-- dump date 20140619_085910 -- class Genbank::CDS -- table cds_note -- id note NP_052608.1 type II secretion pathway related protein NP_052609.1 type II secretion pathway related protein NP_052610.1 type II secretion pathway related protein NP_052611.1 type II secretion pathway related protein NP_052612.1 type II secretion pathway related protein NP_052613.1 type II secretion pathway related protein NP_052614.1 type II secretion pathway related protein NP_052615.1 type II secretion pathway related protein NP_052616.1 type II secretion pathway related protein NP_052617.1 type II secretion pathway related protein NP_052618.1 type II secretion pathway related protein NP_052619.1 type II secretion pathway related protein NP_052620.1 type II secretion pathway related protein NP_052621.1 hypothetical 12.7 kDa protein encoded in insertion element IS911; similar to SwissProt accession number P39213 NP_052622.1 similar to PIR accession number S56510 NP_052627.1 similar to SwissProt accession number P42193 NP_052628.1 probable site-specific recombinase in AFA region; similar to SwissProt accession number Q47036 NP_052630.2 replication protein RepFIB (P307 replicon); similar to PIR accession number A32310 NP_052634.1 CcdA protein; protein H; LynA; similar to SwissProt accession number P05702 NP_052635.1 cytotoxic protein; controlled cell death protein; post-segregation toxin; toxin addiction system NP_052636.1 Protein D; similar to SwissProt accession number P06615 NP_052637.1 similar to SwissProt accession number P16942; transposase encoded in insertion sequence IS629 NP_052638.1 hypothetical 12 kDa protein encoded in insertion sequence IS629; similar to SwissProt accession number P16941 NP_052640.1 Protein A; similar to SwissProt accession number P08866 NP_052641.1 SopB NP_052642.1 similar to SwissProt accession number P19593 NP_052645.1 similar to PIR accession number S18997 NP_052649.1 antirestriction protein; similar to SwissProt accession number P52603 NP_052656.1 similar to SwissProt accession number P18310; helix-destabilizing protein NP_052658.1 responsible for plasmid SOS inhibition; similar to PIR accession number S01898 NP_052659.1 PsiA NP_052660.1 F leading maintenance protein; similar to SwissProt accession number P16077 NP_052661.1 similar to PIR accession number B38529 NP_052663.1 encoded in insertion sequence IS3 NP_052664.1 encoded in insertion sequence element IS21; similar to SwissProt accession number P15025 NP_052665.1 similar to SwissProt accession number P18177 NP_052666.1 encoded in insertion sequence IS3 NP_052667.1 similar to SwissProt accession number P16941 NP_052669.1 similar to SwissProt accession number P22710 NP_052670.1 similar to SwissProt accession number Q99390 NP_052671.1 conjugal transfer repressor; similar to SwissProt accession number P08315 NP_052672.1 similar to SwissProt accession number Q99342 NP_052673.1 similar to PIR accession number S28661 NP_052674.1 similar to SwissProt accession number P03847 NP_052675.1 RepA NP_052678.1 stability (stb) locus of IncFII plasmid NR1; similar to SwissProt accession number P11907 NP_052681.1 encoded in insertion sequence IS91; similar to PIR accession number S23782 NP_052684.1 encoded in insertion sequence IS629; similar to SwissProt accession number P16942 NP_052685.1 extracellular serine protease NP_052688.1 similar to SwissProt accession number P32678 NP_052689.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA NP_308028.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon NP_308029.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways NP_308030.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate NP_308031.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine NP_308032.1 similar to B0005_ECOLI gi|1786186 (conserved in Escherichia coli K-12) NP_308033.1 similar to YAAA_ECOLI gi|1786187 (conserved in Escherichia coli K-12) NP_308034.1 similar to YAAJ_ECOLI gi|1786188 (conserved in Escherichia coli K-12) NP_308035.1 Maintains the balance of metabolites in the pentose-phosphate pathway NP_308036.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis NP_308037.1 similar to YAAH_ECOLI gi|1786191 (conserved in Escherichia coli K-12) NP_308038.1 similar to B0011_ECOLI gi|1786193 (conserved in Escherichia coli K-12) NP_308040.1 similar to YAAI_ECOLI gi|1786195 (conserved in Escherichia coli K-12) NP_308041.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_308042.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_308043.1 similar to GEF_ECOLI gi|1786200 (conserved in Escherichia coli K-12) NP_308044.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH NP_308045.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC NP_308049.1 similar to outer membrane usher protein precursors e.g. YehB [Escherichia coli K-12] gi|465572|sp|P33341|YEHB_ECOLI NP_308050.1 similar to fimbrial chaperones e.g. YehC [Escherichia coli] gi|465573|sp|P33342|YEHC_ECOLI NP_308051.1 similar to YehD [Escherichia coli] gi|465574|sp|P33343|YEHD_ECOLI, long polar fimbrial major protein [Salmonella typhimurium] gi|1170815|sp|P43660|LPFA_SALT NP_308053.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_308054.1 similar to B0024_ECOLI gi|1786207 (conserved in Escherichia coli K-12) NP_308055.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_308056.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme NP_308057.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_308058.1 similar to SLPA_ECOLI gi|1786211 (conserved in Escherichia coli K-12) NP_308059.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_308060.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides NP_308061.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_308062.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers NP_308063.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity NP_308064.2 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons NP_308065.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities NP_308066.2 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA NP_308067.1 similar to CAIC_ECOLI gi|1786221 (conserved in Escherichia coli K-12) NP_308068.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine NP_308069.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA NP_308070.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism NP_308071.2 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase NP_308072.1 involved in electron transfer during carnitine metabolism NP_308073.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction NP_308074.1 similar to FIXX_ECOLI gi|1786228 (conserved in Escherichia coli K-12) NP_308075.1 similar to YAAU_ECOLI gi|1786229 (conserved in Escherichia coli K-12) NP_308076.1 Required for full activity of KefC, a potassium-proton antiporter NP_308077.1 transport system that facilitates potassium-efflux NP_308078.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate NP_308079.1 similar to CcdA protein (LetA protein) of F plasmid [Escherichia coli] gi|9507755|ref|NP_061421.1 NP_308080.1 similar to CcdB protein (LetB protein) of plasmid F [Escherichia coli] gi|9507756|ref|NP_061422.1 NP_308081.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP NP_308082.1 protein associated with Co2+ and Mg2+ efflux NP_308083.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_308084.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) NP_308085.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB NP_308086.1 determines N-hexane tolerance and is involved in outer membrane permeability NP_308087.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system NP_308088.1 similar to YABP_ECOLI gi|1786242 (conserved in Escherichia coli K-12) NP_308089.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs NP_308090.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA NP_308091.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C NP_308092.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source NP_308093.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism NP_308094.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate NP_308095.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose NP_308096.1 similar to YABI_ECOLI gi|1786252 (conserved in Escherichia coli K-12) NP_308097.1 with TbpA and ThiP is part of the thiamine and TPP transport system NP_308098.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine NP_308099.1 part of the thiamine and TPP transport system tbpA-thiPQ NP_308100.1 similar to YABP_ECOLI gi|2506583|sp|P39220 NP_308101.1 activates sgrS under glucose-phosphate stress conditions NP_308102.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D NP_308103.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate NP_308104.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis NP_308105.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis NP_308106.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis NP_308107.2 activator for leuABCD operon; member of LysR family of transcriptional activators NP_308108.2 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive NP_308109.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit NP_308111.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism NP_308112.1 MraZ; UPF0040; crystal structure shows similarity to AbrB NP_308113.1 similar to YABC_ECOLI gi|1786270 (conserved in Escherichia coli K-12) NP_308114.1 membrane bound cell division protein at septum containing leucine zipper motif NP_308115.1 septum formation protein; similar to FTSI_ECOLI gi|1786272 (conserved in Escherichia coli K-12) NP_308116.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_308117.1 similar to MURF_ECOLI gi|1786274 (conserved in Escherichia coli K-12) NP_308118.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_308119.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_308120.1 integral membrane protein involved in stabilizing FstZ ring during cell division NP_308121.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_308122.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis NP_308123.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_308124.1 involved in septum formation NP_308125.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane NP_308126.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function NP_308127.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis NP_308128.2 secM translational pause allows for the initiation of secA translation NP_308129.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins NP_308130.1 similar to MUTT_ECOLI gi|1786288 (conserved in Escherichia coli K-12) NP_308132.1 similar to YACG_ECOLI gi|1786290 (conserved in Escherichia coli K-12) NP_308133.1 similar to YACF_ECOLI gi|1786291 (conserved in Escherichia coli K-12) NP_308134.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_308135.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate NP_308137.1 integral membrane protein; similar to HOFC_ECOLI gi|1786295 (conserved in Escherichia coli K-12) NP_308138.1 integral membrane protein; similar to HOFB_ECOLI gi|1786296 (conserved in Escherichia coli K-12) NP_308139.1 similar to PPDD_ECOLI gi|1786297 (conserved in Escherichia coli K-12) NP_308140.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide NP_308141.1 similar to AMPD_ECOLI gi|1786300 (conserved in Escherichia coli K-12) NP_308142.1 involved in regulation of beta-lactamase; signaling protein NP_308143.1 similar to AROP_ECOLI gi|1786302 (conserved in Escherichia coli K-12) NP_308144.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex NP_308145.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC NP_308146.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains NP_308147.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_308148.1 similar to YACH_ECOLI gi|1786308 (conserved in Escherichia coli K-12) NP_308149.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate NP_308150.2 similar to YACL_ECOLI gi|1786310 (conserved in Escherichia coli K-12) NP_308151.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine NP_308152.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine NP_308153.2 similar to YACC_ECOLI gi|1786313 (conserved in Escherichia coli K-12) NP_308154.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification NP_308155.1 similar to GCD_ECOLI gi|1786316 (conserved in Escherichia coli K-12) NP_308156.2 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively NP_308157.1 catalyzes the interconversion of bicarbonate and carbon dioxide NP_308158.1 similar to YADG_ECOLI gi|1786319 (conserved in Escherichia coli K-12) NP_308159.1 similar to YADH_ECOLI gi|1786320 (conserved in Escherichia coli K-12) NP_308160.1 similar to YADI_ECOLI gi|1786321 (conserved in Escherichia coli K-12) NP_308161.1 similar to YADE_ECOLI gi|1786322 (conserved in Escherichia coli K-12) NP_308162.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) NP_308163.1 similar to YADD_ECOLI gi|1786324 (conserved in Escherichia coli K-12) NP_308164.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine NP_308165.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate NP_308166.1 probable fimbrial protein, similar to probable fimbrial proteins e.g. [Escherichia coli] gi|538781|pir||B47152, long polar fimbrial minor protein LpfE [Salmonella typhimurium] gi|1170819|sp|P43664|LPFE_SALTY NP_308167.1 probable fimbrial protein, similar to fimbrial protein YadK [Escherichia coli] gi|549488|sp|P37016|YADK_ECOLI NP_308168.1 probable fimbrial protein, similar to fimbrial protein YadL [Escherichia coli] gi|549489|sp|P37017|YADL_ECOLI NP_308169.1 probable fimbrial protein, similar to fimbrial-like protein YadM [Escherichia coli] gi|549490|sp|P37018|YADM_ECOLI NP_308170.1 similar to the fimbrial usher protein PapC NP_308171.1 similar to ECPD_ECOLI gi|1786333 NP_308172.1 similar to YADN_ECOLI gi|1786334 NP_308173.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP NP_308174.2 Polymerase that creates the 3' poly(A) tail found in some mRNA's NP_308175.2 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu NP_308176.1 similar to DKSA_ECOLI gi|1786338 (conserved in Escherichia coli K-12) NP_308177.1 Regulatory factor involved in maltose metabolism NP_308178.2 similar to YADP_ECOLI gi|1786341 (conserved in Escherichia coli K-12) NP_308179.1 similar in sequence to the ATP-dependent RNA helicase HrpA NP_308180.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell NP_308181.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein NP_308182.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter NP_308183.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores NP_308184.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome NP_308185.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway NP_308186.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation NP_308187.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors NP_308188.1 similar to YADS_ECOLI gi|1786352 (conserved in Escherichia coli K-12) NP_308189.1 solute binding component of the vitamin B12 transport system BtuCDF NP_308190.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine NP_308191.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate NP_308192.1 protease Do; required at high temperature; degrades damaged proteins NP_308193.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization NP_308194.1 similar to YAEH_ECOLI gi|1786359 (conserved in Escherichia coli K-12) NP_308195.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway NP_308196.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein NP_308197.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn NP_308198.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_308199.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_308200.1 Catalyzes the phosphorylation of UMP to UDP NP_308201.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_308202.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_308203.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_308204.2 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate NP_308205.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response NP_308206.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins NP_308207.1 histone-like protein; similar to HLPA_ECOLI gi|1786375 (conserved in Escherichia coli K-12) NP_308208.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis NP_308209.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_308210.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis NP_308211.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM NP_308212.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_308213.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_308214.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_308215.1 similar to LDCC_ECOLI gi|1786384 (conserved in Escherichia coli K-12) NP_308216.2 similar to YAER_ECOLI gi|1786385 (conserved in Escherichia coli K-12) NP_308217.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase NP_308218.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination NP_308219.1 similar to YAEQ_ECOLI gi|1786388 (conserved in Escherichia coli K-12) NP_308220.1 similar to YAEJ_ECOLI gi|1786389 (conserved in Escherichia coli K-12) NP_308221.1 similar to CUTF_ECOLI gi|1786390 (conserved in Escherichia coli K-12) NP_308222.1 similar to YAEF_ECOLI gi|1786391 (conserved in Escherichia coli K-12) NP_308223.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_308224.1 similar to YAEB_ECOLI gi|1786393 (conserved in Escherichia coli K-12) NP_308225.1 similar to RCSF_ECOLI gi|1786394 (conserved in Escherichia coli K-12) NP_308226.1 similar to YAEC_ECOLI gi|1786396 (conserved in Escherichia coli K-12) NP_308227.1 part of the MetNIQ methionine uptake system NP_308228.1 part of the metNIQ transport system for methionine NP_308229.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate NP_308230.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid NP_308231.1 similar to YAFC_ECOLI gi|1786401 (conserved in Escherichia coli K-12) NP_308232.1 similar to YAFD_ECOLI gi|1786403 (conserved in Escherichia coli K-12) NP_308233.1 C-terminal part (52-256 in 256 aa) is similar to YEFE_ECOLI gi|1786404 (conserved in Escherichia coli K-12) NP_308234.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall NP_308235.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione NP_308236.1 similar to YAFS_ECOLI gi|1786407 (conserved in Escherichia coli K-12) NP_308237.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_308238.1 3'-5' exonuclease of DNA polymerase III NP_308243.1 similar tohemolysin-coregulated protein Hcp [Vibrio cholerae] gi|7467495|pir||T10891, hypothetical 44.2 kD protein YhhZ [Escherichia coli (strain K-12)] gi|1176284|sp|P46855|YHHZ_ECOLI NP_308245.1 similar to IcmF protein [Legionella pneumophila] gi|7465644|pir||T18341 NP_308250.1 similar to ATP-dependent Clp proteinase ATP-binding chains ClpB e.g. gi|7428220|pir||T07807 NP_308252.1 similar to hypothetical protein z29f Vibrio cholerae CAA13133 NP_308257.1 similar to base plate protein and acidic lysozyme [coliphage T4] gi|137980|sp|P09425|VG25_BPT4 NP_308258.1 similar to hypothetical 54.5 kDa protein [Edwardsiella ictaluri] gi|2708666|gb|AAB92576.1 NP_308260.1 similar to hypothetical protein [Escherichia coli] gi|2920642|gb|AAC32477.1; similar tohypothetical 19.5 kDa protein [Edwardsiella ictaluri] gi|2708667|gb|AAB92577.1 NP_308263.1 similar to VgrG [Escherichia coli strain ec11] gi|2920640|gb|AAC32475.1 NP_308264.1 Rhs protein; similar to RhsH proteins e.g. [Escherichia coli strain EC45] gi|2920634|gb|AAC32471.1 NP_308265.1 similar to YbeQ [Escherichia coli] gi|3025010|sp|P77234; similar toYibG [Escherichia coli] gi|418454|sp|P32106|YIBG_ECOLI NP_308268.1 similar to H repeat-associated proteins e.g. [Escherichia coli RhsB element] gi|140772|sp|P28912 NP_308269.1 Rhs protein; similar to Rhs core proteins e.g. RhsE [Escherichia coli] gi|2507113|sp|P24211|RHSE_ECOLI NP_308270.1 similar to N-terminal parts of hypothetical proteins e.g. ORF E2 in Rhs element [Escherichia coli] gi|2851489|sp|P31991 NP_308271.1 similar to C-terminal parts of hypothetical proteins e.g. ORF E2 in Rhs element [Escherichia coli] gi|2851489|sp|P31991 NP_308272.1 similar to H repeat-associated proteins e.g. [Escherichia coli RhsB element] gi|7465875|pir||E64898 NP_308273.1 similar to YAFV_ECOLI gi|1786412 (conserved in Escherichia coli K-12) NP_308274.1 inactivates vertebrate C-type lysozyme NP_308275.2 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA NP_308276.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate NP_308277.1 similar to YAFJ_ECOLI gi|1786417 (conserved in Escherichia coli K-12) NP_308278.1 similar to YAFK_ECOLI gi|1786418 (conserved in Escherichia coli K-12) NP_308279.1 similar to YAFQ_ECOLI gi|1786419 (conserved in Escherichia coli K-12) NP_308280.1 damage-inducible protein; similar to DINJ_ECOLI gi|1786420 (conserved in Escherichia coli K-12) NP_308281.1 similar to YAFL_ECOLI gi|1786421 (conserved in Escherichia coli K-12) NP_308282.1 similar to N-terminal part (1-98 in 165 aa) of YAFM_ECOLI gi|1786422 NP_308283.1 similar to FHIA_ECOLI gi|1786423 (conserved in Escherichia coli K-12) NP_308284.1 similar to MBHA_ECOLI gi|1786424 (conserved in Escherichia coli K-12) NP_308285.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function NP_308286.1 similar to YAFN_ECOLI gi|1786426 (conserved in Escherichia coli K-12) NP_308287.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function NP_308288.1 similar to YAFP_ECOLI gi|1786428 (conserved in Escherichia coli K-12) NP_308289.1 similar to B0235_ECOLI gi|1786430 (conserved in Escherichia coli K-12) NP_308290.1 similar to release factor 1 and 2 NP_308291.1 similar to PEPD_ECOLI gi|1786432 (conserved in Escherichia coli K-12) NP_308292.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively NP_308293.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation NP_308294.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS NP_308295.1 outer membrane pore protein; similar to PHOE_ECOLI gi|1786436 (conserved in Escherichia coli K-12) NP_308296.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis NP_308297.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway NP_308298.1 similar to integrases e.g. [Shigella flexneri bacteriophage V] gi|2465477|gb|AAB72135.1 NP_308299.1 similar to transcription antitermination protein N [Bacteriophage lambda] gi|73111|pir||VNBPL NP_308300.1 similar to N-terminal part of hypothetical proteins HP1334 [Helicobacter pylori (strain 26695)] gi|7464516|pir||F64686, hypothetical protein [Neisseria meningitidis] gi|6900422|e NP_308301.1 similar to prophage repressor CI e.g. [Bacteriophage HK97] gi|6901592|gb|AAF31095.1|AF069529_8 (AF069529) NP_308302.1 similar to regulatory protein Cro [phage lambda] gi|73101|pir||RCBPL, similar toCro proteins e.g. [Bacteriophage HK97] gi|6901626|gb|AAF31129.1 NP_308303.1 regulatory protein; similar to regulatory protein cII [Bacteriophage lambda] gi|73106|pir||QCBP2L NP_308307.1 similar to tail fiber proteins e.g. [Bacteriophage HK97] gi|6901608|gb|AAF31111.1| (AF069529); Sc/SvQ proteins (DNA inversion product) [Escherichia coli plasmid p15B] NP_308308.1 similar to hypothetical proteins e.g. YcfA protein [Escherichia coli] gi|2506641|sp|P09153|YCFA_ECOLI; Gp29 [Bacteriophage HK97] gi|6901609|gb|AAF31112.1; T protein [Escherichia col NP_308309.1 similar to hypothetical proteins e.g. YfdK [Escherichia coli(strain K-12)] gi|3915468|sp|P77656|YFDK_ECOLI NP_308310.1 similar to hypothetical proteins e.g. YfdL [Escherichia coli (strain K-12)] gi|2495635|sp|P76508|YFDL_ECOLI; tail fiber protein YcfE [Escherichia coli cryptic prophage e14] gi|7444558|p NP_308311.1 similar to DNA-invertases e.g. Pin [Escherichia coli] gi|72978|pir||JWEC NP_308312.1 similar to hypothetical protein [Deinococcus radiodurans (strain R1)] gi|7472205|pir||B75431 NP_308314.1 similar to transcription regulators e.g. AraC family transcriptional regulator YdeO gi|6176587|sp|P76135|YDEO_ECOLI NP_308315.1 similar to C-terminal parts of hypothetical proteins e.g. [Escherichia coli insertion sequence IS2] gi|140808|sp|P19777|YI22_ECOLI; may be disrupted NP_308316.1 similar to integrases e.g. [phage phi-R73] gi|93827|pir||A42465 NP_308321.1 similar to hypothetical protein PFB0765w [malaria parasite] gi|7494317|pir||E71606 NP_308323.1 probable transcription activator; similar to Ogr family e.g. LsrS [Rahnella aquatilis] gi|93826|pir||E42465; delta protein [phage phi-R73] gi|93826|pir||E42465 NP_308324.1 probable polarity suppression protein (amber mutation-suppression protein); similar to Psu like proteins e.g. Psu [Bacteriophage P4] gi|1351414|sp|P05460|VPSU_BPP4 NP_308325.1 head size determination, similar to head size determination proteins e.g. Sid [phage phi-R73] gi|93821|pir||F42465 NP_308326.1 probable DNA binding protein, similar to hypothetical proteins e.g. DNA binding protein ORF88 [satellite phage P4] gi|140147|sp|P12552|Y9K_BPP4 NP_308327.1 similar to CI repressors e.g. [Bacteriophage P4] gi|1262833|emb|CAA35902.1 NP_308329.1 copy number control protein; similar to orf106 [satellite phage P4] gi|75896|pir||QQBPP4 NP_308330.1 similar to DNA primases e.g. alpha gene product [satellite phage P4] gi|130905|sp|P10277|PRIM_BPP4 NP_308331.1 similar to hypothetical protein sll1401 [Synechocystis sp. (strain PCC 6803)] gi|7470073|pir||S74462 NP_308332.1 similar to YAGP_ECOLI gi|1786476 NP_308333.1 similar to oxidoreductases e.g. [Streptomyces coelicolor A3(2)] gi|6137024|emb|CAB59579.1 NP_308336.1 similar to transcriptional regulators e.g. [Xylella fastidiosa] gi|9106842|gb|AAF84577.1|AE003999_5 NP_308337.1 similar to hypothetical protein [Pseudomonas aeruginosa] gi|732227|sp|Q01609|YODE_PSEAE NP_308338.1 similar to transporters e.g. OpdE [Pseudomonas aeruginosa] gi|400678|sp|Q01602|OPDE_PSEAE NP_308340.1 similar to YAGQ_ECOLI gi|1786477 (conserved in Escherichia coli K-12) NP_308341.1 similar to YAGR_ECOLI gi|1786478 (conserved in Escherichia coli K-12) NP_308342.1 similar to YAGS_ECOLI gi|1786479 (conserved in Escherichia coli K-12) NP_308343.1 similar to YAGT_ECOLI gi|1786480 (conserved in Escherichia coli K-12) NP_308344.1 similar to YAGU_ECOLI gi|1786481 (conserved in Escherichia coli K-12) NP_308345.1 similar to YKGJ_ECOLI gi|2367105 (conserved in Escherichia coli K-12) NP_308346.1 similar to YAGV_ECOLI gi|1786482 (conserved in Escherichia coli K-12) NP_308347.1 similar to YAGW_ECOLI gi|1786483 (conserved in Escherichia coli K-12) NP_308348.1 similar to YAGX_ECOLI gi|1786484 (conserved in Escherichia coli K-12) NP_308349.1 similar to YAGY_ECOLI gi|1786485 (conserved in Escherichia coli K-12) NP_308350.1 similar to YAGZ_ECOLI gi|1786486 (conserved in Escherichia coli K-12) NP_308351.1 similar to YKGK_ECOLI gi|2367106 (conserved in Escherichia coli K-12) NP_308353.1 similar to YKGL_ECOLI gi|2367107 (conserved in Escherichia coli K-12) NP_944503.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif NP_308354.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_308355.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli O157:H7 strain EDL933}] gi|3414881|gb|AAC31492.1 NP_308356.1 similar to hypothetical proteins e.g. L0014 [Escherichia coli O157:H7 strain EDL933}] gi|3288157|emb|CAA11510.1 NP_308357.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 strain EDL933}] gi|3414883|gb|AAC31494.1 NP_308358.1 similar to YqiG [Bacillus subtilis] gi|1731054|sp|P54524|YQIG_BACSU NP_308359.1 similar to hypothetical protein [Escherichia coli K-12] gi|3183244|sp|P76049|YCJY_ECOLI NP_308360.1 similar to transcriptional regulators e.g. [Escherichia coli] gi|2495398|sp|P75836|YCAN_ECOLI NP_308362.1 similar to oxidoreductase, [Thermotoga maritima] gi|7431104|pir||A72308 NP_308363.1 similar to probable membrane protein b1978 [Escherichia coli] gi|7466779|pir||D64962; similar toinvasins e.g. [Yersinia pestis] gi|726319|gb|AAA96352.1 NP_308364.1 similar to probable transcription regulator YkgA [Escherichia coli] gi|2495375|sp|P77601|YKGA_ECOLI NP_308365.2 similar to reductases e.g. oxidoreductase [Thermotoga maritima] gi|7431104|pir||A72308 NP_308366.1 similar to YKGB_ECOLI gi|1786492 (conserved in Escherichia coli K-12) NP_308368.1 similar to YKGI_ECOLI gi|1786494 (conserved in Escherichia coli K-12) NP_308369.2 Involved in disulfide oxidoreductase activity and electron transport NP_308370.1 similar to YKGD_ECOLI gi|1786496 (conserved in Escherichia coli K-12) NP_308371.1 similar to YKGE_ECOLI gi|1786497 (conserved in Escherichia coli K-12) NP_308372.1 similar to YKGF_ECOLI gi|1786498 (conserved in Escherichia coli K-12) NP_308373.2 similar to YKGG_ECOLI gi|1786499 (conserved in Escherichia coli K-12) NP_308374.1 similar to B0309_ECOLI gi|1786500 (conserved in Escherichia coli K-12) NP_308375.1 similar to YKGH_ECOLI gi|1786502 NP_308376.1 similar to hypothetical protein YaiU [Escherichia coli] gi|2495526|sp|P75700|YAIU_ECOLI NP_308377.1 similar to high molecular weight adhesin e.g. HmwA [Haemophilus influenzae] gi|5929966|gb|AAD56660.1|AF180944_1 NP_308379.1 similar to hypothetical protein [Escherichia coli] gi|2506596|sp|P21514|YAHA_ECOLI; similar to regulators e.g. BvgA [Bordetella bronchiseptic] gi|115157|sp|P16574|BVGA_BORPE NP_308384.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine NP_308385.1 catalyzes the formation of betaine from betaine aldehyde NP_308386.2 HTH-type; bet1; Repressor involved in choline regulation of the bet genes NP_308387.1 proton-motive-force-driven choline transporter NP_308389.1 similar to IgA1 protease homolog MisL [Salmonella typhimurium pathogenicity island SPI-3] gi|4324610|gb|AAD16954.1|; similar to VirG [Shigella flexneri] gi|96922|pir||A32247; probable adhesin; AidA-I adhesin precursor e.g. [Escherichia coli plasmid F] gi|8918851|dbj|BAA97898.1 NP_308390.1 similar to YAHA_ECOLI gi|1786507 (conserved in Escherichia coli K-12) NP_308393.1 similar to YAHC_ECOLI gi|1786509 (conserved in Escherichia coli K-12) NP_308394.1 similar to YAHD_ECOLI gi|1786511 (conserved in Escherichia coli K-12) NP_308395.1 similar to YAHE_ECOLI gi|1786512 (conserved in Escherichia coli K-12) NP_308396.1 similar to YAHF_ECOLI gi|1786513 (conserved in Escherichia coli K-12) NP_308397.1 similar to YAHG_ECOLI gi|1786514 (conserved in Escherichia coli K-12) NP_308398.1 similar to YAHH_ECOLI gi|1786515 (conserved in Escherichia coli K-12) NP_308399.1 forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate NP_308400.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain NP_308401.1 similar to sugar-binding proteins e.g. b1516 [Escherichia coli] gi|7466925|pir||G64905 NP_308402.1 similar to N-terminal part of ABC transporter ATP-binding proteins e.g. [Streptomyces coelicolor A3(2)] gi|7479110|pir||T34924 NP_308403.1 similar to C-terminal part of sugar ABC transporter ATP-binding proteins e.g. [Bacillus subtilis] gi|7404442|sp|P36947|RBSA_BACSU NP_308404.1 similar to ABC transporter permeases e.g. RbsC[Bacillus subtilis] gi|7446897|pir||B69690; [Escherichia coli] gi|400960|sp|P04984|RBSC_ECOLI NP_308405.1 similar to ABC transporter permeases e.g. RbsC [Escherichia coli] gi|78833|pir||C26304; [Bacillus subtilis] gi|7446897|pir||B69690 NP_308406.1 similar to YAHK_ECOLI gi|1786518 (conserved in Escherichia coli K-12) NP_308407.1 similar to YAHL_ECOLI gi|1786519 (conserved in Escherichia coli K-12) NP_308409.2 similar to YAHN_ECOLI gi|1786522 (conserved in Escherichia coli K-12) NP_308410.1 similar to YAHO_ECOLI gi|1786523 (conserved in Escherichia coli K-12) NP_308411.1 similar to PRPR_ECOLI gi|1786524 (conserved in Escherichia coli K-12) NP_308412.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate NP_308413.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity NP_308414.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C NP_308415.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent NP_308416.1 similar to CODB_ECOLI gi|1786530 (conserved in Escherichia coli K-12) NP_308417.1 Catalyzes the deamination of cytosine to uracil and ammonia NP_308418.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source NP_308419.1 similar to CYNT_ECOLI gi|1786534 (conserved in Escherichia coli K-12) NP_308420.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide NP_308421.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential NP_308422.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown NP_308423.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments NP_308424.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon NP_308425.2 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer NP_308426.1 similar to araC-family transcriptional regulators e.g. AdpA [Streptomyces coelicolor A3(2)] gi|7544056|emb|CAB87229.1 NP_308427.1 similar to YDDR_BACSU gi|7474951|pir||H69776 NP_308428.1 activator of 3-phenylpropionic acid catabolism NP_308429.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate NP_308430.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase NP_308431.2 similar to MHPC_ECOLI gi|1786545 (conserved in Escherichia coli K-12) NP_308432.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid NP_308433.1 catalyzes the formation of acetyl-CoA from acetalaldehyde NP_308434.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate NP_308435.2 similar to MHPT_ECOLI gi|1786549 (conserved in Escherichia coli K-12) NP_308436.2 similar to YAIL_ECOLI gi|1786550 (conserved in Escherichia coli K-12) NP_308437.1 similar to YAIM_ECOLI gi|1786551 (conserved in Escherichia coli K-12) NP_308438.1 similar to ADHC_ECOLI gi|1786552 (conserved in Escherichia coli K-12) NP_308439.3 formaldehyde-induced negative regulator of the frmRAB operon NP_308440.2 Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import NP_308441.1 similar to ferric transport system permeases e.g. AfuB [Actinobacillus pleuropneumoniae] gi|7387527|sp|Q44123|AFUB_ACTPL NP_308442.1 similar to periplasmic-iron-binding proteins e.g. AfuA [Actinobacillus pleuropneumoniae] gi|1469286|gb|AAB05032.1 NP_308443.1 similar to hexosephosphate transport system regulatory proteins e.g. UhpC [Escherichia coli K-12] gi|136770|sp|P09836|UHPC_ECOLI NP_308444.1 similar to sensor protein kinases e.g. hexosephosphate transport system sensor protein UhpB [Escherichia coli K-12] gi|7429062|pir||RGECUB NP_308445.1 response regulator; similar to transcription regulators e.g. hexose phosphate transport system regulatory protein UhpA [Salmonella typhimurium] gi|136767|sp|P27667|UHPA_SALTY NP_308446.1 with TauB and TauC is responsible for taurine uptake. NP_308447.1 Part of the ABC transporter complex tauABC involved in taurine import NP_308448.1 similar to TAUC_ECOLI gi|1786564 (conserved in Escherichia coli K-12) NP_308449.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers NP_308450.2 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_308451.1 similar to YAIT_ECOLI gi|1786569 (conserved in Escherichia coli K-12) NP_308452.1 similar to YAIV_ECOLI gi|1786573 (conserved in Escherichia coli K-12) NP_308453.1 this protein has no known enzymatic function NP_308454.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope NP_308455.1 similar to YAIW_ECOLI gi|1786576 (conserved in Escherichia coli K-12) NP_308456.1 similar to B0379_ECOLI gi|1786577 (conserved in Escherichia coli K-12) NP_308457.1 similar to B0380_ECOLI gi|1786578 (conserved in Escherichia coli K-12) NP_308458.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli NP_308459.1 similar to YAIB_ECOLI gi|1786581 (conserved in Escherichia coli K-12) NP_308460.1 similar to PHOA_ECOLI gi|1786582 (conserved in Escherichia coli K-12) NP_308461.1 similar to PSIF_ECOLI gi|1786583 (conserved in Escherichia coli K-12) NP_308462.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis NP_308463.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate NP_308464.2 similar to YAII_ECOLI gi|1786586 (conserved in Escherichia coli K-12) NP_308465.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_308466.1 similar to YAIA_ECOLI gi|1786588 (conserved in Escherichia coli K-12) NP_308467.1 similar to AROM_ECOLI gi|1786589 (conserved in Escherichia coli K-12) NP_308468.1 similar to YAIE_ECOLI gi|1786590 (conserved in Escherichia coli K-12) NP_308469.1 similar to B0392_ECOLI gi|1786591 (conserved in Escherichia coli K-12) NP_308471.1 Required for efficient pilin antigenic variation NP_308472.2 catalyzes phosphorylation of fructose; cytosolic enzyme NP_308473.2 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers NP_308474.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity NP_308475.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity NP_308476.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB NP_308477.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB NP_308478.1 similar to BRNQ_ECOLI gi|1786601 (conserved in Escherichia coli K-12) NP_308479.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation NP_308480.1 similar to MALZ_ECOLI gi|1786604 (conserved in Escherichia coli K-12) NP_308482.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP NP_308483.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step NP_308484.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) NP_308485.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex NP_308486.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane NP_308487.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF NP_308488.1 similar to hypothetical protein [Yersinia enterocolitica] gi|3511032|gb|AAC33681.1 NP_308489.1 similar to hypothetical protein [Yersinia pestis] gi|3822096|gb|AAC69816.1 NP_308490.1 similar to YAJD_ECOLI gi|1786611 (conserved in Escherichia coli K-12) NP_308491.1 similar to TSX_ECOLI gi|1786612 (conserved in Escherichia coli K-12) NP_308492.2 similar to YAJI_ECOLI gi|1786613 (conserved in Escherichia coli K-12) NP_308493.1 similar to YBAD_ECOLI gi|1786615 (conserved in Escherichia coli K-12) NP_308494.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil NP_308495.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_308496.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_308497.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP NP_308498.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate NP_308500.1 similar to YJAO_ECOLI gi|1786621 (conserved in Escherichia coli K-12) NP_308501.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_308502.1 similar to ISPA_ECOLI gi|1786623 (conserved in Escherichia coli K-12) NP_308503.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_308504.1 Required for the synthesis of the thiazole moiety NP_308505.2 similar to THIJ_ECOLI gi|1786626 (conserved in Escherichia coli K-12) NP_308506.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis NP_308507.2 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription NP_308508.2 similar to YAJR_ECOLI gi|1786630 (conserved in Escherichia coli K-12) NP_308509.1 converts protoheme IX and farnesyl diphosphate to heme O NP_308510.1 similar to CYOD_ECOLI gi|1786632 (conserved in Escherichia coli K-12) NP_308511.1 similar to CYOC_ECOLI gi|1786633 (conserved in Escherichia coli K-12) NP_308512.1 similar to CYOB_ECOLI gi|1786634 (conserved in Escherichia coli K-12) NP_308513.1 similar to CYOA_ECOLI gi|1786635 (conserved in Escherichia coli K-12) NP_308514.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein NP_308515.2 similar to YAJG_ECOLI gi|1786637 (conserved in Escherichia coli K-12) NP_308516.2 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress NP_308517.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_308518.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_308519.1 binds and unfolds substrates as part of the ClpXP protease NP_308520.1 similar to LON_ECOLI gi|1786643 (conserved in Escherichia coli K-12) NP_308521.1 histone-like DNA-binding protein NP_308522.1 similar to YBAU_ECOLI gi|1786645 (conserved in Escherichia coli K-12) NP_308523.1 similar to YBAV_ECOLI gi|1786646 (conserved in Escherichia coli K-12) NP_308524.1 similar to YBAW_ECOLI gi|1786647 (conserved in Escherichia coli K-12) NP_308525.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His NP_308526.1 similar to YBAE_ECOLI gi|1786650 (conserved in Escherichia coli K-12) NP_308527.1 similar to COF_ECOLI gi|1786651 (conserved in Escherichia coli K-12) NP_308528.2 similar to YBAO_ECOLI gi|1786652 (conserved in Escherichia coli K-12) NP_308529.1 similar to MDLA_ECOLI gi|1786653 (conserved in Escherichia coli K-12) NP_308530.1 similar to MDLB_ECOLI gi|1786654 (conserved in Escherichia coli K-12) NP_308531.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. NP_308532.1 similar to AMTB_ECOLI gi|1786656 (conserved in Escherichia coli K-12) NP_308533.1 similar to TESB_ECOLI gi|1786657 (conserved in Escherichia coli K-12) NP_308534.2 similar to YBAY_ECOLI gi|1786658 (conserved in Escherichia coli K-12) NP_308535.1 similar to YBAZ_ECOLI gi|1786659 (conserved in Escherichia coli K-12) NP_308536.1 similar to YBAA_ECOLI gi|1786661 (conserved in Escherichia coli K-12) NP_308537.1 similar to YLAB_ECOLI gi|1786662 (conserved in Escherichia coli K-12) NP_308538.2 similar to YLAC_ECOLI gi|1786663 (conserved in Escherichia coli K-12) NP_308539.1 similar to YLAD_ECOLI gi|1786664 (conserved in Escherichia coli K-12) NP_308540.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins NP_308541.1 similar to YBAJ_ECOLI gi|1786666 (conserved in Escherichia coli K-12) NP_308542.1 similar to ACRB_ECOLI gi|1786667 (conserved in Escherichia coli K-12) NP_308543.1 similar to ACRA_ECOLI gi|1786668 (conserved in Escherichia coli K-12) NP_308544.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine NP_308545.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS NP_308546.1 similar to YBAM_ECOLI GI:1786672 (conserved in Escherichia coli K-12) NP_308547.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks NP_308548.1 gene 58; similar to YBAN_ECOLI gi|1786674 (conserved in Escherichia coli K-12) NP_308549.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis NP_308550.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_308551.1 similar to YBAB_ECOLI gi|1786677 (conserved in Escherichia coli K-12) NP_308552.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_308553.1 molecular chaperone NP_308554.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_308555.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_308556.1 similar to YBAC_ECOLI gi|1786682 (conserved in Escherichia coli K-12) NP_308557.1 similar to GSK_ECOLI gi|1786684 (conserved in Escherichia coli K-12) NP_308558.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein NP_308559.1 similar to FSR_ECOLI gi|1786686 (conserved in Escherichia coli K-12) NP_308560.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides NP_308561.1 similar to YBAK_ECOLI gi|1786688 (conserved in Escherichia coli K-12) NP_308562.1 similar to YBAP_ECOLI gi|1786689 (conserved in Escherichia coli K-12) NP_308563.1 similar to YBAQ_ECOLI gi|1786690 (conserved in Escherichia coli K-12) NP_308564.1 similar to COPA_ECOLI gi|2493016 (conserved in Escherichia coli K-12) NP_308565.1 catalyzes the formation of glutamate from glutamine NP_308566.1 similar to YBAT_ECOLI gi|1786694 (conserved in Escherichia coli K-12) NP_308567.1 similar to outer membrane transport proteins e.g. CyaE protein [Bordetella pertussis] gi|117799|sp|P11092|CYAE_BORPE NP_308568.1 similar to hypothetical protein [Synechocystis sp. strain PCC 6803] gi|7469433|pir||S76109; similar toRTX protein [Aeromonas salmonicida] gi|6752871|gb|AAF27914.1|AF218037_1 NP_308569.1 similar to hypothetical protein [Synechocystis sp. strain PCC 6803] gi|7469433|pir||S76109; , similar to RTX protein [Aeromonas salmonicida] gi|6752871|gb|AAF27914.1|AF218037_1 NP_308570.1 similar to transporters (ATP-binding proteins) e.g. LktB [Actinobacillus actinomycetemcomitans] gi|126357|sp|P23702|HLYB_ACTAC NP_308571.1 similar to membrane fusion proteins e.g. [Sinorhizobium meliloti] gi|4689001|emb|CAB41456.1| NP_308572.1 activator of copper-responsive regulon genes NP_308575.1 similar to adhesin/invasin [Neisseria meningitidis MC58] gi|7227256|gb|AAF42321.1|, surface protein [Xylella fastidiosa] gi|9106565|gb|AAF84338.1|AE003982_11 NP_308578.1 similar to YBBJ_ECOLI gi|1786696 (conserved in Escherichia coli K-12) NP_308579.1 similar to YBBK_ECOLI gi|1786697 (conserved in Escherichia coli K-12) NP_308580.1 similar to YBBL_ECOLI gi|1786698 (conserved in Escherichia coli K-12) NP_308581.2 similar to YBBM_ECOLI gi|1786699 (conserved in Escherichia coli K-12) NP_308582.2 similar to YBBN_ECOLI gi|1786700 (conserved in Escherichia coli K-12) NP_308583.1 similar to YBBO_ECOLI gi|1786701 (conserved in Escherichia coli K-12) NP_308584.1 similar to TESA_ECOLI gi|1786702 (conserved in Escherichia coli K-12) NP_308585.1 similar to YBBA_ECOLI gi|1786703 (conserved in Escherichia coli K-12) NP_308586.1 similar to YBBP_ECOLI gi|1786704 (conserved in Escherichia coli K-12) NP_308587.1 core protein with extension; similar to RHSD_ECOLI gi|1786706; similar to B0499_ECOLI gi|1786708; Rhs protein NP_308588.1 similar to YBBD_ECOLI gi|1786709 (conserved in Escherichia coli K-12) NP_308590.2 similar to B0502_ECOLI gi|1786711 (conserved in Escherichia coli K-12) NP_308591.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA NP_308592.1 activator of the allDC-ylbA operon involved in allantoin utilization NP_308593.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate NP_308594.1 regulates operons involved in the utilization of allantoin NP_308595.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate NP_308596.1 similar to HYI_ECOLI gi|232160 (conserved in Escherichia coli K-12) NP_308597.1 similar to GLXR_ECOLI gi|2494062 (conserved in Escherichia coli K-12) NP_308598.1 similar to YBBV_ECOLI gi|1786720 (conserved in Escherichia coli K-12) NP_308599.1 similar to YBBW_ECOLI gi|1786721 (conserved in Escherichia coli K-12) NP_308602.2 similar to YBBY_ECOLI gi|1786723 (conserved in Escherichia coli K-12) NP_308603.1 similar to GLXK_ECOLI gi|2495546 (conserved in Escherichia coli K-12) NP_308604.1 similar to YLBA_ECOLI gi|1786725 (conserved in Escherichia coli K-12) NP_308605.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide NP_308606.1 similar to ALLD_ECOLI gi|2497861 (conserved in Escherichia coli K-12) NP_308607.1 multicopy suppressor of dominant negative ftsH mutations NP_308608.1 similar to YLBE_ECOLI gi|1786730 (conserved in Escherichia coli K-12) NP_308609.1 similar to YLBF_ECOLI gi|1786731 (conserved in Escherichia coli K-12) NP_308610.1 forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate NP_308611.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway NP_308612.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway NP_308613.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine NP_308614.1 similar to PPIB_ECOLI gi|1786736 (conserved in Escherichia coli K-12) NP_308615.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_308616.1 similar to YBCI_ECOLI gi|1786738 (conserved in Escherichia coli K-12) NP_308617.2 similar to YBCJ_ECOLI gi|1786740 (conserved in Escherichia coli K-12) NP_308618.