 362663 CDS YP_672449.1 110644719 4189482 complement(4818751..4819077) 1 NC_008253.1 transposase OrfA protein of insertion sequence IS629 4819077 4189482 ECP_4612 Escherichia coli 536 transposase OrfA protein of insertion sequence IS629 YP_672449.1 4818751 R 362663 CDS YP_672450.1 110644720 4189483 4819211..4819429 1 NC_008253.1 hypothetical protein 4819429 4189483 ECP_4613 Escherichia coli 536 hypothetical protein YP_672450.1 4819211 D 362663 CDS YP_672451.1 110644721 4189484 4819437..4820729 1 NC_008253.1 aminotransferase 4820729 4189484 ECP_4614 Escherichia coli 536 aminotransferase YP_672451.1 4819437 D 362663 CDS YP_672452.1 110644722 4189485 4820674..4821912 1 NC_008253.1 Na+/H+ antiporter 4821912 4189485 ECP_4615 Escherichia coli 536 Na+/H+ antiporter YP_672452.1 4820674 D 362663 CDS YP_672453.1 110644723 4189486 complement(4821922..4822704) 1 NC_008253.1 transposase/IS protein 4822704 4189486 ECP_4616 Escherichia coli 536 transposase/IS protein YP_672453.1 4821922 R 362663 CDS YP_672454.1 110644724 4189487 complement(4822701..4823723) 1 NC_008253.1 transposase 4823723 4189487 ECP_4617 Escherichia coli 536 transposase YP_672454.1 4822701 R 362663 CDS YP_672455.1 110644725 4189488 4823776..4824132 1 NC_008253.1 Na+/H+ antiporter 4824132 4189488 ECP_4618 Escherichia coli 536 Na+/H+ antiporter YP_672455.1 4823776 D 362663 CDS YP_672456.1 110644726 4189585 4824756..4824935 1 NC_008253.1 transposase 4824935 4189585 ECP_4619 Escherichia coli 536 transposase YP_672456.1 4824756 D 362663 CDS YP_672457.1 110644727 4189586 4824932..4825411 1 NC_008253.1 hypothetical protein 4825411 4189586 ECP_4620 Escherichia coli 536 hypothetical protein YP_672457.1 4824932 D 362663 CDS YP_672458.1 110644728 4189587 complement(4825446..4826324) 1 NC_008253.1 hypothetical protein 4826324 4189587 ECP_4621 Escherichia coli 536 hypothetical protein YP_672458.1 4825446 R 362663 CDS YP_672459.1 110644729 4189588 complement(4826652..4827383) 1 NC_008253.1 hypothetical protein 4827383 4189588 ECP_4622 Escherichia coli 536 hypothetical protein YP_672459.1 4826652 R 362663 CDS YP_672460.1 110644730 4189589 complement(4827427..4827621) 1 NC_008253.1 hypothetical protein 4827621 4189589 ECP_4623 Escherichia coli 536 hypothetical protein YP_672460.1 4827427 R 362663 CDS YP_672461.1 110644731 4189590 complement(4827805..4828041) 1 NC_008253.1 hypothetical protein 4828041 4189590 ECP_4624 Escherichia coli 536 hypothetical protein YP_672461.1 4827805 R 362663 CDS YP_672462.1 110644732 4189591 complement(4828866..4830089) 1 NC_008253.1 hypothetical protein 4830089 4189591 ECP_4625 Escherichia coli 536 hypothetical protein YP_672462.1 4828866 R 362663 CDS YP_672463.1 110644733 4189592 4830190..4831074 1 NC_008253.1 hypothetical protein 4831074 4189592 ECP_4626 Escherichia coli 536 hypothetical protein YP_672463.1 4830190 D 362663 CDS YP_672464.1 110644734 4189593 4831277..4831957 1 NC_008253.1 hypothetical protein 4831957 4189593 ECP_4627 Escherichia coli 536 hypothetical protein YP_672464.1 4831277 D 362663 CDS YP_672465.1 110644735 4189594 4832000..4832782 1 NC_008253.1 hypothetical protein 4832782 4189594 ECP_4628 Escherichia coli 536 hypothetical protein YP_672465.1 4832000 D 362663 CDS YP_672466.1 110644736 4189595 4833111..4833929 1 NC_008253.1 hypothetical protein 4833929 4189595 ECP_4629 Escherichia coli 536 hypothetical protein YP_672466.1 4833111 D 362663 CDS YP_672467.1 110644737 4189596 4834062..4834505 1 NC_008253.1 hypothetical protein 4834505 4189596 ECP_4630 Escherichia coli 536 hypothetical