-- dump date 20140619_081726 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_751957.1 26245918 1040154 190..255 1 NC_004431.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 255 thrL 1040154 thrL Escherichia coli CFT073 thr operon leader peptide NP_751957.1 190 D 199310 CDS NP_751958.1 26245919 1035914 534..911 1 NC_004431.1 Residues 2 to 125 of 125 are 94.35 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 911 1035914 c0002 Escherichia coli CFT073 hypothetical protein NP_751958.1 534 D 199310 CDS NP_751959.2 229106389 1038322 1048..3510 1 NC_004431.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 3510 thrA 1038322 thrA Escherichia coli CFT073 bifunctional aspartokinase I/homoserine dehydrogenase I NP_751959.2 1048 D 199310 CDS NP_751960.1 26245921 1038469 3512..4444 1 NC_004431.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 4444 thrB 1038469 thrB Escherichia coli CFT073 homoserine kinase NP_751960.1 3512 D 199310 CDS NP_751961.1 26245922 1036001 4445..5731 1 NC_004431.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 5731 thrC 1036001 thrC Escherichia coli CFT073 threonine synthase NP_751961.1 4445 D 199310 CDS NP_751962.1 26245923 1037959 5799..5948 1 NC_004431.1 hypothetical protein 5948 1037959 c0006 Escherichia coli CFT073 hypothetical protein NP_751962.1 5799 D 199310 CDS NP_751963.1 26245924 1038052 5945..6241 1 NC_004431.1 Escherichia coli K-12 ortholog: b0005; Escherichia coli O157:H7 ortholog: z0005; hypothetical protein 6241 yaaX 1038052 yaaX Escherichia coli CFT073 hypothetical protein NP_751963.1 5945 D 199310 CDS NP_751964.1 26245925 1038110 complement(6021..6269) 1 NC_004431.1 hypothetical protein 6269 1038110 c0008 Escherichia coli CFT073 hypothetical protein NP_751964.1 6021 R 199310 CDS NP_751965.1 26245926 1035917 6060..6323 1 NC_004431.1 hypothetical protein 6323 1035917 c0009 Escherichia coli CFT073 hypothetical protein NP_751965.1 6060 D 199310 CDS NP_751966.1 26245927 1037723 complement(6301..7077) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0006; Escherichia coli O157:H7 ortholog: z0006; hypothetical protein 7077 yaaA 1037723 yaaA Escherichia coli CFT073 hypothetical protein NP_751966.1 6301 R 199310 CDS NP_751967.1 26245928 1037720 complement(7147..8577) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0007; Escherichia coli O157:H7 ortholog: z0007; transporter yaaJ 8577 yaaJ 1037720 yaaJ Escherichia coli CFT073 transporter yaaJ NP_751967.1 7147 R 199310 CDS NP_751968.2 161486342 1036025 8856..9809 1 NC_004431.1 Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 9809 talB 1036025 talB Escherichia coli CFT073 transaldolase B NP_751968.2 8856 D 199310 CDS NP_751969.1 26245930 1035942 9921..10511 1 NC_004431.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 10511 mogA 1035942 mogA Escherichia coli CFT073 molybdenum cofactor biosynthesis protein MogA NP_751969.1 9921 D 199310 CDS YP_004853794.1 347357905 1040509 complement(10535..10672) 1 NC_004431.1 hypothetical protein 10672 1040509 c0014 Escherichia coli CFT073 hypothetical protein YP_004853794.1 10535 R 199310 CDS NP_751971.1 26245932 1035962 complement(10716..11282) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0010; Escherichia coli O157:H7 ortholog: z0010; hypothetical protein 11282 yaaH 1035962 yaaH Escherichia coli CFT073 hypothetical protein NP_751971.1 10716 R 199310 CDS NP_751972.1 26245933 1037634 complement(11431..12144) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0011; Escherichia coli O157:H7 ortholog: z0011; hypothetical protein 12144 yaaW 1037634 yaaW Escherichia coli CFT073 hypothetical protein NP_751972.1 11431 R 199310 CDS NP_751973.1 26245934 1037616 complement(12170..12574) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0013; Escherichia coli O157:H7 ortholog: z0013; hypothetical protein 12574 yaaI 1037616 yaaI Escherichia coli CFT073 hypothetical protein NP_751973.1 12170 R 199310 CDS NP_751974.1 26245935 1037615 complement(12904..14940) 1 NC_004431.1 Residues 35 to 675 of 678 are 31.91 pct identical to residues 331 to 954 of 959 from GenPept.129 : >gb|AAG23119.1| (AF069527) glutamate dehydrogenase [Haloferax mediterranei]; glutamate dehydrogenase 14940 1037615 c0018 Escherichia coli CFT073 glutamate dehydrogenase NP_751974.1 12904 R 199310 CDS NP_751975.1 26245936 1036508 12946..14862 1 NC_004431.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14862 dnaK 1036508 dnaK Escherichia coli CFT073 molecular chaperone DnaK NP_751975.1 12946 D 199310 CDS NP_751976.1 26245937 1037422 14951..16081 1 NC_004431.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 16081 dnaJ 1037422 dnaJ Escherichia coli CFT073 molecular chaperone DnaJ NP_751976.1 14951 D 199310 CDS NP_751977.1 26245938 1036465 16953..17714 1 NC_004431.1 Residues 5 to 253 of 253 are 30.79 pct identical to residues 2 to 254 of 254 from MG1655 : b2408; hypothetical protein 17714 1036465 c0021 Escherichia coli CFT073 hypothetical protein NP_751977.1 16953 D 199310 CDS NP_751978.1 26245939 1037626 17698..19227 1 NC_004431.1 Residues 13 to 509 of 509 are 87.92 pct identical to residues 1 to 497 of 497 from GenPept.129 : >gb|AAL18999.1| (AE008695) arylsulfatase [Salmonella typhimurium LT2]; hypothetical protein 19227 1037626 c0022 Escherichia coli CFT073 hypothetical protein NP_751978.1 17698 D 199310 CDS NP_751979.1 26245940 1037604 19356..20615 1 NC_004431.1 Residues 1 to 411 of 419 are 67.15 pct identical to residues 3 to 413 of 417 from GenPept.129 : >gb|AAL19001.1| (AE008695) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 20615 1037604 c0023 Escherichia coli CFT073 hypothetical protein NP_751979.1 19356 D 199310 CDS NP_751980.1 26245941 1037840 20850..22016 1 NC_004431.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 22016 nhaA 1037840 nhaA Escherichia coli CFT073 pH-dependent sodium/proton antiporter NP_751980.1 20850 D 199310 CDS NP_751981.2 161486341 1035929 22082..22981 1 NC_004431.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22981 nhaR 1035929 nhaR Escherichia coli CFT073 transcriptional activator NhaR NP_751981.2 22082 D 199310 CDS NP_751982.1 26245943 1038106 complement(22948..23076) 1 NC_004431.1 hypothetical protein 23076 1038106 c0026 Escherichia coli CFT073 hypothetical protein NP_751982.1 22948 R 199310 CDS NP_751983.1 26245944 1035920 complement(23077..23340) 1 NC_004431.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 23340 rpsT 1035920 rpsT Escherichia coli CFT073 30S ribosomal protein S20 NP_751983.1 23077 R 199310 CDS NP_751984.1 26245945 1038116 23443..23661 1 NC_004431.1 Escherichia coli K-12 ortholog: b0024; Escherichia coli O157:H7 ortholog: z0028; hypothetical protein 23661 yaaY 1038116 yaaY Escherichia coli CFT073 hypothetical protein NP_751984.1 23443 D 199310 CDS NP_751985.1 26245946 1035912 23669..24610 1 NC_004431.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 24610 ribF 1035912 ribF Escherichia coli CFT073 bifunctional riboflavin kinase/FMN adenylyltransferase NP_751985.1 23669 D 199310 CDS NP_751986.1 26245947 1038281 24653..27469 1 NC_004431.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 27469 ileS 1038281 ileS Escherichia coli CFT073 isoleucyl-tRNA synthetase NP_751986.1 24653 D 199310 CDS NP_751987.1 26245948 1036002 27469..27963 1 NC_004431.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 27963 lspA 1036002 lspA Escherichia coli CFT073 lipoprotein signal peptidase NP_751987.1 27469 D 199310 CDS NP_751988.1 26245949 1036009 28071..28520 1 NC_004431.1 Escherichia coli K-12 ortholog: b0028; Escherichia coli O157:H7 ortholog: z0033; FKBP-type peptidylprolyl isomerase 28520 slpA 1036009 slpA Escherichia coli CFT073 FKBP-type peptidylprolyl isomerase NP_751988.1 28071 D 199310 CDS NP_751989.2 161486340 1038695 28522..29472 1 NC_004431.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 29472 ispH 1038695 ispH Escherichia coli CFT073 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_751989.2 28522 D 199310 CDS NP_751990.1 26245951 1036209 30475..30840 1 NC_004431.1 Residues 6 to 117 of 121 are 38.05 pct identical to residues 7 to 107 of 116 from GenPept.129 : >gb|AAF96824.1| (AE004420) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 30840 1036209 c0036 Escherichia coli CFT073 hypothetical protein NP_751990.1 30475 D 199310 CDS NP_751991.1 26245952 1036149 31001..31822 1 NC_004431.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31822 dapB 1036149 dapB Escherichia coli CFT073 dihydrodipicolinate reductase NP_751991.1 31001 D 199310 CDS NP_751992.1 26245953 1036154 complement(31864..32031) 1 NC_004431.1 hypothetical protein 32031 1036154 c0038 Escherichia coli CFT073 hypothetical protein NP_751992.1 31864 R 199310 CDS NP_751993.1 26245954 1040037 32101..32238 1 NC_004431.1 hypothetical protein 32238 1040037 c0039 Escherichia coli CFT073 hypothetical protein NP_751993.1 32101 D 199310 CDS NP_751994.1 26245955 1038618 32251..33426 1 NC_004431.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 33426 carA 1038618 carA Escherichia coli CFT073 carbamoyl phosphate synthase small subunit NP_751994.1 32251 D 199310 CDS NP_751995.1 26245956 1038143 33444..36665 1 NC_004431.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 36665 carB 1038143 carB Escherichia coli CFT073 carbamoyl phosphate synthase large subunit NP_751995.1 33444 D 199310 CDS NP_751996.1 26245957 1035994 complement(36673..36891) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0039; hypothetical protein 36891 1035994 c0042 Escherichia coli CFT073 hypothetical protein NP_751996.1 36673 R 199310 CDS NP_751997.2 161486339 1039091 36926..37321 1 NC_004431.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 37321 caiF 1039091 caiF Escherichia coli CFT073 DNA-binding transcriptional activator CaiF NP_751997.2 36926 D 199310 CDS NP_751998.1 26245959 1038841 complement(37440..38051) 1 NC_004431.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 38051 caiE 1038841 caiE Escherichia coli CFT073 carnitine operon protein CaiE NP_751998.1 37440 R 199310 CDS NP_751999.2 229106388 1035947 complement(38036..38821) 1 NC_004431.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 38821 caiD 1035947 caiD Escherichia coli CFT073 carnitinyl-CoA dehydratase NP_751999.2 38036 R 199310 CDS NP_752000.1 26245961 1036117 complement(38930..40498) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0037; Escherichia coli O157:H7 ortholog: z0043; crotonobetaine/carnitine-CoA ligase 40498 caiC 1036117 caiC Escherichia coli CFT073 crotonobetaine/carnitine-CoA ligase NP_752000.1 38930 R 199310 CDS NP_752001.1 26245962 1039569 complement(40556..41773) 1 NC_004431.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 41773 caiB 1039569 caiB Escherichia coli CFT073 crotonobetainyl-CoA:carnitine CoA-transferase NP_752001.1 40556 R 199310 CDS NP_752002.1 26245963 1035910 complement(41901..43043) 1 NC_004431.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 43043 caiA 1035910 caiA Escherichia coli CFT073 crotonobetainyl-CoA dehydrogenase NP_752002.1 41901 R 199310 CDS NP_752003.1 26245964 1036049 complement(43074..44588) 1 NC_004431.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 44588 caiT 1036049 caiT Escherichia coli CFT073 L-carnitine/gamma-butyrobetaine antiporter NP_752003.1 43074 R 199310 CDS NP_752004.2 161486338 1036200 45061..45831 1 NC_004431.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45831 fixA 1036200 fixA Escherichia coli CFT073 electron transfer flavoprotein FixA NP_752004.2 45061 D 199310 CDS NP_752005.1 26245966 1039636 46809..48095 1 NC_004431.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 48095 fixC 1039636 fixC Escherichia coli CFT073 oxidoreductase FixC NP_752005.1 46809 D 199310 CDS NP_752006.1 26245967 1035905 48092..48379 1 NC_004431.1 Escherichia coli K-12 ortholog: b0044; Escherichia coli O157:H7 ortholog: z0050; ferredoxin-like protein 48379 fixX 1035905 fixX Escherichia coli CFT073 ferredoxin-like protein NP_752006.1 48092 D 199310 CDS NP_752007.1 26245968 1039632 48438..49769 1 NC_004431.1 Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051; metabolite transporter 49769 yaaU 1039632 yaaU Escherichia coli CFT073 metabolite transporter NP_752007.1 48438 D 199310 CDS NP_752008.1 26245969 1040497 49877..50407 1 NC_004431.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 50407 yabF 1040497 yabF Escherichia coli CFT073 glutathione-regulated potassium-efflux system ancillary protein KefF NP_752008.1 49877 D 199310 CDS NP_752009.1 26245970 1035128 50400..52262 1 NC_004431.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 52262 kefC 1035128 kefC Escherichia coli CFT073 glutathione-regulated potassium-efflux system protein KefC NP_752009.1 50400 D 199310 CDS NP_752010.1 26245971 1035973 52319..52933 1 NC_004431.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52933 folA 1035973 folA Escherichia coli CFT073 dihydrofolate reductase NP_752010.1 52319 D 199310 CDS NP_752011.1 26245972 1037711 53019..53252 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0056; antitoxin of gyrase inhibiting toxin-antitoxin system 53252 1037711 c0059 Escherichia coli CFT073 antitoxin of gyrase inhibiting toxin-antitoxin system NP_752011.1 53019 D 199310 CDS NP_752012.1 26245973 1034976 53255..53569 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0057; toxin of gyrase inhibiting toxin-antitoxin system 53569 1034976 c0060 Escherichia coli CFT073 toxin of gyrase inhibiting toxin-antitoxin system NP_752012.1 53255 D 199310 CDS NP_752013.1 26245974 1038673 complement(53566..54414) 1 NC_004431.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 54414 apaH 1038673 apaH Escherichia coli CFT073 diadenosine tetraphosphatase NP_752013.1 53566 R 199310 CDS NP_752014.1 26245975 1034956 54385..54738 1 NC_004431.1 hypothetical protein 54738 1034956 c0062 Escherichia coli CFT073 hypothetical protein NP_752014.1 54385 D 199310 CDS NP_752015.1 26245976 1036565 complement(54421..54798) 1 NC_004431.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 54798 apaG 1036565 apaG Escherichia coli CFT073 ApaG protein NP_752015.1 54421 R 199310 CDS NP_752016.1 26245977 1035880 complement(54801..55622) 1 NC_004431.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 55622 ksgA 1035880 ksgA Escherichia coli CFT073 dimethyladenosine transferase NP_752016.1 54801 R 199310 CDS NP_752017.1 26245978 1035368 complement(55619..56608) 1 NC_004431.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 56608 pdxA 1035368 pdxA Escherichia coli CFT073 4-hydroxythreonine-4-phosphate dehydrogenase NP_752017.1 55619 R 199310 CDS NP_752018.1 26245979 1035369 complement(56608..57894) 1 NC_004431.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 57894 surA 1035369 surA Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase SurA NP_752018.1 56608 R 199310 CDS NP_752019.1 26245980 1037628 complement(57947..60301) 1 NC_004431.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 60301 imp 1037628 imp Escherichia coli CFT073 organic solvent tolerance protein NP_752019.1 57947 R 199310 CDS NP_752020.2 161486337 1035622 60556..61371 1 NC_004431.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 61371 djlA 1035622 djlA Escherichia coli CFT073 Dna-J like membrane chaperone protein NP_752020.2 60556 D 199310 CDS NP_752021.1 26245982 1040435 complement(61489..62148) 1 NC_004431.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 62148 yabO 1040435 yabO Escherichia coli CFT073 23S rRNA/tRNA pseudouridine synthase A NP_752021.1 61489 R 199310 CDS NP_752022.1 26245983 1035881 complement(62160..65066) 1 NC_004431.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 65066 hepA 1035881 hepA Escherichia coli CFT073 ATP-dependent helicase HepA NP_752022.1 62160 R 199310 CDS NP_752023.1 26245984 1038159 complement(65231..67582) 1 NC_004431.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 67582 polB 1038159 polB Escherichia coli CFT073 DNA polymerase II NP_752023.1 65231 R 199310 CDS NP_752024.1 26245985 1038698 67723..68232 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 68232 1038698 c0072 Escherichia coli CFT073 transposase NP_752024.1 67723 D 199310 CDS NP_752025.1 26245986 1035252 complement(68369..69064) 1 NC_004431.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 69064 araD 1035252 araD Escherichia coli CFT073 L-ribulose-5-phosphate 4-epimerase NP_752025.1 68369 R 199310 CDS NP_752026.1 26245987 1038173 complement(69349..70851) 1 NC_004431.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 70851 araA 1038173 araA Escherichia coli CFT073 L-arabinose isomerase NP_752026.1 69349 R 199310 CDS NP_752027.1 26245988 1040445 complement(70862..72562) 1 NC_004431.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 72562 araB 1040445 araB Escherichia coli CFT073 ribulokinase NP_752027.1 70862 R 199310 CDS NP_752028.1 26245989 1034955 72901..73746 1 NC_004431.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 73746 araC 1034955 araC Escherichia coli CFT073 DNA-binding transcriptional regulator AraC NP_752028.1 72901 D 199310 CDS NP_752029.1 26245990 1035883 74011..74133 1 NC_004431.1 Residues 5 to 40 of 40 are 66.66 pct identical to residues 308 to 343 of 343 from GenPept.129 : >gb|AAL72384.1| (AF386526) hypothetical protein [Shigella flexneri 2a]; hypothetical protein 74133 1035883 c0077 Escherichia coli CFT073 hypothetical protein NP_752029.1 74011 D 199310 CDS NP_752030.1 26245991 1035206 74258..74494 1 NC_004431.1 Residues 2 to 76 of 78 are 38.46 pct identical to residues 1 to 72 of 231 from GenPept.129 : >emb|CAC92308.1| (AJ414155) hypothetical protein [Yersinia pestis]; hypothetical protein 74494 1035206 c0078 Escherichia coli CFT073 hypothetical protein NP_752030.1 74258 D 199310 CDS NP_752031.1 26245992 1035949 74536..75108 1 NC_004431.1 Residues 14 to 125 of 190 are 44.64 pct identical to residues 54 to 164 of 189 from GenPept.129 : >emb|CAC90441.1| (AJ414149) hypothetical protein [Yersinia pestis]; hypothetical protein 75108 1035949 c0079 Escherichia coli CFT073 hypothetical protein NP_752031.1 74536 D 199310 CDS NP_752032.1 26245993 1036542 75115..75537 1 NC_004431.1 hypothetical protein 75537 1036542 c0080 Escherichia coli CFT073 hypothetical protein NP_752032.1 75115 D 199310 CDS NP_752033.1 26245994 1038727 75692..76456 1 NC_004431.1 Escherichia coli K-12 ortholog: b0065; Escherichia coli O157:H7 ortholog: z0074; hypothetical protein 76456 yabI 1038727 yabI Escherichia coli CFT073 hypothetical protein NP_752033.1 75692 D 199310 CDS NP_752034.2 229106387 1036401 complement(76570..77268) 1 NC_004431.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 77268 thiQ 1036401 thiQ Escherichia coli CFT073 thiamine transporter ATP-binding subunit NP_752034.2 76570 R 199310 CDS NP_752035.1 26245996 1035173 complement(77252..78862) 1 NC_004431.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 78862 thiP 1035173 thiP Escherichia coli CFT073 thiamine transporter membrane protein NP_752035.1 77252 R 199310 CDS NP_752036.2 161486336 1038158 complement(78838..79821) 1 NC_004431.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 79821 tbpA 1038158 tbpA Escherichia coli CFT073 thiamine transporter substrate binding subunit NP_752036.2 78838 R 199310 CDS NP_752037.1 26245998 1038194 complement(79985..81661) 1 NC_004431.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 81661 yabN 1038194 yabN Escherichia coli CFT073 transcriptional regulator SgrR NP_752037.1 79985 R 199310 CDS NP_752038.1 26245999 1038203 82026..82535 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 82535 1038203 c0086 Escherichia coli CFT073 transposase NP_752038.1 82026 D 199310 CDS NP_752039.1 26246000 1038100 complement(82679..83284) 1 NC_004431.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 83284 leuD 1038100 leuD Escherichia coli CFT073 isopropylmalate isomerase small subunit NP_752039.1 82679 R 199310 CDS NP_752040.1 26246001 1036072 82730..82915 1 NC_004431.1 hypothetical protein 82915 1036072 c0088 Escherichia coli CFT073 hypothetical protein NP_752040.1 82730 D 199310 CDS NP_752041.1 26246002 1036454 complement(83295..84695) 1 NC_004431.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 84695 leuC 1036454 leuC Escherichia coli CFT073 isopropylmalate isomerase large subunit NP_752041.1 83295 R 199310 CDS NP_752042.2 161486335 1036210 complement(84698..85789) 1 NC_004431.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 85789 leuB 1036210 leuB Escherichia coli CFT073 3-isopropylmalate dehydrogenase NP_752042.2 84698 R 199310 CDS NP_752043.1 26246004 1038600 complement(85789..87402) 1 NC_004431.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 87402 leuA 1038600 leuA Escherichia coli CFT073 2-isopropylmalate synthase NP_752043.1 85789 R 199310 CDS NP_752044.1 26246005 1036568 complement(87451..87537) 1 NC_004431.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 87537 leuL 1036568 leuL Escherichia coli CFT073 leu operon leader peptide NP_752044.1 87451 R 199310 CDS NP_752045.1 26246006 1038206 87996..88118 1 NC_004431.1 hypothetical protein 88118 1038206 c0092 Escherichia coli CFT073 hypothetical protein NP_752045.1 87996 D 199310 CDS NP_752046.2 161486334 1036529 88177..89139 1 NC_004431.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 89139 leuO 1036529 leuO Escherichia coli CFT073 leucine transcriptional activator NP_752046.2 88177 D 199310 CDS NP_752047.1 26246008 1038214 complement(89175..89303) 1 NC_004431.1 hypothetical protein 89303 1038214 c0094 Escherichia coli CFT073 hypothetical protein NP_752047.1 89175 R 199310 CDS NP_752048.2 161486333 1038215 89457..91181 1 NC_004431.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 91181 ilvI 1038215 ilvI Escherichia coli CFT073 acetolactate synthase 3 catalytic subunit NP_752048.2 89457 D 199310 CDS NP_752049.2 161486332 1035721 91184..91675 1 NC_004431.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 91675 ilvH 1035721 ilvH Escherichia coli CFT073 acetolactate synthase 3 regulatory subunit NP_752049.2 91184 D 199310 CDS YP_004853795.1 347357922 1038230 91687..91773 1 NC_004431.1 hypothetical protein 91773 1038230 c5493 Escherichia coli CFT073 hypothetical protein YP_004853795.1 91687 D 199310 CDS NP_752051.1 26246012 1038226 91727..91858 1 NC_004431.1 hypothetical protein 91858 1038226 c0097 Escherichia coli CFT073 hypothetical protein NP_752051.1 91727 D 199310 CDS NP_752052.1 26246013 1035886 91855..92859 1 NC_004431.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 92859 fruR 1035886 fruR Escherichia coli CFT073 DNA-binding transcriptional regulator FruR NP_752052.1 91855 D 199310 CDS NP_752053.1 26246014 1035671 93425..93919 1 NC_004431.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 93919 yabB 1035671 yabB Escherichia coli CFT073 cell division protein MraZ NP_752053.1 93425 D 199310 CDS NP_752054.1 26246015 1038217 93921..94862 1 NC_004431.1 Escherichia coli K-12 ortholog: b0082; Escherichia coli O157:H7 ortholog: z0092; S-adenosyl-methyltransferase MraW 94862 mraW 1038217 mraW Escherichia coli CFT073 S-adenosyl-methyltransferase MraW NP_752054.1 93921 D 199310 CDS NP_752055.1 26246016 1038220 94859..95224 1 NC_004431.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 95224 ftsL 1038220 ftsL Escherichia coli CFT073 cell division protein FtsL NP_752055.1 94859 D 199310 CDS NP_752056.1 26246017 1040459 95240..97006 1 NC_004431.1 Penicillin-binding protein 3; Escherichia coli K-12 ortholog: b0084; Escherichia coli O157:H7 ortholog: z0094; peptidoglycan synthetase ftsI 97006 ftsI 1040459 ftsI Escherichia coli CFT073 peptidoglycan synthetase ftsI NP_752056.1 95240 D 199310 CDS NP_752057.1 26246018 1035233 96993..98480 1 NC_004431.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 98480 murE 1035233 murE Escherichia coli CFT073 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase NP_752057.1 96993 D 199310 CDS NP_752058.1 26246019 1035941 98477..99835 1 NC_004431.1 Escherichia coli K-12 ortholog: b0086; Escherichia coli O157:H7 ortholog: z0096; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 99835 murF 1035941 murF Escherichia coli CFT073 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase NP_752058.1 98477 D 199310 CDS NP_752059.1 26246020 1035664 99829..100911 1 NC_004431.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 100911 mraY 1035664 mraY Escherichia coli CFT073 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_752059.1 99829 D 199310 CDS NP_752060.1 26246021 1038341 100914..102230 1 NC_004431.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 102230 murD 1038341 murD Escherichia coli CFT073 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_752060.1 100914 D 199310 CDS NP_752061.1 26246022 1035981 102227..103474 1 NC_004431.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 103474 ftsW 1035981 ftsW Escherichia coli CFT073 cell division protein FtsW NP_752061.1 102227 D 199310 CDS NP_752062.1 26246023 1036005 103471..104538 1 NC_004431.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 104538 murG 1036005 murG Escherichia coli CFT073 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_752062.1 103471 D 199310 CDS NP_752063.1 26246024 1038105 104592..106067 1 NC_004431.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 106067 murC 1038105 murC Escherichia coli CFT073 UDP-N-acetylmuramate--L-alanine ligase NP_752063.1 104592 D 199310 CDS NP_752064.1 26246025 1038266 106060..106980 1 NC_004431.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 106980 ddl 1038266 ddl Escherichia coli CFT073 D-alanine--D-alanine ligase NP_752064.1 106060 D 199310 CDS NP_752065.1 26246026 1035662 106982..107812 1 NC_004431.1 involved in septum formation; cell division protein FtsQ 107812 ftsQ 1035662 ftsQ Escherichia coli CFT073 cell division protein FtsQ NP_752065.1 106982 D 199310 CDS NP_752066.1 26246027 1038103 107809..109071 1 NC_004431.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 109071 ftsA 1038103 ftsA Escherichia coli CFT073 cell division protein FtsA NP_752066.1 107809 D 199310 CDS NP_752067.1 26246028 1035944 109132..110283 1 NC_004431.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 110283 ftsZ 1035944 ftsZ Escherichia coli CFT073 cell division protein FtsZ NP_752067.1 109132 D 199310 CDS NP_752068.1 26246029 1037189 110384..111301 1 NC_004431.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 111301 lpxC 1037189 lpxC Escherichia coli CFT073 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_752068.1 110384 D 199310 CDS NP_752069.2 161486331 1037447 111532..112044 1 NC_004431.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112044 yacA 1037447 yacA Escherichia coli CFT073 SecA regulator SecM NP_752069.2 111532 D 199310 CDS NP_752070.1 26246031 1035616 112106..114811 1 NC_004431.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 114811 secA 1035616 secA Escherichia coli CFT073 preprotein translocase subunit SecA NP_752070.1 112106 D 199310 CDS NP_752071.1 26246032 1038581 114871..115269 1 NC_004431.1 7,8-dihydro-8-oxoguanine-triphosphatase; Escherichia coli K-12 ortholog: b0099; Escherichia coli O157:H7 ortholog: z0109; nucleoside triphosphate pyrophosphohydrolase 115269 mutT 1038581 mutT Escherichia coli CFT073 nucleoside triphosphate pyrophosphohydrolase NP_752071.1 114871 D 199310 CDS NP_752072.1 26246033 1035330 115372..115893 1 NC_004431.1 Residues 1 to 173 of 173 are 99.42 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|Q47309|YI9A_ECOLI INSERTION ELEMENT IS1397 HYPOTHETICAL 20.1 KD PROTEIN (ORFA); hypothetical protein 115893 1035330 c0118 Escherichia coli CFT073 hypothetical protein NP_752072.1 115372 D 199310 CDS NP_752073.1 26246034 1038102 115993..116715 1 NC_004431.1 Escherichia coli K-12 ortholog: b3558; transposase insK 116715 1038102 c0119 Escherichia coli CFT073 transposase insK NP_752073.1 115993 D 199310 CDS NP_752074.1 26246035 1035000 116785..116982 1 NC_004431.1 hypothetical protein 116982 1035000 c0120 Escherichia coli CFT073 hypothetical protein NP_752074.1 116785 D 199310 CDS NP_752075.1 26246036 1035890 complement(116788..116985) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0101; Escherichia coli O157:H7 ortholog: z0111; zinc-binding protein 116985 yacG 1035890 yacG Escherichia coli CFT073 zinc-binding protein NP_752075.1 116788 R 199310 CDS NP_752076.1 26246037 1035891 complement(116995..117738) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0102; Escherichia coli O157:H7 ortholog: z0112; hypothetical protein 117738 yacF 1035891 yacF Escherichia coli CFT073 hypothetical protein NP_752076.1 116995 R 199310 CDS NP_752077.1 26246038 1039004 complement(117738..118358) 1 NC_004431.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 118358 coaE 1039004 coaE Escherichia coli CFT073 dephospho-CoA kinase NP_752077.1 117738 R 199310 CDS NP_752078.1 26246039 1037488 118583..119626 1 NC_004431.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 119626 guaC 1037488 guaC Escherichia coli CFT073 guanosine 5'-monophosphate oxidoreductase NP_752078.1 118583 D 199310 CDS NP_752079.1 26246040 1035893 complement(119661..120863) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0106; Escherichia coli O157:H7 ortholog: z0116; type IV pilin biogenesis protein 120863 hofC 1035893 hofC Escherichia coli CFT073 type IV pilin biogenesis protein NP_752079.1 119661 R 199310 CDS NP_752080.1 26246041 1038132 complement(120853..122238) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0107; Escherichia coli O157:H7 ortholog: z0117; hypothetical protein 122238 hofB 1038132 hofB Escherichia coli CFT073 hypothetical protein NP_752080.1 120853 R 199310 CDS NP_752081.1 26246042 1038736 complement(122248..122688) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0108; Escherichia coli O157:H7 ortholog: z0118; major pilin subunit 122688 ppdD 1038736 ppdD Escherichia coli CFT073 major pilin subunit NP_752081.1 122248 R 199310 CDS NP_752082.2 161486330 1036374 complement(122892..123785) 1 NC_004431.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 123785 nadC 1036374 nadC Escherichia coli CFT073 quinolinate phosphoribosyltransferase NP_752082.2 122892 R 199310 CDS NP_752083.1 26246044 1036599 123873..124424 1 NC_004431.1 Escherichia coli K-12 ortholog: b0110; Escherichia coli O157:H7 ortholog: z0120; N-acetyl-anhydromuranmyl-L-alanine amidase 124424 ampD 1036599 ampD Escherichia coli CFT073 N-acetyl-anhydromuranmyl-L-alanine amidase NP_752083.1 123873 D 199310 CDS NP_752084.1 26246045 1036494 124421..125275 1 NC_004431.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 125275 ampE 1036494 ampE Escherichia coli CFT073 regulatory protein AmpE NP_752084.1 124421 D 199310 CDS NP_752085.1 26246046 1036490 complement(125318..126688) 1 NC_004431.1 General aromatic amino acid permease; Escherichia coli K-12 ortholog: b0112; Escherichia coli O157:H7 ortholog: z0122; aromatic amino acid transporter 126688 aroP 1036490 aroP Escherichia coli CFT073 aromatic amino acid transporter NP_752085.1 125318 R 199310 CDS NP_752086.1 26246047 1036502 128997..129293 1 NC_004431.1 Residues 5 to 95 of 98 are 45.16 pct identical to residues 2 to 85 of 87 from SwissProt.40 : >sp|Q03708|IMM7_ECOLI COLICIN E7 IMMUNITY PROTEIN (IMME7) (MICROCIN E7 IMMUNITY PROTEIN); hypothetical protein 129293 1036502 c0133 Escherichia coli CFT073 hypothetical protein NP_752086.1 128997 D 199310 CDS NP_752087.1 26246048 1036484 complement(129267..129410) 1 NC_004431.1 hypothetical protein 129410 1036484 c0134 Escherichia coli CFT073 hypothetical protein NP_752087.1 129267 R 199310 CDS NP_752088.1 26246049 1036341 complement(129968..130090) 1 NC_004431.1 hypothetical protein 130090 1036341 c0136 Escherichia coli CFT073 hypothetical protein NP_752088.1 129968 R 199310 CDS NP_752089.1 26246050 1036552 130380..130670 1 NC_004431.1 Residues 5 to 93 of 96 are 46.06 pct identical to residues 4 to 85 of 87 from SwissProt.40 : >sp|Q03708|IMM7_ECOLI COLICIN E7 IMMUNITY PROTEIN (IMME7) (MICROCIN E7 IMMUNITY PROTEIN); hypothetical protein 130670 1036552 c0137 Escherichia coli CFT073 hypothetical protein NP_752089.1 130380 D 199310 CDS NP_752090.1 26246051 1036081 131044..131370 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 131370 1036081 c0138 Escherichia coli CFT073 hypothetical protein NP_752090.1 131044 D 199310 CDS NP_752091.1 26246052 1035861 131367..132257 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 132257 1035861 c0139 Escherichia coli CFT073 transposase IS629 NP_752091.1 131367 D 199310 CDS NP_752092.2 161486329 1036476 132439..133203 1 NC_004431.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 133203 pdhR 1036476 pdhR Escherichia coli CFT073 transcriptional regulator PdhR NP_752092.2 132439 D 199310 CDS NP_752093.1 26246054 1035906 complement(133200..133382) 1 NC_004431.1 hypothetical protein 133382 1035906 c0141 Escherichia coli CFT073 hypothetical protein NP_752093.1 133200 R 199310 CDS NP_752094.1 26246055 1040471 133364..136027 1 NC_004431.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 136027 aceE 1040471 aceE Escherichia coli CFT073 pyruvate dehydrogenase subunit E1 NP_752094.1 133364 D 199310 CDS NP_752095.2 161486328 1037753 138143..139567 1 NC_004431.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 139567 lpdA 1037753 lpdA Escherichia coli CFT073 dihydrolipoamide dehydrogenase NP_752095.2 138143 D 199310 CDS NP_752096.1 26246057 1040499 complement(139809..141590) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0117; Escherichia coli O157:H7 ortholog: z0127; hypothetical protein 141590 yacH 1040499 yacH Escherichia coli CFT073 hypothetical protein NP_752096.1 139809 R 199310 CDS NP_752097.2 161486327 1036517 141945..144542 1 NC_004431.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 144542 acnB 1036517 acnB Escherichia coli CFT073 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase NP_752097.2 141945 D 199310 CDS NP_752098.2 161486326 1035678 144717..145079 1 NC_004431.1 Escherichia coli K-12 ortholog: b0119; Escherichia coli O157:H7 ortholog: z0129; hypothetical protein 145079 yacL 1035678 yacL Escherichia coli CFT073 hypothetical protein NP_752098.2 144717 D 199310 CDS NP_752099.1 26246060 1037308 complement(145117..145911) 1 NC_004431.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 145911 speD 1037308 speD Escherichia coli CFT073 S-adenosylmethionine decarboxylase NP_752099.1 145117 R 199310 CDS NP_752100.1 26246061 1040054 complement(145927..146793) 1 NC_004431.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 146793 speE 1040054 speE Escherichia coli CFT073 spermidine synthase NP_752100.1 145927 R 199310 CDS NP_752101.1 26246062 1039884 complement(146899..147417) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0122; Escherichia coli O157:H7 ortholog: z0132; hypothetical protein 147417 yacC 1039884 yacC Escherichia coli CFT073 hypothetical protein NP_752101.1 146899 R 199310 CDS NP_752102.2 161486325 1040023 147412..148962 1 NC_004431.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 148962 yacK 1040023 yacK Escherichia coli CFT073 multicopper oxidase NP_752102.2 147412 D 199310 CDS NP_752103.1 26246064 1037173 complement(149040..151448) 1 NC_004431.1 Pyrroloquinoline-quinone; Escherichia coli K-12 ortholog: b0124; Escherichia coli O157:H7 ortholog: z0134; glucose dehydrogenase 151448 gcd 1037173 gcd Escherichia coli CFT073 glucose dehydrogenase NP_752103.1 149040 R 199310 CDS NP_752104.2 161486324 1040065 151636..152172 1 NC_004431.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 152172 hpt 1040065 hpt Escherichia coli CFT073 hypoxanthine-guanine phosphoribosyltransferase NP_752104.2 151636 D 199310 CDS NP_752105.1 26246066 1037331 complement(152213..152875) 1 NC_004431.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 152875 yadF 1037331 yadF Escherichia coli CFT073 carbonic anhydrase NP_752105.1 152213 R 199310 CDS NP_752106.1 26246067 1035410 152984..153910 1 NC_004431.1 Escherichia coli K-12 ortholog: b0127; Escherichia coli O157:H7 ortholog: z0138; ABC transporter ATP-binding protein 153910 yadG 1035410 yadG Escherichia coli CFT073 ABC transporter ATP-binding protein NP_752106.1 152984 D 199310 CDS NP_752107.1 26246068 1035963 153907..154677 1 NC_004431.1 Escherichia coli K-12 ortholog: b0128; Escherichia coli O157:H7 ortholog: z0139; hypothetical protein 154677 yadH 1035963 yadH Escherichia coli CFT073 hypothetical protein NP_752107.1 153907 D 199310 CDS NP_752108.1 26246069 1038099 154782..155222 1 NC_004431.1 Escherichia coli K-12 ortholog: b0129; Escherichia coli O157:H7 ortholog: z0140; PTS system IIA component yadI 155222 yadI 1038099 yadI Escherichia coli CFT073 PTS system IIA component yadI NP_752108.1 154782 D 199310 CDS NP_752109.1 26246070 1036680 155286..156515 1 NC_004431.1 Escherichia coli K-12 ortholog: b0130; Escherichia coli O157:H7 ortholog: z0141; hypothetical protein 156515 yadE 1036680 yadE Escherichia coli CFT073 hypothetical protein NP_752109.1 155286 D 199310 CDS NP_752110.1 26246071 1037618 complement(156519..156899) 1 NC_004431.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 156899 panD 1037618 panD Escherichia coli CFT073 aspartate alpha-decarboxylase NP_752110.1 156519 R 199310 CDS NP_752111.1 26246072 1040423 156867..157052 1 NC_004431.1 hypothetical protein 157052 1040423 c0161 Escherichia coli CFT073 hypothetical protein NP_752111.1 156867 D 199310 CDS NP_752112.1 26246073 1035964 157173..158117 1 NC_004431.1 Escherichia coli K-12 ortholog: b0132; Escherichia coli O157:H7 ortholog: z0143; hypothetical protein 158117 yadD 1035964 yadD Escherichia coli CFT073 hypothetical protein NP_752112.1 157173 D 199310 CDS NP_752113.1 26246074 1039167 158186..158383 1 NC_004431.1 Residues 4 to 63 of 65 are 68.75 pct identical to residues 235 to 298 of 298 from GenPept.129 : >gb|AAG54436.1|AE005189_9 (AE005189) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 158383 1039167 c0163 Escherichia coli CFT073 hypothetical protein NP_752113.1 158186 D 199310 CDS NP_752114.1 26246075 1039422 complement(158465..159238) 1 NC_004431.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 159238 panC 1039422 panC Escherichia coli CFT073 pantoate--beta-alanine ligase NP_752114.1 158465 R 199310 CDS NP_752115.1 26246076 1036661 complement(159329..160123) 1 NC_004431.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 160123 panB 1036661 panB Escherichia coli CFT073 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_752115.1 159329 R 199310 CDS NP_752116.1 26246077 1036698 complement(160235..161524) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0135; fimbrial-like adhesin protein 161524 yadC 1036698 yadC Escherichia coli CFT073 fimbrial-like adhesin protein NP_752116.1 160235 R 199310 CDS NP_752117.1 26246078 1039659 complement(161550..162146) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0136; hypothetical protein 162146 yadK 1039659 yadK Escherichia coli CFT073 hypothetical protein NP_752117.1 161550 R 199310 CDS NP_752118.1 26246079 1039625 complement(162173..162787) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0137; Escherichia coli O157:H7 ortholog: z0148; hypothetical protein 162787 yadL 1039625 yadL Escherichia coli CFT073 hypothetical protein NP_752118.1 162173 R 199310 CDS NP_752119.1 26246080 1039623 complement(162793..163359) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0138; Escherichia coli O157:H7 ortholog: z0149; hypothetical protein 163359 yadM 1039623 yadM Escherichia coli CFT073 hypothetical protein NP_752119.1 162793 R 199310 CDS NP_752120.1 26246081 1039139 complement(163376..165964) 1 NC_004431.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 165964 htrE 1039139 htrE Escherichia coli CFT073 outer membrane usher protein NP_752120.1 163376 R 199310 CDS NP_752121.1 26246082 1037625 complement(165999..166739) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0140; Escherichia coli O157:H7 ortholog: z0151; chaperone protein EcpD 166739 ecpD 1037625 ecpD Escherichia coli CFT073 chaperone protein EcpD NP_752121.1 165999 R 199310 CDS NP_752122.1 26246083 1038086 complement(166848..167462) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0141; Escherichia coli O157:H7 ortholog: z0152; fimbrial-like protein yadN 167462 yadN 1038086 yadN Escherichia coli CFT073 fimbrial-like protein yadN NP_752122.1 166848 R 199310 CDS NP_752123.1 26246084 1035277 complement(167431..167571) 1 NC_004431.1 hypothetical protein 167571 1035277 c0173 Escherichia coli CFT073 hypothetical protein NP_752123.1 167431 R 199310 CDS NP_752124.1 26246085 1040426 167479..167607 1 NC_004431.1 hypothetical protein 167607 1040426 c0174 Escherichia coli CFT073 hypothetical protein NP_752124.1 167479 D 199310 CDS NP_752125.1 26246086 1039898 complement(167802..168281) 1 NC_004431.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 168281 folK 1039898 folK Escherichia coli CFT073 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_752125.1 167802 R 199310 CDS NP_752126.1 26246087 1037253 complement(168278..169696) 1 NC_004431.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 169696 pcnB 1037253 pcnB Escherichia coli CFT073 poly(A) polymerase NP_752126.1 168278 R 199310 CDS NP_752127.2 161486323 1038583 complement(169735..170631) 1 NC_004431.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 170631 yadB 1038583 yadB Escherichia coli CFT073 glutamyl-Q tRNA(Asp) synthetase NP_752127.2 169735 R 199310 CDS NP_752128.2 161486322 1038134 complement(170698..171153) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0145; Escherichia coli O157:H7 ortholog: z0156; RNA polymerase-binding transcription factor 171153 dksA 1038134 dksA Escherichia coli CFT073 RNA polymerase-binding transcription factor NP_752128.2 170698 R 199310 CDS NP_752129.1 26246090 1039832 complement(171331..172035) 1 NC_004431.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 172035 sfsA 1039832 sfsA Escherichia coli CFT073 sugar fermentation stimulation protein A NP_752129.1 171331 R 199310 CDS NP_752130.1 26246091 1039113 complement(172050..172589) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0147; Escherichia coli O157:H7 ortholog: z0158; 2'-5' RNA ligase 172589 yadP 1039113 yadP Escherichia coli CFT073 2'-5' RNA ligase NP_752130.1 172050 R 199310 CDS NP_752131.1 26246092 1037155 172609..175083 1 NC_004431.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 175083 hrpB 1037155 hrpB Escherichia coli CFT073 ATP-dependent RNA helicase HrpB NP_752131.1 172609 D 199310 CDS NP_752132.1 26246093 1040478 complement(175011..175178) 1 NC_004431.1 hypothetical protein 175178 1040478 c0182 Escherichia coli CFT073 hypothetical protein NP_752132.1 175011 R 199310 CDS NP_752133.1 26246094 1040454 175177..177711 1 NC_004431.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 177711 mrcB 1040454 mrcB Escherichia coli CFT073 penicillin-binding protein 1b NP_752133.1 175177 D 199310 CDS NP_752134.1 26246095 1040468 complement(177776..177958) 1 NC_004431.1 hypothetical protein 177958 1040468 c0184 Escherichia coli CFT073 hypothetical protein NP_752134.1 177776 R 199310 CDS NP_752135.1 26246096 1035322 177931..180189 1 NC_004431.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 180189 fhuA 1035322 fhuA Escherichia coli CFT073 ferrichrome outer membrane transporter NP_752135.1 177931 D 199310 CDS NP_752136.2 161486321 1038423 180240..181037 1 NC_004431.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 181037 fhuC 1038423 fhuC Escherichia coli CFT073 iron-hydroxamate transporter ATP-binding subunit NP_752136.2 180240 D 199310 CDS NP_752137.1 26246098 1035877 181034..181927 1 NC_004431.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 181927 fhuD 1035877 fhuD Escherichia coli CFT073 iron-hydroxamate transporter substrate-binding subunit NP_752137.1 181034 D 199310 CDS NP_752138.1 26246099 1038971 181924..183906 1 NC_004431.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 183906 fhuB 1038971 fhuB Escherichia coli CFT073 iron-hydroxamate transporter permease subunit NP_752138.1 181924 D 199310 CDS NP_752139.1 26246100 1035152 complement(183941..185221) 1 NC_004431.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 185221 hemL 1035152 hemL Escherichia coli CFT073 glutamate-1-semialdehyde aminotransferase NP_752139.1 183941 R 199310 CDS NP_752140.1 26246101 1037702 185446..186867 1 NC_004431.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 186867 yadQ 1037702 yadQ Escherichia coli CFT073 chloride channel protein NP_752140.1 185446 D 199310 CDS NP_752141.1 26246102 1035141 186916..187293 1 NC_004431.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 187293 yadR 1035141 yadR Escherichia coli CFT073 iron-sulfur cluster insertion protein ErpA NP_752141.1 186916 D 199310 CDS NP_752142.1 26246103 1035863 complement(187045..187305) 1 NC_004431.1 hypothetical protein 187305 1035863 c0192 Escherichia coli CFT073 hypothetical protein NP_752142.1 187045 R 199310 CDS NP_752143.1 26246104 1035163 complement(187340..187963) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0157; Escherichia coli O157:H7 ortholog: z0168; hypothetical protein 187963 yadS 1035163 yadS Escherichia coli CFT073 hypothetical protein NP_752143.1 187340 R 199310 CDS NP_752144.1 26246105 1038962 complement(188001..188801) 1 NC_004431.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 188801 yadT 1038962 yadT Escherichia coli CFT073 vitamin B12-transporter protein BtuF NP_752144.1 188001 R 199310 CDS NP_752145.1 26246106 1035162 complement(188794..189492) 1 NC_004431.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 189492 pfs 1035162 pfs Escherichia coli CFT073 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_752145.1 188794 R 199310 CDS NP_752146.1 26246107 1038164 189576..191093 1 NC_004431.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 191093 dgt 1038164 dgt Escherichia coli CFT073 deoxyguanosinetriphosphate triphosphohydrolase NP_752146.1 189576 D 199310 CDS NP_752147.1 26246108 1035843 191223..192647 1 NC_004431.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 192647 htrA 1035843 htrA Escherichia coli CFT073 serine endoprotease NP_752147.1 191223 D 199310 CDS NP_752148.1 26246109 1035272 192782..193291 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 193291 1035272 c0198 Escherichia coli CFT073 transposase NP_752148.1 192782 D 199310 CDS NP_752149.2 161486320 1035191 193513..194670 1 NC_004431.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 194670 yaeG 1035191 yaeG Escherichia coli CFT073 carbohydrate diacid transcriptional activator CdaR NP_752149.2 193513 D 199310 CDS NP_752150.1 26246111 1039053 complement(194723..195109) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0163; Escherichia coli O157:H7 ortholog: z0175; hypothetical protein 195109 yaeH 1039053 yaeH Escherichia coli CFT073 hypothetical protein NP_752150.1 194723 R 199310 CDS NP_752151.1 26246112 1037369 complement(195421..196245) 1 NC_004431.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 196245 dapD 1037369 dapD Escherichia coli CFT073 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_752151.1 195421 R 199310 CDS NP_752152.1 26246113 1035903 complement(196276..198948) 1 NC_004431.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 198948 glnD 1035903 glnD Escherichia coli CFT073 PII uridylyl-transferase NP_752152.1 196276 R 199310 CDS NP_752153.1 26246114 1035347 complement(199010..199804) 1 NC_004431.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 199804 map 1035347 map Escherichia coli CFT073 methionine aminopeptidase NP_752153.1 199010 R 199310 CDS NP_752154.2 161486319 1036400 200172..200897 1 NC_004431.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 200897 rpsB 1036400 rpsB Escherichia coli CFT073 30S ribosomal protein S2 NP_752154.2 200172 D 199310 CDS NP_752155.1 26246116 1037643 complement(200849..201778) 1 NC_004431.1 hypothetical protein 201778 1037643 c0205 Escherichia coli CFT073 hypothetical protein NP_752155.1 200849 R 199310 CDS NP_752156.1 26246117 1039042 201032..201883 1 NC_004431.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 201883 tsf 1039042 tsf Escherichia coli CFT073 elongation factor Ts NP_752156.1 201032 D 199310 CDS NP_752157.1 26246118 1040461 202030..202755 1 NC_004431.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 202755 pyrH 1040461 pyrH Escherichia coli CFT073 uridylate kinase NP_752157.1 202030 D 199310 CDS NP_752158.1 26246119 1035876 202905..203462 1 NC_004431.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 203462 frr 1035876 frr Escherichia coli CFT073 ribosome recycling factor NP_752158.1 202905 D 199310 CDS NP_752159.1 26246120 1035882 204938..205699 1 NC_004431.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 205699 yaeS 1035882 yaeS Escherichia coli CFT073 undecaprenyl pyrophosphate synthase NP_752159.1 204938 D 199310 CDS NP_752160.1 26246121 1035795 205712..206569 1 NC_004431.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 206569 cdsA 1035795 cdsA Escherichia coli CFT073 CDP-diglyceride synthase NP_752160.1 205712 D 199310 CDS NP_752161.1 26246122 1035797 206536..207933 1 NC_004431.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 207933 yaeL 1035797 yaeL Escherichia coli CFT073 zinc metallopeptidase RseP NP_752161.1 206536 D 199310 CDS NP_752162.1 26246123 1038708 207963..210395 1 NC_004431.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 210395 yaeT 1038708 yaeT Escherichia coli CFT073 outer membrane protein assembly factor YaeT NP_752162.1 207963 D 199310 CDS NP_752163.1 26246124 1035875 210517..211002 1 NC_004431.1 DNA-binding 17 kDa protein; Escherichia coli K-12 ortholog: b0178; Escherichia coli O157:H7 ortholog: z0190; periplasmic chaperone 211002 hlpA 1035875 hlpA Escherichia coli CFT073 periplasmic chaperone NP_752163.1 210517 D 199310 CDS NP_752164.1 26246125 1035816 211006..212031 1 NC_004431.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 212031 lpxD 1035816 lpxD Escherichia coli CFT073 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_752164.1 211006 D 199310 CDS NP_752165.1 26246126 1037553 212043..212591 1 NC_004431.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 212591 fabZ 1037553 fabZ Escherichia coli CFT073 (3R)-hydroxymyristoyl-ACP dehydratase NP_752165.1 212043 D 199310 CDS NP_752166.1 26246127 1039054 212595..213383 1 NC_004431.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 213383 lpxA 1039054 lpxA Escherichia coli CFT073 UDP-N-acetylglucosamine acyltransferase NP_752166.1 212595 D 199310 CDS NP_752167.1 26246128 1035825 213383..214531 1 NC_004431.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 214531 lpxB 1035825 lpxB Escherichia coli CFT073 lipid-A-disaccharide synthase NP_752167.1 213383 D 199310 CDS NP_752168.1 26246129 1035867 214528..215124 1 NC_004431.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 215124 rnhB 1035867 rnhB Escherichia coli CFT073 ribonuclease HII NP_752168.1 214528 D 199310 CDS NP_752169.1 26246130 1038041 215161..218643 1 NC_004431.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 218643 dnaE 1038041 dnaE Escherichia coli CFT073 DNA polymerase III subunit alpha NP_752169.1 215161 D 199310 CDS NP_752170.1 26246131 1035778 complement(218587..219522) 1 NC_004431.1 hypothetical protein 219522 1035778 c0222 Escherichia coli CFT073 hypothetical protein NP_752170.1 218587 R 199310 CDS NP_752171.1 26246132 1035804 218656..219615 1 NC_004431.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 219615 accA 1035804 accA Escherichia coli CFT073 acetyl-CoA carboxylase carboxyltransferase subunit alpha NP_752171.1 218656 D 199310 CDS NP_752172.1 26246133 1039108 219713..221854 1 NC_004431.1 Escherichia coli K-12 ortholog: b0186; Escherichia coli O157:H7 ortholog: z0198; lysine decarboxylase, constitutive 221854 ldcC 1039108 ldcC Escherichia coli CFT073 lysine decarboxylase, constitutive NP_752172.1 219713 D 199310 CDS NP_752173.2 161486318 1035895 221911..222300 1 NC_004431.1 Escherichia coli K-12 ortholog: b0187; Escherichia coli O157:H7 ortholog: z0199; hypothetical protein 222300 yaeR 1035895 yaeR Escherichia coli CFT073 hypothetical protein NP_752173.2 221911 D 199310 CDS NP_752174.1 26246135 1035896 222365..223678 1 NC_004431.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 223678 tilS 1035896 tilS Escherichia coli CFT073 tRNA(Ile)-lysidine synthetase NP_752174.1 222365 D 199310 CDS NP_752175.1 26246136 1040430 complement(223712..223972) 1 NC_004431.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 223972 yaeO 1040430 yaeO Escherichia coli CFT073 Rho-binding antiterminator NP_752175.1 223712 R 199310 CDS NP_752176.1 26246137 1036145 complement(223959..224159) 1 NC_004431.1 Residues 1 to 66 of 66 are 98.48 pct identical to residues 1 to 66 of 66 from SwissProt.40 : >sp|P52099|YAEP_ECOLI Hypothetical protein yaeP; hypothetical protein 224159 1036145 c0228 Escherichia coli CFT073 hypothetical protein NP_752176.1 223959 R 199310 CDS NP_752177.1 26246138 1035958 224325..224870 1 NC_004431.1 Escherichia coli K-12 ortholog: b0190; Escherichia coli O157:H7 ortholog: z0202; hypothetical protein 224870 yaeQ 1035958 yaeQ Escherichia coli CFT073 hypothetical protein NP_752177.1 224325 D 199310 CDS NP_752178.1 26246139 1039631 224867..225289 1 NC_004431.1 Escherichia coli K-12 ortholog: b0191; Escherichia coli O157:H7 ortholog: z0203; peptidyl-tRNA hydrolase domain protein 225289 yaeJ 1039631 yaeJ Escherichia coli CFT073 peptidyl-tRNA hydrolase domain protein NP_752178.1 224867 D 199310 CDS NP_752179.1 26246140 1035184 225303..226013 1 NC_004431.1 Lipoprotein nlpE; Escherichia coli K-12 ortholog: b0192; Escherichia coli O157:H7 ortholog: z0204; lipoprotein involved with copper homeostasis and adhesion 226013 cutF 1035184 cutF Escherichia coli CFT073 lipoprotein involved with copper homeostasis and adhesion NP_752179.1 225303 D 199310 CDS NP_752180.1 26246141 1037489 complement(226161..226883) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3558; transposase insK 226883 1037489 c0232 Escherichia coli CFT073 transposase insK NP_752180.1 226161 R 199310 CDS NP_752181.1 26246142 1036589 complement(226983..227513) 1 NC_004431.1 Residues 4 to 176 of 176 are 99.42 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|Q47309|YI9A_ECOLI INSERTION ELEMENT IS1397 HYPOTHETICAL 20.1 KD PROTEIN (ORFA); hypothetical protein 227513 1036589 c0233 Escherichia coli CFT073 hypothetical protein NP_752181.1 226983 R 199310 CDS NP_752182.2 161486317 1038507 complement(227599..228423) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0193; Escherichia coli O157:H7 ortholog: z0205; hypothetical protein 228423 yaeF 1038507 yaeF Escherichia coli CFT073 hypothetical protein NP_752182.2 227599 R 199310 CDS NP_752183.2 161486316 1037637 complement(228476..230194) 1 NC_004431.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 230194 proS 1037637 proS Escherichia coli CFT073 prolyl-tRNA synthetase NP_752183.2 228476 R 199310 CDS NP_752184.1 26246145 1036674 complement(230305..231012) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0195; Escherichia coli O157:H7 ortholog: z0207; hypothetical protein 231012 yaeB 1036674 yaeB Escherichia coli CFT073 hypothetical protein NP_752184.1 230305 R 199310 CDS NP_752185.1 26246146 1040431 complement(231009..231413) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0196; Escherichia coli O157:H7 ortholog: z0208; outer membrane lipoprotein 231413 rcsF 1040431 rcsF Escherichia coli CFT073 outer membrane lipoprotein NP_752185.1 231009 R 199310 CDS NP_752186.1 26246147 1035167 complement(231531..232343) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0197; Escherichia coli O157:H7 ortholog: z0209; DL-methionine transporter substrate-binding subunit 232343 metQ 1035167 metQ Escherichia coli CFT073 DL-methionine transporter substrate-binding subunit NP_752186.1 231531 R 199310 CDS NP_752187.1 26246148 1039647 complement(232383..233036) 1 NC_004431.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit 233036 yaeE 1039647 yaeE Escherichia coli CFT073 DL-methionine transporter permease subunit NP_752187.1 232383 R 199310 CDS NP_752188.1 26246149 1039648 complement(233029..234060) 1 NC_004431.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 234060 metN 1039648 metN Escherichia coli CFT073 DL-methionine transporter ATP-binding subunit NP_752188.1 233029 R 199310 CDS NP_752189.1 26246150 1040234 234248..234820 1 NC_004431.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 234820 yaeD 1040234 yaeD Escherichia coli CFT073 D,D-heptose 1,7-bisphosphate phosphatase NP_752189.1 234248 D 199310 CDS NP_752190.1 26246151 1035470 240568..241371 1 NC_004431.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 241371 dkgB 1035470 dkgB Escherichia coli CFT073 2,5-diketo-D-gluconate reductase B NP_752190.1 240568 D 199310 CDS NP_752191.1 26246152 1035687 complement(241368..242282) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0208; Escherichia coli O157:H7 ortholog: z0230; transcriptional regulator YafC 242282 yafC 1035687 yafC Escherichia coli CFT073 transcriptional regulator YafC NP_752191.1 241368 R 199310 CDS NP_752192.1 26246153 1036014 242499..243323 1 NC_004431.1 Escherichia coli K-12 ortholog: b0209; Escherichia coli O157:H7 ortholog: z0232; hypothetical protein 243323 yafD 1036014 yafD Escherichia coli CFT073 hypothetical protein NP_752192.1 242499 D 199310 CDS NP_752193.1 26246154 1035838 243401..244171 1 NC_004431.1 Escherichia coli K-12 ortholog: b0210; Escherichia coli O157:H7 ortholog: z0233; hypothetical protein 244171 yafE 1035838 yafE Escherichia coli CFT073 hypothetical protein NP_752193.1 243401 D 199310 CDS NP_752194.1 26246155 1036039 complement(244220..245578) 1 NC_004431.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 245578 mltD 1036039 mltD Escherichia coli CFT073 membrane-bound lytic murein transglycosylase D NP_752194.1 244220 R 199310 CDS NP_752195.1 26246156 1040410 complement(245650..246405) 1 NC_004431.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 246405 gloB 1040410 gloB Escherichia coli CFT073 hydroxyacylglutathione hydrolase NP_752195.1 245650 R 199310 CDS NP_752196.1 26246157 1039521 246421..247161 1 NC_004431.1 Escherichia coli K-12 ortholog: b0213; Escherichia coli O157:H7 ortholog: z0237; hypothetical protein 247161 yafS 1039521 yafS Escherichia coli CFT073 hypothetical protein NP_752196.1 246421 D 199310 CDS NP_752197.2 161486315 1036861 complement(247158..247625) 1 NC_004431.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 247625 rnhA 1036861 rnhA Escherichia coli CFT073 ribonuclease H NP_752197.2 247158 R 199310 CDS NP_752198.1 26246159 1035245 247681..248421 1 NC_004431.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 248421 dnaQ 1035245 dnaQ Escherichia coli CFT073 DNA polymerase III subunit epsilon NP_752198.1 247681 D 199310 CDS NP_752199.1 26246160 1038034 248670..249014 1 NC_004431.1 hypothetical protein 249014 1038034 c0253 Escherichia coli CFT073 hypothetical protein NP_752199.1 248670 D 199310 CDS NP_752200.1 26246161 1036564 complement(248751..248996) 1 NC_004431.1 Residues 1 to 75 of 81 are 53.33 pct identical to residues 205 to 279 of 280 from GenPept.129 : >gb|AAL57572.1|AF453442_1 (AF453442) unknown [Escherichia coli]; hypothetical protein 248996 1036564 c0254 Escherichia coli CFT073 hypothetical protein NP_752200.1 248751 R 199310 CDS NP_752201.1 26246162 1040495 complement(249162..249608) 1 NC_004431.1 Residues 1 to 148 of 148 are 70.94 pct identical to residues 1 to 148 of 174 from GenPept.129 : >gb|AAL67385.1|AF447814_53 (AF447814) L0010-like protein [Escherichia coli]; hypothetical protein 249608 1040495 c0255 Escherichia coli CFT073 hypothetical protein NP_752201.1 249162 R 199310 CDS NP_752202.1 26246163 1039592 249923..250144 1 NC_004431.1 Residues 7 to 69 of 73 are 66.66 pct identical to residues 5 to 67 of 141 from GenPept.129 : >gb|AAG55763.1|AE005312_9 (AE005312) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 250144 1039592 c0256 Escherichia coli CFT073 hypothetical protein NP_752202.1 249923 D 199310 CDS NP_752203.1 26246164 1036555 250214..250564 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1599; hypothetical protein 250564 1036555 c0257 Escherichia coli CFT073 hypothetical protein NP_752203.1 250214 D 199310 CDS NP_752204.1 26246165 1036558 250595..251242 1 NC_004431.1 Residues 1 to 215 of 215 are 100.00 pct identical to residues 10 to 224 of 224 from GenPept.129 : >gb|AAL67334.1|AF447814_2 (AF447814) L0015-like protein [Escherichia coli]; hypothetical protein 251242 1036558 c0258 Escherichia coli CFT073 hypothetical protein NP_752204.1 250595 D 199310 CDS NP_752205.1 26246166 1036557 251193..252143 1 NC_004431.1 Residues 42 to 316 of 316 are 100.00 pct identical to residues 1 to 275 of 275 from GenPept.129 : >gb|AAL67335.1|AF447814_3 (AF447814) L0015-like protein [Escherichia coli]; hypothetical protein 252143 1036557 c0259 Escherichia coli CFT073 hypothetical protein NP_752205.1 251193 D 199310 CDS NP_752206.1 26246167 1036549 complement(251502..251666) 1 NC_004431.1 hypothetical protein 251666 1036549 c0260 Escherichia coli CFT073 hypothetical protein NP_752206.1 251502 R 199310 CDS NP_752207.1 26246168 1036553 complement(252253..253386) 1 NC_004431.1 Residues 8 to 372 of 377 are 47.26 pct identical to residues 39 to 390 of 390 from SwissProt.40 : >sp|P55626|Y4QE_RHISN TRANSPOSASE Y4QE; hypothetical protein 253386 1036553 c0261 Escherichia coli CFT073 hypothetical protein NP_752207.1 252253 R 199310 CDS NP_752208.1 26246169 1036551 253450..253635 1 NC_004431.1 Residues 1 to 61 of 61 are 100.00 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 253635 1036551 c0262 Escherichia coli CFT073 hypothetical protein NP_752208.1 253450 D 199310 CDS NP_752209.1 26246170 1036546 253783..254469 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4330; transposase 254469 1036546 c0263 Escherichia coli CFT073 transposase NP_752209.1 253783 D 199310 CDS NP_752210.1 26246171 1036545 254517..254771 1 NC_004431.1 Residues 1 to 84 of 84 are 97.61 pct identical to residues 260 to 343 of 343 from GenPept.129 : >emb|CAA29389.1| (X05955) ORF (343 AA) [Shigella sonnei]; hypothetical protein 254771 1036545 c0264 Escherichia coli CFT073 hypothetical protein NP_752210.1 254517 D 199310 CDS NP_752211.1 26246172 1036541 complement(254850..255197) 1 NC_004431.1 Residues 1 to 115 of 115 are 100.00 pct identical to residues 1 to 115 of 115 from GenPept.129 : >gb|AAL67339.1|AF447814_7 (AF447814) L0008-like protein [Escherichia coli]; hypothetical protein 255197 1036541 c0265 Escherichia coli CFT073 hypothetical protein NP_752211.1 254850 R 199310 CDS NP_752212.1 26246173 1036538 256927..257682 1 NC_004431.1 Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 257682 1036538 c0268 Escherichia coli CFT073 hypothetical protein NP_752212.1 256927 D 199310 CDS NP_752213.1 26246174 1036534 complement(257757..258134) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 258134 1036534 c0269 Escherichia coli CFT073 hypothetical protein NP_752213.1 257757 R 199310 CDS NP_752214.1 26246175 1036531 complement(258181..258645) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z1658; hypothetical protein 258645 1036531 c0270 Escherichia coli CFT073 hypothetical protein NP_752214.1 258181 R 199310 CDS NP_752215.1 26246176 1036533 complement(258605..259249) 1 NC_004431.1 Residues 178 to 214 of 214 are 72.97 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein 259249 1036533 c0271 Escherichia coli CFT073 hypothetical protein NP_752215.1 258605 R 199310 CDS NP_752216.1 26246177 1036528 complement(259268..259489) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 259489 1036528 c0272 Escherichia coli CFT073 hypothetical protein NP_752216.1 259268 R 199310 CDS NP_752217.1 26246178 1036498 complement(259552..260043) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 260043 1036498 c0273 Escherichia coli CFT073 radC-like protein yeeS NP_752217.1 259552 R 199310 CDS NP_752218.1 26246179 1036520 259564..260523 1 NC_004431.1 Residues 1 to 319 of 319 are 100.00 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 260523 1036520 c0274 Escherichia coli CFT073 hypothetical protein NP_752218.1 259564 D 199310 CDS NP_752219.1 26246180 1036519 complement(260044..260589) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 260589 1036519 c0275 Escherichia coli CFT073 hypothetical protein NP_752219.1 260044 R 199310 CDS NP_752220.1 26246181 1036513 complement(260611..260835) 1 NC_004431.1 Residues 1 to 45 of 74 are 97.77 pct identical to residues 8 to 52 of 271 from GenPept.129 : >gb|AAK00478.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 260835 1036513 c0276 Escherichia coli CFT073 hypothetical protein NP_752220.1 260611 R 199310 CDS NP_752221.1 26246182 1036518 260823..261671 1 NC_004431.1 Residues 90 to 282 of 282 are 100.00 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAL67348.1|AF447814_16 (AF447814) unknown [Escherichia coli]; hypothetical protein 261671 1036518 c0277 Escherichia coli CFT073 hypothetical protein NP_752221.1 260823 D 199310 CDS NP_752222.1 26246183 1036516 complement(260856..261677) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 261677 1036516 c0278 Escherichia coli CFT073 hypothetical protein NP_752222.1 260856 R 199310 CDS NP_752223.1 26246184 1036505 complement(261777..262010) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0249; hypothetical protein 262010 1036505 c0279 Escherichia coli CFT073 hypothetical protein NP_752223.1 261777 R 199310 CDS NP_752224.1 26246185 1036514 complement(262128..262613) 1 NC_004431.1 Residues 12 to 161 of 161 are 100.00 pct identical to residues 1 to 150 of 150 from GenPept.129 : >gb|AAL67352.1|AF447814_20 (AF447814) unknown [Escherichia coli]; hypothetical protein 262613 1036514 c0280 Escherichia coli CFT073 hypothetical protein NP_752224.1 262128 R 199310 CDS NP_752225.1 26246186 1040256 complement(262736..262984) 1 NC_004431.1 Residues 1 to 82 of 82 are 100.00 pct identical to residues 1 to 82 of 82 from GenPept.129 : >gb|AAL67353.1|AF447814_21 (AF447814) unknown [Escherichia coli]; hypothetical protein 262984 1040256 c0281 Escherichia coli CFT073 hypothetical protein NP_752225.1 262736 R 199310 CDS NP_752226.1 26246187 1036506 complement(263015..263653) 1 NC_004431.1 Residues 4 to 212 of 212 are 100.00 pct identical to residues 1 to 209 of 209 from GenPept.129 : >gb|AAL67354.1|AF447814_22 (AF447814) unknown [Escherichia coli]; hypothetical protein 263653 1036506 c0282 Escherichia coli CFT073 hypothetical protein NP_752226.1 263015 R 199310 CDS NP_752227.1 26246188 1036503 complement(263700..264206) 1 NC_004431.1 Residues 1 to 168 of 168 are 100.00 pct identical to residues 1 to 168 of 168 from GenPept.129 : >gb|AAL67355.1|AF447814_23 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 264206 1036503 c0283 Escherichia coli CFT073 hypothetical protein NP_752227.1 263700 R 199310 CDS NP_752228.1 26246189 1036491 complement(264296..265366) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1654; hypothetical protein 265366 1036491 c0284 Escherichia coli CFT073 hypothetical protein NP_752228.1 264296 R 199310 CDS NP_752229.1 26246190 1040035 complement(265363..266268) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1653; hypothetical protein 266268 1040035 c0285 Escherichia coli CFT073 hypothetical protein NP_752229.1 265363 R 199310 CDS NP_752230.1 26246191 1036499 complement(266265..268076) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1652; hypothetical protein 268076 1036499 c0286 Escherichia coli CFT073 hypothetical protein NP_752230.1 266265 R 199310 CDS NP_752231.1 26246192 1036486 complement(268315..268662) 1 NC_004431.1 Residues 1 to 108 of 115 are 97.22 pct identical to residues 2 to 109 of 795 from GenPept.129 : >gb|AAG55767.1|AE005313_2 (AE005313) unknown [Escherichia coli O157:H7 EDL933]; hypothetical protein 268662 1036486 c0287 Escherichia coli CFT073 hypothetical protein NP_752231.1 268315 R 199310 CDS NP_752232.1 26246193 1039658 complement(268880..269005) 1 NC_004431.1 Residues 1 to 41 of 41 are 97.56 pct identical to residues 63 to 103 of 103 from GenPept.129 : >gb|AAL67360.1|AF447814_28 (AF447814) unknown [Escherichia coli]; hypothetical protein 269005 1039658 c0288 Escherichia coli CFT073 hypothetical protein NP_752232.1 268880 R 199310 CDS NP_752233.1 26246194 1036483 complement(269022..269378) 1 NC_004431.1 Residues 22 to 86 of 118 are 98.46 pct identical to residues 1 to 65 of 290 from GenPept.129 : >gb|AAL99256.1| (AY082443) unknown [Escherichia coli]; hypothetical protein 269378 1036483 c0289 Escherichia coli CFT073 hypothetical protein NP_752233.1 269022 R 199310 CDS NP_752234.1 26246195 1036470 complement(269537..270640) 1 NC_004431.1 Residues 32 to 289 of 367 are 93.82 pct identical to residues 5 to 263 of 268 from GenPept.129 : >gb|AAL67361.1|AF447814_29 (AF447814) unknown [Escherichia coli]; hypothetical protein 270640 1036470 c0290 Escherichia coli CFT073 hypothetical protein NP_752234.1 269537 R 199310 CDS NP_752235.1 26246196 1036481 271030..271638 1 NC_004431.1 Residues 3 to 202 of 202 are 100.00 pct identical to residues 1 to 200 of 200 from GenPept.129 : >gb|AAL67363.1|AF447814_31 (AF447814) recombinase [Escherichia coli]; hypothetical protein 271638 1036481 c0291 Escherichia coli CFT073 hypothetical protein NP_752235.1 271030 D 199310 CDS YP_004853796.1 347357923 1036468 271866..272603 1 NC_004431.1 hypothetical protein 272603 1036468 c0292 Escherichia coli CFT073 hypothetical protein YP_004853796.1 271866 D 199310 CDS NP_752237.1 26246198 1037725 complement(272721..273530) 1 NC_004431.1 Residues 1 to 269 of 269 are 100.00 pct identical to residues 1 to 269 of 269 from GenPept.129 : >gb|AAL67365.1|AF447814_33 (AF447814) unknown [Escherichia coli]; hypothetical protein 273530 1037725 c0293 Escherichia coli CFT073 hypothetical protein NP_752237.1 272721 R 199310 CDS NP_752238.1 26246199 1040052 274013..276178 1 NC_004431.1 Residues 1 to 530 of 721 are 100.00 pct identical to residues 1 to 530 of 536 from GenPept.129 : >gb|AAL67366.1|AF447814_34 (AF447814) truncated ferric siderophore receptor [Escherichia coli]; hypothetical protein 276178 1040052 c0294 Escherichia coli CFT073 hypothetical protein NP_752238.1 274013 D 199310 CDS NP_752239.1 26246200 1036464 276186..277178 1 NC_004431.1 Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]; hypothetical protein 277178 1036464 c0295 Escherichia coli CFT073 hypothetical protein NP_752239.1 276186 D 199310 CDS NP_752240.1 26246201 1036457 277197..278255 1 NC_004431.1 Residues 1 to 352 of 352 are 100.00 pct identical to residues 1 to 352 of 352 from GenPept.129 : >gb|AAL67369.1|AF447814_37 (AF447814) permease [Escherichia coli]; hypothetical protein 278255 1036457 c0296 Escherichia coli CFT073 hypothetical protein NP_752240.1 277197 D 199310 CDS NP_752241.1 26246202 1036460 278252..279019 1 NC_004431.1 Residues 1 to 255 of 255 are 100.00 pct identical to residues 1 to 255 of 255 from GenPept.129 : >gb|AAL67370.1|AF447814_38 (AF447814) ferric-enterobactin-transport protein [Escherichia coli]; hypothetical protein 279019 1036460 c0297 Escherichia coli CFT073 hypothetical protein NP_752241.1 278252 D 199310 CDS NP_752242.1 26246203 1036583 279868..280236 1 NC_004431.1 hypothetical protein 280236 1036583 c0298 Escherichia coli CFT073 hypothetical protein NP_752242.1 279868 D 199310 CDS NP_752243.1 26246204 1036456 279881..280306 1 NC_004431.1 hypothetical protein 280306 1036456 c0299 Escherichia coli CFT073 hypothetical protein NP_752243.1 279881 D 199310 CDS NP_752244.1 26246205 1036442 complement(279920..280066) 1 NC_004431.1 hypothetical protein 280066 1036442 c0300 Escherichia coli CFT073 hypothetical protein NP_752244.1 279920 R 199310 CDS NP_752245.1 26246206 1036452 280838..281023 1 NC_004431.1 hypothetical protein 281023 1036452 c0301 Escherichia coli CFT073 hypothetical protein NP_752245.1 280838 D 199310 CDS NP_752246.1 26246207 1036458 281124..281261 1 NC_004431.1 hypothetical protein 281261 1036458 c0302 Escherichia coli CFT073 hypothetical protein NP_752246.1 281124 D 199310 CDS NP_752247.1 26246208 1036436 complement(281170..281313) 1 NC_004431.1 hypothetical protein 281313 1036436 c0303 Escherichia coli CFT073 hypothetical protein NP_752247.1 281170 R 199310 CDS NP_752248.1 26246209 1036453 281760..281960 1 NC_004431.1 hypothetical protein 281960 1036453 c0304 Escherichia coli CFT073 hypothetical protein NP_752248.1 281760 D 199310 CDS NP_752249.1 26246210 1036445 complement(281863..282471) 1 NC_004431.1 Residues 1 to 202 of 202 are 92.07 pct identical to residues 1 to 202 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 282471 1036445 c0305 Escherichia coli CFT073 hypothetical protein NP_752249.1 281863 R 199310 CDS NP_752250.1 26246211 1036446 complement(282559..282765) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1627; hypothetical protein 282765 1036446 c0306 Escherichia coli CFT073 hypothetical protein NP_752250.1 282559 R 199310 CDS NP_752251.1 26246212 1036440 complement(283149..283940) 1 NC_004431.1 Residues 9 to 164 of 263 are 96.15 pct identical to residues 1 to 156 of 156 from GenPept.129 : >gb|AAK00470.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 283940 1036440 c0307 Escherichia coli CFT073 hypothetical protein NP_752251.1 283149 R 199310 CDS NP_752252.1 26246213 1035985 285015..285155 1 NC_004431.1 Escherichia coli K-12 ortholog: b0460; Escherichia coli O157:H7 ortholog: z0573; hemolysin expression modulating protein 285155 1035985 c0308 Escherichia coli CFT073 hemolysin expression modulating protein NP_752252.1 285015 D 199310 CDS NP_752253.1 26246214 1036435 285387..285986 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1567; hypothetical protein 285986 1036435 c0309 Escherichia coli CFT073 hypothetical protein NP_752253.1 285387 D 199310 CDS NP_752254.1 26246215 1036443 286352..286741 1 NC_004431.1 Residues 3 to 129 of 129 are 88.97 pct identical to residues 1 to 127 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 286741 1036443 c0310 Escherichia coli CFT073 hypothetical protein NP_752254.1 286352 D 199310 CDS NP_752255.1 26246216 1036439 286738..287163 1 NC_004431.1 Residues 15 to 119 of 141 are 36.36 pct identical to residues 44 to 153 of 173 from GenPept.129 : >gb|AAL08463.1|AF326777_38 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 287163 1036439 c0311 Escherichia coli CFT073 hypothetical protein NP_752255.1 286738 D 199310 CDS NP_752256.1 26246217 1036424 287365..287607 1 NC_004431.1 Residues 30 to 80 of 80 are 76.47 pct identical to residues 48 to 98 of 98 from GenPept.129 : >gb|AAL08431.1|AF326777_6 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 287607 1036424 c0312 Escherichia coli CFT073 hypothetical protein NP_752256.1 287365 D 199310 CDS NP_752257.1 26246218 1036433 287635..288201 1 NC_004431.1 hypothetical protein 288201 1036433 c0313 Escherichia coli CFT073 hypothetical protein NP_752257.1 287635 D 199310 CDS NP_752258.1 26246219 1036428 288254..288409 1 NC_004431.1 hypothetical protein 288409 1036428 c0314 Escherichia coli CFT073 hypothetical protein NP_752258.1 288254 D 199310 CDS NP_752259.1 26246220 1036420 288306..288521 1 NC_004431.1 Residues 8 to 71 of 71 are 93.75 pct identical to residues 1 to 64 of 64 from GenPept.129 : >dbj|BAB34790.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 288521 1036420 c0315 Escherichia coli CFT073 hypothetical protein NP_752259.1 288306 D 199310 CDS NP_752260.1 26246221 1036427 complement(288427..288717) 1 NC_004431.1 Residues 1 to 68 of 96 are 70.58 pct identical to residues 69 to 136 of 148 from GenPept.129 : >gb|AAL67420.1|AF447814_88 (AF447814) unknown [Escherichia coli]; hypothetical protein 288717 1036427 c0316 Escherichia coli CFT073 hypothetical protein NP_752260.1 288427 R 199310 CDS NP_752261.1 26246222 1036422 288649..288786 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1627; hypothetical protein 288786 1036422 c0317 Escherichia coli CFT073 hypothetical protein NP_752261.1 288649 D 199310 CDS NP_752262.1 26246223 1036430 complement(289106..289744) 1 NC_004431.1 Residues 1 to 210 of 212 are 65.87 pct identical to residues 1 to 211 of 212 from GenPept.129 : >gb|AAL20848.1| (AE008786) ribose 5-phosphate isomerase [Salmonella typhimurium LT2]; hypothetical protein 289744 1036430 c0318 Escherichia coli CFT073 hypothetical protein NP_752262.1 289106 R 199310 CDS NP_752263.1 26246224 1036419 289986..291158 1 NC_004431.1 Residues 1 to 386 of 390 are 65.02 pct identical to residues 1 to 386 of 388 from SwissProt.40 : >sp|Q59418|OGL_ERWCA OLIGOGALACTURONIDE LYASE; oligogalacturonide lyase 291158 1036419 c0319 Escherichia coli CFT073 oligogalacturonide lyase NP_752263.1 289986 D 199310 CDS NP_752264.1 26246225 1036426 complement(290959..291114) 1 NC_004431.1 hypothetical protein 291114 1036426 c0320 Escherichia coli CFT073 hypothetical protein NP_752264.1 290959 R 199310 CDS NP_752265.1 26246226 1040242 291188..291988 1 NC_004431.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 291988 1040242 c0321 Escherichia coli CFT073 gluconate 5-dehydrogenase NP_752265.1 291188 D 199310 CDS NP_752266.1 26246227 1036423 292732..294246 1 NC_004431.1 Residues 16 to 496 of 504 are 56.93 pct identical to residues 13 to 495 of 508 from GenPept.129 : >emb|CAC44457.1| (AJ305143) oligogalacturonide transporter [Pectobacterium chrysanthemi]; oligogalacturonide transporter 294246 1036423 c0322 Escherichia coli CFT073 oligogalacturonide transporter NP_752266.1 292732 D 199310 CDS NP_752267.1 26246228 1036416 294176..296482 1 NC_004431.1 Residues 21 to 729 of 768 are 40.62 pct identical to residues 8 to 686 of 732 from GenPept.129 : >gb|AAL51034.1|AF454849_1 (AF454849) pectate lyase [Klebsiella oxytoca]; exopolygalacturonate lyase 296482 1036416 c0323 Escherichia coli CFT073 exopolygalacturonate lyase NP_752267.1 294176 D 199310 CDS NP_752268.1 26246229 1036417 complement(295181..295303) 1 NC_004431.1 hypothetical protein 295303 1036417 c0324 Escherichia coli CFT073 hypothetical protein NP_752268.1 295181 R 199310 CDS NP_752269.1 26246230 1034963 296575..297555 1 NC_004431.1 hypothetical protein 297555 1034963 c0325 Escherichia coli CFT073 hypothetical protein NP_752269.1 296575 D 199310 CDS NP_752270.1 26246231 1036418 complement(297875..298303) 1 NC_004431.1 Residues 1 to 142 of 142 are 86.71 pct identical to residues 83 to 225 of 228 from GenPept.129 : >emb|CAC43418.1| (X16664) hypothetical protein [Escherichia coli]; hypothetical protein 298303 1036418 c0326 Escherichia coli CFT073 hypothetical protein NP_752270.1 297875 R 199310 CDS NP_752271.1 26246232 1036403 complement(298646..299116) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1633; hypothetical protein 299116 1036403 c0327 Escherichia coli CFT073 hypothetical protein NP_752271.1 298646 R 199310 CDS NP_752272.1 26246233 1036408 complement(299622..299861) 1 NC_004431.1 hypothetical protein 299861 1036408 c0328 Escherichia coli CFT073 hypothetical protein NP_752272.1 299622 R 199310 CDS NP_752273.1 26246234 1036406 299991..300116 1 NC_004431.1 hypothetical protein 300116 1036406 c0329 Escherichia coli CFT073 hypothetical protein NP_752273.1 299991 D 199310 CDS NP_752274.1 26246235 1036413 complement(300643..301428) 1 NC_004431.1 Residues 2 to 261 of 261 are 83.58 pct identical to residues 1 to 261 of 261 from GenPept.129 : >gb|AAL22652.1| (AE008876) regulatory protein, deoR family [Salmonella typhimurium LT2]; deoxyribose operon repressor 301428 1036413 c0330 Escherichia coli CFT073 deoxyribose operon repressor NP_752274.1 300643 R 199310 CDS NP_752275.1 26246236 1036407 301731..302651 1 NC_004431.1 Residues 1 to 306 of 306 are 96.07 pct identical to residues 1 to 306 of 306 from GenPept.129 : >emb|CAC34669.1| (AX087925) unnamed protein product [Salmonella typhi]; ribokinase 302651 1036407 c0331 Escherichia coli CFT073 ribokinase NP_752275.1 301731 D 199310 CDS NP_752276.1 26246237 1036394 302679..303995 1 NC_004431.1 Residues 1 to 438 of 438 are 96.11 pct identical to residues 1 to 438 of 438 from GenPept.129 : >gb|AAL22650.1| (AE008876) L-fucose permease [Salmonella typhimurium LT2]; L-fucose permease 303995 1036394 c0332 Escherichia coli CFT073 L-fucose permease NP_752276.1 302679 D 199310 CDS NP_752277.1 26246238 1036399 304007..305020 1 NC_004431.1 Residues 1 to 336 of 337 are 83.03 pct identical to residues 1 to 336 of 337 from GenPept.129 : >gb|AAL22649.1| (AE008876) cytoplasmic protein [Salmonella typhimurium LT2]; cytoplasmic protein 305020 1036399 c0333 Escherichia coli CFT073 cytoplasmic protein NP_752277.1 304007 D 199310 CDS NP_752278.1 26246239 1036393 complement(305943..307199) 1 NC_004431.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 307199 ulaA 1036393 ulaA Escherichia coli CFT073 PTS system ascorbate-specific transporter subunit IIC NP_752278.1 305943 R 199310 CDS NP_752279.1 26246240 1036389 complement(307212..307499) 1 NC_004431.1 Residues 1 to 95 of 95 are 96.84 pct identical to residues 1 to 95 of 95 from GenPept.129 : >gb|AAK27336.1| (AF286670) unknown [Escherichia coli]; hypothetical protein 307499 1036389 c0335 Escherichia coli CFT073 hypothetical protein NP_752279.1 307212 R 199310 CDS NP_752280.1 26246241 1036383 complement(307515..307958) 1 NC_004431.1 EIIA-(C)MTL; Escherichia coli K-12 ortholog: b2934; Escherichia coli O157:H7 ortholog: z4278; PTS system, mannitol (Cryptic)-specific IIA component 307958 1036383 c0336 Escherichia coli CFT073 PTS system, mannitol (Cryptic)-specific IIA component NP_752280.1 307515 R 199310 CDS NP_752281.1 26246242 1036376 308229..309260 1 NC_004431.1 Residues 12 to 307 of 343 are 33.11 pct identical to residues 5 to 298 of 313 from MG1655 : b3438; hypothetical protein 309260 1036376 c0337 Escherichia coli CFT073 hypothetical protein NP_752281.1 308229 D 199310 CDS NP_752282.1 26246243 1036388 complement(309547..309678) 1 NC_004431.1 hypothetical protein 309678 1036388 c0338 Escherichia coli CFT073 hypothetical protein NP_752282.1 309547 R 199310 CDS NP_752283.1 26246244 1036382 complement(309763..309915) 1 NC_004431.1 hypothetical protein 309915 1036382 c0339 Escherichia coli CFT073 hypothetical protein NP_752283.1 309763 R 199310 CDS NP_752284.1 26246245 1036385 309979..310638 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1635; hypothetical protein 310638 1036385 c0340 Escherichia coli CFT073 hypothetical protein NP_752284.1 309979 D 199310 CDS NP_752285.1 26246246 1036373 complement(310629..310817) 1 NC_004431.1 hypothetical protein 310817 1036373 c0341 Escherichia coli CFT073 hypothetical protein NP_752285.1 310629 R 199310 CDS NP_752286.1 26246247 1036378 312645..322295 1 NC_004431.1 Residues 9 to 3039 of 3216 are 32.79 pct identical to residues 52 to 3078 of 3295 from GenPept.129 : >emb|CAC89456.1| (AJ414143) adhesin [Yersinia pestis]; ShlA/HecA/FhaA exofamily protein 322295 1036378 c0345 Escherichia coli CFT073 ShlA/HecA/FhaA exofamily protein NP_752286.1 312645 D 199310 CDS NP_752287.1 26246248 1040030 323695..323937 1 NC_004431.1 hypothetical protein 323937 1040030 c0348 Escherichia coli CFT073 hypothetical protein NP_752287.1 323695 D 199310 CDS NP_752288.1 26246249 1036461 324082..325206 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2082; transposase 325206 1036461 c0349 Escherichia coli CFT073 transposase NP_752288.1 324082 D 199310 CDS NP_752289.1 26246250 1036227 complement(326209..330324) 1 NC_004431.1 Residues 1 to 1371 of 1371 are 96.28 pct identical to residues 1 to 1372 of 1372 from GenPept.129 : >gb|AAD23953.1|AF097644_1 (AF097644) Pic serine protease precursor [Escherichia coli]; Pic serine protease 330324 1036227 c0350 Escherichia coli CFT073 Pic serine protease NP_752289.1 326209 R 199310 CDS NP_752290.1 26246251 1036363 330391..330552 1 NC_004431.1 hypothetical protein 330552 1036363 c0351 Escherichia coli CFT073 hypothetical protein NP_752290.1 330391 D 199310 CDS NP_752291.1 26246252 1036358 complement(331417..331623) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1647; partial transposase 331623 1036358 c0352 Escherichia coli CFT073 partial transposase NP_752291.1 331417 R 199310 CDS NP_752292.1 26246253 1036360 complement(332304..332630) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 332630 1036360 c0354 Escherichia coli CFT073 hypothetical protein NP_752292.1 332304 R 199310 CDS NP_752293.1 26246254 1036361 333750..334046 1 NC_004431.1 Residues 2 to 98 of 98 are 83.50 pct identical to residues 166 to 262 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 334046 1036361 c0355 Escherichia coli CFT073 hypothetical protein NP_752293.1 333750 D 199310 CDS NP_752294.1 26246255 1036356 334492..334875 1 NC_004431.1 Residues 1 to 127 of 127 are 89.31 pct identical to residues 409 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 334875 1036356 c0357 Escherichia coli CFT073 hypothetical protein NP_752294.1 334492 D 199310 CDS NP_752295.1 26246256 1036349 334872..335351 1 NC_004431.1 hypothetical protein 335351 1036349 c0358 Escherichia coli CFT073 hypothetical protein NP_752295.1 334872 D 199310 CDS NP_752296.1 26246257 1036355 complement(335169..335291) 1 NC_004431.1 Residues 1 to 38 of 40 are 65.78 pct identical to residues 1 to 38 of 173 from GenPept.129 : >gb|AAK29065.1|AF345899_1 (AF345899) OrfA [Klebsiella pneumoniae]; hypothetical protein 335291 1036355 c0359 Escherichia coli CFT073 hypothetical protein NP_752296.1 335169 R 199310 CDS NP_752297.1 26246258 1036346 336046..337293 1 NC_004431.1 Residues 93 to 374 of 415 are 22.55 pct identical to residues 108 to 400 of 445 from GenPept.129 : >gb|AAF94774.1| (AE004240) agglutination protein [Vibrio cholerae]; hypothetical protein 337293 1036346 c0360 Escherichia coli CFT073 hypothetical protein NP_752297.1 336046 D 199310 CDS NP_752298.1 26246259 1036345 337318..339465 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0634; cytoplasmic membrane export protein 339465 1036345 c0361 Escherichia coli CFT073 cytoplasmic membrane export protein NP_752298.1 337318 D 199310 CDS NP_752299.1 26246260 1036351 339511..340773 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0635; membrane spanning export protein 340773 1036351 c0362 Escherichia coli CFT073 membrane spanning export protein NP_752299.1 339511 D 199310 CDS NP_752300.1 26246261 1036339 340972..345804 1 NC_004431.1 Residues 83 to 1160 of 1610 are 23.56 pct identical to residues 3030 to 4053 of 4106 from GenPept.129 : >emb|CAD18331.1| (AL646083) HEMAGGLUTININ/HEMOLYSIN-RELATED PROTEIN [Ralstonia solanacearum]; RTX family exoprotein A gene 345804 1036339 c0363 Escherichia coli CFT073 RTX family exoprotein A gene NP_752300.1 340972 D 199310 CDS NP_752301.1 26246262 1036344 345925..346407 1 NC_004431.1 Residues 1 to 156 of 160 are 33.12 pct identical to residues 1 to 157 of 157 from GenPept.129 : >gb|AAL31494.1|AF399847_3 (AF399847) ORF-156F [Escherichia coli]; hypothetical protein 346407 1036344 c0364 Escherichia coli CFT073 hypothetical protein NP_752301.1 345925 D 199310 CDS NP_752302.1 26246263 1039792 346408..346938 1 NC_004431.1 hypothetical protein 346938 1039792 c0365 Escherichia coli CFT073 hypothetical protein NP_752302.1 346408 D 199310 CDS NP_752303.1 26246264 1036350 complement(346889..347158) 1 NC_004431.1 hypothetical protein 347158 1036350 c0366 Escherichia coli CFT073 hypothetical protein NP_752303.1 346889 R 199310 CDS NP_752304.1 26246265 1036336 complement(347299..347775) 1 NC_004431.1 Residues 14 to 152 of 158 are 29.11 pct identical to residues 6 to 160 of 160 from GenPept.129 : >emb|CAA79750.1| (Z21626) transposase [Geobacillus stearothermophilus]; hypothetical protein 347775 1036336 c0367 Escherichia coli CFT073 hypothetical protein NP_752304.1 347299 R 199310 CDS NP_752305.1 26246266 1036337 348228..348353 1 NC_004431.1 hypothetical protein 348353 1036337 c0368 Escherichia coli CFT073 hypothetical protein NP_752305.1 348228 D 199310 CDS NP_752306.1 26246267 1035094 complement(348625..349404) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0219; Escherichia coli O157:H7 ortholog: z0276; hypothetical protein 349404 yafV 1035094 yafV Escherichia coli CFT073 hypothetical protein NP_752306.1 348625 R 199310 CDS NP_752307.1 26246268 1036338 349549..350022 1 NC_004431.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 350022 ykfE 1036338 ykfE Escherichia coli CFT073 C-lysozyme inhibitor NP_752307.1 349549 D 199310 CDS NP_752308.2 161486314 1040416 complement(350065..352509) 1 NC_004431.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 352509 fadE 1040416 fadE Escherichia coli CFT073 acyl-CoA dehydrogenase NP_752308.2 350065 R 199310 CDS NP_752309.2 161486313 1036332 352749..353327 1 NC_004431.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 353327 gmhA 1036332 gmhA Escherichia coli CFT073 phosphoheptose isomerase NP_752309.2 352749 D 199310 CDS NP_752310.1 26246271 1035969 353517..354299 1 NC_004431.1 Escherichia coli K-12 ortholog: b0223; Escherichia coli O157:H7 ortholog: z0281; hypothetical protein 354299 yafJ 1035969 yafJ Escherichia coli CFT073 hypothetical protein NP_752310.1 353517 D 199310 CDS NP_752311.1 26246272 1036334 complement(354270..355010) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0224; Escherichia coli O157:H7 ortholog: z0282; hypothetical protein 355010 yafK 1036334 yafK Escherichia coli CFT073 hypothetical protein NP_752311.1 354270 R 199310 CDS NP_752312.1 26246273 1036327 complement(355267..355404) 1 NC_004431.1 hypothetical protein 355404 1036327 c0375 Escherichia coli CFT073 hypothetical protein NP_752312.1 355267 R 199310 CDS NP_752313.1 26246274 1036330 355379..356071 1 NC_004431.1 Escherichia coli K-12 ortholog: b0227; Escherichia coli O157:H7 ortholog: z0287; lipoprotein yafL 356071 yafL 1036330 yafL Escherichia coli CFT073 lipoprotein yafL NP_752313.1 355379 D 199310 CDS NP_752314.1 26246275 1036328 complement(356346..358085) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0229; Escherichia coli O157:H7 ortholog: z0290; FhiA protein 358085 fhiA 1036328 fhiA Escherichia coli CFT073 FhiA protein NP_752314.1 356346 R 199310 CDS NP_752315.1 26246276 1039617 358027..358815 1 NC_004431.1 Escherichia coli K-12 ortholog: b0230; Escherichia coli O157:H7 ortholog: z0291; hypothetical protein 358815 mbhA 1039617 mbhA Escherichia coli CFT073 hypothetical protein NP_752315.1 358027 D 199310 CDS NP_752316.1 26246277 1036320 358886..359941 1 NC_004431.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 359941 dinP 1036320 dinP Escherichia coli CFT073 DNA polymerase IV NP_752316.1 358886 D 199310 CDS NP_752317.1 26246278 1036325 359938..360390 1 NC_004431.1 Escherichia coli K-12 ortholog: b0234; Escherichia coli O157:H7 ortholog: z0295; hypothetical protein 360390 yafP 1036325 yafP Escherichia coli CFT073 hypothetical protein NP_752317.1 359938 D 199310 CDS NP_752318.2 161486312 1036322 360580..361719 1 NC_004431.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 361719 1036322 c0381 Escherichia coli CFT073 hypothetical protein NP_752318.2 360580 D 199310 CDS NP_752319.2 161486311 1036323 361830..362330 1 NC_004431.1 similar to release factor 1 and 2; peptide chain release factor-like protein 362330 prfH 1036323 prfH Escherichia coli CFT073 peptide chain release factor-like protein NP_752319.2 361830 D 199310 CDS NP_752320.1 26246281 1036317 complement(362387..363844) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0237; Escherichia coli O157:H7 ortholog: z0298; aminoacyl-histidine dipeptidase 363844 pepD 1036317 pepD Escherichia coli CFT073 aminoacyl-histidine dipeptidase NP_752320.1 362387 R 199310 CDS NP_752321.1 26246282 1036319 364105..364563 1 NC_004431.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 364563 gpt 1036319 gpt Escherichia coli CFT073 xanthine-guanine phosphoribosyltransferase NP_752321.1 364105 D 199310 CDS NP_752322.1 26246283 1036311 complement(364237..364689) 1 NC_004431.1 hypothetical protein 364689 1036311 c0385 Escherichia coli CFT073 hypothetical protein NP_752322.1 364237 R 199310 CDS NP_752323.1 26246284 1036321 364655..365899 1 NC_004431.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 365899 frsA 1036321 frsA Escherichia coli CFT073 fermentation/respiration switch protein NP_752323.1 364655 D 199310 CDS NP_752324.1 26246285 1036309 365957..366358 1 NC_004431.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 366358 crl 1036309 crl Escherichia coli CFT073 DNA-binding transcriptional regulator Crl NP_752324.1 365957 D 199310 CDS NP_752325.1 26246286 1036315 complement(366397..367458) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0241; Escherichia coli O157:H7 ortholog: z0302; outer membrane phosphoporin protein E 367458 phoE 1036315 phoE Escherichia coli CFT073 outer membrane phosphoporin protein E NP_752325.1 366397 R 199310 CDS NP_752326.2 161486310 1036313 367741..368844 1 NC_004431.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 368844 proB 1036313 proB Escherichia coli CFT073 gamma-glutamyl kinase NP_752326.2 367741 D 199310 CDS NP_752327.1 26246288 1036306 368856..370109 1 NC_004431.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 370109 proA 1036306 proA Escherichia coli CFT073 gamma-glutamyl phosphate reductase NP_752327.1 368856 D 199310 CDS NP_752328.1 26246289 1036310 370454..370792 1 NC_004431.1 Residues 1 to 111 of 112 are 63.06 pct identical to residues 1 to 111 of 404 from GenPept.129 : >emb|CAC89731.1| (AJ414145) integrase [Yersinia pestis]; CP4-like integrase 370792 1036310 c0391 Escherichia coli CFT073 CP4-like integrase NP_752328.1 370454 D 199310 CDS NP_752329.1 26246290 1036305 complement(371227..371751) 1 NC_004431.1 Residues 11 to 172 of 174 are 46.91 pct identical to residues 1 to 162 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; hypothetical protein 371751 1036305 c0392 Escherichia coli CFT073 hypothetical protein NP_752329.1 371227 R 199310 CDS NP_752330.1 26246291 1034958 complement(371877..376007) 1 NC_004431.1 Residues 1 to 1376 of 1376 are 79.04 pct identical to residues 1 to 1377 of 1377 from GenPept.129 : >emb|CAA11507.1| (AJ223631) haemoglobin protease [Escherichia coli]; hemoglobin protease 376007 1034958 c0393 Escherichia coli CFT073 hemoglobin protease NP_752330.1 371877 R 199310 CDS NP_752331.1 26246292 1039704 376320..376517 1 NC_004431.1 hypothetical protein 376517 1039704 c0394 Escherichia coli CFT073 hypothetical protein NP_752331.1 376320 D 199310 CDS NP_752332.1 26246293 1036307 376435..376560 1 NC_004431.1 hypothetical protein 376560 1036307 c0395 Escherichia coli CFT073 hypothetical protein NP_752332.1 376435 D 199310 CDS NP_752333.1 26246294 1036303 376600..376815 1 NC_004431.1 IS1a/IS1b/IS1c/IS1d; Escherichia coli K-12 ortholog: b3444; insertion element IS1 1/2/3/5/6 protein insA 376815 1036303 c0396 Escherichia coli CFT073 insertion element IS1 1/2/3/5/6 protein insA NP_752333.1 376600 D 199310 CDS NP_752334.1 26246295 1036302 377117..377293 1 NC_004431.1 Residues 1 to 58 of 58 are 87.93 pct identical to residues 74 to 131 of 131 from GenPept.129 : >gb|AAF28142.1|AF153317_40 (AF153317) InsB [Shigella dysenteriae]; InsB protein 377293 1036302 c0397 Escherichia coli CFT073 InsB protein NP_752334.1 377117 D 199310 CDS NP_752335.1 26246296 1036304 377672..377854 1 NC_004431.1 hypothetical protein 377854 1036304 c0398 Escherichia coli CFT073 hypothetical protein NP_752335.1 377672 D 199310 CDS NP_752336.1 26246297 1036298 378117..378731 1 NC_004431.1 Escherichia coli K-12 ortholog: b0287; Escherichia coli O157:H7 ortholog: z0353; hypothetical protein 378731 yagU 1036298 yagU Escherichia coli CFT073 hypothetical protein NP_752336.1 378117 D 199310 CDS NP_752337.1 26246298 1036301 complement(379616..380371) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0289; Escherichia coli O157:H7 ortholog: z0356; hypothetical protein 380371 yagV 1036301 yagV Escherichia coli CFT073 hypothetical protein NP_752337.1 379616 R 199310 CDS NP_752338.1 26246299 1036297 complement(380295..381938) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0290; Escherichia coli O157:H7 ortholog: z0357; hypothetical protein 381938 yagW 1036297 yagW Escherichia coli CFT073 hypothetical protein NP_752338.1 380295 R 199310 CDS NP_752339.1 26246300 1036299 complement(381928..384453) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0291; Escherichia coli O157:H7 ortholog: z0358; hypothetical protein 384453 yagX 1036299 yagX Escherichia coli CFT073 hypothetical protein NP_752339.1 381928 R 199310 CDS NP_752340.1 26246301 1040494 complement(384479..385195) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0292; Escherichia coli O157:H7 ortholog: z0359; hypothetical protein 385195 yagY 1040494 yagY Escherichia coli CFT073 hypothetical protein NP_752340.1 384479 R 199310 CDS NP_752341.1 26246302 1036296 complement(385204..385791) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0293; Escherichia coli O157:H7 ortholog: z0360; hypothetical protein 385791 matB 1036296 matB Escherichia coli CFT073 hypothetical protein NP_752341.1 385204 R 199310 CDS NP_752342.1 26246303 1036295 complement(385866..386456) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0294; Escherichia coli O157:H7 ortholog: z0361; hypothetical protein 386456 matA 1036295 matA Escherichia coli CFT073 hypothetical protein NP_752342.1 385866 R 199310 CDS NP_752343.1 26246304 1036291 complement(387492..387635) 1 NC_004431.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 387635 rpmJ 1036291 rpmJ Escherichia coli CFT073 50S ribosomal protein L36 NP_752343.1 387492 R 199310 CDS NP_752344.2 161486309 1040414 complement(387632..387895) 1 NC_004431.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 387895 rpmE2 1040414 rpmE2 Escherichia coli CFT073 50S ribosomal protein L31 NP_752344.2 387632 R 199310 CDS NP_752345.1 26246306 1036294 complement(388835..388978) 1 NC_004431.1 Residues 1 to 47 of 47 are 91.48 pct identical to residues 334 to 380 of 380 from GenPept.129 : >gb|AAG54626.1|AE005207_1 (AE005207) oxidoreductase [Escherichia coli O157:H7 EDL933]; hypothetical protein 388978 1036294 c0408 Escherichia coli CFT073 hypothetical protein NP_752345.1 388835 R 199310 CDS NP_752346.1 26246307 1036293 complement(388990..389979) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0369; oxidoreductase 389979 1036293 c0409 Escherichia coli CFT073 oxidoreductase NP_752346.1 388990 R 199310 CDS NP_752347.1 26246308 1036292 complement(390151..391071) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1327; Escherichia coli O157:H7 ortholog: z0370; hypothetical protein 391071 1036292 c0410 Escherichia coli CFT073 hypothetical protein NP_752347.1 390151 R 199310 CDS NP_752348.1 26246309 1036796 391165..392154 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0371; LysR family transcriptional regulator 392154 1036796 c0411 Escherichia coli CFT073 LysR family transcriptional regulator NP_752348.1 391165 D 199310 CDS NP_752349.1 26246310 1036288 392279..393247 1 NC_004431.1 Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 393247 1036288 c0412 Escherichia coli CFT073 transcriptional regulator YcjZ NP_752349.1 392279 D 199310 CDS NP_752350.1 26246311 1035013 complement(393278..394267) 1 NC_004431.1 Residues 6 to 290 of 329 are 50.51 pct identical to residues 13 to 301 of 307 from SwissProt.40 : >sp|P40691|A115_TOBAC AUXIN-INDUCED PROTEIN PCNT115; aldo/keto reductase 394267 1035013 c0413 Escherichia coli CFT073 aldo/keto reductase NP_752350.1 393278 R 199310 CDS NP_752351.1 26246312 1036290 complement(394294..395145) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3012; Escherichia coli O157:H7 ortholog: z0374; 2,5-diketo-D-gluconate reductase A 395145 1036290 c0414 Escherichia coli CFT073 2,5-diketo-D-gluconate reductase A NP_752351.1 394294 R 199310 CDS NP_752352.1 26246313 1036283 395711..399961 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0375; adhesin 399961 eaeH 1036283 eaeH Escherichia coli CFT073 adhesin NP_752352.1 395711 D 199310 CDS NP_752353.1 26246314 1036289 complement(400086..400976) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0300; Escherichia coli O157:H7 ortholog: z0376; transcriptional regulator YkgA 400976 ykgA 1036289 ykgA Escherichia coli CFT073 transcriptional regulator YkgA NP_752353.1 400086 R 199310 CDS NP_752354.1 26246315 1036281 401176..402060 1 NC_004431.1 Escherichia coli K-12 ortholog: b3012; Escherichia coli O157:H7 ortholog: z0377; 2,5-diketo-D-gluconate reductase A 402060 1036281 c0417 Escherichia coli CFT073 2,5-diketo-D-gluconate reductase A NP_752354.1 401176 D 199310 CDS NP_752355.1 26246316 1040057 complement(402220..402822) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0301; Escherichia coli O157:H7 ortholog: z0378; hypothetical protein 402822 ykgB 1040057 ykgB Escherichia coli CFT073 hypothetical protein NP_752355.1 402220 R 199310 CDS NP_752356.1 26246317 1036275 complement(402825..403076) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0303; Escherichia coli O157:H7 ortholog: z0380; hypothetical protein 403076 ykgI 1036275 ykgI Escherichia coli CFT073 hypothetical protein NP_752356.1 402825 R 199310 CDS NP_752357.2 161486308 1035927 complement(403170..404495) 1 NC_004431.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 404495 ykgC 1035927 ykgC Escherichia coli CFT073 pyridine nucleotide-disulfide oxidoreductase NP_752357.2 403170 R 199310 CDS NP_752358.1 26246319 1036282 404671..405576 1 NC_004431.1 Escherichia coli K-12 ortholog: b0305; Escherichia coli O157:H7 ortholog: z0382; transcriptional regulator YkgD 405576 ykgD 1036282 ykgD Escherichia coli CFT073 transcriptional regulator YkgD NP_752358.1 404671 D 199310 CDS NP_752359.1 26246320 1036277 406102..406821 1 NC_004431.1 Escherichia coli K-12 ortholog: b0306; Escherichia coli O157:H7 ortholog: z0384; hypothetical protein 406821 ykgE 1036277 ykgE Escherichia coli CFT073 hypothetical protein NP_752359.1 406102 D 199310 CDS NP_752360.1 26246321 1036266 406832..408259 1 NC_004431.1 Escherichia coli K-12 ortholog: b0307; Escherichia coli O157:H7 ortholog: z0385; electron transport protein ykgF 408259 ykgF 1036266 ykgF Escherichia coli CFT073 electron transport protein ykgF NP_752360.1 406832 D 199310 CDS NP_752361.3 347357904 1036269 408099..408947 1 NC_004431.1 Escherichia coli K-12 ortholog: b0308; Escherichia coli O157:H7 ortholog: z0386; hypothetical protein 408947 ykgG 1036269 ykgG Escherichia coli CFT073 hypothetical protein NP_752361.3 408099 D 199310 CDS NP_752362.1 26246323 1036270 complement(409190..409858) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0310; Escherichia coli O157:H7 ortholog: z0388; hypothetical protein 409858 ykgH 1036270 ykgH Escherichia coli CFT073 hypothetical protein NP_752362.1 409190 R 199310 CDS NP_752363.1 26246324 1036267 complement(410042..412372) 1 NC_004431.1 Residues 7 to 372 of 776 are 88.31 pct identical to residues 1 to 366 of 369 from GenPept.129 : >gb|AAG54646.1|AE005209_2 (AE005209) Z0390 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 412372 1036267 c0426 Escherichia coli CFT073 hypothetical protein NP_752363.1 410042 R 199310 CDS NP_752364.1 26246325 1036264 complement(412381..413142) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0391; hypothetical protein 413142 1036264 c0427 Escherichia coli CFT073 hypothetical protein NP_752364.1 412381 R 199310 CDS NP_752365.1 26246326 1038753 complement(413296..414000) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0392; hypothetical protein 414000 1038753 c0428 Escherichia coli CFT073 hypothetical protein NP_752365.1 413296 R 199310 CDS NP_752366.1 26246327 1036259 complement(413972..414127) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0393; hypothetical protein 414127 1036259 c0429 Escherichia coli CFT073 hypothetical protein NP_752366.1 413972 R 199310 CDS NP_752367.1 26246328 1036265 complement(414420..415022) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4312; Type 1 fimbriae regulatory protein fimB 415022 1036265 c0430 Escherichia coli CFT073 Type 1 fimbriae regulatory protein fimB NP_752367.1 414420 R 199310 CDS NP_752368.2 161486306 1036260 complement(416069..417739) 1 NC_004431.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 417739 betA 1036260 betA Escherichia coli CFT073 choline dehydrogenase NP_752368.2 416069 R 199310 CDS NP_752369.1 26246330 1036263 complement(417753..419228) 1 NC_004431.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 419228 betB 1036263 betB Escherichia coli CFT073 betaine aldehyde dehydrogenase NP_752369.1 417753 R 199310 CDS NP_752370.1 26246331 1036258 complement(419239..419844) 1 NC_004431.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 419844 betI 1036258 betI Escherichia coli CFT073 transcriptional regulator BetI NP_752370.1 419239 R 199310 CDS NP_752371.1 26246332 1036262 419955..421988 1 NC_004431.1 proton-motive-force-driven choline transporter; choline transport protein BetT 421988 betT 1036262 betT Escherichia coli CFT073 choline transport protein BetT NP_752371.1 419955 D 199310 CDS NP_752372.1 26246333 1036256 422858..423952 1 NC_004431.1 Escherichia coli K-12 ortholog: b0315; Escherichia coli O157:H7 ortholog: z0403; hypothetical protein 423952 1036256 c0435 Escherichia coli CFT073 hypothetical protein NP_752372.1 422858 D 199310 CDS NP_752373.1 26246334 1036257 complement(423994..424926) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0316; Escherichia coli O157:H7 ortholog: z0405; transcriptional regulator YahB 424926 yahB 1036257 yahB Escherichia coli CFT073 transcriptional regulator YahB NP_752373.1 423994 R 199310 CDS NP_752374.1 26246335 1034971 complement(425018..425515) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0317; Escherichia coli O157:H7 ortholog: z0406; hypothetical protein 425515 yahC 1034971 yahC Escherichia coli CFT073 hypothetical protein NP_752374.1 425018 R 199310 CDS NP_752375.1 26246336 1036727 425592..425834 1 NC_004431.1 hypothetical protein 425834 1036727 c0438 Escherichia coli CFT073 hypothetical protein NP_752375.1 425592 D 199310 CDS NP_752376.1 26246337 1036250 425773..426378 1 NC_004431.1 Escherichia coli K-12 ortholog: b0318; Escherichia coli O157:H7 ortholog: z0407; ankyrin repeat-containing protein 426378 yahD 1036250 yahD Escherichia coli CFT073 ankyrin repeat-containing protein NP_752376.1 425773 D 199310 CDS NP_752377.1 26246338 1036253 426418..427281 1 NC_004431.1 Escherichia coli K-12 ortholog: b0319; Escherichia coli O157:H7 ortholog: z0408; hypothetical protein 427281 yahE 1036253 yahE Escherichia coli CFT073 hypothetical protein NP_752377.1 426418 D 199310 CDS NP_752378.1 26246339 1036255 427271..428818 1 NC_004431.1 Escherichia coli K-12 ortholog: b0320; Escherichia coli O157:H7 ortholog: z0409; hypothetical protein 428818 1036255 c0441 Escherichia coli CFT073 hypothetical protein NP_752378.1 427271 D 199310 CDS NP_752379.1 26246340 1036252 430662..431612 1 NC_004431.1 forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate; carbamate kinase 431612 1036252 c0444 Escherichia coli CFT073 carbamate kinase NP_752379.1 430662 D 199310 CDS NP_752380.1 26246341 1036244 431622..433004 1 NC_004431.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 433004 yahJ 1036244 yahJ Escherichia coli CFT073 deaminase NP_752380.1 431622 D 199310 CDS NP_752381.1 26246342 1036247 complement(433226..433381) 1 NC_004431.1 hypothetical protein 433381 1036247 c0446 Escherichia coli CFT073 hypothetical protein NP_752381.1 433226 R 199310 CDS NP_752382.1 26246343 1036286 433381..434430 1 NC_004431.1 Escherichia coli K-12 ortholog: b0325; Escherichia coli O157:H7 ortholog: z0420; hypothetical protein 434430 yahK 1036286 yahK Escherichia coli CFT073 hypothetical protein NP_752382.1 433381 D 199310 CDS NP_752383.1 26246344 1036230 complement(435312..435986) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0328; Escherichia coli O157:H7 ortholog: z0424; hypothetical protein 435986 yahN 1036230 yahN Escherichia coli CFT073 hypothetical protein NP_752383.1 435312 R 199310 CDS NP_752384.1 26246345 1036242 436133..436408 1 NC_004431.1 Escherichia coli K-12 ortholog: b0329; Escherichia coli O157:H7 ortholog: z0425; hypothetical protein 436408 yahO 1036242 yahO Escherichia coli CFT073 hypothetical protein NP_752384.1 436133 D 199310 CDS NP_752385.1 26246346 1036232 complement(436509..438095) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0330; Escherichia coli O157:H7 ortholog: z0426; propionate catabolism operon regulatory protein 438095 prpR 1036232 prpR Escherichia coli CFT073 propionate catabolism operon regulatory protein NP_752385.1 436509 R 199310 CDS NP_752386.1 26246347 1039779 438334..439224 1 NC_004431.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 439224 prpB 1039779 prpB Escherichia coli CFT073 2-methylisocitrate lyase NP_752386.1 438334 D 199310 CDS NP_752387.1 26246348 1036234 439384..440553 1 NC_004431.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 440553 prpC 1036234 prpC Escherichia coli CFT073 methylcitrate synthase NP_752387.1 439384 D 199310 CDS NP_752388.1 26246349 1037564 440587..442038 1 NC_004431.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 442038 prpD 1037564 prpD Escherichia coli CFT073 2-methylcitrate dehydratase NP_752388.1 440587 D 199310 CDS NP_752389.1 26246350 1038450 442078..443964 1 NC_004431.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 443964 prpE 1038450 prpE Escherichia coli CFT073 propionyl-CoA synthetase NP_752389.1 442078 D 199310 CDS NP_752390.1 26246351 1036222 444289..445548 1 NC_004431.1 Escherichia coli K-12 ortholog: b0336; Escherichia coli O157:H7 ortholog: z0432; cytosine permease 445548 codB 1036222 codB Escherichia coli CFT073 cytosine permease NP_752390.1 444289 D 199310 CDS NP_752391.1 26246352 1040512 445523..446821 1 NC_004431.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 446821 codA 1040512 codA Escherichia coli CFT073 cytosine deaminase NP_752391.1 445523 D 199310 CDS NP_752392.1 26246353 1036231 complement(446942..447604) 1 NC_004431.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 447604 lacA 1036231 lacA Escherichia coli CFT073 galactoside O-acetyltransferase NP_752392.1 446942 R 199310 CDS NP_752393.1 26246354 1036217 complement(447619..448872) 1 NC_004431.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 448872 lacY 1036217 lacY Escherichia coli CFT073 galactoside permease NP_752393.1 447619 R 199310 CDS NP_752394.1 26246355 1036228 complement(448924..451998) 1 NC_004431.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 451998 lacZ 1036228 lacZ Escherichia coli CFT073 beta-D-galactosidase NP_752394.1 448924 R 199310 CDS NP_752395.1 26246356 1040087 complement(452122..452388) 1 NC_004431.1 Residues 12 to 88 of 88 are 88.31 pct identical to residues 284 to 360 of 360 from GenPept.129 : >gb|AAL59004.1| (AY070365) Lac repressor [Expression vector pFHC2102]; LacI protein 452388 1040087 c0460 Escherichia coli CFT073 LacI protein NP_752395.1 452122 R 199310 CDS NP_752396.3 347357903 1036225 453388..453945 1 NC_004431.1 Escherichia coli K-12 ortholog: b0354; Escherichia coli O157:H7 ortholog: z0454; hypothetical protein 453945 yaiL 1036225 yaiL Escherichia coli CFT073 hypothetical protein NP_752396.3 453388 D 199310 CDS NP_752397.1 26246358 1036215 complement(453448..453999) 1 NC_004431.1 hypothetical protein 453999 1036215 c0463 Escherichia coli CFT073 hypothetical protein NP_752397.1 453448 R 199310 CDS NP_752398.1 26246359 1040106 complement(454173..455006) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0355; Escherichia coli O157:H7 ortholog: z0455; hypothetical protein 455006 yaiM 1040106 yaiM Escherichia coli CFT073 hypothetical protein NP_752398.1 454173 R 199310 CDS NP_752399.1 26246360 1036214 complement(455099..456208) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0356; Escherichia coli O157:H7 ortholog: z0456; alcohol dehydrogenase 456208 adhC 1036214 adhC Escherichia coli CFT073 alcohol dehydrogenase NP_752399.1 455099 R 199310 CDS NP_752400.1 26246361 1036220 complement(456243..456539) 1 NC_004431.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 456539 yaiN 1036220 yaiN Escherichia coli CFT073 regulator protein FrmR NP_752400.1 456243 R 199310 CDS NP_752401.1 26246362 1035951 complement(456705..457478) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0358; hypothetical protein 457478 1035951 c0467 Escherichia coli CFT073 hypothetical protein NP_752401.1 456705 R 199310 CDS NP_752402.1 26246363 1036211 complement(457480..458004) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0359; transferase 458004 1036211 c0468 Escherichia coli CFT073 transferase NP_752402.1 457480 R 199310 CDS NP_752403.1 26246364 1040149 complement(458039..459235) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0363; hypothetical protein 459235 1040149 c0469 Escherichia coli CFT073 hypothetical protein NP_752403.1 458039 R 199310 CDS NP_752404.1 26246365 1036213 complement(459245..459931) 1 NC_004431.1 Residues 55 to 190 of 228 are 94.11 pct identical to residues 1 to 136 of 136 from MG1655 : b0364; hypothetical protein 459931 1036213 c0470 Escherichia coli CFT073 hypothetical protein NP_752404.1 459245 R 199310 CDS NP_752405.1 26246366 1036197 complement(460376..460570) 1 NC_004431.1 hypothetical protein 460570 1036197 c0471 Escherichia coli CFT073 hypothetical protein NP_752405.1 460376 R 199310 CDS NP_752406.3 347357902 1036201 460467..461486 1 NC_004431.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 461486 tauA 1036201 tauA Escherichia coli CFT073 taurine transporter substrate binding subunit NP_752406.3 460467 D 199310 CDS NP_752407.1 26246368 1036206 461499..462266 1 NC_004431.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 462266 tauB 1036206 tauB Escherichia coli CFT073 taurine transporter ATP-binding subunit NP_752407.1 461499 D 199310 CDS NP_752408.1 26246369 1036203 complement(461900..462214) 1 NC_004431.1 hypothetical protein 462214 1036203 c0474 Escherichia coli CFT073 hypothetical protein NP_752408.1 461900 R 199310 CDS NP_752409.1 26246370 1036195 462263..463090 1 NC_004431.1 Escherichia coli K-12 ortholog: b0367; Escherichia coli O157:H7 ortholog: z0466; taurine transporter subunit 463090 tauC 1036195 tauC Escherichia coli CFT073 taurine transporter subunit NP_752409.1 462263 D 199310 CDS NP_752410.1 26246371 1036193 463087..463938 1 NC_004431.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 463938 tauD 1036193 tauD Escherichia coli CFT073 taurine dioxygenase NP_752410.1 463087 D 199310 CDS NP_752411.1 26246372 1036196 complement(463978..464985) 1 NC_004431.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 464985 hemB 1036196 hemB Escherichia coli CFT073 delta-aminolevulinic acid dehydratase NP_752411.1 463978 R 199310 CDS NP_752412.1 26246373 1036198 465478..468465 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0469; SapA-like; structural protein 468465 1036198 c0478 Escherichia coli CFT073 structural protein NP_752412.1 465478 D 199310 CDS NP_752413.1 26246374 1036185 468506..469174 1 NC_004431.1 Escherichia coli K-12 ortholog: b0375; Escherichia coli O157:H7 ortholog: z0470; DNA-binding transcriptional regulator 469174 yaiV 1036185 yaiV Escherichia coli CFT073 DNA-binding transcriptional regulator NP_752413.1 468506 D 199310 CDS NP_752414.1 26246375 1036189 complement(469175..470332) 1 NC_004431.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 470332 yaiH 1036189 yaiH Escherichia coli CFT073 beta-lactam binding protein AmpH NP_752414.1 469175 R 199310 CDS NP_752415.1 26246376 1036184 470470..470664 1 NC_004431.1 hypothetical protein 470664 1036184 c0481 Escherichia coli CFT073 hypothetical protein NP_752415.1 470470 D 199310 CDS NP_752416.1 26246377 1036188 470678..471904 1 NC_004431.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 471904 sbmA 1036188 sbmA Escherichia coli CFT073 transport protein NP_752416.1 470678 D 199310 CDS NP_752417.1 26246378 1036177 471917..473011 1 NC_004431.1 Escherichia coli K-12 ortholog: b0378; Escherichia coli O157:H7 ortholog: z0474; hypothetical protein 473011 yaiW 1036177 yaiW Escherichia coli CFT073 hypothetical protein NP_752417.1 471917 D 199310 CDS NP_752418.1 26246379 1036182 complement(473070..473378) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0379; Escherichia coli O157:H7 ortholog: z0475; hypothetical protein 473378 yaiY 1036182 yaiY Escherichia coli CFT073 hypothetical protein NP_752418.1 473070 R 199310 CDS NP_752419.1 26246380 1036175 473308..473442 1 NC_004431.1 hypothetical protein 473442 1036175 c0485 Escherichia coli CFT073 hypothetical protein NP_752419.1 473308 D 199310 CDS NP_752420.1 26246381 1036183 473506..473850 1 NC_004431.1 Escherichia coli K-12 ortholog: b0380; Escherichia coli O157:H7 ortholog: z0476; hypothetical protein 473850 yaiZ 1036183 yaiZ Escherichia coli CFT073 hypothetical protein NP_752420.1 473506 D 199310 CDS NP_752421.1 26246382 1036174 complement(473874..474968) 1 NC_004431.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 474968 ddl 1036174 ddl Escherichia coli CFT073 D-alanyl-alanine synthetase A NP_752421.1 473874 R 199310 CDS NP_752422.1 26246383 1036169 475046..475168 1 NC_004431.1 hypothetical protein 475168 1036169 c0488 Escherichia coli CFT073 hypothetical protein NP_752422.1 475046 D 199310 CDS NP_752423.1 26246384 1036178 475431..475691 1 NC_004431.1 Escherichia coli K-12 ortholog: b0382; Escherichia coli O157:H7 ortholog: z0478; hypothetical protein 475691 yaiB 1036178 yaiB Escherichia coli CFT073 hypothetical protein NP_752423.1 475431 D 199310 CDS NP_752424.1 26246385 1036181 475723..477207 1 NC_004431.1 Escherichia coli K-12 ortholog: b0383; Escherichia coli O157:H7 ortholog: z0479; alkaline phosphatase 477207 phoA 1036181 phoA Escherichia coli CFT073 alkaline phosphatase NP_752424.1 475723 D 199310 CDS NP_752425.1 26246386 1036168 477308..477646 1 NC_004431.1 Escherichia coli K-12 ortholog: b0384; Escherichia coli O157:H7 ortholog: z0480; hypothetical protein 477646 psiF 1036168 psiF Escherichia coli CFT073 hypothetical protein NP_752425.1 477308 D 199310 CDS NP_752426.1 26246387 1036170 477748..478863 1 NC_004431.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 478863 adrA 1036170 adrA Escherichia coli CFT073 diguanylate cyclase AdrA NP_752426.1 477748 D 199310 CDS NP_752427.3 347357901 1036167 complement(478880..479797) 1 NC_004431.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 479797 proC 1036167 proC Escherichia coli CFT073 pyrroline-5-carboxylate reductase NP_752427.3 478880 R 199310 CDS NP_752429.1 26246390 1036156 480450..480974 1 NC_004431.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 480974 aroL 1036156 aroL Escherichia coli CFT073 shikimate kinase II NP_752429.1 480450 D 199310 CDS NP_752430.1 26246391 1036164 481024..481215 1 NC_004431.1 Escherichia coli K-12 ortholog: b0389; Escherichia coli O157:H7 ortholog: z0485; hypothetical protein 481215 yaiA 1036164 yaiA Escherichia coli CFT073 hypothetical protein NP_752430.1 481024 D 199310 CDS NP_752431.1 26246392 1036163 481406..481552 1 NC_004431.1 hypothetical protein 481552 1036163 c0497 Escherichia coli CFT073 hypothetical protein NP_752431.1 481406 D 199310 CDS NP_752432.1 26246393 1036157 481473..482150 1 NC_004431.1 Escherichia coli K-12 ortholog: b0390; Escherichia coli O157:H7 ortholog: z0486; hypothetical protein 482150 aroM 1036157 aroM Escherichia coli CFT073 hypothetical protein NP_752432.1 481473 D 199310 CDS NP_752433.1 26246394 1034987 482222..482506 1 NC_004431.1 Escherichia coli K-12 ortholog: b0391; Escherichia coli O157:H7 ortholog: z0487; hypothetical protein 482506 yaiE 1034987 yaiE Escherichia coli CFT073 hypothetical protein NP_752433.1 482222 D 199310 CDS NP_752434.1 26246395 1036155 complement(482610..482765) 1 NC_004431.1 hypothetical protein 482765 1036155 c0500 Escherichia coli CFT073 hypothetical protein NP_752434.1 482610 R 199310 CDS NP_752435.1 26246396 1036139 482714..482995 1 NC_004431.1 Escherichia coli K-12 ortholog: b0392; Escherichia coli O157:H7 ortholog: z0489; hypothetical protein 482995 ykiA 1036139 ykiA Escherichia coli CFT073 hypothetical protein NP_752435.1 482714 D 199310 CDS NP_752436.2 161486301 1036150 complement(483153..484064) 1 NC_004431.1 Required for efficient pilin antigenic variation; recombination associated protein 484064 rdgC 1036150 rdgC Escherichia coli CFT073 recombination associated protein NP_752436.2 483153 R 199310 CDS NP_752437.2 161486300 1036134 484189..485097 1 NC_004431.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 485097 1036134 c0503 Escherichia coli CFT073 fructokinase NP_752437.2 484189 D 199310 CDS NP_752438.1 26246399 1036135 complement(485366..486634) 1 NC_004431.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 486634 araJ 1036135 araJ Escherichia coli CFT073 MFS transport protein AraJ NP_752438.1 485366 R 199310 CDS NP_752439.1 26246400 1036137 complement(486676..489819) 1 NC_004431.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC 489819 sbcC 1036137 sbcC Escherichia coli CFT073 exonuclease SbcC NP_752439.1 486676 R 199310 CDS NP_752440.1 26246401 1036147 complement(489816..491018) 1 NC_004431.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 491018 sbcD 1036147 sbcD Escherichia coli CFT073 exonuclease SbcD NP_752440.1 489816 R 199310 CDS NP_752441.1 26246402 1036126 491004..491135 1 NC_004431.1 hypothetical protein 491135 1036126 c0507 Escherichia coli CFT073 hypothetical protein NP_752441.1 491004 D 199310 CDS NP_752442.1 26246403 1036128 491208..491897 1 NC_004431.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 491897 phoB 1036128 phoB Escherichia coli CFT073 transcriptional regulator PhoB NP_752442.1 491208 D 199310 CDS NP_752443.1 26246404 1036130 491955..493250 1 NC_004431.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 493250 phoR 1036130 phoR Escherichia coli CFT073 phosphate regulon sensor protein NP_752443.1 491955 D 199310 CDS NP_752444.1 26246405 1036119 complement(493463..493612) 1 NC_004431.1 hypothetical protein 493612 1036119 c0510 Escherichia coli CFT073 hypothetical protein NP_752444.1 493463 R 199310 CDS NP_752445.1 26246406 1036122 493657..494976 1 NC_004431.1 LIV-II; Escherichia coli K-12 ortholog: b0401; Escherichia coli O157:H7 ortholog: z0499; branched chain amino acid ABC transporter carrier protein 494976 brnQ 1036122 brnQ Escherichia coli CFT073 branched chain amino acid ABC transporter carrier protein NP_752445.1 493657 D 199310 CDS NP_752446.1 26246407 1036123 495049..496425 1 NC_004431.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 496425 proY 1036123 proY Escherichia coli CFT073 proline-specific permease NP_752446.1 495049 D 199310 CDS NP_752447.1 26246408 1036127 496581..498398 1 NC_004431.1 Escherichia coli K-12 ortholog: b0403; Escherichia coli O157:H7 ortholog: z0501; maltodextrin glucosidase 498398 malZ 1036127 malZ Escherichia coli CFT073 maltodextrin glucosidase NP_752447.1 496581 D 199310 CDS NP_752448.2 161486299 1036110 complement(498403..498984) 1 NC_004431.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase 498984 yajB 1036110 yajB Escherichia coli CFT073 ACP phosphodieterase NP_752448.2 498403 R 199310 CDS NP_752449.1 26246410 1036106 499203..500273 1 NC_004431.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 500273 queA 1036106 queA Escherichia coli CFT073 S-adenosylmethionine:tRNA ribosyltransferase-isomerase NP_752449.1 499203 D 199310 CDS NP_752450.1 26246411 1036109 500328..501455 1 NC_004431.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 501455 tgt 1036109 tgt Escherichia coli CFT073 queuine tRNA-ribosyltransferase NP_752450.1 500328 D 199310 CDS NP_752451.2 161486298 1036111 501478..501810 1 NC_004431.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 501810 yajC 1036111 yajC Escherichia coli CFT073 preprotein translocase subunit YajC NP_752451.2 501478 D 199310 CDS NP_752452.1 26246413 1036102 501838..503685 1 NC_004431.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 503685 secD 1036102 secD Escherichia coli CFT073 preprotein translocase subunit SecD NP_752452.1 501838 D 199310 CDS NP_752453.2 161486297 1036099 503696..504667 1 NC_004431.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 504667 secF 1036099 secF Escherichia coli CFT073 preprotein translocase subunit SecF NP_752453.2 503696 D 199310 CDS NP_752454.1 26246415 1036095 504728..505144 1 NC_004431.1 Escherichia coli K-12 ortholog: b0410; Escherichia coli O157:H7 ortholog: z0511; hypothetical protein 505144 yajD 1036095 yajD Escherichia coli CFT073 hypothetical protein NP_752454.1 504728 D 199310 CDS NP_752455.1 26246416 1036105 complement(505182..506114) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512; nucleoside-specific channel-forming protein tsx 506114 tsx 1036105 tsx Escherichia coli CFT073 nucleoside-specific channel-forming protein tsx NP_752455.1 505182 R 199310 CDS NP_752456.2 161486296 1036097 complement(506365..506904) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0412; Escherichia coli O157:H7 ortholog: z0513; hypothetical protein 506904 yajI 1036097 yajI Escherichia coli CFT073 hypothetical protein NP_752456.2 506365 R 199310 CDS NP_752457.1 26246418 1036096 507055..507504 1 NC_004431.1 Escherichia coli K-12 ortholog: b0413; Escherichia coli O157:H7 ortholog: z0514; transcriptional regulator NrdR 507504 nrdR 1036096 nrdR Escherichia coli CFT073 transcriptional regulator NrdR NP_752457.1 507055 D 199310 CDS NP_752458.1 26246419 1036098 507508..508611 1 NC_004431.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 508611 ribD 1036098 ribD Escherichia coli CFT073 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase NP_752458.1 507508 D 199310 CDS NP_752459.2 161486295 1036104 508700..509170 1 NC_004431.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 509170 ribH 1036104 ribH Escherichia coli CFT073 6,7-dimethyl-8-ribityllumazine synthase NP_752459.2 508700 D 199310 CDS NP_752460.1 26246421 1036090 complement(509160..509693) 1 NC_004431.1 hypothetical protein 509693 1036090 c0526 Escherichia coli CFT073 hypothetical protein NP_752460.1 509160 R 199310 CDS NP_752461.1 26246422 1036082 509190..509609 1 NC_004431.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 509609 nusB 1036082 nusB Escherichia coli CFT073 transcription antitermination protein NusB NP_752461.1 509190 D 199310 CDS NP_752462.1 26246423 1036092 509687..510664 1 NC_004431.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 510664 thiL 1036092 thiL Escherichia coli CFT073 thiamine monophosphate kinase NP_752462.1 509687 D 199310 CDS NP_752463.1 26246424 1036086 510642..511160 1 NC_004431.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 511160 pgpA 1036086 pgpA Escherichia coli CFT073 phosphatidylglycerophosphatase A NP_752463.1 510642 D 199310 CDS NP_752464.1 26246425 1036083 complement(511214..512188) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0419; Escherichia coli O157:H7 ortholog: z0522; oxidoreductase yajO 512188 yajO 1036083 yajO Escherichia coli CFT073 oxidoreductase yajO NP_752464.1 511214 R 199310 CDS NP_752465.1 26246426 1036087 complement(512243..514105) 1 NC_004431.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 514105 dxs 1036087 dxs Escherichia coli CFT073 1-deoxy-D-xylulose-5-phosphate synthase NP_752465.1 512243 R 199310 CDS NP_752466.1 26246427 1036084 complement(514130..515029) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0421; Escherichia coli O157:H7 ortholog: z0524; geranyltranstransferase 515029 ispA 1036084 ispA Escherichia coli CFT073 geranyltranstransferase NP_752466.1 514130 R 199310 CDS NP_752467.1 26246428 1036089 complement(515029..515271) 1 NC_004431.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 515271 xseB 1036089 xseB Escherichia coli CFT073 exodeoxyribonuclease VII small subunit NP_752467.1 515029 R 199310 CDS NP_752468.1 26246429 1036077 515477..516925 1 NC_004431.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 516925 yajK 1036077 yajK Escherichia coli CFT073 thiamine biosynthesis protein ThiI NP_752468.1 515477 D 199310 CDS NP_752469.1 26246430 1036080 complement(516979..517575) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0424; Escherichia coli O157:H7 ortholog: z0527; DJ-1 family protein 517575 thiJ 1036080 thiJ Escherichia coli CFT073 DJ-1 family protein NP_752469.1 516979 R 199310 CDS NP_752470.1 26246431 1036079 complement(517532..518443) 1 NC_004431.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 518443 apbA 1036079 apbA Escherichia coli CFT073 2-dehydropantoate 2-reductase NP_752470.1 517532 R 199310 CDS NP_752471.2 161486294 1036078 518611..519102 1 NC_004431.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 519102 yajQ 1036078 yajQ Escherichia coli CFT073 nucleotide-binding protein NP_752471.2 518611 D 199310 CDS NP_752472.1 26246433 1036067 complement(519230..520792) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0427; Escherichia coli O157:H7 ortholog: z0530; transport protein YajR 520792 yajR 1036067 yajR Escherichia coli CFT073 transport protein YajR NP_752472.1 519230 R 199310 CDS NP_752473.1 26246434 1036068 complement(520743..521633) 1 NC_004431.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 521633 cyoE 1036068 cyoE Escherichia coli CFT073 protoheme IX farnesyltransferase NP_752473.1 520743 R 199310 CDS NP_752474.1 26246435 1036076 complement(521645..521974) 1 NC_004431.1 Ubiquinol oxidase chain D; Escherichia coli K-12 ortholog: b0429; Escherichia coli O157:H7 ortholog: z0532; cytochrome o ubiquinol oxidase subunit IV 521974 cyoD 1036076 cyoD Escherichia coli CFT073 cytochrome o ubiquinol oxidase subunit IV NP_752474.1 521645 R 199310 CDS NP_752475.1 26246436 1036073 complement(521974..522588) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0430; Escherichia coli O157:H7 ortholog: z0533; cytochrome o ubiquinol oxidase subunit III 522588 cyoC 1036073 cyoC Escherichia coli CFT073 cytochrome o ubiquinol oxidase subunit III NP_752475.1 521974 R 199310 CDS NP_752476.1 26246437 1036065 complement(522578..524569) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0431; Escherichia coli O157:H7 ortholog: z0534; cytochrome o ubiquinol oxidase subunit I 524569 cyoB 1036065 cyoB Escherichia coli CFT073 cytochrome o ubiquinol oxidase subunit I NP_752476.1 522578 R 199310 CDS NP_752477.1 26246438 1036056 complement(524591..525538) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0432; Escherichia coli O157:H7 ortholog: z0535; cytochrome o ubiquinol oxidase subunit II 525538 cyoA 1036056 cyoA Escherichia coli CFT073 cytochrome o ubiquinol oxidase subunit II NP_752477.1 524591 R 199310 CDS NP_752478.1 26246439 1036062 complement(525997..527472) 1 NC_004431.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 527472 ampG 1036062 ampG Escherichia coli CFT073 muropeptide transporter NP_752478.1 525997 R 199310 CDS NP_752479.1 26246440 1036063 527471..528070 1 NC_004431.1 hypothetical protein 528070 1036063 c0545 Escherichia coli CFT073 hypothetical protein NP_752479.1 527471 D 199310 CDS NP_752480.2 161486293 1038095 complement(527516..528094) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0434; Escherichia coli O157:H7 ortholog: z0537; hypothetical protein 528094 yajG 1038095 yajG Escherichia coli CFT073 hypothetical protein NP_752480.2 527516 R 199310 CDS NP_752481.1 26246442 1035864 complement(528144..528275) 1 NC_004431.1 hypothetical protein 528275 1035864 c0547 Escherichia coli CFT073 hypothetical protein NP_752481.1 528144 R 199310 CDS NP_752482.2 161486292 1038029 528399..528716 1 NC_004431.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 528716 bolA 1038029 bolA Escherichia coli CFT073 transcriptional regulator BolA NP_752482.2 528399 D 199310 CDS NP_752483.1 26246444 1036060 complement(528643..529065) 1 NC_004431.1 hypothetical protein 529065 1036060 c0549 Escherichia coli CFT073 hypothetical protein NP_752483.1 528643 R 199310 CDS NP_752484.1 26246445 1035216 528725..528913 1 NC_004431.1 hypothetical protein 528913 1035216 c0550 Escherichia coli CFT073 hypothetical protein NP_752484.1 528725 D 199310 CDS NP_752485.1 26246446 1035172 529060..530358 1 NC_004431.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 530358 tig 1035172 tig Escherichia coli CFT073 trigger factor NP_752485.1 529060 D 199310 CDS NP_752486.1 26246447 1035161 complement(529069..530370) 1 NC_004431.1 hypothetical protein 530370 1035161 c0552 Escherichia coli CFT073 hypothetical protein NP_752486.1 529069 R 199310 CDS NP_752487.1 26246448 1035224 530604..531227 1 NC_004431.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 531227 clpP 1035224 clpP Escherichia coli CFT073 ATP-dependent Clp protease proteolytic subunit NP_752487.1 530604 D 199310 CDS NP_752488.1 26246449 1039027 531353..532627 1 NC_004431.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 532627 clpX 1039027 clpX Escherichia coli CFT073 ATP-dependent protease ATP-binding subunit ClpX NP_752488.1 531353 D 199310 CDS NP_752489.1 26246450 1035203 532770..535169 1 NC_004431.1 Escherichia coli K-12 ortholog: b0439; Escherichia coli O157:H7 ortholog: z0545; DNA-binding ATP-dependent protease La 535169 lon 1035203 lon Escherichia coli CFT073 DNA-binding ATP-dependent protease La NP_752489.1 532770 D 199310 CDS NP_752490.1 26246451 1035227 535378..535650 1 NC_004431.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 535650 hupB 1035227 hupB Escherichia coli CFT073 transcriptional regulator HU subunit beta NP_752490.1 535378 D 199310 CDS NP_752491.1 26246452 1040432 535842..537713 1 NC_004431.1 Escherichia coli K-12 ortholog: b0441; Escherichia coli O157:H7 ortholog: z0548; peptidyl-prolyl cis-trans isomerase (rotamase D) 537713 ybaU 1040432 ybaU Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase (rotamase D) NP_752491.1 535842 D 199310 CDS NP_752492.1 26246453 1035219 537864..538235 1 NC_004431.1 Escherichia coli K-12 ortholog: b0442; Escherichia coli O157:H7 ortholog: z0549; hypothetical protein 538235 ybaV 1035219 ybaV Escherichia coli CFT073 hypothetical protein NP_752492.1 537864 D 199310 CDS NP_752493.1 26246454 1036609 538341..538739 1 NC_004431.1 Escherichia coli K-12 ortholog: b0443; Escherichia coli O157:H7 ortholog: z0550; hypothetical protein 538739 ybaW 1036609 ybaW Escherichia coli CFT073 hypothetical protein NP_752493.1 538341 D 199310 CDS NP_752494.1 26246455 1035089 complement(538791..539486) 1 NC_004431.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 539486 ybaX 1035089 ybaX Escherichia coli CFT073 queuosine biosynthesis protein QueC NP_752494.1 538791 R 199310 CDS NP_752495.1 26246456 1035106 complement(539551..541266) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0445; Escherichia coli O157:H7 ortholog: z0552; hypothetical protein 541266 ybaE 1035106 ybaE Escherichia coli CFT073 hypothetical protein NP_752495.1 539551 R 199310 CDS NP_752496.1 26246457 1035143 541339..542169 1 NC_004431.1 Escherichia coli K-12 ortholog: b0446; Escherichia coli O157:H7 ortholog: z0553; Cof protein 542169 cof 1035143 cof Escherichia coli CFT073 Cof protein NP_752496.1 541339 D 199310 CDS NP_752497.1 26246458 1035736 542302..542811 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 542811 1035736 c0563 Escherichia coli CFT073 hypothetical protein NP_752497.1 542302 D 199310 CDS NP_752498.1 26246459 1034928 542925..543491 1 NC_004431.1 Escherichia coli K-12 ortholog: b0447; Escherichia coli O157:H7 ortholog: z0555; transcriptional regulator YbaO 543491 ybaO 1034928 ybaO Escherichia coli CFT073 transcriptional regulator YbaO NP_752498.1 542925 D 199310 CDS NP_752499.1 26246460 1040487 543521..545293 1 NC_004431.1 Escherichia coli K-12 ortholog: b0448; Escherichia coli O157:H7 ortholog: z0557; multidrug transporter membrane\ATP-binding components 545293 mdlA 1040487 mdlA Escherichia coli CFT073 multidrug transporter membrane\ATP-binding components NP_752499.1 543521 D 199310 CDS NP_752500.2 229106386 1040474 545286..547067 1 NC_004431.1 Escherichia coli K-12 ortholog: b0449; Escherichia coli O157:H7 ortholog: z0559; multidrug transporter membrane\ATP-binding components 547067 mdlB 1040474 mdlB Escherichia coli CFT073 multidrug transporter membrane\ATP-binding components NP_752500.2 545286 D 199310 CDS NP_752501.1 26246462 1034985 complement(547081..547221) 1 NC_004431.1 hypothetical protein 547221 1034985 c0567 Escherichia coli CFT073 hypothetical protein NP_752501.1 547081 R 199310 CDS NP_752502.1 26246463 1036790 547248..547586 1 NC_004431.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 547586 glnK 1036790 glnK Escherichia coli CFT073 nitrogen regulatory protein P-II 2 NP_752502.1 547248 D 199310 CDS NP_752503.1 26246464 1040469 complement(547305..547538) 1 NC_004431.1 hypothetical protein 547538 1040469 c0569 Escherichia coli CFT073 hypothetical protein NP_752503.1 547305 R 199310 CDS NP_752504.1 26246465 1035428 547616..548902 1 NC_004431.1 Escherichia coli K-12 ortholog: b0451; Escherichia coli O157:H7 ortholog: z0563; ammonium transporter 548902 amtB 1035428 amtB Escherichia coli CFT073 ammonium transporter NP_752504.1 547616 D 199310 CDS NP_752505.1 26246466 1040477 complement(548951..549895) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0452; Escherichia coli O157:H7 ortholog: z0564; acyl-CoA thioesterase 549895 tesB 1040477 tesB Escherichia coli CFT073 acyl-CoA thioesterase NP_752505.1 548951 R 199310 CDS NP_752506.1 26246467 1040420 550029..550601 1 NC_004431.1 Escherichia coli K-12 ortholog: b0453; Escherichia coli O157:H7 ortholog: z0565; hypothetical protein 550601 ybaY 1040420 ybaY Escherichia coli CFT073 hypothetical protein NP_752506.1 550029 D 199310 CDS NP_752507.1 26246468 1039941 complement(550632..551042) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0454; Escherichia coli O157:H7 ortholog: z0566; hypothetical protein 551042 ybaZ 1039941 ybaZ Escherichia coli CFT073 hypothetical protein NP_752507.1 550632 R 199310 CDS NP_752508.1 26246469 1035401 551322..551675 1 NC_004431.1 Escherichia coli K-12 ortholog: b0456; Escherichia coli O157:H7 ortholog: z0568; hypothetical protein 551675 ybaA 1035401 ybaA Escherichia coli CFT073 hypothetical protein NP_752508.1 551322 D 199310 CDS NP_752509.1 26246470 1036619 complement(551717..553273) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0457; Escherichia coli O157:H7 ortholog: z0569; hypothetical protein 553273 ylaB 1036619 ylaB Escherichia coli CFT073 hypothetical protein NP_752509.1 551717 R 199310 CDS NP_752510.1 26246471 1040489 complement(553431..553940) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0458; Escherichia coli O157:H7 ortholog: z0570; hypothetical protein 553940 ylaC 1040489 ylaC Escherichia coli CFT073 hypothetical protein NP_752510.1 553431 R 199310 CDS NP_752511.1 26246472 1035420 complement(554017..554568) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0459; Escherichia coli O157:H7 ortholog: z0571; maltose O-acetyltransferase 554568 ylaD 1035420 ylaD Escherichia coli CFT073 maltose O-acetyltransferase NP_752511.1 554017 R 199310 CDS NP_752512.1 26246473 1035413 complement(554741..554971) 1 NC_004431.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 554971 hha 1035413 hha Escherichia coli CFT073 hemolysin expression-modulating protein NP_752512.1 554741 R 199310 CDS NP_752513.1 26246474 1039693 complement(554985..555359) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0461; Escherichia coli O157:H7 ortholog: z0574; hypothetical protein 555359 ybaJ 1039693 ybaJ Escherichia coli CFT073 hypothetical protein NP_752513.1 554985 R 199310 CDS NP_752514.1 26246475 1035438 complement(555904..559053) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0462; Escherichia coli O157:H7 ortholog: z0576; acriflavin resistance protein B 559053 acrB 1035438 acrB Escherichia coli CFT073 acriflavin resistance protein B NP_752514.1 555904 R 199310 CDS NP_752515.1 26246476 1035417 complement(559076..560305) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z0578; acriflavin resistance protein A 560305 acrA 1035417 acrA Escherichia coli CFT073 acriflavin resistance protein A NP_752515.1 559076 R 199310 CDS NP_752516.1 26246477 1035995 560411..561058 1 NC_004431.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 561058 acrR 1035995 acrR Escherichia coli CFT073 DNA-binding transcriptional repressor AcrR NP_752516.1 560411 D 199310 CDS NP_752517.1 26246478 1035541 561140..561304 1 NC_004431.1 hypothetical protein 561304 1035541 c0583 Escherichia coli CFT073 hypothetical protein NP_752517.1 561140 D 199310 CDS NP_752518.1 26246479 1035456 561186..564548 1 NC_004431.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 564548 aefA 1035456 aefA Escherichia coli CFT073 potassium efflux protein KefA NP_752518.1 561186 D 199310 CDS NP_752519.1 26246480 1035545 complement(564760..564921) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0466; Escherichia coli O157:H7 ortholog: z0583; hypothetical protein 564921 ybaM 1035545 ybaM Escherichia coli CFT073 hypothetical protein NP_752519.1 564760 R 199310 CDS NP_752520.1 26246481 1035924 complement(564935..565462) 1 NC_004431.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 565462 priC 1035924 priC Escherichia coli CFT073 primosomal replication protein N'' NP_752520.1 564935 R 199310 CDS NP_752521.1 26246482 1035989 565532..565909 1 NC_004431.1 Escherichia coli K-12 ortholog: b0468; Escherichia coli O157:H7 ortholog: z0585; hypothetical protein 565909 ybaN 1035989 ybaN Escherichia coli CFT073 hypothetical protein NP_752521.1 565532 D 199310 CDS NP_752522.1 26246483 1037590 566008..566613 1 NC_004431.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 566613 apt 1037590 apt Escherichia coli CFT073 adenine phosphoribosyltransferase NP_752522.1 566008 D 199310 CDS NP_752523.1 26246484 1036055 566742..568673 1 NC_004431.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 568673 dnaX 1036055 dnaX Escherichia coli CFT073 DNA polymerase III subunits gamma and tau NP_752523.1 566742 D 199310 CDS NP_752524.1 26246485 1036011 complement(568702..569079) 1 NC_004431.1 Residues 1 to 125 of 125 are 99.19 pct identical to residues 1 to 125 of 125 from GenPept.129 : >gb|AAB40225.1| (U82664) hypothetical protein [Escherichia coli]; hypothetical protein 569079 1036011 c0590 Escherichia coli CFT073 hypothetical protein NP_752524.1 568702 R 199310 CDS NP_752525.1 26246486 1037598 568711..569055 1 NC_004431.1 Escherichia coli K-12 ortholog: b0471; Escherichia coli O157:H7 ortholog: z0588; hypothetical protein 569055 ybaB 1037598 ybaB Escherichia coli CFT073 hypothetical protein NP_752525.1 568711 D 199310 CDS NP_752526.1 26246487 1036101 569055..569660 1 NC_004431.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 569660 recR 1036101 recR Escherichia coli CFT073 recombination protein RecR NP_752526.1 569055 D 199310 CDS NP_752527.1 26246488 1037575 569770..571644 1 NC_004431.1 molecular chaperone; heat shock protein 90 571644 htpG 1037575 htpG Escherichia coli CFT073 heat shock protein 90 NP_752527.1 569770 D 199310 CDS NP_752528.2 161486291 1035723 571825..572469 1 NC_004431.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 572469 adk 1035723 adk Escherichia coli CFT073 adenylate kinase NP_752528.2 571825 D 199310 CDS NP_752529.1 26246490 1036165 572601..573563 1 NC_004431.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 573563 hemH 1036165 hemH Escherichia coli CFT073 ferrochelatase NP_752529.1 572601 D 199310 CDS NP_752530.1 26246491 1035679 complement(573560..574519) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0476; Escherichia coli O157:H7 ortholog: z0593; acetyl esterase 574519 ybaC 1035679 ybaC Escherichia coli CFT073 acetyl esterase NP_752530.1 573560 R 199310 CDS NP_752531.1 26246492 1036004 574671..575975 1 NC_004431.1 Escherichia coli K-12 ortholog: b0477; Escherichia coli O157:H7 ortholog: z0596; inosine-guanosine kinase 575975 gsk 1036004 gsk Escherichia coli CFT073 inosine-guanosine kinase NP_752531.1 574671 D 199310 CDS NP_752532.1 26246493 1038193 complement(576105..577781) 1 NC_004431.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 577781 ybaL 1038193 ybaL Escherichia coli CFT073 cation:proton antiport protein NP_752532.1 576105 R 199310 CDS NP_752533.1 26246494 1040025 complement(578019..579239) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0479; Escherichia coli O157:H7 ortholog: z0598; fosmidomycin resistance protein 579239 fsr 1040025 fsr Escherichia coli CFT073 fosmidomycin resistance protein NP_752533.1 578019 R 199310 CDS NP_752534.1 26246495 1038205 579457..581109 1 NC_004431.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 581109 ushA 1038205 ushA Escherichia coli CFT073 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic NP_752534.1 579457 D 199310 CDS NP_752535.1 26246496 1036840 complement(581146..581625) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0481; Escherichia coli O157:H7 ortholog: z0600; hypothetical protein 581625 ybaK 1036840 ybaK Escherichia coli CFT073 hypothetical protein NP_752535.1 581146 R 199310 CDS NP_752536.1 26246497 1036237 complement(581829..582623) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0482; Escherichia coli O157:H7 ortholog: z0601; hypothetical protein 582623 ybaP 1036237 ybaP Escherichia coli CFT073 hypothetical protein NP_752536.1 581829 R 199310 CDS NP_752537.1 26246498 1035360 583093..583434 1 NC_004431.1 Escherichia coli K-12 ortholog: b0483; Escherichia coli O157:H7 ortholog: z0602; hypothetical protein 583434 ybaQ 1035360 ybaQ Escherichia coli CFT073 hypothetical protein NP_752537.1 583093 D 199310 CDS NP_752538.1 26246499 1036268 complement(583492..585996) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0484; Escherichia coli O157:H7 ortholog: z0604; copper exporting ATPase 585996 copA 1036268 copA Escherichia coli CFT073 copper exporting ATPase NP_752538.1 583492 R 199310 CDS NP_752539.1 26246500 1036278 586259..587191 1 NC_004431.1 catalyzes the formation of glutamate from glutamine; glutaminase 587191 ybaS 1036278 ybaS Escherichia coli CFT073 glutaminase NP_752539.1 586259 D 199310 CDS NP_752540.1 26246501 1039634 587194..588486 1 NC_004431.1 Escherichia coli K-12 ortholog: b0486; Escherichia coli O157:H7 ortholog: z0607; transport protein YbaT 588486 ybaT 1039634 ybaT Escherichia coli CFT073 transport protein YbaT NP_752540.1 587194 D 199310 CDS NP_752541.1 26246502 1038258 588611..589018 1 NC_004431.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 589018 ybbI 1038258 ybbI Escherichia coli CFT073 DNA-binding transcriptional regulator CueR NP_752541.1 588611 D 199310 CDS NP_752542.1 26246503 1036444 complement(589019..590242) 1 NC_004431.1 Residues 1 to 406 of 407 are 55.58 pct identical to residues 1 to 411 of 412 from GenPept.129 : >gb|AAL19611.1| (AE008726) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 590242 1036444 c0608 Escherichia coli CFT073 hypothetical protein NP_752542.1 589019 R 199310 CDS NP_752543.1 26246504 1036276 complement(590361..590819) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0488; Escherichia coli O157:H7 ortholog: z0641; hypothetical protein 590819 ybbJ 1036276 ybbJ Escherichia coli CFT073 hypothetical protein NP_752543.1 590361 R 199310 CDS NP_752544.1 26246505 1040282 complement(590816..591733) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0489; Escherichia coli O157:H7 ortholog: z0642; hypothetical protein 591733 ybbK 1040282 ybbK Escherichia coli CFT073 hypothetical protein NP_752544.1 590816 R 199310 CDS NP_752545.1 26246506 1035919 591876..592556 1 NC_004431.1 Escherichia coli K-12 ortholog: b0490; Escherichia coli O157:H7 ortholog: z0643; ABC transporter ATP-binding protein YbbL 592556 ybbL 1035919 ybbL Escherichia coli CFT073 ABC transporter ATP-binding protein YbbL NP_752545.1 591876 D 199310 CDS NP_752546.1 26246507 1040455 complement(593386..594276) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0492; Escherichia coli O157:H7 ortholog: z0645; hypothetical protein 594276 ybbN 1040455 ybbN Escherichia coli CFT073 hypothetical protein NP_752546.1 593386 R 199310 CDS NP_752547.1 26246508 1036368 complement(594301..595110) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0493; Escherichia coli O157:H7 ortholog: z0646; short chain dehydrogenase 595110 ybbO 1036368 ybbO Escherichia coli CFT073 short chain dehydrogenase NP_752547.1 594301 R 199310 CDS NP_752548.1 26246509 1036492 complement(595100..595756) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0494; Escherichia coli O157:H7 ortholog: z0647; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 595756 tesA 1036492 tesA Escherichia coli CFT073 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 NP_752548.1 595100 R 199310 CDS NP_752549.1 26246510 1039534 595694..596380 1 NC_004431.1 Escherichia coli K-12 ortholog: b0495; Escherichia coli O157:H7 ortholog: z0648; ABC transporter ATP-binding protein YbbA 596380 ybbA 1039534 ybbA Escherichia coli CFT073 ABC transporter ATP-binding protein YbbA NP_752549.1 595694 D 199310 CDS NP_752550.1 26246511 1036171 596377..598791 1 NC_004431.1 Escherichia coli K-12 ortholog: b0496; Escherichia coli O157:H7 ortholog: z0649; hypothetical protein 598791 ybbP 1036171 ybbP Escherichia coli CFT073 hypothetical protein NP_752550.1 596377 D 199310 CDS NP_752551.1 26246512 1036042 complement(598942..599901) 1 NC_004431.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 599901 ybbB 1036042 ybbB Escherichia coli CFT073 tRNA 2-selenouridine synthase NP_752551.1 598942 R 199310 CDS NP_752552.1 26246513 1039678 complement(600096..601022) 1 NC_004431.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 601022 ybbS 1039678 ybbS Escherichia coli CFT073 DNA-binding transcriptional activator AllS NP_752552.1 600096 R 199310 CDS NP_752553.1 26246514 1036248 601252..601734 1 NC_004431.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 601734 ybbT 1036248 ybbT Escherichia coli CFT073 ureidoglycolate hydrolase NP_752553.1 601252 D 199310 CDS NP_752554.1 26246515 1036274 601812..602627 1 NC_004431.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 602627 ybbU 1036274 ybbU Escherichia coli CFT073 DNA-binding transcriptional repressor AllR NP_752554.1 601812 D 199310 CDS NP_752555.2 161486290 1036035 602717..604498 1 NC_004431.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 604498 gcl 1036035 gcl Escherichia coli CFT073 glyoxylate carboligase NP_752555.2 602717 D 199310 CDS NP_752556.1 26246517 1036160 604511..605287 1 NC_004431.1 Escherichia coli K-12 ortholog: b0508; Escherichia coli O157:H7 ortholog: z0662; hydroxypyruvate isomerase 605287 gip 1036160 gip Escherichia coli CFT073 hydroxypyruvate isomerase NP_752556.1 604511 D 199310 CDS NP_752557.1 26246518 1036046 605387..606265 1 NC_004431.1 Escherichia coli K-12 ortholog: b0509; Escherichia coli O157:H7 ortholog: z0663; 2-hydroxy-3-oxopropionate reductase 606265 ybbQ 1036046 ybbQ Escherichia coli CFT073 2-hydroxy-3-oxopropionate reductase NP_752557.1 605387 D 199310 CDS NP_752558.1 26246519 1036050 606435..607889 1 NC_004431.1 Allantoin transport protein; Escherichia coli K-12 ortholog: b0511; Escherichia coli O157:H7 ortholog: z0665; allantoin permease 607889 ybbW 1036050 ybbW Escherichia coli CFT073 allantoin permease NP_752558.1 606435 D 199310 CDS NP_752559.1 26246520 1036012 607949..609310 1 NC_004431.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 609310 ybbX 1036012 ybbX Escherichia coli CFT073 allantoinase NP_752559.1 607949 D 199310 CDS NP_752560.1 26246521 1036037 609360..610667 1 NC_004431.1 Escherichia coli K-12 ortholog: b0513; Escherichia coli O157:H7 ortholog: z0668; purine permease YbbY 610667 ybbY 1036037 ybbY Escherichia coli CFT073 purine permease YbbY NP_752560.1 609360 D 199310 CDS NP_752561.1 26246522 1036043 610683..611834 1 NC_004431.1 Escherichia coli K-12 ortholog: b0514; Escherichia coli O157:H7 ortholog: z0669; glycerate kinase II 611834 ybbZ 1036043 ybbZ Escherichia coli CFT073 glycerate kinase II NP_752561.1 610683 D 199310 CDS NP_752562.1 26246523 1036034 complement(611963..612748) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0515; Escherichia coli O157:H7 ortholog: z0670; hypothetical protein 612748 ylbA 1036034 ylbA Escherichia coli CFT073 hypothetical protein NP_752562.1 611963 R 199310 CDS NP_752563.1 26246524 1035999 complement(612759..614012) 1 NC_004431.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 614012 ylbB 1035999 ylbB Escherichia coli CFT073 allantoate amidohydrolase NP_752563.1 612759 R 199310 CDS NP_752564.1 26246525 1036000 complement(614016..615065) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0517; Escherichia coli O157:H7 ortholog: z0672; ureidoglycolate dehydrogenase 615065 1036000 c0631 Escherichia coli CFT073 ureidoglycolate dehydrogenase NP_752564.1 614016 R 199310 CDS NP_752565.1 26246526 1036020 615382..617049 1 NC_004431.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 617049 fdrA 1036020 fdrA Escherichia coli CFT073 membrane protein FdrA NP_752565.1 615382 D 199310 CDS NP_752566.1 26246527 1036010 617059..618318 1 NC_004431.1 Escherichia coli K-12 ortholog: b0519; Escherichia coli O157:H7 ortholog: z0674; hypothetical protein 618318 ylbE 1036010 ylbE Escherichia coli CFT073 hypothetical protein NP_752566.1 617059 D 199310 CDS NP_752567.1 26246528 1039644 618236..619144 1 NC_004431.1 Escherichia coli K-12 ortholog: b0520; Escherichia coli O157:H7 ortholog: z0675; hypothetical protein 619144 ylbF 1039644 ylbF Escherichia coli CFT073 hypothetical protein NP_752567.1 618236 D 199310 CDS NP_752568.1 26246529 1035993 619141..620034 1 NC_004431.1 forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate; carbamate kinase 620034 arcC 1035993 arcC Escherichia coli CFT073 carbamate kinase NP_752568.1 619141 D 199310 CDS NP_752569.1 26246530 1035093 complement(620167..621234) 1 NC_004431.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 621234 purK 1035093 purK Escherichia coli CFT073 phosphoribosylaminoimidazole carboxylase ATPase subunit NP_752569.1 620167 R 199310 CDS NP_752570.1 26246531 1040159 complement(621231..621767) 1 NC_004431.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit 621767 purE 1040159 purE Escherichia coli CFT073 phosphoribosylaminoimidazole carboxylase catalytic subunit NP_752570.1 621231 R 199310 CDS NP_752571.1 26246532 1035965 complement(621836..622165) 1 NC_004431.1 hypothetical protein 622165 1035965 c0638 Escherichia coli CFT073 hypothetical protein NP_752571.1 621836 R 199310 CDS NP_752572.1 26246533 1035968 complement(622276..622998) 1 NC_004431.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 622998 ybbF 1035968 ybbF Escherichia coli CFT073 UDP-2,3-diacylglucosamine hydrolase NP_752572.1 622276 R 199310 CDS NP_752573.1 26246534 1035362 622989..623675 1 NC_004431.1 Residues 1 to 228 of 228 are 96.49 pct identical to residues 1 to 228 of 228 from GenPept.129 : >gb|AAB40278.1| (U82664) hypothetical protein [Escherichia coli]; hypothetical protein 623675 1035362 c0640 Escherichia coli CFT073 hypothetical protein NP_752573.1 622989 D 199310 CDS NP_752574.1 26246535 1038645 complement(623001..623495) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0525; Escherichia coli O157:H7 ortholog: z0680; peptidyl-prolyl cis-trans isomerase B (rotamase B) 623495 ppiB 1038645 ppiB Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase B (rotamase B) NP_752574.1 623001 R 199310 CDS NP_752575.1 26246536 1040498 623669..625054 1 NC_004431.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 625054 cysS 1040498 cysS Escherichia coli CFT073 cysteinyl-tRNA synthetase NP_752575.1 623669 D 199310 CDS NP_752576.1 26246537 1035966 complement(625090..625527) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0527; Escherichia coli O157:H7 ortholog: z0682; hypothetical protein 625527 ybcI 1035966 ybcI Escherichia coli CFT073 hypothetical protein NP_752576.1 625090 R 199310 CDS NP_752577.2 161486289 1035957 complement(625720..625932) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0528; Escherichia coli O157:H7 ortholog: z0683; hypothetical protein 625932 ybcJ 1035957 ybcJ Escherichia coli CFT073 hypothetical protein NP_752577.2 625720 R 199310 CDS NP_752578.1 26246539 1035902 complement(625934..626800) 1 NC_004431.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 626800 folD 1035902 folD Escherichia coli CFT073 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_752578.1 625934 R 199310 CDS NP_752579.1 26246540 1038490 626841..627038 1 NC_004431.1 hypothetical protein 627038 1038490 c0646 Escherichia coli CFT073 hypothetical protein NP_752579.1 626841 D 199310 CDS NP_752580.1 26246541 1035946 627789..628145 1 NC_004431.1 Escherichia coli K-12 ortholog: b1546; Escherichia coli O157:H7 ortholog: z1920; tail fiber assembly protein 628145 ydfM 1035946 ydfM Escherichia coli CFT073 tail fiber assembly protein NP_752580.1 627789 D 199310 CDS NP_752581.1 26246542 1039654 628118..628243 1 NC_004431.1 hypothetical protein 628243 1039654 c0650 Escherichia coli CFT073 hypothetical protein NP_752581.1 628118 D 199310 CDS NP_752582.1 26246543 1039676 complement(628200..628865) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0562; Escherichia coli O157:H7 ortholog: z1925; hypothetical protein 628865 1039676 c0651 Escherichia coli CFT073 hypothetical protein NP_752582.1 628200 R 199310 CDS NP_752583.1 26246544 1035234 complement(629100..630053) 1 NC_004431.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 630053 ompT 1035234 ompT Escherichia coli CFT073 outer membrane protease NP_752583.1 629100 R 199310 CDS NP_752584.1 26246545 1035298 complement(630712..631602) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0567; Escherichia coli O157:H7 ortholog: z0697; hypothetical protein 631602 ybcH 1035298 ybcH Escherichia coli CFT073 hypothetical protein NP_752584.1 630712 R 199310 CDS NP_752585.1 26246546 1040198 complement(631603..634596) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0568; Escherichia coli O157:H7 ortholog: z0698; bacteriophage N4 receptor, outer membrane subunit 634596 nfrA 1040198 nfrA Escherichia coli CFT073 bacteriophage N4 receptor, outer membrane subunit NP_752585.1 631603 R 199310 CDS NP_752586.1 26246547 1035290 complement(634562..636724) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0569; Escherichia coli O157:H7 ortholog: z0699; bacteriophage N4 adsorption protein B 636724 nfrB 1035290 nfrB Escherichia coli CFT073 bacteriophage N4 adsorption protein B NP_752586.1 634562 R 199310 CDS NP_752587.1 26246548 1039642 complement(636949..638391) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0570; Escherichia coli O157:H7 ortholog: z0708; sensor kinase CusS 638391 cusS 1039642 cusS Escherichia coli CFT073 sensor kinase CusS NP_752587.1 636949 R 199310 CDS NP_752588.1 26246549 1036802 complement(638381..639064) 1 NC_004431.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 639064 cusR 1036802 cusR Escherichia coli CFT073 DNA-binding transcriptional activator CusR NP_752588.1 638381 R 199310 CDS NP_752589.1 26246550 1040042 639221..640603 1 NC_004431.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 640603 cusC 1040042 cusC Escherichia coli CFT073 copper/silver efflux system outer membrane protein CusC NP_752589.1 639221 D 199310 CDS NP_752590.1 26246551 1035280 640627..640959 1 NC_004431.1 Escherichia coli K-12 ortholog: b0573; Escherichia coli O157:H7 ortholog: z0712; periplasmic copper-binding protein 640959 cusX 1035280 cusX Escherichia coli CFT073 periplasmic copper-binding protein NP_752590.1 640627 D 199310 CDS NP_752591.1 26246552 1039714 640975..642198 1 NC_004431.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 642198 cusB 1039714 cusB Escherichia coli CFT073 copper/silver efflux system membrane fusion protein CusB NP_752591.1 640975 D 199310 CDS NP_752592.1 26246553 1035331 642210..645353 1 NC_004431.1 Escherichia coli K-12 ortholog: b0575; Escherichia coli O157:H7 ortholog: z0714; cation efflux system protein cusA 645353 cusA 1035331 cusA Escherichia coli CFT073 cation efflux system protein cusA NP_752592.1 642210 D 199310 CDS NP_752593.1 26246554 1040425 645419..646837 1 NC_004431.1 Escherichia coli K-12 ortholog: b0576; Escherichia coli O157:H7 ortholog: z0715; phenylalanine transporter 646837 pheP 1040425 pheP Escherichia coli CFT073 phenylalanine transporter NP_752593.1 645419 D 199310 CDS NP_752594.1 26246555 1035315 complement(646994..648241) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0577; Escherichia coli O157:H7 ortholog: z0716; hypothetical protein 648241 ybdG 1035315 ybdG Escherichia coli CFT073 hypothetical protein NP_752594.1 646994 R 199310 CDS NP_752595.1 26246556 1035082 complement(648349..649002) 1 NC_004431.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 649002 nfnB 1035082 nfnB Escherichia coli CFT073 dihydropteridine reductase NP_752595.1 648349 R 199310 CDS NP_752596.1 26246557 1035655 complement(649081..649464) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0579; Escherichia coli O157:H7 ortholog: z0718; hypothetical protein 649464 ybdF 1035655 ybdF Escherichia coli CFT073 hypothetical protein NP_752596.1 649081 R 199310 CDS NP_752597.1 26246558 1034951 complement(649529..649777) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0580; Escherichia coli O157:H7 ortholog: z0719; hypothetical protein 649777 ybdJ 1034951 ybdJ Escherichia coli CFT073 hypothetical protein NP_752597.1 649529 R 199310 CDS NP_752598.1 26246559 1040424 complement(649843..650961) 1 NC_004431.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 650961 ybdK 1040424 ybdK Escherichia coli CFT073 carboxylate-amine ligase NP_752598.1 649843 R 199310 CDS NP_752599.1 26246560 1035265 complement(651687..652457) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0583; Escherichia coli O157:H7 ortholog: z0723; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 652457 entD 1035265 entD Escherichia coli CFT073 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex NP_752599.1 651687 R 199310 CDS NP_752600.1 26246561 1034981 complement(652482..654722) 1 NC_004431.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 654722 fepA 1034981 fepA Escherichia coli CFT073 outer membrane receptor FepA NP_752600.1 652482 R 199310 CDS NP_752601.1 26246562 1036685 654715..654846 1 NC_004431.1 hypothetical protein 654846 1036685 c0670 Escherichia coli CFT073 hypothetical protein NP_752601.1 654715 D 199310 CDS NP_752602.1 26246563 1035107 654965..656167 1 NC_004431.1 Ferric enterobactin esterase; Escherichia coli K-12 ortholog: b0585; Escherichia coli O157:H7 ortholog: z0725; enterobactin/ferric enterobactin esterase 656167 fes 1035107 fes Escherichia coli CFT073 enterobactin/ferric enterobactin esterase NP_752602.1 654965 D 199310 CDS NP_752603.3 347357900 1035415 656164..656388 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0726; hypothetical protein 656388 1035415 c0672 Escherichia coli CFT073 hypothetical protein NP_752603.3 656164 D 199310 CDS NP_752604.1 26246565 1035086 656385..660266 1 NC_004431.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 660266 entF 1035086 entF Escherichia coli CFT073 enterobactin synthase subunit F NP_752604.1 656385 D 199310 CDS NP_752605.1 26246566 1039935 660513..661646 1 NC_004431.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 661646 fepE 1039935 fepE Escherichia coli CFT073 ferric enterobactin transport protein FepE NP_752605.1 660513 D 199310 CDS NP_752606.1 26246567 1035338 complement(661643..662458) 1 NC_004431.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 662458 fepC 1035338 fepC Escherichia coli CFT073 iron-enterobactin transporter ATP-binding protein NP_752606.1 661643 R 199310 CDS NP_752607.1 26246568 1035293 complement(662455..663447) 1 NC_004431.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 663447 fepG 1035293 fepG Escherichia coli CFT073 iron-enterobactin transporter permease NP_752607.1 662455 R 199310 CDS NP_752608.1 26246569 1035286 complement(663444..664460) 1 NC_004431.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 664460 fepD 1035286 fepD Escherichia coli CFT073 iron-enterobactin transporter membrane protein NP_752608.1 663444 R 199310 CDS NP_752609.1 26246570 1035393 664559..665809 1 NC_004431.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 665809 ybdA 1035393 ybdA Escherichia coli CFT073 enterobactin exporter EntS NP_752609.1 664559 D 199310 CDS NP_752610.1 26246571 1035309 complement(665813..666769) 1 NC_004431.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 666769 fepB 1035309 fepB Escherichia coli CFT073 iron-enterobactin transporter periplasmic binding protein NP_752610.1 665813 R 199310 CDS NP_752611.1 26246572 1035606 666946..668133 1 NC_004431.1 synthesizes isochorismate acid from chorismate; isochorismate synthase 668133 entC 1035606 entC Escherichia coli CFT073 isochorismate synthase NP_752611.1 666946 D 199310 CDS NP_752612.1 26246573 1035604 668143..669753 1 NC_004431.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 669753 entE 1035604 entE Escherichia coli CFT073 enterobactin synthase subunit E NP_752612.1 668143 D 199310 CDS NP_752613.1 26246574 1035596 669767..670624 1 NC_004431.1 Escherichia coli K-12 ortholog: b0595; Escherichia coli O157:H7 ortholog: z0737; isochorismatase 670624 entB 1035596 entB Escherichia coli CFT073 isochorismatase NP_752613.1 669767 D 199310 CDS NP_752614.1 26246575 1035595 670624..671370 1 NC_004431.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 671370 entA 1035595 entA Escherichia coli CFT073 2,3-dihydroxybenzoate-2,3-dehydrogenase NP_752614.1 670624 D 199310 CDS NP_752615.1 26246576 1035608 671373..671786 1 NC_004431.1 P15; Escherichia coli K-12 ortholog: b0597; Escherichia coli O157:H7 ortholog: z0739; hypothetical protein 671786 ybdB 1035608 ybdB Escherichia coli CFT073 hypothetical protein NP_752615.1 671373 D 199310 CDS NP_752616.1 26246577 1035597 671967..674072 1 NC_004431.1 Escherichia coli K-12 ortholog: b0598; Escherichia coli O157:H7 ortholog: z0740; carbon starvation protein A 674072 cstA 1035597 cstA Escherichia coli CFT073 carbon starvation protein A NP_752616.1 671967 D 199310 CDS NP_752617.1 26246578 1035607 674185..674382 1 NC_004431.1 Escherichia coli K-12 ortholog: b4353; Escherichia coli O157:H7 ortholog: z5952; hypothetical protein 674382 1035607 c0686 Escherichia coli CFT073 hypothetical protein NP_752617.1 674185 D 199310 CDS NP_752618.1 26246579 1035610 complement(674392..675480) 1 NC_004431.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 675480 ybdH 1035610 ybdH Escherichia coli CFT073 hypothetical protein NP_752618.1 674392 R 199310 CDS NP_752619.1 26246580 1035707 675589..676749 1 NC_004431.1 catalyzes the transfer of an amino moiety; aminotransferase 676749 ybdL 1035707 ybdL Escherichia coli CFT073 aminotransferase NP_752619.1 675589 D 199310 CDS NP_752620.1 26246581 1035611 complement(676750..677379) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z0744; hypothetical protein 677379 1035611 c0689 Escherichia coli CFT073 hypothetical protein NP_752620.1 676750 R 199310 CDS NP_752621.1 26246582 1035638 complement(677352..678572) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z0746; hypothetical protein 678572 1035638 c0690 Escherichia coli CFT073 hypothetical protein NP_752621.1 677352 R 199310 CDS NP_752622.1 26246583 1035717 complement(678719..679657) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0603; Escherichia coli O157:H7 ortholog: z0747; transcriptional regulator YbdO 679657 ybdO 1035717 ybdO Escherichia coli CFT073 transcriptional regulator YbdO NP_752622.1 678719 R 199310 CDS NP_752623.3 347357899 1035712 complement(679826..680632) 1 NC_004431.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 680632 dsbG 1035712 dsbG Escherichia coli CFT073 disulfide isomerase/thiol-disulfide oxidase NP_752623.3 679826 R 199310 CDS NP_752624.1 26246585 1035746 complement(680911..681426) 1 NC_004431.1 hypothetical protein 681426 1035746 c0693 Escherichia coli CFT073 hypothetical protein NP_752624.1 680911 R 199310 CDS NP_752625.1 26246586 1035753 680944..681507 1 NC_004431.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 681507 ahpC 1035753 ahpC Escherichia coli CFT073 alkyl hydroperoxide reductase NP_752625.1 680944 D 199310 CDS NP_752626.1 26246587 1035771 681648..683243 1 NC_004431.1 Escherichia coli K-12 ortholog: b0606; Escherichia coli O157:H7 ortholog: z0750; alkyl hydroperoxide reductase 683243 ahpF 1035771 ahpF Escherichia coli CFT073 alkyl hydroperoxide reductase NP_752626.1 681648 D 199310 CDS NP_752627.1 26246588 1036875 complement(683364..683825) 1 NC_004431.1 Spots PR25/LM16/2D_000LR3; Escherichia coli K-12 ortholog: b0607; Escherichia coli O157:H7 ortholog: z0751; hypothetical protein 683825 ybdQ 1036875 ybdQ Escherichia coli CFT073 hypothetical protein NP_752627.1 683364 R 199310 CDS NP_752628.1 26246589 1035943 684077..684460 1 NC_004431.1 Escherichia coli K-12 ortholog: b0609; Escherichia coli O157:H7 ortholog: z0753; hypothetical protein 684460 1035943 c0697 Escherichia coli CFT073 hypothetical protein NP_752628.1 684077 D 199310 CDS NP_752629.1 26246590 1035714 complement(684149..684559) 1 NC_004431.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 684559 rnk 1035714 rnk Escherichia coli CFT073 nucleoside diphosphate kinase regulator NP_752629.1 684149 R 199310 CDS NP_752630.1 26246591 1036052 complement(684789..685613) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0611; Escherichia coli O157:H7 ortholog: z0755; ribonuclease I 685613 rna 1036052 rna Escherichia coli CFT073 ribonuclease I NP_752630.1 684789 R 199310 CDS NP_752631.1 26246592 1035609 complement(685709..687172) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0612; Escherichia coli O157:H7 ortholog: z0756; citrate transporter 687172 ybdS 1035609 ybdS Escherichia coli CFT073 citrate transporter NP_752631.1 685709 R 199310 CDS NP_752632.1 26246593 1040223 complement(687223..688101) 1 NC_004431.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 688101 citG 1040223 citG Escherichia coli CFT073 triphosphoribosyl-dephospho-CoA synthase NP_752632.1 687223 R 199310 CDS NP_752633.1 26246594 1036335 complement(688076..688627) 1 NC_004431.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase 688627 citX 1036335 citX Escherichia coli CFT073 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase NP_752633.1 688076 R 199310 CDS NP_752634.1 26246595 1040288 688595..689989 1 NC_004431.1 hypothetical protein 689989 1040288 c0703 Escherichia coli CFT073 hypothetical protein NP_752634.1 688595 D 199310 CDS NP_752635.1 26246596 1036665 complement(688631..690163) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0615; Escherichia coli O157:H7 ortholog: z0759; citrate lyase subunit alpha 690163 citF 1036665 citF Escherichia coli CFT073 citrate lyase subunit alpha NP_752635.1 688631 R 199310 CDS NP_752636.1 26246597 1036300 690165..691211 1 NC_004431.1 hypothetical protein 691211 1036300 c0705 Escherichia coli CFT073 hypothetical protein NP_752636.1 690165 D 199310 CDS NP_752637.1 26246598 1035930 complement(690174..691097) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0616; Escherichia coli O157:H7 ortholog: z0760; citrate lyase subunit beta 691097 citE 1035930 citE Escherichia coli CFT073 citrate lyase subunit beta NP_752637.1 690174 R 199310 CDS NP_752638.1 26246599 1036664 complement(691390..692397) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0618; Escherichia coli O157:H7 ortholog: z0762; [citrate (pro-3S)-lyase] ligase 692397 citC 1036664 citC Escherichia coli CFT073 [citrate (pro-3S)-lyase] ligase NP_752638.1 691390 R 199310 CDS NP_752639.1 26246600 1035932 692768..694486 1 NC_004431.1 Escherichia coli K-12 ortholog: b0619; Escherichia coli O157:H7 ortholog: z0764; sensor kinase dpiB 694486 citA 1035932 citA Escherichia coli CFT073 sensor kinase dpiB NP_752639.1 692768 D 199310 CDS NP_752640.1 26246601 1036713 694455..695135 1 NC_004431.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 695135 dpiA 1036713 dpiA Escherichia coli CFT073 two-component response regulator DpiA NP_752640.1 694455 D 199310 CDS NP_752641.1 26246602 1036791 complement(695176..696561) 1 NC_004431.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 696561 dcuC 1036791 dcuC Escherichia coli CFT073 C4-dicarboxylate transporter DcuC NP_752641.1 695176 R 199310 CDS NP_752642.1 26246603 1036775 697148..697708 1 NC_004431.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 697708 pagP 1036775 pagP Escherichia coli CFT073 palmitoyl transferase NP_752642.1 697148 D 199310 CDS NP_752643.2 161486286 1036735 697883..698092 1 NC_004431.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 698092 cspE 1036735 cspE Escherichia coli CFT073 cold shock protein CspE NP_752643.2 697883 D 199310 CDS NP_752645.1 26246605 1036678 complement(698146..698529) 1 NC_004431.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 698529 ccrB 1036678 ccrB Escherichia coli CFT073 camphor resistance protein CrcB NP_752645.1 698146 R 199310 CDS NP_752646.1 26246606 1036877 698616..699410 1 NC_004431.1 Escherichia coli K-12 ortholog: b0626; Escherichia coli O157:H7 ortholog: z0771; amidase 699410 ybeM 1036877 ybeM Escherichia coli CFT073 amidase NP_752646.1 698616 D 199310 CDS NP_752647.1 26246607 1036793 699539..699742 1 NC_004431.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 699742 tatE 1036793 tatE Escherichia coli CFT073 twin arginine translocase protein E NP_752647.1 699539 D 199310 CDS NP_752648.1 26246608 1036894 complement(699842..700807) 1 NC_004431.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 700807 lipA 1036894 lipA Escherichia coli CFT073 lipoyl synthase NP_752648.1 699842 R 199310 CDS NP_752649.1 26246609 1036823 complement(701039..701380) 1 NC_004431.1 Residues 61 to 111 of 114 are 98.00 pct identical to residues 72 to 124 of 321 from MG1655 : b0629; hypothetical protein 701380 1036823 c0719 Escherichia coli CFT073 hypothetical protein NP_752649.1 701039 R 199310 CDS NP_752650.1 26246610 1036853 complement(701627..702268) 1 NC_004431.