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_308619.2 similar to SFMA_ECOLI gi|1786742 (conserved in Escherichia coli K-12) NP_308620.1 similar to SFMC_ECOLI gi|1786743 (conserved in Escherichia coli K-12) NP_308621.1 similar to SFMD_ECOLI gi|1786744 (conserved in Escherichia coli K-12) NP_308622.1 similar to SFMH_ECOLI gi|1786745 (conserved in Escherichia coli K-12) NP_308623.1 similar to SFMF_ECOLI gi|1786746 (conserved in Escherichia coli K-12) NP_308624.1 activates the production of the major fimbrae protein FimA NP_308625.1 similar to ENVY_ECOLI gi|1786778 (conserved in Escherichia coli K-12); envelope protein NP_308626.1 similar to YBCH_ECOLI gi|1786779 (conserved in Escherichia coli K-12) NP_308627.1 similar to NFRA_ECOLI gi|1786780 (conserved in Escherichia coli K-12) NP_308628.1 similar to NFRB_ECOLI gi|1786781 (conserved in Escherichia coli K-12) NP_308629.1 similar to H repeat-associated protein in RhsB element [Escherichia coli] gi|140772|sp|P28912|YHHI_ECOLI NP_308630.1 Rhs protein; similar to Rhs protein - Streptomyces coelicolor A3(2) gi|7321289|emb|CAB82067.1; similar toRhsE protein - E. coli gi|2507113|sp|P24211| NP_308632.1 Rhs protein; similar to Rhs protein [Streptomyces coelicolor A3(2)] gi|7321289|emb|CAB82067.1; similar toRhsH protein [Escherichia coli strain ec45] gi|2920634|gb|AAC32471.1 NP_308634.1 similar to Vgr proteins e.g. [Escherichia coli strain ec11] gi|2920640|gb|AAC32475.1 NP_308635.1 similar to YBCZ_ECOLI gi|1786783 (conserved in Escherichia coli K-12) NP_308636.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system NP_308637.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver NP_308638.1 similar to YLCC_ECOLI gi|1786786 (conserved in Escherichia coli K-12) NP_308639.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver NP_308640.1 similar to YBDE_ECOLI gi|1786788 (conserved in Escherichia coli K-12) NP_308641.1 similar to PHEP_ECOLI gi|1786789 (conserved in Escherichia coli K-12) NP_308642.1 similar to YBDG_ECOLI gi|1786791 (conserved in Escherichia coli K-12) NP_308643.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive NP_308644.1 similar to YBDF_ECOLI gi|1786793 (conserved in Escherichia coli K-12) NP_308645.1 similar to YBDJ_ECOLI gi|1786794 (conserved in Escherichia coli K-12) NP_308646.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity NP_308647.1 similar to YBDY_ECOLI gi|3025009|sp|P77091 (conserved in Escherichia coli K-12) NP_308648.1 similar to hypothetical protein in cspA-glyS intergenic region [Escherichia coli] gi|3025009|sp|P77091 NP_308649.1 similar to ENTD_ECOLI gi|1786797 (conserved in Escherichia coli K-12) NP_308650.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space NP_308651.1 similar to FES_ECOLI gi|1786799 (conserved in Escherichia coli K-12) NP_308652.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin NP_308653.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake NP_308654.1 with FepBDE is involved in the transport of ferric enterobactin NP_308655.1 with FepBCD is involved in the transport of ferric enterobactin NP_308656.1 with FepBCG is involved in the transport of ferric enterobactin NP_308657.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters NP_308658.1 with FepCDG is involved in the transport of ferric enterobactin NP_308659.1 synthesizes isochorismate acid from chorismate NP_308660.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate NP_308661.1 similar to ENTB_ECOLI gi|1786811 (conserved in Escherichia coli K-12) NP_308662.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin NP_308663.1 similar to YBDB_ECOLI gi|1786813 (conserved in Escherichia coli K-12) NP_308664.1 similar to CSTA_ECOLI gi|1786814 (conserved in Escherichia coli K-12) NP_308665.1 member of the iron-containing alcohol dehydrogenase; unknown function NP_308666.1 catalyzes the transfer of an amino moiety NP_308667.1 similar to YBDM_ECOLI gi|1786817 (conserved in Escherichia coli K-12) NP_308668.1 similar to YBDN_ECOLI gi|1786818 (conserved in Escherichia coli K-12) NP_308669.1 similar to YBDO_ECOLI gi|1786820 (conserved in Escherichia coli K-12) NP_308670.3 Involved in disulfide bond formation NP_308671.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate NP_308672.1 similar to AHPF_ECOLI gi|1786823 (conserved in Escherichia coli K-12) NP_308673.1 similar to YBDQ_ECOLI gi|1786824 (conserved in Escherichia coli K-12) NP_308674.1 similar to YBDR_ECOLI gi|1786825 (conserved in Escherichia coli K-12) NP_308675.1 similar to B0609_ECOLI gi|1786826 (conserved in Escherichia coli K-12) NP_308676.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation NP_308677.1 similar to RNA_ECOLI gi|1786828 (conserved in Escherichia coli K-12) NP_308678.1 similar to YBDS_ECOLI gi|1786829 (conserved in Escherichia coli K-12) NP_308679.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA NP_308680.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate NP_308681.1 similar to CITF_ECOLI gi|1786832 (conserved in Escherichia coli K-12) NP_308682.2 similar to CITE_ECOLI gi|1786833 (conserved in Escherichia coli K-12) NP_308683.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate NP_308684.2 similar to CITC_ECOLI gi|1786835 (conserved in Escherichia coli K-12) NP_308685.1 similar to CITA_ECOLI gi|1786837 (conserved in Escherichia coli K-12) NP_308686.1 regulates the expression of citAB in citrate fermentation NP_308687.1 responsible for the transport of C4-dicarboxylates during anaerobic growth NP_308688.1 catalyzes the transfer of palmitate to lipid A NP_308689.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator NP_308690.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling NP_308691.1 similar to YBEH_ECOLI gi|1786843, YBEM_ECOLI, gi|1786844 NP_308692.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes NP_308693.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_308694.2 similar to YBEF_ECOLI gi|1786847 (conserved in Escherichia coli K-12) NP_308695.2 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein NP_308696.1 similar to YBED_ECOLI gi|1786850 (conserved in Escherichia coli K-12) NP_308697.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors NP_308698.1 similar to RLPA_ECOLI gi|1786852 (conserved in Escherichia coli K-12) NP_308699.1 similar to MRDB_ECOLI gi|1786853 (conserved in Escherichia coli K-12) NP_308700.1 similar to MRDA_ECOLI gi|1786854 (conserved in Escherichia coli K-12) NP_308701.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA NP_308702.2 similar to YBEB_ECOLI gi|1786856 (conserved in Escherichia coli K-12) NP_308703.1 similar to PHPB_ECOLI gi|1786857 (conserved in Escherichia coli K-12); phosphohistidine protein NP_308704.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria NP_308705.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA NP_308706.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane NP_308707.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_308708.1 similar to YBEL_ECOLI gi|1786863 (conserved in Escherichia coli K-12) NP_308709.1 similar to YBEQ_ECOLI gi|1786864 NP_308710.1 similar to YBER_ECOLI gi|1786865 (conserved in Escherichia coli K-12) NP_308711.1 similar to YBES_ECOLI gi|1786866 (conserved in Escherichia coli K-12) NP_308712.1 similar to YBET_ECOLI gi|1786867 (conserved in Escherichia coli K-12) NP_308713.1 similar to YBEU_ECOLI gi|1786868 (conserved in Escherichia coli K-12) NP_308716.1 similar to YBEW_ECOLI gi|1786870 (conserved in Escherichia coli K-12) NP_308717.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific NP_308718.1 similar to GLTL_ECOLI gi|1786872 (conserved in Escherichia coli K-12) NP_308719.1 similar to GLTK_ECOLI gi|1786873 (conserved in Escherichia coli K-12) NP_308720.1 similar to GLTJ_ECOLI gi|1786874 (conserved in Escherichia coli K-12) NP_308721.1 similar to YBEJ_ECOLI gi|1786876 (conserved in Escherichia coli K-12) NP_308722.1 Transfers the fatty acyl group on membrane lipoproteins NP_308723.1 similar to YBEX_ECOLI gi|1786879 (conserved in Escherichia coli K-12) NP_308724.1 similar to YBEY_ECOLI gi|1786880 (conserved in Escherichia coli K-12) NP_308725.1 similar to YBEZ_ECOLI gi|1786881 (conserved in Escherichia coli K-12) NP_308726.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) NP_308727.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q NP_308731.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP NP_308732.1 similar to NAGD_ECOLI gi|1786890 (conserved in Escherichia coli K-12) NP_308733.1 nag repressor; similar to NAGC_ECOLI gi|1786891 (conserved in Escherichia coli K-12) NP_308734.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate NP_308735.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate NP_308736.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_308737.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_308740.1 similar to YBFN_ECOLI gi|1786898 (conserved in Escherichia coli K-12) NP_308741.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer NP_308742.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_308743.1 similar to YBFE_ECOLI gi|1786901 (conserved in Escherichia coli K-12) NP_308744.1 similar to YBFF_ECOLI gi|1786902 (conserved in Escherichia coli K-12) NP_308745.1 negative modulator of the initiation of chromosome replication NP_308746.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate NP_308747.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system NP_308748.1 similar to SPEF_ECOLI gi|1786909 NP_308749.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport NP_308750.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein NP_308751.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex NP_308752.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_308753.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_308754.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions NP_308755.1 similar to YBFA_ECOLI gi|1786916 (conserved in Escherichia coli K-12) NP_308756.1 core protein with extension; similar to RHSC_ECOLI gi|1786917 and B0703_ECOLI gi|1786921; Rhs protein NP_308757.1 similar to YBFC_ECOLI gi|1786922 NP_308758.1 similar to H-repeat assciated proteins e.g. YHHI_ECOLI gi|1789896 (conserved in Escherichia coli K-12) NP_308759.1 similar to YBGA_ECOLI gi|1786925 (conserved in Escherichia coli K-12) NP_308760.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent NP_308761.1 similar to YBGH_ECOLI gi|1786927 (conserved in Escherichia coli K-12) NP_308762.1 similar to YBGI_ECOLI gi|1786928 (conserved in Escherichia coli K-12) NP_308763.1 similar to YBGJ_ECOLI gi|1786929 (conserved in Escherichia coli K-12) NP_308764.1 similar to YBGK_ECOLI gi|1786930 (conserved in Escherichia coli K-12) NP_308765.1 similar to YBGL_ECOLI gi|1786931 (conserved in Escherichia coli K-12) NP_308766.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity NP_308767.1 similar to ABRB_ECOLI gi|1786933 (conserved in Escherichia coli K-12) NP_308768.1 similar to YBGO_ECOLI gi|1786935 NP_308769.1 similar to YBGP_ECOLI gi|1786936 NP_308770.1 similar to YBGQ_ECOLI gi|1786937; truncated due to frameshift NP_308771.1 similar to YBGD_ECOLI gi|1786938 NP_308772.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH NP_308773.1 similar to SDHC_ECOLI gi|1786940 (conserved in Escherichia coli K-12) NP_308774.1 similar to SDHD_ECOLI gi|1786941 (conserved in Escherichia coli K-12) NP_308775.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_308776.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase NP_308777.1 similar to B0725_ECOLI gi|1786944 (conserved in Escherichia coli K-12) NP_308778.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide NP_308779.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA NP_308780.1 catalyzes the interconversion of succinyl-CoA and succinate NP_308781.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_308782.1 similar to transcriptional regulators e.g. glycine cleavage system transcription activator (gcv operon activator) - Escherichia coli gi|417043|sp|P32064|GCVA_ECOLI NP_308783.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide NP_308784.1 similar to fumarate hydratase class I, aerobic (fumarase) - Escherichia coli gi|120598|sp|P00923|FUMA_ECOLI NP_308785.1 similar to glutamate/aspartate transport proteins (proton glutamate symport proteins) e.g. [Bacillus stearothermophilus] gi|121467|sp|P24943|GLTT_BACST; similar toC4-dicarboxylate transporter NP_308788.1 beta-methylaspartase; similar to 3-methylaspartate ammonia-lyases (beta-methylaspartases) e.g. [Citrobacter amalonaticus] gi|3184397|dbj|BAA28709.1|; [Clostridium tetanomorphum] gi|729971|sp NP_308789.1 methylaspartate mutase E; similar to glutamate mutases e.g. [Citrobacter amalonaticus] gi|3184396|dbj|BAA28708.1|; [Clostridium tetanomorphum] gi|729586|sp|Q05509|GLME_CLOTT NP_308790.1 methylaspartate mutase L; similar to glutamate mutase L (methylaspartate mutase L) e.g. [Clostridium tetanomorphum] gi|444421|prf||1907157C NP_308791.1 converts methylaspartate to L-glutamate NP_308795.1 similar to CYDA_ECOLI gi|1786953 (conserved in Escherichia coli K-12) NP_308796.1 similar to CYDB_ECOLI gi|1786954 (conserved in Escherichia coli K-12) NP_308797.1 similar to YBGE_ECOLI gi|1786956 (conserved in Escherichia coli K-12) NP_308798.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components NP_308799.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins NP_308800.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins NP_308801.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins NP_308802.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA NP_308803.1 similar to PAL_ECOLI gi|1786962 (conserved in Escherichia coli K-12) NP_308804.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity NP_308805.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate NP_308806.1 similar to PNUC_ECOLI gi|1786965 (conserved in Escherichia coli K-12) NP_308807.1 involved in zinc efflux across the cytoplasmic membrane NP_308808.1 similar to B0753_ECOLI gi|1786968 (conserved in Escherichia coli K-12) NP_308809.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive NP_308810.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_308811.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose NP_308812.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism NP_308813.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P NP_308814.2 similar to GALE_ECOLI gi|1786974 (conserved in Escherichia coli K-12) NP_308815.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum NP_308816.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons NP_308817.1 similar to B0762_ECOLI gi|1786977 (conserved in Escherichia coli K-12) NP_308818.1 with ModCB is involved in the high-affinity transport of molybdate NP_308819.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE NP_308820.1 Part of the ABC transporter complex modABC involved in molybdenum import NP_308821.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily NP_308822.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate NP_308823.2 similar to YBHD_ECOLI gi|1786984 (conserved in Escherichia coli K-12) NP_308824.1 similar to YBHH_ECOLI gi|1786985 (conserved in Escherichia coli K-12) NP_308825.1 similar to YBHI_ECOLI gi|1786986 (conserved in Escherichia coli K-12) NP_308826.2 similar to YBHJ_ECOLI gi|1786987 (conserved in Escherichia coli K-12) NP_308827.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase NP_308828.1 similar to excisionase [Bacteriophage HK022] gi|1722835|sp|P11683|VXIS_BP434 and [Bacteriophage lambda] gi|139680|sp|P03699|VXIS_LAMBD NP_308829.1 similar to hypothetical protein ORF55 [Bacteriophage 434] gi|801889|gb|AAA67903.1 NP_308832.1 similar to C4-type zinc finger proteins (TraR family) e.g. gi|7649830|dbj|BAA94108.1 NP_308834.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881603|dbj|BAA84294.1, orf63 [Bacteriophage lambda] gi|508994|gb|AAA96567.1 NP_308835.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585389|gb|AAD25417.1|AF125520_12, orf60a [Bacteriophage lambda] gi|508995|gb|AAA96568.1 NP_308836.1 similar to exonucleases e.g. [Bacteriophage lambda] gi|119702|sp|P03697|EXO_LAMBD NP_308837.1 similar to NinE [Bacteriophage 21] gi|4539480|emb|CAB39989.1 NP_308838.1 similar to NinF [Bacteriophage 21] gi|4539481|emb|CAB39990.1| NP_308839.1 similar to NinG [Bacteriophage 21] gi|4539482|emb|CAB39991.1 NP_308840.1 similar to serine/threonin protein phosphatases e.g. [Bacteriophage lambda] gi|130792|sp|P03772|PP_LAMBD NP_308841.1 similar to probable outer membrane protein [Helicobacter pylori (strain J99)] gi|7465285|pir||H71907 NP_308842.1 similar to antiterminators e.g. protein Q [Bacteriophage 82] gi|132277|sp|P13870|REGQ_BP82 NP_308843.2 similar to orf14 [Actinobacillus actinomycetemcomitans] gi|7592819|dbj|BAA94406.1, TfpB protein [Moraxella bovis] gi|141258|sp|P20666|TFPB_MORBO NP_308845.1 similar to holin S e .g. [Bacteriophage 933W] gi|4499808|emb|CAB39307.1 NP_308846.1 lysozyme; similar to endolysins (lysozyme) e.g. R protein [Bacteriophage 21] gi|67436|pir||LZBP21 NP_308847.1 similar to hypothetical protein gp15 [Bacteriophage PS119] gi|3676087|emb|CAA09711.1, endopeptidases e.g. [Bacteriophage lambda] gi|67522|pir||APBPML ident NP_308852.1 similar to terminase large subunits e.g. [Bacteriophage WO] gi|6723224|dbj|BAA89621.1, [Bacteriophage N15] gi|7444579|pir||T13088 NP_308854.1 similar to portal protein [Wolbachia sp. wKue]gi|6723246|dbj|BAA89642.1| NP_308856.1 similar to scaffolding protein [Streptococcus thermophilus bacteriophage DT1] gi|4530143|gb|AAD21883.1, probable protease/scaffold protein, ClpP protease e.g. [Bacteriophage D3] gi|5059251|gb|AAD38956.1 NP_308859.1 similar to minor tail proteins e.g. protein Z [Bacteriophage N15] gi|7521219|pir||T13097, GpZ [Bacteriophage lambda] gi|138849|sp|P03731|VMTZ_LAMBD NP_308860.1 similar to minor tail proteins e.g. protein U [Bacteriophage N15] gi|7444588|pir||T13098, GpU [Bacteriophage lambda] gi|138847|sp|P03732|VMTU_LAMBD NP_308861.1 similar to major tail proteins e.g. protein V [Bacteriophage N15] gi|7444589|pir||T13099, GpV [Bacteriophage lambda] gi|138848|sp|P03733|VMTV_LAMBD NP_308862.1 similar to minor tail proteins e.g. GpG [Bacteriophage lambda] gi|138842|sp|P03734|VMTG_LAMBD NP_308863.1 similar to minor tail proteins e.g. GpT [Bacteriophage lambda] gi|138846|sp|P03735|VMTT_LAMBD; may be produced by translational frameshift NP_308864.1 similar to tail length tape measure protein precursors e.g. GpH [Bacteriophage lambda] gi|138843|sp|P03736|VMTH_LAMBD NP_308865.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_308866.1 similar to GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_308867.1 similar to GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_308868.1 similar to GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_308869.1 similar to GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_308870.1 similar to outer membrane protein Lom precursors e.g. [prophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2 NP_308871.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_308872.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_308873.1 similar to hypothetical protein [Salmonella typhimurium LT2] gi|6960367|gb|AAF33527.1 NP_308878.1 YbhB; similar to rat and human kinase inhibitory proteins NP_308879.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate NP_308880.1 similar to BIOB_ECOLI gi|1786992 (conserved in Escherichia coli K-12) NP_308881.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine NP_308882.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth NP_308883.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_308884.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_308885.1 similar to YBHK_ECOLI gi|1786997 (conserved in Escherichia coli K-12) NP_308886.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z NP_308887.1 similar to MOAB_ECOLI gi|1787000 (conserved in Escherichia coli K-12) NP_308888.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis NP_308889.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin NP_308890.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin NP_308891.1 similar to YBHL_ECOLI gi|1787004 (conserved in Escherichia coli K-12) NP_308892.1 similar to YBHM_ECOLI gi|1787005 (conserved in Escherichia coli K-12) NP_308893.1 similar to YBHN_ECOLI gi|1787006 (conserved in Escherichia coli K-12) NP_308894.1 similar to YBHO_ECOLI gi|1787007 (conserved in Escherichia coli K-12) NP_308895.1 similar to YBHP_ECOLI gi|1787008 (conserved in Escherichia coli K-12) NP_308896.1 similar to YBHQ_ECOLI gi|1787009 (conserved in Escherichia coli K-12) NP_308897.1 similar to YBHR_ECOLI gi|1787010 (conserved in Escherichia coli K-12) NP_308898.1 similar to YBHS_ECOLI gi|1787011 (conserved in Escherichia coli K-12) NP_308899.2 similar to YBHF_ECOLI gi|1787012 (conserved in Escherichia coli K-12) NP_308900.1 similar to B0795_ECOLI gi|1787013 (conserved in Escherichia coli K-12) NP_308901.1 similar to YBIH_ECOLI gi|1787014 (conserved in Escherichia coli K-12) NP_308902.1 this helicase is not essential cell growth NP_308903.1 similar to secreted effector protein SopA [Salmonella dublin] gi|5669806|gb|AAD46479.1|AF121227_1 and YjBI [Escherichia coli] gi|418540|sp|P32690|YJBI_ECOLI NP_308904.1 helicase involved in DNA repair and perhaps also replication NP_308905.1 similar to YBIB_ECOLI gi|1787019 (conserved in Escherichia coli K-12) NP_308906.1 similar to YBIC_ECOLI gi|1787020 (conserved in Escherichia coli K-12) NP_308907.1 similar to YBIJ_ECOLI gi|1787021 (conserved in Escherichia coli K-12) NP_308908.1 similar to YBII_ECOLI gi|1787022 (conserved in Escherichia coli K-12) NP_308909.2 similar to YBIX_ECOLI gi|1787023 (conserved in Escherichia coli K-12) NP_308910.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein NP_308911.1 similar to YBIM_ECOLI gi|1787026 (conserved in Escherichia coli K-12) NP_308912.1 similar to YBIN_ECOLI gi|1787027 (conserved in Escherichia coli K-12) NP_308913.1 similar to YBIO_ECOLI gi|1787028 (conserved in Escherichia coli K-12) NP_308914.1 similar to ATP-binding component of ABC transporters NP_308915.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine NP_308916.1 similar to periplasmic-binding component of ABC transporters NP_308917.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage NP_308918.1 similar to YBIF_ECOLI gi|1787033 (conserved in Escherichia coli K-12) NP_308919.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains NP_308920.1 similar to YBIP_ECOLI gi|1787035 (conserved in Escherichia coli K-12) NP_308921.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present NP_308922.1 similar to YBIR_ECOLI gi|1787039 (conserved in Escherichia coli K-12) NP_308923.1 similar to YBIS_ECOLI gi|1787040 (conserved in Escherichia coli K-12) NP_308924.1 similar to YBIT_ECOLI gi|1787041 (conserved in Escherichia coli K-12) NP_308925.1 similar to YBIU_ECOLI gi|1787042 (conserved in Escherichia coli K-12) NP_308926.1 similar to B0822_ECOLI gi|1787043 (conserved in Escherichia coli K-12) NP_308929.1 similar to YBIY_ECOLI gi|1787045 (conserved in Escherichia coli K-12) NP_308930.3 similar to transaldolase from Escherichia coli; many organisms have multiple copies NP_308931.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase NP_308932.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum NP_308935.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains NP_308936.1 similar to B0830_ECOLI gi|1787052 (conserved in Escherichia coli K-12) NP_308937.1 similar to B0831_ECOLI gi|1787053 (conserved in Escherichia coli K-12) NP_308938.1 similar to B0832_ECOLI gi|1787054 (conserved in Escherichia coli K-12) NP_308939.1 similar to B0833_ECOLI gi|1787055 (conserved in Escherichia coli K-12) NP_308940.1 similar to B0834_ECOLI gi|1787056 (conserved in Escherichia coli K-12) NP_308942.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit NP_308943.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing NP_308944.1 similar to YLII_ECOLI gi|1787060 (conserved in Escherichia coli K-12) NP_308945.2 similar to YLIJ_ECOLI gi|1787061 (conserved in Escherichia coli K-12) NP_308946.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains NP_308947.1 similar to DEOR_ECOLI gi|1787063 (conserved in Escherichia coli K-12) NP_308948.1 similar to YBJG_ECOLI gi|1787064 (conserved in Escherichia coli K-12) NP_308949.1 similar to CMR_ECOLI gi|1787065 (conserved in Escherichia coli K-12) NP_308950.1 similar to YBJH_ECOLI gi|1787066 (conserved in Escherichia coli K-12) NP_308951.2 similar to B0844_ECOLI gi|1787067 (conserved in Escherichia coli K-12) NP_308952.1 similar to B0845_ECOLI gi|1787068 (conserved in Escherichia coli K-12) NP_308953.1 similar to B0846_ECOLI gi|1787069 (conserved in Escherichia coli K-12) NP_308954.1 similar to B0847_ECOLI gi|1787071 (conserved in Escherichia coli K-12) NP_308955.1 similar to YBJM_ECOLI gi|1787072 (conserved in Escherichia coli K-12) NP_308956.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase NP_308957.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function NP_308958.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds NP_308959.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 NP_308960.1 similar to YBJN_ECOLI gi|1787077 (conserved in Escherichia coli K-12) NP_308961.1 similar to POTF_ECOLI gi|1787078 (conserved in Escherichia coli K-12) NP_308962.1 part of the PotFGHI ATP-dependent putrescine transporter NP_308963.1 similar to POTH_ECOLI gi|1787080 (conserved in Escherichia coli K-12) NP_308964.1 similar to POTI_ECOLI gi|1787081 (conserved in Escherichia coli K-12) NP_308965.1 similar to YBJO_ECOLI gi|1787082 (conserved in Escherichia coli K-12) NP_308966.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA NP_308967.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_308968.1 similar to phosphotransferase system enzymes IIB e.g. [Escherichia coli] gi|732028|sp|P39302|PTXB_ECOLI NP_308970.1 similar to ARTJ_ECOLI gi|1787085 (conserved in Escherichia coli K-12) NP_308971.1 with ArtPQJI acts to transport arginine across the inner membrane NP_308972.1 with ArtPMJI transports arginine across the inner membrane NP_308973.1 similar to ARTI_ECOLI gi|1787088 (conserved in Escherichia coli K-12) NP_308974.1 With ArtMQJI transports arginine across the inner membrane NP_308975.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS NP_308979.1 similar to B0866_ECOLI gi|1787091 (conserved in Escherichia coli K-12) NP_308980.1 similar to B0867_ECOLI gi|1787092 (conserved in Escherichia coli K-12) NP_308981.1 similar to B0868_ECOLI gi|1787093 (conserved in Escherichia coli K-12) NP_308982.1 similar to YBJT_ECOLI gi|1787094 (conserved in Escherichia coli K-12) NP_308983.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine NP_308984.1 catalyzes the formation of acetate from pyruvate NP_308985.1 similar to HCR_ECOLI gi|7387728 (conserved in Escherichia coli K-12) NP_308986.2 catalyzes the reduction of hydroxylamine to ammonia and water NP_308987.1 similar to surface protein YBJE_ECOLI gi|1787100 (conserved in Escherichia coli K-12) NP_308988.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure NP_308989.1 similar to YBJD_ECOLI gi|1787102 (conserved in Escherichia coli K-12) NP_308990.1 similar to YBJX_ECOLI gi|1787103 (conserved in Escherichia coli K-12) NP_308991.2 confers macrolide resistance via active drug efflux NP_308992.1 with MacA is involved in the export of macrolide NP_308993.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible NP_308994.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA NP_308995.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates NP_308996.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_308997.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys NP_308998.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c NP_308999.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c NP_309000.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding NP_309001.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system NP_309002.1 DNA-binding membrane protein required for chromosome resolution and partitioning NP_309003.1 participates with LolB in the incorporation of lipoprotein into the outer membrane NP_309004.1 similar to YCAJ_ECOLI gi|1787119 (conserved in Escherichia coli K-12) NP_309005.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_309006.2 similar to DMSA_ECOLI gi|1787121 (conserved in Escherichia coli K-12) NP_309007.1 similar to DMSB_ECOLI gi|1787122 (conserved in Escherichia coli K-12) NP_309008.1 similar to DMSC_ECOLI gi|1787123 (conserved in Escherichia coli K-12) NP_309009.1 similar to YCAC_ECOLI gi|1787124 (conserved in Escherichia coli K-12) NP_309010.1 similar to YCAD_ECOLI gi|1787126 (conserved in Escherichia coli K-12) NP_309011.1 similar to B0899_ECOLI gi|1787127 (conserved in Escherichia coli K-12) NP_309012.1 activates pyruvate formate-lyase 1 under anaerobic conditions NP_309013.1 similar to PFLB_ECOLI gi|1787131 (conserved in Escherichia coli K-12) NP_309014.1 similar to FOCA_ECOLI gi|1787132 (conserved in Escherichia coli K-12) NP_309015.2 similar to YCAO_ECOLI gi|1787133 (conserved in Escherichia coli K-12) NP_309016.1 similar to YCAP_ECOLI gi|1787135 (conserved in Escherichia coli K-12) NP_309017.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine NP_309018.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_309019.1 similar to YCAL_ECOLI gi|1787138 (conserved in Escherichia coli K-12) NP_309020.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_309021.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_309022.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control NP_309023.2 similar to YCAI_ECOLI gi|1787142 (conserved in Escherichia coli K-12) NP_309024.1 involved in the transport of lipid A across the inner membrane NP_309025.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate NP_309026.1 similar to YCAQ_ECOLI gi|1787145 (conserved in Escherichia coli K-12) NP_309027.1 similar to YCAR_ECOLI gi|1787146 (conserved in Escherichia coli K-12) NP_309028.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS NP_309029.1 similar to B0919_ECOLI gi|1787149 (conserved in Escherichia coli K-12) NP_309030.1 similar to YCBC_ECOLI gi|1787150 (conserved in Escherichia coli K-12) NP_309031.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA NP_309032.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division NP_309033.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division NP_309034.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects NP_309035.1 similar to YCBB_ECOLI gi|1787155 (conserved in Escherichia coli K-12) NP_309036.1 similar to YCBK_ECOLI gi|1787157 (conserved in Escherichia coli K-12) NP_309037.1 similar to YCBL_ECOLI gi|1787158 (conserved in Escherichia coli K-12) NP_309038.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate NP_309039.1 outer membrane porin F; 1a; Ia; b NP_309040.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_309041.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate NP_309042.1 similar to PEPN_ECOLI gi|1787163 (conserved in Escherichia coli K-12) NP_309043.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding protein and SsuC the permease NP_309044.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding protein and SsuC the permease NP_309045.1 catalyzes the release of sulfite from alkanesulfonates NP_309046.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding protein and SsuC the permease NP_309047.1 similar to SSUE_ECOLI gi|2507138 (conserved in Escherichia coli K-12) NP_309048.1 similar to YCBQ_ECOLI gi|1787170 (conserved in Escherichia coli K-12) NP_309049.1 similar to YCBR_ECOLI gi|1787171 (conserved in Escherichia coli K-12) NP_309052.1 similar to Salmonella FimH protein and B0941_ECOLI gi|1787173 (conserved in Escherichia coli K-12) NP_309053.1 similar to fimbrial-like protein B0942_ECOLI gi|1787174 NP_309054.1 similar to B0943_ECOLI gi|1787175 (conserved in Escherichia coli K-12) NP_309055.1 similar to chaperone YCBF_ECOLI gi|1787176 NP_309056.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors NP_309057.2 similar to YCBW_ECOLI gi|1787178 (conserved in Escherichia coli K-12) NP_309058.1 similar to B0947_ECOLI gi|1787179 (conserved in Escherichia coli K-12) NP_309059.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA NP_309060.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth NP_309061.1 similar to PQIA_ECOLI gi|1787183 (conserved in Escherichia coli K-12) NP_309062.1 similar to PQIB_ECOLI gi|1787184 (conserved in Escherichia coli K-12) NP_309063.1 similar to YMBA_ECOLI gi|1787185 (conserved in Escherichia coli K-12) NP_309064.1 similar to RMF_ECOLI gi|1787186 (conserved in Escherichia coli K-12) NP_309065.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP NP_309066.1 similar to B0955_ECOLI gi|1787188 (conserved in Escherichia coli K-12) NP_309067.1 similar to YCBG_ECOLI gi|1787190 (conserved in Escherichia coli K-12) NP_309068.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d NP_309069.1 similar to SULA_ECOLI gi|1787192 (conserved in Escherichia coli K-12) NP_309070.1 similar to B0959_ECOLI gi|1787193 (conserved in Escherichia coli K-12) NP_309071.1 similar to B0960_ECOLI gi|1787194 (conserved in Escherichia coli K-12) NP_309072.1 similar to YCCF_ECOLI gi|1787195 (conserved in Escherichia coli K-12) NP_309073.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand NP_309074.2 catalyzes the formation of methylglyoxal from glycerone phosphate NP_309075.1 similar to B0964_ECOLI gi|1787198 (conserved in Escherichia coli K-12) NP_309076.1 similar to B0965_ECOLI gi|1787199 (conserved in Escherichia coli K-12) NP_309077.2 similar to YCCV_ECOLI gi|1787200 (conserved in Escherichia coli K-12) NP_309078.2 similar to B0967_ECOLI gi|1787201 (conserved in Escherichia coli K-12) NP_309079.1 catalyzes the hydrolysis of acylphosphate NP_309080.2 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs NP_309081.1 similar to YCCA_ECOLI gi|1787205 (conserved in Escherichia coli K-12) NP_309082.1 similar to integrase [Bacteriophage HK022] gi|138560|sp|P16407|VINT_BPHK0 NP_309085.1 similar to YdfD [Escherichia coli] gi|140587|sp|P29010|YDFD_ECOLI NP_309086.1 similar to dicB [Escherichia coli] gi|2507009|sp|P09557|DICB_ECOLI NP_309092.1 similar to YdfA [Escherichia coli] gi|140584|sp|P29008|YDFA_ECOLI NP_309094.1 similar to yacB [Plasmid ColIb-P9] gi|4512441|dbj|BAA75090.1 NP_309096.2 similar to probable regulatory protein [Salmonella typhimurium] gi|7467281|pir||T03008; similar toDicA [Escherichia coli] gi|118631|sp|P06966|DICA_ECOLI NP_309098.1 similar to YdaT [Escherichia coli] gi|3025103|sp|P76064|YDAT_ECOLI NP_309101.1 acts to load the DnaB helicase onto the intiation site durning DNA replication NP_309102.1 similar to gi|3025105|sp|P76066|YDAW_ECOLI NP_309104.1 similar to hypothetical proteins e.g. IroE [Salmonella enterica] gi|2738251|gb|AAC46182.1 NP_309107.1 similar to Hok/Gef family e.g. MokW [Bacteriophage 933W] AAD25481.1 NP_309108.1 similar to QD1 [Bacteriophage N15] gi|2564084|gb|AAB81659.1 NP_309110.1 similar to Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1; similar tocrossover junction endodeoxyribonuclease Rus [Escherichia coli cryptic prophage DLP12] gi|2 NP_309111.1 similar to bacteriophage antitermination proteins e.g. YbcQ [Escherichia coli cryptic prophage DLP12 gi|4585416|gb|AAD25444.1|AF125520_39 NP_309112.1 similar to YpbD [Bacillus subtilis] gi|1730886|sp|P50730|YPBD_BACSU NP_309114.1 similar to transcriptional regulators e.g. YhiW [Escherichia coli] gi|586679|sp|P37638|YHIW_ECOLI NP_309115.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_309116.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_309117.1 OrfB protein of insertion sequence IS629; similar to transposases e.g. [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_309119.1 similar to endopeptidases e.g. [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1 NP_309123.1 similar to endolysins e.g. [Bacteriophage H-19B] gi|4335686|gb|AAD17382.1 NP_309127.1 similar to holin [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1 NP_309129.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli O157:H7 strain EDL933] gi|3414881|gb|AAC31492.1 NP_309130.1 similar to hypothetical proteins e.g. L0014 [Escherichia coli O157:H7 strain EDL933] gi|3414882|gb|AAC31493.1 NP_309131.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1 NP_309133.1 similar to terminase large subunit [Bacteriophage 21] gi|2851579|sp|P36693|TERL_BPP21 NP_309134.1 similar to portal proteins e.g. GP4 [Bacteriophage P21] gi|549295|sp|P36272|VG04_BPP21 NP_309135.1 similar to head-tail preconnector proteins e.g. Gp5 [Bacteriophage P21] gi|549296|sp|P36273|VG05_BPP21 NP_309136.1 similar to head decoration proteins e.g. Gpshp [Bacteriophage P21] gi|549437|sp|P36275|VSHP_BPP21 NP_309137.1 similar to N-terminal parts of major head proteins e.g. Gp7 [Bacteriophage P21] gi|547612|sp|P36270|HEAD_BPP21 NP_309139.2 similar to minor tail proteins e.g. GpG [Bacteriophage lambda] gi|138842|sp|P03734|VMTG_LAMBD NP_309140.1 similar to minor tail proteins GpG-T [Bacteriophage lambda] gi|7429179|pir||TLBPTL; probably produced by translational frameshift NP_309141.1 tail length determinator; similar to tail length tape measure proteins e.g. GpH [Bacteriophage lambda] gi|138843|sp|P03736|VMTH_LAMBD NP_309142.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_309143.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_309144.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_309145.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_309147.1 similar to copper/zinc-superoxide dismutases e.g. [Salmonella typhimurium] gi|2462699|emb|CAA73588.1 NP_309148.1 similar to host specificity proteins e.g. GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_309149.1 similar to Lom outer membrane proteins e.g. [prophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2 NP_309150.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_309151.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60; similar to tail protein of 933W gi|4585436|gb|AAD25464.1|AF125520_59 NP_309152.1 probable secreted effector protein; similar to EspF proteins e.g. [Escherichia coli strain E2348/69] gi|2865308|gb|AAC38400.1; similar toL0016 - Escherichia coli gi|3414884|gb|AAC31495.1 NP_309154.1 similar to avirulence protein A [Pseudomonas syringae] gi|114726|sp|P11437|AVRA_PSESG NP_309155.1 similar to HYAA_ECOLI gi|1787206 (conserved in Escherichia coli K-12) NP_309156.1 involved in hydrogen cycling during fermentative growth NP_309157.1 similar to HYAC_ECOLI gi|1787208 (conserved in Escherichia coli K-12) NP_309158.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) NP_309159.1 involved in processing hydrogenases HyaA and HyaB NP_309160.1 similar to HYAF_ECOLI gi|1787211 (conserved in Escherichia coli K-12) NP_309161.1 similar to APPC_ECOLI gi|1787212 (conserved in Escherichia coli K-12) NP_309162.1 similar to APPB_ECOLI gi|1787213 (conserved in Escherichia coli K-12) NP_309163.1 similar to phosphoanhydride phosphorylase APPA_ECOLI gi|1787215 (conserved in Escherichia coli K-12) NP_309164.1 similar to YCCC_ECOLI gi|1787216 (conserved in Escherichia coli K-12) NP_309165.2 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk NP_309166.1 function in exopolysaccharide production; similar to YCCZ_ECOLI gi|1787218 (conserved in Escherichia coli K-12) NP_309167.1 similar to YMCA_ECOLI gi|1787219 (conserved in Escherichia coli K-12) NP_309168.1 similar to YMCB_ECOLI gi|1787220 (conserved in Escherichia coli K-12) NP_309169.1 similar to YMCC_ECOLI gi|1787221 (conserved in Escherichia coli K-12) NP_309170.1 similar to YMCD_ECOLI gi|1787222 (conserved in Escherichia coli K-12) NP_309171.1 similar to CSPH_ECOLI gi|2367112 (conserved in Escherichia coli K-12) NP_309172.1 similar to CSPG_ECOLI gi|2367114 (conserved in Escherichia coli K-12) NP_309173.1 similar to SFA_ECOLI gi|1787225 (conserved in Escherichia coli K-12) NP_309174.1 similar to YCCM_ECOLI gi|1787226 (conserved in Escherichia coli K-12) NP_309175.2 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide NP_309176.1 periplasmic sensory protein associated with the TorRS two-component regulatory system NP_309177.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes NP_309178.1 similar to TORC_ECOLI gi|1787230 (conserved in Escherichia coli K-12) NP_309179.1 similar to TORA_ECOLI gi|1787231 (conserved in Escherichia coli K-12) NP_309180.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor NP_309181.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA NP_309182.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock NP_309185.1 similar to AGP_ECOLI gi|1787237 (conserved in Escherichia coli K-12) NP_309186.1 similar to YCCJ_ECOLI gi|1787238 (conserved in Escherichia coli K-12) NP_309187.1 similar to integrase [Bacteriophage 933W] gi|4585378|gb|AAD25406.1|AF125520_1 and [Escherichia coli rac prophage] gi|6166234|sp|P76056|INTR_ECOLI NP_309188.1 similar to excisionase [Bacteriophage 933W] gi|4585379|gb|AAD25407.1|AF125520_2 NP_309189.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585380|gb|AAD25408.1|AF125520_3 NP_309190.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585381|gb|AAD25409.1|AF125520_4 NP_309191.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585382|gb|AAD25410.1|AF125520_5; similar to hypothetical protein [Bacteriophage 933W] gi|4585455|gb|AAD25483.1|AF125520_78 NP_309192.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585383|gb|AAD25411.1|AF125520_6 NP_309193.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585384|gb|AAD25412.1|AF125520_7 NP_309194.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585385|gb|AAD25413.1|AF125520_8 NP_309195.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881600|dbj|BAA84291.1 NP_309196.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585386|gb|AAD25414.1|AF125520_9, similar to hypothetical protein [Bacteriophage 933W] gi|4585455|gb|AAD25483.1|AF125520_78 NP_309197.1 similar to C4-type zinc finger proteins (TraR family) e.g. gi|4585456|gb|AAD25484.1|AF125520_79 NP_309198.1 similar to hypothetical protein [Bacteriophage 933W]; similar to orf61 [Bacteriophage lambda] gi|508993|gb|AAA96566.1 NP_309199.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881603|dbj|BAA84294.1|, similar to orf63 [Bacteriophage lambda] gi|508994|gb|AAA96567.1 NP_309200.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881604|dbj|BAA84295.1, similar to orf60a [Bacteriophage lambda] gi|508995|gb|AAA96568.1 NP_309201.1 similar to exonuclease [Bacteriophage lambda] gi|2981722|pdb|1AVQ|A NP_309202.1 similar to Bet [Bacteriophage VT2-Sa] gi|5881606|dbj|BAA84297.1 and [Bacteriophage lambda] gi|137511|sp|P03698|VBET_LAMBD NP_309203.1 host-nuclease inhibitor protein; similar to Gam protein [Bacteriophage lambda] gi|138128|sp|P03702|VGAM_LAMBD NP_309204.1 similar to kil [Bacteriophage VT2-Sa] gi|5881608|dbj|BAA84299.1 and [Bacteriophage lambda] gi|138622|sp|P03758|VKIL_LAMBD NP_309205.1 antitermination; similar to cIII [Bacteriophage lambda] gi|133366|sp|P03044|RPC3_LAMBD NP_309206.1 single strand binding protein; similar to Ea10 [Bacteriophage VT2-Sa] gi|5881610|dbj|BAA84301.1 and [Bacteriophage lambda] gi|137630|sp|P03757|VE10_LAMBD NP_309207.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881612|dbj|BAA84303.1 NP_309208.1 similar to N protein [Bacteriophage VT2-Sa] gi|5881613|dbj|BAA84304.1 and [Bacteriophage 933W] gi|4585397|gb|AAD25425.1|AF125520_20 NP_309211.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881614|dbj|BAA84305.1 NP_309212.1 similar to cI [Bacteriophage lambda] gi|133353|sp|P03034|RPC1_LAMBD NP_309213.1 probable regulatory protein, similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881616|dbj|BAA84307.1 and c2 [Bacteriophage L] gi|1469215|emb|CAA63999.1 NP_309214.1 regulatory protein; similar to CII [Bacteriophage VT2-Sa] gi|5881617|dbj|BAA84308.1 and [Enterobacteria phage HK022] gi|631957|pir||S42398 NP_309215.1 similar to hypothetical protein [Enterobacteria phage HK022] gi|632160|pir||S42399, orf48 [Bacteriophage P22] gi|871503|emb|CAA55155.1 NP_309216.1 similar to O proteins e.g. O [Enterobacteria phage HK022] gi|407289|gb|AAB60272.1 NP_309217.1 replicative DNA helicase; similar to P protein [Enterobacteria phage HK022] gi|6863143|gb|AAF30384.1|AF069308_32, replicative DNA helicase DnaB [Escherichia col NP_309218.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881620|dbj|BAA84311.1 NP_309219.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499788|emb|CAB39287.1 NP_309220.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499789|emb|CAB39288.1 NP_309221.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881622|dbj|BAA84313.1 and [Bacteriophage 933W] gi|4499790|emb|CAB39289.1 NP_309222.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881623|dbj|BAA84314.1 and NinB protein [Bacteriophage 21] NP_309223.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881624|dbj|BAA84315.1 and Gp62 [Bacteriophage HK97] gi|6901634|gb|AAF31137.1 NP_309224.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881625|dbj|BAA84316.1 and NinE protein [Bacteriophage 21] gi|4539480|emb|CAB39989.1 NP_309226.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881627|dbj|BAA84318.1 and antirepressor protein Ant [Bacteriophage P22] NP_309227.1 similar to Roi [Bacteriophage VT2-Sa] gi|5881628|dbj|BAA84319.1 and Roi proteins e.g. [Enterobacteria phage HK022] gi|1197729|gb|AAC48863.1 NP_309228.1 similar to hypothetical protein orf15 [Bacteriophage 933W] gi|4499798|emb|CAB39297.1 and NinG protein [Bacteriophage 21] gi|4539482|emb|CAB39991.1 NP_309229.1 similar to hypothetical protein orf16 [Bacteriophage 933W] gi|4499799|emb|CAB39298.1 and hypothetical proteins e.g. Nin68 [Bacteriophage lambda] gi|9626304|ref|NP_040640.1 NP_309230.1 similar to antitermination protein Q [Bacteriophage 933W] gi|4585416|gb|AAD25444.1|AF125520_39 and antitermination Q proteins e.g. [Bacteriophage H-19B] gi|2668768|gb|AAD04655.1 NP_309231.1 similar to hypothetical protein [Bacteriophage P27] gi|8346570|emb|CAB93763.1| NP_309232.1 similar to gi|1351074|sp|P09385|SLTA_BP933 NP_309233.1 similar to gi|134538|sp|P09386|SLTB_BP933 NP_309234.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 and YjhS [Shigella dysenteriae] gi|6759965|gb| NP_309235.1 OrfB protein of insertion sequence IS629; similar to gi|7443862|pir||T00240 NP_309236.1 OrfA protein of insertion sequence IS629; similar to gi|7444868|pir||T00241 NP_309237.