protein YP_672467.1 4834062 D 362663 CDS YP_672468.1 110644738 4189597 4834520..4834996 1 NC_008253.1 DNA repair protein 4834996 4189597 ECP_4631 Escherichia coli 536 DNA repair protein YP_672468.1 4834520 D 362663 CDS YP_672469.1 110644739 4189598 4835083..4835304 1 NC_008253.1 hypothetical protein 4835304 4189598 ECP_4632 Escherichia coli 536 hypothetical protein YP_672469.1 4835083 D 362663 CDS YP_672470.1 110644740 4189599 4835384..4835752 1 NC_008253.1 hypothetical protein 4835752 4189599 ECP_4633 Escherichia coli 536 hypothetical protein YP_672470.1 4835384 D 362663 CDS YP_672471.1 110644741 4189600 4835842..4836219 1 NC_008253.1 hypothetical protein 4836219 4189600 ECP_4634 Escherichia coli 536 hypothetical protein YP_672471.1 4835842 D 362663 CDS YP_672472.1 110644742 4189601 4836270..4836704 1 NC_008253.1 hypothetical protein 4836704 4189601 ECP_4635 Escherichia coli 536 hypothetical protein YP_672472.1 4836270 D 362663 CDS YP_672473.1 110644743 4189602 4836671..4836913 1 NC_008253.1 hypothetical protein 4836913 4189602 ECP_4636 Escherichia coli 536 hypothetical protein YP_672473.1 4836671 D 362663 CDS YP_672474.1 110644744 4189603 4836992..4837150 1 NC_008253.1 hypothetical protein 4837150 4189603 ECP_4637 Escherichia coli 536 hypothetical protein YP_672474.1 4836992 D 362663 CDS YP_672475.1 110644745 4190215 4837169..4837606 1 NC_008253.1 hypothetical protein 4837606 4190215 ECP_4638 Escherichia coli 536 hypothetical protein YP_672475.1 4837169 D 362663 CDS YP_672476.1 110644746 4190216 4838090..4840138 1 NC_008253.1 hypothetical protein 4840138 4190216 ECP_4639 Escherichia coli 536 hypothetical protein YP_672476.1 4838090 D 362663 CDS YP_672477.1 110644747 4190217 complement(4840537..4840716) 1 NC_008253.1 hypothetical protein 4840716 4190217 ECP_4640 Escherichia coli 536 hypothetical protein YP_672477.1 4840537 R 362663 CDS YP_672478.1 110644748 4190218 complement(4840761..4841633) 1 NC_008253.1 hypothetical protein 4841633 4190218 ECP_4641 Escherichia coli 536 hypothetical protein YP_672478.1 4840761 R 362663 CDS YP_672479.1 110644749 4190219 complement(4841845..4842825) 1 NC_008253.1 hypothetical protein 4842825 4190219 ECP_4642 Escherichia coli 536 hypothetical protein YP_672479.1 4841845 R 362663 CDS YP_672480.1 110644750 4190220 complement(4842890..4843996) 1 NC_008253.1 hypothetical protein 4843996 4190220 ECP_4643 Escherichia coli 536 hypothetical protein YP_672480.1 4842890 R 362663 CDS YP_672481.1 110644751 4190221 complement(4844016..4844732) 1 NC_008253.1 hypothetical protein 4844732 4190221 ECP_4644 Escherichia coli 536 hypothetical protein YP_672481.1 4844016 R 362663 CDS YP_672482.1 110644752 4190222 complement(4845529..4845807) 1 NC_008253.1 hypothetical protein 4845807 4190222 ECP_4645 Escherichia coli 536 hypothetical protein YP_672482.1 4845529 R 362663 CDS YP_672483.1 110644753 4190223 4846196..4846798 1 NC_008253.1 inversion of on/off regulator of fimA; tyrosine recombinase 4846798 4190223 ECP_4646 Escherichia coli 536 tyrosine recombinase YP_672483.1 4846196 D 362663 CDS YP_672484.1 110644754 4190224 4847276..4847872 1 NC_008253.1 inversion of on/off regulator of fimA; tyrosine recombinase 4847872 4190224 ECP_4647 Escherichia coli 536 tyrosine recombinase YP_672484.1 4847276 D 362663 CDS YP_672485.1 110644755 4190225 complement(4847951..4848166) 1 NC_008253.1 hypothetical protein 4848166 4190225 ECP_4648 Escherichia coli 536 hypothetical protein YP_672485.1 4847951 R 362663 CDS YP_672486.1 110644756 4190226 4848353..4848901 1 NC_008253.1 