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 702268 lipB 1036853 lipB Escherichia coli CFT073 lipoate-protein ligase B NP_752650.1 701627 R 199310 CDS NP_752651.1 26246611 1036824 complement(702369..702632) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0631; Escherichia coli O157:H7 ortholog: z0776; hypothetical protein 702632 ybeD 1036824 ybeD Escherichia coli CFT073 hypothetical protein NP_752651.1 702369 R 199310 CDS NP_752652.1 26246612 1036908 complement(702742..703953) 1 NC_004431.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 703953 dacA 1036908 dacA Escherichia coli CFT073 D-alanyl-D-alanine carboxypeptidase fraction A NP_752652.1 702742 R 199310 CDS NP_752653.1 26246613 1036933 703991..704116 1 NC_004431.1 hypothetical protein 704116 1036933 c0723 Escherichia coli CFT073 hypothetical protein NP_752653.1 703991 D 199310 CDS NP_752654.1 26246614 1036857 complement(704093..705181) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0633; Escherichia coli O157:H7 ortholog: z0778; rare lipoprotein A 705181 rlpA 1036857 rlpA Escherichia coli CFT073 rare lipoprotein A NP_752654.1 704093 R 199310 CDS NP_752655.1 26246615 1036902 complement(705192..706304) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0634; Escherichia coli O157:H7 ortholog: z0780; cell wall shape-determining protein 706304 mrdB 1036902 mrdB Escherichia coli CFT073 cell wall shape-determining protein NP_752655.1 705192 R 199310 CDS NP_752656.1 26246616 1037029 complement(706307..708208) 1 NC_004431.1 PBP-2; Escherichia coli K-12 ortholog: b0635; Escherichia coli O157:H7 ortholog: z0781; penicillin-binding protein 2 708208 mrdA 1037029 mrdA Escherichia coli CFT073 penicillin-binding protein 2 NP_752656.1 706307 R 199310 CDS NP_752657.1 26246617 1036966 complement(708239..708706) 1 NC_004431.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 708706 ybeA 1036966 ybeA Escherichia coli CFT073 rRNA large subunit methyltransferase NP_752657.1 708239 R 199310 CDS NP_752658.1 26246618 1035925 complement(708710..709027) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0637; Escherichia coli O157:H7 ortholog: z0783; hypothetical protein 709027 ybeB 1035925 ybeB Escherichia coli CFT073 hypothetical protein NP_752658.1 708710 R 199310 CDS NP_752659.1 26246619 1037014 complement(709287..709901) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0638; Escherichia coli O157:H7 ortholog: z0785; alpha-ribazole-5'-phosphate phosphatase 709901 phpB 1037014 phpB Escherichia coli CFT073 alpha-ribazole-5'-phosphate phosphatase NP_752659.1 709287 R 199310 CDS NP_752660.1 26246620 1034961 complement(709922..710626) 1 NC_004431.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 710626 nadD 1034961 nadD Escherichia coli CFT073 nicotinic acid mononucleotide adenylyltransferase NP_752660.1 709922 R 199310 CDS NP_752661.1 26246621 1037044 complement(710565..711596) 1 NC_004431.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 711596 holA 1037044 holA Escherichia coli CFT073 DNA polymerase III subunit delta NP_752661.1 710565 R 199310 CDS NP_752662.1 26246622 1037058 complement(711596..712177) 1 NC_004431.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 712177 rlpB 1037058 rlpB Escherichia coli CFT073 LPS-assembly lipoprotein RlpB NP_752662.1 711596 R 199310 CDS NP_752663.1 26246623 1035928 complement(712192..714915) 1 NC_004431.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 714915 leuS 1035928 leuS Escherichia coli CFT073 leucyl-tRNA synthetase NP_752663.1 712192 R 199310 CDS NP_752664.1 26246624 1037141 715009..715491 1 NC_004431.1 Escherichia coli K-12 ortholog: b0643; Escherichia coli O157:H7 ortholog: z0790; hypothetical protein 715491 ybeL 1037141 ybeL Escherichia coli CFT073 hypothetical protein NP_752664.1 715009 D 199310 CDS NP_752665.2 161486285 1037100 complement(715536..716471) 1 NC_004431.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 716471 rihA 1037100 rihA Escherichia coli CFT073 ribonucleoside hydrolase 1 NP_752665.2 715536 R 199310 CDS NP_752666.1 26246626 1037153 complement(716589..717314) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0652; Escherichia coli O157:H7 ortholog: z0802; glutamate/aspartate transport ATP-binding protein gltL 717314 gltL 1037153 gltL Escherichia coli CFT073 glutamate/aspartate transport ATP-binding protein gltL NP_752666.1 716589 R 199310 CDS NP_752667.1 26246627 1037092 complement(717314..717988) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0653; Escherichia coli O157:H7 ortholog: z0803; glutamate/aspartate transport system permease gltK 717988 gltK 1037092 gltK Escherichia coli CFT073 glutamate/aspartate transport system permease gltK NP_752667.1 717314 R 199310 CDS NP_752668.1 26246628 1035918 complement(717988..718728) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0654; Escherichia coli O157:H7 ortholog: z0804; glutamate/aspartate transport system permease gltJ 718728 gltJ 1035918 gltJ Escherichia coli CFT073 glutamate/aspartate transport system permease gltJ NP_752668.1 717988 R 199310 CDS NP_752669.1 26246629 1037265 complement(718898..719875) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0655; Escherichia coli O157:H7 ortholog: z0805; glutamate and aspartate transporter subunit 719875 ybeJ 1037265 ybeJ Escherichia coli CFT073 glutamate and aspartate transporter subunit NP_752669.1 718898 R 199310 CDS NP_752670.1 26246630 1035926 719941..720063 1 NC_004431.1 hypothetical protein 720063 1035926 c0740 Escherichia coli CFT073 hypothetical protein NP_752670.1 719941 D 199310 CDS NP_752671.1 26246631 1038156 720260..722137 1 NC_004431.1 Residues 15 to 253 of 625 are 35.54 pct identical to residues 22 to 275 of 281 from GenPept.129 : >gb|AAA61597.1| (L28755) 2'-N-acetyltransferase [Providencia stuartii]; hypothetical protein 722137 1038156 c0741 Escherichia coli CFT073 hypothetical protein NP_752671.1 720260 D 199310 CDS NP_752672.1 26246632 1038228 complement(722215..723753) 1 NC_004431.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 723753 lnt 1038228 lnt Escherichia coli CFT073 apolipoprotein N-acyltransferase NP_752672.1 722215 R 199310 CDS NP_752673.1 26246633 1038236 complement(723778..724656) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0658; Escherichia coli O157:H7 ortholog: z0807; magnesium and cobalt efflux protein corC 724656 ybeX 1038236 ybeX Escherichia coli CFT073 magnesium and cobalt efflux protein corC NP_752673.1 723778 R 199310 CDS NP_752674.1 26246634 1038121 complement(724746..725213) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0659; Escherichia coli O157:H7 ortholog: z0808; metalloprotease 725213 ybeY 1038121 ybeY Escherichia coli CFT073 metalloprotease NP_752674.1 724746 R 199310 CDS NP_752675.1 26246635 1038262 complement(725210..726289) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0660; Escherichia coli O157:H7 ortholog: z0809; PhoH-like protein 726289 ybeZ 1038262 ybeZ Escherichia coli CFT073 PhoH-like protein NP_752675.1 725210 R 199310 CDS NP_752676.1 26246636 1038248 726269..726412 1 NC_004431.1 hypothetical protein 726412 1038248 c0746 Escherichia coli CFT073 hypothetical protein NP_752676.1 726269 D 199310 CDS NP_752677.1 26246637 1038259 complement(726403..727827) 1 NC_004431.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 727827 yleA 1038259 yleA Escherichia coli CFT073 (dimethylallyl)adenosine tRNA methylthiotransferase NP_752677.1 726403 R 199310 CDS NP_752678.2 161486284 1038240 727973..729148 1 NC_004431.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 729148 ubiF 1038240 ubiF Escherichia coli CFT073 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase NP_752678.2 727973 D 199310 CDS NP_752679.2 161486283 1035909 complement(730388..732052) 1 NC_004431.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 732052 asnB 1035909 asnB Escherichia coli CFT073 asparagine synthetase B NP_752679.2 730388 R 199310 CDS NP_752680.1 26246640 1040062 complement(732308..733060) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0675; Escherichia coli O157:H7 ortholog: z0822; UMP phosphatase 733060 nagD 1040062 nagD Escherichia coli CFT073 UMP phosphatase NP_752680.1 732308 R 199310 CDS NP_752681.1 26246641 1040199 complement(733108..734328) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0676; Escherichia coli O157:H7 ortholog: z0823; N-acetylglucosamine repressor 734328 nagC 1040199 nagC Escherichia coli CFT073 N-acetylglucosamine repressor NP_752681.1 733108 R 199310 CDS NP_752682.1 26246642 1040413 complement(734337..735485) 1 NC_004431.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 735485 nagA 1040413 nagA Escherichia coli CFT073 N-acetylglucosamine-6-phosphate deacetylase NP_752682.1 734337 R 199310 CDS NP_752683.1 26246643 1040280 complement(735545..736345) 1 NC_004431.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 736345 nagB 1040280 nagB Escherichia coli CFT073 glucosamine-6-phosphate deaminase NP_752683.1 735545 R 199310 CDS NP_752684.1 26246644 1036036 complement(736394..736528) 1 NC_004431.1 hypothetical protein 736528 1036036 c0754 Escherichia coli CFT073 hypothetical protein NP_752684.1 736394 R 199310 CDS NP_752685.1 26246645 1040298 736678..738624 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 738624 nagE 1040298 nagE Escherichia coli CFT073 PTS system N-acetyl glucosamine specific transporter subunits IIABC NP_752685.1 736678 D 199310 CDS NP_752686.1 26246646 1036580 complement(738594..738746) 1 NC_004431.1 hypothetical protein 738746 1036580 c0756 Escherichia coli CFT073 hypothetical protein NP_752686.1 738594 R 199310 CDS NP_752687.1 26246647 1036410 complement(738713..739993) 1 NC_004431.1 Residues 1 to 425 of 426 are 26.49 pct identical to residues 27 to 447 of 450 from GenPept.129 : >emb|CAD07871.1| (AL627278) possible membrane transport protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 739993 1036410 c0757 Escherichia coli CFT073 hypothetical protein NP_752687.1 738713 R 199310 CDS NP_752688.1 26246648 1039933 complement(740007..740477) 1 NC_004431.1 Residues 1 to 149 of 156 are 36.00 pct identical to residues 1 to 147 of 150 from GenPept.129 : >emb|CAD06928.1| (AL627283) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypthetical protein 740477 1039933 c0758 Escherichia coli CFT073 hypthetical protein NP_752688.1 740007 R 199310 CDS NP_752689.1 26246649 1035352 complement(740474..741643) 1 NC_004431.1 Residues 3 to 385 of 389 are 46.78 pct identical to residues 6 to 391 of 396 from GenPept.129 : >gb|AAL45764.1| (AE008932) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypthetical protein 741643 1035352 c0759 Escherichia coli CFT073 hypthetical protein NP_752689.1 740474 R 199310 CDS NP_752690.1 26246650 1035617 complement(741679..742437) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2832; Escherichia coli O157:H7 ortholog: z4150; hypothetical protein 742437 1035617 c0760 Escherichia coli CFT073 hypothetical protein NP_752690.1 741679 R 199310 CDS NP_752691.1 26246651 1035207 complement(742497..743384) 1 NC_004431.1 Residues 11 to 294 of 295 are 43.50 pct identical to residues 8 to 292 of 297 from GenPept.129 : >gb|AAL45759.1| (AE008931) dihydrodipicolinate synthase [Agrobacterium tumefaciens str. C58 (U. Washington)]; dihydrodipicolinate synthase 743384 1035207 c0761 Escherichia coli CFT073 dihydrodipicolinate synthase NP_752691.1 742497 R 199310 CDS NP_752692.1 26246652 1035126 complement(743388..744545) 1 NC_004431.1 Residues 11 to 378 of 385 are 33.87 pct identical to residues 33 to 399 of 399 from GenPept.129 : >gb|AAL13074.2| (AY052389) AttL [Agrobacterium tumefaciens]; alcohol dehydrogenase 744545 1035126 c0762 Escherichia coli CFT073 alcohol dehydrogenase NP_752692.1 743388 R 199310 CDS NP_752693.1 26246653 1035961 744820..745950 1 NC_004431.1 Residues 11 to 372 of 376 are 40.21 pct identical to residues 41 to 418 of 423 from GenPept.129 : >gb|AAL19126.1| (AE008701) inner membrane protein [Salmonella typhimurium LT2]; inner membrane protein 745950 1035961 c0763 Escherichia coli CFT073 inner membrane protein NP_752693.1 744820 D 199310 CDS NP_752694.1 26246654 1035397 745943..746929 1 NC_004431.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 746929 pdxA 1035397 pdxA Escherichia coli CFT073 4-hydroxythreonine-4-phosphate dehydrogenase NP_752694.1 745943 D 199310 CDS NP_752695.1 26246655 1035396 746931..747692 1 NC_004431.1 LysR family; Residues 1 to 234 of 253 are 70.08 pct identical to residues 1 to 234 of 255 from GenPept.129 : >gb|AAL19128.1| (AE008701) transcriptional regulator (LysR family) [Salmonella typhimurium LT2]; transcriptional regulator 747692 1035396 c0765 Escherichia coli CFT073 transcriptional regulator NP_752695.1 746931 D 199310 CDS NP_752696.1 26246656 1040092 747912..749576 1 NC_004431.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 749576 glnS 1040092 glnS Escherichia coli CFT073 glutaminyl-tRNA synthetase NP_752696.1 747912 D 199310 CDS NP_752697.1 26246657 1035950 749807..750265 1 NC_004431.1 Residues 1 to 152 of 152 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 750265 1035950 c0767 Escherichia coli CFT073 hypothetical protein NP_752697.1 749807 D 199310 CDS NP_752698.1 26246658 1036235 750730..752136 1 NC_004431.1 Escherichia coli K-12 ortholog: b0681; Escherichia coli O157:H7 ortholog: z0829; hypothetical protein 752136 ybfM 1036235 ybfM Escherichia coli CFT073 hypothetical protein NP_752698.1 750730 D 199310 CDS NP_752699.1 26246659 1038176 752186..752512 1 NC_004431.1 Escherichia coli K-12 ortholog: b0682; Escherichia coli O157:H7 ortholog: z0830; lipoprotein ybfN 752512 ybfN 1038176 ybfN Escherichia coli CFT073 lipoprotein ybfN NP_752699.1 752186 D 199310 CDS NP_752700.1 26246660 1037658 complement(752596..753042) 1 NC_004431.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 753042 fur 1037658 fur Escherichia coli CFT073 ferric uptake regulator NP_752700.1 752596 R 199310 CDS NP_752701.2 161486282 1035998 complement(753331..753861) 1 NC_004431.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 753861 fldA 1035998 fldA Escherichia coli CFT073 flavodoxin FldA NP_752701.2 753331 R 199310 CDS NP_752702.1 26246662 1035980 complement(754001..754363) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0685; Escherichia coli O157:H7 ortholog: z0834; LexA regulated protein 754363 ybfE 1035980 ybfE Escherichia coli CFT073 LexA regulated protein NP_752702.1 754001 R 199310 CDS NP_752703.1 26246663 1037693 complement(754434..755198) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0686; Escherichia coli O157:H7 ortholog: z0835; hypothetical protein 755198 ybfF 1037693 ybfF Escherichia coli CFT073 hypothetical protein NP_752703.1 754434 R 199310 CDS NP_752704.2 161486281 1036013 755383..755928 1 NC_004431.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 755928 seqA 1036013 seqA Escherichia coli CFT073 replication initiation regulator SeqA NP_752704.2 755383 D 199310 CDS NP_752705.1 26246665 1036333 755903..757594 1 NC_004431.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 757594 pgm 1036333 pgm Escherichia coli CFT073 phosphoglucomutase NP_752705.1 755903 D 199310 CDS NP_752706.1 26246666 1036030 complement(757651..758970) 1 NC_004431.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 758970 potE 1036030 potE Escherichia coli CFT073 putrescine transporter NP_752706.1 757651 R 199310 CDS NP_752707.1 26246667 1036141 complement(758967..761174) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0693; Escherichia coli O157:H7 ortholog: z0839; ornithine decarboxylase 761174 speF 1036141 speF Escherichia coli CFT073 ornithine decarboxylase NP_752707.1 758967 R 199310 CDS NP_752708.1 26246668 1036943 complement(761179..761331) 1 NC_004431.1 hypothetical protein 761331 1036943 c0778 Escherichia coli CFT073 hypothetical protein NP_752708.1 761179 R 199310 CDS NP_752709.1 26246669 1035398 complement(761791..762468) 1 NC_004431.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 762468 kdpE 1035398 kdpE Escherichia coli CFT073 DNA-binding transcriptional activator KdpE NP_752709.1 761791 R 199310 CDS NP_752710.1 26246670 1035720 complement(762465..765152) 1 NC_004431.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 765152 kdpD 1035720 kdpD Escherichia coli CFT073 sensor protein KdpD NP_752710.1 762465 R 199310 CDS NP_752711.1 26246671 1036279 complement(765142..765738) 1 NC_004431.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 765738 kdpC 1036279 kdpC Escherichia coli CFT073 potassium-transporting ATPase subunit C NP_752711.1 765142 R 199310 CDS NP_752712.1 26246672 1035814 complement(765723..767771) 1 NC_004431.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 767771 kdpB 1035814 kdpB Escherichia coli CFT073 potassium-transporting ATPase subunit B NP_752712.1 765723 R 199310 CDS NP_752713.1 26246673 1036015 complement(767794..769467) 1 NC_004431.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 769467 kdpA 1036015 kdpA Escherichia coli CFT073 potassium-transporting ATPase subunit A NP_752713.1 767794 R 199310 CDS NP_752714.1 26246674 1035605 complement(769467..769670) 1 NC_004431.1 Residues 39 to 67 of 67 are 93.10 pct identical to residues 1 to 29 of 29 from GenPept.129 : >dbj|BAA35357.1| (D90709) KdpF protein. [Escherichia coli]; hypothetical protein 769670 1035605 c0784 Escherichia coli CFT073 hypothetical protein NP_752714.1 769467 R 199310 CDS NP_752715.1 26246675 1036018 769869..770075 1 NC_004431.1 Escherichia coli K-12 ortholog: b0699; Escherichia coli O157:H7 ortholog: z0846; hypothetical protein 770075 ybfA 1036018 ybfA Escherichia coli CFT073 hypothetical protein NP_752715.1 769869 D 199310 CDS NP_752716.1 26246676 1036722 770176..770685 1 NC_004431.1 TKP; Escherichia coli K-12 ortholog: b0707; Escherichia coli O157:H7 ortholog: z0858; hypothetical protein 770685 ybgA 1036722 ybgA Escherichia coli CFT073 hypothetical protein NP_752716.1 770176 D 199310 CDS NP_752717.1 26246677 1035982 770682..772100 1 NC_004431.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 772100 phrB 1035982 phrB Escherichia coli CFT073 deoxyribodipyrimidine photolyase NP_752717.1 770682 D 199310 CDS NP_752718.1 26246678 1036919 complement(772142..773623) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0709; Escherichia coli O157:H7 ortholog: z0860; transporter YbgH 773623 ybgH 1036919 ybgH Escherichia coli CFT073 transporter YbgH NP_752718.1 772142 R 199310 CDS NP_752719.1 26246679 1036967 773894..774637 1 NC_004431.1 Escherichia coli K-12 ortholog: b0710; Escherichia coli O157:H7 ortholog: z0861; hydrolase-oxidase 774637 ybgI 1036967 ybgI Escherichia coli CFT073 hydrolase-oxidase NP_752719.1 773894 D 199310 CDS NP_752720.1 26246680 1035996 774660..775316 1 NC_004431.1 Escherichia coli K-12 ortholog: b0711; Escherichia coli O157:H7 ortholog: z0862; hypothetical protein 775316 ybgJ 1035996 ybgJ Escherichia coli CFT073 hypothetical protein NP_752720.1 774660 D 199310 CDS NP_752721.1 26246681 1035978 775310..776242 1 NC_004431.1 Escherichia coli K-12 ortholog: b0712; Escherichia coli O157:H7 ortholog: z0863; hypothetical protein 776242 ybgK 1035978 ybgK Escherichia coli CFT073 hypothetical protein NP_752721.1 775310 D 199310 CDS NP_752722.1 26246682 1036862 776232..776966 1 NC_004431.1 Escherichia coli K-12 ortholog: b0713; Escherichia coli O157:H7 ortholog: z0864; LamB/YcsF family protein 776966 ybgL 1036862 ybgL Escherichia coli CFT073 LamB/YcsF family protein NP_752722.1 776232 D 199310 CDS NP_752723.1 26246683 1035763 777002..777793 1 NC_004431.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 777793 nei 1035763 nei Escherichia coli CFT073 endonuclease VIII NP_752723.1 777002 D 199310 CDS NP_752724.1 26246684 1036844 complement(777790..778881) 1 NC_004431.1 AidB regulator; Escherichia coli K-12 ortholog: b0715; Escherichia coli O157:H7 ortholog: z0867; AbrB protein 778881 abrB 1036844 abrB Escherichia coli CFT073 AbrB protein NP_752724.1 777790 R 199310 CDS NP_752725.1 26246685 1040361 complement(779120..779362) 1 NC_004431.1 Residues 1 to 80 of 80 are 94.99 pct identical to residues 239 to 318 of 362 from MG1655 : b0716; hypothetical protein 779362 1040361 c0795 Escherichia coli CFT073 hypothetical protein NP_752725.1 779120 R 199310 CDS NP_752726.1 26246686 1036856 complement(779510..780793) 1 NC_004431.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 780793 gltA 1036856 gltA Escherichia coli CFT073 type II citrate synthase NP_752726.1 779510 R 199310 CDS NP_752727.1 26246687 1035346 780775..780966 1 NC_004431.1 Residues 27 to 63 of 63 are 67.56 pct identical to residues 2 to 38 of 81 from GenPept.129 : >emb|CAD05193.1| (AL627268) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 780966 1035346 c0797 Escherichia coli CFT073 hypothetical protein NP_752727.1 780775 D 199310 CDS NP_752728.2 161486280 1036744 781502..781891 1 NC_004431.1 Escherichia coli K-12 ortholog: b0721; Escherichia coli O157:H7 ortholog: z0875; succinate dehydrogenase cytochrome b556 large membrane subunit 781891 sdhC 1036744 sdhC Escherichia coli CFT073 succinate dehydrogenase cytochrome b556 large membrane subunit NP_752728.2 781502 D 199310 CDS NP_752729.1 26246689 1039949 complement(781544..781774) 1 NC_004431.1 hypothetical protein 781774 1039949 c0799 Escherichia coli CFT073 hypothetical protein NP_752729.1 781544 R 199310 CDS NP_752730.1 26246690 1039528 781885..782232 1 NC_004431.1 Escherichia coli K-12 ortholog: b0722; Escherichia coli O157:H7 ortholog: z0876; succinate dehydrogenase cytochrome b556 small membrane subunit 782232 sdhD 1039528 sdhD Escherichia coli CFT073 succinate dehydrogenase cytochrome b556 small membrane subunit NP_752730.1 781885 D 199310 CDS NP_752731.2 161486279 1039505 782232..783998 1 NC_004431.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 783998 sdhA 1039505 sdhA Escherichia coli CFT073 succinate dehydrogenase flavoprotein subunit NP_752731.2 782232 D 199310 CDS NP_752732.1 26246692 1040343 784014..784730 1 NC_004431.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 784730 sdhB 1040343 sdhB Escherichia coli CFT073 succinate dehydrogenase iron-sulfur subunit NP_752732.1 784014 D 199310 CDS NP_752733.1 26246693 1035834 785281..788082 1 NC_004431.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 788082 sucA 1035834 sucA Escherichia coli CFT073 2-oxoglutarate dehydrogenase E1 NP_752733.1 785281 D 199310 CDS NP_752734.1 26246694 1036634 788097..789314 1 NC_004431.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 789314 sucB 1036634 sucB Escherichia coli CFT073 dihydrolipoamide succinyltransferase NP_752734.1 788097 D 199310 CDS NP_752735.1 26246695 1039366 789408..790574 1 NC_004431.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 790574 sucC 1039366 sucC Escherichia coli CFT073 succinyl-CoA synthetase subunit beta NP_752735.1 789408 D 199310 CDS NP_752736.1 26246696 1040403 790574..791443 1 NC_004431.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 791443 sucD 1040403 sucD Escherichia coli CFT073 succinyl-CoA synthetase subunit alpha NP_752736.1 790574 D 199310 CDS NP_752737.1 26246697 1039950 791683..792642 1 NC_004431.1 Residues 16 to 223 of 319 are 32.74 pct identical to residues 1594 to 1812 of 1819 from GenPept.129 : >gb|AAK79055.1|AE007624_2 (AE007624) Uncharacterized protein, probably surface-located [Clostridium acetobutylicum]; hypothetical protein 792642 1039950 c0807 Escherichia coli CFT073 hypothetical protein NP_752737.1 791683 D 199310 CDS NP_752738.1 26246698 1040334 792671..793024 1 NC_004431.1 hypothetical protein 793024 1040334 c0808 Escherichia coli CFT073 hypothetical protein NP_752738.1 792671 D 199310 CDS NP_752739.1 26246699 1035835 complement(793092..793214) 1 NC_004431.1 hypothetical protein 793214 1035835 c0809 Escherichia coli CFT073 hypothetical protein NP_752739.1 793092 R 199310 CDS NP_752740.1 26246700 1039140 complement(793232..793378) 1 NC_004431.1 hypothetical protein 793378 1039140 c0810 Escherichia coli CFT073 hypothetical protein NP_752740.1 793232 R 199310 CDS NP_752741.1 26246701 1035833 794125..795696 1 NC_004431.1 Escherichia coli K-12 ortholog: b0733; Escherichia coli O157:H7 ortholog: z0900; cytochrome D ubiquinol oxidase subunit I 795696 cydA 1035833 cydA Escherichia coli CFT073 cytochrome D ubiquinol oxidase subunit I NP_752741.1 794125 D 199310 CDS NP_752742.1 26246702 1038924 795712..796851 1 NC_004431.1 Escherichia coli K-12 ortholog: b0734; Escherichia coli O157:H7 ortholog: z0901; cytochrome D ubiquinol oxidase subunit II 796851 cydB 1038924 cydB Escherichia coli CFT073 cytochrome D ubiquinol oxidase subunit II NP_752742.1 795712 D 199310 CDS NP_752743.1 26246703 1039020 complement(795766..796881) 1 NC_004431.1 hypothetical protein 796881 1039020 c0813 Escherichia coli CFT073 hypothetical protein NP_752743.1 795766 R 199310 CDS NP_752744.1 26246704 1039436 796979..797272 1 NC_004431.1 Escherichia coli K-12 ortholog: b0735; Escherichia coli O157:H7 ortholog: z0903; hypothetical protein 797272 ybgE 1039436 ybgE Escherichia coli CFT073 hypothetical protein NP_752744.1 796979 D 199310 CDS NP_752745.1 26246705 1039037 797422..797826 1 NC_004431.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 797826 ybgC 1039037 ybgC Escherichia coli CFT073 acyl-CoA thioester hydrolase NP_752745.1 797422 D 199310 CDS NP_752746.1 26246706 1039008 797823..798515 1 NC_004431.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 798515 tolQ 1039008 tolQ Escherichia coli CFT073 colicin uptake protein TolQ NP_752746.1 797823 D 199310 CDS NP_752747.1 26246707 1038834 798519..798947 1 NC_004431.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 798947 tolR 1038834 tolR Escherichia coli CFT073 colicin uptake protein TolR NP_752747.1 798519 D 199310 CDS NP_752748.1 26246708 1039041 799012..800277 1 NC_004431.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 800277 tolA 1039041 tolA Escherichia coli CFT073 cell envelope integrity inner membrane protein TolA NP_752748.1 799012 D 199310 CDS NP_752749.1 26246709 1038911 800407..801702 1 NC_004431.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 801702 tolB 1038911 tolB Escherichia coli CFT073 translocation protein TolB NP_752749.1 800407 D 199310 CDS NP_752750.1 26246710 1038903 complement(801671..802291) 1 NC_004431.1 hypothetical protein 802291 1038903 c0820 Escherichia coli CFT073 hypothetical protein NP_752750.1 801671 R 199310 CDS NP_752751.1 26246711 1038851 801713..802258 1 NC_004431.1 Escherichia coli K-12 ortholog: b0741; Escherichia coli O157:H7 ortholog: z0909; peptidoglycan-associated outer membrane lipoprotein 802258 pal 1038851 pal Escherichia coli CFT073 peptidoglycan-associated outer membrane lipoprotein NP_752751.1 801713 D 199310 CDS NP_752752.1 26246712 1036640 802268..802933 1 NC_004431.1 Escherichia coli K-12 ortholog: b0742; Escherichia coli O157:H7 ortholog: z0910; hypothetical protein 802933 ybgF 1036640 ybgF Escherichia coli CFT073 hypothetical protein NP_752752.1 802268 D 199310 CDS NP_752753.1 26246713 1038672 802857..803060 1 NC_004431.1 Residues 5 to 67 of 67 are 100.00 pct identical to residues 201 to 263 of 263 from MG1655 : b0742; hypothetical protein 803060 1038672 c0823 Escherichia coli CFT073 hypothetical protein NP_752753.1 802857 D 199310 CDS NP_752754.1 26246714 1038817 complement(802905..803204) 1 NC_004431.1 hypothetical protein 803204 1038817 c0824 Escherichia coli CFT073 hypothetical protein NP_752754.1 802905 R 199310 CDS NP_752755.1 26246715 1039955 804206..805249 1 NC_004431.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 805249 nadA 1039955 nadA Escherichia coli CFT073 quinolinate synthetase NP_752755.1 804206 D 199310 CDS NP_752756.1 26246716 1038277 805287..806006 1 NC_004431.1 Escherichia coli K-12 ortholog: b0751; Escherichia coli O157:H7 ortholog: z0920; protein pnuC 806006 pnuC 1038277 pnuC Escherichia coli CFT073 protein pnuC NP_752756.1 805287 D 199310 CDS NP_752757.1 26246717 1038410 complement(806003..806401) 1 NC_004431.1 Residues 10 to 132 of 132 are 98.37 pct identical to residues 191 to 313 of 313 from MG1655 : b0752; hypothetical protein 806401 1038410 c0827 Escherichia coli CFT073 hypothetical protein NP_752757.1 806003 R 199310 CDS NP_752758.1 26246718 1038646 806488..806919 1 NC_004431.1 hypothetical protein 806919 1038646 c0828 Escherichia coli CFT073 hypothetical protein NP_752758.1 806488 D 199310 CDS NP_752759.1 26246719 1038488 complement(806505..806885) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0753; Escherichia coli O157:H7 ortholog: z0923; hypothetical protein 806885 ybgS 1038488 ybgS Escherichia coli CFT073 hypothetical protein NP_752759.1 806505 R 199310 CDS NP_752760.1 26246720 1038119 807201..808253 1 NC_004431.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 808253 aroG 1038119 aroG Escherichia coli CFT073 phospho-2-dehydro-3-deoxyheptonate aldolase NP_752760.1 807201 D 199310 CDS NP_752761.1 26246721 1037999 complement(808419..809186) 1 NC_004431.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 809186 gpmA 1037999 gpmA Escherichia coli CFT073 phosphoglyceromutase NP_752761.1 808419 R 199310 CDS NP_752762.1 26246722 1038053 complement(809374..810414) 1 NC_004431.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 810414 galM 1038053 galM Escherichia coli CFT073 aldose 1-epimerase NP_752762.1 809374 R 199310 CDS NP_752763.1 26246723 1038288 complement(810408..811556) 1 NC_004431.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 811556 galK 1038288 galK Escherichia coli CFT073 galactokinase NP_752763.1 810408 R 199310 CDS NP_752764.1 26246724 1037875 complement(811560..812606) 1 NC_004431.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 812606 galT 1037875 galT Escherichia coli CFT073 galactose-1-phosphate uridylyltransferase NP_752764.1 811560 R 199310 CDS NP_752765.1 26246725 1036650 complement(812616..813632) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0759; Escherichia coli O157:H7 ortholog: z0929; UDP-galactose-4-epimerase 813632 galE 1036650 galE Escherichia coli CFT073 UDP-galactose-4-epimerase NP_752765.1 812616 R 199310 CDS NP_752766.2 161486278 1037980 complement(813894..815366) 1 NC_004431.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 815366 modF 1037980 modF Escherichia coli CFT073 molybdenum transport ATP-binding protein ModF NP_752766.2 813894 R 199310 CDS NP_752767.1 26246727 1039959 complement(815434..816222) 1 NC_004431.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 816222 modE 1039959 modE Escherichia coli CFT073 DNA-binding transcriptional regulator ModE NP_752767.1 815434 R 199310 CDS NP_752768.1 26246728 1038066 816345..816500 1 NC_004431.1 Escherichia coli K-12 ortholog: b0762; Escherichia coli O157:H7 ortholog: z0932; hypothetical protein 816500 ybhT 1038066 ybhT Escherichia coli CFT073 hypothetical protein NP_752768.1 816345 D 199310 CDS NP_752769.1 26246729 1037847 816436..816645 1 NC_004431.1 hypothetical protein 816645 1037847 c0839 Escherichia coli CFT073 hypothetical protein NP_752769.1 816436 D 199310 CDS NP_752770.1 26246730 1037955 816667..817440 1 NC_004431.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 817440 modA 1037955 modA Escherichia coli CFT073 molybdate transporter periplasmic protein NP_752770.1 816667 D 199310 CDS NP_752771.1 26246731 1037798 817440..818129 1 NC_004431.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 818129 modB 1037798 modB Escherichia coli CFT073 molybdate ABC transporter permease NP_752771.1 817440 D 199310 CDS NP_752772.1 26246732 1037777 818132..819190 1 NC_004431.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 819190 modC 1037777 modC Escherichia coli CFT073 molybdate transporter ATP-binding protein NP_752772.1 818132 D 199310 CDS NP_752773.1 26246733 1037728 complement(819191..820009) 1 NC_004431.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 820009 ybhA 1037728 ybhA Escherichia coli CFT073 phosphotransferase NP_752773.1 819191 R 199310 CDS NP_752774.1 26246734 1035826 820164..821159 1 NC_004431.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 821159 ybhE 1035826 ybhE Escherichia coli CFT073 6-phosphogluconolactonase NP_752774.1 820164 D 199310 CDS NP_752775.1 26246735 1037699 complement(821200..822216) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0768; Escherichia coli O157:H7 ortholog: z0939; transcriptional regulator YbhD 822216 ybhD 1037699 ybhD Escherichia coli CFT073 transcriptional regulator YbhD NP_752775.1 821200 R 199310 CDS NP_752776.1 26246736 1035824 822337..823389 1 NC_004431.1 Escherichia coli K-12 ortholog: b0769; Escherichia coli O157:H7 ortholog: z0940; hypothetical protein 823389 ybhH 1035824 ybhH Escherichia coli CFT073 hypothetical protein NP_752776.1 822337 D 199310 CDS NP_752777.1 26246737 1036654 823465..824898 1 NC_004431.1 Escherichia coli K-12 ortholog: b0770; Escherichia coli O157:H7 ortholog: z0941; hypothetical protein 824898 ybhI 1036654 ybhI Escherichia coli CFT073 hypothetical protein NP_752777.1 823465 D 199310 CDS NP_752778.2 161486277 1038048 825081..827342 1 NC_004431.1 Escherichia coli K-12 ortholog: b0771; Escherichia coli O157:H7 ortholog: z0942; hypothetical protein 827342 ybhJ 1038048 ybhJ Escherichia coli CFT073 hypothetical protein NP_752778.2 825081 D 199310 CDS NP_752779.1 26246739 1037715 complement(827482..828765) 1 NC_004431.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 828765 ybhC 1037715 ybhC Escherichia coli CFT073 pectinesterase NP_752779.1 827482 R 199310 CDS NP_752780.1 26246740 1035822 complement(828917..829393) 1 NC_004431.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 829393 ybhB 1035822 ybhB Escherichia coli CFT073 kinase inhibitor protein NP_752780.1 828917 R 199310 CDS NP_752781.1 26246741 1037757 829502..830632 1 NC_004431.1 Residues 1 to 373 of 376 are 54.52 pct identical to residues 5 to 379 of 402 from SwissProt.40 : >sp|P54992|YSNA_STRPR Hypothetical 45.4 kDa protein in SNAA-SNAB intergenic region (ORF401); Peyer's patch-specific virulence factor GipA 830632 gipA 1037757 gipA Escherichia coli CFT073 Peyer's patch-specific virulence factor GipA NP_752781.1 829502 D 199310 CDS NP_752782.1 26246742 1037735 complement(829652..829858) 1 NC_004431.1 hypothetical protein 829858 1037735 c0852 Escherichia coli CFT073 hypothetical protein NP_752782.1 829652 R 199310 CDS NP_752783.2 161486276 1037742 complement(830743..832032) 1 NC_004431.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 832032 bioA 1037742 bioA Escherichia coli CFT073 adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_752783.2 830743 R 199310 CDS NP_752784.1 26246744 1037705 830809..831006 1 NC_004431.1 hypothetical protein 831006 1037705 c0854 Escherichia coli CFT073 hypothetical protein NP_752784.1 830809 D 199310 CDS NP_752785.1 26246745 1037718 832119..833159 1 NC_004431.1 Escherichia coli K-12 ortholog: b0775; Escherichia coli O157:H7 ortholog: z0994; biotin synthase 833159 bioB 1037718 bioB Escherichia coli CFT073 biotin synthase NP_752785.1 832119 D 199310 CDS NP_752786.1 26246746 1039962 833156..834310 1 NC_004431.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 834310 bioF 1039962 bioF Escherichia coli CFT073 8-amino-7-oxononanoate synthase NP_752786.1 833156 D 199310 CDS NP_752788.1 26246748 1036660 835045..835722 1 NC_004431.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 835722 bioD 1036660 bioD Escherichia coli CFT073 dithiobiotin synthetase NP_752788.1 835045 D 199310 CDS NP_752789.1 26246749 1037741 complement(835889..836026) 1 NC_004431.1 hypothetical protein 836026 1037741 c0859 Escherichia coli CFT073 hypothetical protein NP_752789.1 835889 R 199310 CDS NP_752790.1 26246750 1037760 836301..838322 1 NC_004431.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 838322 uvrB 1037760 uvrB Escherichia coli CFT073 excinuclease ABC subunit B NP_752790.1 836301 D 199310 CDS NP_752791.1 26246751 1037727 complement(838360..839328) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0780; Escherichia coli O157:H7 ortholog: z0999; hypothetical protein 839328 ybhK 1037727 ybhK Escherichia coli CFT073 hypothetical protein NP_752791.1 838360 R 199310 CDS NP_752792.1 26246752 1036662 839584..840654 1 NC_004431.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 840654 moaA 1036662 moaA Escherichia coli CFT073 molybdenum cofactor biosynthesis protein A NP_752792.1 839584 D 199310 CDS NP_752793.1 26246753 1037746 840676..841188 1 NC_004431.1 Escherichia coli K-12 ortholog: b0782; Escherichia coli O157:H7 ortholog: z1001; molybdenum cofactor biosynthesis protein B 841188 moaB 1037746 moaB Escherichia coli CFT073 molybdenum cofactor biosynthesis protein B NP_752793.1 840676 D 199310 CDS NP_752794.1 26246754 1037755 complement(840930..841421) 1 NC_004431.1 hypothetical protein 841421 1037755 c0864 Escherichia coli CFT073 hypothetical protein NP_752794.1 840930 R 199310 CDS NP_752795.1 26246755 1040472 841191..841676 1 NC_004431.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 841676 moaC 1040472 moaC Escherichia coli CFT073 molybdenum cofactor biosynthesis protein MoaC NP_752795.1 841191 D 199310 CDS NP_752796.2 161486275 1037756 841669..841914 1 NC_004431.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 841914 moaD 1037756 moaD Escherichia coli CFT073 molybdopterin synthase small subunit NP_752796.2 841669 D 199310 CDS NP_752797.1 26246757 1037772 841916..842368 1 NC_004431.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 842368 moaE 1037772 moaE Escherichia coli CFT073 molybdopterin guanine dinucleotide biosynthesis protein MoaE NP_752797.1 841916 D 199310 CDS NP_752798.1 26246758 1037790 842424..843209 1 NC_004431.1 Escherichia coli K-12 ortholog: b0786; Escherichia coli O157:H7 ortholog: z1005; hypothetical protein 843209 ybhL 1037790 ybhL Escherichia coli CFT073 hypothetical protein NP_752798.1 842424 D 199310 CDS NP_752799.1 26246759 1037796 complement(843141..843272) 1 NC_004431.1 Residues 6 to 43 of 43 are 94.73 pct identical to residues 8 to 45 of 45 from GenPept.129 : >dbj|BAA35445.1| (D90716) ORF_ID:o203#8 [Escherichia coli]; hypothetical protein 843272 1037796 c0869 Escherichia coli CFT073 hypothetical protein NP_752799.1 843141 R 199310 CDS NP_752800.1 26246760 1037773 843388..844128 1 NC_004431.1 Escherichia coli K-12 ortholog: b0787; Escherichia coli O157:H7 ortholog: z1006; hypothetical protein 844128 ybhM 1037773 ybhM Escherichia coli CFT073 hypothetical protein NP_752800.1 843388 D 199310 CDS NP_752801.1 26246761 1037771 complement(844164..845120) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0788; Escherichia coli O157:H7 ortholog: z1007; hypothetical protein 845120 ybhN 1037771 ybhN Escherichia coli CFT073 hypothetical protein NP_752801.1 844164 R 199310 CDS NP_752802.1 26246762 1037779 complement(845120..846361) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0789; Escherichia coli O157:H7 ortholog: z1008; cardiolipin synthase 2 846361 ybhO 1037779 ybhO Escherichia coli CFT073 cardiolipin synthase 2 NP_752802.1 845120 R 199310 CDS NP_752803.1 26246763 1037799 complement(846358..847119) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0790; Escherichia coli O157:H7 ortholog: z1009; hypothetical protein 847119 ybhP 1037799 ybhP Escherichia coli CFT073 hypothetical protein NP_752803.1 846358 R 199310 CDS NP_752804.1 26246764 1037805 847252..847662 1 NC_004431.1 Escherichia coli K-12 ortholog: b0791; Escherichia coli O157:H7 ortholog: z1010; hypothetical protein 847662 ybhQ 1037805 ybhQ Escherichia coli CFT073 hypothetical protein NP_752804.1 847252 D 199310 CDS NP_752805.1 26246765 1035809 complement(847624..848730) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0792; Escherichia coli O157:H7 ortholog: z1012; hypothetical protein 848730 ybhR 1035809 ybhR Escherichia coli CFT073 hypothetical protein NP_752805.1 847624 R 199310 CDS NP_752806.1 26246766 1037834 complement(848741..849874) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0793; Escherichia coli O157:H7 ortholog: z1013; hypothetical protein 849874 ybhS 1037834 ybhS Escherichia coli CFT073 hypothetical protein NP_752806.1 848741 R 199310 CDS NP_752807.1 26246767 1035802 complement(849867..851618) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0794; Escherichia coli O157:H7 ortholog: z1014; ABC transporter ATP-binding protein 851618 ybhF 1035802 ybhF Escherichia coli CFT073 ABC transporter ATP-binding protein NP_752807.1 849867 R 199310 CDS NP_752808.1 26246768 1037815 complement(851596..852594) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0795; Escherichia coli O157:H7 ortholog: z1015; hypothetical protein 852594 ybhG 1037815 ybhG Escherichia coli CFT073 hypothetical protein NP_752808.1 851596 R 199310 CDS NP_752809.1 26246769 1037808 complement(852594..853277) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0796; Escherichia coli O157:H7 ortholog: z1016; DNA-binding transcriptional regulator 853277 ybiH 1037808 ybiH Escherichia coli CFT073 DNA-binding transcriptional regulator NP_752809.1 852594 R 199310 CDS NP_752810.1 26246770 1037845 853494..854855 1 NC_004431.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 854855 rhlE 1037845 rhlE Escherichia coli CFT073 ATP-dependent RNA helicase RhlE NP_752810.1 853494 D 199310 CDS YP_004853797.1 347357906 1036691 complement(854932..855072) 1 NC_004431.1 hypothetical protein 855072 1036691 c0881 Escherichia coli CFT073 hypothetical protein YP_004853797.1 854932 R 199310 CDS NP_752812.1 26246772 1035803 complement(855088..855393) 1 NC_004431.1 Residues 32 to 101 of 101 are 80.00 pct identical to residues 91 to 160 of 160 from MG1655 : b0798; hypothetical protein 855393 1035803 c0882 Escherichia coli CFT073 hypothetical protein NP_752812.1 855088 R 199310 CDS NP_752813.1 26246773 1037800 855392..857542 1 NC_004431.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 857542 dinG 1037800 dinG Escherichia coli CFT073 ATP-dependent DNA helicase DinG NP_752813.1 855392 D 199310 CDS NP_752814.1 26246774 1037851 857570..858532 1 NC_004431.1 Escherichia coli K-12 ortholog: b0800; Escherichia coli O157:H7 ortholog: z1021; glycosyl transferase family protein 858532 ybiB 1037851 ybiB Escherichia coli CFT073 glycosyl transferase family protein NP_752814.1 857570 D 199310 CDS NP_752815.1 26246775 1037826 858673..859758 1 NC_004431.1 Escherichia coli K-12 ortholog: b0801; Escherichia coli O157:H7 ortholog: z1022; hypothetical protein 859758 ybiC 1037826 ybiC Escherichia coli CFT073 hypothetical protein NP_752815.1 858673 D 199310 CDS NP_752816.1 26246776 1037831 complement(859986..860246) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0802; Escherichia coli O157:H7 ortholog: z1023; hypothetical protein 860246 ybiJ 1037831 ybiJ Escherichia coli CFT073 hypothetical protein NP_752816.1 859986 R 199310 CDS YP_004853798.1 347357907 1039966 complement(860501..860866) 1 NC_004431.1 hypothetical protein 860866 1039966 c0887 Escherichia coli CFT073 hypothetical protein YP_004853798.1 860501 R 199310 CDS NP_752818.1 26246778 1035788 complement(860511..860777) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024; hypothetical protein 860777 1035788 c0888 Escherichia coli CFT073 hypothetical protein NP_752818.1 860511 R 199310 CDS NP_752819.2 161486274 1037849 complement(860851..861528) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0804; Escherichia coli O157:H7 ortholog: z1025; hydroxylase 861528 ybiX 1037849 ybiX Escherichia coli CFT073 hydroxylase NP_752819.2 860851 R 199310 CDS NP_752820.1 26246780 1037863 complement(861744..864026) 1 NC_004431.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 864026 ybiL 1037863 ybiL Escherichia coli CFT073 catecholate siderophore receptor Fiu NP_752820.1 861744 R 199310 CDS NP_752821.1 26246781 1037841 complement(864291..864695) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0806; Escherichia coli O157:H7 ortholog: z1027; hypothetical protein 864695 ybiM 1037841 ybiM Escherichia coli CFT073 hypothetical protein NP_752821.1 864291 R 199310 CDS NP_752822.1 26246782 1037684 864737..865753 1 NC_004431.1 Escherichia coli K-12 ortholog: b0807; Escherichia coli O157:H7 ortholog: z1028; SAM-dependent methyltransferase 865753 ybiN 1037684 ybiN Escherichia coli CFT073 SAM-dependent methyltransferase NP_752822.1 864737 D 199310 CDS NP_752823.2 161486273 1037837 complement(865750..867975) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0808; Escherichia coli O157:H7 ortholog: z1030; hypothetical protein 867975 ybiO 1037837 ybiO Escherichia coli CFT073 hypothetical protein NP_752823.2 865750 R 199310 CDS NP_752824.1 26246784 1037899 complement(868092..868814) 1 NC_004431.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 868814 glnQ 1037899 glnQ Escherichia coli CFT073 glutamine ABC transporter ATP-binding protein NP_752824.1 868092 R 199310 CDS NP_752825.1 26246785 1037881 complement(868811..869470) 1 NC_004431.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 869470 glnP 1037881 glnP Escherichia coli CFT073 glutamine ABC transporter permease NP_752825.1 868811 R 199310 CDS NP_752826.1 26246786 1037866 complement(869609..870355) 1 NC_004431.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 870355 glnH 1037866 glnH Escherichia coli CFT073 glutamine ABC transporter periplasmic protein NP_752826.1 869609 R 199310 CDS NP_752827.1 26246787 1037880 complement(870282..870473) 1 NC_004431.1 hypothetical protein 870473 1037880 c0897 Escherichia coli CFT073 hypothetical protein NP_752827.1 870282 R 199310 CDS NP_752828.2 161486272 1037923 complement(870759..871262) 1 NC_004431.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 871262 dps 1037923 dps Escherichia coli CFT073 DNA starvation/stationary phase protection protein Dps NP_752828.2 870759 R 199310 CDS NP_752829.1 26246789 1039968 complement(871563..872462) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0813; Escherichia coli O157:H7 ortholog: z1035; threonine and homoserine efflux system 872462 ybiF 1039968 ybiF Escherichia coli CFT073 threonine and homoserine efflux system NP_752829.1 871563 R 199310 CDS NP_752830.1 26246790 1037896 872797..873318 1 NC_004431.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 873318 ompX 1037896 ompX Escherichia coli CFT073 outer membrane protein X NP_752830.1 872797 D 199310 CDS NP_752831.1 26246791 1037891 complement(873368..874951) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0815; Escherichia coli O157:H7 ortholog: z1037; hypothetical protein 874951 ybiP 1037891 ybiP Escherichia coli CFT073 hypothetical protein NP_752831.1 873368 R 199310 CDS NP_752832.1 26246792 1037900 complement(875223..875351) 1 NC_004431.1 hypothetical protein 875351 1037900 c0902 Escherichia coli CFT073 hypothetical protein NP_752832.1 875223 R 199310 CDS NP_752833.1 26246793 1037887 875537..876004 1 NC_004431.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 876004 1037887 c0903 Escherichia coli CFT073 manganese transport regulator MntR NP_752833.1 875537 D 199310 CDS NP_752834.1 26246794 1037938 876001..877119 1 NC_004431.1 Escherichia coli K-12 ortholog: b0818; Escherichia coli O157:H7 ortholog: z1040; hypothetical protein 877119 ybiR 1037938 ybiR Escherichia coli CFT073 hypothetical protein NP_752834.1 876001 D 199310 CDS NP_752835.1 26246795 1037947 complement(877177..878097) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0819; Escherichia coli O157:H7 ortholog: z1041; hypothetical protein 878097 ybiS 1037947 ybiS Escherichia coli CFT073 hypothetical protein NP_752835.1 877177 R 199310 CDS NP_752836.1 26246796 1037954 878316..879908 1 NC_004431.1 Escherichia coli K-12 ortholog: b0820; Escherichia coli O157:H7 ortholog: z1042; ABC transporter ATP-binding protein 879908 ybiT 1037954 ybiT Escherichia coli CFT073 ABC transporter ATP-binding protein NP_752836.1 878316 D 199310 CDS NP_752837.1 26246797 1039970 complement(880108..880923) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0822; Escherichia coli O157:H7 ortholog: z1044; hypothetical protein 880923 ybiV 1039970 ybiV Escherichia coli CFT073 hypothetical protein NP_752837.1 880108 R 199310 CDS NP_752838.1 26246798 1037922 complement(881069..883501) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0823; Escherichia coli O157:H7 ortholog: z1045; formate acetyltransferase 3 883501 ybiW 1037922 ybiW Escherichia coli CFT073 formate acetyltransferase 3 NP_752838.1 881069 R 199310 CDS NP_752839.1 26246799 1037979 complement(883507..884433) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0824; Escherichia coli O157:H7 ortholog: z1047; pyruvate formate-lyase 3 activating enzyme 884433 1037979 c0909 Escherichia coli CFT073 pyruvate formate-lyase 3 activating enzyme NP_752839.1 883507 R 199310 CDS NP_752840.2 161486271 1037976 884537..885199 1 NC_004431.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 885199 mipB 1037976 mipB Escherichia coli CFT073 fructose-6-phosphate aldolase NP_752840.2 884537 D 199310 CDS NP_752841.1 26246801 1035793 complement(885275..886024) 1 NC_004431.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 886024 moeB 1035793 moeB Escherichia coli CFT073 molybdopterin biosynthesis protein MoeB NP_752841.1 885275 R 199310 CDS NP_752842.1 26246802 1038013 complement(886024..887259) 1 NC_004431.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 887259 moeA 1038013 moeA Escherichia coli CFT073 molybdopterin biosynthesis protein MoeA NP_752842.1 886024 R 199310 CDS NP_752843.1 26246803 1035820 887463..888428 1 NC_004431.1 Escherichia coli K-12 ortholog: b0828; Escherichia coli O157:H7 ortholog: z1052; L-asparaginase 888428 ybiK 1035820 ybiK Escherichia coli CFT073 L-asparaginase NP_752843.1 887463 D 199310 CDS NP_752844.1 26246804 1037970 888397..890286 1 NC_004431.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 890286 yliA 1037970 yliA Escherichia coli CFT073 glutathione transporter ATP-binding protein NP_752844.1 888397 D 199310 CDS NP_752845.1 26246805 1037986 890150..891844 1 NC_004431.1 Escherichia coli K-12 ortholog: b0830; Escherichia coli O157:H7 ortholog: z1054; binding protein yliB 891844 1037986 c0915 Escherichia coli CFT073 binding protein yliB NP_752845.1 890150 D 199310 CDS NP_752846.1 26246806 1037991 891862..892782 1 NC_004431.1 Escherichia coli K-12 ortholog: b0831; Escherichia coli O157:H7 ortholog: z1055; ABC transporter permease 892782 yliC 1037991 yliC Escherichia coli CFT073 ABC transporter permease NP_752846.1 891862 D 199310 CDS NP_752847.1 26246807 1037977 892785..893696 1 NC_004431.1 Escherichia coli K-12 ortholog: b0832; Escherichia coli O157:H7 ortholog: z1056; ABC transporter permease 893696 yliD 1037977 yliD Escherichia coli CFT073 ABC transporter permease NP_752847.1 892785 D 199310 CDS NP_752848.1 26246808 1037993 893873..896221 1 NC_004431.1 Escherichia coli K-12 ortholog: b0833; Escherichia coli O157:H7 ortholog: z1057; hypothetical protein 896221 yliE 1037993 yliE Escherichia coli CFT073 hypothetical protein NP_752848.1 893873 D 199310 CDS NP_752849.1 26246809 1036723 896229..897557 1 NC_004431.1 Escherichia coli K-12 ortholog: b0834; Escherichia coli O157:H7 ortholog: z1058; membrane protein yliF 897557 yliF 1036723 yliF Escherichia coli CFT073 membrane protein yliF NP_752849.1 896229 D 199310 CDS NP_752850.1 26246810 1037995 complement(897604..898929) 1 NC_004431.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 898929 rimO 1037995 rimO Escherichia coli CFT073 ribosomal protein S12 methylthiotransferase NP_752850.1 897604 R 199310 CDS NP_752851.2 161486270 1038056 899142..899525 1 NC_004431.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 899525 bssR 1038056 bssR Escherichia coli CFT073 biofilm formation regulatory protein BssR NP_752851.2 899142 D 199310 CDS NP_752852.1 26246812 1038001 899636..900751 1 NC_004431.1 Escherichia coli K-12 ortholog: b0837; Escherichia coli O157:H7 ortholog: z1063; hypothetical protein 900751 yliI 1038001 yliI Escherichia coli CFT073 hypothetical protein NP_752852.1 899636 D 199310 CDS NP_752853.1 26246813 1038015 complement(900748..901380) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0838; Escherichia coli O157:H7 ortholog: z1064; GST-like protein yliJ 901380 yliJ 1038015 yliJ Escherichia coli CFT073 GST-like protein yliJ NP_752853.1 900748 R 199310 CDS NP_752854.1 26246814 1038062 901600..902823 1 NC_004431.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 902823 dacC 1038062 dacC Escherichia coli CFT073 D-alanyl-D-alanine carboxypeptidase fraction C NP_752854.1 901600 D 199310 CDS NP_752855.1 26246815 1037990 complement(902870..903628) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0840; Escherichia coli O157:H7 ortholog: z1067; DNA-binding transcriptional repressor DeoR 903628 deoR 1037990 deoR Escherichia coli CFT073 DNA-binding transcriptional repressor DeoR NP_752855.1 902870 R 199310 CDS NP_752856.1 26246816 1039972 complement(903686..904282) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0841; Escherichia coli O157:H7 ortholog: z1068; undecaprenyl pyrophosphate phosphatase 904282 ybjG 1039972 ybjG Escherichia coli CFT073 undecaprenyl pyrophosphate phosphatase NP_752856.1 903686 R 199310 CDS NP_752857.1 26246817 1038021 904537..905799 1 NC_004431.1 Chloramphenicol resistance pump cmr; Escherichia coli K-12 ortholog: b0842; Escherichia coli O157:H7 ortholog: z1069; multidrug translocase mdfA 905799 cmr 1038021 cmr Escherichia coli CFT073 multidrug translocase mdfA NP_752857.1 904537 D 199310 CDS NP_752858.1 26246818 1038074 complement(905840..906124) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0843; Escherichia coli O157:H7 ortholog: z1070; hypothetical protein 906124 ybjH 1038074 ybjH Escherichia coli CFT073 hypothetical protein NP_752858.1 905840 R 199310 CDS NP_752859.1 26246819 1038014 complement(906210..907028) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0844; Escherichia coli O157:H7 ortholog: z1071; hypothetical protein 907028 1038014 c0929 Escherichia coli CFT073 hypothetical protein NP_752859.1 906210 R 199310 CDS NP_752860.1 26246820 1036747 complement(907025..908296) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0845; Escherichia coli O157:H7 ortholog: z1072; hypothetical protein 908296 ybjJ 1036747 ybjJ Escherichia coli CFT073 hypothetical protein NP_752860.1 907025 R 199310 CDS NP_752861.1 26246821 1038055 908287..908853 1 NC_004431.1 Escherichia coli K-12 ortholog: b0846; Escherichia coli O157:H7 ortholog: z1073; hypothetical protein 908853 ybjK 1038055 ybjK Escherichia coli CFT073 hypothetical protein NP_752861.1 908287 D 199310 CDS NP_752862.1 26246822 1038068 complement(909332..910363) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2966; integrase for prophage 910363 intT 1038068 intT Escherichia coli CFT073 integrase for prophage NP_752862.1 909332 R 199310 CDS NP_752863.1 26246823 1035786 complement(910450..911421) 1 NC_004431.1 hypothetical protein 911421 1035786 c0933 Escherichia coli CFT073 hypothetical protein NP_752863.1 910450 R 199310 CDS NP_752864.1 26246824 1038070 complement(911434..912360) 1 NC_004431.1 Residues 114 to 307 of 308 are 47.42 pct identical to residues 5 to 198 of 198 from SwissProt.40 : >sp|P21323|YR7I_ECOLI HYPOTHETICAL 21.9 KD PROTEIN (ORFI) (RETRON EC67); hypothetical protein 912360 1038070 c0934 Escherichia coli CFT073 hypothetical protein NP_752864.1 911434 R 199310 CDS NP_752865.1 26246825 1038063 912449..912670 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2970; regulator for prophage 912670 coxT 1038063 coxT Escherichia coli CFT073 regulator for prophage NP_752865.1 912449 D 199310 CDS NP_752866.1 26246826 1039982 912649..913212 1 NC_004431.1 Residues 19 to 187 of 187 are 99.40 pct identical to residues 1 to 169 of 169 from SwissProt.40 : >sp|P21316|YR7B_ECOLI HYPOTHETICAL 18.1 KD PROTEIN (ORFB) (RETRON EC67); hypothetical protein 913212 1039982 c0936 Escherichia coli CFT073 hypothetical protein NP_752866.1 912649 D 199310 CDS NP_752867.1 26246827 1038133 913190..913420 1 NC_004431.1 Residues 11 to 60 of 76 are 81.99 pct identical to residues 1 to 50 of 75 from SwissProt.40 : >sp|P15236|VFIL_BP186 FIL PROTEIN; hypothetical protein 913420 1038133 c0937 Escherichia coli CFT073 hypothetical protein NP_752867.1 913190 D 199310 CDS NP_752868.1 26246828 1038096 913522..913725 1 NC_004431.1 Residues 1 to 67 of 67 are 100.00 pct identical to residues 47 to 113 of 113 from GenPept.129 : >emb|CAD09425.1| (AL627279) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 913725 1038096 c0938 Escherichia coli CFT073 hypothetical protein NP_752868.1 913522 D 199310 CDS NP_752869.1 26246829 1038115 913787..914026 1 NC_004431.1 Residues 9 to 79 of 79 are 46.47 pct identical to residues 7 to 77 of 77 from SwissProt.40 : >sp|P21682|CP79_BP186 Hypothetical 8.8 kDa protein in GPA 5'region; hypothetical protein 914026 1038115 c0939 Escherichia coli CFT073 hypothetical protein NP_752869.1 913787 D 199310 CDS NP_752870.1 26246830 1038089 914038..914253 1 NC_004431.1 Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024; hypothetical protein 914253 1038089 c0940 Escherichia coli CFT073 hypothetical protein NP_752870.1 914038 D 199310 CDS NP_752871.1 26246831 1038112 914250..915107 1 NC_004431.1 Escherichia coli K-12 ortholog: b3387; Escherichia coli O157:H7 ortholog: z4740; DNA adenine methylase 915107 1038112 c0941 Escherichia coli CFT073 DNA adenine methylase NP_752871.1 914250 D 199310 CDS NP_752872.1 26246832 1038292 915104..917518 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2978; replication protein for prophage 917518 1038292 c0942 Escherichia coli CFT073 replication protein for prophage NP_752872.1 915104 D 199310 CDS NP_752873.1 26246833 1038160 917799..918104 1 NC_004431.1 Residues 25 to 101 of 101 are 98.70 pct identical to residues 1 to 77 of 77 from SwissProt.40 : >sp|P21320|DIIR_ECOLI DinI-like protein in Retron EC67; hypothetical protein 918104 1038160 c0943 Escherichia coli CFT073 hypothetical protein NP_752873.1 917799 D 199310 CDS NP_752874.1 26246834 1038190 918325..918525 1 NC_004431.1 hypothetical protein 918525 1038190 c0944 Escherichia coli CFT073 hypothetical protein NP_752874.1 918325 D 199310 CDS NP_752875.1 26246835 1038286 918529..919311 1 NC_004431.1 hypothetical protein 919311 1038286 c0945 Escherichia coli CFT073 hypothetical protein NP_752875.1 918529 D 199310 CDS NP_752876.1 26246836 1035785 919531..920685 1 NC_004431.1 Residues 28 to 104 of 384 are 36.36 pct identical to residues 154 to 230 of 266 from GenPept.129 : >gb|AAB91582.2| (AF242881) ymh [Agrobacterium tumefaciens]; hypothetical protein 920685 1035785 c0946 Escherichia coli CFT073 hypothetical protein NP_752876.1 919531 D 199310 CDS NP_752877.1 26246837 1038303 complement(920737..921774) 1 NC_004431.1 Residues 2 to 300 of 345 are 96.98 pct identical to residues 1 to 299 of 326 from SwissProt.40 : >sp|P21314|YR75_ECOLI HYPOTHETICAL 36.8 KD PROTEIN (ORF5) (RETRON EC67); capsid portal protein 921774 1038303 c0947 Escherichia coli CFT073 capsid portal protein NP_752877.1 920737 R 199310 CDS NP_752878.1 26246838 1036751 complement(921771..923537) 1 NC_004431.1 Residues 3 to 588 of 588 are 63.38 pct identical to residues 4 to 590 of 590 from SwissProt.40 : >sp|P25479|VPP_BPP2 TERMINASE, ATPASE SUBUNIT (GPP); terminase, ATPase subunit 923537 1036751 c0948 Escherichia coli CFT073 terminase, ATPase subunit NP_752878.1 921771 R 199310 CDS NP_752879.1 26246839 1035373 complement(923547..923708) 1 NC_004431.1 hypothetical protein 923708 1035373 c0949 Escherichia coli CFT073 hypothetical protein NP_752879.1 923547 R 199310 CDS NP_752880.1 26246840 1038287 923686..924513 1 NC_004431.1 Residues 3 to 275 of 275 are 46.42 pct identical to residues 6 to 284 of 284 from SwissProt.40 : >sp|P25478|VPO_BPP2 PRESUMED CAPSID SCAFFOLDING PROTEIN (GPO); capsid scaffolding protein 924513 1038287 c0950 Escherichia coli CFT073 capsid scaffolding protein NP_752880.1 923686 D 199310 CDS NP_752881.1 26246841 1039978 complement(924410..925702) 1 NC_004431.1 hypothetical protein 925702 1039978 c0951 Escherichia coli CFT073 hypothetical protein NP_752881.1 924410 R 199310 CDS NP_752882.1 26246842 1038309 924530..925588 1 NC_004431.1 Residues 1 to 352 of 352 are 58.82 pct identical to residues 1 to 357 of 357 from SwissProt.40 : >sp|P25477|VPN_BPP2 MAJOR CAPSID PROTEIN PRECURSOR (GPN); major capsid protein 925588 1038309 c0952 Escherichia coli CFT073 major capsid protein NP_752882.1 924530 D 199310 CDS NP_752883.1 26246843 1038315 925691..926242 1 NC_004431.1 Residues 1 to 179 of 183 are 49.72 pct identical to residues 34 to 214 of 247 from SwissProt.40 : >sp|P25476|VPM_BPP2 TERMINASE, ENDONUCLEASE SUBUNIT (GPM); terminase, endonuclease subunit 926242 1038315 c0953 Escherichia coli CFT073 terminase, endonuclease subunit NP_752883.1 925691 D 199310 CDS NP_752884.1 26246844 1038218 926275..926802 1 NC_004431.1 Residues 1 to 175 of 175 are 98.28 pct identical to residues 1 to 175 of 175 from GenPept.129 : >emb|CAD09440.1| (AL627279) capsid completion protein [Salmonella enterica subsp. enterica serovar Typhi]; capsid completion protein 926802 1038218 c0954 Escherichia coli CFT073 capsid completion protein NP_752884.1 926275 D 199310 CDS NP_752885.1 26246845 1035784 926802..927005 1 NC_004431.1 Residues 1 to 67 of 67 are 61.19 pct identical to residues 1 to 67 of 67 from SwissProt.40 : >sp|P51772|VPX_BPP2 TAIL PROTEIN X (GPX); phage tail protein 927005 1035784 c0955 Escherichia coli CFT073 phage tail protein NP_752885.1 926802 D 199310 CDS NP_752886.1 26246846 1038343 927009..927224 1 NC_004431.1 Residues 1 to 71 of 71 are 98.59 pct identical to residues 1 to 71 of 71 from GenPept.129 : >emb|CAD09442.1| (AL627279) possible secretory protein [Salmonella enterica subsp. enterica serovar Typhi]; secretory protein 927224 1038343 c0956 Escherichia coli CFT073 secretory protein NP_752886.1 927009 D 199310 CDS NP_752887.1 26246847 1038294 927205..927717 1 NC_004431.1 Residues 1 to 168 of 170 are 91.66 pct identical to residues 1 to 168 of 169 from GenPept.129 : >gb|AAL21602.1| (AE008823) Fels-2 prophage: probable prophage lysozyme [Salmonella typhimurium LT2]; Fels-2 prophage: prophage lysozyme 927717 1038294 c0957 Escherichia coli CFT073 Fels-2 prophage: prophage lysozyme NP_752887.1 927205 D 199310 CDS NP_752888.1 26246848 1038301 927677..928096 1 NC_004431.1 Residues 15 to 139 of 139 are 98.40 pct identical to residues 1 to 125 of 125 from GenPept.129 : >emb|CAD09444.1| (AL627279) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 928096 1038301 c0958 Escherichia coli CFT073 hypothetical protein NP_752888.1 927677 D 199310 CDS NP_752889.1 26246849 1039980 928093..928521 1 NC_004431.1 Residues 1 to 142 of 142 are 95.07 pct identical to residues 1 to 142 of 142 from GenPept.129 : >emb|CAD09445.1| (AL627279) regulatory protein [Salmonella enterica subsp. enterica serovar Typhi]; regulatory protein 928521 1039980 c0959 Escherichia coli CFT073 regulatory protein NP_752889.1 928093 D 199310 CDS NP_752890.1 26246850 1038328 928596..929048 1 NC_004431.1 Residues 10 to 142 of 150 are 50.37 pct identical to residues 3 to 135 of 155 from SwissProt.40 : >sp|P36933|VPR_BPP2 TAIL COMPLETION PROTEIN R (GPR); phage tail protein 929048 1038328 c0960 Escherichia coli CFT073 phage tail protein NP_752890.1 928596 D 199310 CDS NP_752891.1 26246851 1038330 complement(928963..929520) 1 NC_004431.1 hypothetical protein 929520 1038330 c0961 Escherichia coli CFT073 hypothetical protein NP_752891.1 928963 R 199310 CDS NP_752892.1 26246852 1038342 929041..929487 1 NC_004431.1 Residues 1 to 148 of 148 are 98.64 pct identical to residues 1 to 148 of 148 from GenPept.129 : >emb|CAD09447.1| (AL627279) phage tail protein [Salmonella enterica subsp. enterica serovar Typhi]; phage tail protein 929487 1038342 c0962 Escherichia coli CFT073 phage tail protein NP_752892.1 929041 D 199310 CDS NP_752893.1 26246853 1038354 929556..930134 1 NC_004431.1 Residues 3 to 192 of 192 are 40.19 pct identical to residues 5 to 211 of 211 from SwissProt.40 : >sp|P31340|VPV_BPP2 BASEPLATE ASSEMBLY PROTEIN V (GPV); Phage baseplate assembly protein 930134 1038354 c0963 Escherichia coli CFT073 Phage baseplate assembly protein NP_752893.1 929556 D 199310 CDS NP_752894.1 26246854 1038367 930131..930490 1 NC_004431.1 Residues 4 to 110 of 119 are 53.70 pct identical to residues 5 to 112 of 115 from SwissProt.40 : >sp|P51768|VPW_BPP2 BASEPLATE ASSEMBLY PROTEIN W (GPW); Phage baseplate assembly protein 930490 1038367 c0964 Escherichia coli CFT073 Phage baseplate assembly protein NP_752894.1 930131 D 199310 CDS NP_752895.1 26246855 1038360 930477..931385 1 NC_004431.1 Residues 1 to 302 of 302 are 65.89 pct identical to residues 1 to 302 of 302 from SwissProt.40 : >sp|P51767|VPJ_BPP2 BASEPLATE ASSEMBLY PROTEIN J (GPJ); Phage baseplate assembly protein 931385 1038360 c0965 Escherichia coli CFT073 Phage baseplate assembly protein NP_752895.1 930477 D 199310 CDS NP_752896.1 26246856 1038356 931378..931983 1 NC_004431.1 Residues 4 to 173 of 201 are 57.05 pct identical to residues 6 to 175 of 176 from SwissProt.40 : >sp|P26701|VPI_BPP2 TAIL PROTEIN I (GPI); phage tail protein 931983 1038356 c0966 Escherichia coli CFT073 phage tail protein NP_752896.1 931378 D 199310 CDS NP_752897.1 26246857 1036757 complement(931408..931989) 1 NC_004431.1 hypothetical protein 931989 1036757 c0967 Escherichia coli CFT073 hypothetical protein NP_752897.1 931408 R 199310 CDS NP_752898.1 26246858 1038355 931980..933419 1 NC_004431.1 Residues 1 to 353 of 479 are 96.03 pct identical to residues 1 to 353 of 504 from GenPept.129 : >emb|CAD09452.1| (AL627279) probable variable tail fibre protein [Salmonella enterica subsp. enterica serovar Typhi]; variable tail fiber protein 933419 1038355 c0968 Escherichia coli CFT073 variable tail fiber protein NP_752898.1 931980 D 199310 CDS NP_752899.1 26246859 1038348 933422..933898 1 NC_004431.1 Escherichia coli K-12 ortholog: b2354; hypothetical protein 933898 yfdK 1038348 yfdK Escherichia coli CFT073 hypothetical protein NP_752899.1 933422 D 199310 CDS NP_752900.1 26246860 1038402 complement(933882..934913) 1 NC_004431.1 Residues 2 to 297 of 343 are 26.87 pct identical to residues 5 to 301 of 401 from GenPept.129 : >emb|CAC07472.1| (AX009415) product = eps11 [Lactobacillus helveticus]; hypothetical protein 934913 1038402 c0970 Escherichia coli CFT073 hypothetical protein NP_752900.1 933882 R 199310 CDS NP_752901.1 26246861 1038398 935127..936299 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2991; major tail sheath protein 936299 1038398 c0971 Escherichia coli CFT073 major tail sheath protein NP_752901.1 935127 D 199310 CDS NP_752902.1 26246862 1038390 936309..936824 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2990; tail fiber component of prophage 936824 1038390 c0972 Escherichia coli CFT073 tail fiber component of prophage NP_752902.1 936309 D 199310 CDS NP_752903.1 26246863 1038427 complement(936327..936911) 1 NC_004431.1 hypothetical protein 936911 1038427 c0973 Escherichia coli CFT073 hypothetical protein NP_752903.1 936327 R 199310 CDS NP_752904.1 26246864 1038413 936879..937181 1 NC_004431.1 Residues 1 to 100 of 100 are 99.00 pct identical to residues 1 to 100 of 100 from GenPept.129 : >emb|CAD09459.1| (AL627279) phage tail protein [Salmonella enterica subsp. enterica serovar Typhi]; phage tail protein 937181 1038413 c0974 Escherichia coli CFT073 phage tail protein NP_752904.1 936879 D 199310 CDS NP_752905.1 26246865 1038374 complement(936908..937363) 1 NC_004431.1 hypothetical protein 937363 1038374 c0975 Escherichia coli CFT073 hypothetical protein NP_752905.1 936908 R 199310 CDS NP_752906.1 26246866 1038411 937542..940385 1 NC_004431.1 Residues 1 to 947 of 947 are 97.67 pct identical to residues 79 to 1025 of 1025 from GenPept.129 : >emb|CAD09461.1| (AL627279) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 940385 1038411 c0976 Escherichia coli CFT073 hypothetical protein NP_752906.1 937542 D 199310 CDS NP_752907.1 26246867 1038394 940382..940867 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2985; tail fiber protein of prophage 940867 1038394 c0977 Escherichia coli CFT073 tail fiber protein of prophage NP_752907.1 940382 D 199310 CDS NP_752908.1 26246868 1035781 940864..941964 1 NC_004431.1 Residues 15 to 364 of 366 are 56.52 pct identical to residues 15 to 381 of 389 from SwissProt.40 : >sp|P21679|VPD_BP186 LATE CONTROL GENE D PROTEIN (GPD); regulator of late gene expression 941964 1035781 c0978 Escherichia coli CFT073 regulator of late gene expression NP_752908.1 940864 D 199310 CDS NP_752909.1 26246869 1038434 942022..942273 1 NC_004431.1 Escherichia coli K-12 ortholog: b2082; prophage P2 Ogr protein 942273 ogrK 1038434 ogrK Escherichia coli CFT073 prophage P2 Ogr protein NP_752909.1 942022 D 199310 CDS NP_752910.1 26246870 1035782 complement(942509..944194) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0847; Escherichia coli O157:H7 ortholog: z1074; hypothetical protein 944194 ybjL 1035782 ybjL Escherichia coli CFT073 hypothetical protein NP_752910.1 942509 R 199310 CDS NP_752911.1 26246871 1038432 944464..944841 1 NC_004431.1 Escherichia coli K-12 ortholog: b0848; Escherichia coli O157:H7 ortholog: z1075; hypothetical protein 944841 ybjM 1038432 ybjM Escherichia coli CFT073 hypothetical protein NP_752911.1 944464 D 199310 CDS NP_752912.2 161486269 1038384 complement(944871..945128) 1 NC_004431.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 945128 grxA 1038384 grxA Escherichia coli CFT073 glutaredoxin 1 NP_752912.2 944871 R 199310 CDS NP_752913.1 26246873 1038452 945288..945575 1 NC_004431.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 945575 ybjC 1038452 ybjC Escherichia coli CFT073 hypothetical protein NP_752913.1 945288 D 199310 CDS NP_752914.1 26246874 1038385 945559..946281 1 NC_004431.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 946281 mdaA 1038385 mdaA Escherichia coli CFT073 nitroreductase A NP_752914.1 945559 D 199310 CDS NP_752915.1 26246875 1035783 946342..947244 1 NC_004431.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 947244 rimK 1035783 rimK Escherichia coli CFT073 ribosomal protein S6 modification protein NP_752915.1 946342 D 199310 CDS NP_752916.1 26246876 1038391 947284..947808 1 NC_004431.1 Escherichia coli K-12 ortholog: b0853; Escherichia coli O157:H7 ortholog: z1080; hypothetical protein 947808 ybjN 1038391 ybjN Escherichia coli CFT073 hypothetical protein NP_752916.1 947284 D 199310 CDS NP_752917.1 26246877 1038465 948013..949269 1 NC_004431.1 Escherichia coli K-12 ortholog: b0854; Escherichia coli O157:H7 ortholog: z1081; putrescine transporter subunit: periplasmic-binding component of ABC superfamily 949269 potF 1038465 potF Escherichia coli CFT073 putrescine transporter subunit: periplasmic-binding component of ABC superfamily NP_752917.1 948013 D 199310 CDS NP_752918.2 161486268 1038426 949364..950497 1 NC_004431.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 950497 potG 1038426 potG Escherichia coli CFT073 putrescine transporter ATP-binding subunit NP_752918.2 949364 D 199310 CDS NP_752919.1 26246879 1038425 950507..951451 1 NC_004431.1 Escherichia coli K-12 ortholog: b0856; Escherichia coli O157:H7 ortholog: z1083; putrescine transporter subunit: membrane component of ABC superfamily 951451 potH 1038425 potH Escherichia coli CFT073 putrescine transporter subunit: membrane component of ABC superfamily NP_752919.1 950507 D 199310 CDS NP_752920.1 26246880 1040158 951406..952293 1 NC_004431.1 Escherichia coli K-12 ortholog: b0857; Escherichia coli O157:H7 ortholog: z1084; putrescine transporter subunit: membrane component of ABC superfamily 952293 potI 1040158 potI Escherichia coli CFT073 putrescine transporter subunit: membrane component of ABC superfamily NP_752920.1 951406 D 199310 CDS NP_752921.1 26246881 1035780 952353..952841 1 NC_004431.1 Escherichia coli K-12 ortholog: b0858; Escherichia coli O157:H7 ortholog: z1085; hypothetical protein 952841 ybjO 1035780 ybjO Escherichia coli CFT073 hypothetical protein NP_752921.1 952353 D 199310 CDS NP_752922.1 26246882 1036761 952882..954009 1 NC_004431.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 954009 rumB 1036761 rumB Escherichia coli CFT073 23S rRNA methyluridine methyltransferase NP_752922.1 952882 D 199310 CDS NP_752923.1 26246883 1038468 complement(954038..954820) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0860; Escherichia coli O157:H7 ortholog: z1090; arginine-binding periplasmic protein 2 954820 artJ 1038468 artJ Escherichia coli CFT073 arginine-binding periplasmic protein 2 NP_752923.1 954038 R 199310 CDS NP_752924.1 26246884 1038458 complement(954995..955663) 1 NC_004431.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 955663 artM 1038458 artM Escherichia coli CFT073 arginine transporter permease subunit ArtM NP_752924.1 954995 R 199310 CDS NP_752925.1 26246885 1038501 complement(955663..956379) 1 NC_004431.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 956379 artQ 1038501 artQ Escherichia coli CFT073 arginine transporter permease subunit ArtQ NP_752925.1 955663 R 199310 CDS NP_752926.1 26246886 1038479 complement(956386..957117) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0863; Escherichia coli O157:H7 ortholog: z1093; arginine-binding periplasmic protein 1 957117 artI 1038479 artI Escherichia coli CFT073 arginine-binding periplasmic protein 1 NP_752926.1 956386 R 199310 CDS NP_752927.2 161486267 1038444 complement(957135..957863) 1 NC_004431.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 957863 artP 1038444 artP Escherichia coli CFT073 arginine transporter ATP-binding subunit NP_752927.2 957135 R 199310 CDS NP_752928.1 26246888 1035653 complement(958081..958620) 1 NC_004431.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 958620 ybjP 1035653 ybjP Escherichia coli CFT073 lipoprotein NP_752928.1 958081 R 199310 CDS NP_752929.1 26246889 1038521 958722..959045 1 NC_004431.1 Escherichia coli K-12 ortholog: b0866; Escherichia coli O157:H7 ortholog: z1099; hypothetical protein 959045 ybjQ 1038521 ybjQ Escherichia coli CFT073 hypothetical protein NP_752929.1 958722 D 199310 CDS NP_752930.1 26246890 1038522 959042..959872 1 NC_004431.1 Escherichia coli K-12 ortholog: b0867; Escherichia coli O157:H7 ortholog: z1100; N-acetylmuramoyl-L-alanine amidase 959872 ybjR 1038522 ybjR Escherichia coli CFT073 N-acetylmuramoyl-L-alanine amidase NP_752930.1 959042 D 199310 CDS NP_752931.1 26246891 1036763 complement(959869..960945) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0868; Escherichia coli O157:H7 ortholog: z1102; hypothetical protein 960945 1036763 c1001 Escherichia coli CFT073 hypothetical protein NP_752931.1 959869 R 199310 CDS NP_752932.1 26246892 1038497 complement(960981..962486) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0869; Escherichia coli O157:H7 ortholog: z1103; hypothetical protein 962486 ybjT 1038497 ybjT Escherichia coli CFT073 hypothetical protein NP_752932.1 960981 R 199310 CDS NP_752933.1 26246893 1038542 complement(962422..963423) 1 NC_004431.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 963423 ybjU 1038542 ybjU Escherichia coli CFT073 L-threonine aldolase NP_752933.1 962422 R 199310 CDS NP_752934.1 26246894 1038558 complement(963460..965178) 1 NC_004431.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 965178 poxB 1038558 poxB Escherichia coli CFT073 pyruvate dehydrogenase NP_752934.1 963460 R 199310 CDS NP_752935.1 26246895 1036765 complement(965311..966285) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0872; Escherichia coli O157:H7 ortholog: z1106; HCP oxidoreductase, NADH-dependent 966285 1036765 c1005 Escherichia coli CFT073 HCP oxidoreductase, NADH-dependent NP_752935.1 965311 R 199310 CDS NP_752936.2 161486266 1038506 complement(966291..967943) 1 NC_004431.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 967943 ybjW 1038506 ybjW Escherichia coli CFT073 hydroxylamine reductase NP_752936.2 966291 R 199310 CDS NP_752937.1 26246897 1038535 complement(968087..968986) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0874; Escherichia coli O157:H7 ortholog: z1108; hypothetical protein 968986 ybjE 1038535 ybjE Escherichia coli CFT073 hypothetical protein NP_752937.1 968087 R 199310 CDS NP_752938.1 26246898 1038546 968964..969098 1 NC_004431.1 hypothetical protein 969098 1038546 c1008 Escherichia coli CFT073 hypothetical protein NP_752938.1 968964 D 199310 CDS NP_752939.1 26246899 1038573 complement(969480..970181) 1 NC_004431.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 970181 aqpZ 1038573 aqpZ Escherichia coli CFT073 aquaporin Z NP_752939.1 969480 R 199310 CDS NP_752940.1 26246900 1035779 complement(970388..970543) 1 NC_004431.1 hypothetical protein 970543 1035779 c1010 Escherichia coli CFT073 hypothetical protein NP_752940.1 970388 R 199310 CDS NP_752941.1 26246901 1036768 970601..972259 1 NC_004431.1 Escherichia coli K-12 ortholog: b0876; Escherichia coli O157:H7 ortholog: z1110; hypothetical protein 972259 ybjD 1036768 ybjD Escherichia coli CFT073 hypothetical protein NP_752941.1 970601 D 199310 CDS NP_752942.1 26246902 1035773 complement(972256..973248) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0877; Escherichia coli O157:H7 ortholog: z1112; hypothetical protein 973248 ybjX 1035773 ybjX Escherichia coli CFT073 hypothetical protein NP_752942.1 972256 R 199310 CDS NP_752943.1 26246903 1038528 973317..973451 1 NC_004431.1 Residues 1 to 44 of 44 are 93.18 pct identical to residues 1 to 44 of 44 from GenPept.129 : >dbj|BAA35596.1| (D90725) ORF_ID:o213#2 [Escherichia coli]; hypothetical protein 973451 1038528 c1013 Escherichia coli CFT073 hypothetical protein NP_752943.1 973317 D 199310 CDS NP_752944.2 161486265 1038502 973363..974478 1 NC_004431.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 974478 macA 1038502 macA Escherichia coli CFT073 macrolide transporter subunit MacA NP_752944.2 973363 D 199310 CDS NP_752945.1 26246905 1038537 976078..976422 1 NC_004431.1 Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein 976422 1038537 c1016 Escherichia coli CFT073 hypothetical protein NP_752945.1 976078 D 199310 CDS NP_752946.1 26246906 1035774 complement(976495..976749) 1 NC_004431.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 976749 cspD 1035774 cspD Escherichia coli CFT073 stationary phase/starvation inducible regulatory protein CspD NP_752946.1 976495 R 199310 CDS NP_752947.1 26246907 1038534 977042..977362 1 NC_004431.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 977362 clpS 1038534 clpS Escherichia coli CFT073 ATP-dependent Clp protease adaptor protein ClpS NP_752947.1 977042 D 199310 CDS NP_752948.2 161486264 1038589 977393..979669 1 NC_004431.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 979669 clpA 1038589 clpA Escherichia coli CFT073 ATP-dependent Clp protease ATP-binding subunit NP_752948.2 977393 D 199310 CDS YP_004853799.1 347357908 1038552 complement(979726..980118) 1 NC_004431.1 hypothetical protein 980118 1038552 c1020 Escherichia coli CFT073 hypothetical protein YP_004853799.1 979726 R 199310 CDS NP_752950.1 26246910 1035770 complement(980354..980572) 1 NC_004431.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 980572 infA 1035770 infA Escherichia coli CFT073 translation initiation factor IF-1 NP_752950.1 980354 R 199310 CDS NP_752951.1 26246911 1038609 complement(980857..981561) 1 NC_004431.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 981561 aat 1038609 aat Escherichia coli CFT073 leucyl/phenylalanyl-tRNA--protein transferase NP_752951.1 980857 R 199310 CDS NP_752952.1 26246912 1038571 complement(981603..983324) 1 NC_004431.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 983324 cydC 1038571 cydC Escherichia coli CFT073 cysteine/glutathione ABC transporter membrane/ATP-binding component NP_752952.1 981603 R 199310 CDS NP_752953.1 26246913 1038606 complement(983325..985091) 1 NC_004431.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 985091 cydD 1038606 cydD Escherichia coli CFT073 cysteine/glutathione ABC transporter membrane/ATP-binding component NP_752953.1 983325 R 199310 CDS NP_752954.1 26246914 1038595 complement(985214..986299) 1 NC_004431.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 986299 trxB 1038595 trxB Escherichia coli CFT073 thioredoxin reductase NP_752954.1 985214 R 199310 CDS NP_752955.2 161486263 1038629 986723..987217 1 NC_004431.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 987217 lrp 1038629 lrp Escherichia coli CFT073 leucine-responsive transcriptional regulator NP_752955.2 986723 D 199310 CDS NP_752956.1 26246916 1038631 987352..991395 1 NC_004431.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 991395 ftsK 1038631 ftsK Escherichia coli CFT073 DNA translocase FtsK NP_752956.1 987352 D 199310 CDS NP_752957.1 26246917 1039991 991551..992165 1 NC_004431.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 992165 lolA 1039991 lolA Escherichia coli CFT073 outer-membrane lipoprotein carrier protein NP_752957.1 991551 D 199310 CDS NP_752958.1 26246918 1038658 992176..993519 1 NC_004431.1 Escherichia coli K-12 ortholog: b0892; Escherichia coli O157:H7 ortholog: z1238; recombination factor protein RarA 993519 ycaJ 1038658 ycaJ Escherichia coli CFT073 recombination factor protein RarA NP_752958.1 992176 D 199310 CDS NP_752959.1 26246919 1036773 993610..994902 1 NC_004431.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 994902 serS 1036773 serS Escherichia coli CFT073 seryl-tRNA synthetase NP_752959.1 993610 D 199310 CDS NP_752960.1 26246920 1038617 995141..997585 1 NC_004431.1 Escherichia coli K-12 ortholog: b0894; Escherichia coli O157:H7 ortholog: z1240; anaerobic dimethyl sulfoxide reductase chain A 997585 dmsA 1038617 dmsA Escherichia coli CFT073 anaerobic dimethyl sulfoxide reductase chain A NP_752960.1 995141 D 199310 CDS NP_752961.1 26246921 1038639 997596..998213 1 NC_004431.1 DMSO reductase iron-sulfur subunit; Escherichia coli K-12 ortholog: b0895; Escherichia coli O157:H7 ortholog: z1241; anaerobic dimethyl sulfoxide reductase chain B 998213 dmsB 1038639 dmsB Escherichia coli CFT073 anaerobic dimethyl sulfoxide reductase chain B NP_752961.1 997596 D 199310 CDS NP_752962.1 26246922 1038623 998215..999078 1 NC_004431.1 DMSO reductase anchor subunit; Escherichia coli K-12 ortholog: b0896; Escherichia coli O157:H7 ortholog: z1242; anaerobic dimethyl sulfoxide reductase chain C 999078 dmsC 1038623 dmsC Escherichia coli CFT073 anaerobic dimethyl sulfoxide reductase chain C NP_752962.1 998215 D 199310 CDS NP_752963.1 26246923 1036774 complement(999114..999839) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0897; Escherichia coli O157:H7 ortholog: z1243; hypothetical protein 999839 ycaC 1036774 ycaC Escherichia coli CFT073 hypothetical protein NP_752963.1 999114 R 199310 CDS NP_752964.1 26246924 1038651 complement(999895..1000023) 1 NC_004431.1 hypothetical protein 1000023 1038651 c1035 Escherichia coli CFT073 hypothetical protein NP_752964.1 999895 R 199310 CDS NP_752965.1 26246925 1038648 999971..1000108 1 NC_004431.1 hypothetical protein 1000108 1038648 c1036 Escherichia coli CFT073 hypothetical protein NP_752965.1 999971 D 199310 CDS NP_752966.1 26246926 1038692 1000054..1001202 1 NC_004431.1 ORF Y; Escherichia coli K-12 ortholog: b0898; Escherichia coli O157:H7 ortholog: z1244; MFS family transporter protein 1001202 ycaD 1038692 ycaD Escherichia coli CFT073 MFS family transporter protein NP_752966.1 1000054 D 199310 CDS NP_752967.2 161486262 1038676 complement(1001299..1002039) 1 NC_004431.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1002039 pflA 1038676 pflA Escherichia coli CFT073 pyruvate formate lyase-activating enzyme 1 NP_752967.2 1001299 R 199310 CDS NP_752968.1 26246928 1038678 1003279..1004493 1 NC_004431.1 hypothetical protein 1004493 1038678 c1040 Escherichia coli CFT073 hypothetical protein NP_752968.1 1003279 D 199310 CDS NP_752969.1 26246929 1038659 complement(1004569..1005765) 1 NC_004431.1 Formate channel 1; Escherichia coli K-12 ortholog: b0904; Escherichia coli O157:H7 ortholog: z1250; formate transporter 1005765 focA_2 1038659 focA_2 Escherichia coli CFT073 formate transporter NP_752969.1 1004569 R 199310 CDS NP_752970.1 26246930 1036777 complement(1005832..1007625) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0905; Escherichia coli O157:H7 ortholog: z1251; hypothetical protein 1007625 ycaO 1036777 ycaO Escherichia coli CFT073 hypothetical protein NP_752970.1 1005832 R 199310 CDS NP_752971.1 26246931 1035768 1007722..1008414 1 NC_004431.1 Escherichia coli K-12 ortholog: b0906; Escherichia coli O157:H7 ortholog: z1252; hypothetical protein 1008414 ycaP 1035768 ycaP Escherichia coli CFT073 hypothetical protein NP_752971.1 1007722 D 199310 CDS NP_752972.1 26246932 1039994 1008613..1009701 1 NC_004431.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1009701 serC 1039994 serC Escherichia coli CFT073 phosphoserine aminotransferase NP_752972.1 1008613 D 199310 CDS NP_752973.1 26246933 1035769 1009772..1011055 1 NC_004431.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1011055 aroA 1035769 aroA Escherichia coli CFT073 3-phosphoshikimate 1-carboxyvinyltransferase NP_752973.1 1009772 D 199310 CDS NP_752974.1 26246934 1038735 1011216..1011989 1 NC_004431.1 Escherichia coli K-12 ortholog: b0909; Escherichia coli O157:H7 ortholog: z1255; metalloprotease ycaL 1011989 ycaL 1038735 ycaL Escherichia coli CFT073 metalloprotease ycaL NP_752974.1 1011216 D 199310 CDS NP_752975.1 26246935 1038671 1012162..1012845 1 NC_004431.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1012845 cmk 1038671 cmk Escherichia coli CFT073 cytidylate kinase NP_752975.1 1012162 D 199310 CDS NP_752976.1 26246936 1038789 1012956..1014629 1 NC_004431.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1014629 rpsA 1038789 rpsA Escherichia coli CFT073 30S ribosomal protein S1 NP_752976.1 1012956 D 199310 CDS NP_752977.1 26246937 1038705 1014789..1015073 1 NC_004431.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1015073 ihfB 1038705 ihfB Escherichia coli CFT073 integration host factor subunit beta NP_752977.1 1014789 D 199310 CDS NP_752978.1 26246938 1038020 complement(1014798..1015106) 1 NC_004431.1 hypothetical protein 1015106 1038020 c1051 Escherichia coli CFT073 hypothetical protein NP_752978.1 1014798 R 199310 CDS NP_752979.2 161486261 1038691 1015279..1017543 1 NC_004431.1 Escherichia coli K-12 ortholog: b0913; Escherichia coli O157:H7 ortholog: z1259; hypothetical protein 1017543 ycaI 1038691 ycaI Escherichia coli CFT073 hypothetical protein NP_752979.2 1015279 D 199310 CDS YP_004853800.1 347357924 1038772 1016634..1016768 1 NC_004431.1 hypothetical protein 1016768 1038772 c1053 Escherichia coli CFT073 hypothetical protein YP_004853800.1 1016634 D 199310 CDS NP_752981.1 26246941 1038715 1017580..1019328 1 NC_004431.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1019328 msbA 1038715 msbA Escherichia coli CFT073 lipid transporter ATP-binding/permease NP_752981.1 1017580 D 199310 CDS NP_752982.1 26246942 1036780 1020349..1021581 1 NC_004431.1 Escherichia coli K-12 ortholog: b0916; Escherichia coli O157:H7 ortholog: z1262; hypothetical protein 1021581 ycaQ 1036780 ycaQ Escherichia coli CFT073 hypothetical protein NP_752982.1 1020349 D 199310 CDS NP_752983.1 26246943 1038719 1021633..1021815 1 NC_004431.1 Escherichia coli K-12 ortholog: b0917; Escherichia coli O157:H7 ortholog: z1263; hypothetical protein 1021815 ycaR 1038719 ycaR Escherichia coli CFT073 hypothetical protein NP_752983.1 1021633 D 199310 CDS NP_752984.1 26246944 1038778 1021812..1022558 1 NC_004431.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1022558 kdsB 1038778 kdsB Escherichia coli CFT073 3-deoxy-manno-octulosonate cytidylyltransferase NP_752984.1 1021812 D 199310 CDS NP_752985.1 26246945 1038766 1022712..1023605 1 NC_004431.1 Escherichia coli K-12 ortholog: b0919; Escherichia coli O157:H7 ortholog: z1265; hypothetical protein 1023605 ycbJ 1038766 ycbJ Escherichia coli CFT073 hypothetical protein NP_752985.1 1022712 D 199310 CDS NP_752986.1 26246946 1038770 complement(1023582..1024361) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0920; Escherichia coli O157:H7 ortholog: z1267; hypothetical protein 1024361 ycbC 1038770 ycbC Escherichia coli CFT073 hypothetical protein NP_752986.1 1023582 R 199310 CDS NP_752987.1 26246947 1038818 complement(1024264..1024428) 1 NC_004431.1 hypothetical protein 1024428 1038818 c1062 Escherichia coli CFT073 hypothetical protein NP_752987.1 1024264 R 199310 CDS NP_752988.1 26246948 1038811 1024485..1025282 1 NC_004431.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1025282 smtA 1038811 smtA Escherichia coli CFT073 metallothionein SmtA NP_752988.1 1024485 D 199310 CDS NP_752989.1 26246949 1038835 1025279..1026601 1 NC_004431.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1026601 mukF 1038835 mukF Escherichia coli CFT073 condesin subunit F NP_752989.1 1025279 D 199310 CDS NP_752990.1 26246950 1038800 1026555..1027286 1 NC_004431.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1027286 mukE 1038800 mukE Escherichia coli CFT073 condesin subunit E NP_752990.1 1026555 D 199310 CDS NP_752991.1 26246951 1038807 1027286..1031746 1 NC_004431.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1031746 mukB 1038807 mukB Escherichia coli CFT073 cell division protein MukB NP_752991.1 1027286 D 199310 CDS NP_752992.1 26246952 1038825 1032007..1033854 1 NC_004431.1 Escherichia coli K-12 ortholog: b0925; Escherichia coli O157:H7 ortholog: z1272; hypothetical protein 1033854 ycbB 1038825 ycbB Escherichia coli CFT073 hypothetical protein NP_752992.1 1032007 D 199310 CDS NP_752993.1 26246953 1038827 1034026..1034583 1 NC_004431.1 Escherichia coli K-12 ortholog: b0926; Escherichia coli O157:H7 ortholog: z1273; hypothetical protein 1034583 ycbK 1038827 ycbK Escherichia coli CFT073 hypothetical protein NP_752993.1 1034026 D 199310 CDS NP_752994.1 26246954 1038823 1034610..1035257 1 NC_004431.1 Escherichia coli K-12 ortholog: b0927; Escherichia coli O157:H7 ortholog: z1274; hypothetical protein 1035257 ycbL 1038823 ycbL Escherichia coli CFT073 hypothetical protein NP_752994.1 1034610 D 199310 CDS NP_752995.1 26246955 1038848 complement(1035307..1036497) 1 NC_004431.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1036497 aspC 1038848 aspC Escherichia coli CFT073 aromatic amino acid aminotransferase NP_752995.1 1035307 R 199310 CDS NP_752996.1 26246956 1038831 complement(1036682..1037770) 1 NC_004431.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1037770 ompF 1038831 ompF Escherichia coli CFT073 outer membrane protein F NP_752996.1 1036682 R 199310 CDS NP_752997.1 26246957 1036783 complement(1038373..1039773) 1 NC_004431.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1039773 asnC 1036783 asnC Escherichia coli CFT073 asparaginyl-tRNA synthetase NP_752997.1 1038373 R 199310 CDS NP_752998.1 26246958 1038812 complement(1039942..1041192) 1 NC_004431.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1041192 pncB 1038812 pncB Escherichia coli CFT073 nicotinate phosphoribosyltransferase NP_752998.1 1039942 R 199310 CDS NP_752999.1 26246959 1038840 1039960..1040145 1 NC_004431.1 hypothetical protein 1040145 1038840 c1074 Escherichia coli CFT073 hypothetical protein NP_752999.1 1039960 D 199310 CDS NP_753000.1 26246960 1035766 1041410..1044022 1 NC_004431.1 Escherichia coli K-12 ortholog: b0932; Escherichia coli O157:H7 ortholog: z1280; aminopeptidase 1044022 pepN 1035766 pepN Escherichia coli CFT073 aminopeptidase NP_753000.1 1041410 D 199310 CDS NP_753001.1 26246961 1038887 complement(1044217..1044984) 1 NC_004431.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1044984 ssuB 1038887 ssuB Escherichia coli CFT073 aliphatic sulfonates transport ATP-binding subunit NP_753001.1 1044217 R 199310 CDS NP_753002.1 26246962 1035762 complement(1044981..1045775) 1 NC_004431.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit 1045775 ssuC 1035762 ssuC Escherichia coli CFT073 alkanesulfonate transporter permease subunit NP_753002.1 1044981 R 199310 CDS NP_753003.1 26246963 1038862 complement(1045784..1046929) 1 NC_004431.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1046929 ycbN 1038862 ycbN Escherichia coli CFT073 alkanesulfonate monooxygenase NP_753003.1 1045784 R 199310 CDS NP_753004.2 161486260 1038819 complement(1046926..1047885) 1 NC_004431.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1047885 ycbO 1038819 ycbO Escherichia coli CFT073 alkanesulfonate transporter substrate-binding subunit NP_753004.2 1046926 R 199310 CDS NP_753005.1 26246965 1038901 complement(1047878..1048453) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0937; Escherichia coli O157:H7 ortholog: z1285; NAD(P)H-dependent FMN reductase 1048453 ycbP 1038901 ycbP Escherichia coli CFT073 NAD(P)H-dependent FMN reductase NP_753005.1 1047878 R 199310 CDS NP_753006.1 26246966 1039998 1048663..1049700 1 NC_004431.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1049700 pyrD 1039998 pyrD Escherichia coli CFT073 dihydroorotate dehydrogenase 2 NP_753006.1 1048663 D 199310 CDS NP_753007.1 26246967 1035764 1049838..1050416 1 NC_004431.1 Escherichia coli K-12 ortholog: b0946; Escherichia coli O157:H7 ortholog: z1295; hypothetical protein 1050416 ycbW 1035764 ycbW Escherichia coli CFT073 hypothetical protein NP_753007.1 1049838 D 199310 CDS NP_753008.1 26246968 1038837 complement(1050413..1051522) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0947; Escherichia coli O157:H7 ortholog: z1297; hypothetical protein 1051522 ycbX 1038837 ycbX Escherichia coli CFT073 hypothetical protein NP_753008.1 1050413 R 199310 CDS NP_753009.1 26246969 1038883 1051620..1053728 1 NC_004431.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1053728 rlmL 1038883 rlmL Escherichia coli CFT073 23S rRNA m(2)G2445 methyltransferase NP_753009.1 1051620 D 199310 CDS NP_753010.1 26246970 1038871 1053740..1055647 1 NC_004431.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase component 1055647 uup 1038871 uup Escherichia coli CFT073 ABC transporter ATPase component NP_753010.1 1053740 D 199310 CDS NP_753011.1 26246971 1035761 1055777..1057030 1 NC_004431.1 Escherichia coli K-12 ortholog: b0950; Escherichia coli O157:H7 ortholog: z1300; paraquat-inducible protein A 1057030 pqiA 1035761 pqiA Escherichia coli CFT073 paraquat-inducible protein A NP_753011.1 1055777 D 199310 CDS NP_753012.1 26246972 1038905 1056975..1058675 1 NC_004431.1 Escherichia coli K-12 ortholog: b0951; Escherichia coli O157:H7 ortholog: z1301; paraquat-inducible protein B 1058675 pqiB 1038905 pqiB Escherichia coli CFT073 paraquat-inducible protein B NP_753012.1 1056975 D 199310 CDS NP_753013.1 26246973 1038912 1058672..1059235 1 NC_004431.1 Escherichia coli K-12 ortholog: b0952; Escherichia coli O157:H7 ortholog: z1302; hypothetical protein 1059235 ymbA 1038912 ymbA Escherichia coli CFT073 hypothetical protein NP_753013.1 1058672 D 199310 CDS NP_753014.1 26246974 1038894 complement(1059400..1059531) 1 NC_004431.1 hypothetical protein 1059531 1038894 c1089 Escherichia coli CFT073 hypothetical protein NP_753014.1 1059400 R 199310 CDS NP_753015.2 161486259 1038890 complement(1059727..1060245) 1 NC_004431.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1060245 fabA 1038890 fabA Escherichia coli CFT073 3-hydroxydecanoyl-ACP dehydratase NP_753015.2 1059727 R 199310 CDS NP_753016.1 26246976 1038931 complement(1060314..1062074) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0955; Escherichia coli O157:H7 ortholog: z1305; protease La-like protein 1062074 1038931 c1091 Escherichia coli CFT073 protease La-like protein NP_753016.1 1060314 R 199310 CDS NP_753017.1 26246977 1038947 1062260..1062712 1 NC_004431.1 Escherichia coli K-12 ortholog: b0956; Escherichia coli O157:H7 ortholog: z1306; hypothetical protein 1062712 ycbG 1038947 ycbG Escherichia coli CFT073 hypothetical protein NP_753017.1 1062260 D 199310 CDS NP_753018.1 26246978 1039999 complement(1062790..1063929) 1 NC_004431.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1063929 ompA 1039999 ompA Escherichia coli CFT073 outer membrane protein A NP_753018.1 1062790 R 199310 CDS NP_753019.1 26246979 1036798 1063996..1064214 1 NC_004431.1 hypothetical protein 1064214 1036798 c1094 Escherichia coli CFT073 hypothetical protein NP_753019.1 1063996 D 199310 CDS NP_753020.1 26246980 1038951 complement(1064198..1064713) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0958; Escherichia coli O157:H7 ortholog: z1308; SOS cell division inhibitor 1064713 sulA 1038951 sulA Escherichia coli CFT073 SOS cell division inhibitor NP_753020.1 1064198 R 199310 CDS NP_753021.1 26246981 1038964 1064926..1065555 1 NC_004431.1 Escherichia coli K-12 ortholog: b0959; Escherichia coli O157:H7 ortholog: z1309; hypothetical protein 1065555 yccR 1038964 yccR Escherichia coli CFT073 hypothetical protein NP_753021.1 1064926 D 199310 CDS NP_753022.1 26246982 1038952 complement(1065518..1067680) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0960; Escherichia coli O157:H7 ortholog: z1311; hypothetical protein 1067680 yccS 1038952 yccS Escherichia coli CFT073 hypothetical protein NP_753022.1 1065518 R 199310 CDS NP_753023.1 26246983 1038934 complement(1067690..1068136) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0961; Escherichia coli O157:H7 ortholog: z1312; hypothetical protein 1068136 yccF 1038934 yccF Escherichia coli CFT073 hypothetical protein NP_753023.1 1067690 R 199310 CDS NP_753024.2 161486258 1038988 1068259..1070313 1 NC_004431.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1070313 helD 1038988 helD Escherichia coli CFT073 DNA helicase IV NP_753024.2 1068259 D 199310 CDS NP_753025.2 161486257 1038977 complement(1070345..1070803) 1 NC_004431.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1070803 mgsA 1038977 mgsA Escherichia coli CFT073 methylglyoxal synthase NP_753025.2 1070345 R 199310 CDS NP_753026.1 26246986 1038991 complement(1070899..1071561) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0964; Escherichia coli O157:H7 ortholog: z1315; hypothetical protein 1071561 yccT 1038991 yccT Escherichia coli CFT073 hypothetical protein NP_753026.1 1070899 R 199310 CDS NP_753027.1 26246987 1038965 1071653..1072147 1 NC_004431.1 Escherichia coli K-12 ortholog: b0965; Escherichia coli O157:H7 ortholog: z1317; hypothetical protein 1072147 1038965 c1102 Escherichia coli CFT073 hypothetical protein NP_753027.1 1071653 D 199310 CDS NP_753028.1 26246988 1035759 1072116..1072511 1 NC_004431.1 hypothetical protein 1072511 1035759 c1103 Escherichia coli CFT073 hypothetical protein NP_753028.1 1072116 D 199310 CDS NP_753029.1 26246989 1039016 complement(1072192..1072560) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0966; Escherichia coli O157:H7 ortholog: z1318; heat shock protein HspQ 1072560 yccV 1039016 yccV Escherichia coli CFT073 heat shock protein HspQ NP_753029.1 1072192 R 199310 CDS NP_753030.1 26246990 1035760 complement(1072567..1073757) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0967; Escherichia coli O157:H7 ortholog: z1319; hypothetical protein 1073757 yccW 1035760 yccW Escherichia coli CFT073 hypothetical protein NP_753030.1 1072567 R 199310 CDS NP_753031.1 26246991 1039010 1073732..1074130 1 NC_004431.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1074130 1039010 c1106 Escherichia coli CFT073 acylphosphatase NP_753031.1 1073732 D 199310 CDS NP_753032.1 26246992 1038946 complement(1074127..1074456) 1 NC_004431.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1074456 yccK 1038946 yccK Escherichia coli CFT073 sulfur transfer protein TusE NP_753032.1 1074127 R 199310 CDS YP_004853801.1 347357925 1039031 1074172..1074474 1 NC_004431.1 hypothetical protein 1074474 1039031 c1108 Escherichia coli CFT073 hypothetical protein YP_004853801.1 1074172 D 199310 CDS YP_004853802.1 347357926 1038980 1074542..1075186 1 NC_004431.1 hypothetical protein 1075186 1038980 c1109 Escherichia coli CFT073 hypothetical protein YP_004853802.1 1074542 D 199310 CDS NP_753035.1 26246995 1035757 complement(1074548..1075207) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0970; Escherichia coli O157:H7 ortholog: z1322; hypothetical protein 1075207 yccA 1035757 yccA Escherichia coli CFT073 hypothetical protein NP_753035.1 1074548 R 199310 CDS YP_004853803.1 347357909 1039007 complement(1075409..1075585) 1 NC_004431.1 hypothetical protein 1075585 1039007 c1111 Escherichia coli CFT073 hypothetical protein YP_004853803.1 1075409 R 199310 CDS NP_753037.1 26246997 1038996 complement(1075769..1075909) 1 NC_004431.1 hypothetical protein 1075909 1038996 c1112 Escherichia coli CFT073 hypothetical protein NP_753037.1 1075769 R 199310 CDS NP_753038.1 26246998 1040006 1075901..1077046 1 NC_004431.1 Escherichia coli K-12 ortholog: b0972; Escherichia coli O157:H7 ortholog: z1389; hydrogenase-1 small chain 1077046 hyaA 1040006 hyaA Escherichia coli CFT073 hydrogenase-1 small chain NP_753038.1 1075901 D 199310 CDS NP_753039.1 26246999 1035758 1077043..1078836 1 NC_004431.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1078836 hyaB 1035758 hyaB Escherichia coli CFT073 hydrogenase 1 large subunit NP_753039.1 1077043 D 199310 CDS NP_753040.1 26247000 1036808 1078855..1079562 1 NC_004431.1 Escherichia coli K-12 ortholog: b0974; Escherichia coli O157:H7 ortholog: z1391; hydrogenase 1 b-type cytochrome subunit 1079562 hyaC 1036808 hyaC Escherichia coli CFT073 hydrogenase 1 b-type cytochrome subunit NP_753040.1 1078855 D 199310 CDS NP_753041.1 26247001 1039024 1079559..1080146 1 NC_004431.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1080146 hyaD 1039024 hyaD Escherichia coli CFT073 hydrogenase 1 maturation protease NP_753041.1 1079559 D 199310 CDS NP_753042.1 26247002 1039028 1080143..1080541 1 NC_004431.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1080541 hyaE 1039028 hyaE Escherichia coli CFT073 hydrogenase-1 operon protein HyaE NP_753042.1 1080143 D 199310 CDS NP_753043.1 26247003 1039059 1080538..1081395 1 NC_004431.1 Escherichia coli K-12 ortholog: b0977; Escherichia coli O157:H7 ortholog: z1394; hydrogenase-1 operon protein HyaF 1081395 hyaF 1039059 hyaF Escherichia coli CFT073 hydrogenase-1 operon protein HyaF NP_753043.1 1080538 D 199310 CDS NP_753044.1 26247004 1039033 1081529..1083073 1 NC_004431.1 Escherichia coli K-12 ortholog: b0978; Escherichia coli O157:H7 ortholog: z1395; cytochrome bd-II oxidase subunit I 1083073 appC 1039033 appC Escherichia coli CFT073 cytochrome bd-II oxidase subunit I NP_753044.1 1081529 D 199310 CDS NP_753045.1 26247005 1039056 1083085..1084221 1 NC_004431.1 Escherichia coli K-12 ortholog: b0979; Escherichia coli O157:H7 ortholog: z1396; cytochrome bd-II oxidase subunit II 1084221 appB 1039056 appB Escherichia coli CFT073 cytochrome bd-II oxidase subunit II NP_753045.1 1083085 D 199310 CDS NP_753046.1 26247006 1039047 1084376..1085716 1 NC_004431.1 Escherichia coli K-12 ortholog: b0980; Escherichia coli O157:H7 ortholog: z1397; bifunctional; phosphoanhydride phosphorylase 1085716 appA 1039047 appA Escherichia coli CFT073 phosphoanhydride phosphorylase NP_753046.1 1084376 D 199310 CDS NP_753047.1 26247007 1039038 complement(1085704..1085916) 1 NC_004431.1 CSP-H; Escherichia coli K-12 ortholog: b0989; Escherichia coli O157:H7 ortholog: z1405; cold shock-like protein cspH 1085916 cspH 1039038 cspH Escherichia coli CFT073 cold shock-like protein cspH NP_753047.1 1085704 R 199310 CDS NP_753048.1 26247008 1039086 1086202..1086414 1 NC_004431.1 CSP-G; Escherichia coli K-12 ortholog: b0990; Escherichia coli O157:H7 ortholog: z1406; cold shock protein CspG 1086414 cspG 1039086 cspG Escherichia coli CFT073 cold shock protein CspG NP_753048.1 1086202 D 199310 CDS NP_753049.1 26247009 1039036 1086555..1086818 1 NC_004431.1 Escherichia coli K-12 ortholog: b0991; Escherichia coli O157:H7 ortholog: z1408; cold shock gene 1086818 sfa 1039036 sfa Escherichia coli CFT073 cold shock gene NP_753049.1 1086555 D 199310 CDS NP_753050.1 26247010 1040007 1086808..1086981 1 NC_004431.1 Escherichia coli K-12 ortholog: b1550; GnsB protein 1086981 1040007 c1125 Escherichia coli CFT073 GnsB protein NP_753050.1 1086808 D 199310 CDS NP_753051.1 26247011 1039123 complement(1086823..1086996) 1 NC_004431.1 hypothetical protein 1086996 1039123 c1126 Escherichia coli CFT073 hypothetical protein NP_753051.1 1086823 R 199310 CDS NP_753052.1 26247012 1036811 complement(1087030..1088103) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0992; Escherichia coli O157:H7 ortholog: z1409; electron transport protein yccM 1088103 yccM 1036811 yccM Escherichia coli CFT073 electron transport protein yccM NP_753052.1 1087030 R 199310 CDS NP_753053.2 161486256 1039114 complement(1088186..1090918) 1 NC_004431.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1090918 torS 1039114 torS Escherichia coli CFT073 hybrid sensory histidine kinase TorS NP_753053.2 1088186 R 199310 CDS YP_004853804.1 347357910 1039065 complement(1090698..1090967) 1 NC_004431.1 hypothetical protein 1090967 1039065 c1129 Escherichia coli CFT073 hypothetical protein YP_004853804.1 1090698 R 199310 CDS NP_753055.1 26247015 1039138 1091001..1092029 1 NC_004431.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1092029 torT 1039138 torT Escherichia coli CFT073 TMAO reductase system periplasmic protein TorT NP_753055.1 1091001 D 199310 CDS NP_753056.1 26247016 1039104 complement(1092002..1092694) 1 NC_004431.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1092694 torR 1039104 torR Escherichia coli CFT073 DNA-binding transcriptional regulator TorR NP_753056.1 1092002 R 199310 CDS NP_753057.1 26247017 1039281 1092776..1093996 1 NC_004431.1 Escherichia coli K-12 ortholog: b0996; Escherichia coli O157:H7 ortholog: z1414; cytochrome c-type protein torC 1093996 torC 1039281 torC Escherichia coli CFT073 cytochrome c-type protein torC NP_753057.1 1092776 D 199310 CDS NP_753058.1 26247018 1039106 1093996..1096542 1 NC_004431.1 Escherichia coli K-12 ortholog: b0997; Escherichia coli O157:H7 ortholog: z1415; trimethylamine-N-oxide reductase 1 1096542 torA 1039106 torA Escherichia coli CFT073 trimethylamine-N-oxide reductase 1 NP_753058.1 1093996 D 199310 CDS NP_753059.2 161486255 1039357 1096539..1097138 1 NC_004431.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1097138 torD 1039357 torD Escherichia coli CFT073 chaperone protein TorD NP_753059.2 1096539 D 199310 CDS NP_753060.1 26247020 1039103 complement(1097494..1097799) 1 NC_004431.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1097799 yccD 1039103 yccD Escherichia coli CFT073 chaperone-modulator protein CbpM NP_753060.1 1097494 R 199310 CDS NP_753061.1 26247021 1039135 complement(1097799..1098719) 1 NC_004431.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1098719 cbpA 1039135 cbpA Escherichia coli CFT073 curved DNA-binding protein CbpA NP_753061.1 1097799 R 199310 CDS NP_753062.1 26247022 1035752 1099254..1100210 1 NC_004431.1 Escherichia coli K-12 ortholog: b1002; Escherichia coli O157:H7 ortholog: z1421; glucose-1-phosphatase/inositol phosphatase 1100210 agp 1035752 agp Escherichia coli CFT073 glucose-1-phosphatase/inositol phosphatase NP_753062.1 1099254 D 199310 CDS NP_753063.1 26247023 1039141 1100241..1100495 1 NC_004431.1 Residues 21 to 84 of 84 are 96.87 pct identical to residues 350 to 413 of 413 from GenPept.129 : >gb|AAG55550.1|AE005294_5 (AE005294) periplasmic glucose-1-phosphatase [Escherichia coli O157:H7 EDL933]; hypothetical protein 1100495 1039141 c1138 Escherichia coli CFT073 hypothetical protein NP_753063.1 1100241 D 199310 CDS NP_753064.1 26247024 1035751 complement(1100533..1100760) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1003; Escherichia coli O157:H7 ortholog: z1422; hypothetical protein 1100760 yccJ 1035751 yccJ Escherichia coli CFT073 hypothetical protein NP_753064.1 1100533 R 199310 CDS NP_753065.1 26247025 1039126 complement(1100781..1101377) 1 NC_004431.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1101377 wrbA 1039126 wrbA Escherichia coli CFT073 TrpR binding protein WrbA NP_753065.1 1100781 R 199310 CDS NP_753066.1 26247026 1039117 1101781..1101939 1 NC_004431.1 hypothetical protein 1101939 1039117 c1141 Escherichia coli CFT073 hypothetical protein NP_753066.1 1101781 D 199310 CDS NP_753067.1 26247027 1036820 1101936..1102073 1 NC_004431.1 hypothetical protein 1102073 1036820 c1142 Escherichia coli CFT073 hypothetical protein NP_753067.1 1101936 D 199310 CDS NP_753068.1 26247028 1039134 complement(1102006..1103400) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1006; Escherichia coli O157:H7 ortholog: z1505; purine permease ycdG 1103400 ycdG 1039134 ycdG Escherichia coli CFT073 purine permease ycdG NP_753068.1 1102006 R 199310 CDS NP_753069.1 26247029 1035755 complement(1103355..1103909) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1007; Escherichia coli O157:H7 ortholog: z1506; flavin:NADH reductase ycdH 1103909 1035755 c1144 Escherichia coli CFT073 flavin:NADH reductase ycdH NP_753069.1 1103355 R 199310 CDS NP_753070.1 26247030 1039177 complement(1103860..1104450) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1008; Escherichia coli O157:H7 ortholog: z1507; hypothetical protein 1104450 1039177 c1145 Escherichia coli CFT073 hypothetical protein NP_753070.1 1103860 R 199310 CDS NP_753071.3 347357898 1035754 complement(1104460..1105287) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1009; Escherichia coli O157:H7 ortholog: z1508; hypothetical protein 1105287 ycdJ 1035754 ycdJ Escherichia coli CFT073 hypothetical protein NP_753071.3 1104460 R 199310 CDS NP_753072.1 26247032 1039370 complement(1105268..1105654) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1010; Escherichia coli O157:H7 ortholog: z1509; hypothetical protein 1105654 ycdK 1039370 ycdK Escherichia coli CFT073 hypothetical protein NP_753072.1 1105268 R 199310 CDS NP_753073.1 26247033 1039352 complement(1105666..1106400) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1011; Escherichia coli O157:H7 ortholog: z1510; isochorismatase family protein ycdL 1106400 ycdL 1039352 ycdL Escherichia coli CFT073 isochorismatase family protein ycdL NP_753073.1 1105666 R 199310 CDS NP_753074.1 26247034 1039358 complement(1106358..1107539) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1012; Escherichia coli O157:H7 ortholog: z1511; monooxygenase ycdM 1107539 1039358 c1149 Escherichia coli CFT073 monooxygenase ycdM NP_753074.1 1106358 R 199310 CDS NP_753075.1 26247035 1039388 1107710..1108375 1 NC_004431.1 Escherichia coli K-12 ortholog: b1013; Escherichia coli O157:H7 ortholog: z1512; transcriptional regulator YcdC 1108375 ycdC 1039388 ycdC Escherichia coli CFT073 transcriptional regulator YcdC NP_753075.1 1107710 D 199310 CDS NP_753076.3 347357897 1040013 complement(1108415..1112443) 1 NC_004431.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1112443 putA 1040013 putA Escherichia coli CFT073 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase NP_753076.3 1108415 R 199310 CDS NP_753077.1 26247037 1039379 1112432..1112641 1 NC_004431.1 hypothetical protein 1112641 1039379 c1152 Escherichia coli CFT073 hypothetical protein NP_753077.1 1112432 D 199310 CDS NP_753078.1 26247038 1039412 complement(1112529..1112720) 1 NC_004431.1 Residues 1 to 63 of 63 are 100.00 pct identical to residues 1 to 63 of 111 from GenPept.129 : >emb|CAA29142.1| (X05653) ORF (AA 1-111) [Escherichia coli]; hypothetical protein 1112720 1039412 c1153 Escherichia coli CFT073 hypothetical protein NP_753078.1 1112529 R 199310 CDS NP_753079.1 26247039 1039423 1112800..1114308 1 NC_004431.1 Proline permease; Escherichia coli K-12 ortholog: b1015; Escherichia coli O157:H7 ortholog: z1515; Sodium/proline symporter 1114308 putP 1039423 putP Escherichia coli CFT073 Sodium/proline symporter NP_753079.1 1112800 D 199310 CDS NP_753080.1 26247040 1039415 1114592..1115359 1 NC_004431.1 Escherichia coli K-12 ortholog: b1017; Escherichia coli O157:H7 ortholog: z1519; cytochrome 1115359 1039415 c1155 Escherichia coli CFT073 cytochrome NP_753080.1 1114592 D 199310 CDS NP_753081.1 26247041 1036827 1115417..1116544 1 NC_004431.1 Escherichia coli K-12 ortholog: b1018; Escherichia coli O157:H7 ortholog: z1520; hypothetical protein 1116544 ycdO 1036827 ycdO Escherichia coli CFT073 hypothetical protein NP_753081.1 1115417 D 199310 CDS NP_753082.1 26247042 1039418 1116550..1117821 1 NC_004431.1 Escherichia coli K-12 ortholog: b1019; Escherichia coli O157:H7 ortholog: z1521; hypothetical protein 1117821 ycdB 1039418 ycdB Escherichia coli CFT073 hypothetical protein NP_753082.1 1116550 D 199310 CDS NP_753083.1 26247043 1039413 complement(1117958..1118092) 1 NC_004431.1 hypothetical protein 1118092 1039413 c1158 Escherichia coli CFT073 hypothetical protein NP_753083.1 1117958 R 199310 CDS NP_753084.1 26247044 1039402 1118312..1119235 1 NC_004431.1 Phosphate starvation-inducible protein psiH; Escherichia coli K-12 ortholog: b1020; Escherichia coli O157:H7 ortholog: z1522; hypothetical protein 1119235 phoH 1039402 phoH Escherichia coli CFT073 hypothetical protein NP_753084.1 1118312 D 199310 CDS NP_753085.1 26247045 1039447 complement(1119285..1119698) 1 NC_004431.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1119698 pgaD 1039447 pgaD Escherichia coli CFT073 PGA biosynthesis protein NP_753085.1 1119285 R 199310 CDS NP_753086.1 26247046 1039434 complement(1119700..1121025) 1 NC_004431.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1121025 ycdQ 1039434 ycdQ Escherichia coli CFT073 N-glycosyltransferase NP_753086.1 1119700 R 199310 CDS NP_753087.1 26247047 1039403 complement(1121018..1123036) 1 NC_004431.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1123036 pgaB 1039403 pgaB Escherichia coli CFT073 outer membrane N-deacetylase NP_753087.1 1121018 R 199310 CDS NP_753088.1 26247048 1039425 complement(1123045..1125468) 1 NC_004431.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1125468 pgaA 1039425 pgaA Escherichia coli CFT073 outer membrane protein PgaA NP_753088.1 1123045 R 199310 CDS NP_753089.1 26247049 1039416 1125933..1127423 1 NC_004431.1 Escherichia coli K-12 ortholog: b1025; Escherichia coli O157:H7 ortholog: z1527; hypothetical protein 1127423 ycdT 1039416 ycdT Escherichia coli CFT073 hypothetical protein NP_753089.1 1125933 D 199310 CDS NP_753090.1 26247050 1035745 1127702..1128904 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1559; P4 family integrase 1128904 1035745 c1165 Escherichia coli CFT073 P4 family integrase NP_753090.1 1127702 D 199310 CDS NP_753091.1 26247051 1039464 complement(1129092..1130909) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1560; hypothetical protein 1130909 1039464 c1166 Escherichia coli CFT073 hypothetical protein NP_753091.1 1129092 R 199310 CDS NP_753092.1 26247052 1035741 1131195..1131359 1 NC_004431.1 Residues 8 to 54 of 54 are 76.59 pct identical to residues 37 to 83 of 90 from GenPept.129 : >gb|AAL72381.1| (AF386526) INSA [Shigella flexneri 2a]; hypothetical protein 1131359 1035741 c1167 Escherichia coli CFT073 hypothetical protein NP_753092.1 1131195 D 199310 CDS NP_753093.1 26247053 1039414 1131407..1131799 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1562; hypothetical protein 1131799 1039414 c1168 Escherichia coli CFT073 hypothetical protein NP_753093.1 1131407 D 199310 CDS NP_753094.1 26247054 1039489 1132071..1132319 1 NC_004431.1 Escherichia coli K-12 ortholog: b2624; Escherichia coli O157:H7 ortholog: z1563; prophage CP4-57 regulatory protein alpA 1132319 alpA 1039489 alpA Escherichia coli CFT073 prophage CP4-57 regulatory protein alpA NP_753094.1 1132071 D 199310 CDS NP_753095.1 26247055 1039452 1132944..1134404 1 NC_004431.1 Escherichia coli K-12 ortholog: b2625; Escherichia coli O157:H7 ortholog: z1565; hypothetical protein 1134404 1039452 c1170 Escherichia coli CFT073 hypothetical protein NP_753095.1 1132944 D 199310 CDS NP_753096.1 26247056 1035750 1135368..1135961 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1567; hypothetical protein 1135961 1035750 c1171 Escherichia coli CFT073 hypothetical protein NP_753096.1 1135368 D 199310 CDS NP_753097.1 26247057 1039471 complement(1136060..1136317) 1 NC_004431.1 hypothetical protein 1136317 1039471 c1172 Escherichia coli CFT073 hypothetical protein NP_753097.1 1136060 R 199310 CDS NP_753098.1 26247058 1039497 1136063..1136269 1 NC_004431.1 Residues 19 to 68 of 68 are 83.99 pct identical to residues 204 to 253 of 287 from GenPept.129 : >gb|AAL22135.1| (AE008850) methyltransferase [Salmonella typhimurium LT2]; hypothetical protein 1136269 1039497 c1173 Escherichia coli CFT073 hypothetical protein NP_753098.1 1136063 D 199310 CDS NP_753099.1 26247059 1039456 complement(1136438..1138438) 1 NC_004431.1 Residues 89 to 661 of 666 are 54.87 pct identical to residues 54 to 622 of 636 from GenPept.129 : >gb|AAL73391.1|AF419157_1 (AF419157) enterotoxin [Aeromonas hydrophila]; hypothetical protein 1138438 1039456 c1174 Escherichia coli CFT073 hypothetical protein NP_753099.1 1136438 R 199310 CDS NP_753100.1 26247060 1039479 complement(1138353..1139519) 1 NC_004431.1 Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]; aminotransferase 1139519 1039479 c1175 Escherichia coli CFT073 aminotransferase NP_753100.1 1138353 R 199310 CDS NP_753101.1 26247061 1035749 complement(1139941..1140564) 1 NC_004431.1 Fusion of Escherichia coli K-12 B3132 and B3136; Residues 94 to 207 of 207 are 80.70 pct identical to residues 268 to 381 of 384 from GenPept.129 : >gb|AAC76170.1| (AE000395) tagatose-6-phosphate aldose/ketose isomerase [Escherichia coli K12]; hypothetical protein 1140564 1035749 c1176 Escherichia coli CFT073 hypothetical protein NP_753101.1 1139941 R 199310 CDS NP_753102.1 26247062 1039507 1142429..1142953 1 NC_004431.1 hypothetical protein 1142953 1039507 c1183 Escherichia coli CFT073 hypothetical protein NP_753102.1 1142429 D 199310 CDS NP_753103.1 26247063 1039499 1142992..1143417 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1634; hypothetical protein 1143417 1039499 c1184 Escherichia coli CFT073 hypothetical protein NP_753103.1 1142992 D 199310 CDS NP_753104.1 26247064 1039546 complement(1143016..1143180) 1 NC_004431.1 hypothetical protein 1143180 1039546 c1185 Escherichia coli CFT073 hypothetical protein NP_753104.1 1143016 R 199310 CDS NP_753105.1 26247065 1039543 complement(1143727..1144956) 1 NC_004431.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1144956 1039543 c1186 Escherichia coli CFT073 3-oxoacyl-ACP synthase NP_753105.1 1143727 R 199310 CDS NP_753106.1 26247066 1040314 complement(1144953..1145684) 1 NC_004431.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1145684 fabG 1040314 fabG Escherichia coli CFT073 3-ketoacyl-ACP reductase NP_753106.1 1144953 R 199310 CDS NP_753107.1 26247067 1036884 complement(1145684..1146148) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4864; hypothetical protein 1146148 1036884 c1188 Escherichia coli CFT073 hypothetical protein NP_753107.1 1145684 R 199310 CDS NP_753108.1 26247068 1040306 complement(1146145..1147323) 1 NC_004431.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1147323 1040306 c1189 Escherichia coli CFT073 3-oxoacyl-ACP synthase NP_753108.1 1146145 R 199310 CDS NP_753109.1 26247069 1040313 complement(1147316..1147900) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4862; hypothetical protein 1147900 1040313 c1190 Escherichia coli CFT073 hypothetical protein NP_753109.1 1147316 R 199310 CDS NP_753110.1 26247070 1035740 complement(1147897..1150215) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4861; hypothetical protein 1150215 1035740 c1191 Escherichia coli CFT073 hypothetical protein NP_753110.1 1147897 R 199310 CDS NP_753111.1 26247071 1040321 complement(1150184..1150789) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4860; hypothetical protein 1150789 1040321 c1192 Escherichia coli CFT073 hypothetical protein NP_753111.1 1150184 R 199310 CDS NP_753112.1 26247072 1040331 complement(1150786..1151208) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4859; hypothetical protein 1151208 1040331 c1193 Escherichia coli CFT073 hypothetical protein NP_753112.1 1150786 R 199310 CDS NP_753113.1 26247073 1035744 complement(1151212..1152834) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4858; hypothetical protein 1152834 1035744 c1194 Escherichia coli CFT073 hypothetical protein NP_753113.1 1151212 R 199310 CDS NP_753114.1 26247074 1040315 complement(1152806..1152928) 1 NC_004431.1 hypothetical protein 1152928 1040315 c1195 Escherichia coli CFT073 hypothetical protein NP_753114.1 1152806 R 199310 CDS NP_753115.1 26247075 1040327 complement(1152879..1153256) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4857; hypothetical protein 1153256 1040327 c1196 Escherichia coli CFT073 hypothetical protein NP_753115.1 1152879 R 199310 CDS NP_753116.1 26247076 1035743 complement(1153219..1154577) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4856; hypothetical protein 1154577 1035743 c1197 Escherichia coli CFT073 hypothetical protein NP_753116.1 1153219 R 199310 CDS NP_753117.1 26247077 1040302 complement(1154574..1155158) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4855; hypothetical protein 1155158 1040302 c1198 Escherichia coli CFT073 hypothetical protein NP_753117.1 1154574 R 199310 CDS NP_753118.1 26247078 1040364 complement(1155160..1155411) 1 NC_004431.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1155411 1040364 c1199 Escherichia coli CFT073 acyl carrier protein NP_753118.1 1155160 R 199310 CDS NP_753119.1 26247079 1039903 complement(1155423..1155680) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4853; acyl carrier protein 1155680 1039903 c1200 Escherichia coli CFT073 acyl carrier protein NP_753119.1 1155423 R 199310 CDS NP_753120.1 26247080 1040322 complement(1155655..1156494) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4852; phospholipid biosynthesis acyltransferase 1156494 1040322 c1201 Escherichia coli CFT073 phospholipid biosynthesis acyltransferase NP_753120.1 1155655 R 199310 CDS NP_753121.1 26247081 1040330 complement(1156473..1157219) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4851; hypothetical protein 1157219 1040330 c1202 Escherichia coli CFT073 hypothetical protein NP_753121.1 1156473 R 199310 CDS NP_753122.1 26247082 1035742 complement(1157236..1158294) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4850; O-methyltransferase 1158294 1035742 c1203 Escherichia coli CFT073 O-methyltransferase NP_753122.1 1157236 R 199310 CDS NP_753123.1 26247083 1040337 complement(1158359..1158748) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4849; hypothetical protein 1158748 1040337 c1204 Escherichia coli CFT073 hypothetical protein NP_753123.1 1158359 R 199310 CDS NP_753124.1 26247084 1040359 1159313..1162039 1 NC_004431.1 Residues 678 to 908 of 908 are 24.05 pct identical to residues 2464 to 2674 of 3535 from GenPept.129 : >gb|AAG03431.1|AE004443_9 (AE004443) probable hemagglutinin [Pseudomonas aeruginosa]; hypothetical protein 1162039 1040359 c1205 Escherichia coli CFT073 hypothetical protein NP_753124.1 1159313 D 199310 CDS NP_753125.1 26247085 1040325 1161999..1163231 1 NC_004431.1 Residues 8 to 375 of 410 are 24.61 pct identical to residues 1490 to 1839 of 2535 from GenPept.129 : >emb|CAC91295.1| (AJ414152) hemolysin [Yersinia pestis]; hypothetical protein 1163231 1040325 c1206 Escherichia coli CFT073 hypothetical protein NP_753125.1 1161999 D 199310 CDS NP_753126.1 26247086 1040356 1163191..1164804 1 NC_004431.1 Residues 13 to 409 of 537 are 50.72 pct identical to residues 1970 to 2381 of 2535 from GenPept.129 : >emb|CAC91295.1| (AJ414152) hemolysin [Yersinia pestis]; hypothetical protein 1164804 1040356 c1207 Escherichia coli CFT073 hypothetical protein NP_753126.1 1163191 D 199310 CDS NP_753127.1 26247087 1040381 1165325..1165702 1 NC_004431.1 Residues 3 to 121 of 125 are 57.14 pct identical to residues 3098 to 3216 of 3295 from GenPept.129 : >emb|CAC89456.1| (AJ414143) adhesin [Yersinia pestis]; hypothetical protein 1165702 1040381 c1208 Escherichia coli CFT073 hypothetical protein NP_753127.1 1165325 D 199310 CDS NP_753128.1 26247088 1040378 1166202..1166597 1 NC_004431.1 hypothetical protein 1166597 1040378 c1209 Escherichia coli CFT073 hypothetical protein NP_753128.1 1166202 D 199310 CDS NP_753129.1 26247089 1040346 complement(1166395..1166571) 1 NC_004431.1 hypothetical protein 1166571 1040346 c1210 Escherichia coli CFT073 hypothetical protein NP_753129.1 1166395 R 199310 CDS NP_753130.1 26247090 1040396 1167823..1168386 1 NC_004431.1 Residues 33 to 186 of 187 are 94.15 pct identical to residues 128 to 281 of 282 from GenPept.129 : >dbj|BAA75091.1| (AB021078) 61 pct identical to 126 residues of 138 aa protein sp:YTL1_SALTY[hypothetical 15.2kd protein near tlpA operon of S. typhimurium plasmid] [Plasmid ColIb-P9]; hypothetical protein 1168386 1040396 c1213 Escherichia coli CFT073 hypothetical protein NP_753130.1 1167823 D 199310 CDS NP_753131.1 26247091 1040400 complement(1168463..1168702) 1 NC_004431.1 Residues 1 to 72 of 79 are 94.44 pct identical to residues 1 to 72 of 521 from GenPept.129 : >gb|AAA98156.1| (M37218) cea gene product [Plasmid pKY1]; Cea protein 1168702 1040400 c1214 Escherichia coli CFT073 Cea protein NP_753131.1 1168463 R 199310 CDS NP_753132.1 26247092 1040405 1169460..1169669 1 NC_004431.1 Residues 1 to 68 of 69 are 97.05 pct identical to residues 69 to 136 of 139 from GenPept.129 : >gb|AAB59140.1| (J01566) entry exclusion protein 2 (exc2) [Plasmid ColE1]; entry exclusion protein 2 1169669 1040405 c1215 Escherichia coli CFT073 entry exclusion protein 2 NP_753132.1 1169460 D 199310 CDS NP_753133.1 26247093 1040380 complement(1169792..1169947) 1 NC_004431.1 Residues 14 to 51 of 51 are 71.42 pct identical to residues 272 to 313 of 313 from GenPept.129 : >gb|AAL23539.1| (AE006471) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 1169947 1040380 c1216 Escherichia coli CFT073 hypothetical protein NP_753133.1 1169792 R 199310 CDS NP_753134.1 26247094 1040373 complement(1169968..1170276) 1 NC_004431.1 hypothetical protein 1170276 1040373 c1217 Escherichia coli CFT073 hypothetical protein NP_753134.1 1169968 R 199310 CDS NP_753135.1 26247095 1037012 complement(1170358..1170861) 1 NC_004431.1 Residues 1 to 167 of 167 are 96.40 pct identical to residues 373 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 1170861 1037012 c1218 Escherichia coli CFT073 hypothetical protein NP_753135.1 1170358 R 199310 CDS NP_753136.1 26247096 1037060 complement(1170833..1171582) 1 NC_004431.1 Residues 1 to 237 of 249 are 96.20 pct identical to residues 133 to 369 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; transposase 1171582 1037060 c1219 Escherichia coli CFT073 transposase NP_753136.1 1170833 R 199310 CDS NP_753137.1 26247097 1037008 1172485..1173561 1 NC_004431.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose-4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1173561 1037008 c1220 Escherichia coli CFT073 phospho-2-dehydro-3-deoxyheptonate aldolase NP_753137.1 1172485 D 199310 CDS NP_753138.1 26247098 1037028 1173449..1173682 1 NC_004431.1 hypothetical protein 1173682 1037028 c1221 Escherichia coli CFT073 hypothetical protein NP_753138.1 1173449 D 199310 CDS NP_753139.1 26247099 1035737 1174032..1174163 1 NC_004431.1 hypothetical protein 1174163 1035737 c1222 Escherichia coli CFT073 hypothetical protein NP_753139.1 1174032 D 199310 CDS NP_753140.1 26247100 1035739 complement(1174628..1175380) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2089; Escherichia coli O157:H7 ortholog: z1573; transposase insF 1175380 1035739 c1224 Escherichia coli CFT073 transposase insF NP_753140.1 1174628 R 199310 CDS NP_753141.1 26247101 1040406 complement(1175364..1175588) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2088; transposase insE 1175588 1040406 c1225 Escherichia coli CFT073 transposase insE NP_753141.1 1175364 R 199310 CDS NP_753142.1 26247102 1039907 1176756..1177049 1 NC_004431.1 Possible fusion with mchI; Residues 23 to 97 of 97 are 100.00 pct identical to residues 1 to 75 of 75 from SwissProt.40 : >sp|Q9RM53|MCHB_ECOLI Microcin H47 precursor (MccH47); MchB protein 1177049 mchB 1039907 mchB Escherichia coli CFT073 MchB protein NP_753142.1 1176756 D 199310 CDS NP_753143.1 26247103 1040409 1177321..1178871 1 NC_004431.1 Residues 1 to 516 of 516 are 73.44 pct identical to residues 9 to 524 of 524 from GenPept.129 : >gb|AAL08403.1| (AF063590) MceJ [Klebsiella pneumoniae]; MchC protein 1178871 mchC 1040409 mchC Escherichia coli CFT073 MchC protein NP_753143.1 1177321 D 199310 CDS NP_753144.1 26247104 1036982 1178897..1179349 1 NC_004431.1 Residues 1 to 149 of 150 are 88.59 pct identical to residues 4 to 152 of 163 from GenPept.129 : >gb|AAL08402.1| (AF063590) MceI [Klebsiella pneumoniae]; MchD protein 1179349 mchD 1036982 mchD Escherichia coli CFT073 MchD protein NP_753144.1 1178897 D 199310 CDS NP_753145.1 26247105 1036922 1179502..1180776 1 NC_004431.1 Residues 1 to 424 of 424 are 98.82 pct identical to residues 1 to 424 of 424 from SwissProt.40 : >sp|Q9EXN6|MCHE_ECOLI Microcin H47 secretion protein mchE; microcin H47 secretion protein 1180776 mchE 1036922 mchE Escherichia coli CFT073 microcin H47 secretion protein NP_753145.1 1179502 D 199310 CDS NP_753146.1 26247106 1036950 1180751..1182865 1 NC_004431.1 ABC transporter; Residues 7 to 704 of 704 are 98.71 pct identical to residues 1 to 698 of 698 from SwissProt.40 : >sp|Q9EXN5|MCHF_ECOLI Probable microcin H47 secretion ATP-binding protein mchF; microcin H47 secretion ATP-binding protein 1182865 mchF 1036950 mchF Escherichia coli CFT073 microcin H47 secretion ATP-binding protein NP_753146.1 1180751 D 199310 CDS NP_753147.1 26247107 1036879 complement(1183572..1184258) 1 NC_004431.1 Residues 1 to 228 of 228 are 96.92 pct identical to residues 1 to 228 of 228 from GenPept.129 : >emb|CAC43418.1| (X16664) hypothetical protein [Escherichia coli]; hypothetical protein 1184258 1036879 c1233 Escherichia coli CFT073 hypothetical protein NP_753147.1 1183572 R 199310 CDS NP_753148.1 26247108 1036904 complement(1184358..1184828) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1633; hypothetical protein 1184828 1036904 c1234 Escherichia coli CFT073 hypothetical protein NP_753148.1 1184358 R 199310 CDS NP_753149.1 26247109 1036910 1185274..1185786 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1634; hypothetical protein 1185786 1036910 c1235 Escherichia coli CFT073 hypothetical protein NP_753149.1 1185274 D 199310 CDS NP_753150.1 26247110 1035732 1186019..1186597 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1635; hypothetical protein 1186597 1035732 c1236 Escherichia coli CFT073 hypothetical protein NP_753150.1 1186019 D 199310 CDS NP_753151.1 26247111 1036837 complement(1186872..1187156) 1 NC_004431.1 Residues 22 to 94 of 94 are 93.15 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P04743|PAPI_ECOLI Major pilus subunit operon regulatory protein; F1C and S fimbrial switch regulatory protein 1187156 sfaC 1036837 sfaC Escherichia coli CFT073 F1C and S fimbrial switch regulatory protein NP_753151.1 1186872 R 199310 CDS NP_753152.1 26247112 1036582 1187512..1187841 1 NC_004431.1 Residues 1 to 102 of 109 are 82.35 pct identical to residues 1 to 102 of 104 from SwissProt.40 : >sp|P04744|PAPB_ECOLI MAJOR PILU SUBUNIT OPERON REGULATORY PROTEIN PAPB; F1C and S fimbrial switch regulatory protein 1187841 sfaB 1036582 sfaB Escherichia coli CFT073 F1C and S fimbrial switch regulatory protein NP_753152.1 1187512 D 199310 CDS NP_753153.1 26247113 1036891 1188213..1188755 1 NC_004431.1 Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z5912; F1C major fimbrial subunit 1188755 focA 1036891 focA Escherichia coli CFT073 F1C major fimbrial subunit NP_753153.1 1188213 D 199310 CDS NP_753154.1 26247114 1036876 1188841..1189365 1 NC_004431.1 Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913; minor F1C fimbrial subunit 1189365 sfaD 1036876 sfaD Escherichia coli CFT073 minor F1C fimbrial subunit NP_753154.1 1188841 D 199310 CDS NP_753155.1 26247115 1036920 1189406..1190101 1 NC_004431.1 Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z5914; F1C periplasmic chaperone 1190101 focC 1036920 focC Escherichia coli CFT073 F1C periplasmic chaperone NP_753155.1 1189406 D 199310 CDS NP_753156.1 26247116 1036693 1190123..1192801 1 NC_004431.1 Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z5915; F1C fimbrial usher 1192801 focD 1036693 focD Escherichia coli CFT073 F1C fimbrial usher NP_753156.1 1190123 D 199310 CDS NP_753157.1 26247117 1035733 1192814..1193341 1 NC_004431.1 Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916; F1C minor fimbrial subunit F 1193341 focF 1035733 focF Escherichia coli CFT073 F1C minor fimbrial subunit F NP_753157.1 1192814 D 199310 CDS NP_753158.1 26247118 1036842 1193363..1193866 1 NC_004431.1 Escherichia coli K-12 ortholog: b4319; Escherichia coli O157:H7 ortholog: z5917; F1C minor fimbrial subunit protein G presursor 1193866 focG 1036842 focG Escherichia coli CFT073 F1C minor fimbrial subunit protein G presursor NP_753158.1 1193363 D 199310 CDS NP_753159.1 26247119 1036402 1193817..1194827 1 NC_004431.1 Residues 38 to 336 of 336 are 81.60 pct identical to residues 1 to 291 of 291 from SwissProt.40 : >sp|P13431|SFAH_ECOLI S-FIMBRIAL ADHESIN PROTEIN SFAH PRECURSOR; F1C fimbrial adhesin 1194827 focH 1036402 focH Escherichia coli CFT073 F1C fimbrial adhesin NP_753159.1 1193817 D 199310 CDS NP_753160.1 26247120 1034924 1195131..1195871 1 NC_004431.1 Residues 21 to 238 of 246 are 27.35 pct identical to residues 12 to 226 of 232 from GenPept.129 : >emb|CAC93018.1| (AJ414153) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 1195871 1034924 c1246 Escherichia coli CFT073 hypothetical protein NP_753160.1 1195131 D 199310 CDS NP_753161.1 26247121 1034927 1196018..1196569 1 NC_004431.1 Residues 18 to 183 of 183 are 100.00 pct identical to residues 1 to 166 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; regulatory protein 1196569 focX 1034927 focX Escherichia coli CFT073 regulatory protein NP_753161.1 1196018 D 199310 CDS NP_753162.1 26247122 1034929 complement(1196895..1197932) 1 NC_004431.1 Residues 168 to 321 of 345 are 30.57 pct identical to residues 20 to 172 of 188 from GenPept.129 : >dbj|BAB06239.1| (AP001515) transposase related protein (20) [Bacillus halodurans]; hypothetical protein 1197932 1034929 c1248 Escherichia coli CFT073 hypothetical protein NP_753162.1 1196895 R 199310 CDS NP_753163.1 26247123 1034930 1197942..1198136 1 NC_004431.1 hypothetical protein 1198136 1034930 c1249 Escherichia coli CFT073 hypothetical protein NP_753163.1 1197942 D 199310 CDS NP_753164.1 26247124 1034931 1198162..1200339 1 NC_004431.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 1200339 iroN 1034931 iroN Escherichia coli CFT073 outer membrane receptor FepA NP_753164.1 1198162 D 199310 CDS NP_753165.1 26247125 1034932 complement(1200384..1201340) 1 NC_004431.1 Residues 1 to 318 of 318 are 99.37 pct identical to residues 1 to 318 of 318 from GenPept.129 : >emb|CAC43425.1| (X16664) IroE protein [Escherichia coli]; IroE protein 1201340 iroE 1034932 iroE Escherichia coli CFT073 IroE protein NP_753165.1 1200384 R 199310 CDS NP_753166.1 26247126 1034933 complement(1201425..1202654) 1 NC_004431.1 Residues 1 to 409 of 409 are 99.75 pct identical to residues 1 to 409 of 409 from GenPept.129 : >emb|CAC43426.1| (X16664) IroD protein [Escherichia coli]; ferric enterochelin esterase 1202654 iroD 1034933 iroD Escherichia coli CFT073 ferric enterochelin esterase NP_753166.1 1201425 R 199310 CDS NP_753167.1 26247127 1034934 complement(1202758..1206495) 1 NC_004431.1 Residues 27 to 1231 of 1245 are 80.16 pct identical to residues 1 to 1209 of 1218 from GenPept.129 : >emb|CAD05883.1| (AL627276) ABC transporter protein [Salmonella enterica subsp. enterica serovar Typhi]; ABC transporter ATP-binding protein 1206495 iroC 1034934 iroC Escherichia coli CFT073 ABC transporter ATP-binding protein NP_753167.1 1202758 R 199310 CDS NP_753168.1 26247128 1034935 complement(1206557..1207720) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1190; glucosyltransferase 1207720 iroB 1034935 iroB Escherichia coli CFT073 glucosyltransferase NP_753168.1 1206557 R 199310 CDS NP_753169.1 26247129 1034936 1208210..1208509 1 NC_004431.1 hypothetical protein 1208509 1034936 c1255 Escherichia coli CFT073 hypothetical protein NP_753169.1 1208210 D 199310 CDS NP_753170.1 26247130 1034937 1208636..1209145 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1209145 1034937 c1256 Escherichia coli CFT073 hypothetical protein NP_753170.1 1208636 D 199310 CDS NP_753171.1 26247131 1034938 complement(1209273..1209635) 1 NC_004431.1 Residues 8 to 120 of 120 are 98.23 pct identical to residues 316 to 428 of 442 from MG1655 : b4278; hypothetical protein 1209635 1034938 c1257 Escherichia coli CFT073 hypothetical protein NP_753171.1 1209273 R 199310 CDS NP_753172.1 26247132 1034939 1210326..1210688 1 NC_004431.1 hypothetical protein 1210688 1034939 c1258 Escherichia coli CFT073 hypothetical protein NP_753172.1 1210326 D 199310 CDS NP_753173.1 26247133 1034940 1210510..1210944 1 NC_004431.1 Residues 1 to 139 of 144 are 50.71 pct identical to residues 104 to 242 of 258 from GenPept.129 : >gb|AAK18487.1|AF348706_176 (AF348706) orf, hypothetical [Shigella flexneri]; hypothetical protein 1210944 1034940 c1259 Escherichia coli CFT073 hypothetical protein NP_753173.1 1210510 D 199310 CDS NP_753174.1 26247134 1034942 complement(1211507..1211965) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4324; transposase 1211965 1034942 c1260 Escherichia coli CFT073 transposase NP_753174.1 1211507 R 199310 CDS NP_753175.1 26247135 1034943 complement(1211977..1212342) 1 NC_004431.1 Residues 1 to 35 of 121 are 97.14 pct identical to residues 59 to 93 of 316 from GenPept.129 : >gb|AAK18437.1|AF348706_126 (AF348706) transposase [Shigella flexneri]; hypothetical protein 1212342 1034943 c1261 Escherichia coli CFT073 hypothetical protein NP_753175.1 1211977 R 199310 CDS NP_753176.1 26247136 1034944 complement(1212504..1213394) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 1213394 1034944 c1262 Escherichia coli CFT073 transposase IS629 NP_753176.1 1212504 R 199310 CDS NP_753177.1 26247137 1034945 complement(1213391..1213717) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 1213717 1034945 c1263 Escherichia coli CFT073 hypothetical protein NP_753177.1 1213391 R 199310 CDS NP_753178.1 26247138 1034946 complement(1213743..1214183) 1 NC_004431.1 Residues 9 to 146 of 146 are 42.75 pct identical to residues 16 to 160 of 480 from GenPept.129 : >gb|AAG42314.1|AF306519_2 (AF306519) Tn5 transposase [Plasposon pTnMod2-OKm3]; hypothetical protein 1214183 1034946 c1264 Escherichia coli CFT073 hypothetical protein NP_753178.1 1213743 R 199310 CDS NP_753179.1 26247139 1034947 1214529..1216499 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4911; outer membrane heme/hemoglobin receptor 1216499 1034947 c1265 Escherichia coli CFT073 outer membrane heme/hemoglobin receptor NP_753179.1 1214529 D 199310 CDS NP_753180.1 26247140 1034948 1216518..1217309 1 NC_004431.1 Residues 2 to 260 of 263 are 27.61 pct identical to residues 1 to 261 of 268 from GenPept.129 : >emb|CAB84914.1| (AL162756) [Neisseria meningitidis Z2491]; hypothetical protein 1217309 1034948 c1266 Escherichia coli CFT073 hypothetical protein NP_753180.1 1216518 D 199310 CDS NP_753181.1 26247141 1034949 1217510..1218772 1 NC_004431.1 Residues 20 to 413 of 420 are 28.81 pct identical to residues 1 to 390 of 395 from GenPept.129 : >dbj|BAB05509.1| (AP001513) BH1790; unknown conserved protein [Bacillus halodurans]; hypothetical protein 1218772 1034949 c1267 Escherichia coli CFT073 hypothetical protein NP_753181.1 1217510 D 199310 CDS NP_753182.1 26247142 1034950 complement(1218879..1219061) 1 NC_004431.1 Residues 1 to 59 of 60 are 91.52 pct identical to residues 477 to 535 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 1219061 1034950 c1268 Escherichia coli CFT073 hypothetical protein NP_753182.1 1218879 R 199310 CDS NP_753183.1 26247143 1034952 1219723..1220859 1 NC_004431.1 Residues 25 to 254 of 378 are 43.04 pct identical to residues 83 to 310 of 327 from MG1655 : b0644; hypothetical protein 1220859 1034952 c1269 Escherichia coli CFT073 hypothetical protein NP_753183.1 1219723 D 199310 CDS NP_753184.1 26247144 1034953 1220895..1221437 1 NC_004431.1 Residues 1 to 173 of 180 are 37.35 pct identical to residues 1 to 174 of 178 from GenPept.129 : >emb|CAC89258.1| (AJ414142) hypothetical protein [Yersinia pestis]; hypothetical protein 1221437 1034953 c1270 Escherichia coli CFT073 hypothetical protein NP_753184.1 1220895 D 199310 CDS NP_753185.1 26247145 1034954 complement(1223811..1224107) 1 NC_004431.1 Residues 1 to 80 of 98 are 48.75 pct identical to residues 19 to 92 of 520 from GenPept.129 : >emb|CAA31541.1| (X13145) hsdM protein (AA 1-520) [Escherichia coli]; hypothetical protein 1224107 1034954 c1271 Escherichia coli CFT073 hypothetical protein NP_753185.1 1223811 R 199310 CDS NP_753186.1 26247146 1034957 1224407..1225279 1 NC_004431.1 Escherichia coli K-12 ortholog: b1999; Escherichia coli O157:H7 ortholog: z1650; hypothetical protein 1225279 1034957 c1272 Escherichia coli CFT073 hypothetical protein NP_753186.1 1224407 D 199310 CDS NP_753187.1 26247147 1034959 1225454..1228729 1 NC_004431.1 AG43; Sap; Escherichia coli K-12 ortholog: b2000; Escherichia coli O157:H7 ortholog: z1651; antigen 43 1228729 1034959 c1273 Escherichia coli CFT073 antigen 43 NP_753187.1 1225454 D 199310 CDS NP_753188.1 26247148 1034960 1228844..1231366 1 NC_004431.1 Escherichia coli K-12 ortholog: b2001; hypothetical protein 1231366 1034960 c1274 Escherichia coli CFT073 hypothetical protein NP_753188.1 1228844 D 199310 CDS NP_753189.1 26247149 1034962 1231442..1231897 1 NC_004431.1 Residues 9 to 151 of 151 are 98.60 pct identical to residues 1 to 143 of 143 from GenPept.129 : >gb|AAK00476.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 1231897 1034962 c1275 Escherichia coli CFT073 hypothetical protein NP_753189.1 1231442 D 199310 CDS NP_753190.1 26247150 1034964 1231915..1232043 1 NC_004431.1 hypothetical protein 1232043 1034964 c1276 Escherichia coli CFT073 hypothetical protein NP_753190.1 1231915 D 199310 CDS NP_753191.1 26247151 1034965 complement(1232016..1232204) 1 NC_004431.1 hypothetical protein 1232204 1034965 c1277 Escherichia coli CFT073 hypothetical protein NP_753191.1 1232016 R 199310 CDS NP_753192.1 26247152 1034966 1232308..1233129 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 1233129 1034966 c1278 Escherichia coli CFT073 hypothetical protein NP_753192.1 1232308 D 199310 CDS NP_753193.1 26247153 1034967 complement(1232314..1233222) 1 NC_004431.1 Residues 110 to 302 of 302 are 91.19 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAL67348.1|AF447814_16 (AF447814) unknown [Escherichia coli]; hypothetical protein 1233222 1034967 c1279 Escherichia coli CFT073 hypothetical protein NP_753193.1 1232314 R 199310 CDS NP_753194.1 26247154 1034968 1233320..1233865 1 NC_004431.1 Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 1233865 1034968 c1280 Escherichia coli CFT073 hypothetical protein NP_753194.1 1233320 D 199310 CDS NP_753195.1 26247155 1034969 complement(1233386..1234345) 1 NC_004431.1 Residues 1 to 319 of 319 are 92.78 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 1234345 1034969 c1281 Escherichia coli CFT073 hypothetical protein NP_753195.1 1233386 R 199310 CDS NP_753196.1 26247156 1034970 1233881..1234357 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 1234357 1034970 c1282 Escherichia coli CFT073 radC-like protein yeeS NP_753196.1 1233881 D 199310 CDS NP_753197.1 26247157 1034972 1236836..1237057 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 1237057 1034972 c1284 Escherichia coli CFT073 hypothetical protein NP_753197.1 1236836 D 199310 CDS NP_753198.1 26247158 1034974 1237076..1237720 1 NC_004431.1 Residues 178 to 214 of 214 are 78.37 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein 1237720 1034974 c1285 Escherichia coli CFT073 hypothetical protein NP_753198.1 1237076 D 199310 CDS NP_753199.1 26247159 1034975 1237770..1237961 1 NC_004431.1 Residues 1 to 63 of 63 are 98.41 pct identical to residues 37 to 99 of 160 from GenPept.129 : >gb|AAL67343.1|AF447814_11 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 1237961 1034975 c1286 Escherichia coli CFT073 hypothetical protein NP_753199.1 1237770 D 199310 CDS NP_753200.1 26247160 1034978 1237977..1238144 1 NC_004431.1 Residues 1 to 55 of 55 are 98.18 pct identical to residues 106 to 160 of 160 from GenPept.129 : >gb|AAL67343.1|AF447814_11 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 1238144 1034978 c1287 Escherichia coli CFT073 hypothetical protein NP_753200.1 1237977 D 199310 CDS NP_753201.1 26247161 1034979 1238191..1238571 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 1238571 1034979 c1288 Escherichia coli CFT073 hypothetical protein NP_753201.1 1238191 D 199310 CDS NP_753202.1 26247162 1034980 1238568..1239056 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5092; hypothetical protein 1239056 1034980 c1289 Escherichia coli CFT073 hypothetical protein NP_753202.1 1238568 D 199310 CDS NP_753203.1 26247163 1034982 1239076..1239273 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1663; hypothetical protein 1239273 1034982 c1290 Escherichia coli CFT073 hypothetical protein NP_753203.1 1239076 D 199310 CDS NP_753204.1 26247164 1034983 1239426..1239935 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1239935 1034983 c1291 Escherichia coli CFT073 hypothetical protein NP_753204.1 1239426 D 199310 CDS NP_753205.1 26247165 1034984 1240069..1240896 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 1240896 1034984 c1292 Escherichia coli CFT073 hypothetical protein NP_753205.1 1240069 D 199310 CDS NP_753206.1 26247166 1034986 complement(1240486..1240752) 1 NC_004431.1 Residues 42 to 88 of 88 are 87.23 pct identical to residues 8 to 54 of 75 from GenPept.129 : >gb|AAL08482.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 1240752 1034986 c1293 Escherichia coli CFT073 hypothetical protein NP_753206.1 1240486 R 199310 CDS NP_753207.1 26247167 1034989 complement(1241249..1241404) 1 NC_004431.1 hypothetical protein 1241404 1034989 c1294 Escherichia coli CFT073 hypothetical protein NP_753207.1 1241249 R 199310 CDS NP_753208.1 26247168 1034990 1241384..1242322 1 NC_004431.1 Escherichia coli K-12 ortholog: b1033; Escherichia coli O157:H7 ortholog: z1666; 2-hydroxyacid dehydrogenase ycdW 1242322 ycdW 1034990 ycdW Escherichia coli CFT073 2-hydroxyacid dehydrogenase ycdW NP_753208.1 1241384 D 199310 CDS NP_753209.1 26247169 1034991 1242377..1243114 1 NC_004431.1 Escherichia coli K-12 ortholog: b1034; Escherichia coli O157:H7 ortholog: z1667; hydrolase 1243114 ycdX 1034991 ycdX Escherichia coli CFT073 hydrolase NP_753209.1 1242377 D 199310 CDS NP_753210.1 26247170 1034992 1243138..1243692 1 NC_004431.1 Escherichia coli K-12 ortholog: b1035; Escherichia coli O157:H7 ortholog: z1668; hypothetical protein 1243692 ycdY 1034992 ycdY Escherichia coli CFT073 hypothetical protein NP_753210.1 1243138 D 199310 CDS NP_753211.1 26247171 1034993 1243746..1244285 1 NC_004431.1 Escherichia coli K-12 ortholog: b1036; Escherichia coli O157:H7 ortholog: z1669; hypothetical protein 1244285 ycdZ 1034993 ycdZ Escherichia coli CFT073 hypothetical protein NP_753211.1 1243746 D 199310 CDS NP_753212.1 26247172 1034994 complement(1244350..1245183) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1037; Escherichia coli O157:H7 ortholog: z1670; curli production assembly/transport component csgG 1245183 csgG 1034994 csgG Escherichia coli CFT073 curli production assembly/transport component csgG NP_753212.1 1244350 R 199310 CDS NP_753213.1 26247173 1034995 complement(1245210..1245626) 1 NC_004431.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1245626 csgF 1034995 csgF Escherichia coli CFT073 curli assembly protein CsgF NP_753213.1 1245210 R 199310 CDS NP_753214.1 26247174 1034997 complement(1245651..1246040) 1 NC_004431.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1246040 csgE 1034997 csgE Escherichia coli CFT073 curli assembly protein CsgE NP_753214.1 1245651 R 199310 CDS NP_753215.1 26247175 1034998 complement(1246045..1246695) 1 NC_004431.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1246695 csgD 1034998 csgD Escherichia coli CFT073 DNA-binding transcriptional regulator CsgD NP_753215.1 1246045 R 199310 CDS NP_753216.1 26247176 1035001 1246669..1246809 1 NC_004431.1 hypothetical protein 1246809 1035001 c1303 Escherichia coli CFT073 hypothetical protein NP_753216.1 1246669 D 199310 CDS NP_753217.1 26247177 1035002 complement(1247220..1247354) 1 NC_004431.1 Residues 4 to 43 of 44 are 92.50 pct identical to residues 1 to 40 of 79 from GenPept.129 : >dbj|BAB34841.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1247354 1035002 c1304 Escherichia coli CFT073 hypothetical protein NP_753217.1 1247220 R 199310 CDS NP_753218.1 26247178 1035004 1247421..1247903 1 NC_004431.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1247903 csgB 1035004 csgB Escherichia coli CFT073 curlin minor subunit NP_753218.1 1247421 D 199310 CDS NP_753219.1 26247179 1035005 1247944..1248402 1 NC_004431.1 Escherichia coli K-12 ortholog: b1042; Escherichia coli O157:H7 ortholog: z1676; cryptic curlin major subunit 1248402 csgA 1035005 csgA Escherichia coli CFT073 cryptic curlin major subunit NP_753219.1 1247944 D 199310 CDS NP_753220.1 26247180 1035006 1248461..1248793 1 NC_004431.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1248793 csgC 1035006 csgC Escherichia coli CFT073 autoagglutination protein NP_753220.1 1248461 D 199310 CDS NP_753221.1 26247181 1035007 1248914..1249225 1 NC_004431.1 Escherichia coli K-12 ortholog: b1044; Escherichia coli O157:H7 ortholog: z1678; hypothetical protein 1249225 ymdA 1035007 ymdA Escherichia coli CFT073 hypothetical protein NP_753221.1 1248914 D 199310 CDS NP_753222.1 26247182 1035008 1249320..1249853 1 NC_004431.1 Escherichia coli K-12 ortholog: b1045; Escherichia coli O157:H7 ortholog: z1679; hypothetical protein 1249853 ymdB 1035008 ymdB Escherichia coli CFT073 hypothetical protein NP_753222.1 1249320 D 199310 CDS NP_753223.1 26247183 1035009 1249795..1251276 1 NC_004431.1 Escherichia coli K-12 ortholog: b1046; Escherichia coli O157:H7 ortholog: z1680; hypothetical protein 1251276 ymdC 1035009 ymdC Escherichia coli CFT073 hypothetical protein NP_753223.1 1249795 D 199310 CDS NP_753224.1 26247184 1035010 complement(1251284..1252441) 1 NC_004431.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1252441 mdoC 1035010 mdoC Escherichia coli CFT073 glucans biosynthesis protein NP_753224.1 1251284 R 199310 CDS NP_753225.1 26247185 1035011 complement(1252486..1252629) 1 NC_004431.1 hypothetical protein 1252629 1035011 c1312 Escherichia coli CFT073 hypothetical protein NP_753225.1 1252486 R 199310 CDS NP_753226.1 26247186 1035012 1252817..1254370 1 NC_004431.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1254370 mdoG 1035012 mdoG Escherichia coli CFT073 glucan biosynthesis protein G NP_753226.1 1252817 D 199310 CDS NP_753227.1 26247187 1035014 1254333..1256906 1 NC_004431.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1256906 mdoH 1035014 mdoH Escherichia coli CFT073 glucosyltransferase MdoH NP_753227.1 1254333 D 199310 CDS NP_753228.1 26247188 1035015 1256915..1257139 1 NC_004431.1 Residues 1 to 35 of 74 are 68.57 pct identical to residues 20 to 54 of 54 from GenPept.129 : >gb|AAC76157.1| (AE000394) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 1257139 1035015 c1315 Escherichia coli CFT073 hypothetical protein NP_753228.1 1256915 D 199310 CDS NP_753229.1 26247189 1035016 1257078..1257305 1 NC_004431.1 Escherichia coli K-12 ortholog: b1050; Escherichia coli O157:H7 ortholog: z1685; hypothetical protein 1257305 yceK 1035016 yceK Escherichia coli CFT073 hypothetical protein NP_753229.1 1257078 D 199310 CDS NP_753230.1 26247190 1035017 complement(1257287..1257661) 1 NC_004431.1 hypothetical protein 1257661 1035017 c1317 Escherichia coli CFT073 hypothetical protein NP_753230.1 1257287 R 199310 CDS NP_753231.1 26247191 1035018 complement(1257306..1257683) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1051; Escherichia coli O157:H7 ortholog: z1686; hypothetical protein 1257683 msyB 1035018 msyB Escherichia coli CFT073 hypothetical protein NP_753231.1 1257306 R 199310 CDS NP_753232.1 26247192 1035019 complement(1257763..1258989) 1 NC_004431.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1258989 yceE 1035019 yceE Escherichia coli CFT073 drug efflux system protein MdtG NP_753232.1 1257763 R 199310 CDS NP_753233.2 161486253 1035020 complement(1259161..1260081) 1 NC_004431.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1260081 htrB 1035020 htrB Escherichia coli CFT073 lipid A biosynthesis lauroyl acyltransferase NP_753233.2 1259161 R 199310 CDS NP_753234.1 26247194 1035021 1260252..1261358 1 NC_004431.1 ORF39.; Escherichia coli K-12 ortholog: b1055; Escherichia coli O157:H7 ortholog: z1691; hypothetical protein 1261358 yceA 1035021 yceA Escherichia coli CFT073 hypothetical protein NP_753234.1 1260252 D 199310 CDS NP_753235.1 26247195 1035022 complement(1261400..1261975) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1056; Escherichia coli O157:H7 ortholog: z1692; hypothetical protein 1261975 yceI 1035022 yceI Escherichia coli CFT073 hypothetical protein NP_753235.1 1261400 R 199310 CDS NP_753236.1 26247196 1035023 complement(1261979..1262557) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1057; Escherichia coli O157:H7 ortholog: z1693; cytochrome b561 2 1262557 1035023 c1323 Escherichia coli CFT073 cytochrome b561 2 NP_753236.1 1261979 R 199310 CDS NP_753237.1 26247197 1035024 1262535..1262681 1 NC_004431.1 hypothetical protein 1262681 1035024 c1324 Escherichia coli CFT073 hypothetical protein NP_753237.1 1262535 D 199310 CDS NP_753238.1 26247198 1035025 complement(1262807..1262944) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1058; Escherichia coli O157:H7 ortholog: z1695; hypothetical protein 1262944 yceO 1035025 yceO Escherichia coli CFT073 hypothetical protein NP_753238.1 1262807 R 199310 CDS NP_753239.1 26247199 1035026 complement(1262965..1264083) 1 NC_004431.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1264083 solA 1035026 solA Escherichia coli CFT073 N-methyltryptophan oxidase NP_753239.1 1262965 R 199310 CDS NP_753240.2 161486252 1035027 complement(1264198..1264452) 1 NC_004431.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1264452 bssS 1035027 bssS Escherichia coli CFT073 biofilm formation regulatory protein BssS NP_753240.2 1264198 R 199310 CDS NP_753241.2 229106383 1035028 complement(1264742..1264987) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1061; Escherichia coli O157:H7 ortholog: z1698; DNA damage-inducible protein I 1264987 dinI 1035028 dinI Escherichia coli CFT073 DNA damage-inducible protein I NP_753241.2 1264742 R 199310 CDS NP_753242.1 26247202 1035029 complement(1265061..1266107) 1 NC_004431.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1266107 pyrC 1035029 pyrC Escherichia coli CFT073 dihydroorotase NP_753242.1 1265061 R 199310 CDS NP_753243.1 26247203 1035030 complement(1266213..1266830) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1063; Escherichia coli O157:H7 ortholog: z1700; hypothetical protein 1266830 yceB 1035030 yceB Escherichia coli CFT073 hypothetical protein NP_753243.1 1266213 R 199310 CDS NP_753244.1 26247204 1035031 complement(1266907..1267554) 1 NC_004431.1 cofactor involved in the reduction of disulfides; glutaredoxin 2 1267554 grxB 1035031 grxB Escherichia coli CFT073 glutaredoxin 2 NP_753244.1 1266907 R 199310 CDS NP_753245.2 161486251 1035032 complement(1267618..1268826) 1 NC_004431.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1268826 yceL 1035032 yceL Escherichia coli CFT073 multidrug resistance protein MdtH NP_753245.2 1267618 R 199310 CDS NP_753246.1 26247206 1035033 1269062..1269646 1 NC_004431.1 Escherichia coli K-12 ortholog: b1066; Escherichia coli O157:H7 ortholog: z1703; Acetylating enzyme for N-terminal of ribosomal protein S5; ribosomal-protein-S5-alanine N-acetyltransferase 1269646 rimJ 1035033 rimJ Escherichia coli CFT073 ribosomal-protein-S5-alanine N-acetyltransferase NP_753246.1 1269062 D 199310 CDS NP_753247.1 26247207 1035034 1269657..1270304 1 NC_004431.1 G20.3; Escherichia coli K-12 ortholog: b1067; Escherichia coli O157:H7 ortholog: z1704; hypothetical protein 1270304 yceH 1035034 yceH Escherichia coli CFT073 hypothetical protein NP_753247.1 1269657 D 199310 CDS NP_753248.1 26247208 1035037 complement(1270867..1271265) 1 NC_004431.1 hypothetical protein 1271265 1035037 c1337 Escherichia coli CFT073 hypothetical protein NP_753248.1 1270867 R 199310 CDS NP_753249.1 26247209 1035038 1271342..1272877 1 NC_004431.1 Escherichia coli K-12 ortholog: b1069; Escherichia coli O157:H7 ortholog: z1707; virulence factor mviN-like protein 1272877 mviN 1035038 mviN Escherichia coli CFT073 virulence factor mviN-like protein NP_753249.1 1271342 D 199310 CDS NP_753250.1 26247210 1035039 complement(1272917..1273333) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1070; Escherichia coli O157:H7 ortholog: z1708; flagellar synthesis protein FlgN 1273333 flgN 1035039 flgN Escherichia coli CFT073 flagellar synthesis protein FlgN NP_753250.1 1272917 R 199310 CDS NP_753251.1 26247211 1035040 complement(1273338..1273631) 1 NC_004431.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 1273631 flgM 1035040 flgM Escherichia coli CFT073 anti-sigma28 factor FlgM NP_753251.1 1273338 R 199310 CDS NP_753252.1 26247212 1035041 complement(1273707..1274366) 1 NC_004431.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1274366 flgA 1035041 flgA Escherichia coli CFT073 flagellar basal body P-ring biosynthesis protein FlgA NP_753252.1 1273707 R 199310 CDS NP_753253.1 26247213 1035042 1274522..1274938 1 NC_004431.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1274938 flgB 1035042 flgB Escherichia coli CFT073 flagellar basal-body rod protein FlgB NP_753253.1 1274522 D 199310 CDS NP_753254.1 26247214 1035043 1274942..1275346 1 NC_004431.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1275346 flgC 1035043 flgC Escherichia coli CFT073 flagellar basal body rod protein FlgC NP_753254.1 1274942 D 199310 CDS NP_753255.1 26247215 1035044 1275358..1276053 1 NC_004431.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1276053 flgD 1035044 flgD Escherichia coli CFT073 flagellar basal body rod modification protein NP_753255.1 1275358 D 199310 CDS NP_753256.1 26247216 1035045 1276078..1277283 1 NC_004431.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1277283 flgE 1035045 flgE Escherichia coli CFT073 flagellar hook protein FlgE NP_753256.1 1276078 D 199310 CDS NP_753257.1 26247217 1035046 1277303..1278058 1 NC_004431.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1278058 flgF 1035046 flgF Escherichia coli CFT073 flagellar basal body rod protein FlgF NP_753257.1 1277303 D 199310 CDS NP_753258.1 26247218 1035047 1278230..1279012 1 NC_004431.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1279012 flgG 1035047 flgG Escherichia coli CFT073 flagellar basal body rod protein FlgG NP_753258.1 1278230 D 199310 CDS NP_753259.1 26247219 1035048 1279050..1279763 1 NC_004431.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1279763 flgH 1035048 flgH Escherichia coli CFT073 flagellar basal body L-ring protein NP_753259.1 1279050 D 199310 CDS NP_753260.1 26247220 1035049 1279772..1280872 1 NC_004431.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1280872 flgI 1035049 flgI Escherichia coli CFT073 flagellar basal body P-ring biosynthesis protein FlgA NP_753260.1 1279772 D 199310 CDS NP_753261.2 161486250 1035050 1280872..1281813 1 NC_004431.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1281813 flgJ 1035050 flgJ Escherichia coli CFT073 flagellar rod assembly protein/muramidase FlgJ NP_753261.2 1280872 D 199310 CDS NP_753262.1 26247222 1035051 1281879..1283522 1 NC_004431.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1283522 flgK 1035051 flgK Escherichia coli CFT073 flagellar hook-associated protein FlgK NP_753262.1 1281879 D 199310 CDS NP_753263.1 26247223 1035052 1283534..1284487 1 NC_004431.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1284487 flgL 1035052 flgL Escherichia coli CFT073 flagellar hook-associated protein FlgL NP_753263.1 1283534 D 199310 CDS NP_753264.1 26247224 1035053 complement(1284682..1287867) 1 NC_004431.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1287867 rne 1035053 rne Escherichia coli CFT073 ribonuclease E NP_753264.1 1284682 R 199310 CDS NP_753265.1 26247225 1035054 1287948..1288322 1 NC_004431.1 Escherichia coli K-12 ortholog: b1085; Escherichia coli O157:H7 ortholog: z1724; hypothetical protein 1288322 1035054 c1354 Escherichia coli CFT073 hypothetical protein NP_753265.1 1287948 D 199310 CDS NP_753266.1 26247226 1035055 1288440..1289399 1 NC_004431.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1289399 rluC 1035055 rluC Escherichia coli CFT073 23S rRNA pseudouridylate synthase C NP_753266.1 1288440 D 199310 CDS NP_753267.2 161486249 1035056 complement(1289511..1290095) 1 NC_004431.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1290095 maf 1035056 maf Escherichia coli CFT073 Maf-like protein NP_753267.2 1289511 R 199310 CDS NP_753268.1 26247228 1035057 complement(1290107..1290235) 1 NC_004431.1 hypothetical protein 1290235 1035057 c1357 Escherichia coli CFT073 hypothetical protein NP_753268.1 1290107 R 199310 CDS NP_753269.1 26247229 1035058 1290293..1290814 1 NC_004431.1 G30K; Escherichia coli K-12 ortholog: b1088; Escherichia coli O157:H7 ortholog: z1727; hypothetical protein 1290814 yceD 1035058 yceD Escherichia coli CFT073 hypothetical protein NP_753269.1 1290293 D 199310 CDS NP_753270.1 26247230 1035059 1291120..1292190 1 NC_004431.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1292190 plsX 1035059 plsX Escherichia coli CFT073 glycerol-3-phosphate acyltransferase PlsX NP_753270.1 1291120 D 199310 CDS NP_753271.1 26247231 1035060 1292258..1293211 1 NC_004431.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1293211 fabH 1035060 fabH Escherichia coli CFT073 3-oxoacyl-ACP synthase NP_753271.1 1292258 D 199310 CDS NP_753272.1 26247232 1035061 1293227..1294156 1 NC_004431.1 Escherichia coli K-12 ortholog: b1092; Escherichia coli O157:H7 ortholog: z1731; ACP S-malonyltransferase 1294156 fabD 1035061 fabD Escherichia coli CFT073 ACP S-malonyltransferase NP_753272.1 1293227 D 199310 CDS NP_753273.1 26247233 1035062 complement(1295063..1295437) 1 NC_004431.1 hypothetical protein 1295437 1035062 c1363 Escherichia coli CFT073 hypothetical protein NP_753273.1 1295063 R 199310 CDS NP_753274.1 26247234 1035063 1295117..1295353 1 NC_004431.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1295353 acpP 1035063 acpP Escherichia coli CFT073 acyl carrier protein NP_753274.1 1295117 D 199310 CDS NP_753275.1 26247235 1035064 1295440..1296681 1 NC_004431.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1296681 fabF 1035064 fabF Escherichia coli CFT073 3-oxoacyl-ACP synthase NP_753275.1 1295440 D 199310 CDS NP_753276.1 26247236 1035065 1296801..1297583 1 NC_004431.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1297583 pabC 1035065 pabC Escherichia coli CFT073 4-amino-4-deoxychorismate lyase NP_753276.1 1296801 D 199310 CDS YP_004853805.1 347357927 1035066 1297593..1297772 1 NC_004431.1 hypothetical protein 1297772 1035066 c1367 Escherichia coli CFT073 hypothetical protein YP_004853805.1 1297593 D 199310 CDS YP_004853806.1 347357928 1035067 1297612..1297746 1 NC_004431.1 hypothetical protein 1297746 1035067 c1368 Escherichia coli CFT073 hypothetical protein YP_004853806.1 1297612 D 199310 CDS NP_753279.1 26247239 1035068 1297826..1298635 1 NC_004431.1 Escherichia coli K-12 ortholog: b1097; Escherichia coli O157:H7 ortholog: z1736; hypothetical protein 1298635 yceG 1035068 yceG Escherichia coli CFT073 hypothetical protein NP_753279.1 1297826 D 199310 CDS NP_753280.1 26247240 1035069 1298625..1299266 1 NC_004431.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1299266 tmk 1035069 tmk Escherichia coli CFT073 thymidylate kinase NP_753280.1 1298625 D 199310 CDS NP_753281.1 26247241 1035070 1299263..1300267 1 NC_004431.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1300267 holB 1035070 holB Escherichia coli CFT073 DNA polymerase III subunit delta' NP_753281.1 1299263 D 199310 CDS NP_753282.2 229106382 1035071 1300278..1301075 1 NC_004431.1 Escherichia coli K-12 ortholog: b1100; Escherichia coli O157:H7 ortholog: z1739; metallodependent hydrolase 1301075 ycfH 1035071 ycfH Escherichia coli CFT073 metallodependent hydrolase NP_753282.2 1300278 D 199310 CDS NP_753283.1 26247243 1035072 1301370..1302803 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1302803 ptsG 1035072 ptsG Escherichia coli CFT073 PTS system glucose-specific transporter subunits IIBC NP_753283.1 1301370 D 199310 CDS NP_753284.1 26247244 1035073 complement(1302863..1305052) 1 NC_004431.1 Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid; Escherichia coli K-12 ortholog: b1102; Escherichia coli O157:H7 ortholog: z1741; ferric-rhodotorulic acid outer membrane transporter 1305052 fhuE 1035073 fhuE Escherichia coli CFT073 ferric-rhodotorulic acid outer membrane transporter NP_753284.1 1302863 R 199310 CDS NP_753285.1 26247245 1035074 complement(1305085..1305255) 1 NC_004431.1 hypothetical protein 1305255 1035074 c1375 Escherichia coli CFT073 hypothetical protein NP_753285.1 1305085 R 199310 CDS NP_753286.1 26247246 1035075 1305368..1305745 1 NC_004431.1 Escherichia coli K-12 ortholog: b1103; Escherichia coli O157:H7 ortholog: z1742; purine nucleoside phosphoramidase 1305745 ycfF 1035075 ycfF Escherichia coli CFT073 purine nucleoside phosphoramidase NP_753286.1 1305368 D 199310 CDS NP_753287.1 26247247 1035076 1305748..1306125 1 NC_004431.1 Escherichia coli K-12 ortholog: b1104; Escherichia coli O157:H7 ortholog: z1743; hypothetical protein 1306125 ycfL 1035076 ycfL Escherichia coli CFT073 hypothetical protein NP_753287.1 1305748 D 199310 CDS NP_753288.1 26247248 1035077 1306136..1306780 1 NC_004431.1 Escherichia coli K-12 ortholog: b1105; Escherichia coli O157:H7 ortholog: z1744; hypothetical protein 1306780 ycfM 1035077 ycfM Escherichia coli CFT073 hypothetical protein NP_753288.1 1306136 D 199310 CDS NP_753289.1 26247249 1035078 1306761..1307585 1 NC_004431.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1307585 thiK 1035078 thiK Escherichia coli CFT073 thiamine kinase NP_753289.1 1306761 D 199310 CDS NP_753290.1 26247250 1035079 1307596..1308621 1 NC_004431.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1308621 nagZ 1035079 nagZ Escherichia coli CFT073 beta-hexosaminidase NP_753290.1 1307596 D 199310 CDS NP_753291.2 161486248 1035080 1308644..1309186 1 NC_004431.1 Escherichia coli K-12 ortholog: b1108; Escherichia coli O157:H7 ortholog: z1747; hypothetical protein 1309186 ycfP 1035080 ycfP Escherichia coli CFT073 hypothetical protein NP_753291.2 1308644 D 199310 CDS NP_753292.1 26247252 1035081 1309558..1310889 1 NC_004431.1 Escherichia coli K-12 ortholog: b1109; Escherichia coli O157:H7 ortholog: z1748; NADH dehydrogenase 1310889 ndh 1035081 ndh Escherichia coli CFT073 NADH dehydrogenase NP_753292.1 1309558 D 199310 CDS NP_753293.1 26247253 1035083 1311077..1311655 1 NC_004431.1 Escherichia coli K-12 ortholog: b1110; Escherichia coli O157:H7 ortholog: z1749; hypothetical protein 1311655 ycfJ 1035083 ycfJ Escherichia coli CFT073 hypothetical protein NP_753293.1 1311077 D 199310 CDS NP_753294.1 26247254 1035084 1311803..1312312 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1312312 1035084 c1384 Escherichia coli CFT073 hypothetical protein NP_753294.1 1311803 D 199310 CDS NP_753295.1 26247255 1035085 complement(1312428..1313138) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1111; Escherichia coli O157:H7 ortholog: z1750; transcriptional regulator YcfQ 1313138 ycfQ 1035085 ycfQ Escherichia coli CFT073 transcriptional regulator YcfQ NP_753295.1 1312428 R 199310 CDS NP_753296.1 26247256 1035087 1313301..1313558 1 NC_004431.1 Escherichia coli K-12 ortholog: b1112; Escherichia coli O157:H7 ortholog: z1751; hypothetical protein 1313558 ycfR 1035087 ycfR Escherichia coli CFT073 hypothetical protein NP_753296.1 1313301 D 199310 CDS NP_753297.1 26247257 1035088 complement(1313640..1314773) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1113; Escherichia coli O157:H7 ortholog: z1752; hypothetical protein 1314773 ycfS 1035088 ycfS Escherichia coli CFT073 hypothetical protein NP_753297.1 1313640 R 199310 CDS NP_753298.1 26247258 1035091 complement(1315400..1318255) 1 NC_004431.1 TRCF; Escherichia coli K-12 ortholog: b1114; Escherichia coli O157:H7 ortholog: z1754; transcription-repair coupling factor 1318255 mfd 1035091 mfd Escherichia coli CFT073 transcription-repair coupling factor NP_753298.1 1315400 R 199310 CDS NP_753299.1 26247259 1035092 complement(1318320..1319393) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1115; Escherichia coli O157:H7 ortholog: z1756; hypothetical protein 1319393 ycfT 1035092 ycfT Escherichia coli CFT073 hypothetical protein NP_753299.1 1318320 R 199310 CDS NP_753300.1 26247260 1035095 1319654..1320853 1 NC_004431.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1320853 lolC 1035095 lolC Escherichia coli CFT073 outer membrane-specific lipoprotein transporter subunit LolC NP_753300.1 1319654 D 199310 CDS NP_753301.1 26247261 1035096 1320846..1321547 1 NC_004431.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1321547 lolD 1035096 lolD Escherichia coli CFT073 lipoprotein transporter ATP-binding subunit NP_753301.1 1320846 D 199310 CDS NP_753302.1 26247262 1035097 1321547..1322791 1 NC_004431.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1322791 lolE 1035097 lolE Escherichia coli CFT073 outer membrane-specific lipoprotein transporter subunit LolE NP_753302.1 1321547 D 199310 CDS NP_753303.1 26247263 1035098 1322820..1323731 1 NC_004431.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1323731 ycfX 1035098 ycfX Escherichia coli CFT073 N-acetyl-D-glucosamine kinase NP_753303.1 1322820 D 199310 CDS NP_753304.1 26247264 1035099 1323747..1324568 1 NC_004431.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1324568 cobB 1035099 cobB Escherichia coli CFT073 NAD-dependent deacetylase NP_753304.1 1323747 D 199310 CDS NP_753305.1 26247265 1035100 complement(1324706..1325494) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1121; hypothetical protein 1325494 ycfZ 1035100 ycfZ Escherichia coli CFT073 hypothetical protein NP_753305.1 1324706 R 199310 CDS NP_753306.1 26247266 1035101 complement(1325491..1325994) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1122; hypothetical protein 1325994 ymfA 1035101 ymfA Escherichia coli CFT073 hypothetical protein NP_753306.1 1325491 R 199310 CDS NP_753307.1 26247267 1035102 complement(1326010..1327056) 1 NC_004431.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein 1327056 potD 1035102 potD Escherichia coli CFT073 spermidine/putrescine ABC transporter periplasmic substrate-binding protein NP_753307.1 1326010 R 199310 CDS NP_753308.1 26247268 1035103 complement(1327053..1327847) 1 NC_004431.