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499806|emb|CAB39305.1 NP_309238.2 similar to hypothetical protein [Bacteriophage 933W] gi|4585420|gb|AAD25448.1|AF125520_43 NP_309239.1 similar to protein S [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1 and [Shigella dysenteriae] gi|6759967|gb|AAF28125.1|AF153317_21 NP_309240.1 similar to endolysin [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45 and endolysins e.g. [Bacteriophage H-19B] gi|4335686|gb|AAD17382.1 NP_309241.1 similar to antirepressor protein [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46 and antirepressor protein Ant [Bacteriophage P22] gi|131843|sp|P03037|RANT_BPP22 NP_309242.1 similar to endopeptidase [Bacteriophage 933W] gi|4585424|gb|AAD25452.1|AF125520_47 and Rz [Bacteriophage lambda] gi|119368|sp|P00726|ENPP_LAMBD NP_309244.1 similar to [Bacteriophage 933W] gi|4585426|gb|AAD25454.1|AF125520_49 and Bor protein precursor [Bacteriophage lambda] gi|137520|sp|P26814|VBOR_LAMBD NP_309245.2 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881640|dbj|BAA84331.1 NP_309246.1 similar to small subunit terminase [Bacteriophage 933W] gi|4585427|gb|AAD25455.1|AF125520_50 NP_309247.1 similar to terminase large subunit [Bacteriophage 933W] gi|4585428|gb|AAD25456.1|AF125520_51 NP_309248.1 similar to portal protein [Bacteriophage 933W] gi|4585429|gb|AAD25457.1|AF125520_52 NP_309249.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585430|gb|AAD25458.1|AF125520_53 NP_309250.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585431|gb|AAD25459.1|AF125520_54 NP_309251.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585432|gb|AAD25460.1|AF125520_55 NP_309252.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585433|gb|AAD25461.1|AF125520_56 NP_309253.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585434|gb|AAD25462.1|AF125520_57 NP_309254.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585435|gb|AAD25463.1|AF125520_58 NP_309255.1 similar to tail fiber protein [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_309256.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_309257.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585438|gb|AAD25466.1|AF125520_61 NP_309259.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585439|gb|AAD25467.1|AF125520_62, [Bacteriophage P-EibD] gi|7523538|gb|AAF63043.1|AF151675_5 NP_309260.1 similar to tail tip fiber protein gp21 [phage N15] gi|7444604|pir||T13107, [Bacteriophage 933W] gi|4585440|gb|AAD25468.1|AF125520_63; probable tail tip fiber protein NP_309261.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585441|gb|AAD25469.1|AF125520_64 NP_309262.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585442|gb|AAD25470.1|AF125520_65 NP_309263.1 similar to tail gene products e.g. [Yersinia pseudotuberculosis] gi|5902750|sp|Q56957|AIL_YERPS, outer membrane protein Lom precursor gi|138693|sp|P03701|VLOM_LAMBD, virulence protein pagC precursor [Salmonella typhimurium] gi|129558|sp|P23988|PAGC_SALTY, Lom precursor [Bacteriophage 933W] gi|4585443|gb|AAD25471.1|AF125520_66, outer membrane protein rck [Salmonella typhimurium] gi|282013|pir||A43309 NP_309264.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585444|gb|AAD25472.1|AF125520_67 NP_309265.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585445|gb|AAD25473.1|AF125520_68 NP_309266.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585446|gb|AAD25474.1|AF125520_69 NP_309267.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585447|gb|AAD25475.1|AF125520_70 NP_309268.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585448|gb|AAD25476.1|AF125520_71 NP_309269.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585449|gb|AAD25477.1|AF125520_72 NP_309270.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585450|gb|AAD25478.1|AF125520_73 NP_309271.1 similar to hypothetical protein [Bacteriophage 933W] gi|9632540|ref|NP_049534.1, ygiW protein precursor [Escherichia coli] gi|1723887|sp|P52083|YGIW_ECOLI NP_309272.1 similar to MokW [Bacteriophage 933W] gi|4585453|gb|AAD25481.1|AF125520_76, GelF [Escherichia coli] gi|1786200|gb|AAC73129.1 NP_309273.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585454|gb|AAD25482.1|AF125520_77 NP_309274.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881668|dbj|BAA84359.1, [Bacteriophage 933W] gi|4585455|gb|AAD25483.1|AF125520_78 NP_309275.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881669|dbj|BAA84360.1, [Bacteriophage 933W] gi|7649907|dbj|BAA94185.1 NP_309276.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881670|dbj|BAA84361.1 NP_309277.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881671|dbj|BAA84362.1, C4-type zinc finger proteins (TraR family) e.g. orf39 [Pseudomonas aeruginosa phage phi CTX] gi|4063813|dbj|BAA36267 NP_309278.1 similar to phage anti-repressor proteins e.g. [Neisseria meningitidis] gi|7379969|emb|CAB84545.1, [Bacteriophage VT2-Sa] gi|5881672|dbj|BAA84363.1, HI1422 [Haemophilus influenzae Rd] gi|1175795|sp|P44193|YE22_HAEIN NP_309279.2 similar to YCDG_ECOLI gi|1787241 (conserved in Escherichia coli K-12) NP_309280.2 similar to B1007_ECOLI gi|1787242 (conserved in Escherichia coli K-12) NP_309281.1 similar to B1008_ECOLI gi|1787243 (conserved in Escherichia coli K-12) NP_309282.1 similar to B1009_ECOLI gi|1787244 (conserved in Escherichia coli K-12) NP_309283.1 similar to B1010_ECOLI gi|1787245 (conserved in Escherichia coli K-12) NP_309284.2 similar to B1011_ECOLI gi|1787246 (conserved in Escherichia coli K-12) NP_309285.2 similar to B1012_ECOLI gi|1787247 (conserved in Escherichia coli K-12) NP_309286.1 similar to YCDC_ECOLI gi|1787249 (conserved in Escherichia coli K-12) NP_309287.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein NP_309288.1 similar to PUTP_ECOLI gi|1787251 (conserved in Escherichia coli K-12) NP_309290.1 similar to B1016_ECOLI gi|1787252, B1017_ECOLI gi|1787253 NP_309291.1 similar to YCDO_ECOLI gi|1787254 (conserved in Escherichia coli K-12) NP_309292.1 similar to YCDB_ECOLI gi|1787255 (conserved in Escherichia coli K-12) NP_309293.1 ATP-binding pho regulon component; similar to PHOH_ECOLI gi|1787257 (conserved in Escherichia coli K-12) NP_309294.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export NP_309295.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein NP_309296.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export NP_309297.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia NP_309298.1 similar to YCDT_ECOLI gi|1787262 (conserved in Escherichia coli K-12) NP_309299.1 may confer resistance to phages N4 and lambda; similar to Rtn membrane associated protein [Escherichia coli]gi|2498867|sp|P76446|RTN_ECOLI NP_309300.1 similar to FidL -Salmonella typhimurium gi|4324611|gb|AAD16955.1 NP_309301.1 similar to transcriptional activators e.g. MarT [Salmonella typhimurium] gi|4324612|gb|AAD16956.1 NP_309302.2 similar to oxidoreductases e.g. [Escherichia coli] gi|2492762|sp|P76633|YGCW_ECOLI NP_309303.1 similar to hypothetical proteins e.g. ORF60 [Yersinia pestis] gi|7467334|pir||T17432, chaperone proteins e.g. EcpD [Escherichia coli] gi|2506408|sp|P33128|ECPD_ECOLI NP_309304.1 similar to hypothetical proteins e.g. ORF59 [Yersinia pestis] gi|4106627|emb|CAA21382.1 NP_309305.1 similar to hypothetical protein ORF 58 [Yersinia pestis] gi|4106626|emb|CAA21381.1, outer membrane usher proteins e.g. FimD [Salmonella typhimurium gi|585135|sp|P3792 NP_309306.2 similar to hypothetical protein ORF57 [Yersinia pestis] gi|4106625|emb|CAA21380.1, chaperone proteins e.g. EcpD [Escherichia coli] gi|2506408|sp|P33128|ECPD_ECOLI NP_309307.1 similar to hypothetical protein ORF56 [Yersinia pestis] gi|4106624|emb|CAA21379.1, major pilin proteins e.g. SfaA [Escherichia coli] gi|4105989|gb|AAD02646.1 NP_309309.1 similar to hemagglutinin/hemolysin-related proteins [Neisseria meningitidis] e.g. gi|7225719|gb|AAF40927.1 NP_309310.1 similar to hemolysin activator-related proteins e.g. [Pectobacterium chrysanthemi] gi|1772622|gb|AAC31980.1 NP_309311.1 similar to holo-[acyl-carrier protein] synthases e.g. [Campylobacter jejuni] gi|6968838|emb|CAB73833.1 NP_309312.1 similar to 3-oxoacyl-(acyl carrier protein) reductases e.g. [Moritella marina] gi|7227179|gb|AAF42251.1 NP_309313.1 similar to (3R)-hydroxymyristol-(acyl carrier protein) dehydratases e.g. gi|7190847|gb|AAF39621.1 NP_309314.2 similar to acyl carrier proteins e.g. AcpC [Streptococcus agalactiae] gi|4886773|gb|AAD32036.1|AF093787_4 NP_309315.1 similar to aminpometyl transferases e.g. gi|7450600|pir||C75088 NP_309316.1 similar to 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) [Bacillus subtilis] gi|7433750|pir||G69842 NP_309317.1 similar to polyketide synthases e.g. [Streptomyces sp. strain MA6548] gi|7481905|pir||T17428 NP_309319.1 similar to ABC transporters (ATP binding proteins) e.g. [Thermotoga maritima] gi|7445988|pir||H72342 NP_309321.1 similar to hypothetical proteins e.g. BBJ27 [Lyme disease spirochete plasmid J/lp38] gi|7463605|pir||D70248 NP_309324.1 similar to B1028_ECOLI gi|1787266 (conserved in Escherichia coli K-12) NP_309325.1 similar to YCDU_ECOLI gi|1787267 (conserved in Escherichia coli K-12) NP_309326.1 similar to integrases e.g. [Vibrio cholerae] gi|498253|gb|AAC44230.1| NP_309327.1 similar to hemagglutinin main component [Clostridium botulinum phage (type C)] gi|1346254|sp|P46084|HA33_CLOBO NP_309328.1 similar to InsB proteins e.g. [Shigella dysenteriae Iso-IS1] gi|6759959|gb|AAF28117.1|AF153317_13 NP_309329.1 similar to prophage cp4-57 regulatory protein AlpA [Escherichia coli (strain K-12)] gi|461502|sp|P33997|ALPA_ECOLI NP_309330.1 similar to hypothetical protein b2625 (YfjI) [Escherichia coli K-12] gi|1723621|sp|P52124|YFJI_ECOLI NP_309331.1 similar to hypothetical protein Cj1244 [Campylobacter jejuni] gi|6968677|emb|CAB73498.1 NP_309332.1 similar to hypothetical protein A153R [Chlorella virus PBCV-1] gi|7461298|pir||T17644, DNA repair protein rad25 PAB0128 [Pyrococcus abyssi (strain Orsay)] gi|7514780|pir||A75209 NP_309334.1 similar to L0015 [Escherichia coli] gi|3414883|gb|AAC31494.1 and hypothetical protein [Escherichia coli] gi|3288156|emb|CAA11509.1 NP_309335.1 similar to L0014 [Escherichia coli] gi|3288157|emb|CAA11510.1 and hypothetical proteins e.g. orf50 [Escherichia coli] gi|6009426|dbj|BAA84885.1 NP_309336.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli] gi|3414881|gb|AAC31492.1| NP_309338.1 similar to transposases e.g. Hp1 [Escherichia coli] gi|3661482|gb|AAC61713.1 and InsB [Shigella dysenteriae] gi|5532467|gb|AAD44751.1|AF141323_22 NP_309339.1 similar to lipoprotein traT precursors e.g. gi|418135|sp|P32885|TRT1_ECOLI NP_309343.1 similar to diacylglycerol kinases e.g. gi|125321|sp|P00556|KDGL_ECOLI NP_309344.1 similar to hypothetical proteins e.g. yjdB in basS-adiY intergenic region [Escherichia coli] gi|731986|sp|P30845|YJDB_ECOLI NP_309348.1 similar to UreD [Klebsiella aerogenes] gi|731078|sp|Q09063|URED_KLEAE NP_309349.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter NP_309350.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active NP_309351.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits NP_309352.1 involved in the assembly of the urease metallocenter; possible nickel donor NP_309353.1 urease accessory protein; similar to urease accessory proteins UreF e.g. [Klebsiella aerogenes] gi|137097|sp|P18318|UREF_KLEAE NP_309354.1 urease accessory protein; similar to UreG urease accessory proteins e.g. [Klebsiella aerogenes] gi|137099|sp|P18319|UREG_KLEAE NP_309355.1 similar to TnpJ [Shigella flexneri] gi|5532468|gb|AAD44752.1|AF141323_23 NP_309357.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_309363.1 similar to hypothetical protein [Pseudomonas putida] gi|2995633|gb|AAC98738.1 and L0015 [Escherichia coli] gi|3414883|gb|AAC31494.1 NP_309364.1 similar to hypothetical protein orf29 [Escherichia coli] gi|6009405|dbj|BAA84864.1 and L0013 [Escherichia coli] gi|3414881|gb|AAC31492.1 NP_309365.1 similar to hypothetical protein orf50 [Escherichia coli] gi|6009426|dbj|BAA84885.1 and L0014 [Escherichia coli] gi|3288157|emb|CAA11510.1 NP_309366.1 similar to hypothetical protein L0015 [Escherichia coli] gi|3414883|gb|AAC31494.1 NP_309367.1 similar to hypothetical protein 57.8 kD protein [Pseudomonas putida] gi|2496740|sp|P55630|Y4QI_RHISN NP_309370.1 immunity to R478 phage/colicin/tellurite resistance cluster; similar to TerW [Plasmid R478] gi|1354147|gb|AAC44736.1 NP_309372.1 similar to hypothetical protein [Deinococcus radiodurans] gi|7472167|pir||B75302 NP_309373.1 similar to hypothetical protein [Streptomyces coelicolor A3(2)] gi|7472048|pir||A75302 NP_309374.1 similar to hypothetical protein [Streptomyces coelicolor A3(2)] gi|8246803|emb|CAB92838.1 NP_309375.1 similar to hypothetical protein [Serratia marcescens] gi|1695868|gb|AAB37122.1 NP_309376.1 similar to hypothetical protein [Serratia marcescens] gi|1695869|gb|AAB37123.1, [Deinococcus radiodurans (strain R1)] gi|7471591|pir||F75301 NP_309377.1 similar to hypothetical protein [Serratia marcescens] gi|1695870|gb|AAB37124.1, [Serratia marcescens] gi|1695871|gb|AAB37125.1, [Deinococcus radiodurans] gi|7471522|pir||E7530 NP_309378.1 tellurium resistance protein; similar to TerZ protein [Serratia marcescens] gi|6094454|sp|Q52353 NP_309379.1 tellurium resistance protein; similar to TerA protein [Serratia marcescens] gi|5702379|gb|AAD47285.1|AF168355_3 NP_309380.1 tellurium resistance protein; similar to TerB protein [Serratia marcescens] gi|950680|gb|AAA86848.1 NP_309381.1 tellurium resistance protein; similar to TerC protein [Serratia marcescens] gi|6226214|sp|Q52356|TERC_SERMA NP_309382.1 tellurium resistance protein; similar to terD proteins e.g. [Serratia marcescens] gi|6094448|sp|Q52357|TERD_SERMA NP_309383.1 tellurium resistance protein; similar to gi|7108482|gb|AAF36434.1|AF126104_3 TLRB_ECOLI, TerE [Serratia marcescens] gi|6094449|sp|Q52358|TERE_SERMA NP_309387.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor NP_309389.1 similar to ShiA [Shigella flexneri] gi|5532447|gb|AAD44731.1|AF141323_2 NP_309397.1 similar to glucosyl-transferases [Salmonella typhi] gi|7467230|pir||T30292 NP_309399.1 similar to transposases e.g. [Shigella boydii] gi|2197010|gb|AAB61273.1 NP_309400.1 repressor; similar to InsA proteins e.g. [insertion sequence IS1F] gi|124915|sp|P19767|ISA2_ECOLI NP_309404.1 similar to sensor-regulator protein HutT [Rhodobacter capsulatus] gi|1075537|pir||A49938 NP_309407.1 OrfB; similar to transposase [insertion sequenceIS629] gi|7443863|pir||T00315 NP_309408.1 OrfA; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_309409.1 similar to hemolysin activation protein HecB [Neisseria meningitidis MC58] gi|7227016|gb|AAF42103.1 NP_309413.1 similar to hypothetical protein YbdN [Escherichia coli] gi|3024984|sp|P77216|YBDN_ECOLI NP_309414.1 similar to hypothetical protein YbdM [Escherichia coli] gi|3024983|sp|P77174|YBDM_ECOLI NP_309415.1 similar to PerC (BfpW) [Escherichia coli] gi|1172431|sp|P43475|PERC_ECOLI NP_309416.1 similar to exopolyphosphatase [Pseudomonas aeruginosa] gi|4200042|dbj|BAA74460.1 NP_309419.1 similar to hypothetical protein [Pseudomonas syringae] gi|1196744|gb|AAA88435 NP_309420.1 similar to hypothetical protein orf29 [Escherichia coli] gi|6009405|dbj|BAA84864.1, L0013 [Escherichia coli] gi|3414881|gb|AAC31492.1 NP_309422.1 similar to hypothetical proteins e.g. yfjP protein [Escherichia coli] gi|7449539|pir||B65042, YeeP [Escherichia coli] gi|2495624|sp|P76359|YEEP_ECOLI NP_309423.1 similar to adhesin AIDA-I precursor [Escherichia coli plasmid pIB6] gi|543788|sp|Q03155|AIDA_ECOLI, glycoprotein [Escherichia coli strain H10407] gi|5305639|gb|AAD41751.1, outer membrane fluffing protein [Escherichia coli] gi|7466262|pir||G64964; adhesin-like protein NP_309424.1 similar to hypothetical protein YjDA [Escherichia coli] gi|731985|sp|P16694|YJDA_ECOLI NP_309425.1 similar to hypothetical protein YjcZ [Escherichia coli] gi|731984|sp|P39267|YJCZ_ECOLI NP_309428.1 similar to hypothetical protein YfjQ [Escherichia coli] gi|1723629|sp|P52132|YFJQ_ECOLI, YafZ [Escherichia coli] gi|2495487|sp|P77206|YAFZ_ECOLI NP_309429.1 similar to hypothetical protein YafK [Escherichia coli] gi|2495486|sp|P75676|YAFX_ECOLI, YfjX [Escherichia coli] gi|1723636|sp|P52139|YFJX_ECOLI NP_309430.1 probable DNA repair protein (RadC family), similar to RadC family protein YkfG [Escherichia coli] gi|3025218|sp|Q47685|YKFG_ECOLI, YeeS [Escherichia coli] gi|3025155|sp|P76362|YEES_ECOLI NP_309431.1 similar to hypothetical protein YeeT [Escherichia coli] gi|3025156|sp|P76363|YEET_ECOLI NP_309432.1 similar to hypothetical protein YeeU [Escherichia coli] gi|3025157|sp|P76364|YEEU_ECOLI, YfjZ [Escherichia coli] gi|1723638|sp|P52141|YFJZ_ECOLI NP_309433.1 similar to hypothetical protein L0007 [Escherichia coli] gi|3414875|gb|AAC31486.1, YeeV [Escherichia coli] gi|3025158|sp|P76365|YEEV_ECOLI, YkfI [Escherichia coli] gi|3025213|s NP_309434.1 similar to hypothetical protein L0008 [Escherichia coli] gi|3414876|gb|AAC31487.1, YeeW [Escherichia coli] gi|3025160|sp|P76366|YEEW_ECOLI NP_309435.1 similar to hypothetical protein L0009 [Escherichia coli] gi|3414877|gb|AAC31488.1 NP_309436.1 similar to hypothetical protein L0010 [Escherichia coli] gi|3414878|gb|AAC31489.1, ydiA [Plasmid ColIb-P9] gi|4512489|dbj|BAA75138.1, L0012 [Escherichia coli] gi|3414880|gb|A NP_309437.1 similar to YCDW_ECOLI gi|1787270 (conserved in Escherichia coli K-12) NP_309438.1 similar to YCDX_ECOLI gi|1787271 (conserved in Escherichia coli K-12) NP_309439.1 similar to YCDY_ECOLI gi|1787272 (conserved in Escherichia coli K-12) NP_309440.2 similar to YCDZ_ECOLI gi|1787273 (conserved in Escherichia coli K-12) NP_309441.1 curli production assembly/transport component; similar to CSGG_ECOLI gi|1787274 (conserved in Escherichia coli K-12) NP_309442.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex NP_309443.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex NP_309444.1 activates the csgBA and csgDEFG operons involved in biofilm formation NP_309446.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface NP_309447.1 similar to CSGA_ECOLI gi|1787279 (conserved in Escherichia coli K-12) NP_309448.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers NP_309449.1 similar to B1044_ECOLI gi|1787281 (conserved in Escherichia coli K-12) NP_309450.1 similar to B1045_ECOLI gi|1787283 (conserved in Escherichia coli K-12) NP_309451.1 similar to YMDC_ECOLI gi|1787284 (conserved in Escherichia coli K-12) NP_309452.1 required for the transfer of succinyl residues to the glucan backbone NP_309453.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan NP_309454.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space NP_309455.1 similar to YCEK_ECOLI gi|1787288 (conserved in Escherichia coli K-12) NP_309456.2 acidic protein; similar to MSYB_ECOLI gi|1787289 (conserved in Escherichia coli K-12) NP_309459.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA NP_309460.1 similar to YCEA_ECOLI gi|1787294 (conserved in Escherichia coli K-12) NP_309461.1 similar to YCEI_ECOLI gi|1787295 (conserved in Escherichia coli K-12) NP_309462.1 similar to B1057_ECOLI gi|1787296 (conserved in Escherichia coli K-12) NP_309463.1 similar to YCEO_ECOLI gi|1787297 (conserved in Escherichia coli K-12) NP_309464.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids NP_309465.3 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing NP_309466.1 damage-inducible protein; similar to DINI_ECOLI gi|1787300 (conserved in Escherichia coli K-12) NP_309467.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis NP_309468.1 similar to YCEB_ECOLI gi|1787302 (conserved in Escherichia coli K-12) NP_309469.1 cofactor involved in the reduction of disulfides NP_309470.2 Confers resistance to norfloxacin and enoxacin NP_309471.1 similar to RIMJ_ECOLI gi|1787305 (conserved in Escherichia coli K-12) NP_309472.1 similar to YCEH_ECOLI gi|1787306 (conserved in Escherichia coli K-12) NP_309473.1 similar to MVIM_ECOLI gi|1787307 (conserved in Escherichia coli K-12) NP_309474.1 similar to MVIN_ECOLI gi|1787309 (conserved in Escherichia coli K-12) NP_309475.1 similar to FLGN_ECOLI gi|1787310 (conserved in Escherichia coli K-12) NP_309476.1 regulates the flagellar specific sigma28 transcription factor NP_309477.1 required for the assembly of the flagellar basal body P-ring NP_309478.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella NP_309479.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod NP_309480.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production NP_309481.1 the hook connects flagellar basal body to the flagellar filament NP_309482.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod NP_309483.1 makes up the distal portion of the flagellar basal body rod NP_309484.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod NP_309485.2 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum NP_309486.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space NP_309487.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook NP_309488.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes NP_309489.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase NP_309490.1 similar to B1085_ECOLI gi|1787326 (conserved in Escherichia coli K-12) NP_309491.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA NP_309492.2 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_309493.1 similar to YCED_ECOLI gi|1787329 (conserved in Escherichia coli K-12) NP_309494.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_309495.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_309496.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_309497.1 similar to FABD_ECOLI gi|1787334 (conserved in Escherichia coli K-12) NP_309498.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_309499.1 carries the fatty acid chain in fatty acid biosynthesis NP_309500.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_309501.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate NP_309502.1 similar to YCEG_ECOLI gi|1787339 (conserved in Escherichia coli K-12) NP_309503.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_309504.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_309505.1 similar to YCFH_ECOLI gi|1787342 (conserved in Escherichia coli K-12) NP_309506.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_309507.1 similar to FHUE_ECOLI gi|1787344 (conserved in Escherichia coli K-12) NP_309508.2 similar to YCFF_ECOLI gi|1787346 (conserved in Escherichia coli K-12) NP_309509.1 similar to YCFL_ECOLI gi|1787347 (conserved in Escherichia coli K-12) NP_309510.1 similar to YCFM_ECOLI gi|1787348 (conserved in Escherichia coli K-12) NP_309511.1 catalyzes the phosphorylation of thiamine to thiamine phosphate NP_309512.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides NP_309513.2 similar to YCFP_ECOLI gi|1787351 (conserved in Escherichia coli K-12) NP_309514.1 similar to NDH_ECOLI gi|1787352 (conserved in Escherichia coli K-12) NP_309515.1 similar to YCFJ_ECOLI gi|1787353 (conserved in Escherichia coli K-12) NP_309516.2 similar to YCFQ_ECOLI gi|1787354 (conserved in Escherichia coli K-12) NP_309517.1 similar to YCFR_ECOLI gi|1787355 (conserved in Escherichia coli K-12) NP_309518.1 similar to YCFS_ECOLI gi|1787356 (conserved in Escherichia coli K-12) NP_309519.1 similar to MFD_ECOLI gi|1787357 (conserved in Escherichia coli K-12) NP_309520.1 similar to YCFT_ECOLI gi|1787359 (conserved in Escherichia coli K-12) NP_309521.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane NP_309522.2 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone NP_309523.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane NP_309524.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine NP_309525.1 Modulates the activities of several enzymes which are inactive in their acetylated form NP_309526.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate NP_309527.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component NP_309528.1 similar to integrase [Escherichia coli prophage e14] gi|3024035|sp|P75969|INTE_ECOLI NP_309529.1 similar to excisionase [bacteripohage P21] gi|139674|sp|P27079|VXIS_BPP21 NP_309532.1 similar to hypothetical protein YdfA [Escherichia coli] gi|140584|sp|P29008|YDFA_ECOLI NP_309533.1 similar to repressor [Escherichia col Rac prophage] gi|3025101|sp|P76062|RACR_ECOLI NP_309534.1 similar to YdaS [Escherichia coli] gi|3025102|sp|P76063|YDAS_ECOLI NP_309535.1 similar to YdaT [Escherichia coli] gi|3183265|sp|P76165|YDFX_ECOLI NP_309536.1 similar to replication termination protein DnaT (prepriming protein I) [Escherichia coli] gi|1361001|pir||S56589 NP_309537.1 similar to replication protein 14 [Bacteriophage phi-80] gi|137937|sp|P14814|VG14_BPPH8 NP_309538.1 similar to YdaW [Escherichia coli] gi|3025105|sp|P76066|YDAW_ECOLI NP_309540.1 similar to Gp57 [Bacteriophage N15] gi|7459176|pir||T13144 NP_309541.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881670|dbj|BAA84361.1| NP_309543.1 similar to hypothetical protein Ea22 [Bacteriophage lambda] gi|137663|sp|P03756|VE22_LAMBD NP_309545.1 similar to hypothetical protein b2363 [Escherichia coli] H65009, hypothetical protein Bacteriophage 933W AAD25410 NP_309547.1 similar to Hok/Gef family e.g. MokW [Bacteriophage 933W] gi|4585453|gb|AAD25481.1|AF125520_76 NP_309548.1 similar to QD1 [Bacteriophage N15] gi|2564084|gb|AAB81659.1 NP_309549.1 similar to b1560 [Escherichia coli] gi|1742555|dbj|BAA15259.1, hypothetical protein A [phage P1] gi|732234|sp|Q06262|YORA_BPP1 NP_309550.1 similar to Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1, crossover junction endodeoxyribonucleases Rus [Escherichia coli cryptic lambdoid prophage DLP12 NP_309551.1 similar to antitermination protein protein Q [Escherichia coli] gi|1742554|dbj|BAA15258.1 NP_309554.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881634|dbj|BAA84325.1 NP_309555.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499806|emb|CAB39305.1 NP_309556.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881635|dbj|BAA84326.1 NP_309557.1 similar to holin S protein [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1 NP_309558.1 similar to YdfR [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_309559.1 similar to R protein [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45 NP_309560.1 similar to antirepressor protein [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46, antirepressor protein Ant [Bacteriophage P22] gi|131843|sp|P03037|RANT_BPP22 NP_309561.1 host cell lysis; similar to endopeptidases e.g. Rz [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1 NP_309564.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881640|dbj|BAA84331.1 NP_309566.1 similar to hypothetical proteins [Escherichia coli] gi|1778472|gb|AAB40755.1 NP_309567.1 similar to DNAse [Bacteriophage phi-31] gi|1107475|emb|CAA62587.1 NP_309568.1 similar to terminase small subunit [Bacillus subtilis PBSX phage] gi|1722886|sp|P39785|XTMA_BACSU NP_309569.1 similar to hypothetical protein phage D3 terminase-like protein [Haemophilus influenzae] gi|6739656|gb|AAF27357.1|AF198256_11 NP_309570.1 similar to prohead protease Gp4 [Bacteriophage HK97] gi|1722780|sp|P49860|VP4_BPHK7 NP_309571.1 similar to portal protein [Bacteriophage HK022] gi|6863114|gb|AAF30355.1|AF069308_3 NP_309573.1 similar to head-tail adaptor [Bacteriophage HK97] gi|6901597|gb|AAF31100.1 NP_309574.1 similar to hypothetical phage protein Gp10 [Bacteriophage HK97] gi|6901598|gb|AAF31101.1 NP_309575.1 similar to Gp11 [Bacteriophage HK97] gi|6901599|gb|AAF31102.1 NP_309576.1 similar to major tail subunit [Bacteriophage HK97] gi|6901588|gb|AAF31091.1|AF069529_4 NP_309577.1 similar to tail assembly chaperone Gp14 [Bacteriophage HK97] gi|6901600|gb|AAF31103.1 NP_309578.1 similar to Gp14 [Bacteriophage HK97] gi|6901601|gb|AAF31104.1; may be produced by translational frameshift NP_309581.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_309582.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_309583.1 similar to regulatory protein Mnt[Bacteriophage P22] gi|133138|sp|P03049|RMNT_BPP22 NP_309584.1 similar to antirepressor protein Ant [Bacteriophage P22] gi|131843|sp|P03037|RANT_BPP22 NP_309585.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_309586.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_309587.1 similar to secreted effector protein SopA [Salmonella dublin] gi|5669806|gb|AAD46479.1|AF121227_1 NP_309588.1 similar to cytotoxic necrotizing factor type 2 [Escherichia coli] gi|1073353|pir||A55260 NP_309591.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats NP_309592.1 OrfA; similar to hypothetical protein [insertion sequence IS2] gi|140806|sp|P19776|YI21_ECOLI NP_309595.1 similar to Yop effector YopM [Yersinia enterocolitica] gi|4324334|gb|AAD16811.1 NP_309597.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component NP_309598.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase NP_309599.1 catalyzes the release of the N-terminal amino acid from a tripeptide NP_309600.2 similar to YCFD_ECOLI gi|1787373 (conserved in Escherichia coli K-12) NP_309601.1 similar to integrases e.g. [Shigella dysenteriae] gi|6759954|gb|AAF28112.1|AF153317_4 NP_309604.1 probable cell division repressor; similar to cell division repressor Icd [enterobacteria phage P1] gi|4261623|gb|AAD13923.1|S61175_1 NP_309614.1 similar to single stranded DNA-binding proteins e.g. [Thermotoga maritima] gi|7439946|pir||H72354 NP_309615.1 similar to PerC (BfpW) transcriptional activator of eaeA/bfpA [Escherichia coli] gi|1172431|sp|P43475|PERC_ECOLI NP_309617.1 similar to major head proteins e.g. phage phi-C31 gp36-like protein [Haemophilus influenzae] gi|6739663|gb|AAF27364.1|AF198256_18 (AF198256) NP_309618.2 similar to prohead proteases e.g. phage phi-C31 gp35-like protein [Haemophilus influenzae] gi|6739662|gb|AAF27363.1|AF198256_17 NP_309619.1 similar to head portal proteins e.g. phage phi-105 ORF25-like protein [Haemophilus influenzae]gi|6739661|gb|AAF27362.1|AF198256_ 16 NP_309620.1 similar to head-tail adaptors e.g. [Bacteriophage HK97] gi|6901597|gb|AAF31100.1 NP_309621.1 similar to hypothetical protein [Haemophilus influenzae] gi|6739659|gb|AAF27360.1|AF198256_14, hypothetical protein 30 [Bacillus phage phi-105] gi|7459182|pir||T13519 NP_309622.1 similar to hypothetical protein [Haemophilus influenzae] gi|6739658|gb|AAF27359.1|AF198256_13 NP_309624.1 similar to hypothetical protein of genetic island 1 [Haemophilus influenzae] gi|6739657|gb|AAF27358.1|AF198256_12 NP_309625.1 similar to terminase large subunits e.g.[Haemophilus influenzae] gi|6739656|gb|AAF27357.1|AF198256_11 NP_309628.1 sensor protein; similar to PHOQ_ECOLI gi|1787374 (conserved in Escherichia coli K-12) NP_309629.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress NP_309630.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide NP_309631.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis NP_309632.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_309633.1 similar to B1134_ECOLI gi|1787379 (conserved in Escherichia coli K-12) NP_309634.2 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA NP_309635.1 Converts isocitrate to alpha ketoglutarate NP_309636.1 similar to integrase [Bacteriophage P21] gi|138558|sp|P27077|VINT_BPP21 NP_309637.1 similar to excisionase [Bacteriophage P21] gi|139674|sp|P27079|VXIS_BPP21 NP_309638.1 similar to replication protein GpO [Bacteriophage lambda] gi|215150|gb|AAA96584.1 NP_309639.1 similar to replication protein GpP [Bacteriophage lambda] gi|4499785|emb|CAB39284.1 NP_309640.1 similar to Ren protein [Bacteriophage lambda] gi|139473|sp|P03761|VREN_LAMBD NP_309641.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation NP_309642.1 similar to hypothetical protein YbcK [Escherichia coli] gi|2495549|sp|P77698|YBCK_ECOLI, integrase [Bacteriophage A118] gi|1196324|gb|AAB51416.1 NP_309643.1 DLP12 prophage NP_309644.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins NP_309645.1 similar to YbcO [Escherichia coli cryptic prophage DLP12] gi|2495553|sp|Q47271|YBCO_ECOLI, Gp66 [Bacteriophage HK97] gi|6901638|gb|AAF31141.1 NP_309646.1 DLP12 prophage; Holliday junction resolvase NP_309647.1 similar to antitermination proteins e.g. Q [Bacteriophage 82] gi|132277|sp|P13870|REGQ_BP82 NP_309648.1 similar to holin [Bacteriophage PS3] gi|3676074|emb|CAA09700.1| NP_309649.1 lyzozyme; similar to endolysins e.g. [Bacteriophage HK97] gi|6901642|gb|AAF31145.1 NP_309650.1 host cell lysis; similar to endopeptidases e.g. [Bacteriophage lambda] gi|119368|sp|P00726|ENPP_LAMBD NP_309651.1 similar to Rs1 precursors e.g. [Bacteriophage lambda] gi|540738|pir||JN0750 NP_309652.1 similar to Bor protein precursor [Bacteriophage lambda] gi|137520|sp|P26814|VBOR_LAMBD NP_309653.1 similar to hypothetical protein YbcV [Escherichia coli] gi|2495556|sp|P77598|YBCV_ECOLI NP_309654.1 similar to YbcW [Escherichia coli] gi|2495557|sp|P75720|YBCW_ECOLI NP_309655.1 similar to hypothetical protein Escherichia coli AAB40755 NP_309656.1 similar to terminase small subunits e.g. Nu1 [Bacteriophage lambda] gi|139026|sp|P03707|TERS_LAMBD NP_309657.1 similar to terminase large subunits e.g. protein A [Bacteriophage lambda] gi|137616|sp|P03708|TERL_LAMBD NP_309658.1 similar to head-to-tail joining proteins e.g. GpW [Bacteriophage lambda] gi|138415|sp|P03727|VHTJ_LAMBD NP_309659.1 similar to portal proteins e.g. GpB [Bacteriophage lambda] gi|138762|sp|P03710|VMCB_LAMBD NP_309660.1 similar to minor capsid protein e.g. proteins C [Bacteriophage lambda] gi|137565|sp|P03711|VCAC_LAMBD NP_309661.1 similar to major capsid proteins e.g. GpD [Bacteriophage lambda] gi|137566|sp|P03712|VCAD_LAMBD NP_309662.1 similar to major capsid proteins e.g. GpE [Bacteriophage lambda] gi|116752|sp|P03713|HEAD_LAMBD NP_309663.1 similar to DNA packaging proteins e.g. GpFI [Bacteriophage lambda] gi|139324|sp|P03709|VPF1_LAMBD NP_309664.1 similar to minor capsid proteins e.g. GpFII [Bacteriophage lambda] gi|137575|sp|P03714|VCF2_LAMBD NP_309665.1 similar to minor tail proteins e.g. GpZ [Bacteriophage lambda] gi|138849|sp|P03731|VMTZ_LAMBD NP_309666.1 similar to minor tail proteins e.g. GpU [Bacteriophage lambda] gi|138847|sp|P03732|VMTU_LAMBD NP_309667.1 similar to major tail proteins e.g. GpV of [Bacteriophage lambda] gi|138848|sp|P03733|VMTV_LAMBD NP_309668.1 similar to minor tail proteins e.g. GpG [Bacteriophage lambda] gi|138842|sp|P03734|VMTG_LAMBD NP_309669.1 similar to minor tail proteins e.g. GpT [Bacteriophage lambda] gi|138846|sp|P03735|VMTT_LAMBD; may be produced by translational frameshift NP_309670.1 similar to tail length tape measure protein precursors e.g. GpH [Bacteriophage lambda] gi|138843|sp|P03736|VMTH_LAMBD NP_309671.1 similar to minor tail proteins e.g. GpM of [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_309672.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_309673.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_309674.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_309675.1 similar to host specificity proteins e.g. GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_309676.1 similar to membrane protein Lom precursors e.g. [prophage P-EibA gi|7532789|gb|AAF63231.1|AF151091_2, [Bacteriophage lambda] gi|138693|sp|P03701|VLOM_LAMBD NP_309677.1 similar to probable tail fiber proteins e.g. Gp37 [Escherichia coli] gi|7466858|pir||G64887 NP_309678.1 similar to tail fiber assembly proteins e.g. Orf194 [Bacteriophage lambda] gi|139990|sp|P03740|Y194_LAMBD NP_309679.1 similar to hypothetical proteins e.g. catalase [Salmonella typhimurium] gi|7162108|emb|CAB76676.1 NP_309680.1 similar to hypothetical proteins e.g. YciE [Escherichia coli] gi|775201|gb|AAA65179.1 NP_309681.1 similar to hypothetical proteins e.g. YciF [Escherichia coli] gi|140432|sp|P21362|YCIF_ECOLI NP_309682.1 similar to hypothetical proteins e.g. YciG-homolog [Salmonella typhimurium] gi|6851081|emb|CAB71036.1 NP_309683.1 similar to hypothetical proteins e.g. ybcY [Escherichia coli] gi|2495559|sp|P77460|YBCY_ECOLI NP_309684.1 similar to hypothetical proteins e.g. YlcE [Escherichia coli] gi|3025212|sp|P77087|YLCE_ECOLI NP_309685.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli O157:H7 EDL933] gi|3414881|gb|AAC31492.1 NP_309686.1 similar to hypothetical proteins e.g. L0014 [Escherichia coli O157:H7 EDL933] gi|3414882|gb|AAC31493.1 NP_309687.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 EDL933] gi|3414883|gb|AAC31494.1 NP_309689.1 similar to hypothetical protein [plasmid F] gi|8918853|dbj|BAA97900.1 NP_309690.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA NP_309691.1 similar to hypothetical proteins e.g. DNA binding protein [Streptomyces coelicolor A3(2)] gi|6855358|emb|CAB71249.1 NP_309692.1 OrfA; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_309693.1 OrfB; similar to transposase [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_309694.1 similar to hypothetical proteins e.g. part (1336-1569 in 1569 aa) of YPJA_ECOLI gi|2507221|sp|P52143 NP_309695.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell NP_309696.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums NP_309697.1 blocks the formation of polar Z-ring septums NP_309698.1 similar to YCGJ_ECOLI gi|1787425 (conserved in Escherichia coli K-12) NP_309699.1 similar to YCGK_ECOLI gi|1787426 (conserved in Escherichia coli K-12) NP_309701.2 similar to YCGL_ECOLI gi|1787427 (conserved in Escherichia coli K-12) NP_309702.1 similar to B1180_ECOLI gi|1787428 (conserved in Escherichia coli K-12) NP_309703.3 similar to YCGN_ECOLI gi|1787429 (conserved in Escherichia coli K-12) NP_309704.1 Acts by forming a pore-like structure upon contact with mammalian cells NP_309705.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization NP_309706.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization NP_309707.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein NP_309708.1 involved in regulation of intracellular pH under alkaline conditions NP_309709.1 Multifunctional regulator of fatty acid metabolism NP_309710.1 similar to YCGB_ECOLI gi|1787437 (conserved in Escherichia coli K-12) NP_309711.1 catalyzes the oxidative deamination of D-amino acids NP_309713.2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli NP_309714.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine NP_309715.1 similar to MLTE_ECOLI gi|1787442 (conserved in Escherichia coli K-12) NP_309716.1 OrfB; transposase insertion sequence IS629; similar to gi|7443862|pir|T00240 NP_309717.1 OrfA; transposase insertion sequence IS629; similar to hypothetical proteins. e.g. [Shigella flexneri SHI-2 pathogenicity island] gi|5532454|gb|AAD44738.1|AF141323_9 NP_309718.1 similar to f YCGR_ECOLI gi|1787443 NP_309719.1 similar to YMGE_ECOLI gi|1787445 (conserved in Escherichia coli K-12) NP_309720.1 similar to TonB dependent outer membrane receptor PrrA [Escherichia coli CFT073] gi|3661477|gb|AAC61709.1 NP_309721.1 involved in molybdenum transport NP_309724.1 similar to ferric enterobactin transport ATP-binding protein [Escherichia coli CFT073] gi|3661480|gb|AAC61712.1 NP_309725.1 permease; similar to ABC transporter permeases e.g. [Haemophilus influenzae] gi|2501391|sp|Q57130|YE71_HAEIN NP_309726.1 similar to iron (iii) ABC transporter, ATP-binding protein [Pyrococcus abyssi (strain Orsay)] gi|7519847|pir||A75077 NP_309730.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL NP_309731.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone NP_309732.3 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase NP_309733.1 similar to B1201_ECOLI (DhaR) gi|1787451|P76016 NP_309734.1 similar to adhesion and penetration protein B1202_ECOLI gi|1787452 (conserved in Escherichia coli K-12) NP_309735.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_309736.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_309737.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function NP_309738.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport NP_309739.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP NP_309740.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis NP_309741.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein NP_309742.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_309743.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_309744.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB NP_309745.1 similar to B1213_ECOLI gi|1787464 (conserved in Escherichia coli K-12) NP_309746.1 similar to YCHA_ECOLI gi|1787465 (conserved in Escherichia coli K-12) NP_309747.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis NP_309748.1 similar to CHAA_ECOLI gi|1787468 (conserved in Escherichia coli K-12) NP_309749.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions NP_309750.1 similar to CHAC_ECOLI gi|1787470 (conserved in Escherichia coli K-12) NP_309751.1 similar to YCHN_ECOLI gi|1787471 (conserved in Escherichia coli K-12) NP_309752.1 similar to YCHP_ECOLI gi|1787472 (conserved in Escherichia coli K-12) NP_309753.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase NP_309754.1 similar to NARX_ECOLI gi|1787474 (conserved in Escherichia coli K-12) NP_309755.1 similar to NARK_ECOLI gi|1787475 (conserved in Escherichia coli K-12) NP_309756.1 similar to NARG_ECOLI gi|1787477 (conserved in Escherichia coli K-12) NP_309757.1 similar to NARH_ECOLI gi|1787478 (conserved in Escherichia coli K-12) NP_309758.1 similar to NARJ_ECOLI gi|1787479 (conserved in Escherichia coli K-12) NP_309759.1 similar to NARI_ECOLI gi|1787480 (conserved in Escherichia coli K-12) NP_309760.1 similar to B1228_ECOLI gi|1787481 (conserved in Escherichia coli K-12) NP_309761.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine NP_309762.1 similar to YCHJ_ECOLI gi|1787484 (conserved in Escherichia coli K-12) NP_309763.1 similar to YCHK_ECOLI gi|1787485 (conserved in Escherichia coli K-12) NP_309764.1 similar to HNR_ECOLI gi|1787487 (conserved in Escherichia coli K-12) NP_309765.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose NP_309766.1 similar to HNS_ECOLI gi|1787489 (conserved in Escherichia coli K-12) NP_309767.1 catalyzes the formation of thymidine 5'-phosphate from thymidine NP_309768.1 similar to ADHE_ECOLI gi|1787493 (conserved in Escherichia coli K-12) NP_309769.1 similar to YCHE_ECOLI gi|1787494 (conserved in Escherichia coli K-12) NP_309770.1 similar to OPPA_ECOLI gi|1787495 (conserved in Escherichia coli K-12) NP_309771.1 similar to OPPB_ECOLI gi|1787497 (conserved in Escherichia coli K-12) NP_309772.1 similar to OPPC_ECOLI gi|1787498 (conserved in Escherichia coli K-12) NP_309773.1 similar to OPPD_ECOLI gi|1787499 (conserved in Escherichia coli K-12) NP_309774.1 similar to OPPF_ECOLI gi|1787500 (conserved in Escherichia coli K-12) NP_309775.2 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein NP_309776.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) NP_309777.1 similar to KCH_ECOLI gi|1787503 (conserved in Escherichia coli K-12) NP_309778.2 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity NP_309779.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins NP_309780.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins NP_309781.1 Involved in cell division; probably involved in intracellular septation NP_309782.1 similar to YCIC_ECOLI gi|1787508 (conserved in Escherichia coli K-12) NP_309783.1 receptor for colicin S4 NP_309784.1 similar to phage integrase [Bacteriophage 21] gi|138558|sp|P27077|VINT_BPP21 NP_309785.1 similar to excisionase [Bacteriophage 21] gi|139674|sp|P27079|VXIS_BPP21 NP_309786.1 similar to hypothetical protein ydfE [Escherichia coli cryptic prophage/truncated insertion sequence IS2 fusion] gi|78597|pir||S03698 NP_309787.1 similar to hypothetical protein YdfD [Escherichia coli] gi|140587|sp|P29010|YDFD_ECOLI NP_309788.1 similar to cell division inhibitor dicB [Escherichia coli] gi|2507009|sp|P09557|DICB_ECOLI; cell division inhibition protein NP_309791.1 similar to hypothetical 8.3 KD protein YdfC [Escherichia coli] gi|140586|sp|P21418|YDFC_ECOLI NP_309792.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown. NP_309793.1 probable repressor protein of division inhibition gene dicB; similar to DicC [Escherichia coli] gi|118633|sp|P06965|DICC_ECOLI NP_309794.1 similar to hypothetical 11.0 kDa protein YdfX [Escherichia coli] gi|3183265|sp|P76165|YDFX_ECOLI NP_309795.1 similar to replication termination factor (prepriming protein I) DnaT [Escherichia coli] gi|1361001|pir||S56589 NP_309796.1 similar to phage replication proteins e.g. protein 14 [phage phi-80] gi|137937|sp|P14814|VG14_BPPH8 NP_309799.1 similar to accessory colonization factor AcfC [Vibrio cholerae] gi|558481|gb|AAA50604.1, Anm (attachment and effacement of negative mutant) protein [Escherichia coli] gi|6715555|gb|AAB48445.2 NP_309800.1 probable toxic protein; similar to Hok/Gef family e.g. Gef [Escherichia coli] gi|2120017|pir||S40540 NP_309801.1 similar to Rem protein [Escherichia coli] gi|132324|sp|P07010|REM_ECOLI NP_309802.1 similar to orf QD1 [Bacteriophage N15] gi|2564084|gb|AAB81659.1 NP_309803.1 similar to hypothetical protein b1560 [Escherichia coli] gi|7466196|pir||C64911, hypothetical protein A [phage P1] gi|732234|sp|Q06262|YORA_BPP1 NP_309804.1 probable crossover junction endodeoxyribonuclease; similar to Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1, crossover junction endodeoxyribonucleases e.g. Rus [Escherichia coli cryptic lambdoid prophage NP_309806.1 similar to orf2 [Bacteriophage P27] gi|8346569|emb|CAB93762.1| NP_309807.1 similar to orf3 [Bacteriophage P27] gi|8346570|emb|CAB93763.1, adenine specific modification methylases e.g. Gp52 [phage N15] gi|7433503|pir||T13139 NP_309808.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_309809.1 similar to holin e.g. [Bacteriophage 933W] gi|4499808|emb|CAB39307.1 NP_309810.1 similar to hypothetical protein YdfR [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_309811.1 similar to endolysins e.g. [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45 NP_309812.1 similar to antirepressor protein Ant [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520, antirepressor protein Ant [Bacteriophage P22] gi|131843|sp|P03037|RANT_BPP22 NP_309813.1 endopeptidase (host lysis); similar to Rz [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1|, Rz endopeptidases e.g. [Bacteriophage lambda] gi|119368|sp|P00726|ENPP_LAMBD NP_309815.1 similar to hypothetical protein [Escherichia coli] gi|1778472|gb|AAB40755.1 NP_309816.1 similar to DNAse [Bacteriophage phi-C31] gi|1107475|emb|CAA62587.1 NP_309818.1 similar to terminase small subunit [Bacillus subtilis PBSX phage] gi|1722886|sp|P39785|XTMA_BACSU NP_309819.1 similar to phage D3 terminase-like protein [Haemophilus influenzae] gi|6739656|gb|AAF27357.1|AF198256_11 NP_309820.1 similar to prohead proteases e.g. [Bacteriophage HK97] gi|1722780|sp|P49860|VP4_BPHK7 NP_309822.1 similar to head portal proteins, e.g. [Bacteriophage HK022] gi|6863114|gb|AAF30355.1|AF069308_3 NP_309824.1 similar to head-tail adaptors e.g. [Bacteriophage HK97] gi|6901597|gb|AAF31100.1 NP_309825.1 similar to phage hypothetical proteins e.g. Gp10 [Bacteriophage HK97] gi|6901598|gb|AAF31101.1 NP_309826.1 similar to Gp11 [Bacteriophage HK97] gi|6901599|gb|AAF31102.1 NP_309827.1 similar to major tail subunit [Bacteriophage HK97] gi|6901588|gb|AAF31091.1|AF069529_4 NP_309828.1 similar to tail assembly chaperone Gp14 [Bacteriophage HK97] gi|6901600|gb|AAF31103.1 NP_309829.1 produced by translational frameshift; similar to C-terminal part of Gp14 [Bacteriophage HK97] gi|6901601|gb|AAF31104.1| NP_309830.1 similar to tail length tape measure proteins e.g. [Bacteriophage HK97] gi|6901589|gb|AAF31092.1|AF069529_5 NP_309831.