type-1 fimbrial major subunit 4848901 4190226 ECP_4649 Escherichia coli 536 type-1 fimbrial major subunit YP_672486.1 4848353 D 362663 CDS YP_672487.1 110644757 4190227 4848867..4849505 1 NC_008253.1 fimbrin-like protein fimI 4849505 4190227 ECP_4650 Escherichia coli 536 fimbrin-like protein fimI YP_672487.1 4848867 D 362663 CDS YP_672488.1 110644758 4190228 4849611..4850267 1 NC_008253.1 chaperone protein FimC 4850267 4190228 ECP_4651 Escherichia coli 536 chaperone protein FimC YP_672488.1 4849611 D 362663 CDS YP_672489.1 110644759 4190229 4850333..4852969 1 NC_008253.1 outer membrane usher protein FimD 4852969 4190229 ECP_4652 Escherichia coli 536 outer membrane usher protein FimD YP_672489.1 4850333 D 362663 CDS YP_672490.1 110644760 4190230 4852979..4853509 1 NC_008253.1 FimF protein 4853509 4190230 ECP_4653 Escherichia coli 536 FimF protein YP_672490.1 4852979 D 362663 CDS YP_672491.1 110644761 4190231 4853522..4854025 1 NC_008253.1 FimG protein 4854025 4190231 ECP_4654 Escherichia coli 536 FimG protein YP_672491.1 4853522 D 362663 CDS YP_672492.1 110644762 4190232 4854036..4854947 1 NC_008253.1 FimH protein 4854947 4190232 ECP_4655 Escherichia coli 536 FimH protein YP_672492.1 4854036 D 362663 CDS YP_672493.1 110644763 4190233 4855257..4855391 1 NC_008253.1 hypothetical protein 4855391 4190233 ECP_4656 Escherichia coli 536 hypothetical protein YP_672493.1 4855257 D 362663 CDS YP_672494.1 110644764 4190234 4855494..4855649 1 NC_008253.1 hypothetical protein 4855649 4190234 ECP_4657 Escherichia coli 536 hypothetical protein YP_672494.1 4855494 D 362663 CDS YP_672495.1 110644765 4190557 4855676..4856860 1 NC_008253.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4856860 4190557 ECP_4658 Escherichia coli 536 mannonate dehydratase YP_672495.1 4855676 D 362663 CDS YP_672496.1 110644766 4190558 4856941..4858401 1 NC_008253.1 D-mannonate oxidoreductase 4858401 4190558 ECP_4659 Escherichia coli 536 D-mannonate oxidoreductase YP_672496.1 4856941 D 362663 CDS YP_672497.1 110644767 4190559 4858616..4859389 1 NC_008253.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4859389 4190559 ECP_4660 Escherichia coli 536 DNA-binding transcriptional repressor UxuR YP_672497.1 4858616 D 362663 CDS YP_672498.1 110644768 4190560 4859803..4860186 1 NC_008253.1 hypothetical protein 4860186 4190560 ECP_4661 Escherichia coli 536 hypothetical protein YP_672498.1 4859803 D 362663 CDS YP_672499.1 110644769 4190561 complement(4860234..4860575) 1 NC_008253.1 hypothetical protein 4860575 4190561 ECP_4662 Escherichia coli 536 hypothetical protein YP_672499.1 4860234 R 362663 CDS YP_672500.1 110644770 4190562 complement(4860612..4861568) 1 NC_008253.1 DNA-binding transcriptional regulator 4861568 4190562 ECP_4663 Escherichia coli 536 DNA-binding transcriptional regulator YP_672500.1 4860612 R 362663 CDS YP_672501.1 110644771 4190563 complement(4861588..4862760) 1 NC_008253.1 isoaspartyl dipeptidase 4862760 4190563 ECP_4664 Escherichia coli 536 isoaspartyl dipeptidase YP_672501.1 4861588 R 362663 CDS YP_672502.1 110644772 4190564 complement(4862773..4863234) 1 NC_008253.1 hypothetical protein 4863234 4190564 ECP_4665 Escherichia coli 536 hypothetical protein YP_672502.1 4862773 R 362663 CDS YP_672503.1 110644773 4190565 complement(4863231..4863914) 1 NC_008253.1 hypothetical protein 4863914 4190565 ECP_4666 Escherichia coli 536 hypothetical protein YP_672503.1 4863231 R 362663 CDS YP_672504.1 110644774 4190566 4864164..4864718 1 NC_008253.