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1327847 potC 1035103 potC Escherichia coli CFT073 spermidine/putrescine ABC transporter membrane protein NP_753308.1 1327053 R 199310 CDS NP_753309.1 26247269 1035104 complement(1328014..1329132) 1 NC_004431.1 Int(Lambda); Escherichia coli K-12 ortholog: b1140; Escherichia coli O157:H7 ortholog: z1764; prophage lambda integrase 1329132 1035104 c1400 Escherichia coli CFT073 prophage lambda integrase NP_753309.1 1328014 R 199310 CDS NP_753310.1 26247270 1035105 complement(1329101..1329379) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1765; excisionase for prophage 1329379 xisN 1035105 xisN Escherichia coli CFT073 excisionase for prophage NP_753310.1 1329101 R 199310 CDS NP_753311.1 26247271 1035108 complement(1329432..1331873) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1350; exodeoxyribonuclease VIII 1331873 recE 1035108 recE Escherichia coli CFT073 exodeoxyribonuclease VIII NP_753311.1 1329432 R 199310 CDS NP_753312.1 26247272 1035109 1331937..1332482 1 NC_004431.1 hypothetical protein 1332482 1035109 c1403 Escherichia coli CFT073 hypothetical protein NP_753312.1 1331937 D 199310 CDS NP_753313.1 26247273 1035110 complement(1331967..1332167) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1576; Escherichia coli O157:H7 ortholog: z6079; hypothetical protein 1332167 ydfD 1035110 ydfD Escherichia coli CFT073 hypothetical protein NP_753313.1 1331967 R 199310 CDS NP_753314.1 26247274 1035112 complement(1332155..1332448) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1575; Escherichia coli O157:H7 ortholog: z6078; division inhibition protein dicB 1332448 dicB 1035112 dicB Escherichia coli CFT073 division inhibition protein dicB NP_753314.1 1332155 R 199310 CDS NP_753315.1 26247275 1035113 1332454..1332609 1 NC_004431.1 hypothetical protein 1332609 1035113 c1406 Escherichia coli CFT073 hypothetical protein NP_753315.1 1332454 D 199310 CDS NP_753316.1 26247276 1035114 complement(1332912..1333130) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1573; Escherichia coli O157:H7 ortholog: z6076; hypothetical protein 1333130 ydfC 1035114 ydfC Escherichia coli CFT073 hypothetical protein NP_753316.1 1332912 R 199310 CDS NP_753317.1 26247277 1035115 complement(1333160..1333330) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1572; Escherichia coli O157:H7 ortholog: z1330; hypothetical protein 1333330 ydfB 1035115 ydfB Escherichia coli CFT073 hypothetical protein NP_753317.1 1333160 R 199310 CDS NP_753318.1 26247278 1035116 complement(1333290..1333526) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1571; Escherichia coli O157:H7 ortholog: z2089; hypothetical protein 1333526 ydfA 1035116 ydfA Escherichia coli CFT073 hypothetical protein NP_753318.1 1333290 R 199310 CDS NP_753319.1 26247279 1035117 complement(1333711..1334130) 1 NC_004431.1 Residues 90 to 139 of 139 are 72.00 pct identical to residues 54 to 103 of 103 from GenPept.129 : >dbj|BAB35364.1| (AP002556) transcriptional regulator [Escherichia coli O157:H7]; hypothetical protein 1334130 1035117 c1410 Escherichia coli CFT073 hypothetical protein NP_753319.1 1333711 R 199310 CDS NP_753320.1 26247280 1035118 1334496..1334921 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1335; hypothetical protein 1334921 1035118 c1411 Escherichia coli CFT073 hypothetical protein NP_753320.1 1334496 D 199310 CDS NP_753321.1 26247281 1035119 1335062..1336057 1 NC_004431.1 Residues 97 to 331 of 331 are 79.14 pct identical to residues 177 to 400 of 400 from GenPept.129 : >gb|AAG55470.1|AE005288_1 (AE005288) unknown protein encoded by cryptic prophage CP-933M [Escherichia coli O157:H7 EDL933]; hypothetical protein 1336057 1035119 c1412 Escherichia coli CFT073 hypothetical protein NP_753321.1 1335062 D 199310 CDS NP_753322.1 26247282 1035120 1336098..1336520 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2394; hypothetical protein 1336520 1035120 c1413 Escherichia coli CFT073 hypothetical protein NP_753322.1 1336098 D 199310 CDS NP_753323.1 26247283 1035121 1336521..1336934 1 NC_004431.1 Residues 3 to 137 of 137 are 94.07 pct identical to residues 1 to 135 of 135 from GenPept.129 : >emb|CAD05603.1| (AL627272) bacteriophage protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 1336934 1035121 c1414 Escherichia coli CFT073 hypothetical protein NP_753323.1 1336521 D 199310 CDS NP_753324.1 26247284 1035122 complement(1336989..1337126) 1 NC_004431.1 hypothetical protein 1337126 1035122 c1415 Escherichia coli CFT073 hypothetical protein NP_753324.1 1336989 R 199310 CDS NP_753325.1 26247285 1035123 1337028..1337210 1 NC_004431.1 hypothetical protein 1337210 1035123 c1416 Escherichia coli CFT073 hypothetical protein NP_753325.1 1337028 D 199310 CDS NP_753326.1 26247286 1035124 1337203..1337379 1 NC_004431.1 Residues 1 to 58 of 58 are 86.20 pct identical to residues 21 to 78 of 78 from GenPept.129 : >dbj|BAB12674.1| (AP002527) yheA [Escherichia coli]; hypothetical protein 1337379 1035124 c1417 Escherichia coli CFT073 hypothetical protein NP_753326.1 1337203 D 199310 CDS NP_753327.1 26247287 1035127 1337824..1338042 1 NC_004431.1 hypothetical protein 1338042 1035127 c1418 Escherichia coli CFT073 hypothetical protein NP_753327.1 1337824 D 199310 CDS NP_753328.1 26247288 1035129 1338495..1338626 1 NC_004431.1 hypothetical protein 1338626 1035129 c1419 Escherichia coli CFT073 hypothetical protein NP_753328.1 1338495 D 199310 CDS NP_753329.1 26247289 1035130 complement(1338498..1338659) 1 NC_004431.1 hypothetical protein 1338659 1035130 c1420 Escherichia coli CFT073 hypothetical protein NP_753329.1 1338498 R 199310 CDS NP_753330.1 26247290 1035131 1338915..1339193 1 NC_004431.1 Residues 1 to 92 of 92 are 93.47 pct identical to residues 1 to 92 of 92 from GenPept.129 : >dbj|BAB34944.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1339193 1035131 c1421 Escherichia coli CFT073 hypothetical protein NP_753330.1 1338915 D 199310 CDS NP_753331.1 26247291 1035132 complement(1338933..1339112) 1 NC_004431.1 Residues 1 to 59 of 59 are 69.49 pct identical to residues 1 to 59 of 107 from GenPept.129 : >gb|AAG57026.1|AE005422_1 (AE005422) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein 1339112 1035132 c1422 Escherichia coli CFT073 hypothetical protein NP_753331.1 1338933 R 199310 CDS NP_753332.1 26247292 1035133 1339195..1340244 1 NC_004431.1 Escherichia coli K-12 ortholog: b1560; Escherichia coli O157:H7 ortholog: z3116; hypothetical protein 1340244 1035133 c1423 Escherichia coli CFT073 hypothetical protein NP_753332.1 1339195 D 199310 CDS YP_004853807.1 347357929 1035134 1340250..1340450 1 NC_004431.1 hypothetical protein 1340450 1035134 c1424 Escherichia coli CFT073 hypothetical protein YP_004853807.1 1340250 D 199310 CDS NP_753334.1 26247294 1035135 1340428..1340613 1 NC_004431.1 Residues 1 to 60 of 61 are 94.99 pct identical to residues 58 to 117 of 124 from GenPept.129 : >gb|AAG55477.1|AE005288_8 (AE005288) endonuclease of cryptic prophage CP-933M [Escherichia coli O157:H7 EDL933]; hypothetical protein 1340613 1035135 c1425 Escherichia coli CFT073 hypothetical protein NP_753334.1 1340428 D 199310 CDS NP_753335.1 26247295 1035136 1340628..1341449 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1345; cryptic prophage antitermination protein Q 1341449 1035136 c1426 Escherichia coli CFT073 cryptic prophage antitermination protein Q NP_753335.1 1340628 D 199310 CDS NP_753336.1 26247296 1035137 1341649..1342158 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1342158 1035137 c1427 Escherichia coli CFT073 hypothetical protein NP_753336.1 1341649 D 199310 CDS NP_753337.1 26247297 1035142 1343053..1343184 1 NC_004431.1 hypothetical protein 1343184 1035142 c1428 Escherichia coli CFT073 hypothetical protein NP_753337.1 1343053 D 199310 CDS NP_753338.1 26247298 1035144 complement(1343465..1343800) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1160; hypothetical protein 1343800 ycgW 1035144 ycgW Escherichia coli CFT073 hypothetical protein NP_753338.1 1343465 R 199310 CDS NP_753339.1 26247299 1035145 complement(1343926..1344075) 1 NC_004431.1 hypothetical protein 1344075 1035145 c1430 Escherichia coli CFT073 hypothetical protein NP_753339.1 1343926 R 199310 CDS NP_753340.1 26247300 1035146 1344049..1344249 1 NC_004431.1 Residues 5 to 66 of 66 are 93.54 pct identical to residues 1 to 62 of 616 from GenPept.129 : >emb|CAC05558.1| (AJ251754) ORF616 [Escherichia coli]; hypothetical protein 1344249 1035146 c1431 Escherichia coli CFT073 hypothetical protein NP_753340.1 1344049 D 199310 CDS NP_753341.1 26247301 1035147 1344246..1344407 1 NC_004431.1 Residues 8 to 53 of 53 are 86.95 pct identical to residues 572 to 617 of 617 from GenPept.129 : >gb|AAG57020.1|AE005421_8 (AE005421) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein 1344407 1035147 c1432 Escherichia coli CFT073 hypothetical protein NP_753341.1 1344246 D 199310 CDS NP_753342.1 26247302 1035148 1344452..1344772 1 NC_004431.1 Escherichia coli K-12 ortholog: b0554; Escherichia coli O157:H7 ortholog: z3106; lambdoid prophage DLP12 lysis protein S 1344772 1035148 c1433 Escherichia coli CFT073 lambdoid prophage DLP12 lysis protein S NP_753342.1 1344452 D 199310 CDS NP_753343.1 26247303 1035149 1344777..1345121 1 NC_004431.1 Escherichia coli K-12 ortholog: b1555; Escherichia coli O157:H7 ortholog: z2070; hypothetical protein 1345121 ydfR 1035149 ydfR Escherichia coli CFT073 hypothetical protein NP_753343.1 1344777 D 199310 CDS NP_753344.1 26247304 1035150 complement(1345087..1345365) 1 NC_004431.1 hypothetical protein 1345365 1035150 c1435 Escherichia coli CFT073 hypothetical protein NP_753344.1 1345087 R 199310 CDS NP_753345.1 26247305 1035151 1345465..1345998 1 NC_004431.1 Escherichia coli K-12 ortholog: b1554; Escherichia coli O157:H7 ortholog: z1796; lysozyme from lambdoid prophage Qin 1345998 1035151 c1436 Escherichia coli CFT073 lysozyme from lambdoid prophage Qin NP_753345.1 1345465 D 199310 CDS NP_753346.1 26247306 1035153 1345980..1346462 1 NC_004431.1 Escherichia coli K-12 ortholog: b0556; Escherichia coli O157:H7 ortholog: z0961; Rz endopeptidase from lambdoid prophage DLP12 1346462 1035153 c1437 Escherichia coli CFT073 Rz endopeptidase from lambdoid prophage DLP12 NP_753346.1 1345980 D 199310 CDS NP_753347.1 26247307 1035154 1346450..1346602 1 NC_004431.1 Residues 1 to 50 of 50 are 92.00 pct identical to residues 1 to 50 of 50 from GenPept.129 : >dbj|BAB34245.1| (AP002553) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1346602 1035154 c1438 Escherichia coli CFT073 hypothetical protein NP_753347.1 1346450 D 199310 CDS NP_753348.1 26247308 1035155 1346769..1347329 1 NC_004431.1 Residues 1 to 185 of 186 are 74.59 pct identical to residues 1 to 183 of 184 from GenPept.129 : >gb|AAA82105.1| (L40418) alternate start at bp 59; ORF [Bacteriophage phi-80]; hypothetical protein 1347329 1035155 c1439 Escherichia coli CFT073 hypothetical protein NP_753348.1 1346769 D 199310 CDS NP_753349.1 26247309 1035156 complement(1347632..1348057) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1549; Escherichia coli O157:H7 ortholog: z1879; hypothetical protein 1348057 ydfO 1035156 ydfO Escherichia coli CFT073 hypothetical protein NP_753349.1 1347632 R 199310 CDS NP_753350.1 26247310 1035157 1348095..1348244 1 NC_004431.1 hypothetical protein 1348244 1035157 c1441 Escherichia coli CFT073 hypothetical protein NP_753350.1 1348095 D 199310 CDS NP_753351.1 26247311 1035158 complement(1348100..1348333) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2366; hypothetical protein 1348333 1035158 c1442 Escherichia coli CFT073 hypothetical protein NP_753351.1 1348100 R 199310 CDS NP_753352.1 26247312 1035159 1348481..1348606 1 NC_004431.1 hypothetical protein 1348606 1035159 c1443 Escherichia coli CFT073 hypothetical protein NP_753352.1 1348481 D 199310 CDS NP_753353.1 26247313 1035160 1348728..1349237 1 NC_004431.1 Escherichia coli K-12 ortholog: b1548; Escherichia coli O157:H7 ortholog: z2365; prophage Qin DNA packaging protein NU1-like protein 1349237 1035160 c1444 Escherichia coli CFT073 prophage Qin DNA packaging protein NU1-like protein NP_753353.1 1348728 D 199310 CDS NP_753354.1 26247314 1035164 1349209..1351137 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2364; DNA packaging protein of prophage; terminase large subunit 1351137 1035164 c1445 Escherichia coli CFT073 DNA packaging protein of prophage; terminase large subunit NP_753354.1 1349209 D 199310 CDS NP_753355.1 26247315 1035165 1351121..1351327 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2363; DNA packaging protein of prophage 1351327 1035165 c1446 Escherichia coli CFT073 DNA packaging protein of prophage NP_753355.1 1351121 D 199310 CDS NP_753356.1 26247316 1035166 1351324..1352916 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2362; capsid protein of prophage 1352916 1035166 c1447 Escherichia coli CFT073 capsid protein of prophage NP_753356.1 1351324 D 199310 CDS NP_753357.1 26247317 1035168 1352906..1354411 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2361; capsid assembly protein of prophage 1354411 1035168 c1448 Escherichia coli CFT073 capsid assembly protein of prophage NP_753357.1 1352906 D 199310 CDS NP_753358.1 26247318 1035169 complement(1354427..1354798) 1 NC_004431.1 hypothetical protein 1354798 1035169 c1449 Escherichia coli CFT073 hypothetical protein NP_753358.1 1354427 R 199310 CDS NP_753359.1 26247319 1035170 1354448..1354795 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2360; capsid protein of prophage 1354795 1035170 c1450 Escherichia coli CFT073 capsid protein of prophage NP_753359.1 1354448 D 199310 CDS NP_753360.1 26247320 1035171 1354853..1355881 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1355881 1035171 c1451 Escherichia coli CFT073 capsid protein of prophage NP_753360.1 1354853 D 199310 CDS NP_753361.1 26247321 1035174 1355885..1356316 1 NC_004431.1 Residues 17 to 143 of 143 are 40.15 pct identical to residues 1 to 124 of 124 from SwissProt.40 : >sp|P36276|YG78_BPP21 Hypothetical 13.5 kDa protein in GP7-GP8 intergenic region; hypothetical protein 1356316 1035174 c1452 Escherichia coli CFT073 hypothetical protein NP_753361.1 1355885 D 199310 CDS NP_753362.1 26247322 1035175 1356309..1356662 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage 1356662 1035175 c1453 Escherichia coli CFT073 head-tail joining protein of prophage NP_753362.1 1356309 D 199310 CDS NP_753363.1 26247323 1035176 1356678..1357211 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0970; tail component of prophage 1357211 1035176 c1454 Escherichia coli CFT073 tail component of prophage NP_753363.1 1356678 D 199310 CDS NP_753364.1 26247324 1035177 1357208..1357603 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1893; tail component of prophage 1357603 1035177 c1455 Escherichia coli CFT073 tail component of prophage NP_753364.1 1357208 D 199310 CDS NP_753365.1 26247325 1035178 1357611..1358357 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3087; tail fiber component V of prophage 1358357 1035178 c1456 Escherichia coli CFT073 tail fiber component V of prophage NP_753365.1 1357611 D 199310 CDS NP_753366.1 26247326 1035179 complement(1358354..1359004) 1 NC_004431.1 hypothetical protein 1359004 1035179 c1457 Escherichia coli CFT073 hypothetical protein NP_753366.1 1358354 R 199310 CDS NP_753367.1 26247327 1035180 1358376..1358807 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2357; tail component of prophage 1358807 1035180 c1458 Escherichia coli CFT073 tail component of prophage NP_753367.1 1358376 D 199310 CDS NP_753368.1 26247328 1035181 1358834..1359247 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2356; tail component of prophage 1359247 1035181 c1459 Escherichia coli CFT073 tail component of prophage NP_753368.1 1358834 D 199310 CDS NP_753369.1 26247329 1035182 1359228..1361789 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2140; tail component of prophage 1361789 1035182 c1460 Escherichia coli CFT073 tail component of prophage NP_753369.1 1359228 D 199310 CDS NP_753370.1 26247330 1035183 1361786..1362115 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3083; tail fiber component M of prophage 1362115 1035183 c1461 Escherichia coli CFT073 tail fiber component M of prophage NP_753370.1 1361786 D 199310 CDS NP_753371.1 26247331 1035185 1362115..1362813 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2142; tail component of prophage 1362813 1035185 c1462 Escherichia coli CFT073 tail component of prophage NP_753371.1 1362115 D 199310 CDS NP_753372.1 26247332 1035186 complement(1362166..1362969) 1 NC_004431.1 hypothetical protein 1362969 1035186 c1463 Escherichia coli CFT073 hypothetical protein NP_753372.1 1362166 R 199310 CDS NP_753373.1 26247333 1035187 1362864..1363562 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3081; tail fiber component K of prophage 1363562 1035187 c1464 Escherichia coli CFT073 tail fiber component K of prophage NP_753373.1 1362864 D 199310 CDS NP_753374.1 26247334 1035188 1363526..1364140 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z6031; tail assembly protein of cryptic prophage 1364140 1035188 c1465 Escherichia coli CFT073 tail assembly protein of cryptic prophage NP_753374.1 1363526 D 199310 CDS NP_753375.1 26247335 1035189 1364484..1368176 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2145; tail component of prophage 1368176 1035189 c1466 Escherichia coli CFT073 tail component of prophage NP_753375.1 1364484 D 199310 CDS NP_753376.1 26247336 1035190 1368244..1368843 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z6028; Lom-like outer membrane protein of prophage 1368843 lomP 1035190 lomP Escherichia coli CFT073 Lom-like outer membrane protein of prophage NP_753376.1 1368244 D 199310 CDS NP_753377.1 26247337 1035192 1368995..1371058 1 NC_004431.1 Residues 4 to 248 of 687 are 29.38 pct identical to residues 196 to 438 of 973 from GenPept.129 : >gb|AAG56007.1|AE005333_4 (AE005333) membrane protein of prophage CP-933X [Escherichia coli O157:H7 EDL933]; hypothetical protein 1371058 1035192 c1468 Escherichia coli CFT073 hypothetical protein NP_753377.1 1368995 D 199310 CDS NP_753378.1 26247338 1035193 complement(1369339..1369503) 1 NC_004431.1 hypothetical protein 1369503 1035193 c1469 Escherichia coli CFT073 hypothetical protein NP_753378.1 1369339 R 199310 CDS NP_753379.1 26247339 1035194 1371055..1371333 1 NC_004431.1 hypothetical protein 1371333 1035194 c1470 Escherichia coli CFT073 hypothetical protein NP_753379.1 1371055 D 199310 CDS NP_753380.1 26247340 1035195 1371343..1371636 1 NC_004431.1 hypothetical protein 1371636 1035195 c1471 Escherichia coli CFT073 hypothetical protein NP_753380.1 1371343 D 199310 CDS NP_753381.1 26247341 1035196 complement(1371423..1371797) 1 NC_004431.1 hypothetical protein 1371797 1035196 c1472 Escherichia coli CFT073 hypothetical protein NP_753381.1 1371423 R 199310 CDS NP_753382.1 26247342 1035197 1371747..1371872 1 NC_004431.1 hypothetical protein 1371872 1035197 c1473 Escherichia coli CFT073 hypothetical protein NP_753382.1 1371747 D 199310 CDS NP_753383.1 26247343 1035198 complement(1371829..1372494) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0562; Escherichia coli O157:H7 ortholog: z1925; hypothetical protein 1372494 1035198 c1474 Escherichia coli CFT073 hypothetical protein NP_753383.1 1371829 R 199310 CDS NP_753384.1 26247344 1035199 1372554..1372820 1 NC_004431.1 Escherichia coli K-12 ortholog: b0563; Escherichia coli O157:H7 ortholog: z1926; hypothetical protein 1372820 ylcE 1035199 ylcE Escherichia coli CFT073 hypothetical protein NP_753384.1 1372554 D 199310 CDS NP_753385.1 26247345 1035200 complement(1373052..1373915) 1 NC_004431.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1373915 potB 1035200 potB Escherichia coli CFT073 spermidine/putrescine ABC transporter membrane protein NP_753385.1 1373052 R 199310 CDS NP_753386.1 26247346 1035201 complement(1373899..1375035) 1 NC_004431.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1375035 potA 1035201 potA Escherichia coli CFT073 putrescine/spermidine ABC transporter ATPase protein NP_753386.1 1373899 R 199310 CDS NP_753387.1 26247347 1035202 complement(1375014..1375265) 1 NC_004431.1 hypothetical protein 1375265 1035202 c1478 Escherichia coli CFT073 hypothetical protein NP_753387.1 1375014 R 199310 CDS NP_753388.1 26247348 1035204 1375240..1376511 1 NC_004431.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1376511 pepT 1035204 pepT Escherichia coli CFT073 peptidase T NP_753388.1 1375240 D 199310 CDS NP_753389.1 26247349 1035205 complement(1376560..1377690) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1128; Escherichia coli O157:H7 ortholog: z1833; hypothetical protein 1377690 ycfD 1035205 ycfD Escherichia coli CFT073 hypothetical protein NP_753389.1 1376560 R 199310 CDS NP_753390.1 26247350 1035208 complement(1377761..1378072) 1 NC_004431.1 hypothetical protein 1378072 1035208 c1481 Escherichia coli CFT073 hypothetical protein NP_753390.1 1377761 R 199310 CDS YP_004853808.1 347357911 1035209 complement(1377903..1378040) 1 NC_004431.1 hypothetical protein 1378040 1035209 c1482 Escherichia coli CFT073 hypothetical protein YP_004853808.1 1377903 R 199310 CDS NP_753392.1 26247352 1035210 1378215..1379159 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1835; integrase of prophage 1379159 1035210 c1483 Escherichia coli CFT073 integrase of prophage NP_753392.1 1378215 D 199310 CDS YP_004853809.1 347357930 1035211 1378670..1378936 1 NC_004431.1 hypothetical protein 1378936 1035211 c1484 Escherichia coli CFT073 hypothetical protein YP_004853809.1 1378670 D 199310 CDS NP_753394.1 26247354 1035212 complement(1379245..1379370) 1 NC_004431.1 hypothetical protein 1379370 1035212 c1485 Escherichia coli CFT073 hypothetical protein NP_753394.1 1379245 R 199310 CDS NP_753395.1 26247355 1035213 complement(1379395..1379535) 1 NC_004431.1 hypothetical protein 1379535 1035213 c1486 Escherichia coli CFT073 hypothetical protein NP_753395.1 1379395 R 199310 CDS NP_753396.1 26247356 1035214 1379766..1381052 1 NC_004431.1 Residues 114 to 279 of 428 are 55.36 pct identical to residues 20 to 196 of 247 from GenPept.129 : >dbj|BAB34999.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1381052 1035214 c1487 Escherichia coli CFT073 hypothetical protein NP_753396.1 1379766 D 199310 CDS NP_753397.1 26247357 1035215 1381049..1381279 1 NC_004431.1 Residues 3 to 61 of 76 are 52.54 pct identical to residues 2 to 60 of 63 from GenPept.129 : >dbj|BAB35002.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1381279 1035215 c1488 Escherichia coli CFT073 hypothetical protein NP_753397.1 1381049 D 199310 CDS NP_753398.1 26247358 1035217 complement(1381242..1381601) 1 NC_004431.1 hypothetical protein 1381601 1035217 c1489 Escherichia coli CFT073 hypothetical protein NP_753398.1 1381242 R 199310 CDS NP_753399.1 26247359 1035218 1381269..1381490 1 NC_004431.1 hypothetical protein 1381490 1035218 c1490 Escherichia coli CFT073 hypothetical protein NP_753399.1 1381269 D 199310 CDS NP_753400.1 26247360 1035220 1381465..1381704 1 NC_004431.1 hypothetical protein 1381704 1035220 c1491 Escherichia coli CFT073 hypothetical protein NP_753400.1 1381465 D 199310 CDS NP_753401.1 26247361 1035221 1381706..1381939 1 NC_004431.1 hypothetical protein 1381939 1035221 c1492 Escherichia coli CFT073 hypothetical protein NP_753401.1 1381706 D 199310 CDS NP_753402.1 26247362 1035222 1381945..1382244 1 NC_004431.1 Residues 1 to 99 of 99 are 82.82 pct identical to residues 1 to 99 of 99 from GenPept.129 : >dbj|BAB35004.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1382244 1035222 c1493 Escherichia coli CFT073 hypothetical protein NP_753402.1 1381945 D 199310 CDS NP_753403.1 26247363 1035223 complement(1381966..1382253) 1 NC_004431.1 hypothetical protein 1382253 1035223 c1494 Escherichia coli CFT073 hypothetical protein NP_753403.1 1381966 R 199310 CDS NP_753404.1 26247364 1035225 1382241..1383995 1 NC_004431.1 Residues 116 to 561 of 584 are 49.34 pct identical to residues 269 to 725 of 763 from GenPept.129 : >emb|CAC89726.1| (AJ414145) primase [Yersinia pestis]; hypothetical protein 1383995 1035225 c1495 Escherichia coli CFT073 hypothetical protein NP_753404.1 1382241 D 199310 CDS NP_753405.1 26247365 1035226 1384284..1384541 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1844; hypothetical protein 1384541 1035226 c1496 Escherichia coli CFT073 hypothetical protein NP_753405.1 1384284 D 199310 CDS NP_753406.1 26247366 1035228 1384538..1384948 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1845; single stranded DNA-binding protein of prophage 1384948 1035228 c1497 Escherichia coli CFT073 single stranded DNA-binding protein of prophage NP_753406.1 1384538 D 199310 CDS NP_753407.1 26247367 1035229 1385462..1385668 1 NC_004431.1 hypothetical protein 1385668 1035229 c1498 Escherichia coli CFT073 hypothetical protein NP_753407.1 1385462 D 199310 CDS NP_753408.1 26247368 1035230 1385668..1386723 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1386723 1035230 c1499 Escherichia coli CFT073 capsid protein of prophage NP_753408.1 1385668 D 199310 CDS NP_753409.1 26247369 1035231 1386735..1387070 1 NC_004431.1 Residues 6 to 105 of 111 are 36.63 pct identical to residues 13 to 110 of 115 from GenPept.129 : >gb|AAA32345.1| (M81255) capsid protein small subunit [Bacteriophage 21]; hypothetical protein 1387070 1035231 c1500 Escherichia coli CFT073 hypothetical protein NP_753409.1 1386735 D 199310 CDS NP_753410.1 26247370 1035235 1387083..1387496 1 NC_004431.1 hypothetical protein 1387496 1035235 c1501 Escherichia coli CFT073 hypothetical protein NP_753410.1 1387083 D 199310 CDS NP_753411.1 26247371 1035236 complement(1387524..1387706) 1 NC_004431.1 hypothetical protein 1387706 1035236 c1502 Escherichia coli CFT073 hypothetical protein NP_753411.1 1387524 R 199310 CDS NP_753412.1 26247372 1035237 1387752..1388093 1 NC_004431.1 hypothetical protein 1388093 1035237 c1503 Escherichia coli CFT073 hypothetical protein NP_753412.1 1387752 D 199310 CDS NP_753413.1 26247373 1035238 1388123..1388284 1 NC_004431.1 hypothetical protein 1388284 1035238 c1504 Escherichia coli CFT073 hypothetical protein NP_753413.1 1388123 D 199310 CDS NP_753414.1 26247374 1035240 1388373..1388654 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1855; hypothetical protein 1388654 1035240 c1505 Escherichia coli CFT073 hypothetical protein NP_753414.1 1388373 D 199310 CDS NP_753415.1 26247375 1035241 complement(1388397..1388834) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1856; hypothetical protein 1388834 1035241 c1506 Escherichia coli CFT073 hypothetical protein NP_753415.1 1388397 R 199310 CDS NP_753416.1 26247376 1035242 1388812..1388952 1 NC_004431.1 hypothetical protein 1388952 1035242 c1507 Escherichia coli CFT073 hypothetical protein NP_753416.1 1388812 D 199310 CDS NP_753417.1 26247377 1035243 complement(1389209..1390669) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1129; Escherichia coli O157:H7 ortholog: z1858; sensor protein PhoQ 1390669 phoQ 1035243 phoQ Escherichia coli CFT073 sensor protein PhoQ NP_753417.1 1389209 R 199310 CDS NP_753418.1 26247378 1035244 complement(1390669..1391340) 1 NC_004431.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1391340 phoP 1035244 phoP Escherichia coli CFT073 DNA-binding transcriptional regulator PhoP NP_753418.1 1390669 R 199310 CDS NP_753419.1 26247379 1035246 complement(1391510..1392880) 1 NC_004431.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1392880 purB 1035246 purB Escherichia coli CFT073 adenylosuccinate lyase NP_753419.1 1391510 R 199310 CDS NP_753420.1 26247380 1035247 complement(1392884..1393531) 1 NC_004431.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1393531 ycfC 1035247 ycfC Escherichia coli CFT073 hypothetical protein NP_753420.1 1392884 R 199310 CDS NP_753421.2 161486247 1035248 complement(1393561..1394667) 1 NC_004431.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1394667 mnmA 1035248 mnmA Escherichia coli CFT073 tRNA-specific 2-thiouridylase MnmA NP_753421.2 1393561 R 199310 CDS NP_753422.1 26247382 1035249 complement(1394721..1395182) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1134; Escherichia coli O157:H7 ortholog: z1863; Nudix hydrolase ymfB 1395182 1035249 c1513 Escherichia coli CFT073 Nudix hydrolase ymfB NP_753422.1 1394721 R 199310 CDS NP_753423.1 26247383 1035250 complement(1395370..1395726) 1 NC_004431.1 Residues 1 to 112 of 118 are 98.21 pct identical to residues 31 to 142 of 207 from GenPept.129 : >gb|AAG55961.1|AE005329_5 (AE005329) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 1395726 1035250 c1514 Escherichia coli CFT073 hypothetical protein NP_753423.1 1395370 R 199310 CDS NP_753424.1 26247384 1035251 1395766..1395888 1 NC_004431.1 hypothetical protein 1395888 1035251 c1515 Escherichia coli CFT073 hypothetical protein NP_753424.1 1395766 D 199310 CDS NP_753425.1 26247385 1035253 complement(1395934..1397115) 1 NC_004431.1 hypothetical protein 1397115 1035253 c1516 Escherichia coli CFT073 hypothetical protein NP_753425.1 1395934 R 199310 CDS NP_753426.1 26247386 1035254 1396018..1397268 1 NC_004431.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1397268 icdA 1035254 icdA Escherichia coli CFT073 isocitrate dehydrogenase NP_753426.1 1396018 D 199310 CDS NP_753427.1 26247387 1035255 1397313..1397456 1 NC_004431.1 hypothetical protein 1397456 1035255 c1518 Escherichia coli CFT073 hypothetical protein NP_753427.1 1397313 D 199310 CDS NP_753428.1 26247388 1035256 complement(1397370..1398512) 1 NC_004431.1 Int(Lambda); Escherichia coli K-12 ortholog: b1140; Escherichia coli O157:H7 ortholog: z1866; prophage lambda integrase 1398512 1035256 c1519 Escherichia coli CFT073 prophage lambda integrase NP_753428.1 1397370 R 199310 CDS NP_753429.1 26247389 1035257 1398656..1398982 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 1398982 1035257 c1520 Escherichia coli CFT073 hypothetical protein NP_753429.1 1398656 D 199310 CDS NP_753430.1 26247390 1035258 1398979..1399869 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 1399869 1035258 c1521 Escherichia coli CFT073 transposase IS629 NP_753430.1 1398979 D 199310 CDS NP_753431.1 26247391 1035259 complement(1400191..1400430) 1 NC_004431.1 Residues 1 to 79 of 79 are 40.00 pct identical to residues 42 to 121 of 121 from GenPept.129 : >emb|CAC83521.1| (AJ298298) hypothetical protein [Bacteriophage P27]; hypothetical protein 1400430 1035259 c1522 Escherichia coli CFT073 hypothetical protein NP_753431.1 1400191 R 199310 CDS NP_753432.1 26247392 1035260 complement(1400456..1400824) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1428; hypothetical protein 1400824 1035260 c1523 Escherichia coli CFT073 hypothetical protein NP_753432.1 1400456 R 199310 CDS NP_753433.1 26247393 1035261 complement(1400733..1401473) 1 NC_004431.1 Residues 1 to 201 of 246 are 49.42 pct identical to residues 1 to 257 of 317 from SwissProt.40 : >sp|Q03544|VEAA_BPP22 Eaa protein; hypothetical protein 1401473 1035261 c1524 Escherichia coli CFT073 hypothetical protein NP_753433.1 1400733 R 199310 CDS NP_753434.1 26247394 1035263 complement(1401470..1401721) 1 NC_004431.1 Residues 11 to 82 of 83 are 87.50 pct identical to residues 21 to 92 of 95 from GenPept.129 : >dbj|BAB87939.1| (AP004402) hypothetical protein [Stx2 converting bacteriophage I]; hypothetical protein 1401721 1035263 c1525 Escherichia coli CFT073 hypothetical protein NP_753434.1 1401470 R 199310 CDS NP_753435.1 26247395 1035264 complement(1401681..1402241) 1 NC_004431.1 Residues 35 to 121 of 186 are 81.60 pct identical to residues 94 to 180 of 187 from GenPept.129 : >gb|AAG57028.1|AE005422_3 (AE005422) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein 1402241 1035264 c1526 Escherichia coli CFT073 hypothetical protein NP_753435.1 1401681 R 199310 CDS NP_753436.1 26247396 1035266 complement(1402232..1402507) 1 NC_004431.1 Residues 8 to 57 of 91 are 77.99 pct identical to residues 1 to 50 of 118 from GenPept.129 : >gb|AAG57254.1|AE005444_4 (AE005444) unknown protein encoded within prophage CP-933V [Escherichia coli O157:H7 EDL933]; hypothetical protein 1402507 1035266 c1527 Escherichia coli CFT073 hypothetical protein NP_753436.1 1402232 R 199310 CDS NP_753437.1 26247397 1035268 complement(1402488..1402817) 1 NC_004431.1 Residues 57 to 109 of 109 are 71.69 pct identical to residues 98 to 150 of 151 from GenPept.129 : >dbj|BAB12619.1| (AP002527) ycgB [Escherichia coli]; hypothetical protein 1402817 1035268 c1528 Escherichia coli CFT073 hypothetical protein NP_753437.1 1402488 R 199310 CDS NP_753438.1 26247398 1035269 complement(1402870..1403625) 1 NC_004431.1 Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 1403625 1035269 c1529 Escherichia coli CFT073 hypothetical protein NP_753438.1 1402870 R 199310 CDS NP_753439.1 26247399 1035270 complement(1403622..1405121) 1 NC_004431.1 Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein 1405121 1035270 c1530 Escherichia coli CFT073 hypothetical protein NP_753439.1 1403622 R 199310 CDS NP_753440.1 26247400 1035271 complement(1405210..1405668) 1 NC_004431.1 Residues 1 to 124 of 152 are 85.48 pct identical to residues 1 to 124 of 238 from GenPept.129 : >gb|AAK28855.1|AF335538_7 (AF335538) unknown [Bacteriophage HK620]; hypothetical protein 1405668 1035271 c1531 Escherichia coli CFT073 hypothetical protein NP_753440.1 1405210 R 199310 CDS NP_753441.1 26247401 1035273 complement(1405985..1406266) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3369; hypothetical protein 1406266 1035273 c1532 Escherichia coli CFT073 hypothetical protein NP_753441.1 1405985 R 199310 CDS NP_753442.1 26247402 1035274 complement(1406441..1406629) 1 NC_004431.1 Residues 3 to 62 of 62 are 96.66 pct identical to residues 1 to 60 of 60 from GenPept.129 : >gb|AAL02051.1| (AY048746) orf60a protein [Red recombinase plasmid pKD46]; hypothetical protein 1406629 1035274 c1533 Escherichia coli CFT073 hypothetical protein NP_753442.1 1406441 R 199310 CDS NP_753443.1 26247403 1035275 complement(1406620..1407300) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0951; exonuclease encoded by prophage 1407300 1035275 c1534 Escherichia coli CFT073 exonuclease encoded by prophage NP_753443.1 1406620 R 199310 CDS NP_753444.1 26247404 1035276 1406629..1406940 1 NC_004431.1 Residues 1 to 90 of 103 are 94.44 pct identical to residues 46 to 135 of 186 from MG1655 : b0538; hypothetical protein 1406940 1035276 c1535 Escherichia coli CFT073 hypothetical protein NP_753444.1 1406629 D 199310 CDS NP_753445.1 26247405 1035278 complement(1407297..1408082) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3366; recombination protein Bet of prophage 1408082 1035278 c1536 Escherichia coli CFT073 recombination protein Bet of prophage NP_753445.1 1407297 R 199310 CDS NP_753446.1 26247406 1035279 complement(1408088..1408384) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1438; host-nuclease inhibitor protein Gam of bacteriphage 1408384 gamW 1035279 gamW Escherichia coli CFT073 host-nuclease inhibitor protein Gam of bacteriphage NP_753446.1 1408088 R 199310 CDS NP_753447.1 26247407 1035281 complement(1408353..1408505) 1 NC_004431.1 Residues 1 to 50 of 50 are 95.99 pct identical to residues 1 to 50 of 50 from GenPept.129 : >dbj|BAB36422.1| (AP002560) host-nuclease inhibitor protein gam [Escherichia coli O157:H7]; hypothetical protein 1408505 1035281 c1538 Escherichia coli CFT073 hypothetical protein NP_753447.1 1408353 R 199310 CDS NP_753448.1 26247408 1035282 complement(1408460..1408603) 1 NC_004431.1 Residues 1 to 47 of 47 are 97.87 pct identical to residues 1 to 47 of 47 from GenPept.129 : >gb|AAA96572.1| (J02459) kil(host-killing;54) [bacteriophage lambda]; hypothetical protein 1408603 1035282 c1539 Escherichia coli CFT073 hypothetical protein NP_753448.1 1408460 R 199310 CDS NP_753449.1 26247409 1035283 complement(1408572..1408736) 1 NC_004431.1 Residues 1 to 54 of 54 are 98.14 pct identical to residues 1 to 54 of 54 from SwissProt.40 : >sp|P03044|RPC3_LAMBD REGULATORY PROTEIN CIII; lambda regulatory protein CIII 1408736 1035283 c1540 Escherichia coli CFT073 lambda regulatory protein CIII NP_753449.1 1408572 R 199310 CDS NP_753450.1 26247410 1035285 complement(1408809..1409177) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3363; single-stranded DNA binding protein of prophage 1409177 1035285 c1541 Escherichia coli CFT073 single-stranded DNA binding protein of prophage NP_753450.1 1408809 R 199310 CDS NP_753451.1 26247411 1035287 complement(1409360..1409560) 1 NC_004431.1 Residues 1 to 66 of 66 are 98.48 pct identical to residues 1 to 66 of 66 from SwissProt.40 : >sp|P03703|VRAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein); lambda ant-restriction protein 1409560 1035287 c1542 Escherichia coli CFT073 lambda ant-restriction protein NP_753451.1 1409360 R 199310 CDS NP_753452.1 26247412 1035288 1409774..1410355 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3362; superinfection exclusion protein B of prophage 1410355 1035288 c1543 Escherichia coli CFT073 superinfection exclusion protein B of prophage NP_753452.1 1409774 D 199310 CDS NP_753453.1 26247413 1035289 complement(1411081..1411833) 1 NC_004431.1 hypothetical protein 1411833 1035289 c1544 Escherichia coli CFT073 hypothetical protein NP_753453.1 1411081 R 199310 CDS NP_753454.1 26247414 1035291 complement(1411830..1412387) 1 NC_004431.1 hypothetical protein 1412387 1035291 c1545 Escherichia coli CFT073 hypothetical protein NP_753454.1 1411830 R 199310 CDS NP_753455.1 26247415 1035292 complement(1412427..1412849) 1 NC_004431.1 Residues 1 to 140 of 140 are 97.14 pct identical to residues 30 to 169 of 169 from GenPept.129 : >dbj|BAA84306.1| (AP000363) similar to CI repressor of bacteriophage lambda [Bacteriophage VT2-Sa]; repressor protein 1412849 1035292 c1546 Escherichia coli CFT073 repressor protein NP_753455.1 1412427 R 199310 CDS NP_753456.1 26247416 1035294 1413040..1413420 1 NC_004431.1 Residues 56 to 126 of 126 are 100.00 pct identical to residues 1 to 71 of 71 from GenPept.129 : >dbj|BAA84307.1| (AP000363) similar to C2 of bacteriophage L [Bacteriophage VT2-Sa]; hypothetical protein 1413420 1035294 c1547 Escherichia coli CFT073 hypothetical protein NP_753456.1 1413040 D 199310 CDS NP_753457.1 26247417 1035295 1413562..1413858 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1449; regulatory protein CII of bacteriophage 1413858 1035295 c1548 Escherichia coli CFT073 regulatory protein CII of bacteriophage NP_753457.1 1413562 D 199310 CDS NP_753458.1 26247418 1035296 1413891..1414790 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1450; replication protein O of bacteriophage 1414790 1035296 c1549 Escherichia coli CFT073 replication protein O of bacteriophage NP_753458.1 1413891 D 199310 CDS NP_753459.1 26247419 1035297 1414787..1415488 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1451; replication protein P of bacteriophage 1415488 1035297 c1550 Escherichia coli CFT073 replication protein P of bacteriophage NP_753459.1 1414787 D 199310 CDS NP_753460.1 26247420 1035300 1415485..1415775 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3354; exclusion protein ren of prophage 1415775 1035300 c1551 Escherichia coli CFT073 exclusion protein ren of prophage NP_753460.1 1415485 D 199310 CDS NP_753461.1 26247421 1035301 1415867..1416193 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 1416193 1035301 c1552 Escherichia coli CFT073 hypothetical protein NP_753461.1 1415867 D 199310 CDS NP_753462.1 26247422 1035302 1416190..1417080 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 1417080 1035302 c1553 Escherichia coli CFT073 transposase IS629 NP_753462.1 1416190 D 199310 CDS NP_753463.1 26247423 1035303 1417162..1417602 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3351; hypothetical protein 1417602 1035303 c1554 Escherichia coli CFT073 hypothetical protein NP_753463.1 1417162 D 199310 CDS NP_753464.1 26247424 1035304 1417569..1418126 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1454; DNA N-6-adenine-methyltransferase of bacteriophage 1418126 1035304 c1555 Escherichia coli CFT073 DNA N-6-adenine-methyltransferase of bacteriophage NP_753464.1 1417569 D 199310 CDS NP_753465.1 26247425 1035305 1418302..1418643 1 NC_004431.1 Residues 1 to 113 of 113 are 61.01 pct identical to residues 3 to 112 of 112 from SwissProt.40 : >sp|Q38665|NINX_BPP22 protein ninX; hypothetical protein 1418643 1035305 c1556 Escherichia coli CFT073 hypothetical protein NP_753465.1 1418302 D 199310 CDS NP_753466.1 26247426 1035306 1418850..1419212 1 NC_004431.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1419212 rus 1035306 rus Escherichia coli CFT073 endodeoxyribonuclease RUS NP_753466.1 1418850 D 199310 CDS NP_753467.1 26247427 1035307 1419209..1419349 1 NC_004431.1 Residues 1 to 46 of 46 are 95.65 pct identical to residues 1 to 46 of 46 from SwissProt.40 : >sp|Q47272|YLCG_ECOLI Hypothetical protein ylcG in lambdoid DLP12 prophage region; hypothetical protein 1419349 1035307 c1558 Escherichia coli CFT073 hypothetical protein NP_753467.1 1419209 D 199310 CDS NP_753468.1 26247428 1035308 1419420..1419818 1 NC_004431.1 Escherichia coli K-12 ortholog: b0551; Escherichia coli O157:H7 ortholog: z1786; lambdoid prophage DLP12 antitermination protein Q 1419818 ybcQ 1035308 ybcQ Escherichia coli CFT073 lambdoid prophage DLP12 antitermination protein Q NP_753468.1 1419420 D 199310 CDS NP_753469.1 26247429 1035311 complement(1420007..1421149) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; outer membrane porin protein nmpC 1421149 nmpC 1035311 nmpC Escherichia coli CFT073 outer membrane porin protein nmpC NP_753469.1 1420007 R 199310 CDS NP_753470.1 26247430 1035312 1421678..1421893 1 NC_004431.1 Escherichia coli K-12 ortholog: b0554; Escherichia coli O157:H7 ortholog: z3340; lambdoid prophage DLP12 lysis protein S 1421893 1035312 c1561 Escherichia coli CFT073 lambdoid prophage DLP12 lysis protein S NP_753470.1 1421678 D 199310 CDS NP_753471.1 26247431 1035313 1421893..1422390 1 NC_004431.1 Escherichia coli K-12 ortholog: b0555; Escherichia coli O157:H7 ortholog: z0960; lysozyme from lambdoid prophage DLP12 1422390 ybcS 1035313 ybcS Escherichia coli CFT073 lysozyme from lambdoid prophage DLP12 NP_753471.1 1421893 D 199310 CDS NP_753472.1 26247432 1035314 1422375..1422848 1 NC_004431.1 Escherichia coli K-12 ortholog: b0556; Escherichia coli O157:H7 ortholog: z1473; Rz endopeptidase from lambdoid prophage DLP12 1422848 1035314 c1563 Escherichia coli CFT073 Rz endopeptidase from lambdoid prophage DLP12 NP_753472.1 1422375 D 199310 CDS NP_753473.1 26247433 1035316 complement(1422880..1423221) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0557; Escherichia coli O157:H7 ortholog: z1878; lambdoid prophage DLP12 Bor-like protein 1423221 ybcU 1035316 ybcU Escherichia coli CFT073 lambdoid prophage DLP12 Bor-like protein NP_753473.1 1422880 R 199310 CDS NP_753474.1 26247434 1035317 1423600..1423980 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1799; tonB-like membrane protein encoded within prophage 1423980 1035317 c1565 Escherichia coli CFT073 tonB-like membrane protein encoded within prophage NP_753474.1 1423600 D 199310 CDS NP_753475.1 26247435 1035318 complement(1423628..1423780) 1 NC_004431.1 hypothetical protein 1423780 1035318 c1566 Escherichia coli CFT073 hypothetical protein NP_753475.1 1423628 R 199310 CDS NP_753476.1 26247436 1035319 1424187..1424369 1 NC_004431.1 hypothetical protein 1424369 1035319 c1567 Escherichia coli CFT073 hypothetical protein NP_753476.1 1424187 D 199310 CDS NP_753477.1 26247437 1035320 1424932..1425480 1 NC_004431.1 Escherichia coli K-12 ortholog: b1548; Escherichia coli O157:H7 ortholog: z1882; prophage Qin DNA packaging protein NU1-like protein 1425480 nohA 1035320 nohA Escherichia coli CFT073 prophage Qin DNA packaging protein NU1-like protein NP_753477.1 1424932 D 199310 CDS NP_753478.1 26247438 1035321 1425428..1427380 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2364; DNA packaging protein of prophage; terminase large subunit 1427380 1035321 c1569 Escherichia coli CFT073 DNA packaging protein of prophage; terminase large subunit NP_753478.1 1425428 D 199310 CDS NP_753479.1 26247439 1035323 1427364..1427570 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2363; DNA packaging protein of prophage 1427570 1035323 c1570 Escherichia coli CFT073 DNA packaging protein of prophage NP_753479.1 1427364 D 199310 CDS NP_753480.1 26247440 1035324 1427567..1429159 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2362; capsid protein of prophage 1429159 1035324 c1571 Escherichia coli CFT073 capsid protein of prophage NP_753480.1 1427567 D 199310 CDS NP_753481.1 26247441 1035325 1429149..1430654 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2361; capsid assembly protein of prophage 1430654 1035325 c1572 Escherichia coli CFT073 capsid assembly protein of prophage NP_753481.1 1429149 D 199310 CDS NP_753482.1 26247442 1035326 complement(1430670..1431041) 1 NC_004431.1 hypothetical protein 1431041 1035326 c1573 Escherichia coli CFT073 hypothetical protein NP_753482.1 1430670 R 199310 CDS NP_753483.1 26247443 1035327 1430691..1431038 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2360; capsid protein of prophage 1431038 1035327 c1574 Escherichia coli CFT073 capsid protein of prophage NP_753483.1 1430691 D 199310 CDS NP_753484.1 26247444 1035328 1431096..1432124 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1432124 1035328 c1575 Escherichia coli CFT073 capsid protein of prophage NP_753484.1 1431096 D 199310 CDS NP_753485.1 26247445 1035329 1432128..1432550 1 NC_004431.1 Residues 17 to 140 of 140 are 100.00 pct identical to residues 1 to 124 of 124 from SwissProt.40 : >sp|P36276|YG78_BPP21 Hypothetical 13.5 kDa protein in GP7-GP8 intergenic region; hypothetical protein 1432550 1035329 c1576 Escherichia coli CFT073 hypothetical protein NP_753485.1 1432128 D 199310 CDS NP_753486.1 26247446 1035332 1432522..1432896 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage 1432896 1035332 c1577 Escherichia coli CFT073 head-tail joining protein of prophage NP_753486.1 1432522 D 199310 CDS NP_753487.1 26247447 1035333 1432908..1433486 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3089; tail fiber component Z of prophage 1433486 1035333 c1578 Escherichia coli CFT073 tail fiber component Z of prophage NP_753487.1 1432908 D 199310 CDS NP_753488.1 26247448 1035334 1433483..1433878 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1893; tail component of prophage 1433878 1035334 c1579 Escherichia coli CFT073 tail component of prophage NP_753488.1 1433483 D 199310 CDS NP_753489.1 26247449 1035335 1433856..1434020 1 NC_004431.1 Residues 1 to 53 of 54 are 96.22 pct identical to residues 1 to 53 of 256 from GenPept.129 : >gb|AAG55990.1|AE005331_3 (AE005331) tail component of prophage CP-933X [Escherichia coli O157:H7 EDL933]; tail protein 1434020 1035335 c1580 Escherichia coli CFT073 tail protein NP_753489.1 1433856 D 199310 CDS NP_753490.1 26247450 1035336 complement(1434181..1434612) 1 NC_004431.1 hypothetical protein 1434612 1035336 c1581 Escherichia coli CFT073 hypothetical protein NP_753490.1 1434181 R 199310 CDS NP_753491.1 26247451 1035339 1434638..1435060 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1895; tail component of prophage 1435060 1035339 c1583 Escherichia coli CFT073 tail component of prophage NP_753491.1 1434638 D 199310 CDS NP_753492.1 26247452 1035340 1435042..1435476 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1896; tail component of prophage 1435476 1035340 c1584 Escherichia coli CFT073 tail component of prophage NP_753492.1 1435042 D 199310 CDS NP_753493.1 26247453 1035341 1435469..1438030 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2140; tail component of prophage 1438030 1035341 c1585 Escherichia coli CFT073 tail component of prophage NP_753493.1 1435469 D 199310 CDS NP_753494.1 26247454 1035342 complement(1438260..1438910) 1 NC_004431.1 hypothetical protein 1438910 1035342 c1586 Escherichia coli CFT073 hypothetical protein NP_753494.1 1438260 R 199310 CDS NP_753495.1 26247455 1035343 1438356..1439054 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0977; tail component of prophage 1439054 1035343 c1587 Escherichia coli CFT073 tail component of prophage NP_753495.1 1438356 D 199310 CDS NP_753496.1 26247456 1035344 1439060..1439803 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0978; tail component of prophage 1439803 1035344 c1588 Escherichia coli CFT073 tail component of prophage NP_753496.1 1439060 D 199310 CDS NP_753497.1 26247457 1035345 1439740..1440372 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0979; tail component of prophage 1440372 1035345 c1589 Escherichia coli CFT073 tail component of prophage NP_753497.1 1439740 D 199310 CDS NP_753498.1 26247458 1035348 1440433..1443915 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2145; tail component of prophage 1443915 1035348 c1590 Escherichia coli CFT073 tail component of prophage NP_753498.1 1440433 D 199310 CDS NP_753499.1 26247459 1035349 1443968..1445635 1 NC_004431.1 Residues 116 to 226 of 555 are 36.44 pct identical to residues 389 to 506 of 1122 from GenPept.129 : >gb|AAC74454.1| (AE000234) membrane protein [Escherichia coli K12]; hypothetical protein 1445635 1035349 c1591 Escherichia coli CFT073 hypothetical protein NP_753499.1 1443968 D 199310 CDS NP_753500.1 26247460 1035350 complement(1444336..1444590) 1 NC_004431.1 Residues 3 to 82 of 84 are 48.23 pct identical to residues 65 to 149 of 206 from GenPept.129 : >gb|AAA96556.1| (J02459) orf206b [bacteriophage lambda]; hypothetical protein 1444590 1035350 c1592 Escherichia coli CFT073 hypothetical protein NP_753500.1 1444336 R 199310 CDS NP_753501.1 26247461 1035351 1445744..1446034 1 NC_004431.1 hypothetical protein 1446034 1035351 c1593 Escherichia coli CFT073 hypothetical protein NP_753501.1 1445744 D 199310 CDS NP_753502.1 26247462 1035354 1446031..1446309 1 NC_004431.1 hypothetical protein 1446309 1035354 c1594 Escherichia coli CFT073 hypothetical protein NP_753502.1 1446031 D 199310 CDS NP_753503.1 26247463 1035355 1446322..1446615 1 NC_004431.1 hypothetical protein 1446615 1035355 c1595 Escherichia coli CFT073 hypothetical protein NP_753503.1 1446322 D 199310 CDS NP_753504.1 26247464 1035356 complement(1446337..1446777) 1 NC_004431.1 hypothetical protein 1446777 1035356 c1596 Escherichia coli CFT073 hypothetical protein NP_753504.1 1446337 R 199310 CDS NP_753505.1 26247465 1035357 complement(1446707..1447564) 1 NC_004431.1 Residues 1 to 272 of 285 are 53.30 pct identical to residues 4 to 275 of 297 from SwissProt.40 : >sp|Q56955|YFED_YERPE Chelated iron transport system membrane protein yfeD; SitD protein 1447564 sitD 1035357 sitD Escherichia coli CFT073 SitD protein NP_753505.1 1446707 R 199310 CDS NP_753506.1 26247466 1035358 complement(1447561..1448418) 1 NC_004431.1 Residues 1 to 276 of 285 are 65.94 pct identical to residues 2 to 277 of 294 from SwissProt.40 : >sp|Q56954|YFEC_YERPE Chelated iron transport system membrane protein yfeC; SitC protein 1448418 sitC 1035358 sitC Escherichia coli CFT073 SitC protein NP_753506.1 1447561 R 199310 CDS NP_753507.1 26247467 1035359 complement(1448415..1449242) 1 NC_004431.1 Residues 7 to 263 of 275 are 62.03 pct identical to residues 11 to 276 of 296 from SwissProt.40 : >sp|Q56953|YFEB_YERPE Chelated iron transport system membrane protein yfeB; SitB protein 1449242 sitB 1035359 sitB Escherichia coli CFT073 SitB protein NP_753507.1 1448415 R 199310 CDS NP_753508.1 26247468 1035361 complement(1449293..1450150) 1 NC_004431.1 Residues 2 to 263 of 285 are 62.97 pct identical to residues 3 to 257 of 293 from SwissProt.40 : >sp|Q57449|Y362_HAEIN PERIPLASMIC IRON-BINDING PROTEIN HI0362 PRECURSOR; SitA protein 1450150 sitA 1035361 sitA Escherichia coli CFT073 SitA protein NP_753508.1 1449293 R 199310 CDS NP_753509.1 26247469 1035363 1450837..1451607 1 NC_004431.1 hypothetical protein 1451607 1035363 c1601 Escherichia coli CFT073 hypothetical protein NP_753509.1 1450837 D 199310 CDS NP_753510.1 26247470 1035364 1452079..1452231 1 NC_004431.1 Residues 1 to 50 of 50 are 98.00 pct identical to residues 5 to 54 of 54 from GenPept.129 : >gb|AAC48887.1| (AF017626) isocitrate dehydrogenase [Bacteriophage 21]; hypothetical protein 1452231 1035364 c1602 Escherichia coli CFT073 hypothetical protein NP_753510.1 1452079 D 199310 CDS NP_753511.1 26247471 1035365 complement(1452493..1452897) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1161; Escherichia coli O157:H7 ortholog: z1879; hypothetical protein 1452897 ycgX 1035365 ycgX Escherichia coli CFT073 hypothetical protein NP_753511.1 1452493 R 199310 CDS NP_753512.1 26247472 1035366 complement(1453118..1453849) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1162; Escherichia coli O157:H7 ortholog: z3376; transcriptional regulator YcgE 1453849 ycgE 1035366 ycgE Escherichia coli CFT073 transcriptional regulator YcgE NP_753512.1 1453118 R 199310 CDS NP_753513.1 26247473 1035367 complement(1453759..1453911) 1 NC_004431.1 hypothetical protein 1453911 1035367 c1605 Escherichia coli CFT073 hypothetical protein NP_753513.1 1453759 R 199310 CDS NP_753514.1 26247474 1035370 complement(1454054..1455343) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1163; hypothetical protein 1455343 ycgF 1035370 ycgF Escherichia coli CFT073 hypothetical protein NP_753514.1 1454054 R 199310 CDS NP_753515.1 26247475 1035371 1455579..1455815 1 NC_004431.1 Escherichia coli K-12 ortholog: b1164; hypothetical protein 1455815 ycgZ 1035371 ycgZ Escherichia coli CFT073 hypothetical protein NP_753515.1 1455579 D 199310 CDS NP_753516.1 26247476 1035372 complement(1455792..1455965) 1 NC_004431.1 hypothetical protein 1455965 1035372 c1608 Escherichia coli CFT073 hypothetical protein NP_753516.1 1455792 R 199310 CDS NP_753517.1 26247477 1035374 1456159..1456425 1 NC_004431.1 Escherichia coli K-12 ortholog: b1166; hypothetical protein 1456425 ymgB 1035374 ymgB Escherichia coli CFT073 hypothetical protein NP_753517.1 1456159 D 199310 CDS NP_753518.1 26247478 1035375 1457126..1457977 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0403; hypothetical protein 1457977 1035375 c1610 Escherichia coli CFT073 hypothetical protein NP_753518.1 1457126 D 199310 CDS NP_753519.1 26247479 1035376 1458073..1458327 1 NC_004431.1 Residues 13 to 83 of 84 are 98.59 pct identical to residues 1 to 71 of 72 from SwissProt.40 : >sp|P58034|YMGF_ECOLI Hypothetical protein ymgF; hypothetical protein 1458327 1035376 c1611 Escherichia coli CFT073 hypothetical protein NP_753519.1 1458073 D 199310 CDS NP_753520.1 26247480 1035380 1459716..1460243 1 NC_004431.1 Residues 1 to 47 of 175 are 97.87 pct identical to residues 42 to 88 of 338 from MG1655 : b1170; hypothetical protein 1460243 1035380 c1615 Escherichia coli CFT073 hypothetical protein NP_753520.1 1459716 D 199310 CDS NP_753521.1 26247481 1035381 complement(1460301..1460636) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1171; hypothetical protein 1460636 ymgD 1035381 ymgD Escherichia coli CFT073 hypothetical protein NP_753521.1 1460301 R 199310 CDS NP_753522.1 26247482 1035382 complement(1460640..1460984) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1172; hypothetical protein 1460984 1035382 c1617 Escherichia coli CFT073 hypothetical protein NP_753522.1 1460640 R 199310 CDS NP_753523.1 26247483 1035383 complement(1460986..1461159) 1 NC_004431.1 hypothetical protein 1461159 1035383 c1618 Escherichia coli CFT073 hypothetical protein NP_753523.1 1460986 R 199310 CDS NP_753524.1 26247484 1035384 1461577..1461903 1 NC_004431.1 Residues 1 to 108 of 108 are 94.44 pct identical to residues 1462 to 1569 of 1569 from MG1655 : b2647; hypothetical protein 1461903 1035384 c1619 Escherichia coli CFT073 hypothetical protein NP_753524.1 1461577 D 199310 CDS NP_753525.1 26247485 1035385 1461949..1462134 1 NC_004431.1 hypothetical protein 1462134 1035385 c1620 Escherichia coli CFT073 hypothetical protein NP_753525.1 1461949 D 199310 CDS NP_753526.1 26247486 1035386 complement(1462276..1462542) 1 NC_004431.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1462542 minE 1035386 minE Escherichia coli CFT073 cell division topological specificity factor MinE NP_753526.1 1462276 R 199310 CDS NP_753527.1 26247487 1035387 complement(1462546..1463358) 1 NC_004431.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1463358 minD 1035387 minD Escherichia coli CFT073 cell division inhibitor MinD NP_753527.1 1462546 R 199310 CDS NP_753528.2 161486246 1035388 complement(1463382..1464077) 1 NC_004431.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1464077 minC 1035388 minC Escherichia coli CFT073 septum formation inhibitor NP_753528.2 1463382 R 199310 CDS NP_753529.1 26247489 1035389 1464217..1464444 1 NC_004431.1 hypothetical protein 1464444 1035389 c1624 Escherichia coli CFT073 hypothetical protein NP_753529.1 1464217 D 199310 CDS NP_753530.1 26247490 1035390 1464597..1464965 1 NC_004431.1 Escherichia coli K-12 ortholog: b1177; Escherichia coli O157:H7 ortholog: z1939; hypothetical protein 1464965 ycgJ 1035390 ycgJ Escherichia coli CFT073 hypothetical protein NP_753530.1 1464597 D 199310 CDS NP_753531.1 26247491 1035391 complement(1465085..1465486) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1178; Escherichia coli O157:H7 ortholog: z1940; hypothetical protein 1465486 ycgK 1035391 ycgK Escherichia coli CFT073 hypothetical protein NP_753531.1 1465085 R 199310 CDS NP_753532.1 26247492 1035392 1465695..1466021 1 NC_004431.1 Escherichia coli K-12 ortholog: b1179; Escherichia coli O157:H7 ortholog: z1941; hypothetical protein 1466021 ycgL 1035392 ycgL Escherichia coli CFT073 hypothetical protein NP_753532.1 1465695 D 199310 CDS NP_753533.1 26247493 1035394 1466093..1466752 1 NC_004431.1 Escherichia coli K-12 ortholog: b1180; Escherichia coli O157:H7 ortholog: z1942; hypothetical protein 1466752 1035394 c1628 Escherichia coli CFT073 hypothetical protein NP_753533.1 1466093 D 199310 CDS NP_753534.2 161486245 1035395 1466844..1467290 1 NC_004431.1 Escherichia coli K-12 ortholog: b1181; Escherichia coli O157:H7 ortholog: z1943; hypothetical protein 1467290 ycgN 1035395 ycgN Escherichia coli CFT073 hypothetical protein NP_753534.2 1466844 D 199310 CDS NP_753535.1 26247495 1035399 complement(1467497..1467778) 1 NC_004431.1 Residues 1 to 93 of 93 are 92.47 pct identical to residues 213 to 305 of 305 from MG1655 : b1182; hypothetical protein 1467778 1035399 c1630 Escherichia coli CFT073 hypothetical protein NP_753535.1 1467497 R 199310 CDS NP_753536.1 26247496 1035400 1468083..1468502 1 NC_004431.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1468502 umuD 1035400 umuD Escherichia coli CFT073 DNA polymerase V subunit UmuD NP_753536.1 1468083 D 199310 CDS NP_753537.1 26247497 1035402 1468502..1469770 1 NC_004431.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1469770 umuC 1035402 umuC Escherichia coli CFT073 DNA polymerase V subunit UmuC NP_753537.1 1468502 D 199310 CDS NP_753538.2 161486244 1035403 complement(1469815..1470345) 1 NC_004431.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1470345 dsbB 1035403 dsbB Escherichia coli CFT073 disulfide bond formation protein B NP_753538.2 1469815 R 199310 CDS NP_753539.2 161486243 1035404 complement(1470491..1472032) 1 NC_004431.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1472032 nhaB 1035404 nhaB Escherichia coli CFT073 sodium/proton antiporter NP_753539.2 1470491 R 199310 CDS NP_753540.1 26247500 1035406 1472254..1472973 1 NC_004431.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1472973 fadR 1035406 fadR Escherichia coli CFT073 fatty acid metabolism regulator NP_753540.1 1472254 D 199310 CDS NP_753541.1 26247501 1035407 complement(1472961..1473086) 1 NC_004431.1 hypothetical protein 1473086 1035407 c1636 Escherichia coli CFT073 hypothetical protein NP_753541.1 1472961 R 199310 CDS NP_753542.1 26247502 1035408 complement(1473136..1474668) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1188; Escherichia coli O157:H7 ortholog: z1951; SpoVR family protein 1474668 ycgB 1035408 ycgB Escherichia coli CFT073 SpoVR family protein NP_753542.1 1473136 R 199310 CDS NP_753543.2 161486242 1035409 1474998..1476296 1 NC_004431.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1476296 dadA 1035409 dadA Escherichia coli CFT073 D-amino acid dehydrogenase small subunit NP_753543.2 1474998 D 199310 CDS NP_753544.1 26247504 1035411 1476306..1477376 1 NC_004431.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1477376 dadX 1035411 dadX Escherichia coli CFT073 alanine racemase NP_753544.1 1476306 D 199310 CDS NP_753545.1 26247505 1035412 complement(1477433..1479169) 1 NC_004431.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1479169 ycgO 1035412 ycgO Escherichia coli CFT073 potassium/proton antiporter NP_753545.1 1477433 R 199310 CDS NP_753546.1 26247506 1035414 complement(1479264..1480178) 1 NC_004431.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1480178 ldcA 1035414 ldcA Escherichia coli CFT073 L,D-carboxypeptidase A NP_753546.1 1479264 R 199310 CDS YP_004853810.1 347357931 1035416 1480151..1480339 1 NC_004431.1 hypothetical protein 1480339 1035416 c1642 Escherichia coli CFT073 hypothetical protein YP_004853810.1 1480151 D 199310 CDS NP_753548.1 26247508 1035418 1480164..1480889 1 NC_004431.1 Escherichia coli K-12 ortholog: b1193; Escherichia coli O157:H7 ortholog: z1956; membrane-bound lytic murein transglycosylase E 1480889 mltE 1035418 mltE Escherichia coli CFT073 membrane-bound lytic murein transglycosylase E NP_753548.1 1480164 D 199310 CDS NP_753549.1 26247509 1035419 complement(1480891..1481625) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1194; Escherichia coli O157:H7 ortholog: z1959; hypothetical protein 1481625 ycgR 1035419 ycgR Escherichia coli CFT073 hypothetical protein NP_753549.1 1480891 R 199310 CDS NP_753550.1 26247510 1035421 1481793..1482080 1 NC_004431.1 Escherichia coli K-12 ortholog: b1195; Escherichia coli O157:H7 ortholog: z1960; transglycosylase associated protein 1482080 ymgE 1035421 ymgE Escherichia coli CFT073 transglycosylase associated protein NP_753550.1 1481793 D 199310 CDS NP_753551.1 26247511 1035422 complement(1482130..1484121) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1961; outer membrane receptor 1484121 prrA 1035422 prrA Escherichia coli CFT073 outer membrane receptor NP_753551.1 1482130 R 199310 CDS NP_753552.1 26247512 1035423 complement(1484126..1484980) 1 NC_004431.1 involved in molybdenum transport; molybdenum transport protein ModD 1484980 modD 1035423 modD Escherichia coli CFT073 molybdenum transport protein ModD NP_753552.1 1484126 R 199310 CDS NP_753553.1 26247513 1035424 complement(1484977..1485684) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1963; hypothetical protein 1485684 1035424 c1648 Escherichia coli CFT073 hypothetical protein NP_753553.1 1484977 R 199310 CDS NP_753554.1 26247514 1035425 1485730..1485879 1 NC_004431.1 hypothetical protein 1485879 1035425 c1649 Escherichia coli CFT073 hypothetical protein NP_753554.1 1485730 D 199310 CDS NP_753555.1 26247515 1035426 complement(1485799..1486557) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1964; iron compound ABC transporter, ATP-binding protein 1486557 1035426 c1650 Escherichia coli CFT073 iron compound ABC transporter, ATP-binding protein NP_753555.1 1485799 R 199310 CDS NP_753556.1 26247516 1035427 complement(1486554..1487450) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4288; Escherichia coli O157:H7 ortholog: z1965; iron ABC transporter permease 1487450 fecD 1035427 fecD Escherichia coli CFT073 iron ABC transporter permease NP_753556.1 1486554 R 199310 CDS NP_753557.1 26247517 1035429 complement(1487534..1488556) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1966; hypothetical protein 1488556 1035429 c1652 Escherichia coli CFT073 hypothetical protein NP_753557.1 1487534 R 199310 CDS NP_753558.1 26247518 1035430 complement(1488624..1488749) 1 NC_004431.1 hypothetical protein 1488749 1035430 c1653 Escherichia coli CFT073 hypothetical protein NP_753558.1 1488624 R 199310 CDS NP_753559.1 26247519 1035431 complement(1488887..1490584) 1 NC_004431.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1490584 treA 1035431 treA Escherichia coli CFT073 trehalase NP_753559.1 1488887 R 199310 CDS NP_753560.1 26247520 1035432 1490529..1490744 1 NC_004431.1 hypothetical protein 1490744 1035432 c1655 Escherichia coli CFT073 hypothetical protein NP_753560.1 1490529 D 199310 CDS NP_753561.1 26247521 1035433 complement(1490903..1492327) 1 NC_004431.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M 1492327 ycgC 1035433 ycgC Escherichia coli CFT073 dihydroxyacetone kinase subunit M NP_753561.1 1490903 R 199310 CDS NP_753562.1 26247522 1035434 complement(1492332..1493042) 1 NC_004431.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1493042 1035434 c1657 Escherichia coli CFT073 dihydroxyacetone kinase subunit DhaL NP_753562.1 1492332 R 199310 CDS NP_753563.1 26247523 1035435 complement(1492975..1494075) 1 NC_004431.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1494075 ycgT 1035435 ycgT Escherichia coli CFT073 dihydroxyacetone kinase subunit DhaK NP_753563.1 1492975 R 199310 CDS NP_753564.1 26247524 1035436 1494264..1496192 1 NC_004431.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1496192 1035436 c1659 Escherichia coli CFT073 DNA-binding transcriptional regulator DhaR NP_753564.1 1494264 D 199310 CDS NP_753565.1 26247525 1035437 complement(1496229..1496459) 1 NC_004431.1 hypothetical protein 1496459 1035437 c1660 Escherichia coli CFT073 hypothetical protein NP_753565.1 1496229 R 199310 CDS NP_753566.1 26247526 1035439 complement(1496597..1497688) 1 NC_004431.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1497688 ychF 1035439 ychF Escherichia coli CFT073 GTP-dependent nucleic acid-binding protein EngD NP_753566.1 1496597 R 199310 CDS NP_753567.1 26247527 1035440 complement(1497805..1498389) 1 NC_004431.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1498389 pth 1035440 pth Escherichia coli CFT073 peptidyl-tRNA hydrolase NP_753567.1 1497805 R 199310 CDS NP_753568.1 26247528 1035441 1498667..1498945 1 NC_004431.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1498945 ychH 1035441 ychH Escherichia coli CFT073 hypothetical protein NP_753568.1 1498667 D 199310 CDS NP_753569.1 26247529 1035442 complement(1499000..1500679) 1 NC_004431.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1500679 ychM 1035442 ychM Escherichia coli CFT073 sulfate transporter YchM NP_753569.1 1499000 R 199310 CDS NP_753570.1 26247530 1035443 complement(1500804..1501817) 1 NC_004431.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1501817 prsA 1035443 prsA Escherichia coli CFT073 ribose-phosphate pyrophosphokinase NP_753570.1 1500804 R 199310 CDS NP_753571.1 26247531 1035444 complement(1501902..1502753) 1 NC_004431.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1502753 ipk 1035444 ipk Escherichia coli CFT073 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_753571.1 1501902 R 199310 CDS NP_753572.1 26247532 1035445 complement(1502753..1503442) 1 NC_004431.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 1503442 lolB 1035445 lolB Escherichia coli CFT073 molecular chaperone LolB NP_753572.1 1502753 R 199310 CDS NP_753573.2 161486241 1035446 1503590..1504846 1 NC_004431.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1504846 hemA 1035446 hemA Escherichia coli CFT073 glutamyl-tRNA reductase NP_753573.2 1503590 D 199310 CDS NP_753574.1 26247534 1035447 1504888..1505970 1 NC_004431.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1505970 prfA 1035447 prfA Escherichia coli CFT073 peptide chain release factor 1 NP_753574.1 1504888 D 199310 CDS NP_753575.1 26247535 1035448 1505970..1506803 1 NC_004431.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1506803 hemK 1035448 hemK Escherichia coli CFT073 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase NP_753575.1 1505970 D 199310 CDS NP_753576.1 26247536 1035449 1506800..1507192 1 NC_004431.1 Escherichia coli K-12 ortholog: b1213; Escherichia coli O157:H7 ortholog: z1984; transcriptional regulator 1507192 1035449 c1671 Escherichia coli CFT073 transcriptional regulator NP_753576.1 1506800 D 199310 CDS NP_753577.1 26247537 1035450 1507196..1508005 1 NC_004431.1 Escherichia coli K-12 ortholog: b1214; Escherichia coli O157:H7 ortholog: z1985; transcriptional regulator 1508005 ychA 1035450 ychA Escherichia coli CFT073 transcriptional regulator NP_753577.1 1507196 D 199310 CDS NP_753578.1 26247538 1035451 complement(1508002..1508964) 1 NC_004431.1 hypothetical protein 1508964 1035451 c1673 Escherichia coli CFT073 hypothetical protein NP_753578.1 1508002 R 199310 CDS NP_753579.1 26247539 1035452 1508041..1508895 1 NC_004431.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1508895 kdsA 1035452 kdsA Escherichia coli CFT073 2-dehydro-3-deoxyphosphooctonate aldolase NP_753579.1 1508041 D 199310 CDS NP_753580.1 26247540 1035453 complement(1509044..1509322) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4955; hypothetical protein 1509322 1035453 c1675 Escherichia coli CFT073 hypothetical protein NP_753580.1 1509044 R 199310 CDS NP_753581.1 26247541 1035454 complement(1509561..1510748) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1216; Escherichia coli O157:H7 ortholog: z1991; calcium/sodium:proton antiporter 1510748 chaA 1035454 chaA Escherichia coli CFT073 calcium/sodium:proton antiporter NP_753581.1 1509561 R 199310 CDS NP_753582.1 26247542 1035455 1510931..1511161 1 NC_004431.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1511161 chaB 1035455 chaB Escherichia coli CFT073 cation transport regulator NP_753582.1 1510931 D 199310 CDS NP_753583.1 26247543 1035457 1511271..1512002 1 NC_004431.1 Escherichia coli K-12 ortholog: b1218; Escherichia coli O157:H7 ortholog: z1993; cation transport protein chaC 1512002 chaC 1035457 chaC Escherichia coli CFT073 cation transport protein chaC NP_753583.1 1511271 D 199310 CDS NP_753584.1 26247544 1035458 complement(1512046..1512399) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1219; Escherichia coli O157:H7 ortholog: z1994; hypothetical protein 1512399 ychN 1035458 ychN Escherichia coli CFT073 hypothetical protein NP_753584.1 1512046 R 199310 CDS NP_753585.1 26247545 1035459 1512584..1513978 1 NC_004431.1 Escherichia coli K-12 ortholog: b1220; Escherichia coli O157:H7 ortholog: z1995; hypothetical protein 1513978 ychP 1035459 ychP Escherichia coli CFT073 hypothetical protein NP_753585.1 1512584 D 199310 CDS NP_753586.1 26247546 1035460 complement(1513979..1514695) 1 NC_004431.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1514695 narL 1035460 narL Escherichia coli CFT073 transcriptional regulator NarL NP_753586.1 1513979 R 199310 CDS NP_753587.1 26247547 1035461 complement(1514622..1516418) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1222; Escherichia coli O157:H7 ortholog: z1998; nitrate/nitrite sensor protein NarX 1516418 narX 1035461 narX Escherichia coli CFT073 nitrate/nitrite sensor protein NarX NP_753587.1 1514622 R 199310 CDS NP_753588.1 26247548 1035462 1516444..1516662 1 NC_004431.1 hypothetical protein 1516662 1035462 c1683 Escherichia coli CFT073 hypothetical protein NP_753588.1 1516444 D 199310 CDS NP_753589.1 26247549 1035463 1516751..1518148 1 NC_004431.1 Nitrite facilitator 1; Escherichia coli K-12 ortholog: b1223; Escherichia coli O157:H7 ortholog: z2000; nitrite extrusion protein 1 1518148 narK 1035463 narK Escherichia coli CFT073 nitrite extrusion protein 1 NP_753589.1 1516751 D 199310 CDS NP_753590.1 26247550 1035464 1518541..1522284 1 NC_004431.1 Escherichia coli K-12 ortholog: b1224; Escherichia coli O157:H7 ortholog: z2001; respiratory nitrate reductase 1 subunit alpha 1522284 narG 1035464 narG Escherichia coli CFT073 respiratory nitrate reductase 1 subunit alpha NP_753590.1 1518541 D 199310 CDS NP_753591.1 26247551 1035465 1522281..1523819 1 NC_004431.1 Escherichia coli K-12 ortholog: b1225; Escherichia coli O157:H7 ortholog: z2002; respiratory nitrate reductase 1 subunit beta 1523819 narH 1035465 narH Escherichia coli CFT073 respiratory nitrate reductase 1 subunit beta NP_753591.1 1522281 D 199310 CDS NP_753592.1 26247552 1035466 1523816..1524526 1 NC_004431.1 Escherichia coli K-12 ortholog: b1226; Escherichia coli O157:H7 ortholog: z2003; respiratory nitrate reductase 1 subunit delta 1524526 narJ 1035466 narJ Escherichia coli CFT073 respiratory nitrate reductase 1 subunit delta NP_753592.1 1523816 D 199310 CDS NP_753593.1 26247553 1035467 1524526..1525203 1 NC_004431.1 Escherichia coli K-12 ortholog: b1227; Escherichia coli O157:H7 ortholog: z2004; respiratory nitrate reductase 1 subunit gamma 1525203 narI 1035467 narI Escherichia coli CFT073 respiratory nitrate reductase 1 subunit gamma NP_753593.1 1524526 D 199310 CDS NP_753594.1 26247554 1035468 1525279..1526322 1 NC_004431.1 Residues 176 to 347 of 347 are 80.81 pct identical to residues 4 to 175 of 175 from GenPept.129 : >emb|CAA21325.1| (AL031866) ORF3, len: 175 aa,similar to C-terminal end of XCU70053_2 Xanthomonas campestris gumO (435 aa), possible frameshift, this ORF is the prolongation of ORF 4 also similar to XCU70053_2. Fasta score: opt: 367, E(): 1.8e-17 39.5%identity in 172 aa overlap [Yersinia pestis]; hypothetical protein 1526322 1035468 c1689 Escherichia coli CFT073 hypothetical protein NP_753594.1 1525279 D 199310 CDS NP_753595.1 26247555 1035469 1526319..1527335 1 NC_004431.1 Escherichia coli K-12 ortholog: b0868; Escherichia coli O157:H7 ortholog: z1102; hypothetical protein 1527335 1035469 c1690 Escherichia coli CFT073 hypothetical protein NP_753595.1 1526319 D 199310 CDS NP_753596.1 26247556 1035471 1527313..1528119 1 NC_004431.1 Residues 1 to 268 of 268 are 69.02 pct identical to residues 1 to 268 of 268 from GenPept.129 : >emb|CAC90793.1| (AJ414150) conserved hypothetical protein [Yersinia pestis]; gumP-like protein 1528119 1035471 c1691 Escherichia coli CFT073 gumP-like protein NP_753596.1 1527313 D 199310 CDS NP_753597.1 26247557 1035472 1528116..1529402 1 NC_004431.1 Residues 1 to 424 of 428 are 66.03 pct identical to residues 1 to 424 of 428 from GenPept.129 : >emb|CAC90794.1| (AJ414150) coenzyme synthetase [Yersinia pestis]; hypothetical protein 1529402 1035472 c1692 Escherichia coli CFT073 hypothetical protein NP_753597.1 1528116 D 199310 CDS NP_753598.1 26247558 1035473 1529387..1530001 1 NC_004431.1 Residues 24 to 188 of 204 are 27.52 pct identical to residues 23 to 198 of 219 from GenPept.129 : >gb|AAK79457.1|AE007659_12 (AE007659) Protein of phosphatidic acid phosphatase family, YNBD E.coli ortholog [Clostridium acetobutylicum]; hypothetical protein 1530001 1035473 c1693 Escherichia coli CFT073 hypothetical protein NP_753598.1 1529387 D 199310 CDS NP_753599.1 26247559 1035474 1529994..1531118 1 NC_004431.1 Residues 12 to 235 of 374 are 32.46 pct identical to residues 19 to 246 of 317 from GenPept.129 : >dbj|BAB48523.1| (AP002996) hypothetical protein [Mesorhizobium loti]; hypothetical protein 1531118 1035474 c1694 Escherichia coli CFT073 hypothetical protein NP_753599.1 1529994 D 199310 CDS NP_753600.1 26247560 1035475 1531105..1532196 1 NC_004431.1 Residues 23 to 359 of 363 are 24.20 pct identical to residues 19 to 357 of 359 from GenPept.129 : >dbj|BAA18502.1| (D90914) delta-6 desaturase [Synechocystis sp. PCC 6803]; hypothetical protein 1532196 1035475 c1695 Escherichia coli CFT073 hypothetical protein NP_753600.1 1531105 D 199310 CDS NP_753601.1 26247561 1035478 complement(1532753..1533595) 1 NC_004431.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1533595 purU 1035478 purU Escherichia coli CFT073 formyltetrahydrofolate deformylase NP_753601.1 1532753 R 199310 CDS NP_753602.2 161486240 1035479 complement(1533645..1534103) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1233; Escherichia coli O157:H7 ortholog: z2009; hypothetical protein 1534103 ychJ 1035479 ychJ Escherichia coli CFT073 hypothetical protein NP_753602.2 1533645 R 199310 CDS NP_753603.1 26247563 1035480 1534177..1535121 1 NC_004431.1 Escherichia coli K-12 ortholog: b1234; Escherichia coli O157:H7 ortholog: z2010; hypothetical protein 1535121 ychK 1035480 ychK Escherichia coli CFT073 hypothetical protein NP_753603.1 1534177 D 199310 CDS NP_753604.1 26247564 1035481 1535213..1536226 1 NC_004431.1 Escherichia coli K-12 ortholog: b1235; Escherichia coli O157:H7 ortholog: z2011; response regulator of RpoS 1536226 hnr 1035481 hnr Escherichia coli CFT073 response regulator of RpoS NP_753604.1 1535213 D 199310 CDS NP_753605.1 26247565 1035482 1536428..1537336 1 NC_004431.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1537336 galU 1035482 galU Escherichia coli CFT073 UTP-glucose-1-phosphate uridylyltransferase NP_753605.1 1536428 D 199310 CDS NP_753606.1 26247566 1035483 complement(1537480..1537893) 1 NC_004431.1 Histone-like protein HLP-II; Escherichia coli K-12 ortholog: b1237; Escherichia coli O157:H7 ortholog: z2013; global DNA-binding transcriptional dual regulator H-NS 1537893 hns 1035483 hns Escherichia coli CFT073 global DNA-binding transcriptional dual regulator H-NS NP_753606.1 1537480 R 199310 CDS NP_753607.1 26247567 1035484 complement(1537985..1538113) 1 NC_004431.1 hypothetical protein 1538113 1035484 c1702 Escherichia coli CFT073 hypothetical protein NP_753607.1 1537985 R 199310 CDS NP_753608.1 26247568 1035485 1538497..1539114 1 NC_004431.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1539114 tdk 1035485 tdk Escherichia coli CFT073 thymidine kinase NP_753608.1 1538497 D 199310 CDS NP_753609.1 26247569 1035486 complement(1539241..1540446) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4278; transposase insG 1540446 1035486 c1704 Escherichia coli CFT073 transposase insG NP_753609.1 1539241 R 199310 CDS NP_753610.1 26247570 1035487 complement(1540572..1543247) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1241; Escherichia coli O157:H7 ortholog: z2016; multifunctional; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1543247 adhE 1035487 adhE Escherichia coli CFT073 bifunctional acetaldehyde-CoA/alcohol dehydrogenase NP_753610.1 1540572 R 199310 CDS NP_753611.1 26247571 1035488 1543724..1544371 1 NC_004431.1 Escherichia coli K-12 ortholog: b1242; Escherichia coli O157:H7 ortholog: z2017; hypothetical protein 1544371 ychE 1035488 ychE Escherichia coli CFT073 hypothetical protein NP_753611.1 1543724 D 199310 CDS NP_753612.1 26247572 1035489 1545037..1546740 1 NC_004431.1 Escherichia coli K-12 ortholog: b1243; Escherichia coli O157:H7 ortholog: z2019; periplasmic oligopeptide-binding protein 1546740 oppA 1035489 oppA Escherichia coli CFT073 periplasmic oligopeptide-binding protein NP_753612.1 1545037 D 199310 CDS NP_753613.1 26247573 1035490 1546826..1547746 1 NC_004431.1 Escherichia coli K-12 ortholog: b1244; Escherichia coli O157:H7 ortholog: z2020; oligopeptide transporter permease 1547746 oppB 1035490 oppB Escherichia coli CFT073 oligopeptide transporter permease NP_753613.1 1546826 D 199310 CDS NP_753614.1 26247574 1035491 1547761..1548669 1 NC_004431.1 Escherichia coli K-12 ortholog: b1245; Escherichia coli O157:H7 ortholog: z2021; oligopeptide transport system permease oppC 1548669 oppC 1035491 oppC Escherichia coli CFT073 oligopeptide transport system permease oppC NP_753614.1 1547761 D 199310 CDS NP_753615.1 26247575 1035492 1548681..1549694 1 NC_004431.1 Escherichia coli K-12 ortholog: b1246; Escherichia coli O157:H7 ortholog: z2022; oligopeptide transporter ATP-binding component 1549694 oppD 1035492 oppD Escherichia coli CFT073 oligopeptide transporter ATP-binding component NP_753615.1 1548681 D 199310 CDS NP_753616.1 26247576 1035493 1549691..1550695 1 NC_004431.1 Escherichia coli K-12 ortholog: b1247; Escherichia coli O157:H7 ortholog: z2023; oligopeptide transport ATP-binding protein oppF 1550695 oppF 1035493 oppF Escherichia coli CFT073 oligopeptide transport ATP-binding protein oppF NP_753616.1 1549691 D 199310 CDS NP_753617.2 161486239 1035494 complement(1550748..1551077) 1 NC_004431.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1551077 yciU 1035494 yciU Escherichia coli CFT073 dsDNA-mimic protein NP_753617.2 1550748 R 199310 CDS NP_753618.1 26247578 1035495 complement(1551112..1552572) 1 NC_004431.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1552572 cls 1035495 cls Escherichia coli CFT073 cardiolipin synthetase NP_753618.1 1551112 R 199310 CDS NP_753619.1 26247579 1035496 1552604..1552888 1 NC_004431.1 hypothetical protein 1552888 1035496 c1714 Escherichia coli CFT073 hypothetical protein NP_753619.1 1552604 D 199310 CDS NP_753620.1 26247580 1035497 complement(1552943..1554214) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1250; Escherichia coli O157:H7 ortholog: z2028; voltage-gated potassium channel 1554214 kch 1035497 kch Escherichia coli CFT073 voltage-gated potassium channel NP_753620.1 1552943 R 199310 CDS NP_753621.2 161486238 1035498 complement(1554496..1554792) 1 NC_004431.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1554792 yciI 1035498 yciI Escherichia coli CFT073 hypothetical protein NP_753621.2 1554496 R 199310 CDS NP_753622.1 26247582 1035499 1554965..1555732 1 NC_004431.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1555732 tonB 1035499 tonB Escherichia coli CFT073 transport protein TonB NP_753622.1 1554965 D 199310 CDS NP_753623.1 26247583 1035500 complement(1555198..1555443) 1 NC_004431.1 hypothetical protein 1555443 1035500 c1718 Escherichia coli CFT073 hypothetical protein NP_753623.1 1555198 R 199310 CDS NP_753624.1 26247584 1035501 complement(1555772..1556170) 1 NC_004431.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1556170 yciA 1035501 yciA Escherichia coli CFT073 acyl-CoA thioester hydrolase NP_753624.1 1555772 R 199310 CDS NP_753625.1 26247585 1035502 complement(1556275..1556814) 1 NC_004431.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1556814 ispZ 1035502 ispZ Escherichia coli CFT073 intracellular septation protein A NP_753625.1 1556275 R 199310 CDS NP_753626.1 26247586 1035503 complement(1556844..1557587) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1255; Escherichia coli O157:H7 ortholog: z2033; hypothetical protein 1557587 yciC 1035503 yciC Escherichia coli CFT073 hypothetical protein NP_753626.1 1556844 R 199310 CDS NP_753627.1 26247587 1035505 1557866..1558582 1 NC_004431.1 receptor for colicin S4; outer membrane protein W 1558582 ompW 1035505 ompW Escherichia coli CFT073 outer membrane protein W NP_753627.1 1557866 D 199310 CDS NP_753628.1 26247588 1035506 complement(1558641..1559147) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1257; Escherichia coli O157:H7 ortholog: z2555; hypothetical protein 1559147 yciE 1035506 yciE Escherichia coli CFT073 hypothetical protein NP_753628.1 1558641 R 199310 CDS NP_753629.1 26247589 1035507 complement(1559193..1559696) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1258; Escherichia coli O157:H7 ortholog: z2554; hypothetical protein 1559696 yciF 1035507 yciF Escherichia coli CFT073 hypothetical protein NP_753629.1 1559193 R 199310 CDS NP_753630.1 26247590 1035508 complement(1560020..1560826) 1 NC_004431.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1560826 trpA 1035508 trpA Escherichia coli CFT073 tryptophan synthase subunit alpha NP_753630.1 1560020 R 199310 CDS NP_753631.1 26247591 1035509 complement(1560826..1562019) 1 NC_004431.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1562019 trpB 1035509 trpB Escherichia coli CFT073 tryptophan synthase subunit beta NP_753631.1 1560826 R 199310 CDS NP_753632.1 26247592 1035512 complement(1563393..1564988) 1 NC_004431.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1564988 trpD 1035512 trpD Escherichia coli CFT073 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase NP_753632.1 1563393 R 199310 CDS NP_753633.1 26247593 1035513 complement(1564988..1566550) 1 NC_004431.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1566550 trpE 1035513 trpE Escherichia coli CFT073 anthranilate synthase component I NP_753633.1 1564988 R 199310 CDS NP_753635.1 26247595 1035515 1566824..1567705 1 NC_004431.1 Escherichia coli K-12 ortholog: b1266; Escherichia coli O157:H7 ortholog: z2544; protein trpH 1567705 trpH 1035515 trpH Escherichia coli CFT073 protein trpH NP_753635.1 1566824 D 199310 CDS NP_753636.1 26247596 1035516 1567666..1568322 1 NC_004431.1 Escherichia coli K-12 ortholog: b1267; Escherichia coli O157:H7 ortholog: z2543; hypothetical protein 1568322 yciO 1035516 yciO Escherichia coli CFT073 hypothetical protein NP_753636.1 1567666 D 199310 CDS NP_753637.1 26247597 1035517 1568347..1570239 1 NC_004431.1 Escherichia coli K-12 ortholog: b1268; hypothetical protein 1570239 yciQ 1035517 yciQ Escherichia coli CFT073 hypothetical protein NP_753637.1 1568347 D 199310 CDS NP_753638.1 26247598 1035518 1570452..1571327 1 NC_004431.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1571327 yciL 1035518 yciL Escherichia coli CFT073 23S rRNA pseudouridylate synthase B NP_753638.1 1570452 D 199310 CDS NP_753639.1 26247599 1035519 complement(1571367..1571957) 1 NC_004431.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1571957 btuR 1035519 btuR Escherichia coli CFT073 cob(I)yrinic acid a,c-diamide adenosyltransferase NP_753639.1 1571367 R 199310 CDS NP_753640.1 26247600 1035520 complement(1571954..1572712) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1271; Escherichia coli O157:H7 ortholog: z2539; short chain dehydrogenase 1572712 yciK 1035520 yciK Escherichia coli CFT073 short chain dehydrogenase NP_753640.1 1571954 R 199310 CDS NP_753641.1 26247601 1035521 1572932..1573981 1 NC_004431.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1573981 sohB 1035521 sohB Escherichia coli CFT073 periplasmic protease NP_753641.1 1572932 D 199310 CDS NP_753642.1 26247602 1035522 1574161..1574619 1 NC_004431.1 Residues 1 to 152 of 152 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1574619 1035522 c1738 Escherichia coli CFT073 hypothetical protein NP_753642.1 1574161 D 199310 CDS NP_753643.1 26247603 1035523 complement(1574728..1574979) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1273; Escherichia coli O157:H7 ortholog: z2537; hypothetical protein 1574979 yciN 1035523 yciN Escherichia coli CFT073 hypothetical protein NP_753643.1 1574728 R 199310 CDS NP_753644.1 26247604 1035524 1574972..1575127 1 NC_004431.1 hypothetical protein 1575127 1035524 c1740 Escherichia coli CFT073 hypothetical protein NP_753644.1 1574972 D 199310 CDS NP_753645.1 26247605 1035525 1575317..1577956 1 NC_004431.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1577956 topA 1035525 topA Escherichia coli CFT073 DNA topoisomerase I NP_753645.1 1575317 D 199310 CDS NP_753646.1 26247606 1035526 1578166..1579140 1 NC_004431.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1579140 cysB 1035526 cysB Escherichia coli CFT073 transcriptional regulator CysB NP_753646.1 1578166 D 199310 CDS NP_753647.1 26247607 1035527 1579435..1579599 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2534; hypothetical protein 1579599 1035527 c1743 Escherichia coli CFT073 hypothetical protein NP_753647.1 1579435 D 199310 CDS NP_753648.1 26247608 1035528 1579581..1579769 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2533; hypothetical protein 1579769 1035528 c1744 Escherichia coli CFT073 hypothetical protein NP_753648.1 1579581 D 199310 CDS NP_753649.1 26247609 1035529 1580128..1582803 1 NC_004431.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1582803 acnA 1035529 acnA Escherichia coli CFT073 aconitate hydratase NP_753649.1 1580128 D 199310 CDS NP_753650.2 161486237 1035530 complement(1582867..1583457) 1 NC_004431.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1583457 ribA 1035530 ribA Escherichia coli CFT073 GTP cyclohydrolase II NP_753650.2 1582867 R 199310 CDS NP_753651.1 26247611 1035531 1583627..1584391 1 NC_004431.1 Escherichia coli K-12 ortholog: b1278; Escherichia coli O157:H7 ortholog: z2529; phosphatidylglycerophosphatase B 1584391 pgpB 1035531 pgpB Escherichia coli CFT073 phosphatidylglycerophosphatase B NP_753651.1 1583627 D 199310 CDS NP_753652.1 26247612 1035532 1584540..1584848 1 NC_004431.1 Escherichia coli K-12 ortholog: b1279; Escherichia coli O157:H7 ortholog: z2528; hypothetical protein 1584848 yciS 1035532 yciS Escherichia coli CFT073 hypothetical protein NP_753652.1 1584540 D 199310 CDS NP_753653.1 26247613 1035533 1584855..1586024 1 NC_004431.1 Escherichia coli K-12 ortholog: b1280; Escherichia coli O157:H7 ortholog: z2526; tetratricopeptide repeat protein 1586024 yciM 1035533 yciM Escherichia coli CFT073 tetratricopeptide repeat protein NP_753653.1 1584855 D 199310 CDS NP_753654.1 26247614 1035534 1586064..1586951 1 NC_004431.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1586951 pyrF 1035534 pyrF Escherichia coli CFT073 orotidine 5'-phosphate decarboxylase NP_753654.1 1586064 D 199310 CDS NP_753655.1 26247615 1035535 1586948..1587277 1 NC_004431.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1587277 yciH 1035535 yciH Escherichia coli CFT073 translation initiation factor Sui1 NP_753655.1 1586948 D 199310 CDS NP_753656.1 26247616 1035536 1587301..1587453 1 NC_004431.1 hypothetical protein 1587453 1035536 c1752 Escherichia coli CFT073 hypothetical protein NP_753656.1 1587301 D 199310 CDS NP_753657.1 26247617 1035537 complement(1587403..1587621) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1283; Escherichia coli O157:H7 ortholog: z2523; lipoprotein 1587621 osmB 1035537 osmB Escherichia coli CFT073 lipoprotein NP_753657.1 1587403 R 199310 CDS NP_753658.1 26247618 1035538 complement(1587890..1588639) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1284; Escherichia coli O157:H7 ortholog: z2521; transcriptional regulator YciT 1588639 yciT 1035538 yciT Escherichia coli CFT073 transcriptional regulator YciT NP_753658.1 1587890 R 199310 CDS NP_753659.1 26247619 1035539 complement(1588728..1588901) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2519; hypothetical protein 1588901 1035539 c1755 Escherichia coli CFT073 hypothetical protein NP_753659.1 1588728 R 199310 CDS NP_753660.1 26247620 1035540 complement(1589049..1591034) 1 NC_004431.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1591034 yciR 1035540 yciR Escherichia coli CFT073 RNase II stability modulator NP_753660.1 1589049 R 199310 CDS NP_753661.1 26247621 1035542 complement(1591268..1593202) 1 NC_004431.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1593202 rnb 1035542 rnb Escherichia coli CFT073 exoribonuclease II NP_753661.1 1591268 R 199310 CDS NP_753662.3 347357896 1035543 complement(1593270..1594475) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1287; Escherichia coli O157:H7 ortholog: z2513; hypothetical protein 1594475 yciW 1035543 yciW Escherichia coli CFT073 hypothetical protein NP_753662.3 1593270 R 199310 CDS NP_753663.1 26247623 1035544 complement(1594542..1595330) 1 NC_004431.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1595330 fabI 1035544 fabI Escherichia coli CFT073 enoyl-ACP reductase NP_753663.1 1594542 R 199310 CDS NP_753664.1 26247624 1035546 1595709..1596374 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2510; transcriptional repressor 1596374 1035546 c1760 Escherichia coli CFT073 transcriptional repressor NP_753664.1 1595709 D 199310 CDS NP_753665.1 26247625 1035547 1596490..1597644 1 NC_004431.1 Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z2509; acriflavin resistance protein A 1597644 1035547 c1761 Escherichia coli CFT073 acriflavin resistance protein A NP_753665.1 1596490 D 199310 CDS NP_753666.1 26247626 1035548 1597613..1597756 1 NC_004431.1 hypothetical protein 1597756 1035548 c1762 Escherichia coli CFT073 hypothetical protein NP_753666.1 1597613 D 199310 CDS NP_753667.1 26247627 1035549 complement(1597620..1597748) 1 NC_004431.1 hypothetical protein 1597748 1035549 c1763 Escherichia coli CFT073 hypothetical protein NP_753667.1 1597620 R 199310 CDS NP_753668.1 26247628 1035550 1597734..1600751 1 NC_004431.1 Escherichia coli K-12 ortholog: b0462; Escherichia coli O157:H7 ortholog: z2508; acriflavin resistance protein B 1600751 1035550 c1764 Escherichia coli CFT073 acriflavin resistance protein B NP_753668.1 1597734 D 199310 CDS NP_753669.1 26247629 1035551 1600755..1602128 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2506; hypothetical protein 1602128 1035551 c1765 Escherichia coli CFT073 hypothetical protein NP_753669.1 1600755 D 199310 CDS NP_753670.1 26247630 1035552 1602137..1603300 1 NC_004431.1 Residues 1 to 387 of 387 are 98.96 pct identical to residues 1 to 387 of 387 from GenPept.129 : >dbj|BAB35289.1| (AP002556) membrane transport protein [Escherichia coli O157:H7]; membrane transporter 1603300 1035552 c1766 Escherichia coli CFT073 membrane transporter NP_753670.1 1602137 D 199310 CDS NP_753671.1 26247631 1035553 complement(1603348..1604154) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1290; Escherichia coli O157:H7 ortholog: z2500; peptide transport system ATP-binding protein sapF 1604154 sapF 1035553 sapF Escherichia coli CFT073 peptide transport system ATP-binding protein sapF NP_753671.1 1603348 R 199310 CDS NP_753672.1 26247632 1035554 complement(1604156..1605148) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1291; Escherichia coli O157:H7 ortholog: z2499; peptide transport system ATP-binding protein sapD 1605148 sapD 1035554 sapD Escherichia coli CFT073 peptide transport system ATP-binding protein sapD NP_753672.1 1604156 R 199310 CDS NP_753673.1 26247633 1035555 complement(1605148..1606038) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1292; Escherichia coli O157:H7 ortholog: z2498; peptide transport system permease sapC 1606038 sapC 1035555 sapC Escherichia coli CFT073 peptide transport system permease sapC NP_753673.1 1605148 R 199310 CDS NP_753674.1 26247634 1035556 complement(1606025..1606990) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1293; Escherichia coli O157:H7 ortholog: z2496; peptide transport system permease sapB 1606990 sapB 1035556 sapB Escherichia coli CFT073 peptide transport system permease sapB NP_753674.1 1606025 R 199310 CDS NP_753675.1 26247635 1035557 complement(1606987..1608630) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1294; Escherichia coli O157:H7 ortholog: z2494; peptide transport periplasmic protein sapA 1608630 sapA 1035557 sapA Escherichia coli CFT073 peptide transport periplasmic protein sapA NP_753675.1 1606987 R 199310 CDS NP_753676.1 26247636 1035558 complement(1608943..1609188) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1295; Escherichia coli O157:H7 ortholog: z2493; hypothetical protein 1609188 ymjA 1035558 ymjA Escherichia coli CFT073 hypothetical protein NP_753676.1 1608943 R 199310 CDS NP_753677.3 347357895 1035559 complement(1609615..1610607) 1 NC_004431.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1610607 pspF 1035559 pspF Escherichia coli CFT073 phage shock protein operon transcriptional activator NP_753677.3 1609615 R 199310 CDS NP_753678.1 26247638 1035560 1610758..1611426 1 NC_004431.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1611426 pspA 1035560 pspA Escherichia coli CFT073 phage shock protein PspA NP_753678.1 1610758 D 199310 CDS NP_753679.1 26247639 1035561 1611480..1611704 1 NC_004431.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1611704 pspB 1035561 pspB Escherichia coli CFT073 phage shock protein B NP_753679.1 1611480 D 199310 CDS NP_753680.1 26247640 1035562 complement(1611499..1611756) 1 NC_004431.1 hypothetical protein 1611756 1035562 c1776 Escherichia coli CFT073 hypothetical protein NP_753680.1 1611499 R 199310 CDS NP_753681.1 26247641 1035563 1611704..1612063 1 NC_004431.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1612063 pspC 1035563 pspC Escherichia coli CFT073 DNA-binding transcriptional activator PspC NP_753681.1 1611704 D 199310 CDS NP_753682.1 26247642 1035564 1612072..1612293 1 NC_004431.1 Escherichia coli K-12 ortholog: b1307; Escherichia coli O157:H7 ortholog: z2478; peripheral inner membrane phage-shock protein 1612293 pspD 1035564 pspD Escherichia coli CFT073 peripheral inner membrane phage-shock protein NP_753682.1 1612072 D 199310 CDS NP_753683.1 26247643 1035565 1612368..1612682 1 NC_004431.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1612682 pspE 1035565 pspE Escherichia coli CFT073 thiosulfate:cyanide sulfurtransferase NP_753683.1 1612368 D 199310 CDS NP_753684.1 26247644 1035566 1612869..1614575 1 NC_004431.1 Escherichia coli K-12 ortholog: b1309; Escherichia coli O157:H7 ortholog: z2475; sucrose phosphorylase 1614575 ycjM 1035566 ycjM Escherichia coli CFT073 sucrose phosphorylase NP_753684.1 1612869 D 199310 CDS NP_753685.1 26247645 1035567 complement(1614390..1614590) 1 NC_004431.1 hypothetical protein 1614590 1035567 c1781 Escherichia coli CFT073 hypothetical protein NP_753685.1 1614390 R 199310 CDS NP_753686.1 26247646 1035568 1614589..1615881 1 NC_004431.1 Escherichia coli K-12 ortholog: b1310; ABC transporter periplasmic-binding protein 1615881 ycjN 1035568 ycjN Escherichia coli CFT073 ABC transporter periplasmic-binding protein NP_753686.1 1614589 D 199310 CDS NP_753687.1 26247647 1035569 1615902..1616783 1 NC_004431.1 Escherichia coli K-12 ortholog: b1311; Escherichia coli O157:H7 ortholog: z2472; ABC transporter permease 1616783 ycjO 1035569 ycjO Escherichia coli CFT073 ABC transporter permease NP_753687.1 1615902 D 199310 CDS NP_753688.1 26247648 1035570 1616770..1617612 1 NC_004431.1 Escherichia coli K-12 ortholog: b1312; Escherichia coli O157:H7 ortholog: z2471; ABC transporter permease 1617612 ycjP 1035570 ycjP Escherichia coli CFT073 ABC transporter permease NP_753688.1 1616770 D 199310 CDS NP_753689.1 26247649 1035571 1617643..1618695 1 NC_004431.1 Escherichia coli K-12 ortholog: b1313; Escherichia coli O157:H7 ortholog: z2470; hypothetical protein 1618695 ycjQ 1035571 ycjQ Escherichia coli CFT073 hypothetical protein NP_753689.1 1617643 D 199310 CDS NP_753690.1 26247650 1035572 1618705..1619502 1 NC_004431.1 Escherichia coli K-12 ortholog: b1314; Escherichia coli O157:H7 ortholog: z2469; hypothetical protein 1619502 ycjR 1035572 ycjR Escherichia coli CFT073 hypothetical protein NP_753690.1 1618705 D 199310 CDS NP_753691.1 26247651 1035573 1619512..1620567 1 NC_004431.1 Escherichia coli K-12 ortholog: b1315; Escherichia coli O157:H7 ortholog: z2468; oxidoreductase ycjS 1620567 ycjS 1035573 ycjS Escherichia coli CFT073 oxidoreductase ycjS NP_753691.1 1619512 D 199310 CDS NP_753692.1 26247652 1035574 1620564..1622831 1 NC_004431.1 Escherichia coli K-12 ortholog: b1316; Escherichia coli O157:H7 ortholog: z2467; transport protein YcjT 1622831 ycjT 1035574 ycjT Escherichia coli CFT073 transport protein YcjT NP_753692.1 1620564 D 199310 CDS NP_753693.1 26247653 1035575 1622828..1623487 1 NC_004431.1 Escherichia coli K-12 ortholog: b1317; Escherichia coli O157:H7 ortholog: z2465; beta-phosphoglucomutase 1623487 ycjU 1035575 ycjU Escherichia coli CFT073 beta-phosphoglucomutase NP_753693.1 1622828 D 199310 CDS NP_753694.1 26247654 1035576 1623501..1624583 1 NC_004431.1 Escherichia coli K-12 ortholog: b1318; Escherichia coli O157:H7 ortholog: z2463; ABC transporter ATP-binding protein 1624583 ycjV 1035576 ycjV Escherichia coli CFT073 ABC transporter ATP-binding protein NP_753694.1 1623501 D 199310 CDS NP_753695.1 26247655 1035577 1624577..1625533 1 NC_004431.1 Escherichia coli K-12 ortholog: b1319; Escherichia coli O157:H7 ortholog: z2462; outer membrane protein G 1625533 ompG 1035577 ompG Escherichia coli CFT073 outer membrane protein G NP_753695.1 1624577 D 199310 CDS NP_753696.1 26247656 1035578 complement(1625584..1626582) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1320; Escherichia coli O157:H7 ortholog: z2461; transcriptional regulator YcjW 1626582 ycjW 1035578 ycjW Escherichia coli CFT073 transcriptional regulator YcjW NP_753696.1 1625584 R 199310 CDS NP_753697.1 26247657 1035579 1626666..1628135 1 NC_004431.1 Escherichia coli K-12 ortholog: b1321; Escherichia coli O157:H7 ortholog: z2458; hypothetical protein 1628135 ycjX 1035579 ycjX Escherichia coli CFT073 hypothetical protein NP_753697.1 1626666 D 199310 CDS NP_753698.1 26247658 1035580 1628132..1629193 1 NC_004431.1 Escherichia coli K-12 ortholog: b1322; Escherichia coli O157:H7 ortholog: z2456; hypothetical protein 1629193 ycjF 1035580 ycjF Escherichia coli CFT073 hypothetical protein NP_753698.1 1628132 D 199310 CDS NP_753699.1 26247659 1035581 1629314..1630882 1 NC_004431.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1630882 tyrR 1035581 tyrR Escherichia coli CFT073 DNA-binding transcriptional regulator TyrR NP_753699.1 1629314 D 199310 CDS NP_753700.1 26247660 1035582 complement(1630926..1631432) 1 NC_004431.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1631432 tpx 1035582 tpx Escherichia coli CFT073 thiol peroxidase NP_753700.1 1630926 R 199310 CDS NP_753701.1 26247661 1035583 1631509..1632516 1 NC_004431.1 Escherichia coli K-12 ortholog: b1325; Escherichia coli O157:H7 ortholog: z2450; hypothetical protein 1632516 ycjG 1035583 ycjG Escherichia coli CFT073 hypothetical protein NP_753701.1 1631509 D 199310 CDS NP_753702.1 26247662 1035586 complement(1633510..1634148) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2446; hypothetical protein 1634148 1035586 c1800 Escherichia coli CFT073 hypothetical protein NP_753702.1 1633510 R 199310 CDS NP_753703.1 26247663 1035588 complement(1634219..1635151) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1327; Escherichia coli O157:H7 ortholog: z2442; hypothetical protein 1635151 1035588 c1801 Escherichia coli CFT073 hypothetical protein NP_753703.1 1634219 R 199310 CDS NP_753704.1 26247664 1035589 1635277..1636176 1 NC_004431.1 Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 1636176 1035589 c1802 Escherichia coli CFT073 transcriptional regulator YcjZ NP_753704.1 1635277 D 199310 CDS NP_753705.1 26247665 1035590 1636492..1638126 1 NC_004431.1 Escherichia coli K-12 ortholog: b1329; Escherichia coli O157:H7 ortholog: z2438; periplasmic murein peptide-binding protein 1638126 mppA 1035590 mppA Escherichia coli CFT073 periplasmic murein peptide-binding protein NP_753705.1 1636492 D 199310 CDS NP_753706.1 26247666 1035591 complement(1638177..1639208) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1330; Escherichia coli O157:H7 ortholog: z2437; hypothetical protein 1639208 ynaI 1035591 ynaI Escherichia coli CFT073 hypothetical protein NP_753706.1 1638177 R 199310 CDS NP_753707.1 26247667 1035592 1639452..1639709 1 NC_004431.1 Escherichia coli K-12 ortholog: b1332; Escherichia coli O157:H7 ortholog: z2436; hypothetical protein 1639709 ynaJ 1035592 ynaJ Escherichia coli CFT073 hypothetical protein NP_753707.1 1639452 D 199310 CDS NP_753708.1 26247668 1035593 complement(1639759..1640709) 1 NC_004431.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1640709 ydaA 1035593 ydaA Escherichia coli CFT073 universal stress protein UspE NP_753708.1 1639759 R 199310 CDS NP_753709.2 161486234 1035594 complement(1640861..1641613) 1 NC_004431.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1641613 fnr 1035594 fnr Escherichia coli CFT073 fumarate/nitrate reduction transcriptional regulator NP_753709.2 1640861 R 199310 CDS NP_753710.1 26247670 1035598 complement(1641808..1642323) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1335; Escherichia coli O157:H7 ortholog: z2432; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1642323 ogt 1035598 ogt Escherichia coli CFT073 O-6-alkylguanine-DNA:cysteine-protein methyltransferase NP_753710.1 1641808 R 199310 CDS NP_753711.1 26247671 1035599 complement(1642334..1642525) 1 NC_004431.1 Residues 14 to 63 of 63 are 75.92 pct identical to residues 179 to 230 of 230 from GenPept.129 : >gb|AAG56464.1|AE005372_9 (AE005372) partial pump protein; disrupted by IS629 [Escherichia coli O157:H7 EDL933]; hypothetical protein 1642525 1035599 c1809 Escherichia coli CFT073 hypothetical protein NP_753711.1 1642334 R 199310 CDS NP_753712.1 26247672 1035600 complement(1642836..1643651) 1 NC_004431.1 Residues 10 to 258 of 271 are 35.34 pct identical to residues 18 to 260 of 268 from GenPept.129 : >emb|CAD16771.1| (AL646073) PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum]; hypothetical protein 1643651 1035600 c1810 Escherichia coli CFT073 hypothetical protein NP_753712.1 1642836 R 199310 CDS NP_753713.1 26247673 1035602 1643745..1644053 1 NC_004431.1 Residues 14 to 89 of 102 are 51.31 pct identical to residues 37 to 111 of 367 from GenPept.129 : >dbj|BAB49683.1| (AP003000) probable secretion protein [Mesorhizobium loti]; hypothetical protein 1644053 1035602 c1811 Escherichia coli CFT073 hypothetical protein NP_753713.1 1643745 D 199310 CDS NP_753714.1 26247674 1035603 1644038..1644436 1 NC_004431.1 Residues 1 to 126 of 132 are 46.03 pct identical to residues 378 to 503 of 518 from GenPept.129 : >dbj|BAB49682.1| (AP003000) probable transporter [Mesorhizobium loti]; hypothetical protein 1644436 1035603 c1812 Escherichia coli CFT073 hypothetical protein NP_753714.1 1644038 D 199310 CDS NP_753715.1 26247675 1035612 complement(1644184..1644312) 1 NC_004431.1 hypothetical protein 1644312 1035612 c1813 Escherichia coli CFT073 hypothetical protein NP_753715.1 1644184 R 199310 CDS NP_753716.1 26247676 1035614 1644631..1645194 1 NC_004431.1 Escherichia coli K-12 ortholog: b1340; Escherichia coli O157:H7 ortholog: z2422; hypothetical protein 1645194 ydaL 1035614 ydaL Escherichia coli CFT073 hypothetical protein NP_753716.1 1644631 D 199310 CDS NP_753717.1 26247677 1035615 complement(1645215..1646507) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1341; Escherichia coli O157:H7 ortholog: z2421; hypothetical protein 1646507 ydaM 1035615 ydaM Escherichia coli CFT073 hypothetical protein NP_753717.1 1645215 R 199310 CDS NP_753718.1 26247678 1035618 1646702..1647685 1 NC_004431.1 Escherichia coli K-12 ortholog: b1342; Escherichia coli O157:H7 ortholog: z2419; zinc transporter 1647685 zntB 1035618 zntB Escherichia coli CFT073 zinc transporter NP_753718.1 1646702 D 199310 CDS NP_753719.1 26247679 1035619 1648163..1649536 1 NC_004431.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1649536 dbpA 1035619 dbpA Escherichia coli CFT073 ATP-dependent RNA helicase DbpA NP_753719.1 1648163 D 199310 CDS NP_753720.1 26247680 1035620 complement(1649665..1650600) 1 NC_004431.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1650600 ydaO 1035620 ydaO Escherichia coli CFT073 C32 tRNA thiolase NP_753720.1 1649665 R 199310 CDS NP_753721.1 26247681 1035621 complement(1650652..1650960) 1 NC_004431.1 Residues 27 to 102 of 102 are 98.68 pct identical to residues 336 to 411 of 411 from MG1655 : b1345; hypothetical protein 1650960 1035621 c1819 Escherichia coli CFT073 hypothetical protein NP_753721.1 1650652 R 199310 CDS NP_753722.1 26247682 1035623 complement(1652469..1652837) 1 NC_004431.1 Residues 4 to 90 of 122 are 72.41 pct identical to residues 18 to 104 of 282 from GenPept.129 : >gb|AAL21744.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]; hypothetical protein 1652837 1035623 c1820 Escherichia coli CFT073 hypothetical protein NP_753722.1 1652469 R 199310 CDS NP_753723.1 26247683 1035624 complement(1652926..1653432) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1376; Escherichia coli O157:H7 ortholog: z2335; hypothetical protein 1653432 ynaF 1035624 ynaF Escherichia coli CFT073 hypothetical protein NP_753723.1 1652926 R 199310 CDS NP_753724.1 26247684 1035625 complement(1653501..1654634) 1 NC_004431.1 Porin ompN; Escherichia coli K-12 ortholog: b1377; Escherichia coli O157:H7 ortholog: z2334; outer membrane protein N 1654634 ompN 1035625 ompN Escherichia coli CFT073 outer membrane protein N NP_753724.1 1653501 R 199310 CDS NP_753725.1 26247685 1035626 complement(1655000..1658524) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332; pyruvate-flavodoxin oxidoreductase 1658524 ydbK 1035626 ydbK Escherichia coli CFT073 pyruvate-flavodoxin oxidoreductase NP_753725.1 1655000 R 199310 CDS NP_753726.1 26247686 1035627 complement(1658595..1658930) 1 NC_004431.1 Residues 18 to 85 of 111 are 52.94 pct identical to residues 2 to 69 of 99 from GenPept.129 : >gb|AAL20568.1| (AE008773) reverse transcriptase [Salmonella typhimurium LT2]; hypothetical protein 1658930 1035627 c1824 Escherichia coli CFT073 hypothetical protein NP_753726.1 1658595 R 199310 CDS NP_753727.1 26247687 1035628 1658909..1659064 1 NC_004431.1 Residues 1 to 51 of 51 are 100.00 pct identical to residues 1 to 51 of 51 from GenPept.129 : >dbj|BAA14988.1| (D90776) ORF_ID:o264#6; similar to [SwissProt Accession Number P52646] [Escherichia coli]; hypothetical protein 1659064 1035628 c1825 Escherichia coli CFT073 hypothetical protein NP_753727.1 1658909 D 199310 CDS NP_753728.1 26247688 1035629 complement(1659061..1659495) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1379; Escherichia coli O157:H7 ortholog: z2330; heat-inducible protein 1659495 hslJ 1035629 hslJ Escherichia coli CFT073 heat-inducible protein NP_753728.1 1659061 R 199310 CDS NP_753729.1 26247689 1035630 complement(1659594..1660583) 1 NC_004431.1 Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase 1660583 ldhA 1035630 ldhA Escherichia coli CFT073 D-lactate dehydrogenase NP_753729.1 1659594 R 199310 CDS NP_753730.1 26247690 1035631 1660791..1663430 1 NC_004431.1 Escherichia coli K-12 ortholog: b1381; Escherichia coli O157:H7 ortholog: z2328; hypothetical protein 1663430 ydbH 1035631 ydbH Escherichia coli CFT073 hypothetical protein NP_753730.1 1660791 D 199310 CDS NP_753731.1 26247691 1035632 1663427..1663612 1 NC_004431.1 Escherichia coli K-12 ortholog: b1382; Escherichia coli O157:H7 ortholog: z2327; hypothetical protein 1663612 ynbE 1035632 ynbE Escherichia coli CFT073 hypothetical protein NP_753731.1 1663427 D 199310 CDS NP_753732.1 26247692 1035633 1663587..1663946 1 NC_004431.1 Escherichia coli K-12 ortholog: b1383; Escherichia coli O157:H7 ortholog: z2326; hypothetical protein 1663946 ydbL 1035633 ydbL Escherichia coli CFT073 hypothetical protein NP_753732.1 1663587 D 199310 CDS NP_753733.1 26247693 1035636 1670579..1671439 1 NC_004431.1 Escherichia coli K-12 ortholog: b1406; Escherichia coli O157:H7 ortholog: z2321; oxidoreductase 1671439 ydbC 1035636 ydbC Escherichia coli CFT073 oxidoreductase NP_753733.1 1670579 D 199310 CDS NP_753734.1 26247694 1035637 complement(1671484..1671708) 1 NC_004431.1 hypothetical protein 1671708 1035637 c1833 Escherichia coli CFT073 hypothetical protein NP_753734.1 1671484 R 199310 CDS NP_753735.1 26247695 1035639 1671738..1672343 1 NC_004431.1 Escherichia coli K-12 ortholog: b1408; Escherichia coli O157:H7 ortholog: z2319; hypothetical protein 1672343 ynbA 1035639 ynbA Escherichia coli CFT073 hypothetical protein NP_753735.1 1671738 D 199310 CDS NP_753736.1 26247696 1035640 1672343..1673239 1 NC_004431.1 Escherichia coli K-12 ortholog: b1409; Escherichia coli O157:H7 ortholog: z2318; hypothetical protein 1673239 ynbB 1035640 ynbB Escherichia coli CFT073 hypothetical protein NP_753736.1 1672343 D 199310 CDS NP_753737.1 26247697 1035641 1673255..1675012 1 NC_004431.1 Escherichia coli K-12 ortholog: b1410; Escherichia coli O157:H7 ortholog: z2317; hypothetical protein 1675012 ynbC 1035641 ynbC Escherichia coli CFT073 hypothetical protein NP_753737.1 1673255 D 199310 CDS NP_753738.1 26247698 1035642 1674927..1676318 1 NC_004431.1 Escherichia coli K-12 ortholog: b1411; Escherichia coli O157:H7 ortholog: z2316; hypothetical protein 1676318 ynbD 1035642 ynbD Escherichia coli CFT073 hypothetical protein NP_753738.1 1674927 D 199310 CDS NP_753739.1 26247699 1035643 1676303..1676965 1 NC_004431.1 hypothetical protein 1676965 1035643 c1838 Escherichia coli CFT073 hypothetical protein NP_753739.1 1676303 D 199310 CDS NP_753740.1 26247700 1035644 complement(1676372..1676977) 1 NC_004431.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1676977 acpD 1035644 acpD Escherichia coli CFT073 azoreductase NP_753740.1 1676372 R 199310 CDS NP_753741.2 161486233 1035645 1677235..1681080 1 NC_004431.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1681080 hrpA 1035645 hrpA Escherichia coli CFT073 ATP-dependent RNA helicase HrpA NP_753741.2 1677235 D 199310 CDS NP_753742.1 26247702 1035647 1681353..1682153 1 NC_004431.1 Escherichia coli K-12 ortholog: b1414; Escherichia coli O157:H7 ortholog: z2308; hypothetical protein 1682153 ydcF 1035647 ydcF Escherichia coli CFT073 hypothetical protein NP_753742.1 1681353 D 199310 CDS NP_753743.1 26247703 1035648 1682350..1683789 1 NC_004431.1 NAD-linked; aldehyde dehydrogenase 1683789 aldA 1035648 aldA Escherichia coli CFT073 aldehyde dehydrogenase NP_753743.1 1682350 D 199310 CDS NP_753744.1 26247704 1035649 complement(1683831..1684832) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1779; Escherichia coli O157:H7 ortholog: z2304; glyceraldehyde 3-phosphate dehydrogenase A 1684832 1035649 c1843 Escherichia coli CFT073 glyceraldehyde 3-phosphate dehydrogenase A NP_753744.1 1683831 R 199310 CDS NP_753745.2 161486232 1035650 1685021..1685551 1 NC_004431.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1685551 cybB 1035650 cybB Escherichia coli CFT073 cytochrome b561 NP_753745.2 1685021 D 199310 CDS NP_753746.1 26247706 1035654 1685796..1685969 1 NC_004431.1 Escherichia coli K-12 ortholog: b1419; Escherichia coli O157:H7 ortholog: z2302; hypothetical protein 1685969 ydcA 1035654 ydcA Escherichia coli CFT073 hypothetical protein NP_753746.1 1685796 D 199310 CDS NP_753747.1 26247707 1035656 1686126..1686596 1 NC_004431.1 Residues 10 to 156 of 156 are 95.91 pct identical to residues 400 to 546 of 546 from MG1655 : b1421; hypothetical protein 1686596 1035656 c1846 Escherichia coli CFT073 hypothetical protein NP_753747.1 1686126 D 199310 CDS NP_753748.1 26247708 1035658 complement(1686634..1687698) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1422; Escherichia coli O157:H7 ortholog: z2299; transcriptional regulator YdcI 1687698 ycdI 1035658 ycdI Escherichia coli CFT073 transcriptional regulator YdcI NP_753748.1 1686634 R 199310 CDS NP_753749.1 26247709 1035659 1687774..1689117 1 NC_004431.1 Escherichia coli K-12 ortholog: b1423; hypothetical protein 1689117 ydcJ 1035659 ydcJ Escherichia coli CFT073 hypothetical protein NP_753749.1 1687774 D 199310 CDS NP_753750.1 26247710 1035660 1689342..1690997 1 NC_004431.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1690997 mdoD 1035660 mdoD Escherichia coli CFT073 glucan biosynthesis protein D NP_753750.1 1689342 D 199310 CDS NP_753751.1 26247711 1035661 1691131..1691361 1 NC_004431.1 Escherichia coli K-12 ortholog: b1426; Escherichia coli O157:H7 ortholog: z2292; hypothetical protein 1691361 ydcH 1035661 ydcH Escherichia coli CFT073 hypothetical protein NP_753751.1 1691131 D 199310 CDS NP_753752.1 26247712 1035663 1691409..1691963 1 NC_004431.1 Escherichia coli K-12 ortholog: b1427; ribosomal-protein-L7/L12-serine acetyltransferase 1691963 rimL 1035663 rimL Escherichia coli CFT073 ribosomal-protein-L7/L12-serine acetyltransferase NP_753752.1 1691409 D 199310 CDS NP_753753.1 26247713 1035665 complement(1691955..1692935) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1428; Escherichia coli O157:H7 ortholog: z2290; hypothetical protein 1692935 ydcK 1035665 ydcK Escherichia coli CFT073 hypothetical protein NP_753753.1 1691955 R 199310 CDS NP_753754.1 26247714 1035674 1692951..1694051 1 NC_004431.1 Escherichia coli K-12 ortholog: b1429; Escherichia coli O157:H7 ortholog: z2289; potassium-tellurite ethidium and proflavin transporter 1694051 tehA 1035674 tehA Escherichia coli CFT073 potassium-tellurite ethidium and proflavin transporter NP_753754.1 1692951 D 199310 CDS NP_753755.1 26247715 1035675 1694048..1694641 1 NC_004431.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1694641 tehB 1035675 tehB Escherichia coli CFT073 tellurite resistance protein TehB NP_753755.1 1694048 D 199310 CDS NP_753756.1 26247716 1035676 complement(1694925..1695053) 1 NC_004431.1 hypothetical protein 1695053 1035676 c1855 Escherichia coli CFT073 hypothetical protein NP_753756.1 1694925 R 199310 CDS NP_753757.1 26247717 1035680 1694944..1695612 1 NC_004431.1 Escherichia coli K-12 ortholog: b1431; Escherichia coli O157:H7 ortholog: z2287; lipoprotein ydcL 1695612 ydcL 1035680 ydcL Escherichia coli CFT073 lipoprotein ydcL NP_753757.1 1694944 D 199310 CDS NP_753758.1 26247718 1035681 complement(1695647..1696942) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1433; Escherichia coli O157:H7 ortholog: z2286; hypothetical protein 1696942 ydcO 1035681 ydcO Escherichia coli CFT073 hypothetical protein NP_753758.1 1695647 R 199310 CDS NP_753759.1 26247719 1035682 1696911..1697447 1 NC_004431.1 Escherichia coli K-12 ortholog: b1434; Escherichia coli O157:H7 ortholog: z2285; hypothetical protein 1697447 ydcN 1035682 ydcN Escherichia coli CFT073 hypothetical protein NP_753759.1 1696911 D 199310 CDS NP_753760.1 26247720 1035683 1697478..1699481 1 NC_004431.1 Escherichia coli K-12 ortholog: b1435; Escherichia coli O157:H7 ortholog: z2284; protease ydcP 1699481 ydcP 1035683 ydcP Escherichia coli CFT073 protease ydcP NP_753760.1 1697478 D 199310 CDS NP_753761.1 26247721 1035684 complement(1699573..1699803) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1436; Escherichia coli O157:H7 ortholog: z2283; hypothetical protein 1699803 yncJ 1035684 yncJ Escherichia coli CFT073 hypothetical protein NP_753761.1 1699573 R 199310 CDS NP_753762.1 26247722 1035685 complement(1699860..1699988) 1 NC_004431.1 hypothetical protein 1699988 1035685 c1861 Escherichia coli CFT073 hypothetical protein NP_753762.1 1699860 R 199310 CDS NP_753763.1 26247723 1035686 1700015..1700218 1 NC_004431.1 Residues 1 to 67 of 67 are 95.52 pct identical to residues 79 to 145 of 145 from GenPept.129 : >gb|AAC74520.1| (AE000241) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 1700218 1035686 c1862 Escherichia coli CFT073 hypothetical protein NP_753763.1 1700015 D 199310 CDS NP_753764.1 26247724 1035688 1700297..1701703 1 NC_004431.1 Escherichia coli K-12 ortholog: b1439; Escherichia coli O157:H7 ortholog: z2280; hypothetical protein 1701703 ydcR 1035688 ydcR Escherichia coli CFT073 hypothetical protein NP_753764.1 1700297 D 199310 CDS NP_753765.1 26247725 1035689 1701948..1703093 1 NC_004431.1 Escherichia coli K-12 ortholog: b1440; Escherichia coli O157:H7 ortholog: z2279; ABC transporter periplasmic-binding protein 1703093 ydcS 1035689 ydcS Escherichia coli CFT073 ABC transporter periplasmic-binding protein NP_753765.1 1701948 D 199310 CDS NP_753766.1 26247726 1035690 1703111..1704124 1 NC_004431.1 Escherichia coli K-12 ortholog: b1441; Escherichia coli O157:H7 ortholog: z2278; ABC transporter ATP-binding protein 1704124 ydcT 1035690 ydcT Escherichia coli CFT073 ABC transporter ATP-binding protein NP_753766.1 1703111 D 199310 CDS NP_753767.1 26247727 1035691 1704125..1705066 1 NC_004431.1 Escherichia coli K-12 ortholog: b1442; Escherichia coli O157:H7 ortholog: z2277; ABC transporter permease 1705066 ydcU 1035691 ydcU Escherichia coli CFT073 ABC transporter permease NP_753767.1 1704125 D 199310 CDS NP_753768.1 26247728 1035693 1705056..1705700 1 NC_004431.1 Escherichia coli K-12 ortholog: b1443; Escherichia coli O157:H7 ortholog: z2276; ABC transporter permease 1705700 ydcV 1035693 ydcV Escherichia coli CFT073 ABC transporter permease NP_753768.1 1705056 D 199310 CDS NP_753769.1 26247729 1035695 1705873..1707297 1 NC_004431.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1707297 ydcW 1035695 ydcW Escherichia coli CFT073 gamma-aminobutyraldehyde dehydrogenase NP_753769.1 1705873 D 199310 CDS NP_753770.1 26247730 1035696 1707609..1707857 1 NC_004431.1 Escherichia coli K-12 ortholog: b1445; Escherichia coli O157:H7 ortholog: z2274; hypothetical protein 1707857 1035696 c1870 Escherichia coli CFT073 hypothetical protein NP_753770.1 1707609 D 199310 CDS NP_753771.1 26247731 1035697 1707943..1708176 1 NC_004431.1 Escherichia coli K-12 ortholog: b1446; Escherichia coli O157:H7 ortholog: z2273; hypothetical protein 1708176 ydc 1035697 ydc Escherichia coli CFT073 hypothetical protein NP_753771.1 1707943 D 199310 CDS NP_753772.1 26247732 1035698 complement(1708177..1708626) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1447; Escherichia coli O157:H7 ortholog: z2272; hypothetical protein 1708626 ydcZ 1035698 ydcZ Escherichia coli CFT073 hypothetical protein NP_753772.1 1708177 R 199310 CDS NP_753773.1 26247733 1035699 complement(1708623..1709204) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1448; Escherichia coli O157:H7 ortholog: z2271; acetyltransferase yncA 1709204 yncA 1035699 yncA Escherichia coli CFT073 acetyltransferase yncA NP_753773.1 1708623 R 199310 CDS NP_753774.1 26247734 1035700 1709348..1709584 1 NC_004431.1 Residues 11 to 66 of 78 are 89.28 pct identical to residues 71 to 126 of 240 from MG1655 : b1450; hypothetical protein 1709584 1035700 c1874 Escherichia coli CFT073 hypothetical protein NP_753774.1 1709348 D 199310 CDS NP_753775.1 26247735 1035703 1711967..1713028 1 NC_004431.1 Escherichia coli K-12 ortholog: b1452; Escherichia coli O157:H7 ortholog: z2267; hypothetical protein 1713028 yncE 1035703 yncE Escherichia coli CFT073 hypothetical protein NP_753775.1 1711967 D 199310 CDS NP_753776.1 26247736 1035705 complement(1713141..1714691) 1 NC_004431.1 L-asparagine transport protein; Escherichia coli K-12 ortholog: b1453; Escherichia coli O157:H7 ortholog: z2266; L-asparagine permease 1714691 ansP 1035705 ansP Escherichia coli CFT073 L-asparagine permease NP_753776.1 1713141 R 199310 CDS NP_753777.1 26247737 1035706 1714907..1715083 1 NC_004431.1 Residues 1 to 58 of 58 are 96.55 pct identical to residues 1 to 58 of 205 from GenPept.129 : >gb|AAG56321.1|AE005361_2 (AE005361) transferase [Escherichia coli O157:H7 EDL933]; hypothetical protein 1715083 1035706 c1879 Escherichia coli CFT073 hypothetical protein NP_753777.1 1714907 D 199310 CDS NP_753778.1 26247738 1035708 1715196..1715525 1 NC_004431.1 Residues 1 to 109 of 109 are 90.82 pct identical to residues 97 to 205 of 205 from MG1655 : b1454; hypothetical protein 1715525 1035708 c1880 Escherichia coli CFT073 hypothetical protein NP_753778.1 1715196 D 199310 CDS NP_753779.1 26247739 1035713 complement(1715945..1716094) 1 NC_004431.1 hypothetical protein 1716094 1035713 c1881 Escherichia coli CFT073 hypothetical protein NP_753779.1 1715945 R 199310 CDS NP_753780.1 26247740 1035719 1716066..1716350 1 NC_004431.1 Residues 11 to 94 of 94 are 67.85 pct identical to residues 11 to 94 of 94 from GenPept.129 : >gb|AAF96019.1| (AE004353) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 1716350 1035719 c1882 Escherichia coli CFT073 hypothetical protein NP_753780.1 1716066 D 199310 CDS NP_753781.1 26247741 1035722 1716369..1718327 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0707; hypothetical protein 1718327 1035722 c1883 Escherichia coli CFT073 hypothetical protein NP_753781.1 1716369 D 199310 CDS NP_753782.1 26247742 1035724 1718427..1719167 1 NC_004431.1 hypothetical protein 1719167 1035724 c1884 Escherichia coli CFT073 hypothetical protein NP_753782.1 1718427 D 199310 CDS NP_753783.1 26247743 1035729 1719505..1720740 1 NC_004431.1 hypothetical protein 1720740 1035729 c1885 Escherichia coli CFT073 hypothetical protein NP_753783.1 1719505 D 199310 CDS NP_753784.1 26247744 1035730 1720751..1721794 1 NC_004431.1 hypothetical protein 1721794 1035730 c1886 Escherichia coli CFT073 hypothetical protein NP_753784.1 1720751 D 199310 CDS NP_753785.1 26247745 1035731 1721906..1722190 1 NC_004431.1 Residues 11 to 94 of 94 are 66.66 pct identical to residues 11 to 94 of 94 from GenPept.129 : >gb|AAF96019.1| (AE004353) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 1722190 1035731 c1887 Escherichia coli CFT073 hypothetical protein NP_753785.1 1721906 D 199310 CDS NP_753786.1 26247746 1035735 1722209..1724614 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0267; hypothetical protein 1724614 1035735 c1888 Escherichia coli CFT073 hypothetical protein NP_753786.1 1722209 D 199310 CDS NP_753787.1 26247747 1035747 1724601..1725203 1 NC_004431.1 hypothetical protein 1725203 1035747 c1889 Escherichia coli CFT073 hypothetical protein NP_753787.1 1724601 D 199310 CDS NP_753788.1 26247748 1035748 1725540..1725992 1 NC_004431.1 hypothetical protein 1725992 1035748 c1890 Escherichia coli CFT073 hypothetical protein NP_753788.1 1725540 D 199310 CDS NP_753789.1 26247749 1035772 1726211..1726717 1 NC_004431.1 hypothetical protein 1726717 1035772 c1891 Escherichia coli CFT073 hypothetical protein NP_753789.1 1726211 D 199310 CDS NP_753790.1 26247750 1035775 1726714..1727181 1 NC_004431.1 hypothetical protein 1727181 1035775 c1892 Escherichia coli CFT073 hypothetical protein NP_753790.1 1726714 D 199310 CDS NP_753791.1 26247751 1035790 1727294..1727437 1 NC_004431.1 Residues 1 to 47 of 47 are 87.23 pct identical to residues 68 to 114 of 203 from GenPept.129 : >gb|AAG56311.1|AE005360_3 (AE005360) H repeat-associated protein of Rhs element [Escherichia coli O157:H7 EDL933]; hypothetical protein 1727437 1035790 c1893 Escherichia coli CFT073 hypothetical protein NP_753791.1 1727294 D 199310 CDS NP_753792.1 26247752 1035791 complement(1728047..1728616) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1462; Escherichia coli O157:H7 ortholog: z2251; hypothetical protein 1728616 yddH 1035791 yddH Escherichia coli CFT073 hypothetical protein NP_753792.1 1728047 R 199310 CDS NP_753793.1 26247753 1035792 1728791..1729636 1 NC_004431.1 Escherichia coli K-12 ortholog: b1463; Escherichia coli O157:H7 ortholog: z2250; N-hydroxyarylamine O-acetyltransferase 1729636 nhoA 1035792 nhoA Escherichia coli CFT073 N-hydroxyarylamine O-acetyltransferase NP_753793.1 1728791 D 199310 CDS NP_753794.1 26247754 1035794 complement(1729732..1730625) 1 NC_004431.1 ORFB; Escherichia coli K-12 ortholog: b1464; Escherichia coli O157:H7 ortholog: z2248; hypothetical protein 1730625 yddE 1035794 yddE Escherichia coli CFT073 hypothetical protein NP_753794.1 1729732 R 199310 CDS NP_753795.1 26247755 1035796 complement(1730705..1731385) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1465; Escherichia coli O157:H7 ortholog: z2247; respiratory nitrate reductase 2 subunit gamma 1731385 narV 1035796 narV Escherichia coli CFT073 respiratory nitrate reductase 2 subunit gamma NP_753795.1 1730705 R 199310 CDS NP_753796.1 26247756 1035798 complement(1731382..1732077) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1466; Escherichia coli O157:H7 ortholog: z2246; respiratory nitrate reductase 2 subunit delta 1732077 narW 1035798 narW Escherichia coli CFT073 respiratory nitrate reductase 2 subunit delta NP_753796.1 1731382 R 199310 CDS NP_753797.1 26247757 1035799 complement(1732077..1733621) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1467; Escherichia coli O157:H7 ortholog: z2245; respiratory nitrate reductase 2 subunit beta 1733621 narY 1035799 narY Escherichia coli CFT073 respiratory nitrate reductase 2 subunit beta NP_753797.1 1732077 R 199310 CDS NP_753798.1 26247758 1035800 complement(1733618..1737481) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1468; Escherichia coli O157:H7 ortholog: z2244; respiratory nitrate reductase 2 subunit alpha 1737481 narZ 1035800 narZ Escherichia coli CFT073 respiratory nitrate reductase 2 subunit alpha NP_753798.1 1733618 R 199310 CDS NP_753799.1 26247759 1035801 complement(1737453..1738841) 1 NC_004431.1 Nitrite facilitator 2; Escherichia coli K-12 ortholog: b1469; Escherichia coli O157:H7 ortholog: z2243; nitrite extrusion protein 2 1738841 narU 1035801 narU Escherichia coli CFT073 nitrite extrusion protein 2 NP_753799.1 1737453 R 199310 CDS NP_753800.1 26247760 1035805 complement(1739114..1739995) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1473; Escherichia coli O157:H7 ortholog: z2238; hypothetical protein 1739995 yddG 1035805 yddG Escherichia coli CFT073 hypothetical protein NP_753800.1 1739114 R 199310 CDS NP_753801.1 26247761 1035806 1740228..1743275 1 NC_004431.1 Escherichia coli K-12 ortholog: b1474; Escherichia coli O157:H7 ortholog: z2236; formate dehydrogenase, nitrate-inducible, major subunit 1743275 fdnG 1035806 fdnG Escherichia coli CFT073 formate dehydrogenase, nitrate-inducible, major subunit NP_753801.1 1740228 D 199310 CDS NP_753802.1 26247762 1035807 complement(1743252..1744196) 1 NC_004431.1 hypothetical protein 1744196 1035807 c1905 Escherichia coli CFT073 hypothetical protein NP_753802.1 1743252 R 199310 CDS NP_753803.1 26247763 1035808 1743288..1744172 1 NC_004431.1 Nitrate-inducible; Iron-sulfur subunit; Escherichia coli K-12 ortholog: b1475; Escherichia coli O157:H7 ortholog: z2235; formate dehydrogenase-N beta subunit 1744172 fdnH 1035808 fdnH Escherichia coli CFT073 formate dehydrogenase-N beta subunit NP_753803.1 1743288 D 199310 CDS NP_753804.1 26247764 1035811 1744165..1744818 1 NC_004431.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1744818 fdnI 1035811 fdnI Escherichia coli CFT073 formate dehydrogenase-N subunit gamma NP_753804.1 1744165 D 199310 CDS NP_753805.1 26247765 1035812 1745018..1745290 1 NC_004431.1 hypothetical protein 1745290 1035812 c1908 Escherichia coli CFT073 hypothetical protein NP_753805.1 1745018 D 199310 CDS NP_753806.1 26247766 1035813 complement(1745044..1745328) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1477; Escherichia coli O157:H7 ortholog: z2233; hypothetical protein 1745328 yddM 1035813 yddM Escherichia coli CFT073 hypothetical protein NP_753806.1 1745044 R 199310 CDS NP_753807.1 26247767 1035815 complement(1745328..1745600) 1 NC_004431.1 Residues 2 to 90 of 90 are 56.17 pct identical to residues 4 to 92 of 92 from GenPept.129 : >gb|AAC43982.1| (U43847) killer protein [Plasmid Rts1]; hypothetical protein 1745600 1035815 c1910 Escherichia coli CFT073 hypothetical protein NP_753807.1 1745328 R 199310 CDS NP_753808.2 161486231 1035817 complement(1745792..1746802) 1 NC_004431.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1746802 adhP 1035817 adhP Escherichia coli CFT073 alcohol dehydrogenase NP_753808.2 1745792 R 199310 CDS NP_753809.2 229106381 1035818 complement(1746936..1748633) 1 NC_004431.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1748633 sfcA 1035818 sfcA Escherichia coli CFT073 malate dehydrogenase NP_753809.2 1746936 R 199310 CDS NP_753810.1 26247770 1035819 complement(1748790..1748927) 1 NC_004431.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 1748927 rpsV 1035819 rpsV Escherichia coli CFT073 30S ribosomal subunit S22 NP_753810.1 1748790 R 199310 CDS NP_753811.2 161486230 1035821 complement(1749029..1749244) 1 NC_004431.1 Biofilm-dependent modulation protein; Escherichia coli K-12 ortholog: b1481; Escherichia coli O157:H7 ortholog: z2229; biofilm-dependent modulation protein 1749244 1035821 c1914 Escherichia coli CFT073 biofilm-dependent modulation protein NP_753811.2 1749029 R 199310 CDS NP_753812.1 26247772 1035823 1749411..1749551 1 NC_004431.1 hypothetical protein 1749551 1035823 c1915 Escherichia coli CFT073 hypothetical protein NP_753812.1 1749411 D 199310 CDS NP_753813.1 26247773 1035827 1749589..1750020 1 NC_004431.1 Escherichia coli K-12 ortholog: b1482; Escherichia coli O157:H7 ortholog: z2228; osmotically inducible protein C 1750020 osmC 1035827 osmC Escherichia coli CFT073 osmotically inducible protein C NP_753813.1 1749589 D 199310 CDS NP_753814.1 26247774 1035829 complement(1751294..1752634) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2220; sensor kinase 1752634 1035829 c1918 Escherichia coli CFT073 sensor kinase NP_753814.1 1751294 R 199310 CDS NP_753815.1 26247775 1035831 complement(1752635..1752853) 1 NC_004431.1 Residues 19 to 72 of 72 are 98.14 pct identical to residues 407 to 460 of 460 from MG1655 : b1490; hypothetical protein 1752853 1035831 c1919 Escherichia coli CFT073 hypothetical protein NP_753815.1 1752635 R 199310 CDS NP_753816.1 26247776 1035836 complement(1753177..1754496) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1491; Escherichia coli O157:H7 ortholog: z2217; lipoprotein yddW 1754496 yddW 1035836 yddW Escherichia coli CFT073 lipoprotein yddW NP_753816.1 1753177 R 199310 CDS NP_753817.1 26247777 1035837 complement(1754627..1756162) 1 NC_004431.1 Extreme acid sensitivity protein; Escherichia coli K-12 ortholog: b1492; Escherichia coli O157:H7 ortholog: z2216; amino acid antiporter 1756162 xasA 1035837 xasA Escherichia coli CFT073 amino acid antiporter NP_753817.1 1754627 R 199310 CDS NP_753818.1 26247778 1035839 complement(1756318..1757787) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1493; Escherichia coli O157:H7 ortholog: z2215; glutamate decarboxylase beta 1757787 gadB 1035839 gadB Escherichia coli CFT073 glutamate decarboxylase beta NP_753818.1 1756318 R 199310 CDS NP_753819.1 26247779 1035840 complement(1758079..1760874) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1494; Escherichia coli O157:H7 ortholog: z2214; zinc protease pqqL 1760874 pqqL 1035840 pqqL Escherichia coli CFT073 zinc protease pqqL NP_753819.1 1758079 R 199310 CDS NP_753820.1 26247780 1035841 complement(1760919..1763291) 1 NC_004431.1 CDS103; Escherichia coli K-12 ortholog: b1495; Escherichia coli O157:H7 ortholog: z2213; hypothetical protein 1763291 yddB 1035841 yddB Escherichia coli CFT073 hypothetical protein NP_753820.1 1760919 R 199310 CDS NP_753821.1 26247781 1035844 complement(1763329..1765014) 1 NC_004431.1 CDS102; Escherichia coli K-12 ortholog: b1496; Escherichia coli O157:H7 ortholog: z2212; ABC transporter ATP-binding protein 1765014 yddA 1035844 yddA Escherichia coli CFT073 ABC transporter ATP-binding protein NP_753821.1 1763329 R 199310 CDS NP_753822.1 26247782 1035845 complement(1765305..1766477) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1497; Escherichia coli O157:H7 ortholog: z2211; hypothetical protein 1766477 ydeM 1035845 ydeM Escherichia coli CFT073 hypothetical protein NP_753822.1 1765305 R 199310 CDS NP_753823.1 26247783 1035847 complement(1766514..1768229) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1498; Escherichia coli O157:H7 ortholog: z2210; sulfatase ydeN 1768229 ydeN 1035847 ydeN Escherichia coli CFT073 sulfatase ydeN NP_753823.1 1766514 R 199310 CDS NP_753824.1 26247784 1035848 complement(1768598..1769359) 1 NC_004431.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1769359 ydeO 1035848 ydeO Escherichia coli CFT073 transcriptional regulator YdeO NP_753824.1 1768598 R 199310 CDS NP_753825.1 26247785 1035849 complement(1769435..1769632) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1500; Escherichia coli O157:H7 ortholog: z2208; hypothetical protein 1769632 1035849 c1929 Escherichia coli CFT073 hypothetical protein NP_753825.1 1769435 R 199310 CDS NP_753826.1 26247786 1035851 complement(1769880..1772159) 1 NC_004431.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase 1772159 ydeP 1035851 ydeP Escherichia coli CFT073 oxidoreductase NP_753826.1 1769880 R 199310 CDS NP_753827.1 26247787 1035852 complement(1772498..1773412) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1502; Escherichia coli O157:H7 ortholog: z2206; fimbrial-like protein ydeQ 1773412 ydeQ 1035852 ydeQ Escherichia coli CFT073 fimbrial-like protein ydeQ NP_753827.1 1772498 R 199310 CDS NP_753828.1 26247788 1035853 complement(1773472..1773975) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1503; Escherichia coli O157:H7 ortholog: z2205; fimbrial-like protein ydeR 1773975 ydeR 1035853 ydeR Escherichia coli CFT073 fimbrial-like protein ydeR NP_753828.1 1773472 R 199310 CDS NP_753829.1 26247789 1035854 complement(1773988..1774518) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1504; Escherichia coli O157:H7 ortholog: z2204; fimbrial-like protein ydeS 1774518 ydeS 1035854 ydeS Escherichia coli CFT073 fimbrial-like protein ydeS NP_753829.1 1773988 R 199310 CDS NP_753830.1 26247790 1035855 complement(1774532..1777183) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z2203; outer membrane usher protein fimD 1777183 1035855 c1934 Escherichia coli CFT073 outer membrane usher protein fimD NP_753830.1 1774532 R 199310 CDS NP_753831.1 26247791 1035856 complement(1777225..1777935) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z2201; chaperone protein fimC 1777935 1035856 c1935 Escherichia coli CFT073 chaperone protein fimC NP_753831.1 1777225 R 199310 CDS NP_753832.1 26247792 1035857 complement(1778297..1778908) 1 NC_004431.1 Type-1A pilin; Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z2200; Type-1 fimbrial protein, A chain 1778908 1035857 c1936 Escherichia coli CFT073 Type-1 fimbrial protein, A chain NP_753832.1 1778297 R 199310 CDS NP_753833.1 26247793 1035858 complement(1779636..1780418) 1 NC_004431.1 Residues 1 to 222 of 260 are 34.22 pct identical to residues 1 to 219 of 219 from GenPept.129 : >dbj|BAA18102.1| (D90911) ORF_ID:sll1218; hypothetical protein [Synechocystis sp. PCC 6803]; hypothetical protein 1780418 1035858 c1937 Escherichia coli CFT073 hypothetical protein NP_753833.1 1779636 R 199310 CDS NP_753834.1 26247794 1035859 1780528..1781475 1 NC_004431.1 Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 1781475 oprR 1035859 oprR Escherichia coli CFT073 transcriptional regulator YcjZ NP_753834.1 1780528 D 199310 CDS NP_753835.1 26247795 1035860 1781157..1781609 1 NC_004431.1 Residues 1 to 134 of 150 are 81.34 pct identical to residues 139 to 272 of 363 from GenPept.129 : >emb|CAC90815.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 1781609 1035860 c1939 Escherichia coli CFT073 hypothetical protein NP_753835.1 1781157 D 199310 CDS NP_753836.1 26247796 1035862 complement(1781779..1783197) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1507; Escherichia coli O157:H7 ortholog: z2197; protein hipA 1783197 hipA 1035862 hipA Escherichia coli CFT073 protein hipA NP_753836.1 1781779 R 199310 CDS NP_753837.1 26247797 1035865 complement(1783191..1783475) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1508; DNA-binding transcriptional regulator HipB 1783475 hipB 1035865 hipB Escherichia coli CFT073 DNA-binding transcriptional regulator HipB NP_753837.1 1783191 R 199310 CDS NP_753838.1 26247798 1035868 1783765..1784523 1 NC_004431.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1784523 tam 1035868 tam Escherichia coli CFT073 trans-aconitate 2-methyltransferase NP_753838.1 1783765 D 199310 CDS NP_753839.1 26247799 1035869 complement(1784527..1785492) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1520; Escherichia coli O157:H7 ortholog: z2185; hypothetical protein 1785492 yneE 1035869 yneE Escherichia coli CFT073 hypothetical protein NP_753839.1 1784527 R 199310 CDS NP_753840.1 26247800 1035871 complement(1787317..1788735) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1522; Escherichia coli O157:H7 ortholog: z2182; hypothetical protein 1788735 yneF 1035871 yneF Escherichia coli CFT073 hypothetical protein NP_753840.1 1787317 R 199310 CDS NP_753841.1 26247801 1035872 complement(1788874..1789233) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1523; Escherichia coli O157:H7 ortholog: z2180; hypothetical protein 1789233 yneG 1035872 yneG Escherichia coli CFT073 hypothetical protein NP_753841.1 1788874 R 199310 CDS NP_753842.1 26247802 1035873 complement(1789233..1790159) 1 NC_004431.1 catalyzes the formation of glutamate from glutamine; glutaminase 1790159 yneH 1035873 yneH Escherichia coli CFT073 glutaminase NP_753842.1 1789233 R 199310 CDS NP_753843.1 26247803 1035874 complement(1790223..1791635) 1 NC_004431.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1791635 yneI 1035874 yneI Escherichia coli CFT073 succinate semialdehyde dehydrogenase NP_753843.1 1790223 R 199310 CDS NP_753844.1 26247804 1035878 1791712..1792593 1 NC_004431.1 Escherichia coli K-12 ortholog: b1526; Escherichia coli O157:H7 ortholog: z2177; transcriptional regulator YneJ 1792593 yneJ 1035878 yneJ Escherichia coli CFT073 transcriptional regulator YneJ NP_753844.1 1791712 D 199310 CDS NP_753845.1 26247805 1035879 1792932..1794122 1 NC_004431.1 Escherichia coli K-12 ortholog: b1528; Escherichia coli O157:H7 ortholog: z2173; sugar efflux transporter 1794122 sotB 1035879 sotB Escherichia coli CFT073 sugar efflux transporter NP_753845.1 1792932 D 199310 CDS NP_753846.1 26247806 1035884 complement(1794147..1794812) 1 NC_004431.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1794812 marC 1035884 marC Escherichia coli CFT073 multiple drug resistance protein MarC NP_753846.1 1794147 R 199310 CDS NP_753847.1 26247807 1035885 1795024..1795458 1 NC_004431.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1795458 marR 1035885 marR Escherichia coli CFT073 DNA-binding transcriptional repressor MarR NP_753847.1 1795024 D 199310 CDS NP_753848.2 161486229 1035887 1795479..1795862 1 NC_004431.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1795862 marA 1035887 marA Escherichia coli CFT073 DNA-binding transcriptional activator MarA NP_753848.2 1795479 D 199310 CDS NP_753849.1 26247809 1035888 1795894..1796112 1 NC_004431.1 Escherichia coli K-12 ortholog: b1532; Escherichia coli O157:H7 ortholog: z2169; hypothetical protein 1796112 marB 1035888 marB Escherichia coli CFT073 hypothetical protein NP_753849.1 1795894 D 199310 CDS NP_753850.1 26247810 1035889 complement(1796169..1797614) 1 NC_004431.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 1797614 celA 1035889 celA Escherichia coli CFT073 6-phospho-beta-glucosidase NP_753850.1 1796169 R 199310 CDS NP_753851.1 26247811 1035894 complement(1797633..1799306) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3720; hypothetical protein 1799306 1035894 c1956 Escherichia coli CFT073 hypothetical protein NP_753851.1 1797633 R 199310 CDS NP_753852.1 26247812 1035897 complement(1799361..1799675) 1 NC_004431.1 EIIA-Cel; Escherichia coli K-12 ortholog: b1736; Escherichia coli O157:H7 ortholog: z2766; PTS system, cellobiose-specific IIA component 1799675 1035897 c1957 Escherichia coli CFT073 PTS system, cellobiose-specific IIA component NP_753852.1 1799361 R 199310 CDS NP_753853.1 26247813 1035898 complement(1799700..1801061) 1 NC_004431.1 Residues 17 to 448 of 453 are 36.79 pct identical to residues 1 to 435 of 452 from MG1655 : b1737; hypothetical protein 1801061 1035898 c1958 Escherichia coli CFT073 hypothetical protein NP_753853.1 1799700 R 199310 CDS NP_753854.1 26247814 1035900 complement(1801137..1801448) 1 NC_004431.1 EIIB-Cel; Escherichia coli K-12 ortholog: b1738; Escherichia coli O157:H7 ortholog: z2768; PTS system, cellobiose-specific IIB component 1801448 1035900 c1959 Escherichia coli CFT073 PTS system, cellobiose-specific IIB component NP_753854.1 1801137 R 199310 CDS NP_753855.1 26247815 1035901 1801647..1802345 1 NC_004431.1 Residues 1 to 232 of 232 are 35.77 pct identical to residues 1 to 232 of 238 from MG1655 : b3684; hypothetical protein 1802345 1035901 c1960 Escherichia coli CFT073 hypothetical protein NP_753855.1 1801647 D 199310 CDS NP_753856.2 161486228 1035904 complement(1802390..1803289) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1533; Escherichia coli O157:H7 ortholog: z2168; O-acetylserine/cysteine export protein 1803289 ydeD 1035904 ydeD Escherichia coli CFT073 O-acetylserine/cysteine export protein NP_753856.2 1802390 R 199310 CDS NP_753857.1 26247817 1035907 1803484..1804671 1 NC_004431.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1804671 ydeF 1035907 ydeF Escherichia coli CFT073 MFS-type transporter YdeE NP_753857.1 1803484 D 199310 CDS NP_753858.1 26247818 1035908 complement(1805113..1806009) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1535; Escherichia coli O157:H7 ortholog: z2163; hypothetical protein 1806009 ydeH 1035908 ydeH Escherichia coli CFT073 hypothetical protein NP_753858.1 1805113 R 199310 CDS NP_753859.1 26247819 1035911 complement(1806510..1808621) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1538; Escherichia coli O157:H7 ortholog: z2160; dipeptidyl carboxypeptidase II 1808621 dcp 1035911 dcp Escherichia coli CFT073 dipeptidyl carboxypeptidase II NP_753859.1 1806510 R 199310 CDS NP_753860.1 26247820 1035913 1808677..1809438 1 NC_004431.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1809438 ydfG 1035913 ydfG Escherichia coli CFT073 3-hydroxy acid dehydrogenase NP_753860.1 1808677 D 199310 CDS NP_753861.1 26247821 1035915 1809527..1810213 1 NC_004431.1 Escherichia coli K-12 ortholog: b1540; Escherichia coli O157:H7 ortholog: z2157; transcriptional regulator YdfH 1810213 ydfH 1035915 ydfH Escherichia coli CFT073 transcriptional regulator YdfH NP_753861.1 1809527 D 199310 CDS NP_753862.1 26247822 1035916 1810390..1810593 1 NC_004431.1 Escherichia coli K-12 ortholog: b1541; Escherichia coli O157:H7 ortholog: z2156; hypothetical protein 1810593 ydfZ 1035916 ydfZ Escherichia coli CFT073 hypothetical protein NP_753862.1 1810390 D 199310 CDS NP_753863.1 26247823 1035921 complement(1810629..1812089) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1542; Escherichia coli O157:H7 ortholog: z2155; oxidoreductase ydfI 1812089 1035921 c1968 Escherichia coli CFT073 oxidoreductase ydfI NP_753863.1 1810629 R 199310 CDS NP_753864.1 26247824 1035922 complement(1812178..1813545) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1543; Escherichia coli O157:H7 ortholog: z2153; metabolite transport protein 1813545 ydfJ 1035922 ydfJ Escherichia coli CFT073 metabolite transport protein NP_753864.1 1812178 R 199310 CDS NP_753865.2 229106380 1035923 complement(1813603..1814622) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1580; dehydrogenase 1814622 rspB 1035923 rspB Escherichia coli CFT073 dehydrogenase NP_753865.2 1813603 R 199310 CDS NP_753866.1 26247826 1035931 complement(1814634..1815881) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1581; starvation sensing protein rspA 1815881 rspA 1035931 rspA Escherichia coli CFT073 starvation sensing protein rspA NP_753866.1 1814634 R 199310 CDS NP_753867.1 26247827 1035935 complement(1816054..1816389) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1582; Escherichia coli O157:H7 ortholog: z2569; hypothetical protein 1816389 ynfA 1035935 ynfA Escherichia coli CFT073 hypothetical protein NP_753867.1 1816054 R 199310 CDS NP_753868.1 26247828 1035945 1816515..1816856 1 NC_004431.1 Escherichia coli K-12 ortholog: b1583; Escherichia coli O157:H7 ortholog: z2570; hypothetical protein 1816856 ynfB 1035945 ynfB Escherichia coli CFT073 hypothetical protein NP_753868.1 1816515 D 199310 CDS NP_753869.1 26247829 1035948 1816891..1817451 1 NC_004431.1 Escherichia coli K-12 ortholog: b1584; Escherichia coli O157:H7 ortholog: z2571; spermidine N(1)-acetyltransferase 1817451 speG 1035948 speG Escherichia coli CFT073 spermidine N(1)-acetyltransferase NP_753869.1 1816891 D 199310 CDS NP_753870.2 161486227 1035952 complement(1817454..1818164) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1585; Escherichia coli O157:H7 ortholog: z2572; hypothetical protein 1818164 ynfC 1035952 ynfC Escherichia coli CFT073 hypothetical protein NP_753870.2 1817454 R 199310 CDS NP_753871.1 26247831 1035953 1818230..1818577 1 NC_004431.1 Escherichia coli K-12 ortholog: b1586; Escherichia coli O157:H7 ortholog: z2573; hypothetical protein 1818577 ynfD 1035953 ynfD Escherichia coli CFT073 hypothetical protein NP_753871.1 1818230 D 199310 CDS NP_753872.1 26247832 1035954 1818776..1821202 1 NC_004431.1 Escherichia coli K-12 ortholog: b1587; Escherichia coli O157:H7 ortholog: z2575; dimethyl sulfoxide reductase chain ynfE 1821202 ynfE 1035954 ynfE Escherichia coli CFT073 dimethyl sulfoxide reductase chain ynfE NP_753872.1 1818776 D 199310 CDS NP_753873.1 26247833 1035955 1821260..1823686 1 NC_004431.1 Escherichia coli K-12 ortholog: b1588; Escherichia coli O157:H7 ortholog: z2576; dimethyl sulfoxide reductase chain ynfF 1823686 ynfF 1035955 ynfF Escherichia coli CFT073 dimethyl sulfoxide reductase chain ynfF NP_753873.1 1821260 D 199310 CDS NP_753874.1 26247834 1035960 1823697..1824314 1 NC_004431.1 DMSO reductase iron-sulfur subunit ynfG; Escherichia coli K-12 ortholog: b1589; Escherichia coli O157:H7 ortholog: z2577; anaerobic dimethyl sulfoxide reductase chain ynfG 1824314 ynfG 1035960 ynfG Escherichia coli CFT073 anaerobic dimethyl sulfoxide reductase chain ynfG NP_753874.1 1823697 D 199310 CDS NP_753875.1 26247835 1035967 complement(1824295..1824441) 1 NC_004431.1 hypothetical protein 1824441 1035967 c1980 Escherichia coli CFT073 hypothetical protein NP_753875.1 1824295 R 199310 CDS NP_753876.1 26247836 1035970 1824316..1825170 1 NC_004431.1 DMSO reductase anchor subunit ynfH; Escherichia coli K-12 ortholog: b1590; Escherichia coli O157:H7 ortholog: z2579; anaerobic dimethyl sulfoxide reductase chain ynfH 1825170 ynfH 1035970 ynfH Escherichia coli CFT073 anaerobic dimethyl sulfoxide reductase chain ynfH NP_753876.1 1824316 D 199310 CDS NP_753877.2 161486226 1035971 1825213..1825827 1 NC_004431.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1825827 ynfI 1035971 ynfI Escherichia coli CFT073 twin-argninine leader-binding protein DmsD NP_753877.2 1825213 D 199310 CDS NP_753878.2 161486225 1035974 1826022..1827278 1 NC_004431.1 Escherichia coli K-12 ortholog: b1592; Escherichia coli O157:H7 ortholog: z2583; voltage-gated ClC-type chloride channel ClcB 1827278 ynfJ 1035974 ynfJ Escherichia coli CFT073 voltage-gated ClC-type chloride channel ClcB NP_753878.2 1826022 D 199310 CDS NP_753879.2 161486224 1035979 complement(1827231..1827926) 1 NC_004431.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1827926 bioD 1035979 bioD Escherichia coli CFT073 dithiobiotin synthetase NP_753879.2 1827231 R 199310 CDS NP_753880.1 26247840 1035983 complement(1828051..1829271) 1 NC_004431.1 Making large colonies protein; Escherichia coli K-12 ortholog: b1594; Escherichia coli O157:H7 ortholog: z2587; Mlc protein 1829271 mlc 1035983 mlc Escherichia coli CFT073 Mlc protein NP_753880.1 1828051 R 199310 CDS NP_753881.1 26247841 1035984 complement(1829406..1830299) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1595; Escherichia coli O157:H7 ortholog: z2589; transcriptional regulator YnfL 1830299 ynfL 1035984 ynfL Escherichia coli CFT073 transcriptional regulator YnfL NP_753881.1 1829406 R 199310 CDS NP_753882.1 26247842 1035986 1830406..1831659 1 NC_004431.1 Escherichia coli K-12 ortholog: b1596; Escherichia coli O157:H7 ortholog: z2590; transport protein YnfM 1831659 ynfM 1035986 ynfM Escherichia coli CFT073 transport protein YnfM NP_753882.1 1830406 D 199310 CDS NP_753883.2 161486223 1035987 1832071..1832379 1 NC_004431.1 required for growth and survival under moderately acid conditions; acid shock protein 1832379 asr 1035987 asr Escherichia coli CFT073 acid shock protein NP_753883.2 1832071 D 199310 CDS YP_004853811.1 347357932 1035990 1832093..1832470 1 NC_004431.1 acid shock protein 1832470 1035990 c1989 Escherichia coli CFT073 acid shock protein YP_004853811.1 1832093 D 199310 CDS NP_753885.1 26247845 1036003 1832655..1833476 1 NC_004431.1 Escherichia coli K-12 ortholog: b1598; Escherichia coli O157:H7 ortholog: z2592; protease ydgD 1833476 1036003 c1990 Escherichia coli CFT073 protease ydgD NP_753885.1 1832655 D 199310 CDS NP_753886.1 26247846 1036006 complement(1833515..1833844) 1 NC_004431.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1833844 ydgE 1036006 ydgE Escherichia coli CFT073 multidrug efflux system protein MdtI NP_753886.1 1833515 R 199310 CDS NP_753887.1 26247847 1036008 complement(1833831..1834196) 1 NC_004431.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ 1834196 ydgF 1036008 ydgF Escherichia coli CFT073 multidrug efflux system protein MdtJ NP_753887.1 1833831 R 199310 CDS NP_753888.1 26247848 1036021 1834608..1835642 1 NC_004431.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 1835642 tqsA 1036021 tqsA Escherichia coli CFT073 transport protein NP_753888.1 1834608 D 199310 CDS NP_753889.1 26247849 1036023 complement(1835667..1837055) 1 NC_004431.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1837055 pntB 1036023 pntB Escherichia coli CFT073 pyridine nucleotide transhydrogenase NP_753889.1 1835667 R 199310 CDS NP_753890.1 26247850 1036024 complement(1837066..1838652) 1 NC_004431.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1838652 pntA 1036024 pntA Escherichia coli CFT073 NAD(P) transhydrogenase subunit alpha NP_753890.1 1837066 R 199310 CDS NP_753891.1 26247851 1036026 1839122..1840066 1 NC_004431.1 Escherichia coli K-12 ortholog: b1604; Escherichia coli O157:H7 ortholog: z2603; hypothetical protein 1840066 ydgH 1036026 ydgH Escherichia coli CFT073 hypothetical protein NP_753891.1 1839122 D 199310 CDS NP_753892.1 26247852 1036027 1840225..1841634 1 NC_004431.1 Escherichia coli K-12 ortholog: b1605; Escherichia coli O157:H7 ortholog: z2605; arginine/ornithine antiporter 1841634 ydgI 1036027 ydgI Escherichia coli CFT073 arginine/ornithine antiporter NP_753892.1 1840225 D 199310 CDS NP_753893.1 26247853 1036028 1841671..1842393 1 NC_004431.1 Escherichia coli K-12 ortholog: b1606; Escherichia coli O157:H7 ortholog: z2606; short chain dehydrogenase 1842393 ydgB 1036028 ydgB Escherichia coli CFT073 short chain dehydrogenase NP_753893.1 1841671 D 199310 CDS NP_753894.1 26247854 1036032 complement(1842390..1842725) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1607; Escherichia coli O157:H7 ortholog: z2608; hypothetical protein 1842725 ydgC 1036032 ydgC Escherichia coli CFT073 hypothetical protein NP_753894.1 1842390 R 199310 CDS NP_753895.1 26247855 1036033 1842794..1843573 1 NC_004431.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1843573 rstA 1036033 rstA Escherichia coli CFT073 DNA-binding transcriptional regulator RstA NP_753895.1 1842794 D 199310 CDS NP_753896.1 26247856 1036038 1843577..1844878 1 NC_004431.1 Escherichia coli K-12 ortholog: b1609; Escherichia coli O157:H7 ortholog: z2610; sensor protein RstB 1844878 rstB 1036038 rstB Escherichia coli CFT073 sensor protein RstB NP_753896.1 1843577 D 199310 CDS NP_753897.1 26247857 1036040 1844942..1845883 1 NC_004431.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1845883 tus 1036040 tus Escherichia coli CFT073 DNA replication terminus site-binding protein NP_753897.1 1844942 D 199310 CDS NP_753898.1 26247858 1036041 complement(1845880..1847283) 1 NC_004431.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1847283 fumC 1036041 fumC Escherichia coli CFT073 fumarate hydratase NP_753898.1 1845880 R 199310 CDS NP_753899.1 26247859 1036044 complement(1847426..1849072) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1612; Escherichia coli O157:H7 ortholog: z2615; fumarate hydratase class I, aerobic 1849072 fumA 1036044 fumA Escherichia coli CFT073 fumarate hydratase class I, aerobic NP_753899.1 1847426 R 199310 CDS NP_753900.1 26247860 1036047 1849271..1850446 1 NC_004431.1 Escherichia coli K-12 ortholog: b1613; Escherichia coli O157:H7 ortholog: z2616; mannose-6-phosphate isomerase 1850446 manA 1036047 manA Escherichia coli CFT073 mannose-6-phosphate isomerase NP_753900.1 1849271 D 199310 CDS NP_753901.1 26247861 1036048 1850547..1852055 1 NC_004431.1 Escherichia coli K-12 ortholog: b1614; Escherichia coli O157:H7 ortholog: z2617; hypothetical protein 1852055 ydgA 1036048 ydgA Escherichia coli CFT073 hypothetical protein NP_753901.1 1850547 D 199310 CDS NP_753902.1 26247862 1036053 complement(1852100..1853365) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1615; Escherichia coli O157:H7 ortholog: z2619; outer membrane porin protein 1853365 uidC 1036053 uidC Escherichia coli CFT073 outer membrane porin protein NP_753902.1 1852100 R 199310 CDS NP_753903.1 26247863 1036058 complement(1853404..1854777) 1 NC_004431.1 Glucuronide permease; Escherichia coli K-12 ortholog: b1616; Escherichia coli O157:H7 ortholog: z2620; glucuronide transporter 1854777 uidB 1036058 uidB Escherichia coli CFT073 glucuronide transporter NP_753903.1 1853404 R 199310 CDS NP_753904.1 26247864 1036059 complement(1854774..1856585) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1617; Escherichia coli O157:H7 ortholog: z2621; beta-D-glucuronidase 1856585 uidA 1036059 uidA Escherichia coli CFT073 beta-D-glucuronidase NP_753904.1 1854774 R 199310 CDS NP_753905.1 26247865 1036061 complement(1856975..1857565) 1 NC_004431.1 Gus operon repressor; Escherichia coli K-12 ortholog: b1618; Escherichia coli O157:H7 ortholog: z2623; uid operon repressor 1857565 uidR 1036061 uidR Escherichia coli CFT073 uid operon repressor NP_753905.1 1856975 R 199310 CDS NP_753906.1 26247866 1036064 complement(1857794..1858561) 1 NC_004431.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1858561 hdhA 1036064 hdhA Escherichia coli CFT073 7-alpha-hydroxysteroid dehydrogenase NP_753906.1 1857794 R 199310 CDS NP_753907.1 26247867 1036066 complement(1858673..1859701) 1 NC_004431.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1859701 malI 1036066 malI Escherichia coli CFT073 DNA-binding transcriptional repressor MalI NP_753907.1 1858673 R 199310 CDS NP_753908.2 161486222 1036069 1859876..1861468 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1861468 malX 1036069 malX Escherichia coli CFT073 bifunctional PTS system maltose and glucose-specific transporter subunits IICB NP_753908.2 1859876 D 199310 CDS NP_753909.1 26247869 1036071 1861478..1862650 1 NC_004431.1 Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; cystathionine beta-lyase 1862650 malY 1036071 malY Escherichia coli CFT073 cystathionine beta-lyase NP_753909.1 1861478 D 199310 CDS NP_753910.1 26247870 1036085 1862754..1863755 1 NC_004431.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1863755 add 1036085 add Escherichia coli CFT073 adenosine deaminase NP_753910.1 1862754 D 199310 CDS NP_753911.2 161486221 1036088 complement(1863791..1864831) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1624; Escherichia coli O157:H7 ortholog: z2629; oxidoreductase 1864831 ydgJ 1036088 ydgJ Escherichia coli CFT073 oxidoreductase NP_753911.2 1863791 R 199310 CDS NP_753912.1 26247872 1036093 1865472..1865687 1 NC_004431.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1865687 ydgT 1036093 ydgT Escherichia coli CFT073 oriC-binding nucleoid-associated protein NP_753912.1 1865472 D 199310 CDS NP_753913.1 26247873 1036094 1865749..1866213 1 NC_004431.1 Escherichia coli K-12 ortholog: b1626; Escherichia coli O157:H7 ortholog: z2632; hypothetical protein 1866213 ydgK 1036094 ydgK Escherichia coli CFT073 hypothetical protein NP_753913.1 1865749 D 199310 CDS NP_753914.1 26247874 1036103 1866290..1866871 1 NC_004431.1 Escherichia coli K-12 ortholog: b1627; Escherichia coli O157:H7 ortholog: z2633; Na(+)-translocating NADH-quinone reductase subunit E 1866871 1036103 c2019 Escherichia coli CFT073 Na(+)-translocating NADH-quinone reductase subunit E NP_753914.1 1866290 D 199310 CDS NP_753915.1 26247875 1036107 1866871..1867449 1 NC_004431.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1867449 1036107 c2020 Escherichia coli CFT073 electron transport complex protein RnfB NP_753915.1 1866871 D 199310 CDS NP_753916.1 26247876 1036108 1867442..1869670 1 NC_004431.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1869670 1036108 c2021 Escherichia coli CFT073 electron transport complex protein RnfC NP_753916.1 1867442 D 199310 CDS NP_753917.1 26247877 1036112 1869671..1870729 1 NC_004431.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1870729 rnfD 1036112 rnfD Escherichia coli CFT073 electron transport complex protein RnfD NP_753917.1 1869671 D 199310 CDS NP_753918.1 26247878 1036113 1870733..1871353 1 NC_004431.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1871353 1036113 c2023 Escherichia coli CFT073 electron transport complex protein RnfG NP_753918.1 1870733 D 199310 CDS NP_753919.1 26247879 1036115 1871357..1872052 1 NC_004431.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1872052 ydgQ 1036115 ydgQ Escherichia coli CFT073 electron transport complex RsxE subunit NP_753919.1 1871357 D 199310 CDS NP_753920.1 26247880 1036116 1872052..1872687 1 NC_004431.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1872687 nth 1036116 nth Escherichia coli CFT073 endonuclease III NP_753920.1 1872052 D 199310 CDS NP_753921.1 26247881 1036118 1873298..1874800 1 NC_004431.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1874800 tppB 1036118 tppB Escherichia coli CFT073 tripeptide transporter permease NP_753921.1 1873298 D 199310 CDS NP_753922.1 26247882 1036120 1874906..1875511 1 NC_004431.1 Escherichia coli K-12 ortholog: b1635; Escherichia coli O157:H7 ortholog: z2647; glutathionine S-transferase 1875511 gst 1036120 gst Escherichia coli CFT073 glutathionine S-transferase NP_753922.1 1874906 D 199310 CDS NP_753923.1 26247883 1036121 complement(1875555..1876418) 1 NC_004431.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1876418 pdxY 1036121 pdxY Escherichia coli CFT073 pyridoxamine kinase NP_753923.1 1875555 R 199310 CDS NP_753924.1 26247884 1036124 complement(1876477..1877763) 1 NC_004431.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1877763 tyrS 1036124 tyrS Escherichia coli CFT073 tyrosyl-tRNA synthetase NP_753924.1 1876477 R 199310 CDS NP_753925.1 26247885 1036125 complement(1877880..1878536) 1 NC_004431.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1878536 pdxH 1036125 pdxH Escherichia coli CFT073 pyridoxamine 5'-phosphate oxidase NP_753925.1 1877880 R 199310 CDS NP_753926.1 26247886 1036129 complement(1878595..1878924) 1 NC_004431.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1878924 ydhA 1036129 ydhA Escherichia coli CFT073 lysozyme inhibitor NP_753926.1 1878595 R 199310 CDS NP_753927.1 26247887 1036131 complement(1879022..1880131) 1 NC_004431.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1880131 anmK 1036131 anmK Escherichia coli CFT073 anhydro-N-acetylmuramic acid kinase NP_753927.1 1879022 R 199310 CDS NP_753928.1 26247888 1036133 1880405..1880872 1 NC_004431.1 Escherichia coli K-12 ortholog: b1641; Escherichia coli O157:H7 ortholog: z2655; outer membrane lipoprotein slyB 1880872 slyB 1036133 slyB Escherichia coli CFT073 outer membrane lipoprotein slyB NP_753928.1 1880405 D 199310 CDS NP_753929.2 161486220 1036136 complement(1880919..1881353) 1 NC_004431.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1881353 slyA 1036136 slyA Escherichia coli CFT073 transcriptional regulator SlyA NP_753929.2 1880919 R 199310 CDS NP_753930.1 26247890 1036138 1881554..1881790 1 NC_004431.1 Escherichia coli K-12 ortholog: b1643; Escherichia coli O157:H7 ortholog: z2658; hypothetical protein 1881790 ydhI 1036138 ydhI Escherichia coli CFT073 hypothetical protein NP_753930.1 1881554 D 199310 CDS NP_753931.1 26247891 1036140 1881751..1882650 1 NC_004431.1 Escherichia coli K-12 ortholog: b1644; Escherichia coli O157:H7 ortholog: z2659; hypothetical protein 1882650 ydhJ 1036140 ydhJ Escherichia coli CFT073 hypothetical protein NP_753931.1 1881751 D 199310 CDS NP_753932.1 26247892 1036142 1882650..1884662 1 NC_004431.1 Escherichia coli K-12 ortholog: b1645; Escherichia coli O157:H7 ortholog: z2660; hypothetical protein 1884662 ydhK 1036142 ydhK Escherichia coli CFT073 hypothetical protein NP_753932.1 1882650 D 199310 CDS NP_753933.1 26247893 1036143 complement(1884663..1885235) 1 NC_004431.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1885235 sodC 1036143 sodC Escherichia coli CFT073 superoxide dismutase NP_753933.1 1884663 R 199310 CDS NP_753934.1 26247894 1036144 complement(1885265..1886161) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1647; Escherichia coli O157:H7 ortholog: z2664; oxidoreductase ydhF 1886161 ydhF 1036144 ydhF Escherichia coli CFT073 oxidoreductase ydhF NP_753934.1 1885265 R 199310 CDS NP_753935.1 26247895 1036146 complement(1886210..1886587) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1648; Escherichia coli O157:H7 ortholog: z2665; hypothetical protein 1886587 ydhL 1036146 ydhL Escherichia coli CFT073 hypothetical protein NP_753935.1 1886210 R 199310 CDS NP_753936.1 26247896 1036148 1886218..1886340 1 NC_004431.1 hypothetical protein 1886340 1036148 c2041 Escherichia coli CFT073 hypothetical protein NP_753936.1 1886218 D 199310 CDS NP_753937.1 26247897 1036152 1886552..1887151 1 NC_004431.1 Escherichia coli K-12 ortholog: b1649; Escherichia coli O157:H7 ortholog: z2666; transcriptional regulator YdhM 1887151 ydhM 1036152 ydhM Escherichia coli CFT073 transcriptional regulator YdhM NP_753937.1 1886552 D 199310 CDS NP_753938.1 26247898 1036153 1887188..1888285 1 NC_004431.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1888285 nemA 1036153 nemA Escherichia coli CFT073 N-ethylmaleimide reductase NP_753938.1 1887188 D 199310 CDS NP_753939.1 26247899 1036158 1888366..1888773 1 NC_004431.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1888773 gloA 1036158 gloA Escherichia coli CFT073 glyoxalase I NP_753939.1 1888366 D 199310 CDS NP_753940.1 26247900 1036159 1888876..1889523 1 NC_004431.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1889523 rnt 1036159 rnt Escherichia coli CFT073 ribonuclease T NP_753940.1 1888876 D 199310 CDS NP_753941.1 26247901 1036162 complement(1889585..1889728) 1 NC_004431.1 hypothetical protein 1889728 1036162 c2046 Escherichia coli CFT073 hypothetical protein NP_753941.1 1889585 R 199310 CDS NP_753942.1 26247902 1036172 1889616..1889759 1 NC_004431.1 Residues 1 to 37 of 47 are 94.59 pct identical to residues 1 to 37 of 1538 from GenPept.129 : >gb|AAG56642.1|AE005388_7 (AE005388) member of ATP-dependent helicase superfamily II [Escherichia coli O157:H7 EDL933]; hypothetical protein 1889759 1036172 c2047 Escherichia coli CFT073 hypothetical protein NP_753942.1 1889616 D 199310 CDS NP_753943.1 26247903 1036173 complement(1889895..1890242) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1654; Escherichia coli O157:H7 ortholog: z2676; hypothetical protein 1890242 ydhD 1036173 ydhD Escherichia coli CFT073 hypothetical protein NP_753943.1 1889895 R 199310 CDS NP_753944.1 26247904 1036176 1890577..1891404 1 NC_004431.1 Escherichia coli K-12 ortholog: b1655; Escherichia coli O157:H7 ortholog: z2677; hypothetical protein 1891404 ydhO 1036176 ydhO Escherichia coli CFT073 hypothetical protein NP_753944.1 1890577 D 199310 CDS NP_753945.1 26247905 1036179 1891532..1892113 1 NC_004431.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1892113 sodB 1036179 sodB Escherichia coli CFT073 superoxide dismutase NP_753945.1 1891532 D 199310 CDS NP_753946.1 26247906 1036180 complement(1892259..1893428) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1657; Escherichia coli O157:H7 ortholog: z2679; transport protein YdhP 1893428 ydhP 1036180 ydhP Escherichia coli CFT073 transport protein YdhP NP_753946.1 1892259 R 199310 CDS NP_753947.1 26247907 1036187 1893982..1895007 1 NC_004431.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1895007 purR 1036187 purR Escherichia coli CFT073 DNA-binding transcriptional repressor PurR NP_753947.1 1893982 D 199310 CDS NP_753948.1 26247908 1036190 complement(1895004..1895936) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1659; Escherichia coli O157:H7 ortholog: z2682; DNA-binding transcriptional regulator 1895936 ydhB 1036190 ydhB Escherichia coli CFT073 DNA-binding transcriptional regulator NP_753948.1 1895004 R 199310 CDS NP_753949.1 26247909 1036194 1896049..1897260 1 NC_004431.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1897260 ydhC 1036194 ydhC Escherichia coli CFT073 inner membrane transport protein YdhC NP_753949.1 1896049 D 199310 CDS NP_753950.1 26247910 1036202 1897551..1898699 1 NC_004431.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1898699 cfa 1036202 cfa Escherichia coli CFT073 cyclopropane fatty acyl phospholipid synthase NP_753950.1 1897551 D 199310 CDS NP_753951.1 26247911 1036204 complement(1898739..1899380) 1 NC_004431.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1899380 ribE 1036204 ribE Escherichia coli CFT073 riboflavin synthase subunit alpha NP_753951.1 1898739 R 199310 CDS NP_753952.1 26247912 1036205 1899595..1900968 1 NC_004431.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1900968 ydhE 1036205 ydhE Escherichia coli CFT073 multidrug efflux protein NP_753952.1 1899595 D 199310 CDS NP_753953.1 26247913 1036207 complement(1901009..1902265) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1664; Escherichia coli O157:H7 ortholog: z2691; hypothetical protein 1902265 ydhQ 1036207 ydhQ Escherichia coli CFT073 hypothetical protein NP_753953.1 1901009 R 199310 CDS NP_753954.1 26247914 1036218 1902839..1903144 1 NC_004431.1 Escherichia coli K-12 ortholog: b1667; Escherichia coli O157:H7 ortholog: z2694; hypothetical protein 1903144 1036218 c2059 Escherichia coli CFT073 hypothetical protein NP_753954.1 1902839 D 199310 CDS NP_753955.1 26247915 1036219 1903270..1904880 1 NC_004431.1 Escherichia coli K-12 ortholog: b1668; Escherichia coli O157:H7 ortholog: z2695; hypothetical protein 1904880 ydhS 1036219 ydhS Escherichia coli CFT073 hypothetical protein NP_753955.1 1903270 D 199310 CDS NP_753956.1 26247916 1036221 complement(1904867..1904992) 1 NC_004431.1 hypothetical protein 1904992 1036221 c2061 Escherichia coli CFT073 hypothetical protein NP_753956.1 1904867 R 199310 CDS NP_753957.1 26247917 1036223 complement(1904886..1905698) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1669; Escherichia coli O157:H7 ortholog: z2696; hypothetical protein 1905698 ydhT 1036223 ydhT Escherichia coli CFT073 hypothetical protein NP_753957.1 1904886 R 199310 CDS NP_753958.1 26247918 1036226 1905087..1905833 1 NC_004431.1 hypothetical protein 1905833 1036226 c2063 Escherichia coli CFT073 hypothetical protein NP_753958.1 1905087 D 199310 CDS NP_753959.1 26247919 1036229 complement(1905702..1906487) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1670; Escherichia coli O157:H7 ortholog: z2697; PhsC protein 1906487 ydhU 1036229 ydhU Escherichia coli CFT073 PhsC protein NP_753959.1 1905702 R 199310 CDS NP_753960.1 26247920 1036236 complement(1906484..1907203) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1671; Escherichia coli O157:H7 ortholog: z2698; ferredoxin-like protein ydhX 1907203 1036236 c2065 Escherichia coli CFT073 ferredoxin-like protein ydhX NP_753960.1 1906484 R 199310 CDS NP_753961.1 26247921 1036238 complement(1907216..1907863) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1672; Escherichia coli O157:H7 ortholog: z2700; hypothetical protein 1907863 ydhW 1036238 ydhW Escherichia coli CFT073 hypothetical protein NP_753961.1 1907216 R 199310 CDS NP_753962.2 161486219 1036243 complement(1907867..1909969) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1673; Escherichia coli O157:H7 ortholog: z2701; oxidoreductase 1909969 ydhV 1036243 ydhV Escherichia coli CFT073 oxidoreductase NP_753962.2 1907867 R 199310 CDS NP_753963.1 26247923 1036249 complement(1909990..1910616) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1674; Escherichia coli O157:H7 ortholog: z2702; hypothetical protein 1910616 1036249 c2068 Escherichia coli CFT073 hypothetical protein NP_753963.1 1909990 R 199310 CDS NP_753964.1 26247924 1036251 complement(1911072..1911281) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1675; Escherichia coli O157:H7 ortholog: z2703; hypothetical protein 1911281 ydhZ 1036251 ydhZ Escherichia coli CFT073 hypothetical protein NP_753964.1 1911072 R 199310 CDS NP_753965.1 26247925 1036254 1911393..1911521 1 NC_004431.1 hypothetical protein 1911521 1036254 c2070 Escherichia coli CFT073 hypothetical protein NP_753965.1 1911393 D 199310 CDS NP_753966.1 26247926 1036261 1911623..1913251 1 NC_004431.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1913251 pykF 1036261 pykF Escherichia coli CFT073 pyruvate kinase NP_753966.1 1911623 D 199310 CDS NP_753967.1 26247927 1036271 1913562..1913798 1 NC_004431.1 Murein-lipoprotein; Escherichia coli K-12 ortholog: b1677; Escherichia coli O157:H7 ortholog: z2705; major outer membrane lipoprotein 1913798 lpp 1036271 lpp Escherichia coli CFT073 major outer membrane lipoprotein NP_753967.1 1913562 D 199310 CDS NP_753968.1 26247928 1036272 complement(1913861..1914865) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1678; Escherichia coli O157:H7 ortholog: z2706; hypothetical protein 1914865 ynhG 1036272 ynhG Escherichia coli CFT073 hypothetical protein NP_753968.1 1913861 R 199310 CDS NP_753969.1 26247929 1036273 complement(1915014..1915430) 1 NC_004431.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1915430 ynhA 1036273 ynhA Escherichia coli CFT073 cysteine desufuration protein SufE NP_753969.1 1915014 R 199310 CDS NP_753970.1 26247930 1036285 complement(1915443..1916663) 1 NC_004431.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1916663 1036285 c2075 Escherichia coli CFT073 bifunctional cysteine desulfurase/selenocysteine lyase NP_753970.1 1915443 R 199310 CDS NP_753971.1 26247931 1036312 complement(1916660..1917931) 1 NC_004431.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1917931 ynhC 1036312 ynhC Escherichia coli CFT073 cysteine desulfurase activator complex subunit SufD NP_753971.1 1916660 R 199310 CDS NP_753972.1 26247932 1036316 complement(1917906..1918652) 1 NC_004431.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase component 1918652 sufC 1036316 sufC Escherichia coli CFT073 cysteine desulfurase ATPase component NP_753972.1 1917906 R 199310 CDS NP_753973.1 26247933 1036318 complement(1918662..1920188) 1 NC_004431.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1920188 ynhE 1036318 ynhE Escherichia coli CFT073 cysteine desulfurase activator complex subunit SufB NP_753973.1 1918662 R 199310 CDS NP_753974.1 26247934 1036331 complement(1920158..1920526) 1 NC_004431.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1920526 sufA 1036331 sufA Escherichia coli CFT073 iron-sulfur cluster assembly scaffold protein NP_753974.1 1920158 R 199310 CDS NP_753975.1 26247935 1036340 complement(1921075..1921344) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1685; Escherichia coli O157:H7 ortholog: z2713; hypothetical protein 1921344 ydiH 1036340 ydiH Escherichia coli CFT073 hypothetical protein NP_753975.1 1921075 R 199310 CDS NP_753976.1 26247936 1036342 complement(1921363..1921773) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1686; Escherichia coli O157:H7 ortholog: z2714; hypothetical protein 1921773 ydiI 1036342 ydiI Escherichia coli CFT073 hypothetical protein NP_753976.1 1921363 R 199310 CDS NP_753977.1 26247937 1036348 complement(1921770..1924826) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1687; Escherichia coli O157:H7 ortholog: z2715; hypothetical protein 1924826 ydiJ 1036348 ydiJ Escherichia coli CFT073 hypothetical protein NP_753977.1 1921770 R 199310 CDS NP_753978.1 26247938 1036354 1925040..1926152 1 NC_004431.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1926152 ydiK 1036354 ydiK Escherichia coli CFT073 inner membrane protein NP_753978.1 1925040 D 199310 CDS NP_753979.1 26247939 1036357 1926554..1926937 1 NC_004431.1 Escherichia coli K-12 ortholog: b1689; Escherichia coli O157:H7 ortholog: z2717; hypothetical protein 1926937 ydiL 1036357 ydiL Escherichia coli CFT073 hypothetical protein NP_753979.1 1926554 D 199310 CDS NP_753980.1 26247940 1036359 1927037..1928251 1 NC_004431.1 Escherichia coli K-12 ortholog: b1690; Escherichia coli O157:H7 ortholog: z2718; transport protein YdiM 1928251 ydiM 1036359 ydiM Escherichia coli CFT073 transport protein YdiM NP_753980.1 1927037 D 199310 CDS NP_753981.1 26247941 1036365 1928472..1929743 1 NC_004431.1 Escherichia coli K-12 ortholog: b1691; Escherichia coli O157:H7 ortholog: z2719; transport protein YdiN 1929743 ydiN 1036365 ydiN Escherichia coli CFT073 transport protein YdiN NP_753981.1 1928472 D 199310 CDS NP_753982.1 26247942 1036366 1929755..1930621 1 NC_004431.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1930621 aroE 1036366 aroE Escherichia coli CFT073 quinate/shikimate dehydrogenase NP_753982.1 1929755 D 199310 CDS NP_753983.1 26247943 1036367 1930652..1931410 1 NC_004431.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1931410 aroD 1036367 aroD Escherichia coli CFT073 3-dehydroquinate dehydratase NP_753983.1 1930652 D 199310 CDS NP_753984.1 26247944 1036370 1931556..1933151 1 NC_004431.1 Escherichia coli K-12 ortholog: b1694; Escherichia coli O157:H7 ortholog: z2722; hypothetical protein 1933151 ydiF 1036370 ydiF Escherichia coli CFT073 hypothetical protein NP_753984.1 1931556 D 199310 CDS NP_753985.2 161486218 1036372 1933165..1934316 1 NC_004431.