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_309832.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_309833.1 similar to host specificity proteins e.g. GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_309834.1 similar to outer membrane protein Lom precursors e.g. [prophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2, [Bacteriophage lambda] gi|138693|sp|P03701|VLOM_LAMBD NP_309835.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_309836.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_309840.1 similar to integrases e.g. [Bacteriophage HK022] gi|138560|sp|P16407|VINT_BPHK0 NP_309845.1 similar to L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1| NP_309846.1 similar to L0014 [Escherichia coli O157:H7 strain EDL933] gi|3288157|emb|CAA11510.1| NP_309847.1 similar to L0013 [Escherichia coli O157:H7 strain EDL933] gi|3414881|gb|AAC31492.1| NP_309851.1 similar to hypothetical proteins e.g. orf2 [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1 NP_309852.1 similar to TrcA (bfpT-regulated chaperone-like protein) -like proteins e.g. TrcA [Escherichia coli strain B171-8] gi|4126789|dbj|BAA36747.1 NP_309856.1 similar to YCIE_ECOLI gi|1787511 (conserved in Escherichia coli K-12) NP_309857.1 similar to YCIF_ECOLI gi|1787512 (conserved in Escherichia coli K-12) NP_309858.2 similar to YCIG_ECOLI gi|1787513 (conserved in Escherichia coli K-12) NP_309859.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_309860.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_309861.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate NP_309862.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis NP_309863.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine NP_309865.1 similar to YCIV_ECOLI gi|1787520 (conserved in Escherichia coli K-12) NP_309866.3 similar to YCIO_ECOLI gi|1787521 (conserved in Escherichia coli K-12) NP_309867.1 similar to YCIQ_ECOLI gi|1787522, YCIQ_ECOLI gi|1787522 NP_309868.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA NP_309869.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide NP_309870.1 similar to YCIK_ECOLI gi|1787526 (conserved in Escherichia coli K-12) NP_309871.1 SohB; periplasmic protein; member of the peptidase S49 family NP_309872.1 similar to YCIN_ECOLI gi|1787528 (conserved in Escherichia coli K-12) NP_309873.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_309874.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation NP_309876.1 Catalyzes the conversion of citrate to isocitrate NP_309877.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate NP_309878.1 similar to PGPB_ECOLI gi|1787534 (conserved in Escherichia coli K-12) NP_309879.1 similar to YCIS_ECOLI gi|1787535 (conserved in Escherichia coli K-12) NP_309880.1 similar to YCIM_ECOLI gi|2367116 (conserved in Escherichia coli K-12) NP_309881.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase NP_309882.1 involved in start site selection during the initiation of translation NP_309883.1 similar to OSMB_ECOLI gi|1787539 (conserved in Escherichia coli K-12) NP_309884.1 similar to B1284_ECOLI gi|1787540 (conserved in Escherichia coli K-12) NP_309885.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP NP_309886.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction NP_309887.2 similar to YCIW_ECOLI gi|1787544 (conserved in Escherichia coli K-12) NP_309888.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_309889.1 similar to transcription regulatory proteins e.g. UidR [Escherichia coli] gi|2495429|sp|Q59431|UIDR_ECOLI NP_309890.1 similar to multidrug-efflux transport protein precursors e.g. AcrA [Escherichia coli K-12] gi|399000|sp|P31223|ACRA_ECOLI NP_309891.1 similar to multidrug-efflux transport proteins e.g. AcrB [Escherichia coli K-12] gi|399001|sp|P31224|ACRB_ECOLI NP_309892.1 similar to outer membrane channel proteins e.g. OprM [Pseudomonas aeruginosa] gi|3184190|dbj|BAA28694.1 NP_309893.1 similar to membrane transport proteins e.g. [Streptomyces coelicolor A3(2)] gi|6469269|emb|CAB61730.1 NP_309894.1 similar to SAPF_ECOLI gi|1787547 (conserved in Escherichia coli K-12) NP_309895.1 similar to SAPD_ECOLI gi|1787548 (conserved in Escherichia coli K-12) NP_309896.1 similar to SAPC_ECOLI gi|1787549 (conserved in Escherichia coli K-12) NP_309897.1 similar to SAPB_ECOLI gi|1787550 (conserved in Escherichia coli K-12) NP_309898.1 periplasmic protein; similar to SAPA_ECOLI gi|1787551 (conserved in Escherichia coli K-12) NP_309899.1 similar to YMJA_ECOLI gi|1787552 (conserved in Escherichia coli K-12) NP_309900.2 similar to YCJJ_ECOLI gi|1787553 (conserved in Escherichia coli K-12) NP_309901.2 similar to B1297_ECOLI gi|1787555 (conserved in Escherichia coli K-12) NP_309902.2 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate NP_309903.1 regulates genes involved in putrescine degradation NP_309904.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation NP_309905.1 similar to ORDL_ECOLI gi|1787559 (conserved in Escherichia coli K-12) NP_309906.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate NP_309907.2 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor NP_309908.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF NP_309909.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding NP_309910.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock NP_309911.1 similar to PSPD_ECOLI gi|1787565 (conserved in Escherichia coli K-12) NP_309912.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide NP_309917.1 similar to YCJO_ECOLI gi|1787570 (conserved in Escherichia coli K-12) NP_309918.1 similar to YCJP_ECOLI gi|1787571 (conserved in Escherichia coli K-12) NP_309919.1 similar to YCJQ_ECOLI gi|1787572 (conserved in Escherichia coli K-12) NP_309920.1 similar to B1314_ECOLI gi|1787573 (conserved in Escherichia coli K-12) NP_309921.1 similar to YCJS_ECOLI gi|1787574 (conserved in Escherichia coli K-12) NP_309922.1 similar to YCJT_ECOLI gi|1787575 (conserved in Escherichia coli K-12) NP_309923.1 similar to YCJU_ECOLI gi|1787576 (conserved in Escherichia coli K-12) NP_309924.1 similar to ABC transporter ATP-binding protein YCJV_ECOLI gi|1787577 (conserved in Escherichia coli K-12) NP_309925.1 similar to OMPG_ECOLI gi|1787579 (conserved in Escherichia coli K-12) NP_309926.1 similar to YCJW_ECOLI gi|1787580 (conserved in Escherichia coli K-12) NP_309927.1 similar to YCJX_ECOLI gi|1787581 (conserved in Escherichia coli K-12) NP_309928.1 similar to YCJF_ECOLI gi|1787582 (conserved in Escherichia coli K-12) NP_309929.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids NP_309930.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein NP_309931.2 similar to YCJG_ECOLI gi|1787585 (conserved in Escherichia coli K-12) NP_309932.1 similar to YCJI_ECOLI gi|1787586 (conserved in Escherichia coli K-12) NP_309933.2 similar to hypothetical protein [Xylella fastidiosa] gi|9106817|gb|AAF84556.1|AE003997_12 NP_309936.1 similar to B1327_ECOLI gi|1787587 (conserved in Escherichia coli K-12) NP_309937.1 similar to YCJZ_ECOLI gi|1787589 (conserved in Escherichia coli K-12) NP_309938.2 similar to B1329_ECOLI gi|1787590 (conserved in Escherichia coli K-12) NP_309939.1 similar to B1330_ECOLI gi|1787591 (conserved in Escherichia coli K-12) NP_309940.1 similar to YNAJ_ECOLI gi|1787593 (conserved in Escherichia coli K-12) NP_309941.1 with UspC and UspD is involved in resistance to UV irradiation NP_309942.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia NP_309943.1 similar to OGT_ECOLI gi|1787596 (conserved in Escherichia coli K-12) NP_309944.1 similar to C-terminal part (307-510 in 510 aa) of pump protein YDAH_ECOLI gi|1787597 NP_309945.1 OrfB; transposase of insertion sequence IS629; similar to gi|7443862|pir||T00240 NP_309946.1 OrfA; transposase of insertion sequence IS629; similar to gi|7444868|pir||T00241 NP_309947.1 similar to YDAH_ECOLI gi|1787597; may be truncated NP_309948.1 similar to B1337_ECOLI gi|1787598 (conserved in Escherichia coli K-12) NP_309949.2 similar to YDAJ_ECOLI gi|1787599 (conserved in Escherichia coli K-12) NP_309950.1 similar to YDAK_ECOLI gi|1787601 (conserved in Escherichia coli K-12) NP_309951.1 similar to YDAL_ECOLI gi|1787602 (conserved in Escherichia coli K-12) NP_309952.1 similar to B1341_ECOLI gi|1787603 (conserved in Escherichia coli K-12) NP_309953.1 similar to B1342_ECOLI gi|1787604 (conserved in Escherichia coli K-12) NP_309954.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA NP_309955.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs NP_309956.1 similar to B1345_ECOLI gi|1787607 (conserved in Escherichia coli K-12) NP_309957.2 similar to YDAQ_ECOLI gi|1787608 (conserved in Escherichia coli K-12) NP_309958.1 Rac prophage NP_309959.1 seems to be involved in restriction alleviation and enhancement of modification by EcoKI, but not in restriction alleviation of type III restriction systems; Rac prophage NP_309960.1 similar to RECT_ECOLI gi|1787611 (conserved in Escherichia coli K-12) NP_309961.1 The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC. NP_309962.1 Rac prophage hypothetical protein NP_309963.1 Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division NP_309964.2 similar to SIEB_ECOLI gi|1787616 (conserved in Escherichia coli K-12) NP_309965.1 similar to YDAF_ECOLI in sieB-racR intergenic region gi|3915965|sp|P38395 (not identified but conserved in K-12) NP_309967.1 similar to B1355_ECOLI gi|1787618 (conserved in Escherichia coli K-12) NP_309968.1 similar to regulatory proteins e.g. regulatory protein CI (235 aa) [Bacteriophage HK022] gi|1350835|sp|P18680 NP_309969.1 similar to Cro [Bacteriophage HK022] gi|1350553|sp|P18679 NP_309970.1 similar to YDAT_ECOLI gi|1787621 (conserved in Escherichia coli K-12) NP_309971.1 similar to YDAU_ECOLI gi|1787622 NP_309972.1 acts to load the DnaB helicase onto the intiation site durning DNA replication NP_309973.1 similar to YDAW_ECOLI gi|1787624 NP_309978.1 similar to EaA protein [Bacteriophage P22] gi|418207|sp|Q03544|VEAA_BPP22 NP_309979.1 similar to hypothetical protein [Bacteriophage H19J] gi|4490348|emb|CAB38711.1, Gp45 [Bacteriophage N15] gi|7521552|pir||T13131 NP_309980.1 similar to methyltransferases e.g. cytosine-specific methyltransferase XorII [Xanthomonas oryzae pv.] gi|1709171|sp|P52311|MTX2_XANOR NP_309981.1 similar to hypothetical protein HI0983 [Haemophilus influenzae] gi|1074592|pir||D64163 NP_309983.1 similar to Orf79 [Bacteriophage D3] gi|8895177|gb|AAF80835.1 NP_309984.1 similar to hypothetical proteins e.g. YbcO [Escherichia coli cryptic prophage DLP12] gi|7467043|pir||C64787, Gp66 [Bacteriophage HK97] gi|6901638|gb|AAF31141.1 NP_309985.1 similar to antiterminator protein Q [Bacteriophage 21] gi|4539484|emb|CAB39993.1 NP_309986.1 similar to probable TerB proteins e.g. [Deinococcus radiodurans] gi|7473690|pir||C75302 NP_309988.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_309989.1 host cell lysis; similar to holins e.g. [Bacteriophage 933W] gi|4499808|emb|CAB39307.1 NP_309990.1 similar to hypothetical protein [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_309991.1 host cell lysis; similar to endolysins e.g. [Bacteriophage 933W] gi|4335686|gb|AAD17382.1 NP_309992.1 similar to antirepressor [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46, antirepressor protein Ant [Bacteriophage P22] gi|131843|sp|P0 NP_309993.1 host cell lysis; similar to endopeptidases e.g. [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1 NP_309994.1 similar to hypothetical protein [Escherichia coli] gi|1778472|gb|AAB40755.1, hypothetical protein [Salmonella dublin] gi|3511132|gb|AAC33722.1 NP_309995.1 similar to TerF-related protein [Deinococcus radiodurans] gi|7473956|pir||C75599, gp30 (DNase) [Bacteriophage phi-C31] gi|1107475|emb|CAA62587.1 NP_309997.1 similar to phage terminase small subunits e.g. [Bacillus subtilis PBSX] gi|1722886|sp|P39785|XTMA_BACSU NP_309998.1 similar to phage hypothetical proteins, e.g. phage D3 terminase-like protein [Haemophilus influenzae] gi|6739656|gb|AAF27357.1|AF198256_11 NP_309999.1 similar to major head proteins e.g. [Mycobacterium phage L5] gi|465114|sp|Q05223|VG17_BPML5 NP_310001.1 similar to phage portal proteins e.g. [Bacteriophage D3] gi|5059250|gb|AAD38955.1 NP_310004.1 similar to head-tail adaptors e.g. [Bacteriophage HK97] gi|6901597|gb|AAF31100.1 NP_310005.1 similar to phage hypothetical proteins e.g. Gp10 [Bacteriophage HK97] gi|6901598|gb|AAF31101.1 NP_310006.1 similar to Gp11 [Bacteriophage HK97] gi|6901599|gb|AAF31102.1 NP_310007.1 similar to major tail subunit [Bacteriophage HK97] gi|6901588|gb|AAF31091.1|AF069529_4 NP_310008.1 similar to tail assembly chaperon Gp14 [Bacteriophage HKJ97] gi|6901600|gb|AAF31103.1 NP_310009.1 similar to Gp14 [Bacteriophage HK97] gi|6901601|gb|AAF31104.1; may be produced by translational frameshift NP_310010.1 similar to tail length tape measure proteins e.g. [Bacteriophage HK97] gi|6901589|gb|AAF31092.1|AF069529_5 NP_310011.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_310012.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_310013.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|6901605|gb|AAF31108.1 NP_310014.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_310016.1 similar to copper/zinc-superoxide dismutases e.g. [Salmonella typhimurium] gi|2462699|emb|CAA73588.1 NP_310017.1 similar to host specificity proteins e.g. GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_310018.1 similar to outer membrane proteins e.g. Lom protein [Bacteriophage P-EibA] dad|AF151091-2|AAF63231.1 NP_310019.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 (AF125520) NP_310020.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_310021.1 similar to ORF4 [Escherichia coli strain B171-8] gi|4126792|dbj|BAA36750.1, ORF2 [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1 NP_310022.1 similar to ORF4 [Escherichia coli strain B171-8] gi|4126792|dbj|BAA36750.1, ORF2 [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1 NP_310023.1 similar to ORF4 [Escherichia coli B171-8] gi|4126792|dbj|BAA36750.1, ORF2 [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1 NP_310024.2 similar to YNAF_ECOLI gi|1787640 (conserved in Escherichia coli K-12) NP_310027.1 similar to YDBK_ECOLI gi|1787642 (conserved in Escherichia coli K-12) NP_310028.1 heat shock protein; similar to HSLJ_ECOLI gi|1787644 (conserved in Escherichia coli K-12) NP_310029.1 Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes NP_310030.1 similar to YDBH_ECOLI gi|1787646 (conserved in Escherichia coli K-12) NP_310031.1 similar to YNBE_ECOLI gi|1787647 (conserved in Escherichia coli K-12) NP_310032.1 similar to YDBL_ECOLI gi|1787648 NP_310033.1 similar to BigA protein [Salmonella typhi] dad|AF133185-1|AAD29677.1, YdbA.2 [Escherichia coli] gi|7465766|pir||C48399 NP_310034.1 similar to BigB protein [Salmonella typhi] dad|AF133185-2|AAD29678.1, YdbA.2 [Escherichia coli] gi|7465766|pir||C48399 NP_310035.1 similar to YDBC_ECOLI gi|1787674 (conserved in Escherichia coli K-12) NP_310036.1 similar to YDBD_ECOLI gi|1787675 (conserved in Escherichia coli K-12) NP_310037.2 similar to B1408_ECOLI gi|1787676 (conserved in Escherichia coli K-12) NP_310038.1 similar to B1409_ECOLI gi|1787677 (conserved in Escherichia coli K-12) NP_310039.1 similar to B1410_ECOLI gi|1787678 (conserved in Escherichia coli K-12) NP_310040.1 similar to YNBD_ECOLI gi|1787679 (conserved in Escherichia coli K-12) NP_310041.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds NP_310042.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain NP_310047.1 similar to YDCF_ECOLI gi|1787683 (conserved in Escherichia coli K-12) NP_310048.1 NAD-linked NP_310049.1 similar to G3P3_ECOLI sp|P33898 NP_310050.2 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm NP_310051.1 similar to YDCA_ECOLI gi|1787688 (conserved in Escherichia coli K-12) NP_310052.1 similar to B1420_ECOLI gi|1787689 (conserved in Escherichia coli K-12) NP_310053.1 similar to TRG_ECOLI gi|1787690 (conserved in Escherichia coli K-12) NP_310054.2 similar to B1422_ECOLI gi|1787691 (conserved in Escherichia coli K-12) NP_310055.1 similar to B1423_ECOLI gi|1787692 (conserved in Escherichia coli K-12) NP_310056.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans NP_310057.1 similar to B1425_ECOLI gi|1787694 (conserved in Escherichia coli K-12) NP_310058.2 similar to YDCH_ECOLI gi|1787696 (conserved in Escherichia coli K-12) NP_310059.1 similar to RIML_ECOLI gi|1787697; interrupted NP_310060.1 similar to B1428_ECOLI gi|1787698 (conserved in Escherichia coli K-12) NP_310061.1 similar to TEHA_ECOLI gi|1787699 (conserved in Escherichia coli K-12) NP_310062.1 with TehA confers resistance to tellurite NP_310063.1 similar to B1431_ECOLI gi|1787701 (conserved in Escherichia coli K-12) NP_310064.2 similar to membrane transport protein B1433_ECOLI gi|1787703 (conserved in Escherichia coli K-12) NP_310065.1 similar to YDCN_ECOLI gi|1787704 (conserved in Escherichia coli K-12) NP_310066.1 similar to YDCP_ECOLI gi|1787705 (conserved in Escherichia coli K-12) NP_310067.1 similar to B1436_ECOLI gi|1787707 (conserved in Escherichia coli K-12) NP_310068.1 similar to B1437_ECOLI gi|1787708 (conserved in Escherichia coli K-12) NP_310069.1 similar to B1438_ECOLI gi|1787709 (conserved in Escherichia coli K-12) NP_310070.1 similar to B1439_ECOLI gi|1787710 (conserved in Escherichia coli K-12) NP_310071.1 similar to B1440_ECOLI gi|1787711 (conserved in Escherichia coli K-12) NP_310072.1 similar to B1441_ECOLI gi|1787712 (conserved in Escherichia coli K-12) NP_310073.1 similar to B1442_ECOLI gi|1787713 (conserved in Escherichia coli K-12) NP_310074.1 similar to B1443_ECOLI gi|1787714 (conserved in Escherichia coli K-12) NP_310075.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation NP_310076.1 similar to B1445_ECOLI gi|1787716 (conserved in Escherichia coli K-12) NP_310077.1 similar to B1446_ECOLI gi|1787717 (conserved in Escherichia coli K-12) NP_310078.1 similar to B1447_ECOLI gi|1787718 (conserved in Escherichia coli K-12) NP_310079.1 similar to B1448_ECOLI gi|1787719 (conserved in Escherichia coli K-12) NP_310080.2 similar to YNCB_ECOLI gi|1787721 (conserved in Escherichia coli K-12) NP_310081.2 similar to B1450_ECOLI gi|1787722 (conserved in Escherichia coli K-12) NP_310082.1 similar to B1451_ECOLI gi|1787723 (conserved in Escherichia coli K-12) NP_310083.1 similar to B1452_ECOLI gi|1787724 (conserved in Escherichia coli K-12) NP_310084.2 similar to ANSP_ECOLI gi|1787725 (conserved in Escherichia coli K-12) NP_310085.1 similar to B1454_ECOLI gi|1787726 (conserved in Escherichia coli K-12) NP_310086.1 similar to B1455_ECOLI gi|1787727 NP_310087.1 similar to Vgr proteins e.g. VgrE protein [Escherichia coli] gi|2920625|gb|AAC32465.1 NP_310088.1 core protein with extension; similar to Rhs core proteins e.g. RhsD [Escherichia coli] gi|1786706 (conserved in Escherichia coli K-12) NP_310091.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown NP_310092.1 similar to B1462_ECOLI gi|1787735 (conserved in Escherichia coli K-12) NP_310093.1 similar to N-hydroxyarylamine O-acetyltransferase B1463_ECOLI gi|1787736 NP_310094.1 similar to YDDE_ECOLI gi|1787737 (conserved in Escherichia coli K-12) NP_310095.1 similar to NARV_ECOLI gi|1787738 (conserved in Escherichia coli K-12) NP_310096.1 similar to NARW_ECOLI gi|1787739 (conserved in Escherichia coli K-12) NP_310097.1 similar to NARY_ECOLI gi|1787740 (conserved in Escherichia coli K-12) NP_310098.1 similar to NARG_ECOLI gi|1787477 (conserved in Escherichia coli K-12) NP_310099.1 similar to NARU_ECOLI gi|1787743 (conserved in Escherichia coli K-12) NP_310100.1 similar to B1471_ECOLI gi|1787745, B1470_ECOLI gi|1787744 NP_310101.1 similar to glycoprotein B1471_ECOLI gi|1787745 NP_310102.1 similar to IpaH protein IPA7_SHIFL gi|124813|sp|P18014, YDDK_ECOLI gi|3183258|sp|P76123 NP_310103.1 similar to outer membrane porin precursors e.g. NMPC_ECOLI gi|1786765 NP_310104.3 similar to YDDG_ECOLI gi|1787747 (conserved in Escherichia coli K-12) NP_310105.1 similar to FDNG_ECOLI gi|3868719 (conserved in Escherichia coli K-12) NP_310106.1 similar to FDOH_ECOLI gi|1790326 (conserved in Escherichia coli K-12) NP_310107.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase NP_310108.2 similar to YDDM_ECOLI gi|1787751 (conserved in Escherichia coli K-12) NP_310109.2 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs NP_310110.2 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate NP_310111.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase NP_310112.2 similar to B1481_ECOLI gi|1787756 (conserved in Escherichia coli K-12) NP_310113.1 similar to OSMC_ECOLI gi|1787757 (conserved in Escherichia coli K-12) NP_310114.1 similar to B1483_ECOLI gi|1787758 (conserved in Escherichia coli K-12) NP_310115.1 similar to B1484_ECOLI gi|1787759 (conserved in Escherichia coli K-12) NP_310116.1 similar to B1485_ECOLI gi|1787760 (conserved in Escherichia coli K-12) NP_310117.1 similar to transport system permease B1486_ECOLI gi|1787761 NP_310118.1 similar to B1487_ECOLI gi|1787762 (conserved in Escherichia coli K-12) NP_310119.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis NP_310122.1 similar to B1490_ECOLI gi|1787766 (conserved in Escherichia coli K-12) NP_310123.1 similar to B1491_ECOLI gi|1787767 (conserved in Escherichia coli K-12) NP_310124.1 similar to XASA_ECOLI gi|1787768 (conserved in Escherichia coli K-12) NP_310125.1 similar to GADB_ECOLI gi|1787769 (conserved in Escherichia coli K-12) NP_310126.1 similar to PQQL_ECOLI gi|1787770 (conserved in Escherichia coli K-12) NP_310127.1 similar to YDDB_ECOLI gi|1787771 (conserved in Escherichia coli K-12) NP_310128.1 similar to YDDA_ECOLI gi|1787772 (conserved in Escherichia coli K-12) NP_310129.2 similar to B1497_ECOLI gi|1787774 (conserved in Escherichia coli K-12) NP_310130.1 similar to B1498_ECOLI gi|1787775 (conserved in Escherichia coli K-12) NP_310131.1 regulates the cellular response to acid resistance NP_310132.1 similar to B1500_ECOLI gi|1787777 (conserved in Escherichia coli K-12) NP_310133.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase NP_310134.1 similar to B1502_ECOLI gi|1787779 (conserved in Escherichia coli K-12) NP_310135.1 similar to B1503_ECOLI gi|1787780 (conserved in Escherichia coli K-12) NP_310136.1 similar to B1504_ECOLI gi|1787781 (conserved in Escherichia coli K-12) NP_310137.1 similar to B1505_ECOLI gi|1787782 (conserved in Escherichia coli K-12) NP_310139.1 similar to fimbrial chaperone protein precursors e.g. FocC [Escherichia coli] gi|1169720|sp|P46008|FOCC_ECOLI NP_310140.1 similar to type 1 fimbrial protein precursors e.g. [Escherichia coli] gi|729528|sp|P04128|FM1A_ECOLI NP_310142.1 similar to DNA-binding regulator HIPA_ECOLI gi|1787785 NP_310143.1 similar to B1509_ECOLI gi|1787787 (conserved in Escherichia coli K-12) NP_310144.1 similar to YDEK_ECOLI gi|1787788 (conserved in Escherichia coli K-12) NP_310145.3 similar to YDEV_ECOLI gi|1787789 (conserved in Escherichia coli K-12) NP_310146.1 similar to YDEW_ECOLI gi|1787791 (conserved in Escherichia coli K-12) NP_310147.1 similar to B1513_ECOLI gi|1787792 (conserved in Escherichia coli K-12) NP_310148.1 similar to YDEY_ECOLI gi|1787793 (conserved in Escherichia coli K-12) NP_310149.1 similar to YDEZ_ECOLI gi|1787794 (conserved in Escherichia coli K-12) NP_310150.1 similar to B1516_ECOLI gi|1787795 (conserved in Escherichia coli K-12) NP_310151.1 similar to YNEB_ECOLI gi|1787796 (conserved in Escherichia coli K-12) NP_310152.1 similar to B1518_ECOLI gi|1787797 (conserved in Escherichia coli K-12) NP_310153.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate NP_310154.1 similar to B1520_ECOLI gi|1787799 (conserved in Escherichia coli K-12) NP_310155.1 catalyzes the formation of D-tagaturonate from D-altronate NP_310156.1 similar to B1522_ECOLI gi|1787802 (conserved in Escherichia coli K-12) NP_310157.1 similar to B1523_ECOLI gi|1787803 (conserved in Escherichia coli K-12) NP_310158.1 catalyzes the formation of glutamate from glutamine NP_310159.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase NP_310160.1 similar to YNEJ_ECOLI gi|1787806 (conserved in Escherichia coli K-12) NP_310161.1 similar to B1527_ECOLI gi|1787807 NP_310162.1 similar to YDEA_ECOLI gi|1787808 (conserved in Escherichia coli K-12) NP_310163.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function NP_310164.2 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes NP_310165.2 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF NP_310166.1 similar to MARB_ECOLI gi|1787812 (conserved in Escherichia coli K-12) NP_310167.1 similar to YDED_ECOLI gi|1787813 (conserved in Escherichia coli K-12) NP_310168.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters NP_310170.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism NP_310171.1 similar to YDEH_ECOLI gi|1787816 (conserved in Escherichia coli K-12) NP_310172.1 similar to YDEI_ECOLI gi|1787817 (conserved in Escherichia coli K-12) NP_310173.1 similar to YDEJ_ECOLI gi|1787818 (conserved in Escherichia coli K-12) NP_310174.1 similar to DCP_ECOLI gi|1787819 (conserved in Escherichia coli K-12) NP_310175.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine NP_310176.1 similar to YDFH_ECOLI gi|1787821 (conserved in Escherichia coli K-12) NP_310177.1 similar to B1541_ECOLI gi|1787822 (conserved in Escherichia coli K-12) NP_310178.1 similar to YDFI_ECOLI gi|1787823 (conserved in Escherichia coli K-12) NP_310179.1 similar to B1543_ECOLI gi|1787824 (conserved in Escherichia coli K-12) NP_310180.1 similar to damage-inducible proteins e.g. DinI [Escherichia coli] gi|2498305|sp|Q47143|DINI_ECOLI NP_310181.1 similar to hypothetical proteins e.g. ORF4 [Escherichia coli] gi|4126792|dbj|BAA36750.1, ORF2 [Escherichia coli] gi|4126790|dbj|BAA36748.1 NP_310182.1 similar to hypothetical proteins e.g. ORF4 [Escherichia coli] gi|4126790|dbj|BAA36748.1, ORF2 [Escherichia coli] gi|4126792|dbj|BAA36750.1 NP_310183.1 similar to hypothetical proteins e.g. ORF4 [Escherichia coli] gi|4126792|dbj|BAA36750.1, ORF2 [Escherichia coli] gi|4126790|dbj|BAA36748.1 NP_310184.1 similar to hypothetical protein[Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_310186.2 similar to tail fiber proteins e.g. Gp37 [Escherichia coli] gi|7466858|pir||G64887, orf-401 [Bacteriophage lambda] gi|140053|sp|P03764|Y401_LAMBD NP_310187.1 similar to Lom-like proteins e.g.[prophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2, Lom [Bacteriophage lambda] gi|138693|sp|P03701|VLOM_LAMBD NP_310188.1 host specificity protein; similar to host specificity proteins e.g. GpJ [Bacteriophage lambda] gi|138412|sp|P03749|VHSJ_LAMBD NP_310189.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_310190.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda gi|139638|sp|P03729|VTAK_LAMBD NP_310191.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_310192.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_310193.1 similar to tail length tape measure protein precursors e.g. GpH [Bacteriophage lambda] gi|138843|sp|P03736|VMTH_LAMBD NP_310194.1 similar to minor tail proteins e.g. GpG-T [Bacteriophage lambda] gi|7429179|pir||TLBPTL; may be produced by translational frameshift NP_310195.1 similar to minor tail proteins e.g. GpG [Bacteriophage lambda] gi|138842|sp|P03734|VMTG_LAMBD NP_310196.1 similar to protein V Bacteriophage lambda NP_310197.1 similar to minor tail proteins GpU [Bacteriophage lambda] gi|138847|sp|P03732|VMTU_LAMBD NP_310198.1 similar to minor tail proteins e.g. GpZ [Bacteriophage lambda] gi|138849|sp|P03731|VMTZ_LAMBD NP_310199.1 minor capsid protein; similar to minor capsid proteins e.g. GpFII [Bacteriophage lambda] gi|137575|sp|P03714|VCF2_LAMBD NP_310200.1 similar to DNA-packaging proteins e.g. GpFI [Bacteriophage lambda] gi|139324|sp|P03709|VPF1_LAMBD NP_310201.1 similar to major capsid proteins e.g. GpE [Bacteriophage lambda] gi|116701|sp|P05481|HEAD_BPPH8 NP_310202.1 major capsid protein; similar to major capsid proteins e.g. GpD [Bacteriophage lambda] gi|137566|sp|P03712|VCAD_LAMBD NP_310203.1 similar to minor capsid protein precursors e.g. GpC [Bacteriophage lambda] gi|137565|sp|P03711|VCAC_LAMBD; contains capsid assembly protein Nu3-homolog NP_310204.1 minor capsid protein; similar to portal proteins e.g. GpB [Bacteriophage lambda] gi|138762|sp|P03710|VMCB_LAMBD NP_310205.1 similar to head-to-tail joining proteins e.g. GpW [Bacteriophage lambda] gi|138415|sp|P03727|VHTJ_LAMBD NP_310206.1 DNA-packaging protein; similar to terminase large subunits e.g. GpA [Bacteriophage lambda] gi|137616|sp|P03708|TERL_LAMBD NP_310207.1 similar to terminase small subunits e.g. Nu1 [Bacteriophage lambda] NP_310208.1 similar to hypothetical protein [Escherichia coli] gi|1778472|gb|AAB40755.1 NP_310209.1 similar to PerC (BfpW) transcriptional activator of eaeA/bfpA [Escherichia coli] gi|1172431|sp|P43475|PERC_ECOLI NP_310210.1 host cell lysis; similar to endopeptidases e.g. [Bacteriophage H-19B] gi|4335687|gb|AAD17383.1 NP_310212.1 similar to antirepressors e.g. [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46 NP_310213.1 host cell lysis; similar to endolysins e.g. [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45 NP_310214.1 similar to hypothetical protein gi|3183262|sp|P76160|YDFR_ECOLI NP_310215.1 similar to holins e.g. [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1 NP_310216.1 similar to hypothetical proteins [Bacteriophage VT2-Sa] gi|5881634|dbj|BAA84325.1 NP_310217.1 similar to tellurium resistance protein TerB proteins e.g. [Deinococcus radiodurans] gi|7473690|pir||C75302 NP_310218.1 similar to transcriptional regulators e.g. [Escherichia coli] gi|586679|sp|P37638|YHIW_ECOLI NP_310219.1 similar to hypothetical protein [Bacteriophage P27] gi|8346569|emb|CAB93762.1 NP_310220.1 similar to Q protein [Bacteriophage 21] gi|7440086|pir||D71566 NP_310221.1 similar crossover junction endodeoxyribonuclease [Escherichia coli] gi|2507117|sp|P40116|RUS_ECOLI, Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1 NP_310222.1 similar to B1560_ECOLI gi|1787843 NP_310224.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585451|gb|AAD25479.1|AF125520_74, Ygi [Escherichia coli] gi|1723887|sp|P52083|YGIW_ECOLI NP_310225.1 prophage maintenance protein; similar to MokW [Bacteriophage 933W] gi|4585453|gb|AAD25481.1|AF125520_76, Hok/Gef family e.g. Gef [Escherichia coli] gi|2120017|pir||S40540 NP_310226.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585382|gb|AAD25410.1|AF125520_5 NP_310227.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585384|gb|AAD25412.1|AF125520_7 NP_310230.1 similar to Gp9 [Bacteriophage Mu] gi|6010430|gb|AAF01133.1|AF083977_54 NP_310231.1 similar to hypothetical protein YdaW [Escherichia coli] gi|3025105|sp|P76066|YDAW_ECOLI NP_310232.1 similar to C-terminal half of replication protein 14 [Bacteriophage phi-80] gi|137937|sp|P14814|VG14_BPPH8 NP_310233.1 similar to DnaT [Escherichia coli] gi|1361001|pir||S56589 NP_310234.1 similar to hypothetical protein [Escherichia coli] gi|3025103|sp|P76064|YDAT_ECOLI NP_310235.1 similar to Cro [Bacteriophage P22] gi|132195|sp|P09964|RCRO_BPP22 NP_310236.1 similar to repressor proteins e.g. C2 [Bacteriophage P22] gi|133359|sp|P03035|RPC2_BPP22 NP_310237.1 similar to hypothetical proteins e.g. YdfK [Escherichia coli] gi|140584|sp|P29008|YDFA_ECOLI, YdaF gi|3915965|sp|P38395|YDAF_ECOLIF NP_310238.1 similar to ATP-dependent protease La homolog gi|1708857|sp|P42425|LON2_BACSU NP_310241.1 similar to DicB [Escherichia coli] gi|226094|prf||1410309A NP_310242.1 similar to hypothetical protein YdfD [Escherichia coli] gi|140587|sp|P29010|YDFD_ECOLI NP_310243.1 similar to exonucleases e.g. exodeoxyribonuclease VIII [Escherichia coli] gi|2507105|sp|P15032|RECE_ECOLI NP_310244.1 similar to N-terminal part of integrases e.g. [Escherichia coli cryptic prophage] gi|7449509|pir||E64913 NP_310246.1 OrfB of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 IS629] gi|7443862|pir||T00240 NP_310247.1 OrfA of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_310248.1 similar to transposases e.g. [Yersinia pestis plasmid pMT1] gi|7447905|pir||T14710 NP_310249.1 similar to L0013 [Escherichia coli O157:H7 strain EDL933] gi|3414881|gb|AAC31492.1, hypothetical proteins e.g. Hp3 [Escherichia coli strain CFT073] gi|3661484|gb|AAC61715.1 NP_310250.1 similar to L0014 [Escherichia coli O157:H7 strain EDL933] gi|3288157|emb|CAA11510.1, hypothetical proteins e.g. Orf50 [Escherichia coli strain B171] gi|6009426|dbj|BAA84885.1 NP_310251.1 similar to L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1, hypothetical protein [Escherichia coli plasmid pColV-K30] gi|3288156|emb|CAA11509.1 NP_310253.1 similar to hypothetical proteins e.g. ORF2 in trcA region [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1, ORF4 in trcA region [Escherichia coli strain B171-8] gi|4126792|dbj|BAA36750.1 NP_310254.1 similar to hypothetical protein [Lactococcus bacteriophage c2] gi|1146281|gb|AAA92162.1| NP_310256.1 similar to hypothetical proteins e.g. ORF4 in trcA region [Escherichia coli strain B171-8] gi|4126792|dbj|BAA36750.1, ORF2 in trcA region [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1 NP_310257.1 similar to hypothetical protein [Bacteriophage 933W] gi|7649887|dbj|BAA94165.1 NP_310258.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_310259.1 similar to Lom outer membrane proteins e.g. [Bacteriophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2 NP_310263.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_310264.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_310265.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_310266.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_310267.1 similar to tail length tape measure proteins e.g. [Bacteriophage HK97] gi|6901589|gb|AAF31092.1|AF069529_5 NP_310268.1 similar to Gp14 [Bacteriophage HK97] gi|6901601|gb|AAF31104.1; may be produced by translational frameshift NP_310269.1 similar to tail assembly chaperone [Bacteriophage HK97] gi|6901600|gb|AAF31103.1 NP_310270.1 similar to major tail subunit [Bacteriophage HK97] gi|6901588|gb|AAF31091.1|AF069529_4 NP_310271.1 similar to Gp11 [Bacteriophage HK97] gi|6901599|gb|AAF31102.1 NP_310272.1 similar to phage hypothetical proteins Gp10 [Bacteriophage HK97] gi|6901598|gb|AAF31101.1 NP_310273.1 similar to head-tail adaptors e.g. [Bacteriophage HK97] gi|6901597|gb|AAF31100.1 NP_310275.1 similar to portal proteins e.g. [Bacteriophage D3] gi|5059250|gb|AAD38955.1 NP_310277.1 similar to prohead proteases e.g. [Rhodobacter capsulatus] gi|6467535|gb|AAF13181.1|AF181080_3 NP_310278.1 similar to hypothetical proteins e.g. phage D3 terminase-like protein [Haemophilus influenzae] gi|6739656|gb|AAF27357.1|AF198256_11 NP_310279.1 similar to terminase small subunit - PBSX phage Bacillus subtilis gi|1722886|sp|P39785|XTMA_BACSU NP_310281.1 similar to DNase [Bacteriophage phi-C31] gi|1107475|emb|CAA62587.1 NP_310282.1 similar to hypothetical protein [Escherichia coli] gi|1778472|gb|AAB40755.1 NP_310283.1 cell lysis; similar to Rz [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1, Rz endopeptidases e.g. [Bacteriophage lambda] gi|119368|sp|P00726|ENPP_LAMBD NP_310285.1 similar to Ant [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46, antirepressor Ant [Bacteriophage P22] gi|131843|sp|P03037|RANT_BPP22 NP_310286.1 similar to endolysins e.g. [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45 NP_310287.1 similar to hypothetical protein YdfR (103 aa) [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_310288.1 similar to holins e.g. [Bacteriophage H-19B] gi|2668771|gb|AAD04658.1 NP_310289.1 similar to hypothetical protein [Bacteriophage 933W] NP_310292.1 similar to tellurium resistance proteins (TerB) e.g. [Deinococcus radiodurans] gi|7473690|pir||C75302 NP_310294.1 similar to antitermination Q proteins e.g. [Bacteriophage 82] gi|132277|sp|P13870|REGQ_BP82 NP_310295.1 similar to Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1, crossover junction endodeoxyribonucleases Rus; Holliday junction nuclease NP_310296.1 similar to B1560_ECOLI gi|1787843 NP_310300.1 similar to hypothetical protein [Salmonella typhimurium] gi|7467246|pir||T03012, Ren proteins e.g. [Bacteriophage H-19] gi|2668762|gb|AAD04649.1 NP_310302.1 acts to load the DnaB helicase onto the intiation site durning DNA replication NP_310303.1 similar to replication proteins e.g. [Bacteriophage phi-80] gi|137940|sp|P14815|VG15_BPPH8, hypothetical protein [Escherichia coli] gi|3025235|sp|P75978|YMFN_ECOLI NP_310304.1 similar to hypothetical protein YdaY [Escherichia coli K-12] gi|3025103|sp|P76064|YDAT_ECOLI NP_310305.1 similar to hypothetical protein YdaS [Escherichia coli] gi|3025102|sp|P76063|YDAS_ECOLI NP_310306.1 similar to hypothetical protein b1145 [Escherichia coli cryptic prophage e14] gi|7444154|pir||F64859 NP_310308.1 similar to hypothetical protein [Rhizobium sp. NGR234] gi|2496690|sp|P55534|Y4KP_RHISN NP_310311.1 similar to DICB_ECOLI gi|1787857 (conserved in Escherichia coli K-12) NP_310312.1 similar to YDFD_ECOLI gi|1787858 NP_310313.1 similar to YDFE_ECOLI gi|1787859 NP_310314.1 similar to excisionases e.g. [Bacteriophage VT2-Sa] dad|AP000363-2|BAA84285.1 NP_310315.1 similar to B1582_ECOLI gi|1787865 (conserved in Escherichia coli K-12) NP_310316.1 similar to B1583_ECOLI gi|1787866 (conserved in Escherichia coli K-12) NP_310317.1 similar to SPEG_ECOLI gi|1787867 (conserved in Escherichia coli K-12) NP_310318.2 similar to YNFC_ECOLI gi|1787868 (conserved in Escherichia coli K-12) NP_310319.1 similar to B1586_ECOLI gi|1787869 (conserved in Escherichia coli K-12) NP_310320.1 similar to B1587_ECOLI gi|1787870 (conserved in Escherichia coli K-12) NP_310321.1 similar to B1588_ECOLI gi|1787871 (conserved in Escherichia coli K-12) NP_310322.1 similar to DMSB_ECOLI gi|1787122 (conserved in Escherichia coli K-12) NP_310323.1 similar to B1590_ECOLI gi|1787873 (conserved in Escherichia coli K-12) NP_310324.2 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane NP_310325.2 similar to B1592_ECOLI gi|1787876 (conserved in Escherichia coli K-12) NP_310326.2 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium NP_310327.1 similar to MLC_ECOLI gi|1787878 (conserved in Escherichia coli K-12) NP_310328.1 similar to YNFL_ECOLI gi|1787879 (conserved in Escherichia coli K-12) NP_310329.1 similar to YNFM_ECOLI gi|1787880 (conserved in Escherichia coli K-12) NP_310330.2 required for growth and survival under moderately acid conditions NP_310331.1 similar to B1598_ECOLI gi|1787882 (conserved in Escherichia coli K-12) NP_310332.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS NP_310333.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS NP_310334.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes NP_310335.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme NP_310336.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm NP_310337.1 similar to B1604_ECOLI gi|1787889 (conserved in Escherichia coli K-12) NP_310338.1 similar to B1605_ECOLI gi|1787890 (conserved in Escherichia coli K-12) NP_310339.1 similar to YDGB_ECOLI gi|1787891 (conserved in Escherichia coli K-12) NP_310340.1 similar to YDGC_ECOLI gi|1787892 (conserved in Escherichia coli K-12) NP_310341.1 response regulator in two-component regulatory system with RstB NP_310342.1 similar to RSTB_ECOLI gi|1787894 (conserved in Escherichia coli K-12) NP_310343.1 binds to DNA replication terminator sequences to prevent passage of replication forks NP_310344.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_310345.1 similar to FUMA_ECOLI gi|1787897 (conserved in Escherichia coli K-12) NP_310346.1 similar to MANA_ECOLI gi|1787899 (conserved in Escherichia coli K-12) NP_310347.1 similar to YDGA_ECOLI gi|1787900 (conserved in Escherichia coli K-12) NP_310350.1 similar to UIDB_ECOLI gi|1787902 (conserved in Escherichia coli K-12) NP_310353.1 similar to UIDR_ECOLI gi|1787904 (conserved in Escherichia coli K-12) NP_310354.1 Acts on the hydroxyl group at position 7 of the steroid frame NP_310355.1 regulates malXY which are involved in maltose-glucose transport NP_310356.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site NP_310357.1 similar to MALY_ECOLI gi|1787909 (conserved in Escherichia coli K-12) NP_310358.1 catalyzes the formation of inosine from adenosine NP_310359.2 similar to B1624_ECOLI gi|1787911 (conserved in Escherichia coli K-12) NP_310360.1 similar to BLR_ECOLI gi|8953941 (conserved in Escherichia coli K-12) NP_310361.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes NP_310362.1 similar to B1626_ECOLI gi|1787913 (conserved in Escherichia coli K-12) NP_310363.1 similar to B1627_ECOLI gi|1787914 (conserved in Escherichia coli K-12) NP_310364.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen NP_310365.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen NP_310366.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents NP_310367.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen NP_310368.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase NP_310369.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines NP_310370.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation NP_310371.1 similar to GST_ECOLI gi|1787923 (conserved in Escherichia coli K-12) NP_310372.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal NP_310373.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_310374.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate NP_310375.2 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme NP_310376.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling NP_310377.1 similar to SLYB_ECOLI gi|1787929 (conserved in Escherichia coli K-12) NP_310378.2 Transcription regulator that can both activate or repress expression NP_310379.1 similar to B1643_ECOLI gi|1787931 (conserved in Escherichia coli K-12) NP_310380.2 similar to B1644_ECOLI gi|1787932 (conserved in Escherichia coli K-12) NP_310381.1 similar to B1645_ECOLI gi|1787933 (conserved in Escherichia coli K-12) NP_310382.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water NP_310383.1 similar to B1647_ECOLI gi|1787936 NP_310384.1 similar to B1648_ECOLI gi|1787937 (conserved in Escherichia coli K-12) NP_310385.1 similar to B1649_ECOLI gi|1787938 (conserved in Escherichia coli K-12) NP_310386.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide NP_310387.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione NP_310388.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) NP_310389.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli NP_310390.1 similar to YDHD_ECOLI gi|1787943 (conserved in Escherichia coli K-12) NP_310391.1 similar to YDHO_ECOLI gi|1787944 (conserved in Escherichia coli K-12) NP_310392.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals NP_310393.1 similar to B1657_ECOLI gi|1787947 (conserved in Escherichia coli K-12) NP_310394.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers NP_310395.1 similar to YDHB_ECOLI gi|1787949 (conserved in Escherichia coli K-12) NP_310396.1 uncharacterized member of the major facilitator superfamily (MFS) NP_310397.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge NP_310398.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_310399.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones NP_310400.1 similar to B1664_ECOLI gi|1787954 (conserved in Escherichia coli K-12) NP_310401.1 similar to B1667_ECOLI gi|1787956 (conserved in Escherichia coli K-12) NP_310402.1 similar to B1668_ECOLI gi|1787957 (conserved in Escherichia coli K-12) NP_310403.1 similar to B1669_ECOLI gi|1787958 (conserved in Escherichia coli K-12) NP_310404.1 similar to YDHU_ECOLI gi|1787959 (conserved in Escherichia coli K-12) NP_310405.1 similar to B1671_ECOLI gi|1787960 (conserved in Escherichia coli K-12) NP_310406.1 similar to B1672_ECOLI gi|1787961 (conserved in Escherichia coli K-12) NP_310407.1 similar to B1673_ECOLI gi|1787962 (conserved in Escherichia coli K-12) NP_310408.1 similar to B1674_ECOLI gi|1787963 (conserved in Escherichia coli K-12) NP_310409.1 similar to B1675_ECOLI gi|1787964 (conserved in Escherichia coli K-12) NP_310410.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_310411.1 similar to LPP_ECOLI gi|1787967 (conserved in Escherichia coli K-12) NP_310412.1 similar to YNHG_ECOLI gi|1787968 (conserved in Escherichia coli K-12) NP_310413.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine NP_310414.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine NP_310415.1 with SufBC activates cysteine desulfurase SufS NP_310416.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE NP_310417.2 with SufCD activates cysteine desulfurase SufS NP_310418.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein NP_310419.1 similar to B1685_ECOLI gi|1787975 (conserved in Escherichia coli K-12) NP_310420.1 similar to B1686_ECOLI gi|1787976 (conserved in Escherichia coli K-12) NP_310421.1 similar to YDIJ_ECOLI gi|1787977 (conserved in Escherichia coli K-12) NP_310422.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function NP_310423.1 similar to B1689_ECOLI gi|1787980 (conserved in Escherichia coli K-12) NP_310424.1 similar to B1690_ECOLI gi|1787981 (conserved in Escherichia coli K-12) NP_310425.1 similar to B1691_ECOLI gi|1787982 (conserved in Escherichia coli K-12) NP_310426.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate NP_310427.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis NP_310428.1 similar to YDIF_ECOLI gi|1787985 (conserved in Escherichia coli K-12) NP_310429.2 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain NP_310430.1 similar to B1696_ECOLI gi|1787987 (conserved in Escherichia coli K-12) NP_310431.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain NP_310432.1 May play a role in a redox process NP_310433.1 similar to YDIS_ECOLI gi|1787991 (conserved in Escherichia coli K-12) NP_310434.1 similar to YDIT_ECOLI gi|1787992 (conserved in Escherichia coli K-12) NP_310435.2 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids NP_310436.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_310437.1 similar to YDIA_ECOLI gi|1787995 (conserved in Escherichia coli K-12) NP_310438.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate NP_310439.1 similar to YDIE_ECOLI gi|1787998 (conserved in Escherichia coli K-12) NP_310440.1 similar to B1706_ECOLI gi|1787999 (conserved in Escherichia coli K-12) NP_310441.1 similar to B1707_ECOLI gi|1788000 (conserved in Escherichia coli K-12) NP_310442.1 similar to NLPC_ECOLI gi|1788001 (conserved in Escherichia coli K-12) NP_310443.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell NP_310444.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane NP_310445.1 with BtuD and BtuF transports vitamin B12 into the cell NP_310446.