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4864718 4190566 ECP_4667 Escherichia coli 536 RNA 2'-phosphotransferase-like protein YP_672504.1 4864164 D 362663 CDS YP_672505.1 110644775 4190567 complement(4864731..4865909) 1 NC_008253.1 hypothetical protein 4865909 4190567 ECP_4668 Escherichia coli 536 hypothetical protein YP_672505.1 4864731 R 362663 CDS YP_672506.1 110644776 4190568 complement(4865977..4866945) 1 NC_008253.1 hypothetical protein 4866945 4190568 ECP_4669 Escherichia coli 536 hypothetical protein YP_672506.1 4865977 R 362663 CDS YP_672507.1 110644777 4190569 complement(4867156..4867923) 1 NC_008253.1 R-phenyllactate dehydratase activator 4867923 4190569 ECP_4670 Escherichia coli 536 R-phenyllactate dehydratase activator YP_672507.1 4867156 R 362663 CDS YP_672508.1 110644778 4190570 complement(4867933..4869084) 1 NC_008253.1 hypothetical protein 4869084 4190570 ECP_4671 Escherichia coli 536 hypothetical protein YP_672508.1 4867933 R 362663 CDS YP_672509.1 110644779 4190571 complement(4869200..4870480) 1 NC_008253.1 hypothetical protein 4870480 4190571 ECP_4672 Escherichia coli 536 hypothetical protein YP_672509.1 4869200 R 362663 CDS YP_672510.1 110644780 4190572 4870665..4871585 1 NC_008253.1 hypothetical protein 4871585 4190572 ECP_4673 Escherichia coli 536 hypothetical protein YP_672510.1 4870665 D 362663 CDS YP_672511.1 110644781 4190573 4871883..4874084 1 NC_008253.1 hypothetical protein 4874084 4190573 ECP_4674 Escherichia coli 536 hypothetical protein YP_672511.1 4871883 D 362663 CDS YP_672512.1 110644782 4190574 complement(4874131..4874472) 1 NC_008253.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 4874472 4190574 ECP_4675 Escherichia coli 536 endoribonuclease SymE YP_672512.1 4874131 R 362663 CDS YP_672513.1 110644783 4190575 complement(4874693..4876399) 1 NC_008253.1 type I restriction enzyme EcoEI specificity protein 4876399 4190575 ECP_4676 Escherichia coli 536 type I restriction enzyme EcoEI specificity protein YP_672513.1 4874693 R 362663 CDS YP_672514.1 110644784 4190576 complement(4876399..4877904) 1 NC_008253.1 type I restriction enzyme EcoEI M protein 4877904 4190576 ECP_4677 Escherichia coli 536 type I restriction enzyme EcoEI M protein YP_672514.1 4876399 R 362663 CDS YP_672515.1 110644785 4190577 complement(4877935..4880367) 1 NC_008253.1 type I restriction enzyme EcoAI R protein 4880367 4190577 ECP_4678 Escherichia coli 536 type I restriction enzyme EcoAI R protein YP_672515.1 4877935 R 362663 CDS YP_672516.1 110644786 4190578 4880645..4882297 1 NC_008253.1 hypothetical protein 4882297 4190578 ECP_4679 Escherichia coli 536 hypothetical protein YP_672516.1 4880645 D 362663 CDS YP_672517.1 110644787 4190579 complement(4882366..4883322) 1 NC_008253.1 GTP-binding protein YjiA 4883322 4190579 ECP_4680 Escherichia coli 536 GTP-binding protein YjiA YP_672517.1 4882366 R 362663 CDS YP_672518.1 110644788 4190580 complement(4883333..4883536) 1 NC_008253.1 hypothetical protein 4883536 4190580 ECP_4681 Escherichia coli 536 hypothetical protein YP_672518.1 4883333 R 362663 CDS YP_672519.1 110644789 4190581 complement(4883654..4885804) 1 NC_008253.1 carbon starvation protein 4885804 4190581 ECP_4682 Escherichia coli 536 carbon starvation protein YP_672519.1 4883654 R 362663 CDS YP_672520.1 110644790 4190582 4886181..4887845 1 NC_008253.1 serine chemoreceptorprotein; methyl-accepting chemotaxis protein I 4887845 4190582 ECP_4683 Escherichia coli 536 methyl-accepting chemotaxis protein I YP_672520.1 4886181 D 362663 CDS YP_672521.1 110644791 4190583 complement(4887888..4889159) 1 NC_008253.1 