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1934316 ydiO 1036372 ydiO Escherichia coli CFT073 acyl-CoA dehydrogenase NP_753985.2 1933165 D 199310 CDS NP_753986.1 26247946 1036377 complement(1934359..1935270) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1696; Escherichia coli O157:H7 ortholog: z2724; transcriptional regulator YdiP 1935270 ydiP 1036377 ydiP Escherichia coli CFT073 transcriptional regulator YdiP NP_753986.1 1934359 R 199310 CDS NP_753987.1 26247947 1036386 complement(1935373..1935549) 1 NC_004431.1 hypothetical protein 1935549 1036386 c2092 Escherichia coli CFT073 hypothetical protein NP_753987.1 1935373 R 199310 CDS NP_753988.2 161486217 1036390 1935586..1936350 1 NC_004431.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1936350 ydiQ 1036390 ydiQ Escherichia coli CFT073 electron transfer flavoprotein YdiQ NP_753988.2 1935586 D 199310 CDS NP_753989.1 26247949 1036391 1936370..1937308 1 NC_004431.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1937308 ydiR 1036391 ydiR Escherichia coli CFT073 electron transfer flavoprotein subunit YdiR NP_753989.1 1936370 D 199310 CDS NP_753990.1 26247950 1036392 1937363..1938652 1 NC_004431.1 Escherichia coli K-12 ortholog: b1699; Escherichia coli O157:H7 ortholog: z2728; hypothetical protein 1938652 ydiS 1036392 ydiS Escherichia coli CFT073 hypothetical protein NP_753990.1 1937363 D 199310 CDS NP_753991.1 26247951 1036395 1938649..1938942 1 NC_004431.1 Escherichia coli K-12 ortholog: b1700; Escherichia coli O157:H7 ortholog: z2729; ferredoxin-like protein ydiT 1938942 ydiT 1036395 ydiT Escherichia coli CFT073 ferredoxin-like protein ydiT NP_753991.1 1938649 D 199310 CDS NP_753992.1 26247952 1036396 1938945..1940645 1 NC_004431.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1940645 ydiD 1036396 ydiD Escherichia coli CFT073 short chain acyl-CoA synthetase NP_753992.1 1938945 D 199310 CDS NP_753993.1 26247953 1036397 complement(1940702..1943080) 1 NC_004431.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1943080 ppsA 1036397 ppsA Escherichia coli CFT073 phosphoenolpyruvate synthase NP_753993.1 1940702 R 199310 CDS NP_753994.1 26247954 1036398 1943413..1944246 1 NC_004431.1 Escherichia coli K-12 ortholog: b1703; Escherichia coli O157:H7 ortholog: z2732; hypothetical protein 1944246 ydiA 1036398 ydiA Escherichia coli CFT073 hypothetical protein NP_753994.1 1943413 D 199310 CDS NP_753995.1 26247955 1036404 1944403..1945449 1 NC_004431.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1945449 aroH 1036404 aroH Escherichia coli CFT073 phospho-2-dehydro-3-deoxyheptonate aldolase NP_753995.1 1944403 D 199310 CDS NP_753996.1 26247956 1036409 1945554..1945772 1 NC_004431.1 Escherichia coli K-12 ortholog: b1705; Escherichia coli O157:H7 ortholog: z2734; hypothetical protein 1945772 ydiE 1036409 ydiE Escherichia coli CFT073 hypothetical protein NP_753996.1 1945554 D 199310 CDS NP_753997.1 26247957 1036411 complement(1945776..1947212) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1706; Escherichia coli O157:H7 ortholog: z2735; hypothetical protein 1947212 ydiU 1036411 ydiU Escherichia coli CFT073 hypothetical protein NP_753997.1 1945776 R 199310 CDS NP_753998.1 26247958 1036412 complement(1947275..1947988) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1707; Escherichia coli O157:H7 ortholog: z2736; hypothetical protein 1947988 ydiV 1036412 ydiV Escherichia coli CFT073 hypothetical protein NP_753998.1 1947275 R 199310 CDS NP_753999.1 26247959 1036414 complement(1948235..1948699) 1 NC_004431.1 ORF-17; Escherichia coli K-12 ortholog: b1708; Escherichia coli O157:H7 ortholog: z2737; lipoprotein NlpC 1948699 nlpC 1036414 nlpC Escherichia coli CFT073 lipoprotein NlpC NP_753999.1 1948235 R 199310 CDS NP_754000.1 26247960 1036415 complement(1948777..1949526) 1 NC_004431.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1949526 btuD 1036415 btuD Escherichia coli CFT073 vitamin B12-transporter ATPase NP_754000.1 1948777 R 199310 CDS NP_754001.1 26247961 1036421 complement(1949526..1950077) 1 NC_004431.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 1950077 btuE 1036421 btuE Escherichia coli CFT073 glutathione peroxidase NP_754001.1 1949526 R 199310 CDS NP_754002.1 26247962 1036429 complement(1950139..1951119) 1 NC_004431.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1951119 btuC 1036429 btuC Escherichia coli CFT073 vtamin B12-transporter permease NP_754002.1 1950139 R 199310 CDS NP_754003.1 26247963 1036431 complement(1951016..1951144) 1 NC_004431.1 hypothetical protein 1951144 1036431 c2108 Escherichia coli CFT073 hypothetical protein NP_754003.1 1951016 R 199310 CDS NP_754004.1 26247964 1036432 complement(1951220..1951519) 1 NC_004431.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1951519 ihfA 1036432 ihfA Escherichia coli CFT073 integration host factor subunit alpha NP_754004.1 1951220 R 199310 CDS NP_754005.2 161486216 1036438 complement(1953927..1954910) 1 NC_004431.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1954910 pheS 1036438 pheS Escherichia coli CFT073 phenylalanyl-tRNA synthetase subunit alpha NP_754005.2 1953927 R 199310 CDS NP_754007.1 26247967 1036447 complement(1955361..1955717) 1 NC_004431.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1955717 rplT 1036447 rplT Escherichia coli CFT073 50S ribosomal protein L20 NP_754007.1 1955361 R 199310 CDS NP_754008.1 26247968 1036451 1955839..1956450 1 NC_004431.1 hypothetical protein 1956450 1036451 c2114 Escherichia coli CFT073 hypothetical protein NP_754008.1 1955839 D 199310 CDS NP_754009.1 26247969 1036455 complement(1956064..1956498) 1 NC_004431.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1956498 infC 1036455 infC Escherichia coli CFT073 translation initiation factor IF-3 NP_754009.1 1956064 R 199310 CDS NP_754010.1 26247970 1036459 complement(1956610..1958538) 1 NC_004431.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1958538 thrS 1036459 thrS Escherichia coli CFT073 threonyl-tRNA synthetase NP_754010.1 1956610 R 199310 CDS NP_754011.1 26247971 1036467 1959224..1959589 1 NC_004431.1 Residues 12 to 97 of 121 are 88.37 pct identical to residues 66 to 151 of 157 from MG1655 : b1720; hypothetical protein 1959589 1036467 c2117 Escherichia coli CFT073 hypothetical protein NP_754011.1 1959224 D 199310 CDS NP_754012.1 26247972 1036473 1959607..1959918 1 NC_004431.1 Residues 1 to 83 of 103 are 93.97 pct identical to residues 22 to 104 of 471 from MG1655 : b1721; hypothetical protein 1959918 1036473 c2118 Escherichia coli CFT073 hypothetical protein NP_754012.1 1959607 D 199310 CDS NP_754013.1 26247973 1036480 1959899..1960090 1 NC_004431.1 Residues 2 to 63 of 63 are 93.54 pct identical to residues 571 to 632 of 632 from GenPept.129 : >gb|AAG56707.1|AE005395_3 (AE005395) Z2749 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 1960090 1036480 c2119 Escherichia coli CFT073 hypothetical protein NP_754013.1 1959899 D 199310 CDS NP_754014.1 26247974 1036495 complement(1960421..1961179) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1722; Escherichia coli O157:H7 ortholog: z2751; hypothetical protein 1961179 ydiY 1036495 ydiY Escherichia coli CFT073 hypothetical protein NP_754014.1 1960421 R 199310 CDS NP_754015.1 26247975 1036501 1961463..1962395 1 NC_004431.1 Escherichia coli K-12 ortholog: b1723; Escherichia coli O157:H7 ortholog: z2752; 6-phosphofructokinase 1962395 pfkB 1036501 pfkB Escherichia coli CFT073 6-phosphofructokinase NP_754015.1 1961463 D 199310 CDS NP_754016.1 26247976 1036510 complement(1962424..1962801) 1 NC_004431.1 hypothetical protein 1962801 1036510 c2122 Escherichia coli CFT073 hypothetical protein NP_754016.1 1962424 R 199310 CDS NP_754017.1 26247977 1036522 1962496..1962786 1 NC_004431.1 Escherichia coli K-12 ortholog: b1724; Escherichia coli O157:H7 ortholog: z2753; hypothetical protein 1962786 ydiZ 1036522 ydiZ Escherichia coli CFT073 hypothetical protein NP_754017.1 1962496 D 199310 CDS NP_754018.1 26247978 1036523 1962892..1963752 1 NC_004431.1 Escherichia coli K-12 ortholog: b1725; Escherichia coli O157:H7 ortholog: z2754; hypothetical protein 1963752 yniA 1036523 yniA Escherichia coli CFT073 hypothetical protein NP_754018.1 1962892 D 199310 CDS NP_754019.1 26247979 1036524 complement(1963793..1964329) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1726; Escherichia coli O157:H7 ortholog: z2755; hypothetical protein 1964329 yniB 1036524 yniB Escherichia coli CFT073 hypothetical protein NP_754019.1 1963793 R 199310 CDS NP_754020.1 26247980 1036526 1964476..1965144 1 NC_004431.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1965144 yniC 1036526 yniC Escherichia coli CFT073 2-deoxyglucose-6-phosphatase NP_754020.1 1964476 D 199310 CDS NP_754021.2 161486215 1036530 1965308..1965898 1 NC_004431.1 Escherichia coli K-12 ortholog: b1728; Escherichia coli O157:H7 ortholog: z2757; hypothetical protein 1965898 ydjM 1036530 ydjM Escherichia coli CFT073 hypothetical protein NP_754021.2 1965308 D 199310 CDS NP_754022.1 26247982 1036532 1966031..1967422 1 NC_004431.1 Escherichia coli K-12 ortholog: b1729; Escherichia coli O157:H7 ortholog: z2758; symporter ydjN 1967422 ydjN 1036532 ydjN Escherichia coli CFT073 symporter ydjN NP_754022.1 1966031 D 199310 CDS NP_754023.1 26247983 1036535 complement(1967469..1967732) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1731; Escherichia coli O157:H7 ortholog: z2760; cell division modulator 1967732 1036535 c2129 Escherichia coli CFT073 cell division modulator NP_754023.1 1967469 R 199310 CDS NP_754024.1 26247984 1036536 complement(1967898..1968056) 1 NC_004431.1 hypothetical protein 1968056 1036536 c2130 Escherichia coli CFT073 hypothetical protein NP_754024.1 1967898 R 199310 CDS NP_754025.1 26247985 1036537 1967915..1970176 1 NC_004431.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1970176 katE 1036537 katE Escherichia coli CFT073 hydroperoxidase II NP_754025.1 1967915 D 199310 CDS NP_754026.1 26247986 1036539 complement(1970223..1970981) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1733; Escherichia coli O157:H7 ortholog: z2763; hypothetical protein 1970981 ydjC 1036539 ydjC Escherichia coli CFT073 hypothetical protein NP_754026.1 1970223 R 199310 CDS NP_754027.1 26247987 1036543 complement(1970994..1972400) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1734; Escherichia coli O157:H7 ortholog: z2764; 6-phospho-beta-glucosidase 1972400 celF 1036543 celF Escherichia coli CFT073 6-phospho-beta-glucosidase NP_754027.1 1970994 R 199310 CDS NP_754028.1 26247988 1036544 complement(1972449..1973291) 1 NC_004431.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1973291 celD 1036544 celD Escherichia coli CFT073 DNA-binding transcriptional regulator ChbR NP_754028.1 1972449 R 199310 CDS NP_754029.1 26247989 1036547 complement(1973299..1973649) 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1973649 celC 1036547 celC Escherichia coli CFT073 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA NP_754029.1 1973299 R 199310 CDS NP_754030.1 26247990 1036548 complement(1973700..1975058) 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1975058 celB 1036548 celB Escherichia coli CFT073 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC NP_754030.1 1973700 R 199310 CDS NP_754031.1 26247991 1036550 complement(1975143..1975463) 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1975463 celA 1036550 celA Escherichia coli CFT073 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB NP_754031.1 1975143 R 199310 CDS NP_754032.1 26247992 1036554 complement(1975763..1976101) 1 NC_004431.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1976101 osmE 1036554 osmE Escherichia coli CFT073 DNA-binding transcriptional activator OsmE NP_754032.1 1975763 R 199310 CDS NP_754033.1 26247993 1036556 1976303..1977130 1 NC_004431.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1977130 nadE 1036556 nadE Escherichia coli CFT073 NAD synthetase NP_754033.1 1976303 D 199310 CDS NP_754034.1 26247994 1036559 1977360..1978247 1 NC_004431.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1978247 ydjQ 1036559 ydjQ Escherichia coli CFT073 nucleotide excision repair endonuclease NP_754034.1 1977360 D 199310 CDS NP_754035.1 26247995 1036563 complement(1978207..1978845) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1742; Escherichia coli O157:H7 ortholog: z2774; hypothetical protein 1978845 ydjR 1036563 ydjR Escherichia coli CFT073 hypothetical protein NP_754035.1 1978207 R 199310 CDS NP_754036.1 26247996 1036566 1978973..1979461 1 NC_004431.1 hypothetical protein 1979461 1036566 c2142 Escherichia coli CFT073 hypothetical protein NP_754036.1 1978973 D 199310 CDS NP_754037.1 26247997 1036567 complement(1978985..1979470) 1 NC_004431.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein 1979470 spy 1036567 spy Escherichia coli CFT073 periplasmic protein NP_754037.1 1978985 R 199310 CDS NP_754038.1 26247998 1036569 complement(1979800..1980768) 1 NC_004431.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1980768 ydjS 1036569 ydjS Escherichia coli CFT073 succinylglutamate desuccinylase NP_754038.1 1979800 R 199310 CDS NP_754039.1 26247999 1036570 complement(1980761..1982104) 1 NC_004431.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1982104 1036570 c2145 Escherichia coli CFT073 succinylarginine dihydrolase NP_754039.1 1980761 R 199310 CDS NP_754040.1 26248000 1036571 complement(1982101..1983579) 1 NC_004431.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1983579 astD 1036571 astD Escherichia coli CFT073 succinylglutamic semialdehyde dehydrogenase NP_754040.1 1982101 R 199310 CDS NP_754041.1 26248001 1036572 complement(1983663..1984610) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1747; Escherichia coli O157:H7 ortholog: z2779; arginine succinyltransferase 1984610 1036572 c2147 Escherichia coli CFT073 arginine succinyltransferase NP_754041.1 1983663 R 199310 CDS NP_754042.1 26248002 1036573 complement(1984607..1985827) 1 NC_004431.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1985827 argD 1036573 argD Escherichia coli CFT073 bifunctional succinylornithine transaminase/acetylornithine transaminase NP_754042.1 1984607 R 199310 CDS NP_754043.1 26248003 1036576 1986090..1986260 1 NC_004431.1 hypothetical protein 1986260 1036576 c2149 Escherichia coli CFT073 hypothetical protein NP_754043.1 1986090 D 199310 CDS NP_754044.2 161486214 1036577 1986273..1987079 1 NC_004431.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1987079 xthA 1036577 xthA Escherichia coli CFT073 exonuclease III NP_754044.2 1986273 D 199310 CDS NP_754045.1 26248005 1036579 1987198..1987956 1 NC_004431.1 Escherichia coli K-12 ortholog: b1750; Escherichia coli O157:H7 ortholog: z2782; hypothetical protein 1987956 ydjX 1036579 ydjX Escherichia coli CFT073 hypothetical protein NP_754045.1 1987198 D 199310 CDS NP_754046.1 26248006 1036581 1987799..1988638 1 NC_004431.1 Escherichia coli K-12 ortholog: b1751; Escherichia coli O157:H7 ortholog: z2783; hypothetical protein 1988638 ydjY 1036581 ydjY Escherichia coli CFT073 hypothetical protein NP_754046.1 1987799 D 199310 CDS NP_754047.1 26248007 1036584 1988652..1989359 1 NC_004431.1 Escherichia coli K-12 ortholog: b1752; Escherichia coli O157:H7 ortholog: z2784; hypothetical protein 1989359 ydjZ 1036584 ydjZ Escherichia coli CFT073 hypothetical protein NP_754047.1 1988652 D 199310 CDS NP_754048.1 26248008 1036585 1989359..1989907 1 NC_004431.1 Escherichia coli K-12 ortholog: b1753; Escherichia coli O157:H7 ortholog: z2785; hypothetical protein 1989907 ynjA 1036585 ynjA Escherichia coli CFT073 hypothetical protein NP_754048.1 1989359 D 199310 CDS NP_754049.1 26248009 1036586 1989917..1991083 1 NC_004431.1 Escherichia coli K-12 ortholog: b1754; Escherichia coli O157:H7 ortholog: z2786; ABC transporter solute-binding protein 1991083 1036586 c2155 Escherichia coli CFT073 ABC transporter solute-binding protein NP_754049.1 1989917 D 199310 CDS NP_754050.1 26248010 1036588 1991032..1992591 1 NC_004431.1 Escherichia coli K-12 ortholog: b1755; Escherichia coli O157:H7 ortholog: z2787; ABC transporter permease 1992591 ynjC 1036588 ynjC Escherichia coli CFT073 ABC transporter permease NP_754050.1 1991032 D 199310 CDS NP_754051.1 26248011 1036590 1992558..1993244 1 NC_004431.1 Escherichia coli K-12 ortholog: b1756; Escherichia coli O157:H7 ortholog: z2788; ABC transporter ATP-binding protein 1993244 ynjD 1036590 ynjD Escherichia coli CFT073 ABC transporter ATP-binding protein NP_754051.1 1992558 D 199310 CDS NP_754052.1 26248012 1036591 1993296..1994618 1 NC_004431.1 Escherichia coli K-12 ortholog: b1757; Escherichia coli O157:H7 ortholog: z2789; thiosulfate sulfurtransferase ynjE 1994618 1036591 c2158 Escherichia coli CFT073 thiosulfate sulfurtransferase ynjE NP_754052.1 1993296 D 199310 CDS NP_754053.1 26248013 1036592 complement(1994627..1995253) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1758; Escherichia coli O157:H7 ortholog: z2790; hypothetical protein 1995253 ynjF 1036592 ynjF Escherichia coli CFT073 hypothetical protein NP_754053.1 1994627 R 199310 CDS NP_754054.1 26248014 1036593 1995334..1995741 1 NC_004431.1 Escherichia coli K-12 ortholog: b1759; Escherichia coli O157:H7 ortholog: z2791; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1995741 1036593 c2160 Escherichia coli CFT073 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase NP_754054.1 1995334 D 199310 CDS NP_754055.1 26248015 1036595 complement(1995707..1995979) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1760; Escherichia coli O157:H7 ortholog: z2792; hypothetical protein 1995979 ynjH 1036595 ynjH Escherichia coli CFT073 hypothetical protein NP_754055.1 1995707 R 199310 CDS NP_754056.1 26248016 1036597 1996215..1997558 1 NC_004431.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1997558 gdhA 1036597 gdhA Escherichia coli CFT073 glutamate dehydrogenase NP_754056.1 1996215 D 199310 CDS NP_754057.1 26248017 1036598 complement(1997614..1999557) 1 NC_004431.1 Residues 319 to 628 of 647 are 30.22 pct identical to residues 22 to 328 of 331 from GenPept.129 : >gb|AAL19605.1| (AE008726) TPR repeat protein [Salmonella typhimurium LT2]; hypothetical protein 1999557 1036598 c2163 Escherichia coli CFT073 hypothetical protein NP_754057.1 1997614 R 199310 CDS NP_754058.1 26248018 1036600 complement(1999554..2001254) 1 NC_004431.1 Hsc62; Escherichia coli K-12 ortholog: b0650; Escherichia coli O157:H7 ortholog: z0800; chaperone protein hscC 2001254 ybeW 1036600 ybeW Escherichia coli CFT073 chaperone protein hscC NP_754058.1 1999554 R 199310 CDS NP_754059.1 26248019 1036601 complement(2001324..2002124) 1 NC_004431.1 hypothetical protein 2002124 1036601 c2165 Escherichia coli CFT073 hypothetical protein NP_754059.1 2001324 R 199310 CDS NP_754060.1 26248020 1036602 complement(2002243..2004246) 1 NC_004431.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2004246 topB 1036602 topB Escherichia coli CFT073 DNA topoisomerase III NP_754060.1 2002243 R 199310 CDS NP_754061.1 26248021 1036603 complement(2004194..2005243) 1 NC_004431.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2005243 selD 1036603 selD Escherichia coli CFT073 selenophosphate synthetase NP_754061.1 2004194 R 199310 CDS NP_754062.2 229106379 1036604 complement(2005354..2005905) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1765; Escherichia coli O157:H7 ortholog: z2798; hypothetical protein 2005905 ydjA 1036604 ydjA Escherichia coli CFT073 hypothetical protein NP_754062.2 2005354 R 199310 CDS NP_754063.1 26248023 1036605 2005959..2006123 1 NC_004431.1 hypothetical protein 2006123 1036605 c2169 Escherichia coli CFT073 hypothetical protein NP_754063.1 2005959 D 199310 CDS NP_754064.1 26248024 1036606 2006066..2007922 1 NC_004431.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2007922 sppA 1036606 sppA Escherichia coli CFT073 protease 4 NP_754064.1 2006066 D 199310 CDS NP_754065.1 26248025 1036607 2008089..2009105 1 NC_004431.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2009105 ansA 1036607 ansA Escherichia coli CFT073 cytoplasmic asparaginase I NP_754065.1 2008089 D 199310 CDS NP_754066.2 161486213 1036608 2009116..2009757 1 NC_004431.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2009757 ydjB 1036608 ydjB Escherichia coli CFT073 nicotinamidase/pyrazinamidase NP_754066.2 2009116 D 199310 CDS NP_754067.1 26248027 1036610 complement(2009850..2011277) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1769; Escherichia coli O157:H7 ortholog: z2803; metabolite transporter 2011277 ydjE 1036610 ydjE Escherichia coli CFT073 metabolite transporter NP_754067.1 2009850 R 199310 CDS NP_754068.1 26248028 1036611 complement(2011326..2012084) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1770; Escherichia coli O157:H7 ortholog: z2808; transcriptional regulator YdjF 2012084 ydjF 1036611 ydjF Escherichia coli CFT073 transcriptional regulator YdjF NP_754068.1 2011326 R 199310 CDS NP_754069.1 26248029 1036613 complement(2012221..2013201) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1771; Escherichia coli O157:H7 ortholog: z2809; oxidoreductase ydjG 2013201 ydjG 1036613 ydjG Escherichia coli CFT073 oxidoreductase ydjG NP_754069.1 2012221 R 199310 CDS NP_754070.1 26248030 1036614 complement(2013211..2014179) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1772; Escherichia coli O157:H7 ortholog: z2810; sugar kinase ydjH 2014179 ydjH 1036614 ydjH Escherichia coli CFT073 sugar kinase ydjH NP_754070.1 2013211 R 199310 CDS NP_754071.1 26248031 1036615 complement(2014163..2014999) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1773; Escherichia coli O157:H7 ortholog: z2811; hypothetical protein 2014999 ydjI 1036615 ydjI Escherichia coli CFT073 hypothetical protein NP_754071.1 2014163 R 199310 CDS NP_754072.1 26248032 1036616 complement(2015020..2016063) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1774; Escherichia coli O157:H7 ortholog: z2812; hypothetical protein 2016063 ydjJ 1036616 ydjJ Escherichia coli CFT073 hypothetical protein NP_754072.1 2015020 R 199310 CDS NP_754073.1 26248033 1036617 complement(2016080..2017459) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1775; Escherichia coli O157:H7 ortholog: z2813; metabolite transporter 2017459 ydjK 1036617 ydjK Escherichia coli CFT073 metabolite transporter NP_754073.1 2016080 R 199310 CDS NP_754074.1 26248034 1036620 complement(2017344..2017496) 1 NC_004431.1 hypothetical protein 2017496 1036620 c2180 Escherichia coli CFT073 hypothetical protein NP_754074.1 2017344 R 199310 CDS NP_754075.1 26248035 1036621 complement(2017486..2018562) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1776; Escherichia coli O157:H7 ortholog: z2815; hypothetical protein 2018562 ydjL 1036621 ydjL Escherichia coli CFT073 hypothetical protein NP_754075.1 2017486 R 199310 CDS NP_754076.1 26248036 1036622 complement(2018932..2019249) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1777; Escherichia coli O157:H7 ortholog: z2816; hypothetical protein 2019249 yeaC 1036622 yeaC Escherichia coli CFT073 hypothetical protein NP_754076.1 2018932 R 199310 CDS NP_754077.1 26248037 1036623 complement(2019246..2019689) 1 NC_004431.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2019689 yeaA 1036623 yeaA Escherichia coli CFT073 methionine sulfoxide reductase B NP_754077.1 2019246 R 199310 CDS NP_754078.1 26248038 1036624 2019992..2020996 1 NC_004431.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 2020996 gapA 1036624 gapA Escherichia coli CFT073 glyceraldehyde-3-phosphate dehydrogenase NP_754078.1 2019992 D 199310 CDS NP_754079.1 26248039 1036625 2021059..2021964 1 NC_004431.1 Spots T26/PR37; Escherichia coli K-12 ortholog: b1780; Escherichia coli O157:H7 ortholog: z2820; hypothetical protein 2021964 yeaD 1036625 yeaD Escherichia coli CFT073 hypothetical protein NP_754079.1 2021059 D 199310 CDS NP_754080.1 26248040 1036626 complement(2022015..2022914) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1781; Escherichia coli O157:H7 ortholog: z2821; hypothetical protein 2022914 yeaE 1036626 yeaE Escherichia coli CFT073 hypothetical protein NP_754080.1 2022015 R 199310 CDS NP_754081.1 26248041 1036627 complement(2022959..2023705) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1782; Escherichia coli O157:H7 ortholog: z2822; MltA-interacting protein 2023705 yeaF 1036627 yeaF Escherichia coli CFT073 MltA-interacting protein NP_754081.1 2022959 R 199310 CDS NP_754082.1 26248042 1036628 2024141..2026075 1 NC_004431.1 Escherichia coli K-12 ortholog: b1783; Escherichia coli O157:H7 ortholog: z2823; hypothetical protein 2026075 yeaG 1036628 yeaG Escherichia coli CFT073 hypothetical protein NP_754082.1 2024141 D 199310 CDS NP_754083.1 26248043 1036629 2026188..2027471 1 NC_004431.1 Escherichia coli K-12 ortholog: b1784; Escherichia coli O157:H7 ortholog: z2824; hypothetical protein 2027471 yeaH 1036629 yeaH Escherichia coli CFT073 hypothetical protein NP_754083.1 2026188 D 199310 CDS NP_754084.1 26248044 1036630 2027618..2029093 1 NC_004431.1 Escherichia coli K-12 ortholog: b1785; Escherichia coli O157:H7 ortholog: z2825; hypothetical protein 2029093 yeaI 1036630 yeaI Escherichia coli CFT073 hypothetical protein NP_754084.1 2027618 D 199310 CDS NP_754085.3 347357894 1036631 2029094..2030764 1 NC_004431.1 Escherichia coli K-12 ortholog: b1786; Escherichia coli O157:H7 ortholog: z2826; hypothetical protein 2030764 yeaJ 1036631 yeaJ Escherichia coli CFT073 hypothetical protein NP_754085.3 2029094 D 199310 CDS NP_754086.1 26248046 1036632 2030807..2031310 1 NC_004431.1 Escherichia coli K-12 ortholog: b1787; Escherichia coli O157:H7 ortholog: z2827; hypothetical protein 2031310 yeaK 1036632 yeaK Escherichia coli CFT073 hypothetical protein NP_754086.1 2030807 D 199310 CDS NP_754087.1 26248047 1036633 complement(2031311..2031463) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1788; Escherichia coli O157:H7 ortholog: z2828; hypothetical protein 2031463 1036633 c2193 Escherichia coli CFT073 hypothetical protein NP_754087.1 2031311 R 199310 CDS NP_754088.1 26248048 1036635 2031585..2032031 1 NC_004431.1 Escherichia coli K-12 ortholog: b1789; Escherichia coli O157:H7 ortholog: z2829; hypothetical protein 2032031 yeaL 1036635 yeaL Escherichia coli CFT073 hypothetical protein NP_754088.1 2031585 D 199310 CDS NP_754089.1 26248049 1036636 complement(2031988..2032809) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1790; Escherichia coli O157:H7 ortholog: z2831; transcriptional regulator YeaM 2032809 yeaM 1036636 yeaM Escherichia coli CFT073 transcriptional regulator YeaM NP_754089.1 2031988 R 199310 CDS NP_754090.1 26248050 1036637 2032906..2034087 1 NC_004431.1 Escherichia coli K-12 ortholog: b1791; Escherichia coli O157:H7 ortholog: z2833; transport protein YeaN 2034087 yeaN 1036637 yeaN Escherichia coli CFT073 transport protein YeaN NP_754090.1 2032906 D 199310 CDS NP_754091.3 347357893 1036638 2034121..2034489 1 NC_004431.1 Escherichia coli K-12 ortholog: b1792; Escherichia coli O157:H7 ortholog: z2834; hypothetical protein 2034489 yeaO 1036638 yeaO Escherichia coli CFT073 hypothetical protein NP_754091.3 2034121 D 199310 CDS NP_754092.1 26248052 1036641 complement(2034511..2034765) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1793; Escherichia coli O157:H7 ortholog: z2835; hypothetical protein 2034765 yoaF 1036641 yoaF Escherichia coli CFT073 hypothetical protein NP_754092.1 2034511 R 199310 CDS NP_754093.1 26248053 1036642 2034819..2035973 1 NC_004431.1 Escherichia coli K-12 ortholog: b1794; Escherichia coli O157:H7 ortholog: z2836; hypothetical protein 2035973 yeaP 1036642 yeaP Escherichia coli CFT073 hypothetical protein NP_754093.1 2034819 D 199310 CDS NP_754094.1 26248054 1036643 complement(2036241..2036489) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1795; Escherichia coli O157:H7 ortholog: z2837; hypothetical protein 2036489 yeaQ 1036643 yeaQ Escherichia coli CFT073 hypothetical protein NP_754094.1 2036241 R 199310 CDS NP_754095.1 26248055 1036644 complement(2036501..2036623) 1 NC_004431.1 hypothetical protein 2036623 1036644 c2201 Escherichia coli CFT073 hypothetical protein NP_754095.1 2036501 R 199310 CDS NP_754096.1 26248056 1036645 complement(2036637..2036819) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1796; Escherichia coli O157:H7 ortholog: z2838; hypothetical protein 2036819 yoaG 1036645 yoaG Escherichia coli CFT073 hypothetical protein NP_754096.1 2036637 R 199310 CDS NP_754097.1 26248057 1036646 2036655..2037146 1 NC_004431.1 hypothetical protein 2037146 1036646 c2203 Escherichia coli CFT073 hypothetical protein NP_754097.1 2036655 D 199310 CDS NP_754098.1 26248058 1036647 complement(2036823..2037182) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1797; Escherichia coli O157:H7 ortholog: z2839; hypothetical protein 2037182 yeaR 1036647 yeaR Escherichia coli CFT073 hypothetical protein NP_754098.1 2036823 R 199310 CDS NP_754099.1 26248059 1036648 complement(2037355..2037993) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1798; Escherichia coli O157:H7 ortholog: z2841; leucine export protein LeuE 2037993 yeaS 1036648 yeaS Escherichia coli CFT073 leucine export protein LeuE NP_754099.1 2037355 R 199310 CDS NP_754100.1 26248060 1036649 complement(2038120..2038452) 1 NC_004431.1 Residues 56 to 110 of 110 are 94.54 pct identical to residues 260 to 314 of 314 from GenPept.129 : >gb|AAG56788.1|AE005402_14 (AE005402) transcriptional regulator LYSR-type [Escherichia coli O157:H7 EDL933]; hypothetical protein 2038452 1036649 c2206 Escherichia coli CFT073 hypothetical protein NP_754100.1 2038120 R 199310 CDS NP_754101.1 26248061 1036651 2038276..2038446 1 NC_004431.1 Residues 5 to 56 of 56 are 92.30 pct identical to residues 121 to 172 of 361 from GenPept.129 : >gb|AAG56789.1|AE005402_15 (AE005402) tartrate dehydrogenase [Escherichia coli O157:H7 EDL933]; hypothetical protein 2038446 1036651 c2207 Escherichia coli CFT073 hypothetical protein NP_754101.1 2038276 D 199310 CDS NP_754102.1 26248062 1036652 complement(2038536..2039663) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1804; Escherichia coli O157:H7 ortholog: z2847; ribonuclease D 2039663 rnd 1036652 rnd Escherichia coli CFT073 ribonuclease D NP_754102.1 2038536 R 199310 CDS NP_754103.1 26248063 1036653 complement(2039733..2041484) 1 NC_004431.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2041484 fadD 1036653 fadD Escherichia coli CFT073 long-chain-fatty-acid--CoA ligase NP_754103.1 2039733 R 199310 CDS NP_754104.1 26248064 1036656 complement(2041623..2042204) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1806; Escherichia coli O157:H7 ortholog: z2849; lipoprotein yeaY 2042204 yeaY 1036656 yeaY Escherichia coli CFT073 lipoprotein yeaY NP_754104.1 2041623 R 199310 CDS NP_754105.1 26248065 1036657 complement(2042244..2042939) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1807; Escherichia coli O157:H7 ortholog: z2850; hypothetical protein 2042939 yeaZ 1036657 yeaZ Escherichia coli CFT073 hypothetical protein NP_754105.1 2042244 R 199310 CDS NP_754106.1 26248066 1036659 complement(2042997..2044907) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1808; Escherichia coli O157:H7 ortholog: z2851; ATP-dependent helicase yoaA 2044907 1036659 c2212 Escherichia coli CFT073 ATP-dependent helicase yoaA NP_754106.1 2042997 R 199310 CDS NP_754107.1 26248067 1036666 2044991..2045383 1 NC_004431.1 Escherichia coli K-12 ortholog: b1809; Escherichia coli O157:H7 ortholog: z2852; hypothetical protein 2045383 yoaB 1036666 yoaB Escherichia coli CFT073 hypothetical protein NP_754107.1 2044991 D 199310 CDS NP_754108.1 26248068 1036668 2045745..2046104 1 NC_004431.1 Escherichia coli K-12 ortholog: b1810; Escherichia coli O157:H7 ortholog: z2853; hypothetical protein 2046104 yoaC 1036668 yoaC Escherichia coli CFT073 hypothetical protein NP_754108.1 2045745 D 199310 CDS NP_754109.1 26248069 1036669 2046221..2046385 1 NC_004431.1 hypothetical protein 2046385 1036669 c2215 Escherichia coli CFT073 hypothetical protein NP_754109.1 2046221 D 199310 CDS NP_754110.1 26248070 1036677 complement(2046224..2046403) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1811; Escherichia coli O157:H7 ortholog: z2854; hypothetical protein 2046403 yoaH 1036677 yoaH Escherichia coli CFT073 hypothetical protein NP_754110.1 2046224 R 199310 CDS NP_754111.1 26248071 1036679 2046477..2047838 1 NC_004431.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 2047838 pabB 1036679 pabB Escherichia coli CFT073 para-aminobenzoate synthase component I NP_754111.1 2046477 D 199310 CDS NP_754112.1 26248072 1036681 2047842..2048420 1 NC_004431.1 Escherichia coli K-12 ortholog: b1813; Escherichia coli O157:H7 ortholog: z2856; hypothetical protein 2048420 yeaB 1036681 yeaB Escherichia coli CFT073 hypothetical protein NP_754112.1 2047842 D 199310 CDS NP_754113.1 26248073 1036688 2048604..2049968 1 NC_004431.1 Escherichia coli K-12 ortholog: b1814; Escherichia coli O157:H7 ortholog: z2857; L-serine dehydratase 1 2049968 sdaA 1036688 sdaA Escherichia coli CFT073 L-serine dehydratase 1 NP_754113.1 2048604 D 199310 CDS NP_754114.1 26248074 1036694 2049996..2050124 1 NC_004431.1 hypothetical protein 2050124 1036694 c2220 Escherichia coli CFT073 hypothetical protein NP_754114.1 2049996 D 199310 CDS NP_754115.1 26248075 1036695 2050069..2051697 1 NC_004431.1 Escherichia coli K-12 ortholog: b1815; Escherichia coli O157:H7 ortholog: z2858; hypothetical protein 2051697 yoaD 1036695 yoaD Escherichia coli CFT073 hypothetical protein NP_754115.1 2050069 D 199310 CDS NP_754116.1 26248076 1036699 complement(2051701..2053257) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1816; Escherichia coli O157:H7 ortholog: z2859; hypothetical protein 2053257 yoaE 1036699 yoaE Escherichia coli CFT073 hypothetical protein NP_754116.1 2051701 R 199310 CDS NP_754117.1 26248077 1036702 2053720..2054691 1 NC_004431.1 EIIAB-Man; Escherichia coli K-12 ortholog: b1817; Escherichia coli O157:H7 ortholog: z2860; PTS system, mannose-specific IIAB component 2054691 manX 1036702 manX Escherichia coli CFT073 PTS system, mannose-specific IIAB component NP_754117.1 2053720 D 199310 CDS NP_754118.1 26248078 1036703 2054754..2055554 1 NC_004431.1 EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z2861; PTS system, mannose-specific IIC component 2055554 manY 1036703 manY Escherichia coli CFT073 PTS system, mannose-specific IIC component NP_754118.1 2054754 D 199310 CDS NP_754119.1 26248079 1036704 complement(2054850..2055611) 1 NC_004431.1 hypothetical protein 2055611 1036704 c2225 Escherichia coli CFT073 hypothetical protein NP_754119.1 2054850 R 199310 CDS NP_754120.1 26248080 1036705 2055558..2056418 1 NC_004431.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2056418 manZ 1036705 manZ Escherichia coli CFT073 PTS system mannose-specific transporter subunit IID NP_754120.1 2055558 D 199310 CDS NP_754121.1 26248081 1036706 2056473..2056931 1 NC_004431.1 Escherichia coli K-12 ortholog: b1820; Escherichia coli O157:H7 ortholog: z2863; hypothetical protein 2056931 yobD 1036706 yobD Escherichia coli CFT073 hypothetical protein NP_754121.1 2056473 D 199310 CDS NP_754122.1 26248082 1036710 2057306..2057926 1 NC_004431.1 membrane protein YebN; hypothetical protein 2057926 yebN 1036710 yebN Escherichia coli CFT073 hypothetical protein NP_754122.1 2057306 D 199310 CDS NP_754123.1 26248083 1036714 complement(2057923..2058732) 1 NC_004431.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 2058732 rrmA 1036714 rrmA Escherichia coli CFT073 23S rRNA methyltransferase NP_754123.1 2057923 R 199310 CDS NP_754124.1 26248084 1036717 2058862..2059149 1 NC_004431.1 hypothetical protein 2059149 1036717 c2230 Escherichia coli CFT073 hypothetical protein NP_754124.1 2058862 D 199310 CDS NP_754125.1 26248085 1036718 complement(2058898..2059107) 1 NC_004431.1 CSP-C; Escherichia coli K-12 ortholog: b1823; Escherichia coli O157:H7 ortholog: z2868; cold shock-like protein CspC 2059107 cspC 1036718 cspC Escherichia coli CFT073 cold shock-like protein CspC NP_754125.1 2058898 R 199310 CDS NP_754126.1 26248086 1036721 complement(2059120..2059263) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1824; Escherichia coli O157:H7 ortholog: z2869; hypothetical protein 2059263 yobF 1036721 yobF Escherichia coli CFT073 hypothetical protein NP_754126.1 2059120 R 199310 CDS NP_754127.1 26248087 1036728 complement(2059933..2060220) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1825; Escherichia coli O157:H7 ortholog: z2871; hypothetical protein 2060220 yebO 1036728 yebO Escherichia coli CFT073 hypothetical protein NP_754127.1 2059933 R 199310 CDS NP_754128.1 26248088 1036740 complement(2060295..2060438) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1826; Escherichia coli O157:H7 ortholog: z2872; hypothetical protein 2060438 yobG 1036740 yobG Escherichia coli CFT073 hypothetical protein NP_754128.1 2060295 R 199310 CDS NP_754129.1 26248089 1036748 2060597..2060836 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2873; hypothetical protein 2060836 1036748 c2235 Escherichia coli CFT073 hypothetical protein NP_754129.1 2060597 D 199310 CDS NP_754130.1 26248090 1036749 complement(2060980..2061771) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1827; Escherichia coli O157:H7 ortholog: z2874; transcriptional regulator kdgR 2061771 1036749 c2236 Escherichia coli CFT073 transcriptional regulator kdgR NP_754130.1 2060980 R 199310 CDS NP_754131.1 26248091 1036750 2061837..2063321 1 NC_004431.1 Escherichia coli K-12 ortholog: b1828; Escherichia coli O157:H7 ortholog: z2875; transport protein YebQ 2063321 yebQ 1036750 yebQ Escherichia coli CFT073 transport protein YebQ NP_754131.1 2061837 D 199310 CDS NP_754132.1 26248092 1036752 complement(2063367..2064248) 1 NC_004431.1 metalloprotease; heat shock protein HtpX 2064248 htpX 1036752 htpX Escherichia coli CFT073 heat shock protein HtpX NP_754132.1 2063367 R 199310 CDS NP_754133.1 26248093 1036753 complement(2064440..2066488) 1 NC_004431.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2066488 prc 1036753 prc Escherichia coli CFT073 carboxy-terminal protease NP_754133.1 2064440 R 199310 CDS NP_754134.1 26248094 1036754 complement(2066508..2067206) 1 NC_004431.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 2067206 proQ 1036754 proQ Escherichia coli CFT073 solute/DNA competence effector NP_754134.1 2066508 R 199310 CDS NP_754135.1 26248095 1036755 complement(2067303..2067749) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1832; Escherichia coli O157:H7 ortholog: z2879; hypothetical protein 2067749 1036755 c2241 Escherichia coli CFT073 hypothetical protein NP_754135.1 2067303 R 199310 CDS NP_754136.1 26248096 1036756 2067863..2069218 1 NC_004431.1 Escherichia coli K-12 ortholog: b1833; Escherichia coli O157:H7 ortholog: z2880; hypothetical protein 2069218 yebS 1036756 yebS Escherichia coli CFT073 hypothetical protein NP_754136.1 2067863 D 199310 CDS NP_754137.1 26248097 1036758 2069145..2071820 1 NC_004431.1 Escherichia coli K-12 ortholog: b1834; Escherichia coli O157:H7 ortholog: z2881; hypothetical protein 2071820 yebT 1036758 yebT Escherichia coli CFT073 hypothetical protein NP_754137.1 2069145 D 199310 CDS NP_754138.1 26248098 1036759 2071894..2073339 1 NC_004431.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2073339 yebU 1036759 yebU Escherichia coli CFT073 rRNA (cytosine-C(5)-)-methyltransferase RsmF NP_754138.1 2071894 D 199310 CDS NP_754139.1 26248099 1036760 2073442..2073693 1 NC_004431.1 Escherichia coli K-12 ortholog: b1836; Escherichia coli O157:H7 ortholog: z2883; hypothetical protein 2073693 yebV 1036760 yebV Escherichia coli CFT073 hypothetical protein NP_754139.1 2073442 D 199310 CDS NP_754140.1 26248100 1036764 2073714..2073989 1 NC_004431.1 Escherichia coli K-12 ortholog: b1837; Escherichia coli O157:H7 ortholog: z2884; hypothetical protein 2073989 yebW 1036764 yebW Escherichia coli CFT073 hypothetical protein NP_754140.1 2073714 D 199310 CDS NP_754141.1 26248101 1036766 complement(2073990..2074649) 1 NC_004431.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2074649 pphA 1036766 pphA Escherichia coli CFT073 serine/threonine protein phosphatase 1 NP_754141.1 2073990 R 199310 CDS NP_754142.1 26248102 1036767 complement(2074871..2075023) 1 NC_004431.1 hypothetical protein 2075023 1036767 c2248 Escherichia coli CFT073 hypothetical protein NP_754142.1 2074871 R 199310 CDS NP_754143.1 26248103 1036769 complement(2075041..2075382) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1839; Escherichia coli O157:H7 ortholog: z2887; hypothetical protein 2075382 yebY 1036769 yebY Escherichia coli CFT073 hypothetical protein NP_754143.1 2075041 R 199310 CDS NP_754144.1 26248104 1036770 complement(2075395..2076267) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1840; Escherichia coli O157:H7 ortholog: z2888; hypothetical protein 2076267 yebZ 1036770 yebZ Escherichia coli CFT073 hypothetical protein NP_754144.1 2075395 R 199310 CDS NP_754145.1 26248105 1036771 complement(2076271..2076645) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1841; Escherichia coli O157:H7 ortholog: z2889; hypothetical protein 2076645 1036771 c2251 Escherichia coli CFT073 hypothetical protein NP_754145.1 2076271 R 199310 CDS NP_754146.3 347357892 1036772 2076697..2077014 1 NC_004431.1 Escherichia coli K-12 ortholog: b1842; Escherichia coli O157:H7 ortholog: z2891; DNA polymerase III subunit theta 2077014 holE 1036772 holE Escherichia coli CFT073 DNA polymerase III subunit theta NP_754146.3 2076697 D 199310 CDS NP_754147.1 26248107 1036776 2077117..2077773 1 NC_004431.1 Escherichia coli K-12 ortholog: b1843; Escherichia coli O157:H7 ortholog: z2893; hypothetical protein 2077773 yobB 1036776 yobB Escherichia coli CFT073 hypothetical protein NP_754147.1 2077117 D 199310 CDS NP_754148.2 161486210 1036778 2077797..2078459 1 NC_004431.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2078459 1036778 c2254 Escherichia coli CFT073 exodeoxyribonuclease X NP_754148.2 2077797 D 199310 CDS NP_754149.1 26248109 1036779 complement(2078456..2078851) 1 NC_004431.1 Residues 1 to 131 of 131 are 96.94 pct identical to residues 556 to 686 of 686 from GenPept.129 : >gb|AAC74915.1| (AE000278) protease II [Escherichia coli K12]; hypothetical protein 2078851 1036779 c2255 Escherichia coli CFT073 hypothetical protein NP_754149.1 2078456 R 199310 CDS NP_754150.1 26248110 1036782 complement(2078852..2080516) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1845; Escherichia coli O157:H7 ortholog: z2896; protease II 2080516 ptrB 1036782 ptrB Escherichia coli CFT073 protease II NP_754150.1 2078852 R 199310 CDS NP_754151.1 26248111 1036784 2080602..2081204 1 NC_004431.1 hypothetical protein 2081204 1036784 c2257 Escherichia coli CFT073 hypothetical protein NP_754151.1 2080602 D 199310 CDS NP_754152.1 26248112 1036785 complement(2080725..2081384) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1846; Escherichia coli O157:H7 ortholog: z2897; hypothetical protein 2081384 yebE 1036785 yebE Escherichia coli CFT073 hypothetical protein NP_754152.1 2080725 R 199310 CDS NP_754153.1 26248113 1036792 complement(2081711..2082079) 1 NC_004431.1 secreted protein; unknown function; hypothetical protein 2082079 yebF 1036792 yebF Escherichia coli CFT073 hypothetical protein NP_754153.1 2081711 R 199310 CDS NP_754154.1 26248114 1036797 complement(2082134..2082424) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1848; Escherichia coli O157:H7 ortholog: z2900; DNA damage-inducible protein YebG 2082424 yebG 1036797 yebG Escherichia coli CFT073 DNA damage-inducible protein YebG NP_754154.1 2082134 R 199310 CDS NP_754155.1 26248115 1036805 complement(2083792..2084433) 1 NC_004431.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2084433 eda 1036805 eda Escherichia coli CFT073 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase NP_754155.1 2083792 R 199310 CDS NP_754156.2 161486209 1036806 complement(2084470..2086281) 1 NC_004431.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2086281 edd 1036806 edd Escherichia coli CFT073 phosphogluconate dehydratase NP_754156.2 2084470 R 199310 CDS NP_754157.1 26248117 1036807 complement(2086516..2087991) 1 NC_004431.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2087991 zwf 1036807 zwf Escherichia coli CFT073 glucose-6-phosphate 1-dehydrogenase NP_754157.1 2086516 R 199310 CDS NP_754158.1 26248118 1036810 complement(2088157..2088306) 1 NC_004431.1 hypothetical protein 2088306 1036810 c2266 Escherichia coli CFT073 hypothetical protein NP_754158.1 2088157 R 199310 CDS NP_754159.1 26248119 1036812 2088329..2089198 1 NC_004431.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2089198 yebK 1036812 yebK Escherichia coli CFT073 DNA-binding transcriptional regulator HexR NP_754159.1 2088329 D 199310 CDS NP_754160.2 161486208 1036813 2089326..2090768 1 NC_004431.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2090768 pykA 1036813 pykA Escherichia coli CFT073 pyruvate kinase NP_754160.2 2089326 D 199310 CDS NP_754161.1 26248121 1036816 complement(2090900..2091871) 1 NC_004431.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2091871 msbB 1036816 msbB Escherichia coli CFT073 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase NP_754161.1 2090900 R 199310 CDS NP_754162.1 26248122 1036817 complement(2091990..2093312) 1 NC_004431.1 ORFU; Escherichia coli K-12 ortholog: b1856; Escherichia coli O157:H7 ortholog: z2908; hypothetical protein 2093312 yebA 1036817 yebA Escherichia coli CFT073 hypothetical protein NP_754162.1 2091990 R 199310 CDS NP_754163.2 161486207 1036822 complement(2093328..2094260) 1 NC_004431.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 2094260 znuA 1036822 znuA Escherichia coli CFT073 high-affinity zinc transporter periplasmic component NP_754163.2 2093328 R 199310 CDS NP_754164.1 26248124 1036825 2094339..2095094 1 NC_004431.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2095094 znuC 1036825 znuC Escherichia coli CFT073 high-affinity zinc transporter ATPase NP_754164.1 2094339 D 199310 CDS NP_754165.1 26248125 1036826 2095091..2095876 1 NC_004431.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2095876 znuB 1036826 znuB Escherichia coli CFT073 high-affinity zinc transporter membrane component NP_754165.1 2095091 D 199310 CDS NP_754166.1 26248126 1036828 complement(2096023..2097033) 1 NC_004431.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2097033 ruvB 1036828 ruvB Escherichia coli CFT073 Holliday junction DNA helicase RuvB NP_754166.1 2096023 R 199310 CDS NP_754167.1 26248127 1036829 complement(2097042..2097653) 1 NC_004431.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2097653 ruvA 1036829 ruvA Escherichia coli CFT073 Holliday junction DNA helicase RuvA NP_754167.1 2097042 R 199310 CDS NP_754168.2 161486206 1036830 2097929..2098531 1 NC_004431.1 Escherichia coli K-12 ortholog: b1862; Escherichia coli O157:H7 ortholog: z2914; hypothetical protein 2098531 yebB 1036830 yebB Escherichia coli CFT073 hypothetical protein NP_754168.2 2097929 D 199310 CDS NP_754169.1 26248129 1036831 complement(2098533..2099057) 1 NC_004431.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2099057 ruvC 1036831 ruvC Escherichia coli CFT073 Holliday junction resolvase NP_754169.1 2098533 R 199310 CDS NP_754170.1 26248130 1036832 complement(2099089..2099829) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1864; Escherichia coli O157:H7 ortholog: z2916; hypothetical protein 2099829 yebC 1036832 yebC Escherichia coli CFT073 hypothetical protein NP_754170.1 2099089 R 199310 CDS NP_754171.1 26248131 1036833 complement(2099858..2100301) 1 NC_004431.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2100301 ntpA 1036833 ntpA Escherichia coli CFT073 dATP pyrophosphohydrolase NP_754171.1 2099858 R 199310 CDS NP_754172.1 26248132 1036836 complement(2100303..2102075) 1 NC_004431.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2102075 aspS 1036836 aspS Escherichia coli CFT073 aspartyl-tRNA synthetase NP_754172.1 2100303 R 199310 CDS NP_754173.2 161486205 1036839 2102385..2102951 1 NC_004431.1 Escherichia coli K-12 ortholog: b1867; Escherichia coli O157:H7 ortholog: z2920; hypothetical protein 2102951 yecD 1036839 yecD Escherichia coli CFT073 hypothetical protein NP_754173.2 2102385 D 199310 CDS NP_754174.1 26248134 1036847 2102948..2103766 1 NC_004431.1 Escherichia coli K-12 ortholog: b1868; Escherichia coli O157:H7 ortholog: z2921; hypothetical protein 2103766 yecE 1036847 yecE Escherichia coli CFT073 hypothetical protein NP_754174.1 2102948 D 199310 CDS NP_754175.3 347357891 1036848 2103789..2104214 1 NC_004431.1 Escherichia coli K-12 ortholog: b1869; Escherichia coli O157:H7 ortholog: z2922; hypothetical protein 2104214 yecN 1036848 yecN Escherichia coli CFT073 hypothetical protein NP_754175.3 2103789 D 199310 CDS NP_754176.1 26248136 1036849 2104255..2104998 1 NC_004431.1 Escherichia coli K-12 ortholog: b1870; Escherichia coli O157:H7 ortholog: z2923; hypothetical protein 2104998 yecO 1036849 yecO Escherichia coli CFT073 hypothetical protein NP_754176.1 2104255 D 199310 CDS NP_754177.1 26248137 1036852 2104995..2105966 1 NC_004431.1 Escherichia coli K-12 ortholog: b1871; Escherichia coli O157:H7 ortholog: z2924; hypothetical protein 2105966 yecP 1036852 yecP Escherichia coli CFT073 hypothetical protein NP_754177.1 2104995 D 199310 CDS NP_754178.1 26248138 1036854 complement(2106131..2108578) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1872; Escherichia coli O157:H7 ortholog: z2925; trimethylamine-N-oxide reductase 2 2108578 bisZ 1036854 bisZ Escherichia coli CFT073 trimethylamine-N-oxide reductase 2 NP_754178.1 2106131 R 199310 CDS NP_754179.1 26248139 1036855 complement(2108585..2109685) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1873; Escherichia coli O157:H7 ortholog: z2926; cytochrome c-type protein torY 2109685 yecK 1036855 yecK Escherichia coli CFT073 cytochrome c-type protein torY NP_754179.1 2108585 R 199310 CDS NP_754180.1 26248140 1036858 complement(2109591..2109722) 1 NC_004431.1 hypothetical protein 2109722 1036858 c2288 Escherichia coli CFT073 hypothetical protein NP_754180.1 2109591 R 199310 CDS NP_754181.1 26248141 1036859 complement(2110073..2110819) 1 NC_004431.1 Residues 103 to 248 of 248 are 97.26 pct identical to residues 1 to 146 of 146 from MG1655 : b1874; copper homeostasis protein CutC 2110819 1036859 c2289 Escherichia coli CFT073 copper homeostasis protein CutC NP_754181.1 2110073 R 199310 CDS NP_754182.1 26248142 1036864 complement(2110833..2111405) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1875; Escherichia coli O157:H7 ortholog: z2928; hypothetical protein 2111405 yecM 1036864 yecM Escherichia coli CFT073 hypothetical protein NP_754182.1 2110833 R 199310 CDS NP_754183.1 26248143 1036865 2111615..2113348 1 NC_004431.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2113348 argS 1036865 argS Escherichia coli CFT073 arginyl-tRNA synthetase NP_754183.1 2111615 D 199310 CDS NP_754184.1 26248144 1036868 complement(2113401..2113793) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1878; Escherichia coli O157:H7 ortholog: z2931; flagellar protein flhE 2113793 flhE 1036868 flhE Escherichia coli CFT073 flagellar protein flhE NP_754184.1 2113401 R 199310 CDS NP_754185.3 347357890 1036871 complement(2113793..2115946) 1 NC_004431.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2115946 flhA 1036871 flhA Escherichia coli CFT073 flagellar biosynthesis protein FlhA NP_754185.3 2113793 R 199310 CDS NP_754186.1 26248146 1036873 complement(2115864..2117012) 1 NC_004431.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2117012 flhB 1036873 flhB Escherichia coli CFT073 flagellar biosynthesis protein FlhB NP_754186.1 2115864 R 199310 CDS NP_754187.1 26248147 1036878 2117045..2117191 1 NC_004431.1 hypothetical protein 2117191 1036878 c2295 Escherichia coli CFT073 hypothetical protein NP_754187.1 2117045 D 199310 CDS NP_754188.2 161486202 1036881 complement(2117221..2117865) 1 NC_004431.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2117865 cheZ 1036881 cheZ Escherichia coli CFT073 chemotaxis regulator CheZ NP_754188.2 2117221 R 199310 CDS NP_754189.1 26248149 1036883 complement(2117876..2118265) 1 NC_004431.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2118265 cheY 1036883 cheY Escherichia coli CFT073 chemotaxis regulatory protein CheY NP_754189.1 2117876 R 199310 CDS NP_754190.1 26248150 1036885 complement(2118280..2119329) 1 NC_004431.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2119329 cheB 1036885 cheB Escherichia coli CFT073 chemotaxis-specific methylesterase NP_754190.1 2118280 R 199310 CDS NP_754191.1 26248151 1036886 complement(2119332..2120192) 1 NC_004431.1 methylates the MCP; chemotaxis methyltransferase CheR 2120192 cheR 1036886 cheR Escherichia coli CFT073 chemotaxis methyltransferase CheR NP_754191.1 2119332 R 199310 CDS NP_754192.1 26248152 1036889 complement(2120318..2120440) 1 NC_004431.1 Residues 2 to 34 of 40 are 93.93 pct identical to residues 1 to 33 of 535 from GenPept.129 : >gb|AAA23567.1| (M13463) sensory transducer protein [Escherichia coli]; hypothetical protein 2120440 1036889 c2300 Escherichia coli CFT073 hypothetical protein NP_754192.1 2120318 R 199310 CDS NP_754193.1 26248153 1036890 complement(2120483..2122165) 1 NC_004431.1 MCP-II; Escherichia coli K-12 ortholog: b1886; Escherichia coli O157:H7 ortholog: z2940; methyl-accepting chemotaxis protein II 2122165 tar 1036890 tar Escherichia coli CFT073 methyl-accepting chemotaxis protein II NP_754193.1 2120483 R 199310 CDS NP_754194.1 26248154 1036897 complement(2122289..2122792) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1887; Escherichia coli O157:H7 ortholog: z2941; purine-binding chemotaxis protein 2122792 cheW 1036897 cheW Escherichia coli CFT073 purine-binding chemotaxis protein NP_754194.1 2122289 R 199310 CDS NP_754195.1 26248155 1036900 complement(2122813..2124831) 1 NC_004431.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 2124831 cheA 1036900 cheA Escherichia coli CFT073 chemotaxis protein CheA NP_754195.1 2122813 R 199310 CDS NP_754196.1 26248156 1036903 complement(2124782..2125708) 1 NC_004431.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2125708 motB 1036903 motB Escherichia coli CFT073 flagellar motor protein MotB NP_754196.1 2124782 R 199310 CDS NP_754197.1 26248157 1036906 complement(2125705..2126592) 1 NC_004431.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2126592 motA 1036906 motA Escherichia coli CFT073 flagellar motor protein MotA NP_754197.1 2125705 R 199310 CDS NP_754198.1 26248158 1036907 complement(2126718..2127296) 1 NC_004431.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2127296 flhC 1036907 flhC Escherichia coli CFT073 transcriptional activator FlhC NP_754198.1 2126718 R 199310 CDS YP_004853812.1 347357912 1036909 complement(2126795..2126941) 1 NC_004431.1 hypothetical protein 2126941 1036909 c2307 Escherichia coli CFT073 hypothetical protein YP_004853812.1 2126795 R 199310 CDS NP_754200.1 26248160 1036911 complement(2127299..2127658) 1 NC_004431.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2127658 flhD 1036911 flhD Escherichia coli CFT073 transcriptional activator FlhD NP_754200.1 2127299 R 199310 CDS NP_754201.1 26248161 1036912 2128429..2128857 1 NC_004431.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2128857 yecG 1036912 yecG Escherichia coli CFT073 universal stress protein UspC NP_754201.1 2128429 D 199310 CDS NP_754202.1 26248162 1036913 complement(2128864..2130297) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1896; Escherichia coli O157:H7 ortholog: z2949; trehalose-6-phosphate synthase 2130297 otsA 1036913 otsA Escherichia coli CFT073 trehalose-6-phosphate synthase NP_754202.1 2128864 R 199310 CDS NP_754203.1 26248163 1036914 complement(2130263..2131120) 1 NC_004431.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2131120 otsB 1036914 otsB Escherichia coli CFT073 trehalose-6-phosphate phosphatase NP_754203.1 2130263 R 199310 CDS NP_754204.1 26248164 1036915 complement(2131230..2132219) 1 NC_004431.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2132219 araH 1036915 araH Escherichia coli CFT073 L-arabinose transporter permease NP_754204.1 2131230 R 199310 CDS NP_754205.2 161486201 1036917 complement(2132231..2133745) 1 NC_004431.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2133745 araG 1036917 araG Escherichia coli CFT073 L-arabinose transporter ATP-binding protein NP_754205.2 2132231 R 199310 CDS NP_754206.1 26248166 1036918 complement(2133815..2134855) 1 NC_004431.1 ABP; Escherichia coli K-12 ortholog: b1901; Escherichia coli O157:H7 ortholog: z2954; L-arabinose-binding periplasmic protein 2134855 araF 1036918 araF Escherichia coli CFT073 L-arabinose-binding periplasmic protein NP_754206.1 2133815 R 199310 CDS NP_754207.1 26248167 1036921 2135601..2136104 1 NC_004431.1 Escherichia coli K-12 ortholog: b1902; Escherichia coli O157:H7 ortholog: z2956; ferritin 2136104 yecI 1036921 yecI Escherichia coli CFT073 ferritin NP_754207.1 2135601 D 199310 CDS NP_754208.1 26248168 1036925 complement(2136183..2136434) 1 NC_004431.1 Residues 1 to 83 of 83 are 100.00 pct identical to residues 1 to 83 of 83 from SwissProt.40 : >sp|P52092|YECJ_ECOLI Hypothetical protein yecJ; hypothetical protein 2136434 1036925 c2316 Escherichia coli CFT073 hypothetical protein NP_754208.1 2136183 R 199310 CDS NP_754209.1 26248169 1036929 2136546..2136692 1 NC_004431.1 hypothetical protein 2136692 1036929 c2317 Escherichia coli CFT073 hypothetical protein NP_754209.1 2136546 D 199310 CDS NP_754210.1 26248170 1036930 complement(2136549..2136695) 1 NC_004431.1 hypothetical protein 2136695 1036930 c2318 Escherichia coli CFT073 hypothetical protein NP_754210.1 2136549 R 199310 CDS NP_754211.1 26248171 1036931 2136898..2137221 1 NC_004431.1 Escherichia coli K-12 ortholog: b1904; Escherichia coli O157:H7 ortholog: z2959; hypothetical protein 2137221 yecR 1036931 yecR Escherichia coli CFT073 hypothetical protein NP_754211.1 2136898 D 199310 CDS NP_754212.1 26248172 1036932 complement(2137231..2137368) 1 NC_004431.1 hypothetical protein 2137368 1036932 c2320 Escherichia coli CFT073 hypothetical protein NP_754212.1 2137231 R 199310 CDS NP_754213.1 26248173 1036934 2137378..2137890 1 NC_004431.1 cytoplasmic iron storage protein; ferritin 2137890 ftn 1036934 ftn Escherichia coli CFT073 ferritin NP_754213.1 2137378 D 199310 CDS NP_754214.1 26248174 1036936 complement(2137928..2138167) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1906; Escherichia coli O157:H7 ortholog: z2962; hypothetical protein 2138167 yecH 1036936 yecH Escherichia coli CFT073 hypothetical protein NP_754214.1 2137928 R 199310 CDS NP_754215.1 26248175 1036938 2138358..2139569 1 NC_004431.1 Tyrosine permease; Escherichia coli K-12 ortholog: b1907; Escherichia coli O157:H7 ortholog: z2963; tyrosine transporter 2139569 tyrP 1036938 tyrP Escherichia coli CFT073 tyrosine transporter NP_754215.1 2138358 D 199310 CDS NP_754216.1 26248176 1036940 complement(2139631..2140296) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1908; Escherichia coli O157:H7 ortholog: z2964; hypothetical protein 2140296 yecA 1036940 yecA Escherichia coli CFT073 hypothetical protein NP_754216.1 2139631 R 199310 CDS NP_754217.1 26248177 1036953 complement(2140945..2141493) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1912; Escherichia coli O157:H7 ortholog: z3000; phosphatidylglycerophosphate synthetase 2141493 pgsA 1036953 pgsA Escherichia coli CFT073 phosphatidylglycerophosphate synthetase NP_754217.1 2140945 R 199310 CDS NP_754218.1 26248178 1036954 complement(2141550..2143382) 1 NC_004431.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2143382 uvrC 1036954 uvrC Escherichia coli CFT073 excinuclease ABC subunit C NP_754218.1 2141550 R 199310 CDS NP_754219.1 26248179 1036955 complement(2143379..2144035) 1 NC_004431.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2144035 uvrY 1036955 uvrY Escherichia coli CFT073 response regulator NP_754219.1 2143379 R 199310 CDS NP_754220.1 26248180 1036956 complement(2144274..2144402) 1 NC_004431.1 hypothetical protein 2144402 1036956 c2328 Escherichia coli CFT073 hypothetical protein NP_754220.1 2144274 R 199310 CDS NP_754221.1 26248181 1036957 2144494..2144718 1 NC_004431.1 Escherichia coli K-12 ortholog: b1915; Escherichia coli O157:H7 ortholog: z3003; hypothetical protein 2144718 yecF 1036957 yecF Escherichia coli CFT073 hypothetical protein NP_754221.1 2144494 D 199310 CDS NP_754222.2 161486200 1036959 complement(2144786..2145508) 1 NC_004431.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2145508 sdiA 1036959 sdiA Escherichia coli CFT073 DNA-binding transcriptional activator SdiA NP_754222.2 2144786 R 199310 CDS NP_754223.1 26248183 1036960 complement(2145738..2146490) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1917; Escherichia coli O157:H7 ortholog: z3005; amino-acid ABC transporter ATP-binding protein YecC 2146490 yecC 1036960 yecC Escherichia coli CFT073 amino-acid ABC transporter ATP-binding protein YecC NP_754223.1 2145738 R 199310 CDS NP_754224.1 26248184 1036962 complement(2146487..2147155) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1918; Escherichia coli O157:H7 ortholog: z3006; amino-acid ABC transporter permease YecS 2147155 yecS 1036962 yecS Escherichia coli CFT073 amino-acid ABC transporter permease YecS NP_754224.1 2146487 R 199310 CDS NP_754225.1 26248185 1036963 complement(2147170..2148156) 1 NC_004431.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2148156 yedO 1036963 yedO Escherichia coli CFT073 D-cysteine desulfhydrase NP_754225.1 2147170 R 199310 CDS NP_754226.1 26248186 1036968 complement(2148324..2148833) 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 2148833 1036968 c2334 Escherichia coli CFT073 transposase NP_754226.1 2148324 R 199310 CDS NP_754227.1 26248187 1036969 complement(2148973..2149830) 1 NC_004431.1 CBP; Escherichia coli K-12 ortholog: b1920; Escherichia coli O157:H7 ortholog: z3010; cystine transporter subunit 2149830 fliY 1036969 fliY Escherichia coli CFT073 cystine transporter subunit NP_754227.1 2148973 R 199310 CDS NP_754228.1 26248188 1036971 complement(2149861..2150448) 1 NC_004431.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2150448 fliZ 1036971 fliZ Escherichia coli CFT073 flagella biosynthesis protein FliZ NP_754228.1 2149861 R 199310 CDS NP_754229.1 26248189 1036974 complement(2150458..2151177) 1 NC_004431.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2151177 fliA 1036974 fliA Escherichia coli CFT073 flagellar biosynthesis sigma factor NP_754229.1 2150458 R 199310 CDS NP_754230.1 26248190 1036977 complement(2151497..2153284) 1 NC_004431.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2153284 fliC 1036977 fliC Escherichia coli CFT073 flagellin NP_754230.1 2151497 R 199310 CDS NP_754231.1 26248191 1036978 2153550..2154956 1 NC_004431.1 involved in flagellin assembly; flagellar capping protein 2154956 fliD 1036978 fliD Escherichia coli CFT073 flagellar capping protein NP_754231.1 2153550 D 199310 CDS NP_754232.1 26248192 1036980 2154981..2155391 1 NC_004431.1 flagellin specific chaperone; flagellar protein FliS 2155391 fliS 1036980 fliS Escherichia coli CFT073 flagellar protein FliS NP_754232.1 2154981 D 199310 CDS NP_754233.1 26248193 1036983 2155391..2155756 1 NC_004431.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2155756 fliT 1036983 fliT Escherichia coli CFT073 flagellar biosynthesis protein FliT NP_754233.1 2155391 D 199310 CDS NP_754234.1 26248194 1036986 2155834..2157321 1 NC_004431.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2157321 amyA 1036986 amyA Escherichia coli CFT073 cytoplasmic alpha-amylase NP_754234.1 2155834 D 199310 CDS NP_754235.1 26248195 1036991 complement(2157355..2157771) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1928; Escherichia coli O157:H7 ortholog: z3018; hypothetical protein 2157771 yedD 1036991 yedD Escherichia coli CFT073 hypothetical protein NP_754235.1 2157355 R 199310 CDS NP_754236.1 26248196 1036994 2157922..2159160 1 NC_004431.1 Escherichia coli K-12 ortholog: b1929; Escherichia coli O157:H7 ortholog: z3019; inner membrane protein 2159160 yedE 1036994 yedE Escherichia coli CFT073 inner membrane protein NP_754236.1 2157922 D 199310 CDS NP_754237.1 26248197 1036997 2159157..2159390 1 NC_004431.1 Escherichia coli K-12 ortholog: b1930; Escherichia coli O157:H7 ortholog: z3020; hypothetical protein 2159390 yedF 1036997 yedF Escherichia coli CFT073 hypothetical protein NP_754237.1 2159157 D 199310 CDS NP_754238.1 26248198 1036998 2159499..2160167 1 NC_004431.1 Escherichia coli K-12 ortholog: b1931; Escherichia coli O157:H7 ortholog: z3021; hypothetical protein 2160167 yedK 1036998 yedK Escherichia coli CFT073 hypothetical protein NP_754238.1 2159499 D 199310 CDS NP_754239.1 26248199 1037000 2160619..2160765 1 NC_004431.1 hypothetical protein 2160765 1037000 c2347 Escherichia coli CFT073 hypothetical protein NP_754239.1 2160619 D 199310 CDS NP_754240.1 26248200 1037003 2160734..2161762 1 NC_004431.1 Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; outer membrane porin protein nmpC 2161762 1037003 c2348 Escherichia coli CFT073 outer membrane porin protein nmpC NP_754240.1 2160734 D 199310 CDS NP_754241.1 26248201 1037004 complement(2162264..2163061) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0546; transcriptional regulator YbcM 2163061 ybcM 1037004 ybcM Escherichia coli CFT073 transcriptional regulator YbcM NP_754241.1 2162264 R 199310 CDS NP_754242.1 26248202 1037005 complement(2163071..2163622) 1 NC_004431.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor 2163622 ybcL 1037005 ybcL Escherichia coli CFT073 kinase inhibitor NP_754242.1 2163071 R 199310 CDS NP_754243.1 26248203 1037010 2163238..2163360 1 NC_004431.1 hypothetical protein 2163360 1037010 c2351 Escherichia coli CFT073 hypothetical protein NP_754243.1 2163238 D 199310 CDS NP_754244.2 161486199 1037011 complement(2163791..2164123) 1 NC_004431.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 2164123 emrE 1037011 emrE Escherichia coli CFT073 multidrug efflux protein NP_754244.2 2163791 R 199310 CDS NP_754245.2 161486198 1037015 complement(2164468..2164782) 1 NC_004431.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2164782 fliE 1037015 fliE Escherichia coli CFT073 flagellar hook-basal body protein FliE NP_754245.2 2164468 R 199310 CDS NP_754246.1 26248206 1037017 2164997..2166655 1 NC_004431.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2166655 fliF 1037017 fliF Escherichia coli CFT073 flagellar MS-ring protein NP_754246.1 2164997 D 199310 CDS NP_754247.1 26248207 1037019 2166648..2167643 1 NC_004431.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2167643 fliG 1037019 fliG Escherichia coli CFT073 flagellar motor switch protein G NP_754247.1 2166648 D 199310 CDS NP_754248.1 26248208 1037021 complement(2166801..2167730) 1 NC_004431.1 hypothetical protein 2167730 1037021 c2356 Escherichia coli CFT073 hypothetical protein NP_754248.1 2166801 R 199310 CDS NP_754249.2 161486197 1037024 2167636..2168322 1 NC_004431.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2168322 fliH 1037024 fliH Escherichia coli CFT073 flagellar assembly protein H NP_754249.2 2167636 D 199310 CDS NP_754250.1 26248210 1037026 2168322..2169695 1 NC_004431.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2169695 fliI 1037026 fliI Escherichia coli CFT073 flagellum-specific ATP synthase NP_754250.1 2168322 D 199310 CDS NP_754251.1 26248211 1037027 2169714..2170157 1 NC_004431.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2170157 fliJ 1037027 fliJ Escherichia coli CFT073 flagellar biosynthesis chaperone NP_754251.1 2169714 D 199310 CDS NP_754252.1 26248212 1037033 2170154..2171281 1 NC_004431.1 Escherichia coli K-12 ortholog: b1943; Escherichia coli O157:H7 ortholog: z3033; flagellar hook-length control protein 2171281 fliK 1037033 fliK Escherichia coli CFT073 flagellar hook-length control protein NP_754252.1 2170154 D 199310 CDS NP_754253.1 26248213 1037035 2171386..2171850 1 NC_004431.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2171850 fliL 1037035 fliL Escherichia coli CFT073 flagellar basal body protein FliL NP_754253.1 2171386 D 199310 CDS NP_754254.1 26248214 1037037 2171810..2172859 1 NC_004431.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2172859 fliM 1037037 fliM Escherichia coli CFT073 flagellar motor switch protein FliM NP_754254.1 2171810 D 199310 CDS NP_754255.1 26248215 1037038 2172856..2173269 1 NC_004431.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2173269 fliN 1037038 fliN Escherichia coli CFT073 flagellar motor switch protein FliN NP_754255.1 2172856 D 199310 CDS NP_754256.1 26248216 1037039 2173269..2173637 1 NC_004431.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2173637 fliO 1037039 fliO Escherichia coli CFT073 flagellar biosynthesis protein FliO NP_754256.1 2173269 D 199310 CDS NP_754257.1 26248217 1037040 2173637..2174374 1 NC_004431.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2174374 fliP 1037040 fliP Escherichia coli CFT073 flagellar biosynthesis protein FliP NP_754257.1 2173637 D 199310 CDS NP_754258.1 26248218 1037041 2174384..2174653 1 NC_004431.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2174653 fliQ 1037041 fliQ Escherichia coli CFT073 flagellar biosynthesis protein FliQ NP_754258.1 2174384 D 199310 CDS NP_754259.1 26248219 1037042 2174662..2175447 1 NC_004431.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2175447 fliR 1037042 fliR Escherichia coli CFT073 flagellar biosynthesis protein FliR NP_754259.1 2174662 D 199310 CDS YP_004853813.1 347357933 1037046 2174685..2175083 1 NC_004431.1 hypothetical protein 2175083 1037046 c2368 Escherichia coli CFT073 hypothetical protein YP_004853813.1 2174685 D 199310 CDS NP_754261.1 26248221 1037047 2175737..2176360 1 NC_004431.1 Escherichia coli K-12 ortholog: b1951; Escherichia coli O157:H7 ortholog: z3041; colanic acid capsular biosynthesis activation protein A 2176360 rcsA 1037047 rcsA Escherichia coli CFT073 colanic acid capsular biosynthesis activation protein A NP_754261.1 2175737 D 199310 CDS NP_754262.1 26248222 1037048 complement(2176404..2176592) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1952; Escherichia coli O157:H7 ortholog: z3042; hypothetical protein 2176592 dsrB 1037048 dsrB Escherichia coli CFT073 hypothetical protein NP_754262.1 2176404 R 199310 CDS NP_754263.1 26248223 1037049 complement(2176689..2176952) 1 NC_004431.1 hypothetical protein 2176952 1037049 c2371 Escherichia coli CFT073 hypothetical protein NP_754263.1 2176689 R 199310 CDS NP_754264.1 26248224 1037051 2176740..2176982 1 NC_004431.1 Escherichia coli K-12 ortholog: b1953; Escherichia coli O157:H7 ortholog: z3043; hypothetical protein 2176982 yodD 1037051 yodD Escherichia coli CFT073 hypothetical protein NP_754264.1 2176740 D 199310 CDS NP_754265.1 26248225 1037052 2177280..2178095 1 NC_004431.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2178095 yedP 1037052 yedP Escherichia coli CFT073 mannosyl-3-phosphoglycerate phosphatase NP_754265.1 2177280 D 199310 CDS NP_754266.1 26248226 1037057 complement(2178092..2179801) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1956; Escherichia coli O157:H7 ortholog: z3047; hypothetical protein 2179801 yedQ 1037057 yedQ Escherichia coli CFT073 hypothetical protein NP_754266.1 2178092 R 199310 CDS NP_754267.1 26248227 1037059 complement(2179707..2179895) 1 NC_004431.1 hypothetical protein 2179895 1037059 c2375 Escherichia coli CFT073 hypothetical protein NP_754267.1 2179707 R 199310 CDS NP_754268.1 26248228 1037061 complement(2179957..2180139) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1957; Escherichia coli O157:H7 ortholog: z3048; hypothetical protein 2180139 yodC 1037061 yodC Escherichia coli CFT073 hypothetical protein NP_754268.1 2179957 R 199310 CDS NP_754269.1 26248229 1037063 complement(2180218..2181135) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1958; Escherichia coli O157:H7 ortholog: z3049; hypothetical protein 2181135 yedI 1037063 yedI Escherichia coli CFT073 hypothetical protein NP_754269.1 2180218 R 199310 CDS NP_754270.1 26248230 1037080 2181308..2182228 1 NC_004431.1 Escherichia coli K-12 ortholog: b1959; Escherichia coli O157:H7 ortholog: z3050; hypothetical protein 2182228 yedA 1037080 yedA Escherichia coli CFT073 hypothetical protein NP_754270.1 2181308 D 199310 CDS NP_754271.1 26248231 1037084 complement(2182217..2182687) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1960; Escherichia coli O157:H7 ortholog: z3053; very short patch repair protein 2182687 vsr 1037084 vsr Escherichia coli CFT073 very short patch repair protein NP_754271.1 2182217 R 199310 CDS NP_754272.1 26248232 1037085 complement(2182668..2184086) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1961; Escherichia coli O157:H7 ortholog: z3054; DNA cytosine methylase 2184086 dcm 1037085 dcm Escherichia coli CFT073 DNA cytosine methylase NP_754272.1 2182668 R 199310 CDS NP_754273.1 26248233 1037099 complement(2184198..2184875) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1962; Escherichia coli O157:H7 ortholog: z3055; hypothetical protein 2184875 yedJ 1037099 yedJ Escherichia coli CFT073 hypothetical protein NP_754273.1 2184198 R 199310 CDS NP_754274.1 26248234 1037109 complement(2184888..2185271) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1963; Escherichia coli O157:H7 ortholog: z3056; hypothetical protein 2185271 yedR 1037109 yedR Escherichia coli CFT073 hypothetical protein NP_754274.1 2184888 R 199310 CDS NP_754275.1 26248235 1037128 2185750..2186877 1 NC_004431.1 Porin ompN; Escherichia coli K-12 ortholog: b1377; Escherichia coli O157:H7 ortholog: z0302; outer membrane protein N 2186877 1037128 c2383 Escherichia coli CFT073 outer membrane protein N NP_754275.1 2185750 D 199310 CDS YP_004853814.1 347357934 1037137 2186327..2186551 1 NC_004431.1 hypothetical protein 2186551 1037137 c2384 Escherichia coli CFT073 hypothetical protein YP_004853814.1 2186327 D 199310 CDS NP_754277.1 26248237 1037145 2187473..2188324 1 NC_004431.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2188324 yedU 1037145 yedU Escherichia coli CFT073 chaperone protein HchA NP_754277.1 2187473 D 199310 CDS NP_754278.1 26248238 1037165 complement(2188432..2189790) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1968; Escherichia coli O157:H7 ortholog: z3060; sensor-like histidine kinase yedV 2189790 yedV 1037165 yedV Escherichia coli CFT073 sensor-like histidine kinase yedV NP_754278.1 2188432 R 199310 CDS NP_754279.2 161486196 1037181 complement(2189790..2190461) 1 NC_004431.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2190461 yedW 1037181 yedW Escherichia coli CFT073 transcriptional regulatory protein YedW NP_754279.2 2189790 R 199310 CDS NP_754280.1 26248240 1037211 2190594..2191007 1 NC_004431.1 Escherichia coli K-12 ortholog: b1970; Escherichia coli O157:H7 ortholog: z3062; transthyretin-like protein 2191007 1037211 c2388 Escherichia coli CFT073 transthyretin-like protein NP_754280.1 2190594 D 199310 CDS NP_754281.1 26248241 1037215 2191116..2192120 1 NC_004431.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2192120 yedY 1037215 yedY Escherichia coli CFT073 sulfite oxidase subunit YedY NP_754281.1 2191116 D 199310 CDS NP_754282.1 26248242 1037234 2192121..2192756 1 NC_004431.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2192756 yedZ 1037234 yedZ Escherichia coli CFT073 sulfite oxidase subunit YedZ NP_754282.1 2192121 D 199310 CDS NP_754283.1 26248243 1037244 2193014..2193646 1 NC_004431.1 Escherichia coli K-12 ortholog: b1973; Escherichia coli O157:H7 ortholog: z3065; hypothetical protein 2193646 yodA 1037244 yodA Escherichia coli CFT073 hypothetical protein NP_754283.1 2193014 D 199310 CDS NP_754284.1 26248244 1037246 2194512..2195732 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1559; P4 family integrase 2195732 1037246 c2392 Escherichia coli CFT073 P4 family integrase NP_754284.1 2194512 D 199310 CDS NP_754285.1 26248245 1037266 2195846..2197666 1 NC_004431.1 Residues 9 to 606 of 606 are 31.75 pct identical to residues 13 to 622 of 624 from GenPept.129 : >gb|AAL21647.1| (AE008825) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 2197666 1037266 c2393 Escherichia coli CFT073 hypothetical protein NP_754285.1 2195846 D 199310 CDS NP_754286.1 26248246 1037274 complement(2197781..2199244) 1 NC_004431.1 Residues 5 to 407 of 487 are 26.82 pct identical to residues 6 to 347 of 417 from GenPept.129 : >dbj|BAB12639.1| (AP002527) 100 pct identical to gp:ECINCI2_2[PilV of plasmid R721]; 48 pct identical(7 gaps) to397 residues of 474 aa protein gp:D88588_18[PilV of plasmid R64] [Escherichia coli]; PilV-like protein 2199244 1037274 c2394 Escherichia coli CFT073 PilV-like protein NP_754286.1 2197781 R 199310 CDS NP_754287.1 26248247 1037284 complement(2199297..2199854) 1 NC_004431.1 Residues 7 to 184 of 185 are 27.37 pct identical to residues 21 to 183 of 185 from GenPept.129 : >dbj|BAB12642.1| (AP002527) 30 pct identical(11 gaps) to gp:D88588_15[PilS of plasmid R64] [Escherichia coli]; type IV pilin protein 2199854 1037284 c2395 Escherichia coli CFT073 type IV pilin protein NP_754287.1 2199297 R 199310 CDS NP_754288.1 26248248 1037285 complement(2200253..2200567) 1 NC_004431.1 hypothetical protein 2200567 1037285 c2396 Escherichia coli CFT073 hypothetical protein NP_754288.1 2200253 R 199310 CDS NP_754289.1 26248249 1037286 2201204..2202706 1 NC_004431.1 Residues 1 to 201 of 500 are 45.77 pct identical to residues 1 to 200 of 714 from GenPept.129 : >gb|AAK13432.1| (AF322908) repB/MobA-like protein [Xylella fastidiosa]; hypothetical protein 2202706 1037286 c2397 Escherichia coli CFT073 hypothetical protein NP_754289.1 2201204 D 199310 CDS NP_754290.1 26248250 1037287 2202763..2203686 1 NC_004431.1 Residues 171 to 299 of 307 are 55.03 pct identical to residues 119 to 246 of 250 from GenPept.129 : >gb|AAL52855.1| (AE009602) Hypothetical Protein [Brucella melitensis]; hypothetical protein 2203686 1037287 c2398 Escherichia coli CFT073 hypothetical protein NP_754290.1 2202763 D 199310 CDS NP_754291.1 26248251 1037289 complement(2203818..2204327) 1 NC_004431.1 Residues 1 to 108 of 169 are 35.19 pct identical to residues 1 to 119 of 186 from GenPept.129 : >dbj|BAB73899.1| (AP003588) ORF_ID:all2200; unknown protein [Nostoc sp. PCC 7120]; hypothetical protein 2204327 1037289 c2399 Escherichia coli CFT073 hypothetical protein NP_754291.1 2203818 R 199310 CDS NP_754292.1 26248252 1037295 2204464..2205300 1 NC_004431.1 Residues 1 to 278 of 278 are 66.18 pct identical to residues 5 to 282 of 282 from GenPept.129 : >emb|CAD16319.1| (AL646071) HYPOTHETICAL TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]; hypothetical protein 2205300 1037295 c2400 Escherichia coli CFT073 hypothetical protein NP_754292.1 2204464 D 199310 CDS NP_754293.1 26248253 1037296 complement(2205646..2206221) 1 NC_004431.1 hypothetical protein 2206221 1037296 c2401 Escherichia coli CFT073 hypothetical protein NP_754293.1 2205646 R 199310 CDS NP_754294.1 26248254 1037297 complement(2206262..2206399) 1 NC_004431.1 hypothetical protein 2206399 1037297 c2402 Escherichia coli CFT073 hypothetical protein NP_754294.1 2206262 R 199310 CDS NP_754295.1 26248255 1037298 2206594..2207082 1 NC_004431.1 hypothetical protein 2207082 1037298 c2403 Escherichia coli CFT073 hypothetical protein NP_754295.1 2206594 D 199310 CDS NP_754296.1 26248256 1037300 2207072..2207284 1 NC_004431.1 Residues 23 to 67 of 70 are 57.77 pct identical to residues 16 to 60 of 131 from GenPept.129 : >dbj|BAB36929.1| (AP002562) hypothetical lipoprotein [Escherichia coli O157:H7]; hypothetical protein 2207284 1037300 c2404 Escherichia coli CFT073 hypothetical protein NP_754296.1 2207072 D 199310 CDS NP_754297.1 26248257 1037301 complement(2207572..2208753) 1 NC_004431.1 hypothetical protein 2208753 1037301 c2405 Escherichia coli CFT073 hypothetical protein NP_754297.1 2207572 R 199310 CDS NP_754298.1 26248258 1037304 complement(2208805..2209767) 1 NC_004431.1 hypothetical protein 2209767 1037304 c2406 Escherichia coli CFT073 hypothetical protein NP_754298.1 2208805 R 199310 CDS NP_754299.1 26248259 1037305 2210085..2210237 1 NC_004431.1 hypothetical protein 2210237 1037305 c2407 Escherichia coli CFT073 hypothetical protein NP_754299.1 2210085 D 199310 CDS NP_754300.1 26248260 1037306 2211120..2211701 1 NC_004431.1 Residues 11 to 168 of 193 are 33.33 pct identical to residues 8 to 171 of 193 from GenPept.129 : >dbj|BAA92822.1| (AB022096) replication protein [Pseudoalteromonas sp. PS1M3]; hypothetical protein 2211701 1037306 c2408 Escherichia coli CFT073 hypothetical protein NP_754300.1 2211120 D 199310 CDS NP_754301.1 26248261 1037307 complement(2211786..2212517) 1 NC_004431.1 hypothetical protein 2212517 1037307 c2409 Escherichia coli CFT073 hypothetical protein NP_754301.1 2211786 R 199310 CDS NP_754302.1 26248262 1037309 2212691..2213170 1 NC_004431.1 hypothetical protein 2213170 1037309 c2410 Escherichia coli CFT073 hypothetical protein NP_754302.1 2212691 D 199310 CDS NP_754303.1 26248263 1037311 2213329..2213733 1 NC_004431.1 Histone-like protein HLP-II; Escherichia coli K-12 ortholog: b1237; Escherichia coli O157:H7 ortholog: z2013; DNA-binding protein H-NS 2213733 1037311 c2411 Escherichia coli CFT073 DNA-binding protein H-NS NP_754303.1 2213329 D 199310 CDS NP_754304.1 26248264 1037314 complement(2213797..2214177) 1 NC_004431.1 Residues 24 to 125 of 126 are 52.94 pct identical to residues 1 to 102 of 102 from GenPept.129 : >gb|AAA23184.1| (M13819) unknown [Plasmid ColIa]; hypothetical protein 2214177 1037314 c2412 Escherichia coli CFT073 hypothetical protein NP_754304.1 2213797 R 199310 CDS NP_754305.1 26248265 1037315 complement(2214256..2214498) 1 NC_004431.1 hypothetical protein 2214498 1037315 c2413 Escherichia coli CFT073 hypothetical protein NP_754305.1 2214256 R 199310 CDS NP_754306.1 26248266 1037317 complement(2214571..2214867) 1 NC_004431.1 hypothetical protein 2214867 1037317 c2414 Escherichia coli CFT073 hypothetical protein NP_754306.1 2214571 R 199310 CDS NP_754307.1 26248267 1037321 complement(2214920..2215222) 1 NC_004431.1 hypothetical protein 2215222 1037321 c2415 Escherichia coli CFT073 hypothetical protein NP_754307.1 2214920 R 199310 CDS NP_754308.1 26248268 1037322 complement(2215727..2216620) 1 NC_004431.1 Residues 24 to 281 of 297 are 26.97 pct identical to residues 7 to 269 of 283 from GenPept.129 : >gb|AAG57759.1|AE005493_12 (AE005493) Z3947 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 2216620 1037322 c2416 Escherichia coli CFT073 hypothetical protein NP_754308.1 2215727 R 199310 CDS NP_754309.1 26248269 1037325 2216985..2217821 1 NC_004431.1 Escherichia coli K-12 ortholog: b1976; Escherichia coli O157:H7 ortholog: z3132; hypothetical protein 2217821 yeeI 1037325 yeeI Escherichia coli CFT073 hypothetical protein NP_754309.1 2216985 D 199310 CDS NP_754310.1 26248270 1037330 2218378..2219421 1 NC_004431.1 Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 2219421 1037330 c2418 Escherichia coli CFT073 prophage P4 integrase NP_754310.1 2218378 D 199310 CDS NP_754311.1 26248271 1037332 complement(2219615..2220919) 1 NC_004431.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 2220919 1037332 c2419 Escherichia coli CFT073 salicylate synthase Irp9 NP_754311.1 2219615 R 199310 CDS NP_754312.1 26248272 1037333 complement(2220947..2222350) 1 NC_004431.1 Similar to YbtX [Yersinia pestis] and Irp8 [Yersinia enterocolitica]; Residues 6 to 467 of 467 are 99.35 pct identical to residues 1 to 462 of 462 from GenPept.129 : >emb|CAA21386.1| (AL031866) ORF63,len=462 aa, transmembrane protein, similarity to Escherichia coli ECAMPG3_1 E.coli ampG3 gene, 27.1% identity in 376 aa overlap, Fasta scores: opt: 311, E(): 1.1e-12 [Yersinia pestis]; cytoplasmic transmembrane protein 2222350 1037333 c2420 Escherichia coli CFT073 cytoplasmic transmembrane protein NP_754312.1 2220947 R 199310 CDS NP_754313.1 26248273 1037334 complement(2222220..2224049) 1 NC_004431.1 Similar to YbtQ [Yersinia pestis] and Irp7 [Yersinia enterocolitica]; Residues 10 to 609 of 609 are 99.50 pct identical to residues 1 to 600 of 600 from GenPept.129 : >emb|CAC90730.1| (AJ414150) inner membrane ABC-transporter YbtQ [Yersinia pestis]; ABC transporter 2224049 1037334 c2421 Escherichia coli CFT073 ABC transporter NP_754313.1 2222220 R 199310 CDS NP_754314.1 26248274 1037336 complement(2224009..2225811) 1 NC_004431.1 Similar to YbtP [Yersinia pestis] and Irp6 [Yersinia enterocolitica]; Residues 1 to 600 of 600 are 100.00 pct identical to residues 1 to 600 of 600 from GenPept.129 : >gb|AAC69585.1| (AF091251) YbtP [Yersinia pestis]; inner membrane ABC-transporter 2225811 1037336 c2422 Escherichia coli CFT073 inner membrane ABC-transporter NP_754314.1 2224009 R 199310 CDS NP_754315.1 26248275 1037338 2225978..2226937 1 NC_004431.1 Similar to YbtA, AraC type regulator [Yersinia pestis]; Residues 1 to 319 of 319 are 99.37 pct identical to residues 1 to 319 of 319 from GenPept.129 : >emb|CAC90728.1| (AJ414150) transcriptional regulator YbtA [Yersinia pestis]; AraC type regulator 2226937 1037338 c2423 Escherichia coli CFT073 AraC type regulator NP_754315.1 2225978 D 199310 CDS NP_754316.1 26248276 1037339 2227110..2231378 1 NC_004431.1 Similar to middle of Ybt peptide synthetase HMWP2 [Yersinia pestis]; Residues 7 to 1418 of 1422 are 98.22 pct identical to residues 1 to 1412 of 2035 from SwissProt.40 : >sp|P48633|HMP2_YEREN High-molecular-weight protein 2 (HMWP2); peptide synthetase 2231378 1037339 c2424 Escherichia coli CFT073 peptide synthetase NP_754316.1 2227110 D 199310 CDS NP_754317.1 26248277 1037341 complement(2231467..2231844) 1 NC_004431.1 Residues 2 to 125 of 125 are 93.54 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 2231844 1037341 c2425 Escherichia coli CFT073 hypothetical protein NP_754317.1 2231467 R 199310 CDS NP_754318.1 26248278 1037342 2231817..2233946 1 NC_004431.1 Similar to C-terminus of Ybt peptide synthetase HMWP2 [Yersinia pestis]; Residues 95 to 597 of 709 are 35.05 pct identical to residues 34 to 551 of 2035 from GenPept.129 : >emb|CAC90727.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; peptide synthetase 2233946 1037342 c2426 Escherichia coli CFT073 peptide synthetase NP_754318.1 2231817 D 199310 CDS NP_754319.1 26248279 1037343 2234022..2236217 1 NC_004431.1 Similar to the N-terminus of the synthetase for the yersiniabactin siderophore [Yersinia enterocolitica]; Residues 5 to 721 of 731 are 99.72 pct identical to residues 1 to 717 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; peptide/polyketide synthetase protein 2236217 1037343 c2427 Escherichia coli CFT073 peptide/polyketide synthetase protein NP_754319.1 2234022 D 199310 CDS NP_754320.1 26248280 1037345 2236117..2239014 1 NC_004431.1 Residues 276 to 576 of 965 are 29.73 pct identical to residues 2481 to 2770 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; hypothetical protein 2239014 1037345 c2428 Escherichia coli CFT073 hypothetical protein NP_754320.1 2236117 D 199310 CDS NP_754321.1 26248281 1037348 2238812..2243521 1 NC_004431.1 Residues 887 to 1176 of 1569 are 29.73 pct identical to residues 970 to 1270 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; hypothetical protein 2243521 1037348 c2429 Escherichia coli CFT073 hypothetical protein NP_754321.1 2238812 D 199310 CDS NP_754322.1 26248282 1037349 2243518..2244618 1 NC_004431.1 Residues 1 to 366 of 366 are 99.72 pct identical to residues 1 to 366 of 366 from GenPept.129 : >emb|CAC90725.1| (AJ414150) yersiniabactin biosynthetic protein YbtU [Yersinia pestis]; hypothetical protein 2244618 1037349 c2430 Escherichia coli CFT073 hypothetical protein NP_754322.1 2243518 D 199310 CDS NP_754323.1 26248283 1037381 complement(2244588..2244722) 1 NC_004431.1 hypothetical protein 2244722 1037381 c2431 Escherichia coli CFT073 hypothetical protein NP_754323.1 2244588 R 199310 CDS NP_754324.1 26248284 1037387 2244762..2245418 1 NC_004431.1 Similar to YbtT [Yersinia pestis]; Residues 1 to 187 of 218 are 40.95 pct identical to residues 48 to 235 of 252 from SwissProt.40 : >sp|P19829|SAST_VIBAN Probable anguibactin biosynthesis thioesterase; thioesterase 2245418 1037387 c2432 Escherichia coli CFT073 thioesterase NP_754324.1 2244762 D 199310 CDS NP_754325.1 26248285 1037388 2245422..2246669 1 NC_004431.1 Enterochelin synthase E; Escherichia coli K-12 ortholog: b0594; Escherichia coli O157:H7 ortholog: z0736; bifunctional; Enterobactin synthetase component E; S-dihydroxybenzoyltransferase; 2,3-dihydroxybenzoate-AMP ligase 2246669 1037388 c2433 Escherichia coli CFT073 2,3-dihydroxybenzoate-AMP ligase NP_754325.1 2245422 D 199310 CDS NP_754326.1 26248286 1037395 2246714..2246998 1 NC_004431.1 Similar to ligase YbtE [Yersinia pestis]; Residues 1 to 94 of 94 are 98.93 pct identical to residues 432 to 525 of 525 from GenPept.129 : >emb|CAC90723.1| (AJ414150) yersiniabactin siderophore biosynthetic protein [Yersinia pestis]; salicyl-AMP ligase 2246998 1037395 c2434 Escherichia coli CFT073 salicyl-AMP ligase NP_754326.1 2246714 D 199310 CDS NP_754327.1 26248287 1037401 complement(2246735..2247004) 1 NC_004431.1 hypothetical protein 2247004 1037401 c2435 Escherichia coli CFT073 hypothetical protein NP_754327.1 2246735 R 199310 CDS NP_754328.1 26248288 1037428 2247129..2249150 1 NC_004431.1 Similar to FyuA precursor [Yersinia pestis]; Residues 1 to 673 of 673 are 99.85 pct identical to residues 1 to 673 of 673 from SwissProt.40 : >sp|P46359|FYUA_YERPE Pesticin receptor precursor (IRPC); pesticin receptor 2249150 1037428 c2436 Escherichia coli CFT073 pesticin receptor NP_754328.1 2247129 D 199310 CDS NP_754329.1 26248289 1037431 2249741..2250547 1 NC_004431.1 Residues 14 to 136 of 268 are 98.37 pct identical to residues 2 to 124 of 128 from GenPept.129 : >gb|AAC69596.1| (AF091251) unknown [Yersinia pestis]; hypothetical protein 2250547 1037431 c2437 Escherichia coli CFT073 hypothetical protein NP_754329.1 2249741 D 199310 CDS NP_754330.1 26248290 1037434 2250474..2250644 1 NC_004431.1 Residues 1 to 47 of 56 are 93.61 pct identical to residues 1459 to 1505 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2250644 1037434 c2438 Escherichia coli CFT073 hypothetical protein NP_754330.1 2250474 D 199310 CDS NP_754331.1 26248291 1037449 2250680..2252149 1 NC_004431.1 Residues 35 to 487 of 489 are 26.20 pct identical to residues 531 to 997 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2252149 1037449 c2439 Escherichia coli CFT073 hypothetical protein NP_754331.1 2250680 D 199310 CDS NP_754332.1 26248292 1037467 2252162..2252638 1 NC_004431.1 Residues 1 to 148 of 158 are 82.43 pct identical to residues 2127 to 2273 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2252638 1037467 c2440 Escherichia coli CFT073 hypothetical protein NP_754332.1 2252162 D 199310 CDS NP_754333.1 26248293 1037496 complement(2252766..2253386) 1 NC_004431.1 Residues 1 to 206 of 206 are 95.14 pct identical to residues 145 to 350 of 350 from GenPept.129 : >dbj|BAB36200.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 2253386 1037496 c2441 Escherichia coli CFT073 hypothetical protein NP_754333.1 2252766 R 199310 CDS NP_754334.1 26248294 1037534 complement(2253361..2253879) 1 NC_004431.1 Residues 22 to 157 of 172 are 98.52 pct identical to residues 1 to 136 of 350 from GenPept.129 : >gb|AAG57043.1|AE005424_1 (AE005424) Z3137 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 2253879 1037534 c2442 Escherichia coli CFT073 hypothetical protein NP_754334.1 2253361 R 199310 CDS NP_754335.1 26248295 1037558 2254131..2255447 1 NC_004431.1 Escherichia coli K-12 ortholog: b1981; Escherichia coli O157:H7 ortholog: z3138; shikimate transporter 2255447 shiA 1037558 shiA Escherichia coli CFT073 shikimate transporter NP_754335.1 2254131 D 199310 CDS NP_754336.2 161486195 1037571 2255549..2257003 1 NC_004431.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2257003 amn 1037571 amn Escherichia coli CFT073 AMP nucleosidase NP_754336.2 2255549 D 199310 CDS NP_754337.1 26248297 1037574 2257346..2258062 1 NC_004431.1 Escherichia coli K-12 ortholog: b1983; Escherichia coli O157:H7 ortholog: z3140; hypothetical protein 2258062 yeeN 1037574 yeeN Escherichia coli CFT073 hypothetical protein NP_754337.1 2257346 D 199310 CDS NP_754338.2 161486194 1037586 2258918..2259835 1 NC_004431.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2259835 nac 1037586 nac Escherichia coli CFT073 nitrogen assimilation transcriptional regulator NP_754338.2 2258918 D 199310 CDS NP_754339.1 26248299 1037592 2259937..2260887 1 NC_004431.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2260887 cbl 1037592 cbl Escherichia coli CFT073 transcriptional regulator Cbl NP_754339.1 2259937 D 199310 CDS NP_754340.1 26248300 1037627 2261008..2262648 1 NC_004431.1 Escherichia coli K-12 ortholog: b1985; Escherichia coli O157:H7 ortholog: z3144; hypothetical protein 2262648 yeeO 1037627 yeeO Escherichia coli CFT073 hypothetical protein NP_754340.1 2261008 D 199310 CDS NP_754341.1 26248301 1037632 2262986..2264257 1 NC_004431.1 Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 2264257 1037632 c2449 Escherichia coli CFT073 prophage P4 integrase NP_754341.1 2262986 D 199310 CDS NP_754342.1 26248302 1037633 complement(2264537..2265049) 1 NC_004431.1 Residues 1 to 166 of 170 are 53.61 pct identical to residues 1 to 165 of 172 from GenPept.129 : >gb|AAF60966.1|AF188737_1 (AF188737) unknown [Escherichia coli]; hypothetical protein 2265049 1037633 c2450 Escherichia coli CFT073 hypothetical protein NP_754342.1 2264537 R 199310 CDS NP_754343.1 26248303 1037635 complement(2265084..2265806) 1 NC_004431.1 Residues 4 to 233 of 240 are 33.91 pct identical to residues 1 to 228 of 234 from GenPept.129 : >gb|AAD21211.1| (AF007865) BacT [Bacillus licheniformis]; thioesterase 2265806 1037635 c2451 Escherichia coli CFT073 thioesterase NP_754343.1 2265084 R 199310 CDS NP_754344.1 26248304 1037636 complement(2265799..2267313) 1 NC_004431.1 Residues 41 to 499 of 504 are 27.77 pct identical to residues 41 to 494 of 498 from GenPept.129 : >dbj|BAB58603.1| (AP003365) hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]; hypothetical protein 2267313 1037636 c2452 Escherichia coli CFT073 hypothetical protein NP_754344.1 2265799 R 199310 CDS NP_754345.1 26248305 1037638 complement(2267326..2269785) 1 NC_004431.1 polyketide synthase; Residues 13 to 647 of 819 are 36.74 pct identical to residues 1458 to 2126 of 3291 from GenPept.129 : >gb|AAF19812.1|AF188287_4 (AF188287) MtaD [Stigmatella aurantiaca]; polyketide synthase 2269785 1037638 c2453 Escherichia coli CFT073 polyketide synthase NP_754345.1 2267326 R 199310 CDS NP_754346.1 26248306 1037644 complement(2269816..2270931) 1 NC_004431.1 Residues 47 to 278 of 371 are 30.20 pct identical to residues 1809 to 2049 of 2157 from GenPept.129 : >gb|AAL44495.1| (AE009298) peptide synthetase [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 2270931 1037644 c2454 Escherichia coli CFT073 hypothetical protein NP_754346.1 2269816 R 199310 CDS NP_754347.1 26248307 1037646 complement(2270909..2274271) 1 NC_004431.1 peptide synthetase; Residues 35 to 363 of 1120 are 22.25 pct identical to residues 4932 to 5253 of 5369 from GenPept.129 : >gb|AAF08796.1|AF184956_3 (AF184956) MycB [Bacillus subtilis]; peptide synthetase 2274271 1037646 c2455 Escherichia coli CFT073 peptide synthetase NP_754347.1 2270909 R 199310 CDS NP_754348.1 26248308 1037656 complement(2274181..2275620) 1 NC_004431.1 Residues 26 to 457 of 479 are 29.47 pct identical to residues 14 to 449 of 461 from GenPept.129 : >gb|AAL80832.1| (AE010190) hypothetical protein [Pyrococcus furiosus DSM 3638]; hypothetical protein 2275620 1037656 c2456 Escherichia coli CFT073 hypothetical protein NP_754348.1 2274181 R 199310 CDS NP_754349.1 26248309 1037661 complement(2275682..2277169) 1 NC_004431.1 Residues 17 to 492 of 495 are 35.31 pct identical to residues 12 to 484 of 507 from GenPept.129 : >gb|AAG30199.1| (AF293442) enantiomer selective amidase [Streptomyces sp. R1128]; amidase 2277169 1037661 c2457 Escherichia coli CFT073 amidase NP_754349.1 2275682 R 199310 CDS NP_754350.1 26248310 1037664 complement(2277138..2283602) 1 NC_004431.1 Residues 1988 to 2110 of 2154 are 33.33 pct identical to residues 947 to 1067 of 2459 from GenPept.129 : >dbj|BAB74344.1| (AP003590) peptide synthetase [Nostoc sp. PCC 7120]; peptide synthetase 2283602 1037664 c2458 Escherichia coli CFT073 peptide synthetase NP_754350.1 2277138 R 199310 CDS NP_754351.1 26248311 1037665 complement(2283613..2290113) 1 NC_004431.1 Residues 1998 to 2132 of 2166 are 30.37 pct identical to residues 2271 to 2401 of 2459 from GenPept.129 : >dbj|BAB74344.1| (AP003590) peptide synthetase [Nostoc sp. PCC 7120]; peptide synthetase 2290113 1037665 c2459 Escherichia coli CFT073 peptide synthetase NP_754351.1 2283613 R 199310 CDS NP_754352.1 26248312 1037666 complement(2290157..2293189) 1 NC_004431.1 Residues 4 to 882 of 1010 are 46.58 pct identical to residues 8 to 898 of 1244 from GenPept.129 : >gb|AAF15892.2|AF204805_2 (AF204805) NosB [Nostoc sp. GSV224]; polyketide synthase 2293189 1037666 c2460 Escherichia coli CFT073 polyketide synthase NP_754352.1 2290157 R 199310 CDS NP_754353.1 26248313 1037668 complement(2293239..2298050) 1 NC_004431.1 Residues 46 to 514 of 1603 are 34.82 pct identical to residues 2731 to 3210 of 3317 from GenPept.129 : >gb|AAF17280.1| (AF204805) NosC [Nostoc sp. GSV224]; hypothetical protein 2298050 1037668 c2461 Escherichia coli CFT073 hypothetical protein NP_754353.1 2293239 R 199310 CDS NP_754354.1 26248314 1037673 2295405..2295536 1 NC_004431.1 hypothetical protein 2295536 1037673 c2462 Escherichia coli CFT073 hypothetical protein NP_754354.1 2295405 D 199310 CDS NP_754355.1 26248315 1037674 complement(2298083..2299351) 1 NC_004431.1 Residues 4 to 392 of 422 are 29.30 pct identical to residues 3 to 374 of 400 from GenPept.129 : >dbj|BAB69697.1| (AB050629) malonyl-CoA transacylase [Bacillus subtilis]; transacylase 2299351 1037674 c2463 Escherichia coli CFT073 transacylase NP_754355.1 2298083 R 199310 CDS NP_754356.1 26248316 1037678 complement(2299348..2300376) 1 NC_004431.1 Residues 3 to 335 of 342 are 35.02 pct identical to residues 35 to 368 of 382 from GenPept.129 : >gb|AAD40109.1|AF155831_3 (AF155831) unknown [Bacillus cereus]; acyl-coa dehydrogenase 2300376 1037678 c2464 Escherichia coli CFT073 acyl-coa dehydrogenase NP_754356.1 2299348 R 199310 CDS NP_754357.1 26248317 1037692 2300422..2300619 1 NC_004431.1 hypothetical protein 2300619 1037692 c2465 Escherichia coli CFT073 hypothetical protein NP_754357.1 2300422 D 199310 CDS NP_754358.1 26248318 1037695 complement(2300482..2300730) 1 NC_004431.1 Residues 1 to 78 of 82 are 30.76 pct identical to residues 1 to 77 of 81 from GenPept.129 : >gb|AAL32271.1| (AF235003) D-alanyl carrier protein [Bacillus thuringiensis serovar kurstaki]; hypothetical protein 2300730 1037695 c2466 Escherichia coli CFT073 hypothetical protein NP_754358.1 2300482 R 199310 CDS NP_754359.1 26248319 1037697 complement(2300760..2301629) 1 NC_004431.1 Residues 2 to 282 of 289 are 45.55 pct identical to residues 1 to 278 of 278 from SwissProt.40 : >sp|Q9RVG1|HBD_DEIRA Probable 3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD); 3-hydroxyacyl-CoA dehydrogenase 2301629 1037697 c2467 Escherichia coli CFT073 3-hydroxyacyl-CoA dehydrogenase NP_754359.1 2300760 R 199310 CDS NP_754360.1 26248320 1037698 complement(2301639..2304248) 1 NC_004431.1 Residues 15 to 504 of 869 are 46.97 pct identical to residues 1458 to 1953 of 3291 from GenPept.129 : >gb|AAF19812.1|AF188287_4 (AF188287) MtaD [Stigmatella aurantiaca]; polyketide synthase 2304248 1037698 c2468 Escherichia coli CFT073 polyketide synthase NP_754360.1 2301639 R 199310 CDS NP_754361.1 26248321 1037706 complement(2304280..2308338) 1 NC_004431.1 Residues 34 to 562 of 1352 are 24.60 pct identical to residues 2344 to 2882 of 7257 from GenPept.129 : >gb|AAF62883.1|AF217189_6 (AF217189) epoD [Polyangium cellulosum]; polyketide synthase 2308338 1037706 c2469 Escherichia coli CFT073 polyketide synthase NP_754361.1 2304280 R 199310 CDS NP_754362.1 26248322 1037707 complement(2308283..2313910) 1 NC_004431.1 Residues 527 to 1874 of 1875 are 32.28 pct identical to residues 47 to 1483 of 2632 from GenPept.129 : >dbj|BAB12213.1| (AB032549) peptide synthetase and polyketide synthase [Microcystis aeruginosa]; peptide/polyketide synthase 2313910 1037707 c2470 Escherichia coli CFT073 peptide/polyketide synthase NP_754362.1 2308283 R 199310 CDS NP_754363.1 26248323 1037708 2314524..2315258 1 NC_004431.1 Residues 22 to 171 of 244 are 38.41 pct identical to residues 32 to 178 of 249 from GenPept.129 : >gb|AAD10395.1| (U46488) NrpG [Proteus mirabilis]; hypothetical protein 2315258 1037708 c2471 Escherichia coli CFT073 hypothetical protein NP_754363.1 2314524 D 199310 CDS NP_754364.1 26248324 1037712 2315404..2315670 1 NC_004431.1 Residues 1 to 88 of 88 are 71.59 pct identical to residues 1 to 88 of 88 from SwissProt.40 : >sp|Q00931|LCRS_YERPE Low calcium response locus protein S; transposase 2315670 1037712 c2472 Escherichia coli CFT073 transposase NP_754364.1 2315404 D 199310 CDS NP_754365.1 26248325 1037713 2315775..2316254 1 NC_004431.1 Residues 3 to 148 of 159 are 46.57 pct identical to residues 24 to 169 of 183 from SwissProt.40 : >sp|P24577|YI71_BURCE INSERTION ELEMENT IS407 HYPOTHETICAL 20.5 KD PROTEIN (ORF1); transposase 2316254 1037713 c2473 Escherichia coli CFT073 transposase NP_754365.1 2315775 D 199310 CDS NP_754366.1 26248326 1037714 2316245..2316472 1 NC_004431.1 Residues 3 to 75 of 75 are 85.00 pct identical to residues 115 to 194 of 194 from GenPept.129 : >gb|AAL72372.1| (AF386526) transposase [Shigella flexneri 2a]; transposase 2316472 1037714 c2474 Escherichia coli CFT073 transposase NP_754366.1 2316245 D 199310 CDS NP_754367.1 26248327 1037717 complement(2316562..2316987) 1 NC_004431.1 hypothetical protein 2316987 1037717 c2475 Escherichia coli CFT073 hypothetical protein NP_754367.1 2316562 R 199310 CDS NP_754368.1 26248328 1037719 complement(2317279..2318214) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1990; Escherichia coli O157:H7 ortholog: z3150; hypothetical protein 2318214 erfK 1037719 erfK Escherichia coli CFT073 hypothetical protein NP_754368.1 2317279 R 199310 CDS NP_754369.1 26248329 1037722 complement(2318276..2319355) 1 NC_004431.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2319355 cobT 1037722 cobT Escherichia coli CFT073 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase NP_754369.1 2318276 R 199310 CDS NP_754370.1 26248330 1037726 complement(2319367..2320146) 1 NC_004431.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2320146 cobS 1037726 cobS Escherichia coli CFT073 cobalamin synthase NP_754370.1 2319367 R 199310 CDS NP_754371.1 26248331 1037729 complement(2320107..2320652) 1 NC_004431.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 2320652 cobU 1037729 cobU Escherichia coli CFT073 adenosylcobinamide kinase NP_754371.1 2320107 R 199310 CDS NP_754372.1 26248332 1037730 complement(2320804..2320926) 1 NC_004431.1 hypothetical protein 2320926 1037730 c2480 Escherichia coli CFT073 hypothetical protein NP_754372.1 2320804 R 199310 CDS NP_754373.1 26248333 1037731 complement(2321117..2321281) 1 NC_004431.1 hypothetical protein 2321281 1037731 c2481 Escherichia coli CFT073 hypothetical protein NP_754373.1 2321117 R 199310 CDS NP_754374.1 26248334 1037732 2322324..2324471 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3159; outer membrane receptor for iron compound or colicin 2324471 1037732 c2482 Escherichia coli CFT073 outer membrane receptor for iron compound or colicin NP_754374.1 2322324 D 199310 CDS NP_754375.1 26248335 1037733 2324459..2324587 1 NC_004431.1 hypothetical protein 2324587 1037733 c2483 Escherichia coli CFT073 hypothetical protein NP_754375.1 2324459 D 199310 CDS NP_754376.1 26248336 1037734 complement(2324842..2325486) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z1644; hypothetical protein 2325486 1037734 c2484 Escherichia coli CFT073 hypothetical protein NP_754376.1 2324842 R 199310 CDS NP_754377.1 26248337 1037736 complement(2325471..2326760) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z1643; hypothetical protein 2326760 1037736 c2485 Escherichia coli CFT073 hypothetical protein NP_754377.1 2325471 R 199310 CDS NP_754378.1 26248338 1037737 2327685..2328395 1 NC_004431.1 Residues 17 to 198 of 236 are 64.86 pct identical to residues 1 to 185 of 185 from SwissProt.40 : >sp|P71311|YAIS_ECOLI HYPOTHETICAL 20.5 KDA PROTEIN IN ADHC-TAUA INTERGENIC REGION; hypothetical protein 2328395 1037737 c2486 Escherichia coli CFT073 hypothetical protein NP_754378.1 2327685 D 199310 CDS NP_754379.1 26248339 1037739 2329640..2330164 1 NC_004431.1 Escherichia coli K-12 ortholog: b0359; transferase 2330164 1037739 c2489 Escherichia coli CFT073 transferase NP_754379.1 2329640 D 199310 CDS NP_754380.1 26248340 1037740 2330118..2330939 1 NC_004431.1 Escherichia coli K-12 ortholog: b0358; hypothetical protein 2330939 1037740 c2490 Escherichia coli CFT073 hypothetical protein NP_754380.1 2330118 D 199310 CDS NP_754381.1 26248341 1037744 2331944..2333158 1 NC_004431.1 Residues 1 to 404 of 404 are 80.69 pct identical to residues 1 to 404 of 404 from GenPept.129 : >gb|AAL22407.1| (AE008863) transcriptional regulator of sugar metabolism [Salmonella typhimurium LT2]; carbohydrate kinase 2333158 1037744 c2492 Escherichia coli CFT073 carbohydrate kinase NP_754381.1 2331944 D 199310 CDS NP_754382.1 26248342 1037745 2333172..2333930 1 NC_004431.1 Residues 1 to 252 of 252 are 81.74 pct identical to residues 1 to 252 of 253 from GenPept.129 : >gb|AAL22408.1| (AE008863) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 2333930 1037745 c2493 Escherichia coli CFT073 hypothetical protein NP_754382.1 2333172 D 199310 CDS NP_754383.1 26248343 1037748 2333984..2334949 1 NC_004431.1 Residues 1 to 321 of 321 are 93.76 pct identical to residues 1 to 321 of 323 from GenPept.129 : >emb|CAD08080.1| (AL627281) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 2334949 1037748 c2494 Escherichia coli CFT073 hypothetical protein NP_754383.1 2333984 D 199310 CDS NP_754384.1 26248344 1037749 2334952..2335986 1 NC_004431.1 Residues 1 to 344 of 344 are 86.62 pct identical to residues 1 to 344 of 344 from GenPept.129 : >gb|AAL22410.1| (AE008863) phosphotriesterase [Salmonella typhimurium LT2]; phosphotriesterase-related protein 2335986 1037749 c2495 Escherichia coli CFT073 phosphotriesterase-related protein NP_754384.1 2334952 D 199310 CDS NP_754385.1 26248345 1037752 complement(2336398..2336559) 1 NC_004431.1 Residues 1 to 53 of 53 are 94.33 pct identical to residues 487 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 2336559 1037752 c2496 Escherichia coli CFT073 hypothetical protein NP_754385.1 2336398 R 199310 CDS NP_754386.1 26248346 1037754 complement(2336638..2337495) 1 NC_004431.1 Residues 2 to 285 of 285 are 92.25 pct identical to residues 176 to 459 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; transposase 2337495 1037754 c2497 Escherichia coli CFT073 transposase NP_754386.1 2336638 R 199310 CDS NP_754387.1 26248347 1037758 complement(2338301..2338711) 1 NC_004431.1 Residues 1 to 129 of 136 are 97.67 pct identical to residues 30 to 158 of 173 from GenPept.129 : >gb|AAL08463.1|AF326777_38 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2338711 1037758 c2498 Escherichia coli CFT073 hypothetical protein NP_754387.1 2338301 R 199310 CDS NP_754388.1 26248348 1037759 complement(2338699..2339100) 1 NC_004431.1 Residues 1 to 121 of 133 are 87.60 pct identical to residues 1 to 121 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 2339100 1037759 c2499 Escherichia coli CFT073 hypothetical protein NP_754388.1 2338699 R 199310 CDS NP_754389.1 26248349 1037761 complement(2339266..2339871) 1 NC_004431.1 Residues 17 to 201 of 201 are 40.43 pct identical to residues 6 to 235 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 2339871 1037761 c2500 Escherichia coli CFT073 hypothetical protein NP_754389.1 2339266 R 199310 CDS NP_754390.1 26248350 1037762 complement(2340476..2340652) 1 NC_004431.1 Residues 1 to 43 of 58 are 97.67 pct identical to residues 1 to 43 of 58 from GenPept.129 : >gb|AAL08465.1|AF326777_40 (AF326777) transcriptional regulator [Shigella flexneri 2a]; hypothetical protein 2340652 1037762 c2501 Escherichia coli CFT073 hypothetical protein NP_754390.1 2340476 R 199310 CDS NP_754391.1 26248351 1037763 2340603..2340983 1 NC_004431.1 hypothetical protein 2340983 1037763 c2502 Escherichia coli CFT073 hypothetical protein NP_754391.1 2340603 D 199310 CDS NP_754392.1 26248352 1037764 2341416..2342612 1 NC_004431.1 Residues 6 to 393 of 398 are 58.82 pct identical to residues 3 to 393 of 405 from SwissProt.40 : >sp|P19780|YIS1_STRCO Insertion element IS110 hypothetical 43.6 kDa protein; transposase 2342612 1037764 c2503 Escherichia coli CFT073 transposase NP_754392.1 2341416 D 199310 CDS NP_754393.1 26248353 1037765 complement(2342382..2342519) 1 NC_004431.1 hypothetical protein 2342519 1037765 c2504 Escherichia coli CFT073 hypothetical protein NP_754393.1 2342382 R 199310 CDS NP_754394.1 26248354 1037766 2342736..2343014 1 NC_004431.1 Residues 1 to 92 of 92 are 93.47 pct identical to residues 1 to 92 of 92 from GenPept.129 : >gb|AAL08466.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2343014 1037766 c2505 Escherichia coli CFT073 hypothetical protein NP_754394.1 2342736 D 199310 CDS NP_754395.1 26248355 1037767 2343093..2343332 1 NC_004431.1 Residues 4 to 78 of 79 are 97.33 pct identical to residues 1 to 75 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2343332 1037767 c2506 Escherichia coli CFT073 hypothetical protein NP_754395.1 2343093 D 199310 CDS NP_754396.1 26248356 1037768 2344396..2344920 1 NC_004431.1 Residues 1 to 174 of 174 are 99.42 pct identical to residues 315 to 488 of 488 from GenPept.129 : >gb|AAL67386.1|AF447814_54 (AF447814) R6-like protein [Escherichia coli]; hypothetical protein 2344920 1037768 c2508 Escherichia coli CFT073 hypothetical protein NP_754396.1 2344396 D 199310 CDS NP_754397.1 26248357 1037769 2344917..2345672 1 NC_004431.1 Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; insertion sequence ATP-binding protein 2345672 1037769 c2509 Escherichia coli CFT073 insertion sequence ATP-binding protein NP_754397.1 2344917 D 199310 CDS NP_754398.1 26248358 1037770 2345772..2346125 1 NC_004431.1 Residues 1 to 113 of 117 are 84.95 pct identical to residues 86 to 198 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2346125 1037770 c2510 Escherichia coli CFT073 hypothetical protein NP_754398.1 2345772 D 199310 CDS NP_754399.1 26248359 1037774 complement(2347151..2347933) 1 NC_004431.1 Residues 10 to 256 of 260 are 46.96 pct identical to residues 4 to 248 of 265 from SwissProt.40 : >sp|P15026|ISTB_PSEAE Insertion sequence IS21 ATP-binding protein; transposase/IS protein 2347933 1037774 c2511 Escherichia coli CFT073 transposase/IS protein NP_754399.1 2347151 R 199310 CDS NP_754400.1 26248360 1037776 complement(2347930..2348952) 1 NC_004431.1 Residues 1 to 340 of 340 are 99.70 pct identical to residues 1 to 340 of 340 from GenPept.129 : >emb|CAC43410.1| (X16664) Y1093 protein [Escherichia coli]; transposase 2348952 1037776 c2512 Escherichia coli CFT073 transposase NP_754400.1 2347930 R 199310 CDS NP_754401.1 26248361 1037778 complement(2349503..2349880) 1 NC_004431.1 hypothetical protein 2349880 1037778 c2513 Escherichia coli CFT073 hypothetical protein NP_754401.1 2349503 R 199310 CDS NP_754402.1 26248362 1037780 2350449..2351621 1 NC_004431.1 hypothetical protein 2351621 1037780 c2514 Escherichia coli CFT073 hypothetical protein NP_754402.1 2350449 D 199310 CDS NP_754403.1 26248363 1037781 complement(2352463..2353230) 1 NC_004431.1 Residues 1 to 255 of 255 are 100.00 pct identical to residues 1 to 255 of 255 from GenPept.129 : >gb|AAL67370.1|AF447814_38 (AF447814) ferric-enterobactin-transport protein [Escherichia coli]; ABC transporter 2353230 1037781 c2515 Escherichia coli CFT073 ABC transporter NP_754403.1 2352463 R 199310 CDS NP_754404.1 26248364 1037782 complement(2353227..2354285) 1 NC_004431.1 Residues 1 to 352 of 352 are 100.00 pct identical to residues 1 to 352 of 352 from GenPept.129 : >gb|AAL67369.1|AF447814_37 (AF447814) permease [Escherichia coli]; ABC transporter 2354285 1037782 c2516 Escherichia coli CFT073 ABC transporter NP_754404.1 2353227 R 199310 CDS NP_754405.1 26248365 1037783 complement(2354304..2355296) 1 NC_004431.1 Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]; periplasmic binding protein 2355296 1037783 c2517 Escherichia coli CFT073 periplasmic binding protein NP_754405.1 2354304 R 199310 CDS NP_754406.1 26248366 1037784 complement(2355304..2357469) 1 NC_004431.1 Residues 1 to 530 of 721 are 100.00 pct identical to residues 1 to 530 of 536 from GenPept.129 : >gb|AAL67366.1|AF447814_34 (AF447814) truncated ferric siderophore receptor [Escherichia coli]; TonB dependent receptor 2357469 1037784 c2518 Escherichia coli CFT073 TonB dependent receptor NP_754406.1 2355304 R 199310 CDS NP_754407.1 26248367 1037786 2358550..2360934 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1652; hypothetical protein 2360934 1037786 c2520 Escherichia coli CFT073 hypothetical protein NP_754407.1 2358550 D 199310 CDS NP_754408.1 26248368 1037787 complement(2360110..2360286) 1 NC_004431.1 hypothetical protein 2360286 1037787 c2521 Escherichia coli CFT073 hypothetical protein NP_754408.1 2360110 R 199310 CDS NP_754409.1 26248369 1037788 2360931..2361836 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1653; hypothetical protein 2361836 1037788 c2522 Escherichia coli CFT073 hypothetical protein NP_754409.1 2360931 D 199310 CDS NP_754410.1 26248370 1037789 2361833..2362903 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1654; hypothetical protein 2362903 1037789 c2523 Escherichia coli CFT073 hypothetical protein NP_754410.1 2361833 D 199310 CDS NP_754411.1 26248371 1037791 2362931..2363716 1 NC_004431.1 Residues 37 to 261 of 261 are 91.18 pct identical to residues 1 to 227 of 227 from GenPept.129 : >dbj|BAB36222.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 2363716 1037791 c2524 Escherichia coli CFT073 hypothetical protein NP_754411.1 2362931 D 199310 CDS NP_754412.1 26248372 1037792 2363732..2364142 1 NC_004431.1 Residues 1 to 135 of 136 are 95.55 pct identical to residues 1 to 135 of 136 from GenPept.129 : >dbj|BAB36223.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 2364142 1037792 c2525 Escherichia coli CFT073 hypothetical protein NP_754412.1 2363732 D 199310 CDS NP_754413.1 26248373 1037793 2364363..2365184 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 2365184 1037793 c2526 Escherichia coli CFT073 hypothetical protein NP_754413.1 2364363 D 199310 CDS NP_754414.1 26248374 1037794 2365275..2365760 1 NC_004431.1 Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 2365760 1037794 c2527 Escherichia coli CFT073 hypothetical protein NP_754414.1 2365275 D 199310 CDS NP_754415.1 26248375 1037795 complement(2365329..2365868) 1 NC_004431.1 Residues 1 to 174 of 179 are 87.93 pct identical to residues 125 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 2365868 1037795 c2528 Escherichia coli CFT073 hypothetical protein NP_754415.1 2365329 R 199310 CDS NP_754416.1 26248376 1037797 2365806..2366252 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 2366252 1037797 c2529 Escherichia coli CFT073 radC-like protein yeeS NP_754416.1 2365806 D 199310 CDS NP_754417.1 26248377 1037801 2366321..2366542 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z3163; hypothetical protein 2366542 1037801 c2530 Escherichia coli CFT073 hypothetical protein NP_754417.1 2366321 D 199310 CDS NP_754418.1 26248378 1037802 2366616..2366984 1 NC_004431.1 Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein 2366984 1037802 c2531 Escherichia coli CFT073 hypothetical protein NP_754418.1 2366616 D 199310 CDS NP_754419.1 26248379 1037803 2367073..2367447 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 2367447 1037803 c2532 Escherichia coli CFT073 hypothetical protein NP_754419.1 2367073 D 199310 CDS NP_754420.1 26248380 1037804 2367444..2367638 1 NC_004431.1 Escherichia coli K-12 ortholog: b2006; Escherichia coli O157:H7 ortholog: z3166; hypothetical protein 2367638 yeeW 1037804 yeeW Escherichia coli CFT073 hypothetical protein NP_754420.1 2367444 D 199310 CDS NP_754421.1 26248381 1037806 complement(2368536..2368931) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2007; Escherichia coli O157:H7 ortholog: z3168; hypothetical protein 2368931 yeeX 1037806 yeeX Escherichia coli CFT073 hypothetical protein NP_754421.1 2368536 R 199310 CDS NP_754422.1 26248382 1037807 2368950..2369072 1 NC_004431.1 hypothetical protein 2369072 1037807 c2535 Escherichia coli CFT073 hypothetical protein NP_754422.1 2368950 D 199310 CDS NP_754423.1 26248383 1037809 complement(2369037..2370095) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2008; Escherichia coli O157:H7 ortholog: z3169; hypothetical protein 2370095 yeeA 1037809 yeeA Escherichia coli CFT073 hypothetical protein NP_754423.1 2369037 R 199310 CDS NP_754424.1 26248384 1037810 complement(2370293..2370766) 1 NC_004431.1 SbmC protein; Escherichia coli K-12 ortholog: b2009; Escherichia coli O157:H7 ortholog: z3170; DNA gyrase inhibitor 2370766 sbmC 1037810 sbmC Escherichia coli CFT073 DNA gyrase inhibitor NP_754424.1 2370293 R 199310 CDS NP_754425.1 26248385 1037811 complement(2370885..2372057) 1 NC_004431.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2372057 dacD 1037811 dacD Escherichia coli CFT073 D-alanyl-D-alanine carboxypeptidase NP_754425.1 2370885 R 199310 CDS NP_754426.2 161486193 1037812 2372260..2373687 1 NC_004431.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2373687 sbcB 1037812 sbcB Escherichia coli CFT073 exonuclease I NP_754426.2 2372260 D 199310 CDS NP_754427.1 26248387 1037813 complement(2373761..2375125) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2014; Escherichia coli O157:H7 ortholog: z3176; transport protein YeeF 2375125 yeeF 1037813 yeeF Escherichia coli CFT073 transport protein YeeF NP_754427.1 2373761 R 199310 CDS NP_754428.1 26248388 1037814 complement(2375301..2375438) 1 NC_004431.1 hypothetical protein 2375438 1037814 c2541 Escherichia coli CFT073 hypothetical protein NP_754428.1 2375301 R 199310 CDS NP_754429.1 26248389 1037816 complement(2375386..2376336) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2015; Escherichia coli O157:H7 ortholog: z3177; transcriptional regulator YeeY 2376336 yeeY 1037816 yeeY Escherichia coli CFT073 transcriptional regulator YeeY NP_754429.1 2375386 R 199310 CDS NP_754430.1 26248390 1037817 complement(2376361..2377185) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2016; Escherichia coli O157:H7 ortholog: z3178; hypothetical protein 2377185 1037817 c2543 Escherichia coli CFT073 hypothetical protein NP_754430.1 2376361 R 199310 CDS NP_754431.1 26248391 1037818 complement(2377268..2377522) 1 NC_004431.1 Residues 1 to 84 of 84 are 98.80 pct identical to residues 1 to 84 of 84 from SwissProt.40 : >sp|P56605|YOEB_ECOLI Hypothetical protein yoeB; hypothetical protein 2377522 1037818 c2544 Escherichia coli CFT073 hypothetical protein NP_754431.1 2377268 R 199310 CDS NP_754432.2 161486192 1037819 complement(2377519..2377770) 1 NC_004431.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2377770 yefM 1037819 yefM Escherichia coli CFT073 antitoxin YefM NP_754432.2 2377519 R 199310 CDS NP_754434.1 26248394 1037821 2378249..2379148 1 NC_004431.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2379148 hisG 1037821 hisG Escherichia coli CFT073 ATP phosphoribosyltransferase NP_754434.1 2378249 D 199310 CDS NP_754435.1 26248395 1037822 2379145..2380458 1 NC_004431.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2380458 hisD 1037822 hisD Escherichia coli CFT073 histidinol dehydrogenase NP_754435.1 2379145 D 199310 CDS NP_754436.1 26248396 1037823 2380455..2381525 1 NC_004431.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2381525 hisC 1037823 hisC Escherichia coli CFT073 histidinol-phosphate aminotransferase NP_754436.1 2380455 D 199310 CDS NP_754437.2 161486191 1037824 2381525..2382592 1 NC_004431.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2382592 hisB 1037824 hisB Escherichia coli CFT073 imidazole glycerol-phosphate dehydratase/histidinol phosphatase NP_754437.2 2381525 D 199310 CDS NP_754438.1 26248398 1037825 2382592..2383182 1 NC_004431.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2383182 hisH 1037825 hisH Escherichia coli CFT073 imidazole glycerol phosphate synthase subunit HisH NP_754438.1 2382592 D 199310 CDS NP_754439.2 161486190 1037827 2383182..2383919 1 NC_004431.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2383919 hisA 1037827 hisA Escherichia coli CFT073 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NP_754439.2 2383182 D 199310 CDS NP_754440.1 26248400 1037828 2383901..2384677 1 NC_004431.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2384677 hisF 1037828 hisF Escherichia coli CFT073 imidazole glycerol phosphate synthase subunit HisF NP_754440.1 2383901 D 199310 CDS NP_754441.1 26248401 1037829 2384671..2385282 1 NC_004431.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2385282 hisI 1037829 hisI Escherichia coli CFT073 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein NP_754441.1 2384671 D 199310 CDS NP_754442.1 26248402 1037830 complement(2385469..2386482) 1 NC_004431.1 Polysaccharide antigen chain regulator; Escherichia coli K-12 ortholog: b2027; Escherichia coli O157:H7 ortholog: z3189; chain length determinant protein 2386482 wzzB 1037830 wzzB Escherichia coli CFT073 chain length determinant protein NP_754442.1 2385469 R 199310 CDS NP_754443.1 26248403 1037832 complement(2386589..2387755) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2028; Escherichia coli O157:H7 ortholog: z3190; UDP-glucose 6-dehydrogenase 2387755 ugd 1037832 ugd Escherichia coli CFT073 UDP-glucose 6-dehydrogenase NP_754443.1 2386589 R 199310 CDS NP_754444.1 26248404 1037833 complement(2388005..2389411) 1 NC_004431.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2389411 gnd 1037833 gnd Escherichia coli CFT073 6-phosphogluconate dehydrogenase NP_754444.1 2388005 R 199310 CDS NP_754445.1 26248405 1037835 complement(2389574..2390944) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2048; Escherichia coli O157:H7 ortholog: z3194; phosphomannomutase 2390944 manB 1037835 manB Escherichia coli CFT073 phosphomannomutase NP_754445.1 2389574 R 199310 CDS NP_754446.1 26248406 1037836 complement(2391027..2392478) 1 NC_004431.1 GDP; Escherichia coli K-12 ortholog: b2049; Escherichia coli O157:H7 ortholog: z3213; mannose-1-phosphate guanylyltransferase 2392478 1037836 c2558 Escherichia coli CFT073 mannose-1-phosphate guanylyltransferase NP_754446.1 2391027 R 199310 CDS NP_754447.1 26248407 1037838 complement(2392456..2393571) 1 NC_004431.1 Residues 2 to 365 of 371 are 50.00 pct identical to residues 28 to 394 of 399 from GenPept.129 : >gb|AAB49389.1| (M84642) orf7.17; function unknown [Salmonella enterica]; hypothetical protein 2393571 1037838 c2559 Escherichia coli CFT073 hypothetical protein NP_754447.1 2392456 R 199310 CDS NP_754448.1 26248408 1037839 complement(2393682..2394689) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0759; Escherichia coli O157:H7 ortholog: z0929; UDP-glucose 4-epimerase 2394689 1037839 c2560 Escherichia coli CFT073 UDP-glucose 4-epimerase NP_754448.1 2393682 R 199310 CDS NP_754449.1 26248409 1037842 complement(2394706..2395851) 1 NC_004431.1 Residues 83 to 355 of 381 are 22.83 pct identical to residues 512 to 777 of 812 from GenPept.129 : >gb|AAM04600.1| (AE010785) glycosyltransferase [Methanosarcina acetivorans str. C2A]; hypothetical protein 2395851 1037842 c2561 Escherichia coli CFT073 hypothetical protein NP_754449.1 2394706 R 199310 CDS NP_754450.1 26248410 1037843 complement(2395838..2396920) 1 NC_004431.1 Residues 169 to 353 of 360 are 27.89 pct identical to residues 153 to 336 of 336 from GenPept.129 : >gb|AAL80431.1| (AE010155) glycosyltransferase [Pyrococcus furiosus DSM 3638]; glycosyl transferase 2396920 1037843 c2562 Escherichia coli CFT073 glycosyl transferase NP_754450.1 2395838 R 199310 CDS NP_754451.1 26248411 1037844 complement(2396866..2397735) 1 NC_004431.1 Residues 9 to 179 of 289 are 31.21 pct identical to residues 8 to 173 of 327 from GenPept.129 : >gb|AAC69672.1| (AF019746) beta1,3-glucosyltransferase WaaV [Escherichia coli]; glycosyl transferase 2397735 1037844 c2563 Escherichia coli CFT073 glycosyl transferase NP_754451.1 2396866 R 199310 CDS NP_754452.1 26248412 1037846 complement(2397732..2399093) 1 NC_004431.1 Residues 338 to 445 of 453 are 28.81 pct identical to residues 357 to 474 of 477 from GenPept.129 : >gb|AAL00026.1| (AE008494) Hypothetical protein [Streptococcus pneumoniae R6]; hypothetical protein 2399093 1037846 c2564 Escherichia coli CFT073 hypothetical protein NP_754452.1 2397732 R 199310 CDS YP_004853815.1 347357913 1037848 complement(2398412..2398534) 1 NC_004431.1 hypothetical protein 2398534 1037848 c2565 Escherichia coli CFT073 hypothetical protein YP_004853815.1 2398412 R 199310 CDS NP_754454.1 26248414 1037850 complement(2399075..2400331) 1 NC_004431.1 Residues 11 to 409 of 418 are 24.94 pct identical to residues 7 to 412 of 431 from GenPept.129 : >gb|AAK81005.1|AE007803_8 (AE007803) Possible O-antigen/teichoic acid transporter [Clostridium acetobutylicum]; hypothetical protein 2400331 1037850 c2566 Escherichia coli CFT073 hypothetical protein NP_754454.1 2399075 R 199310 CDS NP_754455.1 26248415 1037852 complement(2400688..2401593) 1 NC_004431.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 2401593 galF 1037852 galF Escherichia coli CFT073 UTP-glucose-1-phosphate uridylyltransferase NP_754455.1 2400688 R 199310 CDS NP_754456.1 26248416 1037853 complement(2401756..2403150) 1 NC_004431.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2403150 wcaM 1037853 wcaM Escherichia coli CFT073 colanic acid biosynthesis protein NP_754456.1 2401756 R 199310 CDS NP_754457.1 26248417 1037854 complement(2403161..2404381) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2044; Escherichia coli O157:H7 ortholog: z3208; colanic acid biosynthesis glycosyl transferase wcaL 2404381 wcaL 1037854 wcaL Escherichia coli CFT073 colanic acid biosynthesis glycosyl transferase wcaL NP_754457.1 2403161 R 199310 CDS NP_754458.1 26248418 1037855 complement(2404378..2405658) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2045; Escherichia coli O157:H7 ortholog: z3209; pyruvyl transferase 2405658 wcaK 1037855 wcaK Escherichia coli CFT073 pyruvyl transferase NP_754458.1 2404378 R 199310 CDS NP_754459.1 26248419 1037856 complement(2406127..2407605) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2046; Escherichia coli O157:H7 ortholog: z3210; colanic acid exporter 2407605 wzxC 1037856 wzxC Escherichia coli CFT073 colanic acid exporter NP_754459.1 2406127 R 199310 CDS NP_754460.1 26248420 1037858 complement(2407607..2409001) 1 NC_004431.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2409001 wcaJ 1037858 wcaJ Escherichia coli CFT073 UDP-glucose lipid carrier transferase NP_754460.1 2407607 R 199310 CDS NP_754461.1 26248421 1037861 complement(2409057..2410475) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2048; Escherichia coli O157:H7 ortholog: z3212; phosphomannomutase 2410475 cpsG 1037861 cpsG Escherichia coli CFT073 phosphomannomutase NP_754461.1 2409057 R 199310 CDS NP_754462.1 26248422 1037864 2410453..2410611 1 NC_004431.1 hypothetical protein 2410611 1037864 c2574 Escherichia coli CFT073 hypothetical protein NP_754462.1 2410453 D 199310 CDS NP_754463.1 26248423 1037865 complement(2410620..2412056) 1 NC_004431.1 GDP; Escherichia coli K-12 ortholog: b2049; Escherichia coli O157:H7 ortholog: z3213; mannose-1-phosphate guanylyltransferase 2412056 cpsB 1037865 cpsB Escherichia coli CFT073 mannose-1-phosphate guanylyltransferase NP_754463.1 2410620 R 199310 CDS NP_754464.1 26248424 1037867 complement(2412059..2413282) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2050; Escherichia coli O157:H7 ortholog: z3214; glycosyl transferase 2413282 wcaI 1037867 wcaI Escherichia coli CFT073 glycosyl transferase NP_754464.1 2412059 R 199310 CDS NP_754465.1 26248425 1037868 complement(2413279..2413761) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2051; Escherichia coli O157:H7 ortholog: z3215; GDP-mannose mannosyl hydrolase 2413761 wcaH 1037868 wcaH Escherichia coli CFT073 GDP-mannose mannosyl hydrolase NP_754465.1 2413279 R 199310 CDS NP_754466.1 26248426 1037870 complement(2413761..2414726) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2052; Escherichia coli O157:H7 ortholog: z3216; bifunctional; GDP-fucose synthetase; GDP-mannose-4-keto-6-D epimerase; GDP-4-keto-6-L-galactose reductase 2414726 wcaG 1037870 wcaG Escherichia coli CFT073 GDP-4-keto-6-L-galactose reductase NP_754466.1 2413761 R 199310 CDS NP_754467.1 26248427 1037872 complement(2414729..2415850) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2053; Escherichia coli O157:H7 ortholog: z3217; GDP-mannose 4,6-dehydratase 2415850 gmd 1037872 gmd Escherichia coli CFT073 GDP-mannose 4,6-dehydratase NP_754467.1 2414729 R 199310 CDS NP_754468.1 26248428 1037873 complement(2415877..2416425) 1 NC_004431.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2416425 wcaF 1037873 wcaF Escherichia coli CFT073 colanic acid biosynthesis acetyltransferase WcaF NP_754468.1 2415877 R 199310 CDS NP_754469.1 26248429 1037874 complement(2416441..2417187) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2055; Escherichia coli O157:H7 ortholog: z3219; glycosyl transferase 2417187 wcaE 1037874 wcaE Escherichia coli CFT073 glycosyl transferase NP_754469.1 2416441 R 199310 CDS NP_754470.2 229106377 1037877 complement(2417198..2418415) 1 NC_004431.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2418415 wcaD 1037877 wcaD Escherichia coli CFT073 colanic acid biosynthesis protein NP_754470.2 2417198 R 199310 CDS NP_754471.1 26248431 1037879 complement(2418390..2419607) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2057; Escherichia coli O157:H7 ortholog: z3221; glycosyl transferase 2419607 wcaC 1037879 wcaC Escherichia coli CFT073 glycosyl transferase NP_754471.1 2418390 R 199310 CDS NP_754472.1 26248432 1037882 complement(2419604..2420092) 1 NC_004431.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2420092 wcaB 1037882 wcaB Escherichia coli CFT073 colanic acid biosynthesis acetyltransferase WcaB NP_754472.1 2419604 R 199310 CDS NP_754473.1 26248433 1037883 complement(2420095..2420934) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2059; Escherichia coli O157:H7 ortholog: z3223; glycosyl transferase 2420934 wcaA 1037883 wcaA Escherichia coli CFT073 glycosyl transferase NP_754473.1 2420095 R 199310 CDS NP_754474.2 161486189 1037884 complement(2421027..2423189) 1 NC_004431.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2423189 1037884 c2586 Escherichia coli CFT073 tyrosine kinase NP_754474.2 2421027 R 199310 CDS NP_754475.1 26248435 1037885 complement(2423192..2423422) 1 NC_004431.1 Residues 1 to 76 of 76 are 98.68 pct identical to residues 72 to 147 of 147 from GenPept.129 : >gb|AAC77834.1| (U38473) acid phosphatase [Escherichia coli]; hypothetical protein 2423422 1037885 c2587 Escherichia coli CFT073 hypothetical protein NP_754475.1 2423192 R 199310 CDS NP_754476.1 26248436 1037888 complement(2423638..2424141) 1 NC_004431.1 Residues 1 to 167 of 167 are 98.80 pct identical to residues 213 to 379 of 379 from GenPept.129 : >gb|AAG57122.1|AE005432_3 (AE005432) polysaccharide export protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 2424141 1037888 c2588 Escherichia coli CFT073 hypothetical protein NP_754476.1 2423638 R 199310 CDS NP_754477.1 26248437 1037890 complement(2424132..2424776) 1 NC_004431.1 Residues 1 to 211 of 214 are 99.52 pct identical to residues 1 to 211 of 379 from MG1655 : b2062; hypothetical protein 2424776 1037890 c2589 Escherichia coli CFT073 hypothetical protein NP_754477.1 2424132 R 199310 CDS NP_754478.1 26248438 1037892 2425369..2427018 1 NC_004431.1 Escherichia coli K-12 ortholog: b2063; Escherichia coli O157:H7 ortholog: z3229; hypothetical protein 2427018 yegH 1037892 yegH Escherichia coli CFT073 hypothetical protein NP_754478.1 2425369 D 199310 CDS NP_754479.1 26248439 1037893 complement(2427086..2428939) 1 NC_004431.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2428939 asmA 1037893 asmA Escherichia coli CFT073 assembly protein NP_754479.1 2427086 R 199310 CDS NP_754480.1 26248440 1037894 complement(2428961..2429542) 1 NC_004431.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2429542 dcd 1037894 dcd Escherichia coli CFT073 deoxycytidine triphosphate deaminase NP_754480.1 2428961 R 199310 CDS NP_754481.2 161486188 1037895 complement(2429634..2430275) 1 NC_004431.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2430275 udk 1037895 udk Escherichia coli CFT073 uridine kinase NP_754481.2 2429634 R 199310 CDS NP_754482.1 26248442 1037897 2430593..2433910 1 NC_004431.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2433910 yegE 1037897 yegE Escherichia coli CFT073 sensor protein NP_754482.1 2430593 D 199310 CDS NP_754483.1 26248443 1037898 complement(2434020..2434868) 1 NC_004431.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase 2434868 alkA 1037898 alkA Escherichia coli CFT073 3-methyl-adenine DNA glycosylase NP_754483.1 2434020 R 199310 CDS NP_754484.2 161486187 1037901 2435002..2436354 1 NC_004431.1 Escherichia coli K-12 ortholog: b2069; Escherichia coli O157:H7 ortholog: z3238; chaperone 2436354 yegD 1037901 yegD Escherichia coli CFT073 chaperone NP_754484.2 2435002 D 199310 CDS NP_754485.1 26248445 1037904 complement(2436367..2438316) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2070; Escherichia coli O157:H7 ortholog: z3239; hypothetical protein 2438316 yegI 1037904 yegI Escherichia coli CFT073 hypothetical protein NP_754485.1 2436367 R 199310 CDS NP_754486.1 26248446 1037905 complement(2438304..2439065) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2072; Escherichia coli O157:H7 ortholog: z3240; hypothetical protein 2439065 yegK 1037905 yegK Escherichia coli CFT073 hypothetical protein NP_754486.1 2438304 R 199310 CDS NP_754487.1 26248447 1037906 complement(2439062..2439721) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2073; Escherichia coli O157:H7 ortholog: z3241; hypothetical protein 2439721 yegL 1037906 yegL Escherichia coli CFT073 hypothetical protein NP_754487.1 2439062 R 199310 CDS NP_754488.2 161486186 1037908 2440602..2441849 1 NC_004431.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2441849 yegM 1037908 yegM Escherichia coli CFT073 multidrug efflux system subunit MdtA NP_754488.2 2440602 D 199310 CDS NP_754489.1 26248449 1037909 2441849..2444971 1 NC_004431.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2444971 yegN 1037909 yegN Escherichia coli CFT073 multidrug efflux system subunit MdtB NP_754489.1 2441849 D 199310 CDS NP_754490.1 26248450 1037912 2444972..2448049 1 NC_004431.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2448049 yegO 1037912 yegO Escherichia coli CFT073 multidrug efflux system subunit MdtC NP_754490.1 2444972 D 199310 CDS NP_754491.1 26248451 1037913 2448050..2449465 1 NC_004431.1 Escherichia coli K-12 ortholog: b2077; Escherichia coli O157:H7 ortholog: z3246; multidrug efflux system protein MdtE 2449465 yegB 1037913 yegB Escherichia coli CFT073 multidrug efflux system protein MdtE NP_754491.1 2448050 D 199310 CDS NP_754492.1 26248452 1037914 2449462..2450865 1 NC_004431.1 Escherichia coli K-12 ortholog: b2078; Escherichia coli O157:H7 ortholog: z3247; signal transduction histidine-protein kinase BaeS 2450865 baeS 1037914 baeS Escherichia coli CFT073 signal transduction histidine-protein kinase BaeS NP_754492.1 2449462 D 199310 CDS NP_754493.1 26248453 1037915 2450862..2451584 1 NC_004431.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2451584 baeR 1037915 baeR Escherichia coli CFT073 DNA-binding transcriptional regulator BaeR NP_754493.1 2450862 D 199310 CDS NP_754494.1 26248454 1037916 2451725..2452096 1 NC_004431.1 Escherichia coli K-12 ortholog: b2080; Escherichia coli O157:H7 ortholog: z3249; hypothetical protein 2452096 yegP 1037916 yegP Escherichia coli CFT073 hypothetical protein NP_754494.1 2451725 D 199310 CDS NP_754495.1 26248455 1037918 complement(2452221..2452835) 1 NC_004431.1 Residues 6 to 204 of 204 are 37.61 pct identical to residues 1 to 205 of 205 from GenPept.129 : >emb|CAD02514.1| (AL627273) exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 2452835 1037918 c2607 Escherichia coli CFT073 hypothetical protein NP_754495.1 2452221 R 199310 CDS NP_754496.1 26248456 1037920 complement(2452887..2455034) 1 NC_004431.1 Residues 14 to 715 of 715 are 65.00 pct identical to residues 1 to 703 of 703 from GenPept.129 : >gb|AAL21038.1| (AE008795) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 2455034 1037920 c2608 Escherichia coli CFT073 hypothetical protein NP_754496.1 2452887 R 199310 CDS NP_754497.1 26248457 1037921 complement(2455006..2455722) 1 NC_004431.1 Residues 5 to 237 of 238 are 65.38 pct identical to residues 4 to 237 of 238 from GenPept.129 : >gb|AAL21037.1| (AE008795) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 2455722 1037921 c2609 Escherichia coli CFT073 hypothetical protein NP_754497.1 2455006 R 199310 CDS NP_754498.1 26248458 1037925 complement(2455722..2456936) 1 NC_004431.1 Residues 111 to 399 of 404 are 65.39 pct identical to residues 1 to 289 of 294 from GenPept.129 : >emb|CAD02496.1| (AL627273) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 2456936 1037925 c2610 Escherichia coli CFT073 hypothetical protein NP_754498.1 2455722 R 199310 CDS NP_754499.1 26248459 1037927 2457424..2458785 1 NC_004431.1 Escherichia coli K-12 ortholog: b2081; Escherichia coli O157:H7 ortholog: z3250; protease yegQ 2458785 yegQ 1037927 yegQ Escherichia coli CFT073 protease yegQ NP_754499.1 2457424 D 199310 CDS NP_754500.1 26248460 1037928 complement(2458725..2458862) 1 NC_004431.1 hypothetical protein 2458862 1037928 c2612 Escherichia coli CFT073 hypothetical protein NP_754500.1 2458725 R 199310 CDS NP_754501.1 26248461 1037929 complement(2459285..2459617) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2085; Escherichia coli O157:H7 ortholog: z3251; hypothetical protein 2459617 yegR 1037929 yegR Escherichia coli CFT073 hypothetical protein NP_754501.1 2459285 R 199310 CDS NP_754502.1 26248462 1037932 2460017..2460916 1 NC_004431.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2460916 yegS 1037932 yegS Escherichia coli CFT073 lipid kinase NP_754502.1 2460017 D 199310 CDS NP_754503.1 26248463 1037933 complement(2460998..2461777) 1 NC_004431.1 Possible Fusion of Escherichia coli K-12 B2087 and B2091; Residues 1 to 259 of 259 are 99.61 pct identical to residues 1 to 259 of 259 from SwissProt.40 : >sp|P36930|GATR_ECOLI GALACTITOL UTILIZATION OPERON REPRESSOR; hypothetical protein 2461777 1037933 c2615 Escherichia coli CFT073 hypothetical protein NP_754503.1 2460998 R 199310 CDS NP_754504.1 26248464 1037934 complement(2461877..2462917) 1 NC_004431.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2462917 gatD 1037934 gatD Escherichia coli CFT073 galactitol-1-phosphate dehydrogenase NP_754504.1 2461877 R 199310 CDS NP_754505.1 26248465 1037935 complement(2462965..2464320) 1 NC_004431.1 EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z3255; PTS system, galactitol-specific IIC component 2464320 gatC 1037935 gatC Escherichia coli CFT073 PTS system, galactitol-specific IIC component NP_754505.1 2462965 R 199310 CDS NP_754506.1 26248466 1037936 complement(2464324..2464608) 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2464608 gatB 1037936 gatB Escherichia coli CFT073 PTS system galactitol-specific transporter subunit IIB NP_754506.1 2464324 R 199310 CDS NP_754507.1 26248467 1037937 complement(2464639..2465091) 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2465091 gatA 1037937 gatA Escherichia coli CFT073 PTS system galactitol-specific transporter subunit IIA NP_754507.1 2464639 R 199310 CDS NP_754508.1 26248468 1037939 complement(2465101..2466363) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2095; Escherichia coli O157:H7 ortholog: z3258; tagatose 6-phosphate kinase gatZ 2466363 gatZ 1037939 gatZ Escherichia coli CFT073 tagatose 6-phosphate kinase gatZ NP_754508.1 2465101 R 199310 CDS NP_754509.2 161486185 1037940 complement(2466392..2467246) 1 NC_004431.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2467246 gatY 1037940 gatY Escherichia coli CFT073 tagatose-bisphosphate aldolase NP_754509.2 2466392 R 199310 CDS NP_754510.1 26248470 1037943 complement(2467471..2467980) 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 2467980 1037943 c2622 Escherichia coli CFT073 transposase NP_754510.1 2467471 R 199310 CDS NP_754511.2 161486184 1037944 complement(2468184..2469236) 1 NC_004431.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2469236 1037944 c2623 Escherichia coli CFT073 fructose-bisphosphate aldolase NP_754511.2 2468184 R 199310 CDS NP_754512.1 26248472 1037946 2469295..2469441 1 NC_004431.1 hypothetical protein 2469441 1037946 c2624 Escherichia coli CFT073 hypothetical protein NP_754512.1 2469295 D 199310 CDS NP_754513.1 26248473 1037948 2469493..2470770 1 NC_004431.1 Escherichia coli K-12 ortholog: b2098; Escherichia coli O157:H7 ortholog: z3261; nucleoside transporter yegT 2470770 yegT 1037948 yegT Escherichia coli CFT073 nucleoside transporter yegT NP_754513.1 2469493 D 199310 CDS NP_754514.1 26248474 1037949 2470767..2471771 1 NC_004431.1 Escherichia coli K-12 ortholog: b2099; Escherichia coli O157:H7 ortholog: z3262; hypothetical protein 2471771 yegU 1037949 yegU Escherichia coli CFT073 hypothetical protein NP_754514.1 2470767 D 199310 CDS NP_754515.1 26248475 1037950 2471768..2472733 1 NC_004431.1 Escherichia coli K-12 ortholog: b2100; Escherichia coli O157:H7 ortholog: z3263; sugar kinase yegV 2472733 yegV 1037950 yegV Escherichia coli CFT073 sugar kinase yegV NP_754515.1 2471768 D 199310 CDS NP_754516.1 26248476 1037951 complement(2472707..2473453) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2101; Escherichia coli O157:H7 ortholog: z3264; transcriptional regulator YegW 2473453 yegW 1037951 yegW Escherichia coli CFT073 transcriptional regulator YegW NP_754516.1 2472707 R 199310 CDS NP_754517.1 26248477 1037952 complement(2473505..2474332) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2102; Escherichia coli O157:H7 ortholog: z3266; hypothetical protein 2474332 yegX 1037952 yegX Escherichia coli CFT073 hypothetical protein NP_754517.1 2473505 R 199310 CDS NP_754518.1 26248478 1037953 complement(2474388..2475188) 1 NC_004431.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2475188 thiD 1037953 thiD Escherichia coli CFT073 phosphomethylpyrimidine kinase NP_754518.1 2474388 R 199310 CDS NP_754519.1 26248479 1037956 complement(2475185..2475973) 1 NC_004431.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2475973 thiM 1037956 thiM Escherichia coli CFT073 hydroxyethylthiazole kinase NP_754519.1 2475185 R 199310 CDS NP_754520.1 26248480 1037957 complement(2476196..2476468) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2105; Escherichia coli O157:H7 ortholog: z3273; hypothetical protein 2476468 yohL 1037957 yohL Escherichia coli CFT073 hypothetical protein NP_754520.1 2476196 R 199310 CDS NP_754521.1 26248481 1037958 2476589..2477413 1 NC_004431.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2477413 yohM 1037958 yohM Escherichia coli CFT073 nickel/cobalt efflux protein RcnA NP_754521.1 2476589 D 199310 CDS NP_754522.1 26248482 1037960 2477452..2477970 1 NC_004431.1 Escherichia coli K-12 ortholog: b2107; Escherichia coli O157:H7 ortholog: z3275; hypothetical protein 2477970 yohN 1037960 yohN Escherichia coli CFT073 hypothetical protein NP_754522.1 2477452 D 199310 CDS NP_754523.1 26248483 1037961 complement(2478052..2479086) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2108; hypothetical protein 2479086 yehA 1037961 yehA Escherichia coli CFT073 hypothetical protein NP_754523.1 2478052 R 199310 CDS NP_754524.1 26248484 1037962 complement(2479102..2481597) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2109; Escherichia coli O157:H7 ortholog: z3277; outer membrane usher protein yehB 2481597 yehB 1037962 yehB Escherichia coli CFT073 outer membrane usher protein yehB NP_754524.1 2479102 R 199310 CDS NP_754525.1 26248485 1037963 complement(2481598..2482272) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2110; Escherichia coli O157:H7 ortholog: z3278; fimbrial chaperone yehC 2482272 yehC 1037963 yehC Escherichia coli CFT073 fimbrial chaperone yehC NP_754525.1 2481598 R 199310 CDS NP_754526.1 26248486 1037964 complement(2482353..2482895) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2111; Escherichia coli O157:H7 ortholog: z3279; hypothetical protein 2482895 yehD 1037964 yehD Escherichia coli CFT073 hypothetical protein NP_754526.1 2482353 R 199310 CDS NP_754527.1 26248487 1037965 complement(2483231..2483740) 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 2483740 1037965 c2639 Escherichia coli CFT073 transposase NP_754527.1 2483231 R 199310 CDS NP_754528.1 26248488 1037966 complement(2483901..2484182) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2112; Escherichia coli O157:H7 ortholog: z3280; hypothetical protein 2484182 yehE 1037966 yehE Escherichia coli CFT073 hypothetical protein NP_754528.1 2483901 R 199310 CDS NP_754529.2 161486183 1037967 complement(2484445..2485554) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2113; Escherichia coli O157:H7 ortholog: z3281; ATPase 2485554 mrp 1037967 mrp Escherichia coli CFT073 ATPase NP_754529.2 2484445 R 199310 CDS NP_754530.1 26248490 1037968 2485677..2487719 1 NC_004431.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2487719 metG 1037968 metG Escherichia coli CFT073 methionyl-tRNA synthetase NP_754530.1 2485677 D 199310 CDS NP_754531.1 26248491 1037969 2487860..2491648 1 NC_004431.1 Fusion of Escherichia coli K-12 B2115 and B2116; Residues 313 to 949 of 1262 are 81.12 pct identical to residues 1 to 639 of 645 from MG1655 : b2116; hypothetical protein 2491648 1037969 c2643 Escherichia coli CFT073 hypothetical protein NP_754531.1 2487860 D 199310 CDS NP_754532.1 26248492 1037971 2491658..2495290 1 NC_004431.1 Escherichia coli K-12 ortholog: b2118; Escherichia coli O157:H7 ortholog: z3287; hypothetical protein 2495290 yehI 1037971 yehI Escherichia coli CFT073 hypothetical protein NP_754532.1 2491658 D 199310 CDS NP_754535.1 26248495 1037975 2495351..2495536 1 NC_004431.1 Residues 1 to 60 of 61 are 94.99 pct identical to residues 1 to 60 of 105 from GenPept.129 : >gb|AAA60479.1| (U00007) yehK [Escherichia coli]; hypothetical protein 2495536 1037975 c2647 Escherichia coli CFT073 hypothetical protein NP_754535.1 2495351 D 199310 CDS NP_754536.1 26248496 1037978 2495373..2495543 1 NC_004431.1 hypothetical protein 2495543 1037978 c2648 Escherichia coli CFT073 hypothetical protein NP_754536.1 2495373 D 199310 CDS NP_754537.1 26248497 1037981 2496233..2497387 1 NC_004431.1 Escherichia coli K-12 ortholog: b2119; Escherichia coli O157:H7 ortholog: z3291; hypothetical protein 2497387 yehL 1037981 yehL Escherichia coli CFT073 hypothetical protein NP_754537.1 2496233 D 199310 CDS NP_754538.1 26248498 1037982 2497323..2499677 1 NC_004431.1 Escherichia coli K-12 ortholog: b2120; Escherichia coli O157:H7 ortholog: z3292; hypothetical protein 2499677 yehM 1037982 yehM Escherichia coli CFT073 hypothetical protein NP_754538.1 2497323 D 199310 CDS NP_754539.1 26248499 1037983 2499607..2500806 1 NC_004431.1 Escherichia coli K-12 ortholog: b2121; Escherichia coli O157:H7 ortholog: z3294; hypothetical protein 2500806 yehP 1037983 yehP Escherichia coli CFT073 hypothetical protein NP_754539.1 2499607 D 199310 CDS NP_754540.1 26248500 1037985 2500803..2502806 1 NC_004431.1 Escherichia coli K-12 ortholog: b2122; Escherichia coli O157:H7 ortholog: z3295; hypothetical protein 2502806 yehQ 1037985 yehQ Escherichia coli CFT073 hypothetical protein NP_754540.1 2500803 D 199310 CDS NP_754541.1 26248501 1037987 2502919..2503392 1 NC_004431.1 Escherichia coli K-12 ortholog: b2123; Escherichia coli O157:H7 ortholog: z3300; lipoprotein yehR 2503392 yehR 1037987 yehR Escherichia coli CFT073 lipoprotein yehR NP_754541.1 2502919 D 199310 CDS NP_754542.1 26248502 1037988 complement(2503433..2503960) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2124; Escherichia coli O157:H7 ortholog: z3301; hypothetical protein 2503960 yehS 1037988 yehS Escherichia coli CFT073 hypothetical protein NP_754542.1 2503433 R 199310 CDS NP_754543.1 26248503 1037989 complement(2503950..2504684) 1 NC_004431.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2504684 yehT 1037989 yehT Escherichia coli CFT073 two-component response-regulatory protein YehT NP_754543.1 2503950 R 199310 CDS NP_754544.1 26248504 1037992 complement(2504666..2506366) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2126; Escherichia coli O157:H7 ortholog: z3303; hypothetical protein 2506366 yehU 1037992 yehU Escherichia coli CFT073 hypothetical protein NP_754544.1 2504666 R 199310 CDS NP_754545.1 26248505 1037994 2506573..2507304 1 NC_004431.1 Escherichia coli K-12 ortholog: b2127; Escherichia coli O157:H7 ortholog: z3376; MerR-like regulator A 2507304 yehV 1037994 yehV Escherichia coli CFT073 MerR-like regulator A NP_754545.1 2506573 D 199310 CDS NP_754546.1 26248506 1037996 complement(2507452..2508183) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2128; Escherichia coli O157:H7 ortholog: z3377; ABC transporter permease 2508183 yehW 1037996 yehW Escherichia coli CFT073 ABC transporter permease NP_754546.1 2507452 R 199310 CDS NP_754547.1 26248507 1037997 complement(2508188..2509114) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2129; Escherichia coli O157:H7 ortholog: z3378; ABC transporter ATP-binding protein 2509114 yehX 1037997 yehX Escherichia coli CFT073 ABC transporter ATP-binding protein NP_754547.1 2508188 R 199310 CDS NP_754548.1 26248508 1037998 complement(2509107..2510264) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2130; Escherichia coli O157:H7 ortholog: z3379; ABC transporter permease 2510264 yehY 1037998 yehY Escherichia coli CFT073 ABC transporter permease NP_754548.1 2509107 R 199310 CDS NP_754549.1 26248509 1038000 complement(2510271..2511188) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2131; Escherichia coli O157:H7 ortholog: z3380; hypothetical protein 2511188 yehZ 1038000 yehZ Escherichia coli CFT073 hypothetical protein NP_754549.1 2510271 R 199310 CDS NP_754550.1 26248510 1038002 complement(2511219..2511371) 1 NC_004431.1 hypothetical protein 2511371 1038002 c2662 Escherichia coli CFT073 hypothetical protein NP_754550.1 2511219 R 199310 CDS NP_754551.1 26248511 1038003 complement(2511378..2513675) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2132; Escherichia coli O157:H7 ortholog: z3381; periplasmic beta-glucosidase 2513675 bglX 1038003 bglX Escherichia coli CFT073 periplasmic beta-glucosidase NP_754551.1 2511378 R 199310 CDS NP_754552.2 161486182 1038004 2513871..2515586 1 NC_004431.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2515586 dld 1038004 dld Escherichia coli CFT073 D-lactate dehydrogenase NP_754552.2 2513871 D 199310 CDS NP_754553.1 26248513 1038005 complement(2515625..2516566) 1 NC_004431.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2516566 pbpG 1038005 pbpG Escherichia coli CFT073 D-alanyl-D-alanine endopeptidase NP_754553.1 2515625 R 199310 CDS NP_754554.1 26248514 1038006 complement(2516636..2516758) 1 NC_004431.1 hypothetical protein 2516758 1038006 c2666 Escherichia coli CFT073 hypothetical protein NP_754554.1 2516636 R 199310 CDS NP_754555.1 26248515 1038007 complement(2516731..2517342) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2135; Escherichia coli O157:H7 ortholog: z3384; hypothetical protein 2517342 yohC 1038007 yohC Escherichia coli CFT073 hypothetical protein NP_754555.1 2516731 R 199310 CDS NP_754556.1 26248516 1038008 2517452..2518066 1 NC_004431.1 Escherichia coli K-12 ortholog: b2136; Escherichia coli O157:H7 ortholog: z3385; hypothetical protein 2518066 yohD 1038008 yohD Escherichia coli CFT073 hypothetical protein NP_754556.1 2517452 D 199310 CDS NP_754557.1 26248517 1038009 complement(2518186..2518572) 1 NC_004431.1 Residues 1 to 128 of 128 are 97.65 pct identical to residues 126 to 253 of 253 from GenPept.129 : >gb|AAC75198.1| (AE000303) oxidoreductase [Escherichia coli K12]; hypothetical protein 2518572 1038009 c2669 Escherichia coli CFT073 hypothetical protein NP_754557.1 2518186 R 199310 CDS NP_754558.1 26248518 1038010 complement(2518639..2518947) 1 NC_004431.1 Residues 1 to 102 of 102 are 99.01 pct identical to residues 1 to 102 of 253 from MG1655 : b2137; hypothetical protein 2518947 1038010 c2670 Escherichia coli CFT073 hypothetical protein NP_754558.1 2518639 R 199310 CDS NP_754559.2 161486181 1038011 complement(2519000..2520436) 1 NC_004431.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2520436 yohG 1038011 yohG Escherichia coli CFT073 multidrug resistance outer membrane protein MdtQ NP_754559.2 2519000 R 199310 CDS NP_754560.1 26248520 1038012 complement(2521130..2522146) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2140; Escherichia coli O157:H7 ortholog: z3389; tRNA-dihydrouridine synthase C 2522146 yohI 1038012 yohI Escherichia coli CFT073 tRNA-dihydrouridine synthase C NP_754560.1 2521130 R 199310 CDS NP_754561.1 26248521 1038017 2522283..2522717 1 NC_004431.1 Escherichia coli K-12 ortholog: b2141; Escherichia coli O157:H7 ortholog: z3396; hypothetical protein 2522717 yohJ 1038017 yohJ Escherichia coli CFT073 hypothetical protein NP_754561.1 2522283 D 199310 CDS NP_754562.1 26248522 1038018 2522714..2523409 1 NC_004431.1 Escherichia coli K-12 ortholog: b2142; Escherichia coli O157:H7 ortholog: z3397; hypothetical protein 2523409 yohK 1038018 yohK Escherichia coli CFT073 hypothetical protein NP_754562.1 2522714 D 199310 CDS NP_754563.1 26248523 1038019 2523539..2524423 1 NC_004431.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2524423 cdd 1038019 cdd Escherichia coli CFT073 cytidine deaminase NP_754563.1 2523539 D 199310 CDS NP_754564.1 26248524 1038022 complement(2524268..2524396) 1 NC_004431.1 hypothetical protein 2524396 1038022 c2676 Escherichia coli CFT073 hypothetical protein NP_754564.1 2524268 R 199310 CDS NP_754565.1 26248525 1038023 2524573..2525292 1 NC_004431.1 Escherichia coli K-12 ortholog: b2144; Escherichia coli O157:H7 ortholog: z3399; hypothetical protein 2525292 sanA 1038023 sanA Escherichia coli CFT073 hypothetical protein NP_754565.1 2524573 D 199310 CDS NP_754566.1 26248526 1038024 2525295..2525534 1 NC_004431.1 Escherichia coli K-12 ortholog: b2145; Escherichia coli O157:H7 ortholog: z3400; hypothetical protein 2525534 yeiS 1038024 yeiS Escherichia coli CFT073 hypothetical protein NP_754566.1 2525295 D 199310 CDS NP_754567.1 26248527 1038025 2525728..2526966 1 NC_004431.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2526966 yeiT 1038025 yeiT Escherichia coli CFT073 oxidoreductase NP_754567.1 2525728 D 199310 CDS NP_754568.2 161486180 1038027 2526960..2528195 1 NC_004431.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2528195 yeiA 1038027 yeiA Escherichia coli CFT073 dihydropyrimidine dehydrogenase NP_754568.2 2526960 D 199310 CDS NP_754569.1 26248529 1038028 2528217..2528360 1 NC_004431.1 hypothetical protein 2528360 1038028 c2681 Escherichia coli CFT073 hypothetical protein NP_754569.1 2528217 D 199310 CDS NP_754570.1 26248530 1038030 complement(2528438..2529448) 1 NC_004431.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 2529448 mglC 1038030 mglC Escherichia coli CFT073 beta-methylgalactoside transporter inner membrane component NP_754570.1 2528438 R 199310 CDS NP_754571.1 26248531 1038032 complement(2529464..2530984) 1 NC_004431.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2530984 mglA 1038032 mglA Escherichia coli CFT073 galactose/methyl galaxtoside transporter ATP-binding protein NP_754571.1 2529464 R 199310 CDS NP_754572.1 26248532 1038033 complement(2531045..2532043) 1 NC_004431.1 GBP; Escherichia coli K-12 ortholog: b2150; Escherichia coli O157:H7 ortholog: z3405; D-galactose-binding periplasmic protein 2532043 mglB 1038033 mglB Escherichia coli CFT073 D-galactose-binding periplasmic protein NP_754572.1 2531045 R 199310 CDS NP_754573.1 26248533 1038035 complement(2532323..2533369) 1 NC_004431.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2533369 galS 1038035 galS Escherichia coli CFT073 DNA-binding transcriptional regulator GalS NP_754573.1 2532323 R 199310 CDS NP_754574.1 26248534 1038040 2533353..2533556 1 NC_004431.1 hypothetical protein 2533556 1038040 c2686 Escherichia coli CFT073 hypothetical protein NP_754574.1 2533353 D 199310 CDS NP_754575.1 26248535 1038046 complement(2533505..2534662) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2152; Escherichia coli O157:H7 ortholog: z3408; hypothetical protein 2534662 yeiB 1038046 yeiB Escherichia coli CFT073 hypothetical protein NP_754575.1 2533505 R 199310 CDS NP_754576.1 26248536 1038047 complement(2534679..2535347) 1 NC_004431.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2535347 folE 1038047 folE Escherichia coli CFT073 GTP cyclohydrolase I NP_754576.1 2534679 R 199310 CDS NP_754577.1 26248537 1038049 2535605..2536441 1 NC_004431.1 Escherichia coli K-12 ortholog: b2154; Escherichia coli O157:H7 ortholog: z3410; hypothetical protein 2536441 yeiG 1038049 yeiG Escherichia coli CFT073 hypothetical protein NP_754577.1 2535605 D 199310 CDS NP_754578.2 229106376 1038050 complement(2536473..2538464) 1 NC_004431.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2538464 cirA 1038050 cirA Escherichia coli CFT073 colicin I receptor NP_754578.2 2536473 R 199310 CDS NP_754579.1 26248539 1038051 complement(2538756..2540225) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2156; Escherichia coli O157:H7 ortholog: z3413; lysine transporter 2540225 lysP 1038051 lysP Escherichia coli CFT073 lysine transporter NP_754579.1 2538756 R 199310 CDS NP_754580.1 26248540 1038054 complement(2540430..2541311) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2157; Escherichia coli O157:H7 ortholog: z3414; DNA-binding transcriptional regulator 2541311 yeiE 1038054 yeiE Escherichia coli CFT073 DNA-binding transcriptional regulator NP_754580.1 2540430 R 199310 CDS NP_754581.1 26248541 1038057 2541410..2542459 1 NC_004431.1 Escherichia coli K-12 ortholog: b2158; Escherichia coli O157:H7 ortholog: z3415; hypothetical protein 2542459 yeiH 1038057 yeiH Escherichia coli CFT073 hypothetical protein NP_754581.1 2541410 D 199310 CDS NP_754582.1 26248542 1038059 2542533..2543390 1 NC_004431.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2543390 nfo 1038059 nfo Escherichia coli CFT073 endonuclease IV NP_754582.1 2542533 D 199310 CDS NP_754583.1 26248543 1038060 2543394..2544482 1 NC_004431.1 Escherichia coli K-12 ortholog: b2160; Escherichia coli O157:H7 ortholog: z3417; hypothetical protein 2544482 yeiI 1038060 yeiI Escherichia coli CFT073 hypothetical protein NP_754583.1 2543394 D 199310 CDS NP_754584.1 26248544 1038061 complement(2544750..2545691) 1 NC_004431.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2545691 rihB 1038061 rihB Escherichia coli CFT073 ribonucleoside hydrolase 2 NP_754584.1 2544750 R 199310 CDS NP_754585.1 26248545 1038064 2545821..2546519 1 NC_004431.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2546519 yeiL 1038064 yeiL Escherichia coli CFT073 DNA-binding transcriptional activator YeiL NP_754585.1 2545821 D 199310 CDS NP_754586.1 26248546 1038065 complement(2546586..2547836) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2164; Escherichia coli O157:H7 ortholog: z3421; transport protein YeiM 2547836 yeiM 1038065 yeiM Escherichia coli CFT073 transport protein YeiM NP_754586.1 2546586 R 199310 CDS NP_754587.1 26248547 1038072 complement(2548858..2549913) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2166; Escherichia coli O157:H7 ortholog: z3423; hypothetical protein 2549913 yeiC 1038072 yeiC Escherichia coli CFT073 hypothetical protein NP_754587.1 2548858 R 199310 CDS NP_754588.1 26248548 1038073 complement(2550255..2551946) 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 2551946 fruA 1038073 fruA Escherichia coli CFT073 PTS system fructose-specific transporter subunits IIBC NP_754588.1 2550255 R 199310 CDS NP_754589.1 26248549 1038075 complement(2551963..2552901) 1 NC_004431.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2552901 fruK 1038075 fruK Escherichia coli CFT073 1-phosphofructokinase NP_754589.1 2551963 R 199310 CDS NP_754590.1 26248550 1038076 complement(2552901..2554031) 1 NC_004431.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2554031 fruB 1038076 fruB Escherichia coli CFT073 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein NP_754590.1 2552901 R 199310 CDS NP_754591.1 26248551 1038077 2554196..2554327 1 NC_004431.1 hypothetical protein 2554327 1038077 c2705 Escherichia coli CFT073 hypothetical protein NP_754591.1 2554196 D 199310 CDS NP_754592.1 26248552 1038078 2554398..2555579 1 NC_004431.1 Escherichia coli K-12 ortholog: b2170; Escherichia coli O157:H7 ortholog: z3428; sugar efflux transporter B 2555579 yeiO 1038078 yeiO Escherichia coli CFT073 sugar efflux transporter B NP_754592.1 2554398 D 199310 CDS NP_754593.1 26248553 1038079 complement(2555576..2555764) 1 NC_004431.1 Residues 1 to 62 of 62 are 100.00 pct identical to residues 23 to 84 of 84 from SwissProt.40 : >sp|P58039|YEIW_ECOLI Hypothetical protein yeiW; hypothetical protein 2555764 1038079 c2707 Escherichia coli CFT073 hypothetical protein NP_754593.1 2555576 R 199310 CDS NP_754594.2 161486179 1038080 2555985..2556557 1 NC_004431.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2556557 yeiP 1038080 yeiP Escherichia coli CFT073 elongation factor P NP_754594.2 2555985 D 199310 CDS NP_754595.1 26248555 1038083 2556771..2558246 1 NC_004431.1 Escherichia coli K-12 ortholog: b2172; Escherichia coli O157:H7 ortholog: z3431; oxidoreductase yeiQ 2558246 yeiQ 1038083 yeiQ Escherichia coli CFT073 oxidoreductase yeiQ NP_754595.1 2556771 D 199310 CDS NP_754596.1 26248556 1038085 2558364..2559350 1 NC_004431.1 Escherichia coli K-12 ortholog: b2173; Escherichia coli O157:H7 ortholog: z3432; hypothetical protein 2559350 yeiR 1038085 yeiR Escherichia coli CFT073 hypothetical protein NP_754596.1 2558364 D 199310 CDS NP_754597.1 26248557 1038091 2559353..2560102 1 NC_004431.1 Escherichia coli K-12 ortholog: b2174; Escherichia coli O157:H7 ortholog: z3433; hypothetical protein 2560102 yeiU 1038091 yeiU Escherichia coli CFT073 hypothetical protein NP_754597.1 2559353 D 199310 CDS NP_754598.1 26248558 1038092 2560514..2561080 1 NC_004431.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2561080 spr 1038092 spr Escherichia coli CFT073 outer membrane lipoprotein NP_754598.1 2560514 D 199310 CDS NP_754599.1 26248559 1038093 2561261..2562817 1 NC_004431.1 Escherichia coli K-12 ortholog: b2176; Escherichia coli O157:H7 ortholog: z3435; hypothetical protein 2562817 rtn 1038093 rtn Escherichia coli CFT073 hypothetical protein NP_754599.1 2561261 D 199310 CDS NP_754600.3 347357889 1038094 2562893..2564713 1 NC_004431.1 Escherichia coli K-12 ortholog: b2177; Escherichia coli O157:H7 ortholog: z3436; hypothetical protein 2564713 yejA 1038094 yejA Escherichia coli CFT073 hypothetical protein NP_754600.3 2562893 D 199310 CDS NP_754601.1 26248561 1038098 2564714..2565808 1 NC_004431.1 Escherichia coli K-12 ortholog: b2178; Escherichia coli O157:H7 ortholog: z3437; ABC transporter permease 2565808 yejB 1038098 yejB Escherichia coli CFT073 ABC transporter permease NP_754601.1 2564714 D 199310 CDS NP_754602.1 26248562 1038107 2565808..2566833 1 NC_004431.1 Escherichia coli K-12 ortholog: b2179; Escherichia coli O157:H7 ortholog: z3438; ABC transporter permease 2566833 yejE 1038107 yejE Escherichia coli CFT073 ABC transporter permease NP_754602.1 2565808 D 199310 CDS NP_754603.1 26248563 1038108 2566835..2568424 1 NC_004431.1 Escherichia coli K-12 ortholog: b2180; Escherichia coli O157:H7 ortholog: z3439; ABC transporter ATP-binding protein 2568424 yejF 1038108 yejF Escherichia coli CFT073 ABC transporter ATP-binding protein NP_754603.1 2566835 D 199310 CDS NP_754604.1 26248564 1038109 complement(2568428..2568772) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2181; Escherichia coli O157:H7 ortholog: z3440; hypothetical protein 2568772 yejG 1038109 yejG Escherichia coli CFT073 hypothetical protein NP_754604.1 2568428 R 199310 CDS NP_754605.1 26248565 1038111 complement(2569106..2570296) 1 NC_004431.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 2570296 bcr 1038111 bcr Escherichia coli CFT073 bicyclomycin/multidrug efflux system NP_754605.1 2569106 R 199310 CDS NP_754606.3 347357888 1038113 complement(2570324..2571115) 1 NC_004431.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2571115 rsuA 1038113 rsuA Escherichia coli CFT073 16S rRNA pseudouridylate synthase A NP_754606.3 2570324 R 199310 CDS NP_754607.1 26248567 1038117 2571169..2572929 1 NC_004431.1 Escherichia coli K-12 ortholog: b2184; Escherichia coli O157:H7 ortholog: z3443; hypothetical protein 2572929 yejH 1038117 yejH Escherichia coli CFT073 hypothetical protein NP_754607.1 2571169 D 199310 CDS NP_754609.1 26248569 1038124 complement(2573039..2573470) 1 NC_004431.1 hypothetical protein 2573470 1038124 c2723 Escherichia coli CFT073 hypothetical protein NP_754609.1 2573039 R 199310 CDS NP_754608.2 161486176 1038122 2573054..2573338 1 NC_004431.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2573338 rplY 1038122 rplY Escherichia coli CFT073 50S ribosomal protein L25 NP_754608.2 2573054 D 199310 CDS NP_754610.1 26248570 1038125 complement(2573477..2574484) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2186; Escherichia coli O157:H7 ortholog: z3445; nucleoid-associated protein NdpA 2574484 yejK 1038125 yejK Escherichia coli CFT073 nucleoid-associated protein NdpA NP_754610.1 2573477 R 199310 CDS NP_754611.1 26248571 1038128 2574666..2574893 1 NC_004431.1 Escherichia coli K-12 ortholog: b2187; Escherichia coli O157:H7 ortholog: z3446; hypothetical protein 2574893 yejL 1038128 yejL Escherichia coli CFT073 hypothetical protein NP_754611.1 2574666 D 199310 CDS NP_754612.1 26248572 1038130 2574913..2576673 1 NC_004431.1 Escherichia coli K-12 ortholog: b2188; Escherichia coli O157:H7 ortholog: z3447; hypothetical protein 2576673 yejM 1038130 yejM Escherichia coli CFT073 hypothetical protein NP_754612.1 2574913 D 199310 CDS NP_754613.1 26248573 1038135 complement(2576926..2577081) 1 NC_004431.1 Residues 1 to 42 of 51 are 97.61 pct identical to residues 575 to 616 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein 2577081 1038135 c2727 Escherichia coli CFT073 hypothetical protein NP_754613.1 2576926 R 199310 CDS NP_754614.1 26248574 1038136 complement(2577062..2577190) 1 NC_004431.1 Residues 3 to 35 of 42 are 100.00 pct identical to residues 536 to 568 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein 2577190 1038136 c2728 Escherichia coli CFT073 hypothetical protein NP_754614.1 2577062 R 199310 CDS NP_754615.1 26248575 1038137 complement(2577163..2577552) 1 NC_004431.1 Residues 53 to 81 of 129 are 89.65 pct identical to residues 465 to 493 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein 2577552 1038137 c2729 Escherichia coli CFT073 hypothetical protein NP_754615.1 2577163 R 199310 CDS NP_754616.1 26248576 1038138 2578154..2578831 1 NC_004431.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2578831 narP 1038138 narP Escherichia coli CFT073 transcriptional regulator NarP NP_754616.1 2578154 D 199310 CDS NP_754617.1 26248577 1038140 complement(2578866..2579918) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2194; Escherichia coli O157:H7 ortholog: z3451; cytochrome c-type biogenesis protein ccmH 2579918 ccmH 1038140 ccmH Escherichia coli CFT073 cytochrome c-type biogenesis protein ccmH NP_754617.1 2578866 R 199310 CDS NP_754618.1 26248578 1038141 complement(2579915..2580472) 1 NC_004431.1 Cytochrome c biogenesis protein ccmG; Escherichia coli K-12 ortholog: b2195; Escherichia coli O157:H7 ortholog: z3452; Thiol:disulfide interchange protein dsbE 2580472 dsbE 1038141 dsbE Escherichia coli CFT073 Thiol:disulfide interchange protein dsbE NP_754618.1 2579915 R 199310 CDS NP_754619.1 26248579 1038142 complement(2580469..2582412) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2196; Escherichia coli O157:H7 ortholog: z3453; cytochrome c-type biogenesis protein ccmF 2582412 ccmF 1038142 ccmF Escherichia coli CFT073 cytochrome c-type biogenesis protein ccmF NP_754619.1 2580469 R 199310 CDS NP_754620.1 26248580 1038144 complement(2582409..2582888) 1 NC_004431.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2582888 ccmE 1038144 ccmE Escherichia coli CFT073 cytochrome c-type biogenesis protein CcmE NP_754620.1 2582409 R 199310 CDS NP_754621.1 26248581 1038146 complement(2582885..2583094) 1 NC_004431.1 Cytochrome c-type biogenesis protein ccmD; Escherichia coli K-12 ortholog: b2198; Escherichia coli O157:H7 ortholog: z3455; Heme exporter protein D 2583094 ccmD 1038146 ccmD Escherichia coli CFT073 Heme exporter protein D NP_754621.1 2582885 R 199310 CDS NP_754622.1 26248582 1038147 complement(2583091..2583852) 1 NC_004431.1 Cytochrome c-type biogenesis protein ccmC; Escherichia coli K-12 ortholog: b2199; Escherichia coli O157:H7 ortholog: z3456; Heme exporter protein C 2583852 ccmC 1038147 ccmC Escherichia coli CFT073 Heme exporter protein C NP_754622.1 2583091 R 199310 CDS NP_754623.1 26248583 1038148 complement(2583870..2584532) 1 NC_004431.1 Cytochrome c-type biogenesis protein ccmB; Escherichia coli K-12 ortholog: b2200; Escherichia coli O157:H7 ortholog: z3457; Heme exporter protein B 2584532 ccmB 1038148 ccmB Escherichia coli CFT073 Heme exporter protein B NP_754623.1 2583870 R 199310 CDS NP_754624.1 26248584 1038149 complement(2584529..2585152) 1 NC_004431.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2585152 ccmA 1038149 ccmA Escherichia coli CFT073 cytochrome c biogenesis protein CcmA NP_754624.1 2584529 R 199310 CDS NP_754625.1 26248585 1038151 complement(2585165..2585767) 1 NC_004431.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2585767 napC 1038151 napC Escherichia coli CFT073 cytochrome c-type protein NapC NP_754625.1 2585165 R 199310 CDS NP_754626.1 26248586 1038152 2585204..2585797 1 NC_004431.1 hypothetical protein 2585797 1038152 c2740 Escherichia coli CFT073 hypothetical protein NP_754626.1 2585204 D 199310 CDS NP_754627.2 161486175 1038153 complement(2585777..2586226) 1 NC_004431.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2586226 napB 1038153 napB Escherichia coli CFT073 citrate reductase cytochrome c-type subunit NP_754627.2 2585777 R 199310 CDS NP_754628.1 26248588 1038157 2585846..2586388 1 NC_004431.1 hypothetical protein 2586388 1038157 c2742 Escherichia coli CFT073 hypothetical protein NP_754628.1 2585846 D 199310 CDS NP_754629.1 26248589 1038161 complement(2586223..2587086) 1 NC_004431.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2587086 napH 1038161 napH Escherichia coli CFT073 quinol dehydrogenase membrane component NP_754629.1 2586223 R 199310 CDS NP_754630.1 26248590 1038162 complement(2587073..2587768) 1 NC_004431.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2587768 napG 1038162 napG Escherichia coli CFT073 quinol dehydrogenase periplasmic component NP_754630.1 2587073 R 199310 CDS NP_754631.1 26248591 1038163 complement(2587775..2590261) 1 NC_004431.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2590261 napA 1038163 napA Escherichia coli CFT073 nitrate reductase catalytic subunit NP_754631.1 2587775 R 199310 CDS NP_754632.1 26248592 1038165 complement(2590258..2590521) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2207; Escherichia coli O157:H7 ortholog: z3464; assembly protein for periplasmic nitrate reductase 2590521 napD 1038165 napD Escherichia coli CFT073 assembly protein for periplasmic nitrate reductase NP_754632.1 2590258 R 199310 CDS NP_754633.1 26248593 1038166 complement(2590511..2591005) 1 NC_004431.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2591005 napF 1038166 napF Escherichia coli CFT073 ferredoxin-type protein NP_754633.1 2590511 R 199310 CDS NP_754634.1 26248594 1038167 2591105..2591278 1 NC_004431.1 hypothetical protein 2591278 1038167 c2748 Escherichia coli CFT073 hypothetical protein NP_754634.1 2591105 D 199310 CDS NP_754635.1 26248595 1038168 complement(2591198..2591326) 1 NC_004431.1 hypothetical protein 2591326 1038168 c2749 Escherichia coli CFT073 hypothetical protein NP_754635.1 2591198 R 199310 CDS NP_754636.1 26248596 1038169 2591392..2591901 1 NC_004431.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2591901 eco 1038169 eco Escherichia coli CFT073 ecotin NP_754636.1 2591392 D 199310 CDS NP_754637.1 26248597 1038170 complement(2592051..2593697) 1 NC_004431.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2593697 yojH 1038170 yojH Escherichia coli CFT073 malate:quinone oxidoreductase NP_754637.1 2592051 R 199310 CDS NP_754638.1 26248598 1038174 complement(2593915..2595558) 1 NC_004431.