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control NP_310447.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_310448.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_310450.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_310451.3 similar to RPMI_ECOLI gi|1788010 (conserved in Escherichia coli K-12) NP_310452.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_310453.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_310454.1 similar to B1720_ECOLI gi|1788014, 1721_ECOLI gi|1788015 NP_310455.1 similar to B1722_ECOLI gi|1788016 (conserved in Escherichia coli K-12) NP_310456.2 similar to PFKB_ECOLI gi|1788017 (conserved in Escherichia coli K-12) NP_310457.1 similar to B1724_ECOLI gi|1788018 (conserved in Escherichia coli K-12) NP_310458.1 similar to B1725_ECOLI gi|1788019 (conserved in Escherichia coli K-12) NP_310459.1 similar to B1726_ECOLI gi|1788020 (conserved in Escherichia coli K-12) NP_310460.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate NP_310461.2 similar to B1728_ECOLI gi|1788023 (conserved in Escherichia coli K-12) NP_310462.1 similar to B1729_ECOLI gi|1788024 (conserved in Escherichia coli K-12) NP_310463.2 similar to B1730_ECOLI gi|1788025 (conserved in Escherichia coli K-12) NP_310464.1 similar to B1731_ECOLI gi|1788026 (conserved in Escherichia coli K-12) NP_310465.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide NP_310466.1 similar to YDJC_ECOLI gi|1788028 (conserved in Escherichia coli K-12) NP_310467.1 similar to CELF_ECOLI gi|1788029 (conserved in Escherichia coli K-12) NP_310468.1 represses the celABCDF-ydjC operon involved in carbon uptake NP_310469.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake NP_310470.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake NP_310471.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake NP_310472.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein NP_310473.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers NP_310474.1 3' incision activity; acts with UvrC NP_310475.1 similar to B1742_ECOLI gi|1788038 (conserved in Escherichia coli K-12) NP_310476.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP NP_310477.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism NP_310478.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation NP_310479.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH NP_310480.1 similar to B1747_ECOLI gi|1788043 (conserved in Escherichia coli K-12) NP_310481.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate NP_310482.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction NP_310483.2 similar to YDJX_ECOLI gi|1788047 (conserved in Escherichia coli K-12) NP_310484.2 similar to YDJY_ECOLI gi|1788048 (conserved in Escherichia coli K-12) NP_310485.1 similar to YDJZ_ECOLI gi|1788049 (conserved in Escherichia coli K-12) NP_310486.1 similar to YNJA_ECOLI gi|1788050 (conserved in Escherichia coli K-12) NP_310487.1 similar to B1754_ECOLI gi|1788051 (conserved in Escherichia coli K-12) NP_310488.2 similar to B1755_ECOLI gi|1788052 (conserved in Escherichia coli K-12) NP_310489.1 similar to B1756_ECOLI gi|1788053 (conserved in Escherichia coli K-12) NP_310490.2 similar to B1757_ECOLI gi|1788054 (conserved in Escherichia coli K-12) NP_310491.1 similar to B1758_ECOLI gi|1788055 (conserved in Escherichia coli K-12) NP_310492.1 similar to B1759_ECOLI gi|1788056 (conserved in Escherichia coli K-12) NP_310493.1 similar to B1760_ECOLI gi|1788057 (conserved in Escherichia coli K-12) NP_310494.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer NP_310495.1 similar to B1762_ECOLI gi|1788060 NP_310496.1 decatenates replicating daughter chromosomes NP_310497.1 catalyzes the formation of selenophosphate from selenide and ATP NP_310498.1 similar to YDJA_ECOLI gi|1788063 (conserved in Escherichia coli K-12) NP_310499.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane NP_310500.2 similar to hypothetical proteins e.g. CJ0034c [Campylobacter jejuni] gi|6967539|emb|CAB72527.1 NP_310501.1 converts asparagine to aspartate and ammonia NP_310502.2 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide NP_310503.1 similar to YDJE_ECOLI gi|1788068 NP_310504.1 OrfA protein of insertion sequence IS629; similar to hypothetical proteins e.g. TnpE [Shigella flexneri] gi|5532454|gb|AAD44738.1|AF141323_9 NP_310505.1 OrfB protein of insertion sequence IS629; similar to transposase of IS629 gi|7443863|pir||T00315 NP_310506.1 similar to B1770_ECOLI gi|1788069 (conserved in Escherichia coli K-12) NP_310507.1 similar to B1771_ECOLI gi|1788070 (conserved in Escherichia coli K-12) NP_310508.1 similar to B1772_ECOLI gi|1788071 (conserved in Escherichia coli K-12) NP_310509.1 similar to B1773_ECOLI gi|1788072 (conserved in Escherichia coli K-12) NP_310510.1 similar to YDJJ_ECOLI gi|1788073 (conserved in Escherichia coli K-12) NP_310511.1 similar to B1775_ECOLI gi|1788074 (conserved in Escherichia coli K-12) NP_310512.1 similar to B1776_ECOLI gi|1788075 (conserved in Escherichia coli K-12) NP_310513.2 similar to B1777_ECOLI gi|1788076 (conserved in Escherichia coli K-12) NP_310514.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress NP_310515.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_310516.2 similar to YEAD_ECOLI gi|1788080 (conserved in Escherichia coli K-12) NP_310517.1 similar to B1781_ECOLI gi|1788081 (conserved in Escherichia coli K-12) NP_310518.1 similar to MIPA_ECOLI gi|1788082 (conserved in Escherichia coli K-12) NP_310519.1 similar to YEAG_ECOLI gi|1788083 (conserved in Escherichia coli K-12) NP_310520.1 similar to YEAH_ECOLI gi|1788084 (conserved in Escherichia coli K-12) NP_310521.1 similar to YEAI_ECOLI gi|1788085 (conserved in Escherichia coli K-12) NP_310522.2 similar to YEAJ_ECOLI gi|1788086 (conserved in Escherichia coli K-12) NP_310523.1 similar to YEAK_ECOLI gi|1788087 (conserved in Escherichia coli K-12) NP_310524.1 similar to B1788_ECOLI gi|1788088 (conserved in Escherichia coli K-12) NP_310525.1 similar to YEAL_ECOLI gi|1788090 (conserved in Escherichia coli K-12) NP_310526.1 similar to YEAM_ECOLI gi|1788091 (conserved in Escherichia coli K-12) NP_310527.1 similar to YEAN_ECOLI gi|1788092 (conserved in Escherichia coli K-12) NP_310528.2 similar to YEAO_ECOLI gi|1788093 (conserved in Escherichia coli K-12) NP_310529.1 similar to YOAF_ECOLI gi|1788094 (conserved in Escherichia coli K-12) NP_310530.1 similar to YAEP_ECOLI gi|1788095 (conserved in Escherichia coli K-12) NP_310531.1 similar to YEAQ_ECOLI gi|1788096 (conserved in Escherichia coli K-12) NP_310532.1 similar to YOAG_ECOLI gi|1788097 (conserved in Escherichia coli K-12) NP_310533.1 similar to YEAR_ECOLI gi|1788098 (conserved in Escherichia coli K-12) NP_310534.1 similar to YEAS_ECOLI gi|1788099 (conserved in Escherichia coli K-12) NP_310535.2 similar to YEAT_ECOLI gi|1788100 (conserved in Escherichia coli K-12) NP_310536.1 similar to YEAU_ECOLI gi|1788101 (conserved in Escherichia coli K-12) NP_310537.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function NP_310538.1 similar to YEAW_ECOLI gi|1788103 (conserved in Escherichia coli K-12) NP_310539.1 similar to YEAX_ECOLI gi|1788104 (conserved in Escherichia coli K-12) NP_310540.1 similar to RND_ECOLI gi|1788105 (conserved in Escherichia coli K-12) NP_310541.1 Activates fatty acids by binding to coenzyme A NP_310542.1 similar to B1806_ECOLI gi|1788108 (conserved in Escherichia coli K-12) NP_310543.1 similar to YEAZ_ECOLI gi|1788109 (conserved in Escherichia coli K-12) NP_310544.1 similar to B1808_ECOLI gi|1788110 (conserved in Escherichia coli K-12) NP_310545.1 similar to B1809_ECOLI gi|1788111 (conserved in Escherichia coli K-12) NP_310546.1 similar to B1810_ECOLI gi|1788112 (conserved in Escherichia coli K-12) NP_310547.1 similar to B1811_ECOLI gi|1788113 (conserved in Escherichia coli K-12) NP_310548.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine NP_310549.1 similar to YEAB_ECOLI gi|1788115 (conserved in Escherichia coli K-12) NP_310550.1 similar to SDAA_ECOLI gi|1788116 (conserved in Escherichia coli K-12) NP_310551.1 similar to B1815_ECOLI gi|1788118 (conserved in Escherichia coli K-12) NP_310552.1 similar to YOAE_ECOLI gi|1788119 (conserved in Escherichia coli K-12) NP_310554.1 similar to MANX_ECOLI gi|1788120 (conserved in Escherichia coli K-12) NP_310555.1 similar to MANY_ECOLI gi|1788121 (conserved in Escherichia coli K-12) NP_310556.3 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel NP_310557.1 similar to B1820_ECOLI gi|1788123 (conserved in Escherichia coli K-12) NP_310558.1 membrane protein YebN NP_310559.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth NP_310560.1 similar to CSPC_ECOLI gi|1788126 (conserved in Escherichia coli K-12) NP_310561.1 similar to B1824_ECOLI gi|1788127 (conserved in Escherichia coli K-12) NP_310562.1 similar to B1825_ECOLI gi|1788128 (conserved in Escherichia coli K-12) NP_310563.1 similar to B1826_ECOLI gi|1788130 (conserved in Escherichia coli K-12) NP_310564.1 similar to B1827_ECOLI gi|1788131 (conserved in Escherichia coli K-12) NP_310565.2 similar to B1828_ECOLI gi|1788132 (conserved in Escherichia coli K-12) NP_310566.1 metalloprotease NP_310567.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 NP_310568.1 affects solute and DNA transport through an unknown mechanism NP_310569.2 similar to B1832_ECOLI gi|1788136 (conserved in Escherichia coli K-12) NP_310570.1 similar to B1833_ECOLI gi|1788137 (conserved in Escherichia coli K-12) NP_310571.1 similar to B1834_ECOLI gi|1788138 (conserved in Escherichia coli K-12) NP_310572.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA NP_310573.1 similar to B1836_ECOLI gi|1788141 (conserved in Escherichia coli K-12) NP_310574.1 similar to B1837_ECOLI gi|1788142 (conserved in Escherichia coli K-12) NP_310575.2 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins NP_310576.1 similar to B1839_ECOLI gi|1788144 (conserved in Escherichia coli K-12) NP_310577.1 similar to B1840_ECOLI gi|1788145 (conserved in Escherichia coli K-12) NP_310578.1 similar to B1841_ECOLI gi|1788146 (conserved in Escherichia coli K-12) NP_310579.1 similar to HOLE_ECOLI gi|1788147 (conserved in Escherichia coli K-12) NP_310580.1 similar to B1843_ECOLI gi|1788148 (conserved in Escherichia coli K-12) NP_310581.1 3'-5' exonuclease activity on single or double-strand DNA NP_310582.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues NP_310583.1 similar to YEBE_ECOLI gi|1788151 (conserved in Escherichia coli K-12) NP_310584.1 secreted protein; unknown function NP_310585.1 similar to YEBG_ECOLI gi|1788153 (conserved in Escherichia coli K-12) NP_310586.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis NP_310587.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate NP_310588.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate NP_310589.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_310590.1 Represses the expression of the zwf, eda, glp and gap NP_310591.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_310592.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA NP_310593.2 similar to YEBA_ECOLI gi|1788162 (conserved in Escherichia coli K-12) NP_310594.3 involved in transport of zinc(II) with ZnuA and C NP_310595.1 involved in transport of zinc(II) with ZnuA and C NP_310596.1 involved in transport of zinc(II) with ZnuA and C NP_310597.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_310598.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_310599.2 similar to YEBB_ECOLI gi|1788169 (conserved in Escherichia coli K-12) NP_310600.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_310601.1 similar to YEBC_ECOLI gi|1788171 (conserved in Escherichia coli K-12) NP_310602.1 converts dATP to dAMP and pyrophosphate NP_310603.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_310604.2 similar to YECD_ECOLI gi|1788174 (conserved in Escherichia coli K-12) NP_310605.1 similar to YECE_ECOLI gi|1788175 (conserved in Escherichia coli K-12) NP_310606.2 similar to YECN_ECOLI gi|1788176 (conserved in Escherichia coli K-12) NP_310607.1 similar to YECO_ECOLI gi|1788177 (conserved in Escherichia coli K-12) NP_310608.1 similar to YECP_ECOLI gi|1788178 (conserved in Escherichia coli K-12) NP_310609.2 similar to BISZ_ECOLI gi|1788180 (conserved in Escherichia coli K-12) NP_310610.1 similar to YECK_ECOLI gi|1788181 (conserved in Escherichia coli K-12) NP_310611.2 similar to CUTC_ECOLI gi|1788182 (conserved in Escherichia coli K-12) NP_310612.2 similar to YECM_ECOLI gi|1788183 (conserved in Escherichia coli K-12) NP_310613.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_310614.1 similar to YECT_ECOLI gi|1788185 (conserved in Escherichia coli K-12) NP_310615.1 similar to FLHE_ECOLI gi|1788186 (conserved in Escherichia coli K-12) NP_310616.1 membrane protein involved in the flagellar export apparatus NP_310617.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export NP_310618.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation NP_310619.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble NP_310620.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins NP_310621.1 methylates the MCP NP_310622.1 mediates taxis toward dipeptides NP_310623.1 similar to TAR_ECOLI gi|1788195 (conserved in Escherichia coli K-12) NP_310624.1 similar to CHEW_ECOLI gi|1788196 (conserved in Escherichia coli K-12) NP_310625.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component NP_310626.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_310627.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine NP_310628.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems NP_310629.2 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems NP_310630.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress NP_310631.1 similar to OTSA_ECOLI gi|1788206 (conserved in Escherichia coli K-12) NP_310632.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature NP_310635.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose NP_310636.1 similar to ARAF_ECOLI gi|1788211 (conserved in Escherichia coli K-12) NP_310637.1 similar to YECI_ECOLI gi|1788212 (conserved in Escherichia coli K-12) NP_310639.1 similar to B1904_ECOLI gi|1788215 (conserved in Escherichia coli K-12) NP_310640.1 cytoplasmic iron storage protein NP_310641.1 similar to YECH_ECOLI gi|1788217 (conserved in Escherichia coli K-12) NP_310642.1 similar to TYRP_ECOLI gi|1788218 (conserved in Escherichia coli K-12) NP_310643.1 similar to YECA_ECOLI gi|1788219 (conserved in Escherichia coli K-12) NP_310644.1 similar to integrases e.g. [Bacteriophage S2] gi|1679807|emb|CAA96221.1 NP_310645.1 similar to hypothetical protein b1839 [Escherichia coli] gi|7451973|pir||G64945 NP_310646.1 similar to cell division protein Div [Escherichia coli] gi|2494741|sp|Q11185|YPD5_CAEEL NP_310647.1 similar to transcriptional regulators e.g. [Neisseria meningitidis] gi|7226247|gb|AAF41408.1 NP_310649.1 similar to DNA-binding protein Cox [Vibrio cholerae Bacteriophage K139] gi|4530499|gb|AAD22064.1, phage hypothetical proteins e.g. [Bacteriophage S2] gi|1679810| NP_310658.1 similar to derepression protein epsilon [Bacteriophage P4] gi|137833|sp|P05463|VEPS_BPP4 NP_310660.1 similar to replication proteins e.g. GpA [Bacteriophage 186] gi|1351406|sp|P41064|VPA_BP186 NP_310661.1 similar to plasmid partition proteins e.g. par [Escherichia coli plasmid R1] gi|134954|sp|P11904|STBA_ECOLI NP_310662.1 similar to plasmid partition proteins e.g. TSB [Escherichia coli plasmid NR1] gi|134956|sp|P11906|STBB_ECOLI NP_310663.1 OrfB protein of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_310664.1 OrfA protein of insertion sequence IS629; similar to hypothetical proteins in insertion sequences e.g. [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_310665.1 similar to hypothetical proteins e.g. orf20 [Escherichia coli plasmid pB171] gi|6009396|dbj|BAA84855.1 NP_310666.2 similar to tail proteins e.g. F protein [Bacteriophage 186] gi|3337273|gb|AAC34171.1 NP_310669.1 similar to gi|3139111|gb|AAD03292.1 NP_310670.1 similar to tail protein e.g. GpE [Bacteriophage P2] gi|3139110|gb|AAD03291.1 NP_310671.1 similar to tail tube proteins e.g. tail protein FII [Bacteriophage 186] gi|139325|sp|P22502|VPF2_BPP2 NP_310672.1 similar to tail sheath proteins e.g. FI [Pseudomonas aeruginosa bacteriophage phiCTX] gi|4063795|dbj|BAA36249.1 NP_310673.1 similar to tail proteins e.g. GpD [Bacteriophage P2] gi|6136287|sp|P10312|VPD_BPP2 NP_310677.1 similar to PGSA_ECOLI gi|1788220 (conserved in Escherichia coli K-12) NP_310678.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_310679.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system NP_310680.1 similar to YECF_ECOLI gi|1788223 (conserved in Escherichia coli K-12) NP_310681.1 regulates genes involved in cell division NP_310682.1 similar to YECC_ECOLI gi|1788225 (conserved in Escherichia coli K-12) NP_310683.1 similar to YECS_ECOLI gi|1788226 (conserved in Escherichia coli K-12) NP_310686.1 similar to FLIY_ECOLI gi|1788228 (conserved in Escherichia coli K-12) NP_310687.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence NP_310688.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes NP_310689.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes NP_310690.1 involved in flagellin assembly NP_310691.1 flagellin specific chaperone NP_310692.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family NP_310693.1 converts 1,4-alpha-D-glucans to maltodextrin NP_310694.2 similar to YEDD_ECOLI gi|1788237 (conserved in Escherichia coli K-12) NP_310695.1 similar to YEDE_ECOLI gi|1788238 (conserved in Escherichia coli K-12) NP_310696.1 similar to YEDF_ECOLI gi|1788239 (conserved in Escherichia coli K-12) NP_310697.1 similar to YEDK_ECOLI gi|1788240 (conserved in Escherichia coli K-12) NP_310702.1 similar to B1936_ECOLI gi|1788246 (conserved in Escherichia coli K-12) NP_310703.1 forms a junction between the M-ring and FlgB during flagella biosynthesis NP_310704.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod NP_310705.1 One of three proteins involved in switching the direction of the flagellar rotation NP_310706.2 binds to and inhibits the function of flagella specific ATPase FliI NP_310707.1 involved in type III protein export during flagellum assembly NP_310708.1 rod/hook and filament chaperone NP_310709.1 similar to FLIK_ECOLI gi|1788253 (conserved in Escherichia coli K-12) NP_310710.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring NP_310711.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation NP_310712.1 One of three proteins involved in switching the direction of the flagellar rotation NP_310713.2 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus NP_310714.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus NP_310715.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus NP_310716.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus NP_310717.1 similar to RCSA_ECOLI gi|1788262 (conserved in Escherichia coli K-12) NP_310718.1 similar to DSRB_ECOLI gi|1788263 (conserved in Escherichia coli K-12) NP_310719.2 similar to B1953_ECOLI gi|1788264 (conserved in Escherichia coli K-12) NP_310720.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate NP_310721.1 similar to B1956_ECOLI gi|1788266 (conserved in Escherichia coli K-12) NP_310722.1 similar to B1957_ECOLI gi|1788267 (conserved in Escherichia coli K-12) NP_310723.1 similar to YEDI_ECOLI gi|1788268 (conserved in Escherichia coli K-12) NP_310724.1 similar to YEDA_ECOLI gi|1788269 (conserved in Escherichia coli K-12) NP_310725.1 similar to VSR_ECOLI gi|1788270 (conserved in Escherichia coli K-12); Vsr NP_310726.1 similar to DCM_ECOLI gi|1788271 (conserved in Escherichia coli K-12) NP_310727.1 similar to YEDJ_ECOLI gi|1788273 (conserved in Escherichia coli K-12) NP_310728.1 similar to B1963_ECOLI gi|1788274 (conserved in Escherichia coli K-12) NP_310729.1 similar to B1964_ECOLI gi|1788275, B1965_ECOLI gi|1788276, OMPC_ECOLI gi|1788544 NP_310730.1 similar to B1965_ECOLI gi|1788276, outer membrane protein B1966_ECOLI gi|1788277 NP_310732.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress NP_310733.1 similar to YEDV_ECOLI gi|1788279 (conserved in Escherichia coli K-12) NP_310734.2 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced NP_310735.1 similar to B1970_ECOLI gi|1788281 (conserved in Escherichia coli K-12) NP_310736.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ NP_310737.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme NP_310738.1 similar to B1973_ECOLI gi|1788284 (conserved in Escherichia coli K-12) NP_310739.1 similar to YODB_ECOLI gi|1788286 (conserved in Escherichia coli K-12) NP_310742.1 secerted effector protein; similar to hypothetical proteins e.g. EspF [Escherichia coli strain B10] gi|6090818|gb|AAF03351.1|AF116900_2 ESPF_ECOLI NP_310743.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_310744.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_310745.1 similar to Lom outer membrane protein precursors e.g. [prophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2 NP_310748.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_310749.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_310750.1 similar to minor tail proteins e.g. GpL [Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_310751.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_310754.1 bacteriophage tail component; similar to minor tail proteins e.g. GpT [Bacteriophage lambda] gi|138846|sp|P03735|VMTT_LAMBD; may be produced by translational frameshift NP_310755.1 bacteriophage tail component; similar to minor tail proteins e.g. GpG [Bacteriophage lambda]gi|138842|sp|P03734|VMTG_LAMBD NP_310757.1 bacteriophage head component; may be truncated; similar to major head proteins e.g. Gp7 [Bacteriophage 21] gi|547612|sp|P36270|HEAD_BPP21, gi|547612|sp|P36270 NP_310758.1 bacteriophage head component; similar to head decoration proteins e.g. Gpshp [Bacteriophage 21] gi|549437|sp|P36275|VSHP_BPP21 NP_310759.1 similar to minor head proteins e.g. head-tail preconnector Gp5 [Bacteriophage 21] gi|549296|sp|P36273|VG05_BPP21; contains scaffold protein NP_310760.1 similar to portal proteins e.g. Gp5 [Bacteriophage 21] gi|549295|sp|P36272|VG04_BPP21 NP_310761.1 similar to phage proteins e.g. head completion protein Gp3 [Bacteriophage 21] gi|549294|sp|P36271|VG03_BPP21 NP_310762.1 similar to terminase large subunits e.g. Gp2 [Bacteriophage 21] gi|2851579|sp|P36693|TERL_BPP21 NP_310763.1 similar to terminase small subunits e.g. Gp1 [Bacteriophage N15] gi|7444578|pir||T13087 NP_310764.1 similar to PerC (BfpW) [Escherichia coli] gi|1172431|sp|P43475|PERC_ECOLI NP_310765.1 host cell lysis; similar to Rz endopeptidases e.g. [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1| NP_310768.1 similar to s e.g. R protein [Bacteriophage H-19B] gi|4335686|gb|AAD17382.1| NP_310769.1 similar to YdfR [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_310770.1 host cell lysis; similar to holins e.g. protein S [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1| NP_310771.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_310772.1 OrfB protein of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_310773.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_310776.1 similar to TerB proteins e.g. [Deinococcus radiodurans] gi|7473690|pir||C75302 NP_310777.1 similar to antiterminators e.g. protein Q [Bacteriophage 82] gi|132277|sp|P13870|REGQ_BP82 NP_310778.1 similar to Rus protein e.g. [Bacteriophage 82] gi|6901639|gb|AAF31142.1| GP67_BPHK97, Gp67 [Bacteriophage HK97] gi|6901639|gb|AAF31142.1| NP_310779.1 similar to hypothetical proteins e.g. b1560 [Escherichia coli] gi|7466196|pir||C64911 NP_310780.1 similar to orf QD1 [Bacteriophage N15] gi|2564084|gb|AAB81659.1| NP_310781.1 similar to Hok/Gef family e.g. MokW [Bacteriophage 933W] gi|4585453|gb|AAD25481.1|AF125520_76 NP_310783.1 similar to GP45 Bacteriophage N15 T13131, Escherichia coli H65009 NP_310788.1 similar to YdaW [Escherichia coli] gi|3025105|sp|P76066|YDAW_ECOLI NP_310789.1 similar to replication proteins e.g. Gp14 [Bacteriophage phi-80] gi|137937|sp|P14814|VG14_BPPH8 NP_310790.1 similar to replication termination factor dnaT (primosomal protein I) [Escherichia coli] gi|1361001|pir||S56589 NP_310791.1 similar to YdaT [Escherichia coli] gi|3025103|sp|P76064|YDAT_ECOLI, regulatory protein CII [Bacteriophage phi-80] gi|133360|sp|P14820|RPC2_BPPH8 NP_310792.1 repressor; similar to DicC (repressor protein of division inhibition gene dicB) [Escherichia coli] gi|118633|sp|P06965|DICC_ECOLI NP_310793.1 similar to repressor proteins e.g. C2 repressor [Bacteriophage P22] gi|133359|sp|P03035|RPC2_BPP22 NP_310795.1 similar to DicB protein [Escherichia coli] gi|2507009|sp|P09557|DICB_ECOLI NP_310796.1 similar to hypothetical proteins e.g. YdfD [Escherichia coli] gi|140587|sp|P29010|YDFD_ECOLI NP_310800.1 similar to integrases e.g. [Bacteriophage HK022] gi|138560|sp|P16407|VINT_BPHK0 NP_310801.2 similar to B1976_ECOLI gi|1788287 (conserved in Escherichia coli K-12) NP_310802.1 similar to B1978_ECOLI gi|1788288; may contain frameshift NP_310803.1 similar to B1978_ECOLI gi|1788288; may contain frameshift NP_310804.1 similar to B1980_ECOLI gi|1788291, B1979_ECOLI gi|1788290 NP_310805.1 similar to SHIA_ECOLI gi|1788292 (conserved in Escherichia coli K-12) NP_310806.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile NP_310807.1 similar to B1983_ECOLI gi|1788294 (conserved in Escherichia coli K-12) NP_310810.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB NP_310811.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation NP_310812.1 similar to ERFK_ECOLI gi|1788299 (conserved in Escherichia coli K-12) NP_310813.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole NP_310814.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole NP_310815.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP NP_310816.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli O157:H7 strain EDL933] gi|3414881|gb|AAC31492.1| NP_310817.1 similar to hypothetical proteins e.g. L0014 [Escherichia coli O157:H7 strain EDL933] gi|3288157|emb|CAA11510.1| NP_310818.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1| NP_310819.1 similar to B1995_ECOLI gi|1788304 NP_310821.1 OrfA protein of insertion sequence IS629; similar to IS629 hypothetical proteins e.g. [Escherichia coli plasmid pO157] gi|7444868|pir||T00241 NP_310822.1 OrfB protein of insertion sequence IS629; similar to IS629 transposase [Escherichia coli plasmid pO157) gi|7443862|pir||T00240 NP_310823.1 similar to hypothetical proteins e.g. YjdA [Escherichia coli] gi|731985|sp|P16694|YJDA_ECOLI NP_310824.1 similar to hypothetical protein YjcZ [Escherichia coli] gi|731984|sp|P39267|YJCZ_ECOLI NP_310825.1 similar to hypothetical protein [Xanthomonas campestris] gi|6689533|emb|CAB65709.1| NP_310828.1 similar to hypothetical proteins e.g. YafZ [Escherichia coli] gi|2495487|sp|P77206|YAFZ_ECOLI NP_310829.1 similar to hypothetical proteins e.g. YfjX [Escherichia coli] gi|1723636|sp|P52139|YFJX_ECOLI, antirestriction proteins e.g. KlcA protein [plasmid RK2] gi|1730051|sp|P52603 NP_310830.1 similar to RADC family DNA repair protein YEES_ECOLI gi|1788312 (conserved in Escherichia coli K-12) NP_310831.1 similar to YEET_ECOLI gi|1788313 (conserved in Escherichia coli K-12) NP_310832.1 similar to YEEU_ECOLI gi|1788314 (conserved in Escherichia coli K-12) NP_310833.1 similar to YEEV_ECOLI gi|1788315 NP_310834.1 similar to YEEW_ECOLI gi|1788316 (conserved in Escherichia coli K-12) NP_310835.1 similar to PduV [Salmonella enterica serovar Typhimurium] gb|AAD39020.1 NP_310836.2 similar to YEEX_ECOLI gi|1788317 (conserved in Escherichia coli K-12) NP_310837.1 similar to YEEA_ECOLI gi|1788318 (conserved in Escherichia coli K-12) NP_310838.1 similar to SBMC_ECOLI gi|1788319 (conserved in Escherichia coli K-12) NP_310839.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains NP_310840.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates NP_310841.1 similar YEED_ECOLI to gi|1788322 (conserved in Escherichia coli K-12) NP_310842.1 similar to YEEE_ECOLI gi|1788323 (conserved in Escherichia coli K-12) NP_310843.1 similar to YEEF_ECOLI gi|1788325 (conserved in Escherichia coli K-12) NP_310844.2 similar to YEEY_ECOLI gi|1788326 (conserved in Escherichia coli K-12) NP_310845.1 similar to B2016_ECOLI gi|1788327 (conserved in Escherichia coli K-12) NP_310847.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors NP_310848.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer NP_310849.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis NP_310850.2 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate NP_310851.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide NP_310852.2 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide NP_310853.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase NP_310854.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis NP_310855.2 similar to WZZB_ECOLI gi|1788339 (conserved in Escherichia coli K-12) NP_310856.1 similar to UGD_ECOLI gi|1788340 (conserved in Escherichia coli K-12) NP_310857.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_310858.1 similar to WbdR [Escherichia coli O157:H7 C664-1992] gi|3435182|gb|AAC32350.1| NP_310860.1 similar to H repeat-associated proteins e.g. [Escherichia coli] gi|140772|sp|P28912|YHHI_ECOLI NP_310862.1 similar to ManB [Escherichia coli O157:H7 C664-1992] gi|3435181|gb|AAC32349.1| NP_310863.1 similar to ManC [Escherichia coli O157:H7 C664-1992] gi|3435180|gb|AAC32348.1| NP_310864.1 similar to WbdQ [Escherichia coli O157:H7 C664-1992] gi|3435179|gb|AAC32347.1| NP_310865.1 similar to Fcl [Escherichia coli O157:H7 C664-1992] gi|4867922|dbj|BAA77731.1| NP_310866.1 similar to Gmd [Escherichia coli O157:H7 C664-1992]gi|3435177|gb|AAC32345.1| NP_310867.1 similar to WbdP [Escherichia coli O157:H7 C664-1992] gi|3435176|gb|AAC32344.1| NP_310868.1 similar to Per [Escherichia coli O157:H7 C664-1992] gi|3435175|gb|AAC32343.1| NP_310869.1 similar to Wzx [Escherichia coli O157:H7 C664-1992] gi|3435174|gb|AAC32342.1| NP_310870.1 similar to WbdO [Escherichia coli O157:H7 C664-1992] gi|3435173|gb|AAC32341.1| NP_310871.1 similar to Wzy [Escherichia coli O157:H7 C664-1992] gi|3435172|gb|AAC32340.1| NP_310872.1 similar to WbdN [Escherichia coli O157:H7 C664-1992] gi|4867915|dbj|BAA77724.1| NP_310873.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose NP_310874.1 similar to probable UDP-galactose 4-epimerase [Vibrio cholerae] gi|3724321|dbj|BAA33610.1 NP_310875.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid NP_310876.1 similar to WCAL_ECOLI gi|1788357 (conserved in Escherichia coli K-12) NP_310877.1 similar to WCAK_ECOLI gi|1788358 (conserved in Escherichia coli K-12) NP_310878.1 similar to WZXC_ECOLI gi|1788359 (conserved in Escherichia coli K-12) NP_310879.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid NP_310880.1 similar to CPSG_ECOLI gi|1788361 (conserved in Escherichia coli K-12) NP_310881.1 similar to CPSB_ECOLI gi|1788362 (conserved in Escherichia coli K-12) NP_310882.1 similar to WCAI_ECOLI gi|1788363 (conserved in Escherichia coli K-12) NP_310883.1 similar to WCAH_ECOLI gi|1788364 (conserved in Escherichia coli K-12) NP_310884.1 similar to WCAG_ECOLI pdb|1GFS_A (conserved in Escherichia coli K-12) NP_310885.1 similar to GMD_ECOLI gi|1788366 (conserved in Escherichia coli K-12) NP_310886.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) NP_310887.1 similar to WCAE_ECOLI gi|1788368 (conserved in Escherichia coli K-12) NP_310888.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance NP_310889.1 similar to WCAC_ECOLI gi|1788370 (conserved in Escherichia coli K-12) NP_310890.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium NP_310891.1 similar to WCAA_ECOLI gi|1788372 (conserved in Escherichia coli K-12) NP_310892.2 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) NP_310893.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis NP_310894.1 similar to WZA_ECOLI gi|1788376 (conserved in Escherichia coli K-12) NP_310895.2 similar to YEGH_ECOLI gi|1788377 (conserved in Escherichia coli K-12) NP_310896.1 similar to hypothetical proteins e.g. gi|9106618|gb|AAF84382.1|AE003986_12 [Xylella fastidiosa] NP_310897.1 similar to hypothetical protein [Xylella fastidiosa] gb|AAF84486.1|AE003993_5 NP_310898.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs NP_310899.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_310900.2 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor NP_310904.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine NP_310905.2 similar to YEGD_ECOLI gi|1788384 (conserved in Escherichia coli K-12) NP_310906.2 similar to chaperonin B2070_ECOLI gi|1788385 (conserved in Escherichia coli K-12) NP_310907.1 similar to B2072_ECOLI gi|1788387 (conserved in Escherichia coli K-12) NP_310908.1 similar to B2073_ECOLI gi|1788388 (conserved in Escherichia coli K-12) NP_310909.2 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate NP_310910.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate NP_310911.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate NP_310912.1 similar to YEGB_ECOLI gi|1788392 (conserved in Escherichia coli K-12) NP_310913.1 similar to BAES_ECOLI gi|1788393 (conserved in Escherichia coli K-12) NP_310914.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport NP_310915.2 similar to B2080_ECOLI gi|1788396 (conserved in Escherichia coli K-12) NP_310916.1 similar to YEGQ_ECOLI gi|1788397 (conserved in Escherichia coli K-12) NP_310917.1 similar to B2084_ECOLI gi|1788400 NP_310918.1 similar to B2085_ECOLI gi|1788401 (conserved in Escherichia coli K-12) NP_310919.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role NP_310920.1 similar to GATR_ECOLI sp|P36930 gi|1788403 (conserved in Escherichia coli K-12) NP_310921.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate NP_310922.1 similar to GATC_ECOLI gi|1788408 (conserved in Escherichia coli K-12) NP_310923.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_310924.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_310925.1 similar to GATZ_ECOLI gi|1788411 (conserved in Escherichia coli K-12) NP_310926.2 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway NP_310927.2 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate NP_310928.1 similar to YEGT_ECOLI gi|1788415 (conserved in Escherichia coli K-12) NP_310929.1 similar to B2099_ECOLI gi|1788416 (conserved in Escherichia coli K-12) NP_310930.1 similar to B2100_ECOLI gi|1788417 (conserved in Escherichia coli K-12) NP_310931.1 similar to YEGW_ECOLI gi|1788418 (conserved in Escherichia coli K-12) NP_310932.1 similar to YEGX_ECOLI gi|1788419 (conserved in Escherichia coli K-12) NP_310933.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine NP_310934.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP NP_310938.1 similar to YOHL_ECOLI gi|1788422 (conserved in Escherichia coli K-12) NP_310939.1 membrane protein conferring nickel and cobalt resistance NP_310940.2 similar to B2107_ECOLI gi|1788424 (conserved in Escherichia coli K-12) NP_310941.1 similar to YEHA_ECOLI gi|1788426 NP_310942.1 similar to YEHB_ECOLI gi|1788427, ousher protein MrkC [Klebsiella pneumoniae] dad|M55912-4|AAA25095.1 NP_310943.1 similar to YEHC_ECOLI gi|1788428, chaperone MrkB [Klebsiella pneumoniae] dad|M55912-3|AAA25094.1 NP_310944.1 similar to YEHD_ECOLI gi|1788429, AC/I pili protein [Escherichia coli] dad|X76121-1|CAA53727.1 NP_310945.1 similar to YEHE_ECOLI gi1788430 NP_310946.2 similar to MRP_ECOLI gi|1788431 (conserved in Escherichia coli K-12) NP_310947.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_310952.1 similar to YEHI_ECOLI gi|1788436 (conserved in Escherichia coli K-12) NP_310953.1 similar to YEHK_ECOLI gi|465578|sp|P33347 (conserved in Escherichia coli K-12) NP_310954.1 similar to YEHL_ECOLI gi|1788438 (conserved in Escherichia coli K-12) NP_310957.1 similar to YEHP_ECOLI gi|1788440 (conserved in Escherichia coli K-12) NP_310958.1 similar to YEHQ_ECOLI gi|1788441 NP_310959.1 OrfB protein of insertion sequence IS629; similar to gi|7443862|pir||T00240 NP_310960.1 OrfA protein of insertion sequence IS629; similar to gi|7444868|pir||T00241 NP_310961.1 similar to YEHR_ECOLI gi|1788442 (conserved in Escherichia coli K-12) NP_310962.1 similar to YEHS_ECOLI gi|1788443 (conserved in Escherichia coli K-12) NP_310963.2 unknown function; when overproduced it confers drug-resistance NP_310964.1 similar to YEHU_ECOLI gi|1788446 (conserved in Escherichia coli K-12) NP_310967.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_310968.1 similar to tail fiber proteins e.g. [Bacteriophage 933W] gi|4585436|gb|AAD25464.1|AF125520_59 NP_310969.1 similar to Lom precursors e.g. [Bacteriophage P-EibA] gi|7532789|gb|AAF63231.1|AF151091_2 NP_310972.1 similar to tail assembly proteins e.g. GpI [Bacteriophage lambda] gi|139637|sp|P03730|VTAI_LAMBD NP_310973.1 similar to tail assembly proteins e.g. GpK [Bacteriophage lambda] gi|139638|sp|P03729|VTAK_LAMBD NP_310974.1 similar to minor tail proteins e.g. GpI[Bacteriophage lambda] gi|138844|sp|P03738|VMTL_LAMBD NP_310975.1 similar to minor tail proteins e.g. GpM [Bacteriophage lambda] gi|138845|sp|P03737|VMTM_LAMBD NP_310976.1 similar to tail length tape measure protein precursors e.g. GpH [Bacteriophage lambda] gi|138843|sp|P03736|VMTH_LAMBD NP_310977.1 similar to minor tail proteins e.g. GpT [Bacteriophage lambda] gi|138846|sp|P03735|VMTT_LAMBD; may be produced by translational frameshift NP_310978.1 similar to minor tail proteins e.g. GpG [Bacteriophage lambda] gi|138842|sp|P03734|VMTG_LAMBD NP_310980.1 similar to minor tail proteins e.g. GpU [Bacteriophage lambda] gi|138847|sp|P03732|VMTU_LAMBD NP_310981.1 similar to minor tail proteins e.g. GpZ [Bacteriophage lambda] gi|138849|sp|P03731|VMTZ_LAMBD NP_310985.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241 NP_310986.1 OrfB protein of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_310987.1 similar to scaffolding protein [Streptococcus thermophilus bacteriophage DT1] gi|4530143|gb|AAD21883.1, protease/scaffold protein, ClpP proteases e.g. [Bacteriophage D3] gi|5059251|gb|AAD38956.1 NP_310988.1 similar to portal protein-like protein [Wolbachia sp. wKue] gi|6723246|dbj|BAA89642.1, portal proteins e.g. gp4 [phage 21] gi|549295|sp|P36272|VG04_BPP21 NP_310990.1 similar to terminase large subunit-like protein [Wolbachia sp. wKue] gi|6723244|dbj|BAA89640.1, terminase large subunits e.g. GpA [Bacteriophage lambda] gi|137616|sp|P0370 NP_310992.1 host cell lysis; similar to Rz [Bacteriophage VT2-Sa] gi|5881639|dbj|BAA84330.1|, similar to endopeptidases e.g. Rz [Bacteriophage lambda] gi|119368|sp|P00726|ENPP_LAMBD NP_310994.1 similar to antirepressor protein [Bacteriophage 933W] gi|4585423|gb|AAD25451.1|AF125520_46, antirepressor protein Ant [Bacteriophage P22] NP_310995.1 similar to endolysin [Bacteriophage 933W] gi|4585422|gb|AAD25450.1|AF125520_45, similar to endolysins e.g. R protein [Bacteriophage H-19B] gi|4335686|gb|AAD17382.1 NP_310996.1 similar to holin [Bacteriophage 933W] gi|4499808|emb|CAB39307.1|, similar to holins e.g. protein S [Bacteriophage 21] gi|138706|sp|P27360|VLYS_BPP21 NP_310997.1 similar to hypothetical protein [Shigella dysenteriae] gi|6759966|gb|AAF28124.1|AF153317_20 NP_310998.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499806|emb|CAB39305.1| NP_310999.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881634|dbj|BAA84325.1| NP_311000.1 similar to Shiga toxin I subunit B precursor gi|134539|sp|P08027|SLTB_BPH30 NP_311001.1 similar to Shiga toxin I subunit A precursor [Shigella dysenteriae] gi|134537|sp|P10149|SLTA_BPH30 NP_311002.1 similar to antitermination proteins e.g. protein Q [Bacteriophage H-19B] NP_311003.1 similar to hypothetical proteins e.g. Nin 68 [Bacteriophage lambda] gi|1351593|sp|P03771|Y68_LAMBD NP_311004.1 similar to hypothetical proteins e.g. NinG protein [Bacteriophage 21] gi|4539482|emb|CAB39991.1| NP_311005.1 similar to hypothetical proteins e.g., NinF [Bacteriophage P22] gi|512350|emb|CAA55162.1| NP_311007.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881625|dbj|BAA84316.1|, Nin E proteins e.g. [Bacteriophage 21] NP_311008.1 similar to hypothetical protein [Bacteriophage VT2-Sa] gi|5881624|dbj|BAA84315.1|, DNA N-6-adenine-methyltransferase [Bacteriophage T1] NP_311009.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585410|gb|AAD25438.1|AF125520_33, NinB [Bacteriophage 21] gi|4539479|emb|CAB39988.1| NP_311010.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585409|gb|AAD25437.1|AF125520_32 NP_311011.1 similar to hypothetical protein [Bacteriophage 933W] gi|4499788|emb|CAB39287.1| NP_311012.1 similar to Ren proteins e.g. [Bacteriophage lambda] gi|139473|sp|P03761|VREN_LAMBD NP_311013.1 similar to phage replication protein P e.g. [Bacteriophage lambda] gi|139488|sp|P03689|VRPP_LAMBD NP_311014.1 similar to phage replication protein O e.g. [Bacteriophage 933W] gi|4585405|gb|AAD25433.1|AF125520_28 NP_311015.1 similar to regulatory protein CII e.g. [Bacteriophage 933W] gi|4585404|gb|AAD25432.1|AF125520_27 NP_311016.1 similar to probable regulatory proteins e.g. [Bacteriophage VT2-Sa] gi|5881616|dbj|BAA84307.1| NP_311017.1 similar to prophage repressor CI e.g. [Bacteriophage lambda] gi|133353|sp|P03034|RPC1_LAMBD NP_311021.1 transcription anti-termination; similar to transcription anti-termination proteins e.g. protein N [Bacteriophage phi-21] gi|132274|sp|P07243|REGN_BPPH3 NP_311022.1 similar to superinfection exclusion protein B [Bacteriophage P22] gi|585991|sp|P38396|SIEB_BPP22 NP_311023.1 similar to single-stranded DNA binding protein [Bacteriophage 933W], Ea10 (single-stranded DNA binding protein) [Bacteriophage lambda] gi|137630|sp|P03757|VE10_LAMBD NP_311024.1 antitermination; similar to regulatory proteins cIII [Bacteriophage lambda] gi|133366|sp|P03044|RPC3_LAMBD NP_311025.1 host killing; similar to Kil proteins e.g. [Bacteriophage lambda] gi|138622|sp|P03758|VKIL_LAMBD NP_311028.1 recombination protein; similar to Bet protein [Bacteriophage 933W] gi|4585391|gb|AAD25419.1|AF125520_14, Bet protein [Bacteriophage lambda] gi|137511|sp|P03698|VBET_LAMBD NP_311029.1 similar to exonucleases [Bacteriophage 933W] gi|4585390|gb|AAD25418.1|AF125520_13, exonucleases e.g. [Bacteriophage lambda] gi|119702|sp|P03697|EXO_LAMBD NP_311030.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585389|gb|AAD25417.1|AF125520_12, hypothetical protein orf60a [Bacteriophage lambda] gi|508995|gb|AAA96568.1| NP_311031.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585388|gb|AAD25416.1|AF125520_11, orf63 [Bacteriophage lambda] gi|508994|gb|AAA96567.1| NP_311032.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585387|gb|AAD25415.1|AF125520_10, hypothetical protein orf61 [Bacteriophage lambda] NP_311033.1 similar to C4-type zinc finger proteins (TraR family) e.g. gi|7649830|dbj|BAA94108.1 NP_311034.1 similar to hypothetical protein Bacteriophage 933W AAD25483, hypothetical protein Bacteriophage HK022 AAF30379 NP_311036.1 similar to hypothetical protein Bacteriophage 933W AAD25410 NP_311037.1 similar to hypothetical proteins e.g. [Bacteriophage 933W] gi|4585455|gb|AAD25483.1|AF125520_78 NP_311039.1 similar to excisionases e.g. [Bacteriophage 933W] gi|4585379|gb|AAD25407.1|AF125520_2 NP_311040.1 similar to integrases e.g. [Bacteriophage 933W] gi|4585378|gb|AAD25406.1|AF125520_1 NP_311041.1 similar to YEHV_ECOLI gi|1788448 (conserved in Escherichia coli K-12) NP_311042.1 similar to YEHW_ECOLI gi|1788449 (conserved in Escherichia coli K-12) NP_311043.1 similar to YEHX_ECOLI gi|1788450 (conserved in Escherichia coli K-12) NP_311044.1 similar to YEHY_ECOLI gi|1788451 (conserved in Escherichia coli K-12) NP_311045.1 similar to YEHZ_ECOLI gi|1788452 (conserved in Escherichia coli K-12) NP_311046.1 similar to BGLX_ECOLI gi|1788453 (conserved in Escherichia coli K-12) NP_311047.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent NP_311048.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 NP_311049.1 similar to YOHC_ECOLI gi|1788457 (conserved in Escherichia coli K-12) NP_311050.1 similar to YOHD_ECOLI gi|1788458 (conserved in Escherichia coli K-12) NP_311051.1 similar to YOHF_ECOLI gi|1788459 (conserved in Escherichia coli K-12) NP_311052.2 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride NP_311053.1 similar to YOHI_ECOLI gi|1788462 (conserved in Escherichia coli K-12) NP_311054.1 catalyzes the formation of catechol from salicylate NP_311055.1 similar to glutathione-S-transferases e.g. [Pseudomonas sp. U2] gi|3406829|gb|AAC29501.1| NP_311056.1 similar to isomerase e.g. isomerase-decarboxylase homolog [Pseudomonas sp. U2] gi|3406828|gb|AAC29500.1, hypothetical protein Orf2 [Sphingomonas sp. RW5] gi|3550668|emb|CAA12268.1| NP_311057.1 similar to gentisate 1,2-dioxygenases e.g. [Pseudomonas alcaligenes] gi|5733104|gb|AAD49427.1|AF173167_1, [Sphingomonas sp. RW5] gi|3550667|emb|CAA12267.1| NP_311058.1 similar to transport proteins e.g. 4-hydroxybenzoate transporter [Pseudomonas putida] gi|6093655|sp|Q51955|PCAK_PSEPU NP_311059.2 similar to regulatory proteins e.g. galactose binding protein regulator [Azospirillum brasilense] gi|1730232|sp|P52661|GBPR_AZOBR NP_311060.1 similar to YOHJ_ECOLI gi|1788463 (conserved in Escherichia coli K-12) NP_311061.1 similar to YOHK_ECOLI gi|1788464 (conserved in Escherichia coli K-12) NP_311062.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis NP_311063.1 similar to SANA_ECOLI gi|1788466 (conserved in Escherichia coli K-12) NP_311064.1 similar to B2145_ECOLI gi|1788467 (conserved in Escherichia coli K-12) NP_311065.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain NP_311066.2 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines NP_311067.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex NP_311068.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains NP_311069.1 similar to MGLB_ECOLI gi|1788473 (conserved in Escherichia coli K-12) NP_311070.1 negative regulator of the mglBAC operon for galactose utilization NP_311071.1 similar to YEIB_ECOLI gi|1788475 (conserved in Escherichia coli K-12) NP_311072.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer NP_311073.1 similar to YEIG_ECOLI gi|1788477 (conserved in Escherichia coli K-12) NP_311074.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein NP_311075.1 similar to LYSP_ECOLI gi|1788480 (conserved in Escherichia coli K-12) NP_311076.1 similar to YEIE_ECOLI gi|1788481 (conserved in Escherichia coli K-12) NP_311077.1 similar to YEIH_ECOLI gi|1788482 (conserved in Escherichia coli K-12) NP_311078.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues NP_311079.1 similar to YEII_ECOLI gi|1788484 (conserved in Escherichia coli K-12) NP_311080.1 similar to YEIJ_ECOLI gi|1788485 (conserved in Escherichia coli K-12) NP_311081.