C4-dicarboxylate transporter large subunit 4889159 4190583 ECP_4684 Escherichia coli 536 C4-dicarboxylate transporter large subunit YP_672521.1 4887888 R 362663 CDS YP_672522.1 110644792 4190584 complement(4889156..4889629) 1 NC_008253.1 C4-dicarboxylate transporter small subunit 4889629 4190584 ECP_4685 Escherichia coli 536 C4-dicarboxylate transporter small subunit YP_672522.1 4889156 R 362663 CDS YP_672523.1 110644793 4190585 complement(4889693..4890664) 1 NC_008253.1 C4-dicarboxylate-binding protein 4890664 4190585 ECP_4686 Escherichia coli 536 C4-dicarboxylate-binding protein YP_672523.1 4889693 R 362663 CDS YP_672524.1 110644794 4190586 4891334..4893007 1 NC_008253.1 Na(+)/H(+) exchanger YjcE 4893007 4190586 ECP_4687 Escherichia coli 536 Na(+)/H(+) exchanger YjcE YP_672524.1 4891334 D 362663 CDS YP_672525.1 110644795 4190587 complement(4893178..4894083) 1 NC_008253.1 hypothetical protein 4894083 4190587 ECP_4688 Escherichia coli 536 hypothetical protein YP_672525.1 4893178 R 362663 CDS YP_672526.1 110644796 4190588 4894222..4895244 1 NC_008253.1 zinc-type alcohol dehydrogenase-like protein YjjN 4895244 4190588 ECP_4689 Escherichia coli 536 zinc-type alcohol dehydrogenase-like protein YjjN YP_672526.1 4894222 D 362663 CDS YP_672527.1 110644797 4190589 complement(4895384..4897675) 1 NC_008253.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4897675 4190589 ECP_4690 Escherichia coli 536 phosphoglycerol transferase I YP_672527.1 4895384 R 362663 CDS YP_672528.1 110644798 4190590 complement(4897929..4898426) 1 NC_008253.1 hypothetical protein 4898426 4190590 ECP_4691 Escherichia coli 536 hypothetical protein YP_672528.1 4897929 R 362663 CDS YP_672529.1 110644799 4190591 complement(4898472..4899209) 1 NC_008253.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4899209 4190591 ECP_4692 Escherichia coli 536 DNA replication protein DnaC YP_672529.1 4898472 R 362663 CDS YP_672530.1 110644800 4190592 complement(4899212..4899751) 1 NC_008253.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4899751 4190592 ECP_4693 Escherichia coli 536 primosomal protein DnaI YP_672530.1 4899212 R 362663 CDS YP_672531.1 110644801 4190593 complement(4899859..4900332) 1 NC_008253.1 hypothetical protein 4900332 4190593 ECP_4694 Escherichia coli 536 hypothetical protein YP_672531.1 4899859 R 362663 CDS YP_672532.1 110644802 4190594 complement(4900323..4901093) 1 NC_008253.1 hypothetical protein 4901093 4190594 ECP_4695 Escherichia coli 536 hypothetical protein YP_672532.1 4900323 R 362663 CDS YP_672533.1 110644803 4190595 4901788..4902438 1 NC_008253.1 LuxR family transcriptional regulator 4902438 4190595 ECP_4696 Escherichia coli 536 LuxR family transcriptional regulator YP_672533.1 4901788 D 362663 CDS YP_672534.1 110644804 4190646 4902546..4903073 1 NC_008253.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4903073 4190646 ECP_4697 Escherichia coli 536 DNA-binding transcriptional activator BglJ YP_672534.1 4902546 D 362663 CDS YP_672535.1 110644805 4190647 complement(4903111..4903899) 1 NC_008253.1 ferric hydroximate transport ferric iron reductase 4903899 4190647 ECP_4698 Escherichia coli 536 ferric hydroximate transport ferric iron reductase YP_672535.1 4903111 R 362663 CDS YP_672536.1 110644806 4190648 4904001..4904276 1 NC_008253.1 hypothetical protein 4904276 4190648 ECP_4699 Escherichia coli 536 hypothetical protein YP_672536.1 4904001 D 362663 CDS YP_672537.1 110644807 4190940 complement(4904837..4905868) 1 NC_008253.