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding component 2595558 yojI 1038174 yojI Escherichia coli CFT073 multidrug transporter membrane component/ATP-binding component NP_754638.1 2593915 R 199310 CDS NP_754639.1 26248599 1038177 complement(2595634..2596284) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2212; Escherichia coli O157:H7 ortholog: z3470; alkylated DNA repair protein AlkB 2596284 alkB 1038177 alkB Escherichia coli CFT073 alkylated DNA repair protein AlkB NP_754639.1 2595634 R 199310 CDS NP_754640.1 26248600 1038183 complement(2596284..2597348) 1 NC_004431.1 Regulatory protein of adaptative response; Escherichia coli K-12 ortholog: b2213; Escherichia coli O157:H7 ortholog: z3471; bifunctional; ADA regulatory protein 2597348 ada 1038183 ada Escherichia coli CFT073 ADA regulatory protein NP_754640.1 2596284 R 199310 CDS NP_754641.1 26248601 1038184 2597082..2597300 1 NC_004431.1 Residues 8 to 56 of 72 are 77.55 pct identical to residues 1 to 49 of 117 from GenPept.129 : >dbj|BAB47178.1| (AB058960) inverted ada-Golga3 fusion protein [Mus musculus]; hypothetical protein 2597300 1038184 c2755 Escherichia coli CFT073 hypothetical protein NP_754641.1 2597082 D 199310 CDS NP_754642.1 26248602 1038186 complement(2597422..2598477) 1 NC_004431.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2598477 yojL 1038186 yojL Escherichia coli CFT073 thiamine biosynthesis lipoprotein ApbE NP_754642.1 2597422 R 199310 CDS NP_754643.1 26248603 1038187 2598529..2599623 1 NC_004431.1 Residues 20 to 72 of 364 are 60.37 pct identical to residues 16 to 68 of 69 from GenPept.129 : >gb|AAA32302.1| (J02580) ORF1 [Bacteriophage PA-2]; hypothetical protein 2599623 1038187 c2757 Escherichia coli CFT073 hypothetical protein NP_754643.1 2598529 D 199310 CDS NP_754644.1 26248604 1038188 complement(2598589..2599716) 1 NC_004431.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2599716 ompC 1038188 ompC Escherichia coli CFT073 outer membrane porin protein C NP_754644.1 2598589 R 199310 CDS NP_754645.1 26248605 1038191 2600455..2603127 1 NC_004431.1 Escherichia coli K-12 ortholog: b2216; Escherichia coli O157:H7 ortholog: z3475; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2603127 yojN 1038191 yojN Escherichia coli CFT073 phosphotransfer intermediate protein in two-component regulatory system with RcsBC NP_754645.1 2600455 D 199310 CDS NP_754646.1 26248606 1038196 2603099..2603794 1 NC_004431.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2603794 rcsB 1038196 rcsB Escherichia coli CFT073 transcriptional regulator RcsB NP_754646.1 2603099 D 199310 CDS NP_754647.1 26248607 1038197 complement(2603880..2606729) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2218; Escherichia coli O157:H7 ortholog: z3477; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2606729 rcsC 1038197 rcsC Escherichia coli CFT073 hybrid sensory kinase in two-component regulatory system with RcsB and YojN NP_754647.1 2603880 R 199310 CDS NP_754648.1 26248608 1038209 2606884..2608722 1 NC_004431.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2608722 atoS 1038209 atoS Escherichia coli CFT073 sensory histidine kinase AtoS NP_754648.1 2606884 D 199310 CDS NP_754649.1 26248609 1038223 2608719..2610104 1 NC_004431.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2610104 atoC 1038223 atoC Escherichia coli CFT073 acetoacetate metabolism regulatory protein AtoC NP_754649.1 2608719 D 199310 CDS NP_754650.1 26248610 1038225 2610300..2610962 1 NC_004431.1 Escherichia coli K-12 ortholog: b2221; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2610962 atoD 1038225 atoD Escherichia coli CFT073 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha NP_754650.1 2610300 D 199310 CDS NP_754651.1 26248611 1038227 2610962..2611612 1 NC_004431.1 Escherichia coli K-12 ortholog: b2222; acetate CoA-transferase beta subunit 2611612 atoA 1038227 atoA Escherichia coli CFT073 acetate CoA-transferase beta subunit NP_754651.1 2610962 D 199310 CDS NP_754652.1 26248612 1038247 2611609..2612931 1 NC_004431.1 Escherichia coli K-12 ortholog: b2223; Short-chain fatty acids transporter 2612931 atoE 1038247 atoE Escherichia coli CFT073 Short-chain fatty acids transporter NP_754652.1 2611609 D 199310 CDS NP_754653.1 26248613 1038272 2612962..2614146 1 NC_004431.1 Escherichia coli K-12 ortholog: b2224; Escherichia coli O157:H7 ortholog: z4164; Acetyl-CoA acetyltransferase 2614146 atoB 1038272 atoB Escherichia coli CFT073 Acetyl-CoA acetyltransferase NP_754653.1 2612962 D 199310 CDS NP_754654.1 26248614 1038273 complement(2614220..2614996) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2225; Escherichia coli O157:H7 ortholog: z3478; hypothetical protein 2614996 yfaP 1038273 yfaP Escherichia coli CFT073 hypothetical protein NP_754654.1 2614220 R 199310 CDS NP_754655.1 26248615 1038275 complement(2615001..2616650) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2226; hypothetical protein 2616650 yfaQ 1038275 yfaQ Escherichia coli CFT073 hypothetical protein NP_754655.1 2615001 R 199310 CDS NP_754656.1 26248616 1038276 complement(2616651..2621180) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2228; Escherichia coli O157:H7 ortholog: z3481; hypothetical protein 2621180 1038276 c2770 Escherichia coli CFT073 hypothetical protein NP_754656.1 2616651 R 199310 CDS NP_754657.3 347357887 1038279 complement(2621189..2621839) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2229; Escherichia coli O157:H7 ortholog: z3482; hypothetical protein 2621839 yfaT 1038279 yfaT Escherichia coli CFT073 hypothetical protein NP_754657.3 2621189 R 199310 CDS NP_754658.3 347357886 1038280 complement(2621809..2623545) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2230; Escherichia coli O157:H7 ortholog: z3483; hypothetical protein 2623545 yfaA 1038280 yfaA Escherichia coli CFT073 hypothetical protein NP_754658.3 2621809 R 199310 CDS NP_754659.1 26248619 1038282 complement(2623646..2626273) 1 NC_004431.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2626273 gyrA 1038282 gyrA Escherichia coli CFT073 DNA gyrase subunit A NP_754659.1 2623646 R 199310 CDS NP_754660.1 26248620 1038283 2626420..2627142 1 NC_004431.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2627142 ubiG 1038283 ubiG Escherichia coli CFT073 3-demethylubiquinone-9 3-methyltransferase NP_754660.1 2626420 D 199310 CDS NP_754661.1 26248621 1038285 complement(2627282..2631046) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2233; Escherichia coli O157:H7 ortholog: z3487; adhesin 2631046 yfaL 1038285 yfaL Escherichia coli CFT073 adhesin NP_754661.1 2627282 R 199310 CDS NP_754662.1 26248622 1038290 2631722..2634007 1 NC_004431.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2634007 nrdA 1038290 nrdA Escherichia coli CFT073 ribonucleotide-diphosphate reductase subunit alpha NP_754662.1 2631722 D 199310 CDS NP_754663.1 26248623 1038291 2634197..2635327 1 NC_004431.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2635327 nrdB 1038291 nrdB Escherichia coli CFT073 ribonucleotide-diphosphate reductase subunit beta NP_754663.1 2634197 D 199310 CDS NP_754664.1 26248624 1038293 2635327..2635581 1 NC_004431.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2635581 yfaE 1038293 yfaE Escherichia coli CFT073 2Fe-2S ferredoxin NP_754664.1 2635327 D 199310 CDS NP_754665.1 26248625 1038295 complement(2635635..2636285) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2237; Escherichia coli O157:H7 ortholog: z3493; hypothetical protein 2636285 inaA 1038295 inaA Escherichia coli CFT073 hypothetical protein NP_754665.1 2635635 R 199310 CDS NP_754666.1 26248626 1038296 complement(2636488..2637564) 1 NC_004431.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2637564 glpQ 1038296 glpQ Escherichia coli CFT073 glycerophosphodiester phosphodiesterase NP_754666.1 2636488 R 199310 CDS NP_754667.1 26248627 1038297 complement(2637569..2638927) 1 NC_004431.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2638927 glpT 1038297 glpT Escherichia coli CFT073 sn-glycerol-3-phosphate transporter NP_754667.1 2637569 R 199310 CDS NP_754668.1 26248628 1038298 2639200..2640828 1 NC_004431.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2640828 glpA 1038298 glpA Escherichia coli CFT073 sn-glycerol-3-phosphate dehydrogenase subunit A NP_754668.1 2639200 D 199310 CDS NP_754669.1 26248629 1038299 2640746..2642077 1 NC_004431.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2642077 glpB 1038299 glpB Escherichia coli CFT073 anaerobic glycerol-3-phosphate dehydrogenase subunit B NP_754669.1 2640746 D 199310 CDS NP_754670.2 161486173 1038304 2642074..2643264 1 NC_004431.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2643264 glpC 1038304 glpC Escherichia coli CFT073 sn-glycerol-3-phosphate dehydrogenase subunit C NP_754670.2 2642074 D 199310 CDS NP_754671.1 26248631 1038305 2643289..2643414 1 NC_004431.1 hypothetical protein 2643414 1038305 c2785 Escherichia coli CFT073 hypothetical protein NP_754671.1 2643289 D 199310 CDS NP_754672.1 26248632 1038306 2643457..2644383 1 NC_004431.1 Escherichia coli K-12 ortholog: b2244; Escherichia coli O157:H7 ortholog: z3502; hypothetical protein 2644383 yfaD 1038306 yfaD Escherichia coli CFT073 hypothetical protein NP_754672.1 2643457 D 199310 CDS NP_754673.1 26248633 1038307 complement(2644424..2645227) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2245; Escherichia coli O157:H7 ortholog: z3503; aldolase 2645227 yfaU 1038307 yfaU Escherichia coli CFT073 aldolase NP_754673.1 2644424 R 199310 CDS NP_754674.1 26248634 1038308 complement(2645245..2646573) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2246; Escherichia coli O157:H7 ortholog: z3504; transport protein YfaV 2646573 yfaV 1038308 yfaV Escherichia coli CFT073 transport protein YfaV NP_754674.1 2645245 R 199310 CDS NP_754675.1 26248635 1038311 complement(2646591..2647808) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2247; Escherichia coli O157:H7 ortholog: z3505; hypothetical protein 2647808 yfaW 1038311 yfaW Escherichia coli CFT073 hypothetical protein NP_754675.1 2646591 R 199310 CDS NP_754676.1 26248636 1038312 complement(2647811..2648593) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2248; Escherichia coli O157:H7 ortholog: z3506; transcriptional regulator YfaX 2648593 yfaX 1038312 yfaX Escherichia coli CFT073 transcriptional regulator YfaX NP_754676.1 2647811 R 199310 CDS NP_754677.1 26248637 1038313 complement(2648813..2650015) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2249; Escherichia coli O157:H7 ortholog: z3507; competence damage-inducible protein A 2650015 1038313 c2791 Escherichia coli CFT073 competence damage-inducible protein A NP_754677.1 2648813 R 199310 CDS NP_754678.1 26248638 1038314 complement(2650115..2650678) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2250; Escherichia coli O157:H7 ortholog: z3508; hypothetical protein 2650678 yfaZ 1038314 yfaZ Escherichia coli CFT073 hypothetical protein NP_754678.1 2650115 R 199310 CDS NP_754679.1 26248639 1038316 2650936..2651361 1 NC_004431.1 Escherichia coli K-12 ortholog: b2251; Escherichia coli O157:H7 ortholog: z3509; Nudix hydrolase yfaO 2651361 yfaO 1038316 yfaO Escherichia coli CFT073 Nudix hydrolase yfaO NP_754679.1 2650936 D 199310 CDS NP_754680.1 26248640 1038317 complement(2651400..2652029) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2252; Escherichia coli O157:H7 ortholog: z3510; Ais protein 2652029 ais 1038317 ais Escherichia coli CFT073 Ais protein NP_754680.1 2651400 R 199310 CDS NP_754681.2 161486172 1038318 2652310..2653449 1 NC_004431.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2653449 yfbE 1038318 yfbE Escherichia coli CFT073 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase NP_754681.2 2652310 D 199310 CDS NP_754682.1 26248642 1038319 2653453..2654421 1 NC_004431.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2654421 1038319 c2796 Escherichia coli CFT073 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase NP_754682.1 2653453 D 199310 CDS NP_754683.1 26248643 1038320 2654421..2656403 1 NC_004431.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2656403 yfbG 1038320 yfbG Escherichia coli CFT073 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase NP_754683.1 2654421 D 199310 CDS NP_754684.1 26248644 1038323 2656400..2657290 1 NC_004431.1 Escherichia coli K-12 ortholog: b2256; Escherichia coli O157:H7 ortholog: z3514; hypothetical protein 2657290 yfbH 1038323 yfbH Escherichia coli CFT073 hypothetical protein NP_754684.1 2656400 D 199310 CDS NP_754685.1 26248645 1038324 2657290..2658942 1 NC_004431.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2658942 arnT 1038324 arnT Escherichia coli CFT073 4-amino-4-deoxy-L-arabinose transferase NP_754685.1 2657290 D 199310 CDS NP_754686.1 26248646 1038325 2658939..2659274 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3516; hypothetical protein 2659274 1038325 c2800 Escherichia coli CFT073 hypothetical protein NP_754686.1 2658939 D 199310 CDS NP_754687.2 161486171 1038326 2659274..2659660 1 NC_004431.1 Escherichia coli K-12 ortholog: b2258; Escherichia coli O157:H7 ortholog: z3517; hypothetical protein 2659660 yfbJ 1038326 yfbJ Escherichia coli CFT073 hypothetical protein NP_754687.2 2659274 D 199310 CDS NP_754688.1 26248648 1038329 complement(2659654..2659950) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2259; Escherichia coli O157:H7 ortholog: z3519; polymyxin B resistance protein pmrD 2659950 pmrD 1038329 pmrD Escherichia coli CFT073 polymyxin B resistance protein pmrD NP_754688.1 2659654 R 199310 CDS NP_754689.1 26248649 1038331 complement(2660030..2661385) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2260; Escherichia coli O157:H7 ortholog: z3520; O-succinylbenzoic acid--CoA ligase 2661385 menE 1038331 menE Escherichia coli CFT073 O-succinylbenzoic acid--CoA ligase NP_754689.1 2660030 R 199310 CDS NP_754690.1 26248650 1038332 complement(2661382..2662344) 1 NC_004431.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2662344 menC 1038332 menC Escherichia coli CFT073 O-succinylbenzoate synthase NP_754690.1 2661382 R 199310 CDS NP_754691.1 26248651 1038333 complement(2662344..2663201) 1 NC_004431.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2663201 menB 1038333 menB Escherichia coli CFT073 naphthoate synthase NP_754691.1 2662344 R 199310 CDS NP_754692.1 26248652 1038334 2662533..2663366 1 NC_004431.1 hypothetical protein 2663366 1038334 c2806 Escherichia coli CFT073 hypothetical protein NP_754692.1 2662533 D 199310 CDS NP_754693.1 26248653 1038335 complement(2663216..2663974) 1 NC_004431.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 2663974 yfbB 1038335 yfbB Escherichia coli CFT073 acyl-CoA thioester hydrolase NP_754693.1 2663216 R 199310 CDS NP_754694.2 161486170 1038336 complement(2663971..2665641) 1 NC_004431.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2665641 menD 1038336 menD Escherichia coli CFT073 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase NP_754694.2 2663971 R 199310 CDS NP_754695.1 26248655 1038337 complement(2665730..2667025) 1 NC_004431.1 synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase 2667025 menF 1038337 menF Escherichia coli CFT073 menaquinone-specific isochorismate synthase NP_754695.1 2665730 R 199310 CDS NP_754696.1 26248656 1038338 complement(2667104..2667409) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2266; Escherichia coli O157:H7 ortholog: z3526; hypothetical protein 2667409 elaB 1038338 elaB Escherichia coli CFT073 hypothetical protein NP_754696.1 2667104 R 199310 CDS NP_754697.1 26248657 1038339 complement(2667464..2667925) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2267; Escherichia coli O157:H7 ortholog: z3527; hypothetical protein 2667925 elaA 1038339 elaA Escherichia coli CFT073 hypothetical protein NP_754697.1 2667464 R 199310 CDS NP_754698.1 26248658 1038340 2667990..2668907 1 NC_004431.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2668907 elaC 1038340 elaC Escherichia coli CFT073 ribonuclease Z NP_754698.1 2667990 D 199310 CDS NP_754699.1 26248659 1038344 complement(2669028..2670770) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2270; hypothetical protein 2670770 yfbK 1038344 yfbK Escherichia coli CFT073 hypothetical protein NP_754699.1 2669028 R 199310 CDS NP_754700.1 26248660 1038345 2670902..2671024 1 NC_004431.1 hypothetical protein 2671024 1038345 c2814 Escherichia coli CFT073 hypothetical protein NP_754700.1 2670902 D 199310 CDS NP_754701.1 26248661 1038347 2671062..2671880 1 NC_004431.1 Escherichia coli K-12 ortholog: b2271; hypothetical protein 2671880 yfbL 1038347 yfbL Escherichia coli CFT073 hypothetical protein NP_754701.1 2671062 D 199310 CDS NP_754702.1 26248662 1038349 2671983..2672486 1 NC_004431.1 Escherichia coli K-12 ortholog: b2272; Escherichia coli O157:H7 ortholog: z3533; hypothetical protein 2672486 yfbM 1038349 yfbM Escherichia coli CFT073 hypothetical protein NP_754702.1 2671983 D 199310 CDS NP_754703.1 26248663 1038351 complement(2672553..2674010) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2674010 nuoN 1038351 nuoN Escherichia coli CFT073 NADH dehydrogenase subunit N NP_754703.1 2672553 R 199310 CDS NP_754704.1 26248664 1038352 complement(2674017..2675546) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2675546 nuoM 1038352 nuoM Escherichia coli CFT073 NADH dehydrogenase subunit M NP_754704.1 2674017 R 199310 CDS NP_754705.1 26248665 1038353 complement(2675710..2677551) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2677551 nuoL 1038353 nuoL Escherichia coli CFT073 NADH dehydrogenase subunit L NP_754705.1 2675710 R 199310 CDS NP_754706.1 26248666 1038357 complement(2677548..2677850) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2677850 nuoK 1038357 nuoK Escherichia coli CFT073 NADH dehydrogenase subunit K NP_754706.1 2677548 R 199310 CDS NP_754707.1 26248667 1038358 complement(2677847..2678401) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2678401 nuoJ 1038358 nuoJ Escherichia coli CFT073 NADH dehydrogenase subunit J NP_754707.1 2677847 R 199310 CDS NP_754708.1 26248668 1038361 complement(2678413..2678955) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2678955 nuoI 1038361 nuoI Escherichia coli CFT073 NADH dehydrogenase subunit I NP_754708.1 2678413 R 199310 CDS NP_754709.1 26248669 1038362 complement(2678970..2679947) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2679947 nuoH 1038362 nuoH Escherichia coli CFT073 NADH dehydrogenase subunit H NP_754709.1 2678970 R 199310 CDS NP_754710.1 26248670 1038363 complement(2679944..2682676) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2682676 nuoG 1038363 nuoG Escherichia coli CFT073 NADH dehydrogenase subunit G NP_754710.1 2679944 R 199310 CDS NP_754711.1 26248671 1038364 complement(2682723..2684060) 1 NC_004431.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2684060 nuoF 1038364 nuoF Escherichia coli CFT073 NADH dehydrogenase I subunit F NP_754711.1 2682723 R 199310 CDS NP_754712.1 26248672 1038365 complement(2684057..2684557) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2684557 nuoE 1038365 nuoE Escherichia coli CFT073 NADH dehydrogenase subunit E NP_754712.1 2684057 R 199310 CDS NP_754713.1 26248673 1038366 complement(2684560..2686362) 1 NC_004431.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2686362 nuoC 1038366 nuoC Escherichia coli CFT073 bifunctional NADH:ubiquinone oxidoreductase subunit C/D NP_754713.1 2684560 R 199310 CDS NP_754714.1 26248674 1038369 complement(2686456..2687118) 1 NC_004431.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2687118 nuoB 1038369 nuoB Escherichia coli CFT073 NADH dehydrogenase subunit B NP_754714.1 2686456 R 199310 CDS NP_754715.1 26248675 1038370 complement(2687134..2687577) 1 NC_004431.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2687577 nuoA 1038370 nuoA Escherichia coli CFT073 NADH dehydrogenase subunit A NP_754715.1 2687134 R 199310 CDS NP_754716.1 26248676 1038372 complement(2688207..2689145) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2289; Escherichia coli O157:H7 ortholog: z3549; transcriptional regulator lrhA 2689145 lrhA 1038372 lrhA Escherichia coli CFT073 transcriptional regulator lrhA NP_754716.1 2688207 R 199310 CDS NP_754717.1 26248677 1038373 2690065..2691282 1 NC_004431.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2691282 1038373 c2831 Escherichia coli CFT073 aminotransferase NP_754717.1 2690065 D 199310 CDS NP_754718.1 26248678 1038375 2691366..2691965 1 NC_004431.1 Escherichia coli K-12 ortholog: b2291; Escherichia coli O157:H7 ortholog: z3552; hypothetical protein 2691965 yfbR 1038375 yfbR Escherichia coli CFT073 hypothetical protein NP_754718.1 2691366 D 199310 CDS NP_754719.1 26248679 1038376 complement(2692024..2693856) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2292; Escherichia coli O157:H7 ortholog: z3553; hypothetical protein 2693856 yfbS 1038376 yfbS Escherichia coli CFT073 hypothetical protein NP_754719.1 2692024 R 199310 CDS NP_754720.1 26248680 1038377 complement(2693943..2694593) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2293; Escherichia coli O157:H7 ortholog: z3554; phosphatase 2694593 yfbT 1038377 yfbT Escherichia coli CFT073 phosphatase NP_754720.1 2693943 R 199310 CDS NP_754721.2 161486169 1038378 complement(2694604..2695098) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2294; Escherichia coli O157:H7 ortholog: z3555; hypothetical protein 2695098 1038378 c2835 Escherichia coli CFT073 hypothetical protein NP_754721.2 2694604 R 199310 CDS NP_754722.1 26248682 1038379 complement(2695180..2695635) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2295; Escherichia coli O157:H7 ortholog: z3556; hypothetical protein 2695635 yfbV 1038379 yfbV Escherichia coli CFT073 hypothetical protein NP_754722.1 2695180 R 199310 CDS NP_754723.1 26248683 1038380 complement(2695704..2695835) 1 NC_004431.1 hypothetical protein 2695835 1038380 c2837 Escherichia coli CFT073 hypothetical protein NP_754723.1 2695704 R 199310 CDS NP_754724.1 26248684 1038381 2695973..2697175 1 NC_004431.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2697175 ackA 1038381 ackA Escherichia coli CFT073 acetate kinase NP_754724.1 2695973 D 199310 CDS NP_754725.1 26248685 1038382 complement(2697178..2699448) 1 NC_004431.1 hypothetical protein 2699448 1038382 c2839 Escherichia coli CFT073 hypothetical protein NP_754725.1 2697178 R 199310 CDS NP_754726.1 26248686 1038383 2697250..2699394 1 NC_004431.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2699394 pta 1038383 pta Escherichia coli CFT073 phosphate acetyltransferase NP_754726.1 2697250 D 199310 CDS NP_754727.2 161486168 1038386 2699584..2701104 1 NC_004431.1 Escherichia coli K-12 ortholog: b2298; Escherichia coli O157:H7 ortholog: z3560; hypothetical protein 2701104 yfcC 1038386 yfcC Escherichia coli CFT073 hypothetical protein NP_754727.2 2699584 D 199310 CDS NP_754728.1 26248688 1038387 complement(2701137..2701679) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2299; Escherichia coli O157:H7 ortholog: z3561; hypothetical protein 2701679 yfcD 1038387 yfcD Escherichia coli CFT073 hypothetical protein NP_754728.1 2701137 R 199310 CDS NP_754729.1 26248689 1038388 complement(2701737..2702291) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2300; Escherichia coli O157:H7 ortholog: z3562; phosphodiesterase 2702291 yfcE 1038388 yfcE Escherichia coli CFT073 phosphodiesterase NP_754729.1 2701737 R 199310 CDS NP_754730.1 26248690 1038389 complement(2702344..2702988) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2301; Escherichia coli O157:H7 ortholog: z3563; GST-like protein yfcF 2702988 yfcF 1038389 yfcF Escherichia coli CFT073 GST-like protein yfcF NP_754730.1 2702344 R 199310 CDS NP_754731.1 26248691 1038392 2703124..2703771 1 NC_004431.1 Escherichia coli K-12 ortholog: b2302; Escherichia coli O157:H7 ortholog: z3564; glutathione S-transferase 2703771 yfcG 1038392 yfcG Escherichia coli CFT073 glutathione S-transferase NP_754731.1 2703124 D 199310 CDS NP_754732.1 26248692 1038393 2703828..2704190 1 NC_004431.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2704190 folX 1038393 folX Escherichia coli CFT073 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase NP_754732.1 2703828 D 199310 CDS NP_754733.1 26248693 1038395 2704211..2705104 1 NC_004431.1 Escherichia coli K-12 ortholog: b2304; Escherichia coli O157:H7 ortholog: z3566; hypothetical protein 2705104 yfcH 1038395 yfcH Escherichia coli CFT073 hypothetical protein NP_754733.1 2704211 D 199310 CDS NP_754734.1 26248694 1038397 complement(2705263..2706036) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2306; Escherichia coli O157:H7 ortholog: z3568; histidine/lysine/arginine/ornithine transporter subunit 2706036 hisP 1038397 hisP Escherichia coli CFT073 histidine/lysine/arginine/ornithine transporter subunit NP_754734.1 2705263 R 199310 CDS NP_754735.1 26248695 1038399 complement(2706044..2706760) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2307; Escherichia coli O157:H7 ortholog: z3569; histidine transport system permease hisM 2706760 hisM 1038399 hisM Escherichia coli CFT073 histidine transport system permease hisM NP_754735.1 2706044 R 199310 CDS NP_754736.1 26248696 1038400 complement(2706757..2707443) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2308; Escherichia coli O157:H7 ortholog: z3570; histidine transport system permease hisQ 2707443 hisQ 1038400 hisQ Escherichia coli CFT073 histidine transport system permease hisQ NP_754736.1 2706757 R 199310 CDS NP_754737.1 26248697 1038401 complement(2707533..2708315) 1 NC_004431.1 HBP; Escherichia coli K-12 ortholog: b2309; Escherichia coli O157:H7 ortholog: z3571; histidine-binding periplasmic protein 2708315 hisJ 1038401 hisJ Escherichia coli CFT073 histidine-binding periplasmic protein NP_754737.1 2707533 R 199310 CDS NP_754738.1 26248698 1038405 complement(2709463..2709606) 1 NC_004431.1 hypothetical protein 2709606 1038405 c2854 Escherichia coli CFT073 hypothetical protein NP_754738.1 2709463 R 199310 CDS NP_754739.1 26248699 1038407 complement(2709584..2710153) 1 NC_004431.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2710153 ubiX 1038407 ubiX Escherichia coli CFT073 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_754739.1 2709584 R 199310 CDS NP_754740.1 26248700 1038408 complement(2710248..2711765) 1 NC_004431.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2711765 purF 1038408 purF Escherichia coli CFT073 amidophosphoribosyltransferase NP_754740.1 2710248 R 199310 CDS NP_754741.1 26248701 1038409 complement(2711802..2712290) 1 NC_004431.1 membrane protein required for colicin V production; colicin V production protein 2712290 cvpA 1038409 cvpA Escherichia coli CFT073 colicin V production protein NP_754741.1 2711802 R 199310 CDS NP_754742.1 26248702 1038412 2712392..2712562 1 NC_004431.1 Escherichia coli K-12 ortholog: b0100; hypothetical protein 2712562 1038412 c2858 Escherichia coli CFT073 hypothetical protein NP_754742.1 2712392 D 199310 CDS NP_754743.2 161486167 1038414 complement(2712822..2713484) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2314; Escherichia coli O157:H7 ortholog: z3576; hypothetical protein 2713484 dedD 1038414 dedD Escherichia coli CFT073 hypothetical protein NP_754743.2 2712822 R 199310 CDS NP_754744.1 26248704 1038415 complement(2713474..2714742) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2315; Escherichia coli O157:H7 ortholog: z3577; bifunctional; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2714742 folC 1038415 folC Escherichia coli CFT073 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase NP_754744.1 2713474 R 199310 CDS NP_754745.2 161486166 1038416 complement(2714812..2715726) 1 NC_004431.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2715726 accD 1038416 accD Escherichia coli CFT073 acetyl-CoA carboxylase subunit beta NP_754745.2 2714812 R 199310 CDS NP_754746.1 26248706 1038417 complement(2715882..2716541) 1 NC_004431.1 DSG-1 protein; Escherichia coli K-12 ortholog: b2317; Escherichia coli O157:H7 ortholog: z3579; hypothetical protein 2716541 dedA 1038417 dedA Escherichia coli CFT073 hypothetical protein NP_754746.1 2715882 R 199310 CDS NP_754747.1 26248707 1038418 complement(2716624..2717436) 1 NC_004431.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2717436 truA 1038418 truA Escherichia coli CFT073 tRNA pseudouridine synthase A NP_754747.1 2716624 R 199310 CDS NP_754748.1 26248708 1038419 complement(2717436..2718449) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2319; Escherichia coli O157:H7 ortholog: z3581; semialdehyde dehydrogenase 2718449 usg 1038419 usg Escherichia coli CFT073 semialdehyde dehydrogenase NP_754748.1 2717436 R 199310 CDS NP_754749.1 26248709 1038420 complement(2718515..2719651) 1 NC_004431.1 catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate; erythronate-4-phosphate dehydrogenase 2719651 pdxB 1038420 pdxB Escherichia coli CFT073 erythronate-4-phosphate dehydrogenase NP_754749.1 2718515 R 199310 CDS NP_754750.1 26248710 1038421 2719750..2720745 1 NC_004431.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2720745 flk 1038421 flk Escherichia coli CFT073 flagella biosynthesis regulator NP_754750.1 2719750 D 199310 CDS NP_754751.1 26248711 1038429 complement(2722183..2723403) 1 NC_004431.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2723403 fabB 1038429 fabB Escherichia coli CFT073 3-oxoacyl-ACP synthase NP_754751.1 2722183 R 199310 CDS NP_754752.2 161486165 1038430 2723562..2725568 1 NC_004431.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2725568 mnmC 1038430 mnmC Escherichia coli CFT073 5-methylaminomethyl-2-thiouridine methyltransferase NP_754752.2 2723562 D 199310 CDS NP_754753.1 26248713 1038431 complement(2725689..2725967) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2325; Escherichia coli O157:H7 ortholog: z3588; hypothetical protein 2725967 yfcL 1038431 yfcL Escherichia coli CFT073 hypothetical protein NP_754753.1 2725689 R 199310 CDS NP_754754.1 26248714 1038433 complement(2726001..2726549) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2326; Escherichia coli O157:H7 ortholog: z3589; hypothetical protein 2726549 yfcM 1038433 yfcM Escherichia coli CFT073 hypothetical protein NP_754754.1 2726001 R 199310 CDS NP_754755.1 26248715 1038435 complement(2726549..2727358) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2327; Escherichia coli O157:H7 ortholog: z3590; hypothetical protein 2727358 yfcA 1038435 yfcA Escherichia coli CFT073 hypothetical protein NP_754755.1 2726549 R 199310 CDS NP_754756.1 26248716 1038436 complement(2727358..2728182) 1 NC_004431.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2728182 mepA 1038436 mepA Escherichia coli CFT073 penicillin-insensitive murein endopeptidase NP_754756.1 2727358 R 199310 CDS NP_754757.1 26248717 1038437 complement(2728186..2729274) 1 NC_004431.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2729274 aroC 1038437 aroC Escherichia coli CFT073 chorismate synthase NP_754757.1 2728186 R 199310 CDS NP_754758.1 26248718 1038438 complement(2729306..2730571) 1 NC_004431.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2730571 yfcB 1038438 yfcB Escherichia coli CFT073 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase NP_754758.1 2729306 R 199310 CDS NP_754759.1 26248719 1038439 2730404..2730955 1 NC_004431.1 Escherichia coli K-12 ortholog: b2331; Escherichia coli O157:H7 ortholog: z3594; hypothetical protein 2730955 yfcN 1038439 yfcN Escherichia coli CFT073 hypothetical protein NP_754759.1 2730404 D 199310 CDS NP_754760.1 26248720 1038440 complement(2731275..2732147) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2332; Escherichia coli O157:H7 ortholog: z3595; hypothetical protein 2732147 yfcO 1038440 yfcO Escherichia coli CFT073 hypothetical protein NP_754760.1 2731275 R 199310 CDS NP_754761.1 26248721 1038441 complement(2732134..2732661) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2333; Escherichia coli O157:H7 ortholog: z3596; fimbrial-like protein yfcP 2732661 yfcP 1038441 yfcP Escherichia coli CFT073 fimbrial-like protein yfcP NP_754761.1 2732134 R 199310 CDS NP_754762.1 26248722 1038442 complement(2732658..2733137) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2334; Escherichia coli O157:H7 ortholog: z3597; fimbrial-like protein yfcQ 2733137 yfcQ 1038442 yfcQ Escherichia coli CFT073 fimbrial-like protein yfcQ NP_754762.1 2732658 R 199310 CDS NP_754763.1 26248723 1038443 complement(2733134..2733637) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2335; Escherichia coli O157:H7 ortholog: z3598; hypothetical protein 2733637 yfcR 1038443 yfcR Escherichia coli CFT073 hypothetical protein NP_754763.1 2733134 R 199310 CDS NP_754764.1 26248724 1038445 complement(2733654..2734406) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2336; Escherichia coli O157:H7 ortholog: z3599; fimbrial chaperone yfcS 2734406 yfcS 1038445 yfcS Escherichia coli CFT073 fimbrial chaperone yfcS NP_754764.1 2733654 R 199310 CDS NP_754765.1 26248725 1038446 complement(2734426..2737080) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2338; Escherichia coli O157:H7 ortholog: z3600; hypothetical protein 2737080 yfcU 1038446 yfcU Escherichia coli CFT073 hypothetical protein NP_754765.1 2734426 R 199310 CDS NP_754766.1 26248726 1038447 complement(2737155..2737721) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2339; Escherichia coli O157:H7 ortholog: z3601; fimbrial-like protein yfcV 2737721 yfcV 1038447 yfcV Escherichia coli CFT073 fimbrial-like protein yfcV NP_754766.1 2737155 R 199310 CDS NP_754767.1 26248727 1038448 complement(2738288..2738773) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2340; Escherichia coli O157:H7 ortholog: z3603; phosphohistidine phosphatase 2738773 1038448 c2885 Escherichia coli CFT073 phosphohistidine phosphatase NP_754767.1 2738288 R 199310 CDS NP_754768.1 26248728 1038451 complement(2738976..2741120) 1 NC_004431.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2741120 fadJ 1038451 fadJ Escherichia coli CFT073 multifunctional fatty acid oxidation complex subunit alpha NP_754768.1 2738976 R 199310 CDS NP_754769.1 26248729 1038455 complement(2741120..2742430) 1 NC_004431.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2742430 fadI 1038455 fadI Escherichia coli CFT073 3-ketoacyl-CoA thiolase NP_754769.1 2741120 R 199310 CDS NP_754770.1 26248730 1038456 complement(2742610..2742918) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2343; Escherichia coli O157:H7 ortholog: z3606; hypothetical protein 2742918 yfcZ 1038456 yfcZ Escherichia coli CFT073 hypothetical protein NP_754770.1 2742610 R 199310 CDS NP_754771.1 26248731 1038457 2743260..2744606 1 NC_004431.1 Outer membrane FADL protein; Escherichia coli K-12 ortholog: b2344; Escherichia coli O157:H7 ortholog: z3608; long-chain fatty acid outer membrane transporter 2744606 fadL 1038457 fadL Escherichia coli CFT073 long-chain fatty acid outer membrane transporter NP_754771.1 2743260 D 199310 CDS NP_754772.1 26248732 1038459 complement(2744668..2745423) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2346; Escherichia coli O157:H7 ortholog: z3610; VacJ lipoprotein 2745423 vacJ 1038459 vacJ Escherichia coli CFT073 VacJ lipoprotein NP_754772.1 2744668 R 199310 CDS NP_754773.1 26248733 1038461 complement(2745449..2745619) 1 NC_004431.1 hypothetical protein 2745619 1038461 c2891 Escherichia coli CFT073 hypothetical protein NP_754773.1 2745449 R 199310 CDS NP_754774.1 26248734 1038462 2745717..2746649 1 NC_004431.1 Escherichia coli K-12 ortholog: b2347; Escherichia coli O157:H7 ortholog: z3611; hypothetical protein 2746649 yfdC 1038462 yfdC Escherichia coli CFT073 hypothetical protein NP_754774.1 2745717 D 199310 CDS NP_754775.1 26248735 1038464 complement(2747237..2747767) 1 NC_004431.1 hypothetical protein 2747767 1038464 c2893 Escherichia coli CFT073 hypothetical protein NP_754775.1 2747237 R 199310 CDS NP_754776.1 26248736 1038466 complement(2747815..2748690) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1509; hypothetical protein 2748690 ydeU 1038466 ydeU Escherichia coli CFT073 hypothetical protein NP_754776.1 2747815 R 199310 CDS NP_754777.1 26248737 1038467 complement(2748603..2755766) 1 NC_004431.1 Residues 45 to 1255 of 2387 are 21.57 pct identical to residues 2499 to 3684 of 3705 from GenPept.129 : >emb|CAC89847.1| (AJ414146) autotransporter protein [Yersinia pestis]; yapH-like protein 2755766 1038467 c2895 Escherichia coli CFT073 yapH-like protein NP_754777.1 2748603 R 199310 CDS NP_754778.1 26248738 1038470 complement(2755791..2756411) 1 NC_004431.1 hypothetical protein 2756411 1038470 c2896 Escherichia coli CFT073 hypothetical protein NP_754778.1 2755791 R 199310 CDS NP_754779.1 26248739 1038471 complement(2756729..2757358) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4312; Escherichia coli O157:H7 ortholog: z5910; Type 1 fimbriae regulatory protein fimB 2757358 1038471 c2897 Escherichia coli CFT073 Type 1 fimbriae regulatory protein fimB NP_754779.1 2756729 R 199310 CDS NP_754780.1 26248740 1038472 2758106..2758675 1 NC_004431.1 Escherichia coli K-12 ortholog: b4312; Escherichia coli O157:H7 ortholog: z5910; Type 1 fimbriae regulatory protein fimB 2758675 1038472 c2898 Escherichia coli CFT073 Type 1 fimbriae regulatory protein fimB NP_754780.1 2758106 D 199310 CDS NP_754781.1 26248741 1038477 complement(2759070..2760023) 1 NC_004431.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 2760023 dsdC 1038477 dsdC Escherichia coli CFT073 DNA-binding transcriptional regulator DsdC NP_754781.1 2759070 R 199310 CDS NP_754782.1 26248742 1038478 2760235..2761572 1 NC_004431.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2761572 dsdX 1038478 dsdX Escherichia coli CFT073 permease DsdX NP_754782.1 2760235 D 199310 CDS NP_754783.1 26248743 1038480 2761590..2762918 1 NC_004431.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2762918 dsdA 1038480 dsdA Escherichia coli CFT073 D-serine dehydratase NP_754783.1 2761590 D 199310 CDS NP_754784.1 26248744 1038481 complement(2763026..2764564) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2367; Escherichia coli O157:H7 ortholog: z3629; multidrug resistance protein Y 2764564 emrY 1038481 emrY Escherichia coli CFT073 multidrug resistance protein Y NP_754784.1 2763026 R 199310 CDS NP_754785.1 26248745 1038483 2764251..2764589 1 NC_004431.1 hypothetical protein 2764589 1038483 c2903 Escherichia coli CFT073 hypothetical protein NP_754785.1 2764251 D 199310 CDS NP_754786.1 26248746 1038484 complement(2764564..2765727) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2368; Escherichia coli O157:H7 ortholog: z3630; multidrug resistance protein K 2765727 emrK 1038484 emrK Escherichia coli CFT073 multidrug resistance protein K NP_754786.1 2764564 R 199310 CDS NP_754787.1 26248747 1038485 2766143..2766757 1 NC_004431.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2766757 evgA 1038485 evgA Escherichia coli CFT073 DNA-binding transcriptional activator EvgA NP_754787.1 2766143 D 199310 CDS NP_754788.1 26248748 1038486 2766762..2770355 1 NC_004431.1 Escherichia coli K-12 ortholog: b2370; Escherichia coli O157:H7 ortholog: z3632; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2770355 evgS 1038486 evgS Escherichia coli CFT073 hybrid sensory histidine kinase in two-component regulatory system with EvgA NP_754788.1 2766762 D 199310 CDS NP_754789.1 26248749 1038487 complement(2770411..2771595) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2371; Escherichia coli O157:H7 ortholog: z3633; hypothetical protein 2771595 yfdE 1038487 yfdE Escherichia coli CFT073 hypothetical protein NP_754789.1 2770411 R 199310 CDS NP_754790.1 26248750 1038492 complement(2771630..2772574) 1 NC_004431.1 member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV 2772574 yfdV 1038492 yfdV Escherichia coli CFT073 transporter YfdV NP_754790.1 2771630 R 199310 CDS NP_754791.1 26248751 1038493 complement(2772644..2774338) 1 NC_004431.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase 2774338 1038493 c2909 Escherichia coli CFT073 oxalyl-CoA decarboxylase NP_754791.1 2772644 R 199310 CDS NP_754792.1 26248752 1038494 complement(2774392..2775642) 1 NC_004431.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2775642 yfdW 1038494 yfdW Escherichia coli CFT073 formyl-coenzyme A transferase NP_754792.1 2774392 R 199310 CDS NP_754793.1 26248753 1038495 complement(2776154..2776786) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2375; Escherichia coli O157:H7 ortholog: z3640; hypothetical protein 2776786 1038495 c2911 Escherichia coli CFT073 hypothetical protein NP_754793.1 2776154 R 199310 CDS NP_754794.1 26248754 1038499 2777081..2777356 1 NC_004431.1 Escherichia coli K-12 ortholog: b2376; Escherichia coli O157:H7 ortholog: z3641; lipoprotein ypdI 2777356 ypdI 1038499 ypdI Escherichia coli CFT073 lipoprotein ypdI NP_754794.1 2777081 D 199310 CDS NP_754795.1 26248755 1038500 complement(2777341..2777478) 1 NC_004431.1 hypothetical protein 2777478 1038500 c2913 Escherichia coli CFT073 hypothetical protein NP_754795.1 2777341 R 199310 CDS NP_754796.1 26248756 1038503 complement(2777433..2777675) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2377; Escherichia coli O157:H7 ortholog: z3642; hypothetical protein 2777675 yfdY 1038503 yfdY Escherichia coli CFT073 hypothetical protein NP_754796.1 2777433 R 199310 CDS NP_754797.2 161486164 1038504 2778028..2778948 1 NC_004431.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2778948 ddg 1038504 ddg Escherichia coli CFT073 lipid A biosynthesis palmitoleoyl acyltransferase NP_754797.2 2778028 D 199310 CDS NP_754798.1 26248758 1038505 complement(2779440..2780678) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2379; Escherichia coli O157:H7 ortholog: z3644; aminotransferase 2780678 yfdZ 1038505 yfdZ Escherichia coli CFT073 aminotransferase NP_754798.1 2779440 R 199310 CDS NP_754799.1 26248759 1038508 complement(2780597..2780728) 1 NC_004431.1 hypothetical protein 2780728 1038508 c2917 Escherichia coli CFT073 hypothetical protein NP_754799.1 2780597 R 199310 CDS NP_754800.1 26248760 1038511 complement(2780865..2781002) 1 NC_004431.1 hypothetical protein 2781002 1038511 c2918 Escherichia coli CFT073 hypothetical protein NP_754800.1 2780865 R 199310 CDS NP_754801.1 26248761 1038513 2781054..2782751 1 NC_004431.1 Escherichia coli K-12 ortholog: b2380; Escherichia coli O157:H7 ortholog: z3645; hypothetical protein 2782751 ypdA 1038513 ypdA Escherichia coli CFT073 hypothetical protein NP_754801.1 2781054 D 199310 CDS NP_754802.1 26248762 1038514 2782748..2783503 1 NC_004431.1 Escherichia coli K-12 ortholog: b2381; Escherichia coli O157:H7 ortholog: z3646; hypothetical protein 2783503 ypdB 1038514 ypdB Escherichia coli CFT073 hypothetical protein NP_754802.1 2782748 D 199310 CDS NP_754803.1 26248763 1038515 2783516..2784373 1 NC_004431.1 Escherichia coli K-12 ortholog: b2382; Escherichia coli O157:H7 ortholog: z3647; transcriptional regulator YpdC 2784373 ypdC 1038515 ypdC Escherichia coli CFT073 transcriptional regulator YpdC NP_754803.1 2783516 D 199310 CDS NP_754804.1 26248764 1038516 complement(2784376..2786871) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2383; Escherichia coli O157:H7 ortholog: z3648; phosphoenolpyruvate-protein phosphotransferase ypdD 2786871 1038516 c2922 Escherichia coli CFT073 phosphoenolpyruvate-protein phosphotransferase ypdD NP_754804.1 2784376 R 199310 CDS NP_754805.1 26248765 1038519 complement(2786896..2787933) 1 NC_004431.1 metalloprotein; exoaminopeptidase 2787933 ypdE 1038519 ypdE Escherichia coli CFT073 exoaminopeptidase NP_754805.1 2786896 R 199310 CDS NP_754806.1 26248766 1038523 complement(2787933..2789018) 1 NC_004431.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2789018 1038523 c2924 Escherichia coli CFT073 aminopeptidase NP_754806.1 2787933 R 199310 CDS NP_754807.1 26248767 1038524 complement(2789034..2790281) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2386; Escherichia coli O157:H7 ortholog: z3652; PTS system IIC component ypdG 2790281 1038524 c2925 Escherichia coli CFT073 PTS system IIC component ypdG NP_754807.1 2789034 R 199310 CDS NP_754808.1 26248768 1038525 complement(2790303..2790680) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2387; Escherichia coli O157:H7 ortholog: z3653; PTS system IIB component ypdH 2790680 1038525 c2926 Escherichia coli CFT073 PTS system IIB component ypdH NP_754808.1 2790303 R 199310 CDS NP_754809.1 26248769 1038526 complement(2790848..2791813) 1 NC_004431.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2791813 glk 1038526 glk Escherichia coli CFT073 glucokinase NP_754809.1 2790848 R 199310 CDS NP_754810.1 26248770 1038527 2792017..2793273 1 NC_004431.1 Escherichia coli K-12 ortholog: b2389; Escherichia coli O157:H7 ortholog: z3655; hypothetical protein 2793273 yfeO 1038527 yfeO Escherichia coli CFT073 hypothetical protein NP_754810.1 2792017 D 199310 CDS NP_754811.1 26248771 1038529 2793388..2793714 1 NC_004431.1 Escherichia coli K-12 ortholog: b2390; Escherichia coli O157:H7 ortholog: z3656; hypothetical protein 2793714 ypeC 1038529 ypeC Escherichia coli CFT073 hypothetical protein NP_754811.1 2793388 D 199310 CDS YP_004853816.1 347357935 1038530 2793437..2793796 1 NC_004431.1 hypothetical protein 2793796 1038530 c2930 Escherichia coli CFT073 hypothetical protein YP_004853816.1 2793437 D 199310 CDS NP_754813.1 26248773 1038531 complement(2793855..2795093) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2392; Escherichia coli O157:H7 ortholog: z3658; manganese transport protein MntH 2795093 1038531 c2931 Escherichia coli CFT073 manganese transport protein MntH NP_754813.1 2793855 R 199310 CDS NP_754814.1 26248774 1038532 2795390..2796631 1 NC_004431.1 Nucleoside-transport system protein nupC; Escherichia coli K-12 ortholog: b2393; Escherichia coli O157:H7 ortholog: z3659; nucleoside permease nupC 2796631 nupC 1038532 nupC Escherichia coli CFT073 nucleoside permease nupC NP_754814.1 2795390 D 199310 CDS NP_754815.1 26248775 1038533 complement(2796680..2798929) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2395; Escherichia coli O157:H7 ortholog: z3660; hypothetical protein 2798929 yfeA 1038533 yfeA Escherichia coli CFT073 hypothetical protein NP_754815.1 2796680 R 199310 CDS NP_754816.1 26248776 1038539 2799487..2799846 1 NC_004431.1 Escherichia coli K-12 ortholog: b2398; Escherichia coli O157:H7 ortholog: z3662; hypothetical protein 2799846 yfeC 1038539 yfeC Escherichia coli CFT073 hypothetical protein NP_754816.1 2799487 D 199310 CDS NP_754817.1 26248777 1038540 2799848..2800240 1 NC_004431.1 Escherichia coli K-12 ortholog: b2399; Escherichia coli O157:H7 ortholog: z3663; hypothetical protein 2800240 yfeD 1038540 yfeD Escherichia coli CFT073 hypothetical protein NP_754817.1 2799848 D 199310 CDS NP_754818.1 26248778 1038541 complement(2800291..2801706) 1 NC_004431.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2801706 gltX 1038541 gltX Escherichia coli CFT073 glutamyl-tRNA synthetase NP_754818.1 2800291 R 199310 CDS NP_754819.1 26248779 1038559 complement(2802472..2803371) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2405; DNA-binding transcriptional activator XapR 2803371 xapR 1038559 xapR Escherichia coli CFT073 DNA-binding transcriptional activator XapR NP_754819.1 2802472 R 199310 CDS NP_754820.1 26248780 1038561 complement(2803397..2803555) 1 NC_004431.1 Residues 1 to 52 of 52 are 40.38 pct identical to residues 1 to 52 of 53 from GenPept.129 : >dbj|BAB07525.1| (AP001520) BH3806; unknown [Bacillus halodurans]; hypothetical protein 2803555 1038561 c2938 Escherichia coli CFT073 hypothetical protein NP_754820.1 2803397 R 199310 CDS NP_754821.1 26248781 1038563 complement(2803608..2804864) 1 NC_004431.1 Xanthosine transporter; Escherichia coli K-12 ortholog: b2406; Escherichia coli O157:H7 ortholog: z4309; xanthosine permease 2804864 xapB 1038563 xapB Escherichia coli CFT073 xanthosine permease NP_754821.1 2803608 R 199310 CDS NP_754822.1 26248782 1038564 complement(2804925..2805758) 1 NC_004431.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 2805758 xapA 1038564 xapA Escherichia coli CFT073 purine nucleoside phosphorylase NP_754822.1 2804925 R 199310 CDS NP_754823.2 161486163 1038565 2806006..2806770 1 NC_004431.1 Escherichia coli K-12 ortholog: b2408; hypothetical protein 2806770 yfeN 1038565 yfeN Escherichia coli CFT073 hypothetical protein NP_754823.2 2806006 D 199310 CDS NP_754824.1 26248784 1038566 complement(2806809..2807735) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2409; transcriptional regulator YfeR 2807735 yfeR 1038566 yfeR Escherichia coli CFT073 transcriptional regulator YfeR NP_754824.1 2806809 R 199310 CDS NP_754825.1 26248785 1038570 2807825..2808823 1 NC_004431.1 Escherichia coli K-12 ortholog: b2410; Escherichia coli O157:H7 ortholog: z3675; hypothetical protein 2808823 yfeH 1038570 yfeH Escherichia coli CFT073 hypothetical protein NP_754825.1 2807825 D 199310 CDS NP_754826.1 26248786 1038575 complement(2808820..2809038) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3676; hypothetical protein 2809038 1038575 c2944 Escherichia coli CFT073 hypothetical protein NP_754826.1 2808820 R 199310 CDS NP_754827.1 26248787 1038577 complement(2809040..2811055) 1 NC_004431.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2811055 ligA 1038577 ligA Escherichia coli CFT073 NAD-dependent DNA ligase LigA NP_754827.1 2809040 R 199310 CDS NP_754828.1 26248788 1038578 complement(2811126..2812175) 1 NC_004431.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2812175 zipA 1038578 zipA Escherichia coli CFT073 cell division protein ZipA NP_754828.1 2811126 R 199310 CDS NP_754829.1 26248789 1038579 2812354..2813115 1 NC_004431.1 role in sulfur assimilation; sulfate transport protein CysZ 2813115 cysZ 1038579 cysZ Escherichia coli CFT073 sulfate transport protein CysZ NP_754829.1 2812354 D 199310 CDS NP_754830.1 26248790 1038580 2813300..2814283 1 NC_004431.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2814283 cysK 1038580 cysK Escherichia coli CFT073 cysteine synthase A NP_754830.1 2813300 D 199310 CDS NP_754831.1 26248791 1038582 complement(2814394..2814519) 1 NC_004431.1 hypothetical protein 2814519 1038582 c2949 Escherichia coli CFT073 hypothetical protein NP_754831.1 2814394 R 199310 CDS NP_754832.1 26248792 1038584 2814656..2814913 1 NC_004431.1 Histidine-containing protein; Escherichia coli K-12 ortholog: b2415; Escherichia coli O157:H7 ortholog: z3681; PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2814913 ptsH 1038584 ptsH Escherichia coli CFT073 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr NP_754832.1 2814656 D 199310 CDS NP_754833.1 26248793 1038585 2815190..2816686 1 NC_004431.1 Escherichia coli K-12 ortholog: b2416; Escherichia coli O157:H7 ortholog: z3682; phosphoenolpyruvate-protein phosphotransferase 2816686 ptsI 1038585 ptsI Escherichia coli CFT073 phosphoenolpyruvate-protein phosphotransferase NP_754833.1 2815190 D 199310 CDS NP_754834.1 26248794 1038586 2816727..2817236 1 NC_004431.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2817236 crr 1038586 crr Escherichia coli CFT073 PTS system glucose-specific transporter subunit NP_754834.1 2816727 D 199310 CDS NP_754835.1 26248795 1038587 complement(2817279..2818130) 1 NC_004431.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2818130 pdxK 1038587 pdxK Escherichia coli CFT073 pyridoxal kinase NP_754835.1 2817279 R 199310 CDS NP_754836.1 26248796 1038588 2818235..2818603 1 NC_004431.1 Escherichia coli K-12 ortholog: b2419; Escherichia coli O157:H7 ortholog: z3685; hypothetical protein 2818603 yfeK 1038588 yfeK Escherichia coli CFT073 hypothetical protein NP_754836.1 2818235 D 199310 CDS NP_754837.1 26248797 1038591 complement(2818606..2819517) 1 NC_004431.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2819517 cysM 1038591 cysM Escherichia coli CFT073 cysteine synthase B NP_754837.1 2818606 R 199310 CDS NP_754838.1 26248798 1038592 complement(2819652..2820749) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2422; Escherichia coli O157:H7 ortholog: z3687; sulfate/thiosulfate transporter subunit 2820749 cysA 1038592 cysA Escherichia coli CFT073 sulfate/thiosulfate transporter subunit NP_754838.1 2819652 R 199310 CDS NP_754839.1 26248799 1038593 complement(2820739..2821614) 1 NC_004431.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 2821614 cysW 1038593 cysW Escherichia coli CFT073 sulfate/thiosulfate transporter permease subunit NP_754839.1 2820739 R 199310 CDS NP_754840.1 26248800 1038594 complement(2821614..2822447) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2424; Escherichia coli O157:H7 ortholog: z3689; sulfate/thiosulfate transporter subunit 2822447 cysU 1038594 cysU Escherichia coli CFT073 sulfate/thiosulfate transporter subunit NP_754840.1 2821614 R 199310 CDS NP_754841.1 26248801 1038596 complement(2822447..2823463) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2425; Escherichia coli O157:H7 ortholog: z3690; thiosulfate transporter subunit 2823463 cysP 1038596 cysP Escherichia coli CFT073 thiosulfate transporter subunit NP_754841.1 2822447 R 199310 CDS NP_754842.2 161486162 1038597 complement(2823621..2824412) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2426; Escherichia coli O157:H7 ortholog: z3691; short chain dehydrogenase 2824412 ucpA 1038597 ucpA Escherichia coli CFT073 short chain dehydrogenase NP_754842.2 2823621 R 199310 CDS NP_754843.1 26248803 1038598 2824692..2825588 1 NC_004431.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2825588 murQ 1038598 murQ Escherichia coli CFT073 N-acetylmuramic acid-6-phosphate etherase NP_754843.1 2824692 D 199310 CDS NP_754844.1 26248804 1038599 2825592..2827016 1 NC_004431.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2827016 murP 1038599 murP Escherichia coli CFT073 PTS system N-acetylmuramic acid transporter subunits EIIBC NP_754844.1 2825592 D 199310 CDS NP_754845.1 26248805 1038601 complement(2827036..2827179) 1 NC_004431.1 hypothetical protein 2827179 1038601 c2963 Escherichia coli CFT073 hypothetical protein NP_754845.1 2827036 R 199310 CDS NP_754846.1 26248806 1038603 2827179..2828105 1 NC_004431.1 hypothetical protein 2828105 1038603 c2964 Escherichia coli CFT073 hypothetical protein NP_754846.1 2827179 D 199310 CDS NP_754847.1 26248807 1038605 complement(2827194..2828120) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2431; Escherichia coli O157:H7 ortholog: z3696; hypothetical protein 2828120 yfeX 1038605 yfeX Escherichia coli CFT073 hypothetical protein NP_754847.1 2827194 R 199310 CDS NP_754848.1 26248808 1038607 complement(2828189..2828764) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2432; Escherichia coli O157:H7 ortholog: z3697; hypothetical protein 2828764 yfeY 1038607 yfeY Escherichia coli CFT073 hypothetical protein NP_754848.1 2828189 R 199310 CDS NP_754849.1 26248809 1038608 complement(2828825..2829280) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2433; Escherichia coli O157:H7 ortholog: z3698; hypothetical protein 2829280 yfeZ 1038608 yfeZ Escherichia coli CFT073 hypothetical protein NP_754849.1 2828825 R 199310 CDS NP_754850.2 161486161 1038610 complement(2829261..2829686) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2434; Escherichia coli O157:H7 ortholog: z3699; acetyltransferase 2829686 ypeA 1038610 ypeA Escherichia coli CFT073 acetyltransferase NP_754850.2 2829261 R 199310 CDS NP_754851.1 26248811 1038611 2829900..2830769 1 NC_004431.1 Escherichia coli K-12 ortholog: b2435; Escherichia coli O157:H7 ortholog: z3700; N-acetylmuramoyl-L-alanine amidase 2830769 amiA 1038611 amiA Escherichia coli CFT073 N-acetylmuramoyl-L-alanine amidase NP_754851.1 2829900 D 199310 CDS NP_754852.1 26248812 1038612 2830770..2831672 1 NC_004431.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2831672 hemF 1038612 hemF Escherichia coli CFT073 coproporphyrinogen III oxidase NP_754852.1 2830770 D 199310 CDS NP_754853.1 26248813 1038613 complement(2831678..2832730) 1 NC_004431.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2832730 yfeG 1038613 yfeG Escherichia coli CFT073 transcriptional regulator EutR NP_754853.1 2831678 R 199310 CDS NP_754854.1 26248814 1038614 complement(2832776..2833282) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2438; Escherichia coli O157:H7 ortholog: z3703; ethanolamine utilization protein EutK 2833282 1038614 c2972 Escherichia coli CFT073 ethanolamine utilization protein EutK NP_754854.1 2832776 R 199310 CDS NP_754855.1 26248815 1038615 complement(2833289..2833948) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2439; Escherichia coli O157:H7 ortholog: z3704; ethanolamine utilization protein EutL 2833948 1038615 c2973 Escherichia coli CFT073 ethanolamine utilization protein EutL NP_754855.1 2833289 R 199310 CDS NP_754856.1 26248816 1038616 complement(2833958..2834845) 1 NC_004431.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2834845 eutC 1038616 eutC Escherichia coli CFT073 ethanolamine ammonia-lyase small subunit NP_754856.1 2833958 R 199310 CDS NP_754857.1 26248817 1038619 complement(2834866..2836227) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2441; Escherichia coli O157:H7 ortholog: z3706; ethanolamine ammonia-lyase heavy chain 2836227 eutB 1038619 eutB Escherichia coli CFT073 ethanolamine ammonia-lyase heavy chain NP_754857.1 2834866 R 199310 CDS NP_754858.1 26248818 1038620 complement(2836239..2837642) 1 NC_004431.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2837642 eutA 1038620 eutA Escherichia coli CFT073 reactivating factor for ethanolamine ammonia lyase NP_754858.1 2836239 R 199310 CDS NP_754859.1 26248819 1038621 complement(2837639..2838865) 1 NC_004431.1 ethanolamine transporter; Escherichia coli K-12 ortholog: b2452; Escherichia coli O157:H7 ortholog: z3708; ethanolamine utilization protein EutH 2838865 eutH 1038621 eutH Escherichia coli CFT073 ethanolamine utilization protein EutH NP_754859.1 2837639 R 199310 CDS NP_754860.1 26248820 1038622 complement(2839082..2840296) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2453; Escherichia coli O157:H7 ortholog: z3709; ethanolamine utilization protein EutG 2840296 eutG 1038622 eutG Escherichia coli CFT073 ethanolamine utilization protein EutG NP_754860.1 2839082 R 199310 CDS NP_754861.1 26248821 1038624 complement(2840259..2841095) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710; ethanolamine utilization protein EutJ 2841095 eutJ 1038624 eutJ Escherichia coli CFT073 ethanolamine utilization protein EutJ NP_754861.1 2840259 R 199310 CDS NP_754862.1 26248822 1038626 complement(2841106..2842509) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2455; Escherichia coli O157:H7 ortholog: z3711; ethanolamine utilization protein EutE 2842509 eutE 1038626 eutE Escherichia coli CFT073 ethanolamine utilization protein EutE NP_754862.1 2841106 R 199310 CDS NP_754863.1 26248823 1038627 complement(2842521..2842808) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2456; Escherichia coli O157:H7 ortholog: z3712; ethanolamine utilization protein EutN 2842808 cchB 1038627 cchB Escherichia coli CFT073 ethanolamine utilization protein EutN NP_754863.1 2842521 R 199310 CDS NP_754864.2 161486160 1038628 complement(2842915..2843208) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2457; Escherichia coli O157:H7 ortholog: z3713; ethanolamine utilization protein EutM 2843208 cchA 1038628 cchA Escherichia coli CFT073 ethanolamine utilization protein EutM NP_754864.2 2842915 R 199310 CDS NP_754865.1 26248825 1038630 complement(2843247..2844263) 1 NC_004431.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2844263 eutD 1038630 eutD Escherichia coli CFT073 phosphotransacetylase NP_754865.1 2843247 R 199310 CDS NP_754866.1 26248826 1038632 complement(2844260..2845063) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2459; Escherichia coli O157:H7 ortholog: z3715; ethanolamine utilization cobalamin adenosyltransferase 2845063 1038632 c2984 Escherichia coli CFT073 ethanolamine utilization cobalamin adenosyltransferase NP_754866.1 2844260 R 199310 CDS NP_754867.1 26248827 1038633 complement(2845060..2845761) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2460; Escherichia coli O157:H7 ortholog: z3716; ethanolamine utilization protein EutQ 2845761 1038633 c2985 Escherichia coli CFT073 ethanolamine utilization protein EutQ NP_754867.1 2845060 R 199310 CDS NP_754868.1 26248828 1038634 complement(2845736..2846215) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2461; Escherichia coli O157:H7 ortholog: z3717; ethanolamine utilization protein EutP 2846215 1038634 c2986 Escherichia coli CFT073 ethanolamine utilization protein EutP NP_754868.1 2845736 R 199310 CDS NP_754869.1 26248829 1038635 complement(2846228..2846635) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2462; Escherichia coli O157:H7 ortholog: z3718; ethanolamine utilization protein EutS 2846635 1038635 c2987 Escherichia coli CFT073 ethanolamine utilization protein EutS NP_754869.1 2846228 R 199310 CDS NP_754870.1 26248830 1038636 complement(2846856..2849135) 1 NC_004431.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2849135 1038636 c2988 Escherichia coli CFT073 malic enzyme NP_754870.1 2846856 R 199310 CDS NP_754871.1 26248831 1038637 2849424..2850374 1 NC_004431.1 Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase A 2850374 talA 1038637 talA Escherichia coli CFT073 transaldolase A NP_754871.1 2849424 D 199310 CDS NP_754872.2 161486159 1038638 2850394..2852397 1 NC_004431.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2852397 tktB 1038638 tktB Escherichia coli CFT073 transketolase NP_754872.2 2850394 D 199310 CDS NP_754873.1 26248833 1038640 complement(2852500..2853543) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2466; Escherichia coli O157:H7 ortholog: z3722; hypothetical protein 2853543 ypfG 1038640 ypfG Escherichia coli CFT073 hypothetical protein NP_754873.1 2852500 R 199310 CDS NP_754874.1 26248834 1038641 complement(2853437..2853568) 1 NC_004431.1 hypothetical protein 2853568 1038641 c2992 Escherichia coli CFT073 hypothetical protein NP_754874.1 2853437 R 199310 CDS NP_754875.1 26248835 1038643 2853443..2853703 1 NC_004431.1 hypothetical protein 2853703 1038643 c2993 Escherichia coli CFT073 hypothetical protein NP_754875.1 2853443 D 199310 CDS NP_754876.1 26248836 1038644 complement(2853669..2854271) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2467; Escherichia coli O157:H7 ortholog: z3723; hypothetical protein 2854271 yffH 1038644 yffH Escherichia coli CFT073 hypothetical protein NP_754876.1 2853669 R 199310 CDS NP_754877.1 26248837 1038647 complement(2854312..2856291) 1 NC_004431.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 2856291 yffG 1038647 yffG Escherichia coli CFT073 oxidoreductase Fe-S binding subunit NP_754877.1 2854312 R 199310 CDS NP_754878.1 26248838 1038649 2856482..2858197 1 NC_004431.1 Escherichia coli K-12 ortholog: b2469; Escherichia coli O157:H7 ortholog: z3726; nitrate/nitrite sensor protein NarQ 2858197 narQ 1038649 narQ Escherichia coli CFT073 nitrate/nitrite sensor protein NarQ NP_754878.1 2856482 D 199310 CDS NP_754879.1 26248839 1038650 2858361..2861474 1 NC_004431.1 Acriflavine resistance protein D; Escherichia coli K-12 ortholog: b2470; Escherichia coli O157:H7 ortholog: z3727; aminoglycoside/multidrug efflux system 2861474 acrD 1038650 acrD Escherichia coli CFT073 aminoglycoside/multidrug efflux system NP_754879.1 2858361 D 199310 CDS NP_754880.1 26248840 1038652 2862013..2862369 1 NC_004431.1 Escherichia coli K-12 ortholog: b2471; Escherichia coli O157:H7 ortholog: z3729; hypothetical protein 2862369 yffB 1038652 yffB Escherichia coli CFT073 hypothetical protein NP_754880.1 2862013 D 199310 CDS NP_754881.1 26248841 1038653 2862373..2863500 1 NC_004431.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2863500 dapE 1038653 dapE Escherichia coli CFT073 succinyl-diaminopimelate desuccinylase NP_754881.1 2862373 D 199310 CDS NP_754882.1 26248842 1038654 2863528..2863728 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3731; hypothetical protein 2863728 1038654 c3000 Escherichia coli CFT073 hypothetical protein NP_754882.1 2863528 D 199310 CDS NP_754883.2 161486158 1038655 complement(2863809..2864507) 1 NC_004431.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 2864507 ypfH 1038655 ypfH Escherichia coli CFT073 esterase NP_754883.2 2863809 R 199310 CDS NP_754884.1 26248844 1038656 complement(2864581..2866596) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2474; Escherichia coli O157:H7 ortholog: z3733; hypothetical protein 2866596 ypfI 1038656 ypfI Escherichia coli CFT073 hypothetical protein NP_754884.1 2864581 R 199310 CDS NP_754885.1 26248845 1038657 complement(2866611..2867474) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2475; Escherichia coli O157:H7 ortholog: z3734; hypothetical protein 2867474 ypfJ 1038657 ypfJ Escherichia coli CFT073 hypothetical protein NP_754885.1 2866611 R 199310 CDS NP_754886.1 26248846 1038660 complement(2867642..2868364) 1 NC_004431.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2868364 purC 1038660 purC Escherichia coli CFT073 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_754886.1 2867642 R 199310 CDS NP_754887.1 26248847 1038661 complement(2868568..2869605) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2477; Escherichia coli O157:H7 ortholog: z3736; lipoprotein 2869605 nlpB 1038661 nlpB Escherichia coli CFT073 lipoprotein NP_754887.1 2868568 R 199310 CDS NP_754888.1 26248848 1038664 complement(2869619..2870515) 1 NC_004431.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2870515 dapA 1038664 dapA Escherichia coli CFT073 dihydrodipicolinate synthase NP_754888.1 2869619 R 199310 CDS NP_754889.2 161486157 1038665 2870643..2871215 1 NC_004431.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2871215 gcvR 1038665 gcvR Escherichia coli CFT073 glycine cleavage system transcriptional repressor NP_754889.2 2870643 D 199310 CDS NP_754890.1 26248850 1038668 2871215..2871685 1 NC_004431.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2871685 bcp 1038668 bcp Escherichia coli CFT073 thioredoxin-dependent thiol peroxidase NP_754890.1 2871215 D 199310 CDS NP_754891.1 26248851 1038669 complement(2871784..2872845) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2493; Escherichia coli O157:H7 ortholog: z3755; permease PerM 2872845 perM 1038669 perM Escherichia coli CFT073 permease PerM NP_754891.1 2871784 R 199310 CDS NP_754892.1 26248852 1038670 2872876..2873052 1 NC_004431.1 hypothetical protein 2873052 1038670 c3010 Escherichia coli CFT073 hypothetical protein NP_754892.1 2872876 D 199310 CDS NP_754893.1 26248853 1038674 2873058..2874521 1 NC_004431.1 Escherichia coli K-12 ortholog: b2494; Escherichia coli O157:H7 ortholog: z3757; hypothetical protein 2874521 yfgC 1038674 yfgC Escherichia coli CFT073 hypothetical protein NP_754893.1 2873058 D 199310 CDS NP_754894.1 26248854 1038675 2874542..2874901 1 NC_004431.1 Escherichia coli K-12 ortholog: b2495; Escherichia coli O157:H7 ortholog: z3758; hypothetical protein 2874901 1038675 c3012 Escherichia coli CFT073 hypothetical protein NP_754894.1 2874542 D 199310 CDS NP_754895.1 26248855 1038677 complement(2875039..2875785) 1 NC_004431.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2875785 yfgE 1038677 yfgE Escherichia coli CFT073 DNA replication initiation factor NP_754895.1 2875039 R 199310 CDS NP_754896.1 26248856 1038679 complement(2875835..2877166) 1 NC_004431.1 Uracil transporter; Escherichia coli K-12 ortholog: b2497; Escherichia coli O157:H7 ortholog: z3760; uracil transporter 2877166 uraA 1038679 uraA Escherichia coli CFT073 uracil transporter NP_754896.1 2875835 R 199310 CDS NP_754897.2 161486156 1038680 complement(2877210..2877836) 1 NC_004431.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2877836 upp 1038680 upp Escherichia coli CFT073 uracil phosphoribosyltransferase NP_754897.2 2877210 R 199310 CDS NP_754898.1 26248858 1038681 2877798..2878142 1 NC_004431.1 hypothetical protein 2878142 1038681 c3016 Escherichia coli CFT073 hypothetical protein NP_754898.1 2877798 D 199310 CDS NP_754899.1 26248859 1038683 2878161..2879198 1 NC_004431.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2879198 purM 1038683 purM Escherichia coli CFT073 phosphoribosylaminoimidazole synthetase NP_754899.1 2878161 D 199310 CDS NP_754900.1 26248860 1038684 2879198..2879836 1 NC_004431.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2879836 purN 1038684 purN Escherichia coli CFT073 phosphoribosylglycinamide formyltransferase NP_754900.1 2879198 D 199310 CDS NP_754901.1 26248861 1038685 2880002..2882074 1 NC_004431.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2882074 ppk 1038685 ppk Escherichia coli CFT073 polyphosphate kinase NP_754901.1 2880002 D 199310 CDS NP_754902.1 26248862 1038687 2882079..2883620 1 NC_004431.1 Escherichia coli K-12 ortholog: b2502; Escherichia coli O157:H7 ortholog: z3765; exopolyphosphatase 2883620 ppx 1038687 ppx Escherichia coli CFT073 exopolyphosphatase NP_754902.1 2882079 D 199310 CDS NP_754903.1 26248863 1038688 complement(2883659..2885902) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2503; Escherichia coli O157:H7 ortholog: z3766; hypothetical protein 2885902 yfgF 1038688 yfgF Escherichia coli CFT073 hypothetical protein NP_754903.1 2883659 R 199310 CDS NP_754904.1 26248864 1038689 complement(2886084..2886236) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3767; hypothetical protein 2886236 1038689 c3022 Escherichia coli CFT073 hypothetical protein NP_754904.1 2886084 R 199310 CDS NP_754905.1 26248865 1038690 complement(2886119..2886409) 1 NC_004431.1 Residues 2 to 63 of 96 are 69.35 pct identical to residues 1 to 62 of 86 from GenPept.129 : >gb|AAL21399.1| (AE008813) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 2886409 1038690 c3023 Escherichia coli CFT073 hypothetical protein NP_754905.1 2886119 R 199310 CDS NP_754906.1 26248866 1038693 2886756..2887274 1 NC_004431.1 Escherichia coli K-12 ortholog: b2505; Escherichia coli O157:H7 ortholog: z3769; lipoprotein yfgH 2887274 yfgH 1038693 yfgH Escherichia coli CFT073 lipoprotein yfgH NP_754906.1 2886756 D 199310 CDS NP_754907.1 26248867 1038696 2887290..2887829 1 NC_004431.1 Escherichia coli K-12 ortholog: b2506; Escherichia coli O157:H7 ortholog: z3770; hypothetical protein 2887829 yfgI 1038696 yfgI Escherichia coli CFT073 hypothetical protein NP_754907.1 2887290 D 199310 CDS NP_754908.1 26248868 1038697 complement(2887923..2889500) 1 NC_004431.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2889500 guaA 1038697 guaA Escherichia coli CFT073 GMP synthase NP_754908.1 2887923 R 199310 CDS NP_754909.1 26248869 1038699 complement(2889569..2891104) 1 NC_004431.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2891104 guaB 1038699 guaB Escherichia coli CFT073 inosine 5'-monophosphate dehydrogenase NP_754909.1 2889569 R 199310 CDS NP_754910.1 26248870 1038700 2891197..2892573 1 NC_004431.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2892573 xseA 1038700 xseA Escherichia coli CFT073 exodeoxyribonuclease VII large subunit NP_754910.1 2891197 D 199310 CDS NP_754911.1 26248871 1038701 complement(2892642..2900693) 1 NC_004431.1 Residues 9 to 2408 of 2683 are 42.82 pct identical to residues 13 to 2434 of 2435 from GenPept.129 : >gb|AAL21408.1| (AE008813) outer membrane protein [Salmonella typhimurium LT2]; RatA-like protein 2900693 1038701 c3029 Escherichia coli CFT073 RatA-like protein NP_754911.1 2892642 R 199310 CDS NP_754912.1 26248872 1038702 complement(2900814..2901791) 1 NC_004431.1 Residues 1 to 325 of 325 are 46.24 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL21410.1| (AE008814) outer membrane protein [Salmonella typhimurium LT2]; SinI-like protein 2901791 1038702 c3030 Escherichia coli CFT073 SinI-like protein NP_754912.1 2900814 R 199310 CDS NP_754913.1 26248873 1038703 complement(2901846..2904053) 1 NC_004431.1 Residues 11 to 735 of 735 are 72.77 pct identical to residues 1 to 730 of 730 from GenPept.129 : >gb|AAL21411.1| (AE008814) Similar to Escherichia coli intimin and Y. pestis invasin proteins [Salmonella typhimurium LT2]; SinH-like protein 2904053 1038703 c3031 Escherichia coli CFT073 SinH-like protein NP_754913.1 2901846 R 199310 CDS NP_754914.1 26248874 1038707 complement(2904232..2904447) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2510; hypothetical protein 2904447 yfgJ 1038707 yfgJ Escherichia coli CFT073 hypothetical protein NP_754914.1 2904232 R 199310 CDS NP_754915.2 161486155 1038709 complement(2904510..2905982) 1 NC_004431.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2905982 engA 1038709 engA Escherichia coli CFT073 GTP-binding protein EngA NP_754915.2 2904510 R 199310 CDS NP_754916.1 26248876 1038710 complement(2906100..2907278) 1 NC_004431.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2907278 yfgL 1038710 yfgL Escherichia coli CFT073 outer membrane protein assembly complex subunit YfgL NP_754916.1 2906100 R 199310 CDS NP_754917.1 26248877 1038711 complement(2907289..2907909) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2513; Escherichia coli O157:H7 ortholog: z3776; hypothetical protein 2907909 yfgM 1038711 yfgM Escherichia coli CFT073 hypothetical protein NP_754917.1 2907289 R 199310 CDS NP_754918.1 26248878 1038712 complement(2907927..2909201) 1 NC_004431.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2909201 hisS 1038712 hisS Escherichia coli CFT073 histidyl-tRNA synthetase NP_754918.1 2907927 R 199310 CDS NP_754919.1 26248879 1038713 complement(2909312..2910430) 1 NC_004431.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2910430 ispG 1038713 ispG Escherichia coli CFT073 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_754919.1 2909312 R 199310 CDS NP_754920.1 26248880 1038716 complement(2910457..2911464) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2516; Escherichia coli O157:H7 ortholog: z3779; cytoskeletal protein RodZ 2911464 yfgA 1038716 yfgA Escherichia coli CFT073 cytoskeletal protein RodZ NP_754920.1 2910457 R 199310 CDS NP_754921.1 26248881 1038717 complement(2911749..2912903) 1 NC_004431.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2912903 yfgB 1038717 yfgB Escherichia coli CFT073 ribosomal RNA large subunit methyltransferase N NP_754921.1 2911749 R 199310 CDS NP_754922.1 26248882 1038718 2913020..2913547 1 NC_004431.1 hypothetical protein 2913547 1038718 c3040 Escherichia coli CFT073 hypothetical protein NP_754922.1 2913020 D 199310 CDS NP_754923.1 26248883 1038720 complement(2913053..2913484) 1 NC_004431.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2913484 ndk 1038720 ndk Escherichia coli CFT073 nucleoside diphosphate kinase NP_754923.1 2913053 R 199310 CDS NP_754924.1 26248884 1038721 complement(2913633..2915945) 1 NC_004431.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2915945 pbpC 1038721 pbpC Escherichia coli CFT073 penicillin-binding protein 1C NP_754924.1 2913633 R 199310 CDS NP_754925.1 26248885 1038722 complement(2915946..2920907) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2520; Escherichia coli O157:H7 ortholog: z3787; lipoprotein yfhM 2920907 yfhM 1038722 yfhM Escherichia coli CFT073 lipoprotein yfhM NP_754925.1 2915946 R 199310 CDS NP_754926.2 161486154 1038726 2921114..2921959 1 NC_004431.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2921959 sseA 1038726 sseA Escherichia coli CFT073 3-mercaptopyruvate sulfurtransferase NP_754926.2 2921114 D 199310 CDS NP_754927.1 26248887 1038728 2921943..2922095 1 NC_004431.1 hypothetical protein 2922095 1038728 c3045 Escherichia coli CFT073 hypothetical protein NP_754927.1 2921943 D 199310 CDS NP_754928.1 26248888 1038730 2922287..2922424 1 NC_004431.1 hypothetical protein 2922424 1038730 c3046 Escherichia coli CFT073 hypothetical protein NP_754928.1 2922287 D 199310 CDS NP_754929.2 161486153 1038731 complement(2922456..2923232) 1 NC_004431.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2923232 sseB 1038731 sseB Escherichia coli CFT073 enhanced serine sensitivity protein SseB NP_754929.2 2922456 R 199310 CDS NP_754930.1 26248890 1038732 complement(2923375..2924658) 1 NC_004431.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 2924658 pepB 1038732 pepB Escherichia coli CFT073 aminopeptidase NP_754930.1 2923375 R 199310 CDS NP_754931.1 26248891 1038733 complement(2924717..2924917) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2524; Escherichia coli O157:H7 ortholog: z3791; hypothetical protein 2924917 yfhJ 1038733 yfhJ Escherichia coli CFT073 hypothetical protein NP_754931.1 2924717 R 199310 CDS NP_754932.1 26248892 1038734 complement(2924929..2925264) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2525; Escherichia coli O157:H7 ortholog: z3792; (2Fe-2S) ferredoxin 2925264 fdx 1038734 fdx Escherichia coli CFT073 (2Fe-2S) ferredoxin NP_754932.1 2924929 R 199310 CDS NP_754933.2 161486152 1038738 complement(2925266..2927116) 1 NC_004431.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2927116 hscA 1038738 hscA Escherichia coli CFT073 chaperone protein HscA NP_754933.2 2925266 R 199310 CDS NP_754934.1 26248894 1038740 complement(2927133..2927648) 1 NC_004431.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2927648 hscB 1038740 hscB Escherichia coli CFT073 co-chaperone HscB NP_754934.1 2927133 R 199310 CDS NP_754935.2 161486151 1038741 complement(2927744..2928067) 1 NC_004431.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2928067 iscA 1038741 iscA Escherichia coli CFT073 iron-sulfur cluster assembly protein NP_754935.2 2927744 R 199310 CDS NP_754936.1 26248896 1038745 2928003..2928485 1 NC_004431.1 hypothetical protein 2928485 1038745 c3054 Escherichia coli CFT073 hypothetical protein NP_754936.1 2928003 D 199310 CDS NP_754937.1 26248897 1038750 complement(2928084..2928470) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2529; Escherichia coli O157:H7 ortholog: z3796; scaffold protein 2928470 1038750 c3055 Escherichia coli CFT073 scaffold protein NP_754937.1 2928084 R 199310 CDS NP_754938.1 26248898 1038751 complement(2928498..2929736) 1 NC_004431.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2929736 yfhO 1038751 yfhO Escherichia coli CFT073 cysteine desulfurase NP_754938.1 2928498 R 199310 CDS NP_754939.1 26248899 1038755 complement(2929824..2930312) 1 NC_004431.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2930312 yfhP 1038755 yfhP Escherichia coli CFT073 DNA-binding transcriptional regulator IscR NP_754939.1 2929824 R 199310 CDS NP_754940.1 26248900 1038756 complement(2930583..2931323) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2532; Escherichia coli O157:H7 ortholog: z3799; tRNA/rRNA methyltransferase YfhQ 2931323 yfhQ 1038756 yfhQ Escherichia coli CFT073 tRNA/rRNA methyltransferase YfhQ NP_754940.1 2930583 R 199310 CDS NP_754941.1 26248901 1038758 2931442..2932245 1 NC_004431.1 Escherichia coli K-12 ortholog: b2533; inositol monophosphatase 2932245 suhB 1038758 suhB Escherichia coli CFT073 inositol monophosphatase NP_754941.1 2931442 D 199310 CDS NP_754942.1 26248902 1038759 2932363..2933244 1 NC_004431.1 Escherichia coli K-12 ortholog: b2534; Escherichia coli O157:H7 ortholog: z3802; hypothetical protein 2933244 yfhR 1038759 yfhR Escherichia coli CFT073 hypothetical protein NP_754942.1 2932363 D 199310 CDS NP_754943.2 161486150 1038760 2933435..2934715 1 NC_004431.1 Escherichia coli K-12 ortholog: b2535; Escherichia coli O157:H7 ortholog: z3804; stationary phase inducible protein CsiE 2934715 csiE 1038760 csiE Escherichia coli CFT073 stationary phase inducible protein CsiE NP_754943.2 2933435 D 199310 CDS NP_754944.1 26248904 1038761 complement(2934707..2935846) 1 NC_004431.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 2935846 hcaT 1038761 hcaT Escherichia coli CFT073 3-phenylpropionic acid transporter NP_754944.1 2934707 R 199310 CDS NP_754945.1 26248905 1038762 complement(2935880..2936023) 1 NC_004431.1 hypothetical protein 2936023 1038762 c3063 Escherichia coli CFT073 hypothetical protein NP_754945.1 2935880 R 199310 CDS NP_754946.1 26248906 1038763 2936066..2936218 1 NC_004431.1 hypothetical protein 2936218 1038763 c3064 Escherichia coli CFT073 hypothetical protein NP_754946.1 2936066 D 199310 CDS NP_754947.1 26248907 1038764 2936209..2936637 1 NC_004431.1 Escherichia coli K-12 ortholog: b2543; Escherichia coli O157:H7 ortholog: z3815; hypothetical protein 2936637 yphA 1038764 yphA Escherichia coli CFT073 hypothetical protein NP_754947.1 2936209 D 199310 CDS NP_754948.1 26248908 1038765 complement(2936797..2937669) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2544; Escherichia coli O157:H7 ortholog: z3816; hypothetical protein 2937669 yphB 1038765 yphB Escherichia coli CFT073 hypothetical protein NP_754948.1 2936797 R 199310 CDS NP_754949.1 26248909 1038767 complement(2937681..2938775) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2545; Escherichia coli O157:H7 ortholog: z3817; hypothetical protein 2938775 yphC 1038767 yphC Escherichia coli CFT073 hypothetical protein NP_754949.1 2937681 R 199310 CDS NP_754950.1 26248910 1038768 complement(2938808..2939806) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2546; Escherichia coli O157:H7 ortholog: z3819; ABC transporter permease 2939806 yphD 1038768 yphD Escherichia coli CFT073 ABC transporter permease NP_754950.1 2938808 R 199310 CDS NP_754951.1 26248911 1038769 complement(2939831..2941342) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2547; Escherichia coli O157:H7 ortholog: z3821; ABC transporter ATP-binding protein 2941342 yphE 1038769 yphE Escherichia coli CFT073 ABC transporter ATP-binding protein NP_754951.1 2939831 R 199310 CDS NP_754952.1 26248912 1038771 complement(2941365..2942348) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2548; Escherichia coli O157:H7 ortholog: z3823; ABC transporter periplasmic-binding protein 2942348 yphF 1038771 yphF Escherichia coli CFT073 ABC transporter periplasmic-binding protein NP_754952.1 2941365 R 199310 CDS NP_754953.1 26248913 1038773 complement(2942445..2945819) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2549; Escherichia coli O157:H7 ortholog: z3825; hypothetical protein 2945819 yphG 1038773 yphG Escherichia coli CFT073 hypothetical protein NP_754953.1 2942445 R 199310 CDS NP_754954.1 26248914 1038774 2945838..2947037 1 NC_004431.1 Escherichia coli K-12 ortholog: b2550; Escherichia coli O157:H7 ortholog: z3826; hypothetical protein 2947037 yphH 1038774 yphH Escherichia coli CFT073 hypothetical protein NP_754954.1 2945838 D 199310 CDS NP_754955.1 26248915 1038775 complement(2947101..2948360) 1 NC_004431.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2948360 glyA 1038775 glyA Escherichia coli CFT073 serine hydroxymethyltransferase NP_754955.1 2947101 R 199310 CDS NP_754956.1 26248916 1038776 2948684..2949874 1 NC_004431.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2949874 hmpA 1038776 hmpA Escherichia coli CFT073 nitric oxide dioxygenase NP_754956.1 2948684 D 199310 CDS NP_754957.1 26248917 1038777 complement(2949919..2950257) 1 NC_004431.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2950257 glnB 1038777 glnB Escherichia coli CFT073 nitrogen regulatory protein P-II 1 NP_754957.1 2949919 R 199310 CDS NP_754958.1 26248918 1038779 complement(2950318..2951691) 1 NC_004431.1 ORF-2; Escherichia coli K-12 ortholog: b2554; Escherichia coli O157:H7 ortholog: z3830; hypothetical protein 2951691 yfhA 1038779 yfhA Escherichia coli CFT073 hypothetical protein NP_754958.1 2950318 R 199310 CDS NP_754959.1 26248919 1038780 complement(2951642..2952361) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2555; Escherichia coli O157:H7 ortholog: z3831; hypothetical protein 2952361 yfhG 1038780 yfhG Escherichia coli CFT073 hypothetical protein NP_754959.1 2951642 R 199310 CDS NP_754960.1 26248920 1038781 complement(2952520..2954010) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2556; Escherichia coli O157:H7 ortholog: z3833; sensor-like histidine kinase yfhK 2954010 yfhK 1038781 yfhK Escherichia coli CFT073 sensor-like histidine kinase yfhK NP_754960.1 2952520 R 199310 CDS NP_754961.1 26248921 1038782 complement(2954523..2958410) 1 NC_004431.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2958410 purL 1038782 purL Escherichia coli CFT073 phosphoribosylformylglycinamidine synthase NP_754961.1 2954523 R 199310 CDS NP_754962.1 26248922 1038783 2958668..2960224 1 NC_004431.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2960224 yfhD 1038783 yfhD Escherichia coli CFT073 transglycosylase NP_754962.1 2958668 D 199310 CDS NP_754963.1 26248923 1038784 complement(2960221..2960757) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2559; Escherichia coli O157:H7 ortholog: z3839; tRNA-specific adenosine deaminase 2960757 yfhC 1038784 yfhC Escherichia coli CFT073 tRNA-specific adenosine deaminase NP_754963.1 2960221 R 199310 CDS NP_754964.2 161486149 1038785 complement(2960782..2961417) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2560; Escherichia coli O157:H7 ortholog: z3840; hypothetical protein 2961417 yfhB 1038785 yfhB Escherichia coli CFT073 hypothetical protein NP_754964.2 2960782 R 199310 CDS NP_754965.1 26248925 1038786 complement(2961378..2961515) 1 NC_004431.1 hypothetical protein 2961515 1038786 c3084 Escherichia coli CFT073 hypothetical protein NP_754965.1 2961378 R 199310 CDS NP_754966.2 161486148 1038788 2961626..2962474 1 NC_004431.1 Escherichia coli K-12 ortholog: b2561; Escherichia coli O157:H7 ortholog: z3841; DNA-binding transcriptional regulator 2962474 yfhH 1038788 yfhH Escherichia coli CFT073 DNA-binding transcriptional regulator NP_754966.2 2961626 D 199310 CDS NP_754967.1 26248927 1038790 2962530..2962790 1 NC_004431.1 Escherichia coli K-12 ortholog: b2562; Escherichia coli O157:H7 ortholog: z3842; ferredoxin-like protein yfhL 2962790 yfhL 1038790 yfhL Escherichia coli CFT073 ferredoxin-like protein yfhL NP_754967.1 2962530 D 199310 CDS NP_754968.1 26248928 1038791 complement(2963485..2963865) 1 NC_004431.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2963865 acpS 1038791 acpS Escherichia coli CFT073 4'-phosphopantetheinyl transferase NP_754968.1 2963485 R 199310 CDS NP_754969.1 26248929 1038793 complement(2963865..2964611) 1 NC_004431.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2964611 pdxJ 1038793 pdxJ Escherichia coli CFT073 pyridoxine 5'-phosphate synthase NP_754969.1 2963865 R 199310 CDS NP_754970.1 26248930 1038794 complement(2964608..2965336) 1 NC_004431.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2965336 recO 1038794 recO Escherichia coli CFT073 DNA repair protein RecO NP_754970.1 2964608 R 199310 CDS NP_754971.1 26248931 1038795 complement(2965348..2966253) 1 NC_004431.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2966253 era 1038795 era Escherichia coli CFT073 GTP-binding protein Era NP_754971.1 2965348 R 199310 CDS NP_754972.1 26248932 1038796 complement(2966250..2966930) 1 NC_004431.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2966930 rnc 1038796 rnc Escherichia coli CFT073 ribonuclease III NP_754972.1 2966250 R 199310 CDS NP_754973.1 26248933 1038797 complement(2967202..2968176) 1 NC_004431.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2968176 lepB 1038797 lepB Escherichia coli CFT073 signal peptidase I NP_754973.1 2967202 R 199310 CDS NP_754974.1 26248934 1038798 complement(2968192..2969991) 1 NC_004431.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2969991 lepA 1038798 lepA Escherichia coli CFT073 GTP-binding protein LepA NP_754974.1 2968192 R 199310 CDS NP_754975.1 26248935 1038799 complement(2970189..2970668) 1 NC_004431.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2970668 rseC 1038799 rseC Escherichia coli CFT073 SoxR reducing system protein RseC NP_754975.1 2970189 R 199310 CDS NP_754976.1 26248936 1038801 complement(2970665..2971621) 1 NC_004431.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 2971621 rseB 1038801 rseB Escherichia coli CFT073 periplasmic negative regulator of sigmaE NP_754976.1 2970665 R 199310 CDS NP_754977.1 26248937 1038802 complement(2971621..2972271) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2572; Escherichia coli O157:H7 ortholog: z3854; anti-RNA polymerase sigma factor SigE 2972271 rseA 1038802 rseA Escherichia coli CFT073 anti-RNA polymerase sigma factor SigE NP_754977.1 2971621 R 199310 CDS NP_754978.1 26248938 1038803 complement(2972304..2972912) 1 NC_004431.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 2972912 rpoE 1038803 rpoE Escherichia coli CFT073 RNA polymerase sigma factor RpoE NP_754978.1 2972304 R 199310 CDS NP_754979.1 26248939 1038804 2973287..2974909 1 NC_004431.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2974909 nadB 1038804 nadB Escherichia coli CFT073 L-aspartate oxidase NP_754979.1 2973287 D 199310 CDS NP_754980.1 26248940 1038805 complement(2974894..2975751) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2575; Escherichia coli O157:H7 ortholog: z3857; hypothetical protein 2975751 yfiC 1038805 yfiC Escherichia coli CFT073 hypothetical protein NP_754980.1 2974894 R 199310 CDS NP_754981.1 26248941 1038806 2975763..2977097 1 NC_004431.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2977097 srmB 1038806 srmB Escherichia coli CFT073 ATP-dependent RNA helicase SrmB NP_754981.1 2975763 D 199310 CDS NP_754982.1 26248942 1038808 complement(2977130..2978056) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2577; Escherichia coli O157:H7 ortholog: z3860; transcriptional regulator YfiE 2978056 yfiE 1038808 yfiE Escherichia coli CFT073 transcriptional regulator YfiE NP_754982.1 2977130 R 199310 CDS NP_754983.1 26248943 1038810 2978114..2978701 1 NC_004431.1 Escherichia coli K-12 ortholog: b2578; Escherichia coli O157:H7 ortholog: z3861; neutral amino-acid efflux protein 2978701 yfiK 1038810 yfiK Escherichia coli CFT073 neutral amino-acid efflux protein NP_754983.1 2978114 D 199310 CDS NP_754984.2 161486147 1038814 complement(2978757..2979140) 1 NC_004431.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2979140 yfiD 1038814 yfiD Escherichia coli CFT073 autonomous glycyl radical cofactor GrcA NP_754984.2 2978757 R 199310 CDS NP_754985.1 26248945 1038815 2978874..2979251 1 NC_004431.1 hypothetical protein 2979251 1038815 c3104 Escherichia coli CFT073 hypothetical protein NP_754985.1 2978874 D 199310 CDS NP_754986.1 26248946 1038816 2979445..2980134 1 NC_004431.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2980134 ung 1038816 ung Escherichia coli CFT073 uracil-DNA glycosylase NP_754986.1 2979445 D 199310 CDS NP_754987.2 229106374 1038820 complement(2980183..2981220) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2581; Escherichia coli O157:H7 ortholog: z3865; methyltransferase 2981220 yfiF 1038820 yfiF Escherichia coli CFT073 methyltransferase NP_754987.2 2980183 R 199310 CDS NP_754988.1 26248948 1038821 2981427..2981846 1 NC_004431.1 Escherichia coli K-12 ortholog: b2582; Escherichia coli O157:H7 ortholog: z3867; thioredoxin 2 2981846 trxC 1038821 trxC Escherichia coli CFT073 thioredoxin 2 NP_754988.1 2981427 D 199310 CDS NP_754989.1 26248949 1038822 2981864..2982613 1 NC_004431.1 Escherichia coli K-12 ortholog: b2583; Escherichia coli O157:H7 ortholog: z3868; hypothetical protein 2982613 yfiP 1038822 yfiP Escherichia coli CFT073 hypothetical protein NP_754989.1 2981864 D 199310 CDS NP_754990.1 26248950 1038824 2982645..2985305 1 NC_004431.1 Escherichia coli K-12 ortholog: b2584; Escherichia coli O157:H7 ortholog: z3869; hypothetical protein 2985305 yfiQ 1038824 yfiQ Escherichia coli CFT073 hypothetical protein NP_754990.1 2982645 D 199310 CDS NP_754991.1 26248951 1038826 2985416..2986774 1 NC_004431.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2986774 pssA 1038826 pssA Escherichia coli CFT073 phosphatidylserine synthase NP_754991.1 2985416 D 199310 CDS NP_754992.1 26248952 1038828 2986799..2987143 1 NC_004431.1 Escherichia coli K-12 ortholog: b2586; Escherichia coli O157:H7 ortholog: z3871; hypothetical protein 2987143 yfiM 1038828 yfiM Escherichia coli CFT073 hypothetical protein NP_754992.1 2986799 D 199310 CDS NP_754993.1 26248953 1038829 complement(2987140..2988531) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2587; Escherichia coli O157:H7 ortholog: z3872; alpha-ketoglutarate transporter 2988531 kgtP 1038829 kgtP Escherichia coli CFT073 alpha-ketoglutarate transporter NP_754993.1 2987140 R 199310 CDS NP_754994.1 26248954 1038838 2994127..2994261 1 NC_004431.1 hypothetical protein 2994261 1038838 c3113 Escherichia coli CFT073 hypothetical protein NP_754994.1 2994127 D 199310 CDS NP_754995.1 26248955 1038839 complement(2994301..2996886) 1 NC_004431.1 Heat shock protein F84.1; Escherichia coli K-12 ortholog: b2592; Escherichia coli O157:H7 ortholog: z3886; protein disaggregation chaperone 2996886 clpB 1038839 clpB Escherichia coli CFT073 protein disaggregation chaperone NP_754995.1 2994301 R 199310 CDS NP_754996.1 26248956 1038842 complement(2997004..2997735) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2593; Escherichia coli O157:H7 ortholog: z3887; hypothetical protein 2997735 yfiH 1038842 yfiH Escherichia coli CFT073 hypothetical protein NP_754996.1 2997004 R 199310 CDS NP_754997.1 26248957 1038843 complement(2997732..2998712) 1 NC_004431.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 2998712 rluD 1038843 rluD Escherichia coli CFT073 23S rRNA pseudouridine synthase D NP_754997.1 2997732 R 199310 CDS NP_754998.1 26248958 1038844 2998847..2999584 1 NC_004431.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2999584 yfiO 1038844 yfiO Escherichia coli CFT073 outer membrane protein assembly complex subunit YfiO NP_754998.1 2998847 D 199310 CDS NP_754999.1 26248959 1038845 complement(2999773..3000309) 1 NC_004431.1 hypothetical protein 3000309 1038845 c3118 Escherichia coli CFT073 hypothetical protein NP_754999.1 2999773 R 199310 CDS NP_755000.1 26248960 1038846 2999854..3000195 1 NC_004431.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3000195 yfiA 1038846 yfiA Escherichia coli CFT073 translation inhibitor protein RaiA NP_755000.1 2999854 D 199310 CDS NP_755002.1 26248962 1038849 3000445..3001605 1 NC_004431.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3001605 pheA 1038849 pheA Escherichia coli CFT073 bifunctional chorismate mutase/prephenate dehydratase NP_755002.1 3000445 D 199310 CDS NP_755003.1 26248963 1038850 complement(3001648..3002769) 1 NC_004431.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 3002769 tyrA 1038850 tyrA Escherichia coli CFT073 bifunctional chorismate mutase/prephenate dehydrogenase NP_755003.1 3001648 R 199310 CDS NP_755004.2 229106373 1038852 complement(3002780..3003850) 1 NC_004431.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3003850 aroF 1038852 aroF Escherichia coli CFT073 phospho-2-dehydro-3-deoxyheptonate aldolase NP_755004.2 3002780 R 199310 CDS NP_755005.1 26248965 1038853 3004042..3004425 1 NC_004431.1 URF2; Escherichia coli K-12 ortholog: b2602; Escherichia coli O157:H7 ortholog: z3895; hypothetical protein 3004425 yfiL 1038853 yfiL Escherichia coli CFT073 hypothetical protein NP_755005.1 3004042 D 199310 CDS NP_755006.1 26248966 1038854 3004572..3005090 1 NC_004431.1 Escherichia coli K-12 ortholog: b2603; Escherichia coli O157:H7 ortholog: z3897; hypothetical protein 3005090 yfiR 1038854 yfiR Escherichia coli CFT073 hypothetical protein NP_755006.1 3004572 D 199310 CDS NP_755007.1 26248967 1038855 3005080..3006306 1 NC_004431.1 Escherichia coli K-12 ortholog: b2604; Escherichia coli O157:H7 ortholog: z3898; hypothetical protein 3006306 yfiN 1038855 yfiN Escherichia coli CFT073 hypothetical protein NP_755007.1 3005080 D 199310 CDS NP_755008.1 26248968 1038857 3006322..3006804 1 NC_004431.1 Escherichia coli K-12 ortholog: b2605; Escherichia coli O157:H7 ortholog: z3899; outer membrane lipoprotein 3006804 yfiB 1038857 yfiB Escherichia coli CFT073 outer membrane lipoprotein NP_755008.1 3006322 D 199310 CDS NP_755009.1 26248969 1038858 complement(3006881..3007228) 1 NC_004431.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3007228 rplS 1038858 rplS Escherichia coli CFT073 50S ribosomal protein L19 NP_755009.1 3006881 R 199310 CDS NP_755010.1 26248970 1038859 complement(3007270..3008037) 1 NC_004431.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3008037 trmD 1038859 trmD Escherichia coli CFT073 tRNA (guanine-N(1)-)-methyltransferase NP_755010.1 3007270 R 199310 CDS NP_755011.2 161486146 1038860 complement(3008068..3008616) 1 NC_004431.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3008616 rimM 1038860 rimM Escherichia coli CFT073 16S rRNA-processing protein RimM NP_755011.2 3008068 R 199310 CDS NP_755012.2 161486145 1038861 complement(3008635..3008883) 1 NC_004431.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3008883 rpsP 1038861 rpsP Escherichia coli CFT073 30S ribosomal protein S16 NP_755012.2 3008635 R 199310 CDS NP_755013.1 26248973 1038863 complement(3009020..3010381) 1 NC_004431.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 3010381 ffh 1038863 ffh Escherichia coli CFT073 signal recognition particle protein NP_755013.1 3009020 R 199310 CDS NP_755014.1 26248974 1038864 3010473..3011339 1 NC_004431.1 Escherichia coli K-12 ortholog: b2611; Escherichia coli O157:H7 ortholog: z3905; hypothetical protein 3011339 ypjD 1038864 ypjD Escherichia coli CFT073 hypothetical protein NP_755014.1 3010473 D 199310 CDS NP_755015.2 161486144 1038865 3011450..3012646 1 NC_004431.1 Fusion of Escherichia coli K-12 B2612 and B2613; Residues 1 to 420 of 420 are 99.28 pct identical to residues 9 to 428 of 428 from SwissProt.40 : >sp|P37908|YFJD_ECOLI HYPOTHETICAL 46.4 KDA PROTEIN IN FFH-GRPE INTERGENIC REGION; hypothetical protein 3012646 1038865 c3133 Escherichia coli CFT073 hypothetical protein NP_755015.2 3011450 D 199310 CDS NP_755016.1 26248976 1038866 3012668..3013420 1 NC_004431.1 hypothetical protein 3013420 1038866 c3134 Escherichia coli CFT073 hypothetical protein NP_755016.1 3012668 D 199310 CDS NP_755017.1 26248977 1038867 complement(3012701..3013294) 1 NC_004431.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3013294 grpE 1038867 grpE Escherichia coli CFT073 heat shock protein GrpE NP_755017.1 3012701 R 199310 CDS NP_755018.1 26248978 1038868 complement(3013291..3013542) 1 NC_004431.1 Residues 30 to 83 of 83 are 100.00 pct identical to residues 10 to 63 of 63 from SwissProt.40 : >sp|P37907|YFJC_ECOLI HYPOTHETICAL 7.0 KD PROTEIN IN GRPE-RECN INTERGENIC REGION; hypothetical protein 3013542 1038868 c3136 Escherichia coli CFT073 hypothetical protein NP_755018.1 3013291 R 199310 CDS NP_755019.1 26248979 1038869 3013417..3014295 1 NC_004431.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3014295 ppnK 1038869 ppnK Escherichia coli CFT073 inorganic polyphosphate/ATP-NAD kinase NP_755019.1 3013417 D 199310 CDS NP_755020.1 26248980 1038870 3014381..3016042 1 NC_004431.1 Recombination protein N; Escherichia coli K-12 ortholog: b2616; Escherichia coli O157:H7 ortholog: z3909; recombination and repair protein 3016042 recN 1038870 recN Escherichia coli CFT073 recombination and repair protein NP_755020.1 3014381 D 199310 CDS NP_755021.1 26248981 1038872 3016191..3016532 1 NC_004431.1 Residues 1 to 113 of 113 are 100.00 pct identical to residues 1 to 113 of 113 from SwissProt.40 : >sp|P23089|SMPA_ECOLI Small protein A precursor; hypothetical protein 3016532 1038872 c3139 Escherichia coli CFT073 hypothetical protein NP_755021.1 3016191 D 199310 CDS NP_755022.2 161486143 1038873 complement(3016594..3016884) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2618; Escherichia coli O157:H7 ortholog: z3911; hypothetical protein 3016884 1038873 c3140 Escherichia coli CFT073 hypothetical protein NP_755022.2 3016594 R 199310 CDS NP_755023.1 26248983 1038874 complement(3016874..3017350) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2619; Escherichia coli O157:H7 ortholog: z3912; hypothetical protein 3017350 yfjG 1038874 yfjG Escherichia coli CFT073 hypothetical protein NP_755023.1 3016874 R 199310 CDS NP_755024.1 26248984 1038875 3017482..3017964 1 NC_004431.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3017964 smpB 1038875 smpB Escherichia coli CFT073 SsrA-binding protein NP_755024.1 3017482 D 199310 CDS NP_755025.1 26248985 1038876 3018710..3019630 1 NC_004431.1 hypothetical protein 3019630 1038876 c3143 Escherichia coli CFT073 hypothetical protein NP_755025.1 3018710 D 199310 CDS NP_755026.1 26248986 1038877 3019963..3020169 1 NC_004431.1 Escherichia coli K-12 ortholog: b1061; Escherichia coli O157:H7 ortholog: z3916; DNA-damage-inducible protein I 3020169 1038877 c3144 Escherichia coli CFT073 DNA-damage-inducible protein I NP_755026.1 3019963 D 199310 CDS NP_755027.1 26248987 1038878 3020745..3021011 1 NC_004431.1 Escherichia coli K-12 ortholog: b1544; hypothetical protein 3021011 ydfK 1038878 ydfK Escherichia coli CFT073 hypothetical protein NP_755027.1 3020745 D 199310 CDS NP_755028.1 26248988 1038880 3021386..3021976 1 NC_004431.1 Escherichia coli K-12 ortholog: b1374; Escherichia coli O157:H7 ortholog: z5885; DNA-invertase from lambdoid prophage Rac 3021976 1038880 c3146 Escherichia coli CFT073 DNA-invertase from lambdoid prophage Rac NP_755028.1 3021386 D 199310 CDS NP_755029.1 26248989 1038881 complement(3022204..3022497) 1 NC_004431.1 hypothetical protein 3022497 1038881 c3147 Escherichia coli CFT073 hypothetical protein NP_755029.1 3022204 R 199310 CDS NP_755030.1 26248990 1038882 complement(3022540..3023580) 1 NC_004431.1 Residues 110 to 233 of 346 are 31.25 pct identical to residues 486 to 611 of 669 from GenPept.129 : >gb|AAD03286.1| (AF063097) gpH [Enterobacteria phage P2]; hypothetical protein 3023580 1038882 c3148 Escherichia coli CFT073 hypothetical protein NP_755030.1 3022540 R 199310 CDS NP_755031.1 26248991 1038884 complement(3023590..3023871) 1 NC_004431.1 hypothetical protein 3023871 1038884 c3149 Escherichia coli CFT073 hypothetical protein NP_755031.1 3023590 R 199310 CDS NP_755032.1 26248992 1038885 complement(3023868..3026297) 1 NC_004431.1 Residues 118 to 438 of 809 are 30.28 pct identical to residues 291 to 638 of 973 from GenPept.129 : >gb|AAG56007.1|AE005333_4 (AE005333) membrane protein of prophage CP-933X [Escherichia coli O157:H7 EDL933]; hypothetical protein 3026297 1038885 c3150 Escherichia coli CFT073 hypothetical protein NP_755032.1 3023868 R 199310 CDS NP_755033.1 26248993 1038886 3025462..3025902 1 NC_004431.1 Residues 15 to 146 of 146 are 45.32 pct identical to residues 36 to 174 of 206 from SwissProt.40 : >sp|P03774|Y206_LAMBD HYPOTHETICAL PROTEIN ORF206; hypothetical protein 3025902 1038886 c3151 Escherichia coli CFT073 hypothetical protein NP_755033.1 3025462 D 199310 CDS NP_755034.1 26248994 1038888 complement(3026388..3026897) 1 NC_004431.1 Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 3026897 1038888 c3152 Escherichia coli CFT073 hypothetical protein NP_755034.1 3026388 R 199310 CDS NP_755035.1 26248995 1038889 complement(3027043..3027642) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1917; outer membrane protein of prophage 3027642 1038889 c3153 Escherichia coli CFT073 outer membrane protein of prophage NP_755035.1 3027043 R 199310 CDS NP_755036.1 26248996 1038891 complement(3027710..3031189) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2145; tail component of prophage 3031189 1038891 c3154 Escherichia coli CFT073 tail component of prophage NP_755036.1 3027710 R 199310 CDS NP_755037.1 26248997 1038892 complement(3031250..3031882) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0979; tail component of prophage 3031882 1038892 c3155 Escherichia coli CFT073 tail component of prophage NP_755037.1 3031250 R 199310 CDS NP_755038.1 26248998 1038893 complement(3031819..3032604) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3081; tail fiber component K of prophage 3032604 1038893 c3156 Escherichia coli CFT073 tail fiber component K of prophage NP_755038.1 3031819 R 199310 CDS NP_755039.1 26248999 1038895 3032561..3033367 1 NC_004431.1 hypothetical protein 3033367 1038895 c3157 Escherichia coli CFT073 hypothetical protein NP_755039.1 3032561 D 199310 CDS NP_755040.1 26249000 1038898 complement(3032567..3033265) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0977; tail component of prophage 3033265 1038898 c3158 Escherichia coli CFT073 tail component of prophage NP_755040.1 3032567 R 199310 CDS NP_755041.1 26249001 1038899 complement(3033265..3033594) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2353; tail component of prophage 3033594 1038899 c3159 Escherichia coli CFT073 tail component of prophage NP_755041.1 3033265 R 199310 CDS NP_755042.1 26249002 1038900 complement(3033591..3036152) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2140; tail component of prophage 3036152 1038900 c3160 Escherichia coli CFT073 tail component of prophage NP_755042.1 3033591 R 199310 CDS NP_755043.1 26249003 1038902 complement(3036145..3036579) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1896; tail component of prophage 3036579 1038902 c3161 Escherichia coli CFT073 tail component of prophage NP_755043.1 3036145 R 199310 CDS NP_755044.1 26249004 1038904 complement(3036561..3036983) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1895; tail component of prophage 3036983 1038904 c3162 Escherichia coli CFT073 tail component of prophage NP_755044.1 3036561 R 199310 CDS NP_755045.1 26249005 1038906 complement(3036999..3037769) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1894; tail component of prophage 3037769 1038906 c3163 Escherichia coli CFT073 tail component of prophage NP_755045.1 3036999 R 199310 CDS NP_755046.1 26249006 1038907 complement(3037747..3038142) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1893; tail component of prophage 3038142 1038907 c3164 Escherichia coli CFT073 tail component of prophage NP_755046.1 3037747 R 199310 CDS NP_755047.1 26249007 1038909 complement(3038139..3038717) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3089; tail fiber component Z of prophage 3038717 1038909 c3165 Escherichia coli CFT073 tail fiber component Z of prophage NP_755047.1 3038139 R 199310 CDS NP_755048.1 26249008 1038910 complement(3038729..3039082) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage 3039082 1038910 c3166 Escherichia coli CFT073 head-tail joining protein of prophage NP_755048.1 3038729 R 199310 CDS NP_755049.1 26249009 1038913 complement(3039094..3039528) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1889; DNA packaging protein of prophage 3039528 1038913 c3167 Escherichia coli CFT073 DNA packaging protein of prophage NP_755049.1 3039094 R 199310 CDS NP_755050.1 26249010 1038914 complement(3039531..3040556) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 3040556 1038914 c3168 Escherichia coli CFT073 capsid protein of prophage NP_755050.1 3039531 R 199310 CDS NP_755051.1 26249011 1038916 complement(3040611..3040949) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1887; head-DNA stabilization protein of prophage 3040949 1038916 c3169 Escherichia coli CFT073 head-DNA stabilization protein of prophage NP_755051.1 3040611 R 199310 CDS NP_755052.1 26249012 1038917 complement(3040953..3042386) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1886; capsid protein of prophage 3042386 1038917 c3170 Escherichia coli CFT073 capsid protein of prophage NP_755052.1 3040953 R 199310 CDS NP_755053.1 26249013 1038918 complement(3042253..3043854) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1885; capsid structural protein of prophage 3043854 1038918 c3171 Escherichia coli CFT073 capsid structural protein of prophage NP_755053.1 3042253 R 199310 CDS NP_755054.1 26249014 1038920 complement(3043851..3044057) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1884; head-tail joining protein of prophage 3044057 1038920 c3172 Escherichia coli CFT073 head-tail joining protein of prophage NP_755054.1 3043851 R 199310 CDS NP_755055.1 26249015 1038921 complement(3044054..3045979) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1883; DNA packaging protein of prophage 3045979 1038921 c3173 Escherichia coli CFT073 DNA packaging protein of prophage NP_755055.1 3044054 R 199310 CDS NP_755056.1 26249016 1038922 complement(3045954..3046499) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0560; Escherichia coli O157:H7 ortholog: z1882; prophage qsr' DNA packaging protein NU1-like protein 3046499 nohB 1038922 nohB Escherichia coli CFT073 prophage qsr' DNA packaging protein NU1-like protein NP_755056.1 3045954 R 199310 CDS NP_755057.1 26249017 1038923 3046059..3046598 1 NC_004431.1 Residues 1 to 179 of 179 are 78.21 pct identical to residues 1 to 179 of 179 from GenPept.129 : >gb|AAB40756.1| (U82598) hypothetical protein [Escherichia coli]; hypothetical protein 3046598 1038923 c3175 Escherichia coli CFT073 hypothetical protein NP_755057.1 3046059 D 199310 CDS NP_755058.3 347357885 1038925 complement(3047835..3048101) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1550; GnsB protein 3048101 1038925 c3176 Escherichia coli CFT073 GnsB protein NP_755058.3 3047835 R 199310 CDS NP_755059.1 26249019 1038926 complement(3048683..3048898) 1 NC_004431.1 CSP-I; Escherichia coli K-12 ortholog: b1552; Escherichia coli O157:H7 ortholog: z1406; cold shock-like protein cspI 3048898 cspI 1038926 cspI Escherichia coli CFT073 cold shock-like protein cspI NP_755059.1 3048683 R 199310 CDS NP_755060.1 26249020 1038927 complement(3048917..3049075) 1 NC_004431.1 hypothetical protein 3049075 1038927 c3178 Escherichia coli CFT073 hypothetical protein NP_755060.1 3048917 R 199310 CDS NP_755061.1 26249021 1038928 complement(3049260..3049757) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1553; hypothetical protein 3049757 ydfP 1038928 ydfP Escherichia coli CFT073 hypothetical protein NP_755061.1 3049260 R 199310 CDS NP_755062.1 26249022 1038929 complement(3049754..3050287) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1554; Escherichia coli O157:H7 ortholog: z1796; lysozyme from lambdoid prophage Qin 3050287 1038929 c3180 Escherichia coli CFT073 lysozyme from lambdoid prophage Qin NP_755062.1 3049754 R 199310 CDS NP_755063.1 26249023 1038930 complement(3050609..3051181) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2070; hypothetical protein 3051181 1038930 c3181 Escherichia coli CFT073 hypothetical protein NP_755063.1 3050609 R 199310 CDS NP_755064.1 26249024 1038932 complement(3051165..3051380) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1556; Escherichia coli O157:H7 ortholog: z3340; lambdoid prophage Qin lysis protein S 3051380 1038932 c3182 Escherichia coli CFT073 lambdoid prophage Qin lysis protein S NP_755064.1 3051165 R 199310 CDS NP_755065.1 26249025 1038933 complement(3051753..3051884) 1 NC_004431.1 hypothetical protein 3051884 1038933 c3183 Escherichia coli CFT073 hypothetical protein NP_755065.1 3051753 R 199310 CDS NP_755066.1 26249026 1038935 complement(3052133..3052348) 1 NC_004431.1 CSP-B; Escherichia coli K-12 ortholog: b1557; Escherichia coli O157:H7 ortholog: z4981; cold shock-like protein cspB 3052348 cspB 1038935 cspB Escherichia coli CFT073 cold shock-like protein cspB NP_755066.1 3052133 R 199310 CDS NP_755067.1 26249027 1038936 3052649..3052861 1 NC_004431.1 CSP-F; Escherichia coli K-12 ortholog: b1558; Escherichia coli O157:H7 ortholog: z1405; cold shock-like protein cspF 3052861 cspF 1038936 cspF Escherichia coli CFT073 cold shock-like protein cspF NP_755067.1 3052649 D 199310 CDS NP_755068.1 26249028 1038937 complement(3053277..3054059) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1559; Escherichia coli O157:H7 ortholog: z1345; lambdoid prophage Qin antitermination protein Q 3054059 1038937 c3186 Escherichia coli CFT073 lambdoid prophage Qin antitermination protein Q NP_755068.1 3053277 R 199310 CDS NP_755069.1 26249029 1038938 complement(3054043..3055038) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1560; Escherichia coli O157:H7 ortholog: z2100; hypothetical protein 3055038 1038938 c3187 Escherichia coli CFT073 hypothetical protein NP_755069.1 3054043 R 199310 CDS NP_755070.1 26249030 1038939 complement(3055040..3055837) 1 NC_004431.1 Residues 1 to 265 of 265 are 88.84 pct identical to residues 1 to 269 of 269 from GenPept.129 : >gb|AAL89446.1| (U82619) unknown [Shigella flexneri bacteriophage V]; hypothetical protein 3055837 1038939 c3188 Escherichia coli CFT073 hypothetical protein NP_755070.1 3055040 R 199310 CDS NP_755071.1 26249031 1038940 complement(3055857..3056246) 1 NC_004431.1 Residues 1 to 129 of 129 are 97.67 pct identical to residues 1 to 129 of 129 from GenPept.129 : >gb|AAL89445.1| (U82619) crossover junction endodeoxyribonuclease [Shigella flexneri bacteriophage V]; hypothetical protein 3056246 1038940 c3189 Escherichia coli CFT073 hypothetical protein NP_755071.1 3055857 R 199310 CDS NP_755072.1 26249032 1038941 complement(3056243..3056602) 1 NC_004431.1 Residues 12 to 119 of 119 are 95.37 pct identical to residues 1 to 108 of 108 from GenPept.129 : >gb|AAL89444.1| (U82619) unknown [Shigella flexneri bacteriophage V]; hypothetical protein 3056602 1038941 c3190 Escherichia coli CFT073 hypothetical protein NP_755072.1 3056243 R 199310 CDS NP_755073.1 26249033 1038942 complement(3056569..3057063) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2357; hypothetical protein 3057063 yfdN 1038942 yfdN Escherichia coli CFT073 hypothetical protein NP_755073.1 3056569 R 199310 CDS NP_755074.1 26249034 1038943 complement(3057060..3058001) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z6070; hypothetical protein 3058001 1038943 c3192 Escherichia coli CFT073 hypothetical protein NP_755074.1 3057060 R 199310 CDS NP_755077.1 26249037 1038948 complement(3058346..3058954) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1147; hypothetical protein 3058954 ymfL 1038948 ymfL Escherichia coli CFT073 hypothetical protein NP_755077.1 3058346 R 199310 CDS NP_755078.1 26249038 1038949 complement(3058935..3059135) 1 NC_004431.1 Residues 1 to 65 of 66 are 53.84 pct identical to residues 1 to 65 of 75 from GenPept.129 : >dbj|BAB36188.1| (AP002559) cell division control protein [Escherichia coli O157:H7]; hypothetical protein 3059135 1038949 c3196 Escherichia coli CFT073 hypothetical protein NP_755078.1 3058935 R 199310 CDS NP_755079.1 26249039 1038953 3059233..3059859 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3126; repressor protein of prophage 3059859 1038953 c3197 Escherichia coli CFT073 repressor protein of prophage NP_755079.1 3059233 D 199310 CDS NP_755080.1 26249040 1038954 complement(3060075..3060587) 1 NC_004431.1 hypothetical protein 3060587 1038954 c3198 Escherichia coli CFT073 hypothetical protein NP_755080.1 3060075 R 199310 CDS NP_755081.1 26249041 1038955 complement(3060560..3061243) 1 NC_004431.1 Residues 181 to 211 of 227 are 74.19 pct identical to residues 1 to 31 of 210 from GenPept.129 : >gb|AAG55872.1|AE005322_6 (AE005322) unknown protein encoded by prophage CP-933N [Escherichia coli O157:H7 EDL933]; hypothetical protein 3061243 1038955 c3199 Escherichia coli CFT073 hypothetical protein NP_755081.1 3060560 R 199310 CDS NP_755082.1 26249042 1038956 3060731..3061417 1 NC_004431.1 Residues 103 to 228 of 228 are 97.61 pct identical to residues 23 to 148 of 148 from GenPept.129 : >gb|AAC75418.1| (AE000324) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 3061417 1038956 c3200 Escherichia coli CFT073 hypothetical protein NP_755082.1 3060731 D 199310 CDS NP_755083.1 26249043 1038957 3061483..3062307 1 NC_004431.1 Escherichia coli K-12 ortholog: b2360; hypothetical protein 3062307 yfdQ 1038957 yfdQ Escherichia coli CFT073 hypothetical protein NP_755083.1 3061483 D 199310 CDS NP_755084.1 26249044 1038958 3062408..3062959 1 NC_004431.1 Escherichia coli K-12 ortholog: b2361; hypothetical protein 3062959 yfdR 1038958 yfdR Escherichia coli CFT073 hypothetical protein NP_755084.1 3062408 D 199310 CDS NP_755085.1 26249045 1038959 3063044..3063934 1 NC_004431.1 hypothetical protein 3063934 1038959 c3203 Escherichia coli CFT073 hypothetical protein NP_755085.1 3063044 D 199310 CDS NP_755086.1 26249046 1038960 3064143..3065315 1 NC_004431.1 Residues 12 to 376 of 390 are 31.39 pct identical to residues 4 to 373 of 389 from GenPept.129 : >gb|AAG09988.1|AF251497_6 (AF251497) integrase [Cloning vector HKBS1]; hypothetical protein 3065315 1038960 c3204 Escherichia coli CFT073 hypothetical protein NP_755086.1 3064143 D 199310 CDS NP_755087.1 26249047 1038961 complement(3065329..3065718) 1 NC_004431.1 Residues 3 to 126 of 129 are 32.35 pct identical to residues 1 to 135 of 142 from GenPept.129 : >emb|CAD05563.1| (AL627272) bacteriophage protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 3065718 1038961 c3205 Escherichia coli CFT073 hypothetical protein NP_755087.1 3065329 R 199310 CDS NP_755088.1 26249048 1038963 complement(3065702..3066517) 1 NC_004431.1 hypothetical protein 3066517 1038963 c3206 Escherichia coli CFT073 hypothetical protein NP_755088.1 3065702 R 199310 CDS NP_755089.1 26249049 1038966 3067657..3068634 1 NC_004431.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3068634 ygaT 1038966 ygaT Escherichia coli CFT073 hypothetical protein NP_755089.1 3067657 D 199310 CDS NP_755090.1 26249050 1038967 3068588..3069922 1 NC_004431.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3069922 ygaF 1038967 ygaF Escherichia coli CFT073 hydroxyglutarate oxidase NP_755090.1 3068588 D 199310 CDS NP_755091.1 26249051 1038968 3069945..3071393 1 NC_004431.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3071393 gabD 1038968 gabD Escherichia coli CFT073 succinate-semialdehyde dehydrogenase I NP_755091.1 3069945 D 199310 CDS NP_755092.1 26249052 1038970 3071401..3072687 1 NC_004431.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3072687 gabT 1038970 gabT Escherichia coli CFT073 4-aminobutyrate aminotransferase NP_755092.1 3071401 D 199310 CDS NP_755093.3 347357884 1038972 3072861..3074324 1 NC_004431.1 4-amino butyrate transport carrier; Escherichia coli K-12 ortholog: b2663; Escherichia coli O157:H7 ortholog: z3961; gamma-aminobutyrate transporter 3074324 gabP 1038972 gabP Escherichia coli CFT073 gamma-aminobutyrate transporter NP_755093.3 3072861 D 199310 CDS NP_755094.2 161486140 1038973 3074345..3075007 1 NC_004431.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3075007 ygaE 1038973 ygaE Escherichia coli CFT073 DNA-binding transcriptional regulator CsiR NP_755094.2 3074345 D 199310 CDS NP_755095.1 26249055 1038974 complement(3075008..3075457) 1 NC_004431.1 Spot LM6; Escherichia coli K-12 ortholog: b2665; Escherichia coli O157:H7 ortholog: z3964; LysM domain/BON superfamily protein 3075457 ygaU 1038974 ygaU Escherichia coli CFT073 LysM domain/BON superfamily protein NP_755095.1 3075008 R 199310 CDS NP_755096.1 26249056 1038975 3075529..3075714 1 NC_004431.1 hypothetical protein 3075714 1038975 c3214 Escherichia coli CFT073 hypothetical protein NP_755096.1 3075529 D 199310 CDS NP_755097.1 26249057 1038976 complement(3075541..3075699) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2666; Escherichia coli O157:H7 ortholog: z3965; hypothetical protein 3075699 yqaE 1038976 yqaE Escherichia coli CFT073 hypothetical protein NP_755097.1 3075541 R 199310 CDS NP_755098.1 26249058 1038978 3075882..3076181 1 NC_004431.1 Escherichia coli K-12 ortholog: b2667; Escherichia coli O157:H7 ortholog: z3966; transcriptional regulator YgaV 3076181 ygaV 1038978 ygaV Escherichia coli CFT073 transcriptional regulator YgaV NP_755098.1 3075882 D 199310 CDS NP_755099.1 26249059 1038979 3076191..3076715 1 NC_004431.1 Escherichia coli K-12 ortholog: b2668; Escherichia coli O157:H7 ortholog: z3967; hypothetical protein 3076715 ygaP 1038979 ygaP Escherichia coli CFT073 hypothetical protein NP_755099.1 3076191 D 199310 CDS NP_755100.1 26249060 1038981 complement(3076762..3077166) 1 NC_004431.1 H-NS homolog stpA; Escherichia coli K-12 ortholog: b2669; Escherichia coli O157:H7 ortholog: z3968; DNA binding protein, nucleoid-associated 3077166 stpA 1038981 stpA Escherichia coli CFT073 DNA binding protein, nucleoid-associated NP_755100.1 3076762 R 199310 CDS NP_755101.1 26249061 1038982 complement(3077328..3077459) 1 NC_004431.1 hypothetical protein 3077459 1038982 c3219 Escherichia coli CFT073 hypothetical protein NP_755101.1 3077328 R 199310 CDS NP_755102.1 26249062 1038983 3077579..3077707 1 NC_004431.1 hypothetical protein 3077707 1038983 c3220 Escherichia coli CFT073 hypothetical protein NP_755102.1 3077579 D 199310 CDS NP_755103.1 26249063 1038984 3077833..3078282 1 NC_004431.1 Escherichia coli K-12 ortholog: b2670; Escherichia coli O157:H7 ortholog: z3970; hypothetical protein 3078282 ygaW 1038984 ygaW Escherichia coli CFT073 hypothetical protein NP_755103.1 3077833 D 199310 CDS NP_755104.1 26249064 1038985 complement(3078319..3078663) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2671; Escherichia coli O157:H7 ortholog: z3971; hypothetical protein 3078663 ygaC 1038985 ygaC Escherichia coli CFT073 hypothetical protein NP_755104.1 3078319 R 199310 CDS NP_755105.1 26249065 1038986 3078803..3079144 1 NC_004431.1 Escherichia coli K-12 ortholog: b2672; Escherichia coli O157:H7 ortholog: z3972; hypothetical protein 3079144 ygaM 1038986 ygaM Escherichia coli CFT073 hypothetical protein NP_755105.1 3078803 D 199310 CDS NP_755106.1 26249066 1038987 complement(3079201..3080535) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3973; hypothetical protein 3080535 1038987 c3224 Escherichia coli CFT073 hypothetical protein NP_755106.1 3079201 R 199310 CDS NP_755107.1 26249067 1038989 3080623..3081108 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3974; hypothetical protein 3081108 1038989 c3225 Escherichia coli CFT073 hypothetical protein NP_755107.1 3080623 D 199310 CDS NP_755108.1 26249068 1038990 3081260..3081505 1 NC_004431.1 Escherichia coli K-12 ortholog: b2673; Escherichia coli O157:H7 ortholog: z3975; glutaredoxin-like protein 3081505 nrdH 1038990 nrdH Escherichia coli CFT073 glutaredoxin-like protein NP_755108.1 3081260 D 199310 CDS NP_755109.1 26249069 1038992 3081502..3081912 1 NC_004431.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3081912 nrdI 1038992 nrdI Escherichia coli CFT073 ribonucleotide reductase stimulatory protein NP_755109.1 3081502 D 199310 CDS NP_755110.1 26249070 1038993 3081885..3084029 1 NC_004431.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3084029 nrdE 1038993 nrdE Escherichia coli CFT073 ribonucleotide-diphosphate reductase subunit alpha NP_755110.1 3081885 D 199310 CDS NP_755111.1 26249071 1038994 3084039..3084998 1 NC_004431.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3084998 nrdF 1038994 nrdF Escherichia coli CFT073 ribonucleotide-diphosphate reductase subunit beta NP_755111.1 3084039 D 199310 CDS NP_755112.1 26249072 1038995 3085355..3086557 1 NC_004431.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3086557 proV 1038995 proV Escherichia coli CFT073 glycine betaine transporter ATP-binding subunit NP_755112.1 3085355 D 199310 CDS NP_755113.1 26249073 1038997 3086550..3087614 1 NC_004431.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3087614 proW 1038997 proW Escherichia coli CFT073 glycine betaine transporter membrane protein NP_755113.1 3086550 D 199310 CDS NP_755114.2 161486139 1038998 3087671..3088663 1 NC_004431.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3088663 proX 1038998 proX Escherichia coli CFT073 glycine betaine transporter periplasmic subunit NP_755114.2 3087671 D 199310 CDS NP_755115.1 26249075 1038999 3088716..3088862 1 NC_004431.1 hypothetical protein 3088862 1038999 c3233 Escherichia coli CFT073 hypothetical protein NP_755115.1 3088716 D 199310 CDS NP_755116.1 26249076 1039000 3088855..3090039 1 NC_004431.1 Escherichia coli K-12 ortholog: b2681; Escherichia coli O157:H7 ortholog: z3982; transport protein 3090039 1039000 c3234 Escherichia coli CFT073 transport protein NP_755116.1 3088855 D 199310 CDS NP_755117.1 26249077 1039001 3090164..3090901 1 NC_004431.1 Escherichia coli K-12 ortholog: b2682; Escherichia coli O157:H7 ortholog: z3983; hypothetical protein 3090901 ygaZ 1039001 ygaZ Escherichia coli CFT073 hypothetical protein NP_755117.1 3090164 D 199310 CDS NP_755118.1 26249078 1039002 3090891..3091226 1 NC_004431.1 Escherichia coli K-12 ortholog: b2683; Escherichia coli O157:H7 ortholog: z3984; hypothetical protein 3091226 ygaH 1039002 ygaH Escherichia coli CFT073 hypothetical protein NP_755118.1 3090891 D 199310 CDS NP_755119.1 26249079 1039003 3091317..3091847 1 NC_004431.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3091847 emrR 1039003 emrR Escherichia coli CFT073 transcriptional repressor MprA NP_755119.1 3091317 D 199310 CDS NP_755120.1 26249080 1039005 3091962..3093146 1 NC_004431.1 Escherichia coli K-12 ortholog: b2685; Escherichia coli O157:H7 ortholog: z3986; multidrug resistance protein A 3093146 emrA 1039005 emrA Escherichia coli CFT073 multidrug resistance protein A NP_755120.1 3091962 D 199310 CDS NP_755121.1 26249081 1039006 3093154..3094701 1 NC_004431.1 Escherichia coli K-12 ortholog: b2686; Escherichia coli O157:H7 ortholog: z3987; multidrug resistance protein B 3094701 emrB 1039006 emrB Escherichia coli CFT073 multidrug resistance protein B NP_755121.1 3093154 D 199310 CDS NP_755122.1 26249082 1039009 3094959..3095315 1 NC_004431.1 Residues 6 to 115 of 118 are 38.18 pct identical to residues 4 to 111 of 210 from GenPept.129 : >gb|AAF12618.1|AE001826_87 (AE001826) hypothetical protein [Deinococcus radiodurans]; hypothetical protein 3095315 1039009 c3240 Escherichia coli CFT073 hypothetical protein NP_755122.1 3094959 D 199310 CDS NP_755123.1 26249083 1039011 complement(3095055..3095450) 1 NC_004431.1 hypothetical protein 3095450 1039011 c3241 Escherichia coli CFT073 hypothetical protein NP_755123.1 3095055 R 199310 CDS NP_755124.1 26249084 1039012 3095327..3095656 1 NC_004431.1 hypothetical protein 3095656 1039012 c3242 Escherichia coli CFT073 hypothetical protein NP_755124.1 3095327 D 199310 CDS NP_755125.1 26249085 1039013 3095653..3096765 1 NC_004431.1 Residues 16 to 359 of 370 are 37.50 pct identical to residues 19 to 360 of 363 from GenPept.129 : >gb|AAK78729.1|AE007591_2 (AE007591) PolyA polymerase related protein (HD hydrolase) and P-loop ATP-ase domain [Clostridium acetobutylicum]; hypothetical protein 3096765 1039013 c3243 Escherichia coli CFT073 hypothetical protein NP_755125.1 3095653 D 199310 CDS NP_755126.1 26249086 1039014 complement(3096814..3097329) 1 NC_004431.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 3097329 ygaG 1039014 ygaG Escherichia coli CFT073 S-ribosylhomocysteinase NP_755126.1 3096814 R 199310 CDS NP_755127.1 26249087 1039015 complement(3097479..3099035) 1 NC_004431.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 3099035 gshA 1039015 gshA Escherichia coli CFT073 glutamate--cysteine ligase NP_755127.1 3097479 R 199310 CDS NP_755128.1 26249088 1039017 complement(3099108..3099536) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2689; Escherichia coli O157:H7 ortholog: z3990; hypothetical protein 3099536 yqaA 1039017 yqaA Escherichia coli CFT073 hypothetical protein NP_755128.1 3099108 R 199310 CDS NP_755129.1 26249089 1039018 complement(3099533..3100099) 1 NC_004431.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 3100099 yqaB 1039018 yqaB Escherichia coli CFT073 fructose-1-phosphatase NP_755129.1 3099533 R 199310 CDS NP_755130.1 26249090 1039019 complement(3100129..3100254) 1 NC_004431.1 hypothetical protein 3100254 1039019 c3248 Escherichia coli CFT073 hypothetical protein NP_755130.1 3100129 R 199310 CDS NP_755131.1 26249091 1039032 complement(3101427..3101612) 1 NC_004431.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3101612 csrA 1039032 csrA Escherichia coli CFT073 carbon storage regulator NP_755131.1 3101427 R 199310 CDS NP_755132.1 26249092 1039035 3104383..3104553 1 NC_004431.1 Residues 1 to 50 of 56 are 92.00 pct identical to residues 74 to 123 of 133 from GenPept.129 : >gb|AAG57802.1|AE005498_3 (AE005498) Z4000 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 3104553 1039035 c3251 Escherichia coli CFT073 hypothetical protein NP_755132.1 3104383 D 199310 CDS NP_755133.1 26249093 1039039 complement(3104607..3105107) 1 NC_004431.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3105107 recX 1039039 recX Escherichia coli CFT073 recombination regulator RecX NP_755133.1 3104607 R 199310 CDS NP_755134.1 26249094 1039040 complement(3105176..3106237) 1 NC_004431.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3106237 recA 1039040 recA Escherichia coli CFT073 recombinase A NP_755134.1 3105176 R 199310 CDS NP_755135.1 26249095 1039043 complement(3106317..3106817) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2700; Escherichia coli O157:H7 ortholog: z4003; competence damage-inducible protein A 3106817 ygaD 1039043 ygaD Escherichia coli CFT073 competence damage-inducible protein A NP_755135.1 3106317 R 199310 CDS NP_755136.1 26249096 1039044 complement(3106959..3108149) 1 NC_004431.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 3108149 mltB 1039044 mltB Escherichia coli CFT073 murein hydrolase B NP_755136.1 3106959 R 199310 CDS NP_755137.1 26249097 1039046 3108301..3108864 1 NC_004431.1 EIIC2-GUT; Escherichia coli K-12 ortholog: b2702; Escherichia coli O157:H7 ortholog: z4005; PTS system, glucitol/sorbitol-specific IIC2 component 3108864 srlA 1039046 srlA Escherichia coli CFT073 PTS system, glucitol/sorbitol-specific IIC2 component NP_755137.1 3108301 D 199310 CDS NP_755138.1 26249098 1039048 3108861..3109820 1 NC_004431.1 EIIBC-GUT; Escherichia coli K-12 ortholog: b2703; Escherichia coli O157:H7 ortholog: z4009; PTS system, glucitol/sorbitol-specific IIBC component 3109820 srlE 1039048 srlE Escherichia coli CFT073 PTS system, glucitol/sorbitol-specific IIBC component NP_755138.1 3108861 D 199310 CDS NP_755139.1 26249099 1039049 3109831..3110202 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3110202 srlB 1039049 srlB Escherichia coli CFT073 PTS system glucitol/sorbitol-specific transporter subunit IIA NP_755139.1 3109831 D 199310 CDS NP_755140.1 26249100 1039050 3110206..3110985 1 NC_004431.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3110985 srlD 1039050 srlD Escherichia coli CFT073 sorbitol-6-phosphate dehydrogenase NP_755140.1 3110206 D 199310 CDS NP_755141.1 26249101 1039051 3111091..3111450 1 NC_004431.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3111450 gutM 1039051 gutM Escherichia coli CFT073 DNA-binding transcriptional activator GutM NP_755141.1 3111091 D 199310 CDS NP_755142.1 26249102 1039052 3111517..3112290 1 NC_004431.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3112290 srlR 1039052 srlR Escherichia coli CFT073 DNA-binding transcriptional repressor SrlR NP_755142.1 3111517 D 199310 CDS NP_755143.1 26249103 1039055 3112283..3113248 1 NC_004431.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3113248 gutQ 1039055 gutQ Escherichia coli CFT073 D-arabinose 5-phosphate isomerase NP_755143.1 3112283 D 199310 CDS NP_755144.2 161486138 1039057 complement(3113245..3114759) 1 NC_004431.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator 3114759 ygaA 1039057 ygaA Escherichia coli CFT073 anaerobic nitric oxide reductase transcription regulator NP_755144.2 3113245 R 199310 CDS NP_755145.1 26249105 1039058 complement(3114916..3115959) 1 NC_004431.1 Residues 288 to 347 of 347 are 94.99 pct identical to residues 1 to 60 of 60 from GenPept.129 : >gb|AAA92664.1| (U03846) ORF >60AA [Escherichia coli]; hypothetical protein 3115959 1039058 c3264 Escherichia coli CFT073 hypothetical protein NP_755145.1 3114916 R 199310 CDS NP_755146.1 26249106 1039063 3116383..3117516 1 NC_004431.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3117516 ygbD 1039063 ygbD Escherichia coli CFT073 nitric oxide reductase NP_755146.1 3116383 D 199310 CDS NP_755147.1 26249107 1039064 complement(3117740..3120064) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2712; Escherichia coli O157:H7 ortholog: z4020; hydrogenase maturation protein hypF 3120064 hypF 1039064 hypF Escherichia coli CFT073 hydrogenase maturation protein hypF NP_755147.1 3117740 R 199310 CDS NP_755148.1 26249108 1039066 complement(3120145..3120687) 1 NC_004431.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 3120687 hydN 1039066 hydN Escherichia coli CFT073 electron transport protein HydN NP_755148.1 3120145 R 199310 CDS NP_755149.1 26249109 1039067 complement(3120766..3120951) 1 NC_004431.1 hypothetical protein 3120951 1039067 c3270 Escherichia coli CFT073 hypothetical protein NP_755149.1 3120766 R 199310 CDS NP_755150.1 26249110 1039068 3121057..3121485 1 NC_004431.1 hypothetical protein 3121485 1039068 c3271 Escherichia coli CFT073 hypothetical protein NP_755150.1 3121057 D 199310 CDS NP_755151.1 26249111 1039070 complement(3121448..3121573) 1 NC_004431.1 hypothetical protein 3121573 1039070 c3272 Escherichia coli CFT073 hypothetical protein NP_755151.1 3121448 R 199310 CDS NP_755152.1 26249112 1039071 complement(3121577..3121996) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3082; Escherichia coli O157:H7 ortholog: z4435; hypothetical protein 3121996 1039071 c3273 Escherichia coli CFT073 hypothetical protein NP_755152.1 3121577 R 199310 CDS NP_755153.1 26249113 1039073 complement(3121993..3122304) 1 NC_004431.1 Residues 1 to 103 of 103 are 58.25 pct identical to residues 1 to 103 of 103 from GenPept.129 : >gb|AAL22870.1| (AE008888) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 3122304 1039073 c3274 Escherichia coli CFT073 hypothetical protein NP_755153.1 3121993 R 199310 CDS NP_755154.1 26249114 1039074 3122041..3122232 1 NC_004431.1 hypothetical protein 3122232 1039074 c3275 Escherichia coli CFT073 hypothetical protein NP_755154.1 3122041 D 199310 CDS NP_755155.1 26249115 1039075 complement(3122467..3123240) 1 NC_004431.1 Residues 12 to 257 of 257 are 72.17 pct identical to residues 22 to 269 of 269 from GenPept.129 : >gb|AAL21724.1| (AE008830) periplasmic or exported protein [Salmonella typhimurium LT2]; hypothetical protein 3123240 1039075 c3276 Escherichia coli CFT073 hypothetical protein NP_755155.1 3122467 R 199310 CDS NP_755156.1 26249116 1039079 complement(3123265..3123735) 1 NC_004431.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3123735 hycI 1039079 hycI Escherichia coli CFT073 hydrogenase 3 maturation protease NP_755156.1 3123265 R 199310 CDS NP_755157.1 26249117 1039080 complement(3123728..3124138) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2718; Escherichia coli O157:H7 ortholog: z4026; formate hydrogenlyase maturation protein hycH 3124138 hycH 1039080 hycH Escherichia coli CFT073 formate hydrogenlyase maturation protein hycH NP_755157.1 3123728 R 199310 CDS NP_755158.1 26249118 1039081 complement(3124135..3124902) 1 NC_004431.1 FHL subunit 7; Escherichia coli K-12 ortholog: b2719; Escherichia coli O157:H7 ortholog: z4027; formate hydrogenlyase subunit 7 3124902 hycG 1039081 hycG Escherichia coli CFT073 formate hydrogenlyase subunit 7 NP_755158.1 3124135 R 199310 CDS NP_755159.1 26249119 1039083 complement(3124902..3125444) 1 NC_004431.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3125444 hycF 1039083 hycF Escherichia coli CFT073 formate hydrogenlyase complex iron-sulfur subunit NP_755159.1 3124902 R 199310 CDS NP_755160.1 26249120 1039084 complement(3125454..3127163) 1 NC_004431.1 FHL subunit 5; Escherichia coli K-12 ortholog: b2721; Escherichia coli O157:H7 ortholog: z4029; formate hydrogenlyase subunit 5 3127163 hycE 1039084 hycE Escherichia coli CFT073 formate hydrogenlyase subunit 5 NP_755160.1 3125454 R 199310 CDS NP_755161.1 26249121 1039085 complement(3127181..3128104) 1 NC_004431.1 FHL subunit 4; Escherichia coli K-12 ortholog: b2722; Escherichia coli O157:H7 ortholog: z4030; formate hydrogenlyase subunit 4 3128104 hycD 1039085 hycD Escherichia coli CFT073 formate hydrogenlyase subunit 4 NP_755161.1 3127181 R 199310 CDS NP_755162.1 26249122 1039087 complement(3128107..3129933) 1 NC_004431.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3129933 hycC 1039087 hycC Escherichia coli CFT073 formate hydrogenlyase subunit 3 NP_755162.1 3128107 R 199310 CDS NP_755163.1 26249123 1039088 complement(3129930..3130541) 1 NC_004431.1 FHL subunit 2; Escherichia coli K-12 ortholog: b2724; Escherichia coli O157:H7 ortholog: z4032; formate hydrogenlyase subunit 2 3130541 hycB 1039088 hycB Escherichia coli CFT073 formate hydrogenlyase subunit 2 NP_755163.1 3129930 R 199310 CDS NP_755164.1 26249124 1039089 complement(3130666..3131127) 1 NC_004431.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3131127 hycA 1039089 hycA Escherichia coli CFT073 formate hydrogenlyase regulatory protein HycA NP_755164.1 3130666 R 199310 CDS NP_755165.1 26249125 1039090 3131327..3131689 1 NC_004431.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3131689 hypA 1039090 hypA Escherichia coli CFT073 hydrogenase nickel incorporation protein NP_755165.1 3131327 D 199310 CDS NP_755166.1 26249126 1039092 3131693..3132565 1 NC_004431.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3132565 hypB 1039092 hypB Escherichia coli CFT073 hydrogenase nickel incorporation protein HypB NP_755166.1 3131693 D 199310 CDS NP_755167.1 26249127 1039093 3132556..3132828 1 NC_004431.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3132828 hypC 1039093 hypC Escherichia coli CFT073 hydrogenase assembly chaperone NP_755167.1 3132556 D 199310 CDS NP_755168.1 26249128 1039094 3132828..3133949 1 NC_004431.1 Escherichia coli K-12 ortholog: b2729; Escherichia coli O157:H7 ortholog: z4038; hydrogenase isoenzyme formation protein hypD 3133949 hypD 1039094 hypD Escherichia coli CFT073 hydrogenase isoenzyme formation protein hypD NP_755168.1 3132828 D 199310 CDS NP_755169.1 26249129 1039095 3133946..3134956 1 NC_004431.1 Escherichia coli K-12 ortholog: b2730; Escherichia coli O157:H7 ortholog: z4039; hydrogenase isoenzyme formation protein hypE 3134956 hypE 1039095 hypE Escherichia coli CFT073 hydrogenase isoenzyme formation protein hypE NP_755169.1 3133946 D 199310 CDS NP_755170.1 26249130 1039096 3134994..3137108 1 NC_004431.1 Escherichia coli K-12 ortholog: b2731; Escherichia coli O157:H7 ortholog: z4040; formate hydrogenlyase transcriptional activator 3137108 fhlA 1039096 fhlA Escherichia coli CFT073 formate hydrogenlyase transcriptional activator NP_755170.1 3134994 D 199310 CDS NP_755171.1 26249131 1039098 3137114..3137581 1 NC_004431.1 Residues 14 to 155 of 155 are 48.59 pct identical to residues 1 to 142 of 142 from GenPept.129 : >emb|CAA90038.1| (Z49882) potential molybdenum-pterin-binding-protein [Azotobacter vinelandii]; molybdenum-pterin-binding-protein 3137581 1039098 c3292 Escherichia coli CFT073 molybdenum-pterin-binding-protein NP_755171.1 3137114 D 199310 CDS NP_755172.1 26249132 1039099 complement(3137620..3137964) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2732; Escherichia coli O157:H7 ortholog: z4041; hypothetical protein 3137964 ygbA 1039099 ygbA Escherichia coli CFT073 hypothetical protein NP_755172.1 3137620 R 199310 CDS NP_755173.1 26249133 1039100 3138250..3140811 1 NC_004431.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3140811 mutS 1039100 mutS Escherichia coli CFT073 DNA mismatch repair protein MutS NP_755173.1 3138250 D 199310 CDS NP_755174.1 26249134 1039101 3140917..3141573 1 NC_004431.1 Escherichia coli K-12 ortholog: b2734; Escherichia coli O157:H7 ortholog: z4044; serine/threonine-specific protein phosphatase 2 3141573 pphB 1039101 pphB Escherichia coli CFT073 serine/threonine-specific protein phosphatase 2 NP_755174.1 3140917 D 199310 CDS NP_755175.1 26249135 1039105 complement(3141624..3142421) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2735; transcriptional regulator YgbI 3142421 ygbI 1039105 ygbI Escherichia coli CFT073 transcriptional regulator YgbI NP_755175.1 3141624 R 199310 CDS NP_755176.1 26249136 1039107 3142587..3143495 1 NC_004431.1 Escherichia coli K-12 ortholog: b2736; oxidoreductase ygbJ 3143495 ygbJ 1039107 ygbJ Escherichia coli CFT073 oxidoreductase ygbJ NP_755176.1 3142587 D 199310 CDS NP_755177.1 26249137 1039109 3143492..3144754 1 NC_004431.1 Escherichia coli K-12 ortholog: b2737; hypothetical protein 3144754 ygbK 1039109 ygbK Escherichia coli CFT073 hypothetical protein NP_755177.1 3143492 D 199310 CDS NP_755178.1 26249138 1039110 3144751..3145389 1 NC_004431.1 Escherichia coli K-12 ortholog: b2738; aldolase 3145389 ygbL 1039110 ygbL Escherichia coli CFT073 aldolase NP_755178.1 3144751 D 199310 CDS NP_755179.1 26249139 1039111 3145394..3146170 1 NC_004431.1 Escherichia coli K-12 ortholog: b2739; Escherichia coli O157:H7 ortholog: z0662; hypothetical protein 3146170 ygbM 1039111 ygbM Escherichia coli CFT073 hypothetical protein NP_755179.1 3145394 D 199310 CDS NP_755180.1 26249140 1039112 3146259..3147623 1 NC_004431.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3147623 ygbN 1039112 ygbN Escherichia coli CFT073 inner membrane permease YgbN NP_755180.1 3146259 D 199310 CDS NP_755181.1 26249141 1039115 complement(3147766..3148809) 1 NC_004431.1 Residues 1 to 347 of 347 are 100.00 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAG27179.1|AF270497_4 (AF270497) unknown [Escherichia coli]; hypothetical protein 3148809 1039115 c3302 Escherichia coli CFT073 hypothetical protein NP_755181.1 3147766 R 199310 CDS NP_755182.1 26249142 1039118 3148828..3148974 1 NC_004431.1 hypothetical protein 3148974 1039118 c3303 Escherichia coli CFT073 hypothetical protein NP_755182.1 3148828 D 199310 CDS NP_755183.1 26249143 1039119 3149034..3149585 1 NC_004431.1 Residues 1 to 183 of 183 are 100.00 pct identical to residues 1 to 183 of 183 from GenPept.129 : >gb|AAG27178.1|AF270497_3 (AF270497) unknown [Escherichia coli]; hypothetical protein 3149585 1039119 c3304 Escherichia coli CFT073 hypothetical protein NP_755183.1 3149034 D 199310 CDS NP_755184.1 26249144 1039120 3149703..3150329 1 NC_004431.1 hypothetical protein 3150329 1039120 c3305 Escherichia coli CFT073 hypothetical protein NP_755184.1 3149703 D 199310 CDS NP_755185.1 26249145 1039121 complement(3149763..3150281) 1 NC_004431.1 Residues 1 to 172 of 172 are 100.00 pct identical to residues 159 to 330 of 330 from GenPept.129 : >gb|AAL01414.1|AF410777_1 (AF410777) RpoS [Escherichia coli]; hypothetical protein 3150281 1039121 c3306 Escherichia coli CFT073 hypothetical protein NP_755185.1 3149763 R 199310 CDS NP_755186.1 26249146 1039124 complement(3150362..3150796) 1 NC_004431.1 Residues 13 to 144 of 144 are 99.24 pct identical to residues 1 to 132 of 330 from MG1655 : b2741; hypothetical protein 3150796 1039124 c3307 Escherichia coli CFT073 hypothetical protein NP_755186.1 3150362 R 199310 CDS NP_755187.1 26249147 1039128 complement(3150823..3151962) 1 NC_004431.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3151962 nlpD 1039128 nlpD Escherichia coli CFT073 lipoprotein NlpD NP_755187.1 3150823 R 199310 CDS NP_755188.1 26249148 1039129 3151820..3151987 1 NC_004431.1 hypothetical protein 3151987 1039129 c3309 Escherichia coli CFT073 hypothetical protein NP_755188.1 3151820 D 199310 CDS NP_755189.1 26249149 1039130 complement(3152102..3152728) 1 NC_004431.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3152728 pcm 1039130 pcm Escherichia coli CFT073 protein-L-isoaspartate O-methyltransferase NP_755189.1 3152102 R 199310 CDS NP_755190.1 26249150 1039131 complement(3152722..3153528) 1 NC_004431.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3153528 surE 1039131 surE Escherichia coli CFT073 stationary phase survival protein SurE NP_755190.1 3152722 R 199310 CDS NP_755191.1 26249151 1039133 complement(3153464..3154513) 1 NC_004431.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3154513 truD 1039133 truD Escherichia coli CFT073 tRNA pseudouridine synthase D NP_755191.1 3153464 R 199310 CDS NP_755192.1 26249152 1039136 complement(3154510..3154989) 1 NC_004431.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3154989 ispF 1039136 ispF Escherichia coli CFT073 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_755192.1 3154510 R 199310 CDS NP_755193.1 26249153 1039137 complement(3154989..3155699) 1 NC_004431.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3155699 ispD 1039137 ispD Escherichia coli CFT073 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_755193.1 3154989 R 199310 CDS NP_755194.1 26249154 1039142 complement(3155718..3156029) 1 NC_004431.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3156029 ftsB 1039142 ftsB Escherichia coli CFT073 cell division protein FtsB NP_755194.1 3155718 R 199310 CDS NP_755195.1 26249155 1039143 complement(3156222..3156545) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2749; Escherichia coli O157:H7 ortholog: z4057; hypothetical protein 3156545 ygbE 1039143 ygbE Escherichia coli CFT073 hypothetical protein NP_755195.1 3156222 R 199310 CDS NP_755196.1 26249156 1039145 complement(3156597..3157202) 1 NC_004431.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3157202 cysC 1039145 cysC Escherichia coli CFT073 adenylylsulfate kinase NP_755196.1 3156597 R 199310 CDS NP_755197.1 26249157 1039146 complement(3157202..3158629) 1 NC_004431.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3158629 cysN 1039146 cysN Escherichia coli CFT073 sulfate adenylyltransferase subunit 1 NP_755197.1 3157202 R 199310 CDS NP_755198.1 26249158 1039147 complement(3158631..3159539) 1 NC_004431.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3159539 cysD 1039147 cysD Escherichia coli CFT073 sulfate adenylyltransferase subunit 2 NP_755198.1 3158631 R 199310 CDS NP_755199.1 26249159 1039149 3159791..3160828 1 NC_004431.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3160828 iap 1039149 iap Escherichia coli CFT073 alkaline phosphatase NP_755199.1 3159791 D 199310 CDS NP_755200.1 26249160 1039150 complement(3161370..3162104) 1 NC_004431.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3162104 cysH 1039150 cysH Escherichia coli CFT073 phosphoadenosine phosphosulfate reductase NP_755200.1 3161370 R 199310 CDS NP_755201.1 26249161 1039153 complement(3162178..3163890) 1 NC_004431.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3163890 cysI 1039153 cysI Escherichia coli CFT073 sulfite reductase subunit beta NP_755201.1 3162178 R 199310 CDS NP_755202.1 26249162 1039155 complement(3163890..3165689) 1 NC_004431.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3165689 cysJ 1039155 cysJ Escherichia coli CFT073 sulfite reductase subunit alpha NP_755202.1 3163890 R 199310 CDS NP_755203.1 26249163 1039156 3165921..3166370 1 NC_004431.1 Escherichia coli K-12 ortholog: b2765; Escherichia coli O157:H7 ortholog: z4075; 6-pyruvoyl tetrahydrobiopterin synthase 3166370 ygcM 1039156 ygcM Escherichia coli CFT073 6-pyruvoyl tetrahydrobiopterin synthase NP_755203.1 3165921 D 199310 CDS NP_755204.1 26249164 1039157 3166418..3167719 1 NC_004431.1 Escherichia coli K-12 ortholog: b2766; Escherichia coli O157:H7 ortholog: z4076; electron transfer flavoprotein-quinone oxidoreductase ygcN 3167719 ygcN 1039157 ygcN Escherichia coli CFT073 electron transfer flavoprotein-quinone oxidoreductase ygcN NP_755204.1 3166418 D 199310 CDS NP_755205.1 26249165 1039158 3167674..3167970 1 NC_004431.1 Escherichia coli K-12 ortholog: b2767; Escherichia coli O157:H7 ortholog: z4077; ferredoxin-like protein ygcO 3167970 ygcO 1039158 ygcO Escherichia coli CFT073 ferredoxin-like protein ygcO NP_755205.1 3167674 D 199310 CDS NP_755206.1 26249166 1039160 complement(3168711..3169604) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2769; Escherichia coli O157:H7 ortholog: z4080; electron transfer flavoprotein subunit ygcQ 3169604 ygcQ 1039160 ygcQ Escherichia coli CFT073 electron transfer flavoprotein subunit ygcQ NP_755206.1 3168711 R 199310 CDS NP_755207.1 26249167 1039161 complement(3169568..3170350) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2770; Escherichia coli O157:H7 ortholog: z4081; electron transfer flavoprotein subunit ygcR 3170350 ygcR 1039161 ygcR Escherichia coli CFT073 electron transfer flavoprotein subunit ygcR NP_755207.1 3169568 R 199310 CDS NP_755208.1 26249168 1039163 complement(3170322..3171731) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2771; Escherichia coli O157:H7 ortholog: z4083; metabolite transport protein 3171731 ygcS 1039163 ygcS Escherichia coli CFT073 metabolite transport protein NP_755208.1 3170322 R 199310 CDS NP_755209.1 26249169 1039164 complement(3171753..3173207) 1 NC_004431.1 Residues 221 to 484 of 484 are 98.10 pct identical to residues 1 to 264 of 264 from MG1655 : b2772; hypothetical protein 3173207 1039164 c3331 Escherichia coli CFT073 hypothetical protein NP_755209.1 3171753 R 199310 CDS NP_755210.1 26249170 1039165 complement(3173277..3174137) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2774; Escherichia coli O157:H7 ortholog: z4085; oxidoreductase ygcW 3174137 ygcW 1039165 ygcW Escherichia coli CFT073 oxidoreductase ygcW NP_755210.1 3173277 R 199310 CDS NP_755211.1 26249171 1039168 3174381..3175658 1 NC_004431.1 Escherichia coli K-12 ortholog: b2775; Escherichia coli O157:H7 ortholog: z4086; hypothetical protein 3175658 yqcE 1039168 yqcE Escherichia coli CFT073 hypothetical protein NP_755211.1 3174381 D 199310 CDS NP_755212.1 26249172 1039170 3175685..3177163 1 NC_004431.1 Escherichia coli K-12 ortholog: b2776; Escherichia coli O157:H7 ortholog: z4087; sugar kinase ygcE 3177163 ygcE 1039170 ygcE Escherichia coli CFT073 sugar kinase ygcE NP_755212.1 3175685 D 199310 CDS NP_755213.1 26249173 1039171 complement(3177637..3178308) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2777; Escherichia coli O157:H7 ortholog: z4089; hypothetical protein 3178308 ygcF 1039171 ygcF Escherichia coli CFT073 hypothetical protein NP_755213.1 3177637 R 199310 CDS NP_755214.1 26249174 1039172 3178342..3178467 1 NC_004431.1 hypothetical protein 3178467 1039172 c3336 Escherichia coli CFT073 hypothetical protein NP_755214.1 3178342 D 199310 CDS NP_755215.1 26249175 1039173 3178481..3179083 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4090; hypothetical protein 3179083 1039173 c3337 Escherichia coli CFT073 hypothetical protein NP_755215.1 3178481 D 199310 CDS NP_755216.1 26249176 1039174 3179067..3179990 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4091; hypothetical protein 3179990 1039174 c3338 Escherichia coli CFT073 hypothetical protein NP_755216.1 3179067 D 199310 CDS NP_755217.1 26249177 1039176 complement(3179594..3179884) 1 NC_004431.1 hypothetical protein 3179884 1039176 c3339 Escherichia coli CFT073 hypothetical protein NP_755217.1 3179594 R 199310 CDS NP_755218.1 26249178 1039178 3180005..3181159 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4092; hypothetical protein 3181159 1039178 c3340 Escherichia coli CFT073 hypothetical protein NP_755218.1 3180005 D 199310 CDS YP_004853817.1 347357936 1039179 3180532..3180699 1 NC_004431.1 hypothetical protein 3180699 1039179 c3341 Escherichia coli CFT073 hypothetical protein YP_004853817.1 3180532 D 199310 CDS NP_755220.1 26249180 1039180 3181153..3182037 1 NC_004431.1 Escherichia coli K-12 ortholog: b2778; Escherichia coli O157:H7 ortholog: z4093; hypothetical protein 3182037 ygcG 1039180 ygcG Escherichia coli CFT073 hypothetical protein NP_755220.1 3181153 D 199310 CDS NP_755221.1 26249181 1039182 3182052..3183281 1 NC_004431.1 hypothetical protein 3183281 1039182 c3343 Escherichia coli CFT073 hypothetical protein NP_755221.1 3182052 D 199310 CDS NP_755222.1 26249182 1039183 complement(3182097..3183395) 1 NC_004431.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3183395 eno 1039183 eno Escherichia coli CFT073 phosphopyruvate hydratase NP_755222.1 3182097 R 199310 CDS NP_755223.1 26249183 1039184 complement(3183483..3185120) 1 NC_004431.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3185120 pyrG 1039184 pyrG Escherichia coli CFT073 CTP synthetase NP_755223.1 3183483 R 199310 CDS NP_755224.1 26249184 1039187 complement(3185348..3186139) 1 NC_004431.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3186139 mazG 1039187 mazG Escherichia coli CFT073 nucleoside triphosphate pyrophosphohydrolase NP_755224.1 3185348 R 199310 CDS NP_755225.1 26249185 1039188 complement(3186235..3188469) 1 NC_004431.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3188469 relA 1039188 relA Escherichia coli CFT073 GDP/GTP pyrophosphokinase NP_755225.1 3186235 R 199310 CDS NP_755226.1 26249186 1039189 complement(3188517..3189818) 1 NC_004431.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3189818 rumA 1039189 rumA Escherichia coli CFT073 23S rRNA 5-methyluridine methyltransferase NP_755226.1 3188517 R 199310 CDS NP_755227.1 26249187 1039190 3189875..3192631 1 NC_004431.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3192631 barA 1039190 barA Escherichia coli CFT073 hybrid sensory histidine kinase BarA NP_755227.1 3189875 D 199310 CDS NP_755228.1 26249188 1039191 complement(3192862..3193989) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2787; Escherichia coli O157:H7 ortholog: z4102; glucarate dehydratase 3193989 ygcX 1039191 ygcX Escherichia coli CFT073 glucarate dehydratase NP_755228.1 3192862 R 199310 CDS NP_755229.1 26249189 1039192 complement(3194225..3195565) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2788; Escherichia coli O157:H7 ortholog: z4103; glucarate dehydratase-like protein 3195565 ygcY 1039192 ygcY Escherichia coli CFT073 glucarate dehydratase-like protein NP_755229.1 3194225 R 199310 CDS NP_755230.1 26249190 1039193 complement(3195567..3196919) 1 NC_004431.1 D-glucarate permease; Escherichia coli K-12 ortholog: b2789; Escherichia coli O157:H7 ortholog: z4105; glucarate transporter 3196919 1039193 c3353 Escherichia coli CFT073 glucarate transporter NP_755230.1 3195567 R 199310 CDS NP_755231.1 26249191 1039194 complement(3197012..3197137) 1 NC_004431.1 hypothetical protein 3197137 1039194 c3354 Escherichia coli CFT073 hypothetical protein NP_755231.1 3197012 R 199310 CDS NP_755232.1 26249192 1039195 3197131..3197259 1 NC_004431.1 hypothetical protein 3197259 1039195 c3355 Escherichia coli CFT073 hypothetical protein NP_755232.1 3197131 D 199310 CDS NP_755233.1 26249193 1039196 complement(3197352..3197801) 1 NC_004431.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3197801 yqcA 1039196 yqcA Escherichia coli CFT073 flavodoxin NP_755233.1 3197352 R 199310 CDS NP_755234.1 26249194 1039197 complement(3197819..3198601) 1 NC_004431.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3198601 yqcB 1039197 yqcB Escherichia coli CFT073 tRNA pseudouridine synthase C NP_755234.1 3197819 R 199310 CDS NP_755235.1 26249195 1039199 complement(3198601..3198930) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2792; Escherichia coli O157:H7 ortholog: z4108; hypothetical protein 3198930 yqcC 1039199 yqcC Escherichia coli CFT073 hypothetical protein NP_755235.1 3198601 R 199310 CDS NP_755236.1 26249196 1039202 complement(3199552..3200097) 1 NC_004431.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3200097 syd 1039202 syd Escherichia coli CFT073 SecY interacting protein Syd NP_755236.1 3199552 R 199310 CDS NP_755237.1 26249197 1039203 3200165..3201013 1 NC_004431.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3201013 queF 1039203 queF Escherichia coli CFT073 7-cyano-7-deazaguanine reductase NP_755237.1 3200165 D 199310 CDS NP_755238.1 26249198 1039204 3201125..3202489 1 NC_004431.1 Escherichia coli K-12 ortholog: b2795; Escherichia coli O157:H7 ortholog: z4112; hypothetical protein 3202489 ygdH 1039204 ygdH Escherichia coli CFT073 hypothetical protein NP_755238.1 3201125 D 199310 CDS NP_755239.1 26249199 1039205 3202573..3202704 1 NC_004431.1 hypothetical protein 3202704 1039205 c3362 Escherichia coli CFT073 hypothetical protein NP_755239.1 3202573 D 199310 CDS NP_755240.1 26249200 1039206 complement(3203019..3204446) 1 NC_004431.1 hypothetical protein 3204446 1039206 c3363 Escherichia coli CFT073 hypothetical protein NP_755240.1 3203019 R 199310 CDS NP_755241.1 26249201 1039208 3203046..3204335 1 NC_004431.1 Escherichia coli K-12 ortholog: b2796; Escherichia coli O157:H7 ortholog: z4113; Serine transporter 3204335 sdaC 1039208 sdaC Escherichia coli CFT073 Serine transporter NP_755241.1 3203046 D 199310 CDS NP_755242.1 26249202 1039211 3204393..3205760 1 NC_004431.1 Escherichia coli K-12 ortholog: b2797; Escherichia coli O157:H7 ortholog: z4114; L-serine dehydratase 2 3205760 sdaB 1039211 sdaB Escherichia coli CFT073 L-serine dehydratase 2 NP_755242.1 3204393 D 199310 CDS NP_755243.1 26249203 1039213 3205782..3206627 1 NC_004431.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3206627 xni 1039213 xni Escherichia coli CFT073 exonuclease IX NP_755243.1 3205782 D 199310 CDS NP_755244.1 26249204 1039215 complement(3206732..3207883) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2799; Escherichia coli O157:H7 ortholog: z4116; L-1,2-propanediol oxidoreductase 3207883 fucO 1039215 fucO Escherichia coli CFT073 L-1,2-propanediol oxidoreductase NP_755244.1 3206732 R 199310 CDS NP_755245.1 26249205 1039216 complement(3207908..3208555) 1 NC_004431.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3208555 fucA 1039216 fucA Escherichia coli CFT073 L-fuculose phosphate aldolase NP_755245.1 3207908 R 199310 CDS NP_755246.1 26249206 1039219 3208745..3208882 1 NC_004431.1 hypothetical protein 3208882 1039219 c3369 Escherichia coli CFT073 hypothetical protein NP_755246.1 3208745 D 199310 CDS NP_755247.1 26249207 1039220 3209102..3210418 1 NC_004431.1 Escherichia coli K-12 ortholog: b2801; Escherichia coli O157:H7 ortholog: z4118; L-fucose transporter 3210418 fucP 1039220 fucP Escherichia coli CFT073 L-fucose transporter NP_755247.1 3209102 D 199310 CDS NP_755248.1 26249208 1039222 3210451..3212226 1 NC_004431.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3212226 fucI 1039222 fucI Escherichia coli CFT073 L-fucose isomerase NP_755248.1 3210451 D 199310 CDS NP_755249.1 26249209 1039226 3213754..3214176 1 NC_004431.1 Escherichia coli K-12 ortholog: b2804; Escherichia coli O157:H7 ortholog: z4121; fucose operon fucU protein 3214176 fucU 1039226 fucU Escherichia coli CFT073 fucose operon fucU protein NP_755249.1 3213754 D 199310 CDS NP_755250.1 26249210 1039228 3214225..3214965 1 NC_004431.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3214965 fucR 1039228 fucR Escherichia coli CFT073 DNA-binding transcriptional activator FucR NP_755250.1 3214225 D 199310 CDS NP_755251.1 26249211 1039229 complement(3215009..3216109) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2806; Escherichia coli O157:H7 ortholog: z4123; RNA 2'-O-ribose methyltransferase 3216109 ygdE 1039229 ygdE Escherichia coli CFT073 RNA 2'-O-ribose methyltransferase NP_755251.1 3215009 R 199310 CDS NP_755252.1 26249212 1039230 complement(3216102..3216404) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2807; Escherichia coli O157:H7 ortholog: z4124; hypothetical protein 3216404 ygdD 1039230 ygdD Escherichia coli CFT073 hypothetical protein NP_755252.1 3216102 R 199310 CDS NP_755253.1 26249213 1039231 complement(3216516..3217433) 1 NC_004431.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3217433 gcvA 1039231 gcvA Escherichia coli CFT073 DNA-binding transcriptional activator GcvA NP_755253.1 3216516 R 199310 CDS NP_755254.1 26249214 1039232 3217751..3218044 1 NC_004431.1 hypothetical protein 3218044 1039232 c3379 Escherichia coli CFT073 hypothetical protein NP_755254.1 3217751 D 199310 CDS NP_755255.1 26249215 1039233 complement(3217784..3218014) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2809; Escherichia coli O157:H7 ortholog: z4126; lipoprotein ygdI 3218014 ygdI 1039233 ygdI Escherichia coli CFT073 lipoprotein ygdI NP_755255.1 3217784 R 199310 CDS NP_755256.1 26249216 1039234 3218167..3219408 1 NC_004431.1 Escherichia coli K-12 ortholog: b2810; Escherichia coli O157:H7 ortholog: z4127; cysteine sulfinate desulfinase 3219408 1039234 c3381 Escherichia coli CFT073 cysteine sulfinate desulfinase NP_755256.1 3218167 D 199310 CDS NP_755257.1 26249217 1039235 3219408..3219851 1 NC_004431.1 Escherichia coli K-12 ortholog: b2811; Escherichia coli O157:H7 ortholog: z4128; hypothetical protein 3219851 ygdK 1039235 ygdK Escherichia coli CFT073 hypothetical protein NP_755257.1 3219408 D 199310 CDS NP_755258.1 26249218 1039236 complement(3219902..3220708) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2812; Escherichia coli O157:H7 ortholog: z4129; hypothetical protein 3220708 ygdL 1039236 ygdL Escherichia coli CFT073 hypothetical protein NP_755258.1 3219902 R 199310 CDS NP_755259.2 161486137 1039237 complement(3220785..3221882) 1 NC_004431.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3221882 mltA 1039237 mltA Escherichia coli CFT073 murein transglycosylase A NP_755259.2 3220785 R 199310 CDS NP_755260.1 26249220 1039245 3223002..3223523 1 NC_004431.1 Residues 9 to 171 of 173 are 73.61 pct identical to residues 3 to 165 of 166 from GenPept.129 : >emb|CAC90290.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3223523 1039245 c3385 Escherichia coli CFT073 hypothetical protein NP_755260.1 3223002 D 199310 CDS NP_755261.1 26249221 1039247 3223576..3225120 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0262; hypothetical protein 3225120 1039247 c3386 Escherichia coli CFT073 hypothetical protein NP_755261.1 3223576 D 199310 CDS NP_755262.1 26249222 1039248 3225140..3226477 1 NC_004431.1 Residues 1 to 444 of 445 are 59.33 pct identical to residues 1 to 449 of 450 from GenPept.129 : >emb|CAC89820.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3226477 1039248 c3387 Escherichia coli CFT073 hypothetical protein NP_755262.1 3225140 D 199310 CDS NP_755263.1 26249223 1039249 3226474..3227139 1 NC_004431.1 Residues 8 to 218 of 221 are 51.38 pct identical to residues 13 to 226 of 228 from GenPept.129 : >emb|CAC90293.1| (AJ414148) membrane protein [Yersinia pestis]; hypothetical protein 3227139 1039249 c3388 Escherichia coli CFT073 hypothetical protein NP_755263.1 3226474 D 199310 CDS NP_755264.1 26249224 1039252 3227152..3228804 1 NC_004431.1 Residues 6 to 550 of 550 are 41.51 pct identical to residues 6 to 562 of 578 from GenPept.129 : >emb|CAC90294.1| (AJ414148) exported protein [Yersinia pestis]; hypothetical protein 3228804 1039252 c3389 Escherichia coli CFT073 hypothetical protein NP_755264.1 3227152 D 199310 CDS NP_755265.1 26249225 1039253 complement(3228841..3229443) 1 NC_004431.1 hypothetical protein 3229443 1039253 c3390 Escherichia coli CFT073 hypothetical protein NP_755265.1 3228841 R 199310 CDS NP_755266.1 26249226 1039254 3228862..3229353 1 NC_004431.1 Residues 1 to 163 of 163 are 83.43 pct identical to residues 1 to 163 of 163 from GenPept.129 : >emb|CAC90295.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; secreted protein Hcp 3229353 1039254 c3391 Escherichia coli CFT073 secreted protein Hcp NP_755266.1 3228862 D 199310 CDS NP_755267.1 26249227 1039255 3229545..3232181 1 NC_004431.1 Heat shock protein F84.1; Escherichia coli K-12 ortholog: b2592; Escherichia coli O157:H7 ortholog: z0254; ClpB protein 3232181 1039255 c3392 Escherichia coli CFT073 ClpB protein NP_755267.1 3229545 D 199310 CDS NP_755268.1 26249228 1039256 3232181..3234655 1 NC_004431.1 Residues 10 to 743 of 824 are 62.75 pct identical to residues 10 to 749 of 782 from GenPept.129 : >emb|CAC89815.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3234655 1039256 c3393 Escherichia coli CFT073 hypothetical protein NP_755268.1 3232181 D 199310 CDS NP_755269.1 26249229 1039257 3234670..3235494 1 NC_004431.1 hypothetical protein 3235494 1039257 c3394 Escherichia coli CFT073 hypothetical protein NP_755269.1 3234670 D 199310 CDS NP_755270.1 26249230 1039259 3235491..3237467 1 NC_004431.1 Residues 30 to 634 of 658 are 31.40 pct identical to residues 41 to 639 of 746 from GenPept.129 : >emb|CAD14662.1| (AL646061) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 3237467 1039259 c3395 Escherichia coli CFT073 hypothetical protein NP_755270.1 3235491 D 199310 CDS NP_755271.1 26249231 1039260 3237477..3237749 1 NC_004431.1 Residues 7 to 83 of 90 are 37.66 pct identical to residues 15 to 91 of 101 from GenPept.129 : >emb|CAC89712.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3237749 1039260 c3396 Escherichia coli CFT073 hypothetical protein NP_755271.1 3237477 D 199310 CDS NP_755272.1 26249232 1039263 3237749..3239182 1 NC_004431.1 hypothetical protein 3239182 1039263 c3397 Escherichia coli CFT073 hypothetical protein NP_755272.1 3237749 D 199310 CDS NP_755273.1 26249233 1039264 3239189..3242527 1 NC_004431.1 Residues 78 to 1111 of 1112 are 50.43 pct identical to residues 97 to 1136 of 1140 from GenPept.129 : >emb|CAC90304.1| (AJ414148) membrane protein [Yersinia pestis]; hypothetical protein 3242527 1039264 c3398 Escherichia coli CFT073 hypothetical protein NP_755273.1 3239189 D 199310 CDS NP_755274.1 26249234 1039266 3242493..3244130 1 NC_004431.1 Residues 10 to 539 of 545 are 60.82 pct identical to residues 1 to 532 of 533 from GenPept.129 : >emb|CAC90305.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein 3244130 1039266 c3399 Escherichia coli CFT073 hypothetical protein NP_755274.1 3242493 D 199310 CDS NP_755275.1 26249235 1039267 3244161..3246965 1 NC_004431.1 Residues 2 to 539 of 934 are 73.33 pct identical to residues 1 to 539 of 587 from GenPept.129 : >emb|CAC90308.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3246965 1039267 c3400 Escherichia coli CFT073 hypothetical protein NP_755275.1 3244161 D 199310 CDS NP_755276.1 26249236 1039268 3246946..3247482 1 NC_004431.1 Residues 19 to 172 of 178 are 47.77 pct identical to residues 1 to 157 of 162 from GenPept.129 : >emb|CAC90310.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3247482 1039268 c3401 Escherichia coli CFT073 hypothetical protein NP_755276.1 3246946 D 199310 CDS NP_755277.1 26249237 1039270 3247486..3247914 1 NC_004431.1 Residues 2 to 138 of 142 are 59.12 pct identical to residues 5 to 141 of 150 from GenPept.129 : >emb|CAC90311.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3247914 1039270 c3402 Escherichia coli CFT073 hypothetical protein NP_755277.1 3247486 D 199310 CDS NP_755278.1 26249238 1039271 3247914..3249290 1 NC_004431.1 Residues 14 to 450 of 458 are 40.91 pct identical to residues 12 to 449 of 455 from GenPept.129 : >emb|CAC90312.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein 3249290 1039271 c3403 Escherichia coli CFT073 hypothetical protein NP_755278.1 3247914 D 199310 CDS NP_755279.1 26249239 1039272 complement(3248464..3248616) 1 NC_004431.1 hypothetical protein 3248616 1039272 c3404 Escherichia coli CFT073 hypothetical protein NP_755279.1 3248464 R 199310 CDS NP_755280.1 26249240 1039273 complement(3249590..3250546) 1 NC_004431.1 Residues 5 to 318 of 318 are 37.77 pct identical to residues 3 to 317 of 317 from GenPept.129 : >gb|AAK90773.1| (AE007909) AGR_pAT_578p [Agrobacterium tumefaciens str. C58 (Cereon)]; 2-hydroxyacid dehydrogenase 3250546 1039273 c3405 Escherichia coli CFT073 2-hydroxyacid dehydrogenase NP_755280.1 3249590 R 199310 CDS NP_755281.1 26249241 1039274 complement(3250609..3251205) 1 NC_004431.1 Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546; phosphosugar isomerase 3251205 1039274 c3406 Escherichia coli CFT073 phosphosugar isomerase NP_755281.1 3250609 R 199310 CDS NP_755282.1 26249242 1039276 complement(3251208..3252383) 1 NC_004431.1 Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]; Beta-cystathionase 3252383 1039276 c3407 Escherichia coli CFT073 Beta-cystathionase NP_755282.1 3251208 R 199310 CDS NP_755283.1 26249243 1039277 complement(3252383..3253963) 1 NC_004431.1 Maltose and glucose-permease IIABC component; Escherichia coli K-12 ortholog: b1621; Escherichia coli O157:H7 ortholog: z2626; PTS system, maltose and glucose-specific IIABC component 3253963 1039277 c3408 Escherichia coli CFT073 PTS system, maltose and glucose-specific IIABC component NP_755283.1 3252383 R 199310 CDS NP_755284.1 26249244 1039278 complement(3253995..3254876) 1 NC_004431.1 Residues 1 to 293 of 293 are 98.63 pct identical to residues 1 to 293 of 293 from GenPept.129 : >gb|AAC61733.1| (AF081286) sacpa operon antiterminator R1 [Escherichia coli]; antiterminator 3254876 1039278 c3409 Escherichia coli CFT073 antiterminator NP_755284.1 3253995 R 199310 CDS NP_755285.1 26249245 1039279 3254915..3255067 1 NC_004431.1 hypothetical protein 3255067 1039279 c3410 Escherichia coli CFT073 hypothetical protein NP_755285.1 3254915 D 199310 CDS NP_755286.1 26249246 1039280 complement(3255077..3256420) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2817; Escherichia coli O157:H7 ortholog: z4134; N-acetylmuramoyl-L-alanine amidase 3256420 1039280 c3411 Escherichia coli CFT073 N-acetylmuramoyl-L-alanine amidase NP_755286.1 3255077 R 199310 CDS NP_755287.2 161486136 1039282 3256562..3257893 1 NC_004431.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3257893 argA 1039282 argA Escherichia coli CFT073 N-acetylglutamate synthase NP_755287.2 3256562 D 199310 CDS NP_755288.1 26249248 1039285 complement(3257955..3259781) 1 NC_004431.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3259781 recD 1039285 recD Escherichia coli CFT073 exonuclease V subunit alpha NP_755288.1 3257955 R 199310 CDS NP_755289.1 26249249 1039286 complement(3259781..3263332) 1 NC_004431.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3263332 recB 1039286 recB Escherichia coli CFT073 exonuclease V subunit beta NP_755289.1 3259781 R 199310 CDS NP_755290.1 26249250 1039287 complement(3263316..3266204) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2821; Escherichia coli O157:H7 ortholog: z4138; protease III 3266204 ptr 1039287 ptr Escherichia coli CFT073 protease III NP_755290.1 3263316 R 199310 CDS NP_755291.1 26249251 1039288 complement(3266380..3269748) 1 NC_004431.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3269748 recC 1039288 recC Escherichia coli CFT073 exonuclease V subunit gamma NP_755291.1 3266380 R 199310 CDS NP_755292.1 26249252 1039289 complement(3269761..3270084) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2823; Escherichia coli O157:H7 ortholog: z4140; hypothetical protein 3270084 ppdC 1039289 ppdC Escherichia coli CFT073 hypothetical protein NP_755292.1 3269761 R 199310 CDS NP_755293.1 26249253 1039291 complement(3270069..3270476) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2824; Escherichia coli O157:H7 ortholog: z4141; hypothetical protein 3270476 ygdB 1039291 ygdB Escherichia coli CFT073 hypothetical protein NP_755293.1 3270069 R 199310 CDS NP_755294.1 26249254 1039292 complement(3270473..3271060) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2825; Escherichia coli O157:H7 ortholog: z4142; hypothetical protein 3271060 ppdB 1039292 ppdB Escherichia coli CFT073 hypothetical protein NP_755294.1 3270473 R 199310 CDS NP_755295.1 26249255 1039293 complement(3271027..3271497) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2826; Escherichia coli O157:H7 ortholog: z4143; hypothetical protein 3271497 ppdA 1039293 ppdA Escherichia coli CFT073 hypothetical protein NP_755295.1 3271027 R 199310 CDS YP_004853818.1 347357937 1039294 3271486..3271689 1 NC_004431.1 hypothetical protein 3271689 1039294 c3421 Escherichia coli CFT073 hypothetical protein YP_004853818.1 3271486 D 199310 CDS NP_755297.1 26249257 1039295 complement(3271682..3272476) 1 NC_004431.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3272476 thyA 1039295 thyA Escherichia coli CFT073 thymidylate synthase NP_755297.1 3271682 R 199310 CDS NP_755298.1 26249258 1039296 complement(3272483..3273358) 1 NC_004431.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3273358 lgt 1039296 lgt Escherichia coli CFT073 prolipoprotein diacylglyceryl transferase NP_755298.1 3272483 R 199310 CDS NP_755299.1 26249259 1039297 complement(3273509..3275755) 1 NC_004431.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 3275755 ptsP 1039297 ptsP Escherichia coli CFT073 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain NP_755299.1 3273509 R 199310 CDS NP_755300.1 26249260 1039298 complement(3275768..3276298) 1 NC_004431.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3276298 ygdP 1039298 ygdP Escherichia coli CFT073 dinucleoside polyphosphate hydrolase NP_755300.1 3275768 R 199310 CDS NP_755301.1 26249261 1039299 3276983..3277672 1 NC_004431.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3277672 mutH 1039299 mutH Escherichia coli CFT073 DNA mismatch repair protein NP_755301.1 3276983 D 199310 CDS NP_755302.1 26249262 1039301 3277741..3278454 1 NC_004431.1 Escherichia coli K-12 ortholog: b2832; Escherichia coli O157:H7 ortholog: z4150; hypothetical protein 3278454 1039301 c3427 Escherichia coli CFT073 hypothetical protein NP_755302.1 3277741 D 199310 CDS NP_755303.1 26249263 1039302 3278592..3278810 1 NC_004431.1 Escherichia coli K-12 ortholog: b2833; Escherichia coli O157:H7 ortholog: z4151; lipoprotein ygdR 3278810 ygdR 1039302 ygdR Escherichia coli CFT073 lipoprotein ygdR NP_755303.1 3278592 D 199310 CDS NP_755304.1 26249264 1039303 3278918..3279958 1 NC_004431.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3279958 tas 1039303 tas Escherichia coli CFT073 aldo-keto reductase NP_755304.1 3278918 D 199310 CDS NP_755305.1 26249265 1039304 complement(3279990..3281183) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2835; Escherichia coli O157:H7 ortholog: z4153; lysophospholipid transporter LplT 3281183 ygeD 1039304 ygeD Escherichia coli CFT073 lysophospholipid transporter LplT NP_755305.1 3279990 R 199310 CDS NP_755306.1 26249266 1039306 complement(3281176..3283335) 1 NC_004431.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3283335 aas 1039306 aas Escherichia coli CFT073 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase NP_755306.1 3281176 R 199310 CDS NP_755307.1 26249267 1039308 complement(3283735..3284073) 1 NC_004431.1 Residues 1 to 112 of 112 are 96.42 pct identical to residues 41 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 3284073 1039308 c3432 Escherichia coli CFT073 transposase NP_755307.1 3283735 R 199310 CDS NP_755308.1 26249268 1039310 3284085..3284552 1 NC_004431.1 hypothetical protein 3284552 1039310 c3433 Escherichia coli CFT073 hypothetical protein NP_755308.1 3284085 D 199310 CDS NP_755309.1 26249269 1039311 3284632..3285663 1 NC_004431.