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively NP_311082.2 activator of nucleoside metabolism NP_311083.1 similar to YEIJ_ECOLI gi|1788485 (conserved in Escherichia coli K-12) NP_311084.1 similar to YEIN_ECOLI gi|1788490 (conserved in Escherichia coli K-12) NP_311085.1 similar to YEIC_ECOLI gi|1788491 (conserved in Escherichia coli K-12) NP_311086.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_311087.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers NP_311088.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr NP_311089.1 similar to SETB_ECOLI gi|465603|sp|P33026 (conserved in Escherichia coli K-12) NP_311090.2 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein NP_311091.1 similar to YEIQ_ECOLI gi|1788497 (conserved in Escherichia coli K-12) NP_311092.1 similar to YEIR_ECOLI gi|1788499 (conserved in Escherichia coli K-12) NP_311093.2 similar to B2174_ECOLI gi|1788500 (conserved in Escherichia coli K-12) NP_311094.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance NP_311095.1 similar to RTN_ECOLI gi|1788502 (conserved in Escherichia coli K-12) NP_311096.2 similar to YEJA_ECOLI gi|1788503 (conserved in Escherichia coli K-12) NP_311097.1 similar to YEJB_ECOLI gi|1788504 (conserved in Escherichia coli K-12) NP_311098.1 similar to YEJE_ECOLI gi|1788505 (conserved in Escherichia coli K-12) NP_311099.1 similar to YEJF_ECOLI gi|1788506 (conserved in Escherichia coli K-12) NP_311100.1 similar to YEJG_ECOLI gi|1788507 (conserved in Escherichia coli K-12) NP_311101.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance NP_311102.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA NP_311103.1 similar to YEJH_ECOLI gi|1788511 (conserved in Escherichia coli K-12) NP_311104.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_311105.1 similar to YEJK_ECOLI gi|465615|sp|P33920 (conserved in Escherichia coli K-12) NP_311106.1 similar to YEJL_ECOLI gi|1788514 (conserved in Escherichia coli K-12) NP_311107.1 similar to YEJM_ECOLI gi|1788515 (conserved in Escherichia coli K-12) NP_311108.1 similar to YEJO_ECOLI gi|1788516 (conserved in Escherichia coli K-12) NP_311109.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes NP_311110.1 similar to CCMH_ECOLI gi|1788522 (conserved in Escherichia coli K-12); cytochrome c-type biogenesis protein NP_311111.1 similar to DSBE_ECOLI gi|1788523 (conserved in Escherichia coli K-12); thiol:disulfide interchange protein NP_311112.1 similar to CCMF_ECOLI gi|1788524 (conserved in Escherichia coli K-12) NP_311113.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane NP_311114.1 similar to CCMD_ECOLI gi|1788526 (conserved in Escherichia coli K-12) NP_311115.1 similar to CCMC_ECOLI gi|1788527 (conserved in Escherichia coli K-12) NP_311116.1 similar to CCMB_ECOLI gi|1788528 (conserved in Escherichia coli K-12) NP_311117.1 ATP-binding protein; required for proper cytochrome c maturation NP_311118.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone NP_311119.2 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA NP_311120.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA NP_311121.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway NP_311122.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC NP_311123.1 similar to NAPD_ECOLI gi|1788535 (conserved in Escherichia coli K-12) NP_311124.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA. NP_311125.1 serine protease inhibitor, inhibits trypsin and other proteases NP_311126.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate NP_311127.1 efflux pump for the antibacterial peptide microcin J25 NP_311128.1 similar to ALKB_ECOLI gi|1788541 (conserved in Escherichia coli K-12) NP_311129.1 similar to ADA_ECOLI gi|1788542 (conserved in Escherichia coli K-12) NP_311130.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway NP_311131.1 allows for ions and hydrophilic solutes to cross the outer membrane NP_311132.1 similar to YOJN_ECOLI gi|1788545 (conserved in Escherichia coli K-12) NP_311133.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF NP_311134.2 similar to RCSC_ECOLI gi|1788548 (conserved in Escherichia coli K-12) NP_311135.1 similar to B2225_ECOLI gi|1788556 (conserved in Escherichia coli K-12) NP_311136.1 similar to C-terminal part of B2226_ECOLI gi|1788557; may contain frameshift NP_311137.1 similar to N-terminal part of B2226_ECOLI gi|1788557; may contain frameshift NP_311138.1 similar to membrane protein B2228_ECOLI gi|1788559, B2227_ECOLI to gi|1788558 NP_311139.2 similar to B2229_ECOLI gi|1788560 (conserved in Escherichia coli K-12) NP_311140.2 similar to YFAA_ECOLI gi|1788561 NP_311141.1 negatively supercoils closed circular double-stranded DNA NP_311142.1 Involved in ubiquinone biosynthesis NP_311143.1 similar to YFAL_ECOLI gi|1788565 (conserved in Escherichia coli K-12) NP_311144.1 Catalyzes the rate-limiting step in dNTP synthesis NP_311145.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA NP_311146.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases NP_311147.1 similar to INAA_ECOLI gi|1788569 (conserved in Escherichia coli K-12) NP_311148.1 similar to antibiotic resistance protein homolog YwoG [Bacillus subtilis] gi|7474437|pir||B70065 NP_311149.1 similar to transcriptional regulators e.g. YvbU [Bacillus subtilis] gi|6648030|sp|O32255 NP_311151.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic NP_311152.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell NP_311153.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor NP_311154.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters NP_311155.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate NP_311156.1 similar to YFAD_ECOLI gi|1788577 (conserved in Escherichia coli K-12) NP_311157.1 similar to B2245_ECOLI gi|1788578 (conserved in Escherichia coli K-12) NP_311158.1 similar to transport protein B2246_ECOLI gi|1788579 NP_311159.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein gi|7444868|pir||T00241 NP_311160.1 OrfB protein of insertion sequence IS629; similar to gi|7443862|pir||T00240 NP_311161.1 similar to B2246_ECOLI gi|1788579 NP_311162.1 similar to B2247_ECOLI gi|1788580 (conserved in Escherichia coli K-12) NP_311163.1 similar to B2248_ECOLI gi|1788581 (conserved in Escherichia coli K-12) NP_311164.1 similar to B2249_ECOLI gi|1788583 (conserved in Escherichia coli K-12) NP_311165.2 similar to B2250_ECOLI gi|1788584 (conserved in Escherichia coli K-12) NP_311166.1 similar to YFAO_ECOLI gi|1788585 (conserved in Escherichia coli K-12) NP_311167.1 similar to AIS_ECOLI gi|1788586 (conserved in Escherichia coli K-12) NP_311168.3 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose NP_311169.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate NP_311170.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains NP_311171.1 similar to B2256_ECOLI gi|1788590 (conserved in Escherichia coli K-12) NP_311172.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A NP_311173.2 similar to B2258_ECOLI gi|1788592 (conserved in Escherichia coli K-12) NP_311174.1 similar to PMRD_ECOLI gi|1788593 (conserved in Escherichia coli K-12) NP_311175.1 similar to MENE_ECOLI gi|1788595 (conserved in Escherichia coli K-12) NP_311176.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate NP_311177.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA NP_311178.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA NP_311179.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis NP_311180.2 synthesizes isochorismate acid from chorismate NP_311181.1 similar to ELAB_ECOLI gi|1788601 (conserved in Escherichia coli K-12) NP_311182.1 similar to ELAA_ECOLI gi|1788602 (conserved in Escherichia coli K-12) NP_311183.2 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions NP_311184.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system NP_311185.1 similar to aminopeptidase YFBL_ECOLI gi|1788607 NP_311186.1 similar to YFBM_ECOLI gi|1788608 (conserved in Escherichia coli K-12) NP_311187.2 Catalyzes the transfer of electrons from NADH to quinone NP_311188.1 Catalyzes the transfer of electrons from NADH to quinone NP_311189.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_311190.1 Catalyzes the transfer of electrons from NADH to quinone NP_311191.1 Catalyzes the transfer of electrons from NADH to quinone NP_311192.1 Catalyzes the transfer of electrons from NADH to quinone NP_311193.1 Catalyzes the transfer of electrons from NADH to quinone NP_311194.2 Catalyzes the transfer of electrons from NADH to quinone NP_311195.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase NP_311196.1 Catalyzes the transfer of electrons from NADH to quinone NP_311197.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms NP_311198.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen NP_311199.2 Catalyzes the transfer of electrons from NADH to quinone NP_311200.1 similar to LRHA_ECOLI gi|1788626 (conserved in Escherichia coli K-12) NP_311201.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor NP_311202.1 similar to B2291_ECOLI gi|1788628 (conserved in Escherichia coli K-12) NP_311203.1 similar to YFBS_ECOLI gi|1788629 (conserved in Escherichia coli K-12) NP_311204.1 similar to YFBT_ECOLI gi|1788630 (conserved in Escherichia coli K-12) NP_311205.2 similar to B2294_ECOLI gi|1788631 (conserved in Escherichia coli K-12) NP_311206.1 similar to N-terminal part of B2295_ECOLI gi|1788632 (conserved in Escherichia coli K-12) NP_311207.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA NP_311208.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate NP_311209.2 similar to YFCC_ECOLI gi|1788636 (conserved in Escherichia coli K-12) NP_311210.1 similar to B2299_ECOLI gi|1788637 (conserved in Escherichia coli K-12) NP_311211.2 similar to YFCE_ECOLI gi|1788638 (conserved in Escherichia coli K-12) NP_311212.1 similar to YFCF_ECOLI gi|1788639 (conserved in Escherichia coli K-12) NP_311213.1 similar to YFCG_ECOLI gi|1788640 (conserved in Escherichia coli K-12) NP_311214.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate NP_311215.1 similar to B2304_ECOLI gi|1788642 (conserved in Escherichia coli K-12) NP_311216.1 similar to YFCI_ECOLI gi|1788643 (conserved in Escherichia coli K-12) NP_311217.1 similar to HISP_ECOLI gi|1788644 (conserved in Escherichia coli K-12) NP_311218.1 similar to HISM_ECOLI gi|1788645 (conserved in Escherichia coli K-12) NP_311219.1 similar to HISQ_ECOLI gi|1788646 (conserved in Escherichia coli K-12) NP_311220.1 similar to HISJ_ECOLI gi|1788648 (conserved in Escherichia coli K-12) NP_311221.1 similar to ARGT_ECOLI gi|1788649 (conserved in Escherichia coli K-12) NP_311222.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate NP_311223.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway NP_311224.1 membrane protein required for colicin V production NP_311225.2 similar to DEDD_ECOLI gi|1788653 (conserved in Escherichia coli K-12) NP_311226.1 similar to FOLC_ECOLI gi|1788654 (conserved in Escherichia coli K-12) NP_311227.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_311228.1 similar to DEDA_ECOLI gi|1788656 (conserved in Escherichia coli K-12) NP_311229.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability NP_311230.1 similar to USG_ECOLI gi|1788658 (conserved in Escherichia coli K-12) NP_311231.1 catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate NP_311232.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein NP_311233.1 similar to B2322_ECOLI gi|1788662 (conserved in Escherichia coli K-12) NP_311234.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_311235.2 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules NP_311236.1 similar to B2325_ECOLI gi|1788665 (conserved in Escherichia coli K-12) NP_311237.1 similar to B2326_ECOLI gi|1788666 (conserved in Escherichia coli K-12) NP_311238.1 similar to YFCA_ECOLI gi|1788667 (conserved in Escherichia coli K-12) NP_311239.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm NP_311240.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_311241.2 involved in methylation of ribosomal protein L3 NP_311242.1 similar to B2331_ECOLI gi|1788671 (conserved in Escherichia coli K-12) NP_311243.1 similar to B2332_ECOLI gi|7466328|pir||B65006 NP_311244.1 similar to B2333_ECOLI gi1788674, minor fimbrial subunit StfG protein [Salmonella typhimurium] dad|AF093503-7|AAC64157.1 NP_311245.1 similar to B2334_ECOLI gi|1788675, minor fimbrial subunits e.g. StfF [Salmonella typhimurium] gi3747033 NP_311246.1 similar to B2335_ECOLI gi|1788676, minor fimbrial subunit StfE protein [Salmonella typhimurium] dad|AF093503-5|AAC64155.1 NP_311247.1 similar to YFCS_ECOLI gi|1788677, periplasmic fimbrial chaperone StfD protein [Salmonella typhimurium] dad|AF093503-4|AAC64154.1 NP_311248.1 similar to YFCU_ECOLI gi|1788679, B2337_ECOLI gi|1788678 NP_311249.1 similar to B2339_ECOLI gi|1788680, major fimbrial subunit StfA protein [Salmonella typhimurium ] dad|AF093503-2|AAC64152.1 NP_311250.1 similar to B2340_ECOLI gi|1788681 (conserved in Escherichia coli K-12) NP_311251.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate NP_311252.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth NP_311253.2 similar to B2343_ECOLI gi|1788685 (conserved in Escherichia coli K-12) NP_311254.1 similar to FADL_ECOLI gi|1788686 (conserved in Escherichia coli K-12) NP_311255.1 similar to B2345_ECOLI gi|1788687 NP_311256.1 similar to VACJ_ECOLI gi|1788688 (conserved in Escherichia coli K-12) NP_311257.1 similar to YFDC_ECOLI gi|1788689 (conserved in Escherichia coli K-12) NP_311258.1 similar to INTC_ECOLI gi|1788690 (conserved in Escherichia coli K-12) NP_311259.1 similar to DNA injection protein gp20 [phage P22] gi|1174950|sp|Q01076|VG20_BPP22 NP_311260.1 similar to DNA transfer protein Gp7 [Bacteriophage P22] gi|418222|sp|Q01074|VG07_BPP22 NP_311261.1 similar to hypothetical protein P31 [Bacteriophage APSE-1] gi|6118026|gb|AAF03974.1|AF157835_31, gp14 [Bacteriophage P22] gi|418225|sp|Q01075|VG14_BPP22 NP_311263.1 similar to replication proteins e.g. [Haemophilus actinomycetemcomitans Plasmid pVT736-1] gi|398106|gb|AAC37125.1| NP_311267.1 similar to resolvases e.g. [Plasmid pM3] gi|5668998|gb|AAD46124.1|AF078924_3, [Yersinia pestis plasmid pMT1] gi|7467461|pir||T14990 NP_311268.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments NP_311269.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least NP_311270.1 similar to sucrose hydrolase [Escherichia coli strain EC3132] gi|3462879|gb|AAC33123.1 NP_311271.1 similar to sucrose operon repressor [Escherichia coli] gi|729214|sp|P40715|CSCR_ECOLI NP_311272.1 catalyzes the formation of pyruvate from serine NP_311273.1 similar to EMRY_ECOLI gi|1788710 (conserved in Escherichia coli K-12) NP_311274.1 similar to EMRK_ECOLI gi|1788711 (conserved in Escherichia coli K-12) NP_311275.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance NP_311276.1 similar to EVGS_ECOLI gi|1788713 (conserved in Escherichia coli K-12) NP_311277.1 similar to YFDE_ECOLI gi|1788714 NP_311278.1 similar to YFDE_ECOLI gi|1788714 NP_311279.1 member of the AEC family of auxin efflux transporters; unknown function NP_311280.1 catalyzes the formation of formyl-CoA from oxalyl-CoA NP_311281.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA NP_311282.1 similar to B2375_ECOLI gi|1788719 (conserved in Escherichia coli K-12) NP_311283.1 similar to B2376_ECOLI gi|2367134 (conserved in Escherichia coli K-12) NP_311284.1 similar to B2377_ECOLI gi|1788720 (conserved in Escherichia coli K-12) NP_311285.2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock NP_311286.1 similar to B2379_ECOLI gi|1788722 (conserved in Escherichia coli K-12) NP_311287.1 similar to B2380_ECOLI gi|1788723 (conserved in Escherichia coli K-12) NP_311288.1 similar to B2381_ECOLI gi|1788724 (conserved in Escherichia coli K-12) NP_311289.1 similar to B2382_ECOLI gi|1788725 (conserved in Escherichia coli K-12) NP_311290.1 similar to B2383_ECOLI gi|1788726 (conserved in Escherichia coli K-12) NP_311291.1 metalloprotein NP_311292.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase NP_311293.1 similar to B2386_ECOLI gi|1788729 (conserved in Escherichia coli K-12) NP_311294.1 similar to B2387_ECOLI gi|1788730 (conserved in Escherichia coli K-12) NP_311295.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate NP_311296.1 similar to B2389_ECOLI gi|1788733 (conserved in Escherichia coli K-12) NP_311297.1 similar to B2390_ECOLI gi|1788734 (conserved in Escherichia coli K-12) NP_311298.1 similar to B2392_ECOLI (MntH) gi|1788736|sp|P77145 (conserved in Escherichia coli K-12) NP_311299.1 similar to NUPC_ECOLI gi|1788737 (conserved in Escherichia coli K-12) NP_311300.1 similar to YFEA_ECOLI gi|1788739 (conserved in Escherichia coli K-12) NP_311301.1 similar to YFEC_ECOLI gi|1788741 (conserved in Escherichia coli K-12) NP_311302.1 similar to YFED_ECOLI gi|1788742 (conserved in Escherichia coli K-12) NP_311303.2 similar to EryA homologue [Bacteriophage If1] dad|U02303-9|AAC62159.1 NP_311304.1 similar to transposase homolog A [Helicobacter pylori] gi|2114470|gb|AAD11513.1 NP_311305.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_311306.1 similar to FLXA_ECOLI gi|2498386|sp|P77609 NP_311307.1 similar to transcriptional regulator YFER_ECOLI gi|1788748; may contain frameshift NP_311308.1 similar to transcriptional regulator YFER_ECOLI gi|1788748; may contain frameshift NP_311309.1 similar to YFEH_ECOLI gi|1788749 (conserved in Escherichia coli K-12) NP_311310.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_311311.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure NP_311312.1 role in sulfur assimilation NP_311313.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis NP_311314.1 similar to PTSH_ECOLI gi|1788755 (conserved in Escherichia coli K-12) NP_311315.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system NP_311316.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose NP_311317.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal NP_311318.1 similar to YFEK_ECOLI gi|1788759 NP_311319.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide NP_311320.1 similar to CYSA_ECOLI gi|1788761 (conserved in Escherichia coli K-12) NP_311321.2 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import NP_311322.1 similar to CYSU_ECOLI gi|1788764 (conserved in Escherichia coli K-12) NP_311323.1 similar to CYSP_ECOLI gi|1788765 (conserved in Escherichia coli K-12) NP_311324.2 similar to UCPA_ECOLI gi|1788766 (conserved in Escherichia coli K-12) NP_311325.1 similar to YFET_ECOLI gi|1788767 (conserved in Escherichia coli K-12) NP_311326.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway NP_311327.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component NP_311328.1 similar to beta-lactamase B2430_ECOLI gi|1788770 (conserved in Escherichia coli K-12) NP_311329.2 similar to B2431_ECOLI gi|1788771 (conserved in Escherichia coli K-12) NP_311330.1 similar to B2432_ECOLI gi|1788772 (conserved in Escherichia coli K-12) NP_311331.2 similar to B2433_ECOLI gi|1788773 (conserved in Escherichia coli K-12) NP_311332.2 similar to B2434_ECOLI gi|1788774 (conserved in Escherichia coli K-12) NP_311333.1 similar to AMIA_ECOLI gi|1788776 (conserved in Escherichia coli K-12) NP_311334.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis NP_311335.1 activates the transcription of the ethanolamine utilization operon NP_311336.2 similar to B2438_ECOLI gi|1788779 (conserved in Escherichia coli K-12) NP_311337.1 similar to B2439_ECOLI gi|1788780 (conserved in Escherichia coli K-12) NP_311338.1 catalyzes the formation of acetaldehyde from ethanolamine NP_311339.1 similar to EUTB_ECOLI gi|1788782 (conserved in Escherichia coli K-12) NP_311340.1 ethanolamine utilization protein EutA NP_311341.1 similar to EUTH_ECOLI gi|1788794 (conserved in Escherichia coli K-12); ethanolamine utilization protein NP_311342.2 similar to EUTG_ECOLI gi|1788795 (conserved in Escherichia coli K-12) NP_311343.1 similar to EUTJ_ECOLI gi|1788796 (conserved in Escherichia coli K-12); ethanolamine utilization protein NP_311344.1 similar to EUTE_ECOLI gi|1788797 (conserved in Escherichia coli K-12); ethanolamine utilization protein NP_311345.1 similar to CCHB_ECOLI gi|1788798 (conserved in Escherichia coli K-12) NP_311346.2 similar to CCHA_ECOLI gi|1788799 (conserved in Escherichia coli K-12) NP_311347.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta NP_311348.1 similar to B2459_ECOLI gi|1788801 (conserved in Escherichia coli K-12) NP_311349.1 similar to B2460_ECOLI gi|1788802 (conserved in Escherichia coli K-12) NP_311350.1 similar to B2461_ECOLI gi|1788803 (conserved in Escherichia coli K-12) NP_311351.2 similar to B2462_ECOLI gi|1788804 (conserved in Escherichia coli K-12) NP_311352.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate NP_311353.1 Maintains the balance of metabolites in the pentose-phosphate pathway NP_311354.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_311355.1 similar to B2466_ECOLI gi|1788809 (conserved in Escherichia coli K-12) NP_311356.1 similar to YFFH_ECOLI gi|1788810 (conserved in Escherichia coli K-12) NP_311357.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) NP_311358.1 similar to NARQ_ECOLI gi|1788812 (conserved in Escherichia coli K-12) NP_311359.1 similar to ACRD_ECOLI gi|1788814 (conserved in Escherichia coli K-12) NP_311360.1 similar to YFFB_ECOLI gi|1788815 (conserved in Escherichia coli K-12) NP_311361.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. NP_311362.2 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate NP_311363.1 similar to YPFI_ECOLI gi|1788818 (conserved in Escherichia coli K-12) NP_311364.1 similar to B2475_ECOLI gi|1788819 (conserved in Escherichia coli K-12) NP_311365.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase NP_311366.2 similar to NLPB_ECOLI gi|1788822 (conserved in Escherichia coli K-12) NP_311367.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_311368.2 negative transcriptional regulator of the gcvTHP operon NP_311369.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine NP_311370.2 similar to HYFA_ECOLI gi|1788826 (conserved in Escherichia coli K-12) NP_311371.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_311372.2 similar to HYFC_ECOLI gi|1788828 (conserved in Escherichia coli K-12) NP_311373.1 similar to HYFD_ECOLI gi|1788829 (conserved in Escherichia coli K-12) NP_311374.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide NP_311375.1 Catalyzes the transfer of electrons from NADH to ubiquinone NP_311376.1 similar to HYFG_ECOLI gi|1788832 NP_311377.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far NP_311378.1 similar to HYFI_ECOLI gi|1788834 (conserved in Escherichia coli K-12) NP_311379.1 similar to B2490_ECOLI gi|1788835 (conserved in Escherichia coli K-12) NP_311380.2 similar to HYFR_ECOLI gi|1788836 (conserved in Escherichia coli K-12) NP_311381.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon NP_311382.1 similar to PERM_ECOLI gi|1788838 (conserved in Escherichia coli K-12) NP_311383.1 similar to B2494_ECOLI gi|1788840 (conserved in Escherichia coli K-12) NP_311384.1 similar to B2495_ECOLI gi|1788841 (conserved in Escherichia coli K-12) NP_311385.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP NP_311386.1 similar to URAA_ECOLI gi|1788843 (conserved in Escherichia coli K-12) NP_311387.2 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate NP_311388.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis NP_311389.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate NP_311390.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate NP_311391.1 similar to PPX_ECOLI gi|1788848 (conserved in Escherichia coli K-12) NP_311392.1 similar to B2503_ECOLI gi|1788849 (conserved in Escherichia coli K-12) NP_311393.1 similar to B2504_ECOLI gi|1788851 (conserved in Escherichia coli K-12) NP_311394.1 similar to B2505_ECOLI gi|1788852 (conserved in Escherichia coli K-12) NP_311395.1 similar to B2506_ECOLI gi|1788853 (conserved in Escherichia coli K-12) NP_311396.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_311397.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate NP_311398.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_311399.1 similar to B2510_ECOLI gi|1788857 (conserved in Escherichia coli K-12) NP_311400.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_311401.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis NP_311402.1 similar to B2513_ECOLI gi|1788860 (conserved in Escherichia coli K-12) NP_311403.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_311404.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis NP_311405.1 similar to YFGA_ECOLI gi|1788864 (conserved in Escherichia coli K-12) NP_311406.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance NP_311407.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_311408.1 similar to ferredoxin [Methanosarcina thermophila] gi|282643|pir||A42960, polyferredoxin [Methanococcus voltae] gi|99156|pir||S24802 NP_311409.1 similar to anaerobic dimethyl sulfoxide reductase chain C e.g. [Escherichia coli] gi|118699|sp|P18777|DMSC_ECOLI NP_311410.1 similar to anaerobic dimethyl sulfoxide reductases chain B e.g. [Escherichia coli] gi|2506394|sp|P18776|DMSB_ECOLI NP_311411.1 similar to anaerobic dimethyl sulfoxide reductase chain A precursors e.g. [Escherichia coli] gi|118697|sp|P18775|DMSA_ECOLI NP_311412.1 penicillin-insensitive transglycosylase/transpeptidase NP_311413.1 similar to B2520_ECOLI gi|1788868 (conserved in Escherichia coli K-12) NP_311414.2 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds NP_311415.2 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I NP_311416.2 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide NP_311417.1 similar to YFHJ_ECOLI gi|1788873 (conserved in Escherichia coli K-12) NP_311418.1 similar to FER_ECOLI gi|119999|sp|P25528 (conserved in Escherichia coli K-12) NP_311419.1 involved in the maturation of iron-sulfur cluster-containing proteins NP_311420.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins NP_311421.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein NP_311422.1 similar to ISCU_ECOLI gi|7387937|sp|P77310 (conserved in Escherichia coli K-12) NP_311423.2 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis NP_311424.1 regulates the expression of the iscRSUA operon NP_311425.1 similar to B2532_ECOLI (YhfQ) gi|1788881 (conserved in Escherichia coli K-12) NP_311426.1 similar to SUHB_ECOLI gi|1788882 (conserved in Escherichia coli K-12) NP_311427.2 similar to B2534_ECOLI gi|1788884 (conserved in Escherichia coli K-12) NP_311428.2 similar to CSIE_ECOLI gi|1788885 (conserved in Escherichia coli K-12) NP_311429.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters NP_311430.1 activator of 3-phenylpropionic acid catabolism NP_311431.1 similar to HCAA1_ECOLI gi|1788888 (conserved in Escherichia coli K-12) NP_311432.1 similar to HCAA2_ECOLI gi|1788889 (conserved in Escherichia coli K-12) NP_311433.1 similar to HCAC_ECOLI gi|1788890 (conserved in Escherichia coli K-12) NP_311434.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate NP_311435.1 similar to HCAD_ECOLI gi|1788892 (conserved in Escherichia coli K-12) NP_311436.2 similar to YPHA_ECOLI gi|1788893 (conserved in Escherichia coli K-12) NP_311437.1 similar to YPHB_ECOLI gi|1788894 (conserved in Escherichia coli K-12) NP_311438.1 similar to YPHC_ECOLI gi|1788895 NP_311439.1 similar to YPHD_ECOLI gi|1788896 (conserved in Escherichia coli K-12) NP_311440.1 similar to YPHE_ECOLI gi|1788897 (conserved in Escherichia coli K-12) NP_311441.1 similar to YPHF_ECOLI gi|1788898 (conserved in Escherichia coli K-12) NP_311442.1 similar to YPHG_ECOLI gi|1788900 (conserved in Escherichia coli K-12) NP_311443.2 similar to YPHH_ECOLI gi|1788901 (conserved in Escherichia coli K-12) NP_311444.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_311445.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine NP_311446.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA NP_311447.1 similar to YFHA_ECOLI gi|1788905 (conserved in Escherichia coli K-12) NP_311448.1 similar to YFHG_ECOLI gi|1788906 (conserved in Escherichia coli K-12) NP_311449.1 similar to YFHK_ECOLI gi|1788908 (conserved in Escherichia coli K-12) NP_311450.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis NP_311451.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function NP_311452.1 similar to YFHC_ECOLI gi|1788911 (conserved in Escherichia coli K-12) NP_311453.2 similar to YFHB_ECOLI gi|1788912 (conserved in Escherichia coli K-12) NP_311454.2 similar to YFHH_ECOLI gi|1788913 (conserved in Escherichia coli K-12) NP_311455.1 similar to YFHL_ECOLI gi|1788914 (conserved in Escherichia coli K-12) NP_311456.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_311457.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) NP_311458.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_311459.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome NP_311460.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_311461.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins NP_311462.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_311463.1 involved in the reduction of the SoxR iron-sulfur cluster NP_311464.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP NP_311465.1 similar to RSEA_ECOLI gi|1788925 (conserved in Escherichia coli K-12) NP_311466.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response NP_311467.1 catalyzes the formation of oxaloacetate from L-aspartate NP_311468.1 similar to YFIC_ECOLI gi|1788929 (conserved in Escherichia coli K-12) NP_311469.1 facilitates an early step in the assembly of the 50S subunit of the ribosome NP_311470.2 similar to YFIE_ECOLI gi|1788931 (conserved in Escherichia coli K-12) NP_311471.1 similar to YFIK_ECOLI gi|1788932 (conserved in Escherichia coli K-12) NP_311472.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit NP_311473.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_311474.1 similar to YFIF_ECOLI gi|1788935 (conserved in Escherichia coli K-12) NP_311475.1 similar to TRXC_ECOLI gi|1788936 (conserved in Escherichia coli K-12) NP_311476.2 similar to YFIP_ECOLI gi|1788937 (conserved in Escherichia coli K-12) NP_311479.2 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome NP_311480.1 similar to YFIM_ECOLI gi|1788941 (conserved in Escherichia coli K-12) NP_311481.1 similar to KGTP_ECOLI gi|1788942 (conserved in Escherichia coli K-12) NP_311482.1 similar to CLPB_ECOLI gi|1788943 (conserved in Escherichia coli K-12) NP_311483.1 similar to YFIH_ECOLI gi|1788945 (conserved in Escherichia coli K-12) NP_311484.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA NP_311485.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline NP_311486.1 similar to B2596_ECOLI gi|1788948 (conserved in Escherichia coli K-12) NP_311487.1 associated with 30S ribosomal subunit; interferes with translation elongation NP_311489.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis NP_311490.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis NP_311491.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive NP_311492.1 similar to YFIL_ECOLI gi|1788954 (conserved in Escherichia coli K-12) NP_311493.1 similar to B2603_ECOLI gi|1788955 (conserved in Escherichia coli K-12) NP_311494.1 similar to YFIN_ECOLI gi|1788956 (conserved in Escherichia coli K-12) NP_311495.1 similar to YFIB_ECOLI gi|1788957 (conserved in Escherichia coli K-12) NP_311496.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_311497.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA NP_311498.3 Essential for efficient processing of 16S rRNA NP_311499.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_311500.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins NP_311501.2 similar to B2611_ECOLI gi|1788964 (conserved in Escherichia coli K-12) NP_311502.1 similar to YPJE_ECOLI gi|1788965, YFJD_ECOLI gi|1788966 NP_311503.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor NP_311504.1 catalyzes the phosphorylation of NAD to NADP NP_311505.1 similar to RECN_ECOLI gi|1788969 (conserved in Escherichia coli K-12) NP_311506.1 similar to SMPA_ECOLI gi|1788970 (conserved in Escherichia coli K-12) NP_311507.2 similar to B2618_ECOLI gi|1788971 (conserved in Escherichia coli K-12) NP_311508.1 similar to B2619_ECOLI gi|1788972 (conserved in Escherichia coli K-12) NP_311509.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_311510.1 similar to DNA damage-inducible proteins e.g. DinI [Escherichia coli] gi|2498305|sp|Q47143|DINI_ECOLI NP_311512.1 similar to TrcA-like proteins e.g. bfpT-regulated chaperone-like protein TrcA [Escherichia coli strain B171-8] gi|4126789|dbj|BAA36747.1| NP_311513.1 similar to hypothetical proteins e.g. ORF2 [Escherichia coli strain B171-8] gi|4126790|dbj|BAA36748.1| NP_311514.1 similar to hypothetical protein ORF3 [Escherichia coli strain B171-8] gi|4126791|dbj|BAA36749.1| NP_311515.1 similar to hypothetical proteins e.g. ORF4 [Escherichia coli strain B171-8] gi|4126792|dbj|BAA36750.1| NP_311516.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585437|gb|AAD25465.1|AF125520_60 NP_311517.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7444868|pir||T00241, hypothetical proteins of IS elements e.g. TnpE [Shigella flexneri] gi|5532454|gb|AAD44738.1|AF141323_9 NP_311518.1 OrfB protein of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 insertion sequence IS629] gi|7443862|pir||T00240 NP_311519.1 similar to hypothetical protein L0015 Escherichia coli O157:H7 strain EDL933 AAC31494 NP_311520.1 similar to hypothetical protein L0014 [Escherichia coli O157:H7 strain EDL933] gi|3288157|emb|CAA11510.1|, similar tohypothetical proteins e.g. ORF50 [Escherichia coli] gi|6009426|dbj|BAA84885.1| NP_311521.1 similar to hypothetical proteins e.g. L0013 [Escherichia coli O157:H7 strain EDL933] gi|3414881|gb|AAC31492.1| NP_311523.1 similar to hypothetical protein YdfR [Escherichia coli] gi|3183262|sp|P76160|YDFR_ECOLI NP_311524.1 host cell lysis; similar to holins e.g. [Bacteriophage VT2-Sa] gi|5881636|dbj|BAA84327.1| NP_311525.1 similar to hypothetical protein [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_311527.2 similar to hypothetical protein [Actinobacillus actinomycetemcomitans] gi|7592819|dbj|BAA94406.1 NP_311528.1 similar to antitermination proteins e.g. protein Q [Bacteriophage lambda] gi|132278|sp|P03047|REGQ_LAMBD NP_311529.1 similar to serine/threonine protein phosphatases e.g. [Bacteriophage lambda] gi|130792|sp|P03772|PP_LAMBD NP_311530.1 similar to hypothetical proteins e.g. NinG [Bacteriophage 21] gi|4539482|emb|CAB39991.1| NP_311531.1 similar to phage hypothetical proteins e.g. [Bacteriophage phi-YeO3-12] gi|6598993|emb|CAB63597.1| NP_311537.1 similar to ctp synthase - Rickettsia prowasekii C71695, hypothetical protein Plasmodium falciparum CAB39033 NP_311539.1 probable integrase; similar to site specific recombinases e.g. integrase-recombinase [Methanobacterium thermoautotrophicum] gi|7428936|pir||D69219 NP_311540.1 similar to Bacteriophage P4 DNA-binding protein P12552 and Yersinia pestis hypothetical protein T17447 NP_311542.1 similar to YPJA_ECOLI gi|1789001 (conserved in Escherichia coli K-12) NP_311544.1 similar to B2650_ECOLI gi|1789004, B2649_ECOLI gi|1789003 NP_311545.1 similar to B2654_ECOLI gi|1789007, B2655_ECOLI similar to gi|1789008 NP_311546.1 similar to B2657_ECOLI gi|1789010, B2658_ECOLI gi|1789012 NP_311547.2 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution NP_311548.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate NP_311549.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent NP_311550.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate NP_311551.1 similar to GABP_ECOLI gi|1789017 (conserved in Escherichia coli K-12) NP_311552.2 regulator of gab gene expression NP_311553.1 similar to YGAU_ECOLI gi|1789019 (conserved in Escherichia coli K-12) NP_311554.1 similar to B2666_ECOLI gi|1789020 (conserved in Escherichia coli K-12) NP_311555.1 similar to B2667_ECOLI gi|1789021 (conserved in Escherichia coli K-12) NP_311556.1 similar to YGAP_ECOLI gi|1789022 (conserved in Escherichia coli K-12) NP_311557.1 similar to STPA_ECOLI gi|1789023 (conserved in Escherichia coli K-12) NP_311558.1 similar to B2670_ECOLI gi|1789025 (conserved in Escherichia coli K-12) NP_311559.1 similar to YGAC_ECOLI gi|1789026 (conserved in Escherichia coli K-12) NP_311560.2 similar to YGAM_ECOLI gi|1789027 (conserved in Escherichia coli K-12) NP_311561.1 similar to regulatory proteins e.g. MocR [Sinorhizobium meliloti] gi|1346565|sp|P49309 NP_311562.1 similar to conserved hypothetical protein [Streptomyces coelicolor A3(2)] gi|7649565|emb|CAB89054.1 NP_311563.1 similar to NRDH_ECOLI gi|1789028 (conserved in Escherichia coli K-12) NP_311564.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF NP_311565.1 Catalyzes the rate-limiting step in dNTP synthesis NP_311566.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE NP_311567.1 with ProWX is involved in the high-affinity uptake of glycine betaine NP_311568.1 with ProVX is involved in the high-affinity uptake of glycine betaine NP_311569.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine NP_311570.1 similar to B2680_ECOLI gi|1789035, B2681_ECOLI gi|1789036 NP_311571.1 similar to B2682_ECOLI gi|1789038 (conserved in Escherichia coli K-12) NP_311572.1 similar to YGAH_ECOLI gi|1789039 (conserved in Escherichia coli K-12) NP_311573.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB NP_311574.1 similar to EMRA_ECOLI gi|1789041 (conserved in Escherichia coli K-12) NP_311575.1 similar to EMRB_ECOLI gi|1789042 (conserved in Escherichia coli K-12) NP_311576.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 NP_311577.1 involved in the first step of glutathione biosynthesis NP_311578.1 similar to B2689_ECOLI gi|1789045 (conserved in Escherichia coli K-12) NP_311579.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent NP_311580.1 affects carbohydrate metabolism; has regulatory role in many processes NP_311581.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_311582.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities NP_311583.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_311584.1 similar to YGAD_ECOLI gi|1789052 (conserved in Escherichia coli K-12) NP_311585.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan NP_311587.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_311588.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate NP_311589.1 regulator for glucitol utilization NP_311590.1 regulates genes involved in glucitol utilization NP_311591.2 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate NP_311592.2 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon NP_311593.1 detoxifies nitric oxide using NADH NP_311594.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase NP_311595.1 similar to HYPF_ECOLI gi|2367152 (conserved in Escherichia coli K-12) NP_311596.1 involved in electron transport from formate to hydrogen NP_311597.1 similar to ASCG_ECOLI gi|1789068 (conserved in Escherichia coli K-12) NP_311598.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_311599.1 similar to ASCB_ECOLI gi|1789070 (conserved in Escherichia coli K-12) NP_311600.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE NP_311601.1 similar to HYCH_ECOLI gi|1789073 (conserved in Escherichia coli K-12) NP_311602.1 similar to HYCG_ECOLI gi|1789074 (conserved in Escherichia coli K-12) NP_311603.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate NP_311604.1 similar to HYCE_ECOLI gi|1789076 (conserved in Escherichia coli K-12) NP_311605.1 similar to HYCD_ECOLI gi|1789077 (conserved in Escherichia coli K-12) NP_311606.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) NP_311607.1 similar to HYCB_ECOLI gi|1789079 (conserved in Escherichia coli K-12) NP_311608.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon NP_311609.1 plays a role in hydrogenase nickel cofactor insertion NP_311610.1 GTP hydrolase involved in nickel liganding into hydrogenases NP_311611.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase NP_311612.1 hydrogenase isoenzyme; similar to HYPD_ECOLI gi|1789084 (conserved in Escherichia coli K-12) NP_311613.1 similar to HYPE_ECOLI gi|1789085 (conserved in Escherichia coli K-12) NP_311614.1 similar to FHLA_ECOLI gi|1789087 (conserved in Escherichia coli K-12) NP_311615.1 similar to YGBA_ECOLI gi|1789088 (conserved in Escherichia coli K-12) NP_311616.1 This protein performs the mismatch recognition step during the DNA repair process NP_311617.1 similar to PPHB_ECOLI gi|1789090 (conserved in Escherichia coli K-12) NP_311618.1 similar to hypothetical proteins e.g. VdcD [Streptomyces sp. D7] gi|4741970|gb|AAD28783.1|AF134589_3, YclD [Bacillus subtilis] gi|7452267|pir||A69762 NP_311619.1 similar to YclC [Escherichia coli O157:H7] gi|4887556|emb|CAB43499.1|, VdcC [Streptomyces sp. D7] gi|6686069|sp|Q9X697|VDCC_STRD7 NP_311620.1 similar to Pad1 [Escherichia coli O157:H7] gi|4887557|emb|CAB43500.1|, phenylacrylic acid decarboxylases e.g. VdcB [Streptomyces sp. D7] NP_311621.1 similar to SlyA [Escherichia coli O157:H7] to gi|4887558|emb|CAB43501.1|, transcriptional regulators e.g. [Streptomyces coelicolor] gi|7481485|pir||T35022 NP_311622.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses NP_311623.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus NP_311624.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins NP_311625.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate NP_311626.1 catalyzes the modification of U13 in tRNA(Glu) NP_311627.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_311628.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_311629.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein NP_311630.1 similar to YGBE_ECOLI gi|1789106 (conserved in Escherichia coli K-12) NP_311631.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis NP_311632.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ NP_311633.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP NP_311634.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 NP_311635.1 similar to hypothetical protein [Escherichia coli] gi|7404494|sp|P45956|YGBF_ECOLI NP_311636.1 similar to hypothetical protein b2755 [Escherichia coli strain K-12] gi|7460139|pir||G65056 NP_311637.1 similar to hypothetical protein b2756 [Escherichia coli strain K-12] gi|6136707|sp|Q46897|YGCH_ECOLI NP_311638.1 similar to hypothetical protein b2757 [Escherichia coli strain K-12] gi|7459357|pir||A65057 NP_311639.1 similar to hypothetical protein b2758 [Escherichia coli strain K-12] gi|7476186|pir||C70849 NP_311641.1 similar to hypothetical protein b2760 [Escherichia coli strain K-12] gi|7451979|pir||D65057 NP_311642.1 similar to hypothetical protein YgcB [Escherichia coli strain K-12] gi|2506493|sp|P38036|YGCB_ECOLI NP_311643.1 similar to YBDY_ECOLI gi|3025009|sp|P77091, SrnB [Plasmid F] dad|AP001918-5|BAA97875.1 NP_311644.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite NP_311645.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide NP_311646.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity NP_311647.1 similar to YGCM_ECOLI gi|1789124 (conserved in Escherichia coli K-12) NP_311648.2 similar to YGCN_ECOLI gi|1789125 (conserved in Escherichia coli K-12) NP_311649.1 similar to YGCO_ECOLI gi|1789126 (conserved in Escherichia coli K-12) NP_311650.1 similar to YGCP_ECOLI gi|1789127 (conserved in Escherichia coli K-12) NP_311653.1 similar to YGCR_ECOLI gi|2367158 (conserved in Escherichia coli K-12) NP_311656.1 similar to YGCU_ECOLI gi|2367159, B2772_ECOLI gi|1789131 NP_311657.2 similar to YGCW_ECOLI gi|1789135 (conserved in Escherichia coli K-12) NP_311658.1 similar to YQCE_ECOLI gi|2367161 (conserved in Escherichia coli K-12) NP_311659.1 similar to YGCE_ECOLI gi|1789138 (conserved in Escherichia coli K-12) NP_311660.1 similar to YGCF_ECOLI gi|1789139 (conserved in Escherichia coli K-12) NP_311661.1 similar to hypothetical proteins e.g. Tp70 [Treponema pallidum] gi|7521576|pir||A71309 NP_311662.1 similar to N-terminal parts of hypothetical proteins e.g. YgcG [Escherichia coli] gi|1723817|sp|P55140|YGCG_ECOLI NP_311664.1 similar to hypothetical protein YgcG Escherichia coli P55140 NP_311665.2 similar to YGCG_ECOLI gi|1789140, hypothetical protein [Pseudomonas aeruginosa] dad|AE004490-5|AAG03925.1 NP_311666.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_311667.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_311668.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era NP_311669.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system NP_311670.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF NP_311671.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP NP_311672.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] NP_311673.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system NP_311674.1 similar to YGCX_ECOLI gi|1789150 (conserved in Escherichia coli K-12) NP_311675.1 similar to YGCY_ECOLI gi|1789151 NP_311676.1 similar to B2789_ECOLI gi|1789152 (conserved in Escherichia coli K-12) NP_311677.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_311678.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp NP_311679.1 similar to B2792_ECOLI gi|1789156 (conserved in Escherichia coli K-12) NP_311680.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function NP_311681.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis NP_311682.1 similar to YGDH_ECOLI gi|1789159 (conserved in Escherichia coli K-12) NP_311683.1 similar to SDAC_ECOLI gi|1789160 (conserved in Escherichia coli K-12) NP_311684.1 similar to SDAA_ECOLI gi|1788116 (conserved in Escherichia coli K-12) NP_311685.2 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups NP_311686.1 similar to FUCO_ECOLI gi|1789163 (conserved in Escherichia coli K-12) NP_311687.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate NP_311688.1 similar to FUCP_ECOLI gi|1789166 (conserved in Escherichia coli K-12) NP_311689.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose NP_311690.1 similar to FUCK_ECOLI gi|1789168 (conserved in Escherichia coli K-12) NP_311691.1 similar to FUCU_ECOLI gi|1789169 (conserved in Escherichia coli K-12) NP_311692.1 regulates expression of genes involved in L-fucose utilization NP_311693.1 similar to YGDE_ECOLI gi|1789171 (conserved in Escherichia coli K-12) NP_311694.1 similar to YGDD_ECOLI gi|1789172 (conserved in Escherichia coli K-12) NP_311695.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence NP_311696.1 similar to B2809_ECOLI gi|1789174 (conserved in Escherichia coli K-12) NP_311697.1 similar to B2810_ECOLI gi|1789175 (conserved in Escherichia coli K-12) NP_311698.1 similar to YGDK_ECOLI gi|1789176 (conserved in Escherichia coli K-12) NP_311699.1 similar to YGDL_ECOLI gi|1789177 (conserved in Escherichia coli K-12) NP_311700.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues NP_311701.2 similar to B2817_ECOLI gi|1789180 (conserved in Escherichia coli K-12) NP_311702.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis NP_311703.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity NP_311704.