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4905868 rsmC 4190940 rsmC Escherichia coli 536 16S ribosomal RNA m2G1207 methyltransferase YP_672537.1 4904837 R 362663 CDS YP_672538.1 110644808 4190941 4905971..4906384 1 NC_008253.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4906384 4190941 ECP_4755 Escherichia coli 536 DNA polymerase III subunit psi YP_672538.1 4905971 D 362663 CDS YP_672539.1 110644809 4190942 4906353..4906799 1 NC_008253.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4906799 rimI 4190942 rimI Escherichia coli 536 ribosomal-protein-alanine N-acetyltransferase YP_672539.1 4906353 D 362663 CDS YP_672540.1 110644810 4190943 4906814..4907491 1 NC_008253.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4907491 4190943 ECP_4757 Escherichia coli 536 nucleotidase YP_672540.1 4906814 D 362663 CDS YP_672541.1 110644811 4189659 4907555..4909171 1 NC_008253.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4909171 prfC 4189659 prfC Escherichia coli 536 peptide chain release factor 3 YP_672541.1 4907555 D 362663 CDS YP_672542.1 110644812 4189660 4909564..4910169 1 NC_008253.1 hypothetical protein 4910169 4189660 ECP_4759 Escherichia coli 536 hypothetical protein YP_672542.1 4909564 D 362663 CDS YP_672543.1 110644813 4189661 4910296..4910457 1 NC_008253.1 hypothetical protein 4910457 4189661 ECP_4760 Escherichia coli 536 hypothetical protein YP_672543.1 4910296 D 362663 CDS YP_672544.1 110644814 4189662 4910579..4911652 1 NC_008253.1 hypothetical protein 4911652 4189662 ECP_4761 Escherichia coli 536 hypothetical protein YP_672544.1 4910579 D 362663 CDS YP_672545.1 110644815 4189663 4911649..4912428 1 NC_008253.1 deoxyribonuclease YjjV 4912428 4189663 ECP_4762 Escherichia coli 536 deoxyribonuclease YjjV YP_672545.1 4911649 D 362663 CDS YP_672546.1 110644816 4189664 complement(4912645..4913508) 1 NC_008253.1 hypothetical protein 4913508 4189664 ECP_4763 Escherichia coli 536 hypothetical protein YP_672546.1 4912645 R 362663 CDS YP_672547.1 110644817 4189665 complement(4913480..4915030) 1 NC_008253.1 hypothetical protein 4915030 4189665 ECP_4764 Escherichia coli 536 hypothetical protein YP_672547.1 4913480 R 362663 CDS YP_672548.1 110644818 4189666 4915288..4916067 1 NC_008253.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4916067 4189666 ECP_4765 Escherichia coli 536 deoxyribose-phosphate aldolase YP_672548.1 4915288 D 362663 CDS YP_672549.1 110644819 4189667 4916094..4917467 1 NC_008253.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4917467 deoA 4189667 deoA Escherichia coli 536 thymidine phosphorylase YP_672549.1 4916094 D 362663 CDS YP_672550.1 110644820 4189668 4917519..4918742 1 NC_008253.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4918742 4189668 ECP_4767 Escherichia coli 536 phosphopentomutase YP_672550.1 4917519 D 362663 CDS YP_672551.1 110644821 4189669 4918799..4919518 1 NC_008253.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4919518 deoD 4189669 deoD Escherichia coli 536 purine nucleoside phosphorylase YP_672551.1 4918799 D 362663 CDS YP_672552.1 110644822 4189670 complement(4919700..4919942) 1 NC_008253.1 hypothetical protein 4919942 4189670 ECP_4769 Escherichia coli 536 hypothetical protein YP_672552.1 4919700 R 362663 CDS YP_672553.1 110644823 4189671 complement(4919974..4920990) 1 NC_008253.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4920990 lplA 4189671 lplA Escherichia coli 536 lipoate-protein ligase A YP_672553.1 4919974 R 362663 CDS YP_672554.1 110644824 4189672 complement(4921018..4921662) 1 NC_008253.1 hypothetical protein 4921662 4189672 ECP_4771 Escherichia coli 536 hypothetical protein YP_672554.1 4921018 R 362663 CDS YP_672555.1 110644825 4189673 4921768..4922736 1 NC_008253.