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3285663 galR 1039311 galR Escherichia coli CFT073 DNA-binding transcriptional regulator GalR NP_755309.1 3284632 D 199310 CDS NP_755310.1 26249270 1039312 complement(3285670..3286932) 1 NC_004431.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3286932 lysA 1039312 lysA Escherichia coli CFT073 diaminopimelate decarboxylase NP_755310.1 3285670 R 199310 CDS NP_755311.1 26249271 1039313 3287054..3287989 1 NC_004431.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3287989 lysR 1039313 lysR Escherichia coli CFT073 LysR family transcriptional regulator NP_755311.1 3287054 D 199310 CDS NP_755312.1 26249272 1039314 complement(3287976..3288668) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2840; Escherichia coli O157:H7 ortholog: z4160; racemase 3288668 ygeA 1039314 ygeA Escherichia coli CFT073 racemase NP_755312.1 3287976 R 199310 CDS NP_755313.1 26249273 1039315 complement(3288797..3290344) 1 NC_004431.1 Arabinose transporter; Escherichia coli K-12 ortholog: b2841; Escherichia coli O157:H7 ortholog: z4161; arabinose-proton symporter 3290344 araE 1039315 araE Escherichia coli CFT073 arabinose-proton symporter NP_755313.1 3288797 R 199310 CDS NP_755314.1 26249274 1039316 complement(3290530..3291291) 1 NC_004431.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3291291 kduD 1039316 kduD Escherichia coli CFT073 2-deoxy-D-gluconate 3-dehydrogenase NP_755314.1 3290530 R 199310 CDS NP_755315.1 26249275 1039317 complement(3291321..3292157) 1 NC_004431.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3292157 kduI 1039317 kduI Escherichia coli CFT073 5-keto-4-deoxyuronate isomerase NP_755315.1 3291321 R 199310 CDS NP_755316.2 161486135 1039318 complement(3292444..3293625) 1 NC_004431.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3293625 yqeF 1039318 yqeF Escherichia coli CFT073 acetyl-CoA acetyltransferase NP_755316.2 3292444 R 199310 CDS NP_755317.1 26249277 1039319 3293880..3295109 1 NC_004431.1 Escherichia coli K-12 ortholog: b2845; Escherichia coli O157:H7 ortholog: z4165; transport protein YqeG 3295109 yqeG 1039319 yqeG Escherichia coli CFT073 transport protein YqeG NP_755317.1 3293880 D 199310 CDS NP_755318.1 26249278 1039323 complement(3295578..3296357) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2865; Escherichia coli O157:H7 ortholog: z4203; lipoprotein ygeR 3296357 ygeR 1039323 ygeR Escherichia coli CFT073 lipoprotein ygeR NP_755318.1 3295578 R 199310 CDS NP_755319.1 26249279 1039325 3296747..3299044 1 NC_004431.1 molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3299044 1039325 c3444 Escherichia coli CFT073 xanthine dehydrogenase subunit XdhA NP_755319.1 3296747 D 199310 CDS NP_755320.1 26249280 1039327 3299055..3299933 1 NC_004431.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3299933 ygeT 1039327 ygeT Escherichia coli CFT073 xanthine dehydrogenase subunit XdhB NP_755320.1 3299055 D 199310 CDS NP_755321.1 26249281 1039328 3299930..3300409 1 NC_004431.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3300409 1039328 c3446 Escherichia coli CFT073 xanthine dehydrogenase subunit XdhC NP_755321.1 3299930 D 199310 CDS NP_755322.1 26249282 1039329 complement(3300449..3302227) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2869; Escherichia coli O157:H7 ortholog: z4208; sigma-54-dependent transcriptional regulator ygeV 3302227 ygeV 1039329 ygeV Escherichia coli CFT073 sigma-54-dependent transcriptional regulator ygeV NP_755322.1 3300449 R 199310 CDS NP_755323.1 26249283 1039330 3302703..3303893 1 NC_004431.1 catalyzes the formation of L-citruline from L-ornithine and carbamoylphosphate; aspartate/ornithine carbamoyltransferase 3303893 ygeW 1039330 ygeW Escherichia coli CFT073 aspartate/ornithine carbamoyltransferase NP_755323.1 3302703 D 199310 CDS NP_755324.1 26249284 1039332 3303951..3305147 1 NC_004431.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3305147 ygeX 1039332 ygeX Escherichia coli CFT073 diaminopropionate ammonia-lyase NP_755324.1 3303951 D 199310 CDS NP_755325.1 26249285 1039333 3305205..3306416 1 NC_004431.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3306416 ygeY 1039333 ygeY Escherichia coli CFT073 peptidase NP_755325.1 3305205 D 199310 CDS NP_755326.2 161486134 1039334 3306470..3307855 1 NC_004431.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3307855 ygeZ 1039334 ygeZ Escherichia coli CFT073 phenylhydantoinase NP_755326.2 3306470 D 199310 CDS NP_755327.1 26249287 1039335 3307903..3308835 1 NC_004431.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3308835 yqeA 1039335 yqeA Escherichia coli CFT073 carbamate kinase NP_755327.1 3307903 D 199310 CDS NP_755328.1 26249288 1039336 complement(3308876..3310501) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2875; Escherichia coli O157:H7 ortholog: z4214; hypothetical protein 3310501 yqeB 1039336 yqeB Escherichia coli CFT073 hypothetical protein NP_755328.1 3308876 R 199310 CDS NP_755329.1 26249289 1039339 complement(3310549..3311319) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2876; Escherichia coli O157:H7 ortholog: z4215; hypothetical protein 3311319 yqeC 1039339 yqeC Escherichia coli CFT073 hypothetical protein NP_755329.1 3310549 R 199310 CDS NP_755330.1 26249290 1039340 3311423..3312001 1 NC_004431.1 Escherichia coli K-12 ortholog: b2877; Escherichia coli O157:H7 ortholog: z4216; hypothetical protein 3312001 ygfJ 1039340 ygfJ Escherichia coli CFT073 hypothetical protein NP_755330.1 3311423 D 199310 CDS NP_755331.1 26249291 1039341 3312323..3315421 1 NC_004431.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3315421 ygfK 1039341 ygfK Escherichia coli CFT073 selenate reductase subunit YgfK NP_755331.1 3312323 D 199310 CDS NP_755332.2 161486133 1039342 3315424..3316752 1 NC_004431.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3316752 1039342 c3457 Escherichia coli CFT073 chlorohydrolase/aminohydrolase NP_755332.2 3315424 D 199310 CDS NP_755333.1 26249293 1039345 3316803..3317582 1 NC_004431.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3317582 ygfM 1039345 ygfM Escherichia coli CFT073 selenate reductase subunit YgfM NP_755333.1 3316803 D 199310 CDS NP_755334.1 26249294 1039347 3317579..3320449 1 NC_004431.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3320449 1039347 c3459 Escherichia coli CFT073 selenate reductase subunit YgfN NP_755334.1 3317579 D 199310 CDS NP_755335.1 26249295 1039348 3320557..3322014 1 NC_004431.1 Escherichia coli K-12 ortholog: b2882; Escherichia coli O157:H7 ortholog: z4221; purine permease ygfO 3322014 ygfO 1039348 ygfO Escherichia coli CFT073 purine permease ygfO NP_755335.1 3320557 D 199310 CDS NP_755336.1 26249296 1039349 3321909..3323348 1 NC_004431.1 Catalyzes the deamination of guanine; guanine deaminase 3323348 ygfP 1039349 ygfP Escherichia coli CFT073 guanine deaminase NP_755336.1 3321909 D 199310 CDS NP_755337.1 26249297 1039350 3323384..3324751 1 NC_004431.1 Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z4223; hypothetical protein 3324751 1039350 c3462 Escherichia coli CFT073 hypothetical protein NP_755337.1 3323384 D 199310 CDS NP_755338.1 26249298 1039351 complement(3324787..3325278) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2886; Escherichia coli O157:H7 ortholog: z4224; electron transport protein ygfS 3325278 ygfS 1039351 ygfS Escherichia coli CFT073 electron transport protein ygfS NP_755338.1 3324787 R 199310 CDS NP_755339.1 26249299 1039353 complement(3325275..3327209) 1 NC_004431.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 3327209 ygfT 1039353 ygfT Escherichia coli CFT073 oxidoreductase Fe-S binding subunit NP_755339.1 3325275 R 199310 CDS NP_755340.1 26249300 1039354 3327501..3329078 1 NC_004431.1 Escherichia coli K-12 ortholog: b2888; Escherichia coli O157:H7 ortholog: z4226; purine permease ygfU 3329078 ygfU 1039354 ygfU Escherichia coli CFT073 purine permease ygfU NP_755340.1 3327501 D 199310 CDS NP_755341.1 26249301 1039355 3329062..3329205 1 NC_004431.1 hypothetical protein 3329205 1039355 c3466 Escherichia coli CFT073 hypothetical protein NP_755341.1 3329062 D 199310 CDS NP_755342.1 26249302 1039356 3329328..3329876 1 NC_004431.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3329876 1039356 c3467 Escherichia coli CFT073 isopentenyl-diphosphate delta-isomerase NP_755342.1 3329328 D 199310 CDS NP_755343.1 26249303 1039359 complement(3329981..3330490) 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 3330490 1039359 c3468 Escherichia coli CFT073 hypothetical protein NP_755343.1 3329981 R 199310 CDS NP_755344.1 26249304 1039360 complement(3330630..3332147) 1 NC_004431.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3332147 lysS 1039360 lysS Escherichia coli CFT073 lysyl-tRNA synthetase NP_755344.1 3330630 R 199310 CDS NP_755345.1 26249305 1039361 3330747..3332162 1 NC_004431.1 hypothetical protein 3332162 1039361 c3470 Escherichia coli CFT073 hypothetical protein NP_755345.1 3330747 D 199310 CDS NP_755346.1 26249306 1039362 complement(join(3332157..3333179,3333181..3333255)) 1 NC_004431.1 RF-2; recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 3333255 prfB 1039362 prfB Escherichia coli CFT073 peptide chain release factor 2 NP_755346.1 3332157 R 199310 CDS NP_755347.1 26249307 1039363 complement(3333346..3335079) 1 NC_004431.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3335079 recJ 1039363 recJ Escherichia coli CFT073 ssDNA exonuclease RecJ NP_755347.1 3333346 R 199310 CDS NP_755348.1 26249308 1039364 complement(3335085..3335795) 1 NC_004431.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3335795 dsbC 1039364 dsbC Escherichia coli CFT073 thiol:disulfide interchange protein DsbC NP_755348.1 3335085 R 199310 CDS NP_755349.1 26249309 1039365 complement(3335820..3336716) 1 NC_004431.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3336716 xerD 1039365 xerD Escherichia coli CFT073 site-specific tyrosine recombinase XerD NP_755349.1 3335820 R 199310 CDS NP_755350.1 26249310 1039367 3336828..3337349 1 NC_004431.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3337349 fldB 1039367 fldB Escherichia coli CFT073 flavodoxin FldB NP_755350.1 3336828 D 199310 CDS NP_755351.1 26249311 1039368 complement(3337389..3337796) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2896; Escherichia coli O157:H7 ortholog: z4234; hypothetical protein 3337796 ygfX 1039368 ygfX Escherichia coli CFT073 hypothetical protein NP_755351.1 3337389 R 199310 CDS NP_755352.1 26249312 1039369 complement(3337777..3338043) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2897; Escherichia coli O157:H7 ortholog: z4235; hypothetical protein 3338043 ygfY 1039369 ygfY Escherichia coli CFT073 hypothetical protein NP_755352.1 3337777 R 199310 CDS NP_755353.1 26249313 1039371 3338018..3338209 1 NC_004431.1 hypothetical protein 3338209 1039371 c3478 Escherichia coli CFT073 hypothetical protein NP_755353.1 3338018 D 199310 CDS NP_755354.1 26249314 1039372 3338286..3339266 1 NC_004431.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3339266 ygfZ 1039372 ygfZ Escherichia coli CFT073 global regulator NP_755354.1 3338286 D 199310 CDS NP_755355.1 26249315 1039374 complement(3339343..3340002) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2899; Escherichia coli O157:H7 ortholog: z4237; hypothetical protein 3340002 yqfA 1039374 yqfA Escherichia coli CFT073 hypothetical protein NP_755355.1 3339343 R 199310 CDS NP_755356.1 26249316 1039375 complement(3340166..3340477) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2900; Escherichia coli O157:H7 ortholog: z4238; hypothetical protein 3340477 yqfB 1039375 yqfB Escherichia coli CFT073 hypothetical protein NP_755356.1 3340166 R 199310 CDS NP_755357.1 26249317 1039376 3340498..3341955 1 NC_004431.1 Escherichia coli K-12 ortholog: b2901; Escherichia coli O157:H7 ortholog: z4239; 6-phospho-beta-glucosidase 3341955 bglA 1039376 bglA Escherichia coli CFT073 6-phospho-beta-glucosidase NP_755357.1 3340498 D 199310 CDS NP_755358.1 26249318 1039377 complement(3342121..3344994) 1 NC_004431.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3344994 gcvP 1039377 gcvP Escherichia coli CFT073 glycine dehydrogenase NP_755358.1 3342121 R 199310 CDS NP_755359.1 26249319 1039378 complement(3345112..3345504) 1 NC_004431.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3345504 gcvH 1039378 gcvH Escherichia coli CFT073 glycine cleavage system protein H NP_755359.1 3345112 R 199310 CDS NP_755360.1 26249320 1039380 complement(3345525..3346619) 1 NC_004431.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3346619 gcvT 1039380 gcvT Escherichia coli CFT073 glycine cleavage system aminomethyltransferase T NP_755360.1 3345525 R 199310 CDS NP_755361.1 26249321 1039381 complement(3346627..3346782) 1 NC_004431.1 hypothetical protein 3346782 1039381 c3486 Escherichia coli CFT073 hypothetical protein NP_755361.1 3346627 R 199310 CDS NP_755362.1 26249322 1039382 complement(3346795..3346944) 1 NC_004431.1 hypothetical protein 3346944 1039382 c3487 Escherichia coli CFT073 hypothetical protein NP_755362.1 3346795 R 199310 CDS NP_755363.1 26249323 1039383 complement(3347067..3348269) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2906; Escherichia coli O157:H7 ortholog: z4243; hypothetical protein 3348269 visC 1039383 visC Escherichia coli CFT073 hypothetical protein NP_755363.1 3347067 R 199310 CDS NP_755364.1 26249324 1039384 complement(3348292..3349470) 1 NC_004431.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3349470 ubiH 1039384 ubiH Escherichia coli CFT073 2-octaprenyl-6-methoxyphenyl hydroxylase NP_755364.1 3348292 R 199310 CDS NP_755365.1 26249325 1039385 complement(3349467..3350792) 1 NC_004431.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3350792 pepP 1039385 pepP Escherichia coli CFT073 proline aminopeptidase P II NP_755365.1 3349467 R 199310 CDS NP_755366.2 161486132 1039386 complement(3350818..3351396) 1 NC_004431.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3351396 ygfB 1039386 ygfB Escherichia coli CFT073 hypothetical protein NP_755366.2 3350818 R 199310 CDS NP_755367.1 26249327 1039387 3351564..3351893 1 NC_004431.1 Escherichia coli K-12 ortholog: b2910; Escherichia coli O157:H7 ortholog: z4247; Z-ring-associated protein 3351893 ygfE 1039387 ygfE Escherichia coli CFT073 Z-ring-associated protein NP_755367.1 3351564 D 199310 CDS NP_755368.2 229106372 1039389 3352193..3352741 1 NC_004431.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3352741 ygfA 1039389 ygfA Escherichia coli CFT073 ligase NP_755368.2 3352193 D 199310 CDS NP_755369.1 26249329 1039390 complement(3353131..3354363) 1 NC_004431.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3354363 serA 1039390 serA Escherichia coli CFT073 D-3-phosphoglycerate dehydrogenase NP_755369.1 3353131 R 199310 CDS NP_755370.1 26249330 1039391 complement(3354619..3355350) 1 NC_004431.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3355350 rpiA 1039391 rpiA Escherichia coli CFT073 ribose-5-phosphate isomerase A NP_755370.1 3354619 R 199310 CDS NP_755371.1 26249331 1039392 complement(3355334..3355612) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2915; hypothetical protein 3355612 yqfE 1039392 yqfE Escherichia coli CFT073 hypothetical protein NP_755371.1 3355334 R 199310 CDS NP_755372.2 161486131 1039393 3355705..3356598 1 NC_004431.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3356598 iciA 1039393 iciA Escherichia coli CFT073 chromosome replication initiation inhibitor protein NP_755372.2 3355705 D 199310 CDS NP_755373.1 26249333 1039394 3356801..3357856 1 NC_004431.1 Residues 1 to 309 of 351 are 86.88 pct identical to residues 1 to 343 of 714 from MG1655 : b2917; hypothetical protein 3357856 1039394 c3498 Escherichia coli CFT073 hypothetical protein NP_755373.1 3356801 D 199310 CDS NP_755374.1 26249334 1039395 complement(3357853..3358749) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2921; Escherichia coli O157:H7 ortholog: z4258; transcriptional regulator YgfI 3358749 ygfI 1039395 ygfI Escherichia coli CFT073 transcriptional regulator YgfI NP_755374.1 3357853 R 199310 CDS NP_755375.1 26249335 1039396 complement(3358907..3359647) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2922; Escherichia coli O157:H7 ortholog: z4259; hypothetical protein 3359647 yggE 1039396 yggE Escherichia coli CFT073 hypothetical protein NP_755375.1 3358907 R 199310 CDS NP_755376.1 26249336 1039397 complement(3359740..3360375) 1 NC_004431.1 Involved in the export of arginine; arginine exporter protein 3360375 yggA 1039397 yggA Escherichia coli CFT073 arginine exporter protein NP_755376.1 3359740 R 199310 CDS NP_755377.1 26249337 1039400 complement(3360514..3361374) 1 NC_004431.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3361374 yggB 1039400 yggB Escherichia coli CFT073 mechanosensitive channel MscS NP_755377.1 3360514 R 199310 CDS NP_755378.2 161486130 1039401 complement(3361565..3362644) 1 NC_004431.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3362644 fba 1039401 fba Escherichia coli CFT073 fructose-bisphosphate aldolase NP_755378.2 3361565 R 199310 CDS NP_755379.1 26249339 1039404 complement(3362858..3364084) 1 NC_004431.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3364084 pgk 1039404 pgk Escherichia coli CFT073 phosphoglycerate kinase NP_755379.1 3362858 R 199310 CDS NP_755380.2 161486129 1039405 complement(3364071..3365090) 1 NC_004431.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3365090 epd 1039405 epd Escherichia coli CFT073 erythrose 4-phosphate dehydrogenase NP_755380.2 3364071 R 199310 CDS NP_755381.1 26249341 1039406 3365462..3365890 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4267; hypothetical protein 3365890 1039406 c3506 Escherichia coli CFT073 hypothetical protein NP_755381.1 3365462 D 199310 CDS NP_755382.1 26249342 1039407 3365917..3366495 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4268; hypothetical protein 3366495 1039407 c3507 Escherichia coli CFT073 hypothetical protein NP_755382.1 3365917 D 199310 CDS NP_755383.1 26249343 1039408 3366496..3367203 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4269; hypothetical protein 3367203 1039408 c3508 Escherichia coli CFT073 hypothetical protein NP_755383.1 3366496 D 199310 CDS NP_755384.1 26249344 1039409 3367332..3367868 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4270; ABC transporter ATP-binding protein 3367868 1039409 c3509 Escherichia coli CFT073 ABC transporter ATP-binding protein NP_755384.1 3367332 D 199310 CDS NP_755385.1 26249345 1039410 3367829..3368539 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4271; ABC transporter ATP-binding protein 3368539 1039410 c3510 Escherichia coli CFT073 ABC transporter ATP-binding protein NP_755385.1 3367829 D 199310 CDS NP_755386.1 26249346 1039411 complement(3368511..3369224) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2928; Escherichia coli O157:H7 ortholog: z4273; fructose transport system kinase 3369224 frcK 1039411 frcK Escherichia coli CFT073 fructose transport system kinase NP_755386.1 3368511 R 199310 CDS NP_755387.1 26249347 1039417 complement(3369221..3369730) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2929; Escherichia coli O157:H7 ortholog: z4274; DNA-binding transcriptional regulator 3369730 yggD 1039417 yggD Escherichia coli CFT073 DNA-binding transcriptional regulator NP_755387.1 3369221 R 199310 CDS NP_755388.1 26249348 1039419 complement(3369879..3370067) 1 NC_004431.1 Residues 1 to 58 of 62 are 100.00 pct identical to residues 1 to 58 of 321 from MG1655 : b2930; hypothetical protein 3370067 1039419 c3513 Escherichia coli CFT073 hypothetical protein NP_755388.1 3369879 R 199310 CDS NP_755389.1 26249349 1039420 complement(3370064..3371341) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z4276; oxidoreductase 3371341 1039420 c3514 Escherichia coli CFT073 oxidoreductase NP_755389.1 3370064 R 199310 CDS NP_755390.1 26249350 1039421 complement(3371356..3372744) 1 NC_004431.1 EIIBC-(C)MTL; Escherichia coli K-12 ortholog: b2933; Escherichia coli O157:H7 ortholog: z4277; PTS system, mannitol (Cryptic)-specific IIBC component 3372744 cmtA 1039421 cmtA Escherichia coli CFT073 PTS system, mannitol (Cryptic)-specific IIBC component NP_755390.1 3371356 R 199310 CDS NP_755391.1 26249351 1039424 complement(3372772..3373215) 1 NC_004431.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 3373215 cmtB 1039424 cmtB Escherichia coli CFT073 mannitol phosphotransferase subunit EIIA NP_755391.1 3372772 R 199310 CDS NP_755392.1 26249352 1039426 3373532..3374266 1 NC_004431.1 Residues 38 to 224 of 244 are 48.93 pct identical to residues 18 to 205 of 308 from GenPept.129 : >emb|CAC90171.1| (AJ414147) SPFH domain protein [Yersinia pestis]; hypothetical protein 3374266 1039426 c3517 Escherichia coli CFT073 hypothetical protein NP_755392.1 3373532 D 199310 CDS YP_004853819.1 347357914 1039427 complement(3374240..3374698) 1 NC_004431.1 hypothetical protein 3374698 1039427 c3518 Escherichia coli CFT073 hypothetical protein YP_004853819.1 3374240 R 199310 CDS YP_004853820.1 347357915 1039429 complement(3374337..3374705) 1 NC_004431.1 hypothetical protein 3374705 1039429 c3519 Escherichia coli CFT073 hypothetical protein YP_004853820.1 3374337 R 199310 CDS NP_755395.2 161486128 1039430 complement(3374714..3376705) 1 NC_004431.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3376705 tktA 1039430 tktA Escherichia coli CFT073 transketolase NP_755395.2 3374714 R 199310 CDS NP_755396.1 26249356 1039431 3376764..3377741 1 NC_004431.1 Escherichia coli K-12 ortholog: b2936; Escherichia coli O157:H7 ortholog: z4280; metalloprotease yggG 3377741 yggG 1039431 yggG Escherichia coli CFT073 metalloprotease yggG NP_755396.1 3376764 D 199310 CDS NP_755397.1 26249357 1039433 complement(3377945..3378865) 1 NC_004431.1 catalyzes the formation of putrescine from agmatine; agmatinase 3378865 speB 1039433 speB Escherichia coli CFT073 agmatinase NP_755397.1 3377945 R 199310 CDS NP_755398.1 26249358 1039435 complement(3379001..3379732) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4282; hypothetical protein 3379732 1039435 c3523 Escherichia coli CFT073 hypothetical protein NP_755398.1 3379001 R 199310 CDS NP_755399.1 26249359 1039437 complement(3379878..3381866) 1 NC_004431.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3381866 speA 1039437 speA Escherichia coli CFT073 arginine decarboxylase NP_755399.1 3379878 R 199310 CDS NP_755400.1 26249360 1039438 complement(3381863..3382009) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2939; Escherichia coli O157:H7 ortholog: z4284; hypothetical protein 3382009 yqgB 1039438 yqgB Escherichia coli CFT073 hypothetical protein NP_755400.1 3381863 R 199310 CDS NP_755401.1 26249361 1039439 3382329..3382454 1 NC_004431.1 hypothetical protein 3382454 1039439 c3526 Escherichia coli CFT073 hypothetical protein NP_755401.1 3382329 D 199310 CDS NP_755402.1 26249362 1039440 complement(3382342..3382608) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2941; Escherichia coli O157:H7 ortholog: z4286; hypothetical protein 3382608 yqgD 1039440 yqgD Escherichia coli CFT073 hypothetical protein NP_755402.1 3382342 R 199310 CDS NP_755403.2 161486127 1039441 3382649..3383803 1 NC_004431.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3383803 metK 1039441 metK Escherichia coli CFT073 S-adenosylmethionine synthetase NP_755403.2 3382649 D 199310 CDS NP_755404.1 26249364 1039442 3384227..3385633 1 NC_004431.1 Galactose transporter; Escherichia coli K-12 ortholog: b2943; Escherichia coli O157:H7 ortholog: z4288; galactose-proton symporter 3385633 galP 1039442 galP Escherichia coli CFT073 galactose-proton symporter NP_755404.1 3384227 D 199310 CDS NP_755405.1 26249365 1039443 3385656..3386207 1 NC_004431.1 Escherichia coli K-12 ortholog: b2944; Escherichia coli O157:H7 ortholog: z4289; hypothetical protein 3386207 sprT 1039443 sprT Escherichia coli CFT073 hypothetical protein NP_755405.1 3385656 D 199310 CDS NP_755406.1 26249366 1039444 3386299..3387009 1 NC_004431.1 Escherichia coli K-12 ortholog: b2945; Escherichia coli O157:H7 ortholog: z4290; endonuclease I 3387009 endA 1039444 endA Escherichia coli CFT073 endonuclease I NP_755406.1 3386299 D 199310 CDS NP_755407.2 161486126 1039445 3387089..3387820 1 NC_004431.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3387820 yggJ 1039445 yggJ Escherichia coli CFT073 16S ribosomal RNA methyltransferase RsmE NP_755407.2 3387089 D 199310 CDS NP_755408.1 26249368 1039448 3387833..3388783 1 NC_004431.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3388783 gshB 1039448 gshB Escherichia coli CFT073 glutathione synthetase NP_755408.1 3387833 D 199310 CDS NP_755409.2 161486125 1039449 3388892..3389455 1 NC_004431.1 Escherichia coli K-12 ortholog: b2948; Escherichia coli O157:H7 ortholog: z4293; hypothetical protein 3389455 yqgE 1039449 yqgE Escherichia coli CFT073 hypothetical protein NP_755409.2 3388892 D 199310 CDS NP_755410.1 26249370 1039450 3389455..3389871 1 NC_004431.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3389871 yqgF 1039450 yqgF Escherichia coli CFT073 Holliday junction resolvase-like protein NP_755410.1 3389455 D 199310 CDS NP_755411.1 26249371 1039451 complement(3390045..3391100) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295; hypothetical protein 3391100 yggR 1039451 yggR Escherichia coli CFT073 hypothetical protein NP_755411.1 3390045 R 199310 CDS NP_755412.1 26249372 1039453 3391043..3391747 1 NC_004431.1 Escherichia coli K-12 ortholog: b2951; Escherichia coli O157:H7 ortholog: z4296; hypothetical protein 3391747 yggS 1039453 yggS Escherichia coli CFT073 hypothetical protein NP_755412.1 3391043 D 199310 CDS NP_755413.1 26249373 1039454 3391765..3392331 1 NC_004431.1 Escherichia coli K-12 ortholog: b2952; Escherichia coli O157:H7 ortholog: z4297; hypothetical protein 3392331 yggT 1039454 yggT Escherichia coli CFT073 hypothetical protein NP_755413.1 3391765 D 199310 CDS NP_755414.2 161486124 1039455 3392328..3392618 1 NC_004431.1 Escherichia coli K-12 ortholog: b2953; Escherichia coli O157:H7 ortholog: z4298; hypothetical protein 3392618 yggU 1039455 yggU Escherichia coli CFT073 hypothetical protein NP_755414.2 3392328 D 199310 CDS NP_755415.1 26249375 1039457 3392626..3393219 1 NC_004431.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3393219 yggV 1039457 yggV Escherichia coli CFT073 deoxyribonucleotide triphosphate pyrophosphatase NP_755415.1 3392626 D 199310 CDS NP_755416.1 26249376 1039458 3393212..3394348 1 NC_004431.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3394348 yggW 1039458 yggW Escherichia coli CFT073 coproporphyrinogen III oxidase NP_755416.1 3393212 D 199310 CDS NP_755417.1 26249377 1039459 complement(3394417..3395424) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2956; Escherichia coli O157:H7 ortholog: z4301; hypothetical protein 3395424 yggM 1039459 yggM Escherichia coli CFT073 hypothetical protein NP_755417.1 3394417 R 199310 CDS NP_755418.1 26249378 1039460 complement(3395541..3396587) 1 NC_004431.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3396587 ansB 1039460 ansB Escherichia coli CFT073 L-asparaginase II NP_755418.1 3395541 R 199310 CDS NP_755419.1 26249379 1039461 complement(3396763..3397482) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2958; Escherichia coli O157:H7 ortholog: z4303; hypothetical protein 3397482 yggN 1039461 yggN Escherichia coli CFT073 hypothetical protein NP_755419.1 3396763 R 199310 CDS NP_755420.1 26249380 1039462 complement(3397503..3397643) 1 NC_004431.1 hypothetical protein 3397643 1039462 c3545 Escherichia coli CFT073 hypothetical protein NP_755420.1 3397503 R 199310 CDS NP_755421.2 161486123 1039463 complement(3397666..3397992) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2959; Escherichia coli O157:H7 ortholog: z4304; hypothetical protein 3397992 yggL 1039463 yggL Escherichia coli CFT073 hypothetical protein NP_755421.2 3397666 R 199310 CDS NP_755422.1 26249382 1039465 complement(3397992..3398711) 1 NC_004431.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3398711 trmB 1039465 trmB Escherichia coli CFT073 tRNA (guanine-N(7)-)-methyltransferase NP_755422.1 3397992 R 199310 CDS NP_755423.1 26249383 1039467 3398842..3399924 1 NC_004431.1 Escherichia coli K-12 ortholog: b2961; Escherichia coli O157:H7 ortholog: z4306; adenine DNA glycosylase 3399924 mutY 1039467 mutY Escherichia coli CFT073 adenine DNA glycosylase NP_755423.1 3398842 D 199310 CDS NP_755424.1 26249384 1039468 complement(3399901..3400194) 1 NC_004431.1 hypothetical protein 3400194 1039468 c3549 Escherichia coli CFT073 hypothetical protein NP_755424.1 3399901 R 199310 CDS NP_755425.1 26249385 1039469 3399952..3400227 1 NC_004431.1 Escherichia coli K-12 ortholog: b2962; Escherichia coli O157:H7 ortholog: z4307; hypothetical protein 3400227 yggX 1039469 yggX Escherichia coli CFT073 hypothetical protein NP_755425.1 3399952 D 199310 CDS NP_755426.1 26249386 1039470 3400289..3401371 1 NC_004431.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3401371 mltC 1039470 mltC Escherichia coli CFT073 murein transglycosylase C NP_755426.1 3400289 D 199310 CDS NP_755427.1 26249387 1039472 3401525..3402829 1 NC_004431.1 Nucleoside-transport system protein nupG; Escherichia coli K-12 ortholog: b2964; Escherichia coli O157:H7 ortholog: z4309; nucleoside permease nupG 3402829 nupG 1039472 nupG Escherichia coli CFT073 nucleoside permease nupG NP_755427.1 3401525 D 199310 CDS NP_755428.1 26249388 1039473 complement(3402878..3405013) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2965; Escherichia coli O157:H7 ortholog: z4310; ornithine decarboxylase 3405013 speC 1039473 speC Escherichia coli CFT073 ornithine decarboxylase NP_755428.1 3402878 R 199310 CDS NP_755429.1 26249389 1039474 complement(3405094..3405297) 1 NC_004431.1 hypothetical protein 3405297 1039474 c3554 Escherichia coli CFT073 hypothetical protein NP_755429.1 3405094 R 199310 CDS NP_755430.1 26249390 1039475 3405412..3406119 1 NC_004431.1 Escherichia coli K-12 ortholog: b2966; Escherichia coli O157:H7 ortholog: z4311; hypothetical protein 3406119 yqgA 1039475 yqgA Escherichia coli CFT073 hypothetical protein NP_755430.1 3405412 D 199310 CDS NP_755431.1 26249391 1039478 3406498..3407763 1 NC_004431.1 Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 3407763 1039478 c3556 Escherichia coli CFT073 prophage P4 integrase NP_755431.1 3406498 D 199310 CDS NP_755432.1 26249392 1039480 3408019..3409062 1 NC_004431.1 Residues 1 to 347 of 347 are 83.28 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri]; ShiA-like protein 3409062 1039480 c3557 Escherichia coli CFT073 ShiA-like protein NP_755432.1 3408019 D 199310 CDS NP_755433.1 26249393 1039482 3409205..3409423 1 NC_004431.1 hypothetical protein 3409423 1039482 c3558 Escherichia coli CFT073 hypothetical protein NP_755433.1 3409205 D 199310 CDS NP_755434.1 26249394 1039483 complement(3409389..3410474) 1 NC_004431.1 Escherichia coli K-12 B4275 pseudogene; Residues 43 to 325 of 361 are 91.16 pct identical to residues 89 to 371 of 371 from SwissProt.40 : >sp|P39349|YJGX_ECOLI HYPOTHETICAL PROTEIN YJGX PRECURSOR; hypothetical protein 3410474 1039483 c3559 Escherichia coli CFT073 hypothetical protein NP_755434.1 3409389 R 199310 CDS NP_755435.1 26249395 1039484 3410473..3410877 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5096; hypothetical protein 3410877 1039484 c3560 Escherichia coli CFT073 hypothetical protein NP_755435.1 3410473 D 199310 CDS NP_755436.1 26249396 1039485 3410874..3411221 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4336; hypothetical protein 3411221 1039485 c3561 Escherichia coli CFT073 hypothetical protein NP_755436.1 3410874 D 199310 CDS NP_755437.1 26249397 1039486 3411270..3411677 1 NC_004431.1 Residues 1 to 135 of 135 are 83.70 pct identical to residues 1 to 135 of 461 from GenPept.129 : >gb|AAL08460.1|AF326777_35 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3411677 1039486 c3562 Escherichia coli CFT073 hypothetical protein NP_755437.1 3411270 D 199310 CDS NP_755438.1 26249398 1039487 3411690..3412808 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5098; hypothetical protein 3412808 1039487 c3563 Escherichia coli CFT073 hypothetical protein NP_755438.1 3411690 D 199310 CDS NP_755439.1 26249399 1039488 complement(3413218..3414690) 1 NC_004431.1 Residues 169 to 490 of 490 are 26.31 pct identical to residues 162 to 473 of 475 from GenPept.129 : >gb|AAK81155.1|AE007818_1 (AE007818) Membrane associated histidine kinase with HAMP domain [Clostridium acetobutylicum]; hypothetical protein 3414690 1039488 c3564 Escherichia coli CFT073 hypothetical protein NP_755439.1 3413218 R 199310 CDS NP_755440.1 26249400 1039491 complement(3414691..3415413) 1 NC_004431.1 Residues 6 to 232 of 240 are 47.16 pct identical to residues 12 to 240 of 247 from GenPept.129 : >gb|AAD36722.1|AE001807_13 (AE001807) response regulator DrrA [Thermotoga maritima]; response regulator 3415413 1039491 c3565 Escherichia coli CFT073 response regulator NP_755440.1 3414691 R 199310 CDS NP_755441.1 26249401 1039492 3415551..3415946 1 NC_004431.1 Residues 5 to 128 of 131 are 50.00 pct identical to residues 18 to 141 of 212 from GenPept.129 : >emb|CAD14149.1| (AL646060) TRANSMEMBRANE HYDROGENASE CYTOCHROME B-TYPE SUBUNIT OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]; hypothetical protein 3415946 1039492 c3566 Escherichia coli CFT073 hypothetical protein NP_755441.1 3415551 D 199310 CDS NP_755442.1 26249402 1039493 3416056..3416892 1 NC_004431.1 Residues 42 to 278 of 278 are 54.20 pct identical to residues 11 to 248 of 257 from GenPept.129 : >emb|CAD14150.1| (AL646060) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 3416892 1039493 c3567 Escherichia coli CFT073 hypothetical protein NP_755442.1 3416056 D 199310 CDS NP_755443.1 26249403 1039494 3416947..3417189 1 NC_004431.1 hypothetical protein 3417189 1039494 c3568 Escherichia coli CFT073 hypothetical protein NP_755443.1 3416947 D 199310 CDS NP_755444.1 26249404 1039495 3418210..3418884 1 NC_004431.1 Residues 55 to 224 of 224 are 97.64 pct identical to residues 1 to 170 of 170 from SwissProt.40 : >sp|P09984|HLC1_ECOLI HEMOLYSIN-ACTIVATING LYSINE-ACYLTRANSFERASE HLYC (TOXIN-ACTIVATING PROTEIN C, J96) (HEMOLYSIN C); hemolysin C 3418884 hlyC 1039495 hlyC Escherichia coli CFT073 hemolysin C NP_755444.1 3418210 D 199310 CDS NP_755445.1 26249405 1039496 3418896..3421970 1 NC_004431.1 Residues 1 to 1024 of 1024 are 98.63 pct identical to residues 1 to 1023 of 1023 from SwissProt.40 : >sp|P09983|HLY1_ECOLI HEMOLYSIN, CHROMOSOMAL; hemolysin A 3421970 hlyA 1039496 hlyA Escherichia coli CFT073 hemolysin A NP_755445.1 3418896 D 199310 CDS NP_755446.1 26249406 1039498 complement(3421458..3421610) 1 NC_004431.1 hypothetical protein 3421610 1039498 c3571 Escherichia coli CFT073 hypothetical protein NP_755446.1 3421458 R 199310 CDS NP_755447.1 26249407 1039500 complement(3421802..3422014) 1 NC_004431.1 hypothetical protein 3422014 1039500 c3572 Escherichia coli CFT073 hypothetical protein NP_755447.1 3421802 R 199310 CDS NP_755448.1 26249408 1039501 3422041..3424164 1 NC_004431.1 Residues 1 to 707 of 707 are 99.57 pct identical to residues 1 to 707 of 707 from SwissProt.40 : >sp|P10089|HLY2_ECOLI Hemolysin secretion ATP-binding protein, chromosomal; hemolysin B 3424164 hlyB 1039501 hlyB Escherichia coli CFT073 hemolysin B NP_755448.1 3422041 D 199310 CDS NP_755449.1 26249409 1039502 3424183..3425619 1 NC_004431.1 Residues 1 to 478 of 478 are 98.95 pct identical to residues 1 to 478 of 478 from SwissProt.40 : >sp|P09986|HLY4_ECOLI Hemolysin secretion protein D, chromosomal; hemolysin D 3425619 hlyD 1039502 hlyD Escherichia coli CFT073 hemolysin D NP_755449.1 3424183 D 199310 CDS NP_755450.1 26249410 1039504 complement(3425931..3426749) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2089; Escherichia coli O157:H7 ortholog: z1573; transposase insF 3426749 1039504 c3575 Escherichia coli CFT073 transposase insF NP_755450.1 3425931 R 199310 CDS NP_755451.1 26249411 1039510 complement(3426785..3427087) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1589; hypothetical protein 3427087 1039510 c3576 Escherichia coli CFT073 hypothetical protein NP_755451.1 3426785 R 199310 CDS NP_755452.1 26249412 1039511 3427169..3427570 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5096; hypothetical protein 3427570 1039511 c3577 Escherichia coli CFT073 hypothetical protein NP_755452.1 3427169 D 199310 CDS NP_755453.1 26249413 1039512 3427567..3427914 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5097; hypothetical protein 3427914 1039512 c3578 Escherichia coli CFT073 hypothetical protein NP_755453.1 3427567 D 199310 CDS NP_755454.1 26249414 1039513 complement(3427962..3428432) 1 NC_004431.1 Residues 118 to 151 of 156 are 97.05 pct identical to residues 36 to 69 of 95 from GenPept.129 : >emb|CAC81894.1| (AJ277443) ST56 protein [Escherichia coli]; hypothetical protein 3428432 1039513 c3579 Escherichia coli CFT073 hypothetical protein NP_755454.1 3427962 R 199310 CDS NP_755455.1 26249415 1039514 3427964..3428356 1 NC_004431.1 Residues 1 to 108 of 130 are 100.00 pct identical to residues 1 to 108 of 461 from GenPept.129 : >gb|AAL08460.1|AF326777_35 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3428356 1039514 c3580 Escherichia coli CFT073 hypothetical protein NP_755455.1 3427964 D 199310 CDS NP_755456.1 26249416 1039515 complement(3428529..3428678) 1 NC_004431.1 hypothetical protein 3428678 1039515 c3581 Escherichia coli CFT073 hypothetical protein NP_755456.1 3428529 R 199310 CDS NP_755457.1 26249417 1039516 complement(3428779..3429330) 1 NC_004431.1 Residues 18 to 183 of 183 are 96.38 pct identical to residues 1 to 166 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; PapX protein 3429330 papX 1039516 papX Escherichia coli CFT073 PapX protein NP_755457.1 3428779 R 199310 CDS NP_755458.1 26249418 1039518 complement(3429593..3430603) 1 NC_004431.1 Residues 1 to 336 of 336 are 57.01 pct identical to residues 1 to 335 of 335 from SwissProt.40 : >sp|P42188|PRSG_ECOLI FIMBRIAL PROTEIN PRSG PRECURSOR (ADHESIN); PapG protein 3430603 papG 1039518 papG Escherichia coli CFT073 PapG protein NP_755458.1 3429593 R 199310 CDS NP_755459.1 26249419 1039519 complement(3430647..3431177) 1 NC_004431.1 Residues 11 to 176 of 176 are 92.81 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P42187|PRSF_ECOLI MINOR FIMBRIAL PROTEIN PRSF PRECURSOR; PapF protein 3431177 papF 1039519 papF Escherichia coli CFT073 PapF protein NP_755459.1 3430647 R 199310 CDS NP_755460.1 26249420 1039520 complement(3431222..3431761) 1 NC_004431.1 Residues 7 to 179 of 179 are 91.32 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|P08407|PAPE_ECOLI FIMBRIAL PROTEIN PAPE PRECURSOR; PapE protein 3431761 papE 1039520 papE Escherichia coli CFT073 PapE protein NP_755460.1 3431222 R 199310 CDS NP_755461.1 26249421 1039523 complement(3431770..3432309) 1 NC_004431.1 Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 : >sp|P42190|PAPK_ECOLI PROTEIN PAPK PRECURSOR; PapK protein 3432309 papK 1039523 papK Escherichia coli CFT073 PapK protein NP_755461.1 3431770 R 199310 CDS NP_755462.1 26249422 1039524 3431915..3432529 1 NC_004431.1 hypothetical protein 3432529 1039524 c3587 Escherichia coli CFT073 hypothetical protein NP_755462.1 3431915 D 199310 CDS NP_755463.1 26249423 1039525 complement(3432316..3432897) 1 NC_004431.1 Residues 1 to 193 of 193 are 96.37 pct identical to residues 1 to 193 of 193 from SwissProt.40 : >sp|P42189|PRSJ_ECOLI PRSJ PROTEIN PRECURSOR; PapJ protein 3432897 papJ 1039525 papJ Escherichia coli CFT073 PapJ protein NP_755463.1 3432316 R 199310 CDS NP_755464.1 26249424 1039526 complement(3432934..3433539) 1 NC_004431.1 Residues 1 to 201 of 201 are 41.58 pct identical to residues 46 to 246 of 250 from MG1655 : b2336; PapD protein 3433539 papD 1039526 papD Escherichia coli CFT073 PapD protein NP_755464.1 3432934 R 199310 CDS NP_755465.1 26249425 1039527 complement(3433739..3436261) 1 NC_004431.1 Residues 5 to 836 of 840 are 43.20 pct identical to residues 1 to 842 of 879 from EDL933 : z3600; PapC protein 3436261 papC 1039527 papC Escherichia coli CFT073 PapC protein NP_755465.1 3433739 R 199310 CDS NP_755466.1 26249426 1039529 complement(3436308..3436895) 1 NC_004431.1 Residues 1 to 195 of 195 are 98.97 pct identical to residues 1 to 195 of 195 from SwissProt.40 : >sp|P42185|PRSH_ECOLI PRS FIMBRIAL MINOR PILIN PROTEIN PRECURSOR; PapH protein 3436895 papH 1039529 papH Escherichia coli CFT073 PapH protein NP_755466.1 3436308 R 199310 CDS NP_755467.1 26249427 1039530 complement(3436965..3437564) 1 NC_004431.1 Residues 12 to 199 of 199 are 100.00 pct identical to residues 1 to 188 of 188 from SwissProt.40 : >sp|P02972|FMF2_ECOLI F7-2 FIMBRIAL PROTEIN PRECURSOR (F7-2 PILIN); PapA protein 3437564 papA 1039530 papA Escherichia coli CFT073 PapA protein NP_755467.1 3436965 R 199310 CDS NP_755468.1 26249428 1039535 3438457..3438690 1 NC_004431.1 Residues 1 to 77 of 77 are 98.70 pct identical to residues 1 to 77 of 77 from SwissProt.40 : >sp|P25395|KS7A_ECOLI P FIMBRIAL REGULATORY PROTEIN KS71A; PapI protein 3438690 papI 1039535 papI Escherichia coli CFT073 PapI protein NP_755468.1 3438457 D 199310 CDS NP_755469.1 26249429 1039536 complement(3439254..3439772) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5880; transposase 3439772 1039536 c3594 Escherichia coli CFT073 transposase NP_755469.1 3439254 R 199310 CDS NP_755470.1 26249430 1039537 complement(3439784..3440140) 1 NC_004431.1 Residues 1 to 118 of 118 are 98.30 pct identical to residues 1 to 118 of 118 from GenPept.129 : >gb|AAC61721.1| (AF081285) transposase R14 [Escherichia coli]; transposase 3440140 1039537 c3595 Escherichia coli CFT073 transposase NP_755470.1 3439784 R 199310 CDS NP_755471.1 26249431 1039538 complement(3440140..3440466) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5879; hypothetical protein 3440466 1039538 c3596 Escherichia coli CFT073 hypothetical protein NP_755471.1 3440140 R 199310 CDS NP_755472.1 26249432 1039539 complement(3441312..3441902) 1 NC_004431.1 Residues 1 to 196 of 196 are 83.16 pct identical to residues 173 to 368 of 406 from GenPept.129 : >gb|AAF60967.1|AF188737_2 (AF188737) transposase [Escherichia coli]; transposase 3441902 1039539 c3597 Escherichia coli CFT073 transposase NP_755472.1 3441312 R 199310 CDS NP_755473.1 26249433 1039540 complement(3441905..3442066) 1 NC_004431.1 hypothetical protein 3442066 1039540 c3598 Escherichia coli CFT073 hypothetical protein NP_755473.1 3441905 R 199310 CDS NP_755474.1 26249434 1039541 3442496..3442756 1 NC_004431.1 Residues 1 to 86 of 86 are 100.00 pct identical to residues 1 to 86 of 86 from GenPept.129 : >gb|AAC61724.1| (AF081285) R10 [Escherichia coli]; hypothetical protein 3442756 1039541 c3599 Escherichia coli CFT073 hypothetical protein NP_755474.1 3442496 D 199310 CDS NP_755475.1 26249435 1039542 3442798..3443358 1 NC_004431.1 Residues 3 to 165 of 186 are 27.54 pct identical to residues 7 to 173 of 201 from GenPept.129 : >dbj|BAB76266.1| (AP003596) transcriptional regulator [Nostoc sp. PCC 7120]; hypothetical protein 3443358 1039542 c3600 Escherichia coli CFT073 hypothetical protein NP_755475.1 3442798 D 199310 CDS NP_755476.1 26249436 1039544 3443368..3443826 1 NC_004431.1 Residues 11 to 152 of 152 are 100.00 pct identical to residues 1 to 142 of 142 from GenPept.129 : >gb|AAC61725.1| (AF081285) F200 [Escherichia coli]; hypothetical protein 3443826 1039544 c3601 Escherichia coli CFT073 hypothetical protein NP_755476.1 3443368 D 199310 CDS NP_755477.1 26249437 1039547 complement(3444379..3444594) 1 NC_004431.1 hypothetical protein 3444594 1039547 c3602 Escherichia coli CFT073 hypothetical protein NP_755477.1 3444379 R 199310 CDS NP_755478.1 26249438 1039548 complement(3444598..3444981) 1 NC_004431.1 hypothetical protein 3444981 1039548 c3603 Escherichia coli CFT073 hypothetical protein NP_755478.1 3444598 R 199310 CDS NP_755479.1 26249439 1039549 3444661..3445062 1 NC_004431.1 hypothetical protein 3445062 1039549 c3604 Escherichia coli CFT073 hypothetical protein NP_755479.1 3444661 D 199310 CDS NP_755480.1 26249440 1039550 complement(3444978..3445169) 1 NC_004431.1 hypothetical protein 3445169 1039550 c3605 Escherichia coli CFT073 hypothetical protein NP_755480.1 3444978 R 199310 CDS NP_755481.1 26249441 1039551 complement(3445257..3445577) 1 NC_004431.1 hypothetical protein 3445577 1039551 c3606 Escherichia coli CFT073 hypothetical protein NP_755481.1 3445257 R 199310 CDS NP_755482.1 26249442 1039553 3445858..3447357 1 NC_004431.1 Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein 3447357 1039553 c3607 Escherichia coli CFT073 hypothetical protein NP_755482.1 3445858 D 199310 CDS NP_755483.1 26249443 1039554 3447354..3448109 1 NC_004431.1 Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 3448109 1039554 c3608 Escherichia coli CFT073 hypothetical protein NP_755483.1 3447354 D 199310 CDS NP_755484.1 26249444 1039556 complement(3448318..3448542) 1 NC_004431.1 Residues 1 to 74 of 74 are 97.29 pct identical to residues 1 to 74 of 74 from GenPept.129 : >dbj|BAB34782.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 3448542 1039556 c3609 Escherichia coli CFT073 hypothetical protein NP_755484.1 3448318 R 199310 CDS NP_755485.1 26249445 1039557 complement(3448776..3450866) 1 NC_004431.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein 3450866 1039557 c3610 Escherichia coli CFT073 bifunctional enterobactin receptor/adhesin protein NP_755485.1 3448776 R 199310 CDS NP_755486.1 26249446 1039558 complement(3451366..3452271) 1 NC_004431.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3452271 1039558 c3611 Escherichia coli CFT073 insertion element IS2 transposase InsD NP_755486.1 3451366 R 199310 CDS NP_755487.1 26249447 1039563 complement(3452264..3452638) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4272; transposase insC 3452638 1039563 c3612 Escherichia coli CFT073 transposase insC NP_755487.1 3452264 R 199310 CDS NP_755488.1 26249448 1039566 3452810..3452968 1 NC_004431.1 Residues 1 to 44 of 52 are 75.00 pct identical to residues 47 to 90 of 116 from GenPept.129 : >gb|AAG58804.1|AE005593_6 (AE005593) unknown protein encoded by IS911 within prophage CP-933L [Escherichia coli O157:H7 EDL933]; hypothetical protein 3452968 1039566 c3613 Escherichia coli CFT073 hypothetical protein NP_755488.1 3452810 D 199310 CDS NP_755489.1 26249449 1039567 complement(3452972..3453157) 1 NC_004431.1 Residues 1 to 61 of 61 are 100.00 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 3453157 1039567 c3614 Escherichia coli CFT073 hypothetical protein NP_755489.1 3452972 R 199310 CDS NP_755490.1 26249450 1039568 complement(3453103..3454584) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1600; hypothetical protein 3454584 1039568 c3615 Escherichia coli CFT073 hypothetical protein NP_755490.1 3453103 R 199310 CDS NP_755491.1 26249451 1039570 complement(3454615..3454965) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1599; hypothetical protein 3454965 1039570 c3616 Escherichia coli CFT073 hypothetical protein NP_755491.1 3454615 R 199310 CDS NP_755492.1 26249452 1039571 complement(3454962..3455399) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1648; hypothetical protein 3455399 1039571 c3617 Escherichia coli CFT073 hypothetical protein NP_755492.1 3454962 R 199310 CDS NP_755493.1 26249453 1039572 complement(3455734..3456432) 1 NC_004431.1 Residues 40 to 232 of 232 are 98.44 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAK00460.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3456432 1039572 c3618 Escherichia coli CFT073 hypothetical protein NP_755493.1 3455734 R 199310 CDS NP_755494.1 26249454 1039573 complement(3456362..3460261) 1 NC_004431.1 Residues 5 to 1299 of 1299 are 100.00 pct identical to residues 1 to 1295 of 1295 from GenPept.129 : >gb|AAG30168.1|AF289092_1 (AF289092) secreted autotransporter toxin [Escherichia coli]; secreted auto transporter toxin 3460261 sat 1039573 sat Escherichia coli CFT073 secreted auto transporter toxin NP_755494.1 3456362 R 199310 CDS NP_755497.1 26249457 1039577 3460499..3460642 1 NC_004431.1 hypothetical protein 3460642 1039577 c3622 Escherichia coli CFT073 hypothetical protein NP_755497.1 3460499 D 199310 CDS NP_755498.1 26249458 1039578 complement(3461193..3463472) 1 NC_004431.1 Residues 28 to 759 of 759 are 87.56 pct identical to residues 2 to 732 of 732 from SwissProt.40 : >sp|P14542|IUTA_ECOLI FERRIC AEROBACTIN RECEPTOR PRECURSOR (CLOACIN RECEPTOR); IutA protein 3463472 iutA 1039578 iutA Escherichia coli CFT073 IutA protein NP_755498.1 3461193 R 199310 CDS NP_755499.1 26249459 1039579 complement(3463394..3464731) 1 NC_004431.1 Residues 1 to 425 of 445 are 97.88 pct identical to residues 1 to 425 of 425 from SwissProt.40 : >sp|P11295|IUCD_ECOLI L-LYSINE 6-MONOOXYGENASE (LYSINE N6-HYDROXYLASE); IucD protein 3464731 iucD 1039579 iucD Escherichia coli CFT073 IucD protein NP_755499.1 3463394 R 199310 CDS NP_755500.1 26249460 1039580 complement(3464728..3466470) 1 NC_004431.1 Residues 1 to 580 of 580 are 96.89 pct identical to residues 1 to 580 of 580 from SwissProt.40 : >sp|Q47318|IUCC_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCC; IucC protein 3466470 iucC 1039580 iucC Escherichia coli CFT073 IucC protein NP_755500.1 3464728 R 199310 CDS NP_755501.1 26249461 1039581 complement(3466470..3467417) 1 NC_004431.1 Residues 1 to 315 of 315 are 94.92 pct identical to residues 1 to 315 of 315 from SwissProt.40 : >sp|Q47317|IUCB_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCB; IucB protein 3467417 iucB 1039581 iucB Escherichia coli CFT073 IucB protein NP_755501.1 3466470 R 199310 CDS NP_755502.1 26249462 1039582 complement(3467418..3469205) 1 NC_004431.1 Residues 22 to 595 of 595 are 93.04 pct identical to residues 1 to 575 of 575 from SwissProt.40 : >sp|Q47316|IUCA_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCA; IucA protein 3469205 iucA 1039582 iucA Escherichia coli CFT073 IucA protein NP_755502.1 3467418 R 199310 CDS NP_755503.1 26249463 1039583 3469278..3470471 1 NC_004431.1 Residues 1 to 397 of 397 are 99.74 pct identical to residues 1 to 397 of 397 from GenPept.129 : >gb|AAD44744.1|AF141323_15 (AF141323) ShiF [Shigella flexneri]; shiF protein 3470471 shiF 1039583 shiF Escherichia coli CFT073 shiF protein NP_755503.1 3469278 D 199310 CDS NP_755504.1 26249464 1039586 complement(3469679..3469801) 1 NC_004431.1 hypothetical protein 3469801 1039586 c3629 Escherichia coli CFT073 hypothetical protein NP_755504.1 3469679 R 199310 CDS NP_755505.1 26249465 1039587 complement(3470630..3471619) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4309; hypothetical protein 3471619 1039587 c3630 Escherichia coli CFT073 hypothetical protein NP_755505.1 3470630 R 199310 CDS NP_755506.1 26249466 1039589 complement(3471917..3472081) 1 NC_004431.1 hypothetical protein 3472081 1039589 c3631 Escherichia coli CFT073 hypothetical protein NP_755506.1 3471917 R 199310 CDS NP_755507.1 26249467 1039590 complement(3472357..3472488) 1 NC_004431.1 hypothetical protein 3472488 1039590 c3632 Escherichia coli CFT073 hypothetical protein NP_755507.1 3472357 R 199310 CDS NP_755508.1 26249468 1039591 complement(3472475..3473413) 1 NC_004431.1 Residues 55 to 310 of 312 are 37.89 pct identical to residues 73 to 327 of 328 from GenPept.129 : >gb|AAK24284.1| (AE005901) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 3473413 1039591 c3633 Escherichia coli CFT073 hypothetical protein NP_755508.1 3472475 R 199310 CDS NP_755509.1 26249469 1039593 complement(3473463..3474581) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4310; Escherichia coli O157:H7 ortholog: z5906; N-acetylneuraminic acid mutarotase 3474581 1039593 c3634 Escherichia coli CFT073 N-acetylneuraminic acid mutarotase NP_755509.1 3473463 R 199310 CDS NP_755510.1 26249470 1039594 complement(3474585..3475325) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4311; Escherichia coli O157:H7 ortholog: z5907; hypothetical protein 3475325 1039594 c3635 Escherichia coli CFT073 hypothetical protein NP_755510.1 3474585 R 199310 CDS NP_755511.1 26249471 1039596 complement(3475341..3476150) 1 NC_004431.1 Residues 37 to 266 of 269 are 40.65 pct identical to residues 81 to 326 of 328 from GenPept.129 : >gb|AAK24284.1| (AE005901) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 3476150 1039596 c3636 Escherichia coli CFT073 hypothetical protein NP_755511.1 3475341 R 199310 CDS NP_755512.2 161486122 1039597 complement(3476175..3477647) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3224; Escherichia coli O157:H7 ortholog: z4582; sialic acid transporter 3477647 1039597 c3637 Escherichia coli CFT073 sialic acid transporter NP_755512.2 3476175 R 199310 CDS NP_755513.1 26249473 1039598 complement(3477696..3478571) 1 NC_004431.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3478571 1039598 c3638 Escherichia coli CFT073 N-acetylmannosamine kinase NP_755513.1 3477696 R 199310 CDS NP_755514.1 26249474 1039599 complement(3478605..3479522) 1 NC_004431.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3479522 1039599 c3639 Escherichia coli CFT073 N-acetylneuraminate lyase NP_755514.1 3478605 R 199310 CDS NP_755515.1 26249475 1039601 3480253..3480615 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1598; hypothetical protein 3480615 1039601 c3640 Escherichia coli CFT073 hypothetical protein NP_755515.1 3480253 D 199310 CDS NP_755516.1 26249476 1039602 3480612..3480962 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1599; hypothetical protein 3480962 1039602 c3641 Escherichia coli CFT073 hypothetical protein NP_755516.1 3480612 D 199310 CDS NP_755517.1 26249477 1039603 complement(3480627..3480971) 1 NC_004431.1 hypothetical protein 3480971 1039603 c3642 Escherichia coli CFT073 hypothetical protein NP_755517.1 3480627 R 199310 CDS NP_755518.1 26249478 1039604 3480993..3482093 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1600; hypothetical protein 3482093 1039604 c3643 Escherichia coli CFT073 hypothetical protein NP_755518.1 3480993 D 199310 CDS NP_755519.1 26249479 1039605 complement(3481920..3482084) 1 NC_004431.1 hypothetical protein 3482084 1039605 c3644 Escherichia coli CFT073 hypothetical protein NP_755519.1 3481920 R 199310 CDS NP_755520.1 26249480 1039607 3482090..3483628 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5098; hypothetical protein 3483628 1039607 c3645 Escherichia coli CFT073 hypothetical protein NP_755520.1 3482090 D 199310 CDS NP_755521.1 26249481 1039608 complement(3483544..3483738) 1 NC_004431.1 Residues 26 to 64 of 64 are 100.00 pct identical to residues 89 to 127 of 127 from GenPept.129 : >gb|AAD30026.1|AF119170_1 (AF119170) truncated BfpA [Escherichia coli]; hypothetical protein 3483738 1039608 c3646 Escherichia coli CFT073 hypothetical protein NP_755521.1 3483544 R 199310 CDS NP_755522.1 26249482 1039613 complement(3483812..3484267) 1 NC_004431.1 Residues 13 to 136 of 151 are 91.12 pct identical to residues 1 to 124 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3484267 1039613 c3647 Escherichia coli CFT073 hypothetical protein NP_755522.1 3483812 R 199310 CDS NP_755523.1 26249483 1039616 complement(3484397..3484966) 1 NC_004431.1 Residues 5 to 189 of 189 are 39.56 pct identical to residues 6 to 235 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 3484966 1039616 c3648 Escherichia coli CFT073 hypothetical protein NP_755523.1 3484397 R 199310 CDS NP_755524.1 26249484 1039618 complement(3485694..3485918) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0460; Escherichia coli O157:H7 ortholog: z0573; hemolysin expression modulating protein 3485918 1039618 c3649 Escherichia coli CFT073 hemolysin expression modulating protein NP_755524.1 3485694 R 199310 CDS NP_755525.1 26249485 1039619 3486747..3487007 1 NC_004431.1 Residues 11 to 86 of 86 are 96.05 pct identical to residues 17 to 92 of 92 from GenPept.129 : >gb|AAL08466.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3487007 1039619 c3650 Escherichia coli CFT073 hypothetical protein NP_755525.1 3486747 D 199310 CDS NP_755526.1 26249486 1039621 3487066..3487665 1 NC_004431.1 Residues 28 to 199 of 199 are 97.67 pct identical to residues 1 to 172 of 172 from GenPept.129 : >gb|AAK00471.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3487665 1039621 c3651 Escherichia coli CFT073 hypothetical protein NP_755526.1 3487066 D 199310 CDS NP_755527.1 26249487 1039622 complement(3487786..3489294) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2625; hypothetical protein 3489294 1039622 c3652 Escherichia coli CFT073 hypothetical protein NP_755527.1 3487786 R 199310 CDS NP_755528.1 26249488 1039646 complement(3489471..3489692) 1 NC_004431.1 hypothetical protein 3489692 1039646 c3653 Escherichia coli CFT073 hypothetical protein NP_755528.1 3489471 R 199310 CDS NP_755529.1 26249489 1039679 3490608..3491480 1 NC_004431.1 Escherichia coli K-12 ortholog: b1999; Escherichia coli O157:H7 ortholog: z1650; hypothetical protein 3491480 1039679 c3654 Escherichia coli CFT073 hypothetical protein NP_755529.1 3490608 D 199310 CDS NP_755530.1 26249490 1039680 3491808..3494936 1 NC_004431.1 AG43; Sap; Escherichia coli K-12 ortholog: b2000; Escherichia coli O157:H7 ortholog: z1651; antigen 43 3494936 1039680 c3655 Escherichia coli CFT073 antigen 43 NP_755530.1 3491808 D 199310 CDS NP_755531.1 26249491 1039681 3495115..3495444 1 NC_004431.1 Residues 1 to 109 of 109 are 68.80 pct identical to residues 1 to 109 of 109 from GenPept.129 : >dbj|BAB34765.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 3495444 1039681 c3656 Escherichia coli CFT073 hypothetical protein NP_755531.1 3495115 D 199310 CDS NP_755532.1 26249492 1039682 3495431..3495823 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1602; hypothetical protein 3495823 1039682 c3657 Escherichia coli CFT073 hypothetical protein NP_755532.1 3495431 D 199310 CDS NP_755533.1 26249493 1039683 3495830..3497431 1 NC_004431.1 Residues 13 to 298 of 533 are 71.32 pct identical to residues 1 to 277 of 285 from GenPept.129 : >gb|AAG55716.1|AE005309_6 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 3497431 1039683 c3658 Escherichia coli CFT073 hypothetical protein NP_755533.1 3495830 D 199310 CDS NP_755534.1 26249494 1039684 3497824..3498471 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4315; hypothetical protein 3498471 1039684 c3659 Escherichia coli CFT073 hypothetical protein NP_755534.1 3497824 D 199310 CDS NP_755535.1 26249495 1039685 3498471..3498818 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4316; hypothetical protein 3498818 1039685 c3660 Escherichia coli CFT073 hypothetical protein NP_755535.1 3498471 D 199310 CDS NP_755536.1 26249496 1039686 complement(3498552..3498731) 1 NC_004431.1 hypothetical protein 3498731 1039686 c3661 Escherichia coli CFT073 hypothetical protein NP_755536.1 3498552 R 199310 CDS NP_755537.1 26249497 1039687 3498838..3499941 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4317; hypothetical protein 3499941 1039687 c3662 Escherichia coli CFT073 hypothetical protein NP_755537.1 3498838 D 199310 CDS NP_755538.1 26249498 1039689 3500024..3500404 1 NC_004431.1 Residues 1 to 126 of 126 are 95.23 pct identical to residues 398 to 523 of 523 from GenPept.129 : >dbj|BAA84886.1| (AB024946) orf51 [Escherichia coli]; hypothetical protein 3500404 1039689 c3663 Escherichia coli CFT073 hypothetical protein NP_755538.1 3500024 D 199310 CDS NP_755539.1 26249499 1039690 3500527..3503049 1 NC_004431.1 Escherichia coli K-12 ortholog: b2001; hypothetical protein 3503049 1039690 c3664 Escherichia coli CFT073 hypothetical protein NP_755539.1 3500527 D 199310 CDS NP_755540.1 26249500 1039691 3503125..3503580 1 NC_004431.1 Residues 9 to 151 of 151 are 98.60 pct identical to residues 1 to 143 of 143 from GenPept.129 : >gb|AAK00476.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3503580 1039691 c3665 Escherichia coli CFT073 hypothetical protein NP_755540.1 3503125 D 199310 CDS NP_755541.1 26249501 1039695 3503659..3503892 1 NC_004431.1 Escherichia coli K-12 ortholog: b0249; hypothetical protein 3503892 1039695 c3666 Escherichia coli CFT073 hypothetical protein NP_755541.1 3503659 D 199310 CDS NP_755542.1 26249502 1039696 complement(3503701..3503889) 1 NC_004431.1 hypothetical protein 3503889 1039696 c3667 Escherichia coli CFT073 hypothetical protein NP_755542.1 3503701 R 199310 CDS NP_755543.1 26249503 1039697 3503993..3504811 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 3504811 1039697 c3668 Escherichia coli CFT073 hypothetical protein NP_755543.1 3503993 D 199310 CDS NP_755544.1 26249504 1039698 3504866..3505351 1 NC_004431.1 Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 3505351 1039698 c3669 Escherichia coli CFT073 hypothetical protein NP_755544.1 3504866 D 199310 CDS NP_755545.1 26249505 1039700 complement(3504920..3505831) 1 NC_004431.1 Residues 1 to 298 of 303 are 93.28 pct identical to residues 1 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 3505831 1039700 c3670 Escherichia coli CFT073 hypothetical protein NP_755545.1 3504920 R 199310 CDS NP_755546.1 26249506 1039702 3505352..3505843 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 3505843 1039702 c3671 Escherichia coli CFT073 radC-like protein yeeS NP_755546.1 3505352 D 199310 CDS NP_755547.1 26249507 1039703 complement(3505840..3506568) 1 NC_004431.1 Residues 140 to 221 of 242 are 40.24 pct identical to residues 71 to 152 of 164 from GenPept.129 : >gb|AAB08666.1| (U70214) hypothetical protein [Escherichia coli]; hypothetical protein 3506568 1039703 c3672 Escherichia coli CFT073 hypothetical protein NP_755547.1 3505840 R 199310 CDS NP_755548.1 26249508 1039705 3505906..3506127 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z3163; hypothetical protein 3506127 1039705 c3673 Escherichia coli CFT073 hypothetical protein NP_755548.1 3505906 D 199310 CDS NP_755549.1 26249509 1039706 3506146..3506790 1 NC_004431.1 Residues 178 to 214 of 214 are 78.37 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein 3506790 1039706 c3674 Escherichia coli CFT073 hypothetical protein NP_755549.1 3506146 D 199310 CDS NP_755550.1 26249510 1039709 complement(3506813..3507376) 1 NC_004431.1 Residues 92 to 160 of 187 are 82.60 pct identical to residues 1 to 69 of 176 from GenPept.129 : >gb|AAL67390.1|AF447814_58 (AF447814) unknown [Escherichia coli]; hypothetical protein 3507376 1039709 c3675 Escherichia coli CFT073 hypothetical protein NP_755550.1 3506813 R 199310 CDS NP_755551.1 26249511 1039710 3506840..3507220 1 NC_004431.1 Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein 3507220 1039710 c3676 Escherichia coli CFT073 hypothetical protein NP_755551.1 3506840 D 199310 CDS NP_755552.1 26249512 1039711 3507297..3507674 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 3507674 1039711 c3677 Escherichia coli CFT073 hypothetical protein NP_755552.1 3507297 D 199310 CDS NP_755553.1 26249513 1039713 3507671..3508159 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1662; hypothetical protein 3508159 1039713 c3678 Escherichia coli CFT073 hypothetical protein NP_755553.1 3507671 D 199310 CDS NP_755554.1 26249514 1039715 3508176..3508373 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1663; hypothetical protein 3508373 1039715 c3679 Escherichia coli CFT073 hypothetical protein NP_755554.1 3508176 D 199310 CDS NP_755555.1 26249515 1039716 3508458..3509303 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 3509303 1039716 c3680 Escherichia coli CFT073 hypothetical protein NP_755555.1 3508458 D 199310 CDS NP_755556.1 26249516 1039720 3509372..3509767 1 NC_004431.1 hypothetical protein 3509767 1039720 c3681 Escherichia coli CFT073 hypothetical protein NP_755556.1 3509372 D 199310 CDS NP_755557.1 26249517 1039721 3509760..3510677 1 NC_004431.1 hypothetical protein 3510677 1039721 c3682 Escherichia coli CFT073 hypothetical protein NP_755557.1 3509760 D 199310 CDS NP_755558.1 26249518 1039722 3510482..3510694 1 NC_004431.1 hypothetical protein 3510694 1039722 c3683 Escherichia coli CFT073 hypothetical protein NP_755558.1 3510482 D 199310 CDS NP_755559.1 26249519 1039723 3511126..3511281 1 NC_004431.1 Residues 9 to 51 of 51 are 76.74 pct identical to residues 64 to 106 of 112 from GenPept.129 : >gb|AAK18488.1|AF348706_177 (AF348706) transposase [Shigella flexneri]; hypothetical protein 3511281 1039723 c3684 Escherichia coli CFT073 hypothetical protein NP_755559.1 3511126 D 199310 CDS NP_755560.1 26249520 1039724 complement(3511449..3511592) 1 NC_004431.1 hypothetical protein 3511592 1039724 c3685 Escherichia coli CFT073 hypothetical protein NP_755560.1 3511449 R 199310 CDS NP_755561.1 26249521 1039725 3512056..3513075 1 NC_004431.1 Escherichia coli K-12 ortholog: b3197; Escherichia coli O157:H7 ortholog: z4560; hypothetical protein 3513075 1039725 c3686 Escherichia coli CFT073 hypothetical protein NP_755561.1 3512056 D 199310 CDS NP_755562.1 26249522 1039726 3513147..3514295 1 NC_004431.1 Residues 1 to 382 of 382 are 100.00 pct identical to residues 1 to 382 of 382 from SwissProt.40 : >sp|P42214|KSE5_ECOLI CAPSULE POLYSACCHARIDE EXPORT INNER-MEMBRANE PROTEIN KPSE; KpsE protein 3514295 kpsE 1039726 kpsE Escherichia coli CFT073 KpsE protein NP_755562.1 3513147 D 199310 CDS NP_755563.1 26249523 1039727 3514316..3515995 1 NC_004431.1 Residues 2 to 559 of 559 are 99.46 pct identical to residues 1 to 558 of 558 from SwissProt.40 : >sp|P42213|KSD5_ECOLI POLYSIALIC ACID TRANSPORT PROTEIN KPSD PRECURSOR; KpsD protein 3515995 kpsD 1039727 kpsD Escherichia coli CFT073 KpsD protein NP_755563.1 3514316 D 199310 CDS NP_755564.1 26249524 1039728 3516005..3516745 1 NC_004431.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3516745 1039728 c3689 Escherichia coli CFT073 3-deoxy-manno-octulosonate cytidylyltransferase NP_755564.1 3516005 D 199310 CDS NP_755565.1 26249525 1039730 3516742..3518769 1 NC_004431.1 Residues 1 to 675 of 675 are 96.29 pct identical to residues 1 to 675 of 675 from SwissProt.40 : >sp|P42217|KSC5_ECOLI Capsule polysaccharide export protein KPSC; KpsC protein 3518769 kpsC 1039730 kpsC Escherichia coli CFT073 KpsC protein NP_755565.1 3516742 D 199310 CDS NP_755566.1 26249526 1039731 3518804..3520042 1 NC_004431.1 Residues 1 to 389 of 412 are 97.17 pct identical to residues 1 to 389 of 389 from SwissProt.40 : >sp|P42218|KSS5_ECOLI CAPSULE POLYSACCHARIDE EXPORT PROTEIN KPSS; KpsS protein 3520042 kpsS 1039731 kpsS Escherichia coli CFT073 KpsS protein NP_755566.1 3518804 D 199310 CDS NP_755567.1 26249527 1039732 complement(3520204..3521199) 1 NC_004431.1 hypothetical protein 3521199 1039732 c3692 Escherichia coli CFT073 hypothetical protein NP_755567.1 3520204 R 199310 CDS NP_755568.1 26249528 1039733 complement(3521205..3522233) 1 NC_004431.1 Residues 11 to 332 of 342 are 23.26 pct identical to residues 225 to 543 of 543 from GenPept.129 : >gb|AAK05018.1|AE006326_9 (AE006326) UNKNOWN PROTEIN [Lactococcus lactis subsp. lactis]; hypothetical protein 3522233 1039733 c3693 Escherichia coli CFT073 hypothetical protein NP_755568.1 3521205 R 199310 CDS NP_755569.1 26249529 1039734 complement(3522336..3526136) 1 NC_004431.1 Residues 495 to 1078 of 1266 are 33.16 pct identical to residues 10 to 602 of 807 from GenPept.129 : >gb|AAK05019.1|AE006326_10 (AE006326) teichoic acid biosynthesis protein [Lactococcus lactis subsp. lactis]; hypothetical protein 3526136 1039734 c3694 Escherichia coli CFT073 hypothetical protein NP_755569.1 3522336 R 199310 CDS NP_755570.1 26249530 1039735 complement(3526190..3527425) 1 NC_004431.1 Residues 210 to 367 of 411 are 29.10 pct identical to residues 50 to 232 of 246 from GenPept.129 : >dbj|BAB80328.1| (AP003187) hypothetical protein [Clostridium perfringens]; hypothetical protein 3527425 1039735 c3695 Escherichia coli CFT073 hypothetical protein NP_755570.1 3526190 R 199310 CDS NP_755571.1 26249531 1039736 complement(3527441..3527848) 1 NC_004431.1 Residues 5 to 131 of 135 are 49.60 pct identical to residues 1 to 126 of 129 from SwissProt.40 : >sp|P27623|TAGD_BACSU Glycerol-3-phosphate cytidylyltransferase (GCT) (CDP-glycerol pyrophosphorylase) (Teichoic acid biosynthesis protein D); glycerol-3-phosphate cytidyltransferase 3527848 1039736 c3696 Escherichia coli CFT073 glycerol-3-phosphate cytidyltransferase NP_755571.1 3527441 R 199310 CDS NP_755572.1 26249532 1039737 complement(3527848..3528519) 1 NC_004431.1 Residues 1 to 223 of 223 are 88.78 pct identical to residues 1 to 223 of 224 from SwissProt.40 : >sp|P24586|KST5_ECOLI POLYSIALIC ACID TRANSPORT ATP-BINDING PROTEIN KPST; KpsT protein 3528519 kpsT 1039737 kpsT Escherichia coli CFT073 KpsT protein NP_755572.1 3527848 R 199310 CDS NP_755573.1 26249533 1039739 complement(3528516..3529292) 1 NC_004431.1 Residues 1 to 258 of 258 are 96.89 pct identical to residues 1 to 258 of 258 from SwissProt.40 : >sp|P24584|KPM2_ECOLI POLYSIALIC ACID TRANSPORT PROTEIN KPSM; KpsM protein 3529292 kpsM 1039739 kpsM Escherichia coli CFT073 KpsM protein NP_755573.1 3528516 R 199310 CDS NP_755574.1 26249534 1039740 complement(3530466..3531002) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2968; general secretion pathway protein YghD 3531002 yghD 1039740 yghD Escherichia coli CFT073 general secretion pathway protein YghD NP_755574.1 3530466 R 199310 CDS NP_755575.1 26249535 1039744 complement(3532178..3532591) 1 NC_004431.1 Residues 1 to 137 of 137 are 98.54 pct identical to residues 189 to 325 of 325 from GenPept.129 : >gb|AAL60191.1|AF426313_11 (AF426313) hypothetical type II secretion protein GspK [Escherichia coli]; hypothetical protein 3532591 1039744 c3702 Escherichia coli CFT073 hypothetical protein NP_755575.1 3532178 R 199310 CDS NP_755576.1 26249536 1039745 complement(3532771..3534120) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4278; transposase insG 3534120 1039745 c3703 Escherichia coli CFT073 transposase insG NP_755576.1 3532771 R 199310 CDS NP_755577.1 26249537 1039746 complement(3534256..3535938) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2975; Escherichia coli O157:H7 ortholog: z5030; glycolate transporter 3535938 yghK 1039746 yghK Escherichia coli CFT073 glycolate transporter NP_755577.1 3534256 R 199310 CDS NP_755578.1 26249538 1039747 complement(3536293..3538464) 1 NC_004431.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3538464 glcB 1039747 glcB Escherichia coli CFT073 malate synthase G NP_755578.1 3536293 R 199310 CDS NP_755579.1 26249539 1039748 complement(3538486..3538908) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2977; hypothetical protein 3538908 glcG 1039748 glcG Escherichia coli CFT073 hypothetical protein NP_755579.1 3538486 R 199310 CDS NP_755580.1 26249540 1039751 complement(3541181..3542680) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2979; glycolate oxidase subunit GlcD 3542680 glcD 1039751 glcD Escherichia coli CFT073 glycolate oxidase subunit GlcD NP_755580.1 3541181 R 199310 CDS NP_755581.1 26249541 1039754 3542871..3543695 1 NC_004431.1 Escherichia coli K-12 ortholog: b2980; DNA-binding transcriptional regulator GlcC 3543695 glcC 1039754 glcC Escherichia coli CFT073 DNA-binding transcriptional regulator GlcC NP_755581.1 3542871 D 199310 CDS NP_755582.1 26249542 1039755 complement(3543702..3544910) 1 NC_004431.1 Fragment; Escherichia coli K-12 ortholog: b2981; hypothetical protein 3544910 yghO 1039755 yghO Escherichia coli CFT073 hypothetical protein NP_755582.1 3543702 R 199310 CDS NP_755583.1 26249543 1039758 3545212..3546942 1 NC_004431.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3546942 1039758 c3712 Escherichia coli CFT073 acyl-CoA synthetase NP_755583.1 3545212 D 199310 CDS NP_755584.1 26249544 1039760 3546939..3547853 1 NC_004431.1 Residues 5 to 287 of 304 are 33.21 pct identical to residues 9 to 288 of 317 from GenPept.129 : >gb|AAK23148.1| (AE005794) conserved hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 3547853 1039760 c3713 Escherichia coli CFT073 hypothetical protein NP_755584.1 3546939 D 199310 CDS NP_755585.1 26249545 1039764 3547885..3548133 1 NC_004431.1 hypothetical protein 3548133 1039764 c3714 Escherichia coli CFT073 hypothetical protein NP_755585.1 3547885 D 199310 CDS NP_755586.1 26249546 1039767 3548133..3549305 1 NC_004431.1 Residues 1 to 388 of 390 are 53.47 pct identical to residues 1 to 389 of 404 from GenPept.129 : >gb|AAK23146.1| (AE005794) aminotransferase, class II [Caulobacter crescentus CB15]; hypothetical protein 3549305 1039767 c3715 Escherichia coli CFT073 hypothetical protein NP_755586.1 3548133 D 199310 CDS NP_755587.1 26249547 1039768 complement(3549340..3550500) 1 NC_004431.1 Residues 30 to 379 of 386 are 29.17 pct identical to residues 4 to 354 of 358 from GenPept.129 : >emb|CAC92669.1| (AJ414157) membrane protein [Yersinia pestis]; hypothetical protein 3550500 1039768 c3716 Escherichia coli CFT073 hypothetical protein NP_755587.1 3549340 R 199310 CDS NP_755588.1 26249548 1039775 complement(3550416..3551486) 1 NC_004431.1 Residues 3 to 342 of 356 are 29.54 pct identical to residues 2 to 350 of 372 from GenPept.129 : >gb|AAG07215.1|AE004800_4 (AE004800) conserved hypothetical protein [Pseudomonas aeruginosa]; hypothetical protein 3551486 1039775 c3717 Escherichia coli CFT073 hypothetical protein NP_755588.1 3550416 R 199310 CDS NP_755589.1 26249549 1039776 complement(3551517..3552080) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4216; Escherichia coli O157:H7 ortholog: z5827; hypothetical protein 3552080 1039776 c3718 Escherichia coli CFT073 hypothetical protein NP_755589.1 3551517 R 199310 CDS NP_755590.1 26249550 1039777 complement(3552089..3552913) 1 NC_004431.1 hypothetical protein 3552913 1039777 c3719 Escherichia coli CFT073 hypothetical protein NP_755590.1 3552089 R 199310 CDS NP_755591.1 26249551 1039778 complement(3552913..3554262) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2983; hypothetical protein 3554262 yghQ 1039778 yghQ Escherichia coli CFT073 hypothetical protein NP_755591.1 3552913 R 199310 CDS NP_755592.1 26249552 1039780 complement(3554308..3555066) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2984; ATP-binding protein yghR 3555066 yghR 1039780 yghR Escherichia coli CFT073 ATP-binding protein yghR NP_755592.1 3554308 R 199310 CDS NP_755593.1 26249553 1039781 complement(3555098..3555811) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2985; ATP-binding protein yghS 3555811 yghS 1039781 yghS Escherichia coli CFT073 ATP-binding protein yghS NP_755593.1 3555098 R 199310 CDS NP_755594.1 26249554 1039782 3555986..3556678 1 NC_004431.1 Escherichia coli K-12 ortholog: b2986; ATP-binding protein yghT 3556678 yghT 1039782 yghT Escherichia coli CFT073 ATP-binding protein yghT NP_755594.1 3555986 D 199310 CDS NP_755595.1 26249555 1039783 complement(3556727..3558226) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2987; Escherichia coli O157:H7 ortholog: z4893; inorganic phosphate transporter 3558226 pitB 1039783 pitB Escherichia coli CFT073 inorganic phosphate transporter NP_755595.1 3556727 R 199310 CDS NP_755596.1 26249556 1039784 complement(3558518..3560380) 1 NC_004431.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3560380 gsp 1039784 gsp Escherichia coli CFT073 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase NP_755596.1 3558518 R 199310 CDS NP_755597.1 26249557 1039785 3560534..3561448 1 NC_004431.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 3561448 yghU 1039785 yghU Escherichia coli CFT073 glutathione S-transferase YghU NP_755597.1 3560534 D 199310 CDS NP_755598.1 26249558 1039786 complement(3561590..3561838) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2990; Escherichia coli O157:H7 ortholog: z4344; hydrogenase 2 accessory protein HypG 3561838 hybG 1039786 hybG Escherichia coli CFT073 hydrogenase 2 accessory protein HypG NP_755598.1 3561590 R 199310 CDS NP_755599.1 26249559 1039787 complement(3561851..3562192) 1 NC_004431.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3562192 hypA 1039787 hypA Escherichia coli CFT073 hydrogenase nickel incorporation protein HybF NP_755599.1 3561851 R 199310 CDS NP_755600.1 26249560 1039788 complement(3562185..3562673) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2992; Escherichia coli O157:H7 ortholog: z4346; hydrogenase 2-specific chaperone 3562673 hybE 1039788 hybE Escherichia coli CFT073 hydrogenase 2-specific chaperone NP_755600.1 3562185 R 199310 CDS NP_755601.1 26249561 1039789 complement(3562666..3563160) 1 NC_004431.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3563160 hybD 1039789 hybD Escherichia coli CFT073 hydrogenase 2 maturation endopeptidase NP_755601.1 3562666 R 199310 CDS NP_755602.1 26249562 1039790 complement(3563160..3564863) 1 NC_004431.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3564863 hybC 1039790 hybC Escherichia coli CFT073 hydrogenase 2 large subunit NP_755602.1 3563160 R 199310 CDS NP_755603.1 26249563 1039791 complement(3564860..3566038) 1 NC_004431.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3566038 hybB 1039791 hybB Escherichia coli CFT073 hydrogenase 2 b cytochrome subunit NP_755603.1 3564860 R 199310 CDS NP_755604.1 26249564 1039793 complement(3566028..3567014) 1 NC_004431.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3567014 hybA 1039793 hybA Escherichia coli CFT073 hydrogenase 2 protein HybA NP_755604.1 3566028 R 199310 CDS NP_755605.1 26249565 1039794 complement(3567017..3568135) 1 NC_004431.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3568135 1039794 c3734 Escherichia coli CFT073 hydrogenase 2 small subunit NP_755605.1 3567017 R 199310 CDS NP_755606.1 26249566 1039795 complement(3568324..3568611) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2998; Escherichia coli O157:H7 ortholog: z4352; hypothetical protein 3568611 yghW 1039795 yghW Escherichia coli CFT073 hypothetical protein NP_755606.1 3568324 R 199310 CDS NP_755607.1 26249567 1039796 complement(3568730..3569656) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4353; hypothetical protein 3569656 1039796 c3736 Escherichia coli CFT073 hypothetical protein NP_755607.1 3568730 R 199310 CDS NP_755608.1 26249568 1039797 3569774..3570814 1 NC_004431.1 Escherichia coli K-12 ortholog: b3001; Escherichia coli O157:H7 ortholog: z4354; aldo/keto reductase 3570814 yghZ 1039797 yghZ Escherichia coli CFT073 aldo/keto reductase NP_755608.1 3569774 D 199310 CDS NP_755609.1 26249569 1039798 complement(3570854..3571378) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3002; Escherichia coli O157:H7 ortholog: z4355; hypothetical protein 3571378 yqhA 1039798 yqhA Escherichia coli CFT073 hypothetical protein NP_755609.1 3570854 R 199310 CDS NP_755610.1 26249570 1039799 3571536..3572423 1 NC_004431.1 Escherichia coli K-12 ortholog: b3003; Escherichia coli O157:H7 ortholog: z4356; oxidoreductase 3572423 yghA 1039799 yghA Escherichia coli CFT073 oxidoreductase NP_755610.1 3571536 D 199310 CDS NP_755611.1 26249571 1039801 complement(3572462..3572887) 1 NC_004431.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3572887 exbD 1039801 exbD Escherichia coli CFT073 biopolymer transport protein ExbD NP_755611.1 3572462 R 199310 CDS NP_755612.1 26249572 1039802 complement(3572894..3573628) 1 NC_004431.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3573628 exbB 1039802 exbB Escherichia coli CFT073 biopolymer transport protein ExbB NP_755612.1 3572894 R 199310 CDS NP_755613.1 26249573 1039803 3573745..3575067 1 NC_004431.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3575067 metC 1039803 metC Escherichia coli CFT073 cystathionine beta-lyase NP_755613.1 3573745 D 199310 CDS NP_755614.1 26249574 1039804 3575207..3575866 1 NC_004431.1 Escherichia coli K-12 ortholog: b3009; Escherichia coli O157:H7 ortholog: z4362; hypothetical protein 3575866 yghB 1039804 yghB Escherichia coli CFT073 hypothetical protein NP_755614.1 3575207 D 199310 CDS NP_755615.1 26249575 1039805 complement(3575906..3577033) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3010; Escherichia coli O157:H7 ortholog: z4363; transcriptional regulator YqhC 3577033 yqhC 1039805 yqhC Escherichia coli CFT073 transcriptional regulator YqhC NP_755615.1 3575906 R 199310 CDS NP_755616.1 26249576 1039806 3576999..3578162 1 NC_004431.1 Escherichia coli K-12 ortholog: b3011; Escherichia coli O157:H7 ortholog: z4364; oxidoreductase yqhD 3578162 yqhD 1039806 yqhD Escherichia coli CFT073 oxidoreductase yqhD NP_755616.1 3576999 D 199310 CDS NP_755617.1 26249577 1039807 3578267..3579094 1 NC_004431.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3579094 dkgA 1039807 dkgA Escherichia coli CFT073 2,5-diketo-D-gluconate reductase A NP_755617.1 3578267 D 199310 CDS NP_755618.1 26249578 1039808 3579568..3580221 1 NC_004431.1 Escherichia coli K-12 ortholog: b3013; Escherichia coli O157:H7 ortholog: z4368; hypothetical protein 3580221 yqhG 1039808 yqhG Escherichia coli CFT073 hypothetical protein NP_755618.1 3579568 D 199310 CDS NP_755619.1 26249579 1039810 3580272..3580529 1 NC_004431.1 Escherichia coli K-12 ortholog: b3014; Escherichia coli O157:H7 ortholog: z4369; outer membrane lipoprotein 3580529 yqhH 1039810 yqhH Escherichia coli CFT073 outer membrane lipoprotein NP_755619.1 3580272 D 199310 CDS NP_755620.1 26249580 1039811 complement(3580571..3582790) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4370; hypothetical protein 3582790 1039811 c3749 Escherichia coli CFT073 hypothetical protein NP_755620.1 3580571 R 199310 CDS NP_755621.1 26249581 1039812 3583042..3583791 1 NC_004431.1 Residues 1 to 248 of 249 are 78.62 pct identical to residues 18 to 265 of 266 from GenPept.129 : >gb|AAL21959.1| (AE008842) regulatory protein, gntR family [Salmonella typhimurium LT2]; regulator 3583791 1039812 c3750 Escherichia coli CFT073 regulator NP_755621.1 3583042 D 199310 CDS NP_755622.1 26249582 1039813 3584078..3585586 1 NC_004431.1 Escherichia coli K-12 ortholog: b1542; Escherichia coli O157:H7 ortholog: z2155; oxidoreductase ydfI 3585586 1039813 c3751 Escherichia coli CFT073 oxidoreductase ydfI NP_755622.1 3584078 D 199310 CDS NP_755623.1 26249583 1039814 3585583..3586599 1 NC_004431.1 Escherichia coli K-12 ortholog: b4358; Escherichia coli O157:H7 ortholog: z5958; hypothetical protein 3586599 1039814 c3752 Escherichia coli CFT073 hypothetical protein NP_755623.1 3585583 D 199310 CDS NP_755624.1 26249584 1039815 3586610..3587620 1 NC_004431.1 Escherichia coli K-12 ortholog: b0517; Escherichia coli O157:H7 ortholog: z0672; ureidoglycolate dehydrogenase 3587620 1039815 c3753 Escherichia coli CFT073 ureidoglycolate dehydrogenase NP_755624.1 3586610 D 199310 CDS NP_755625.1 26249585 1039816 3587693..3588676 1 NC_004431.1 Residues 1 to 327 of 327 are 84.09 pct identical to residues 1 to 327 of 327 from GenPept.129 : >gb|AAL22043.1| (AE008845) dicarboxylate-binding periplasmic protein [Salmonella typhimurium LT2]; c4-dicarboxylate transport system binding protein 3588676 1039816 c3754 Escherichia coli CFT073 c4-dicarboxylate transport system binding protein NP_755625.1 3587693 D 199310 CDS NP_755626.1 26249586 1039817 3588718..3589200 1 NC_004431.1 Residues 1 to 158 of 160 are 78.48 pct identical to residues 1 to 158 of 160 from GenPept.129 : >gb|AAL22044.1| (AE008845) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 3589200 1039817 c3755 Escherichia coli CFT073 hypothetical protein NP_755626.1 3588718 D 199310 CDS NP_755627.1 26249587 1039818 3589169..3590515 1 NC_004431.1 Residues 15 to 447 of 448 are 89.83 pct identical to residues 1 to 433 of 435 from SwissProt.40 : >sp|P40800|YGIK_SALTY Hypothetical 46.1 kDa protein in PLSC 3'region; c4-dicarboxylate permease 3590515 ygiK 1039818 ygiK Escherichia coli CFT073 c4-dicarboxylate permease NP_755627.1 3589169 D 199310 CDS NP_755628.1 26249588 1039819 complement(3590586..3591998) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3017; Escherichia coli O157:H7 ortholog: z4371; repressor protein for FtsI 3591998 sufI 1039819 sufI Escherichia coli CFT073 repressor protein for FtsI NP_755628.1 3590586 R 199310 CDS NP_755629.1 26249589 1039820 complement(3592073..3592810) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3018; Escherichia coli O157:H7 ortholog: z4372; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3592810 plsC 1039820 plsC Escherichia coli CFT073 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_755629.1 3592073 R 199310 CDS NP_755630.1 26249590 1039822 complement(3592859..3593014) 1 NC_004431.1 hypothetical protein 3593014 1039822 c3759 Escherichia coli CFT073 hypothetical protein NP_755630.1 3592859 R 199310 CDS NP_755631.1 26249591 1039823 complement(3593045..3595303) 1 NC_004431.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3595303 parC 1039823 parC Escherichia coli CFT073 DNA topoisomerase IV subunit A NP_755631.1 3593045 R 199310 CDS NP_755632.1 26249592 1039876 complement(3595441..3597111) 1 NC_004431.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein 3597111 1039876 c3761 Escherichia coli CFT073 binding protein NP_755632.1 3595441 R 199310 CDS NP_755633.1 26249593 1039900 complement(3597157..3597639) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3023; Escherichia coli O157:H7 ortholog: z4375; hypothetical protein 3597639 ygiV 1039900 ygiV Escherichia coli CFT073 hypothetical protein NP_755633.1 3597157 R 199310 CDS NP_755634.1 26249594 1039901 complement(3597692..3598141) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3024; Escherichia coli O157:H7 ortholog: z4376; hypothetical protein 3598141 ygiW 1039901 ygiW Escherichia coli CFT073 hypothetical protein NP_755634.1 3597692 R 199310 CDS NP_755635.1 26249595 1039902 3598236..3598895 1 NC_004431.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3598895 ygiX 1039902 ygiX Escherichia coli CFT073 DNA-binding transcriptional regulator QseB NP_755635.1 3598236 D 199310 CDS NP_755636.1 26249596 1039904 3598892..3600241 1 NC_004431.1 Escherichia coli K-12 ortholog: b3026; Escherichia coli O157:H7 ortholog: z4378; sensor protein QseC 3600241 ygiY 1039904 ygiY Escherichia coli CFT073 sensor protein QseC NP_755636.1 3598892 D 199310 CDS NP_755637.1 26249597 1039905 complement(3600626..3601363) 1 NC_004431.1 hypothetical protein 3601363 1039905 c3766 Escherichia coli CFT073 hypothetical protein NP_755637.1 3600626 R 199310 CDS NP_755638.1 26249598 1039906 complement(3601339..3601818) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z0248; hypothetical protein 3601818 1039906 c3767 Escherichia coli CFT073 hypothetical protein NP_755638.1 3601339 R 199310 CDS NP_755639.1 26249599 1039908 3602068..3602649 1 NC_004431.1 Escherichia coli K-12 ortholog: b3028; Escherichia coli O157:H7 ortholog: z4379; modulator of drug activity B 3602649 mdaB 1039908 mdaB Escherichia coli CFT073 modulator of drug activity B NP_755639.1 3602068 D 199310 CDS NP_755640.1 26249600 1039909 3602680..3602994 1 NC_004431.1 Escherichia coli K-12 ortholog: b3029; Escherichia coli O157:H7 ortholog: z4380; hypothetical protein 3602994 ygiN 1039909 ygiN Escherichia coli CFT073 hypothetical protein NP_755640.1 3602680 D 199310 CDS NP_755641.1 26249601 1039910 complement(3603039..3603926) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4381; hypothetical protein 3603926 1039910 c3770 Escherichia coli CFT073 hypothetical protein NP_755641.1 3603039 R 199310 CDS NP_755642.1 26249602 1039911 complement(3603923..3604933) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4382; iron ABC transporter substrate-binding protein 3604933 1039911 c3771 Escherichia coli CFT073 iron ABC transporter substrate-binding protein NP_755642.1 3603923 R 199310 CDS NP_755643.1 26249603 1039912 complement(3604881..3605930) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4383; iron ABC transporter permease 3605930 1039912 c3772 Escherichia coli CFT073 iron ABC transporter permease NP_755643.1 3604881 R 199310 CDS NP_755644.1 26249604 1039913 complement(3605927..3606910) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4384; iron ABC transporter permease 3606910 1039913 c3773 Escherichia coli CFT073 iron ABC transporter permease NP_755644.1 3605927 R 199310 CDS NP_755645.1 26249605 1039914 complement(3606907..3607716) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0588; Escherichia coli O157:H7 ortholog: z4385; ferric enterobactin transport ATP-binding protein fepC 3607716 1039914 c3774 Escherichia coli CFT073 ferric enterobactin transport ATP-binding protein fepC NP_755645.1 3606907 R 199310 CDS NP_755646.1 26249606 1039915 3608090..3610231 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4386; iron compound receptor 3610231 1039915 c3775 Escherichia coli CFT073 iron compound receptor NP_755646.1 3608090 D 199310 CDS NP_755647.1 26249607 1039916 complement(3610295..3612187) 1 NC_004431.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3612187 parE 1039916 parE Escherichia coli CFT073 DNA topoisomerase IV subunit B NP_755647.1 3610295 R 199310 CDS NP_755648.1 26249608 1039917 complement(3612216..3612797) 1 NC_004431.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 3612797 yqiA 1039917 yqiA Escherichia coli CFT073 esterase NP_755648.1 3612216 R 199310 CDS NP_755649.1 26249609 1039918 complement(3612797..3613624) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3032; Escherichia coli O157:H7 ortholog: z4389; cyclic 3',5'-adenosine monophosphate phosphodiesterase 3613624 icc 1039918 icc Escherichia coli CFT073 cyclic 3',5'-adenosine monophosphate phosphodiesterase NP_755649.1 3612797 R 199310 CDS NP_755650.1 26249610 1039919 complement(3613649..3614071) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3033; Escherichia coli O157:H7 ortholog: z4390; hypothetical protein 3614071 yqiB 1039919 yqiB Escherichia coli CFT073 hypothetical protein NP_755650.1 3613649 R 199310 CDS NP_755651.1 26249611 1039920 complement(3614072..3614701) 1 NC_004431.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 3614701 nudF 1039920 nudF Escherichia coli CFT073 ADP-ribose pyrophosphatase NP_755651.1 3614072 R 199310 CDS NP_755652.2 161486121 1039921 3614906..3616387 1 NC_004431.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3616387 tolC 1039921 tolC Escherichia coli CFT073 outer membrane channel protein NP_755652.2 3614906 D 199310 CDS NP_755653.1 26249613 1039922 3616387..3616647 1 NC_004431.1 Escherichia coli K-12 ortholog: b3036; Escherichia coli O157:H7 ortholog: z4393; hypothetical protein 3616647 ygiA 1039922 ygiA Escherichia coli CFT073 hypothetical protein NP_755653.1 3616387 D 199310 CDS NP_755654.2 161486120 1039923 3616535..3617206 1 NC_004431.1 Escherichia coli K-12 ortholog: b3037; Escherichia coli O157:H7 ortholog: z4394; hypothetical protein 3617206 ygiB 1039923 ygiB Escherichia coli CFT073 hypothetical protein NP_755654.2 3616535 D 199310 CDS NP_755655.1 26249615 1039924 3617212..3618372 1 NC_004431.1 Escherichia coli K-12 ortholog: b3038; Escherichia coli O157:H7 ortholog: z4395; hypothetical protein 3618372 ygiC 1039924 ygiC Escherichia coli CFT073 hypothetical protein NP_755655.1 3617212 D 199310 CDS NP_755656.1 26249616 1039925 3618857..3620653 1 NC_004431.1 Residues 1 to 598 of 598 are 100.00 pct identical to residues 1 to 598 of 598 from GenPept.129 : >gb|AAB49808.1| (U32616) Klebsiella sp. arylsulfate sulfotransferase; arylsulfate sulfotransferase 3620653 asst 1039925 asst Escherichia coli CFT073 arylsulfate sulfotransferase NP_755656.1 3618857 D 199310 CDS NP_755657.1 26249617 1039926 3620671..3621339 1 NC_004431.1 Residues 1 to 222 of 222 are 100.00 pct identical to residues 1 to 222 of 222 from SwissProt.40 : >sp|P97037|DSBA_KLEPN Thiol:disulfide interchange protein dsbA precursor; disulfide isomerase 3621339 1039926 c3786 Escherichia coli CFT073 disulfide isomerase NP_755657.1 3620671 D 199310 CDS NP_755658.1 26249618 1039927 3621354..3622025 1 NC_004431.1 Residues 3 to 223 of 223 are 87.33 pct identical to residues 4 to 224 of 225 from GenPept.129 : >gb|AAL22068.1| (AE008846) disulfide isomerase [Salmonella typhimurium LT2]; disulfide oxidoreductase 3622025 1039927 c3787 Escherichia coli CFT073 disulfide oxidoreductase NP_755658.1 3621354 D 199310 CDS NP_755659.1 26249619 1039928 complement(3622071..3622886) 1 NC_004431.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3622886 ygiD 1039928 ygiD Escherichia coli CFT073 hypothetical protein NP_755659.1 3622071 R 199310 CDS NP_755660.1 26249620 1039929 3622960..3623775 1 NC_004431.1 Escherichia coli K-12 ortholog: b3040; Escherichia coli O157:H7 ortholog: z4397; zinc transporter ZupT 3623775 ygiE 1039929 ygiE Escherichia coli CFT073 zinc transporter ZupT NP_755660.1 3622960 D 199310 CDS NP_755661.1 26249621 1039930 complement(3623837..3624022) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4398; hypothetical protein 3624022 1039930 c3790 Escherichia coli CFT073 hypothetical protein NP_755661.1 3623837 R 199310 CDS NP_755662.1 26249622 1039931 3624578..3625141 1 NC_004431.1 Escherichia coli K-12 ortholog: b3043; Escherichia coli O157:H7 ortholog: z0872; fimbrial protein 3625141 ygiL 1039931 ygiL Escherichia coli CFT073 fimbrial protein NP_755662.1 3624578 D 199310 CDS NP_755663.1 26249623 1039932 3625228..3627750 1 NC_004431.1 Escherichia coli K-12 ortholog: b3046; Escherichia coli O157:H7 ortholog: z0871; outer membrane usher protein yqiG 3627750 yqiG 1039932 yqiG Escherichia coli CFT073 outer membrane usher protein yqiG NP_755663.1 3625228 D 199310 CDS NP_755664.1 26249624 1039936 3627757..3628506 1 NC_004431.1 Escherichia coli K-12 ortholog: b3047; Escherichia coli O157:H7 ortholog: z0869; fimbrial chaperone yqiH 3628506 yqiH 1039936 yqiH Escherichia coli CFT073 fimbrial chaperone yqiH NP_755664.1 3627757 D 199310 CDS NP_755665.1 26249625 1039938 3628503..3629552 1 NC_004431.1 Residues 7 to 349 of 349 are 37.92 pct identical to residues 8 to 353 of 353 from GenPept.129 : >gb|AAG55039.1|AE005249_10 (AE005249) ybgO gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 3629552 1039938 c3794 Escherichia coli CFT073 hypothetical protein NP_755665.1 3628503 D 199310 CDS NP_755666.1 26249626 1039939 complement(3629606..3630259) 1 NC_004431.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3630259 ribB 1039939 ribB Escherichia coli CFT073 3,4-dihydroxy-2-butanone 4-phosphate synthase NP_755666.1 3629606 R 199310 CDS NP_755667.1 26249627 1039940 3630573..3630932 1 NC_004431.1 Escherichia coli K-12 ortholog: b3042; Escherichia coli O157:H7 ortholog: z4400; hypothetical protein 3630932 yqiC 1039940 yqiC Escherichia coli CFT073 hypothetical protein NP_755667.1 3630573 D 199310 CDS NP_755668.1 26249628 1039942 complement(3630967..3631173) 1 NC_004431.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3631173 glgS 1039942 glgS Escherichia coli CFT073 glycogen synthesis protein GlgS NP_755668.1 3630967 R 199310 CDS NP_755669.1 26249629 1039943 3631437..3632066 1 NC_004431.1 Escherichia coli K-12 ortholog: b3050; Escherichia coli O157:H7 ortholog: z4402; hypothetical protein 3632066 yqiJ 1039943 yqiJ Escherichia coli CFT073 hypothetical protein NP_755669.1 3631437 D 199310 CDS NP_755670.1 26249630 1039944 3632093..3633754 1 NC_004431.1 Escherichia coli K-12 ortholog: b3051; Escherichia coli O157:H7 ortholog: z4403; hypothetical protein 3633754 yqiK 1039944 yqiK Escherichia coli CFT073 hypothetical protein NP_755670.1 3632093 D 199310 CDS NP_755671.1 26249631 1039945 complement(3634173..3635606) 1 NC_004431.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3635606 1039945 c3800 Escherichia coli CFT073 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase NP_755671.1 3634173 R 199310 CDS NP_755672.2 161486119 1039946 complement(3635654..3638494) 1 NC_004431.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3638494 glnE 1039946 glnE Escherichia coli CFT073 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase NP_755672.2 3635654 R 199310 CDS NP_755673.1 26249633 1039947 complement(3638517..3639845) 1 NC_004431.1 ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407; hypothetical protein 3639845 ygiF 1039947 ygiF Escherichia coli CFT073 hypothetical protein NP_755673.1 3638517 R 199310 CDS NP_755674.1 26249634 1039948 complement(3639888..3640340) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5815; transposase 3640340 1039948 c3803 Escherichia coli CFT073 transposase NP_755674.1 3639888 R 199310 CDS NP_755675.1 26249635 1039951 3640353..3641558 1 NC_004431.1 Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664; hypothetical protein 3641558 ydcM 1039951 ydcM Escherichia coli CFT073 hypothetical protein NP_755675.1 3640353 D 199310 CDS NP_755676.1 26249636 1039952 3641901..3642521 1 NC_004431.1 Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408; signal transduction protein 3642521 ygiM 1039952 ygiM Escherichia coli CFT073 signal transduction protein NP_755676.1 3641901 D 199310 CDS NP_755677.1 26249637 1039953 3642585..3643823 1 NC_004431.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3643823 cca 1039953 cca Escherichia coli CFT073 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase NP_755677.1 3642585 D 199310 CDS NP_755678.1 26249638 1039954 complement(3643903..3644727) 1 NC_004431.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3644727 uppP 1039954 uppP Escherichia coli CFT073 undecaprenyl pyrophosphate phosphatase NP_755678.1 3643903 R 199310 CDS NP_755679.1 26249639 1039956 complement(3644815..3645186) 1 NC_004431.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3645186 folB 1039956 folB Escherichia coli CFT073 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase NP_755679.1 3644815 R 199310 CDS NP_755680.1 26249640 1039957 3645288..3645905 1 NC_004431.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3645905 ygiH 1039957 ygiH Escherichia coli CFT073 glycerol-3-phosphate acyltransferase PlsY NP_755680.1 3645288 D 199310 CDS NP_755681.1 26249641 1039958 complement(3645918..3646898) 1 NC_004431.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3646898 ygiP 1039958 ygiP Escherichia coli CFT073 transcriptional activator TtdR NP_755681.1 3645918 R 199310 CDS NP_755682.1 26249642 1039960 3646881..3647003 1 NC_004431.1 hypothetical protein 3647003 1039960 c3811 Escherichia coli CFT073 hypothetical protein NP_755682.1 3646881 D 199310 CDS NP_755683.1 26249643 1039961 3647057..3647968 1 NC_004431.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3647968 ttdA 1039961 ttdA Escherichia coli CFT073 tartrate dehydratase subunit alpha NP_755683.1 3647057 D 199310 CDS NP_755684.1 26249644 1039963 3647965..3648570 1 NC_004431.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3648570 ttdB 1039963 ttdB Escherichia coli CFT073 L(+)-tartrate dehydratase subunit beta NP_755684.1 3647965 D 199310 CDS NP_755685.1 26249645 1039964 3648618..3650081 1 NC_004431.1 Escherichia coli K-12 ortholog: b3063; Escherichia coli O157:H7 ortholog: z4416; tartrate carrier/transporter 3650081 ygjE 1039964 ygjE Escherichia coli CFT073 tartrate carrier/transporter NP_755685.1 3648618 D 199310 CDS NP_755686.1 26249646 1039965 complement(3650124..3651137) 1 NC_004431.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3651137 ygjD 1039965 ygjD Escherichia coli CFT073 DNA-binding/iron metalloprotein/AP endonuclease NP_755686.1 3650124 R 199310 CDS NP_755687.1 26249647 1039967 3651375..3651590 1 NC_004431.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3651590 rpsU 1039967 rpsU Escherichia coli CFT073 30S ribosomal protein S21 NP_755687.1 3651375 D 199310 CDS NP_755688.1 26249648 1039969 3651701..3653446 1 NC_004431.1 synthesizes RNA primers at the replication forks; DNA primase 3653446 dnaG 1039969 dnaG Escherichia coli CFT073 DNA primase NP_755688.1 3651701 D 199310 CDS NP_755689.1 26249649 1039971 3653460..3653582 1 NC_004431.1 hypothetical protein 3653582 1039971 c3818 Escherichia coli CFT073 hypothetical protein NP_755689.1 3653460 D 199310 CDS NP_755690.1 26249650 1039973 3653641..3654747 1 NC_004431.1 Residues 1 to 313 of 319 are 89.00 pct identical to residues 51 to 363 of 613 from MG1655 : b3067; hypothetical protein 3654747 1039973 c3819 Escherichia coli CFT073 hypothetical protein NP_755690.1 3653641 D 199310 CDS NP_755691.1 26249651 1039974 complement(3654441..3655538) 1 NC_004431.1 hypothetical protein 3655538 1039974 c3820 Escherichia coli CFT073 hypothetical protein NP_755691.1 3654441 R 199310 CDS NP_755692.1 26249652 1039975 3654744..3655484 1 NC_004431.1 Polymerase sigma factor; Residues 2 to 246 of 246 are 99.59 pct identical to residues 416 to 660 of 660 from GenPept.129 : >gb|AAL22085.1| (AE008847) sigma D (sigma 70) factor of RNA polymerase, major sigma factor during exponential growth [Salmonella typhimurium LT2]; RpoD protein 3655484 rpoD 1039975 rpoD Escherichia coli CFT073 RpoD protein NP_755692.1 3654744 D 199310 CDS NP_755693.1 26249653 1039976 complement(3655562..3656068) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3068; Escherichia coli O157:H7 ortholog: z4421; G/U mismatch-specific DNA glycosylase 3656068 ygjF 1039976 ygjF Escherichia coli CFT073 G/U mismatch-specific DNA glycosylase NP_755693.1 3655562 R 199310 CDS NP_755694.1 26249654 1039979 complement(3656322..3657101) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3070; Escherichia coli O157:H7 ortholog: z4423; hypothetical protein 3657101 yqjH 1039979 yqjH Escherichia coli CFT073 hypothetical protein NP_755694.1 3656322 R 199310 CDS NP_755695.1 26249655 1039981 3657374..3657997 1 NC_004431.1 Escherichia coli K-12 ortholog: b3071; Escherichia coli O157:H7 ortholog: z4424; hypothetical protein 3657997 yqjI 1039981 yqjI Escherichia coli CFT073 hypothetical protein NP_755695.1 3657374 D 199310 CDS NP_755696.1 26249656 1039983 complement(3658151..3659671) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3072; Escherichia coli O157:H7 ortholog: z4425; aerotaxis receptor 3659671 aer 1039983 aer Escherichia coli CFT073 aerotaxis receptor NP_755696.1 3658151 R 199310 CDS NP_755697.1 26249657 1039984 complement(3659862..3659990) 1 NC_004431.1 hypothetical protein 3659990 1039984 c3826 Escherichia coli CFT073 hypothetical protein NP_755697.1 3659862 R 199310 CDS NP_755698.1 26249658 1039985 3659947..3660153 1 NC_004431.1 hypothetical protein 3660153 1039985 c3827 Escherichia coli CFT073 hypothetical protein NP_755698.1 3659947 D 199310 CDS NP_755699.2 161486118 1039986 3660062..3661468 1 NC_004431.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3661468 ygjG 1039986 ygjG Escherichia coli CFT073 putrescine--2-oxoglutarate aminotransferase NP_755699.2 3660062 D 199310 CDS NP_755700.1 26249660 1039987 3661452..3661862 1 NC_004431.1 hypothetical protein 3661862 1039987 c3829 Escherichia coli CFT073 hypothetical protein NP_755700.1 3661452 D 199310 CDS NP_755701.1 26249661 1039988 complement(3661510..3661842) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3074; Escherichia coli O157:H7 ortholog: z4427; hypothetical protein 3661842 ygjH 1039988 ygjH Escherichia coli CFT073 hypothetical protein NP_755701.1 3661510 R 199310 CDS NP_755702.1 26249662 1039989 3661949..3662131 1 NC_004431.1 hypothetical protein 3662131 1039989 c3831 Escherichia coli CFT073 hypothetical protein NP_755702.1 3661949 D 199310 CDS NP_755703.1 26249663 1039992 3662061..3663044 1 NC_004431.1 Escherichia coli K-12 ortholog: b3075; Escherichia coli O157:H7 ortholog: z4428; DNA-binding transcriptional repressor EbgR 3663044 ebgR 1039992 ebgR Escherichia coli CFT073 DNA-binding transcriptional repressor EbgR NP_755703.1 3662061 D 199310 CDS NP_755704.2 161486117 1039993 3663228..3666320 1 NC_004431.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3666320 ebgA 1039993 ebgA Escherichia coli CFT073 cryptic beta-D-galactosidase subunit alpha NP_755704.2 3663228 D 199310 CDS NP_755705.1 26249665 1039995 3666317..3666766 1 NC_004431.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3666766 ebgC 1039995 ebgC Escherichia coli CFT073 cryptic beta-D-galactosidase subunit beta NP_755705.1 3666317 D 199310 CDS NP_755706.1 26249666 1039996 complement(3666617..3666757) 1 NC_004431.1 hypothetical protein 3666757 1039996 c3835 Escherichia coli CFT073 hypothetical protein NP_755706.1 3666617 R 199310 CDS NP_755707.1 26249667 1039997 3666829..3668262 1 NC_004431.1 Escherichia coli K-12 ortholog: b3078; Escherichia coli O157:H7 ortholog: z4431; transporter YgjI 3668262 ygjI 1039997 ygjI Escherichia coli CFT073 transporter YgjI NP_755707.1 3666829 D 199310 CDS NP_755708.1 26249668 1040000 3668396..3669466 1 NC_004431.1 Escherichia coli K-12 ortholog: b3079; Escherichia coli O157:H7 ortholog: z4432; hypothetical protein 3669466 ygjJ 1040000 ygjJ Escherichia coli CFT073 hypothetical protein NP_755708.1 3668396 D 199310 CDS NP_755709.1 26249669 1040001 3669483..3671834 1 NC_004431.1 Escherichia coli K-12 ortholog: b3080; Escherichia coli O157:H7 ortholog: z4433; glycosyl hydrolase 3671834 ygjK 1040001 ygjK Escherichia coli CFT073 glycosyl hydrolase NP_755709.1 3669483 D 199310 CDS NP_755710.1 26249670 1040002 3672060..3674078 1 NC_004431.1 NADPH; Escherichia coli K-12 ortholog: b3081; Escherichia coli O157:H7 ortholog: z4434; 2,4-dienoyl-CoA reductase 3674078 ygjL 1040002 ygjL Escherichia coli CFT073 2,4-dienoyl-CoA reductase NP_755710.1 3672060 D 199310 CDS NP_755711.1 26249671 1040003 complement(3674123..3674539) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3082; Escherichia coli O157:H7 ortholog: z4435; hypothetical protein 3674539 1040003 c3840 Escherichia coli CFT073 hypothetical protein NP_755711.1 3674123 R 199310 CDS NP_755712.1 26249672 1040004 complement(3674536..3674706) 1 NC_004431.1 Residues 32 to 56 of 56 are 100.00 pct identical to residues 80 to 104 of 104 from GenPept.129 : >gb|AAG58216.1|AE005538_3 (AE005538) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 3674706 1040004 c3841 Escherichia coli CFT073 hypothetical protein NP_755712.1 3674536 R 199310 CDS NP_755713.1 26249673 1040005 complement(3674810..3675946) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3084; Escherichia coli O157:H7 ortholog: z4437; ribosomal RNA small subunit methyltransferase D 3675946 ygjO 1040005 ygjO Escherichia coli CFT073 ribosomal RNA small subunit methyltransferase D NP_755713.1 3674810 R 199310 CDS NP_755714.1 26249674 1040008 3675995..3676534 1 NC_004431.1 Escherichia coli K-12 ortholog: b3085; Escherichia coli O157:H7 ortholog: z4438; hypothetical protein 3676534 ygjP 1040008 ygjP Escherichia coli CFT073 hypothetical protein NP_755714.1 3675995 D 199310 CDS NP_755715.1 26249675 1040009 3676602..3677303 1 NC_004431.1 Escherichia coli K-12 ortholog: b3086; Escherichia coli O157:H7 ortholog: z4439; hypothetical protein 3677303 ygjQ 1040009 ygjQ Escherichia coli CFT073 hypothetical protein NP_755715.1 3676602 D 199310 CDS NP_755716.1 26249676 1040010 3677364..3678368 1 NC_004431.1 Escherichia coli K-12 ortholog: b3087; Escherichia coli O157:H7 ortholog: z4440; oxidoreductase ygjR 3678368 ygjR 1040010 ygjR Escherichia coli CFT073 oxidoreductase ygjR NP_755716.1 3677364 D 199310 CDS NP_755717.1 26249677 1040011 3678652..3679617 1 NC_004431.1 Escherichia coli K-12 ortholog: b3088; Escherichia coli O157:H7 ortholog: z4441; hypothetical protein 3679617 ygjT 1040011 ygjT Escherichia coli CFT073 hypothetical protein NP_755717.1 3678652 D 199310 CDS NP_755718.1 26249678 1040012 3679941..3681185 1 NC_004431.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3681185 ygjU 1040012 ygjU Escherichia coli CFT073 serine/threonine transporter SstT NP_755718.1 3679941 D 199310 CDS NP_755719.1 26249679 1040014 complement(3681189..3681740) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3090; Escherichia coli O157:H7 ortholog: z4443; hypothetical protein 3681740 ygjV 1040014 ygjV Escherichia coli CFT073 hypothetical protein NP_755719.1 3681189 R 199310 CDS NP_755720.1 26249680 1040015 complement(3681823..3683310) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3091; Escherichia coli O157:H7 ortholog: z4444; altronate hydrolase 3683310 uxaA 1040015 uxaA Escherichia coli CFT073 altronate hydrolase NP_755720.1 3681823 R 199310 CDS NP_755721.2 161486116 1040016 complement(3683325..3684737) 1 NC_004431.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3684737 uxaC 1040016 uxaC Escherichia coli CFT073 glucuronate isomerase NP_755721.2 3683325 R 199310 CDS NP_755722.1 26249682 1040017 3685100..3686518 1 NC_004431.1 Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter 3686518 exuT 1040017 exuT Escherichia coli CFT073 hexuronate transporter NP_755722.1 3685100 D 199310 CDS NP_755723.2 161486115 1040018 3686648..3687424 1 NC_004431.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3687424 exuR 1040018 exuR Escherichia coli CFT073 DNA-binding transcriptional repressor ExuR NP_755723.2 3686648 D 199310 CDS NP_755724.1 26249684 1040019 3687769..3688431 1 NC_004431.1 Escherichia coli K-12 ortholog: b3095; Escherichia coli O157:H7 ortholog: z4449; hypothetical protein 3688431 yqjA 1040019 yqjA Escherichia coli CFT073 hypothetical protein NP_755724.1 3687769 D 199310 CDS NP_755725.1 26249685 1040041 3688435..3688818 1 NC_004431.1 Escherichia coli K-12 ortholog: b3096; Escherichia coli O157:H7 ortholog: z4450; hypothetical protein 3688818 yqjB 1040041 yqjB Escherichia coli CFT073 hypothetical protein NP_755725.1 3688435 D 199310 CDS NP_755726.3 347357883 1040047 3688950..3689333 1 NC_004431.1 Escherichia coli K-12 ortholog: b3097; Escherichia coli O157:H7 ortholog: z4451; hypothetical protein 3689333 yqjC 1040047 yqjC Escherichia coli CFT073 hypothetical protein NP_755726.3 3688950 D 199310 CDS NP_755727.1 26249687 1040049 3689371..3689676 1 NC_004431.1 Escherichia coli K-12 ortholog: b3098; Escherichia coli O157:H7 ortholog: z4452; hypothetical protein 3689676 yqjD 1040049 yqjD Escherichia coli CFT073 hypothetical protein NP_755727.1 3689371 D 199310 CDS NP_755728.1 26249688 1040059 3689679..3690083 1 NC_004431.1 Escherichia coli K-12 ortholog: b3099; Escherichia coli O157:H7 ortholog: z4453; hypothetical protein 3690083 yqjE 1040059 yqjE Escherichia coli CFT073 hypothetical protein NP_755728.1 3689679 D 199310 CDS NP_755729.1 26249689 1040061 3690073..3690372 1 NC_004431.1 Escherichia coli K-12 ortholog: b3100; Escherichia coli O157:H7 ortholog: z4454; hypothetical protein 3690372 yqjK 1040061 yqjK Escherichia coli CFT073 hypothetical protein NP_755729.1 3690073 D 199310 CDS NP_755730.1 26249690 1040067 3690546..3690950 1 NC_004431.1 Escherichia coli K-12 ortholog: b3101; Escherichia coli O157:H7 ortholog: z4455; hypothetical protein 3690950 yqjF 1040067 yqjF Escherichia coli CFT073 hypothetical protein NP_755730.1 3690546 D 199310 CDS NP_755731.1 26249691 1040077 3692270..3692659 1 NC_004431.1 Escherichia coli K-12 ortholog: b3103; Escherichia coli O157:H7 ortholog: z4457; hypothetical protein 3692659 yhaH 1040077 yhaH Escherichia coli CFT073 hypothetical protein NP_755731.1 3692270 D 199310 CDS NP_755732.1 26249692 1040078 complement(3692693..3693589) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3105; Escherichia coli O157:H7 ortholog: z4459; transcriptional regulator YhaJ 3693589 yhaJ 1040078 yhaJ Escherichia coli CFT073 transcriptional regulator YhaJ NP_755732.1 3692693 R 199310 CDS NP_755733.1 26249693 1040080 3693694..3694395 1 NC_004431.1 Escherichia coli K-12 ortholog: b3106; Escherichia coli O157:H7 ortholog: z4460; hypothetical protein 3694395 yhaK 1040080 yhaK Escherichia coli CFT073 hypothetical protein NP_755733.1 3693694 D 199310 CDS NP_755734.1 26249694 1040082 complement(3694153..3694281) 1 NC_004431.1 hypothetical protein 3694281 1040082 c3865 Escherichia coli CFT073 hypothetical protein NP_755734.1 3694153 R 199310 CDS NP_755735.1 26249695 1040084 3694412..3694582 1 NC_004431.1 Escherichia coli K-12 ortholog: b3107; Escherichia coli O157:H7 ortholog: z4461; hypothetical protein 3694582 yhaL 1040084 yhaL Escherichia coli CFT073 hypothetical protein NP_755735.1 3694412 D 199310 CDS NP_755736.1 26249696 1040085 complement(3694716..3696026) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4462; hypothetical protein 3696026 1040085 c3867 Escherichia coli CFT073 hypothetical protein NP_755736.1 3694716 R 199310 CDS NP_755737.1 26249697 1040095 complement(3697665..3699035) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1814; Escherichia coli O157:H7 ortholog: z4464; L-serine dehydratase 1 3699035 1040095 c3870 Escherichia coli CFT073 L-serine dehydratase 1 NP_755737.1 3697665 R 199310 CDS NP_755738.1 26249698 1040096 complement(3699101..3699553) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3113; Escherichia coli O157:H7 ortholog: z4465; hypothetical protein 3699553 yhaR 1040096 yhaR Escherichia coli CFT073 hypothetical protein NP_755738.1 3699101 R 199310 CDS NP_755739.1 26249699 1040101 complement(3699504..3701798) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3114; Escherichia coli O157:H7 ortholog: z4466; keto-acid formate acetyltransferase 3701798 tdcE 1040101 tdcE Escherichia coli CFT073 keto-acid formate acetyltransferase NP_755739.1 3699504 R 199310 CDS NP_755740.1 26249700 1040103 complement(3701832..3701984) 1 NC_004431.1 Residues 1 to 50 of 50 are 98.00 pct identical to residues 357 to 406 of 406 from MG1655 : b3115; hypothetical protein 3701984 1040103 c3873 Escherichia coli CFT073 hypothetical protein NP_755740.1 3701832 R 199310 CDS NP_755741.1 26249701 1040107 complement(3703066..3704397) 1 NC_004431.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3704397 tdcC 1040107 tdcC Escherichia coli CFT073 threonine/serine transporter TdcC NP_755741.1 3703066 R 199310 CDS NP_755742.1 26249702 1040111 complement(3704419..3705408) 1 NC_004431.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3705408 tdcB 1040111 tdcB Escherichia coli CFT073 threonine dehydratase NP_755742.1 3704419 R 199310 CDS NP_755743.1 26249703 1040114 complement(3705507..3706445) 1 NC_004431.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3706445 tdcA 1040114 tdcA Escherichia coli CFT073 DNA-binding transcriptional activator TdcA NP_755743.1 3705507 R 199310 CDS NP_755744.3 347357882 1040115 3706622..3706978 1 NC_004431.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3706978 tdcR 1040115 tdcR Escherichia coli CFT073 DNA-binding transcriptional activator TdcR NP_755744.3 3706622 D 199310 CDS NP_755745.1 26249705 1040120 3707204..3707332 1 NC_004431.1 Residues 4 to 41 of 42 are 87.80 pct identical to residues 1 to 41 of 186 from GenPept.129 : >emb|CAC50646.1| (AX188965) unnamed protein product [Escherichia coli]; hypothetical protein 3707332 1040120 c3878 Escherichia coli CFT073 hypothetical protein NP_755745.1 3707204 D 199310 CDS NP_755746.2 161486113 1040121 complement(3707944..3709089) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3124; Escherichia coli O157:H7 ortholog: z4476; glycerate kinase I 3709089 yhaD 1040121 yhaD Escherichia coli CFT073 glycerate kinase I NP_755746.2 3707944 R 199310 CDS NP_755747.2 161486112 1040122 complement(3709186..3710076) 1 NC_004431.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3710076 garR 1040122 garR Escherichia coli CFT073 tartronate semialdehyde reductase NP_755747.2 3709186 R 199310 CDS NP_755748.1 26249708 1040124 complement(3710106..3710876) 1 NC_004431.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3710876 yhaF 1040124 yhaF Escherichia coli CFT073 alpha-dehydro-beta-deoxy-D-glucarate aldolase NP_755748.1 3710106 R 199310 CDS NP_755749.1 26249709 1040127 complement(3710892..3712226) 1 NC_004431.1 D-galactarate permease; Escherichia coli K-12 ortholog: b3127; Escherichia coli O157:H7 ortholog: z4479; galactarate transporter 3712226 yhaU 1040127 yhaU Escherichia coli CFT073 galactarate transporter NP_755749.1 3710892 R 199310 CDS NP_755750.1 26249710 1040129 3712601..3714172 1 NC_004431.1 Escherichia coli K-12 ortholog: b3128; Escherichia coli O157:H7 ortholog: z4480; D-galactarate dehydratase 3714172 yhaG 1040129 yhaG Escherichia coli CFT073 D-galactarate dehydratase NP_755750.1 3712601 D 199310 CDS NP_755751.1 26249711 1040131 3714321..3714656 1 NC_004431.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3714656 sohA 1040131 sohA Escherichia coli CFT073 regulator PrlF NP_755751.1 3714321 D 199310 CDS NP_755752.1 26249712 1040132 3714656..3715120 1 NC_004431.1 Escherichia coli K-12 ortholog: b3130; Escherichia coli O157:H7 ortholog: z4482; hypothetical protein 3715120 yhaV 1040132 yhaV Escherichia coli CFT073 hypothetical protein NP_755752.1 3714656 D 199310 CDS NP_755753.1 26249713 1040133 complement(3715175..3715984) 1 NC_004431.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3715984 agaR 1040133 agaR Escherichia coli CFT073 DNA-binding transcriptional regulator AgaR NP_755753.1 3715175 R 199310 CDS NP_755754.1 26249714 1040135 3716233..3717513 1 NC_004431.1 Escherichia coli K-12 ortholog: b3132; Escherichia coli O157:H7 ortholog: z4484; tagatose 6-phosphate kinase agaZ 3717513 agaZ 1040135 agaZ Escherichia coli CFT073 tagatose 6-phosphate kinase agaZ NP_755754.1 3716233 D 199310 CDS NP_755755.1 26249715 1040137 3717500..3718009 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3718009 agaV 1040137 agaV Escherichia coli CFT073 PTS system N-acetylgalactosamine-specific transporter subunit IIB NP_755755.1 3717500 D 199310 CDS NP_755756.1 26249716 1040144 3718020..3718799 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4486; phosphotransferase system enzyme subunit 3718799 1040144 c3889 Escherichia coli CFT073 phosphotransferase system enzyme subunit NP_755756.1 3718020 D 199310 CDS NP_755757.1 26249717 1040146 3718783..3719667 1 NC_004431.1 EIID-AGA; Escherichia coli K-12 ortholog: b3140; Escherichia coli O157:H7 ortholog: z4487; PTS system, N-acetylgalactosamine-specific IID component 3719667 1040146 c3890 Escherichia coli CFT073 PTS system, N-acetylgalactosamine-specific IID component NP_755757.1 3718783 D 199310 CDS NP_755758.1 26249718 1040148 3719685..3720119 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4488; phosphotransferase system enzyme subunit 3720119 1040148 c3891 Escherichia coli CFT073 phosphotransferase system enzyme subunit NP_755758.1 3719685 D 199310 CDS NP_755759.1 26249719 1040150 3720095..3721249 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4489; N-acetylgalctosamine-6-phosphate deacetylase 3721249 1040150 c3892 Escherichia coli CFT073 N-acetylgalctosamine-6-phosphate deacetylase NP_755759.1 3720095 D 199310 CDS NP_755760.1 26249720 1040157 3721598..3722752 1 NC_004431.1 Escherichia coli K-12 ortholog: b3136; Escherichia coli O157:H7 ortholog: z4490; tagatose-6-phosphate ketose/aldose isomerase 3722752 agaS 1040157 agaS Escherichia coli CFT073 tagatose-6-phosphate ketose/aldose isomerase NP_755760.1 3721598 D 199310 CDS NP_755761.1 26249721 1040161 3722765..3723625 1 NC_004431.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3723625 kbaY 1040161 kbaY Escherichia coli CFT073 tagatose-bisphosphate aldolase NP_755761.1 3722765 D 199310 CDS NP_755762.1 26249722 1040162 3723792..3724268 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3724268 agaB 1040162 agaB Escherichia coli CFT073 PTS system N-acetylgalactosamine-specific transporter subunit IIB NP_755762.1 3723792 D 199310 CDS NP_755763.1 26249723 1040163 3724307..3725110 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3725110 agaC 1040163 agaC Escherichia coli CFT073 PTS system N-acetylgalactosamine-specific transporter subunit IIC NP_755763.1 3724307 D 199310 CDS NP_755764.1 26249724 1040165 3725031..3725891 1 NC_004431.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3725891 agaD 1040165 agaD Escherichia coli CFT073 PTS system N-acetylgalactosamine-specific transporter subunit IID NP_755764.1 3725031 D 199310 CDS NP_755765.1 26249725 1040167 3725892..3726659 1 NC_004431.1 Escherichia coli K-12 ortholog: b3141; Escherichia coli O157:H7 ortholog: z4497; galactosamine-6-phosphate isomerase 3726659 agaI 1040167 agaI Escherichia coli CFT073 galactosamine-6-phosphate isomerase NP_755765.1 3725892 D 199310 CDS NP_755766.1 26249726 1040168 complement(3726709..3727572) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3146; Escherichia coli O157:H7 ortholog: z4505; hypothetical protein 3727572 yraL 1040168 yraL Escherichia coli CFT073 hypothetical protein NP_755766.1 3726709 R 199310 CDS NP_755767.1 26249727 1040171 3727512..3729674 1 NC_004431.1 Escherichia coli K-12 ortholog: b3147; Escherichia coli O157:H7 ortholog: z4506; hypothetical protein 3729674 yraM 1040171 yraM Escherichia coli CFT073 hypothetical protein NP_755767.1 3727512 D 199310 CDS NP_755768.1 26249728 1040172 3729632..3730027 1 NC_004431.1 Escherichia coli K-12 ortholog: b3148; Escherichia coli O157:H7 ortholog: z4507; hypothetical protein 3730027 yraN 1040172 yraN Escherichia coli CFT073 hypothetical protein NP_755768.1 3729632 D 199310 CDS NP_755769.1 26249729 1040173 complement(3729896..3730021) 1 NC_004431.1 hypothetical protein 3730021 1040173 c3902 Escherichia coli CFT073 hypothetical protein NP_755769.1 3729896 R 199310 CDS NP_755770.1 26249730 1040174 3730047..3730637 1 NC_004431.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3730637 yraO 1040174 yraO Escherichia coli CFT073 DnaA initiator-associating protein DiaA NP_755770.1 3730047 D 199310 CDS NP_755771.1 26249731 1040176 3730647..3731222 1 NC_004431.1 Escherichia coli K-12 ortholog: b3150; Escherichia coli O157:H7 ortholog: z4509; hypothetical protein 3731222 yraP 1040176 yraP Escherichia coli CFT073 hypothetical protein NP_755771.1 3730647 D 199310 CDS NP_755772.1 26249732 1040177 complement(3731335..3732375) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3151; Escherichia coli O157:H7 ortholog: z4510; hypothetical protein 3732375 yraQ 1040177 yraQ Escherichia coli CFT073 hypothetical protein NP_755772.1 3731335 R 199310 CDS NP_755773.1 26249733 1040179 complement(3732448..3733083) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3152; Escherichia coli O157:H7 ortholog: z4511; hypothetical protein 3733083 yraR 1040179 yraR Escherichia coli CFT073 hypothetical protein NP_755773.1 3732448 R 199310 CDS NP_755774.1 26249734 1040180 complement(3733125..3733547) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3154; Escherichia coli O157:H7 ortholog: z4514; hypothetical protein 3733547 yhbP 1040180 yhbP Escherichia coli CFT073 hypothetical protein NP_755774.1 3733125 R 199310 CDS NP_755775.1 26249735 1040182 3733598..3733900 1 NC_004431.1 Escherichia coli K-12 ortholog: b3155; Escherichia coli O157:H7 ortholog: z4516; GIY-YIG nuclease superfamily protein 3733900 yhbQ 1040182 yhbQ Escherichia coli CFT073 GIY-YIG nuclease superfamily protein NP_755775.1 3733598 D 199310 CDS NP_755776.1 26249736 1040184 complement(3733887..3734390) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3156; Escherichia coli O157:H7 ortholog: z4517; acetyltransferase YhbS 3734390 yhbS 1040184 yhbS Escherichia coli CFT073 acetyltransferase YhbS NP_755776.1 3733887 R 199310 CDS NP_755777.1 26249737 1040187 complement(3734384..3734932) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3157; Escherichia coli O157:H7 ortholog: z4518; hypothetical protein 3734932 yhbT 1040187 yhbT Escherichia coli CFT073 hypothetical protein NP_755777.1 3734384 R 199310 CDS NP_755778.1 26249738 1040193 3735090..3736112 1 NC_004431.1 Escherichia coli K-12 ortholog: b3158; Escherichia coli O157:H7 ortholog: z4519; protease yhbU 3736112 yhbU 1040193 yhbU Escherichia coli CFT073 protease yhbU NP_755778.1 3735090 D 199310 CDS NP_755779.1 26249739 1040195 3736103..3736999 1 NC_004431.1 Escherichia coli K-12 ortholog: b3159; Escherichia coli O157:H7 ortholog: z4520; hypothetical protein 3736999 yhbV 1040195 yhbV Escherichia coli CFT073 hypothetical protein NP_755779.1 3736103 D 199310 CDS NP_755780.1 26249740 1040204 3737080..3738087 1 NC_004431.1 Escherichia coli K-12 ortholog: b3160; Escherichia coli O157:H7 ortholog: z4521; hypothetical protein 3738087 yhbW 1040204 yhbW Escherichia coli CFT073 hypothetical protein NP_755780.1 3737080 D 199310 CDS NP_755781.1 26249741 1040206 complement(3738206..3739450) 1 NC_004431.1 tryptophan transporter of high affinity; tryptophan permease 3739450 mtr 1040206 mtr Escherichia coli CFT073 tryptophan permease NP_755781.1 3738206 R 199310 CDS NP_755782.1 26249742 1040209 3739466..3739603 1 NC_004431.1 hypothetical protein 3739603 1040209 c3915 Escherichia coli CFT073 hypothetical protein NP_755782.1 3739466 D 199310 CDS NP_755783.2 161486111 1040245 complement(3739604..3741493) 1 NC_004431.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3741493 deaD 1040245 deaD Escherichia coli CFT073 ATP-dependent RNA helicase DeaD NP_755783.2 3739604 R 199310 CDS NP_755784.1 26249744 1040248 3741630..3741788 1 NC_004431.1 hypothetical protein 3741788 1040248 c3917 Escherichia coli CFT073 hypothetical protein NP_755784.1 3741630 D 199310 CDS NP_755785.1 26249745 1040250 complement(3741673..3742557) 1 NC_004431.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3742557 yhbM 1040250 yhbM Escherichia coli CFT073 lipoprotein NlpI NP_755785.1 3741673 R 199310 CDS NP_755786.1 26249746 1040251 3742603..3744825 1 NC_004431.1 hypothetical protein 3744825 1040251 c3919 Escherichia coli CFT073 hypothetical protein NP_755786.1 3742603 D 199310 CDS NP_755787.1 26249747 1040255 complement(3742666..3744888) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3164; Escherichia coli O157:H7 ortholog: z4525; polynucleotide phosphorylase 3744888 pnp 1040255 pnp Escherichia coli CFT073 polynucleotide phosphorylase NP_755787.1 3742666 R 199310 CDS NP_755788.1 26249748 1040257 complement(3745048..3745317) 1 NC_004431.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3745317 rpsO 1040257 rpsO Escherichia coli CFT073 30S ribosomal protein S15 NP_755788.1 3745048 R 199310 CDS NP_755789.1 26249749 1040258 complement(3745466..3746410) 1 NC_004431.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3746410 truB 1040258 truB Escherichia coli CFT073 tRNA pseudouridine synthase B NP_755789.1 3745466 R 199310 CDS NP_755790.2 161486110 1040259 complement(3746410..3746811) 1 NC_004431.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3746811 rbfA 1040259 rbfA Escherichia coli CFT073 ribosome-binding factor A NP_755790.2 3746410 R 199310 CDS NP_755791.1 26249751 1040260 complement(3746975..3749647) 1 NC_004431.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3749647 infB 1040260 infB Escherichia coli CFT073 translation initiation factor IF-2 NP_755791.1 3746975 R 199310 CDS NP_755792.1 26249752 1040261 3749504..3750973 1 NC_004431.1 hypothetical protein 3750973 1040261 c3925 Escherichia coli CFT073 hypothetical protein NP_755792.1 3749504 D 199310 CDS NP_755793.1 26249753 1040263 complement(3749672..3751159) 1 NC_004431.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3751159 nusA 1040263 nusA Escherichia coli CFT073 transcription elongation factor NusA NP_755793.1 3749672 R 199310 CDS NP_755794.2 161486109 1040264 complement(3751187..3751639) 1 NC_004431.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3751639 yhbC 1040264 yhbC Escherichia coli CFT073 hypothetical protein NP_755794.2 3751187 R 199310 CDS YP_004853821.1 347357938 1040266 3751822..3752184 1 NC_004431.1 hypothetical protein 3752184 1040266 c3928 Escherichia coli CFT073 hypothetical protein YP_004853821.1 3751822 D 199310 CDS NP_755796.1 26249756 1040269 3752270..3753613 1 NC_004431.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3753613 argG 1040269 argG Escherichia coli CFT073 argininosuccinate synthase NP_755796.1 3752270 D 199310 CDS NP_755797.1 26249757 1040270 complement(3753621..3755279) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3173; Escherichia coli O157:H7 ortholog: z4535; outer-membrane protein yhbX 3755279 yhbX 1040270 yhbX Escherichia coli CFT073 outer-membrane protein yhbX NP_755797.1 3753621 R 199310 CDS NP_755798.2 161486108 1040273 complement(3755804..3756136) 1 NC_004431.1 Preprotein translocase band 1 subunit; Escherichia coli K-12 ortholog: b3175; Escherichia coli O157:H7 ortholog: z4537; preprotein translocase subunit SecG 3756136 secG 1040273 secG Escherichia coli CFT073 preprotein translocase subunit SecG NP_755798.2 3755804 R 199310 CDS NP_755799.1 26249759 1040274 complement(3756364..3757701) 1 NC_004431.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3757701 glmM 1040274 glmM Escherichia coli CFT073 phosphoglucosamine mutase NP_755799.1 3756364 R 199310 CDS NP_755800.2 161486107 1040275 complement(3757694..3758542) 1 NC_004431.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3758542 folP 1040275 folP Escherichia coli CFT073 dihydropteroate synthase NP_755800.2 3757694 R 199310 CDS NP_755801.1 26249761 1040277 3760536..3760670 1 NC_004431.1 hypothetical protein 3760670 1040277 c3935 Escherichia coli CFT073 hypothetical protein NP_755801.1 3760536 D 199310 CDS NP_755802.1 26249762 1040278 complement(3760667..3761296) 1 NC_004431.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 3761296 rrmJ 1040278 rrmJ Escherichia coli CFT073 23S rRNA methyltransferase NP_755802.1 3760667 R 199310 CDS NP_755803.1 26249763 1040279 3761422..3761715 1 NC_004431.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3761715 yhbY 1040279 yhbY Escherichia coli CFT073 RNA-binding protein YhbY NP_755803.1 3761422 D 199310 CDS NP_755804.1 26249764 1040284 complement(3761871..3762347) 1 NC_004431.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3762347 greA 1040284 greA Escherichia coli CFT073 transcription elongation factor GreA NP_755804.1 3761871 R 199310 CDS NP_755805.1 26249765 1040285 3762596..3764029 1 NC_004431.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3764029 dacB 1040285 dacB Escherichia coli CFT073 D-alanyl-D-alanine carboxypeptidase/endopeptidase NP_755805.1 3762596 D 199310 CDS NP_755806.1 26249766 1040289 complement(3764070..3765242) 1 NC_004431.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3765242 obgE 1040289 obgE Escherichia coli CFT073 GTPase ObgE NP_755806.1 3764070 R 199310 CDS NP_755807.1 26249767 1040290 complement(3765258..3766223) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3184; Escherichia coli O157:H7 ortholog: z4546; transport protein YhbE 3766223 yhbE 1040290 yhbE Escherichia coli CFT073 transport protein YhbE NP_755807.1 3765258 R 199310 CDS NP_755808.1 26249768 1040292 complement(3766350..3766607) 1 NC_004431.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3766607 rpmA 1040292 rpmA Escherichia coli CFT073 50S ribosomal protein L27 NP_755808.1 3766350 R 199310 CDS NP_755809.1 26249769 1040293 3766437..3766562 1 NC_004431.1 hypothetical protein 3766562 1040293 c3943 Escherichia coli CFT073 hypothetical protein NP_755809.1 3766437 D 199310 CDS NP_755810.1 26249770 1040295 3766601..3767146 1 NC_004431.1 hypothetical protein 3767146 1040295 c3944 Escherichia coli CFT073 hypothetical protein NP_755810.1 3766601 D 199310 CDS NP_755811.1 26249771 1040301 3767198..3768169 1 NC_004431.1 Escherichia coli K-12 ortholog: b3187; Escherichia coli O157:H7 ortholog: z4550; octaprenyl diphosphate synthase 3768169 ispB 1040301 ispB Escherichia coli CFT073 octaprenyl diphosphate synthase NP_755811.1 3767198 D 199310 CDS NP_755812.1 26249772 1040303 3768402..3768680 1 NC_004431.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3768680 nlp 1040303 nlp Escherichia coli CFT073 DNA-binding transcriptional regulator Nlp NP_755812.1 3768402 D 199310 CDS NP_755813.1 26249773 1040304 complement(3768728..3769987) 1 NC_004431.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3769987 murA 1040304 murA Escherichia coli CFT073 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_755813.1 3768728 R 199310 CDS NP_755814.1 26249774 1040305 complement(3770042..3770311) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3190; Escherichia coli O157:H7 ortholog: z4553; hypothetical protein 3770311 yrbA 1040305 yrbA Escherichia coli CFT073 hypothetical protein NP_755814.1 3770042 R 199310 CDS NP_755815.1 26249775 1040307 3770108..3770449 1 NC_004431.1 hypothetical protein 3770449 1040307 c3949 Escherichia coli CFT073 hypothetical protein NP_755815.1 3770108 D 199310 CDS NP_755816.1 26249776 1040308 complement(3770456..3770845) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3191; Escherichia coli O157:H7 ortholog: z4554; hypothetical protein 3770845 yrbB 1040308 yrbB Escherichia coli CFT073 hypothetical protein NP_755816.1 3770456 R 199310 CDS NP_755817.1 26249777 1040309 3770737..3771372 1 NC_004431.1 hypothetical protein 3771372 1040309 c3951 Escherichia coli CFT073 hypothetical protein NP_755817.1 3770737 D 199310 CDS NP_755818.1 26249778 1040310 complement(3770749..3771384) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3192; Escherichia coli O157:H7 ortholog: z4555; hypothetical protein 3771384 yrbC 1040310 yrbC Escherichia coli CFT073 hypothetical protein NP_755818.1 3770749 R 199310 CDS NP_755819.1 26249779 1040311 complement(3771403..3771969) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3193; Escherichia coli O157:H7 ortholog: z4556; hypothetical protein 3771969 yrbD 1040311 yrbD Escherichia coli CFT073 hypothetical protein NP_755819.1 3771403 R 199310 CDS NP_755820.1 26249780 1040312 complement(3771959..3772741) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3194; Escherichia coli O157:H7 ortholog: z4557; hypothetical protein 3772741 yrbE 1040312 yrbE Escherichia coli CFT073 hypothetical protein NP_755820.1 3771959 R 199310 CDS NP_755821.1 26249781 1040316 complement(3772749..3773558) 1 NC_004431.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF 3773558 yrbF 1040316 yrbF Escherichia coli CFT073 ABC transporter ATP-binding protein YrbF NP_755821.1 3772749 R 199310 CDS NP_755822.1 26249782 1040317 3773768..3774745 1 NC_004431.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3774745 yrbG 1040317 yrbG Escherichia coli CFT073 calcium/sodium:proton antiporter NP_755822.1 3773768 D 199310 CDS NP_755823.1 26249783 1040318 3774738..3775745 1 NC_004431.1 Escherichia coli K-12 ortholog: b3197; Escherichia coli O157:H7 ortholog: z4560; D-arabinose 5-phosphate isomerase 3775745 1040318 c3957 Escherichia coli CFT073 D-arabinose 5-phosphate isomerase NP_755823.1 3774738 D 199310 CDS NP_755824.1 26249784 1040319 3775766..3776332 1 NC_004431.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3776332 yrbI 1040319 yrbI Escherichia coli CFT073 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase NP_755824.1 3775766 D 199310 CDS NP_755825.1 26249785 1040320 3776329..3776904 1 NC_004431.1 Escherichia coli K-12 ortholog: b3199; Escherichia coli O157:H7 ortholog: z4562; hypothetical protein 3776904 yrbK 1040320 yrbK Escherichia coli CFT073 hypothetical protein NP_755825.1 3776329 D 199310 CDS NP_755826.1 26249786 1040323 3776852..3777430 1 NC_004431.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3777430 yhbN 1040323 yhbN Escherichia coli CFT073 lipopolysaccharide transport periplasmic protein LptA NP_755826.1 3776852 D 199310 CDS NP_755827.1 26249787 1040324 3777437..3778162 1 NC_004431.1 Escherichia coli K-12 ortholog: b3201; Escherichia coli O157:H7 ortholog: z4564; ABC transporter ATP-binding protein YhbG 3778162 yhbG 1040324 yhbG Escherichia coli CFT073 ABC transporter ATP-binding protein YhbG NP_755827.1 3777437 D 199310 CDS NP_755828.1 26249788 1040326 3778210..3779643 1 NC_004431.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3779643 rpoN 1040326 rpoN Escherichia coli CFT073 RNA polymerase factor sigma-54 NP_755828.1 3778210 D 199310 CDS NP_755829.1 26249789 1040328 3779666..3779953 1 NC_004431.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3779953 yhbH 1040328 yhbH Escherichia coli CFT073 sigma(54) modulation protein NP_755829.1 3779666 D 199310 CDS NP_755830.1 26249790 1040329 3780047..3780562 1 NC_004431.1 Escherichia coli K-12 ortholog: b3204; Escherichia coli O157:H7 ortholog: z4567; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3780562 ptsN 1040329 ptsN Escherichia coli CFT073 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN NP_755830.1 3780047 D 199310 CDS NP_755831.1 26249791 1040332 3780608..3781462 1 NC_004431.1 Escherichia coli K-12 ortholog: b3205; Escherichia coli O157:H7 ortholog: z4568; hypothetical protein 3781462 yhbJ 1040332 yhbJ Escherichia coli CFT073 hypothetical protein NP_755831.1 3780608 D 199310 CDS NP_755832.1 26249792 1040333 3781459..3781731 1 NC_004431.1 Nitrogen related HPr; Escherichia coli K-12 ortholog: b3206; Escherichia coli O157:H7 ortholog: z4569; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3781731 ptsO 1040333 ptsO Escherichia coli CFT073 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) NP_755832.1 3781459 D 199310 CDS NP_755833.1 26249793 1040335 3781944..3782576 1 NC_004431.1 Escherichia coli K-12 ortholog: b3207; Escherichia coli O157:H7 ortholog: z4570; hypothetical protein 3782576 yrbL 1040335 yrbL Escherichia coli CFT073 hypothetical protein NP_755833.1 3781944 D 199310 CDS NP_755834.1 26249794 1040336 complement(3782573..3783301) 1 NC_004431.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3783301 mtgA 1040336 mtgA Escherichia coli CFT073 monofunctional biosynthetic peptidoglycan transglycosylase NP_755834.1 3782573 R 199310 CDS NP_755835.1 26249795 1040338 complement(3783298..3783951) 1 NC_004431.1 Sigma cross-reacting protein 27A; Escherichia coli K-12 ortholog: b3209; Escherichia coli O157:H7 ortholog: z4573; isoprenoid biosynthesis protein with amidotransferase-like domain 3783951 yhbL 1040338 yhbL Escherichia coli CFT073 isoprenoid biosynthesis protein with amidotransferase-like domain NP_755835.1 3783298 R 199310 CDS NP_755836.1 26249796 1040339 complement(3784181..3786517) 1 NC_004431.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3786517 arcB 1040339 arcB Escherichia coli CFT073 aerobic respiration control sensor protein ArcB NP_755836.1 3784181 R 199310 CDS NP_755837.1 26249797 1040340 complement(3786613..3787479) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3211; Escherichia coli O157:H7 ortholog: z4575; hypothetical protein 3787479 yhcC 1040340 yhcC Escherichia coli CFT073 hypothetical protein NP_755837.1 3786613 R 199310 CDS NP_755838.1 26249798 1040341 complement(3787807..3787944) 1 NC_004431.1 hypothetical protein 3787944 1040341 c3972 Escherichia coli CFT073 hypothetical protein NP_755838.1 3787807 R 199310 CDS NP_755839.2 161486106 1040342 3788124..3792677 1 NC_004431.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3792677 gltB 1040342 gltB Escherichia coli CFT073 glutamate synthase subunit alpha NP_755839.2 3788124 D 199310 CDS NP_755840.1 26249800 1040344 3792690..3794108 1 NC_004431.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3794108 gltD 1040344 gltD Escherichia coli CFT073 glutamate synthase subunit beta NP_755840.1 3792690 D 199310 CDS NP_755841.1 26249801 1040345 complement(3794176..3794640) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3221; Escherichia coli O157:H7 ortholog: z4579; hypothetical protein 3794640 yhcH 1040345 yhcH Escherichia coli CFT073 hypothetical protein NP_755841.1 3794176 R 199310 CDS NP_755842.2 161486105 1040347 complement(3794637..3795512) 1 NC_004431.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3795512 1040347 c3976 Escherichia coli CFT073 N-acetylmannosamine kinase NP_755842.2 3794637 R 199310 CDS NP_755843.1 26249803 1040348 complement(3795509..3796240) 1 NC_004431.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3796240 yhcJ 1040348 yhcJ Escherichia coli CFT073 N-acetylmannosamine-6-phosphate 2-epimerase NP_755843.1 3795509 R 199310 CDS NP_755844.2 161486104 1040349 complement(3796246..3797736) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3224; Escherichia coli O157:H7 ortholog: z4582; sialic acid transporter 3797736 nanT 1040349 nanT Escherichia coli CFT073 sialic acid transporter NP_755844.2 3796246 R 199310 CDS NP_755845.1 26249805 1040350 complement(3797845..3798738) 1 NC_004431.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3798738 nanA 1040350 nanA Escherichia coli CFT073 N-acetylneuraminate lyase NP_755845.1 3797845 R 199310 CDS NP_755846.1 26249806 1040351 complement(3798860..3799651) 1 NC_004431.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3799651 yhcK 1040351 yhcK Escherichia coli CFT073 transcriptional regulator NanR NP_755846.1 3798860 R 199310 CDS NP_755847.1 26249807 1040352 complement(3799759..3800256) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3228; Escherichia coli O157:H7 ortholog: z4586; ClpXP protease specificity-enhancing factor 3800256 sspB 1040352 sspB Escherichia coli CFT073 ClpXP protease specificity-enhancing factor NP_755847.1 3799759 R 199310 CDS NP_755848.1 26249808 1040353 complement(3800262..3800900) 1 NC_004431.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3800900 sspA 1040353 sspA Escherichia coli CFT073 stringent starvation protein A NP_755848.1 3800262 R 199310 CDS NP_755849.1 26249809 1040354 3800842..3801051 1 NC_004431.1 hypothetical protein 3801051 1040354 c3983 Escherichia coli CFT073 hypothetical protein NP_755849.1 3800842 D 199310 CDS NP_755850.1 26249810 1040355 complement(3801295..3801687) 1 NC_004431.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3801687 rpsI 1040355 rpsI Escherichia coli CFT073 30S ribosomal protein S9 NP_755850.1 3801295 R 199310 CDS NP_755851.2 161486103 1040357 complement(3801703..3802131) 1 NC_004431.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3802131 rplM 1040357 rplM Escherichia coli CFT073 50S ribosomal protein L13 NP_755851.2 3801703 R 199310 CDS NP_755852.1 26249812 1040358 complement(3802351..3803478) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3232; Escherichia coli O157:H7 ortholog: z4591; hypothetical protein 3803478 yhcM 1040358 yhcM Escherichia coli CFT073 hypothetical protein NP_755852.1 3802351 R 199310 CDS NP_755853.1 26249813 1040360 3803666..3804070 1 NC_004431.1 Escherichia coli K-12 ortholog: b3233; Escherichia coli O157:H7 ortholog: z4592; cytochrome d ubiquinol oxidase subunit III 3804070 yhcB 1040360 yhcB Escherichia coli CFT073 cytochrome d ubiquinol oxidase subunit III NP_755853.1 3803666 D 199310 CDS NP_755854.1 26249814 1040362 3803718..3804131 1 NC_004431.1 hypothetical protein 3804131 1040362 c3988 Escherichia coli CFT073 hypothetical protein NP_755854.1 3803718 D 199310 CDS NP_755855.1 26249815 1040363 3804182..3805591 1 NC_004431.1 Escherichia coli K-12 ortholog: b3234; Escherichia coli O157:H7 ortholog: z4593; serine endoprotease 3805591 degQ 1040363 degQ Escherichia coli CFT073 serine endoprotease NP_755855.1 3804182 D 199310 CDS NP_755856.1 26249816 1040366 3805681..3806748 1 NC_004431.1 Escherichia coli K-12 ortholog: b3235; Escherichia coli O157:H7 ortholog: z4594; serine endoprotease 3806748 degS 1040366 degS Escherichia coli CFT073 serine endoprotease NP_755856.1 3805681 D 199310 CDS NP_755857.2 161486102 1040367 complement(3806811..3807749) 1 NC_004431.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3807749 mdh 1040367 mdh Escherichia coli CFT073 malate dehydrogenase NP_755857.2 3806811 R 199310 CDS NP_755858.1 26249818 1040368 3808184..3808654 1 NC_004431.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3808654 argR 1040368 argR Escherichia coli CFT073 arginine repressor ArgR NP_755858.1 3808184 D 199310 CDS NP_755859.1 26249819 1040370 3808967..3809281 1 NC_004431.1 Escherichia coli K-12 ortholog: b3238; Escherichia coli O157:H7 ortholog: z4597; hypothetical protein 3809281 yhcN 1040370 yhcN Escherichia coli CFT073 hypothetical protein NP_755859.1 3808967 D 199310 CDS NP_755860.1 26249820 1040371 complement(3809336..3809608) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3239; Escherichia coli O157:H7 ortholog: z4598; hypothetical protein 3809608 yhcO 1040371 yhcO Escherichia coli CFT073 hypothetical protein NP_755860.1 3809336 R 199310 CDS NP_755861.1 26249821 1040372 complement(3809700..3811667) 1 NC_004431.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3811667 yhcP 1040372 yhcP Escherichia coli CFT073 p-hydroxybenzoic acid efflux subunit AaeB NP_755861.1 3809700 R 199310 CDS NP_755862.1 26249822 1040374 complement(3811673..3812605) 1 NC_004431.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3812605 yhcQ 1040374 yhcQ Escherichia coli CFT073 p-hydroxybenzoic acid efflux subunit AaeA NP_755862.1 3811673 R 199310 CDS NP_755863.2 161486101 1040375 complement(3812613..3812816) 1 NC_004431.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3812816 yhcR 1040375 yhcR Escherichia coli CFT073 hypothetical protein NP_755863.2 3812613 R 199310 CDS NP_755864.1 26249824 1040376 3812999..3813928 1 NC_004431.1 Escherichia coli K-12 ortholog: b3243; Escherichia coli O157:H7 ortholog: z4602; DNA-binding transcriptional regulator 3813928 yhcS 1040376 yhcS Escherichia coli CFT073 DNA-binding transcriptional regulator NP_755864.1 3812999 D 199310 CDS NP_755865.1 26249825 1040379 complement(3814056..3815501) 1 NC_004431.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3815501 tldD 1040379 tldD Escherichia coli CFT073 protease TldD NP_755865.1 3814056 R 199310 CDS NP_755866.1 26249826 1040382 complement(3815657..3819457) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604; hypothetical protein 3819457 yhdP 1040382 yhdP Escherichia coli CFT073 hypothetical protein NP_755866.1 3815657 R 199310 CDS NP_755867.2 161486100 1040383 complement(3819525..3820994) 1 NC_004431.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3820994 cafA 1040383 cafA Escherichia coli CFT073 ribonuclease G NP_755867.2 3819525 R 199310 CDS NP_755868.1 26249828 1040384 complement(3820984..3821577) 1 NC_004431.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3821577 maf 1040384 maf Escherichia coli CFT073 Maf-like protein NP_755868.1 3820984 R 199310 CDS NP_755869.1 26249829 1040385 complement(3821586..3822074) 1 NC_004431.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3822074 mreD 1040385 mreD Escherichia coli CFT073 rod shape-determining protein MreD NP_755869.1 3821586 R 199310 CDS YP_004853822.1 347357916 1040386 complement(3822058..3822189) 1 NC_004431.1 hypothetical protein 3822189 1040386 c4004 Escherichia coli CFT073 hypothetical protein YP_004853822.1 3822058 R 199310 CDS NP_755871.1 26249831 1040387 complement(3822074..3823177) 1 NC_004431.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3823177 mreC 1040387 mreC Escherichia coli CFT073 rod shape-determining protein MreC NP_755871.1 3822074 R 199310 CDS NP_755872.2 229106370 1040388 complement(3823243..3824286) 1 NC_004431.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3824286 mreB 1040388 mreB Escherichia coli CFT073 rod shape-determining protein MreB NP_755872.2 3823243 R 199310 CDS NP_755873.1 26249833 1040389 3824394..3824582 1 NC_004431.1 hypothetical protein 3824582 1040389 c4007 Escherichia coli CFT073 hypothetical protein NP_755873.1 3824394 D 199310 CDS NP_755874.1 26249834 1040390 complement(3824591..3826531) 1 NC_004431.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3826531 yhdA 1040390 yhdA Escherichia coli CFT073 regulatory protein CsrD NP_755874.1 3824591 R 199310 CDS NP_755875.1 26249835 1040391 3826683..3827657 1 NC_004431.1 Escherichia coli K-12 ortholog: b3253; Escherichia coli O157:H7 ortholog: z4612; hypothetical protein 3827657 yhdH 1040391 yhdH Escherichia coli CFT073 hypothetical protein NP_755875.1 3826683 D 199310 CDS NP_755876.1 26249836 1040392 3827694..3827858 1 NC_004431.1 hypothetical protein 3827858 1040392 c4010 Escherichia coli CFT073 hypothetical protein NP_755876.1 3827694 D 199310 CDS NP_755877.1 26249837 1040393 3828635..3829105 1 NC_004431.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3829105 accB 1040393 accB Escherichia coli CFT073 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NP_755877.1 3828635 D 199310 CDS NP_755878.2 161486099 1040394 3829116..3830465 1 NC_004431.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3830465 accC 1040394 accC Escherichia coli CFT073 acetyl-CoA carboxylase biotin carboxylase subunit NP_755878.2 3829116 D 199310 CDS NP_755879.1 26249839 1040395 complement(3830557..3831603) 1 NC_004431.1 Residues 10 to 332 of 348 are 34.70 pct identical to residues 18 to 355 of 355 from GenPept.129 : >emb|CAB55728.1| (AL117387) hypothetical protein SCF41.25 [Streptomyces coelicolor A3(2)]; hypothetical protein 3831603 1040395 c4013 Escherichia coli CFT073 hypothetical protein NP_755879.1 3830557 R 199310 CDS NP_755880.1 26249840 1040397 complement(3831600..3832562) 1 NC_004431.1 Residues 4 to 312 of 320 are 54.98 pct identical to residues 5 to 315 of 315 from GenPept.129 : >gb|AAL22123.1| (AE008850) sugar kinase, ribokinase family [Salmonella typhimurium LT2]; hypothetical protein 3832562 1040397 c4014 Escherichia coli CFT073 hypothetical protein NP_755880.1 3831600 R 199310 CDS NP_755881.1 26249841 1040398 complement(3832584..3833573) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3750; Escherichia coli O157:H7 ortholog: z5690; ribose ABC transporter permease 3833573 1040398 c4015 Escherichia coli CFT073 ribose ABC transporter permease NP_755881.1 3832584 R 199310 CDS NP_755882.1 26249842 1040399 complement(3833574..3835100) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3749; Escherichia coli O157:H7 ortholog: z5250; ribose ABC transporter ATP-binding protein 3835100 1040399 c4016 Escherichia coli CFT073 ribose ABC transporter ATP-binding protein NP_755882.1 3833574 R 199310 CDS NP_755883.1 26249843 1040401 complement(3835131..3836027) 1 NC_004431.1 Ribose-binding protein; Residues 5 to 298 of 298 are 60.67 pct identical to residues 2 to 296 of 296 from GenPept.129 : >emb|CAC49355.1| (AL603645) sugar uptake ABC transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti]; ribose ABC transporter 3836027 1040401 c4017 Escherichia coli CFT073 ribose ABC transporter NP_755883.1 3835131 R 199310 CDS NP_755884.1 26249844 1040402 complement(3836057..3836911) 1 NC_004431.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3836911 gatY 1040402 gatY Escherichia coli CFT073 tagatose-bisphosphate aldolase NP_755884.1 3836057 R 199310 CDS NP_755885.1 26249845 1040404 3836886..3837014 1 NC_004431.1 hypothetical protein 3837014 1040404 c4019 Escherichia coli CFT073 hypothetical protein NP_755885.1 3836886 D 199310 CDS NP_755886.1 26249846 1040407 3837253..3838083 1 NC_004431.1 Residues 8 to 270 of 276 are 42.00 pct identical to residues 3 to 270 of 277 from GenPept.129 : >gb|AAL22124.1| (AE008850) aga operon transcriptional repressor (DeoR family) [Salmonella typhimurium LT2]; hypothetical protein 3838083 1040407 c4020 Escherichia coli CFT073 hypothetical protein NP_755886.1 3837253 D 199310 CDS NP_755887.1 26249847 1040408 3838040..3839050 1 NC_004431.1 Residues 22 to 335 of 336 are 56.68 pct identical to residues 4 to 313 of 315 from GenPept.129 : >gb|AAL22123.1| (AE008850) sugar kinase, ribokinase family [Salmonella typhimurium LT2]; hypothetical protein 3839050 1040408 c4021 Escherichia coli CFT073 hypothetical protein NP_755887.1 3838040 D 199310 CDS NP_755888.1 26249848 1040412 3839125..3839385 1 NC_004431.1 Escherichia coli K-12 ortholog: b3257; Escherichia coli O157:H7 ortholog: z4617; hypothetical protein 3839385 yhdT 1040412 yhdT Escherichia coli CFT073 hypothetical protein NP_755888.1 3839125 D 199310 CDS NP_755889.2 161486098 1040421 3839375..3840826 1 NC_004431.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3840826 panF 1040421 panF Escherichia coli CFT073 sodium/panthothenate symporter NP_755889.2 3839375 D 199310 CDS NP_755890.1 26249850 1040428 3840838..3841719 1 NC_004431.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3841719 prmA 1040428 prmA Escherichia coli CFT073 ribosomal protein L11 methyltransferase NP_755890.1 3840838 D 199310 CDS NP_755891.1 26249851 1040429 complement(3841700..3841828) 1 NC_004431.1 hypothetical protein 3841828 1040429 c4025 Escherichia coli CFT073 hypothetical protein NP_755891.1 3841700 R 199310 CDS NP_755892.1 26249852 1040433 3842048..3843013 1 NC_004431.1 Escherichia coli K-12 ortholog: b3260; Escherichia coli O157:H7 ortholog: z4620; tRNA-dihydrouridine synthase B 3843013 yhdG 1040433 yhdG Escherichia coli CFT073 tRNA-dihydrouridine synthase B NP_755892.1 3842048 D 199310 CDS NP_755893.1 26249853 1040434 3843039..3843335 1 NC_004431.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3843335 fis 1040434 fis Escherichia coli CFT073 DNA-binding protein Fis NP_755893.1 3843039 D 199310 CDS NP_755894.2 161486097 1040437 3843421..3844305 1 NC_004431.1 Escherichia coli K-12 ortholog: b3262; Escherichia coli O157:H7 ortholog: z4622; methyltransferase 3844305 yhdJ 1040437 yhdJ Escherichia coli CFT073 methyltransferase NP_755894.2 3843421 D 199310 CDS NP_755895.1 26249855 1040438 3844362..3844568 1 NC_004431.1 Escherichia coli K-12 ortholog: b3263; Escherichia coli O157:H7 ortholog: z4623; hypothetical protein 3844568 yhdU 1040438 yhdU Escherichia coli CFT073 hypothetical protein NP_755895.1 3844362 D 199310 CDS NP_755896.1 26249856 1040440 complement(3844571..3845233) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3264; Escherichia coli O157:H7 ortholog: z4624; DNA-binding transcriptional regulator EnvR 3845233 envR 1040440 envR Escherichia coli CFT073 DNA-binding transcriptional regulator EnvR NP_755896.1 3844571 R 199310 CDS NP_755897.1 26249857 1040443 3845632..3846789 1 NC_004431.1 Protein envC; Escherichia coli K-12 ortholog: b3265; Escherichia coli O157:H7 ortholog: z4625; acriflavin resistance protein E 3846789 acrE 1040443 acrE Escherichia coli CFT073 acriflavin resistance protein E NP_755897.1 3845632 D 199310 CDS NP_755898.1 26249858 1040446 3846801..3849905 1 NC_004431.1 Protein envD; Escherichia coli K-12 ortholog: b3266; Escherichia coli O157:H7 ortholog: z0576; acriflavin resistance protein F 3849905 acrF 1040446 acrF Escherichia coli CFT073 acriflavin resistance protein F NP_755898.1 3846801 D 199310 CDS NP_755899.1 26249859 1040448 3850158..3850379 1 NC_004431.1 Escherichia coli K-12 ortholog: b3267; Escherichia coli O157:H7 ortholog: z4628; hypothetical protein 3850379 yhdV 1040448 yhdV Escherichia coli CFT073 hypothetical protein NP_755899.1 3850158 D 199310 CDS NP_755900.1 26249860 1040449 3850810..3851835 1 NC_004431.1 Escherichia coli K-12 ortholog: b3268; Escherichia coli O157:H7 ortholog: z4629; amino-acid ABC transporter binding protein yhdW 3851835 yhdW 1040449 yhdW Escherichia coli CFT073 amino-acid ABC transporter binding protein yhdW NP_755900.1 3850810 D 199310 CDS NP_755901.1 26249861 1040451 3851885..3853084 1 NC_004431.1 Escherichia coli K-12 ortholog: b3269; Escherichia coli O157:H7 ortholog: z4630; amino-acid ABC transporter permease YhdX 3853084 yhdX 1040451 yhdX Escherichia coli CFT073 amino-acid ABC transporter permease YhdX NP_755901.1 3851885 D 199310 CDS NP_755902.1 26249862 1040453 3853091..3854197 1 NC_004431.1 Escherichia coli K-12 ortholog: b3270; Escherichia coli O157:H7 ortholog: z4631; amino-acid ABC transporter permease YhdY 3854197 yhdY 1040453 yhdY Escherichia coli CFT073 amino-acid ABC transporter permease YhdY NP_755902.1 3853091 D 199310 CDS NP_755903.1 26249863 1040458 3854205..3854963 1 NC_004431.1 Escherichia coli K-12 ortholog: b3271; Escherichia coli O157:H7 ortholog: z4632; amino-acid ABC transporter ATP-binding protein YhdZ 3854963 yhdZ 1040458 yhdZ Escherichia coli CFT073 amino-acid ABC transporter ATP-binding protein YhdZ NP_755903.1 3854205 D 199310 CDS NP_755904.1 26249864 1040481 3860309..3861157 1 NC_004431.1 Escherichia coli K-12 ortholog: b3279; Escherichia coli O157:H7 ortholog: z4650; hypothetical protein 3861157 yrdA 1040481 yrdA Escherichia coli CFT073 hypothetical protein NP_755904.1 3860309 D 199310 CDS NP_755905.1 26249865 1040482 complement(3861133..3861390) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3280; Escherichia coli O157:H7 ortholog: z4651; hypothetical protein 3861390 yrdB 1040482 yrdB Escherichia coli CFT073 hypothetical protein NP_755905.1 3861133 R 199310 CDS NP_755906.1 26249866 1040483 complement(3861387..3862205) 1 NC_004431.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3862205 aroE 1040483 aroE Escherichia coli CFT073 shikimate 5-dehydrogenase NP_755906.1 3861387 R 199310 CDS NP_755907.1 26249867 1040484 complement(3862210..3862827) 1 NC_004431.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3862827 yrdC 1040484 yrdC Escherichia coli CFT073 ribosome maturation factor NP_755907.1 3862210 R 199310 CDS NP_755908.1 26249868 1040485 complement(3862787..3863329) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3283; Escherichia coli O157:H7 ortholog: z4654; hypothetical protein 3863329 yrdD 1040485 yrdD Escherichia coli CFT073 hypothetical protein NP_755908.1 3862787 R 199310 CDS NP_755909.1 26249869 1040486 complement(3863358..3863831) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3284; Escherichia coli O157:H7 ortholog: z4655; hypothetical protein 3863831 smg 1040486 smg Escherichia coli CFT073 hypothetical protein NP_755909.1 3863358 R 199310 CDS NP_755910.1 26249870 1040488 complement(3863803..3864927) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3286; Escherichia coli O157:H7 ortholog: z4656; DNA protecting protein DprA 3864927 smf 1040488 smf Escherichia coli CFT073 DNA protecting protein DprA NP_755910.1 3863803 R 199310 CDS NP_755911.1 26249871 1040490 3865057..3865566 1 NC_004431.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3865566 def 1040490 def Escherichia coli CFT073 peptide deformylase NP_755911.1 3865057 D 199310 CDS NP_755912.1 26249872 1040491 3865581..3866528 1 NC_004431.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3866528 fmt 1040491 fmt Escherichia coli CFT073 methionyl-tRNA formyltransferase NP_755912.1 3865581 D 199310 CDS NP_755913.1 26249873 1040492 3866580..3867869 1 NC_004431.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3867869 sun 1040492 sun Escherichia coli CFT073 16S rRNA methyltransferase GidB NP_755913.1 3866580 D 199310 CDS NP_755914.1 26249874 1040493 3867891..3869267 1 NC_004431.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3869267 trkA 1040493 trkA Escherichia coli CFT073 potassium transporter peripheral membrane component NP_755914.1 3867891 D 199310 CDS NP_755915.1 26249875 1040496 3869397..3869810 1 NC_004431.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3869810 mscL 1040496 mscL Escherichia coli CFT073 large-conductance mechanosensitive channel NP_755915.1 3869397 D 199310 CDS NP_755916.1 26249876 1040500 complement(3869807..3870025) 1 NC_004431.1 Residues 1 to 72 of 72 are 98.61 pct identical to residues 1 to 72 of 72 from SwissProt.40 : >sp|P36675|YHDL_ECOLI Hypothetical protein yhdL; regulator 3870025 yhdL 1040500 yhdL Escherichia coli CFT073 regulator NP_755916.1 3869807 R 199310 CDS NP_755917.1 26249877 1040501 complement(3870081..3870506) 1 NC_004431.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3870506 zntR 1040501 zntR Escherichia coli CFT073 zinc-responsive transcriptional regulator NP_755917.1 3870081 R 199310 CDS NP_755918.1 26249878 1040502 complement(3870517..3870885) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3293; Escherichia coli O157:H7 ortholog: z4663; hypothetical protein 3870885 yhdN 1040502 yhdN Escherichia coli CFT073 hypothetical protein NP_755918.1 3870517 R 199310 CDS NP_755919.1 26249879 1040503 complement(3870992..3871375) 1 NC_004431.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3871375 rplQ 1040503 rplQ Escherichia coli CFT073 50S ribosomal protein L17 NP_755919.1 3870992 R 199310 CDS NP_755920.1 26249880 1040504 complement(3871416..3872405) 1 NC_004431.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3872405 rpoA 1040504 rpoA Escherichia coli CFT073 DNA-directed RNA polymerase subunit alpha NP_755920.1 3871416 R 199310 CDS NP_755921.1 26249881 1040505 complement(3872431..3873051) 1 NC_004431.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3873051 rpsD 1040505 rpsD Escherichia coli CFT073 30S ribosomal protein S4 NP_755921.1 3872431 R 199310 CDS NP_755922.1 26249882 1040506 complement(3873085..3873474) 1 NC_004431.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3873474 rpsK 1040506 rpsK Escherichia coli CFT073 30S ribosomal protein S11 NP_755922.1 3873085 R 199310 CDS YP_004853823.1 347357939 1040511 3873121..3873501 1 NC_004431.1 hypothetical protein 3873501 1040511 c4059 Escherichia coli CFT073 hypothetical protein YP_004853823.1 3873121 D 199310 CDS NP_755924.1 26249884 1034925 complement(3873491..3873847) 1 NC_004431.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3873847 rpsM 1034925 rpsM Escherichia coli CFT073 30S ribosomal protein S13 NP_755924.1 3873491 R 199310 CDS NP_755925.1 26249885 1035715 complement(3874142..3875473) 1 NC_004431.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3875473 secY 1035715 secY Escherichia coli CFT073 preprotein translocase subunit SecY NP_755925.1 3874142 R 199310 CDS NP_755926.1 26249886 1035704 complement(3875481..3875915) 1 NC_004431.1 late assembly protein; 50S ribosomal protein L15 3875915 rplO 1035704 rplO Escherichia coli CFT073 50S ribosomal protein L15 NP_755926.1 3875481 R 199310 CDS NP_755927.1 26249887 1035652 complement(3875919..3876098) 1 NC_004431.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3876098 rpmD 1035652 rpmD Escherichia coli CFT073 50S ribosomal protein L30 NP_755927.1 3875919 R 199310 CDS NP_755928.1 26249888 1035734 3876072..3876623 1 NC_004431.1 hypothetical protein 3876623 1035734 c4064 Escherichia coli CFT073 hypothetical protein NP_755928.1 3876072 D 199310 CDS NP_755929.1 26249889 1035718 complement(3876102..3876605) 1 NC_004431.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3876605 rpsE 1035718 rpsE Escherichia coli CFT073 30S ribosomal protein S5 NP_755929.1 3876102 R 199310 CDS NP_755930.1 26249890 1035677 complement(3876620..3876973) 1 NC_004431.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3876973 rplR 1035677 rplR Escherichia coli CFT073 50S ribosomal protein L18 NP_755930.1 3876620 R 199310 CDS NP_755931.1 26249891 1035810 3876674..3877297 1 NC_004431.1 hypothetical protein 3877297 1035810 c4067 Escherichia coli CFT073 hypothetical protein NP_755931.1 3876674 D 199310 CDS NP_755932.1 26249892 1035767 complement(3876983..3877516) 1 NC_004431.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3877516 rplF 1035767 rplF Escherichia coli CFT073 50S ribosomal protein L6 NP_755932.1 3876983 R 199310 CDS NP_755933.1 26249893 1035726 3877382..3877939 1 NC_004431.1 hypothetical protein 3877939 1035726 c4069 Escherichia coli CFT073 hypothetical protein NP_755933.1 3877382 D 199310 CDS NP_755934.1 26249894 1035709 complement(3877529..3877921) 1 NC_004431.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3877921 rpsH 1035709 rpsH Escherichia coli CFT073 30S ribosomal protein S8 NP_755934.1 3877529 R 199310 CDS NP_755935.1 26249895 1035842 complement(3877955..3878260) 1 NC_004431.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3878260 rpsN 1035842 rpsN Escherichia coli CFT073 30S ribosomal protein S14 NP_755935.1 3877955 R 199310 CDS NP_755936.1 26249896 1035728 complement(3878275..3878814) 1 NC_004431.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3878814 rplE 1035728 rplE Escherichia coli CFT073 50S ribosomal protein L5 NP_755936.1 3878275 R 199310 CDS NP_755937.1 26249897 1035787 complement(3878829..3879143) 1 NC_004431.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3879143 rplX 1035787 rplX Escherichia coli CFT073 50S ribosomal protein L24 NP_755937.1 3878829 R 199310 CDS NP_755938.1 26249898 1035711 3879025..3879579 1 NC_004431.1 hypothetical protein 3879579 1035711 c4074 Escherichia coli CFT073 hypothetical protein NP_755938.1 3879025 D 199310 CDS NP_755939.1 26249899 1035870 complement(3879154..3879525) 1 NC_004431.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3879525 rplN 1035870 rplN Escherichia coli CFT073 50S ribosomal protein L14 NP_755939.1 3879154 R 199310 CDS NP_755940.1 26249900 1035830 complement(3879690..3879944) 1 NC_004431.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3879944 rpsQ 1035830 rpsQ Escherichia coli CFT073 30S ribosomal protein S17 NP_755940.1 3879690 R 199310 CDS NP_755941.1 26249901 1037580 complement(3879944..3880135) 1 NC_004431.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3880135 rpmC 1037580 rpmC Escherichia coli CFT073 50S ribosomal protein L29 NP_755941.1 3879944 R 199310 CDS YP_004853824.1 347357940 1035789 3880126..3880542 1 NC_004431.1 hypothetical protein 3880542 1035789 c4078 Escherichia coli CFT073 hypothetical protein YP_004853824.1 3880126 D 199310 CDS NP_755943.1 26249903 1040508 complement(3880135..3880545) 1 NC_004431.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3880545 rplP 1040508 rplP Escherichia coli CFT073 50S ribosomal protein L16 NP_755943.1 3880135 R 199310 CDS NP_755944.1 26249904 1039824 complement(3880558..3881259) 1 NC_004431.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3881259 rpsC 1039824 rpsC Escherichia coli CFT073 30S ribosomal protein S3 NP_755944.1 3880558 R 199310 CDS YP_004853825.1 347357941 1035976 3881259..3881666 1 NC_004431.1 hypothetical protein 3881666 1035976 c4081 Escherichia coli CFT073 hypothetical protein YP_004853825.1 3881259 D 199310 CDS NP_755946.1 26249906 1036587 complement(3881277..3881609) 1 NC_004431.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3881609 rplV 1036587 rplV Escherichia coli CFT073 50S ribosomal protein L22 NP_755946.1 3881277 R 199310 CDS NP_755947.1 26249907 1035959 complement(3881624..3881902) 1 NC_004431.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3881902 rpsS 1035959 rpsS Escherichia coli CFT073 30S ribosomal protein S19 NP_755947.1 3881624 R 199310 CDS NP_755948.1 26249908 1039809 3881886..3882812 1 NC_004431.1 hypothetical protein 3882812 1039809 c4084 Escherichia coli CFT073 hypothetical protein NP_755948.1 3881886 D 199310 CDS NP_755949.1 26249909 1036324 complement(3881919..3882740) 1 NC_004431.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3882740 rplB 1036324 rplB Escherichia coli CFT073 50S ribosomal protein L2 NP_755949.1 3881919 R 199310 CDS NP_755950.1 26249910 1035940 3882740..3883321 1 NC_004431.1 hypothetical protein 3883321 1035940 c4086 Escherichia coli CFT073 hypothetical protein NP_755950.1 3882740 D 199310 CDS NP_755951.1 26249911 1036387 complement(3882758..3883060) 1 NC_004431.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3883060 rplW 1036387 rplW Escherichia coli CFT073 50S ribosomal protein L23 NP_755951.1 3882758 R 199310 CDS YP_004853826.1 347357942 1037945 3883021..3883656 1 NC_004431.1 hypothetical protein 3883656 1037945 c4088 Escherichia coli CFT073 hypothetical protein YP_004853826.1 3883021 D 199310 CDS NP_755953.1 26249913 1036029 complement(3883057..3883662) 1 NC_004431.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3883662 rplD 1036029 rplD Escherichia coli CFT073 50S ribosomal protein L4 NP_755953.1 3883057 R 199310 CDS NP_755954.1 26249914 1037454 3883592..3884293 1 NC_004431.1 hypothetical protein 3884293 1037454 c4090 Escherichia coli CFT073 hypothetical protein NP_755954.1 3883592 D 199310 CDS NP_755955.1 26249915 1036019 complement(3883673..3884302) 1 NC_004431.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3884302 rplC 1036019 rplC Escherichia coli CFT073 50S ribosomal protein L3 NP_755955.1 3883673 R 199310 CDS NP_755956.1 26249916 1039718 complement(3884335..3884646) 1 NC_004431.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3884646 rpsJ 1039718 rpsJ Escherichia coli CFT073 30S ribosomal protein S10 NP_755956.1 3884335 R 199310 CDS NP_755957.1 26249917 1037588 complement(3884884..3885306) 1 NC_004431.1 calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO 3885306 pinO 1037588 pinO Escherichia coli CFT073 chromosome replication protein PioO NP_755957.1 3884884 R 199310 CDS NP_755958.1 26249918 1036057 complement(3885308..3886777) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3323; general secretion pathway protein A 3886777 yheD 1036057 yheD Escherichia coli CFT073 general secretion pathway protein A NP_755958.1 3885308 R 199310 CDS NP_755959.1 26249919 1040036 3886957..3887772 1 NC_004431.1 Escherichia coli K-12 ortholog: b3324; general secretion pathway protein C 3887772 yheE 1040036 yheE Escherichia coli CFT073 general secretion pathway protein C NP_755959.1 3886957 D 199310 CDS NP_755960.1 26249920 1036074 3887744..3889708 1 NC_004431.1 Escherichia coli K-12 ortholog: b3325; general secretion pathway protein D 3889708 yheF 1036074 yheF Escherichia coli CFT073 general secretion pathway protein D NP_755960.1 3887744 D 199310 CDS NP_755961.1 26249921 1036594 3889718..3891199 1 NC_004431.1 Type II traffic warden ATPase; Escherichia coli K-12 ortholog: b3326; Escherichia coli O157:H7 ortholog: z0117; general secretion pathway protein E 3891199 yheG 1036594 yheG Escherichia coli CFT073 general secretion pathway protein E NP_755961.1 3889718 D 199310 CDS NP_755962.1 26249922 1037565 3891196..3892392 1 NC_004431.1 Protein transport protein hofF; Escherichia coli K-12 ortholog: b3327; general secretion pathway protein F 3892392 hofF 1037565 hofF Escherichia coli CFT073 general secretion pathway protein F NP_755962.1 3891196 D 199310 CDS NP_755963.1 26249923 1036091 3892402..3892839 1 NC_004431.1 Protein transport protein hofG; Escherichia coli K-12 ortholog: b3328; general secretion pathway protein G 3892839 hofG 1036091 hofG Escherichia coli CFT073 general secretion pathway protein G NP_755963.1 3892402 D 199310 CDS NP_755964.1 26249924 1040247 3892847..3893356 1 NC_004431.1 Protein transport protein hofH; Escherichia coli K-12 ortholog: b3329; general secretion pathway protein H 3893356 hofH 1040247 hofH Escherichia coli CFT073 general secretion pathway protein H NP_755964.1 3892847 D 199310 CDS NP_755965.1 26249925 1040286 3893314..3893730 1 NC_004431.1 Escherichia coli K-12 ortholog: b3330; Escherichia coli O157:H7 ortholog: z5741; general secretion pathway protein I 3893730 yheH 1040286 yheH Escherichia coli CFT073 general secretion pathway protein I NP_755965.1 3893314 D 199310 CDS NP_755966.1 26249926 1036100 3893723..3894310 1 NC_004431.1 Escherichia coli K-12 ortholog: b3331; general secretion pathway protein J 3894310 yheI 1036100 yheI Escherichia coli CFT073 general secretion pathway protein J NP_755966.1 3893723 D 199310 CDS NP_755967.1 26249927 1037578 3894303..3895208 1 NC_004431.1 Escherichia coli K-12 ortholog: b3332; general secretion pathway protein K 3895208 yheJ 1037578 yheJ Escherichia coli CFT073 general secretion pathway protein K NP_755967.1 3894303 D 199310 CDS NP_755968.1 26249928 1036132 3895298..3896464 1 NC_004431.1 Escherichia coli K-12 ortholog: b3333; Escherichia coli O157:H7 ortholog: z2633; general secretion pathway protein L 3896464 yheK 1036132 yheK Escherichia coli CFT073 general secretion pathway protein L NP_755968.1 3895298 D 199310 CDS NP_755969.1 26249929 1040299 3896437..3896922 1 NC_004431.1 Transport protein pshM; Escherichia coli K-12 ortholog: b3334; general secretion pathway protein M 3896922 pshM 1040299 pshM Escherichia coli CFT073 general secretion pathway protein M NP_755969.1 3896437 D 199310 CDS NP_755970.1 26249930 1036161 3896922..3897599 1 NC_004431.1 Escherichia coli K-12 ortholog: b3335; Escherichia coli O157:H7 ortholog: z4693; bifunctional; leader peptidase 3897599 hofD 1036161 hofD Escherichia coli CFT073 leader peptidase NP_755970.1 3896922 D 199310 CDS NP_755971.1 26249931 1036151 complement(3897628..3898104) 1 NC_004431.1 iron storage protein; bacterioferritin 3898104 bfr 1036151 bfr Escherichia coli CFT073 bacterioferritin NP_755971.1 3897628 R 199310 CDS NP_755972.1 26249932 1039588 complement(3898176..3898370) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3337; Escherichia coli O157:H7 ortholog: z4696; bacterioferritin-associated ferredoxin 3898370 yheA 1039588 yheA Escherichia coli CFT073 bacterioferritin-associated ferredoxin NP_755972.1 3898176 R 199310 CDS NP_755973.1 26249933 1036186 complement(3898539..3901241) 1 NC_004431.1 has endochitinase/lysozyme activity; normally extracellular but does not appear to be secreted by wild-type Escherichia coli under standard laboratory conditions by the type II secretion pathway ; expression is controlled by H-NS; secreted endochitinase 3901241 chiA 1036186 chiA Escherichia coli CFT073 secreted endochitinase NP_755973.1 3898539 R 199310 CDS NP_755974.1 26249934 1040064 complement(3901326..3901484) 1 NC_004431.1 hypothetical protein 3901484 1040064 c4110 Escherichia coli CFT073 hypothetical protein NP_755974.1 3901326 R 199310 CDS NP_755975.2 161486096 1036191 complement(3901533..3902717) 1 NC_004431.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3902717 tuf 1036191 tuf Escherichia coli CFT073 elongation factor Tu NP_755975.2 3901533 R 199310 CDS NP_755976.1 26249936 1040244 complement(3902788..3904902) 1 NC_004431.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3904902 fusA 1040244 fusA Escherichia coli CFT073 elongation factor G NP_755976.1 3902788 R 199310 CDS NP_755977.1 26249937 1036224 3904978..3905412 1 NC_004431.1 Residues 8 to 142 of 144 are 42.96 pct identical to residues 55 to 189 of 197 from GenPept.129 : >gb|AAF63989.1| (AF214675) unknown in vivo-induced protein 131-19 [Pseudomonas aeruginosa]; hypothetical protein 3905412 1036224 c4113 Escherichia coli CFT073 hypothetical protein NP_755977.1 3904978 D 199310 CDS NP_755978.1 26249938 1036212 complement(3904999..3905469) 1 NC_004431.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3905469 rpsG 1036212 rpsG Escherichia coli CFT073 30S ribosomal protein S7 NP_755978.1 3904999 R 199310 CDS YP_004853827.1 347357943 1040239 3905482..3905943 1 NC_004431.1 hypothetical protein 3905943 1040239 c4115 Escherichia coli CFT073 hypothetical protein YP_004853827.1 3905482 D 199310 CDS NP_755980.2 161486095 1036280 complement(3905566..3905940) 1 NC_004431.