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity NP_311705.1 similar to PTR_ECOLI gi|2367164 (conserved in Escherichia coli K-12) NP_311706.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination NP_311707.1 similar to PPDC_ECOLI gi|1789187 (conserved in Escherichia coli K-12) NP_311708.2 similar to YGDB_ECOLI gi|1789188 (conserved in Escherichia coli K-12) NP_311709.1 similar to PPDB_ECOLI gi|1789189 (conserved in Escherichia coli K-12) NP_311710.1 similar to PPDA_ECOLI gi|1789190 (conserved in Escherichia coli K-12) NP_311711.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived NP_311712.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_311713.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr NP_311714.1 hydrolyzes diadenosine polyphosphate NP_311715.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair NP_311716.1 similar to B2832_ECOLI gi|1789197 (conserved in Escherichia coli K-12) NP_311717.1 similar to B2833_ECOLI gi|1789198 (conserved in Escherichia coli K-12) NP_311718.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH NP_311719.1 similar to YGED_ECOLI gi|1789200 (conserved in Escherichia coli K-12) NP_311720.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 NP_311721.1 controls transcription of galETKM NP_311722.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding NP_311723.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase NP_311724.1 similar to YGEA_ECOLI gi|1789205 (conserved in Escherichia coli K-12) NP_311725.1 similar to ARAE_ECOLI gi|1789207 (conserved in Escherichia coli K-12) NP_311726.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate NP_311727.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate NP_311728.2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis NP_311729.1 similar to B2845_ECOLI gi|1789211 (conserved in Escherichia coli K-12) NP_311730.1 similar to YQEH_ECOLI gi|1789212 (conserved in Escherichia coli K-12) NP_311731.1 similar to YQEI_ECOLI gi|1789213 (conserved in Escherichia coli K-12) NP_311732.1 similar to YQEJ_ECOLI gi|2367166 (conserved in Escherichia coli K-12) NP_311733.2 similar to YQEK_ECOLI gi|2367167 (conserved in Escherichia coli K-12) NP_311734.1 similar to YGEF_ECOLI gi|2367169 (conserved in Escherichia coli K-12) NP_311735.1 similar to YGEG_ECOLI gi|1789215 (conserved in Escherichia coli K-12) NP_311736.1 similar to YGEH_ECOLI gi|1789216 (conserved in Escherichia coli K-12) NP_311737.1 similar to B2853_ECOLI gi|1789217 (conserved in Escherichia coli K-12) NP_311738.1 similar to B2854_ECOLI gi|1789218 (conserved in Escherichia coli K-12) NP_311739.1 similar to b2856_ECOLI gi|1789220, YGEK_ECOLI gi|1789219 NP_311740.1 similar to B2857_ECOLI gi|1789221 (conserved in Escherichia coli K-12) NP_311741.1 similar to B2858_ECOLI gi|1789222 (conserved in Escherichia coli K-12) NP_311742.1 similar to B2859_ECOLI gi|1789223 (conserved in Escherichia coli K-12) NP_311743.1 lipoprotein precursor (type III secretion system); similar to lipoprotein precursors in type III secretion system e.g. PrgK protein [Salmonella typhimurium] gi|1172615|sp|P41786|PRGK_SALTY; type III secretion system lipoprotein precursor NP_311744.1 similar to PrgJ [Salmonella typhimurium] gi|1172614|sp|P41785|PRGJ_SALTY, MxiI [Shigella flexneri] gi|547954|sp|Q06080|MXII_SHIFL; type III secretion protein NP_311745.1 similar to type III secretion proteins e.g. PrgI protein [Salmonella typhimurium] gi|1172613|sp|P41784|PRGI_SALTY NP_311746.1 similar to MxiG [Shigella flexneri] gi|2498603|sp|Q57332|MXIG_SHIFL, PrgH protein [Salmonella typhimurium] gi|1172612|sp|P41783|PRGH_SALTY; type III secretion protein NP_311747.1 similar to transcriptional activator NtrC [Herbaspirillum seropedicae] gi|57313501|gb|AAC32391.21 NP_311748.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins NP_311751.1 similar to type III secretion proteins e.g. SpaQ [Salmonella enterica] gi|975756|gb|AAC43847.1| NP_311752.1 part of a type III secretory system probably involved in invasion into eukaryotic cells NP_311753.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells NP_311754.1 similar to type III secretion proteins e.g. SpaN [Salmonella enterica] gi|1155289|gb|AAC44993.1 NP_311756.1 similar to type III secretion proteins e.g. SpaM [Salmonella enterica] gi|1155297|gb|AAC44998.1| NP_311757.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase NP_311758.1 similar to type III secretion proteins e.g. InvA [Salmonella typhimurium] gi|476819|pir||A42888 NP_311759.1 similar to type III secretion proteins e.g. invasion protein [Salmonella enterica] gi|1236845|gb|AAC45041.1| NP_311760.1 similar to type III secretion proteins e.g. InvG [Salmonella typhimurium] gi|1170574|sp|P35672|INVG_SALTY NP_311761.1 similar to transcriptional regulators e.g. invF [Salmonella typhimurium] gi|729852|sp|P39437|INVF_SALTY; transcriptional regulator of type III secretion system; type III secretion protein NP_311763.1 similar to B2863 gi|1789227 and B2862_ECOLI gi|1789226 NP_311764.1 similar to B2863_ECOLI gi|1789227 NP_311765.2 similar to B2865_ECOLI gi|1789228 (conserved in Escherichia coli K-12) NP_311766.1 molybdenum cofactor-binding protein; participates in purine salvage NP_311767.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage NP_311768.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage NP_311769.1 similar to YGEV_ECOLI gi|1789233 (conserved in Escherichia coli K-12) NP_311770.1 catalyzes the formation of L-citruline from L-ornithine and carbamoylphosphate NP_311771.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate NP_311772.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases NP_311773.2 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position NP_311774.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP NP_311775.1 similar to B2875_ECOLI gi|1789240 (conserved in Escherichia coli K-12) NP_311776.1 similar to B2876_ECOLI gi|1789241 (conserved in Escherichia coli K-12) NP_311777.1 similar to YGFJ_ECOLI gi|1789242 (conserved in Escherichia coli K-12) NP_311778.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase NP_311779.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS NP_311780.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain NP_311781.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration NP_311782.1 similar to YGFO_ECOLI gi|1789248 (conserved in Escherichia coli K-12) NP_311783.1 Catalyzes the deamination of guanine NP_311784.1 similar to YGFQ_ECOLI gi|1789250, YGFR_ECOLI gi|1789251 NP_311785.1 similar to YGFS_ECOLI gi|1789252 NP_311786.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) NP_311787.1 similar to YGFU_ECOLI gi|1789254 (conserved in Escherichia coli K-12) NP_311788.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate NP_311789.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_311790.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_311791.1 5'-3' single-stranded-DNA-specific exonuclease NP_311792.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity NP_311793.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_311794.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic NP_311795.1 similar to B2896_ECOLI gi|1789263 (conserved in Escherichia coli K-12) NP_311796.1 similar to YGFY_ECOLI gi|1789264 (conserved in Escherichia coli K-12) NP_311797.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator NP_311798.1 similar to B2899_ECOLI gi|1789266 (conserved in Escherichia coli K-12) NP_311799.1 similar to YQFB_ECOLI gi|1789267 (conserved in Escherichia coli K-12) NP_311800.1 similar to BGLA_ECOLI gi|2367174 (conserved in Escherichia coli K-12) NP_311801.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine NP_311802.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_311803.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein NP_311804.1 similar to VISC_ECOLI gi|1789273 (conserved in Escherichia coli K-12) NP_311805.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone NP_311806.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide NP_311807.3 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown NP_311808.1 similar to YGFE_ECOLI gi|1789277 (conserved in Escherichia coli K-12) NP_311809.3 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function NP_311811.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate NP_311812.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway NP_311813.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport NP_311814.1 MDM; functions in conversion of succinate to propionate NP_311815.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins NP_311816.2 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA NP_311817.1 similar to YGFH_ECOLI gi|1789287 (conserved in Escherichia coli K-12) NP_311820.1 similar to YGGE_ECOLI gi|1789289 (conserved in Escherichia coli K-12) NP_311821.1 Involved in the export of arginine NP_311822.1 participates in the regulation of osmotic pressure changes within the cel NP_311823.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate NP_311824.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_311825.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate NP_311826.1 similar to hypothetical protein [Methanobacterium thermoautotrophicum] gi|7482365|pir||D69031 NP_311827.1 similar to probable low-affinity inorganic phosphate transporter [Mycobacterium tuberculosis] gi|7387993|sp|O06411|PIT_MYCTU, hypothetical protein [Plasmid pNZ4000] gi|5123516|gb|AAD40355.1| NP_311828.1 similar to hypothetical protein [Plasmid pNZ4000] gi|5123517|gb|AAD40356.1| NP_311829.1 similar to ABC transporter ATP-binding proteins e.g. cation ABC transporter (ATP-binding protein) homolog ykoD [Bacillus subtilis] gi|7445788|pir||H69858 NP_311830.1 similar to ABC transporter ATP-binding proteins e.g. PotA homolog [Agrobacterium rhizogenes plasmid pRi1724] gi|8918682|dbj|BAA97747.1|, [plasmid pNZ4000] gi|512351 NP_311831.1 similar to YGGC_ECOLI gi|1789296, kinase-like protein FrcK [Sinorhizobium meliloti] dad|AF196574-5|AAG28501.1 NP_311832.1 similar to YGGD_ECOLI gi|1789297 (conserved in Escherichia coli K-12) NP_311833.1 similar to YGGF_ECOLI gi|1789298 (conserved in Escherichia coli K-12) NP_311834.1 similar to YGGP_ECOLI gi|1789300, B2931_ECOLI similar to gi|1789299 NP_311835.1 similar to CMTA_ECOLI gi|1789301 (conserved in Escherichia coli K-12) NP_311836.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein NP_311837.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_311838.2 similar to YGGG_ECOLI gi|1789305 (conserved in Escherichia coli K-12) NP_311839.1 catalyzes the formation of putrescine from agmatine NP_311841.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis NP_311842.1 similar to YQGB_ECOLI gi|1789308 (conserved in Escherichia coli K-12) NP_311843.1 similar to YQGC_ECOLI gi|1789309 (conserved in Escherichia coli K-12) NP_311844.1 similar to YQGD_ECOLI gi|1789310 (conserved in Escherichia coli K-12) NP_311845.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase NP_311846.1 similar to GALP_ECOLI gi|1789312 (conserved in Escherichia coli K-12) NP_311847.1 similar to SPRT_ECOLI gi|1789313 (conserved in Escherichia coli K-12) NP_311848.1 similar to ENDA_ECOLI gi|1789314 (conserved in Escherichia coli K-12) NP_311849.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase NP_311850.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione NP_311851.2 similar to YQGE_ECOLI gi|1789317 (conserved in Escherichia coli K-12) NP_311852.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_311853.1 similar to YGGR_ECOLI gi|1789320 (conserved in Escherichia coli K-12) NP_311854.1 similar to YGGS_ECOLI gi|1789321 (conserved in Escherichia coli K-12) NP_311855.1 similar to YGGT_ECOLI gi|1789322 (conserved in Escherichia coli K-12) NP_311856.2 similar to YGGU_ECOLI gi|1789323 (conserved in Escherichia coli K-12) NP_311857.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_311858.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_311859.1 similar to YGGM_ECOLI gi|1789326 (conserved in Escherichia coli K-12) NP_311860.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis NP_311861.1 similar to YGGN_ECOLI gi|1789328 (conserved in Escherichia coli K-12) NP_311862.2 similar to YGGL_ECOLI gi|1789329 (conserved in Escherichia coli K-12) NP_311863.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_311864.1 similar to MUTY_ECOLI gi|1789331 (conserved in Escherichia coli K-12) NP_311865.1 similar to YGGX_ECOLI gi|1789332 (conserved in Escherichia coli K-12) NP_311866.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues NP_311867.2 transport of nucleosides; permease; similar to NUPG_ECOLI gi|1789336 (conserved in Escherichia coli K-12) NP_311868.2 similar to SPEC_ECOLI gi|1789337 (conserved in Escherichia coli K-12) NP_311869.1 similar to YQGA_ECOLI gi|1789338 (conserved in Escherichia coli K-12) NP_311870.1 similar to integrases e.g. [prophage P4] gi|6179516|emb|CAB59974.1 NP_311873.1 similar to hypothetical proteins e.g. ORF29 [Escherichia coli plasmid pB171] gi|6009405|dbj|BAA84864.1 NP_311874.1 similar to hypothetical proteins e.g. ORF30 [Escherichia coli plasmid pB171] gi|6009406|dbj|BAA84865.1 NP_311875.1 similar to hypothetical proteins e.g. ORF31 [Escherichia coli plasmid pB171] gi|6009427|dbj|BAA84886.1 NP_311876.1 similar to hypothetical protein [Salmonella choleraesuis] gi|7467227|pir||T28668 NP_311877.1 similar to virulence-related membrane proteins e.g. pagC [Salmonella typhimurium] gi|129558|sp|P23988|PAGC_SALTY NP_311879.1 similar to hypothetical proteins e.g. FhaB [Neisseria meningitidis] gi|6900333|emb|CAB71945.1| NP_311881.1 similar to KfaE [Escherichia coli] gi|628752|pir||S45104 NP_311882.1 similar to ShET2 enterotoxin [Shigella flexneri] gi|1109754|emb|CAA90938.1|, hypothetical proteins e.g. ankyrilike regulatory protein [Escherichia coli] gi|418526|sp|P2 NP_311884.1 similar to hypothetical protein [Salmonella typhimurium] gi|6960367|gb|AAF33527.1 NP_311886.1 similar to hypothetical proteins in insertion elements e.g. [IS630] gi|140943|sp|P16943|YIS5_SHISO NP_311889.1 OrfB protein of insertion sequence IS629; similar to transposase [Escherichia coli plasmid pO157 IS629] gi|7443862|pir||T00240 NP_311890.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein [Escherichia coli plasmid pO157 IS629] gi|7444868|pir||T00241, hypothetical proteins in insertion sequences e.g. [Shigella flexneri] gi|5532454|gb|AAD44738.1|AF141323_9 NP_311892.1 similar to hypothetical proteins e.g. L0014 [Escherichia coli O157:H7 strain EDL933] gi|3414882|gb|AAC31493.1| NP_311893.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1| NP_311895.1 similar to hypothetical proteins e.g. ORF50 [Escherichia coli plasmid pB171] gi|6009426|dbj|BAA84885.1| NP_311896.1 similar to hypothetical proteins e.g. L0015 [Escherichia coli O157:H7 strain EDL933] gi|3414883|gb|AAC31494.1| NP_311898.1 similar to hypothetical proteins e.g. L0004 [Escherichia coli O157:H7 strain EDL933] gi|3414872|gb|AAC31483.1|, transposase [Vibrio cholerae] gi|7960026|gb|AAF71186.1|AF179596_6 NP_311899.1 similar to PITB_ECOLI gi|1789360 NP_311900.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction NP_311901.2 YghU; B2989; one of eight glutathione transferases from E. coli NP_311902.1 similar to HYBG_ECOLI gi|1789364 (conserved in Escherichia coli K-12) NP_311903.1 plays a role in hydrogenase nickel cofactor insertion NP_311904.1 similar to HYBE_ECOLI gi|1789366 (conserved in Escherichia coli K-12) NP_311905.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) NP_311906.1 involved in hydrogen uptake NP_311907.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits NP_311908.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 NP_311909.1 involved in hydrogen uptake NP_311910.1 similar to B2998_ECOLI gi|1789372 (conserved in Escherichia coli K-12) NP_311911.1 similar to B3000_ECOLI gi|1789374, B2999_ECOLI gi|1789373 NP_311912.1 similar to B3001_ECOLI gi|1789375 (conserved in Escherichia coli K-12) NP_311913.1 similar to YQHA_ECOLI gi|1789376 (conserved in Escherichia coli K-12) NP_311914.1 similar to YGHA_ECOLI gi|1789378 (conserved in Escherichia coli K-12) NP_311915.1 similar to B3004_ECOLI gi|1789379 (conserved in Escherichia coli K-12) NP_311916.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell NP_311917.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell NP_311918.1 similar to B3007_ECOLI gi|1789382 (conserved in Escherichia coli K-12) NP_311919.1 catalyzes the formation of L-homocysteine from cystathionine NP_311920.1 similar to YGHB_ECOLI gi|1789384 (conserved in Escherichia coli K-12) NP_311921.2 similar to YQHC_ECOLI gi|1789385 (conserved in Escherichia coli K-12) NP_311922.1 similar to YQHD_ECOLI gi|1789386 (conserved in Escherichia coli K-12) NP_311923.2 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate NP_311924.1 similar to N-terminal part of YQHG_ECOLI gi|2367185 NP_311925.1 similar to C-terminal part of YQHG_ECOLI gi|2367185 NP_311926.1 similar to YQHH_ECOLI gi|1789390 (conserved in Escherichia coli K-12) NP_311927.1 similar to YGIR_ECOLI similar to gi|1789392, B3015_ECOLI gi|1789391 NP_311928.1 similar to SUFI_ECOLI gi|1789394 (conserved in Escherichia coli K-12) NP_311929.1 similar to PLSC_ECOLI gi|1789395 (conserved in Escherichia coli K-12) NP_311930.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_311931.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system NP_311932.1 similar to B3023_ECOLI gi|1789400 (conserved in Escherichia coli K-12) NP_311933.1 similar to YGIW_ECOLI gi|1789401 (conserved in Escherichia coli K-12) NP_311934.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes NP_311937.1 similar to MDAB_ECOLI gi|1789406 (conserved in Escherichia coli K-12) NP_311938.1 similar to YGIN_ECOLI gi|1789407 (conserved in Escherichia coli K-12) NP_311939.1 similar to regulators (RpiR family) e.g. [Bacillus subtilis] gi|8248807|emb|CAB93068.1 NP_311940.1 similar to ferrichrome-binding proteins e.g. [Bacillus subtilis] gi|585132|sp|P37580|FHUD_BACSU NP_311941.1 similar to ferrichrome ABC transporter (permease) e.g. [Bacillus subtilis] gi|1706797|sp|P49937|FHUG_BACSU NP_311942.1 similar to ferrichrome ABC transporters (permease) e.g. [Synechocystis sp.] gi|7442493|pir||S74438, [Bacillus subtilis] gi|1706795|sp|P49936|FHUB_BACSU NP_311943.1 similar to ABC-type iron-siderophore transport system ATP-binding proteins e.g. [Synechocystis sp.] gi|7442509|pir||S74440 NP_311944.1 similar to ferrichrome-iron receptor precursors e.g. gi|7448497|pir||S74457 NP_311945.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_311946.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate NP_311947.1 similar to ICC_ECOLI gi|1789410 (conserved in Escherichia coli K-12) NP_311948.1 similar to YQIB_ECOLI gi|1789411 (conserved in Escherichia coli K-12) NP_311949.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose NP_311950.2 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell NP_311951.1 similar to YGIA_ECOLI gi|1789414 (conserved in Escherichia coli K-12) NP_311952.2 similar to YGIB_ECOLI gi|1789415 (conserved in Escherichia coli K-12) NP_311953.1 similar to YGIC_ECOLI gi|1789416 (conserved in Escherichia coli K-12) NP_311954.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine NP_311955.1 similar to YGIE_ECOLI gi|1789419 (conserved in Escherichia coli K-12) NP_311956.1 DHBP synthase; functions during riboflavin biosynthesis NP_311957.2 similar to B3042_ECOLI gi|1789421 (conserved in Escherichia coli K-12) NP_311958.1 Involved in glycogen synthesis. May be involved in glycogen priming NP_311959.1 similar to B3050_ECOLI gi|1789429 (conserved in Escherichia coli K-12) NP_311960.1 similar to B3051_ECOLI gi|1789430 (conserved in Escherichia coli K-12) NP_311962.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose NP_311963.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme NP_311964.1 similar to YGIF_ECOLI gi|1789434 (conserved in Escherichia coli K-12) NP_311965.1 similar to YGIM_ECOLI gi|1789435 (conserved in Escherichia coli K-12) NP_311966.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases NP_311967.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell NP_311968.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin NP_311969.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX NP_311970.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol NP_311971.1 Involved in the tartrate degradation pathway NP_311972.1 Involved in the tartrate degradation pathway NP_311973.1 similar to YGJE_ECOLI gi|1789444 (conserved in Escherichia coli K-12) NP_311974.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_311975.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_311976.1 synthesizes RNA primers at the replication forks NP_311977.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria NP_311978.1 similar to YGJF_ECOLI gi|1789449 (conserved in Escherichia coli K-12) NP_311979.1 similar to YQJH_ECOLI gi|1789450 (conserved in Escherichia coli K-12) NP_311980.1 similar to YQJI_ECOLI gi|1789452 (conserved in Escherichia coli K-12) NP_311981.1 similar to AER_ECOLI gi|1789453 (conserved in Escherichia coli K-12) NP_311982.2 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate NP_311983.1 similar to YGJH_ECOLI gi|1789455 (conserved in Escherichia coli K-12) NP_311984.1 similar to EBGR_ECOLI gi|1789456 (conserved in Escherichia coli K-12) NP_311985.2 in Escherichia coli this is the second beta-galactosidase system NP_311986.1 in Escherichia coli this is the second beta-galactosidase system NP_311987.1 similar to YGJI_ECOLI gi|1789459 (conserved in Escherichia coli K-12) NP_311988.1 similar to YGJJ_ECOLI gi|1789461 (conserved in Escherichia coli K-12) NP_311989.1 similar to YGJK_ECOLI gi|1789462 (conserved in Escherichia coli K-12) NP_311990.1 similar to YGJL_ECOLI gi|1789463 (conserved in Escherichia coli K-12) NP_311991.1 similar to YGJM_ECOLI gi|1789464 (conserved in Escherichia coli K-12) NP_311992.1 similar to YGJN_ECOLI gi|1789465 (conserved in Escherichia coli K-12) NP_311993.2 similar to YGJO_ECOLI gi|1789466 (conserved in Escherichia coli K-12) NP_311994.1 similar to YGJP_ECOLI gi|1789467 (conserved in Escherichia coli K-12) NP_311995.1 similar to YGJQ_ECOLI gi|1789468 (conserved in Escherichia coli K-12) NP_311996.1 similar to YGJR_ECOLI gi|2367190 (conserved in Escherichia coli K-12) NP_311997.1 similar to YGJT_ECOLI gi|1789472 (conserved in Escherichia coli K-12) NP_311998.1 involved in the import of serine and threonine coupled with the import of sodium NP_311999.1 similar to YGJV_ECOLI gi|1789474 (conserved in Escherichia coli K-12) NP_312000.1 similar to UXAA_ECOLI gi|1789475 (conserved in Escherichia coli K-12) NP_312001.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism NP_312002.1 similar to EXUT_ECOLI gi|2367193 (conserved in Escherichia coli K-12) NP_312003.2 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. NP_312004.1 similar to YQJA_ECOLI gi|1789481 (conserved in Escherichia coli K-12) NP_312005.1 similar to YQJB_ECOLI gi|1789482 (conserved in Escherichia coli K-12) NP_312006.2 similar to YQJC_ECOLI gi|2367195 (Conserved in E.coli K-q2) NP_312007.1 similar to YQJD_ECOLI gi|1789485 (conserved in Escherichia coli K-12) NP_312008.1 similar to YQJE_ECOLI gi|1789486 (conserved in Escherichia coli K-12) NP_312009.1 similar to B3100_ECOLI gi|1789487 (conserved in Escherichia coli K-12) NP_312010.1 similar to YQJF_ECOLI gi|1789488 (conserved in Escherichia coli K-12) NP_312011.1 similar to YQJG_ECOLI gi|1789489 (conserved in Escherichia coli K-12) NP_312012.1 similar to YHAH_ECOLI gi|2367196 (conserved in Escherichia coli K-12) NP_312013.1 similar to YHAI_ECOLI gi|1789491 (conserved in Escherichia coli K-12) NP_312014.1 similar to YHAJ_ECOLI gi|1789492 (conserved in Escherichia coli K-12) NP_312015.1 similar to YHAK_ECOLI gi|1789493 (conserved in Escherichia coli K-12) NP_312016.1 similar to YHAL_ECOLI gi|1789494 (conserved in Escherichia coli K-12) NP_312017.1 similar to YHAN_ECOLI gi|1789496, YHAM_ECOLI gi|1789495 NP_312018.1 similar to YHAO_ECOLI gi|1789497 (conserved in Escherichia coli K-12) NP_312019.1 similar to YHAQ_ECOLI gi|1789500, YHAP_ECOLI gi|1789498, L-serine deaminase gi|1788116 NP_312020.2 similar to YHAR_ECOLI gi|1789501 (conserved in Escherichia coli K-12) NP_312021.1 similar to TDCE_ECOLI gi|1789502 (conserved in Escherichia coli K-12) NP_312022.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism NP_312023.1 involved in the import of threonine and serine in combination with the import of a proton NP_312024.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic NP_312025.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation NP_312026.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon NP_312027.1 similar to YHAB_ECOLI gi|1789508 (conserved in Escherichia coli K-12) NP_312028.1 similar to YHAC_ECOLI gi|1789509 (conserved in Escherichia coli K-12) NP_312029.2 similar to YHAD_ECOLI gi|1789512 (conserved in Escherichia coli K-12) NP_312030.2 catalyzes the reduction of tartronate semialdehyde to glycerate NP_312031.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate NP_312032.1 similar to YHAU_ECOLI gi|1789515 (conserved in Escherichia coli K-12) NP_312033.1 similar to YHAG_ECOLI gi|1789516 (conserved in Escherichia coli K-12) NP_312034.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation NP_312035.1 similar to YHAV_ECOLI gi|1789518 (conserved in Escherichia coli K-12) NP_312036.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons NP_312037.1 similar to KBAZ_ECOLI (strain C) dad|AF228498-2|AAF81082.1 (conserved in Escherichia coli K-12) NP_312038.2 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport NP_312039.1 similar to AGAW_ECOLI (strain C) gi|8895748|gb|AAF81084.1|AF228498_4 NP_312040.1 AgaE; similar to PTS dependent N-acetyl-galactosamine-IID component, AgaE [Escherichia coli strain C] gi|8895749|gb|AAF81085.1|AF228498_5 NP_312041.1 AfaF; similar to ts dependent N-acetyl-galactosamine- and galactosamine IIA component, AgaF [Escherichia coli strain C] gi|8895750|gb|AAF81086.1|AF228498_6 NP_312042.1 similar to AGAA_ECOLI (strain C) gi|8895751|dad|AF228498-7|AAF81087.1 NP_312043.1 similar to AGAS_ECOLI (strain C) dad|AF228498-8|AAF81088.1 (conserved in Escherichia coli K-12) NP_312044.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway NP_312045.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport NP_312046.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport NP_312047.1 similar to YRAH_ECOLI gi|1789531 (conserved in Escherichia coli K-12) NP_312048.1 similar to YRAI_ECOLI gi|1789532 (conserved in Escherichia coli K-12) NP_312049.1 similar to YRAJ_ECOLI gi|1789533 (conserved in Escherichia coli K-12) NP_312050.1 similar to fimbrial protein YRAK_ECOLI gi|1789534 NP_312051.1 OrfA protein of insertion sequence IS629; similar to hypothetical protein gi|7444868|pir||T00241 NP_312052.1 OrfB protein of insertion sequence IS629; similar to gi|7443862|pir||T00240 NP_312053.1 similar to YRAK_ECOLI gi|1789534 NP_312054.1 similar to YRAL_ECOLI gi|1789535 (conserved in Escherichia coli K-12) NP_312055.1 similar to YRAM_ECOLI gi|1789537 (conserved in Escherichia coli K-12) NP_312056.1 similar to YRAN_ECOLI gi|1789538 (conserved in Escherichia coli K-12) NP_312057.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein NP_312058.1 similar to YRAP_ECOLI gi|1789540 (conserved in Escherichia coli K-12) NP_312059.1 similar to YRAQ_ECOLI gi|1789541 (conserved in Escherichia coli K-12) NP_312060.1 similar to YRAR_ECOLI gi|1789542 (conserved in Escherichia coli K-12) NP_312061.1 similar to YHBO_ECOLI gi|1789543 (conserved in Escherichia coli K-12) NP_312062.1 similar to YHBP_ECOLI gi|1789544 (conserved in Escherichia coli K-12) NP_312063.1 similar to YHBQ_ECOLI gi|1789545 (conserved in Escherichia coli K-12) NP_312064.1 similar to YHBS_ECOLI gi|1789546 (conserved in Escherichia coli K-12) NP_312065.1 similar to YHBT_ECOLI gi|1789547 (conserved in Escherichia coli K-12) NP_312066.1 similar to YHBU_ECOLI gi|1789548 (conserved in Escherichia coli K-12) NP_312067.1 similar to YHBV_ECOLI gi|1789549 (conserved in Escherichia coli K-12) NP_312068.1 similar to YHBW_ECOLI gi|1789551 (conserved in Escherichia coli K-12) NP_312069.1 tryptophan transporter of high affinity NP_312070.2 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division NP_312071.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing NP_312072.1 similar to PNP_ECOLI gi|1789555 (conserved in Escherichia coli K-12) NP_312073.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_312074.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs NP_312075.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_312076.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_312077.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_312078.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins NP_312079.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis NP_312080.1 similar to YHBX_ECOLI gi|1789564 (conserved in Escherichia coli K-12) NP_312081.1 protein-export protein; similar to SECG_ECOLI gi|1789565 (conserved in Escherichia coli K-12) NP_312082.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_312083.2 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate NP_312084.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins NP_312085.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit NP_312086.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability NP_312087.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_312088.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains NP_312089.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_312090.1 similar to YHBE_ECOLI gi|1789575 (conserved in Escherichia coli K-12) NP_312091.1 involved in the peptidyltransferase reaction during translation NP_312092.1 similar to RPLU_ECOLI gi|1789577 (conserved in Escherichia coli K-12) NP_312093.1 similar to ISPB_ECOLI gi|1789578 (conserved in Escherichia coli K-12) NP_312094.1 activator of maltose metabolism genes NP_312095.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_312096.1 similar to YRBA_ECOLI gi|1789581 (conserved in Escherichia coli K-12) NP_312097.2 similar to YRBB_ECOLI gi|1789582 (conserved in Escherichia coli K-12) NP_312098.1 similar to YRBC_ECOLI gi|1789583 (conserved in Escherichia coli K-12) NP_312099.1 similar to YRBD_ECOLI gi|1789584 (conserved in Escherichia coli K-12) NP_312100.1 similar to YRBE_ECOLI gi|1789585 (conserved in Escherichia coli K-12) NP_312101.1 ATP-binding protein of a ABC toluene efflux transporter NP_312102.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers NP_312103.1 similar to YRBH_ECOLI gi|1789588 (conserved in Escherichia coli K-12) NP_312104.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis NP_312105.1 similar to YRBK_ECOLI gi|1789591 (conserved in Escherichia coli K-12) NP_312106.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system NP_312107.1 similar to YHBG_ECOLI gi|1789593 (conserved in Escherichia coli K-12) NP_312108.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen NP_312109.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing NP_312110.1 similar to PTSN_ECOLI gi|1789597 (conserved in Escherichia coli K-12) NP_312111.1 similar to YHBJ_ECOLI gi|1789598 (conserved in Escherichia coli K-12) NP_312112.1 similar to PTSO_ECOLI gi|1789599 (conserved in Escherichia coli K-12) NP_312113.1 similar to YRBL_ECOLI gi|1789600 (conserved in Escherichia coli K-12) NP_312114.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan NP_312115.2 similar to YHBL_ECOLI gi|1789602 (conserved in Escherichia coli K-12) NP_312116.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA NP_312117.1 similar to YHCC_ECOLI gi|2367204 (conserved in Escherichia coli K-12) NP_312118.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate NP_312119.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate NP_312120.1 similar to YHCG_ECOLI gi|1789614 (conserved in Escherichia coli K-12) NP_312121.1 similar to YHCH_ECOLI gi|1789615 (conserved in Escherichia coli K-12) NP_312122.2 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein NP_312123.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate NP_312124.2 similar to NANT_ECOLI gi|1789618 (conserved in Escherichia coli K-12) NP_312125.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid NP_312126.2 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization NP_312127.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic NP_312128.1 similar to SSPB_ECOLI gi|1789623 (conserved in Escherichia coli K-12) NP_312129.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation NP_312130.1 forms a direct contact with the tRNA during translation NP_312131.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_312132.1 similar to YHCM_ECOLI gi|1789627 (conserved in Escherichia coli K-12) NP_312133.1 similar to YHCB_ECOLI gi|1789628 (conserved in Escherichia coli K-12) NP_312134.1 similar to DEGQ_ECOLI gi|1789629 (conserved in Escherichia coli K-12) NP_312135.1 similar to DEGS_ECOLI gi|1789630 (conserved in Escherichia coli K-12) NP_312136.1 oxidizes malate to oxaloacetate NP_312137.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes NP_312138.1 similar to YHCN_ECOLI gi|1789634 (conserved in Escherichia coli K-12) NP_312139.1 similar to YHCO_ECOLI gi|1789635 (conserved in Escherichia coli K-12) NP_312140.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate NP_312141.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate NP_312142.2 membrane protein AaeX; the gene is a member of the aaeXAB operon NP_312143.1 similar to YHCS_ECOLI gi|1789639 (conserved in Escherichia coli K-12) NP_312144.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA NP_312145.1 similar to YHDR_ECOLI gi|1789643, YHDP_ECOLI similar to gi|2367206 NP_312146.1 involved in the processing of the 5'end of 16S rRNA NP_312147.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_312148.1 part of cell wall structural complex MreBCD; transmembrane component NP_312149.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_312150.2 functions in MreBCD complex in some organisms NP_312151.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules NP_312152.1 similar to YHDH_ECOLI gi|1789651 (conserved in Escherichia coli K-12) NP_312154.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_312155.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_312156.1 similar to YHDT_ECOLI gi|1789655 (conserved in Escherichia coli K-12) NP_312157.2 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase NP_312158.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype NP_312159.1 similar to YHDG_ECOLI gi|1789660 (conserved in Escherichia coli K-12) NP_312160.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription NP_312161.2 similar to YHDJ_ECOLI gi|1789662 (conserved in Escherichia coli K-12) NP_312162.1 similar to YHAU_ECOLI gi|1789515 (conserved in Escherichia coli K-12) NP_312163.1 similar to ENVR_ECOLI gi|1789664 (conserved in Escherichia coli K-12) NP_312164.1 similar to ACRE_ECOLI gi|1789665 (conserved in Escherichia coli K-12) NP_312167.1 similar to YHAV_ECOLI gi|1789518 (conserved in Escherichia coli K-12) NP_312168.2 similar to YHDW_ECOLI gi|1789668 (conserved in Escherichia coli K-12) NP_312169.2 similar to YHDX_ECOLI gi|1789669 (conserved in Escherichia coli K-12) NP_312170.1 similar to YHDY_ECOLI gi|1789671 (conserved in Escherichia coli K-12) NP_312171.1 similar to YHDZ_ECOLI gi|1789672 (conserved in Escherichia coli K-12) NP_312172.1 similar to YRDA_ECOLI gi|1789673 (conserved in Escherichia coli K-12) NP_312173.1 similar to YRDB_ECOLI gi|1789674 (conserved in Escherichia coli K-12) NP_312174.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate NP_312175.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA NP_312176.1 similar to YRDD_ECOLI gi|1789677 NP_312177.1 similar to SMG_ECOLI gi|1789679 (conserved in Escherichia coli K-12) NP_312178.1 similar to SMF_ECOLI Sp|P30852 (conserved in Escherichia coli K-12) NP_312179.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_312180.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_312181.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase NP_312182.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain NP_312183.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock NP_312184.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators NP_312185.1 similar to YHDN_ECOLI gi|1789688 (conserved in Escherichia coli K-12) NP_312186.1 is a component of the macrolide binding site in the peptidyl transferase center NP_312187.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_312188.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_312189.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_312190.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_312191.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif NP_312192.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_312193.1 late assembly protein NP_312194.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 NP_312195.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_312196.1 binds 5S rRNA along with protein L5 and L25 NP_312197.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_312198.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_312199.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_312200.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_312201.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_312202.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_312203.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_312204.1 one of the stabilizing components for the large ribosomal subunit NP_312205.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_312206.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_312207.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_312208.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_312209.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_312210.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_312211.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_312212.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_312213.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_312215.1 similar to leader peptidases e.g. HopD (strain ECOR30) [Escherichia coli] gi|7674073|sp|O68932, (LT2) [Salmonella typhimurium] gi|7674072|sp|O68927 NP_312216.1 iron storage protein NP_312217.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_312218.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_312219.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_312220.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_312221.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs NP_312222.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs NP_312223.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs NP_312224.2 similar to YHEO_ECOLI gi|1789744 (conserved in Escherichia coli K-12) NP_312225.1 rotamase NP_312226.1 similar to SLYX_ECOLI gi|1789747 (conserved in Escherichia coli K-12) NP_312227.1 rotamase NP_312228.1 involved in potassium efflux NP_312229.1 required for KefB activity NP_312230.1 similar to YHES_ECOLI gi|1789751 (conserved in Escherichia coli K-12) NP_312231.1 similar to YHET_ECOLI gi|1789752 (conserved in Escherichia coli K-12) NP_312232.1 similar to YHEU_ECOLI gi|1789753 (conserved in Escherichia coli K-12) NP_312233.1 similar to PRKB_ECOLI gi|2367214 (conserved in Escherichia coli K-12) NP_312234.1 similar to YHFA_ECOLI gi|1789755 (conserved in Escherichia coli K-12) NP_312235.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons NP_312236.1 similar to YHFK_ECOLI gi|1789757 (conserved in Escherichia coli K-12) NP_312237.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate NP_312238.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity NP_312239.1 induced in stationary phase; recognized by rpoS; affects cell division; similar to FIC_ECOLI gi|1789761 (conserved in Escherichia coli K-12) NP_312240.1 similar to YHFG_ECOLI gi|1789762 (conserved in Escherichia coli K-12) NP_312241.1 similar to PPIA_ECOLI gi|1789763 (conserved in Escherichia coli K-12) NP_312242.1 similar to YHFC_ECOLI gi|1789764 (conserved in Escherichia coli K-12) NP_312243.1 similar to NIRB_ECOLI gi|1789765 (conserved in Escherichia coli K-12) NP_312244.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations NP_312245.2 member of the FNT family of formate and nitrite transporters NP_312246.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin NP_312247.1 similar to YHFL_ECOLI gi|1789770 (conserved in Escherichia coli K-12) NP_312248.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon NP_312249.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine NP_312250.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine NP_312251.1 similar to YHFQ_ECOLI gi|1789775 (conserved in Escherichia coli K-12) NP_312252.3 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes NP_312253.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_312254.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate NP_312255.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_312256.1 similar to DAM_ECOLI gi|1789789 (conserved in Escherichia coli K-12) NP_312257.1 membrane protein ; similar to DAMX_ECOLI gi|1789790 (conserved in Escherichia coli K-12) NP_312258.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_312259.2 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_312260.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa NP_312261.2 similar to YRFA_ECOLI gi|1789794 (conserved in Escherichia coli K-12) NP_312262.1 similar to YRFB_ECOLI gi|1789795 (conserved in Escherichia coli K-12) NP_312263.1 similar to YRFC_ECOLI gi|1789796 (conserved in Escherichia coli K-12) NP_312264.1 similar to YRFD_ECOLI gi|1789797 (conserved in Escherichia coli K-12) NP_312265.2 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits NP_312266.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose NP_312267.1 similar to YRFF_ECOLI gi|1789801 (conserved in Escherichia coli K-12) NP_312268.2 similar to YRFG_ECOLI gi|1789802 (conserved in Escherichia coli K-12) NP_312269.1 similar to HSLR_ECOLI gi|1176866|sp|P45802 (conserved in Escherichia coli K-12) NP_312270.3 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers NP_312271.1 similar to YHGE_ECOLI gi|1789805 (conserved in Escherichia coli K-12) NP_312272.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP NP_312273.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR NP_312274.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation NP_312275.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus NP_312276.1 similar to YHGF_ECOLI gi|1789811 (conserved in Escherichia coli K-12) NP_312277.1 similar to FEOA_ECOLI gi|1789812 (conserved in Escherichia coli K-12) NP_312278.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake NP_312279.1 similar to YHGG_ECOLI gi|1789814 (conserved in Escherichia coli K-12) NP_312280.1 similar to YHGA_ECOLI gi|1789816 (conserved in Escherichia coli K-12) NP_312281.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis NP_312282.2 involved in high-affinity gluconate transport NP_312283.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source NP_312284.1 similar to GNTT_ECOLI gi|1789820 (conserved in Escherichia coli K-12) NP_312285.1 amylomaltase; acts to release glucose from maltodextrins NP_312286.1 similar to MALP_ECOLI gi|2367221 (conserved in Escherichia coli K-12) NP_312287.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides NP_312288.1 similar to hypothetical protein [Xylella fastidiosa] gi|9112262|gb|AAF85593.1|AE003851_24 NP_312289.1 similar to hypothetical protein [Xylella fastidiosa] gi|9112263|gb|AAF85594.1|AE003851_25 NP_312290.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester NP_312291.1 similar to RTCB_ECOLI gi|2367224 (conserved in Escherichia coli K-12) NP_312292.1 similar to RTCR_ECOLI gi|1789828 (conserved in Escherichia coli K-12) NP_312293.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism NP_312294.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity NP_312295.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine NP_312296.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane NP_312298.1 similar to binding proteins e.g. phosphate-binding protein PstS homolog [Methanobacterium thermoautotrophicum (strain Delta H)] gi|7442891|pir||A69098 NP_312299.1 similar to YZGL_ECOLI gi|1789834, phosphate-binding proteins PstS homolog NP_312300.1 similar to GLGP_ECOLI gi|2367228 (conserved in Escherichia coli K-12) NP_312301.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose NP_312302.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate NP_312303.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen NP_312304.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_312305.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde NP_312306.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) NP_312307.1 similar to DNA processing chain A (Smf protein), e.g. [Neisseria meningitidis] gi|7378929|emb|CAB83472.1| NP_312312.1 similar to GNTU_1_ECOLI gi|1789844, GNTU_ECOLI SW: P46858 NP_312313.2 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate NP_312314.1 similar to GNTR_ECOLI gi|1789846 (conserved in Escherichia coli K-12) NP_312315.1 similar to YHHW_ECOLI gi|1789847 (conserved in Escherichia coli K-12) NP_312316.1 similar to YHHX_ECOLI gi|1789848 (conserved in Escherichia coli K-12) NP_312317.1 YhhY; regulated by the fur regulator; unknown function NP_312320.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides NP_312321.1 similar to YHHA_ECOLI gi|1789857 (conserved in Escherichia coli K-12) NP_312322.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate NP_312323.2 part of the UgpABCE glycerol-3-phosphate uptake system NP_312324.1 with UgpABC is involved in uptake of glycerol-3-phosphate NP_312325.1 with UgpEC is involved in the uptake of glycerol-3-phosphate NP_312326.1 with UgpACE is involved in the uptake of glycerol-3-phosphate NP_312328.2 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine NP_312329.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine NP_312330.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine NP_312331.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter NP_312332.1 similar to LIVJ_ECOLI gi|1789870 (conserved in Escherichia coli K-12) NP_312333.1 similar to YHHK_ECOLI gi|1789869 (conserved in Escherichia coli K-12) NP_312334.1 similar to hypothetical protein ORF79 [Escherichia coli plasmid pB171] gi|6009455|dbj|BAA84914.1 NP_312335.1 similar to hypothetical protein ORF80 [Escherichia coli plasmid pB171] NP_312336.1 similar to LIVJ_ECOLI gi|1789870 (conserved in Escherichia coli K-12) NP_312337.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters NP_312338.1 ABC transporter, membrane protein NP_312339.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions NP_312340.