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4922736 serB 4189673 serB Escherichia coli 536 phosphoserine phosphatase YP_672555.1 4921768 D 362663 CDS YP_672556.1 110644826 4189674 4922785..4924167 1 NC_008253.1 DNA repair protein sms; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4924167 4189674 ECP_4773 Escherichia coli 536 DNA repair protein RadA YP_672556.1 4922785 D 362663 CDS YP_672557.1 110644827 4189675 4924188..4925420 1 NC_008253.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4925420 4189675 ECP_4774 Escherichia coli 536 nicotinamide-nucleotide adenylyltransferase YP_672557.1 4924188 D 362663 CDS YP_672558.1 110644828 4189676 4925545..4925844 1 NC_008253.1 hypothetical protein 4925844 4189676 ECP_4775 Escherichia coli 536 hypothetical protein YP_672558.1 4925545 D 362663 CDS YP_672559.1 110644829 4189677 4925846..4926130 1 NC_008253.1 MerR family transcriptional regulator 4926130 4189677 ECP_4776 Escherichia coli 536 MerR family transcriptional regulator YP_672559.1 4925846 D 362663 CDS YP_672560.1 110644830 4189678 complement(4926186..4927853) 1 NC_008253.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 4927853 4189678 ECP_4777 Escherichia coli 536 ABC transporter ATP-binding protein YP_672560.1 4926186 R 362663 CDS YP_672561.1 110644831 4190634 4928060..4929997 1 NC_008253.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4929997 4190634 ECP_4778 Escherichia coli 536 lytic murein transglycosylase YP_672561.1 4928060 D 362663 CDS YP_672562.1 110644832 4190635 4930087..4930413 1 NC_008253.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4930413 4190635 ECP_4779 Escherichia coli 536 Trp operon repressor YP_672562.1 4930087 D 362663 CDS YP_672563.1 110644833 4190636 complement(4930486..4931022) 1 NC_008253.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4931022 4190636 ECP_4780 Escherichia coli 536 NTPase YP_672563.1 4930486 R 362663 CDS YP_672564.1 110644834 4190637 4931065..4931712 1 NC_008253.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4931712 4190637 ECP_4781 Escherichia coli 536 phosphoglycerate mutase YP_672564.1 4931065 D 362663 CDS YP_672565.1 110644835 4190638 complement(4931709..4932578) 1 NC_008253.1 right origin-binding protein 4932578 4190638 ECP_4782 Escherichia coli 536 right origin-binding protein YP_672565.1 4931709 R 362663 CDS YP_672566.1 110644836 4190639 4932789..4933262 1 NC_008253.1 hypothetical protein 4933262 4190639 ECP_4783 Escherichia coli 536 hypothetical protein YP_672566.1 4932789 D 362663 CDS YP_672567.1 110644837 4190640 4933275..4933964 1 NC_008253.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4933964 4190640 ECP_4784 Escherichia coli 536 DNA-binding response regulator CreB YP_672567.1 4933275 D 362663 CDS YP_672568.1 110644838 4190641 4933964..4935388 1 NC_008253.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4935388 4190641 ECP_4785 Escherichia coli 536 sensory histidine kinase CreC YP_672568.1 4933964 D 362663 CDS YP_672569.1 110644839 4190642 4935446..4936798 1 NC_008253.1 hypothetical protein 4936798 4190642 ECP_4786 Escherichia coli 536 hypothetical protein YP_672569.1 4935446 D 362663 CDS YP_672570.1 110644840 4190643 complement(4936858..4937574) 1 NC_008253.1 dye resistance protein; two-component response regulator 4937574 4190643 ECP_4787 Escherichia coli 536 two-component response regulator YP_672570.1 4936858 R 362663 CDS