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3905940 rpsL 1036280 rpsL Escherichia coli CFT073 30S ribosomal protein S12 NP_755980.2 3905566 R 199310 CDS NP_755981.1 26249941 1040051 complement(3906066..3906353) 1 NC_004431.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3906353 yheL 1040051 yheL Escherichia coli CFT073 sulfur transfer complex subunit TusB NP_755981.1 3906066 R 199310 CDS NP_755982.1 26249942 1036287 complement(3906361..3906720) 1 NC_004431.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3906720 yheM 1036287 yheM Escherichia coli CFT073 sulfur relay protein TusC NP_755982.1 3906361 R 199310 CDS NP_755983.1 26249943 1036284 complement(3906720..3907106) 1 NC_004431.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3907106 yheN 1036284 yheN Escherichia coli CFT073 sulfur transfer complex subunit TusD NP_755983.1 3906720 R 199310 CDS NP_755984.1 26249944 1036314 complement(3907106..3907840) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3346; Escherichia coli O157:H7 ortholog: z4704; hypothetical protein 3907840 yheO 1036314 yheO Escherichia coli CFT073 hypothetical protein NP_755984.1 3907106 R 199310 CDS NP_755985.1 26249945 1036405 complement(3907995..3908807) 1 NC_004431.1 rotamase; FKBP-type peptidylprolyl isomerase 3908807 fkpA 1036405 fkpA Escherichia coli CFT073 FKBP-type peptidylprolyl isomerase NP_755985.1 3907995 R 199310 CDS NP_755986.1 26249946 1036578 3909028..3909246 1 NC_004431.1 Escherichia coli K-12 ortholog: b3348; Escherichia coli O157:H7 ortholog: z4706; hypothetical protein 3909246 slyX 1036578 slyX Escherichia coli CFT073 hypothetical protein NP_755986.1 3909028 D 199310 CDS NP_755987.1 26249947 1036353 complement(3909295..3909885) 1 NC_004431.1 rotamase; FKBP-type peptidylprolyl isomerase 3909885 slyD 1036353 slyD Escherichia coli CFT073 FKBP-type peptidylprolyl isomerase NP_755987.1 3909295 R 199310 CDS NP_755988.1 26249948 1036326 complement(3909980..3910180) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4708; hypothetical protein 3910180 1036326 c4124 Escherichia coli CFT073 hypothetical protein NP_755988.1 3909980 R 199310 CDS NP_755989.1 26249949 1036618 complement(3910190..3911995) 1 NC_004431.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3911995 kefB 1036618 kefB Escherichia coli CFT073 glutathione-regulated potassium-efflux system protein KefB NP_755989.1 3910190 R 199310 CDS NP_755990.1 26249950 1036379 complement(3911995..3912549) 1 NC_004431.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3912549 yheR 1036379 yheR Escherichia coli CFT073 glutathione-regulated potassium-efflux system ancillary protein KefG NP_755990.1 3911995 R 199310 CDS NP_755991.1 26249951 1036362 3912677..3914590 1 NC_004431.1 Escherichia coli K-12 ortholog: b3352; Escherichia coli O157:H7 ortholog: z4713; ABC transporter ATP-binding protein 3914590 yheS 1036362 yheS Escherichia coli CFT073 ABC transporter ATP-binding protein NP_755991.1 3912677 D 199310 CDS NP_755992.1 26249952 1035646 3914590..3915612 1 NC_004431.1 Escherichia coli K-12 ortholog: b3353; Escherichia coli O157:H7 ortholog: z4714; hydrolase 3915612 yheT 1035646 yheT Escherichia coli CFT073 hydrolase NP_755992.1 3914590 D 199310 CDS NP_755993.1 26249953 1036671 3915606..3915824 1 NC_004431.1 Escherichia coli K-12 ortholog: b3354; Escherichia coli O157:H7 ortholog: z4715; hypothetical protein 3915824 yheU 1036671 yheU Escherichia coli CFT073 hypothetical protein NP_755993.1 3915606 D 199310 CDS NP_755994.1 26249954 1036463 3915878..3916747 1 NC_004431.1 Escherichia coli K-12 ortholog: b3355; Escherichia coli O157:H7 ortholog: z4716; phosphoribulokinase 3916747 prkB 1036463 prkB Escherichia coli CFT073 phosphoribulokinase NP_755994.1 3915878 D 199310 CDS NP_755995.1 26249955 1036450 complement(3916802..3917206) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3356; Escherichia coli O157:H7 ortholog: z4717; hypothetical protein 3917206 yhfA 1036450 yhfA Escherichia coli CFT073 hypothetical protein NP_755995.1 3916802 R 199310 CDS NP_755996.1 26249956 1036667 3917508..3918140 1 NC_004431.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3918140 crp 1036667 crp Escherichia coli CFT073 cAMP-regulatory protein NP_755996.1 3917508 D 199310 CDS NP_755997.1 26249957 1035992 3918179..3920281 1 NC_004431.1 Escherichia coli K-12 ortholog: b3358; Escherichia coli O157:H7 ortholog: z4719; hypothetical protein 3920281 yhfK 1035992 yhfK Escherichia coli CFT073 hypothetical protein NP_755997.1 3918179 D 199310 CDS NP_755998.1 26249958 1038036 complement(3920348..3921568) 1 NC_004431.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 3921568 argD 1038036 argD Escherichia coli CFT073 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein NP_755998.1 3920348 R 199310 CDS NP_755999.1 26249959 1036658 complement(3921654..3922217) 1 NC_004431.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3922217 pabA 1036658 pabA Escherichia coli CFT073 para-aminobenzoate synthase component II NP_755999.1 3921654 R 199310 CDS NP_756000.1 26249960 1036690 complement(3922249..3922851) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3361; Escherichia coli O157:H7 ortholog: z4722; cell filamentation protein Fic 3922851 fic 1036690 fic Escherichia coli CFT073 cell filamentation protein Fic NP_756000.1 3922249 R 199310 CDS NP_756001.1 26249961 1036670 complement(3922841..3923008) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3362; Escherichia coli O157:H7 ortholog: z4723; hypothetical protein 3923008 yhfG 1036670 yhfG Escherichia coli CFT073 hypothetical protein NP_756001.1 3922841 R 199310 CDS NP_756002.1 26249962 1036663 complement(3923113..3923685) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3363; Escherichia coli O157:H7 ortholog: z4724; peptidyl-prolyl cis-trans isomerase A (rotamase A) 3923685 ppiA 1036663 ppiA Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase A (rotamase A) NP_756002.1 3923113 R 199310 CDS NP_756003.1 26249963 1036682 3923956..3925137 1 NC_004431.1 Escherichia coli K-12 ortholog: b3364; Escherichia coli O157:H7 ortholog: z4725; hypothetical protein 3925137 yhfC 1036682 yhfC Escherichia coli CFT073 hypothetical protein NP_756003.1 3923956 D 199310 CDS NP_756004.1 26249964 1038044 complement(3925270..3925446) 1 NC_004431.1 hypothetical protein 3925446 1038044 c4140 Escherichia coli CFT073 hypothetical protein NP_756004.1 3925270 R 199310 CDS NP_756005.1 26249965 1036672 3925399..3927942 1 NC_004431.1 Escherichia coli K-12 ortholog: b3365; Escherichia coli O157:H7 ortholog: z4726; nitrite reductase [NAD(P)H] large subunit 3927942 nirB 1036672 nirB Escherichia coli CFT073 nitrite reductase [NAD(P)H] large subunit NP_756005.1 3925399 D 199310 CDS NP_756006.1 26249966 1036687 3927939..3928265 1 NC_004431.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3928265 nirD 1036687 nirD Escherichia coli CFT073 nitrite reductase small subunit NP_756006.1 3927939 D 199310 CDS NP_756007.1 26249967 1036675 3928391..3929197 1 NC_004431.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3929197 nirC 1036675 nirC Escherichia coli CFT073 nitrite transporter NirC NP_756007.1 3928391 D 199310 CDS NP_756008.1 26249968 1036683 3929216..3930589 1 NC_004431.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3930589 cysG 1036683 cysG Escherichia coli CFT073 siroheme synthase NP_756008.1 3929216 D 199310 CDS NP_756009.1 26249969 1036676 3930841..3931008 1 NC_004431.1 Escherichia coli K-12 ortholog: b3369; Escherichia coli O157:H7 ortholog: z4730; hypothetical protein 3931008 yhfL 1036676 yhfL Escherichia coli CFT073 hypothetical protein NP_756009.1 3930841 D 199310 CDS NP_756010.1 26249970 1036708 complement(3931116..3932201) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3376; hypothetical protein 3932201 yhfS 1036708 yhfS Escherichia coli CFT073 hypothetical protein NP_756010.1 3931116 R 199310 CDS NP_756011.1 26249971 1036673 complement(3932213..3933517) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3377; hypothetical protein 3933517 yhfT 1036673 yhfT Escherichia coli CFT073 hypothetical protein NP_756011.1 3932213 R 199310 CDS NP_756012.1 26249972 1036684 complement(3933529..3933921) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3378; hypothetical protein 3933921 yhfU 1036684 yhfU Escherichia coli CFT073 hypothetical protein NP_756012.1 3933529 R 199310 CDS NP_756013.1 26249973 1036715 complement(3933893..3934771) 1 NC_004431.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3934771 yhfV 1036715 yhfV Escherichia coli CFT073 hydrolase NP_756013.1 3933893 R 199310 CDS NP_756014.1 26249974 1036701 complement(3934768..3935994) 1 NC_004431.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; mutase 3935994 yhfW 1036701 yhfW Escherichia coli CFT073 mutase NP_756014.1 3934768 R 199310 CDS NP_756015.1 26249975 1036711 complement(3935995..3937158) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3381; hypothetical protein 3937158 yhfX 1036711 yhfX Escherichia coli CFT073 hypothetical protein NP_756015.1 3935995 R 199310 CDS NP_756016.1 26249976 1036697 complement(3937242..3937646) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3382; hypothetical protein 3937646 yhfY 1036697 yhfY Escherichia coli CFT073 hypothetical protein NP_756016.1 3937242 R 199310 CDS NP_756017.1 26249977 1036692 complement(3937621..3938469) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3383; hypothetical protein 3938469 yhfZ 1036692 yhfZ Escherichia coli CFT073 hypothetical protein NP_756017.1 3937621 R 199310 CDS NP_756018.1 26249978 1036689 complement(3938687..3939691) 1 NC_004431.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3939691 trpS 1036689 trpS Escherichia coli CFT073 tryptophanyl-tRNA synthetase NP_756018.1 3938687 R 199310 CDS NP_756019.1 26249979 1036709 complement(3939684..3940442) 1 NC_004431.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3940442 gph 1036709 gph Escherichia coli CFT073 phosphoglycolate phosphatase NP_756019.1 3939684 R 199310 CDS NP_756020.1 26249980 1036696 complement(3940435..3941112) 1 NC_004431.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3941112 rpe 1036696 rpe Escherichia coli CFT073 ribulose-phosphate 3-epimerase NP_756020.1 3940435 R 199310 CDS NP_756021.1 26249981 1036686 complement(3941130..3941966) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3387; Escherichia coli O157:H7 ortholog: z4740; DNA adenine methylase 3941966 dam 1036686 dam Escherichia coli CFT073 DNA adenine methylase NP_756021.1 3941130 R 199310 CDS NP_756022.1 26249982 1036700 complement(3942073..3943359) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3388; Escherichia coli O157:H7 ortholog: z4741; hypothetical protein 3943359 damX 1036700 damX Escherichia coli CFT073 hypothetical protein NP_756022.1 3942073 R 199310 CDS NP_756023.1 26249983 1036716 complement(3943451..3944539) 1 NC_004431.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3944539 aroB 1036716 aroB Escherichia coli CFT073 3-dehydroquinate synthase NP_756023.1 3943451 R 199310 CDS NP_756024.2 161486094 1036725 complement(3944596..3945117) 1 NC_004431.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3945117 aroK 1036725 aroK Escherichia coli CFT073 shikimate kinase I NP_756024.2 3944596 R 199310 CDS NP_756025.1 26249985 1036707 complement(3945518..3946756) 1 NC_004431.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3946756 hofQ 1036707 hofQ Escherichia coli CFT073 outer membrane porin HofQ NP_756025.1 3945518 R 199310 CDS NP_756026.1 26249986 1036733 complement(3946668..3947111) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3392; Escherichia coli O157:H7 ortholog: z4746; hypothetical protein 3947111 yrfA 1036733 yrfA Escherichia coli CFT073 hypothetical protein NP_756026.1 3946668 R 199310 CDS NP_756027.1 26249987 1036729 complement(3947062..3947502) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3393; Escherichia coli O157:H7 ortholog: z4747; hypothetical protein 3947502 yrfB 1036729 yrfB Escherichia coli CFT073 hypothetical protein NP_756027.1 3947062 R 199310 CDS NP_756028.1 26249988 1036719 complement(3947486..3948025) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3394; Escherichia coli O157:H7 ortholog: z4748; hypothetical protein 3948025 yrfC 1036719 yrfC Escherichia coli CFT073 hypothetical protein NP_756028.1 3947486 R 199310 CDS NP_756029.1 26249989 1036712 complement(3948025..3948831) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3395; Escherichia coli O157:H7 ortholog: z4749; hypothetical protein 3948831 yrfD 1036712 yrfD Escherichia coli CFT073 hypothetical protein NP_756029.1 3948025 R 199310 CDS NP_756030.2 229106369 1036736 3948924..3951476 1 NC_004431.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3951476 mrcA 1036736 mrcA Escherichia coli CFT073 peptidoglycan synthetase NP_756030.2 3948924 D 199310 CDS NP_756031.1 26249991 1036737 complement(3951642..3952202) 1 NC_004431.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3952202 nudE 1036737 nudE Escherichia coli CFT073 ADP-ribose diphosphatase NudE NP_756031.1 3951642 R 199310 CDS NP_756032.1 26249992 1036742 3952403..3952525 1 NC_004431.1 hypothetical protein 3952525 1036742 c4168 Escherichia coli CFT073 hypothetical protein NP_756032.1 3952403 D 199310 CDS NP_756033.1 26249993 1036743 3952522..3954657 1 NC_004431.1 Escherichia coli K-12 ortholog: b3398; Escherichia coli O157:H7 ortholog: z4752; membrane protein igaA-like protein 3954657 yrfF 1036743 yrfF Escherichia coli CFT073 membrane protein igaA-like protein NP_756033.1 3952522 D 199310 CDS NP_756034.1 26249994 1036730 3954677..3955390 1 NC_004431.1 Escherichia coli K-12 ortholog: b3399; Escherichia coli O157:H7 ortholog: z4753; hypothetical protein 3955390 yrfG 1036730 yrfG Escherichia coli CFT073 hypothetical protein NP_756034.1 3954677 D 199310 CDS NP_756035.1 26249995 1036720 3955401..3955802 1 NC_004431.1 HSP15; Escherichia coli K-12 ortholog: b3400; Escherichia coli O157:H7 ortholog: z4754; ribosome-associated heat shock protein Hsp15 3955802 yrfH 1036720 yrfH Escherichia coli CFT073 ribosome-associated heat shock protein Hsp15 NP_756035.1 3955401 D 199310 CDS NP_756036.2 161486093 1036731 3955827..3956705 1 NC_004431.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3956705 hslO 1036731 hslO Escherichia coli CFT073 Hsp33-like chaperonin NP_756036.2 3955827 D 199310 CDS NP_756037.1 26249997 1036726 complement(3956843..3958567) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3402; Escherichia coli O157:H7 ortholog: z4756; hypothetical protein 3958567 yhgE 1036726 yhgE Escherichia coli CFT073 hypothetical protein NP_756037.1 3956843 R 199310 CDS NP_756038.1 26249998 1036789 complement(3958573..3958701) 1 NC_004431.1 hypothetical protein 3958701 1036789 c4174 Escherichia coli CFT073 hypothetical protein NP_756038.1 3958573 R 199310 CDS NP_756039.1 26249999 1036738 complement(3958643..3958774) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4757; hypothetical protein 3958774 1036738 c4175 Escherichia coli CFT073 hypothetical protein NP_756039.1 3958643 R 199310 CDS NP_756040.1 26250000 1036732 3958877..3960568 1 NC_004431.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3960568 pckA 1036732 pckA Escherichia coli CFT073 phosphoenolpyruvate carboxykinase NP_756040.1 3958877 D 199310 CDS NP_756041.1 26250001 1036788 3960691..3960870 1 NC_004431.1 hypothetical protein 3960870 1036788 c4177 Escherichia coli CFT073 hypothetical protein NP_756041.1 3960691 D 199310 CDS NP_756042.1 26250002 1036746 3960843..3960995 1 NC_004431.1 hypothetical protein 3960995 1036746 c4178 Escherichia coli CFT073 hypothetical protein NP_756042.1 3960843 D 199310 CDS NP_756043.1 26250003 1036739 3961054..3961350 1 NC_004431.1 Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980; hypothetical protein 3961350 1036739 c4179 Escherichia coli CFT073 hypothetical protein NP_756043.1 3961054 D 199310 CDS NP_756044.1 26250004 1036734 complement(3961381..3962733) 1 NC_004431.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3962733 envZ 1036734 envZ Escherichia coli CFT073 osmolarity sensor protein NP_756044.1 3961381 R 199310 CDS NP_756045.1 26250005 1036818 complement(3962730..3963449) 1 NC_004431.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3963449 ompR 1036818 ompR Escherichia coli CFT073 osmolarity response regulator NP_756045.1 3962730 R 199310 CDS NP_756046.1 26250006 1036821 complement(3963539..3963724) 1 NC_004431.1 hypothetical protein 3963724 1036821 c4182 Escherichia coli CFT073 hypothetical protein NP_756046.1 3963539 R 199310 CDS NP_756047.2 161486092 1036741 3963677..3964153 1 NC_004431.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3964153 greB 1036741 greB Escherichia coli CFT073 transcription elongation factor GreB NP_756047.2 3963677 D 199310 CDS NP_756048.1 26250008 1036794 3964250..3966571 1 NC_004431.1 Escherichia coli K-12 ortholog: b3407; Escherichia coli O157:H7 ortholog: z4762; hypothetical protein 3966571 yhgF 1036794 yhgF Escherichia coli CFT073 hypothetical protein NP_756048.1 3964250 D 199310 CDS NP_756049.1 26250009 1036745 3967027..3967254 1 NC_004431.1 Escherichia coli K-12 ortholog: b3408; Escherichia coli O157:H7 ortholog: z4763; ferrous iron transport protein A 3967254 feoA 1036745 feoA Escherichia coli CFT073 ferrous iron transport protein A NP_756049.1 3967027 D 199310 CDS NP_756050.2 161486091 1036786 3967271..3969592 1 NC_004431.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3969592 feoB 1036786 feoB Escherichia coli CFT073 ferrous iron transport protein B NP_756050.2 3967271 D 199310 CDS NP_756051.1 26250011 1036850 3969583..3969828 1 NC_004431.1 Escherichia coli K-12 ortholog: b3410; Escherichia coli O157:H7 ortholog: z4765; hypothetical protein 3969828 yhgG 1036850 yhgG Escherichia coli CFT073 hypothetical protein NP_756051.1 3969583 D 199310 CDS NP_756052.1 26250012 1036851 3970061..3970654 1 NC_004431.1 Escherichia coli K-12 ortholog: b3411; Escherichia coli O157:H7 ortholog: z4766; hypothetical protein 3970654 yhgA 1036851 yhgA Escherichia coli CFT073 hypothetical protein NP_756052.1 3970061 D 199310 CDS NP_756053.1 26250013 1036795 complement(3970683..3971453) 1 NC_004431.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3971453 bioH 1036795 bioH Escherichia coli CFT073 carboxylesterase BioH NP_756053.1 3970683 R 199310 CDS NP_756054.2 161486090 1036787 3971491..3972174 1 NC_004431.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3972174 yhgH 1036787 yhgH Escherichia coli CFT073 gluconate periplasmic binding protein NP_756054.2 3971491 D 199310 CDS NP_756055.1 26250015 1036834 3972233..3972808 1 NC_004431.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3972808 yhgI 1036834 yhgI Escherichia coli CFT073 DNA uptake protein NP_756055.1 3972233 D 199310 CDS NP_756056.1 26250016 1036804 3973172..3974488 1 NC_004431.1 Gluconate permease; Escherichia coli K-12 ortholog: b3415; Escherichia coli O157:H7 ortholog: z4770; high-affinity gluconate transporter 3974488 gntT 1036804 gntT Escherichia coli CFT073 high-affinity gluconate transporter NP_756056.1 3973172 D 199310 CDS NP_756057.1 26250017 1036762 complement(3974599..3976683) 1 NC_004431.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3976683 malQ 1036762 malQ Escherichia coli CFT073 4-alpha-glucanotransferase NP_756057.1 3974599 R 199310 CDS NP_756058.1 26250018 1036869 complement(3976693..3979086) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3417; Escherichia coli O157:H7 ortholog: z4772; maltodextrin phosphorylase 3979086 malP 1036869 malP Escherichia coli CFT073 maltodextrin phosphorylase NP_756058.1 3976693 R 199310 CDS NP_756059.1 26250019 1036872 complement(3979431..3979577) 1 NC_004431.1 hypothetical protein 3979577 1036872 c4195 Escherichia coli CFT073 hypothetical protein NP_756059.1 3979431 R 199310 CDS NP_756060.1 26250020 1036838 3979709..3982414 1 NC_004431.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3982414 malT 1036838 malT Escherichia coli CFT073 transcriptional regulator MalT NP_756060.1 3979709 D 199310 CDS NP_756061.1 26250021 1036815 complement(3982457..3983476) 1 NC_004431.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3983476 1036815 c4197 Escherichia coli CFT073 RNA 3'-terminal-phosphate cyclase NP_756061.1 3982457 R 199310 CDS NP_756062.1 26250022 1036860 complement(3983477..3984766) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3421; Escherichia coli O157:H7 ortholog: z4779; protein rtcB 3984766 rtcB 1036860 rtcB Escherichia coli CFT073 protein rtcB NP_756062.1 3983477 R 199310 CDS NP_756063.1 26250023 1036845 3984892..3986490 1 NC_004431.1 Escherichia coli K-12 ortholog: b3422; Escherichia coli O157:H7 ortholog: z4780; transcriptional regulatory protein rtcR 3986490 rtcR 1036845 rtcR Escherichia coli CFT073 transcriptional regulatory protein rtcR NP_756063.1 3984892 D 199310 CDS NP_756064.1 26250024 1036800 complement(3986472..3987281) 1 NC_004431.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3987281 glpR 1036800 glpR Escherichia coli CFT073 DNA-binding transcriptional repressor GlpR NP_756064.1 3986472 R 199310 CDS NP_756065.1 26250025 1036898 complement(3987247..3988077) 1 NC_004431.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3988077 glpG 1036898 glpG Escherichia coli CFT073 intramembrane serine protease GlpG NP_756065.1 3987247 R 199310 CDS NP_756066.2 161486089 1036899 complement(3988122..3988448) 1 NC_004431.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3988448 glpE 1036899 glpE Escherichia coli CFT073 thiosulfate sulfurtransferase NP_756066.2 3988122 R 199310 CDS NP_756067.2 161486088 1036866 3988638..3990143 1 NC_004431.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3990143 glpD 1036866 glpD Escherichia coli CFT073 glycerol-3-phosphate dehydrogenase NP_756067.2 3988638 D 199310 CDS NP_756068.1 26250028 1036846 complement(3990197..3990802) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4787; hypothetical protein 3990802 1036846 c4204 Escherichia coli CFT073 hypothetical protein NP_756068.1 3990197 R 199310 CDS NP_756069.1 26250029 1036895 complement(3990805..3991572) 1 NC_004431.1 hypothetical protein 3991572 1036895 c4205 Escherichia coli CFT073 hypothetical protein NP_756069.1 3990805 R 199310 CDS NP_756070.1 26250030 1036867 complement(3991575..3992285) 1 NC_004431.1 hypothetical protein 3992285 1036867 c4206 Escherichia coli CFT073 hypothetical protein NP_756070.1 3991575 R 199310 CDS NP_756071.1 26250031 1036843 complement(3992579..3993589) 1 NC_004431.1 Residues 41 to 313 of 336 are 27.40 pct identical to residues 28 to 290 of 351 from GenPept.129 : >gb|AAG58691.1|AE005581_3 (AE005581) fimbrial protein [Escherichia coli O157:H7 EDL933]; fimbrial adhesin 3993589 1036843 c4207 Escherichia coli CFT073 fimbrial adhesin NP_756071.1 3992579 R 199310 CDS NP_756072.1 26250032 1036882 complement(3993608..3994405) 1 NC_004431.1 Residues 27 to 251 of 265 are 37.61 pct identical to residues 15 to 230 of 234 from GenPept.129 : >emb|CAD01181.1| (AL627265) fimbrial chaperone [Salmonella enterica subsp. enterica serovar Typhi]; fimbrial chaperone 3994405 1036882 c4208 Escherichia coli CFT073 fimbrial chaperone NP_756072.1 3993608 R 199310 CDS NP_756073.1 26250033 1036926 complement(3994350..3994907) 1 NC_004431.1 Residues 5 to 185 of 185 are 32.24 pct identical to residues 7 to 187 of 187 from GenPept.129 : >gb|AAG55429.1|AE005284_7 (AE005284) fimbrial-like protein [Escherichia coli O157:H7 EDL933]; minor fimbrial subunit 3994907 1036926 c4209 Escherichia coli CFT073 minor fimbrial subunit NP_756073.1 3994350 R 199310 CDS NP_756074.1 26250034 1036887 complement(3994873..3995325) 1 NC_004431.1 Residues 1 to 150 of 150 are 32.69 pct identical to residues 36 to 181 of 181 from GenPept.129 : >gb|AAL18989.1| (AE008694) fimbrial subunit [Salmonella typhimurium LT2]; minor fimbrial subunit 3995325 1036887 c4210 Escherichia coli CFT073 minor fimbrial subunit NP_756074.1 3994873 R 199310 CDS NP_756075.1 26250035 1036863 3995303..3995464 1 NC_004431.1 hypothetical protein 3995464 1036863 c4211 Escherichia coli CFT073 hypothetical protein NP_756075.1 3995303 D 199310 CDS NP_756076.1 26250036 1036923 complement(3995436..3998030) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0940; Escherichia coli O157:H7 ortholog: z5915; outer membrane usher protein ycbS 3998030 ycbS 1036923 ycbS Escherichia coli CFT073 outer membrane usher protein ycbS NP_756076.1 3995436 R 199310 CDS NP_756077.1 26250037 1036893 complement(3998067..3998846) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z2201; chaperone protein fimC 3998846 1036893 c4213 Escherichia coli CFT073 chaperone protein fimC NP_756077.1 3998067 R 199310 CDS NP_756078.1 26250038 1036874 complement(3998920..3999624) 1 NC_004431.1 Residues 56 to 234 of 234 are 32.96 pct identical to residues 26 to 178 of 178 from GenPept.129 : >gb|AAL22500.1| (AE008868) long polar fimbria [Salmonella typhimurium LT2]; major fimbrial subunit 3999624 1036874 c4214 Escherichia coli CFT073 major fimbrial subunit NP_756078.1 3998920 R 199310 CDS NP_756079.1 26250039 1036949 complement(4000119..4002566) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3428; Escherichia coli O157:H7 ortholog: z4790; glycogen phosphorylase 4002566 glgP 1036949 glgP Escherichia coli CFT073 glycogen phosphorylase NP_756079.1 4000119 R 199310 CDS NP_756080.1 26250040 1036951 complement(4002585..4004018) 1 NC_004431.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4004018 glgA 1036951 glgA Escherichia coli CFT073 glycogen synthase NP_756080.1 4002585 R 199310 CDS NP_756081.2 161486087 1036924 complement(4004018..4005313) 1 NC_004431.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4005313 glgC 1036924 glgC Escherichia coli CFT073 glucose-1-phosphate adenylyltransferase NP_756081.2 4004018 R 199310 CDS NP_756082.1 26250042 1036916 complement(4005331..4007304) 1 NC_004431.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme 4007304 glgX 1036916 glgX Escherichia coli CFT073 glycogen debranching enzyme NP_756082.1 4005331 R 199310 CDS NP_756083.1 26250043 1036905 complement(4007301..4009487) 1 NC_004431.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 4009487 glgB 1036905 glgB Escherichia coli CFT073 glycogen branching enzyme NP_756083.1 4007301 R 199310 CDS NP_756084.2 161486086 1036947 complement(4009760..4010863) 1 NC_004431.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4010863 asd 1036947 asd Escherichia coli CFT073 aspartate-semialdehyde dehydrogenase NP_756084.2 4009760 R 199310 CDS NP_756085.1 26250045 1036901 4011055..4011648 1 NC_004431.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4011648 yhgN 1036901 yhgN Escherichia coli CFT073 dITP- and XTP- hydrolase NP_756085.1 4011055 D 199310 CDS NP_756086.1 26250046 1036927 complement(4011694..4012989) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4799; DNA processing protein 4012989 1036927 c4222 Escherichia coli CFT073 DNA processing protein NP_756086.1 4011694 R 199310 CDS NP_756087.1 26250047 1036979 complement(4012896..4014995) 1 NC_004431.1 Residues 6 to 340 of 699 are 37.53 pct identical to residues 14 to 331 of 610 from MG1655 : b3822; hypothetical protein 4014995 1036979 c4223 Escherichia coli CFT073 hypothetical protein NP_756087.1 4012896 R 199310 CDS NP_756088.1 26250048 1036952 complement(4015133..4016473) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3436; Escherichia coli O157:H7 ortholog: z4804; low affinity gluconate transporter 4016473 gntU 1036952 gntU Escherichia coli CFT073 low affinity gluconate transporter NP_756088.1 4015133 R 199310 CDS NP_756089.2 161486085 1036939 complement(4016477..4017004) 1 NC_004431.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 4017004 gntK 1036939 gntK Escherichia coli CFT073 gluconate kinase 1 NP_756089.2 4016477 R 199310 CDS NP_756090.1 26250050 1036937 4016531..4017163 1 NC_004431.1 hypothetical protein 4017163 1036937 c4226 Escherichia coli CFT073 hypothetical protein NP_756090.1 4016531 D 199310 CDS NP_756091.1 26250051 1036975 complement(4017143..4018138) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3438; Escherichia coli O157:H7 ortholog: z4806; gluconate utilization system GNT-I transcriptional repressor 4018138 gntR 1036975 gntR Escherichia coli CFT073 gluconate utilization system GNT-I transcriptional repressor NP_756091.1 4017143 R 199310 CDS NP_756092.1 26250052 1036964 complement(4018231..4018926) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3439; Escherichia coli O157:H7 ortholog: z4807; hypothetical protein 4018926 yhhW 1036964 yhhW Escherichia coli CFT073 hypothetical protein NP_756092.1 4018231 R 199310 CDS NP_756093.1 26250053 1036945 complement(4019049..4020086) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3440; Escherichia coli O157:H7 ortholog: z4808; dehydrogenase 4020086 yhhX 1036945 yhhX Escherichia coli CFT073 dehydrogenase NP_756093.1 4019049 R 199310 CDS NP_756094.1 26250054 1036928 4020033..4020191 1 NC_004431.1 hypothetical protein 4020191 1036928 c4230 Escherichia coli CFT073 hypothetical protein NP_756094.1 4020033 D 199310 CDS NP_756095.1 26250055 1036961 4021144..4022322 1 NC_004431.1 Escherichia coli K-12 ortholog: b3442; hypothetical protein 4022322 yhhZ 1036961 yhhZ Escherichia coli CFT073 hypothetical protein NP_756095.1 4021144 D 199310 CDS NP_756096.1 26250056 1037009 4022319..4022813 1 NC_004431.1 Escherichia coli K-12 ortholog: b3443; hypothetical protein 4022813 yrhA 1037009 yrhA Escherichia coli CFT073 hypothetical protein NP_756096.1 4022319 D 199310 CDS NP_756097.1 26250057 1036992 4023263..4023547 1 NC_004431.1 Escherichia coli K-12 ortholog: b3446; hypothetical protein 4023547 yrhB 1036992 yrhB Escherichia coli CFT073 hypothetical protein NP_756097.1 4023263 D 199310 CDS NP_756098.1 26250058 1036970 complement(4023585..4025318) 1 NC_004431.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 4025318 ggt 1036970 ggt Escherichia coli CFT073 gamma-glutamyltranspeptidase NP_756098.1 4023585 R 199310 CDS NP_756099.1 26250059 1036972 4025438..4025878 1 NC_004431.1 ORFQ; Escherichia coli K-12 ortholog: b3448; Escherichia coli O157:H7 ortholog: z4815; hypothetical protein 4025878 yhhA 1036972 yhhA Escherichia coli CFT073 hypothetical protein NP_756099.1 4025438 D 199310 CDS NP_756100.1 26250060 1036999 complement(4025865..4026608) 1 NC_004431.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 4026608 ugpQ 1036999 ugpQ Escherichia coli CFT073 cytoplasmic glycerophosphodiester phosphodiesterase NP_756100.1 4025865 R 199310 CDS NP_756101.2 161486084 1037016 complement(4026605..4027675) 1 NC_004431.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 4027675 ugpC 1037016 ugpC Escherichia coli CFT073 glycerol-3-phosphate transporter ATP-binding subunit NP_756101.2 4026605 R 199310 CDS NP_756102.1 26250062 1036988 complement(4027677..4028522) 1 NC_004431.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4028522 ugpE 1036988 ugpE Escherichia coli CFT073 glycerol-3-phosphate transporter membrane protein NP_756102.1 4027677 R 199310 CDS NP_756103.1 26250063 1037034 complement(4028519..4029406) 1 NC_004431.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4029406 ugpA 1037034 ugpA Escherichia coli CFT073 glycerol-3-phosphate transporter permease NP_756103.1 4028519 R 199310 CDS NP_756104.1 26250064 1037036 complement(4029504..4030820) 1 NC_004431.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 4030820 ugpB 1037036 ugpB Escherichia coli CFT073 glycerol-3-phosphate transporter periplasmic binding protein NP_756104.1 4029504 R 199310 CDS NP_756105.1 26250065 1037018 4031097..4031228 1 NC_004431.1 hypothetical protein 4031228 1037018 c4243 Escherichia coli CFT073 hypothetical protein NP_756105.1 4031097 D 199310 CDS NP_756106.2 161486083 1037002 complement(4031217..4031930) 1 NC_004431.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4031930 livF 1037002 livF Escherichia coli CFT073 leucine/isoleucine/valine transporter ATP-binding subunit NP_756106.2 4031217 R 199310 CDS NP_756107.1 26250067 1036995 complement(4031932..4032699) 1 NC_004431.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4032699 livG 1036995 livG Escherichia coli CFT073 leucine/isoleucine/valine transporter ATP-binding subunit NP_756107.1 4031932 R 199310 CDS NP_756108.1 26250068 1036993 complement(4032696..4033973) 1 NC_004431.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 4033973 livM 1036993 livM Escherichia coli CFT073 leucine/isoleucine/valine transporter permease subunit NP_756108.1 4032696 R 199310 CDS NP_756109.1 26250069 1037053 complement(4033970..4034896) 1 NC_004431.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 4034896 livH 1037053 livH Escherichia coli CFT073 branched-chain amino acid transporter permease subunit LivH NP_756109.1 4033970 R 199310 CDS NP_756110.1 26250070 1037043 complement(4034944..4036107) 1 NC_004431.1 LS-BP; Escherichia coli K-12 ortholog: b3458; Escherichia coli O157:H7 ortholog: z4829; leucine-specific binding protein 4036107 livK 1037043 livK Escherichia coli CFT073 leucine-specific binding protein NP_756110.1 4034944 R 199310 CDS NP_756111.1 26250071 1037054 4036080..4036226 1 NC_004431.1 hypothetical protein 4036226 1037054 c4249 Escherichia coli CFT073 hypothetical protein NP_756111.1 4036080 D 199310 CDS NP_756112.1 26250072 1037055 complement(4036205..4036342) 1 NC_004431.1 hypothetical protein 4036342 1037055 c4250 Escherichia coli CFT073 hypothetical protein NP_756112.1 4036205 R 199310 CDS NP_756113.1 26250073 1037022 4036477..4036860 1 NC_004431.1 Escherichia coli K-12 ortholog: b3459; Escherichia coli O157:H7 ortholog: z4831; hypothetical protein 4036860 yhhK 1037022 yhhK Escherichia coli CFT073 hypothetical protein NP_756113.1 4036477 D 199310 CDS NP_756114.1 26250074 1037083 4036870..4036992 1 NC_004431.1 Residues 4 to 40 of 40 are 91.89 pct identical to residues 134 to 170 of 170 from GenPept.129 : >gb|AAA83882.1| (J05516) ORF19; [Escherichia coli]; hypothetical protein 4036992 1037083 c4252 Escherichia coli CFT073 hypothetical protein NP_756114.1 4036870 D 199310 CDS NP_756115.1 26250075 1037007 complement(4037048..4038208) 1 NC_004431.1 LIV-BP; Escherichia coli K-12 ortholog: b3460; Escherichia coli O157:H7 ortholog: z4834; Leu/Ile/Val-binding protein 4038208 livJ 1037007 livJ Escherichia coli CFT073 Leu/Ile/Val-binding protein NP_756115.1 4037048 R 199310 CDS NP_756116.1 26250076 1037023 complement(4038422..4039276) 1 NC_004431.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4039276 rpoH 1037023 rpoH Escherichia coli CFT073 RNA polymerase factor sigma-32 NP_756116.1 4038422 R 199310 CDS NP_756117.2 161486082 1037013 complement(4039521..4040579) 1 NC_004431.1 ABC transporter, membrane protein; cell division protein FtsX 4040579 ftsX 1037013 ftsX Escherichia coli CFT073 cell division protein FtsX NP_756117.2 4039521 R 199310 CDS NP_756118.1 26250078 1037070 complement(4040572..4041240) 1 NC_004431.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4041240 ftsE 1037070 ftsE Escherichia coli CFT073 cell division protein FtsE NP_756118.1 4040572 R 199310 CDS NP_756119.1 26250079 1037073 complement(4041243..4042739) 1 NC_004431.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 4042739 ftsY 1037073 ftsY Escherichia coli CFT073 cell division protein FtsY NP_756119.1 4041243 R 199310 CDS NP_756120.1 26250080 1037074 4042889..4043485 1 NC_004431.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4043485 rsmD 1037074 rsmD Escherichia coli CFT073 16S rRNA m(2)G966-methyltransferase NP_756120.1 4042889 D 199310 CDS NP_756121.1 26250081 1037056 4043472..4043744 1 NC_004431.1 Escherichia coli K-12 ortholog: b3466; Escherichia coli O157:H7 ortholog: z4840; hypothetical protein 4043744 yhhL 1037056 yhhL Escherichia coli CFT073 hypothetical protein NP_756121.1 4043472 D 199310 CDS NP_756122.1 26250082 1037072 complement(4043747..4044106) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3467; Escherichia coli O157:H7 ortholog: z4841; hypothetical protein 4044106 yhhM 1037072 yhhM Escherichia coli CFT073 hypothetical protein NP_756122.1 4043747 R 199310 CDS NP_756123.1 26250083 1037045 4044247..4044873 1 NC_004431.1 Escherichia coli K-12 ortholog: b3468; Escherichia coli O157:H7 ortholog: z4842; hypothetical protein 4044873 yhhN 1037045 yhhN Escherichia coli CFT073 hypothetical protein NP_756123.1 4044247 D 199310 CDS NP_756124.1 26250084 1037032 4044947..4047145 1 NC_004431.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4047145 zntA 1037032 zntA Escherichia coli CFT073 zinc/cadmium/mercury/lead-transporting ATPase NP_756124.1 4044947 D 199310 CDS NP_756125.1 26250085 1037050 complement(4047406..4047651) 1 NC_004431.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4047651 yhhP 1037050 yhhP Escherichia coli CFT073 sulfur transfer protein SirA NP_756125.1 4047406 R 199310 CDS NP_756126.1 26250086 1037075 4047872..4048537 1 NC_004431.1 Escherichia coli K-12 ortholog: b3471; Escherichia coli O157:H7 ortholog: z4845; hypothetical protein 4048537 yhhQ 1037075 yhhQ Escherichia coli CFT073 hypothetical protein NP_756126.1 4047872 D 199310 CDS NP_756127.2 161486081 1037095 4048610..4049167 1 NC_004431.1 Escherichia coli K-12 ortholog: b3472; Escherichia coli O157:H7 ortholog: z4846; hypothetical protein 4049167 1037095 c4265 Escherichia coli CFT073 hypothetical protein NP_756127.2 4048610 D 199310 CDS NP_756128.2 161486080 1037064 complement(4049171..4050388) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3473; Escherichia coli O157:H7 ortholog: z4847; major facilitator superfamily transporter 4050388 yhhS 1037064 yhhS Escherichia coli CFT073 major facilitator superfamily transporter NP_756128.2 4049171 R 199310 CDS NP_756129.1 26250089 1037123 4050439..4051569 1 NC_004431.1 Escherichia coli K-12 ortholog: b3474; Escherichia coli O157:H7 ortholog: z4848; hypothetical protein 4051569 yhhT 1037123 yhhT Escherichia coli CFT073 hypothetical protein NP_756129.1 4050439 D 199310 CDS NP_756130.1 26250090 1037124 4051624..4052211 1 NC_004431.1 Escherichia coli K-12 ortholog: b3475; Escherichia coli O157:H7 ortholog: z4867; holo-(acyl carrier protein) synthase 2 4052211 yhhU 1037124 yhhU Escherichia coli CFT073 holo-(acyl carrier protein) synthase 2 NP_756130.1 4051624 D 199310 CDS NP_756131.1 26250091 1037086 4052322..4053896 1 NC_004431.1 Escherichia coli K-12 ortholog: b3476; Escherichia coli O157:H7 ortholog: z4868; nickel-binding periplasmic protein 4053896 nikA 1037086 nikA Escherichia coli CFT073 nickel-binding periplasmic protein NP_756131.1 4052322 D 199310 CDS NP_756132.1 26250092 1037079 4053896..4054840 1 NC_004431.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4054840 nikB 1037079 nikB Escherichia coli CFT073 nickel transporter permease NikB NP_756132.1 4053896 D 199310 CDS NP_756133.1 26250093 1037069 4054837..4055670 1 NC_004431.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4055670 nikC 1037069 nikC Escherichia coli CFT073 nickel transporter permease NikC NP_756133.1 4054837 D 199310 CDS NP_756134.1 26250094 1037139 4055670..4056434 1 NC_004431.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4056434 nikD 1037139 nikD Escherichia coli CFT073 nickel transporter ATP-binding protein NikD NP_756134.1 4055670 D 199310 CDS NP_756135.1 26250095 1037104 4056431..4057237 1 NC_004431.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4057237 nikE 1037104 nikE Escherichia coli CFT073 nickel transporter ATP-binding protein NikE NP_756135.1 4056431 D 199310 CDS NP_756136.1 26250096 1037108 4057243..4057644 1 NC_004431.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4057644 yhhG 1037108 yhhG Escherichia coli CFT073 nickel responsive regulator NP_756136.1 4057243 D 199310 CDS NP_756137.1 26250097 1037082 complement(4057486..4057617) 1 NC_004431.1 hypothetical protein 4057617 1037082 c4275 Escherichia coli CFT073 hypothetical protein NP_756137.1 4057486 R 199310 CDS NP_756138.1 26250098 1037136 4057834..4058589 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4874; regulator 4058589 1037136 c4276 Escherichia coli CFT073 regulator NP_756138.1 4057834 D 199310 CDS NP_756139.1 26250099 1037132 4058602..4059087 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4875; phosphotransferase system enzyme subunit 4059087 1037132 c4277 Escherichia coli CFT073 phosphotransferase system enzyme subunit NP_756139.1 4058602 D 199310 CDS NP_756140.1 26250100 1037097 4059084..4059365 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4876; phosphotransferase system enzyme subunit 4059365 1037097 c4278 Escherichia coli CFT073 phosphotransferase system enzyme subunit NP_756140.1 4059084 D 199310 CDS NP_756141.1 26250101 1037116 4059412..4060800 1 NC_004431.1 EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z4877; PTS system, galactitol-specific IIC component 4060800 1037116 c4279 Escherichia coli CFT073 PTS system, galactitol-specific IIC component NP_756141.1 4059412 D 199310 CDS NP_756142.1 26250102 1037147 4060793..4062241 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4878; xylulose kinase 4062241 1037147 c4280 Escherichia coli CFT073 xylulose kinase NP_756142.1 4060793 D 199310 CDS NP_756143.1 26250103 1037143 complement(4062119..4062514) 1 NC_004431.1 hypothetical protein 4062514 1037143 c4281 Escherichia coli CFT073 hypothetical protein NP_756143.1 4062119 R 199310 CDS NP_756144.1 26250104 1037149 4062169..4062300 1 NC_004431.1 Residues 1 to 43 of 43 are 95.34 pct identical to residues 460 to 502 of 502 from GenPept.129 : >gb|AAG58613.1|AE005572_11 (AE005572) xylulose kinase [Escherichia coli O157:H7 EDL933]; hypothetical protein 4062300 1037149 c4282 Escherichia coli CFT073 hypothetical protein NP_756144.1 4062169 D 199310 CDS NP_756145.1 26250105 1037150 4062290..4062559 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4879; phosphocarrier protein 4062559 1037150 c4283 Escherichia coli CFT073 phosphocarrier protein NP_756145.1 4062290 D 199310 CDS NP_756146.1 26250106 1037131 4062591..4063442 1 NC_004431.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4063442 gatY 1037131 gatY Escherichia coli CFT073 fructose-1,6-bisphosphate aldolase NP_756146.1 4062591 D 199310 CDS NP_756147.1 26250107 1037134 complement(4063552..4064760) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3485; Escherichia coli O157:H7 ortholog: z4884; hypothetical protein 4064760 yhhJ 1037134 yhhJ Escherichia coli CFT073 hypothetical protein NP_756147.1 4063552 R 199310 CDS NP_756148.1 26250108 1037117 complement(4064676..4067411) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3486; Escherichia coli O157:H7 ortholog: z4885; ABC transporter ATP-binding protein 4067411 yhiH 1037117 yhiH Escherichia coli CFT073 ABC transporter ATP-binding protein NP_756148.1 4064676 R 199310 CDS NP_756149.1 26250109 1037127 complement(4067408..4068475) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3487; Escherichia coli O157:H7 ortholog: z4886; hypothetical protein 4068475 yhiI 1037127 yhiI Escherichia coli CFT073 hypothetical protein NP_756149.1 4067408 R 199310 CDS NP_756150.1 26250110 1037126 complement(4068468..4068599) 1 NC_004431.1 hypothetical protein 4068599 1037126 c4288 Escherichia coli CFT073 hypothetical protein NP_756150.1 4068468 R 199310 CDS NP_756151.1 26250111 1037157 4069197..4070261 1 NC_004431.1 Escherichia coli K-12 ortholog: b3491; Escherichia coli O157:H7 ortholog: z4890; hypothetical protein 4070261 yhiM 1037157 yhiM Escherichia coli CFT073 hypothetical protein NP_756151.1 4069197 D 199310 CDS NP_756152.1 26250112 1037159 complement(4070348..4071541) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3492; Escherichia coli O157:H7 ortholog: z4891; hypothetical protein 4071541 yhiN 1037159 yhiN Escherichia coli CFT073 hypothetical protein NP_756152.1 4070348 R 199310 CDS NP_756153.1 26250113 1037160 4071773..4073272 1 NC_004431.1 Escherichia coli K-12 ortholog: b3493; Escherichia coli O157:H7 ortholog: z4893; inorganic phosphate transporter 4073272 pitA 1037160 pitA Escherichia coli CFT073 inorganic phosphate transporter NP_756153.1 4071773 D 199310 CDS NP_756154.1 26250114 1037161 complement(4073343..4073678) 1 NC_004431.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4073678 yhiO 1037161 yhiO Escherichia coli CFT073 universal stress protein UspB NP_756154.1 4073343 R 199310 CDS NP_756155.1 26250115 1037151 4074069..4074503 1 NC_004431.1 Escherichia coli K-12 ortholog: b3495; Escherichia coli O157:H7 ortholog: z4895; universal stress protein A 4074503 uspA 1037151 uspA Escherichia coli CFT073 universal stress protein A NP_756155.1 4074069 D 199310 CDS NP_756156.1 26250116 1037171 complement(4074686..4074865) 1 NC_004431.1 hypothetical protein 4074865 1037171 c4294 Escherichia coli CFT073 hypothetical protein NP_756156.1 4074686 R 199310 CDS NP_756157.1 26250117 1037146 4074820..4076289 1 NC_004431.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4076289 yhiP 1037146 yhiP Escherichia coli CFT073 inner membrane transporter YhiP NP_756157.1 4074820 D 199310 CDS NP_756158.2 161486079 1037144 complement(4076338..4077090) 1 NC_004431.1 predicted SAM-dependent methyltransferase; methyltransferase 4077090 yhiQ 1037144 yhiQ Escherichia coli CFT073 methyltransferase NP_756158.2 4076338 R 199310 CDS NP_756159.1 26250119 1037168 complement(4077098..4079179) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3498; Escherichia coli O157:H7 ortholog: z4898; oligopeptidase A 4079179 prlC 1037168 prlC Escherichia coli CFT073 oligopeptidase A NP_756159.1 4077098 R 199310 CDS NP_756160.1 26250120 1037164 4079292..4080185 1 NC_004431.1 Escherichia coli K-12 ortholog: b3499; Escherichia coli O157:H7 ortholog: z4899; hypothetical protein 4080185 yhiR 1037164 yhiR Escherichia coli CFT073 hypothetical protein NP_756160.1 4079292 D 199310 CDS NP_756161.1 26250121 1037162 4080257..4081609 1 NC_004431.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4081609 gor 1037162 gor Escherichia coli CFT073 glutathione reductase NP_756161.1 4080257 D 199310 CDS NP_756162.1 26250122 1037167 complement(4081663..4081812) 1 NC_004431.1 hypothetical protein 4081812 1037167 c4300 Escherichia coli CFT073 hypothetical protein NP_756162.1 4081663 R 199310 CDS NP_756163.1 26250123 1037172 4082081..4082506 1 NC_004431.1 Escherichia coli K-12 ortholog: b3503; Escherichia coli O157:H7 ortholog: z4905; arsenate reductase 4082506 arsC 1037172 arsC Escherichia coli CFT073 arsenate reductase NP_756163.1 4082081 D 199310 CDS NP_756164.1 26250124 1037152 4082560..4082724 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4906; hypothetical protein 4082724 1037152 c4302 Escherichia coli CFT073 hypothetical protein NP_756164.1 4082560 D 199310 CDS NP_756165.1 26250125 1037154 4083123..4083296 1 NC_004431.1 Residues 1 to 53 of 57 are 86.79 pct identical to residues 1 to 53 of 260 from MG1655 : b3504; hypothetical protein 4083296 1037154 c4303 Escherichia coli CFT073 hypothetical protein NP_756165.1 4083123 D 199310 CDS NP_756166.1 26250126 1037175 4083657..4084256 1 NC_004431.1 Escherichia coli K-12 ortholog: b3506; Escherichia coli O157:H7 ortholog: z4908; outer membrane protein Slp 4084256 slp 1037175 slp Escherichia coli CFT073 outer membrane protein Slp NP_756166.1 4083657 D 199310 CDS NP_756167.1 26250127 1037176 4084297..4084470 1 NC_004431.1 hypothetical protein 4084470 1037176 c4305 Escherichia coli CFT073 hypothetical protein NP_756167.1 4084297 D 199310 CDS NP_756168.1 26250128 1037178 4084409..4084939 1 NC_004431.1 Escherichia coli K-12 ortholog: b3507; Escherichia coli O157:H7 ortholog: z4909; transcriptional regulator YhiF 4084939 yhiF 1037178 yhiF Escherichia coli CFT073 transcriptional regulator YhiF NP_756168.1 4084409 D 199310 CDS NP_756169.1 26250129 1037174 complement(4084996..4086024) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4910; heme/hemoglobin transport protein 4086024 chuS 1037174 chuS Escherichia coli CFT073 heme/hemoglobin transport protein NP_756169.1 4084996 R 199310 CDS NP_756170.1 26250130 1037196 complement(4086073..4088019) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4911; outer membrane heme/hemoglobin receptor 4088019 chuA 1037196 chuA Escherichia coli CFT073 outer membrane heme/hemoglobin receptor NP_756170.1 4086073 R 199310 CDS NP_756171.1 26250131 1037180 4087994..4088152 1 NC_004431.1 hypothetical protein 4088152 1037180 c4309 Escherichia coli CFT073 hypothetical protein NP_756171.1 4087994 D 199310 CDS NP_756172.1 26250132 1037163 complement(4088156..4088341) 1 NC_004431.1 hypothetical protein 4088341 1037163 c4310 Escherichia coli CFT073 hypothetical protein NP_756172.1 4088156 R 199310 CDS NP_756173.1 26250133 1037184 4088424..4088585 1 NC_004431.1 hypothetical protein 4088585 1037184 c4311 Escherichia coli CFT073 hypothetical protein NP_756173.1 4088424 D 199310 CDS NP_756174.1 26250134 1037192 complement(4088467..4088616) 1 NC_004431.1 Residues 1 to 48 of 49 are 79.16 pct identical to residues 1 to 48 of 94 from GenPept.129 : >gb|AAG58642.1|AE005576_1 (AE005576) Z4912 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 4088616 1037192 c4312 Escherichia coli CFT073 hypothetical protein NP_756174.1 4088467 R 199310 CDS NP_756175.1 26250135 1037179 4088661..4089653 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4913; periplasmic binding protein 4089653 chuT 1037179 chuT Escherichia coli CFT073 periplasmic binding protein NP_756175.1 4088661 D 199310 CDS NP_756176.1 26250136 1037191 4089673..4091010 1 NC_004431.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4091010 chuW 1037191 chuW Escherichia coli CFT073 coproporphyrinogen III oxidase NP_756176.1 4089673 D 199310 CDS NP_756177.1 26250137 1037205 4091023..4091517 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4915; hypothetical protein 4091517 chuX 1037205 chuX Escherichia coli CFT073 hypothetical protein NP_756177.1 4091023 D 199310 CDS NP_756178.1 26250138 1037194 4091517..4092140 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4917; hypothetical protein 4092140 chuY 1037194 chuY Escherichia coli CFT073 hypothetical protein NP_756178.1 4091517 D 199310 CDS NP_756179.1 26250139 1037170 4092189..4093181 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4918; iron ABC transporter permease 4093181 chuU 1037170 chuU Escherichia coli CFT073 iron ABC transporter permease NP_756179.1 4092189 D 199310 CDS NP_756180.1 26250140 1037200 4093148..4093948 1 NC_004431.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4093948 hmuV 1037200 hmuV Escherichia coli CFT073 hemin importer ATP-binding subunit NP_756180.1 4093148 D 199310 CDS NP_756181.1 26250141 1037199 complement(4094000..4094647) 1 NC_004431.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 4094647 yhiD 1037199 yhiD Escherichia coli CFT073 Mg(2+) transport ATPase NP_756181.1 4094000 R 199310 CDS NP_756182.1 26250142 1037197 complement(4094711..4095049) 1 NC_004431.1 10K-L protein; Escherichia coli K-12 ortholog: b3509; Escherichia coli O157:H7 ortholog: z4921; acid-resistance protein 4095049 hdeB 1037197 hdeB Escherichia coli CFT073 acid-resistance protein NP_756182.1 4094711 R 199310 CDS NP_756183.1 26250143 1037202 complement(4095153..4095485) 1 NC_004431.1 inactive form; acid-resistance protein 4095485 hdeA 1037202 hdeA Escherichia coli CFT073 acid-resistance protein NP_756183.1 4095153 R 199310 CDS NP_756184.1 26250144 1037203 4095740..4096312 1 NC_004431.1 Escherichia coli K-12 ortholog: b3511; Escherichia coli O157:H7 ortholog: z4923; acid-resistance membrane protein 4096312 hdeD 1037203 hdeD Escherichia coli CFT073 acid-resistance membrane protein NP_756184.1 4095740 D 199310 CDS NP_756185.1 26250145 1037206 4097033..4097638 1 NC_004431.1 Escherichia coli K-12 ortholog: b3512; Escherichia coli O157:H7 ortholog: z4925; hypothetical protein 4097638 yhiE 1037206 yhiE Escherichia coli CFT073 hypothetical protein NP_756185.1 4097033 D 199310 CDS NP_756186.1 26250146 1037183 4097977..4099134 1 NC_004431.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4099134 yhiU 1037183 yhiU Escherichia coli CFT073 multidrug efflux system protein MdtE NP_756186.1 4097977 D 199310 CDS NP_756187.1 26250147 1037186 4099159..4102272 1 NC_004431.1 Escherichia coli K-12 ortholog: b3514; Escherichia coli O157:H7 ortholog: z4927; hypothetical protein 4102272 yhiV 1037186 yhiV Escherichia coli CFT073 hypothetical protein NP_756187.1 4099159 D 199310 CDS NP_756188.1 26250148 1037214 complement(4102635..4103363) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3515; Escherichia coli O157:H7 ortholog: z4928; transcriptional regulator YhiW 4103363 yhiW 1037214 yhiW Escherichia coli CFT073 transcriptional regulator YhiW NP_756188.1 4102635 R 199310 CDS NP_756189.1 26250149 1037207 complement(4103732..4104556) 1 NC_004431.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 4104556 yhiX 1037207 yhiX Escherichia coli CFT073 DNA-binding transcriptional regulator GadX NP_756189.1 4103732 R 199310 CDS NP_756190.1 26250150 1037216 complement(4104924..4106387) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3517; Escherichia coli O157:H7 ortholog: z4930; glutamate decarboxylase alpha 4106387 gadA 1037216 gadA Escherichia coli CFT073 glutamate decarboxylase alpha NP_756190.1 4104924 R 199310 CDS NP_756191.1 26250151 1037210 complement(4106535..4107932) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3518; Escherichia coli O157:H7 ortholog: z4931; cytochrome C peroxidase 4107932 yhjA 1037210 yhjA Escherichia coli CFT073 cytochrome C peroxidase NP_756191.1 4106535 R 199310 CDS NP_756192.1 26250152 1037213 4108337..4109986 1 NC_004431.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4109986 treF 1037213 treF Escherichia coli CFT073 trehalase NP_756192.1 4108337 D 199310 CDS NP_756193.1 26250153 1037230 complement(4110037..4110639) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3520; Escherichia coli O157:H7 ortholog: z4933; transcriptional regulator YhjB 4110639 yhjB 1037230 yhjB Escherichia coli CFT073 transcriptional regulator YhjB NP_756193.1 4110037 R 199310 CDS NP_756194.1 26250154 1037218 4111087..4112058 1 NC_004431.1 Escherichia coli K-12 ortholog: b3521; Escherichia coli O157:H7 ortholog: z4934; transcriptional regulator YhjC 4112058 yhjC 1037218 yhjC Escherichia coli CFT073 transcriptional regulator YhjC NP_756194.1 4111087 D 199310 CDS NP_756195.1 26250155 1037217 4112107..4113120 1 NC_004431.1 Escherichia coli K-12 ortholog: b3522; Escherichia coli O157:H7 ortholog: z4935; hypothetical protein 4113120 yhjD 1037217 yhjD Escherichia coli CFT073 hypothetical protein NP_756195.1 4112107 D 199310 CDS NP_756196.1 26250156 1037229 4113513..4114835 1 NC_004431.1 Escherichia coli K-12 ortholog: b3523; Escherichia coli O157:H7 ortholog: z4936; metabolite transport protein 4114835 yhjE 1037229 yhjE Escherichia coli CFT073 metabolite transport protein NP_756196.1 4113513 D 199310 CDS NP_756197.1 26250157 1037239 complement(4115014..4117089) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3524; Escherichia coli O157:H7 ortholog: z4937; hypothetical protein 4117089 yhjG 1037239 yhjG Escherichia coli CFT073 hypothetical protein NP_756197.1 4115014 R 199310 CDS NP_756198.1 26250158 1037219 complement(4117144..4117914) 1 NC_004431.1 in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase 4117914 yhjH 1037219 yhjH Escherichia coli CFT073 diguanylate phosphodiesterase NP_756198.1 4117144 R 199310 CDS NP_756199.1 26250159 1037228 4117795..4119072 1 NC_004431.1 Escherichia coli K-12 ortholog: b3526; Escherichia coli O157:H7 ortholog: z4940; 2-dehydro-3-deoxygluconokinase 4119072 kdgK 1037228 kdgK Escherichia coli CFT073 2-dehydro-3-deoxygluconokinase NP_756199.1 4117795 D 199310 CDS YP_004853828.1 347357944 1037261 4117880..4118059 1 NC_004431.1 hypothetical protein 4118059 1037261 c4338 Escherichia coli CFT073 hypothetical protein YP_004853828.1 4117880 D 199310 CDS NP_756201.1 26250161 1037241 complement(4119168..4120664) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3527; Escherichia coli O157:H7 ortholog: z4941; hypothetical protein 4120664 yhjJ 1037241 yhjJ Escherichia coli CFT073 hypothetical protein NP_756201.1 4119168 R 199310 CDS NP_756202.1 26250162 1037204 complement(4120884..4122170) 1 NC_004431.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4122170 dctA 1037204 dctA Escherichia coli CFT073 C4-dicarboxylate transporter DctA NP_756202.1 4120884 R 199310 CDS NP_756203.2 229106368 1037258 complement(4122353..4124308) 1 NC_004431.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase 4124308 yhjK 1037258 yhjK Escherichia coli CFT073 phosphodiesterase NP_756203.2 4122353 R 199310 CDS NP_756204.1 26250164 1037248 complement(4124423..4127896) 1 NC_004431.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 4127896 yhjL 1037248 yhjL Escherichia coli CFT073 cellulose synthase subunit BcsC NP_756204.1 4124423 R 199310 CDS NP_756205.1 26250165 1037238 complement(4127878..4128990) 1 NC_004431.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4128990 yhjM 1037238 yhjM Escherichia coli CFT073 endo-1,4-D-glucanase NP_756205.1 4127878 R 199310 CDS NP_756206.1 26250166 1037255 complement(4128991..4131417) 1 NC_004431.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4131417 yhjN 1037255 yhjN Escherichia coli CFT073 cellulose synthase regulator protein NP_756206.1 4128991 R 199310 CDS NP_756207.2 161486078 1037224 complement(4131341..4133959) 1 NC_004431.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 4133959 bcsA 1037224 bcsA Escherichia coli CFT073 cellulose synthase catalytic subunit NP_756207.2 4131341 R 199310 CDS NP_756208.1 26250168 1037280 complement(4133956..4134708) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3534; Escherichia coli O157:H7 ortholog: z4949; cell division protein 4134708 yhjQ 1037280 yhjQ Escherichia coli CFT073 cell division protein NP_756208.1 4133956 R 199310 CDS NP_756209.1 26250169 1037221 complement(4134720..4134908) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3535; Escherichia coli O157:H7 ortholog: z4951; hypothetical protein 4134908 yhjR 1037221 yhjR Escherichia coli CFT073 hypothetical protein NP_756209.1 4134720 R 199310 CDS NP_756210.1 26250170 1037291 4135181..4136752 1 NC_004431.1 Escherichia coli K-12 ortholog: b3536; Escherichia coli O157:H7 ortholog: z4952; hypothetical protein 4136752 yhjS 1037291 yhjS Escherichia coli CFT073 hypothetical protein NP_756210.1 4135181 D 199310 CDS NP_756211.1 26250171 1037282 4136749..4136940 1 NC_004431.1 Escherichia coli K-12 ortholog: b3537; Escherichia coli O157:H7 ortholog: z4953; hypothetical protein 4136940 yhjT 1037282 yhjT Escherichia coli CFT073 hypothetical protein NP_756211.1 4136749 D 199310 CDS NP_756212.1 26250172 1037263 4136937..4138616 1 NC_004431.1 Escherichia coli K-12 ortholog: b3538; Escherichia coli O157:H7 ortholog: z4954; hypothetical protein 4138616 yhjU 1037263 yhjU Escherichia coli CFT073 hypothetical protein NP_756212.1 4136937 D 199310 CDS NP_756213.1 26250173 1037288 complement(4138702..4138944) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4955; hypothetical protein 4138944 1037288 c4351 Escherichia coli CFT073 hypothetical protein NP_756213.1 4138702 R 199310 CDS NP_756214.1 26250174 1037352 4139049..4139240 1 NC_004431.1 hypothetical protein 4139240 1037352 c4352 Escherichia coli CFT073 hypothetical protein NP_756214.1 4139049 D 199310 CDS NP_756215.1 26250175 1037292 complement(4139457..4139618) 1 NC_004431.1 hypothetical protein 4139618 1037292 c4353 Escherichia coli CFT073 hypothetical protein NP_756215.1 4139457 R 199310 CDS NP_756216.1 26250176 1037313 4139705..4141039 1 NC_004431.1 Escherichia coli K-12 ortholog: b3539; Escherichia coli O157:H7 ortholog: z4956; transport protein YhjV 4141039 yhjV 1037313 yhjV Escherichia coli CFT073 transport protein YhjV NP_756216.1 4139705 D 199310 CDS NP_756217.1 26250177 1037240 complement(4141069..4142073) 1 NC_004431.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4142073 dppF 1037240 dppF Escherichia coli CFT073 dipeptide transporter ATP-binding subunit NP_756217.1 4141069 R 199310 CDS NP_756218.1 26250178 1037319 complement(4142070..4143053) 1 NC_004431.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4143053 dppD 1037319 dppD Escherichia coli CFT073 dipeptide transporter ATP-binding subunit NP_756218.1 4142070 R 199310 CDS NP_756219.1 26250179 1037340 complement(4143064..4143966) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3542; Escherichia coli O157:H7 ortholog: z4959; dipeptide transporter 4143966 dppC 1037340 dppC Escherichia coli CFT073 dipeptide transporter NP_756219.1 4143064 R 199310 CDS NP_756220.1 26250180 1037294 complement(4143976..4144995) 1 NC_004431.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4144995 dppB 1037294 dppB Escherichia coli CFT073 dipeptide transporter permease DppB NP_756220.1 4143976 R 199310 CDS YP_004853829.1 347357945 1037327 4144958..4145329 1 NC_004431.1 hypothetical protein 4145329 1037327 c4359 Escherichia coli CFT073 hypothetical protein YP_004853829.1 4144958 D 199310 CDS YP_004853830.1 347357946 1037329 4145013..4145240 1 NC_004431.1 hypothetical protein 4145240 1037329 c4360 Escherichia coli CFT073 hypothetical protein YP_004853830.1 4145013 D 199310 CDS NP_756223.1 26250183 1037335 complement(4145302..4146909) 1 NC_004431.1 Dipeptide-binding protein; Escherichia coli K-12 ortholog: b3544; Escherichia coli O157:H7 ortholog: z4961; periplasmic dipeptide transport protein 4146909 dppA 1037335 dppA Escherichia coli CFT073 periplasmic dipeptide transport protein NP_756223.1 4145302 R 199310 CDS YP_004853831.1 347357947 1037350 4147098..4147253 1 NC_004431.1 hypothetical protein 4147253 1037350 c4362 Escherichia coli CFT073 hypothetical protein YP_004853831.1 4147098 D 199310 CDS YP_004853832.1 347357917 1037277 complement(4147261..4147770) 1 NC_004431.1 hypothetical protein 4147770 1037277 c4363 Escherichia coli CFT073 hypothetical protein YP_004853832.1 4147261 R 199310 CDS NP_756226.2 161486077 1037384 complement(4147821..4149512) 1 NC_004431.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4149512 yhjW 1037384 yhjW Escherichia coli CFT073 phosphoethanolamine transferase NP_756226.2 4147821 R 199310 CDS NP_756227.1 26250187 1037374 complement(4149836..4151044) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3547; Escherichia coli O157:H7 ortholog: z4972; hypothetical protein 4151044 yhjX 1037374 yhjX Escherichia coli CFT073 hypothetical protein NP_756227.1 4149836 R 199310 CDS NP_756228.1 26250188 1037375 complement(4151273..4151977) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3548; Escherichia coli O157:H7 ortholog: z4973; hypothetical protein 4151977 yhjY 1037375 yhjY Escherichia coli CFT073 hypothetical protein NP_756228.1 4151273 R 199310 CDS NP_756229.2 161486076 1037396 4152129..4152692 1 NC_004431.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4152692 tag 1037396 tag Escherichia coli CFT073 3-methyl-adenine DNA glycosylase I NP_756229.2 4152129 D 199310 CDS NP_756230.1 26250190 1037389 4152689..4153129 1 NC_004431.1 Escherichia coli K-12 ortholog: b3550; Escherichia coli O157:H7 ortholog: z4975; hypothetical protein 4153129 yiaC 1037389 yiaC Escherichia coli CFT073 hypothetical protein NP_756230.1 4152689 D 199310 CDS NP_756231.1 26250191 1037312 complement(4153098..4155431) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3551; Escherichia coli O157:H7 ortholog: z4976; biotin sulfoxide reductase 4155431 bisC 1037312 bisC Escherichia coli CFT073 biotin sulfoxide reductase NP_756231.1 4153098 R 199310 CDS NP_756232.1 26250192 1037473 4155584..4156243 1 NC_004431.1 Escherichia coli K-12 ortholog: b3552; Escherichia coli O157:H7 ortholog: z4977; outer membrane lipoprotein 4156243 yiaD 1037473 yiaD Escherichia coli CFT073 outer membrane lipoprotein NP_756232.1 4155584 D 199310 CDS NP_756233.1 26250193 1037439 4156259..4156384 1 NC_004431.1 hypothetical protein 4156384 1037439 c4371 Escherichia coli CFT073 hypothetical protein NP_756233.1 4156259 D 199310 CDS NP_756234.2 161486075 1037406 4156347..4157321 1 NC_004431.1 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 4157321 yiaE 1037406 yiaE Escherichia coli CFT073 2-hydroxyacid dehydrogenase NP_756234.2 4156347 D 199310 CDS NP_756235.1 26250195 1037397 complement(4157371..4158201) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3554; Escherichia coli O157:H7 ortholog: z4979; hypothetical protein 4158201 yiaF 1037397 yiaF Escherichia coli CFT073 hypothetical protein NP_756235.1 4157371 R 199310 CDS NP_756236.1 26250196 1037392 4158236..4158385 1 NC_004431.1 hypothetical protein 4158385 1037392 c4374 Escherichia coli CFT073 hypothetical protein NP_756236.1 4158236 D 199310 CDS NP_756237.1 26250197 1037386 4158515..4158805 1 NC_004431.1 Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980; transcriptional regulator 4158805 1037386 c4375 Escherichia coli CFT073 transcriptional regulator NP_756237.1 4158515 D 199310 CDS NP_756238.1 26250198 1037437 complement(4159023..4159385) 1 NC_004431.1 hypothetical protein 4159385 1037437 c4376 Escherichia coli CFT073 hypothetical protein NP_756238.1 4159023 R 199310 CDS NP_756239.1 26250199 1037378 4159086..4159298 1 NC_004431.1 CSP-A; Escherichia coli K-12 ortholog: b3556; Escherichia coli O157:H7 ortholog: z4981; major cold shock protein 4159298 cspA 1037378 cspA Escherichia coli CFT073 major cold shock protein NP_756239.1 4159086 D 199310 CDS NP_756240.1 26250200 1037405 complement(4159961..4162030) 1 NC_004431.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4162030 glyS 1037405 glyS Escherichia coli CFT073 glycyl-tRNA synthetase subunit beta NP_756240.1 4159961 R 199310 CDS NP_756241.1 26250201 1037440 complement(4162040..4162951) 1 NC_004431.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4162951 glyQ 1037440 glyQ Escherichia coli CFT073 glycyl-tRNA synthetase subunit alpha NP_756241.1 4162040 R 199310 CDS NP_756242.1 26250202 1037562 complement(4163046..4163345) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z4985; hypothetical protein 4163345 1037562 c4380 Escherichia coli CFT073 hypothetical protein NP_756242.1 4163046 R 199310 CDS NP_756243.1 26250203 1037411 4163520..4164515 1 NC_004431.1 Escherichia coli K-12 ortholog: b3561; Escherichia coli O157:H7 ortholog: z4986; hypothetical protein 4164515 yiaH 1037411 yiaH Escherichia coli CFT073 hypothetical protein NP_756243.1 4163520 D 199310 CDS NP_756244.1 26250204 1037408 complement(4164557..4164997) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3562; Escherichia coli O157:H7 ortholog: z4987; hypothetical protein 4164997 yiaA 1037408 yiaA Escherichia coli CFT073 hypothetical protein NP_756244.1 4164557 R 199310 CDS NP_756245.1 26250205 1037566 complement(4165040..4165423) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3563; Escherichia coli O157:H7 ortholog: z4988; hypothetical protein 4165423 yiaB 1037566 yiaB Escherichia coli CFT073 hypothetical protein NP_756245.1 4165040 R 199310 CDS NP_756246.1 26250206 1037451 complement(4165550..4167004) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3564; Escherichia coli O157:H7 ortholog: z4989; xylulokinase 4167004 xylB 1037451 xylB Escherichia coli CFT073 xylulokinase NP_756246.1 4165550 R 199310 CDS NP_756247.2 161486074 1037435 complement(4167076..4168398) 1 NC_004431.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4168398 xylA 1037435 xylA Escherichia coli CFT073 xylose isomerase NP_756247.2 4167076 R 199310 CDS NP_756248.1 26250208 1037599 4168686..4169756 1 NC_004431.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4169756 xylF 1037599 xylF Escherichia coli CFT073 D-xylose transporter subunit XylF NP_756248.1 4168686 D 199310 CDS NP_756249.2 229106367 1037600 4169834..4171375 1 NC_004431.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4171375 xylG 1037600 xylG Escherichia coli CFT073 xylose transporter ATP-binding subunit NP_756249.2 4169834 D 199310 CDS NP_756250.1 26250210 1037602 4171353..4172534 1 NC_004431.1 Escherichia coli K-12 ortholog: b3568; Escherichia coli O157:H7 ortholog: z4993; xylose transport system permease xylH 4172534 xylH 1037602 xylH Escherichia coli CFT073 xylose transport system permease xylH NP_756250.1 4171353 D 199310 CDS NP_756251.1 26250211 1037569 4172612..4173790 1 NC_004431.1 Escherichia coli K-12 ortholog: b3569; Escherichia coli O157:H7 ortholog: z4994; xylose operon regulatory protein 4173790 xylR 1037569 xylR Escherichia coli CFT073 xylose operon regulatory protein NP_756251.1 4172612 D 199310 CDS NP_756252.1 26250212 1037612 complement(4173898..4174722) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3570; Escherichia coli O157:H7 ortholog: z4995; hypothetical protein 4174722 bax 1037612 bax Escherichia coli CFT073 hypothetical protein NP_756252.1 4173898 R 199310 CDS NP_756253.1 26250213 1037474 4174872..4175045 1 NC_004431.1 hypothetical protein 4175045 1037474 c4391 Escherichia coli CFT073 hypothetical protein NP_756253.1 4174872 D 199310 CDS NP_756254.1 26250214 1037563 4175042..4177072 1 NC_004431.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4177072 malS 1037563 malS Escherichia coli CFT073 periplasmic alpha-amylase NP_756254.1 4175042 D 199310 CDS NP_756255.2 161486073 1037603 4177250..4178503 1 NC_004431.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4178503 avtA 1037603 avtA Escherichia coli CFT073 valine--pyruvate transaminase NP_756255.2 4177250 D 199310 CDS NP_756256.1 26250216 1037610 complement(4178655..4179134) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3573; Escherichia coli O157:H7 ortholog: z4998; electron transport protein ysaA 4179134 yiaI 1037610 yiaI Escherichia coli CFT073 electron transport protein ysaA NP_756256.1 4178655 R 199310 CDS NP_756257.1 26250217 1037606 complement(4179230..4180078) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3574; Escherichia coli O157:H7 ortholog: z2874; transcriptional regulator YiaJ 4180078 yiaJ 1037606 yiaJ Escherichia coli CFT073 transcriptional regulator YiaJ NP_756257.1 4179230 R 199310 CDS NP_756258.1 26250218 1037613 4180279..4181277 1 NC_004431.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4181277 yiaK 1037613 yiaK Escherichia coli CFT073 2,3-diketo-L-gulonate reductase NP_756258.1 4180279 D 199310 CDS NP_756259.1 26250219 1037601 4181289..4181753 1 NC_004431.1 Escherichia coli K-12 ortholog: b3576; hypothetical protein 4181753 yiaL 1037601 yiaL Escherichia coli CFT073 hypothetical protein NP_756259.1 4181289 D 199310 CDS NP_756260.1 26250220 1037589 4181776..4182696 1 NC_004431.1 Residues 4 to 305 of 306 are 76.72 pct identical to residues 3 to 307 of 310 from GenPept.129 : >gb|AAL22529.1| (AE008870) chemotaxis protein, resembles cheA [Salmonella typhimurium LT2]; hypothetical protein 4182696 1037589 c4398 Escherichia coli CFT073 hypothetical protein NP_756260.1 4181776 D 199310 CDS NP_756261.1 26250221 1037597 4182810..4183277 1 NC_004431.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4183277 yiaM 1037597 yiaM Escherichia coli CFT073 2,3-diketo-L-gulonate TRAP transporter small permease YiaM NP_756261.1 4182810 D 199310 CDS NP_756262.1 26250222 1037621 4183280..4184557 1 NC_004431.1 Escherichia coli K-12 ortholog: b3578; hypothetical protein 4184557 yiaN 1037621 yiaN Escherichia coli CFT073 hypothetical protein NP_756262.1 4183280 D 199310 CDS NP_756263.1 26250223 1037617 4184545..4184667 1 NC_004431.1 hypothetical protein 4184667 1037617 c4401 Escherichia coli CFT073 hypothetical protein NP_756263.1 4184545 D 199310 CDS NP_756264.1 26250224 1037623 4184570..4185556 1 NC_004431.1 Escherichia coli K-12 ortholog: b3579; Escherichia coli O157:H7 ortholog: z1284; ABC transporter periplasmic-binding protein 4185556 yiaO 1037623 yiaO Escherichia coli CFT073 ABC transporter periplasmic-binding protein NP_756264.1 4184570 D 199310 CDS NP_756265.1 26250225 1037624 4185560..4187056 1 NC_004431.1 Escherichia coli K-12 ortholog: b3580; Cryptic L-xylulose kinase 4187056 lyxK 1037624 lyxK Escherichia coli CFT073 Cryptic L-xylulose kinase NP_756265.1 4185560 D 199310 CDS NP_756266.1 26250226 1037608 4187053..4187715 1 NC_004431.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4187715 sgbH 1037608 sgbH Escherichia coli CFT073 3-keto-L-gulonate-6-phosphate decarboxylase NP_756266.1 4187053 D 199310 CDS NP_756267.1 26250227 1037703 4187675..4188568 1 NC_004431.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4188568 sgbU 1037703 sgbU Escherichia coli CFT073 L-xylulose 5-phosphate 3-epimerase NP_756267.1 4187675 D 199310 CDS NP_756268.1 26250228 1037607 4188562..4189257 1 NC_004431.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4189257 sgbE 1037607 sgbE Escherichia coli CFT073 L-ribulose-5-phosphate 4-epimerase NP_756268.1 4188562 D 199310 CDS NP_756269.1 26250229 1037620 complement(4188565..4189302) 1 NC_004431.1 hypothetical protein 4189302 1037620 c4407 Escherichia coli CFT073 hypothetical protein NP_756269.1 4188565 R 199310 CDS NP_756270.1 26250230 1037660 complement(4189304..4190932) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3588; Escherichia coli O157:H7 ortholog: z5008; aldehyde dehydrogenase 4190932 aldB 1037660 aldB Escherichia coli CFT073 aldehyde dehydrogenase NP_756270.1 4189304 R 199310 CDS NP_756271.1 26250231 1037709 complement(4190950..4192245) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5009; hypothetical protein 4192245 1037709 c4409 Escherichia coli CFT073 hypothetical protein NP_756271.1 4190950 R 199310 CDS NP_756272.1 26250232 1037622 complement(4192375..4193526) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3589; Escherichia coli O157:H7 ortholog: z5010; alcohol dehydrogenase 4193526 yiaY 1037622 yiaY Escherichia coli CFT073 alcohol dehydrogenase NP_756272.1 4192375 R 199310 CDS NP_756273.1 26250233 1037611 complement(4193717..4195561) 1 NC_004431.1 SelB translation factor; Escherichia coli K-12 ortholog: b3590; Escherichia coli O157:H7 ortholog: z5011; selenocysteinyl-tRNA-specific translation factor 4195561 selB 1037611 selB Escherichia coli CFT073 selenocysteinyl-tRNA-specific translation factor NP_756273.1 4193717 R 199310 CDS NP_756274.1 26250234 1037619 complement(4195558..4196949) 1 NC_004431.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4196949 selA 1037619 selA Escherichia coli CFT073 selenocysteine synthase NP_756274.1 4195558 R 199310 CDS NP_756275.1 26250235 1037650 complement(4197047..4197655) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3592; Escherichia coli O157:H7 ortholog: z5013; glutathione S-transferase 4197655 yibF 1037650 yibF Escherichia coli CFT073 glutathione S-transferase NP_756275.1 4197047 R 199310 CDS NP_756276.1 26250236 1037871 complement(4197726..4198862) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3597; Escherichia coli O157:H7 ortholog: z5021; hypothetical protein 4198862 yibH 1037871 yibH Escherichia coli CFT073 hypothetical protein NP_756276.1 4197726 R 199310 CDS NP_756277.1 26250237 1037926 complement(4198865..4199227) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3598; Escherichia coli O157:H7 ortholog: z5022; hypothetical protein 4199227 yibI 1037926 yibI Escherichia coli CFT073 hypothetical protein NP_756277.1 4198865 R 199310 CDS NP_756278.1 26250238 1037930 4199764..4201677 1 NC_004431.1 EIIABC-MTL; Escherichia coli K-12 ortholog: b3599; Escherichia coli O157:H7 ortholog: z5023; PTS system, mannitol-specific IIABC component 4201677 mtlA 1037930 mtlA Escherichia coli CFT073 PTS system, mannitol-specific IIABC component NP_756278.1 4199764 D 199310 CDS NP_756279.1 26250239 1037857 4201917..4203245 1 NC_004431.1 Escherichia coli K-12 ortholog: b3600; Escherichia coli O157:H7 ortholog: z5024; mannitol-1-phosphate 5-dehydrogenase 4203245 mtlD 1037857 mtlD Escherichia coli CFT073 mannitol-1-phosphate 5-dehydrogenase NP_756279.1 4201917 D 199310 CDS NP_756280.1 26250240 1037649 4203245..4203832 1 NC_004431.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4203832 mtlR 1037649 mtlR Escherichia coli CFT073 mannitol repressor protein NP_756280.1 4203245 D 199310 CDS NP_756281.1 26250241 1037629 complement(4203843..4204052) 1 NC_004431.1 Residues 1 to 67 of 69 are 77.61 pct identical to residues 1 to 67 of 69 from GenPept.129 : >gb|AAL22547.1| (AE008871) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 4204052 1037629 c4419 Escherichia coli CFT073 hypothetical protein NP_756281.1 4203843 R 199310 CDS NP_756282.1 26250242 1038090 complement(4204255..4204665) 1 NC_004431.1 hypothetical protein 4204665 1038090 c4420 Escherichia coli CFT073 hypothetical protein NP_756282.1 4204255 R 199310 CDS NP_756283.1 26250243 1038097 4204336..4204698 1 NC_004431.1 Escherichia coli K-12 ortholog: b3602; Escherichia coli O157:H7 ortholog: z5026; hypothetical protein 4204698 yibL 1038097 yibL Escherichia coli CFT073 hypothetical protein NP_756283.1 4204336 D 199310 CDS NP_756284.1 26250244 1037859 complement(4204954..4205121) 1 NC_004431.1 hypothetical protein 4205121 1037859 c4422 Escherichia coli CFT073 hypothetical protein NP_756284.1 4204954 R 199310 CDS NP_756285.1 26250245 1037688 4205257..4205940 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5028; hypothetical protein 4205940 1037688 c4423 Escherichia coli CFT073 hypothetical protein NP_756285.1 4205257 D 199310 CDS NP_756286.1 26250246 1038067 4205984..4211320 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5029; adhesin 4211320 1038067 c4424 Escherichia coli CFT073 adhesin NP_756286.1 4205984 D 199310 CDS NP_756287.1 26250247 1037724 4211711..4213387 1 NC_004431.1 Escherichia coli K-12 ortholog: b3603; Escherichia coli O157:H7 ortholog: z5030; L-lactate permease 4213387 lldP 1037724 lldP Escherichia coli CFT073 L-lactate permease NP_756287.1 4211711 D 199310 CDS NP_756288.1 26250248 1038127 4213372..4214163 1 NC_004431.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4214163 lldR 1038127 lldR Escherichia coli CFT073 DNA-binding transcriptional repressor LldR NP_756288.1 4213372 D 199310 CDS NP_756289.1 26250249 1038129 4214160..4215350 1 NC_004431.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4215350 lldD 1038129 lldD Escherichia coli CFT073 L-lactate dehydrogenase NP_756289.1 4214160 D 199310 CDS NP_756290.1 26250250 1038081 4215398..4215871 1 NC_004431.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4215871 yibK 1038081 yibK Escherichia coli CFT073 tRNA/rRNA methyltransferase YibK NP_756290.1 4215398 D 199310 CDS NP_756291.1 26250251 1037917 complement(4215926..4216747) 1 NC_004431.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4216747 cysE 1037917 cysE Escherichia coli CFT073 serine acetyltransferase NP_756291.1 4215926 R 199310 CDS NP_756292.1 26250252 1038114 complement(4216827..4217846) 1 NC_004431.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4217846 gpsA 1038114 gpsA Escherichia coli CFT073 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_756292.1 4216827 R 199310 CDS NP_756293.1 26250253 1038087 4217825..4218310 1 NC_004431.1 Residues 12 to 161 of 161 are 95.33 pct identical to residues 1 to 150 of 150 from SwissProt.40 : >sp|P15041|YZSB_ECOLI VERY HYPOTHETICAL 17.7 KD PROTEIN IN SECB REGION; hypothetical protein 4218310 1038087 c4431 Escherichia coli CFT073 hypothetical protein NP_756293.1 4217825 D 199310 CDS NP_756294.2 161486072 1037860 complement(4217846..4218313) 1 NC_004431.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4218313 secB 1037860 secB Escherichia coli CFT073 preprotein translocase subunit SecB NP_756294.2 4217846 R 199310 CDS NP_756295.1 26250255 1038120 complement(4218377..4218628) 1 NC_004431.1 Grx3; Escherichia coli K-12 ortholog: b3610; Escherichia coli O157:H7 ortholog: z5037; glutaredoxin 3 4218628 grxC 1038120 grxC Escherichia coli CFT073 glutaredoxin 3 NP_756295.1 4218377 R 199310 CDS NP_756296.1 26250256 1038155 4218443..4218706 1 NC_004431.1 hypothetical protein 4218706 1038155 c4434 Escherichia coli CFT073 hypothetical protein NP_756296.1 4218443 D 199310 CDS NP_756297.1 26250257 1038118 complement(4218725..4218883) 1 NC_004431.1 hypothetical protein 4218883 1038118 c4435 Escherichia coli CFT073 hypothetical protein NP_756297.1 4218725 R 199310 CDS NP_756298.1 26250258 1038088 complement(4218769..4219212) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3611; Escherichia coli O157:H7 ortholog: z5038; hypothetical protein 4219212 yibN 1038088 yibN Escherichia coli CFT073 hypothetical protein NP_756298.1 4218769 R 199310 CDS NP_756299.1 26250259 1038178 4219224..4219421 1 NC_004431.1 hypothetical protein 4219421 1038178 c4437 Escherichia coli CFT073 hypothetical protein NP_756299.1 4219224 D 199310 CDS NP_756300.2 161486071 1038126 4219445..4220989 1 NC_004431.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4220989 yibO 1038126 yibO Escherichia coli CFT073 phosphoglyceromutase NP_756300.2 4219445 D 199310 CDS NP_756301.1 26250261 1038123 4220999..4222282 1 NC_004431.1 Escherichia coli K-12 ortholog: b3613; Escherichia coli O157:H7 ortholog: z5040; hypothetical protein 4222282 yibP 1038123 yibP Escherichia coli CFT073 hypothetical protein NP_756301.1 4220999 D 199310 CDS NP_756302.1 26250262 1038084 4222286..4223245 1 NC_004431.1 Escherichia coli K-12 ortholog: b3614; Escherichia coli O157:H7 ortholog: z5041; hypothetical protein 4223245 yibQ 1038084 yibQ Escherichia coli CFT073 hypothetical protein NP_756302.1 4222286 D 199310 CDS NP_756303.1 26250263 1038154 complement(4223232..4224266) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3615; Escherichia coli O157:H7 ortholog: z5042; glycosyl transferase 4224266 yibD 1038154 yibD Escherichia coli CFT073 glycosyl transferase NP_756303.1 4223232 R 199310 CDS NP_756304.1 26250264 1038208 4224496..4225521 1 NC_004431.1 hypothetical protein 4225521 1038208 c4442 Escherichia coli CFT073 hypothetical protein NP_756304.1 4224496 D 199310 CDS NP_756305.1 26250265 1038233 complement(4224505..4225530) 1 NC_004431.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4225530 tdh 1038233 tdh Escherichia coli CFT073 L-threonine 3-dehydrogenase NP_756305.1 4224505 R 199310 CDS NP_756306.1 26250266 1038222 complement(4225540..4226736) 1 NC_004431.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 4226736 kbl 1038222 kbl Escherichia coli CFT073 2-amino-3-ketobutyrate CoA ligase NP_756306.1 4225540 R 199310 CDS NP_756307.1 26250267 1038172 4226950..4227882 1 NC_004431.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4227882 rfaD 1038172 rfaD Escherichia coli CFT073 ADP-L-glycero-D-manno-heptose-6-epimerase NP_756307.1 4226950 D 199310 CDS NP_756308.1 26250268 1038150 4227892..4228938 1 NC_004431.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4228938 rfaF 1038150 rfaF Escherichia coli CFT073 ADP-heptose:LPS heptosyltransferase II NP_756308.1 4227892 D 199310 CDS NP_756309.1 26250269 1038145 4228942..4229922 1 NC_004431.1 Escherichia coli K-12 ortholog: b3621; Escherichia coli O157:H7 ortholog: z5048; ADP-heptose:LPS heptosyl transferase I 4229922 rfaC 1038145 rfaC Escherichia coli CFT073 ADP-heptose:LPS heptosyl transferase I NP_756309.1 4228942 D 199310 CDS NP_756310.1 26250270 1038237 complement(4229992..4231245) 1 NC_004431.1 Residues 1 to 417 of 417 are 96.40 pct identical to residues 1 to 417 of 417 from GenPept.129 : >gb|AAC69671.1| (AF019746) lipid A-core:surface polymer ligase WaaL [Escherichia coli]; Lipid A-core, surface polymer ligase 4231245 waaL 1038237 waaL Escherichia coli CFT073 Lipid A-core, surface polymer ligase NP_756310.1 4229992 R 199310 CDS NP_756311.1 26250271 1038238 complement(4231291..4232274) 1 NC_004431.1 Residues 1 to 327 of 327 are 96.63 pct identical to residues 1 to 327 of 327 from GenPept.129 : >gb|AAC69672.1| (AF019746) beta1,3-glucosyltransferase WaaV [Escherichia coli]; beta1,3-glucosyltransferase 4232274 waaV 1038238 waaV Escherichia coli CFT073 beta1,3-glucosyltransferase NP_756311.1 4231291 R 199310 CDS NP_756312.1 26250272 1038245 complement(4232356..4233384) 1 NC_004431.1 Residues 1 to 341 of 342 are 98.24 pct identical to residues 1 to 341 of 341 from GenPept.129 : >gb|AAC69673.1| (AF019746) UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW [Escherichia coli]; UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase 4233384 waaW 1038245 waaW Escherichia coli CFT073 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase NP_756312.1 4232356 R 199310 CDS NP_756313.1 26250273 1038241 complement(4233410..4234102) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3625; Escherichia coli O157:H7 ortholog: z5052; lipopolysaccharide core biosynthesis protein 4234102 rfaY 1038241 rfaY Escherichia coli CFT073 lipopolysaccharide core biosynthesis protein NP_756313.1 4233410 R 199310 CDS NP_756314.1 26250274 1038224 complement(4234112..4235107) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3626; Escherichia coli O157:H7 ortholog: z5051; lipopolysaccharide 1,2-glucosyltransferase 4235107 rfaJ 1038224 rfaJ Escherichia coli CFT073 lipopolysaccharide 1,2-glucosyltransferase NP_756314.1 4234112 R 199310 CDS NP_756315.1 26250275 1038256 complement(4235124..4236140) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3627; Escherichia coli O157:H7 ortholog: z5053; lipopolysaccharide 1,3-galactosyltransferase 4236140 rfaI 1038256 rfaI Escherichia coli CFT073 lipopolysaccharide 1,3-galactosyltransferase NP_756315.1 4235124 R 199310 CDS NP_756316.1 26250276 1038179 complement(4236156..4236962) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3630; Escherichia coli O157:H7 ortholog: z5054; lipopolysaccharide core biosynthesis protein rfaP 4236962 rfaP 1038179 rfaP Escherichia coli CFT073 lipopolysaccharide core biosynthesis protein rfaP NP_756316.1 4236156 R 199310 CDS NP_756317.1 26250277 1038213 complement(4236946..4238070) 1 NC_004431.1 Glucosyltransferase I; Escherichia coli K-12 ortholog: b3631; Escherichia coli O157:H7 ortholog: z5055; lipopolysaccharide core biosynthesis protein rfaG 4238070 rfaG 1038213 rfaG Escherichia coli CFT073 lipopolysaccharide core biosynthesis protein rfaG NP_756317.1 4236946 R 199310 CDS NP_756318.1 26250278 1038250 complement(4238067..4239125) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3632; Escherichia coli O157:H7 ortholog: z5056; lipopolysaccharide core biosynthesis protein 4239125 rfaQ 1038250 rfaQ Escherichia coli CFT073 lipopolysaccharide core biosynthesis protein NP_756318.1 4238067 R 199310 CDS NP_756319.1 26250279 1038246 4239538..4240815 1 NC_004431.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4240815 kdtA 1038246 kdtA Escherichia coli CFT073 3-deoxy-D-manno-octulosonic-acid transferase NP_756319.1 4239538 D 199310 CDS NP_756320.1 26250280 1038251 4240823..4241302 1 NC_004431.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4241302 coaD 1038251 coaD Escherichia coli CFT073 phosphopantetheine adenylyltransferase NP_756320.1 4240823 D 199310 CDS NP_756321.1 26250281 1038243 complement(4241341..4242150) 1 NC_004431.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4242150 mutM 1038243 mutM Escherichia coli CFT073 formamidopyrimidine-DNA glycosylase NP_756321.1 4241341 R 199310 CDS NP_756322.1 26250282 1038249 complement(4242248..4242415) 1 NC_004431.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4242415 rpmG 1038249 rpmG Escherichia coli CFT073 50S ribosomal protein L33 NP_756322.1 4242248 R 199310 CDS NP_756323.1 26250283 1038253 complement(4242436..4242672) 1 NC_004431.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4242672 rpmB 1038253 rpmB Escherichia coli CFT073 50S ribosomal protein L28 NP_756323.1 4242436 R 199310 CDS NP_756324.1 26250284 1038232 complement(4242889..4243563) 1 NC_004431.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4243563 radC 1038232 radC Escherichia coli CFT073 DNA repair protein RadC NP_756324.1 4242889 R 199310 CDS NP_756325.2 161486070 1038234 4243729..4244949 1 NC_004431.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4244949 dfp 1038234 dfp Escherichia coli CFT073 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase NP_756325.2 4243729 D 199310 CDS NP_756326.1 26250286 1038261 4244927..4245385 1 NC_004431.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4245385 dut 1038261 dut Escherichia coli CFT073 deoxyuridine 5'-triphosphate nucleotidohydrolase NP_756326.1 4244927 D 199310 CDS NP_756327.2 161486069 1038257 4245492..4246088 1 NC_004431.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4246088 slmA 1038257 slmA Escherichia coli CFT073 nucleoid occlusion protein NP_756327.2 4245492 D 199310 CDS NP_756328.2 161486068 1038255 complement(4246125..4246766) 1 NC_004431.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4246766 pyrE 1038255 pyrE Escherichia coli CFT073 orotate phosphoribosyltransferase NP_756328.2 4246125 R 199310 CDS NP_756329.2 161486067 1038263 complement(4246832..4247548) 1 NC_004431.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4247548 rph 1038263 rph Escherichia coli CFT073 ribonuclease PH NP_756329.2 4246832 R 199310 CDS NP_756330.1 26250290 1038260 4247675..4248538 1 NC_004431.1 Escherichia coli K-12 ortholog: b3644; Escherichia coli O157:H7 ortholog: z5069; hypothetical protein 4248538 yicC 1038260 yicC Escherichia coli CFT073 hypothetical protein NP_756330.1 4247675 D 199310 CDS NP_756331.2 161486066 1038284 4248760..4249584 1 NC_004431.1 Escherichia coli K-12 ortholog: b3645; Escherichia coli O157:H7 ortholog: z5070; DNA-damage-inducible protein D 4249584 dinD 1038284 dinD Escherichia coli CFT073 DNA-damage-inducible protein D NP_756331.2 4248760 D 199310 CDS NP_756332.1 26250292 1038270 4249822..4250493 1 NC_004431.1 Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071; hypothetical protein 4250493 yicG 1038270 yicG Escherichia coli CFT073 hypothetical protein NP_756332.1 4249822 D 199310 CDS NP_756333.1 26250293 1038244 complement(4250490..4252178) 1 NC_004431.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4252178 ligB 1038244 ligB Escherichia coli CFT073 NAD-dependent DNA ligase LigB NP_756333.1 4250490 R 199310 CDS NP_756334.1 26250294 1038268 complement(4252033..4252296) 1 NC_004431.1 hypothetical protein 4252296 1038268 c4472 Escherichia coli CFT073 hypothetical protein NP_756334.1 4252033 R 199310 CDS NP_756335.2 161486065 1038453 4252430..4253053 1 NC_004431.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4253053 gmk 1038453 gmk Escherichia coli CFT073 guanylate kinase NP_756335.2 4252430 D 199310 CDS NP_756336.1 26250296 1038274 4253108..4253383 1 NC_004431.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4253383 rpoZ 1038274 rpoZ Escherichia coli CFT073 DNA-directed RNA polymerase subunit omega NP_756336.1 4253108 D 199310 CDS NP_756337.1 26250297 1038278 4253402..4255510 1 NC_004431.1 Escherichia coli K-12 ortholog: b3650; Escherichia coli O157:H7 ortholog: z5076; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4255510 spoT 1038278 spoT Escherichia coli CFT073 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase NP_756337.1 4253402 D 199310 CDS NP_756338.1 26250298 1038271 4255517..4256206 1 NC_004431.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4256206 spoU 1038271 spoU Escherichia coli CFT073 tRNA guanosine-2'-O-methyltransferase NP_756338.1 4255517 D 199310 CDS NP_756339.2 161486064 1038359 4256212..4258293 1 NC_004431.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4258293 recG 1038359 recG Escherichia coli CFT073 ATP-dependent DNA helicase RecG NP_756339.2 4256212 D 199310 CDS NP_756340.1 26250300 1038264 complement(4258327..4259532) 1 NC_004431.1 Glutamate permease; Escherichia coli K-12 ortholog: b3653; Escherichia coli O157:H7 ortholog: z5081; Sodium/glutamate symport carrier protein 4259532 gltS 1038264 gltS Escherichia coli CFT073 Sodium/glutamate symport carrier protein NP_756340.1 4258327 R 199310 CDS NP_756341.1 26250301 1038310 4259803..4261203 1 NC_004431.1 Escherichia coli K-12 ortholog: b3654; Escherichia coli O157:H7 ortholog: z5082; purine permease yicE 4261203 yicE 1038310 yicE Escherichia coli CFT073 purine permease yicE NP_756341.1 4259803 D 199310 CDS NP_756342.1 26250302 1038512 4261300..4263033 1 NC_004431.1 Escherichia coli K-12 ortholog: b3655; Escherichia coli O157:H7 ortholog: z5083; hypothetical protein 4263033 yicH 1038512 yicH Escherichia coli CFT073 hypothetical protein NP_756342.1 4261300 D 199310 CDS NP_756343.1 26250303 1038517 complement(4263077..4263796) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5688; hypothetical protein 4263796 1038517 c4481 Escherichia coli CFT073 hypothetical protein NP_756343.1 4263077 R 199310 CDS NP_756344.1 26250304 1038368 complement(4263738..4264703) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0394; Escherichia coli O157:H7 ortholog: z0493; hypothetical protein 4264703 1038368 c4482 Escherichia coli CFT073 hypothetical protein NP_756344.1 4263738 R 199310 CDS NP_756345.1 26250305 1038321 complement(4264718..4265578) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5687; hypothetical protein 4265578 1038321 c4483 Escherichia coli CFT073 hypothetical protein NP_756345.1 4264718 R 199310 CDS NP_756346.1 26250306 1038302 complement(4265659..4266510) 1 NC_004431.1 Residues 1 to 283 of 283 are 39.78 pct identical to residues 1 to 283 of 284 from GenPept.129 : >emb|CAD00212.1| (AL591982) similar to fructose-1,6-biphosphate aldolase type II [Listeria monocytogenes]; aldolase 4266510 1038302 c4484 Escherichia coli CFT073 aldolase NP_756346.1 4265659 R 199310 CDS NP_756347.1 26250307 1038496 complement(4266522..4267613) 1 NC_004431.1 Residues 11 to 358 of 363 are 53.10 pct identical to residues 5 to 355 of 363 from GenPept.129 : >emb|CAC97469.1| (AL596171) similar to PTS system, fructose-specific enzyme IIC component [Listeria innocua]; PTS enzyme-II fructose 4267613 1038496 c4485 Escherichia coli CFT073 PTS enzyme-II fructose NP_756347.1 4266522 R 199310 CDS NP_756348.1 26250308 1038289 complement(4267638..4267952) 1 NC_004431.1 Phosphotransferase enzyme II, B component; Escherichia coli K-12 ortholog: b3950; Escherichia coli O157:H7 ortholog: z5506; PTS system, fructose-like-2 IIB component 1 4267952 1038289 c4486 Escherichia coli CFT073 PTS system, fructose-like-2 IIB component 1 NP_756348.1 4267638 R 199310 CDS NP_756349.1 26250309 1038406 complement(4267970..4268440) 1 NC_004431.1 Residues 1 to 149 of 156 are 48.32 pct identical to residues 6 to 154 of 157 from GenPept.129 : >emb|CAC97471.1| (AL596171) similar to PTS system, fructose-specific enzyme IIA component [Listeria innocua]; phosphotransferase system (PTS), fructose-specific 4268440 1038406 c4487 Escherichia coli CFT073 phosphotransferase system (PTS), fructose-specific NP_756349.1 4267970 R 199310 CDS NP_756350.1 26250310 1038572 complement(4268467..4270065) 1 NC_004431.1 Residues 18 to 515 of 532 are 28.32 pct identical to residues 2 to 483 of 485 from GenPept.129 : >emb|CAD00216.1| (AL591982) similar to transcription regulator [Listeria monocytogenes]; transcriptional antiterminator 4270065 1038572 c4488 Escherichia coli CFT073 transcriptional antiterminator NP_756350.1 4268467 R 199310 CDS NP_756351.1 26250311 1038574 complement(4270305..4272623) 1 NC_004431.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI 4272623 yicI 1038574 yicI Escherichia coli CFT073 alpha-xylosidase YicI NP_756351.1 4270305 R 199310 CDS NP_756352.2 161486063 1038482 complement(4272633..4274015) 1 NC_004431.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4274015 yicJ 1038482 yicJ Escherichia coli CFT073 transporter NP_756352.2 4272633 R 199310 CDS NP_756353.1 26250313 1038554 4274702..4275886 1 NC_004431.1 Escherichia coli K-12 ortholog: b2349; Escherichia coli O157:H7 ortholog: z5087; prophage integrase 4275886 intC 1038554 intC Escherichia coli CFT073 prophage integrase NP_756353.1 4274702 D 199310 CDS NP_756354.1 26250314 1038476 4276297..4277340 1 NC_004431.1 Residues 1 to 347 of 347 are 96.82 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri]; ShiA-like protein 4277340 1038476 c4492 Escherichia coli CFT073 ShiA-like protein NP_756354.1 4276297 D 199310 CDS NP_756355.1 26250315 1038422 4277483..4277713 1 NC_004431.1 hypothetical protein 4277713 1038422 c4493 Escherichia coli CFT073 hypothetical protein NP_756355.1 4277483 D 199310 CDS NP_756356.1 26250316 1038682 complement(4277738..4278832) 1 NC_004431.1 Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis]; transcriptional regulator 4278832 1038682 c4494 Escherichia coli CFT073 transcriptional regulator NP_756356.1 4277738 R 199310 CDS NP_756357.1 26250317 1038562 4279013..4280371 1 NC_004431.1 Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter 4280371 1038562 c4495 Escherichia coli CFT073 hexuronate transporter NP_756357.1 4279013 D 199310 CDS NP_756358.1 26250318 1038555 4280380..4281033 1 NC_004431.1 Residues 3 to 213 of 217 are 62.08 pct identical to residues 2 to 212 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) glucosidase [Yersinia pestis]; glucosidase 4281033 1038555 c4496 Escherichia coli CFT073 glucosidase NP_756358.1 4280380 D 199310 CDS NP_756359.1 26250319 1038509 4280984..4282768 1 NC_004431.1 Residues 13 to 581 of 594 are 74.86 pct identical to residues 213 to 781 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) glucosidase [Yersinia pestis]; glucosidase 4282768 1038509 c4497 Escherichia coli CFT073 glucosidase NP_756359.1 4280984 D 199310 CDS NP_756360.1 26250320 1038666 complement(4283544..4283861) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1632; IS1 protein InsB 4283861 1038666 c4498 Escherichia coli CFT073 IS1 protein InsB NP_756360.1 4283544 R 199310 CDS NP_756361.1 26250321 1038567 complement(4283872..4284084) 1 NC_004431.1 Residues 1 to 69 of 70 are 98.55 pct identical to residues 1 to 69 of 70 from GenPept.129 : >gb|AAK18551.1|AF348706_240 (AF348706) iso-IS1 orf [Shigella flexneri]; hypothetical protein 4284084 1038567 c4499 Escherichia coli CFT073 hypothetical protein NP_756361.1 4283872 R 199310 CDS NP_756362.1 26250322 1038489 complement(4284198..4285697) 1 NC_004431.1 Residues 20 to 492 of 499 are 47.78 pct identical to residues 12 to 476 of 483 from GenPept.129 : >gb|AAF73583.1| (AE002332) amino acid permease [Chlamydia muridarum]; amino acid antiporter 4285697 1038489 c4500 Escherichia coli CFT073 amino acid antiporter NP_756362.1 4284198 R 199310 CDS NP_756363.1 26250323 1038739 complement(4285772..4288141) 1 NC_004431.1 Residues 7 to 750 of 789 are 38.82 pct identical to residues 4 to 744 of 756 from MG1655 : b4117; hypothetical protein 4288141 1038739 c4501 Escherichia coli CFT073 hypothetical protein NP_756363.1 4285772 R 199310 CDS NP_756364.1 26250324 1038757 complement(4288246..4289715) 1 NC_004431.1 Residues 5 to 481 of 489 are 50.10 pct identical to residues 2 to 479 of 485 from GenPept.129 : >gb|AAD19168.1| (AE001683) Arginine/Ornithine Antiporter [Chlamydophila pneumoniae CWL029]; antiporter 4289715 1038757 c4502 Escherichia coli CFT073 antiporter NP_756364.1 4288246 R 199310 CDS NP_756365.1 26250325 1038568 4289968..4290240 1 NC_004431.1 IS1a/IS1b/IS1c/IS1d; Escherichia coli K-12 ortholog: b3444; insertion element IS1 1/2/3/5/6 protein insA 4290240 1038568 c4503 Escherichia coli CFT073 insertion element IS1 1/2/3/5/6 protein insA NP_756365.1 4289968 D 199310 CDS NP_756366.1 26250326 1038809 4290267..4290626 1 NC_004431.1 Escherichia coli K-12 ortholog: b3445; Escherichia coli O157:H7 ortholog: z1562; insertion element IS1 1/5/6 protein insB 4290626 insB 1038809 insB Escherichia coli CFT073 insertion element IS1 1/5/6 protein insB NP_756366.1 4290267 D 199310 CDS NP_756367.1 26250327 1038694 4291249..4291626 1 NC_004431.1 Residues 13 to 125 of 125 are 62.83 pct identical to residues 2 to 114 of 324 from GenPept.129 : >gb|AAL22245.1| (AE008855) oxidoreductase [Salmonella typhimurium LT2]; hypothetical protein 4291626 1038694 c4505 Escherichia coli CFT073 hypothetical protein NP_756367.1 4291249 D 199310 CDS NP_756368.1 26250328 1038625 complement(4291966..4293117) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4284; Escherichia coli O157:H7 ortholog: z2993; transposase insI 4293117 insI 1038625 insI Escherichia coli CFT073 transposase insI NP_756368.1 4291966 R 199310 CDS NP_756369.1 26250329 1038813 4293266..4294078 1 NC_004431.1 Escherichia coli K-12 ortholog: b2089; transposase insF 4294078 1038813 c4507 Escherichia coli CFT073 transposase insF NP_756369.1 4293266 D 199310 CDS NP_756370.1 26250330 1038908 4294099..4294284 1 NC_004431.1 Residues 1 to 61 of 61 are 98.36 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 4294284 1038908 c4508 Escherichia coli CFT073 hypothetical protein NP_756370.1 4294099 D 199310 CDS NP_756371.1 26250331 1038856 4294419..4295747 1 NC_004431.1 Residues 379 to 441 of 442 are 49.20 pct identical to residues 20 to 80 of 90 from GenPept.129 : >gb|AAK99647.1| (AE008459) Hypothetical protein [Streptococcus pneumoniae R6]; hypothetical protein 4295747 1038856 c4509 Escherichia coli CFT073 hypothetical protein NP_756371.1 4294419 D 199310 CDS NP_756372.1 26250332 1038662 4295755..4296330 1 NC_004431.1 hypothetical protein 4296330 1038662 c4510 Escherichia coli CFT073 hypothetical protein NP_756372.1 4295755 D 199310 CDS NP_756373.1 26250333 1038723 complement(4296883..4297608) 1 NC_004431.1 Residues 3 to 238 of 241 are 48.73 pct identical to residues 2 to 239 of 256 from GenPept.129 : >gb|AAL45712.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 4297608 1038723 c4511 Escherichia coli CFT073 hypothetical protein NP_756373.1 4296883 R 199310 CDS NP_756374.1 26250334 1039045 complement(4297605..4298924) 1 NC_004431.1 Residues 30 to 392 of 439 are 40.10 pct identical to residues 20 to 375 of 423 from GenPept.129 : >gb|AAF12682.1|AE001827_20 (AE001827) hypothetical protein [Deinococcus radiodurans]; hypothetical protein 4298924 1039045 c4512 Escherichia coli CFT073 hypothetical protein NP_756374.1 4297605 R 199310 CDS NP_756375.1 26250335 1039072 complement(4298906..4299658) 1 NC_004431.1 Residues 1 to 190 of 250 are 29.41 pct identical to residues 1 to 236 of 298 from GenPept.129 : >gb|AAL45714.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 4299658 1039072 c4513 Escherichia coli CFT073 hypothetical protein NP_756375.1 4298906 R 199310 CDS NP_756376.1 26250336 1039077 complement(4299658..4301442) 1 NC_004431.1 Residues 1 to 594 of 594 are 33.00 pct identical to residues 1 to 606 of 632 from GenPept.129 : >gb|AAL45715.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 4301442 1039077 c4514 Escherichia coli CFT073 hypothetical protein NP_756376.1 4299658 R 199310 CDS NP_756377.1 26250337 1038792 complement(4303106..4303504) 1 NC_004431.1 Residues 1 to 120 of 132 are 39.34 pct identical to residues 324 to 445 of 455 from GenPept.129 : >emb|CAC90312.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein 4303504 1038792 c4517 Escherichia coli CFT073 hypothetical protein NP_756377.1 4303106 R 199310 CDS NP_756378.1 26250338 1038896 complement(4303576..4304013) 1 NC_004431.1 Residues 30 to 145 of 145 are 97.41 pct identical to residues 1 to 116 of 348 from GenPept.129 : >gb|AAG55755.1|AE005312_1 (AE005312) Z1640 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 4304013 1038896 c4518 Escherichia coli CFT073 hypothetical protein NP_756378.1 4303576 R 199310 CDS NP_756379.1 26250339 1038879 complement(4304030..4304158) 1 NC_004431.1 hypothetical protein 4304158 1038879 c4519 Escherichia coli CFT073 hypothetical protein NP_756379.1 4304030 R 199310 CDS NP_756380.1 26250340 1039116 4304606..4304797 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1637; hypothetical protein 4304797 1039116 c4520 Escherichia coli CFT073 hypothetical protein NP_756380.1 4304606 D 199310 CDS NP_756381.1 26250341 1039122 complement(4304850..4305158) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1636; hypothetical protein 4305158 1039122 c4521 Escherichia coli CFT073 hypothetical protein NP_756381.1 4304850 R 199310 CDS NP_756382.1 26250342 1039102 4305133..4305537 1 NC_004431.1 hypothetical protein 4305537 1039102 c4522 Escherichia coli CFT073 hypothetical protein NP_756382.1 4305133 D 199310 CDS NP_756383.1 26250343 1039125 complement(4305179..4305580) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1635; hypothetical protein 4305580 1039125 c4523 Escherichia coli CFT073 hypothetical protein NP_756383.1 4305179 R 199310 CDS NP_756384.1 26250344 1039127 4306029..4307147 1 NC_004431.1 Residues 10 to 370 of 372 are 44.41 pct identical to residues 9 to 375 of 376 from GenPept.129 : >dbj|BAB80598.1| (AP003188) NADPH-dependent butanol dehydrogenase [Clostridium perfringens]; propanol dehydrogenase 4307147 1039127 c4524 Escherichia coli CFT073 propanol dehydrogenase NP_756384.1 4306029 D 199310 CDS NP_756385.1 26250345 1039082 4307287..4307973 1 NC_004431.1 Residues 37 to 218 of 228 are 54.64 pct identical to residues 23 to 205 of 210 from GenPept.129 : >gb|AAD35462.1|AE001717_8 (AE001717) hypothetical protein [Thermotoga maritima]; chormophorylate of CpcA 4307973 1039082 c4525 Escherichia coli CFT073 chormophorylate of CpcA NP_756385.1 4307287 D 199310 CDS NP_756386.1 26250346 1039373 4308028..4308786 1 NC_004431.1 Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710; ethanolamine utilization protein EutJ 4308786 1039373 c4526 Escherichia coli CFT073 ethanolamine utilization protein EutJ NP_756386.1 4308028 D 199310 CDS NP_756387.1 26250347 1039069 4308770..4309495 1 NC_004431.1 hypothetical protein 4309495 1039069 c4527 Escherichia coli CFT073 hypothetical protein NP_756387.1 4308770 D 199310 CDS NP_756388.1 26250348 1039076 4309507..4309776 1 NC_004431.1 Escherichia coli K-12 ortholog: b2456; Escherichia coli O157:H7 ortholog: z3712; ethanolamine utilization protein EutN 4309776 1039076 c4528 Escherichia coli CFT073 ethanolamine utilization protein EutN NP_756388.1 4309507 D 199310 CDS NP_756389.1 26250349 1039428 4309804..4310301 1 NC_004431.1 Residues 25 to 156 of 165 are 50.00 pct identical to residues 199 to 332 of 336 from GenPept.129 : >gb|AAL20954.1| (AE008790) Propanediol utilization: B12 related [Salmonella typhimurium LT2]; hypothetical protein 4310301 1039428 c4529 Escherichia coli CFT073 hypothetical protein NP_756389.1 4309804 D 199310 CDS NP_756390.1 26250350 1039144 4310306..4311526 1 NC_004431.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 4311526 tdcD 1039144 tdcD Escherichia coli CFT073 propionate/acetate kinase NP_756390.1 4310306 D 199310 CDS NP_756391.1 26250351 1039224 complement(4310426..4310605) 1 NC_004431.1 hypothetical protein 4310605 1039224 c4531 Escherichia coli CFT073 hypothetical protein NP_756391.1 4310426 R 199310 CDS NP_756392.1 26250352 1039250 4311760..4312011 1 NC_004431.1 Residues 18 to 67 of 83 are 89.99 pct identical to residues 1 to 50 of 94 from GenPept.129 : >gb|AAL20942.1| (AE008790) Propanediol utilization: polyhedral bodies [Salmonella typhimurium LT2]; hypothetical protein 4312011 1039250 c4532 Escherichia coli CFT073 hypothetical protein NP_756392.1 4311760 D 199310 CDS NP_756393.1 26250353 1039148 4312116..4312901 1 NC_004431.1 Residues 33 to 261 of 261 are 63.31 pct identical to residues 6 to 233 of 233 from SwissProt.40 : >sp|P37449|PDUB_SALTY PROPANEDIOL UTILIZATION PROTEIN PDUB; pduB protein 4312901 1039148 c4533 Escherichia coli CFT073 pduB protein NP_756393.1 4312116 D 199310 CDS NP_756394.1 26250354 1039466 4312962..4314479 1 NC_004431.1 Escherichia coli K-12 ortholog: b2455; Escherichia coli O157:H7 ortholog: z3711; ethanolamine utilization protein EutE 4314479 1039466 c4534 Escherichia coli CFT073 ethanolamine utilization protein EutE NP_756394.1 4312962 D 199310 CDS NP_756395.1 26250355 1039132 4314503..4314802 1 NC_004431.1 hypothetical protein 4314802 1039132 c4535 Escherichia coli CFT073 hypothetical protein NP_756395.1 4314503 D 199310 CDS NP_756396.1 26250356 1039097 4314777..4315388 1 NC_004431.1 Residues 14 to 198 of 203 are 56.75 pct identical to residues 3 to 187 of 188 from GenPept.129 : >gb|AAL45236.1| (AE009373) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 4315388 1039097 c4536 Escherichia coli CFT073 hypothetical protein NP_756396.1 4314777 D 199310 CDS NP_756397.1 26250357 1039560 4315437..4317989 1 NC_004431.1 Residues 10 to 849 of 850 are 34.39 pct identical to residues 2 to 765 of 765 from MG1655 : b3951; hypothetical protein 4317989 1039560 c4537 Escherichia coli CFT073 hypothetical protein NP_756397.1 4315437 D 199310 CDS NP_756398.1 26250358 1039446 4318098..4319015 1 NC_004431.1 Escherichia coli K-12 ortholog: b0824; Escherichia coli O157:H7 ortholog: z1047; pyruvate formate-lyase 3 activating enzyme 4319015 1039446 c4538 Escherichia coli CFT073 pyruvate formate-lyase 3 activating enzyme NP_756398.1 4318098 D 199310 CDS NP_756399.1 26250359 1039531 4319152..4320057 1 NC_004431.1 Residues 6 to 294 of 301 are 32.72 pct identical to residues 23 to 340 of 349 from GenPept.129 : >gb|AAG20144.1| (AE005092) Vng1965h [Halobacterium sp. NRC-1]; hypothetical protein 4320057 1039531 c4539 Escherichia coli CFT073 hypothetical protein NP_756399.1 4319152 D 199310 CDS NP_756400.1 26250360 1039533 4320543..4321082 1 NC_004431.1 Residues 47 to 179 of 179 are 43.82 pct identical to residues 2 to 163 of 418 from GenPept.129 : >dbj|BAB04330.1| (AP001509) transposase (11) [Bacillus halodurans]; maturase-related protein 4321082 1039533 c4540 Escherichia coli CFT073 maturase-related protein NP_756400.1 4320543 D 199310 CDS NP_756401.1 26250361 1039477 4321110..4321631 1 NC_004431.1 Residues 1 to 173 of 173 are 50.85 pct identical to residues 228 to 402 of 490 from GenPept.129 : >gb|AAB68949.1| (U77945) maturase-related protein [Pseudomonas alcaligenes]; maturase-related protein 4321631 1039477 c4541 Escherichia coli CFT073 maturase-related protein NP_756401.1 4321110 D 199310 CDS NP_756402.1 26250362 1039559 4321370..4321690 1 NC_004431.1 hypothetical protein 4321690 1039559 c4542 Escherichia coli CFT073 hypothetical protein NP_756402.1 4321370 D 199310 CDS NP_756403.1 26250363 1039595 4321940..4322074 1 NC_004431.1 hypothetical protein 4322074 1039595 c4543 Escherichia coli CFT073 hypothetical protein NP_756403.1 4321940 D 199310 CDS NP_756404.1 26250364 1039584 4321953..4322141 1 NC_004431.1 hypothetical protein 4322141 1039584 c4544 Escherichia coli CFT073 hypothetical protein NP_756404.1 4321953 D 199310 CDS NP_756405.1 26250365 1039627 4322181..4323443 1 NC_004431.1 Residues 12 to 416 of 420 are 34.38 pct identical to residues 1 to 407 of 410 from GenPept.129 : >dbj|BAB80633.1| (AP003188) two-component sensor histidine kinase [Clostridium perfringens]; hypothetical protein 4323443 1039627 c4545 Escherichia coli CFT073 hypothetical protein NP_756405.1 4322181 D 199310 CDS NP_756406.1 26250366 1039575 4323460..4324515 1 NC_004431.1 Residues 245 to 342 of 351 are 45.91 pct identical to residues 178 to 275 of 317 from GenPept.129 : >emb|CAD01088.1| (AJ297723) transcriptional regulator [Lactobacillus collinoides]; hypothetical protein 4324515 1039575 c4546 Escherichia coli CFT073 hypothetical protein NP_756406.1 4323460 D 199310 CDS NP_756407.1 26250367 1039628 4324644..4325795 1 NC_004431.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 4325795 1039628 c4547 Escherichia coli CFT073 S-adenosylmethionine synthetase NP_756407.1 4324644 D 199310 CDS NP_756408.1 26250368 1039624 4325744..4326385 1 NC_004431.1 Residues 37 to 121 of 213 are 55.29 pct identical to residues 6 to 89 of 94 from GenPept.129 : >gb|AAL94296.1| (AE010523) Ethanolamine utilization protein eutM precursor [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 4326385 1039624 c4548 Escherichia coli CFT073 hypothetical protein NP_756408.1 4325744 D 199310 CDS NP_756409.1 26250369 1039626 complement(4326878..4327087) 1 NC_004431.1 Residues 11 to 60 of 69 are 47.99 pct identical to residues 7 to 56 of 107 from GenPept.129 : >gb|AAL23089.1| (AE008900) transcriptional activator of superoxide response regulon (AraC/XylS family) [Salmonella typhimurium LT2]; hypothetical protein 4327087 1039626 c4549 Escherichia coli CFT073 hypothetical protein NP_756409.1 4326878 R 199310 CDS NP_756410.1 26250370 1039630 complement(4327162..4327731) 1 NC_004431.1 Residues 9 to 178 of 189 are 29.31 pct identical to residues 1 to 174 of 212 from GenPept.129 : >gb|AAG06962.1|AE004778_6 (AE004778) probable transcriptional regulator [Pseudomonas aeruginosa]; hypothetical protein 4327731 1039630 c4550 Escherichia coli CFT073 hypothetical protein NP_756410.1 4327162 R 199310 CDS NP_756411.1 26250371 1039629 complement(4327831..4328895) 1 NC_004431.1 Residues 33 to 328 of 354 are 21.82 pct identical to residues 185 to 490 of 1046 from GenPept.129 : >gb|AAG03815.1|AE004479_10 (AE004479) RND multidrug efflux transporter MexB [Pseudomonas aeruginosa]; hypothetical protein 4328895 1039629 c4551 Escherichia coli CFT073 hypothetical protein NP_756411.1 4327831 R 199310 CDS NP_756412.1 26250372 1039633 4329034..4329369 1 NC_004431.1 Escherichia coli K-12 ortholog: b4272; transposase insC 4329369 1039633 c4552 Escherichia coli CFT073 transposase insC NP_756412.1 4329034 D 199310 CDS YP_004853833.1 347357948 1039656 4329417..4329608 1 NC_004431.1 hypothetical protein 4329608 1039656 c4553 Escherichia coli CFT073 hypothetical protein YP_004853833.1 4329417 D 199310 CDS YP_004853834.1 347357918 1039637 complement(4329427..4329759) 1 NC_004431.1 hypothetical protein 4329759 1039637 c4554 Escherichia coli CFT073 hypothetical protein YP_004853834.1 4329427 R 199310 CDS YP_004853835.1 347357919 1039638 complement(4329522..4329647) 1 NC_004431.1 hypothetical protein 4329647 1039638 c4555 Escherichia coli CFT073 hypothetical protein YP_004853835.1 4329522 R 199310 CDS NP_756416.1 26250376 1039635 complement(4329644..4329877) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1627; hypothetical protein 4329877 1039635 c4556 Escherichia coli CFT073 hypothetical protein NP_756416.1 4329644 R 199310 CDS NP_756417.1 26250377 1039649 complement(4329946..4330710) 1 NC_004431.1 Residues 104 to 248 of 254 are 88.27 pct identical to residues 30 to 174 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli]; hypothetical protein 4330710 1039649 c4557 Escherichia coli CFT073 hypothetical protein NP_756417.1 4329946 R 199310 CDS NP_756418.1 26250378 1039640 complement(4330868..4331599) 1 NC_004431.1 Residues 1 to 243 of 243 are 85.59 pct identical to residues 1 to 243 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4331599 1039640 c4558 Escherichia coli CFT073 hypothetical protein NP_756418.1 4330868 R 199310 CDS NP_756419.1 26250379 1039639 4331010..4331156 1 NC_004431.1 hypothetical protein 4331156 1039639 c4559 Escherichia coli CFT073 hypothetical protein NP_756419.1 4331010 D 199310 CDS NP_756420.1 26250380 1039665 4331703..4331861 1 NC_004431.1 hypothetical protein 4331861 1039665 c4560 Escherichia coli CFT073 hypothetical protein NP_756420.1 4331703 D 199310 CDS NP_756421.1 26250381 1039666 complement(4333119..4334249) 1 NC_004431.1 hypothetical protein 4334249 1039666 c4561 Escherichia coli CFT073 hypothetical protein NP_756421.1 4333119 R 199310 CDS NP_756424.1 26250384 1039643 4334434..4335318 1 NC_004431.1 Residues 1 to 294 of 294 are 94.55 pct identical to residues 1 to 294 of 294 from GenPept.129 : >gb|AAL67395.1|AF447814_63 (AF447814) unknown [Escherichia coli]; hypothetical protein 4335318 1039643 c4564 Escherichia coli CFT073 hypothetical protein NP_756424.1 4334434 D 199310 CDS NP_756425.1 26250385 1039661 4335337..4335492 1 NC_004431.1 hypothetical protein 4335492 1039661 c4565 Escherichia coli CFT073 hypothetical protein NP_756425.1 4335337 D 199310 CDS NP_756426.1 26250386 1039641 4335521..4336201 1 NC_004431.1 Escherichia coli K-12 ortholog: b2634; transcriptional regulator YfjR 4336201 1039641 c4566 Escherichia coli CFT073 transcriptional regulator YfjR NP_756426.1 4335521 D 199310 CDS NP_756427.1 26250387 1039651 complement(4336085..4336216) 1 NC_004431.1 hypothetical protein 4336216 1039651 c4567 Escherichia coli CFT073 hypothetical protein NP_756427.1 4336085 R 199310 CDS NP_756428.1 26250388 1039645 4336244..4337026 1 NC_004431.1 Residues 1 to 161 of 260 are 99.37 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4337026 1039645 c4568 Escherichia coli CFT073 hypothetical protein NP_756428.1 4336244 D 199310 CDS NP_756429.1 26250389 1039655 4337032..4337265 1 NC_004431.1 Escherichia coli K-12 ortholog: b0249; hypothetical protein 4337265 1039655 c4569 Escherichia coli CFT073 hypothetical protein NP_756429.1 4337032 D 199310 CDS NP_756430.1 26250390 1039657 4337355..4338173 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 4338173 1039657 c4570 Escherichia coli CFT073 hypothetical protein NP_756430.1 4337355 D 199310 CDS NP_756431.1 26250391 1039663 4338265..4338750 1 NC_004431.1 Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 4338750 1039663 c4571 Escherichia coli CFT073 hypothetical protein NP_756431.1 4338265 D 199310 CDS NP_756432.1 26250392 1039662 complement(4338319..4338765) 1 NC_004431.1 Residues 6 to 143 of 148 are 85.50 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 4338765 1039662 c4572 Escherichia coli CFT073 hypothetical protein NP_756432.1 4338319 R 199310 CDS NP_756433.1 26250393 1039660 4338795..4339241 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 4339241 1039660 c4573 Escherichia coli CFT073 radC-like protein yeeS NP_756433.1 4338795 D 199310 CDS NP_756434.1 26250394 1039652 4339304..4339525 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 4339525 1039652 c4574 Escherichia coli CFT073 hypothetical protein NP_756434.1 4339304 D 199310 CDS NP_756435.1 26250395 1039670 4339544..4339969 1 NC_004431.1 Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z1658; hypothetical protein 4339969 1039670 c4575 Escherichia coli CFT073 hypothetical protein NP_756435.1 4339544 D 199310 CDS NP_756436.1 26250396 1039664 4340059..4340436 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 4340436 1039664 c4576 Escherichia coli CFT073 hypothetical protein NP_756436.1 4340059 D 199310 CDS NP_756437.1 26250397 1039671 4340433..4340855 1 NC_004431.1 Residues 79 to 140 of 140 are 98.38 pct identical to residues 4 to 65 of 65 from GenPept.129 : >gb|AAL08480.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 4340855 1039671 c4577 Escherichia coli CFT073 hypothetical protein NP_756437.1 4340433 D 199310 CDS NP_756438.1 26250398 1039668 4340940..4341782 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 4341782 1039668 c4578 Escherichia coli CFT073 hypothetical protein NP_756438.1 4340940 D 199310 CDS NP_756439.1 26250399 1039674 complement(4341555..4341758) 1 NC_004431.1 hypothetical protein 4341758 1039674 c4579 Escherichia coli CFT073 hypothetical protein NP_756439.1 4341555 R 199310 CDS NP_756440.1 26250400 1039673 4342016..4342237 1 NC_004431.1 Residues 3 to 70 of 73 are 41.24 pct identical to residues 148 to 227 of 327 from GenPept.129 : >emb|CAD03240.1| (AL627280) DNA-binding protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 4342237 1039673 c4580 Escherichia coli CFT073 hypothetical protein NP_756440.1 4342016 D 199310 CDS NP_756441.1 26250401 1039672 4342378..4342875 1 NC_004431.1 hypothetical protein 4342875 1039672 c4581 Escherichia coli CFT073 hypothetical protein NP_756441.1 4342378 D 199310 CDS NP_756442.1 26250402 1039677 4342988..4343965 1 NC_004431.1 Escherichia coli K-12 ortholog: b3660; Escherichia coli O157:H7 ortholog: z5146; transport protein YicL 4343965 yicL 1039677 yicL Escherichia coli CFT073 transport protein YicL NP_756442.1 4342988 D 199310 CDS NP_756443.1 26250403 1039756 complement(4343969..4344787) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3661; Escherichia coli O157:H7 ortholog: z5147; cytoplasmic membrane lipoprotein-28 4344787 nlpA 1039756 nlpA Escherichia coli CFT073 cytoplasmic membrane lipoprotein-28 NP_756443.1 4343969 R 199310 CDS NP_756444.1 26250404 1039688 complement(4344784..4344927) 1 NC_004431.1 hypothetical protein 4344927 1039688 c4584 Escherichia coli CFT073 hypothetical protein NP_756444.1 4344784 R 199310 CDS NP_756445.1 26250405 1039701 4344940..4345302 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5148; hypothetical protein 4345302 1039701 c4585 Escherichia coli CFT073 hypothetical protein NP_756445.1 4344940 D 199310 CDS NP_756446.2 161486062 1039828 complement(4345343..4346533) 1 NC_004431.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4346533 nepI 1039828 nepI Escherichia coli CFT073 ribonucleoside transporter NP_756446.2 4345343 R 199310 CDS NP_756447.1 26250407 1039708 complement(4346744..4347223) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3663; Escherichia coli O157:H7 ortholog: z5152; hypothetical protein 4347223 yicN 1039708 yicN Escherichia coli CFT073 hypothetical protein NP_756447.1 4346744 R 199310 CDS NP_756448.1 26250408 1039800 complement(4347249..4348661) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3664; Escherichia coli O157:H7 ortholog: z5209; hypothetical protein 4348661 yicO 1039800 yicO Escherichia coli CFT073 hypothetical protein NP_756448.1 4347249 R 199310 CDS NP_756449.1 26250409 1039826 4348758..4350524 1 NC_004431.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4350524 yicP 1039826 yicP Escherichia coli CFT073 cryptic adenine deaminase NP_756449.1 4348758 D 199310 CDS NP_756450.1 26250410 1039821 complement(4350571..4351962) 1 NC_004431.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4351962 uhpT 1039821 uhpT Escherichia coli CFT073 sugar phosphate antiporter NP_756450.1 4350571 R 199310 CDS NP_756451.1 26250411 1039717 complement(4352100..4353422) 1 NC_004431.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4353422 uhpC 1039717 uhpC Escherichia coli CFT073 regulatory protein UhpC NP_756451.1 4352100 R 199310 CDS NP_756452.1 26250412 1039825 complement(4353429..4354937) 1 NC_004431.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4354937 uhpB 1039825 uhpB Escherichia coli CFT073 sensory histidine kinase UhpB NP_756452.1 4353429 R 199310 CDS NP_756453.1 26250413 1039847 complement(4354931..4355521) 1 NC_004431.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4355521 uhpA 1039847 uhpA Escherichia coli CFT073 DNA-binding transcriptional activator UhpA NP_756453.1 4354931 R 199310 CDS NP_756454.1 26250414 1039675 4355936..4356796 1 NC_004431.1 hypothetical protein 4356796 1039675 c4594 Escherichia coli CFT073 hypothetical protein NP_756454.1 4355936 D 199310 CDS NP_756455.1 26250415 1039669 complement(4356987..4357277) 1 NC_004431.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4357277 ilvN 1039669 ilvN Escherichia coli CFT073 acetolactate synthase 1 regulatory subunit NP_756455.1 4356987 R 199310 CDS NP_756456.1 26250416 1039852 complement(4357281..4358969) 1 NC_004431.1 catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase catalytic subunit 4358969 ilvB 1039852 ilvB Escherichia coli CFT073 acetolactate synthase catalytic subunit NP_756456.1 4357281 R 199310 CDS NP_756457.1 26250417 1039830 complement(4359075..4359173) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3672; ilvB operon leader peptide 4359173 ivbL 1039830 ivbL Escherichia coli CFT073 ilvB operon leader peptide NP_756457.1 4359075 R 199310 CDS NP_756458.1 26250418 1039829 4359568..4360758 1 NC_004431.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4360758 emrD 1039829 emrD Escherichia coli CFT073 multidrug resistance protein D NP_756458.1 4359568 D 199310 CDS NP_756459.1 26250419 1039840 complement(4360766..4361263) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3674; Escherichia coli O157:H7 ortholog: z5169; hypothetical protein 4361263 yidF 1039840 yidF Escherichia coli CFT073 hypothetical protein NP_756459.1 4360766 R 199310 CDS NP_756460.1 26250420 1039845 complement(4361260..4361622) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3675; Escherichia coli O157:H7 ortholog: z5170; hypothetical protein 4361622 yidG 1039845 yidG Escherichia coli CFT073 hypothetical protein NP_756460.1 4361260 R 199310 CDS NP_756461.1 26250421 1039878 complement(4361612..4362019) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3676; Escherichia coli O157:H7 ortholog: z5171; hypothetical protein 4362019 yidH 1039878 yidH Escherichia coli CFT073 hypothetical protein NP_756461.1 4361612 R 199310 CDS NP_756462.1 26250422 1039861 complement(4362019..4363512) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3678; Escherichia coli O157:H7 ortholog: z5173; sulfatase yidJ 4363512 yidJ 1039861 yidJ Escherichia coli CFT073 sulfatase yidJ NP_756462.1 4362019 R 199310 CDS NP_756463.1 26250423 1039774 complement(4363509..4365224) 1 NC_004431.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK 4365224 yidK 1039774 yidK Escherichia coli CFT073 symporter YidK NP_756463.1 4363509 R 199310 CDS NP_756464.1 26250424 1039859 4365361..4366257 1 NC_004431.1 Escherichia coli K-12 ortholog: b3680; Escherichia coli O157:H7 ortholog: z5175; transcriptional regulator YidL 4366257 yidL 1039859 yidL Escherichia coli CFT073 transcriptional regulator YidL NP_756464.1 4365361 D 199310 CDS NP_756465.2 161486061 1040032 complement(4366347..4368008) 1 NC_004431.1 ORFA; Escherichia coli K-12 ortholog: b3685; Escherichia coli O157:H7 ortholog: z5181; hypothetical protein 4368008 yidE 1040032 yidE Escherichia coli CFT073 hypothetical protein NP_756465.2 4366347 R 199310 CDS NP_756466.1 26250426 1040033 4368038..4368208 1 NC_004431.1 hypothetical protein 4368208 1040033 c4605 Escherichia coli CFT073 hypothetical protein NP_756466.1 4368038 D 199310 CDS NP_756467.2 161486060 1039882 complement(4368205..4368633) 1 NC_004431.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4368633 ibpB 1039882 ibpB Escherichia coli CFT073 heat shock chaperone IbpB NP_756467.2 4368205 R 199310 CDS NP_756468.2 229106366 1039864 complement(4368745..4369158) 1 NC_004431.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4369158 ibpA 1039864 ibpA Escherichia coli CFT073 heat shock protein IbpA NP_756468.2 4368745 R 199310 CDS NP_756469.2 161486059 1039835 4369464..4369796 1 NC_004431.1 Escherichia coli K-12 ortholog: b3688; Escherichia coli O157:H7 ortholog: z5184; hypothetical protein 4369796 yidQ 1039835 yidQ Escherichia coli CFT073 hypothetical protein NP_756469.2 4369464 D 199310 CDS NP_756470.1 26250430 1040021 complement(4369798..4371048) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3689; Escherichia coli O157:H7 ortholog: z5185; hypothetical protein 4371048 yidR 1040021 yidR Escherichia coli CFT073 hypothetical protein NP_756470.1 4369798 R 199310 CDS NP_756471.1 26250431 1039850 4370980..4371108 1 NC_004431.1 hypothetical protein 4371108 1039850 c4610 Escherichia coli CFT073 hypothetical protein NP_756471.1 4370980 D 199310 CDS NP_756472.2 161486058 1039885 4371113..4372213 1 NC_004431.1 FAD/NAD(P)-binding domain; oxidoreductase 4372213 yidS 1039885 yidS Escherichia coli CFT073 oxidoreductase NP_756472.2 4371113 D 199310 CDS NP_756473.1 26250433 1040044 complement(4372174..4373511) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3691; Escherichia coli O157:H7 ortholog: z4105; D-galactonate transporter 4373511 dgoT 1040044 dgoT Escherichia coli CFT073 D-galactonate transporter NP_756473.1 4372174 R 199310 CDS NP_756474.1 26250434 1040027 complement(4375333..4376211) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3693; 2-dehydro-3-deoxygalactonokinase 4376211 dgoK 1040027 dgoK Escherichia coli CFT073 2-dehydro-3-deoxygalactonokinase NP_756474.1 4375333 R 199310 CDS NP_756475.1 26250435 1039896 complement(4376208..4376897) 1 NC_004431.1 Fusion of Escherichia coli K-12 B3694 and B3695; Residues 1 to 229 of 229 are 99.12 pct identical to residues 1 to 229 of 229 from SwissProt.40 : >sp|P31460|DGOR_ECOLI GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR; hypothetical protein 4376897 1039896 c4616 Escherichia coli CFT073 hypothetical protein NP_756475.1 4376208 R 199310 CDS NP_756476.1 26250436 1040038 4377158..4377649 1 NC_004431.1 Residues 27 to 143 of 163 are 61.86 pct identical to residues 2 to 119 of 223 from MG1655 : b3696; hypothetical protein 4377649 1040038 c4617 Escherichia coli CFT073 hypothetical protein NP_756476.1 4377158 D 199310 CDS NP_756477.1 26250437 1039888 4377585..4377782 1 NC_004431.1 Residues 6 to 42 of 65 are 62.16 pct identical to residues 250 to 286 of 325 from GenPept.129 : >gb|AAG58893.1|AE005600_11 (AE005600) replicase [Escherichia coli O157:H7 EDL933]; hypothetical protein 4377782 1039888 c4618 Escherichia coli CFT073 hypothetical protein NP_756477.1 4377585 D 199310 CDS NP_756478.1 26250438 1039934 complement(4377876..4378688) 1 NC_004431.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4378688 yidA 1039934 yidA Escherichia coli CFT073 sugar phosphatase NP_756478.1 4377876 R 199310 CDS NP_756479.1 26250439 1040028 complement(4378803..4379210) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3698; Escherichia coli O157:H7 ortholog: z5189; hypothetical protein 4379210 yidB 1040028 yidB Escherichia coli CFT073 hypothetical protein NP_756479.1 4378803 R 199310 CDS NP_756480.1 26250440 1040039 complement(4379441..4381858) 1 NC_004431.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4381858 gyrB 1040039 gyrB Escherichia coli CFT073 DNA gyrase subunit B NP_756480.1 4379441 R 199310 CDS NP_756481.1 26250441 1040040 complement(4381884..4382957) 1 NC_004431.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4382957 recF 1040040 recF Escherichia coli CFT073 recombination protein F NP_756481.1 4381884 R 199310 CDS NP_756482.1 26250442 1040053 complement(4382957..4384057) 1 NC_004431.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4384057 dnaN 1040053 dnaN Escherichia coli CFT073 DNA polymerase III subunit beta NP_756482.1 4382957 R 199310 CDS NP_756483.1 26250443 1040056 complement(4385760..4385960) 1 NC_004431.1 hypothetical protein 4385960 1040056 c4626 Escherichia coli CFT073 hypothetical protein NP_756483.1 4385760 R 199310 CDS NP_756484.1 26250444 1040142 4386073..4386213 1 NC_004431.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4386213 rpmH 1040142 rpmH Escherichia coli CFT073 50S ribosomal protein L34 NP_756484.1 4386073 D 199310 CDS NP_756485.1 26250445 1040070 4386230..4386589 1 NC_004431.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4386589 rnpA 1040070 rnpA Escherichia coli CFT073 ribonuclease P NP_756485.1 4386230 D 199310 CDS NP_756486.1 26250446 1040071 4386813..4388459 1 NC_004431.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4388459 yidC 1040071 yidC Escherichia coli CFT073 inner membrane protein translocase component YidC NP_756486.1 4386813 D 199310 CDS NP_756487.1 26250447 1040063 4388565..4389929 1 NC_004431.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4389929 trmE 1040063 trmE Escherichia coli CFT073 tRNA modification GTPase TrmE NP_756487.1 4388565 D 199310 CDS NP_756488.1 26250448 1040125 4390171..4390245 1 NC_004431.1 Escherichia coli K-12 ortholog: b3707; tryptophanase leader peptide 4390245 tnaL 1040125 tnaL Escherichia coli CFT073 tryptophanase leader peptide NP_756488.1 4390171 D 199310 CDS NP_756489.1 26250449 1040088 4390451..4391881 1 NC_004431.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4391881 tnaA 1040088 tnaA Escherichia coli CFT073 tryptophanase NP_756489.1 4390451 D 199310 CDS NP_756490.1 26250450 1040072 4391973..4393220 1 NC_004431.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4393220 tnaB 1040072 tnaB Escherichia coli CFT073 tryptophan permease TnaB NP_756490.1 4391973 D 199310 CDS NP_756491.1 26250451 1040098 4393352..4394527 1 NC_004431.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4394527 yidY 1040098 yidY Escherichia coli CFT073 multidrug efflux system protein MdtL NP_756491.1 4393352 D 199310 CDS NP_756492.1 26250452 1040217 4394493..4395461 1 NC_004431.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4395461 yidZ 1040217 yidZ Escherichia coli CFT073 DNA-binding transcriptional regulator YidZ NP_756492.1 4394493 D 199310 CDS NP_756493.1 26250453 1040126 4395606..4396367 1 NC_004431.1 Escherichia coli K-12 ortholog: b3712; Escherichia coli O157:H7 ortholog: z5207; hypothetical protein 4396367 yieE 1040126 yieE Escherichia coli CFT073 hypothetical protein NP_756493.1 4395606 D 199310 CDS NP_756494.1 26250454 1040117 4396389..4396955 1 NC_004431.1 Escherichia coli K-12 ortholog: b3713; Escherichia coli O157:H7 ortholog: z5208; hypothetical protein 4396955 yieF 1040117 yieF Escherichia coli CFT073 hypothetical protein NP_756494.1 4396389 D 199310 CDS NP_756495.1 26250455 1040215 complement(4397009..4398346) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3714; Escherichia coli O157:H7 ortholog: z5209; hypothetical protein 4398346 yieG 1040215 yieG Escherichia coli CFT073 hypothetical protein NP_756495.1 4397009 R 199310 CDS NP_756496.1 26250456 1040089 4398513..4399178 1 NC_004431.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4399178 yieH 1040089 yieH Escherichia coli CFT073 6-phosphogluconate phosphatase NP_756496.1 4398513 D 199310 CDS NP_756497.1 26250457 1040143 4399245..4399718 1 NC_004431.1 might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4399718 yieI 1040143 yieI Escherichia coli CFT073 inner membrane protein NP_756497.1 4399245 D 199310 CDS NP_756498.1 26250458 1040231 complement(4399800..4400522) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3718; 6-phosphogluconolactonase 4400522 yieK 1040231 yieK Escherichia coli CFT073 6-phosphogluconolactonase NP_756498.1 4399800 R 199310 CDS NP_756499.1 26250459 1040228 complement(4400537..4401739) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3719; hypothetical protein 4401739 yieL 1040228 yieL Escherichia coli CFT073 hypothetical protein NP_756499.1 4400537 R 199310 CDS NP_756500.1 26250460 1040219 complement(4401733..4403349) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3720; hypothetical protein 4403349 1040219 c4642 Escherichia coli CFT073 hypothetical protein NP_756500.1 4401733 R 199310 CDS NP_756501.1 26250461 1040186 complement(4403435..4404829) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3721; Escherichia coli O157:H7 ortholog: z4024; 6-phospho-beta-glucosidase 4404829 bglB 1040186 bglB Escherichia coli CFT073 6-phospho-beta-glucosidase NP_756501.1 4403435 R 199310 CDS NP_756502.1 26250462 1040227 complement(4404848..4406797) 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunits IIABC 4406797 bglF 1040227 bglF Escherichia coli CFT073 PTS system beta-glucoside-specific transporter subunits IIABC NP_756502.1 4404848 R 199310 CDS NP_756503.1 26250463 1040190 4405947..4406087 1 NC_004431.1 hypothetical protein 4406087 1040190 c4645 Escherichia coli CFT073 hypothetical protein NP_756503.1 4405947 D 199310 CDS NP_756504.1 26250464 1040214 complement(4406856..4407716) 1 NC_004431.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4407716 bglG 1040214 bglG Escherichia coli CFT073 transcriptional antiterminator BglG NP_756504.1 4406856 R 199310 CDS NP_756505.1 26250465 1040147 4407758..4407880 1 NC_004431.1 hypothetical protein 4407880 1040147 c4647 Escherichia coli CFT073 hypothetical protein NP_756505.1 4407758 D 199310 CDS NP_756506.2 161486057 1040241 complement(4407978..4408703) 1 NC_004431.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4408703 phoU 1040241 phoU Escherichia coli CFT073 transcriptional regulator PhoU NP_756506.2 4407978 R 199310 CDS NP_756507.1 26250467 1040237 complement(4408718..4409491) 1 NC_004431.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4409491 pstB 1040237 pstB Escherichia coli CFT073 phosphate transporter ATP-binding protein NP_756507.1 4408718 R 199310 CDS NP_756508.1 26250468 1040222 4408751..4409545 1 NC_004431.1 hypothetical protein 4409545 1040222 c4650 Escherichia coli CFT073 hypothetical protein NP_756508.1 4408751 D 199310 CDS NP_756509.1 26250469 1040220 complement(4409582..4410472) 1 NC_004431.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4410472 pstA 1040220 pstA Escherichia coli CFT073 phosphate transporter permease subunit PtsA NP_756509.1 4409582 R 199310 CDS NP_756510.1 26250470 1040236 complement(4410472..4411431) 1 NC_004431.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4411431 pstC 1040236 pstC Escherichia coli CFT073 phosphate transporter permease subunit PstC NP_756510.1 4410472 R 199310 CDS NP_756511.1 26250471 1040226 complement(4411518..4412558) 1 NC_004431.1 PBP; Escherichia coli K-12 ortholog: b3728; Escherichia coli O157:H7 ortholog: z5219; phosphate ABC transporter periplasmic substrate-binding protein PstS 4412558 pstS 1040226 pstS Escherichia coli CFT073 phosphate ABC transporter periplasmic substrate-binding protein PstS NP_756511.1 4411518 R 199310 CDS NP_756512.1 26250472 1040221 complement(4412872..4414701) 1 NC_004431.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4414701 glmS 1040221 glmS Escherichia coli CFT073 glucosamine--fructose-6-phosphate aminotransferase NP_756512.1 4412872 R 199310 CDS NP_756513.1 26250473 1040271 complement(4414862..4416232) 1 NC_004431.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4416232 glmU 1040271 glmU Escherichia coli CFT073 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_756513.1 4414862 R 199310 CDS NP_756514.1 26250474 1040238 4416478..4417029 1 NC_004431.1 hypothetical protein 4417029 1040238 c4656 Escherichia coli CFT073 hypothetical protein NP_756514.1 4416478 D 199310 CDS NP_756515.1 26250475 1040232 complement(4416586..4417005) 1 NC_004431.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4417005 atpC 1040232 atpC Escherichia coli CFT073 ATP synthase F0F1 subunit epsilon NP_756515.1 4416586 R 199310 CDS NP_756516.1 26250476 1040230 complement(4417026..4418408) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4418408 atpD 1040230 atpD Escherichia coli CFT073 ATP synthase F0F1 subunit beta NP_756516.1 4417026 R 199310 CDS NP_756517.1 26250477 1040268 complement(4418435..4419298) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4419298 atpG 1040268 atpG Escherichia coli CFT073 ATP synthase F0F1 subunit gamma NP_756517.1 4418435 R 199310 CDS NP_756518.1 26250478 1040243 complement(4419349..4420890) 1 NC_004431.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4420890 atpA 1040243 atpA Escherichia coli CFT073 ATP synthase F0F1 subunit alpha NP_756518.1 4419349 R 199310 CDS NP_756519.1 26250479 1040235 4419358..4421037 1 NC_004431.1 hypothetical protein 4421037 1040235 c4661 Escherichia coli CFT073 hypothetical protein NP_756519.1 4419358 D 199310 CDS NP_756520.1 26250480 1040229 complement(4420903..4421436) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4421436 atpH 1040229 atpH Escherichia coli CFT073 ATP synthase F0F1 subunit delta NP_756520.1 4420903 R 199310 CDS NP_756521.1 26250481 1040296 4421077..4421814 1 NC_004431.1 hypothetical protein 4421814 1040296 c4663 Escherichia coli CFT073 hypothetical protein NP_756521.1 4421077 D 199310 CDS NP_756522.1 26250482 1040262 complement(4421451..4421921) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4421921 atpF 1040262 atpF Escherichia coli CFT073 ATP synthase F0F1 subunit B NP_756522.1 4421451 R 199310 CDS NP_756523.1 26250483 1040254 complement(4421983..4422222) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4422222 atpE 1040254 atpE Escherichia coli CFT073 ATP synthase F0F1 subunit C NP_756523.1 4421983 R 199310 CDS NP_756524.1 26250484 1040240 complement(4422269..4423084) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4423084 atpB 1040240 atpB Escherichia coli CFT073 ATP synthase F0F1 subunit A NP_756524.1 4422269 R 199310 CDS NP_756525.2 161486056 1040294 complement(4423093..4423473) 1 NC_004431.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4423473 atpI 1040294 atpI Escherichia coli CFT073 F0F1 ATP synthase subunit I NP_756525.2 4423093 R 199310 CDS NP_756526.1 26250486 1040283 complement(4424090..4424713) 1 NC_004431.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4424713 gidB 1040283 gidB Escherichia coli CFT073 16S rRNA methyltransferase GidB NP_756526.1 4424090 R 199310 CDS NP_756527.1 26250487 1040249 complement(4424777..4426666) 1 NC_004431.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4426666 gidA 1040249 gidA Escherichia coli CFT073 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_756527.1 4424777 R 199310 CDS NP_756528.1 26250488 1040246 complement(4427045..4427488) 1 NC_004431.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4427488 mioC 1040246 mioC Escherichia coli CFT073 flavodoxin NP_756528.1 4427045 R 199310 CDS NP_756529.1 26250489 1040422 complement(4427578..4428036) 1 NC_004431.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4428036 asnC 1040422 asnC Escherichia coli CFT073 DNA-binding transcriptional regulator AsnC NP_756529.1 4427578 R 199310 CDS NP_756530.1 26250490 1040297 4428188..4429180 1 NC_004431.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4429180 asnA 1040297 asnA Escherichia coli CFT073 asparagine synthetase AsnA NP_756530.1 4428188 D 199310 CDS NP_756531.1 26250491 1040417 complement(4429185..4430636) 1 NC_004431.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4430636 yieM 1040417 yieM Escherichia coli CFT073 hypothetical protein NP_756531.1 4429185 R 199310 CDS NP_756532.2 229106365 1040287 complement(4430630..4432126) 1 NC_004431.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4432126 yieN 1040287 yieN Escherichia coli CFT073 regulatory ATPase RavA NP_756532.2 4430630 R 199310 CDS NP_756533.1 26250493 1040265 4432349..4434217 1 NC_004431.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4434217 trkD 1040265 trkD Escherichia coli CFT073 potassium transport protein Kup NP_756533.1 4432349 D 199310 CDS NP_756534.2 229106364 1040419 4434384..4434803 1 NC_004431.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4434803 rbsD 1040419 rbsD Escherichia coli CFT073 D-ribose pyranase NP_756534.2 4434384 D 199310 CDS NP_756535.1 26250495 1040415 4434811..4436316 1 NC_004431.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4436316 rbsA 1040415 rbsA Escherichia coli CFT073 D-ribose transporter ATP binding protein NP_756535.1 4434811 D 199310 CDS NP_756536.1 26250496 1040281 4436321..4437286 1 NC_004431.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4437286 rbsC 1040281 rbsC Escherichia coli CFT073 ribose ABC transporter permease NP_756536.1 4436321 D 199310 CDS NP_756537.1 26250497 1040291 4437305..4438201 1 NC_004431.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4438201 rbsB 1040291 rbsB Escherichia coli CFT073 D-ribose transporter subunit RbsB NP_756537.1 4437305 D 199310 CDS NP_756538.2 161486055 1040427 4438312..4439256 1 NC_004431.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4439256 rbsK 1040427 rbsK Escherichia coli CFT073 ribokinase NP_756538.2 4438312 D 199310 CDS NP_756539.1 26250499 1040457 4439260..4440252 1 NC_004431.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4440252 rbsR 1040457 rbsR Escherichia coli CFT073 transcriptional repressor RbsR NP_756539.1 4439260 D 199310 CDS NP_756540.1 26250500 1040411 complement(4440218..4441645) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3754; Escherichia coli O157:H7 ortholog: z5255; transport protein YieO 4441645 yieO 1040411 yieO Escherichia coli CFT073 transport protein YieO NP_756540.1 4440218 R 199310 CDS NP_756541.1 26250501 1040464 complement(4441668..4442360) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3755; Escherichia coli O157:H7 ortholog: z5258; transcriptional regulator YieP 4442360 yieP 1040464 yieP Escherichia coli CFT073 transcriptional regulator YieP NP_756541.1 4441668 R 199310 CDS NP_756542.1 26250502 1036239 complement(4448165..4449004) 1 NC_004431.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4449004 yifA 1036239 yifA Escherichia coli CFT073 transcriptional regulator HdfR NP_756542.1 4448165 R 199310 CDS NP_756543.1 26250503 1040507 4449123..4449461 1 NC_004431.1 Escherichia coli K-12 ortholog: b3764; Escherichia coli O157:H7 ortholog: z5276; hypothetical protein 4449461 yifE 1040507 yifE Escherichia coli CFT073 hypothetical protein NP_756543.1 4449123 D 199310 CDS NP_756544.1 26250504 1036114 complement(4449486..4450571) 1 NC_004431.1 ORF III; Escherichia coli K-12 ortholog: b3765; Escherichia coli O157:H7 ortholog: z5277; bifunctional; hypothetical protein 4450571 yifB 1036114 yifB Escherichia coli CFT073 hypothetical protein NP_756544.1 4449486 R 199310 CDS NP_756545.1 26250505 1040473 complement(4450708..4451037) 1 NC_004431.1 Residues 1 to 95 of 109 are 100.00 pct identical to residues 1 to 95 of 516 from GenPept.129 : >gb|AAG58961.1|AE005608_2 (AE005608) 2-component regulator [Escherichia coli O157:H7 EDL933]; hypothetical protein 4451037 1040473 c4688 Escherichia coli CFT073 hypothetical protein NP_756545.1 4450708 R 199310 CDS NP_756546.1 26250506 1036343 complement(4451028..4451213) 1 NC_004431.1 hypothetical protein 4451213 1036343 c4689 Escherichia coli CFT073 hypothetical protein NP_756546.1 4451028 R 199310 CDS NP_756547.1 26250507 1040510 4451360..4451458 1 NC_004431.1 Attenuator peptide; Escherichia coli K-12 ortholog: b3766; ilvG operon leader peptide 4451458 ilvL 1040510 ilvL Escherichia coli CFT073 ilvG operon leader peptide NP_756547.1 4451360 D 199310 CDS NP_756548.1 26250508 1040479 4451598..4453244 1 NC_004431.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4453244 ilvG 1040479 ilvG Escherichia coli CFT073 acetolactate synthase 2 catalytic subunit NP_756548.1 4451598 D 199310 CDS NP_756549.1 26250509 1036240 4453241..4453504 1 NC_004431.1 Escherichia coli K-12 ortholog: b3769; Escherichia coli O157:H7 ortholog: z5280; acetolactate synthase 2 regulatory subunit 4453504 ilvM 1036240 ilvM Escherichia coli CFT073 acetolactate synthase 2 regulatory subunit NP_756549.1 4453241 D 199310 CDS NP_756550.1 26250510 1036477 4453524..4454453 1 NC_004431.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4454453 ilvE 1036477 ilvE Escherichia coli CFT073 branched-chain amino acid aminotransferase NP_756550.1 4453524 D 199310 CDS NP_756551.1 26250511 1036478 4454518..4456368 1 NC_004431.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4456368 ilvD 1036478 ilvD Escherichia coli CFT073 dihydroxy-acid dehydratase NP_756551.1 4454518 D 199310 CDS NP_756552.1 26250512 1036471 4456368..4457915 1 NC_004431.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4457915 ilvA 1036471 ilvA Escherichia coli CFT073 threonine dehydratase NP_756552.1 4456368 D 199310 CDS NP_756553.3 347357881 1035692 complement(4457912..4458886) 1 NC_004431.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4458886 ilvY 1035692 ilvY Escherichia coli CFT073 DNA-binding transcriptional regulator IlvY NP_756553.3 4457912 R 199310 CDS NP_756555.1 26250515 1036466 complement(4460473..4460754) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3775; Escherichia coli O157:H7 ortholog: z5286; peptidyl-prolyl cis-trans isomerase C 4460754 ppiC 1036466 ppiC Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase C NP_756555.1 4460473 R 199310 CDS NP_756556.1 26250516 1036347 4460841..4462862 1 NC_004431.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4462862 rep 1036347 rep Escherichia coli CFT073 ATP-dependent DNA helicase Rep NP_756556.1 4460841 D 199310 CDS NP_756557.1 26250517 1036485 complement(4462909..4464402) 1 NC_004431.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4464402 gppA 1036485 gppA Escherichia coli CFT073 guanosine pentaphosphate phosphohydrolase NP_756557.1 4462909 R 199310 CDS NP_756558.1 26250518 1036487 complement(4464529..4465794) 1 NC_004431.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4465794 rhlB 1036487 rhlB Escherichia coli CFT073 ATP-dependent RNA helicase RhlB NP_756558.1 4464529 R 199310 CDS NP_756559.1 26250519 1036612 4465820..4466254 1 NC_004431.1 TRX1; Escherichia coli K-12 ortholog: b3781; Escherichia coli O157:H7 ortholog: z5291; thioredoxin 4466254 trxA 1036612 trxA Escherichia coli CFT073 thioredoxin NP_756559.1 4465820 D 199310 CDS NP_756560.1 26250520 1036482 4466395..4466496 1 NC_004431.1 Escherichia coli K-12 ortholog: b3782; rho operon leader peptide 4466496 rhoL 1036482 rhoL Escherichia coli CFT073 rho operon leader peptide NP_756560.1 4466395 D 199310 CDS NP_756561.1 26250521 1036474 4466509..4467840 1 NC_004431.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4467840 rho 1036474 rho Escherichia coli CFT073 transcription termination factor Rho NP_756561.1 4466509 D 199310 CDS NP_756562.1 26250522 1036475 4467850..4467975 1 NC_004431.1 Residues 1 to 41 of 41 are 97.56 pct identical to residues 1 to 41 of 72 from GenPept.129 : >gb|AAG58978.1|AE005610_2 (AE005610) Z5294 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 4467975 1036475 c4703 Escherichia coli CFT073 hypothetical protein NP_756562.1 4467850 D 199310 CDS NP_756563.1 26250523 1036489 4468080..4469183 1 NC_004431.1 Escherichia coli K-12 ortholog: b3784; Escherichia coli O157:H7 ortholog: z5295; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 4469183 rfe 1036489 rfe Escherichia coli CFT073 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase NP_756563.1 4468080 D 199310 CDS NP_756564.1 26250524 1036488 4469192..4470241 1 NC_004431.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4470241 wzzE 1036488 wzzE Escherichia coli CFT073 lipopolysaccharide biosynthesis protein WzzE NP_756564.1 4469192 D 199310 CDS NP_756565.1 26250525 1036575 4470255..4471427 1 NC_004431.1 Escherichia coli K-12 ortholog: b3786; Escherichia coli O157:H7 ortholog: z5297; UDP-N-acetylglucosamine 2-epimerase 4471427 wecB 1036575 wecB Escherichia coli CFT073 UDP-N-acetylglucosamine 2-epimerase NP_756565.1 4470255 D 199310 CDS NP_756566.1 26250526 1035284 4471424..4472686 1 NC_004431.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4472686 wecC 1035284 wecC Escherichia coli CFT073 UDP-N-acetyl-D-mannosamine dehydrogenase NP_756566.1 4471424 D 199310 CDS NP_756567.1 26250527 1040140 4472686..4473753 1 NC_004431.1 Escherichia coli K-12 ortholog: b3788; Escherichia coli O157:H7 ortholog: z5299; dTDP-glucose 4,6-dehydratase 4473753 rffG 1040140 rffG Escherichia coli CFT073 dTDP-glucose 4,6-dehydratase NP_756567.1 4472686 D 199310 CDS NP_756568.1 26250528 1036425 4473772..4474653 1 NC_004431.1 Escherichia coli K-12 ortholog: b3789; Escherichia coli O157:H7 ortholog: z5300; glucose-1-phosphate thymidylyltransferase 4474653 rffH 1036425 rffH Escherichia coli CFT073 glucose-1-phosphate thymidylyltransferase NP_756568.1 4473772 D 199310 CDS NP_756569.1 26250529 1036364 4474631..4475305 1 NC_004431.1 Escherichia coli K-12 ortholog: b3790; Escherichia coli O157:H7 ortholog: z5301; TDP-fucosamine acetyltransferase 4475305 wecD 1036364 wecD Escherichia coli CFT073 TDP-fucosamine acetyltransferase NP_756569.1 4474631 D 199310 CDS NP_756570.1 26250530 1036493 4475310..4476440 1 NC_004431.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4476440 wecE 1036493 wecE Escherichia coli CFT073 TDP-4-oxo-6-deoxy-D-glucose transaminase NP_756570.1 4475310 D 199310 CDS NP_756571.1 26250531 1036479 complement(4475457..4476491) 1 NC_004431.1 hypothetical protein 4476491 1036479 c4712 Escherichia coli CFT073 hypothetical protein NP_756571.1 4475457 R 199310 CDS NP_756572.1 26250532 1036246 4476442..4477692 1 NC_004431.1 Escherichia coli K-12 ortholog: b3792; Escherichia coli O157:H7 ortholog: z5303; WzxE protein 4477692 wzxE 1036246 wzxE Escherichia coli CFT073 WzxE protein NP_756572.1 4476442 D 199310 CDS NP_756573.1 26250533 1036507 4477689..4478768 1 NC_004431.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4478768 1036507 c4714 Escherichia coli CFT073 4-alpha-L-fucosyltransferase NP_756573.1 4477689 D 199310 CDS NP_756574.1 26250534 1035934 4478765..4480117 1 NC_004431.1 enterobacterial common antigen polymerase; common antigen polymerase 4480117 wecF 1035934 wecF Escherichia coli CFT073 common antigen polymerase NP_756574.1 4478765 D 199310 CDS NP_756575.1 26250535 1035933 4480120..4480860 1 NC_004431.1 Escherichia coli K-12 ortholog: b3794; Escherichia coli O157:H7 ortholog: z5306; UDP-N-acetyl-D-mannosaminuronic acid transferase 4480860 wecG 1035933 wecG Escherichia coli CFT073 UDP-N-acetyl-D-mannosaminuronic acid transferase NP_756575.1 4480120 D 199310 CDS NP_756576.1 26250536 1036639 4481051..4482436 1 NC_004431.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4482436 yifK 1036639 yifK Escherichia coli CFT073 transport protein YifK NP_756576.1 4481051 D 199310 CDS NP_756577.1 26250537 1038202 4483122..4484357 1 NC_004431.1 Escherichia coli K-12 ortholog: b3800; Escherichia coli O157:H7 ortholog: z5313; arylsulfatase regulatory protein 4484357 aslB 1038202 aslB Escherichia coli CFT073 arylsulfatase regulatory protein NP_756577.1 4483122 D 199310 CDS NP_756578.1 26250538 1038101 complement(4484515..4486170) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3801; Escherichia coli O157:H7 ortholog: z5314; arylsulfatase 4486170 aslA 1038101 aslA Escherichia coli CFT073 arylsulfatase NP_756578.1 4484515 R 199310 CDS NP_756579.1 26250539 1036381 4486067..4486222 1 NC_004431.1 hypothetical protein 4486222 1036381 c4720 Escherichia coli CFT073 hypothetical protein NP_756579.1 4486067 D 199310 CDS NP_756580.1 26250540 1036500 complement(4486850..4488046) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3802; Escherichia coli O157:H7 ortholog: z5316; protoheme IX biogenesis protein 4488046 hemY 1036500 hemY Escherichia coli CFT073 protoheme IX biogenesis protein NP_756580.1 4486850 R 199310 CDS NP_756581.1 26250541 1036497 complement(4488049..4489266) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3803; Escherichia coli O157:H7 ortholog: z5317; uroporphyrinogen III C-methyltransferase 4489266 hemX 1036497 hemX Escherichia coli CFT073 uroporphyrinogen III C-methyltransferase NP_756581.1 4488049 R 199310 CDS NP_756582.1 26250542 1035988 complement(4489288..4490028) 1 NC_004431.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4490028 hemD 1035988 hemD Escherichia coli CFT073 uroporphyrinogen-III synthase NP_756582.1 4489288 R 199310 CDS NP_756583.1 26250543 1036562 complement(4490025..4490987) 1 NC_004431.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4490987 hemC 1036562 hemC Escherichia coli CFT073 porphobilinogen deaminase NP_756583.1 4490025 R 199310 CDS NP_756584.1 26250544 1035601 4491353..4493899 1 NC_004431.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4493899 cyaA 1035601 cyaA Escherichia coli CFT073 adenylate cyclase NP_756584.1 4491353 D 199310 CDS NP_756585.1 26250545 1035651 complement(4493939..4494259) 1 NC_004431.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4494259 cyaY 1035651 cyaY Escherichia coli CFT073 frataxin-like protein NP_756585.1 4493939 R 199310 CDS NP_756586.1 26250546 1037438 complement(4494307..4495626) 1 NC_004431.1 Residues 254 to 430 of 439 are 44.06 pct identical to residues 493 to 667 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 4495626 1037438 c4727 Escherichia coli CFT073 hypothetical protein NP_756586.1 4494307 R 199310 CDS NP_756587.1 26250547 1038919 complement(4495623..4497122) 1 NC_004431.1 Residues 11 to 499 of 499 are 62.62 pct identical to residues 1 to 495 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 4497122 1038919 c4728 Escherichia coli CFT073 hypothetical protein NP_756587.1 4495623 R 199310 CDS NP_756588.1 26250548 1035937 4497281..4497484 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5325; hypothetical protein 4497484 1035937 c4729 Escherichia coli CFT073 hypothetical protein NP_756588.1 4497281 D 199310 CDS NP_756589.2 161486052 1035956 4497521..4498345 1 NC_004431.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4498345 dapF 1035956 dapF Escherichia coli CFT073 diaminopimelate epimerase NP_756589.2 4497521 D 199310 CDS NP_756590.1 26250550 1037537 4498342..4499049 1 NC_004431.1 Escherichia coli K-12 ortholog: b3810; Escherichia coli O157:H7 ortholog: z5327; hypothetical protein 4499049 yigA 1037537 yigA Escherichia coli CFT073 hypothetical protein NP_756590.1 4498342 D 199310 CDS NP_756591.1 26250551 1035725 4499046..4499942 1 NC_004431.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4499942 xerC 1035725 xerC Escherichia coli CFT073 site-specific tyrosine recombinase XerC NP_756591.1 4499046 D 199310 CDS NP_756592.1 26250552 1038182 4499942..4500658 1 NC_004431.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4500658 yigB 1038182 yigB Escherichia coli CFT073 flavin mononucleotide phosphatase NP_756592.1 4499942 D 199310 CDS NP_756593.2 161486051 1035765 4500742..4502904 1 NC_004431.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4502904 uvrD 1035765 uvrD Escherichia coli CFT073 DNA-dependent helicase II NP_756593.2 4500742 D 199310 CDS NP_756594.1 26250554 1038058 complement(4502959..4503861) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5331; hypothetical protein 4503861 1038058 c4735 Escherichia coli CFT073 hypothetical protein NP_756594.1 4502959 R 199310 CDS NP_756595.1 26250555 1035299 complement(4503944..4504708) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5332; hypothetical protein 4504708 1035299 c4736 Escherichia coli CFT073 hypothetical protein NP_756595.1 4503944 R 199310 CDS NP_756596.2 161486050 1038460 4505078..4506028 1 NC_004431.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4506028 corA 1038460 corA Escherichia coli CFT073 magnesium/nickel/cobalt transporter CorA NP_756596.2 4505078 D 199310 CDS NP_756597.1 26250557 1037641 complement(4506064..4506561) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5334; hypothetical protein 4506561 1037641 c4738 Escherichia coli CFT073 hypothetical protein NP_756597.1 4506064 R 199310 CDS NP_756598.1 26250558 1035936 complement(4506558..4507406) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5335; hypothetical protein 4507406 1035936 c4739 Escherichia coli CFT073 hypothetical protein NP_756598.1 4506558 R 199310 CDS NP_756599.1 26250559 1035405 complement(4507717..4508607) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3819; Escherichia coli O157:H7 ortholog: z5340; protein rarD 4508607 rarD 1035405 rarD Escherichia coli CFT073 protein rarD NP_756599.1 4507717 R 199310 CDS NP_756600.2 161486049 1038510 complement(4508659..4509126) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3820; Escherichia coli O157:H7 ortholog: z5341; hypothetical protein 4509126 yigI 1038510 yigI Escherichia coli CFT073 hypothetical protein NP_756600.2 4508659 R 199310 CDS NP_756601.1 26250561 1036509 4509290..4510159 1 NC_004431.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4510159 pldA 1036509 pldA Escherichia coli CFT073 phospholipase A NP_756601.1 4509290 D 199310 CDS NP_756602.1 26250562 1038737 4510163..4510324 1 NC_004431.1 hypothetical protein 4510324 1038737 c4743 Escherichia coli CFT073 hypothetical protein NP_756602.1 4510163 D 199310 CDS NP_756603.1 26250563 1038269 4510278..4512113 1 NC_004431.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4512113 recQ 1038269 recQ Escherichia coli CFT073 ATP-dependent DNA helicase RecQ NP_756603.1 4510278 D 199310 CDS NP_756604.1 26250564 1035003 4512177..4512797 1 NC_004431.1 Residues 1 to 206 of 206 are 99.02 pct identical to residues 1 to 206 of 206 from SwissProt.40 : >sp|P27846|RHTC_ECOLI Threonine efflux protein; threonine efflux system 4512797 1035003 c4745 Escherichia coli CFT073 threonine efflux system NP_756604.1 4512177 D 199310 CDS NP_756605.1 26250565 1040456 complement(4512858..4513478) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3824; Escherichia coli O157:H7 ortholog: z5345; homoserine/homoserine lactone efflux protein 4513478 rhtB 1040456 rhtB Escherichia coli CFT073 homoserine/homoserine lactone efflux protein NP_756605.1 4512858 R 199310 CDS NP_756606.1 26250566 1035613 4513589..4514611 1 NC_004431.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4514611 pldB 1035613 pldB Escherichia coli CFT073 lysophospholipase L2 NP_756606.1 4513589 D 199310 CDS NP_756607.1 26250567 1037281 4514556..4515419 1 NC_004431.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4515419 1037281 c4748 Escherichia coli CFT073 sugar phosphatase NP_756607.1 4514556 D 199310 CDS NP_756608.1 26250568 1038265 4515420..4516394 1 NC_004431.1 Escherichia coli K-12 ortholog: b3827; Escherichia coli O157:H7 ortholog: z5348; membrane protein yigM 4516394 yigM 1038265 yigM Escherichia coli CFT073 membrane protein yigM NP_756608.1 4515420 D 199310 CDS NP_756609.1 26250569 1035353 complement(4516282..4517235) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3828; Escherichia coli O157:H7 ortholog: z5349; transcriptional activator protein metR 4517235 metR 1035353 metR Escherichia coli CFT073 transcriptional activator protein metR NP_756609.1 4516282 R 199310 CDS NP_756610.1 26250570 1034999 4517353..4519614 1 NC_004431.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4519614 metE 1034999 metE Escherichia coli CFT073 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase NP_756610.1 4517353 D 199310 CDS NP_756611.1 26250571 1037193 complement(4519621..4519746) 1 NC_004431.1 hypothetical protein 4519746 1037193 c4752 Escherichia coli CFT073 hypothetical protein NP_756611.1 4519621 R 199310 CDS NP_756612.1 26250572 1036655 complement(4519783..4520043) 1 NC_004431.1 Residues 11 to 77 of 86 are 34.32 pct identical to residues 32 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 4520043 1036655 c4753 Escherichia coli CFT073 hypothetical protein NP_756612.1 4519783 R 199310 CDS NP_756613.1 26250573 1035111 complement(4520103..4520360) 1 NC_004431.1 Residues 6 to 73 of 85 are 33.82 pct identical to residues 31 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 4520360 1035111 c4754 Escherichia coli CFT073 hypothetical protein NP_756613.1 4520103 R 199310 CDS NP_756614.1 26250574 1035125 complement(4520357..4521046) 1 NC_004431.1 Residues 31 to 227 of 229 are 44.17 pct identical to residues 188 to 384 of 386 from GenPept.129 : >emb|CAD16923.1| (AL646075) PROBABLE TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]; hypothetical protein 4521046 1035125 c4755 Escherichia coli CFT073 hypothetical protein NP_756614.1 4520357 R 199310 CDS NP_756615.1 26250575 1038915 4521725..4521856 1 NC_004431.1 hypothetical protein 4521856 1038915 c4756 Escherichia coli CFT073 hypothetical protein NP_756615.1 4521725 D 199310 CDS NP_756616.1 26250576 1034996 4521963..4522532 1 NC_004431.1 Residues 5 to 189 of 189 are 38.37 pct identical to residues 1 to 184 of 184 from GenPept.129 : >emb|CAD22377.1| (AX343668) unnamed protein product [Brevibacillus brevis]; hypothetical protein 4522532 1034996 c4757 Escherichia coli CFT073 hypothetical protein NP_756616.1 4521963 D 199310 CDS NP_756617.1 26250577 1038189 4522574..4524082 1 NC_004431.1 EIIBC-Glc; Escherichia coli K-12 ortholog: b1101; Escherichia coli O157:H7 ortholog: z1740; PTS system, glucose-specific IIBC component 4524082 1038189 c4758 Escherichia coli CFT073 PTS system, glucose-specific IIBC component NP_756617.1 4522574 D 199310 CDS NP_756618.1 26250578 1034973 4524133..4526130 1 NC_004431.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4526130 1034973 c4759 Escherichia coli CFT073 transketolase NP_756618.1 4524133 D 199310 CDS NP_756619.1 26250579 1038724 complement(4526160..4527005) 1 NC_004431.1 Residues 10 to 262 of 281 are 28.34 pct identical to residues 15 to 268 of 287 from GenPept.129 : >dbj|BAB06394.1| (AP001516) transcriptional regulator (RpiR family) [Bacillus halodurans]; hypothetical protein 4527005 1038724 c4760 Escherichia coli CFT073 hypothetical protein NP_756619.1 4526160 R 199310 CDS NP_756620.1 26250580 1035776 complement(4527206..4528111) 1 NC_004431.1 Residues 4 to 297 of 301 are 34.35 pct identical to residues 3 to 296 of 310 from MG1655 : b1659; hypothetical protein 4528111 1035776 c4761 Escherichia coli CFT073 hypothetical protein NP_756620.1 4527206 R 199310 CDS NP_756621.1 26250581 1035232 complement(4528189..4529412) 1 NC_004431.1 Residues 14 to 395 of 407 are 28.42 pct identical to residues 27 to 419 of 445 from GenPept.129 : >dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans]; permease 4529412 1035232 c4762 Escherichia coli CFT073 permease NP_756621.1 4528189 R 199310 CDS NP_756622.1 26250582 1037889 complement(4529438..4529827) 1 NC_004431.1 Residues 6 to 122 of 129 are 38.33 pct identical to residues 474 to 593 of 619 from GenPept.129 : >dbj|BAB53245.1| (AP003010) glutamyl-tRNA(Gln) amidotransferase subunit A [Mesorhizobium loti]; hypothetical protein 4529827 1037889 c4763 Escherichia coli CFT073 hypothetical protein NP_756622.1 4529438 R 199310 CDS NP_756623.1 26250583 1034977 complement(4529844..4530800) 1 NC_004431.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4530800 1034977 c4764 Escherichia coli CFT073 carbamate kinase NP_756623.1 4529844 R 199310 CDS NP_756624.1 26250584 1036511 complement(4530793..4532268) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0321; Escherichia coli O157:H7 ortholog: z0410; hypothetical protein 4532268 1036511 c4765 Escherichia coli CFT073 hypothetical protein NP_756624.1 4530793 R 199310 CDS NP_756625.1 26250585 1037198 4530799..4530939 1 NC_004431.1 hypothetical protein 4530939 1037198 c4766 Escherichia coli CFT073 hypothetical protein NP_756625.1 4530799 D 199310 CDS NP_756626.1 26250586 1035977 complement(4532214..4533773) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0320; Escherichia coli O157:H7 ortholog: z0409; hypothetical protein 4533773 1035977 c4767 Escherichia coli CFT073 hypothetical protein NP_756626.1 4532214 R 199310 CDS NP_756627.1 26250587 1035657 complement(4533868..4534728) 1 NC_004431.1 Residues 24 to 278 of 286 are 25.37 pct identical to residues 18 to 274 of 287 from GenPept.129 : >gb|AAG54663.1|AE005210_7 (AE005210) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 4534728 1035657 c4768 Escherichia coli CFT073 hypothetical protein NP_756627.1 4533868 R 199310 CDS NP_756628.1 26250588 1035239 complement(4534734..4535333) 1 NC_004431.1 Residues 1 to 197 of 199 are 56.78 pct identical to residues 34 to 232 of 233 from GenPept.129 : >dbj|BAB53241.1| (AP003010) hypothetical protein [Mesorhizobium loti]; hypothetical protein 4535333 1035239 c4769 Escherichia coli CFT073 hypothetical protein NP_756628.1 4534734 R 199310 CDS NP_756629.1 26250589 1038242 complement(4535368..4535517) 1 NC_004431.1 hypothetical protein 4535517 1038242 c4770 Escherichia coli CFT073 hypothetical protein NP_756629.1 4535368 R 199310 CDS NP_756630.1 26250590 1035267 complement(4535659..4536534) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5352; carboxymethylenebutenolidase 4536534 1035267 c4771 Escherichia coli CFT073 carboxymethylenebutenolidase NP_756630.1 4535659 R 199310 CDS NP_756632.2 161486048 1038346 4536730..4537494 1 NC_004431.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4537494 udp 1038346 udp Escherichia coli CFT073 uridine phosphorylase NP_756632.2 4536730 D 199310 CDS NP_756631.1 26250591 1037710 complement(4536775..4537509) 1 NC_004431.1 hypothetical protein 4537509 1037710 c4772 Escherichia coli CFT073 hypothetical protein NP_756631.1 4536775 R 199310 CDS NP_756633.1 26250593 1036472 complement(4537529..4539019) 1 NC_004431.1 Residues 19 to 496 of 496 are 46.99 pct identical to residues 16 to 493 of 504 from GenPept.129 : >dbj|BAB05728.1| (AP001514) BH2009; unknown conserved protein in others [Bacillus halodurans]; hypothetical protein 4539019 1036472 c4774 Escherichia coli CFT073 hypothetical protein NP_756633.1 4537529 R 199310 CDS NP_756634.1 26250594 1035667 complement(4539032..4539541) 1 NC_004431.1 Residues 52 to 165 of 169 are 31.66 pct identical to residues 28 to 144 of 147 from GenPept.129 : >gb|AAL94188.1| (AE010513) unknown [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 4539541 1035667 c4775 Escherichia coli CFT073 hypothetical protein NP_756634.1 4539032 R 199310 CDS NP_756635.1 26250595 1038104 complement(4539555..4540529) 1 NC_004431.1 Residues 31 to 322 of 324 are 33.44 pct identical to residues 15 to 307 of 308 from GenPept.129 : >gb|AAL94187.1| (AE010513) RecA protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 4540529 1038104 c4776 Escherichia coli CFT073 hypothetical protein NP_756635.1 4539555 R 199310 CDS NP_756636.1 26250596 1036819 complement(4540554..4541183) 1 NC_004431.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4541183 1036819 c4777 Escherichia coli CFT073 2-dehydro-3-deoxy-6-phosphogalactonate aldolase NP_756636.1 4540554 R 199310 CDS NP_756637.1 26250597 1035670 complement(4541173..4542177) 1 NC_004431.1 Residues 7 to 319 of 334 are 34.38 pct identical to residues 5 to 289 of 292 from MG1655 : b3693; hypothetical protein 4542177 1035670 c4778 Escherichia coli CFT073 hypothetical protein NP_756637.1 4541173 R 199310 CDS NP_756638.1 26250598 1035310 complement(4542201..4543055) 1 NC_004431.1 Residues 40 to 273 of 284 are 32.36 pct identical to residues 2 to 242 of 254 from GenPept.129 : >emb|CAC40602.1| (AL591857) IclR-family transcriptional regulatory protein [Streptomyces coelicolor]; transcriptional regulator 4543055 1035310 c4779 Escherichia coli CFT073 transcriptional regulator NP_756638.1 4542201 R 199310 CDS NP_756639.1 26250599 1038725 4543132..4543290 1 NC_004431.1 hypothetical protein 4543290 1038725 c4780 Escherichia coli CFT073 hypothetical protein NP_756639.1 4543132 D 199310 CDS NP_756640.1 26250600 1035262 4543185..4544612 1 NC_004431.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4544612 yigN 1035262 yigN Escherichia coli CFT073 DNA recombination protein RmuC NP_756640.1 4543185 D 199310 CDS NP_756641.1 26250601 1038327 4544707..4545462 1 NC_004431.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4545462 ubiE 1038327 ubiE Escherichia coli CFT073 ubiquinone/menaquinone biosynthesis methyltransferase NP_756641.1 4544707 D 199310 CDS NP_756642.1 26250602 1035938 4545431..4546081 1 NC_004431.1 Escherichia coli K-12 ortholog: b3834; Escherichia coli O157:H7 ortholog: z5356; hypothetical protein 4546081 yigP 1035938 yigP Escherichia coli CFT073 hypothetical protein NP_756642.1 4545431 D 199310 CDS NP_756643.1 26250603 1038139 4546078..4547718 1 NC_004431.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4547718 ubiB 1038139 ubiB Escherichia coli CFT073 ubiquinone biosynthesis protein UbiB NP_756643.1 4546078 D 199310 CDS NP_756644.1 26250604 1036512 4547755..4548066 1 NC_004431.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4548066 tatA 1036512 tatA Escherichia coli CFT073 twin arginine translocase protein A NP_756644.1 4547755 D 199310 CDS NP_756645.1 26250605 1037187 4548070..4548585 1 NC_004431.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4548585 1037187 c4786 Escherichia coli CFT073 sec-independent translocase NP_756645.1 4548070 D 199310 CDS NP_756646.1 26250606 1035673 4548588..4549364 1 NC_004431.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4549364 yigU 1035673 yigU Escherichia coli CFT073 twin-arginine protein translocation system subunit TatC NP_756646.1 4548588 D 199310 CDS NP_756647.1 26250607 1035668 4549394..4550188 1 NC_004431.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4550188 yigW 1035668 yigW Escherichia coli CFT073 DNase TatD NP_756647.1 4549394 D 199310 CDS NP_756648.1 26250608 1035846 complement(4550185..4550673) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3842; Escherichia coli O157:H7 ortholog: z5362; transcriptional activator RfaH 4550673 rfaH 1035846 rfaH Escherichia coli CFT073 transcriptional activator RfaH NP_756648.1 4550185 R 199310 CDS NP_756649.1 26250609 1035828 4550840..4552333 1 NC_004431.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4552333 yigC 1035828 yigC Escherichia coli CFT073 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_756649.1 4550840 D 199310 CDS NP_756650.2 161486047 1035669 4552379..4553080 1 NC_004431.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4553080 fre 1035669 fre Escherichia coli CFT073 FMN reductase NP_756650.2 4552379 D 199310 CDS NP_756651.1 26250611 1038239 complement(4553272..4554435) 1 NC_004431.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4554435 fadA 1038239 fadA Escherichia coli CFT073 3-ketoacyl-CoA thiolase NP_756651.1 4553272 R 199310 CDS NP_756652.2 161486046 1035892 complement(4554445..4556634) 1 NC_004431.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4556634 fadB 1035892 fadB Escherichia coli CFT073 multifunctional fatty acid oxidation complex subunit alpha NP_756652.2 4554445 R 199310 CDS NP_756653.1 26250613 1035710 4556824..4558155 1 NC_004431.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4558155 pepQ 1035710 pepQ Escherichia coli CFT073 proline dipeptidase NP_756653.1 4556824 D 199310 CDS NP_756654.1 26250614 1036031 4558152..4558769 1 NC_004431.1 Escherichia coli K-12 ortholog: b3848; Escherichia coli O157:H7 ortholog: z5370; hypothetical protein 4558769 yigZ 1036031 yigZ Escherichia coli CFT073 hypothetical protein NP_756654.1 4558152 D 199310 CDS NP_756655.1 26250615 1035672 4558808..4560259 1 NC_004431.1 Escherichia coli K-12 ortholog: b3849; Escherichia coli O157:H7 ortholog: z5371; potassium transporter 4560259 trkH 1035672 trkH Escherichia coli CFT073 potassium transporter NP_756655.1 4558808 D 199310 CDS NP_756656.1 26250616 1038229 4560271..4560816 1 NC_004431.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4560816 hemG 1038229 hemG Escherichia coli CFT073 protoporphyrinogen oxidase NP_756656.1 4560271 D 199310 CDS NP_756657.1 26250617 1035666 complement(4566397..4566924) 1 NC_004431.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4566924 mobB 1035666 mobB Escherichia coli CFT073 molybdopterin-guanine dinucleotide biosynthesis protein B NP_756657.1 4566397 R 199310 CDS NP_756658.1 26250618 1035939 complement(4566906..4567490) 1 NC_004431.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4567490 mobA 1035939 mobA Escherichia coli CFT073 molybdopterin-guanine dinucleotide biosynthesis protein MobA NP_756658.1 4566906 R 199310 CDS NP_756659.1 26250619 1038221 4567530..4567829 1 NC_004431.1 Escherichia coli K-12 ortholog: b3858; Escherichia coli O157:H7 ortholog: z5390; hypothetical protein 4567829 yihD 1038221 yihD Escherichia coli CFT073 hypothetical protein NP_756659.1 4567530 D 199310 CDS NP_756660.1 26250620 1038199 4567906..4568892 1 NC_004431.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4568892 yihE 1038199 yihE Escherichia coli CFT073 serine/threonine protein kinase NP_756660.1 4567906 D 199310 CDS NP_756661.1 26250621 1036525 4568909..4569535 1 NC_004431.1 Escherichia coli K-12 ortholog: b3860; Escherichia coli O157:H7 ortholog: z5392; periplasmic protein disulfide isomerase I 4569535 dsbA 1036525 dsbA Escherichia coli CFT073 periplasmic protein disulfide isomerase I NP_756661.1 4568909 D 199310 CDS NP_756662.1 26250622 1036045 4569560..4569700 1 NC_004431.1 hypothetical protein 4569700 1036045 c4805 Escherichia coli CFT073 hypothetical protein NP_756662.1 4569560 D 199310 CDS NP_756663.1 26250623 1035727 4569648..4571120 1 NC_004431.1 Escherichia coli K-12 ortholog: b3861; Escherichia coli O157:H7 ortholog: z5393; hypothetical protein 4571120 yihF 1035727 yihF Escherichia coli CFT073 hypothetical protein NP_756663.1 4569648 D 199310 CDS NP_756664.2 229106363 1038235 complement(4571161..4572093) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3862; Escherichia coli O157:H7 ortholog: z5394; acyltransferase 4572093 yihG 1038235 yihG Escherichia coli CFT073 acyltransferase NP_756664.2 4571161 R 199310 CDS NP_756665.1 26250625 1038192 complement(4572213..4572455) 1 NC_004431.1 hypothetical protein 4572455 1038192 c4808 Escherichia coli CFT073 hypothetical protein NP_756665.1 4572213 R 199310 CDS NP_756666.1 26250626 1038204 complement(4575461..4575610) 1 NC_004431.1 hypothetical protein 4575610 1038204 c4811 Escherichia coli CFT073 hypothetical protein NP_756666.1 4575461 R 199310 CDS NP_756667.2 161486045 1038231 complement(4575624..4576256) 1 NC_004431.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4576256 engB 1038231 engB Escherichia coli CFT073 ribosome biogenesis GTP-binding protein YsxC NP_756667.2 4575624 R 199310 CDS NP_756668.1 26250628 1036527 complement(4576275..4576415) 1 NC_004431.1 hypothetical protein 4576415 1036527 c4813 Escherichia coli CFT073 hypothetical protein NP_756668.1 4576275 R 199310 CDS NP_756669.1 26250629 1038201 complement(4576723..4576869) 1 NC_004431.1 hypothetical protein 4576869 1038201 c4814 Escherichia coli CFT073 hypothetical protein NP_756669.1 4576723 R 199310 CDS NP_756670.1 26250630 1036054 4576838..4577347 1 NC_004431.1 Escherichia coli K-12 ortholog: b3866; Escherichia coli O157:H7 ortholog: z5402; hypothetical protein 4577347 yihI 1036054 yihI Escherichia coli CFT073 hypothetical protein NP_756670.1 4576838 D 199310 CDS NP_756671.2 161486044 1038210 4577536..4578909 1 NC_004431.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4578909 hemN 1038210 hemN Escherichia coli CFT073 coproporphyrinogen III oxidase NP_756671.2 4577536 D 199310 CDS NP_756672.2 161486043 1035991 complement(4579364..4580773) 1 NC_004431.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4580773 glnG 1035991 glnG Escherichia coli CFT073 nitrogen regulation protein NR(I) NP_756672.2 4579364 R 199310 CDS NP_756673.1 26250633 1035716 complement(4580785..4581834) 1 NC_004431.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4581834 glnL 1035716 glnL Escherichia coli CFT073 nitrogen regulation protein NR(II) NP_756673.1 4580785 R 199310 CDS NP_756674.1 26250634 1036016 complement(4582008..4583417) 1 NC_004431.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4583417 glnA 1036016 glnA Escherichia coli CFT073 glutamine synthetase NP_756674.1 4582008 R 199310 CDS NP_756675.1 26250635 1036449 4583790..4585613 1 NC_004431.1 Tyrosine phosphorylated protein A; Escherichia coli K-12 ortholog: b3871; Escherichia coli O157:H7 ortholog: z5407; GTP-binding protein 4585613 yihK 1036449 yihK Escherichia coli CFT073 GTP-binding protein NP_756675.1 4583790 D 199310 CDS NP_756676.1 26250636 1040466 4585831..4586541 1 NC_004431.1 Escherichia coli K-12 ortholog: b3872; Escherichia coli O157:H7 ortholog: z5408; transcriptional regulator YihL 4586541 yihL 1040466 yihL Escherichia coli CFT073 transcriptional regulator YihL NP_756676.1 4585831 D 199310 CDS NP_756677.1 26250637 1036007 4586549..4587529 1 NC_004431.1 Escherichia coli K-12 ortholog: b3873; Escherichia coli O157:H7 ortholog: z5409; hypothetical protein 4587529 yihM 1036007 yihM Escherichia coli CFT073 hypothetical protein NP_756677.1 4586549 D 199310 CDS NP_756678.1 26250638 1036017 4587631..4588896 1 NC_004431.1 Escherichia coli K-12 ortholog: b3874; Escherichia coli O157:H7 ortholog: z5410; hypothetical protein 4588896 yihN 1036017 yihN Escherichia coli CFT073 hypothetical protein NP_756678.1 4587631 D 199310 CDS NP_756679.1 26250639 1038216 complement(4588956..4589744) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3884; Escherichia coli O157:H7 ortholog: z5422; transcriptional regulator YihW 4589744 yihW 1038216 yihW Escherichia coli CFT073 transcriptional regulator YihW NP_756679.1 4588956 R 199310 CDS NP_756680.3 347357880 1038180 complement(4589784..4590731) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3883; Escherichia coli O157:H7 ortholog: z5421; sugar kinase yihV 4590731 yihV 1038180 yihV Escherichia coli CFT073 sugar kinase yihV NP_756680.3 4589784 R 199310 CDS NP_756681.1 26250641 1038185 4590652..4591731 1 NC_004431.1 Escherichia coli K-12 ortholog: b3882; Escherichia coli O157:H7 ortholog: z5420; oxidoreductase yihU 4591731 yihU 1038185 yihU Escherichia coli CFT073 oxidoreductase yihU NP_756681.1 4590652 D 199310 CDS NP_756682.1 26250642 1038200 4591756..4592643 1 NC_004431.1 Escherichia coli K-12 ortholog: b3881; Escherichia coli O157:H7 ortholog: z5418; hypothetical protein 4592643 yihT 1038200 yihT Escherichia coli CFT073 hypothetical protein NP_756682.1 4591756 D 199310 CDS NP_756683.1 26250643 1035975 4592676..4593686 1 NC_004431.1 Zinc binding; Residues 29 to 330 of 336 are 33.64 pct identical to residues 45 to 365 of 368 from GenPept.129 : >gb|AAK71492.1| (AY037946) sorbitol dehydrogenase [Prunus cerasus]; dehydrogenase 4593686 1035975 c4828 Escherichia coli CFT073 dehydrogenase NP_756683.1 4592676 D 199310 CDS NP_756684.1 26250644 1038181 4593756..4595189 1 NC_004431.1 Residues 30 to 455 of 477 are 22.60 pct identical to residues 62 to 476 of 486 from GenPept.129 : >emb|CAC11594.1| (AL445064) sugar transport protein related protein [Thermoplasma acidophilum]; hypothetical protein 4595189 1038181 c4829 Escherichia coli CFT073 hypothetical protein NP_756684.1 4593756 D 199310 CDS NP_756685.1 26250645 1036448 4595288..4596637 1 NC_004431.1 Escherichia coli K-12 ortholog: b1981; Escherichia coli O157:H7 ortholog: z3138; shikimate transporter 4596637 1036448 c4830 Escherichia coli CFT073 shikimate transporter NP_756685.1 4595288 D 199310 CDS NP_756686.1 26250646 1038211 4596570..4597514 1 NC_004431.1 Residues 46 to 310 of 314 are 43.39 pct identical to residues 4 to 259 of 262 from GenPept.129 : >emb|CAB42038.1| (AL049754) hypothetical protein [Streptomyces coelicolor A3(2)]; hypothetical protein 4597514 1038211 c4831 Escherichia coli CFT073 hypothetical protein NP_756686.1 4596570 D 199310 CDS NP_756687.3 347357879 1038207 4597634..4598254 1 NC_004431.1 Escherichia coli K-12 ortholog: b3885; Escherichia coli O157:H7 ortholog: z5424; phosphatase 4598254 yihX 1038207 yihX Escherichia coli CFT073 phosphatase NP_756687.3 4597634 D 199310 CDS NP_756688.1 26250648 1036574 4598248..4599120 1 NC_004431.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4599120 rbn 1036574 rbn Escherichia coli CFT073 ribonuclease BN NP_756688.1 4598248 D 199310 CDS NP_756689.1 26250649 1036075 4599117..4599554 1 NC_004431.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4599554 yihZ 1036075 yihZ Escherichia coli CFT073 D-tyrosyl-tRNA(Tyr) deacylase NP_756689.1 4599117 D 199310 CDS NP_756690.1 26250650 1037527 4599551..4600540 1 NC_004431.1 Escherichia coli K-12 ortholog: b3888; Escherichia coli O157:H7 ortholog: z5427; hypothetical protein 4600540 yiiD 1037527 yiiD Escherichia coli CFT073 hypothetical protein NP_756690.1 4599551 D 199310 CDS NP_756691.1 26250651 1038198 complement(4600604..4601524) 1 NC_004431.1 Residues 5 to 303 of 306 are 74.91 pct identical to residues 1 to 299 of 309 from GenPept.129 : >emb|CAD09594.1| (AL627279) lipase [Salmonella enterica subsp. enterica serovar Typhi]; lipase 4601524 1038198 c4836 Escherichia coli CFT073 lipase NP_756691.1 4600604 R 199310 CDS NP_756692.1 26250652 1034926 4601742..4602053 1 NC_004431.1 Residues 2 to 103 of 103 are 41.17 pct identical to residues 4 to 105 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae]; hypothetical protein 4602053 1034926 c4837 Escherichia coli CFT073 hypothetical protein NP_756692.1 4601742 D 199310 CDS NP_756693.1 26250653 1040465 4602054..4602344 1 NC_004431.1 Residues 13 to 94 of 96 are 87.80 pct identical to residues 1 to 82 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) bacterial regulatory protein, merR family [Salmonella typhimurium LT2]; hypothetical protein 4602344 1040465 c4838 Escherichia coli CFT073 hypothetical protein NP_756693.1 4602054 D 199310 CDS NP_756694.1 26250654 1040462 4602703..4602981 1 NC_004431.1 hypothetical protein 4602981 1040462 c4839 Escherichia coli CFT073 hypothetical protein NP_756694.1 4602703 D 199310 CDS NP_756695.1 26250655 1040452 4603350..4603595 1 NC_004431.1 Escherichia coli K-12 ortholog: b3889; Escherichia coli O157:H7 ortholog: z5431; hypothetical protein 4603595 yiiE 1040452 yiiE Escherichia coli CFT073 hypothetical protein NP_756695.1 4603350 D 199310 CDS NP_756696.1 26250656 1040447 complement(4603811..4604740) 1 NC_004431.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4604740 fdhE 1040447 fdhE Escherichia coli CFT073 formate dehydrogenase accessory protein FdhE NP_756696.1 4603811 R 199310 CDS NP_756697.1 26250657 1040444 complement(4604737..4605372) 1 NC_004431.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4605372 fdoI 1040444 fdoI Escherichia coli CFT073 formate dehydrogenase-O subunit gamma NP_756697.1 4604737 R 199310 CDS NP_756698.1 26250658 1040442 complement(4605369..4606271) 1 NC_004431.1 Iron-sulfur subunit; Escherichia coli K-12 ortholog: b3893; Escherichia coli O157:H7 ortholog: z5435; formate dehydrogenase-O beta subunit 4606271 fdoH 1040442 fdoH Escherichia coli CFT073 formate dehydrogenase-O beta subunit NP_756698.1 4605369 R 199310 CDS NP_756699.1 26250659 1040441 complement(4606284..4609334) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3894; Escherichia coli O157:H7 ortholog: z5436; formate dehydrogenase-O, major subunit 4609334 fdoG 1040441 fdoG Escherichia coli CFT073 formate dehydrogenase-O, major subunit NP_756699.1 4606284 R 199310 CDS NP_756700.1 26250660 1040439 4608966..4609592 1 NC_004431.1 hypothetical protein 4609592 1040439 c4846 Escherichia coli CFT073 hypothetical protein NP_756700.1 4608966 D 199310 CDS NP_756701.1 26250661 1040436 4609528..4610361 1 NC_004431.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4610361 fdhD 1040436 fdhD Escherichia coli CFT073 formate dehydrogenase accessory protein NP_756701.1 4609528 D 199310 CDS NP_756702.1 26250662 1040300 4610449..4611003 1 NC_004431.1 Residues 1 to 163 of 184 are 74.51 pct identical to residues 139 to 346 of 351 from MG1655 : b3896; hypothetical protein 4611003 1040300 c4848 Escherichia coli CFT073 hypothetical protein NP_756702.1 4610449 D 199310 CDS NP_756703.1 26250663 1040253 4611357..4612730 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5444; glycoporin 4612730 1040253 c4849 Escherichia coli CFT073 glycoporin NP_756703.1 4611357 D 199310 CDS NP_756704.1 26250664 1040252 complement(4612771..4613085) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3901; Escherichia coli O157:H7 ortholog: z5445; hypothetical protein 4613085 yiiL 1040252 yiiL Escherichia coli CFT073 hypothetical protein NP_756704.1 4612771 R 199310 CDS NP_756705.1 26250665 1040225 complement(4613095..4614012) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3902; Escherichia coli O157:H7 ortholog: z5446; rhamnulose-1-phosphate aldolase 4614012 rhaD 1040225 rhaD Escherichia coli CFT073 rhamnulose-1-phosphate aldolase NP_756705.1 4613095 R 199310 CDS NP_756706.1 26250666 1040224 complement(4614380..4615645) 1 NC_004431.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4615645 rhaA 1040224 rhaA Escherichia coli CFT073 L-rhamnose isomerase NP_756706.1 4614380 R 199310 CDS NP_756707.1 26250667 1040218 complement(4615636..4617105) 1 NC_004431.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4617105 rhaB 1040218 rhaB Escherichia coli CFT073 rhamnulokinase NP_756707.1 4615636 R 199310 CDS NP_756708.1 26250668 1040216 4617184..4617333 1 NC_004431.1 hypothetical protein 4617333 1040216 c4854 Escherichia coli CFT073 hypothetical protein NP_756708.1 4617184 D 199310 CDS NP_756709.1 26250669 1040213 4617393..4618229 1 NC_004431.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4618229 rhaS 1040213 rhaS Escherichia coli CFT073 transcriptional activator RhaS NP_756709.1 4617393 D 199310 CDS NP_756710.1 26250670 1040212 4618192..4619151 1 NC_004431.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4619151 rhaR 1040212 rhaR Escherichia coli CFT073 transcriptional activator RhaR NP_756710.1 4618192 D 199310 CDS NP_756711.1 26250671 1040211 complement(4619148..4620182) 1 NC_004431.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4620182 rhaT 1040211 rhaT Escherichia coli CFT073 rhamnose-proton symporter NP_756711.1 4619148 R 199310 CDS NP_756712.1 26250672 1040210 4620147..4620314 1 NC_004431.1 hypothetical protein 4620314 1040210 c4858 Escherichia coli CFT073 hypothetical protein NP_756712.1 4620147 D 199310 CDS NP_756713.1 26250673 1040208 4620462..4621088 1 NC_004431.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4621088 sodA 1040208 sodA Escherichia coli CFT073 superoxide dismutase NP_756713.1 4620462 D 199310 CDS NP_756714.1 26250674 1040207 complement(4621117..4621245) 1 NC_004431.1 hypothetical protein 4621245 1040207 c4860 Escherichia coli CFT073 hypothetical protein NP_756714.1 4621117 R 199310 CDS NP_756715.2 161486040 1040205 4621348..4622331 1 NC_004431.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4622331 kdgT 1040205 kdgT Escherichia coli CFT073 2-keto-3-deoxygluconate permease NP_756715.2 4621348 D 199310 CDS NP_756716.2 161486039 1040203 4622480..4623154 1 NC_004431.1 Escherichia coli K-12 ortholog: b3910; Escherichia coli O157:H7 ortholog: z5455; hypothetical protein 4623154 yiiM 1040203 yiiM Escherichia coli CFT073 hypothetical protein NP_756716.2 4622480 D 199310 CDS NP_756717.1 26250677 1040202 complement(4623260..4624633) 1 NC_004431.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4624633 cpxA 1040202 cpxA Escherichia coli CFT073 two-component sensor protein NP_756717.1 4623260 R 199310 CDS NP_756718.1 26250678 1040201 complement(4624630..4625328) 1 NC_004431.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4625328 cpxR 1040201 cpxR Escherichia coli CFT073 DNA-binding transcriptional regulator CpxR NP_756718.1 4624630 R 199310 CDS NP_756719.2 161486038 1040200 4625478..4625978 1 NC_004431.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4625978 cpxP 1040200 cpxP Escherichia coli CFT073 periplasmic repressor CpxP NP_756719.2 4625478 D 199310 CDS NP_756720.2 161486037 1040197 4626127..4627029 1 NC_004431.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4627029 fieF 1040197 fieF Escherichia coli CFT073 ferrous iron efflux protein F NP_756720.2 4626127 D 199310 CDS NP_756721.1 26250681 1040196 4627114..4628172 1 NC_004431.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4628172 pfkA 1040196 pfkA Escherichia coli CFT073 6-phosphofructokinase NP_756721.1 4627114 D 199310 CDS NP_756722.1 26250682 1040194 4628431..4628568 1 NC_004431.1 hypothetical protein 4628568 1040194 c4868 Escherichia coli CFT073 hypothetical protein NP_756722.1 4628431 D 199310 CDS NP_756723.1 26250683 1040192 4628492..4629481 1 NC_004431.1 Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462; sulfate transporter subunit 4629481 sbp 1040192 sbp Escherichia coli CFT073 sulfate transporter subunit NP_756723.1 4628492 D 199310 CDS NP_756724.1 26250684 1040191 4629396..4630343 1 NC_004431.1 Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463; CDP-diacylglycerol pyrophosphatase 4630343 cdh 1040191 cdh Escherichia coli CFT073 CDP-diacylglycerol pyrophosphatase NP_756724.1 4629396 D 199310 CDS NP_756725.1 26250685 1040189 complement(4630398..4631165) 1 NC_004431.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4631165 tpiA 1040189 tpiA Escherichia coli CFT073 triosephosphate isomerase NP_756725.1 4630398 R 199310 CDS NP_756726.1 26250686 1040188 complement(4631273..4631872) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3920; Escherichia coli O157:H7 ortholog: z5465; hypothetical protein 4631872 yiiQ 1040188 yiiQ Escherichia coli CFT073 hypothetical protein NP_756726.1 4631273 R 199310 CDS NP_756727.1 26250687 1040185 4631973..4632413 1 NC_004431.1 Escherichia coli K-12 ortholog: b3921; Escherichia coli O157:H7 ortholog: z5466; hypothetical protein 4632413 yiiR 1040185 yiiR Escherichia coli CFT073 hypothetical protein NP_756727.1 4631973 D 199310 CDS NP_756728.1 26250688 1040183 4632625..4632924 1 NC_004431.1 Escherichia coli K-12 ortholog: b3922; Escherichia coli O157:H7 ortholog: z5467; hypothetical protein 4632924 yiiS 1040183 yiiS Escherichia coli CFT073 hypothetical protein NP_756728.1 4632625 D 199310 CDS NP_756729.1 26250689 1040181 4632951..4633379 1 NC_004431.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4633379 yiiT 1040181 yiiT Escherichia coli CFT073 universal stress protein UspD NP_756729.1 4632951 D 199310 CDS NP_756730.1 26250690 1040178 complement(4633384..4634130) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3924; Escherichia coli O157:H7 ortholog: z5469; ferredoxin-NADP reductase 4634130 fpr 1040178 fpr Escherichia coli CFT073 ferredoxin-NADP reductase NP_756730.1 4633384 R 199310 CDS NP_756731.1 26250691 1040175 complement(4634227..4635237) 1 NC_004431.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4635237 glpX 1040175 glpX Escherichia coli CFT073 fructose 1,6-bisphosphatase II NP_756731.1 4634227 R 199310 CDS NP_756732.1 26250692 1040170 complement(4635408..4637021) 1 NC_004431.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4637021 glpK 1040170 glpK Escherichia coli CFT073 glycerol kinase NP_756732.1 4635408 R 199310 CDS NP_756733.1 26250693 1040169 complement(4636939..4637784) 1 NC_004431.1 Aquaglyceroporin; Escherichia coli K-12 ortholog: b3927; Escherichia coli O157:H7 ortholog: z5472; glycerol uptake facilitator protein 4637784 glpF 1040169 glpF Escherichia coli CFT073 glycerol uptake facilitator protein NP_756733.1 4636939 R 199310 CDS NP_756734.1 26250694 1040166 4638191..4638454 1 NC_004431.1 Escherichia coli K-12 ortholog: b3928; Escherichia coli O157:H7 ortholog: z5473; hypothetical protein 4638454 yiiU 1040166 yiiU Escherichia coli CFT073 hypothetical protein NP_756734.1 4638191 D 199310 CDS NP_756735.1 26250695 1040164 complement(4638539..4639024) 1 NC_004431.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4639024 menG 1040164 menG Escherichia coli CFT073 ribonuclease activity regulator protein RraA NP_756735.1 4638539 R 199310 CDS NP_756736.1 26250696 1040160 4638596..4639102 1 NC_004431.1 hypothetical protein 4639102 1040160 c4882 Escherichia coli CFT073 hypothetical protein NP_756736.1 4638596 D 199310 CDS NP_756737.1 26250697 1040156 complement(4639117..4640055) 1 NC_004431.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4640055 menA 1040156 menA Escherichia coli CFT073 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP_756737.1 4639117 R 199310 CDS NP_756738.1 26250698 1040155 complement(4640110..4641441) 1 NC_004431.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4641441 hslU 1040155 hslU Escherichia coli CFT073 ATP-dependent protease ATP-binding subunit HslU NP_756738.1 4640110 R 199310 CDS NP_756739.1 26250699 1040153 complement(4641451..4641981) 1 NC_004431.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4641981 hslV 1040153 hslV Escherichia coli CFT073 ATP-dependent protease peptidase subunit NP_756739.1 4641451 R 199310 CDS NP_756740.1 26250700 1040152 complement(4642074..4643033) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3933; Escherichia coli O157:H7 ortholog: z5480; essential cell division protein FtsN 4643033 ftsN 1040152 ftsN Escherichia coli CFT073 essential cell division protein FtsN NP_756740.1 4642074 R 199310 CDS NP_756741.1 26250701 1040151 complement(4643125..4644150) 1 NC_004431.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4644150 cytR 1040151 cytR Escherichia coli CFT073 DNA-binding transcriptional regulator CytR NP_756741.1 4643125 R 199310 CDS NP_756742.1 26250702 1040145 complement(4644306..4646576) 1 NC_004431.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4646576 priA 1040145 priA Escherichia coli CFT073 primosome assembly protein PriA NP_756742.1 4644306 R 199310 CDS NP_756743.1 26250703 1040141 complement(4646689..4646829) 1 NC_004431.1 hypothetical protein 4646829 1040141 c4889 Escherichia coli CFT073 hypothetical protein NP_756743.1 4646689 R 199310 CDS NP_756744.1 26250704 1040139 complement(4646980..4647588) 1 NC_004431.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 4647588 yiiX 1040139 yiiX Escherichia coli CFT073 peptidoglycan peptidase NP_756744.1 4646980 R 199310 CDS NP_756745.1 26250705 1040138 complement(4647648..4648103) 1 NC_004431.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4648103 metJ 1040138 metJ Escherichia coli CFT073 transcriptional repressor protein MetJ NP_756745.1 4647648 R 199310 CDS NP_756746.1 26250706 1040136 4648128..4649402 1 NC_004431.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4649402 metB 1040136 metB Escherichia coli CFT073 cystathionine gamma-synthase NP_756746.1 4648128 D 199310 CDS NP_756747.1 26250707 1040134 4649405..4651837 1 NC_004431.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4651837 metL 1040134 metL Escherichia coli CFT073 bifunctional aspartate kinase II/homoserine dehydrogenase II NP_756747.1 4649405 D 199310 CDS NP_756748.1 26250708 1040130 complement(4652055..4652915) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512; nucleoside-specific channel-forming protein tsx 4652915 1040130 c4894 Escherichia coli CFT073 nucleoside-specific channel-forming protein tsx NP_756748.1 4652055 R 199310 CDS NP_756749.1 26250709 1040128 complement(4652992..4654617) 1 NC_004431.1 Residues 10 to 537 of 541 are 64.65 pct identical to residues 5 to 513 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; hypothetical protein 4654617 1040128 c4895 Escherichia coli CFT073 hypothetical protein NP_756749.1 4652992 R 199310 CDS NP_756750.1 26250710 1040123 complement(4654652..4656205) 1 NC_004431.1 Residues 3 to 517 of 517 are 58.95 pct identical to residues 7 to 523 of 523 from GenPept.129 : >gb|AAL18997.1| (AE008694) 5'-nucleotidase [Salmonella typhimurium LT2]; hypothetical protein 4656205 1040123 c4896 Escherichia coli CFT073 hypothetical protein NP_756750.1 4654652 R 199310 CDS NP_756751.1 26250711 1040119 complement(4656435..4657559) 1 NC_004431.1 Residues 1 to 367 of 374 are 61.68 pct identical to residues 1 to 368 of 374 from GenPept.129 : >gb|AAL22943.1| (AE008891) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 4657559 1040119 c4897 Escherichia coli CFT073 hypothetical protein NP_756751.1 4656435 R 199310 CDS NP_756752.1 26250712 1040116 4657686..4659245 1 NC_004431.1 Residues 3 to 519 of 519 are 91.87 pct identical to residues 1 to 517 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; hypothetical protein 4659245 1040116 c4898 Escherichia coli CFT073 hypothetical protein NP_756752.1 4657686 D 199310 CDS NP_756753.1 26250713 1040113 4659627..4660517 1 NC_004431.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4660517 metF 1040113 metF Escherichia coli CFT073 5,10-methylenetetrahydrofolate reductase NP_756753.1 4659627 D 199310 CDS NP_756754.1 26250714 1040112 4660807..4663026 1 NC_004431.1 Escherichia coli K-12 ortholog: b3942; Escherichia coli O157:H7 ortholog: z5497; peroxidase/catalase HPI 4663026 katG 1040112 katG Escherichia coli CFT073 peroxidase/catalase HPI NP_756754.1 4660807 D 199310 CDS NP_756755.1 26250715 1040110 4663054..4664025 1 NC_004431.1 Escherichia coli K-12 ortholog: b3943; Escherichia coli O157:H7 ortholog: z5498; transport protein YijE 4664025 yijE 1040110 yijE Escherichia coli CFT073 transport protein YijE NP_756755.1 4663054 D 199310 CDS NP_756756.1 26250716 1040109 complement(4664052..4664669) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3944; Escherichia coli O157:H7 ortholog: z5499; hypothetical protein 4664669 yijF 1040109 yijF Escherichia coli CFT073 hypothetical protein NP_756756.1 4664052 R 199310 CDS NP_756757.1 26250717 1040108 complement(4664569..4664763) 1 NC_004431.1 hypothetical protein 4664763 1040108 c4903 Escherichia coli CFT073 hypothetical protein NP_756757.1 4664569 R 199310 CDS NP_756758.2 161486036 1040105 complement(4664945..4666048) 1 NC_004431.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4666048 gldA 1040105 gldA Escherichia coli CFT073 glycerol dehydrogenase NP_756758.2 4664945 R 199310 CDS NP_756759.1 26250719 1040104 complement(4666059..4666721) 1 NC_004431.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4666721 talC 1040104 talC Escherichia coli CFT073 fructose-6-phosphate aldolase NP_756759.1 4666059 R 199310 CDS NP_756760.1 26250720 1040102 complement(4666733..4669234) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3947; Escherichia coli O157:H7 ortholog: z5502; phosphoenolpyruvate-protein phosphotransferase ptsA 4669234 ptsA 1040102 ptsA Escherichia coli CFT073 phosphoenolpyruvate-protein phosphotransferase ptsA NP_756760.1 4666733 R 199310 CDS NP_756761.1 26250721 1040100 4669543..4670622 1 NC_004431.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4670622 frwC 1040100 frwC Escherichia coli CFT073 fructose-like permease EIIC subunit 2 NP_756761.1 4669543 D 199310 CDS NP_756762.1 26250722 1040099 4670637..4670957 1 NC_004431.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4670957 frwB 1040099 frwB Escherichia coli CFT073 PTS system fructose-like transporter subunit EIIB NP_756762.1 4670637 D 199310 CDS NP_756763.1 26250723 1040097 complement(4670670..4670996) 1 NC_004431.1 hypothetical protein 4670996 1040097 c4909 Escherichia coli CFT073 hypothetical protein NP_756763.1 4670670 R 199310 CDS NP_756764.1 26250724 1040094 4671008..4673305 1 NC_004431.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4673305 pflD 1040094 pflD Escherichia coli CFT073 formate acetyltransferase 2 NP_756764.1 4671008 D 199310 CDS NP_756765.1 26250725 1040091 4673271..4674149 1 NC_004431.1 Escherichia coli K-12 ortholog: b3952; Escherichia coli O157:H7 ortholog: z5508; pyruvate formate lyase II activase 4674149 pflC 1040091 pflC Escherichia coli CFT073 pyruvate formate lyase II activase NP_756765.1 4673271 D 199310 CDS NP_756766.1 26250726 1040090 4674151..4674492 1 NC_004431.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4674492 frwD 1040090 frwD Escherichia coli CFT073 fructose-like phosphotransferase EIIB subunit 3 NP_756766.1 4674151 D 199310 CDS NP_756767.1 26250727 1040083 complement(4674479..4675330) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3954; Escherichia coli O157:H7 ortholog: z5512; transcriptional regulator YijO 4675330 yijO 1040083 yijO Escherichia coli CFT073 transcriptional regulator YijO NP_756767.1 4674479 R 199310 CDS NP_756768.2 161486035 1040081 complement(4675556..4677289) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3955; Escherichia coli O157:H7 ortholog: z5513; hypothetical protein 4677289 yijP 1040081 yijP Escherichia coli CFT073 hypothetical protein NP_756768.2 4675556 R 199310 CDS NP_756769.1 26250729 1040079 complement(4677472..4680123) 1 NC_004431.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4680123 ppc 1040079 ppc Escherichia coli CFT073 phosphoenolpyruvate carboxylase NP_756769.1 4677472 R 199310 CDS NP_756770.1 26250730 1040075 complement(4680425..4681615) 1 NC_004431.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4681615 argE 1040075 argE Escherichia coli CFT073 acetylornithine deacetylase NP_756770.1 4680425 R 199310 CDS NP_756771.1 26250731 1040073 4681730..4682734 1 NC_004431.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4682734 argC 1040073 argC Escherichia coli CFT073 N-acetyl-gamma-glutamyl-phosphate reductase NP_756771.1 4681730 D 199310 CDS NP_756772.2 161486034 1040069 4682745..4683518 1 NC_004431.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4683518 argB 1040069 argB Escherichia coli CFT073 acetylglutamate kinase NP_756772.2 4682745 D 199310 CDS NP_756773.1 26250733 1040068 4683579..4684952 1 NC_004431.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4684952 argH 1040068 argH Escherichia coli CFT073 argininosuccinate lyase NP_756773.1 4683579 D 199310 CDS NP_756774.1 26250734 1040066 4685450..4686664 1 NC_004431.1 Escherichia coli K-12 ortholog: b1581; starvation sensing protein rspA 4686664 1040066 c4920 Escherichia coli CFT073 starvation sensing protein rspA NP_756774.1 4685450 D 199310 CDS NP_756775.1 26250735 1040060 4686731..4688014 1 NC_004431.1 Escherichia coli K-12 ortholog: b4356; Escherichia coli O157:H7 ortholog: z5956; transport protein YjjL 4688014 yjiZ 1040060 yjiZ Escherichia coli CFT073 transport protein YjjL NP_756775.1 4686731 D 199310 CDS NP_756776.2 161486033 1040058 4688266..4689183 1 NC_004431.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4689183 oxyR 1040058 oxyR Escherichia coli CFT073 DNA-binding transcriptional regulator OxyR NP_756776.2 4688266 D 199310 CDS NP_756777.1 26250737 1040055 complement(4689166..4690566) 1 NC_004431.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4690566 udhA 1040055 udhA Escherichia coli CFT073 soluble pyridine nucleotide transhydrogenase NP_756777.1 4689166 R 199310 CDS NP_756778.1 26250738 1040050 4690896..4692062 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5522; hippuricase 4692062 1040050 c4924 Escherichia coli CFT073 hippuricase NP_756778.1 4690896 D 199310 CDS NP_756779.1 26250739 1040046 4692105..4693421 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5523; citrate permease 4693421 1040046 c4925 Escherichia coli CFT073 citrate permease NP_756779.1 4692105 D 199310 CDS NP_756780.1 26250740 1040045 4693471..4694175 1 NC_004431.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4694175 yijC 1040045 yijC Escherichia coli CFT073 DNA-binding transcriptional repressor FabR NP_756780.1 4693471 D 199310 CDS NP_756781.1 26250741 1040034 4694175..4694534 1 NC_004431.1 Escherichia coli K-12 ortholog: b3964; Escherichia coli O157:H7 ortholog: z5525; hypothetical protein 4694534 yijD 1040034 yijD Escherichia coli CFT073 hypothetical protein NP_756781.1 4694175 D 199310 CDS NP_756782.1 26250742 1040031 complement(4694574..4695674) 1 NC_004431.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4695674 trmA 1040031 trmA Escherichia coli CFT073 tRNA (uracil-5-)-methyltransferase NP_756782.1 4694574 R 199310 CDS NP_756783.2 229106362 1040029 4696043..4697887 1 NC_004431.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4697887 btuB 1040029 btuB Escherichia coli CFT073 vitamin B12/cobalamin outer membrane transporter NP_756783.2 4696043 D 199310 CDS NP_756784.1 26250744 1040024 4697832..4698689 1 NC_004431.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4698689 murI 1040024 murI Escherichia coli CFT073 glutamate racemase NP_756784.1 4697832 D 199310 CDS NP_756785.1 26250745 1039893 4704305..4705333 1 NC_004431.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4705333 murB 1039893 murB Escherichia coli CFT073 UDP-N-acetylenolpyruvoylglucosamine reductase NP_756785.1 4704305 D 199310 CDS NP_756786.1 26250746 1039892 4705330..4706295 1 NC_004431.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4706295 birA 1039892 birA Escherichia coli CFT073 biotin--protein ligase NP_756786.1 4705330 D 199310 CDS NP_756787.1 26250747 1039891 complement(4706324..4707295) 1 NC_004431.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4707295 coaA 1039891 coaA Escherichia coli CFT073 pantothenate kinase NP_756787.1 4706324 R 199310 CDS NP_756788.1 26250748 1039890 complement(4707331..4707492) 1 NC_004431.1 Residues 1 to 53 of 53 are 96.22 pct identical to residues 1 to 53 of 53 from SwissProt.40 : >sp|P15045|YZRS_ECOLI VERY HYPOTHETICAL 6.2 KD PROTEIN IN RTS 5'REGION; hypothetical protein 4707492 1039890 c4934 Escherichia coli CFT073 hypothetical protein NP_756788.1 4707331 R 199310 CDS NP_756789.1 26250749 1039881 4708192..4709376 1 NC_004431.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4709376 tuf 1039881 tuf Escherichia coli CFT073 elongation factor Tu NP_756789.1 4708192 D 199310 CDS NP_756790.1 26250750 1039880 4709606..4709989 1 NC_004431.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4709989 secE 1039880 secE Escherichia coli CFT073 preprotein translocase subunit SecE NP_756790.1 4709606 D 199310 CDS NP_756791.1 26250751 1039879 4709991..4710536 1 NC_004431.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4710536 nusG 1039879 nusG Escherichia coli CFT073 transcription antitermination protein NusG NP_756791.1 4709991 D 199310 CDS NP_756792.1 26250752 1039877 complement(4710641..4711642) 1 NC_004431.1 hypothetical protein 4711642 1039877 c4938 Escherichia coli CFT073 hypothetical protein NP_756792.1 4710641 R 199310 CDS NP_756793.1 26250753 1039875 4710695..4711123 1 NC_004431.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4711123 rplK 1039875 rplK Escherichia coli CFT073 50S ribosomal protein L11 NP_756793.1 4710695 D 199310 CDS NP_756794.1 26250754 1039874 4711127..4711831 1 NC_004431.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4711831 rplA 1039874 rplA Escherichia coli CFT073 50S ribosomal protein L1 NP_756794.1 4711127 D 199310 CDS NP_756795.1 26250755 1039873 4712123..4712620 1 NC_004431.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4712620 rplJ 1039873 rplJ Escherichia coli CFT073 50S ribosomal protein L10 NP_756795.1 4712123 D 199310 CDS NP_756796.1 26250756 1039872 complement(4712672..4713178) 1 NC_004431.1 hypothetical protein 4713178 1039872 c4942 Escherichia coli CFT073 hypothetical protein NP_756796.1 4712672 R 199310 CDS NP_756797.1 26250757 1039871 4712687..4713052 1 NC_004431.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4713052 rplL 1039871 rplL Escherichia coli CFT073 50S ribosomal protein L7/L12 NP_756797.1 4712687 D 199310 CDS NP_756798.1 26250758 1039870 4713339..4717400 1 NC_004431.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4717400 rpoB 1039870 rpoB Escherichia coli CFT073 DNA-directed RNA polymerase subunit beta NP_756798.1 4713339 D 199310 CDS NP_756799.1 26250759 1039869 4717477..4721700 1 NC_004431.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4721700 rpoC 1039869 rpoC Escherichia coli CFT073 DNA-directed RNA polymerase subunit beta' NP_756799.1 4717477 D 199310 CDS NP_756800.1 26250760 1039868 complement(4721942..4723075) 1 NC_004431.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4723075 thiH 1039868 thiH Escherichia coli CFT073 thiamine biosynthesis protein ThiH NP_756800.1 4721942 R 199310 CDS NP_756801.2 161486032 1039866 complement(4723072..4723842) 1 NC_004431.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4723842 thiG 1039866 thiG Escherichia coli CFT073 thiazole synthase NP_756801.2 4723072 R 199310 CDS NP_756802.1 26250762 1039865 complement(4723844..4724044) 1 NC_004431.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4724044 thiS 1039865 thiS Escherichia coli CFT073 sulfur carrier protein ThiS NP_756802.1 4723844 R 199310 CDS NP_756803.3 347357878 1039863 complement(4724028..4724798) 1 NC_004431.1 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate; adenylyltransferase 4724798 thiF 1039863 thiF Escherichia coli CFT073 adenylyltransferase NP_756803.3 4724028 R 199310 CDS NP_756804.1 26250764 1039862 complement(4724776..4725414) 1 NC_004431.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4725414 thiE 1039862 thiE Escherichia coli CFT073 thiamine-phosphate pyrophosphorylase NP_756804.1 4724776 R 199310 CDS NP_756805.1 26250765 1039860 complement(4725411..4727318) 1 NC_004431.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4727318 thiC 1039860 thiC Escherichia coli CFT073 thiamine biosynthesis protein ThiC NP_756805.1 4725411 R 199310 CDS NP_756806.1 26250766 1039858 complement(4727539..4728015) 1 NC_004431.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4728015 yjaE 1039858 yjaE Escherichia coli CFT073 anti-RNA polymerase sigma 70 factor NP_756806.1 4727539 R 199310 CDS NP_756807.1 26250767 1039857 4728110..4728883 1 NC_004431.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4728883 nudC 1039857 nudC Escherichia coli CFT073 NADH pyrophosphatase NP_756807.1 4728110 D 199310 CDS NP_756808.1 26250768 1039856 4728923..4729987 1 NC_004431.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4729987 hemE 1039856 hemE Escherichia coli CFT073 uroporphyrinogen decarboxylase NP_756808.1 4728923 D 199310 CDS NP_756809.1 26250769 1039855 4729997..4730668 1 NC_004431.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4730668 nfi 1039855 nfi Escherichia coli CFT073 endonuclease V NP_756809.1 4729997 D 199310 CDS NP_756810.1 26250770 1039854 4730711..4731301 1 NC_004431.1 Escherichia coli K-12 ortholog: b3999; Escherichia coli O157:H7 ortholog: z5575; hypothetical protein 4731301 yjaG 1039854 yjaG Escherichia coli CFT073 hypothetical protein NP_756810.1 4730711 D 199310 CDS NP_756811.1 26250771 1039853 4731488..4731760 1 NC_004431.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4731760 hupA 1039853 hupA Escherichia coli CFT073 transcriptional regulator HU subunit alpha NP_756811.1 4731488 D 199310 CDS NP_756812.1 26250772 1039851 4731767..4732468 1 NC_004431.1 Escherichia coli K-12 ortholog: b4001; Escherichia coli O157:H7 ortholog: z5577; hypothetical protein 4732468 yjaH 1039851 yjaH Escherichia coli CFT073 hypothetical protein NP_756812.1 4731767 D 199310 CDS NP_756813.3 347357877 1039849 complement(4732470..4733030) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4002; Escherichia coli O157:H7 ortholog: z5578; zinc resistance protein 4733030 zraP 1039849 zraP Escherichia coli CFT073 zinc resistance protein NP_756813.3 4732470 R 199310 CDS NP_756814.1 26250774 1039848 complement(4732892..4733020) 1 NC_004431.1 hypothetical protein 4733020 1039848 c4960 Escherichia coli CFT073 hypothetical protein NP_756814.1 4732892 R 199310 CDS NP_756815.1 26250775 1039846 4733127..4734503 1 NC_004431.1 Escherichia coli K-12 ortholog: b4003; Escherichia coli O157:H7 ortholog: z5579; sensor protein ZraS 4734503 hydH 1039846 hydH Escherichia coli CFT073 sensor protein ZraS NP_756815.1 4733127 D 199310 CDS NP_756816.1 26250776 1039844 4734500..4735825 1 NC_004431.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4735825 hydG 1039844 hydG Escherichia coli CFT073 transcriptional regulatory protein ZraR NP_756816.1 4734500 D 199310 CDS NP_756817.1 26250777 1039843 complement(4735822..4737111) 1 NC_004431.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4737111 purD 1039843 purD Escherichia coli CFT073 phosphoribosylamine--glycine ligase NP_756817.1 4735822 R 199310 CDS NP_756818.1 26250778 1039842 complement(4737123..4738712) 1 NC_004431.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4738712 purH 1039842 purH Escherichia coli CFT073 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_756818.1 4737123 R 199310 CDS NP_756819.1 26250779 1039841 4738830..4738952 1 NC_004431.1 hypothetical protein 4738952 1039841 c4965 Escherichia coli CFT073 hypothetical protein NP_756819.1 4738830 D 199310 CDS NP_756820.1 26250780 1039833 4744384..4744803 1 NC_004431.1 Escherichia coli K-12 ortholog: b4011; hypothetical protein 4744803 yjaA 1039833 yjaA Escherichia coli CFT073 hypothetical protein NP_756820.1 4744384 D 199310 CDS NP_756821.1 26250781 1039831 complement(4744867..4745310) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4012; Escherichia coli O157:H7 ortholog: z5598; hypothetical protein 4745310 yjaB 1039831 yjaB Escherichia coli CFT073 hypothetical protein NP_756821.1 4744867 R 199310 CDS NP_756822.1 26250782 1039773 4745467..4746396 1 NC_004431.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4746396 metA 1039773 metA Escherichia coli CFT073 homoserine O-succinyltransferase NP_756822.1 4745467 D 199310 CDS NP_756823.1 26250783 1039772 4746647..4748266 1 NC_004431.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4748266 aceB 1039772 aceB Escherichia coli CFT073 malate synthase NP_756823.1 4746647 D 199310 CDS NP_756824.1 26250784 1039771 4748281..4749600 1 NC_004431.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 4749600 aceA 1039771 aceA Escherichia coli CFT073 isocitrate lyase NP_756824.1 4748281 D 199310 CDS NP_756825.1 26250785 1039770 4749615..4749761 1 NC_004431.1 Residues 3 to 46 of 48 are 61.70 pct identical to residues 21 to 67 of 103 from GenPept.129 : >gb|AAB18079.1| (U73857) hypothetical protein [Escherichia coli]; hypothetical protein 4749761 1039770 c4973 Escherichia coli CFT073 hypothetical protein NP_756825.1 4749615 D 199310 CDS NP_756826.1 26250786 1039769 4749816..4751540 1 NC_004431.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4751540 aceK 1039769 aceK Escherichia coli CFT073 bifunctional isocitrate dehydrogenase kinase/phosphatase protein NP_756826.1 4749816 D 199310 CDS NP_756827.2 161486029 1039766 complement(4751557..4752381) 1 NC_004431.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR 4752381 iclR 1039766 iclR Escherichia coli CFT073 transcriptional repressor IclR NP_756827.2 4751557 R 199310 CDS NP_756828.1 26250788 1039765 4752581..4756264 1 NC_004431.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4756264 metH 1039765 metH Escherichia coli CFT073 B12-dependent methionine synthase NP_756828.1 4752581 D 199310 CDS NP_756829.1 26250789 1039763 4756318..4756644 1 NC_004431.1 hypothetical protein 4756644 1039763 c4977 Escherichia coli CFT073 hypothetical protein NP_756829.1 4756318 D 199310 CDS NP_756830.1 26250790 1039762 4756687..4757136 1 NC_004431.1 Residues 6 to 145 of 149 are 32.85 pct identical to residues 4 to 137 of 138 from GenPept.129 : >emb|CAC92271.1| (AJ414155) membrane protein [Yersinia pestis]; hypothetical protein 4757136 1039762 c4978 Escherichia coli CFT073 hypothetical protein NP_756830.1 4756687 D 199310 CDS NP_756831.1 26250791 1039761 4757307..4758938 1 NC_004431.1 Escherichia coli K-12 ortholog: b4020; Escherichia coli O157:H7 ortholog: z5611; hypothetical protein 4758938 yjbB 1039761 yjbB Escherichia coli CFT073 hypothetical protein NP_756831.1 4757307 D 199310 CDS NP_756832.1 26250792 1039759 complement(4759028..4759717) 1 NC_004431.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4759717 pepE 1039759 pepE Escherichia coli CFT073 peptidase E NP_756832.1 4759028 R 199310 CDS NP_756833.1 26250793 1039757 complement(4760099..4761328) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z5613; oxidoreductase 4761328 1039757 c4981 Escherichia coli CFT073 oxidoreductase NP_756833.1 4760099 R 199310 CDS NP_756834.1 26250794 1039753 complement(4761380..4762234) 1 NC_004431.1 EIID-Man; Escherichia coli K-12 ortholog: b1819; Escherichia coli O157:H7 ortholog: z5614; PTS system, mannose-specific IID component 4762234 1039753 c4982 Escherichia coli CFT073 PTS system, mannose-specific IID component NP_756834.1 4761380 R 199310 CDS NP_756835.1 26250795 1039752 complement(4762215..4763012) 1 NC_004431.1 EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z5615; PTS system, mannose-specific IIC component 4763012 1039752 c4983 Escherichia coli CFT073 PTS system, mannose-specific IIC component NP_756835.1 4762215 R 199310 CDS NP_756836.1 26250796 1039741 complement(4763078..4763572) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5616; sorbose PTS component 4763572 1039741 c4984 Escherichia coli CFT073 sorbose PTS component NP_756836.1 4763078 R 199310 CDS NP_756837.1 26250797 1039738 complement(4763572..4763979) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5617; sorbose PTS component 4763979 1039738 c4985 Escherichia coli CFT073 sorbose PTS component NP_756837.1 4763572 R 199310 CDS NP_756838.1 26250798 1039729 complement(4763989..4764795) 1 NC_004431.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4764795 1039729 c4986 Escherichia coli CFT073 sorbitol-6-phosphate 2-dehydrogenase NP_756838.1 4763989 R 199310 CDS NP_756839.1 26250799 1039719 complement(4764865..4765896) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5619; transcriptional regulator of sorbose uptake and utilization genes 4765896 1039719 c4987 Escherichia coli CFT073 transcriptional regulator of sorbose uptake and utilization genes NP_756839.1 4764865 R 199310 CDS NP_756840.1 26250800 1039712 4766160..4767032 1 NC_004431.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4767032 yjbC 1039712 yjbC Escherichia coli CFT073 23S rRNA pseudouridine synthase F NP_756840.1 4766160 D 199310 CDS NP_756841.1 26250801 1039707 complement(4767033..4767305) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4023; Escherichia coli O157:H7 ortholog: z5621; hypothetical protein 4767305 yjbD 1039707 yjbD Escherichia coli CFT073 hypothetical protein NP_756841.1 4767033 R 199310 CDS NP_756842.1 26250802 1039699 complement(4767558..4768907) 1 NC_004431.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 4768907 lysC 1039699 lysC Escherichia coli CFT073 aspartate kinase NP_756842.1 4767558 R 199310 CDS NP_756843.2 161486028 1039694 4769432..4771081 1 NC_004431.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4771081 pgi 1039694 pgi Escherichia coli CFT073 glucose-6-phosphate isomerase NP_756843.2 4769432 D 199310 CDS YP_004853836.1 347357920 1039692 complement(4771477..4771971) 1 NC_004431.1 hypothetical protein 4771971 1039692 c4992 Escherichia coli CFT073 hypothetical protein YP_004853836.1 4771477 R 199310 CDS YP_004853837.1 347357921 1039620 complement(4771560..4771889) 1 NC_004431.1 hypothetical protein 4771889 1039620 c4993 Escherichia coli CFT073 hypothetical protein YP_004853837.1 4771560 R 199310 CDS NP_756846.1 26250806 1039615 4771579..4771821 1 NC_004431.1 Escherichia coli K-12 ortholog: b4026; Escherichia coli O157:H7 ortholog: z5624; hypothetical protein 4771821 yjbE 1039615 yjbE Escherichia coli CFT073 hypothetical protein NP_756846.1 4771579 D 199310 CDS NP_756847.1 26250807 1039614 4771978..4772646 1 NC_004431.1 Escherichia coli K-12 ortholog: b4027; Escherichia coli O157:H7 ortholog: z5625; lipoprotein yjbF 4772646 yjbF 1039614 yjbF Escherichia coli CFT073 lipoprotein yjbF NP_756847.1 4771978 D 199310 CDS NP_756848.1 26250808 1039612 4772643..4773380 1 NC_004431.1 Escherichia coli K-12 ortholog: b4028; Escherichia coli O157:H7 ortholog: z5626; hypothetical protein 4773380 yjbG 1039612 yjbG Escherichia coli CFT073 hypothetical protein NP_756848.1 4772643 D 199310 CDS NP_756849.1 26250809 1039611 4773380..4775476 1 NC_004431.1 Escherichia coli K-12 ortholog: b4029; Escherichia coli O157:H7 ortholog: z5627; lipoprotein yjbH 4775476 yjbH 1039611 yjbH Escherichia coli CFT073 lipoprotein yjbH NP_756849.1 4773380 D 199310 CDS NP_756850.1 26250810 1039610 4775480..4775641 1 NC_004431.1 hypothetical protein 4775641 1039610 c4998 Escherichia coli CFT073 hypothetical protein NP_756850.1 4775480 D 199310 CDS NP_756851.1 26250811 1039609 complement(4775523..4775801) 1 NC_004431.1 hypothetical protein 4775801 1039609 c4999 Escherichia coli CFT073 hypothetical protein NP_756851.1 4775523 R 199310 CDS NP_756852.1 26250812 1039606 complement(4775798..4775920) 1 NC_004431.1 hypothetical protein 4775920 1039606 c5000 Escherichia coli CFT073 hypothetical protein NP_756852.1 4775798 R 199310 CDS NP_756853.1 26250813 1039600 4776016..4776426 1 NC_004431.1 Escherichia coli K-12 ortholog: b4030; Escherichia coli O157:H7 ortholog: z5628; phosphate-starvation-inducible protein PsiE 4776426 yjbA 1039600 yjbA Escherichia coli CFT073 phosphate-starvation-inducible protein PsiE NP_756853.1 4776016 D 199310 CDS NP_756854.1 26250814 1039585 complement(4776520..4777410) 1 NC_004431.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4777410 malG 1039585 malG Escherichia coli CFT073 maltose transporter permease NP_756854.1 4776520 R 199310 CDS NP_756855.1 26250815 1039565 complement(4777425..4778984) 1 NC_004431.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4778984 malF 1039565 malF Escherichia coli CFT073 maltose transporter membrane protein NP_756855.1 4777425 R 199310 CDS NP_756856.1 26250816 1039564 complement(4779123..4780313) 1 NC_004431.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4780313 malE 1039564 malE Escherichia coli CFT073 maltose ABC transporter periplasmic protein NP_756856.1 4779123 R 199310 CDS NP_756857.1 26250817 1039562 4780588..4781793 1 NC_004431.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4781793 malK 1039562 malK Escherichia coli CFT073 maltose/maltodextrin transporter ATP-binding protein NP_756857.1 4780588 D 199310 CDS NP_756858.1 26250818 1039561 4781865..4783205 1 NC_004431.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4783205 lamB 1039561 lamB Escherichia coli CFT073 maltoporin NP_756858.1 4781865 D 199310 CDS NP_756859.1 26250819 1039555 4783428..4784357 1 NC_004431.1 Escherichia coli K-12 ortholog: b4037; Escherichia coli O157:H7 ortholog: z5635; maltose regulon periplasmic protein 4784357 malM 1039555 malM Escherichia coli CFT073 maltose regulon periplasmic protein NP_756859.1 4783428 D 199310 CDS NP_756860.1 26250820 1039552 4784370..4784522 1 NC_004431.1 hypothetical protein 4784522 1039552 c5008 Escherichia coli CFT073 hypothetical protein NP_756860.1 4784370 D 199310 CDS NP_756861.1 26250821 1039545 4784536..4785033 1 NC_004431.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4785033 ubiC 1039545 ubiC Escherichia coli CFT073 chorismate pyruvate lyase NP_756861.1 4784536 D 199310 CDS NP_756862.1 26250822 1039481 4785046..4785918 1 NC_004431.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4785918 ubiA 1039481 ubiA Escherichia coli CFT073 4-hydroxybenzoate octaprenyltransferase NP_756862.1 4785046 D 199310 CDS NP_756863.2 161486027 1039432 complement(4786073..4788496) 1 NC_004431.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4788496 plsB 1039432 plsB Escherichia coli CFT073 glycerol-3-phosphate acyltransferase NP_756863.2 4786073 R 199310 CDS NP_756864.1 26250824 1039399 complement(4788342..4788704) 1 NC_004431.1 hypothetical protein 4788704 1039399 c5012 Escherichia coli CFT073 hypothetical protein NP_756864.1 4788342 R 199310 CDS NP_756865.1 26250825 1039398 4788667..4789035 1 NC_004431.1 Escherichia coli K-12 ortholog: b4042; Escherichia coli O157:H7 ortholog: z5641; diacylglycerol kinase 4789035 dgkA 1039398 dgkA Escherichia coli CFT073 diacylglycerol kinase NP_756865.1 4788667 D 199310 CDS NP_756866.1 26250826 1039346 4789145..4789753 1 NC_004431.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4789753 lexA 1039346 lexA Escherichia coli CFT073 LexA repressor NP_756866.1 4789145 D 199310 CDS NP_756867.2 161486026 1039344 4789826..4791151 1 NC_004431.1 Escherichia coli K-12 ortholog: b4044; Escherichia coli O157:H7 ortholog: z5643; DNA-damage-inducible SOS response protein 4791151 dinF 1039344 dinF Escherichia coli CFT073 DNA-damage-inducible SOS response protein NP_756867.2 4789826 D 199310 CDS NP_756868.1 26250828 1039343 4791261..4791476 1 NC_004431.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4791476 yjbJ 1039343 yjbJ Escherichia coli CFT073 stress-response protein NP_756868.1 4791261 D 199310 CDS NP_756869.2 161486025 1039338 complement(4791518..4792033) 1 NC_004431.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4792033 yjbK 1039338 yjbK Escherichia coli CFT073 zinc uptake transcriptional repressor NP_756869.2 4791518 R 199310 CDS NP_756870.1 26250830 1039337 4792189..4793184 1 NC_004431.1 Escherichia coli K-12 ortholog: b4049; Escherichia coli O157:H7 ortholog: z5647; tRNA-dihydrouridine synthase A 4793184 yjbN 1039337 yjbN Escherichia coli CFT073 tRNA-dihydrouridine synthase A NP_756870.1 4792189 D 199310 CDS NP_756871.2 161486024 1039331 4793318..4793560 1 NC_004431.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4793560 pspG 1039331 pspG Escherichia coli CFT073 phage shock protein G NP_756871.2 4793318 D 199310 CDS NP_756872.1 26250832 1039326 complement(4793725..4794708) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4051; Escherichia coli O157:H7 ortholog: z5649; quinone oxidoreductase, NADPH-dependent 4794708 qor 1039326 qor Escherichia coli CFT073 quinone oxidoreductase, NADPH-dependent NP_756872.1 4793725 R 199310 CDS NP_756873.1 26250833 1039324 complement(4794814..4796979) 1 NC_004431.1 Residues 70 to 648 of 721 are 36.66 pct identical to residues 6 to 596 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, [Thermotoga maritima]; oxidoreductase 4796979 1039324 c5021 Escherichia coli CFT073 oxidoreductase NP_756873.1 4794814 R 199310 CDS NP_756874.1 26250834 1039322 complement(4796852..4798252) 1 NC_004431.1 Residues 18 to 448 of 466 are 40.90 pct identical to residues 24 to 452 of 453 from GenPept.129 : >emb|CAB72806.1| (AL139074) transmembrane transport protein [Campylobacter jejuni]; transmembrane transport protein 4798252 1039322 c5022 Escherichia coli CFT073 transmembrane transport protein NP_756874.1 4796852 R 199310 CDS NP_756875.1 26250835 1039320 complement(4798343..4799122) 1 NC_004431.1 Residues 14 to 256 of 259 are 43.20 pct identical to residues 13 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) dehydratase [Sinorhizobium meliloti]; crotonase 4799122 1039320 c5023 Escherichia coli CFT073 crotonase NP_756875.1 4798343 R 199310 CDS NP_756876.1 26250836 1039309 complement(4799115..4800686) 1 NC_004431.1 Residues 5 to 517 of 523 are 68.03 pct identical to residues 3 to 514 of 533 from GenPept.129 : >dbj|BAB50030.1| (AP003001) Acetyl-CoA:acetoacetyl-CoA transferase a subunit [Mesorhizobium loti]; propionate CoA-transferase 4800686 1039309 c5024 Escherichia coli CFT073 propionate CoA-transferase NP_756876.1 4799115 R 199310 CDS NP_756877.1 26250837 1039307 4800915..4801976 1 NC_004431.1 Residues 16 to 349 of 353 are 38.46 pct identical to residues 2 to 335 of 347 from GenPept.129 : >emb|CAC47885.1| (AL591793) TRANSCRIPTION REGULATOR PROTEIN [Sinorhizobium meliloti]; regulator 4801976 1039307 c5025 Escherichia coli CFT073 regulator NP_756877.1 4800915 D 199310 CDS NP_756878.1 26250838 1039305 4802013..4803464 1 NC_004431.1 unwinds double stranded DNA; replicative DNA helicase 4803464 dnaB 1039305 dnaB Escherichia coli CFT073 replicative DNA helicase NP_756878.1 4802013 D 199310 CDS NP_756879.1 26250839 1039300 complement(4803499..4804239) 1 NC_004431.1 hypothetical protein 4804239 1039300 c5027 Escherichia coli CFT073 hypothetical protein NP_756879.1 4803499 R 199310 CDS NP_756880.1 26250840 1039290 4804186..4805265 1 NC_004431.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4805265 alr 1039290 alr Escherichia coli CFT073 alanine racemase NP_756880.1 4804186 D 199310 CDS NP_756881.1 26250841 1039284 4805288..4805845 1 NC_004431.1 Residues 1 to 181 of 185 are 36.81 pct identical to residues 1 to 182 of 191 from GenPept.129 : >gb|AAG05346.1|AE004622_8 (AE004622) probable transporter [Pseudomonas aeruginosa]; transporter 4805845 1039284 c5029 Escherichia coli CFT073 transporter NP_756881.1 4805288 D 199310 CDS NP_756882.1 26250842 1039283 4805818..4806846 1 NC_004431.1 Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]; NadR-like protein 4806846 1039283 c5030 Escherichia coli CFT073 NadR-like protein NP_756882.1 4805818 D 199310 CDS NP_756883.2 161486023 1039275 4806928..4808121 1 NC_004431.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4808121 tyrB 1039275 tyrB Escherichia coli CFT073 aromatic amino acid aminotransferase NP_756883.2 4806928 D 199310 CDS NP_756884.1 26250844 1039269 4808228..4811047 1 NC_004431.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4811047 sucA 1039269 sucA Escherichia coli CFT073 2-oxoglutarate dehydrogenase E1 NP_756884.1 4808228 D 199310 CDS NP_756885.1 26250845 1039265 complement(4810920..4811120) 1 NC_004431.1 hypothetical protein 4811120 1039265 c5033 Escherichia coli CFT073 hypothetical protein NP_756885.1 4810920 R 199310 CDS NP_756886.1 26250846 1039262 4811179..4812234 1 NC_004431.1 Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4812234 1039262 c5034 Escherichia coli CFT073 dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex NP_756886.1 4811179 D 199310 CDS NP_756887.1 26250847 1039261 4812246..4813664 1 NC_004431.1 Residues 1 to 468 of 472 are 49.04 pct identical to residues 1 to 470 of 474 from SwissProt.40 : >sp|P52992|DLDH_ALCEU DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX); 2-oxoglutarate dehydrogenase 4813664 1039261 c5035 Escherichia coli CFT073 2-oxoglutarate dehydrogenase NP_756887.1 4812246 D 199310 CDS NP_756888.1 26250848 1039258 4813686..4814855 1 NC_004431.1 Escherichia coli K-12 ortholog: b0728; Escherichia coli O157:H7 ortholog: z0882; succinyl-CoA synthetase subunit beta 4814855 1039258 c5036 Escherichia coli CFT073 succinyl-CoA synthetase subunit beta NP_756888.1 4813686 D 199310 CDS NP_756889.1 26250849 1039251 4814868..4815740 1 NC_004431.1 Escherichia coli K-12 ortholog: b0729; Escherichia coli O157:H7 ortholog: z0883; succinyl-CoA synthetase subunit alpha 4815740 1039251 c5037 Escherichia coli CFT073 succinyl-CoA synthetase subunit alpha NP_756889.1 4814868 D 199310 CDS NP_756890.1 26250850 1039246 4815946..4817451 1 NC_004431.1 Residues 10 to 499 of 501 are 60.28 pct identical to residues 20 to 511 of 513 from SwissProt.40 : >sp|Q07252|MEMP_ALCEU MEMBRANE PROTEIN; membrane-bound protein 4817451 1039246 c5038 Escherichia coli CFT073 membrane-bound protein NP_756890.1 4815946 D 199310 CDS NP_756891.1 26250851 1039244 4817427..4818536 1 NC_004431.1 Residues 15 to 344 of 369 are 44.87 pct identical to residues 1 to 332 of 349 from SwissProt.40 : >sp|Q07251|LDH_ALCEU L-lactate dehydrogenase; lactate dehydrogenase 4818536 1039244 c5039 Escherichia coli CFT073 lactate dehydrogenase NP_756891.1 4817427 D 199310 CDS NP_756892.1 26250852 1039243 complement(4818525..4819883) 1 NC_004431.1 Residues 10 to 441 of 452 are 51.61 pct identical to residues 7 to 439 of 448 from SwissProt.40 : >sp|P10046|DCTD_RHILE C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD; c4-dicarboxylate transport transcriptional regulatory protein 4819883 1039243 c5040 Escherichia coli CFT073 c4-dicarboxylate transport transcriptional regulatory protein NP_756892.1 4818525 R 199310 CDS NP_756893.1 26250853 1039242 complement(4819876..4821696) 1 NC_004431.1 Residues 20 to 591 of 606 are 31.81 pct identical to residues 28 to 612 of 633 from GenPept.129 : >gb|AAG04725.1|AE004563_2 (AE004563) probable two-component sensor [Pseudomonas aeruginosa]; transport sensor protein 4821696 1039242 c5041 Escherichia coli CFT073 transport sensor protein NP_756893.1 4819876 R 199310 CDS NP_756894.1 26250854 1039240 4821518..4821652 1 NC_004431.1 hypothetical protein 4821652 1039240 c5042 Escherichia coli CFT073 hypothetical protein NP_756894.1 4821518 D 199310 CDS NP_756895.1 26250855 1039227 complement(4821668..4821808) 1 NC_004431.1 hypothetical protein 4821808 1039227 c5043 Escherichia coli CFT073 hypothetical protein NP_756895.1 4821668 R 199310 CDS NP_756896.1 26250856 1039221 4821812..4821964 1 NC_004431.1 hypothetical protein 4821964 1039221 c5044 Escherichia coli CFT073 hypothetical protein NP_756896.1 4821812 D 199310 CDS NP_756897.1 26250857 1039218 4821973..4822686 1 NC_004431.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4822686 aphA 1039218 aphA Escherichia coli CFT073 acid phosphatase/phosphotransferase NP_756897.1 4821973 D 199310 CDS NP_756898.1 26250858 1039217 4822797..4823213 1 NC_004431.1 Escherichia coli K-12 ortholog: b4056; Escherichia coli O157:H7 ortholog: z5655; hypothetical protein 4823213 yjbQ 1039217 yjbQ Escherichia coli CFT073 hypothetical protein NP_756898.1 4822797 D 199310 CDS NP_756899.1 26250859 1039214 4823217..4823573 1 NC_004431.1 Escherichia coli K-12 ortholog: b4057; Escherichia coli O157:H7 ortholog: z5656; hypothetical protein 4823573 yjbR 1039214 yjbR Escherichia coli CFT073 hypothetical protein NP_756899.1 4823217 D 199310 CDS NP_756900.1 26250860 1039212 complement(4823608..4826430) 1 NC_004431.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4826430 uvrA 1039212 uvrA Escherichia coli CFT073 excinuclease ABC subunit A NP_756900.1 4823608 R 199310 CDS NP_756901.1 26250861 1039210 4826685..4827221 1 NC_004431.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4827221 ssb 1039210 ssb Escherichia coli CFT073 single-stranded DNA-binding protein NP_756901.1 4826685 D 199310 CDS NP_756902.1 26250862 1039209 complement(4827320..4827700) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4060; Escherichia coli O157:H7 ortholog: z5659; hypothetical protein 4827700 yjcB 1039209 yjcB Escherichia coli CFT073 hypothetical protein NP_756902.1 4827320 R 199310 CDS NP_756903.1 26250863 1039207 4827688..4827822 1 NC_004431.1 hypothetical protein 4827822 1039207 c5051 Escherichia coli CFT073 hypothetical protein NP_756903.1 4827688 D 199310 CDS NP_756904.1 26250864 1039201 4828021..4829583 1 NC_004431.1 Escherichia coli K-12 ortholog: b4061; Escherichia coli O157:H7 ortholog: z5660; hypothetical protein 4829583 yjcC 1039201 yjcC Escherichia coli CFT073 hypothetical protein NP_756904.1 4828021 D 199310 CDS NP_756905.1 26250865 1039200 complement(4829619..4829942) 1 NC_004431.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4829942 soxS 1039200 soxS Escherichia coli CFT073 DNA-binding transcriptional regulator SoxS NP_756905.1 4829619 R 199310 CDS NP_756906.1 26250866 1039198 4830028..4830492 1 NC_004431.1 Escherichia coli K-12 ortholog: b4063; Escherichia coli O157:H7 ortholog: z5662; redox-sensitive transcriptional activator SoxR 4830492 soxR 1039198 soxR Escherichia coli CFT073 redox-sensitive transcriptional activator SoxR NP_756906.1 4830028 D 199310 CDS NP_756907.1 26250867 1039186 4830900..4831139 1 NC_004431.1 hypothetical protein 4831139 1039186 c5055 Escherichia coli CFT073 hypothetical protein NP_756907.1 4830900 D 199310 CDS NP_756908.1 26250868 1039185 4831040..4832389 1 NC_004431.1 Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z5663; hypothetical protein 4832389 1039185 c5056 Escherichia coli CFT073 hypothetical protein NP_756908.1 4831040 D 199310 CDS NP_756909.1 26250869 1039181 4832540..4834189 1 NC_004431.1 Escherichia coli K-12 ortholog: b4065; Escherichia coli O157:H7 ortholog: z5664; Na(+)/H(+) exchanger yjcE 4834189 1039181 c5057 Escherichia coli CFT073 Na(+)/H(+) exchanger yjcE NP_756909.1 4832540 D 199310 CDS NP_756910.1 26250870 1039175 complement(4834225..4835109) 1 NC_004431.1 Residues 1 to 291 of 294 are 89.04 pct identical to residues 1 to 292 of 295 from GenPept.129 : >emb|CAD09254.1| (AL627282) lysR family regulatory protein [Salmonella enterica subsp. enterica serovar Typhi]; transcriptional regulator 4835109 1039175 c5058 Escherichia coli CFT073 transcriptional regulator NP_756910.1 4834225 R 199310 CDS NP_756911.1 26250871 1039169 4835121..4835249 1 NC_004431.1 hypothetical protein 4835249 1039169 c5059 Escherichia coli CFT073 hypothetical protein NP_756911.1 4835121 D 199310 CDS NP_756912.1 26250872 1039166 4835219..4835623 1 NC_004431.1 Residues 1 to 133 of 134 are 84.96 pct identical to residues 3 to 135 of 136 from GenPept.129 : >gb|AAL23095.1| (AE008900) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 4835623 1039166 c5060 Escherichia coli CFT073 hypothetical protein NP_756912.1 4835219 D 199310 CDS NP_756913.1 26250873 1039162 4835616..4836305 1 NC_004431.1 Residues 1 to 229 of 229 are 89.95 pct identical to residues 1 to 229 of 229 from GenPept.129 : >gb|AAL23096.1| (AE008900) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 4836305 1039162 c5061 Escherichia coli CFT073 hypothetical protein NP_756913.1 4835616 D 199310 CDS NP_756914.1 26250874 1039154 complement(4836344..4837993) 1 NC_004431.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4837993 actP 1039154 actP Escherichia coli CFT073 acetate permease NP_756914.1 4836344 R 199310 CDS NP_756915.1 26250875 1039152 complement(4837990..4838307) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4068; Escherichia coli O157:H7 ortholog: z5667; hypothetical protein 4838307 yjcH 1039152 yjcH Escherichia coli CFT073 hypothetical protein NP_756915.1 4837990 R 199310 CDS NP_756916.1 26250876 1039151 complement(4838698..4840656) 1 NC_004431.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4840656 acs 1039151 acs Escherichia coli CFT073 acetyl-CoA synthetase NP_756916.1 4838698 R 199310 CDS NP_756917.1 26250877 1038787 4840930..4841127 1 NC_004431.1 hypothetical protein 4841127 1038787 c5065 Escherichia coli CFT073 hypothetical protein NP_756917.1 4840930 D 199310 CDS NP_756918.1 26250878 1038754 4841048..4842484 1 NC_004431.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4842484 nrfA 1038754 nrfA Escherichia coli CFT073 cytochrome c552 NP_756918.1 4841048 D 199310 CDS NP_756919.1 26250879 1038752 4842523..4843095 1 NC_004431.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4843095 nrfB 1038752 nrfB Escherichia coli CFT073 cytochrome c nitrite reductase pentaheme subunit NP_756919.1 4842523 D 199310 CDS NP_756920.1 26250880 1038749 4843092..4843763 1 NC_004431.1 Escherichia coli K-12 ortholog: b4072; Escherichia coli O157:H7 ortholog: z5671; NrfC protein 4843763 nrfC 1038749 nrfC Escherichia coli CFT073 NrfC protein NP_756920.1 4843092 D 199310 CDS NP_756921.1 26250881 1038748 4843760..4844716 1 NC_004431.1 Escherichia coli K-12 ortholog: b4073; Escherichia coli O157:H7 ortholog: z5672; NrfD protein 4844716 nrfD 1038748 nrfD Escherichia coli CFT073 NrfD protein NP_756921.1 4843760 D 199310 CDS NP_756922.1 26250882 1038747 4844772..4846454 1 NC_004431.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4846454 nrfE 1038747 nrfE Escherichia coli CFT073 heme lyase subunit NrfE NP_756922.1 4844772 D 199310 CDS NP_756923.1 26250883 1038746 4846447..4846830 1 NC_004431.1 Escherichia coli K-12 ortholog: b4075; Escherichia coli O157:H7 ortholog: z5674; formate-dependent nitrite reductase complex subunit NrfF 4846830 nrfF 1038746 nrfF Escherichia coli CFT073 formate-dependent nitrite reductase complex subunit NrfF NP_756923.1 4846447 D 199310 CDS NP_756924.1 26250884 1038744 4846827..4847423 1 NC_004431.1 Escherichia coli K-12 ortholog: b4076; Escherichia coli O157:H7 ortholog: z5675; formate-dependent nitrite reductase complex subunit NrfG 4847423 nrfG 1038744 nrfG Escherichia coli CFT073 formate-dependent nitrite reductase complex subunit NrfG NP_756924.1 4846827 D 199310 CDS NP_756925.1 26250885 1038743 complement(4847558..4847689) 1 NC_004431.1 hypothetical protein 4847689 1038743 c5073 Escherichia coli CFT073 hypothetical protein NP_756925.1 4847558 R 199310 CDS NP_756926.1 26250886 1038742 4847766..4849079 1 NC_004431.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4849079 gltP 1038742 gltP Escherichia coli CFT073 glutamate/aspartate:proton symporter NP_756926.1 4847766 D 199310 CDS NP_756927.1 26250887 1038667 4849989..4850147 1 NC_004431.1 hypothetical protein 4850147 1038667 c5075 Escherichia coli CFT073 hypothetical protein NP_756927.1 4849989 D 199310 CDS NP_756928.1 26250888 1038642 complement(4850133..4850876) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4078; Escherichia coli O157:H7 ortholog: z5677; hypothetical protein 4850876 yjcO 1038642 yjcO Escherichia coli CFT073 hypothetical protein NP_756928.1 4850133 R 199310 CDS NP_756929.1 26250889 1038604 complement(4850933..4851637) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1483; Escherichia coli O157:H7 ortholog: z2227; ABC transporter ATP-binding protein 4851637 yddO 1038604 yddO Escherichia coli CFT073 ABC transporter ATP-binding protein NP_756929.1 4850933 R 199310 CDS NP_756930.1 26250890 1038590 complement(4851624..4852520) 1 NC_004431.1 Residues 21 to 287 of 298 are 62.98 pct identical to residues 1 to 281 of 292 from GenPept.129 : >emb|CAC92681.1| (AJ414157) ABC transporter transporter, ATP-binding protein [Yersinia pestis]; oligopeptide ABC transporter 4852520 1038590 c5078 Escherichia coli CFT073 oligopeptide ABC transporter NP_756930.1 4851624 R 199310 CDS NP_756931.1 26250891 1038569 complement(4852453..4853286) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1485; Escherichia coli O157:H7 ortholog: z2225; ABC transporter permease 4853286 yddQ 1038569 yddQ Escherichia coli CFT073 ABC transporter permease NP_756931.1 4852453 R 199310 CDS NP_756932.1 26250892 1038560 complement(4853286..4854428) 1 NC_004431.1 Escherichia coli K-12 ortholog: b1486; Escherichia coli O157:H7 ortholog: z2224; ABC transporter permease 4854428 yddR 1038560 yddR Escherichia coli CFT073 ABC transporter permease NP_756932.1 4853286 R 199310 CDS NP_756933.1 26250893 1038557 complement(4854435..4856003) 1 NC_004431.1 Residues 9 to 506 of 522 are 28.96 pct identical to residues 14 to 499 of 516 from MG1655 : b1487; hypothetical protein 4856003 1038557 c5081 Escherichia coli CFT073 hypothetical protein NP_756933.1 4854435 R 199310 CDS NP_756934.1 26250894 1038553 complement(4856378..4858525) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4079; Escherichia coli O157:H7 ortholog: z5678; formate dehydrogenase H 4858525 fdhF 1038553 fdhF Escherichia coli CFT073 formate dehydrogenase H NP_756934.1 4856378 R 199310 CDS NP_756935.1 26250895 1038551 4858103..4858489 1 NC_004431.1 hypothetical protein 4858489 1038551 c5083 Escherichia coli CFT073 hypothetical protein NP_756935.1 4858103 D 199310 CDS NP_756936.1 26250896 1038549 complement(4858723..4860189) 1 NC_004431.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4860189 yjcP 1038549 yjcP Escherichia coli CFT073 outer membrane efflux protein MdtP NP_756936.1 4858723 R 199310 CDS NP_756937.1 26250897 1038545 complement(4860186..4862237) 1 NC_004431.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4862237 yjcQ 1038545 yjcQ Escherichia coli CFT073 multidrug efflux system protein MdtO NP_756937.1 4860186 R 199310 CDS NP_756938.1 26250898 1038544 complement(4862237..4863268) 1 NC_004431.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4863268 yjcR 1038544 yjcR Escherichia coli CFT073 multidrug resistance protein MdtN NP_756938.1 4862237 R 199310 CDS NP_756939.1 26250899 1038520 complement(4863287..4863610) 1 NC_004431.1 Residues 17 to 107 of 107 are 95.60 pct identical to residues 1 to 91 of 91 from GenPept.129 : >dbj|BAB38488.1| (AP002568) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 4863610 1038520 c5088 Escherichia coli CFT073 hypothetical protein NP_756939.1 4863287 R 199310 CDS NP_756940.1 26250900 1038518 complement(4863771..4865768) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4083; Escherichia coli O157:H7 ortholog: z5683; hypothetical protein 4865768 yjcS 1038518 yjcS Escherichia coli CFT073 hypothetical protein NP_756940.1 4863771 R 199310 CDS NP_756941.1 26250901 1038491 complement(4866029..4866958) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4084; D-allose kinase 4866958 yjcT 1038491 yjcT Escherichia coli CFT073 D-allose kinase NP_756941.1 4866029 R 199310 CDS NP_756942.1 26250902 1038475 complement(4866942..4867643) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4085; allulose-6-phosphate 3-epimerase 4867643 yjcU 1038475 yjcU Escherichia coli CFT073 allulose-6-phosphate 3-epimerase NP_756942.1 4866942 R 199310 CDS NP_756943.1 26250903 1038473 complement(4867648..4868628) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4086; Escherichia coli O157:H7 ortholog: z5251; D-allose transporter subunit 4868628 yjcV 1038473 yjcV Escherichia coli CFT073 D-allose transporter subunit NP_756943.1 4867648 R 199310 CDS NP_756944.1 26250904 1038396 complement(4868607..4870139) 1 NC_004431.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4870139 yjcW 1038396 yjcW Escherichia coli CFT073 D-allose transporter ATP-binding protein NP_756944.1 4868607 R 199310 CDS NP_756945.1 26250905 1038350 complement(4870266..4871207) 1 NC_004431.1 ALBP; Escherichia coli K-12 ortholog: b4088; D-allose transporter subunit 4871207 yjcX 1038350 yjcX Escherichia coli CFT073 D-allose transporter subunit NP_756945.1 4870266 R 199310 CDS NP_756946.2 161486022 1038300 complement(4871260..4872150) 1 NC_004431.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4872150 rpiR 1038300 rpiR Escherichia coli CFT073 DNA-binding transcriptional repressor RpiR NP_756946.2 4871260 R 199310 CDS NP_756947.1 26250907 1038252 4872509..4872958 1 NC_004431.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4872958 rpiB 1038252 rpiB Escherichia coli CFT073 ribose-5-phosphate isomerase B NP_756947.1 4872509 D 199310 CDS NP_756948.1 26250908 1038212 4873027..4873356 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5694; hypothetical protein 4873356 1038212 c5097 Escherichia coli CFT073 hypothetical protein NP_756948.1 4873027 D 199310 CDS NP_756949.1 26250909 1038195 complement(4873384..4874142) 1 NC_004431.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4874142 phnP 1038195 phnP Escherichia coli CFT073 carbon-phosphorus lyase complex accessory protein NP_756949.1 4873384 R 199310 CDS NP_756950.1 26250910 1038175 complement(4874144..4874578) 1 NC_004431.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4874578 phnO 1038175 phnO Escherichia coli CFT073 aminoalkylphosphonic acid N-acetyltransferase NP_756950.1 4874144 R 199310 CDS NP_756951.1 26250911 1038171 complement(4875122..4876258) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4095; Escherichia coli O157:H7 ortholog: z5698; PhnM protein 4876258 phnM 1038171 phnM Escherichia coli CFT073 PhnM protein NP_756951.1 4875122 R 199310 CDS NP_756952.1 26250912 1038082 complement(4876255..4876935) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4096; Escherichia coli O157:H7 ortholog: z5699; phosphonate ABC transporter ATP-binding protein 4876935 phnL 1038082 phnL Escherichia coli CFT073 phosphonate ABC transporter ATP-binding protein NP_756952.1 4876255 R 199310 CDS NP_756953.2 161486021 1038045 complement(4877046..4877804) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4097; Escherichia coli O157:H7 ortholog: z5700; phosphonate C-P lyase system protein PhnK 4877804 phnK 1038045 phnK Escherichia coli CFT073 phosphonate C-P lyase system protein PhnK NP_756953.2 4877046 R 199310 CDS NP_756954.1 26250914 1038043 complement(4877801..4878730) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4098; Escherichia coli O157:H7 ortholog: z5701; PhnJ protein 4878730 phnJ 1038043 phnJ Escherichia coli CFT073 PhnJ protein NP_756954.1 4877801 R 199310 CDS NP_756955.1 26250915 1038042 complement(4878639..4879709) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4099; Escherichia coli O157:H7 ortholog: z5702; PhnI protein 4879709 phnI 1038042 phnI Escherichia coli CFT073 PhnI protein NP_756955.1 4878639 R 199310 CDS NP_756956.1 26250916 1038039 complement(4879703..4880287) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4100; Escherichia coli O157:H7 ortholog: z5703; carbon-phosphorus lyase complex subunit 4880287 phnH 1038039 phnH Escherichia coli CFT073 carbon-phosphorus lyase complex subunit NP_756956.1 4879703 R 199310 CDS NP_756957.1 26250917 1038038 complement(4880284..4880736) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4101; Escherichia coli O157:H7 ortholog: z5704; PhnG protein 4880736 phnG 1038038 phnG Escherichia coli CFT073 PhnG protein NP_756957.1 4880284 R 199310 CDS NP_756958.1 26250918 1038037 complement(4880737..4881471) 1 NC_004431.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4881471 phnF 1038037 phnF Escherichia coli CFT073 phosphonate metabolism transcriptional regulator PhnF NP_756958.1 4880737 R 199310 CDS NP_756959.1 26250919 1038031 complement(4881483..4882325) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5706; membrane channel protein component of Pn transporter 4882325 phnE 1038031 phnE Escherichia coli CFT073 membrane channel protein component of Pn transporter NP_756959.1 4881483 R 199310 CDS NP_756960.1 26250920 1038026 complement(4882368..4883384) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4105; Escherichia coli O157:H7 ortholog: z5707; phosphonates-binding periplasmic protein 4883384 phnD 1038026 phnD Escherichia coli CFT073 phosphonates-binding periplasmic protein NP_756960.1 4882368 R 199310 CDS NP_756961.1 26250921 1038016 complement(4883409..4884197) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4106; Escherichia coli O157:H7 ortholog: z5708; phosphonate/organophosphate ester transporter subunit 4884197 phnC 1038016 phnC Escherichia coli CFT073 phosphonate/organophosphate ester transporter subunit NP_756961.1 4883409 R 199310 CDS NP_756962.1 26250922 1037984 complement(4884330..4884773) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4107; Escherichia coli O157:H7 ortholog: z5709; hypothetical protein 4884773 phnB 1037984 phnB Escherichia coli CFT073 hypothetical protein NP_756962.1 4884330 R 199310 CDS NP_756963.1 26250923 1037973 complement(4884933..4885415) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4108; Escherichia coli O157:H7 ortholog: z5710; PhnA protein 4885415 phnA 1037973 phnA Escherichia coli CFT073 PhnA protein NP_756963.1 4884933 R 199310 CDS NP_756964.1 26250924 1037942 4885671..4887899 1 NC_004431.1 Escherichia coli K-12 ortholog: b4109; Escherichia coli O157:H7 ortholog: z5711; hypothetical protein 4887899 yjdA 1037942 yjdA Escherichia coli CFT073 hypothetical protein NP_756964.1 4885671 D 199310 CDS NP_756965.1 26250925 1037941 4887896..4888774 1 NC_004431.1 Escherichia coli K-12 ortholog: b4110; Escherichia coli O157:H7 ortholog: z5712; hypothetical protein 4888774 yjcZ 1037941 yjcZ Escherichia coli CFT073 hypothetical protein NP_756965.1 4887896 D 199310 CDS NP_756966.1 26250926 1037931 4889005..4890540 1 NC_004431.1 Proline porter II; Escherichia coli K-12 ortholog: b4111; Escherichia coli O157:H7 ortholog: z5713; proline/glycine betaine transporter 4890540 proP 1037931 proP Escherichia coli CFT073 proline/glycine betaine transporter NP_756966.1 4889005 D 199310 CDS NP_756967.1 26250927 1037924 complement(4890717..4891817) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4112; Escherichia coli O157:H7 ortholog: z5714; sensor protein BasS/PmrB 4891817 basS 1037924 basS Escherichia coli CFT073 sensor protein BasS/PmrB NP_756967.1 4890717 R 199310 CDS NP_756968.1 26250928 1037919 complement(4891818..4892486) 1 NC_004431.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4892486 basR 1037919 basR Escherichia coli CFT073 DNA-binding transcriptional regulator BasR NP_756968.1 4891818 R 199310 CDS NP_756969.2 229106361 1037911 complement(4892483..4894156) 1 NC_004431.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4894156 yjdB 1037911 yjdB Escherichia coli CFT073 cell division protein NP_756969.2 4892483 R 199310 CDS NP_756970.1 26250930 1037910 complement(4894230..4895567) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4115; Escherichia coli O157:H7 ortholog: z5717; arginine:agmatin antiporter 4895567 yjdE 1037910 yjdE Escherichia coli CFT073 arginine:agmatin antiporter NP_756970.1 4894230 R 199310 CDS NP_756971.1 26250931 1037907 complement(4895704..4896465) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4116; Escherichia coli O157:H7 ortholog: z5718; regulatory protein adiY 4896465 adiY 1037907 adiY Escherichia coli CFT073 regulatory protein adiY NP_756971.1 4895704 R 199310 CDS NP_756972.1 26250932 1037903 complement(4896801..4899071) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4117; Escherichia coli O157:H7 ortholog: z5719; biodegradative arginine decarboxylase 4899071 adiA 1037903 adiA Escherichia coli CFT073 biodegradative arginine decarboxylase NP_756972.1 4896801 R 199310 CDS NP_756973.1 26250933 1037902 complement(4899267..4900175) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4118; Escherichia coli O157:H7 ortholog: z5720; DNA-binding transcriptional regulator MelR 4900175 melR 1037902 melR Escherichia coli CFT073 DNA-binding transcriptional regulator MelR NP_756973.1 4899267 R 199310 CDS NP_756974.1 26250934 1037886 4900458..4901813 1 NC_004431.1 Escherichia coli K-12 ortholog: b4119; Escherichia coli O157:H7 ortholog: z5721; alpha-galactosidase 4901813 melA 1037886 melA Escherichia coli CFT073 alpha-galactosidase NP_756974.1 4900458 D 199310 CDS NP_756975.1 26250935 1037869 complement(4902575..4904221) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4122; Escherichia coli O157:H7 ortholog: z5724; fumarate hydratase class I, anaerobic 4904221 fumB 1037869 fumB Escherichia coli CFT073 fumarate hydratase class I, anaerobic NP_756975.1 4902575 R 199310 CDS NP_756976.1 26250936 1037862 complement(4904299..4905639) 1 NC_004431.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4905639 dcuB 1037862 dcuB Escherichia coli CFT073 anaerobic C4-dicarboxylate transporter NP_756976.1 4904299 R 199310 CDS NP_756977.1 26250937 1037775 4905707..4905865 1 NC_004431.1 hypothetical protein 4905865 1037775 c5129 Escherichia coli CFT073 hypothetical protein NP_756977.1 4905707 D 199310 CDS NP_756978.1 26250938 1037751 complement(4906210..4906929) 1 NC_004431.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4906929 yjdG 1037751 yjdG Escherichia coli CFT073 DNA-binding transcriptional activator DcuR NP_756978.1 4906210 R 199310 CDS NP_756979.1 26250939 1037750 complement(4906926..4908557) 1 NC_004431.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4908557 yjdH 1037750 yjdH Escherichia coli CFT073 sensory histidine kinase DcuS NP_756979.1 4906926 R 199310 CDS NP_756980.1 26250940 1037721 4908549..4908683 1 NC_004431.1 hypothetical protein 4908683 1037721 c5132 Escherichia coli CFT073 hypothetical protein NP_756980.1 4908549 D 199310 CDS NP_756981.1 26250941 1037716 4908738..4908968 1 NC_004431.1 Escherichia coli K-12 ortholog: b4126; Escherichia coli O157:H7 ortholog: z5728; hypothetical protein 4908968 yjdI 1037716 yjdI Escherichia coli CFT073 hypothetical protein NP_756981.1 4908738 D 199310 CDS NP_756982.1 26250942 1037704 4908980..4909252 1 NC_004431.1 Escherichia coli K-12 ortholog: b4127; Escherichia coli O157:H7 ortholog: z5729; hypothetical protein 4909252 yjdJ 1037704 yjdJ Escherichia coli CFT073 hypothetical protein NP_756982.1 4908980 D 199310 CDS NP_756983.1 26250943 1037701 complement(4909009..4909461) 1 NC_004431.1 hypothetical protein 4909461 1037701 c5135 Escherichia coli CFT073 hypothetical protein NP_756983.1 4909009 R 199310 CDS NP_756984.1 26250944 1037700 4909805..4909978 1 NC_004431.1 Escherichia coli K-12 ortholog: b1445; Escherichia coli O157:H7 ortholog: z5731; hypothetical protein 4909978 1037700 c5136 Escherichia coli CFT073 hypothetical protein NP_756984.1 4909805 D 199310 CDS NP_756985.1 26250945 1037696 4909988..4910131 1 NC_004431.1 hypothetical protein 4910131 1037696 c5137 Escherichia coli CFT073 hypothetical protein NP_756985.1 4909988 D 199310 CDS NP_756986.2 161486020 1037694 complement(4910097..4911614) 1 NC_004431.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4911614 lysS 1037694 lysS Escherichia coli CFT073 lysyl-tRNA synthetase NP_756986.2 4910097 R 199310 CDS NP_756987.1 26250947 1037691 complement(4911851..4913308) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4130; Escherichia coli O157:H7 ortholog: z5733; transporter YjdL 4913308 yjdL 1037691 yjdL Escherichia coli CFT073 transporter YjdL NP_756987.1 4911851 R 199310 CDS NP_756988.1 26250948 1037690 complement(4913367..4915520) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4131; Escherichia coli O157:H7 ortholog: z5734; lysine decarboxylase, inducible 4915520 cadA 1037690 cadA Escherichia coli CFT073 lysine decarboxylase, inducible NP_756988.1 4913367 R 199310 CDS NP_756989.1 26250949 1037689 complement(4915594..4916928) 1 NC_004431.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4916928 cadB 1037689 cadB Escherichia coli CFT073 lysine/cadaverine antiporter NP_756989.1 4915594 R 199310 CDS NP_756990.1 26250950 1037687 complement(4917294..4918832) 1 NC_004431.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4918832 cadC 1037687 cadC Escherichia coli CFT073 DNA-binding transcriptional activator CadC NP_756990.1 4917294 R 199310 CDS NP_756991.1 26250951 1037686 complement(4919569..4919811) 1 NC_004431.1 Residues 1 to 80 of 80 are 100.00 pct identical to residues 1 to 80 of 80 from GenPept.129 : >gb|AAL67384.1|AF447814_52 (AF447814) L0012-like protein [Escherichia coli]; hypothetical protein 4919811 1037686 c5143 Escherichia coli CFT073 hypothetical protein NP_756991.1 4919569 R 199310 CDS NP_756992.1 26250952 1037685 4920004..4921503 1 NC_004431.1 Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein 4921503 1037685 c5144 Escherichia coli CFT073 hypothetical protein NP_756992.1 4920004 D 199310 CDS NP_756993.1 26250953 1037683 4921500..4922255 1 NC_004431.1 Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 4922255 1037683 c5145 Escherichia coli CFT073 hypothetical protein NP_756993.1 4921500 D 199310 CDS NP_756994.1 26250954 1037682 complement(4922315..4922839) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 4922839 1037682 c5146 Escherichia coli CFT073 hypothetical protein NP_756994.1 4922315 R 199310 CDS NP_756995.1 26250955 1037681 complement(4922924..4923121) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1663; hypothetical protein 4923121 1037681 c5147 Escherichia coli CFT073 hypothetical protein NP_756995.1 4922924 R 199310 CDS NP_756996.1 26250956 1037680 complement(4923133..4923621) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5092; hypothetical protein 4923621 1037680 c5148 Escherichia coli CFT073 hypothetical protein NP_756996.1 4923133 R 199310 CDS NP_756997.1 26250957 1037679 complement(4923618..4923995) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 4923995 1037679 c5149 Escherichia coli CFT073 hypothetical protein NP_756997.1 4923618 R 199310 CDS NP_756998.1 26250958 1037677 complement(4924085..4924513) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein 4924513 1037677 c5150 Escherichia coli CFT073 hypothetical protein NP_756998.1 4924085 R 199310 CDS NP_756999.1 26250959 1037676 complement(4924532..4924753) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 4924753 1037676 c5151 Escherichia coli CFT073 hypothetical protein NP_756999.1 4924532 R 199310 CDS NP_757000.1 26250960 1037675 complement(4924822..4925298) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 4925298 1037675 c5152 Escherichia coli CFT073 radC-like protein yeeS NP_757000.1 4924822 R 199310 CDS NP_757001.1 26250961 1037672 4924834..4925364 1 NC_004431.1 Residues 1 to 156 of 176 are 91.02 pct identical to residues 1 to 156 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 4925364 1037672 c5153 Escherichia coli CFT073 hypothetical protein NP_757001.1 4924834 D 199310 CDS NP_757002.1 26250962 1037671 4925298..4925744 1 NC_004431.1 Residues 6 to 143 of 148 are 86.95 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 4925744 1037671 c5154 Escherichia coli CFT073 hypothetical protein NP_757002.1 4925298 D 199310 CDS NP_757003.1 26250963 1037670 complement(4925313..4925798) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 4925798 1037670 c5155 Escherichia coli CFT073 hypothetical protein NP_757003.1 4925313 R 199310 CDS NP_757004.1 26250964 1037669 complement(4925889..4926707) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 4926707 1037669 c5156 Escherichia coli CFT073 hypothetical protein NP_757004.1 4925889 R 199310 CDS NP_757005.1 26250965 1037667 complement(4926797..4927030) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0249; hypothetical protein 4927030 1037667 c5157 Escherichia coli CFT073 hypothetical protein NP_757005.1 4926797 R 199310 CDS NP_757006.1 26250966 1037663 complement(4927036..4927818) 1 NC_004431.1 Residues 1 to 161 of 260 are 100.00 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4927818 1037663 c5158 Escherichia coli CFT073 hypothetical protein NP_757006.1 4927036 R 199310 CDS NP_757007.1 26250967 1037662 4927846..4927977 1 NC_004431.1 hypothetical protein 4927977 1037662 c5159 Escherichia coli CFT073 hypothetical protein NP_757007.1 4927846 D 199310 CDS NP_757008.1 26250968 1037659 complement(4927861..4928541) 1 NC_004431.1 Escherichia coli K-12 ortholog: b2634; transcriptional regulator YfjR 4928541 1037659 c5160 Escherichia coli CFT073 transcriptional regulator YfjR NP_757008.1 4927861 R 199310 CDS NP_757009.1 26250969 1037657 complement(4928570..4928725) 1 NC_004431.1 hypothetical protein 4928725 1037657 c5161 Escherichia coli CFT073 hypothetical protein NP_757009.1 4928570 R 199310 CDS NP_757010.1 26250970 1037655 complement(4928744..4929628) 1 NC_004431.1 Residues 12 to 294 of 294 are 35.33 pct identical to residues 12 to 289 of 289 from MG1655 : b2632; hypothetical protein 4929628 1037655 c5162 Escherichia coli CFT073 hypothetical protein NP_757010.1 4928744 R 199310 CDS NP_757011.1 26250971 1037654 4929731..4930684 1 NC_004431.1 Residues 2 to 317 of 317 are 100.00 pct identical to residues 1 to 316 of 316 from GenPept.129 : >gb|AAL67396.1|AF447814_64 (AF447814) unknown [Escherichia coli]; hypothetical protein 4930684 1037654 c5163 Escherichia coli CFT073 hypothetical protein NP_757011.1 4929731 D 199310 CDS NP_757012.1 26250972 1037653 complement(4930681..4931556) 1 NC_004431.1 Residues 30 to 274 of 291 are 100.00 pct identical to residues 1 to 245 of 254 from GenPept.129 : >gb|AAL67397.1|AF447814_65 (AF447814) unknown [Escherichia coli]; hypothetical protein 4931556 1037653 c5164 Escherichia coli CFT073 hypothetical protein NP_757012.1 4930681 R 199310 CDS NP_757013.1 26250973 1037652 4930708..4930890 1 NC_004431.1 hypothetical protein 4930890 1037652 c5165 Escherichia coli CFT073 hypothetical protein NP_757013.1 4930708 D 199310 CDS NP_757014.1 26250974 1037651 complement(4931923..4932141) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1647; partial transposase 4932141 1037651 c5166 Escherichia coli CFT073 partial transposase NP_757014.1 4931923 R 199310 CDS NP_757015.1 26250975 1037648 complement(4932138..4932815) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 4932815 1037648 c5167 Escherichia coli CFT073 transposase IS629 NP_757015.1 4932138 R 199310 CDS NP_757016.1 26250976 1037647 complement(4932812..4933138) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 4933138 1037647 c5168 Escherichia coli CFT073 hypothetical protein NP_757016.1 4932812 R 199310 CDS NP_757017.1 26250977 1037645 4933881..4934117 1 NC_004431.1 Residues 1 to 78 of 78 are 100.00 pct identical to residues 1 to 78 of 78 from GenPept.129 : >gb|AAL67400.1|AF447814_68 (AF447814) unknown [Escherichia coli]; hypothetical protein 4934117 1037645 c5169 Escherichia coli CFT073 hypothetical protein NP_757017.1 4933881 D 199310 CDS NP_757018.1 26250978 1037642 complement(4934123..4934371) 1 NC_004431.1 hypothetical protein 4934371 1037642 c5170 Escherichia coli CFT073 hypothetical protein NP_757018.1 4934123 R 199310 CDS NP_757019.1 26250979 1037640 4934166..4934432 1 NC_004431.1 hypothetical protein 4934432 1037640 c5171 Escherichia coli CFT073 hypothetical protein NP_757019.1 4934166 D 199310 CDS NP_757020.1 26250980 1037639 4934476..4935216 1 NC_004431.1 Residues 1 to 246 of 246 are 100.00 pct identical to residues 1 to 246 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4935216 1037639 c5172 Escherichia coli CFT073 hypothetical protein NP_757020.1 4934476 D 199310 CDS NP_757021.1 26250981 1037631 4935304..4935522 1 NC_004431.1 hypothetical protein 4935522 1037631 c5173 Escherichia coli CFT073 hypothetical protein NP_757021.1 4935304 D 199310 CDS NP_757022.1 26250982 1037614 4935990..4938038 1 NC_004431.1 iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein; iron-regulated outer membrane virulence protein 4938038 1037614 c5174 Escherichia coli CFT073 iron-regulated outer membrane virulence protein NP_757022.1 4935990 D 199310 CDS NP_757023.1 26250983 1037609 complement(4938218..4938349) 1 NC_004431.1 Residues 1 to 43 of 43 are 88.37 pct identical to residues 358 to 400 of 400 from GenPept.129 : >gb|AAK69271.1|AF336309_66 (AF336309) unknown [Yersinia enterocolitica]; hypothetical protein 4938349 1037609 c5175 Escherichia coli CFT073 hypothetical protein NP_757023.1 4938218 R 199310 CDS NP_757024.1 26250984 1037605 complement(4938378..4939160) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2082; transposase 4939160 1037605 c5176 Escherichia coli CFT073 transposase NP_757024.1 4938378 R 199310 CDS NP_757025.1 26250985 1037596 4939432..4939758 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5879; hypothetical protein 4939758 1037596 c5177 Escherichia coli CFT073 hypothetical protein NP_757025.1 4939432 D 199310 CDS NP_757026.1 26250986 1037595 4939758..4940645 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 4940645 1037595 c5178 Escherichia coli CFT073 transposase IS629 NP_757026.1 4939758 D 199310 CDS NP_757027.1 26250987 1037594 complement(4940831..4941841) 1 NC_004431.1 Residues 1 to 336 of 336 are 56.72 pct identical to residues 1 to 335 of 335 from SwissProt.40 : >sp|P42188|PRSG_ECOLI FIMBRIAL PROTEIN PRSG PRECURSOR (ADHESIN); PapG protein 4941841 papG_2 1037594 papG_2 Escherichia coli CFT073 PapG protein NP_757027.1 4940831 R 199310 CDS NP_757028.1 26250988 1037591 complement(4941885..4942415) 1 NC_004431.1 Residues 11 to 176 of 176 are 92.81 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P42187|PRSF_ECOLI MINOR FIMBRIAL PROTEIN PRSF PRECURSOR; PapF protein 4942415 papF_2 1037591 papF_2 Escherichia coli CFT073 PapF protein NP_757028.1 4941885 R 199310 CDS NP_757029.1 26250989 1037587 complement(4942460..4942999) 1 NC_004431.1 Residues 7 to 179 of 179 are 91.32 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|P08407|PAPE_ECOLI FIMBRIAL PROTEIN PAPE PRECURSOR; PapE protein 4942999 papE_2 1037587 papE_2 Escherichia coli CFT073 PapE protein NP_757029.1 4942460 R 199310 CDS NP_757030.1 26250990 1037585 complement(4943008..4943547) 1 NC_004431.1 Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 : >sp|P42190|PAPK_ECOLI PROTEIN PAPK PRECURSOR; PapK protein 4943547 papK_2 1037585 papK_2 Escherichia coli CFT073 PapK protein NP_757030.1 4943008 R 199310 CDS NP_757031.1 26250991 1037584 4943153..4943767 1 NC_004431.1 hypothetical protein 4943767 1037584 c5183 Escherichia coli CFT073 hypothetical protein NP_757031.1 4943153 D 199310 CDS NP_757032.1 26250992 1037582 complement(4943554..4944135) 1 NC_004431.1 Residues 1 to 193 of 193 are 96.37 pct identical to residues 1 to 193 of 193 from SwissProt.40 : >sp|P42189|PRSJ_ECOLI PRSJ PROTEIN PRECURSOR; PapJ protein 4944135 papJ_2 1037582 papJ_2 Escherichia coli CFT073 PapJ protein NP_757032.1 4943554 R 199310 CDS NP_757033.1 26250993 1037581 complement(4944172..4944906) 1 NC_004431.1 Residues 3 to 244 of 244 are 40.74 pct identical to residues 9 to 246 of 250 from MG1655 : b2336; PapD protein 4944906 papD_2 1037581 papD_2 Escherichia coli CFT073 PapD protein NP_757033.1 4944172 R 199310 CDS NP_757034.1 26250994 1037579 complement(4944977..4947508) 1 NC_004431.1 Residues 8 to 839 of 843 are 43.20 pct identical to residues 1 to 842 of 879 from EDL933 : z3600; PapC protein 4947508 papC_2 1037579 papC_2 Escherichia coli CFT073 PapC protein NP_757034.1 4944977 R 199310 CDS NP_757035.1 26250995 1037577 complement(4947546..4948133) 1 NC_004431.1 Residues 1 to 195 of 195 are 98.97 pct identical to residues 1 to 195 of 195 from SwissProt.40 : >sp|P42185|PRSH_ECOLI PRS FIMBRIAL MINOR PILIN PROTEIN PRECURSOR; PapH protein 4948133 papH_2 1037577 papH_2 Escherichia coli CFT073 PapH protein NP_757035.1 4947546 R 199310 CDS NP_757036.1 26250996 1037576 complement(4948203..4948799) 1 NC_004431.1 Residues 12 to 198 of 198 are 99.46 pct identical to residues 1 to 187 of 187 from SwissProt.40 : >sp|P04740|FMK1_ECOLI KS71A FIMBRILLIN PRECURSOR (P-FIMBRIAL ANTIGEN); PapA protein 4948799 papA_2 1037576 papA_2 Escherichia coli CFT073 PapA protein NP_757036.1 4948203 R 199310 CDS NP_757037.1 26250997 1037573 4949723..4949944 1 NC_004431.1 Residues 1 to 73 of 73 are 100.00 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P25395|KS7A_ECOLI P FIMBRIAL REGULATORY PROTEIN KS71A; PapI protein 4949944 papI_2 1037573 papI_2 Escherichia coli CFT073 PapI protein NP_757037.1 4949723 D 199310 CDS NP_757038.1 26250998 1037572 complement(4949967..4950092) 1 NC_004431.1 hypothetical protein 4950092 1037572 c5190 Escherichia coli CFT073 hypothetical protein NP_757038.1 4949967 R 199310 CDS NP_757039.1 26250999 1037570 4950188..4950634 1 NC_004431.1 Residues 1 to 148 of 148 are 100.00 pct identical to residues 1 to 148 of 148 from GenPept.129 : >gb|AAL67420.1|AF447814_88 (AF447814) unknown [Escherichia coli]; hypothetical protein 4950634 1037570 c5191 Escherichia coli CFT073 hypothetical protein NP_757039.1 4950188 D 199310 CDS NP_757040.1 26251000 1037568 complement(4950287..4950520) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1627; hypothetical protein 4950520 1037568 c5192 Escherichia coli CFT073 hypothetical protein NP_757040.1 4950287 R 199310 CDS NP_757041.1 26251001 1037567 complement(4950589..4951305) 1 NC_004431.1 Residues 89 to 238 of 238 are 100.00 pct identical to residues 30 to 179 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli]; hypothetical protein 4951305 1037567 c5193 Escherichia coli CFT073 hypothetical protein NP_757041.1 4950589 R 199310 CDS NP_757042.1 26251002 1037561 complement(4951420..4951572) 1 NC_004431.1 hypothetical protein 4951572 1037561 c5194 Escherichia coli CFT073 hypothetical protein NP_757042.1 4951420 R 199310 CDS NP_757043.1 26251003 1037560 complement(4951662..4951988) 1 NC_004431.1 Residues 4 to 102 of 108 are 32.32 pct identical to residues 7 to 103 of 197 from GenPept.129 : >gb|AAL08430.1|AF326777_5 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 4951988 1037560 c5195 Escherichia coli CFT073 hypothetical protein NP_757043.1 4951662 R 199310 CDS NP_757044.1 26251004 1037559 4952414..4952704 1 NC_004431.1 Escherichia coli K-12 ortholog: b1997; transposase insC 4952704 1037559 c5196 Escherichia coli CFT073 transposase insC NP_757044.1 4952414 D 199310 CDS NP_757045.1 26251005 1037557 4952728..4953375 1 NC_004431.1 Escherichia coli K-12 ortholog: b4273; Escherichia coli O157:H7 ortholog: z1825; transposase insD 4953375 1037557 c5197 Escherichia coli CFT073 transposase insD NP_757045.1 4952728 D 199310 CDS NP_757046.1 26251006 1037556 4953372..4953542 1 NC_004431.1 Residues 1 to 56 of 56 are 96.42 pct identical to residues 66 to 121 of 121 from GenPept.129 : >gb|AAG54583.1|AE005203_12 (AE005203) unknown protein encoded by IS2 [Escherichia coli O157:H7 EDL933]; hypothetical protein 4953542 1037556 c5198 Escherichia coli CFT073 hypothetical protein NP_757046.1 4953372 D 199310 CDS NP_757047.1 26251007 1037555 complement(4953577..4953954) 1 NC_004431.1 hypothetical protein 4953954 1037555 c5199 Escherichia coli CFT073 hypothetical protein NP_757047.1 4953577 R 199310 CDS NP_757048.1 26251008 1037554 4953819..4953944 1 NC_004431.1 hypothetical protein 4953944 1037554 c5200 Escherichia coli CFT073 hypothetical protein NP_757048.1 4953819 D 199310 CDS NP_757049.1 26251009 1037552 complement(4953985..4955349) 1 NC_004431.1 Residues 1 to 406 of 454 are 89.16 pct identical to residues 1 to 405 of 406 from SwissProt.40 : >sp|P12681|PGTP_SALTY Phosphoglycerate transporter protein; transporter protein 4955349 pgtP 1037552 pgtP Escherichia coli CFT073 transporter protein NP_757049.1 4953985 R 199310 CDS NP_757050.1 26251010 1037551 4955658..4956965 1 NC_004431.1 Residues 41 to 435 of 435 are 78.48 pct identical to residues 3 to 397 of 397 from SwissProt.40 : >sp|P37591|PGTC_SALTY PHOSPHOGLYCERATE TRANSPORT REGULATORY PROTEIN PGTC PRECURSOR; regulatory protein 4956965 pgtC 1037551 pgtC Escherichia coli CFT073 regulatory protein NP_757050.1 4955658 D 199310 CDS NP_757051.1 26251011 1037550 4956962..4958971 1 NC_004431.1 Residues 139 to 669 of 669 are 79.28 pct identical to residues 63 to 593 of 593 from SwissProt.40 : >sp|P37433|PGTB_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM SENSOR PROTEIN PGTB; regulatory protein 4958971 pgtB 1037550 pgtB Escherichia coli CFT073 regulatory protein NP_757051.1 4956962 D 199310 CDS NP_757052.1 26251012 1037549 4958952..4960208 1 NC_004431.1 Residues 4 to 417 of 418 are 79.95 pct identical to residues 1 to 414 of 415 from SwissProt.40 : >sp|P06184|PGTA_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PGTA; transport activator 4960208 pgtA 1037549 pgtA Escherichia coli CFT073 transport activator NP_757052.1 4958952 D 199310 CDS NP_757053.1 26251013 1037548 complement(4961189..4961833) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z1645; hypothetical protein 4961833 1037548 c5205 Escherichia coli CFT073 hypothetical protein NP_757053.1 4961189 R 199310 CDS NP_757054.1 26251014 1037547 complement(4961854..4962162) 1 NC_004431.1 Residues 14 to 102 of 102 are 95.50 pct identical to residues 1 to 89 of 89 from GenPept.129 : >dbj|BAB34811.1| (AP002554) transcriptional regulator [Escherichia coli O157:H7]; hypothetical protein 4962162 1037547 c5206 Escherichia coli CFT073 hypothetical protein NP_757054.1 4961854 R 199310 CDS NP_757055.1 26251015 1037546 complement(4962202..4962357) 1 NC_004431.1 Residues 19 to 51 of 51 are 100.00 pct identical to residues 180 to 212 of 212 from GenPept.129 : >gb|AAG55759.1|AE005312_5 (AE005312) unknown [Escherichia coli O157:H7 EDL933]; hypothetical protein 4962357 1037546 c5207 Escherichia coli CFT073 hypothetical protein NP_757055.1 4962202 R 199310 CDS NP_757056.1 26251016 1037545 complement(4962284..4962847) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z1644; hypothetical protein 4962847 1037545 c5208 Escherichia coli CFT073 hypothetical protein NP_757056.1 4962284 R 199310 CDS NP_757057.1 26251017 1037544 complement(4962832..4964064) 1 NC_004431.1 Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z1643; hypothetical protein 4964064 1037544 c5209 Escherichia coli CFT073 hypothetical protein NP_757057.1 4962832 R 199310 CDS NP_757058.1 26251018 1037543 complement(4964200..4964853) 1 NC_004431.1 hypothetical protein 4964853 1037543 c5210 Escherichia coli CFT073 hypothetical protein NP_757058.1 4964200 R 199310 CDS NP_757059.1 26251019 1037542 complement(4965038..4966498) 1 NC_004431.1 hypothetical protein 4966498 1037542 c5211 Escherichia coli CFT073 hypothetical protein NP_757059.1 4965038 R 199310 CDS NP_757060.1 26251020 1037541 4965775..4965957 1 NC_004431.1 hypothetical protein 4965957 1037541 c5212 Escherichia coli CFT073 hypothetical protein NP_757060.1 4965775 D 199310 CDS NP_757061.1 26251021 1037540 complement(4966657..4967547) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z3297; transposase IS629 4967547 1037540 c5213 Escherichia coli CFT073 transposase IS629 NP_757061.1 4966657 R 199310 CDS NP_757062.1 26251022 1037539 complement(4967544..4967870) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 4967870 1037539 c5214 Escherichia coli CFT073 hypothetical protein NP_757062.1 4967544 R 199310 CDS NP_757063.1 26251023 1037538 complement(4967922..4969685) 1 NC_004431.1 Residues 5 to 587 of 587 are 96.39 pct identical to residues 1 to 583 of 774 from GenPept.129 : >gb|AAK00457.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 4969685 1037538 c5215 Escherichia coli CFT073 hypothetical protein NP_757063.1 4967922 R 199310 CDS NP_757064.1 26251024 1037536 complement(4970125..4971387) 1 NC_004431.1 Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 4971387 1037536 c5216 Escherichia coli CFT073 prophage P4 integrase NP_757064.1 4970125 R 199310 CDS NP_757065.1 26251025 1037533 complement(4971767..4972366) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4135; Escherichia coli O157:H7 ortholog: z5740; transcriptional regulator 4972366 yjdC 1037533 yjdC Escherichia coli CFT073 transcriptional regulator NP_757065.1 4971767 R 199310 CDS NP_757066.1 26251026 1037532 complement(4972379..4974076) 1 NC_004431.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4974076 dipZ 1037532 dipZ Escherichia coli CFT073 thiol:disulfide interchange protein NP_757066.1 4972379 R 199310 CDS NP_757067.2 161486019 1037531 complement(4974052..4974390) 1 NC_004431.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4974390 cutA 1037531 cutA Escherichia coli CFT073 divalent-cation tolerance protein CutA NP_757067.2 4974052 R 199310 CDS NP_757068.1 26251028 1037530 complement(4974506..4975807) 1 NC_004431.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4975807 dcuA 1037530 dcuA Escherichia coli CFT073 anaerobic C4-dicarboxylate transporter NP_757068.1 4974506 R 199310 CDS NP_757069.1 26251029 1037529 4975907..4977358 1 NC_004431.1 Residues 349 to 483 of 483 are 100.00 pct identical to residues 1 to 135 of 135 from GenPept.129 : >emb|CAA26174.1| (X02307) URF 4 [Escherichia coli]; hypothetical protein 4977358 1037529 c5221 Escherichia coli CFT073 hypothetical protein NP_757069.1 4975907 D 199310 CDS NP_757070.1 26251030 1037528 complement(4975925..4977406) 1 NC_004431.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4977406 aspA 1037528 aspA Escherichia coli CFT073 aspartate ammonia-lyase NP_757070.1 4975925 R 199310 CDS NP_757071.1 26251031 1037526 4977698..4978174 1 NC_004431.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 4978174 fxsA 1037526 fxsA Escherichia coli CFT073 FxsA NP_757071.1 4977698 D 199310 CDS NP_757072.2 161486018 1037525 complement(4978190..4979446) 1 NC_004431.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 4979446 yjeH 1037525 yjeH Escherichia coli CFT073 hypothetical protein NP_757072.2 4978190 R 199310 CDS NP_757073.1 26251033 1037524 complement(4979719..4980036) 1 NC_004431.1 hypothetical protein 4980036 1037524 c5225 Escherichia coli CFT073 hypothetical protein NP_757073.1 4979719 R 199310 CDS NP_757074.1 26251034 1037523 4979722..4980015 1 NC_004431.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4980015 groES 1037523 groES Escherichia coli CFT073 co-chaperonin GroES NP_757074.1 4979722 D 199310 CDS NP_757075.1 26251035 1037522 4980059..4981705 1 NC_004431.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4981705 groEL 1037522 groEL Escherichia coli CFT073 molecular chaperone GroEL NP_757075.1 4980059 D 199310 CDS NP_757076.1 26251036 1037521 4981810..4982196 1 NC_004431.1 Escherichia coli K-12 ortholog: b4144; Escherichia coli O157:H7 ortholog: z5749; hypothetical protein 4982196 yjeI 1037521 yjeI Escherichia coli CFT073 hypothetical protein NP_757076.1 4981810 D 199310 CDS NP_757077.1 26251037 1037520 complement(4981882..4982286) 1 NC_004431.1 hypothetical protein 4982286 1037520 c5229 Escherichia coli CFT073 hypothetical protein NP_757077.1 4981882 R 199310 CDS NP_757078.1 26251038 1037519 complement(4982246..4983115) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4145; Escherichia coli O157:H7 ortholog: z5750; hypothetical protein 4983115 yjeJ 1037519 yjeJ Escherichia coli CFT073 hypothetical protein NP_757078.1 4982246 R 199310 CDS NP_757079.1 26251039 1037518 complement(4983350..4984378) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4146; Escherichia coli O157:H7 ortholog: z5751; hypothetical protein 4984378 yjeK 1037518 yjeK Escherichia coli CFT073 hypothetical protein NP_757079.1 4983350 R 199310 CDS NP_757080.1 26251040 1037517 4984420..4984986 1 NC_004431.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4984986 efp 1037517 efp Escherichia coli CFT073 elongation factor P NP_757080.1 4984420 D 199310 CDS NP_757081.1 26251041 1037516 complement(4984468..4985022) 1 NC_004431.1 hypothetical protein 4985022 1037516 c5233 Escherichia coli CFT073 hypothetical protein NP_757081.1 4984468 R 199310 CDS NP_757082.1 26251042 1037515 4985038..4985163 1 NC_004431.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4985163 ecnA 1037515 ecnA Escherichia coli CFT073 entericidin A NP_757082.1 4985038 D 199310 CDS NP_757083.1 26251043 1037514 4985274..4985420 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5754; entericidin B 4985420 ecnB 1037514 ecnB Escherichia coli CFT073 entericidin B NP_757083.1 4985274 D 199310 CDS NP_757084.1 26251044 1037513 4985446..4985913 1 NC_004431.1 Escherichia coli K-12 ortholog: b4148; Escherichia coli O157:H7 ortholog: z5755; SugE protein 4985913 sugE 1037513 sugE Escherichia coli CFT073 SugE protein NP_757084.1 4985446 D 199310 CDS NP_757085.1 26251045 1037512 complement(4985910..4986443) 1 NC_004431.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4986443 blc 1037512 blc Escherichia coli CFT073 outer membrane lipoprotein Blc NP_757085.1 4985910 R 199310 CDS NP_757086.2 161486017 1037511 complement(4986532..4987665) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4150; Escherichia coli O157:H7 ortholog: z5757; beta-lactamase 4987665 ampC 1037511 ampC Escherichia coli CFT073 beta-lactamase NP_757086.2 4986532 R 199310 CDS NP_757087.1 26251047 1037510 complement(4987728..4988117) 1 NC_004431.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4988117 frdD 1037510 frdD Escherichia coli CFT073 fumarate reductase subunit D NP_757087.1 4987728 R 199310 CDS NP_757088.1 26251048 1037509 complement(4988098..4988493) 1 NC_004431.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4988493 frdC 1037509 frdC Escherichia coli CFT073 fumarate reductase subunit C NP_757088.1 4988098 R 199310 CDS NP_757089.1 26251049 1037508 complement(4988504..4989238) 1 NC_004431.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4989238 frdB 1037508 frdB Escherichia coli CFT073 fumarate reductase iron-sulfur subunit NP_757089.1 4988504 R 199310 CDS NP_757090.1 26251050 1037507 complement(4989231..4991039) 1 NC_004431.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4991039 frdA 1037507 frdA Escherichia coli CFT073 fumarate reductase flavoprotein subunit NP_757090.1 4989231 R 199310 CDS NP_757091.2 161486016 1037506 4991364..4992341 1 NC_004431.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4992341 yjeA 1037506 yjeA Escherichia coli CFT073 lysyl-tRNA synthetase NP_757091.2 4991364 D 199310 CDS NP_757092.1 26251052 1037505 4992518..4994062 1 NC_004431.1 Escherichia coli K-12 ortholog: b4156; Escherichia coli O157:H7 ortholog: z5764; transporter YjeM 4994062 yjeM 1037505 yjeM Escherichia coli CFT073 transporter YjeM NP_757092.1 4992518 D 199310 CDS NP_757093.1 26251053 1037504 complement(4994213..4997536) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4159; Escherichia coli O157:H7 ortholog: z5765; hypothetical protein 4997536 yjeP 1037504 yjeP Escherichia coli CFT073 hypothetical protein NP_757093.1 4994213 R 199310 CDS NP_757094.1 26251054 1037503 4997456..4998481 1 NC_004431.1 hypothetical protein 4998481 1037503 c5246 Escherichia coli CFT073 hypothetical protein NP_757094.1 4997456 D 199310 CDS NP_757095.1 26251055 1037502 complement(4997558..4998526) 1 NC_004431.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4998526 psd 1037502 psd Escherichia coli CFT073 phosphatidylserine decarboxylase NP_757095.1 4997558 R 199310 CDS NP_757096.2 161486015 1037501 complement(4998623..4999675) 1 NC_004431.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4999675 yjeQ 1037501 yjeQ Escherichia coli CFT073 ribosome-associated GTPase NP_757096.2 4998623 R 199310 CDS NP_757097.2 161486014 1037500 4999770..5000315 1 NC_004431.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 5000315 yjeR 1037500 yjeR Escherichia coli CFT073 oligoribonuclease NP_757097.2 4999770 D 199310 CDS NP_757098.1 26251058 1037495 complement(5001094..5002278) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4166; Escherichia coli O157:H7 ortholog: z5773; electron transport protein yjeS 5002278 yjeS 1037495 yjeS Escherichia coli CFT073 electron transport protein yjeS NP_757098.1 5001094 R 199310 CDS NP_757099.1 26251059 1037494 5002211..5003779 1 NC_004431.1 Escherichia coli K-12 ortholog: b4167; Escherichia coli O157:H7 ortholog: z5774; hypothetical protein 5003779 yjeF 1037494 yjeF Escherichia coli CFT073 hypothetical protein NP_757099.1 5002211 D 199310 CDS NP_757100.1 26251060 1037493 5003751..5004212 1 NC_004431.1 possibly involved in cell wall synthesis; ATPase 5004212 yjeE 1037493 yjeE Escherichia coli CFT073 ATPase NP_757100.1 5003751 D 199310 CDS NP_757101.1 26251061 1037492 5004216..5005562 1 NC_004431.1 Escherichia coli K-12 ortholog: b4169; Escherichia coli O157:H7 ortholog: z5776; N-acetylmuramoyl-L-alanine amidase 5005562 amiB 1037492 amiB Escherichia coli CFT073 N-acetylmuramoyl-L-alanine amidase NP_757101.1 5004216 D 199310 CDS NP_757102.1 26251062 1037491 5005569..5007419 1 NC_004431.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5007419 mutL 1037491 mutL Escherichia coli CFT073 DNA mismatch repair protein NP_757102.1 5005569 D 199310 CDS NP_757103.1 26251063 1037490 5007412..5008362 1 NC_004431.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5008362 miaA 1037490 miaA Escherichia coli CFT073 tRNA delta(2)-isopentenylpyrophosphate transferase NP_757103.1 5007412 D 199310 CDS NP_757104.1 26251064 1037487 5008448..5008756 1 NC_004431.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5008756 hfq 1037487 hfq Escherichia coli CFT073 RNA-binding protein Hfq NP_757104.1 5008448 D 199310 CDS NP_757105.1 26251065 1037486 5008832..5010112 1 NC_004431.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5010112 hflX 1037486 hflX Escherichia coli CFT073 GTPase HflX NP_757105.1 5008832 D 199310 CDS NP_757106.1 26251066 1037485 5010198..5011457 1 NC_004431.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5011457 hflK 1037485 hflK Escherichia coli CFT073 FtsH protease regulator HflK NP_757106.1 5010198 D 199310 CDS NP_757107.1 26251067 1037484 5011460..5012464 1 NC_004431.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5012464 hflC 1037484 hflC Escherichia coli CFT073 FtsH protease regulator HflC NP_757107.1 5011460 D 199310 CDS NP_757108.1 26251068 1037483 5012546..5012743 1 NC_004431.1 Escherichia coli K-12 ortholog: b4176; Escherichia coli O157:H7 ortholog: z5783; hypothetical protein 5012743 yjeT 1037483 yjeT Escherichia coli CFT073 hypothetical protein NP_757108.1 5012546 D 199310 CDS NP_757109.1 26251069 1037482 5012847..5014145 1 NC_004431.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5014145 purA 1037482 purA Escherichia coli CFT073 adenylosuccinate synthetase NP_757109.1 5012847 D 199310 CDS NP_757110.1 26251070 1037481 5014350..5014775 1 NC_004431.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5014775 yjeB 1037481 yjeB Escherichia coli CFT073 transcriptional repressor NsrR NP_757110.1 5014350 D 199310 CDS NP_757111.2 161486013 1037480 5014814..5017255 1 NC_004431.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5017255 vacB 1037480 vacB Escherichia coli CFT073 exoribonuclease R NP_757111.2 5014814 D 199310 CDS NP_757112.1 26251072 1037479 5017346..5018077 1 NC_004431.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5018077 yjfH 1037479 yjfH Escherichia coli CFT073 23S rRNA (guanosine-2'-O-)-methyltransferase NP_757112.1 5017346 D 199310 CDS NP_757113.1 26251073 1037478 5018204..5018605 1 NC_004431.1 Escherichia coli K-12 ortholog: b4181; Escherichia coli O157:H7 ortholog: z5788; hypothetical protein 5018605 yjfI 1037478 yjfI Escherichia coli CFT073 hypothetical protein NP_757113.1 5018204 D 199310 CDS NP_757114.1 26251074 1037477 5018624..5019322 1 NC_004431.1 Escherichia coli K-12 ortholog: b4182; Escherichia coli O157:H7 ortholog: z5789; hypothetical protein 5019322 yjfJ 1037477 yjfJ Escherichia coli CFT073 hypothetical protein NP_757114.1 5018624 D 199310 CDS NP_757115.1 26251075 1037476 5019372..5020031 1 NC_004431.1 Escherichia coli K-12 ortholog: b4183; Escherichia coli O157:H7 ortholog: z5790; hypothetical protein 5020031 yjfK 1037476 yjfK Escherichia coli CFT073 hypothetical protein NP_757115.1 5019372 D 199310 CDS NP_757116.1 26251076 1037475 5020049..5020438 1 NC_004431.1 Escherichia coli K-12 ortholog: b4184; Escherichia coli O157:H7 ortholog: z5791; hypothetical protein 5020438 yjfL 1037475 yjfL Escherichia coli CFT073 hypothetical protein NP_757116.1 5020049 D 199310 CDS NP_757117.1 26251077 1037472 5020279..5020446 1 NC_004431.1 Residues 23 to 55 of 55 are 90.90 pct identical to residues 100 to 132 of 132 from GenPept.129 : >gb|AAG59380.1|AE005651_9 (AE005651) yjfL gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 5020446 1037472 c5269 Escherichia coli CFT073 hypothetical protein NP_757117.1 5020279 D 199310 CDS NP_757118.1 26251078 1037471 complement(5020333..5020500) 1 NC_004431.1 hypothetical protein 5020500 1037471 c5270 Escherichia coli CFT073 hypothetical protein NP_757118.1 5020333 R 199310 CDS NP_757119.1 26251079 1037470 complement(5020365..5020517) 1 NC_004431.1 hypothetical protein 5020517 1037470 c5271 Escherichia coli CFT073 hypothetical protein NP_757119.1 5020365 R 199310 CDS NP_757120.1 26251080 1037469 5020579..5021094 1 NC_004431.1 Escherichia coli K-12 ortholog: b4185; Escherichia coli O157:H7 ortholog: z5792; hypothetical protein 5021094 yjfM 1037469 yjfM Escherichia coli CFT073 hypothetical protein NP_757120.1 5020579 D 199310 CDS NP_757121.1 26251081 1037468 5021339..5022259 1 NC_004431.1 Escherichia coli K-12 ortholog: b4186; Escherichia coli O157:H7 ortholog: z5793; hypothetical protein 5022259 yjfC 1037468 yjfC Escherichia coli CFT073 hypothetical protein NP_757121.1 5021339 D 199310 CDS NP_757122.1 26251082 1037466 5022325..5023968 1 NC_004431.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5023968 aidB 1037466 aidB Escherichia coli CFT073 isovaleryl CoA dehydrogenase NP_757122.1 5022325 D 199310 CDS NP_757123.1 26251083 1037465 complement(5024085..5024387) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4188; Escherichia coli O157:H7 ortholog: z5795; hypothetical protein 5024387 yjfN 1037465 yjfN Escherichia coli CFT073 hypothetical protein NP_757123.1 5024085 R 199310 CDS NP_757124.2 161486012 1037464 complement(5024509..5024838) 1 NC_004431.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 5024838 yjfO 1037464 yjfO Escherichia coli CFT073 biofilm stress and motility protein A NP_757124.2 5024509 R 199310 CDS NP_757125.1 26251085 1037463 5025020..5025769 1 NC_004431.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5025769 yjfP 1037463 yjfP Escherichia coli CFT073 esterase NP_757125.1 5025020 D 199310 CDS NP_757126.1 26251086 1037462 complement(5025766..5026521) 1 NC_004431.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 5026521 yjfQ 1037462 yjfQ Escherichia coli CFT073 transcriptional repressor UlaR NP_757126.1 5025766 R 199310 CDS NP_757127.1 26251087 1037461 complement(5026629..5027699) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4192; Escherichia coli O157:H7 ortholog: z5801; L-ascorbate 6-phosphate lactonase 5027699 yjfR 1037461 yjfR Escherichia coli CFT073 L-ascorbate 6-phosphate lactonase NP_757127.1 5026629 R 199310 CDS NP_757128.1 26251088 1037460 5028048..5029445 1 NC_004431.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5029445 ulaA 1037460 ulaA Escherichia coli CFT073 PTS system ascorbate-specific transporter subunit IIC NP_757128.1 5028048 D 199310 CDS NP_757129.1 26251089 1037459 complement(5029442..5029777) 1 NC_004431.1 hypothetical protein 5029777 1037459 c5282 Escherichia coli CFT073 hypothetical protein NP_757129.1 5029442 R 199310 CDS NP_757130.1 26251090 1037458 5029455..5029766 1 NC_004431.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5029766 sgaB 1037458 sgaB Escherichia coli CFT073 PTS system L-ascorbate-specific transporter subunit IIB NP_757130.1 5029455 D 199310 CDS NP_757131.1 26251091 1037457 5029776..5030240 1 NC_004431.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5030240 ptxA 1037457 ptxA Escherichia coli CFT073 PTS system L-ascorbate-specific transporter subunit IIA NP_757131.1 5029776 D 199310 CDS NP_757132.2 161486011 1037456 5030254..5030904 1 NC_004431.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5030904 ulaD 1037456 ulaD Escherichia coli CFT073 3-keto-L-gulonate-6-phosphate decarboxylase NP_757132.2 5030254 D 199310 CDS NP_757133.1 26251093 1037455 complement(5030260..5030928) 1 NC_004431.1 hypothetical protein 5030928 1037455 c5286 Escherichia coli CFT073 hypothetical protein NP_757133.1 5030260 R 199310 CDS NP_757134.1 26251094 1037453 5030914..5031768 1 NC_004431.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5031768 sgaU 1037453 sgaU Escherichia coli CFT073 L-xylulose 5-phosphate 3-epimerase NP_757134.1 5030914 D 199310 CDS NP_757135.2 161486010 1037452 5031768..5032454 1 NC_004431.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5032454 sgaE 1037452 sgaE Escherichia coli CFT073 L-ribulose-5-phosphate 4-epimerase NP_757135.2 5031768 D 199310 CDS NP_757136.1 26251096 1037450 complement(5032583..5032858) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4199; Escherichia coli O157:H7 ortholog: z5808; hypothetical protein 5032858 yjfY 1037450 yjfY Escherichia coli CFT073 hypothetical protein NP_757136.1 5032583 R 199310 CDS NP_757137.1 26251097 1037448 complement(5033084..5033467) 1 NC_004431.1 hypothetical protein 5033467 1037448 c5290 Escherichia coli CFT073 hypothetical protein NP_757137.1 5033084 R 199310 CDS NP_757138.1 26251098 1037446 5033186..5033581 1 NC_004431.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5033581 rpsF 1037446 rpsF Escherichia coli CFT073 30S ribosomal protein S6 NP_757138.1 5033186 D 199310 CDS NP_757139.1 26251099 1037445 5033907..5034134 1 NC_004431.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5034134 rpsR 1037445 rpsR Escherichia coli CFT073 30S ribosomal protein S18 NP_757139.1 5033907 D 199310 CDS NP_757140.1 26251100 1037444 complement(5034149..5034637) 1 NC_004431.1 hypothetical protein 5034637 1037444 c5293 Escherichia coli CFT073 hypothetical protein NP_757140.1 5034149 R 199310 CDS NP_757141.1 26251101 1037443 5034176..5034625 1 NC_004431.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5034625 rplI 1037443 rplI Escherichia coli CFT073 50S ribosomal protein L9 NP_757141.1 5034176 D 199310 CDS NP_757142.1 26251102 1037442 5035027..5035518 1 NC_004431.1 hypothetical protein 5035518 1037442 c5295 Escherichia coli CFT073 hypothetical protein NP_757142.1 5035027 D 199310 CDS NP_757143.1 26251103 1037441 5035521..5036108 1 NC_004431.1 hypothetical protein 5036108 1037441 c5296 Escherichia coli CFT073 hypothetical protein NP_757143.1 5035521 D 199310 CDS NP_757144.1 26251104 1037436 5036179..5036790 1 NC_004431.1 Residues 6 to 200 of 203 are 26.49 pct identical to residues 235 to 430 of 435 from GenPept.129 : >gb|AAK24734.1| (AE005942) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 5036790 1037436 c5297 Escherichia coli CFT073 hypothetical protein NP_757144.1 5036179 D 199310 CDS NP_757145.1 26251105 1037433 complement(5036933..5038210) 1 NC_004431.1 Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter 5038210 1037433 c5298 Escherichia coli CFT073 hexuronate transporter NP_757145.1 5036933 R 199310 CDS NP_757146.1 26251106 1037432 complement(5038303..5040375) 1 NC_004431.1 Residues 29 to 688 of 690 are 35.69 pct identical to residues 5 to 663 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, [Thermotoga maritima]; oxidoreductase 5040375 1037432 c5299 Escherichia coli CFT073 oxidoreductase NP_757146.1 5038303 R 199310 CDS NP_757147.1 26251107 1037430 complement(5040372..5041913) 1 NC_004431.1 Residues 3 to 507 of 513 are 46.16 pct identical to residues 4 to 507 of 525 from GenPept.129 : >dbj|BAB07617.1| (AP001520) acetyl-CoA:acetoacetyl-CoA transferase [Bacillus halodurans]; acetyl-CoA:acetoacetyl-CoA transferase 5041913 1037430 c5300 Escherichia coli CFT073 acetyl-CoA:acetoacetyl-CoA transferase NP_757147.1 5040372 R 199310 CDS NP_757148.1 26251108 1037429 complement(5041923..5042699) 1 NC_004431.1 Residues 4 to 255 of 258 are 36.75 pct identical to residues 3 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) dehydratase [Sinorhizobium meliloti]; hypothetical protein 5042699 1037429 c5301 Escherichia coli CFT073 hypothetical protein NP_757148.1 5041923 R 199310 CDS NP_757149.1 26251109 1037427 complement(5042709..5043551) 1 NC_004431.1 Residues 1 to 268 of 280 are 97.76 pct identical to residues 1 to 268 of 294 from GenPept.129 : >gb|AAL50626.1|AF417476_3 (AF417476) unknown [Shigella flexneri]; hypothetical protein 5043551 1037427 c5302 Escherichia coli CFT073 hypothetical protein NP_757149.1 5042709 R 199310 CDS NP_757150.1 26251110 1037426 complement(5043561..5044352) 1 NC_004431.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 5044352 fabG 1037426 fabG Escherichia coli CFT073 3-ketoacyl-ACP reductase NP_757150.1 5043561 R 199310 CDS NP_757151.1 26251111 1037425 5044493..5045212 1 NC_004431.1 Residues 132 to 239 of 239 are 97.22 pct identical to residues 1 to 108 of 108 from MG1655 : b4205; hypothetical protein 5045212 1037425 c5304 Escherichia coli CFT073 hypothetical protein NP_757151.1 5044493 D 199310 CDS NP_757152.1 26251112 1037424 complement(5045196..5045870) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4206; Escherichia coli O157:H7 ortholog: z5817; hypothetical protein 5045870 ytfB 1037424 ytfB Escherichia coli CFT073 hypothetical protein NP_757152.1 5045196 R 199310 CDS NP_757153.2 161486009 1037423 5046052..5046672 1 NC_004431.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5046672 fklB 1037423 fklB Escherichia coli CFT073 peptidyl-prolyl cis-trans isomerase NP_757153.2 5046052 D 199310 CDS NP_757154.1 26251114 1037421 5046982..5048394 1 NC_004431.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5048394 cycA 1037421 cycA Escherichia coli CFT073 D-alanine/D-serine/glycine permease NP_757154.1 5046982 D 199310 CDS NP_757155.1 26251115 1037420 complement(5048439..5049101) 1 NC_004431.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 5049101 ytfE 1037420 ytfE Escherichia coli CFT073 iron-sulfur cluster repair di-iron protein NP_757155.1 5048439 R 199310 CDS NP_757156.1 26251116 1037419 complement(5049209..5050183) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4210; Escherichia coli O157:H7 ortholog: z5821; hypothetical protein 5050183 ytfF 1037419 ytfF Escherichia coli CFT073 hypothetical protein NP_757156.1 5049209 R 199310 CDS NP_757157.1 26251117 1037418 complement(5050282..5051142) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4211; Escherichia coli O157:H7 ortholog: z5822; hypothetical protein 5051142 ytfG 1037418 ytfG Escherichia coli CFT073 hypothetical protein NP_757157.1 5050282 R 199310 CDS NP_757158.1 26251118 1037417 5051120..5051611 1 NC_004431.1 Escherichia coli K-12 ortholog: b4212; Escherichia coli O157:H7 ortholog: z5823; hypothetical protein 5051611 ytfH 1037417 ytfH Escherichia coli CFT073 hypothetical protein NP_757158.1 5051120 D 199310 CDS NP_757159.1 26251119 1037416 complement(5051740..5051976) 1 NC_004431.1 Residues 1 to 78 of 78 are 97.43 pct identical to residues 570 to 647 of 647 from MG1655 : b4213; hypothetical protein 5051976 1037416 c5312 Escherichia coli CFT073 hypothetical protein NP_757159.1 5051740 R 199310 CDS NP_757160.1 26251120 1037415 5053873..5054613 1 NC_004431.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5054613 cysQ 1037415 cysQ Escherichia coli CFT073 adenosine-3'(2'),5'-bisphosphate nucleotidase NP_757160.1 5053873 D 199310 CDS NP_757161.1 26251121 1037414 complement(5054603..5055160) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4216; Escherichia coli O157:H7 ortholog: z5827; hypothetical protein 5055160 1037414 c5314 Escherichia coli CFT073 hypothetical protein NP_757161.1 5054603 R 199310 CDS NP_757162.1 26251122 1037413 5055419..5055691 1 NC_004431.1 Escherichia coli K-12 ortholog: b4217; Escherichia coli O157:H7 ortholog: z5828; hypothetical protein 5055691 ytfK 1037413 ytfK Escherichia coli CFT073 hypothetical protein NP_757162.1 5055419 D 199310 CDS NP_757163.1 26251123 1037412 complement(5055769..5057112) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4218; Escherichia coli O157:H7 ortholog: z5829; hypothetical protein 5057112 ytfL 1037412 ytfL Escherichia coli CFT073 hypothetical protein NP_757163.1 5055769 R 199310 CDS NP_757164.1 26251124 1037410 complement(5057435..5058139) 1 NC_004431.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 5058139 msrA 1037410 msrA Escherichia coli CFT073 methionine sulfoxide reductase A NP_757164.1 5057435 R 199310 CDS NP_757165.1 26251125 1037409 5058279..5060012 1 NC_004431.1 Escherichia coli K-12 ortholog: b4220; Escherichia coli O157:H7 ortholog: z5831; hypothetical protein 5060012 ytfM 1037409 ytfM Escherichia coli CFT073 hypothetical protein NP_757165.1 5058279 D 199310 CDS NP_757166.1 26251126 1037407 5060009..5063788 1 NC_004431.1 Escherichia coli K-12 ortholog: b4221; Escherichia coli O157:H7 ortholog: z5832; hypothetical protein 5063788 ytfN 1037407 ytfN Escherichia coli CFT073 hypothetical protein NP_757166.1 5060009 D 199310 CDS NP_757167.1 26251127 1037404 5063791..5064132 1 NC_004431.1 Escherichia coli K-12 ortholog: b4222; Escherichia coli O157:H7 ortholog: z5833; hypothetical protein 5064132 ytfP 1037404 ytfP Escherichia coli CFT073 hypothetical protein NP_757167.1 5063791 D 199310 CDS NP_757168.1 26251128 1037403 5064282..5065754 1 NC_004431.1 Residues 34 to 117 of 490 are 35.71 pct identical to residues 237 to 320 of 327 from MG1655 : b0644; hypothetical protein 5065754 1037403 c5321 Escherichia coli CFT073 hypothetical protein NP_757168.1 5064282 D 199310 CDS NP_757169.1 26251129 1037402 complement(5065817..5065957) 1 NC_004431.1 hypothetical protein 5065957 1037402 c5322 Escherichia coli CFT073 hypothetical protein NP_757169.1 5065817 R 199310 CDS NP_757170.1 26251130 1037400 complement(5066168..5066698) 1 NC_004431.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 5066698 ppa 1037400 ppa Escherichia coli CFT073 inorganic pyrophosphatase NP_757170.1 5066168 R 199310 CDS NP_757171.1 26251131 1037399 complement(5066710..5066835) 1 NC_004431.1 hypothetical protein 5066835 1037399 c5324 Escherichia coli CFT073 hypothetical protein NP_757171.1 5066710 R 199310 CDS NP_757172.1 26251132 1037398 5067008..5067964 1 NC_004431.1 Escherichia coli K-12 ortholog: b4227; Escherichia coli O157:H7 ortholog: z5838; ABC transporter periplasmic-binding protein 5067964 ytfQ 1037398 ytfQ Escherichia coli CFT073 ABC transporter periplasmic-binding protein NP_757172.1 5067008 D 199310 CDS NP_757173.1 26251133 1037394 5068104..5069606 1 NC_004431.1 Escherichia coli K-12 ortholog: b4228; Escherichia coli O157:H7 ortholog: z5839; ABC transporter ATP-binding protein 5069606 ytfR 1037394 ytfR Escherichia coli CFT073 ABC transporter ATP-binding protein NP_757173.1 5068104 D 199310 CDS NP_757174.1 26251134 1037393 5069596..5070642 1 NC_004431.1 Escherichia coli K-12 ortholog: b4230; Escherichia coli O157:H7 ortholog: z5840; ABC transporter permease 5070642 ytfT 1037393 ytfT Escherichia coli CFT073 ABC transporter permease NP_757174.1 5069596 D 199310 CDS NP_757175.1 26251135 1037391 5070629..5071624 1 NC_004431.1 membrane component of a sugar ABC transporter system; ABC transporter permease 5071624 yjfF 1037391 yjfF Escherichia coli CFT073 ABC transporter permease NP_757175.1 5070629 D 199310 CDS NP_757176.1 26251136 1037390 complement(5071657..5072718) 1 NC_004431.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 5072718 fbp 1037390 fbp Escherichia coli CFT073 fructose-1,6-bisphosphatase NP_757176.1 5071657 R 199310 CDS NP_757177.1 26251137 1037385 5072718..5072849 1 NC_004431.1 hypothetical protein 5072849 1037385 c5330 Escherichia coli CFT073 hypothetical protein NP_757177.1 5072718 D 199310 CDS NP_757178.1 26251138 1037383 5072831..5074204 1 NC_004431.1 Escherichia coli K-12 ortholog: b4233; Escherichia coli O157:H7 ortholog: z5843; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat e ligase 5074204 yjfG 1037383 yjfG Escherichia coli CFT073 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat e ligase NP_757178.1 5072831 D 199310 CDS NP_757179.1 26251139 1037382 complement(5074362..5074913) 1 NC_004431.1 X96 protein; Escherichia coli K-12 ortholog: b4234; Escherichia coli O157:H7 ortholog: z5844; hypothetical protein 5074913 yjgA 1037382 yjgA Escherichia coli CFT073 hypothetical protein NP_757179.1 5074362 R 199310 CDS NP_757180.1 26251140 1037380 5075007..5076359 1 NC_004431.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5076359 pmbA 1037380 pmbA Escherichia coli CFT073 peptidase PmbA NP_757180.1 5075007 D 199310 CDS NP_757181.1 26251141 1037379 complement(5076398..5076808) 1 NC_004431.1 hypothetical protein 5076808 1037379 c5334 Escherichia coli CFT073 hypothetical protein NP_757181.1 5076398 R 199310 CDS NP_757182.1 26251142 1037377 5076543..5076929 1 NC_004431.1 Cytochrome b-562; Escherichia coli K-12 ortholog: b4236; Escherichia coli O157:H7 ortholog: z5846; soluble cytochrome b562 5076929 cybC 1037377 cybC Escherichia coli CFT073 soluble cytochrome b562 NP_757182.1 5076543 D 199310 CDS NP_757183.1 26251143 1037376 complement(5076974..5077438) 1 NC_004431.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 5077438 nrdG 1037376 nrdG Escherichia coli CFT073 anaerobic ribonucleotide reductase-activating protein NP_757183.1 5076974 R 199310 CDS NP_757184.1 26251144 1037373 complement(5077596..5079734) 1 NC_004431.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 5079734 nrdD 1037373 nrdD Escherichia coli CFT073 anaerobic ribonucleoside triphosphate reductase NP_757184.1 5077596 R 199310 CDS NP_757185.1 26251145 1037372 complement(5080128..5081783) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4239; Escherichia coli O157:H7 ortholog: z5849; trehalose-6-phosphate hydrolase 5081783 treC 1037372 treC Escherichia coli CFT073 trehalose-6-phosphate hydrolase NP_757185.1 5080128 R 199310 CDS NP_757186.1 26251146 1037371 complement(5081833..5083254) 1 NC_004431.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 5083254 treB 1037371 treB Escherichia coli CFT073 PTS system trehalose(maltose)-specific transporter subunits IIBC NP_757186.1 5081833 R 199310 CDS NP_757187.1 26251147 1037370 complement(5083373..5084320) 1 NC_004431.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 5084320 treR 1037370 treR Escherichia coli CFT073 trehalose repressor NP_757187.1 5083373 R 199310 CDS NP_757188.1 26251148 1037368 5084699..5087395 1 NC_004431.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5087395 mgtA 1037368 mgtA Escherichia coli CFT073 magnesium-transporting ATPase MgtA NP_757188.1 5084699 D 199310 CDS NP_757189.1 26251149 1037367 complement(5087601..5088059) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4243; Escherichia coli O157:H7 ortholog: z5854; hypothetical protein 5088059 yjgF 1037367 yjgF Escherichia coli CFT073 hypothetical protein NP_757189.1 5087601 R 199310 CDS NP_757190.1 26251150 1037366 5087694..5088158 1 NC_004431.1 hypothetical protein 5088158 1037366 c5343 Escherichia coli CFT073 hypothetical protein NP_757190.1 5087694 D 199310 CDS NP_757191.1 26251151 1037365 complement(5088060..5088521) 1 NC_004431.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 5088521 pyrI 1037365 pyrI Escherichia coli CFT073 aspartate carbamoyltransferase NP_757191.1 5088060 R 199310 CDS NP_757192.1 26251152 1037364 complement(5088534..5089469) 1 NC_004431.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 5089469 pyrB 1037364 pyrB Escherichia coli CFT073 aspartate carbamoyltransferase NP_757192.1 5088534 R 199310 CDS NP_757193.1 26251153 1037363 complement(5089473..5089607) 1 NC_004431.1 Attenuator; Escherichia coli K-12 ortholog: b4246; pyrBI operon leader peptide 5089607 pyrL 1037363 pyrL Escherichia coli CFT073 pyrBI operon leader peptide NP_757193.1 5089473 R 199310 CDS NP_757194.1 26251154 1037362 complement(5089697..5090251) 1 NC_004431.1 Residues 23 to 184 of 184 are 87.03 pct identical to residues 1 to 162 of 162 from GenPept.129 : >gb|AAL23282.1| (AE008909) arginine repressor [Salmonella typhimurium LT2]; hypothetical protein 5090251 1037362 c5346 Escherichia coli CFT073 hypothetical protein NP_757194.1 5089697 R 199310 CDS NP_757195.1 26251155 1037361 complement(5090301..5091749) 1 NC_004431.1 Residues 16 to 482 of 482 are 89.93 pct identical to residues 1 to 467 of 467 from GenPept.129 : >emb|CAD06924.1| (AL627283) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 5091749 1037361 c5347 Escherichia coli CFT073 hypothetical protein NP_757195.1 5090301 R 199310 CDS NP_757196.2 161486008 1037360 complement(5091761..5092765) 1 NC_004431.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 5092765 1037360 c5348 Escherichia coli CFT073 ornithine carbamoyltransferase NP_757196.2 5091761 R 199310 CDS NP_757197.1 26251157 1037359 complement(5092789..5093721) 1 NC_004431.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 5093721 1037359 c5349 Escherichia coli CFT073 carbamate kinase NP_757197.1 5092789 R 199310 CDS NP_757198.1 26251158 1037358 complement(5093732..5094955) 1 NC_004431.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 5094955 1037358 c5350 Escherichia coli CFT073 arginine deiminase NP_757198.1 5093732 R 199310 CDS NP_757199.1 26251159 1037357 complement(5095040..5095174) 1 NC_004431.1 hypothetical protein 5095174 1037357 c5351 Escherichia coli CFT073 hypothetical protein NP_757199.1 5095040 R 199310 CDS NP_757200.1 26251160 1037356 5095630..5096082 1 NC_004431.1 Escherichia coli K-12 ortholog: b4252; Escherichia coli O157:H7 ortholog: z5864; hypothetical protein 5096082 yjgK 1037356 yjgK Escherichia coli CFT073 hypothetical protein NP_757200.1 5095630 D 199310 CDS NP_757201.1 26251161 1037355 complement(5096127..5097131) 1 NC_004431.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F 5097131 argI 1037355 argI Escherichia coli CFT073 ornithine carbamoyltransferase subunit F NP_757201.1 5096127 R 199310 CDS NP_757202.1 26251162 1037354 5097293..5097709 1 NC_004431.1 Escherichia coli K-12 ortholog: b4255; Escherichia coli O157:H7 ortholog: z5867; hypothetical protein 5097709 yjgD 1037354 yjgD Escherichia coli CFT073 hypothetical protein NP_757202.1 5097293 D 199310 CDS NP_757203.1 26251163 1037353 complement(5097887..5098408) 1 NC_004431.1 Residues 7 to 173 of 173 are 91.61 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P39337|YJGM_ECOLI HYPOTHETICAL 18.6 KDA PROTEIN IN ARGI-VALS INTERGENIC REGION; hypothetical protein 5098408 1037353 c5355 Escherichia coli CFT073 hypothetical protein NP_757203.1 5097887 R 199310 CDS NP_757204.1 26251164 1037351 5098583..5099113 1 NC_004431.1 Residues 1 to 144 of 176 are 64.58 pct identical to residues 1 to 144 of 395 from GenPept.129 : >gb|AAL23293.1| (AE008910) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5099113 1037351 c5356 Escherichia coli CFT073 hypothetical protein NP_757204.1 5098583 D 199310 CDS NP_757205.1 26251165 1037347 5099082..5099771 1 NC_004431.1 Residues 4 to 229 of 229 are 37.44 pct identical to residues 167 to 393 of 393 from MG1655 : b4257; hypothetical protein 5099771 1037347 c5357 Escherichia coli CFT073 hypothetical protein NP_757205.1 5099082 D 199310 CDS NP_757206.1 26251166 1037346 complement(5099818..5102673) 1 NC_004431.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 5102673 valS 1037346 valS Escherichia coli CFT073 valyl-tRNA synthetase NP_757206.1 5099818 R 199310 CDS NP_757207.1 26251167 1037337 complement(5102673..5103116) 1 NC_004431.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 5103116 holC 1037337 holC Escherichia coli CFT073 DNA polymerase III subunit chi NP_757207.1 5102673 R 199310 CDS NP_757208.1 26251168 1037328 complement(5103374..5104885) 1 NC_004431.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 5104885 pepA 1037328 pepA Escherichia coli CFT073 leucyl aminopeptidase NP_757208.1 5103374 R 199310 CDS NP_757209.1 26251169 1037324 complement(5105110..5105238) 1 NC_004431.1 hypothetical protein 5105238 1037324 c5361 Escherichia coli CFT073 hypothetical protein NP_757209.1 5105110 R 199310 CDS NP_757210.1 26251170 1037320 5105152..5106252 1 NC_004431.1 Escherichia coli K-12 ortholog: b4261; Escherichia coli O157:H7 ortholog: z5873; hypothetical protein 5106252 yjgP 1037320 yjgP Escherichia coli CFT073 hypothetical protein NP_757210.1 5105152 D 199310 CDS NP_757211.1 26251171 1037318 5106249..5107334 1 NC_004431.1 Escherichia coli K-12 ortholog: b4262; Escherichia coli O157:H7 ortholog: z5874; hypothetical protein 5107334 yjgQ 1037318 yjgQ Escherichia coli CFT073 hypothetical protein NP_757211.1 5106249 D 199310 CDS NP_757212.1 26251172 1037316 complement(5107495..5108997) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4263; Escherichia coli O157:H7 ortholog: z5875; hypothetical protein 5108997 yjgR 1037316 yjgR Escherichia coli CFT073 hypothetical protein NP_757212.1 5107495 R 199310 CDS NP_757213.1 26251173 1037310 complement(5109075..5110103) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4264; Escherichia coli O157:H7 ortholog: z4806; L-idonate regulatory protein 5110103 idnR 1037310 idnR Escherichia coli CFT073 L-idonate regulatory protein NP_757213.1 5109075 R 199310 CDS NP_757214.1 26251174 1037303 complement(5110140..5111459) 1 NC_004431.1 L-Ido transporter; Escherichia coli K-12 ortholog: b4265; Escherichia coli O157:H7 ortholog: z4770; Gnt-II system L-idonate transporter 5111459 idnT 1037303 idnT Escherichia coli CFT073 Gnt-II system L-idonate transporter NP_757214.1 5110140 R 199310 CDS NP_757215.1 26251175 1037302 complement(5111524..5112288) 1 NC_004431.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 5112288 idnO 1037302 idnO Escherichia coli CFT073 gluconate 5-dehydrogenase NP_757215.1 5111524 R 199310 CDS NP_757216.1 26251176 1037299 complement(5112312..5113343) 1 NC_004431.1 NAD-binding; L-idonate 5-dehydrogenase 5113343 idnD 1037299 idnD Escherichia coli CFT073 L-idonate 5-dehydrogenase NP_757216.1 5112312 R 199310 CDS NP_757217.1 26251177 1037293 5113560..5114123 1 NC_004431.1 Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805; D-gluconate kinase 5114123 idnK 1037293 idnK Escherichia coli CFT073 D-gluconate kinase NP_757217.1 5113560 D 199310 CDS NP_757218.1 26251178 1037290 complement(5114127..5115188) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4269; Escherichia coli O157:H7 ortholog: z5876; hypothetical protein 5115188 yjgB 1037290 yjgB Escherichia coli CFT073 hypothetical protein NP_757218.1 5114127 R 199310 CDS NP_757219.1 26251179 1037279 5115549..5116700 1 NC_004431.1 Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z5890; prophage P4 integrase 5116700 1037279 c5371 Escherichia coli CFT073 prophage P4 integrase NP_757219.1 5115549 D 199310 CDS NP_757220.1 26251180 1037278 complement(5116943..5120014) 1 NC_004431.1 Residues 1 to 1022 of 1023 are 51.23 pct identical to residues 1 to 1041 of 1043 from GenPept.129 : >gb|AAK02783.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein 5120014 1037278 c5372 Escherichia coli CFT073 hypothetical protein NP_757220.1 5116943 R 199310 CDS NP_757221.1 26251181 1037276 complement(5120028..5122040) 1 NC_004431.1 Residues 2 to 668 of 670 are 43.91 pct identical to residues 3 to 634 of 636 from GenPept.129 : >gb|AAK02782.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein 5122040 1037276 c5373 Escherichia coli CFT073 hypothetical protein NP_757221.1 5120028 R 199310 CDS NP_757222.1 26251182 1037275 5122071..5122415 1 NC_004431.1 hypothetical protein 5122415 1037275 c5374 Escherichia coli CFT073 hypothetical protein NP_757222.1 5122071 D 199310 CDS NP_757223.1 26251183 1037273 complement(5122185..5122343) 1 NC_004431.1 hypothetical protein 5122343 1037273 c5375 Escherichia coli CFT073 hypothetical protein NP_757223.1 5122185 R 199310 CDS NP_757224.1 26251184 1037272 complement(5122193..5122630) 1 NC_004431.1 hypothetical protein 5122630 1037272 c5376 Escherichia coli CFT073 hypothetical protein NP_757224.1 5122193 R 199310 CDS NP_757225.1 26251185 1037271 complement(5122627..5123328) 1 NC_004431.1 Residues 11 to 227 of 233 are 37.94 pct identical to residues 1 to 220 of 220 from GenPept.129 : >gb|AAK02781.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein 5123328 1037271 c5377 Escherichia coli CFT073 hypothetical protein NP_757225.1 5122627 R 199310 CDS NP_757226.1 26251186 1037270 complement(5123325..5126603) 1 NC_004431.1 Residues 1 to 1090 of 1092 are 60.92 pct identical to residues 1 to 1088 of 1089 from GenPept.129 : >gb|AAK02780.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein 5126603 1037270 c5378 Escherichia coli CFT073 hypothetical protein NP_757226.1 5123325 R 199310 CDS NP_757227.1 26251187 1037269 complement(5126603..5127508) 1 NC_004431.1 Residues 9 to 293 of 301 are 47.90 pct identical to residues 20 to 305 of 308 from GenPept.129 : >gb|AAM08019.1| (AY090559) hypothetical protein [Providencia rettgeri]; hypothetical protein 5127508 1037269 c5379 Escherichia coli CFT073 hypothetical protein NP_757227.1 5126603 R 199310 CDS NP_757228.1 26251188 1037268 5126849..5127133 1 NC_004431.1 hypothetical protein 5127133 1037268 c5380 Escherichia coli CFT073 hypothetical protein NP_757228.1 5126849 D 199310 CDS NP_757229.1 26251189 1037267 complement(5127677..5127964) 1 NC_004431.1 Residues 14 to 75 of 95 are 82.25 pct identical to residues 1 to 62 of 200 from GenPept.129 : >gb|AAL23316.1| (AE008911) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5127964 1037267 c5381 Escherichia coli CFT073 hypothetical protein NP_757229.1 5127677 R 199310 CDS NP_757230.1 26251190 1037264 5128222..5128935 1 NC_004431.1 Residues 87 to 229 of 237 are 81.81 pct identical to residues 1 to 143 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5128935 1037264 c5382 Escherichia coli CFT073 hypothetical protein NP_757230.1 5128222 D 199310 CDS NP_757231.1 26251191 1037262 complement(5128919..5129590) 1 NC_004431.1 Residues 46 to 199 of 223 are 30.57 pct identical to residues 20 to 172 of 188 from GenPept.129 : >dbj|BAB06239.1| (AP001515) transposase related protein (20) [Bacillus halodurans]; hypothetical protein 5129590 1037262 c5383 Escherichia coli CFT073 hypothetical protein NP_757231.1 5128919 R 199310 CDS NP_757232.1 26251192 1037260 complement(5129587..5129979) 1 NC_004431.1 hypothetical protein 5129979 1037260 c5384 Escherichia coli CFT073 hypothetical protein NP_757232.1 5129587 R 199310 CDS NP_757233.1 26251193 1037259 5130249..5130578 1 NC_004431.1 Residues 6 to 106 of 109 are 70.29 pct identical to residues 143 to 243 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5130578 1037259 c5385 Escherichia coli CFT073 hypothetical protein NP_757233.1 5130249 D 199310 CDS NP_757234.1 26251194 1037257 5131079..5131210 1 NC_004431.1 hypothetical protein 5131210 1037257 c5386 Escherichia coli CFT073 hypothetical protein NP_757234.1 5131079 D 199310 CDS NP_757235.1 26251195 1037256 complement(5131337..5132317) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4309; Escherichia coli O157:H7 ortholog: z5905; hypothetical protein 5132317 1037256 c5387 Escherichia coli CFT073 hypothetical protein NP_757235.1 5131337 R 199310 CDS NP_757236.1 26251196 1037254 complement(5132382..5133596) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4310; Escherichia coli O157:H7 ortholog: z5906; N-acetylneuraminic acid mutarotase 5133596 1037254 c5388 Escherichia coli CFT073 N-acetylneuraminic acid mutarotase NP_757236.1 5132382 R 199310 CDS NP_757237.1 26251197 1037252 complement(5133508..5134233) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4311; Escherichia coli O157:H7 ortholog: z5907; hypothetical protein 5134233 1037252 c5389 Escherichia coli CFT073 hypothetical protein NP_757237.1 5133508 R 199310 CDS NP_757238.1 26251198 1037251 complement(5135022..5135429) 1 NC_004431.1 hypothetical protein 5135429 1037251 c5390 Escherichia coli CFT073 hypothetical protein NP_757238.1 5135022 R 199310 CDS NP_757239.1 26251199 1037250 5135689..5136291 1 NC_004431.1 inversion of on/off regulator of fimA; tyrosine recombinase 5136291 fimB 1037250 fimB Escherichia coli CFT073 tyrosine recombinase NP_757239.1 5135689 D 199310 CDS NP_757240.1 26251200 1037249 5136769..5137365 1 NC_004431.1 inversion of on/off regulator of fimA; tyrosine recombinase 5137365 fimE 1037249 fimE Escherichia coli CFT073 tyrosine recombinase NP_757240.1 5136769 D 199310 CDS NP_757241.1 26251201 1037247 5137789..5138394 1 NC_004431.1 Type-1A pilin; Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z5912; Type-1 fimbrial protein, A chain 5138394 fimA 1037247 fimA Escherichia coli CFT073 Type-1 fimbrial protein, A chain NP_757241.1 5137789 D 199310 CDS NP_757242.1 26251202 1037245 5138459..5138998 1 NC_004431.1 Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913; fimbrin-like protein fimI 5138998 fimI 1037245 fimI Escherichia coli CFT073 fimbrin-like protein fimI NP_757242.1 5138459 D 199310 CDS NP_757243.1 26251203 1037243 5139035..5139760 1 NC_004431.1 Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z5914; chaperone protein fimC 5139760 fimC 1037243 fimC Escherichia coli CFT073 chaperone protein fimC NP_757243.1 5139035 D 199310 CDS NP_757244.1 26251204 1037242 5139826..5142462 1 NC_004431.1 Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z5915; outer membrane usher protein fimD 5142462 fimD 1037242 fimD Escherichia coli CFT073 outer membrane usher protein fimD NP_757244.1 5139826 D 199310 CDS NP_757245.1 26251205 1037237 5142469..5143002 1 NC_004431.1 Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916; FimF protein 5143002 fimF 1037237 fimF Escherichia coli CFT073 FimF protein NP_757245.1 5142469 D 199310 CDS NP_757246.1 26251206 1037236 complement(5142996..5143124) 1 NC_004431.1 hypothetical protein 5143124 1037236 c5398 Escherichia coli CFT073 hypothetical protein NP_757246.1 5142996 R 199310 CDS NP_757247.1 26251207 1037235 5143015..5143518 1 NC_004431.1 Escherichia coli K-12 ortholog: b4319; Escherichia coli O157:H7 ortholog: z5917; FimG protein 5143518 fimG 1037235 fimG Escherichia coli CFT073 FimG protein NP_757247.1 5143015 D 199310 CDS NP_757248.1 26251208 1037233 5143529..5144440 1 NC_004431.1 Escherichia coli K-12 ortholog: b4320; Escherichia coli O157:H7 ortholog: z5918; FimH protein 5144440 fimH 1037233 fimH Escherichia coli CFT073 FimH protein NP_757248.1 5143529 D 199310 CDS NP_757249.1 26251209 1037232 complement(5144682..5146025) 1 NC_004431.1 Gluconate permease 3; Escherichia coli K-12 ortholog: b4321; Escherichia coli O157:H7 ortholog: z5919; fructuronate transporter 5146025 gntP 1037232 gntP Escherichia coli CFT073 fructuronate transporter NP_757249.1 5144682 R 199310 CDS NP_757250.1 26251210 1037231 5146365..5147549 1 NC_004431.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5147549 uxuA 1037231 uxuA Escherichia coli CFT073 mannonate dehydratase NP_757250.1 5146365 D 199310 CDS NP_757251.1 26251211 1037227 5147630..5149090 1 NC_004431.1 Escherichia coli K-12 ortholog: b4323; Escherichia coli O157:H7 ortholog: z5921; D-mannonate oxidoreductase 5149090 uxuB 1037227 uxuB Escherichia coli CFT073 D-mannonate oxidoreductase NP_757251.1 5147630 D 199310 CDS NP_757252.1 26251212 1037226 5149305..5150078 1 NC_004431.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5150078 uxuR 1037226 uxuR Escherichia coli CFT073 DNA-binding transcriptional repressor UxuR NP_757252.1 5149305 D 199310 CDS NP_757253.1 26251213 1037225 5150483..5150875 1 NC_004431.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5150875 iraD 1037225 iraD Escherichia coli CFT073 DNA replication/recombination/repair protein NP_757253.1 5150483 D 199310 CDS NP_757254.1 26251214 1037223 complement(5150923..5151264) 1 NC_004431.1 Residues 1 to 113 of 113 are 95.57 pct identical to residues 424 to 536 of 536 from GenPept.129 : >gb|AAL61895.1| (AF289032) phosphoenolpyruvate-protein phosphoryltransferase PptE [Escherichia coli]; hypothetical protein 5151264 1037223 c5406 Escherichia coli CFT073 hypothetical protein NP_757254.1 5150923 R 199310 CDS NP_757255.1 26251215 1037222 complement(5151301..5152290) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4327; Escherichia coli O157:H7 ortholog: z5926; DNA-binding transcriptional regulator 5152290 yjiE 1037222 yjiE Escherichia coli CFT073 DNA-binding transcriptional regulator NP_757255.1 5151301 R 199310 CDS NP_757256.1 26251216 1037220 complement(5152277..5153449) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4328; Escherichia coli O157:H7 ortholog: z5927; isoaspartyl dipeptidase 5153449 iadA 1037220 iadA Escherichia coli CFT073 isoaspartyl dipeptidase NP_757256.1 5152277 R 199310 CDS NP_757257.1 26251217 1037212 complement(5153462..5153923) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4329; Escherichia coli O157:H7 ortholog: z5928; hypothetical protein 5153923 yjiG 1037212 yjiG Escherichia coli CFT073 hypothetical protein NP_757257.1 5153462 R 199310 CDS NP_757258.1 26251218 1037209 complement(5153920..5154615) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4330; Escherichia coli O157:H7 ortholog: z5929; hypothetical protein 5154615 yjiH 1037209 yjiH Escherichia coli CFT073 hypothetical protein NP_757258.1 5153920 R 199310 CDS NP_757259.1 26251219 1037208 5154615..5154746 1 NC_004431.1 hypothetical protein 5154746 1037208 c5411 Escherichia coli CFT073 hypothetical protein NP_757259.1 5154615 D 199310 CDS NP_757260.1 26251220 1037190 complement(5155419..5156597) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4332; Escherichia coli O157:H7 ortholog: z5933; hypothetical protein 5156597 yjiJ 1037190 yjiJ Escherichia coli CFT073 hypothetical protein NP_757260.1 5155419 R 199310 CDS NP_757261.1 26251221 1037188 complement(5156665..5157636) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4333; Escherichia coli O157:H7 ortholog: z5934; hypothetical protein 5157636 yjiK 1037188 yjiK Escherichia coli CFT073 hypothetical protein NP_757261.1 5156665 R 199310 CDS NP_757262.1 26251222 1037185 complement(5157590..5157847) 1 NC_004431.1 Residues 1 to 80 of 85 are 87.50 pct identical to residues 1 to 80 of 88 from GenPept.129 : >dbj|BAB38719.1| (AP002569) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 5157847 1037185 c5416 Escherichia coli CFT073 hypothetical protein NP_757262.1 5157590 R 199310 CDS NP_757263.1 26251223 1037182 complement(5157844..5158617) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4334; Escherichia coli O157:H7 ortholog: z5936; hypothetical protein 5158617 yjiL 1037182 yjiL Escherichia coli CFT073 hypothetical protein NP_757263.1 5157844 R 199310 CDS NP_757264.1 26251224 1037177 complement(5158621..5159793) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4335; Escherichia coli O157:H7 ortholog: z5937; hypothetical protein 5159793 yjiM 1037177 yjiM Escherichia coli CFT073 hypothetical protein NP_757264.1 5158621 R 199310 CDS NP_757265.1 26251225 1037169 complement(5159888..5161204) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4336; Escherichia coli O157:H7 ortholog: z5938; hypothetical protein 5161204 yjiN 1037169 yjiN Escherichia coli CFT073 hypothetical protein NP_757265.1 5159888 R 199310 CDS NP_757266.1 26251226 1037166 5161353..5162273 1 NC_004431.1 Escherichia coli K-12 ortholog: b2305; Escherichia coli O157:H7 ortholog: z5940; hypothetical protein 5162273 yfcI 1037166 yfcI Escherichia coli CFT073 hypothetical protein NP_757266.1 5161353 D 199310 CDS NP_757267.1 26251227 1037158 5162553..5164772 1 NC_004431.1 Residues 43 to 734 of 739 are 65.23 pct identical to residues 1 to 697 of 702 from GenPept.129 : >gb|AAM05803.1| (AE010933) conserved hypothetical protein [Methanosarcina acetivorans str. C2A]; hypothetical protein 5164772 1037158 c5421 Escherichia coli CFT073 hypothetical protein NP_757267.1 5162553 D 199310 CDS NP_757268.1 26251228 1037156 complement(5164819..5165160) 1 NC_004431.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 5165160 yjiW 1037156 yjiW Escherichia coli CFT073 endoribonuclease SymE NP_757268.1 5164819 R 199310 CDS NP_757269.1 26251229 1037148 complement(5165381..5167150) 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5946; restriction modification enzyme S subunit 5167150 1037148 c5423 Escherichia coli CFT073 restriction modification enzyme S subunit NP_757269.1 5165381 R 199310 CDS NP_757270.1 26251230 1037142 complement(5167150..5168673) 1 NC_004431.1 Methylase; Escherichia coli O157:H7 ortholog: z5947; restriction modification enzyme M subunit 5168673 1037142 c5424 Escherichia coli CFT073 restriction modification enzyme M subunit NP_757270.1 5167150 R 199310 CDS NP_757271.1 26251231 1037140 complement(5168686..5171118) 1 NC_004431.1 Endonuclease; Escherichia coli O157:H7 ortholog: z5948; restriction modification enzyme R subunit 5171118 1037140 c5425 Escherichia coli CFT073 restriction modification enzyme R subunit NP_757271.1 5168686 R 199310 CDS NP_757272.1 26251232 1037138 5171375..5173048 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5950; hypothetical protein 5173048 1037138 c5426 Escherichia coli CFT073 hypothetical protein NP_757272.1 5171375 D 199310 CDS NP_757273.1 26251233 1037135 complement(5173117..5174112) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4352; Escherichia coli O157:H7 ortholog: z5951; GTP-binding protein YjiA 5174112 yjiA 1037135 yjiA Escherichia coli CFT073 GTP-binding protein YjiA NP_757273.1 5173117 R 199310 CDS NP_757274.1 26251234 1037133 complement(5174084..5174287) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4353; Escherichia coli O157:H7 ortholog: z5952; hypothetical protein 5174287 1037133 c5428 Escherichia coli CFT073 hypothetical protein NP_757274.1 5174084 R 199310 CDS NP_757275.1 26251235 1037130 complement(5174405..5176570) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4354; Escherichia coli O157:H7 ortholog: z5953; hypothetical protein 5176570 yjiY 1037130 yjiY Escherichia coli CFT073 hypothetical protein NP_757275.1 5174405 R 199310 CDS NP_757276.1 26251236 1037129 5176932..5178596 1 NC_004431.1 MCP-I; Escherichia coli K-12 ortholog: b4355; Escherichia coli O157:H7 ortholog: z5955; methyl-accepting chemotaxis protein I 5178596 tsr 1037129 tsr Escherichia coli CFT073 methyl-accepting chemotaxis protein I NP_757276.1 5176932 D 199310 CDS NP_757277.1 26251237 1037125 complement(5178639..5179910) 1 NC_004431.1 Residues 1 to 422 of 423 are 42.31 pct identical to residues 1 to 423 of 428 from GenPept.129 : >gb|AAL95452.1| (AE010631) C4-dicarboxylate transporter large subunit [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 5179910 1037125 c5431 Escherichia coli CFT073 hypothetical protein NP_757277.1 5178639 R 199310 CDS NP_757278.1 26251238 1037122 complement(5179907..5180380) 1 NC_004431.1 Residues 19 to 144 of 157 are 29.92 pct identical to residues 7 to 133 of 174 from GenPept.129 : >emb|CAC26718.1| (AX066981) RXN02955 [Corynebacterium glutamicum]; hypothetical protein 5180380 1037122 c5432 Escherichia coli CFT073 hypothetical protein NP_757278.1 5179907 R 199310 CDS NP_757279.1 26251239 1037121 complement(5180444..5181253) 1 NC_004431.1 Residues 4 to 268 of 269 are 32.33 pct identical to residues 58 to 323 of 325 from GenPept.129 : >emb|CAC49506.1| (AL603646) C4-dicarboxylate transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti]; C4-dicarboxylate-binding periplasmic protein 5181253 1037121 c5433 Escherichia coli CFT073 C4-dicarboxylate-binding periplasmic protein NP_757279.1 5180444 R 199310 CDS NP_757280.1 26251240 1037120 complement(5181253..5181417) 1 NC_004431.1 hypothetical protein 5181417 1037120 c5434 Escherichia coli CFT073 hypothetical protein NP_757280.1 5181253 R 199310 CDS NP_757281.1 26251241 1037119 5182087..5183760 1 NC_004431.1 Escherichia coli K-12 ortholog: b4065; Escherichia coli O157:H7 ortholog: z5664; Na(+)/H(+) exchanger yjcE 5183760 1037119 c5435 Escherichia coli CFT073 Na(+)/H(+) exchanger yjcE NP_757281.1 5182087 D 199310 CDS NP_757282.1 26251242 1037118 complement(5183931..5184836) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4357; Escherichia coli O157:H7 ortholog: z5957; hypothetical protein 5184836 yjjM 1037118 yjjM Escherichia coli CFT073 hypothetical protein NP_757282.1 5183931 R 199310 CDS NP_757283.1 26251243 1037115 5184975..5185997 1 NC_004431.1 Escherichia coli K-12 ortholog: b4358; Escherichia coli O157:H7 ortholog: z5958; hypothetical protein 5185997 1037115 c5437 Escherichia coli CFT073 hypothetical protein NP_757283.1 5184975 D 199310 CDS NP_757284.1 26251244 1037114 complement(5186137..5188428) 1 NC_004431.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 5188428 mdoB 1037114 mdoB Escherichia coli CFT073 phosphoglycerol transferase I NP_757284.1 5186137 R 199310 CDS NP_757285.1 26251245 1037113 complement(5188682..5189179) 1 NC_004431.1 Protein P-18; Escherichia coli K-12 ortholog: b4360; Escherichia coli O157:H7 ortholog: z5960; hypothetical protein 5189179 yjjA 1037113 yjjA Escherichia coli CFT073 hypothetical protein NP_757285.1 5188682 R 199310 CDS NP_757286.1 26251246 1037112 complement(5189225..5189962) 1 NC_004431.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 5189962 dnaC 1037112 dnaC Escherichia coli CFT073 DNA replication protein DnaC NP_757286.1 5189225 R 199310 CDS NP_757287.1 26251247 1037111 complement(5189965..5190504) 1 NC_004431.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 5190504 dnaT 1037111 dnaT Escherichia coli CFT073 primosomal protein DnaI NP_757287.1 5189965 R 199310 CDS NP_757288.2 229106360 1037110 complement(5190612..5191085) 1 NC_004431.1 Protein P-14; Escherichia coli K-12 ortholog: b4363; Escherichia coli O157:H7 ortholog: z5963; hypothetical protein 5191085 yjjB 1037110 yjjB Escherichia coli CFT073 hypothetical protein NP_757288.2 5190612 R 199310 CDS NP_757289.1 26251249 1037107 complement(5191076..5191909) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4364; Escherichia coli O157:H7 ortholog: z5964; hypothetical protein 5191909 yjjP 1037107 yjjP Escherichia coli CFT073 hypothetical protein NP_757289.1 5191076 R 199310 CDS NP_757290.1 26251250 1037106 5192466..5193191 1 NC_004431.1 Escherichia coli K-12 ortholog: b4365; Escherichia coli O157:H7 ortholog: z5966; hypothetical protein 5193191 yjjQ 1037106 yjjQ Escherichia coli CFT073 hypothetical protein NP_757290.1 5192466 D 199310 CDS NP_757291.2 161486007 1037105 5193203..5193826 1 NC_004431.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5193826 bglJ 1037105 bglJ Escherichia coli CFT073 DNA-binding transcriptional activator BglJ NP_757291.2 5193203 D 199310 CDS NP_757292.1 26251252 1037103 complement(5193864..5194652) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4367; Escherichia coli O157:H7 ortholog: z5968; ferric iron reductase involved in ferric hydroximate transport 5194652 fhuF 1037103 fhuF Escherichia coli CFT073 ferric iron reductase involved in ferric hydroximate transport NP_757292.1 5193864 R 199310 CDS NP_757293.1 26251253 1037102 5194682..5195029 1 NC_004431.1 Residues 38 to 115 of 115 are 96.15 pct identical to residues 1 to 78 of 78 from SwissProt.40 : >sp|P55914|YJJZ_ECOLI Hypothetical protein yjjZ; hypothetical protein 5195029 1037102 c5447 Escherichia coli CFT073 hypothetical protein NP_757293.1 5194682 D 199310 CDS NP_757294.1 26251254 1037101 5194885..5195040 1 NC_004431.1 hypothetical protein 5195040 1037101 c5448 Escherichia coli CFT073 hypothetical protein NP_757294.1 5194885 D 199310 CDS NP_757295.1 26251255 1037093 complement(5195456..5195578) 1 NC_004431.1 hypothetical protein 5195578 1037093 c5449 Escherichia coli CFT073 hypothetical protein NP_757295.1 5195456 R 199310 CDS NP_757296.1 26251256 1037091 complement(5195590..5196621) 1 NC_004431.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 5196621 rsmC 1037091 rsmC Escherichia coli CFT073 16S ribosomal RNA m2G1207 methyltransferase NP_757296.1 5195590 R 199310 CDS YP_004853838.1 347357949 1037090 5196612..5197001 1 NC_004431.1 hypothetical protein 5197001 1037090 c5451 Escherichia coli CFT073 hypothetical protein YP_004853838.1 5196612 D 199310 CDS NP_757298.1 26251258 1037089 5196724..5197137 1 NC_004431.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5197137 holD 1037089 holD Escherichia coli CFT073 DNA polymerase III subunit psi NP_757298.1 5196724 D 199310 CDS NP_757299.1 26251259 1037088 5197106..5197552 1 NC_004431.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5197552 rimI 1037088 rimI Escherichia coli CFT073 ribosomal-protein-alanine N-acetyltransferase NP_757299.1 5197106 D 199310 CDS NP_757300.1 26251260 1037087 5197567..5198244 1 NC_004431.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5198244 yjjG 1037087 yjjG Escherichia coli CFT073 nucleotidase NP_757300.1 5197567 D 199310 CDS NP_757301.1 26251261 1037081 5198259..5198411 1 NC_004431.1 hypothetical protein 5198411 1037081 c5455 Escherichia coli CFT073 hypothetical protein NP_757301.1 5198259 D 199310 CDS NP_757302.1 26251262 1037078 5198335..5199924 1 NC_004431.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5199924 prfC 1037078 prfC Escherichia coli CFT073 peptide chain release factor 3 NP_757302.1 5198335 D 199310 CDS NP_757303.1 26251263 1037077 5200239..5200922 1 NC_004431.1 Escherichia coli K-12 ortholog: b4376; Escherichia coli O157:H7 ortholog: z5977; periplasmic protein 5200922 osmY 1037077 osmY Escherichia coli CFT073 periplasmic protein NP_757303.1 5200239 D 199310 CDS NP_757304.1 26251264 1037076 complement(5200284..5200976) 1 NC_004431.1 hypothetical protein 5200976 1037076 c5458 Escherichia coli CFT073 hypothetical protein NP_757304.1 5200284 R 199310 CDS NP_757305.1 26251265 1037071 5201019..5201210 1 NC_004431.1 Escherichia coli O157:H7 ortholog: z5978; hypothetical protein 5201210 1037071 c5459 Escherichia coli CFT073 hypothetical protein NP_757305.1 5201019 D 199310 CDS NP_757306.1 26251266 1037068 5201296..5202405 1 NC_004431.1 Escherichia coli K-12 ortholog: b4377; Escherichia coli O157:H7 ortholog: z5979; hypothetical protein 5202405 yjjU 1037068 yjjU Escherichia coli CFT073 hypothetical protein NP_757306.1 5201296 D 199310 CDS NP_757307.1 26251267 1037067 5202402..5203181 1 NC_004431.1 Escherichia coli K-12 ortholog: b4378; Escherichia coli O157:H7 ortholog: z5980; deoxyribonuclease YjjV 5203181 yjjV 1037067 yjjV Escherichia coli CFT073 deoxyribonuclease YjjV NP_757307.1 5202402 D 199310 CDS NP_757308.1 26251268 1037066 complement(5203398..5204261) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4379; Escherichia coli O157:H7 ortholog: z5981; hypothetical protein 5204261 yjjW 1037066 yjjW Escherichia coli CFT073 hypothetical protein NP_757308.1 5203398 R 199310 CDS NP_757309.1 26251269 1037065 complement(5204233..5205783) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4380; Escherichia coli O157:H7 ortholog: z5982; hypothetical protein 5205783 yjjI 1037065 yjjI Escherichia coli CFT073 hypothetical protein NP_757309.1 5204233 R 199310 CDS NP_757310.1 26251270 1037062 5205759..5205884 1 NC_004431.1 hypothetical protein 5205884 1037062 c5464 Escherichia coli CFT073 hypothetical protein NP_757310.1 5205759 D 199310 CDS NP_757311.1 26251271 1037031 5206017..5206820 1 NC_004431.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5206820 deoC 1037031 deoC Escherichia coli CFT073 deoxyribose-phosphate aldolase NP_757311.1 5206017 D 199310 CDS NP_757312.2 161486006 1037030 5206898..5208220 1 NC_004431.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5208220 deoA 1037030 deoA Escherichia coli CFT073 thymidine phosphorylase NP_757312.2 5206898 D 199310 CDS NP_757313.1 26251273 1037025 5208272..5209495 1 NC_004431.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5209495 deoB 1037025 deoB Escherichia coli CFT073 phosphopentomutase NP_757313.1 5208272 D 199310 CDS NP_757314.2 161486005 1037020 5209552..5210271 1 NC_004431.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5210271 deoD 1037020 deoD Escherichia coli CFT073 purine nucleoside phosphorylase NP_757314.2 5209552 D 199310 CDS NP_757315.1 26251275 1037006 5210429..5210938 1 NC_004431.1 Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 5210938 1037006 c5469 Escherichia coli CFT073 transposase NP_757315.1 5210429 D 199310 CDS NP_757316.1 26251276 1036990 5211150..5212481 1 NC_004431.1 Escherichia coli K-12 ortholog: b4385; hypothetical protein 5212481 yjjJ 1036990 yjjJ Escherichia coli CFT073 hypothetical protein NP_757316.1 5211150 D 199310 CDS NP_757317.1 26251277 1036989 complement(5212482..5213498) 1 NC_004431.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 5213498 lplA 1036989 lplA Escherichia coli CFT073 lipoate-protein ligase A NP_757317.1 5212482 R 199310 CDS NP_757318.1 26251278 1036987 complement(5213526..5214170) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4387; hypothetical protein 5214170 smp 1036987 smp Escherichia coli CFT073 hypothetical protein NP_757318.1 5213526 R 199310 CDS NP_757319.2 161486004 1036985 5214276..5215244 1 NC_004431.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5215244 serB 1036985 serB Escherichia coli CFT073 phosphoserine phosphatase NP_757319.2 5214276 D 199310 CDS NP_757320.1 26251280 1036984 5215245..5216675 1 NC_004431.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5216675 sms 1036984 sms Escherichia coli CFT073 DNA repair protein RadA NP_757320.1 5215245 D 199310 CDS NP_757321.2 161486003 1036976 5216696..5217928 1 NC_004431.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5217928 nadR 1036976 nadR Escherichia coli CFT073 nicotinamide-nucleotide adenylyltransferase NP_757321.2 5216696 D 199310 CDS NP_757322.1 26251282 1036965 5217942..5218352 1 NC_004431.1 Residues 32 to 135 of 136 are 36.19 pct identical to residues 4 to 108 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae]; hypothetical protein 5218352 1036965 c5476 Escherichia coli CFT073 hypothetical protein NP_757322.1 5217942 D 199310 CDS NP_757323.1 26251283 1036944 5218354..5218638 1 NC_004431.1 Residues 16 to 85 of 94 are 38.57 pct identical to residues 6 to 75 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) bacterial regulatory protein, merR family [Salmonella typhimurium LT2]; hypothetical protein 5218638 1036944 c5477 Escherichia coli CFT073 hypothetical protein NP_757323.1 5218354 D 199310 CDS NP_757324.1 26251284 1036942 complement(5218694..5220361) 1 NC_004431.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 5220361 yjjK 1036942 yjjK Escherichia coli CFT073 ABC transporter ATP-binding protein NP_757324.1 5218694 R 199310 CDS NP_757325.1 26251285 1036935 5220568..5222505 1 NC_004431.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5222505 slt 1036935 slt Escherichia coli CFT073 lytic murein transglycosylase NP_757325.1 5220568 D 199310 CDS NP_757326.1 26251286 1036896 5222595..5222921 1 NC_004431.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5222921 trpR 1036896 trpR Escherichia coli CFT073 Trp operon repressor NP_757326.1 5222595 D 199310 CDS NP_757327.2 161486002 1036892 complement(5222994..5223521) 1 NC_004431.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5223521 yjjX 1036892 yjjX Escherichia coli CFT073 NTPase NP_757327.2 5222994 R 199310 CDS NP_757328.1 26251288 1036888 5223573..5224220 1 NC_004431.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5224220 gpmB 1036888 gpmB Escherichia coli CFT073 phosphoglycerate mutase NP_757328.1 5223573 D 199310 CDS NP_757329.1 26251289 1036880 complement(5224217..5225086) 1 NC_004431.1 Escherichia coli K-12 ortholog: b4396; Escherichia coli O157:H7 ortholog: z5999; right origin-binding protein 5225086 rob 1036880 rob Escherichia coli CFT073 right origin-binding protein NP_757329.1 5224217 R 199310 CDS NP_757330.1 26251290 1036870 5225297..5225770 1 NC_004431.1 Escherichia coli K-12 ortholog: b4397; Escherichia coli O157:H7 ortholog: z6000; hypothetical protein 5225770 creA 1036870 creA Escherichia coli CFT073 hypothetical protein NP_757330.1 5225297 D 199310 CDS NP_757331.1 26251291 1036841 5225783..5226472 1 NC_004431.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5226472 creB 1036841 creB Escherichia coli CFT073 DNA-binding response regulator CreB NP_757331.1 5225783 D 199310 CDS NP_757332.1 26251292 1036835 5226472..5227896 1 NC_004431.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5227896 creC 1036835 creC Escherichia coli CFT073 sensory histidine kinase CreC NP_757332.1 5226472 D 199310 CDS NP_757333.1 26251293 1036814 5227954..5229306 1 NC_004431.1 Escherichia coli K-12 ortholog: b4400; Escherichia coli O157:H7 ortholog: z6003; hypothetical protein 5229306 creD 1036814 creD Escherichia coli CFT073 hypothetical protein NP_757333.1 5227954 D 199310 CDS NP_757334.1 26251294 1036809 complement(5229366..5230082) 1 NC_004431.1 Dye resistance protein; Escherichia coli K-12 ortholog: b4401; Escherichia coli O157:H7 ortholog: z6004; two-component response regulator 5230082 arcA 1036809 arcA Escherichia coli CFT073 two-component response regulator NP_757334.1 5229366 R 199310 CDS NP_757335.1 26251295 1036801 5230178..5230318 1 NC_004431.1 Escherichia coli K-12 ortholog: b4402; Escherichia coli O157:H7 ortholog: z6005; hypothetical protein 5230318 yjjY 1036801 yjjY Escherichia coli CFT073 hypothetical protein NP_757335.1 5230178 D 199310 CDS NP_757336.2 229106359 1036781 5230718..5231404 1 NC_004431.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5231404 lasT 1036781 lasT Escherichia coli CFT073 RNA methyltransferase NP_757336.2 5230718 D 199310 CDS