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins NP_312341.1 catalyzes the methylation of 16S rRNA at position G966 NP_312342.1 similar to YHHL_ECOLI gi|1789876 (conserved in Escherichia coli K-12) NP_312343.1 similar to YHHM_ECOLI gi|1789877 (conserved in Escherichia coli K-12) NP_312344.1 similar to YHHN_ECOLI gi|1789878 (conserved in Escherichia coli K-12) NP_312345.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury NP_312346.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs NP_312347.1 similar to YHHQ_ECOLI gi|1789882 (conserved in Escherichia coli K-12) NP_312348.3 similar to B3472_ECOLI gi|1789883 (conserved in Escherichia coli K-12) NP_312349.2 similar to YHHS_ECOLI gi|1789884 (conserved in Escherichia coli K-12) NP_312350.2 similar to YHHT_ECOLI gi|1789885 (conserved in Escherichia coli K-12) NP_312352.1 similar to O-methyltransferases e.g. acetylserotonin N-methyltransferase (EC 2.1.1.4) - chicken gi|2498445|sp|Q92056|HIOM_CHICK NP_312354.1 similar to acyltransferases e.g. [Neisseria meningitidis MC58] gi|7226953|gb|AAF42046.1| NP_312355.1 similar to acyl carrier proteins e.g. [Neisseria meningitidis MC58] gi|7226952|gb|AAF42045.1| NP_312356.1 carries the fatty acid chain in fatty acid biosynthesis NP_312357.1 similar to integral membrane protein [Neisseria meningitidis] gi|7380586|emb|CAB85174.1 NP_312358.1 similar to peptide synthase [Xylella fastidiosa] gi|9105980|gb|AAF83848.1|AE003941_2, p-coumaryl-CoA ligase [Rhodobacter sphaeroides] gi|2764724|emb|CAA05380.1 NP_312359.1 similar to (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratases e.g. [Salmonella typhimurium] gi|140182|sp|P21773|FABZ_SALTY NP_312360.1 similar to dolichyl-phosphate mannose synthase related protein Pyrococcus abyssi strain Orsay A75176 NP_312361.1 similar to hypothetical proteins e.g.[Deinococcus radiodurans] gi|7471367|pir||B75463 NP_312363.1 similar to membrane protein [Xylella fastidiosa] gi|9105671|gb|AAF83587.1|AE003918_9 NP_312365.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_312366.1 similar tobeta-hydroxydecanoyl-ACP dehydrase [Pseudomonas aeruginosa] gi|2384563|gb|AAC45619.1|, beta-hydroxydecanoyl-ACP dehydrase,; similar to hypothetical protein [Neisseria meningitidis MC58] gi|7226956|gb|AAF42049.1 NP_312367.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_312368.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP NP_312369.1 similar to YHHU_ECOLI gi|1789886 (conserved in Escherichia coli K-12) NP_312370.1 similar to NIKA_ECOLI gi|1789887 (conserved in Escherichia coli K-12) NP_312371.1 with NikACDE is involved in nickel transport into the cell NP_312372.1 with NikABDE is involved in nickel transport into the cell NP_312373.1 with NikABCE is involved in nickel transport into the cell NP_312374.1 with NikABCD is involved with nickel transport into the cell NP_312375.1 Inhibits transcription at high concentrations of nickel NP_312376.2 similar to transcription regulators e.g. [Escherichia coli] gi|129347|sp|P13669|FARR_ECOLI NP_312377.1 similar to PTS system enzyme IIA components e.g. [Escherichia coli K-12] gi|2507274|sp|P37187|PTKA_ECOLI, PTS system frucrose-specific enzyme IIBC component NP_312378.1 similar to PTS system, galactitol-specific IIB component [Escherichia coli K-12] gi|2507273|sp|P37188|PTKB_ECOLI NP_312379.1 similar to PTS system galactitol-specific enzyme IIC e.g. [Bacillus halodurans] gi|4512376|dbj|BAA75340.1 NP_312380.1 similar to sugar kinases e.g. xylulokinase (EC 2.7.1.17) [Lactobacillus pentosus] gi|139850|sp|P21939|XYLB_LACPE NP_312381.1 similar to phosphotransferase system HPr enzymes e.g. [Xylella fastidiosa] gi|9106413|gb|AAF84212.1|AE003971_11 NP_312382.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis NP_312383.1 similar to HicB-related protein [Xylella fastidiosa] gi|9106728|gb|AAF84477.1|AE003992_13, HicB [Haemophilus influenzae] gi|3603326|gb|AAC35810.1 NP_312384.1 similar to HicA [Haemophilus influenzae] gi|3603325|gb|AAC35809.1 NP_312385.2 similar to YHHJ_ECOLI gi|1789897 (conserved in Escherichia coli K-12) NP_312386.1 similar to YHIH_ECOLI gi|2367231 (conserved in Escherichia coli K-12) NP_312387.1 similar to YHII_ECOLI gi|1789900 (conserved in Escherichia coli K-12) NP_312388.1 similar to YHIJ_ECOLI gi|1789902 (conserved in Escherichia coli K-12) NP_312389.1 similar to YHIL_ECOLI gi|2367233, YHIK_ECOLI gi|1789903 NP_312390.1 similar to YHIM_ECOLI gi|1789905 (conserved in Escherichia coli K-12) NP_312391.1 similar to YHIN_ECOLI gi|2367234 (conserved in Escherichia coli K-12) NP_312392.1 similar to PITB_ECOLI gi|1789360 (conserved in Escherichia coli K-12) NP_312393.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress NP_312394.1 similar to USPA_ECOLI gi|1789909 (conserved in Escherichia coli K-12) NP_312395.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function NP_312396.1 predicted SAM-dependent methyltransferase NP_312397.1 similar to PRLC_ECOLI gi|1789913 (conserved in Escherichia coli K-12) NP_312398.1 similar to YHIR_ECOLI gi|1789914 (conserved in Escherichia coli K-12) NP_312399.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense NP_312400.1 regulates the expression of of the arsRBC involved in resistance to arsenic NP_312401.1 similar to ARSF_ECOLI gi|1789917 (conserved in Escherichia coli K-12) NP_312402.1 similar to ARSC_ECOLI gi|1789918 (conserved in Escherichia coli K-12) NP_312403.1 similar to YHIS_ECOLI gi|1789920 (conserved in Escherichia coli K-12) NP_312404.2 outer membrane protein; similar to SLP_ECOLI gi|1789922 (conserved in Escherichia coli K-12) NP_312405.1 similar to YHIF_ECOLI gi|1789923 (conserved in Escherichia coli K-12) NP_312407.1 similar to ChuA [Escherichia coli O157:H7 EDL933] gi|1763009|gb|AAC44857.1| NP_312409.1 similar to hypothetical protein ShuT [Shigella dysenteriae haem transport locus] gi|2967538|gb|AAC27815.1, hemin-binding proteins e.g. [Yersinia pestis] gi|6226635| NP_312410.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_312411.1 similar to hypothetical protein ShuX [Shigella dysenteriae haem transport locus] gi|2967537|gb|AAC27814.1|, hypothetical protein X [Yersinia pestis] gi|7467368|pir||T12066 NP_312412.1 similar to hypothetical protein ShuY [Shigella dysenteriae haem transport locus] gi|2967536|gb|AAC27813.1|, hypothetical protein Y [Yersinia pestis] gi|7467369|pir||T12067 NP_312413.1 similar to hypothetical protein ShuU [Shigella dysenteriae haem transport locus] gi|2967535|gb|AAC27812.1|, hemin permeases e.g. HmuU [Yersinia pestis] gi|6226636|sp|Q56992|HMUU_YER NP_312414.1 with HmuTU is involved in the transport of hemin NP_312415.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli NP_312416.1 similar to HDEB_ECOLI gi|1789925 (conserved in Escherichia coli K-12) NP_312417.1 inactive form NP_312418.1 similar to HDED_ECOLI gi|1789927 (conserved in Escherichia coli K-12) NP_312419.1 similar to YHIE_ECOLI gi|1789928 (conserved in Escherichia coli K-12) NP_312420.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds NP_312421.1 similar to YHIV_ECOLI gi|1789930 (conserved in Escherichia coli K-12) NP_312422.1 similar to YHIW_ECOLI gi|1789932 (conserved in Escherichia coli K-12) NP_312423.1 regulates genes in response to acid and/or during stationary phase NP_312424.1 similar to GADB_ECOLI gi|1787769 (conserved in Escherichia coli K-12) NP_312425.1 similar to YHJA_ECOLI gi|1789935 (conserved in Escherichia coli K-12) NP_312426.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose NP_312427.1 similar to YHJB_ECOLI gi|1789937 (conserved in Escherichia coli K-12) NP_312428.1 similar to YHJC_ECOLI gi|1789938 (conserved in Escherichia coli K-12) NP_312429.1 similar to YHJD_ECOLI gi|1789939 (conserved in Escherichia coli K-12) NP_312430.1 similar to YHJE_ECOLI gi|1789941 (conserved in Escherichia coli K-12) NP_312431.1 similar to YHJG_ECOLI gi|2367236 (conserved in Escherichia coli K-12) NP_312432.1 in Escherichia coli this protein is involved in flagellar function NP_312433.1 similar to KDGK_ECOLI gi|1789945 (conserved in Escherichia coli K-12) NP_312434.1 similar to YHJJ_ECOLI gi|1789946 (conserved in Escherichia coli K-12) NP_312435.1 involved in the transport of C4-dicarboxylates across the membrane NP_312436.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli NP_312437.1 similar to YHJL_ECOLI gi|2367239 (conserved in Escherichia coli K-12) NP_312438.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans NP_312439.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) NP_312440.2 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis NP_312441.1 similar to YHJQ_ECOLI gi|1789955 NP_312442.1 similar to YHJR_ECOLI gi|1789956 (conserved in Escherichia coli K-12) NP_312443.1 similar to YHJS_ECOLI gi|1789958 (conserved in Escherichia coli K-12) NP_312444.1 similar to YHJT_ECOLI gi|1789959 (conserved in Escherichia coli K-12) NP_312445.1 similar to YHJU_ECOLI gi|1789960 (conserved in Escherichia coli K-12) NP_312446.1 similar to YHJV_ECOLI gi|1789961 (conserved in Escherichia coli K-12) NP_312447.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides NP_312448.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF NP_312449.1 similar to DPPC_ECOLI gi|1789964 (conserved in Escherichia coli K-12) NP_312450.1 transports peptides consisting of two or three amino acids NP_312451.1 similar to DPPA_ECOLI gi|1789966 (conserved in Escherichia coli K-12) NP_312452.2 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide NP_312453.1 similar to fimbrial proteins e.g. long polar fimbrial minor protein precursor [Salmonella typhimurium] gi|1170819|sp|P43664|LPFE_SALTY NP_312454.1 similar to fimbrial proteins e.g. long polar fimbrial protein LpfD [Salmonella typhimurium] gi|1170818|sp|P43663|LPFD_SALTY NP_312457.2 probable fimbrial chaperone protein, similar to chaperones e.g. LpfB [Salmonella typhimurium] gi|1170816|sp|P43661|LPFB_SALTY NP_312458.1 similar to long polar fimbria protein A precursor, LpfA, of S. typhimurium, gi|1170815|sp|P43660|LPFA_SALTY NP_312459.1 similar to YHJX_ECOLI gi|1789969 (conserved in Escherichia coli K-12) NP_312460.2 similar to YHJY_ECOLI gi|1789970 (conserved in Escherichia coli K-12) NP_312461.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine NP_312462.1 similar to YIAC_ECOLI gi|1789972 (conserved in Escherichia coli K-12) NP_312463.1 similar to BISC_ECOLI gi|1789973 (conserved in Escherichia coli K-12) NP_312464.1 similar to YIAD_ECOLI gi|1789974 (conserved in Escherichia coli K-12) NP_312465.2 Involved in the metabolism of aromatic amino acids NP_312466.1 similar to YIAF_ECOLI gi|1789976 (conserved in Escherichia coli K-12) NP_312467.1 similar to YIAG_ECOLI gi|1789978 (conserved in Escherichia coli K-12) NP_312468.1 similar to CSPA_ECOLI gi|1789979 (conserved in Escherichia coli K-12) NP_312469.1 glycine--tRNA ligase subunit beta; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_312470.1 glycine--tRNA ligase subunit alpha; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_312471.1 similar to YIAH_ECOLI gi|1789984 (conserved in Escherichia coli K-12) NP_312472.2 similar to YIAA_ECOLI gi|1789985 (conserved in Escherichia coli K-12) NP_312473.1 similar to YIAB_ECOLI gi|1789986 (conserved in Escherichia coli K-12) NP_312474.1 similar to XYLB_ECOLI gi|1789987 (conserved in Escherichia coli K-12) NP_312475.1 catalyzes the interconversion of D-xylose to D-xylulose NP_312476.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity NP_312477.1 with XylFH is part of the high affinity xylose ABC transporter NP_312478.1 similar to XYLH_ECOLI gi|1789992 (conserved in Escherichia coli K-12) NP_312479.1 similar to XYLR_ECOLI gi|1789993 (conserved in Escherichia coli K-12) NP_312480.1 similar to BAX_ECOLI gi|1789994 (conserved in Escherichia coli K-12) NP_312481.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds NP_312482.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis NP_312483.1 similar to YIAI_ECOLI YIAI_ECOLI gi|2367245 (conserved in Escherichia coli K-12) NP_312484.1 similar to hypothetical transcriptional regulator YisR [Bacillus subtilis] gi|3123306|sp|P40331 NP_312485.1 similar to hypothetical proteins [Salmonella typhimurium] gi|7442781|pir||C65167, transport proteins ( symporters) e.g. YicJ [Escherichia coli (K-12)] gi|2851421|sp|P31435 NP_312486.1 similar to hypothetical protein [Thermotoga maritima] gi|7452109|pir||F72395 NP_312487.1 similar to YIAT_ECOLI gi|1790010 (conserved in Escherichia coli K-12) NP_312488.1 similar to YIAU_ECOLI gi|1790011 (conserved in Escherichia coli K-12) NP_312489.1 similar to YIAV_ECOLI gi|1790012 (conserved in Escherichia coli K-12) NP_312490.1 similar to YIAW_ECOLI gi|1790013 (conserved in Escherichia coli K-12) NP_312491.2 similar to ALDB_ECOLI gi|1790014 (conserved in Escherichia coli K-12) NP_312492.1 similar to hypothetical protein [Neisseria meningitidis MC58] gi|7227012|gb|AAF42100.1 NP_312493.1 similar to YIAY_ECOLI gi|1790015 (conserved in Escherichia coli K-12) NP_312494.1 similar to SELB_ECOLI gi|2367247 (conserved in Escherichia coli K-12) NP_312495.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis NP_312496.1 similar to YIBF_ECOLI gi|1790018 (conserved in Escherichia coli K-12) NP_312497.1 similar to Rhs core RHSA_ECOLI gi|1790020 (conserved in Escherichia coli K-12) NP_312498.1 similar to YIBG_ECOLI gi|1790023 (conserved in Escherichia coli K-12) NP_312500.1 similar to YIBH_ECOLI gi|1790024 NP_312501.1 similar to YIBI_ECOLI gi|1790025 (conserved in Escherichia coli K-12) NP_312502.1 similar to MTLA_ECOLI gi|1790027 (conserved in Escherichia coli K-12) NP_312503.1 similar to MTLD_ECOLI gi|1790028 (conserved in Escherichia coli K-12) NP_312504.1 Acts as a repressor of the mtlAD operon NP_312505.1 similar to YIBL_ECOLI gi|1790030 (conserved in Escherichia coli K-12) NP_312507.1 similar to surface proteins, e.g.[Xylella fastidiosa] gi|9106565|gb|AAF84338.1|AE003982_11 NP_312508.1 similar to LLDP_ECOLI gi|1790031 (conserved in Escherichia coli K-12) NP_312509.1 represses the lctPRD operon NP_312510.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration NP_312511.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates NP_312512.1 catalyzes the O-acetylation of serine NP_312513.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_312514.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA NP_312515.1 similar to GRXC_ECOLI gi|1790039 (conserved in Escherichia coli K-12) NP_312516.1 similar to YIBN_ECOLI gi|1790040 (conserved in Escherichia coli K-12) NP_312517.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate NP_312518.1 similar to YIBP_ECOLI gi|1790042 (conserved in Escherichia coli K-12) NP_312519.2 similar to YIBQ_ECOLI gi|1790043 (conserved in Escherichia coli K-12) NP_312520.1 similar to YIBD_ECOLI gi|1790044 (conserved in Escherichia coli K-12) NP_312521.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism NP_312522.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine NP_312523.1 similar to HTRL_ECOLI gi|1790048 (conserved in Escherichia coli K-12) NP_312524.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose NP_312525.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core NP_312526.1 similar to RFAC_ECOLI gi|1790051 (conserved in Escherichia coli K-12) NP_312527.1 WaaL; similar to WaaL [Escherichia coli strain F653] gi|3821825|gb|AAC69661.1| NP_312528.1 WaaD; similar to WaaD [Escherichia coli strain F653] gi|3821826|gb|AAC69662.1| NP_312529.1 WaaJ; similar to UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase WaaJ [Escherichia coli strain F653] gi|3821827|gb|AAC69663.1| NP_312530.1 similar to WaaY [Escherichia coli strain F653] gi|3821828|gb|AAC69664.1| NP_312531.1 similar to WaaI (strain F653 R3 core type) [Escherichia coli] gi|3821829|gb|AAC69665.1 NP_312532.2 similar to RFAP_ECOLI gi|1790060 (conserved in Escherichia coli K-12) NP_312533.1 similar to RFAG_ECOLI gi|1790061 (conserved in Escherichia coli K-12) NP_312534.2 (conserved in Escherichia coli K-12) NP_312535.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A NP_312536.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA NP_312537.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases NP_312538.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_312539.1 required for 70S ribosome assembly NP_312540.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase NP_312541.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine NP_312542.1 catalyzes the formation of dUMP from dUTP NP_312543.2 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly NP_312544.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate NP_312545.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs NP_312546.1 similar to YICC_ECOLI gi|1790075 (conserved in Escherichia coli K-12) NP_312547.2 similar to DIND_ECOLI gi|1790076 (conserved in Escherichia coli K-12) NP_312548.2 similar to YICG_ECOLI gi|1790078 (conserved in Escherichia coli K-12) NP_312549.2 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ NP_312550.1 Essential for recycling GMP and indirectly, cGMP NP_312551.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits NP_312552.1 similar to SPOT_ECOLI gi|1790082 (conserved in Escherichia coli K-12) NP_312553.1 specifically modifies tRNA at position G18 NP_312554.1 catalyzes branch migration in Holliday junction intermediates NP_312556.1 similar to GLTS_ECOLI gi|1790085 (conserved in Escherichia coli K-12) NP_312557.1 similar to YICE_ECOLI gi|1790087 (conserved in Escherichia coli K-12) NP_312558.1 similar to YICH_ECOLI gi|1790088 (conserved in Escherichia coli K-12) NP_312559.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides NP_312560.2 may be involved in the transport of galactosides-pentoses-hexuronides NP_312561.1 similar to CP4-like integrases [Escherichia coli EDL933] gi|3414871|gb|AAC31482.1|, integrases e.g. [Shigella flexneri] gi|5532446|gb|AAD44730.1|AF141323_1 NP_312562.1 similar to L0004 [Escherichia coli strain EDL933] gi|3414872|gb|AAC31483.1|, hypothetical protein [Escherichia coli plasmid pO157 insertion sequence IS911 gi|7465897|pir||T00224 NP_312563.1 similar to L0005 [Escherichia coli strain EDL933] gi|3414873|gb|AAC31484.1| NP_312564.1 similar to L0006 [Escherichia coli strain EDL933] gi|3414874|gb|AAC31485.1|, hypothetical protein [Vibrio cholerae] gi|7960027|gb|AAF71187.1|AF179596_7 NP_312565.1 similar to C-terminal parts of hypothetical proteins e.g. b2004 (YeeU) [Escherichia coli] gi|3025157|sp|P76364|YEEU_ECOLI NP_312566.1 similar to L0007 [Escherichia coli EDL933] gi|3414875|gb|AAC31486.1|, hypothetical proteins e.g. b2005 (yeeV) [Escherichia coli] gi|3025158|sp|P76365|YEEV_ECOLI NP_312567.1 similar to L0008 [Escherichia coli EDL933] gi|3414876|gb|AAC31487.1|, hypothetical protein [Escherichia coli D1114, O25:K10:H16] gi|4887094|gb|AAD32187.1|, b2006 (YeeW) NP_312568.1 similar to L0009 [Escherichia coli strain EDL933] gi|3414877|gb|AAC31488.1|, hypothetical protein [Escherichia coli D1114, O25:K10:H16] gi|4887094|gb|AAD32187.1 NP_312569.1 similar to L0010 [Escherichia coli strain EDL933] gi|3414878|gb|AAC31489.1|, PH01 [Escherichia coli D1114, O25:K10:H16] gi|4887092|gb|AAD32185.1|AF127177_3 NP_312572.1 similar to L0013 [Escherichia coli EDL933] gi|3414881|gb|AAC31492.1|, hypothetical proteins e.g. Hp3 [Escherichia coli CFT073] gi|3661484|gb|AAC61715.1| NP_312573.1 similar to L0014 [Escherichia coli] gi|3414882|gb|AAC31493.1|, hypothetical proteins e.g. orf50 [Escherichia coli plasmid pB171] gi|6009426|dbj|BAA84885.1| NP_312574.1 similar to L0015 [Escherichia coli EDL933] gi|3414883|gb|AAC31494.1|, hypothetical proteins e.g. [Escherichia coli plasmid pEAF] gi|4808945|gb|AAD30027.1|AF119170_2 NP_312575.1 similar to IS630 insertion element hypothetical protein gi|1143207|gb|AAA84873.1| NP_312577.1 similar to L0016 [Escherichia coli EDL933] gi|3414884|gb|AAC31495.1|, EspF [Escherichia coli E2348/69] gi|2865308|gb|AAC38400.1| NP_312578.1 similar to L0017 [Escherichia coli EDL933] gi|3414885|gb|AAC31496.1|, hypothetical protein [Escherichia coli] gi|2809428|gb|AAC28566.1| NP_312579.1 similar to EscF [Escherichia coli] gi|2865306|gb|AAC38398.1|, L0018 [Escherichia coli EDL933] gi|3414886|gb|AAC31497.1| NP_312580.1 similar to L0019 [Escherichia coli EDL933] gi|3414887|gb|AAC31498.1|, hypothetical proteins e.g. Orf27 [Escherichia coli E2348/69] gi|2865305|gb|AAC38397.1| NP_312581.1 secreted protein; similar to EspB proteins e.g. EspB(L0020) [Escherichia coli EDL933] gi|1657263|emb|CAA65654.1| NP_312582.1 secreted protein; similar to L0021 [Escherichia coli EDL933] gi|3414889|gb|AAC31500.1|, EspD proteins e.g. gi|3688279|emb|CAA76909.1| NP_312583.1 secreted protein; similar to EspA protein (L0022) [Escherichia coli] gi|3115184|emb|CAA73506.1|, EspA proteins e.g. gi|2388623|gb|AAB71083.1| NP_312584.1 similar to SepL (L0023) [Escherichia coli EDL933] gi|3115183|emb|CAA73505.1|, SepL proteins e.g. gi|2865301|gb|AAC38393.1|; type III secretion system protein NP_312585.1 similar to Pas (L0024) [Escherichia coli EDL933] gi|3115182|emb|CAA73504.1|, EscD proteins e.g. gi|3341420|emb|CAA74170.1|; type III secretion system protein NP_312586.1 similar to Gamma intimin (L0025) [Escherichia coli strain EDL933] gi|3414893|gb|AAC31504.1| NP_312587.1 chaperon of Tir; similar to CesT [Escherichia coli O157:H7 strain HA1] gi|975876|gb|AAB00110.1|, CesT proteins [Escherichia coli] gi|140611|sp|P21244|YEAE_ECOLI NP_312588.1 similar to translocated intimin receptor Tir (L0027) [Escherichia coli O157:H7 strain EDL933] gi|3414895|gb|AAC31506.1| NP_312589.1 similar to L0028 [Escherichia coli O157:H7 strain EDL933] gi|3414896|gb|AAC31507.1|, hypothetical protein [Escherichia coli] gi|3249026|gb|AAC69313.1| NP_312590.1 similar to L0029 [Escherichia coli O157:H7 strain EDL933] gi|3414897|gb|AAC31508.1|, rOrf10 [Escherichia coli] gi|2865295|gb|AAC38388.1| NP_312591.1 similar to L0030 [Escherichia coli O157:H7 strain EDL933] gi|3414898|gb|AAC31509.1|, Orf18 [Escherichia coli] gi|2865294|gb|AAC38387.1| NP_312592.1 similar to L0031 [Escherichia coli O157:H7 strain EDL933] gi|3414899|gb|AAC31510.1|, SepQ [Escherichia coli strain E2348/69] gi|2865293|gb|AAC38386.1|; type III secretion system protein NP_312593.1 similar to Orf16 [Escherichia coli strain E2348/69] gi|2865292|gb|AAC38385.1|, L0032 [Escherichia coli O157:H7 strain EDL933] gi|3414900|gb|AAC31511.1| NP_312594.1 similar to L0033 [Escherichia coli O157:H7 strain EDL933] gi|3414901|gb|AAC31512.1| NP_312595.1 similar to EscN (L00349 [Escherichia coli O157:H7 strain EDL933] gi|3414902|gb|AAC31513.1|; type III secretion system protein NP_312596.1 similar to EscV (L0035) [Escherichia coli O157:H7 strain EDL933] gi|3414903|gb|AAC31514.1| NP_312597.1 similar to Orf12 [Escherichia coli strain E2348/69] gi|2865288|gb|AAC38381.1|, L0036 [Escherichia coli O157:H7 strain EDL933] gi|3414904|gb|AAC31515.1| NP_312598.1 similar to SepZ proteins e.g. [Escherichia coli O157:H7 strain EDL933] gi|3414905|gb|AAC31516.1|; type III secretion system protein NP_312599.1 similar to L0038 [Escherichia coli O157:H7 strain EDL933] gi|3414906|gb|AAC31517.1|, rOrf8 [Escherichia coli E2348/69] gi|2865287|gb|AAC38380.1| NP_312600.1 similar to EscJ [Escherichia coli strain E2348/69] gi|2865286|gb|AAC38379.1|, L0039 (EscJ) [Escherichia coli O157:H7 strain EDL933] gi|3414907|gb|AAC31518.1|; type III secretion system protein NP_312601.1 similar to SepD (L0040) [Escherichia coli O157:H7 strain EDL933] gi|3414908|gb|AAC31519.1|, SepD proteins e.g. [Escherichia coli strain E2348/69] gi|886476|emb|CAA90273.1|; type III secretion system protein NP_312602.1 similar to EscC (L0041) [Escherichia coli O157:H7 strain EDL933] gi|3414909|gb|AAC31520.1|; type III secretion system protein NP_312603.1 similar to CesD (L0042) [Escherichia coli O157:H7 strain EDL933] gi|3414910|gb|AAC31521.1|; type III secretion system protein NP_312604.1 similar to L0043 [Escherichia coli O157:H7 strain EDL933] gi|3414911|gb|AAC31522.1|, Orf11 [Escherichia coli strain E2348/69] gi|2865282|gb|AAC38375.1| NP_312605.1 similar to L0044 [Escherichia coli O157:H7 strain EDL933] gi|3414912|gb|AAC31523.1|, Orf10 [Escherichia coli strain E2348/69] gi|2865281|gb|AAC38374.1| NP_312606.1 similar to L0045 [Escherichia coli O157:H7 strain EDL933] gi|3414913|gb|AAC31524.1|, rOrf3 [Escherichia coli strain E2348/69] gi|2865280|gb|AAC38373.1| NP_312607.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli NP_312608.1 similar to EscT (L0047) [Escherichia coli O157:H7 strain EDL933] gi|3414915|gb|AAC31526.1|; type III secretion system protein NP_312609.1 similar to EscS (L0048) [Escherichia coli O157:H7 strain EDL933] gi|3414916|gb|AAC31527.1|; type III secretion system protein NP_312610.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response NP_312611.1 similar to L0050 [Escherichia coli O157:H7 strain EDL933] gi|3414918|gb|AAC31529.1|, Orf5 [Escherichia coli strain E2348/69] gi|2865275|gb|AAC38368.1| NP_312612.1 similar to L0051 [Escherichia coli O157:H7 strain EDL933] gi|3414919|gb|AAC31530.1|, Orf4 [Escherichia coli strain E2348/69] gi|2865274|gb|AAC38367.1| NP_312613.1 similar to Orf3 [Escherichia coli E2348/69] gi|2865273|gb|AAC38366.1|, L0052 [Escherichia coli O157:H7 strain EDL933] gi|3414920|gb|AAC31531.1| NP_312614.1 similar to Orf2 [Escherichia coli strain E2348/69] gi|2865272|gb|AAC38365.1|, L0053 [Escherichia coli O157:H7 strain EDL933] gi|3414921|gb|AAC31532.1| NP_312615.1 similar to L0054 [Escherichia coli O157:H7 strain EDL933] gi|3414922|gb|AAC31533.1|, Ler [Escherichia coli strain E2348/69] gi|2865271|gb|AAC38364.1| NP_312617.1 similar to L0055 [Escherichia coli O157:H7 strain EDL933] gi|3414923|gb|AAC31534.1|, rOrf2, EspG [Escherichia coli strain E2348/69] gi|2865270|gb|AAC38363.1| NP_312618.1 similar to L0056 [Escherichia coli O157:H7 strain EDL933] gi|3414924|gb|AAC31535.1|, rOrf1 [Escherichia coli strain E2348/69] gi|2865269|gb|AAC38362.1| NP_312621.1 similar to YICL_ECOLI gi|1790092 (conserved in Escherichia coli K-12) NP_312622.1 similar to NLPA_ECOLI gi|1790093 (conserved in Escherichia coli K-12) NP_312623.2 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS NP_312624.1 similar to hypothetical proteins e.g. NMA0565 [Neisseria meningitidis] gi|7379302|emb|CAB83857.1 NP_312625.1 similar to DNA-binding protein [Neisseria meningitidis] gi|7379301|emb|CAB83856.1 NP_312626.1 similar to YICN_ECOLI gi|1790096 (conserved in Escherichia coli K-12) NP_312627.1 similar to YICO_ECOLI gi|1790097 NP_312628.1 similar to YICO_ECOLI gi|1790097 NP_312629.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type NP_312630.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate NP_312631.1 membrane protein regulates uhpT expression NP_312632.2 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph NP_312633.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter NP_312638.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit NP_312639.1 catalyzes the formation of 2-acetolactate from pyruvate NP_312640.1 similar to IVBL_ECOLI gi|1790106 (conserved in Escherichia coli K-12) NP_312641.1 multidrug efflux protein involved in adaptation to low energy shock NP_312642.1 similar to YIDF_ECOLI gi|1790108 (conserved in Escherichia coli K-12) NP_312643.1 similar to YIDG_ECOLI gi|1790109 (conserved in Escherichia coli K-12) NP_312644.1 similar to YIDH_ECOLI gi|1790110 (conserved in Escherichia coli K-12) NP_312645.1 similar to YIDI_ECOLI gi|1790111 (conserved in Escherichia coli K-12) NP_312646.1 similar to YIDJ_ECOLI gi|1790112 (conserved in Escherichia coli K-12) NP_312647.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function NP_312648.1 similar to YIDL_ECOLI gi|1790114 (conserved in Escherichia coli K-12) NP_312649.1 similar to GLVG_ECOLI gi|1790115 (conserved in Escherichia coli K-12) NP_312650.2 similar to GLVC_ECOLI gi|1790117 (conserved in Escherichia coli K-12) NP_312651.1 similar to YIDP_ECOLI gi|1790118 (conserved in Escherichia coli K-12) NP_312652.2 similar to YIDE_ECOLI gi|1790119 (conserved in Escherichia coli K-12) NP_312653.2 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent NP_312654.1 heat shock protein; with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress NP_312655.2 similar to YIDQ_ECOLI gi|1790123 (conserved in Escherichia coli K-12) NP_312656.1 similar to YIDR_ECOLI gi|1790124 (conserved in Escherichia coli K-12) NP_312657.2 FAD/NAD(P)-binding domain NP_312658.1 similar YIDX_ECOLI gi|1790130 NP_312659.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins NP_312660.2 similar to YIDB_ECOLI gi|1790133 (conserved in Escherichia coli K-12) NP_312661.1 negatively supercoils closed circular double-stranded DNA NP_312662.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_312663.1 binds the polymerase to DNA and acts as a sliding clamp NP_312664.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_312665.1 in Escherichia coli transcription of this gene is enhanced by polyamines NP_312666.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_312667.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_312668.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_312670.1 similar to ankyrin-like regulatory protein [Escherichia coli] gi|418526|sp|P23325|APR_ECOLI, ShET2 enterotoxin [Shigella flexneri] gi|1109754|emb|CAA90938.1| NP_312671.1 similar to TNAL_ECOLI gi|1790143 (conserved in Escherichia coli K-12) NP_312672.2 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan NP_312673.1 tryptophan transporter of low affinity NP_312674.1 Confers resistance to chloramphenicol NP_312675.1 Involved in anaerobic NO protection NP_312676.1 similar to YIEE_ECOLI gi|1790148 (conserved in Escherichia coli K-12) NP_312677.1 similar to YIEF_ECOLI gi|1790149 (conserved in Escherichia coli K-12) NP_312678.1 similar to YIEG_ECOLI gi|1790150 (conserved in Escherichia coli K-12) NP_312679.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily NP_312680.1 similar to hypothetical protein [Plasmodium falciparum] gi|8052285|emb|CAB39037.2|, restriction-modification enzyme R subunits [Mycoplasma pulmonis] e.g. gi|1363459|pir||S49394 NP_312684.1 similar to hypothetical protein [Plasmodium falciparum] gi|8052290|emb|CAB39073.2| NP_312687.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon NP_312688.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation NP_312689.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions NP_312690.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions NP_312691.1 similar to PSTS_ECOLI gi|2367271 (conserved in Escherichia coli K-12) NP_312692.1 similar to fimbrial proteins e.g. [Salmonella typhimurium] gi|1170818|sp|P43663|LPFD_SALTY, [Escherichia coli] gi|3915422|sp|P75858|YCBT_ECOLI NP_312693.1 similar to fimbrial proteins e.g. [Escherichia coli] gi|3915422|sp|P75858|YCBT_ECOLI, [Salmonella typhimurium] gi|1170818|sp|P43663|LPFD_SALTY NP_312694.1 similar to outer membrane usher protein precursors e.g. [Salmonella typhimurium] gi|1170817|sp|P43662|LPFC_SALTY, [Escherichia coli] gi|2829634|sp|P75857|YCBS_ECOLI NP_312695.1 similar to fimbrial chaperone e.g. gi|1169720|sp|P46008|FOCC_ECOLI NP_312696.1 similar to fimbrial chaperones e.g. [Salmonella typhimurium] gi|1170816|sp|P43661|LPFB_SALTY NP_312697.1 similar to type 1 fimbrial proteins e.g. [Salmonella enteritidis] gi|913907|gb|AAB33536.1| NP_312698.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_312699.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis NP_312700.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane NP_312701.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The subunit beta is a regulatory subunit NP_312702.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit NP_312703.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit alpha is a catalytic subunit NP_312704.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex NP_312705.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. NP_312706.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 NP_312707.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 NP_312708.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation NP_312709.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA NP_312710.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_312711.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group NP_312712.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase NP_312713.1 catalyzes the formation of asparagine from aspartate and ammonia NP_312714.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA NP_312715.2 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase NP_312716.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH NP_312717.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source NP_312718.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain NP_312719.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B NP_312720.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system NP_312721.1 catalyzes the formation of D-ribose 5-phosphate from ribose NP_312722.1 DNA-binding transcriptional repressor of ribose metabolism NP_312723.1 similar to YIEO_ECOLI gi|1790195 (conserved in Escherichia coli K-12) NP_312724.2 similar to YIEP_ECOLI gi|1790196 (conserved in Escherichia coli K-12) NP_312725.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon NP_312726.1 similar to YIFE_ECOLI gi|2367277 (conserved in Escherichia coli K-12) NP_312727.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function NP_312728.1 similar to ILVL_ECOLI gi|1790202 (conserved in Escherichia coli K-12) NP_312729.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit NP_312730.1 similar to ILVM_ECOLI gi|1790204 (conserved in Escherichia coli K-12) NP_312731.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids NP_312732.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis NP_312733.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway NP_312734.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate NP_312735.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis NP_312736.1 similar to PPIC_ECOLI gi|1790211 (conserved in Escherichia coli K-12) NP_312737.1 similar to YIFN_ECOLI gi|2367280, b3776_ECOLI gi|2367279 NP_312738.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication NP_312739.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation NP_312740.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation NP_312741.1 similar to TRXA_ECOLI gi|1790215 (conserved in Escherichia coli K-12) NP_312742.1 similar to RHOL_ECOLI gi|1790216 (conserved in Escherichia coli K-12) NP_312743.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_312744.1 similar to RFE_ECOLI gi|1790218 (conserved in Escherichia coli K-12) NP_312745.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein NP_312746.1 similar to WECB_ECOLI gi|2367283 (conserved in Escherichia coli K-12) NP_312747.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid NP_312748.1 similar to RFFG_ECOLI gi|1790223 (conserved in Escherichia coli K-12) NP_312749.1 similar to RFFH_ECOLI gi|1790224 (conserved in Escherichia coli K-12) NP_312750.1 similar to WECD_ECOLI gi|1790225 (conserved in Escherichia coli K-12) NP_312751.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis NP_312752.1 similar to WZXE_ECOLI gi|1790227 (conserved in Escherichia coli K-12) NP_312753.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis NP_312754.1 enterobacterial common antigen polymerase NP_312755.1 similar to WECG_ECOLI gi|2367289 (conserved in Escherichia coli K-12) NP_312756.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function NP_312757.1 similar to ASLB_ECOLI gi|2367292 (conserved in Escherichia coli K-12) NP_312758.1 similar to ASLA_ECOLI gi|1790233 (conserved in Escherichia coli K-12) NP_312759.1 similar to HEMY_ECOLI gi|1790234 (conserved in Escherichia coli K-12) NP_312760.1 similar to HEMX_ECOLI gi|1790235 NP_312761.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis NP_312762.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_312763.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP NP_312764.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly NP_312765.1 similar to B3808_ECOLI gi|1790240 (conserved in Escherichia coli K-12) NP_312766.2 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_312767.1 similar to YIGA_ECOLI gi|1790243 (conserved in Escherichia coli K-12) NP_312768.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_312769.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function NP_312770.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. NP_312771.1 similar to conserved hypothetical proteins e.g. HP0709 [Helicobacter pylori 26695] gi|7463979|pir||E64608 NP_312772.1 similar to YIGE_ECOLI gi|1790248, B3814_ECOLI gi|1790247 NP_312773.1 responsible for the influx of magnesium ions NP_312774.1 similar to hypothetical protein [Xylella fastidiosa] gi|9104946|gb|AAF82968.1|AE003869_5 NP_312776.1 similar to RARD_ECOLI gi|1790252 (conserved in Escherichia coli K-12) NP_312777.2 similar to YIGI_ECOLI gi|2367298 (conserved in Escherichia coli K-12) NP_312778.1 catalyzes the hydrolysis of phosphatidylcholine NP_312779.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway NP_312780.1 similar to RHTC_ECOLI gi|2851443|sp|P27846 (conserved in Escherichia coli K-12) NP_312781.1 similar to RHTB_ECOLI gi|6093972|sp|P27847 (conserved in Escherichia coli K-12) NP_312782.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates NP_312783.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium NP_312784.1 similar to YIGM_ECOLI gi|1790261 (conserved in Escherichia coli K-12) NP_312785.1 similar to METR_ECOLI gi|1790262 (conserved in Escherichia coli K-12) NP_312786.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine NP_312787.1 similar to YSGA_ECOLI gi|2367305 NP_312788.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway NP_312789.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner NP_312790.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_312791.1 similar to YIGP_ECOLI gi|2367308 (conserved in Escherichia coli K-12) NP_312792.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions NP_312793.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes NP_312794.1 mediates the export of protein precursors bearing twin-arginine signal peptides NP_312795.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane NP_312796.1 magnesium dependent; not involved in the Sec-independent protein export system NP_312797.1 transcriptional activator; similar to RFAH_ECOLI gi|1790276 (conserved in Escherichia coli K-12) NP_312798.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol NP_312799.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin NP_312800.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids NP_312801.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids NP_312802.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters NP_312803.2 similar to YIGZ_ECOLI gi|1790283 (conserved in Escherichia coli K-12) NP_312804.1 similar to TRKH_ECOLI gi|2367317, TRKH_ECOLI SW: P21166 (conserved in Escherichia coli K-12) NP_312805.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX NP_312806.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway NP_312807.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis NP_312808.1 similar to YIHD_ECOLI gi|1790289 (conserved in Escherichia coli K-12) NP_312809.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages NP_312810.1 similar to DSBA_ECOLI gi|1790291 (conserved in Escherichia coli K-12) NP_312811.2 similar to YIHF_ECOLI gi|2367319 (conserved in Escherichia coli K-12) NP_312812.1 similar to YIHG_ECOLI gi|1790293 (conserved in Escherichia coli K-12) NP_312813.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_312814.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential NP_312815.1 similar to YIHI_ECOLI gi|1790297 (conserved in Escherichia coli K-12) NP_312816.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_312817.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 NP_312818.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation NP_312819.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme NP_312820.1 similar to YIHK_ECOLI gi|1790302 (conserved in Escherichia coli K-12) NP_312821.1 similar to YIHL_ECOLI gi|1790304 (conserved in Escherichia coli K-12) NP_312822.1 similar to YIHM_ECOLI gi|1790305 (conserved in Escherichia coli K-12) NP_312823.1 similar to YIHN_ECOLI gi|1790306 (conserved in Escherichia coli K-12) NP_312824.2 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown NP_312825.1 similar to YIHO_ECOLI gi|2367321 (conserved in Escherichia coli K-12) NP_312826.1 similar to YIHP_ECOLI gi|2367322 (conserved in Escherichia coli K-12) NP_312827.1 similar to YIHQ_ECOLI gi|2367323 (conserved in Escherichia coli K-12) NP_312828.1 similar to membrane protein [Staphylococcus aureus] gi|3676428|gb|AAC61946.1 NP_312829.1 similar to YIHR_ECOLI gi|1790311 (conserved in Escherichia coli K-12) NP_312830.1 similar to YIHS_ECOLI gi|1790313 (conserved in Escherichia coli K-12) NP_312831.1 similar to YIHT_ECOLI gi|1790314 (conserved in Escherichia coli K-12) NP_312832.1 similar to YIHU_ECOLI gi|1790315 (conserved in Escherichia coli K-12) NP_312833.1 similar to YIHV_ECOLI gi|1790316 (conserved in Escherichia coli K-12) NP_312834.1 similar to YIHW_ECOLI gi|1790317 (conserved in Escherichia coli K-12) NP_312835.2 similar to YIHX_ECOLI gi|1790318 (conserved in Escherichia coli K-12) NP_312836.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease NP_312837.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine NP_312838.1 similar to YIID_ECOLI gi|1790321 (conserved in Escherichia coli K-12) NP_312842.1 similar to YIIE_ECOLI gi|1790322 (conserved in Escherichia coli K-12) NP_312843.1 similar to YIIF_ECOLI gi|1790323 (conserved in Escherichia coli K-12) NP_312844.1 required for the formation of active formate dehydrogenase NP_312845.1 cytochrome b556(FDO) component; heme containing NP_312846.1 similar to FDOH_ECOLI gi|1790326 (conserved in Escherichia coli K-12) NP_312847.1 similar to FDOG_ECOLI gi|3868719 (conserved in Escherichia coli K-12) NP_312848.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth NP_312849.1 similar to YIIG_ECOLI gi|1790330 (conserved in Escherichia coli K-12) NP_312850.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system NP_312851.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars NP_312852.1 similar to PTVB_ECOLI gi|1790333 (conserved in Escherichia coli K-12) NP_312853.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system NP_312854.1 similar to RafY [Escherichia coli plasmid pRSD2] gi|1773072|gb|AAB71432.1 NP_312855.1 similar to YIIL_ECOLI gi|1790335 (conserved in Escherichia coli K-12) NP_312856.1 similar to RHAD_ECOLI gi|1790336 (conserved in Escherichia coli K-12) NP_312857.1 catalyzes the formation of L-rhamnulose from L-rhamnose NP_312858.1 catalyzes the ATP-dependent phosphorylation of rhamnulose NP_312859.1 activates the expression of the rhaBAD operon and rhaT gene NP_312860.1 activates the expression of rhaRS in response to L-rhamnose NP_312861.2 SodA; manganese binding; only present under aerobic conditions; destroys free radicals NP_312862.2 transports degraded pectin products into the bacterial cell NP_312863.2 similar to YIIM_ECOLI gi|1790345 (conserved in Escherichia coli K-12) NP_312864.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors NP_312865.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system NP_312866.2 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates NP_312867.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers NP_312868.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis NP_312869.1 similar to SBP_ECOLI gi|1790351 (conserved in Escherichia coli K-12) NP_312870.1 similar to CDH_ECOLI gi|1790352 (conserved in Escherichia coli K-12) NP_312871.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_312872.1 similar to YIIQ_ECOLI gi|1790354 (conserved in Escherichia coli K-12) NP_312873.1 similar to YIIR_ECOLI gi|1790355 (conserved in Escherichia coli K-12) NP_312874.1 similar to YIIS_ECOLI gi|1790357 (conserved in Escherichia coli K-12) NP_312875.1 with UspC and Usp E is involved in resistance to UV radiation NP_312876.1 similar to FPR_ECOLI gi|1790359 (conserved in Escherichia coli K-12) NP_312877.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese NP_312878.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP NP_312879.1 similar to GLPF_ECOLI gi|1790362 (conserved in Escherichia coli K-12) NP_312880.2 similar to YIIU_ECOLI gi|1790363 (conserved in Escherichia coli K-12) NP_312883.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity NP_312884.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate NP_312885.1 heat shock protein involved in degradation of misfolded proteins NP_312886.1 heat shock protein involved in degradation of misfolded proteins NP_312887.1 similar to FTSN_ECOLI gi|1790368 (conserved in Escherichia coli K-12) NP_312888.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins NP_312889.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_312890.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_312891.1 RhsH core protein with extension; similar to Rhs proteins e.g. RhsF [Escherichia coli] gi|2920637|gb|AAC32473.1| NP_312893.1 member of the NlpC/P60 superfamily of peptidases NP_312894.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis NP_312895.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine NP_312896.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways NP_312897.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor NP_312898.1 similar to KATG_ECOLI gi|1790378 (conserved in Escherichia coli K-12) NP_312899.2 similar to YIJE_ECOLI gi|1790379 (conserved in Escherichia coli K-12) NP_312900.1 similar to YIJF_ECOLI gi|1790380 (conserved in Escherichia coli K-12) NP_312901.2 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone NP_312902.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies NP_312903.2 similar to PTSA_ECOLI gi|1790383 (conserved in Escherichia coli K-12) NP_312904.1 similar to YIJI_ECOLI gi|1790384 NP_312906.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS NP_312907.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein NP_312908.2 similar to PFLC_ECOLI gi|1790389 (conserved in Escherichia coli K-12) NP_312909.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog NP_312910.1 similar to YIJO_ECOLI gi|1790391 (conserved in Escherichia coli K-12) NP_312911.1 similar to YIJP_ECOLI gi|4741821|gb|AAD28716.1|AF112861_1 (conserved in Escherichia coli K-12) NP_312912.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate NP_312913.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis NP_312914.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate NP_312915.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate NP_312916.1 catalyzes the formation of arginine from (N-L-arginino)succinate NP_312917.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA NP_312918.2 catalyzes the conversion of NADPH to NADH NP_312919.1 similar to amino acid amidohydrolases e.g. benzoylglycine amidohydrolase (Hippuricase) [Campylobacter jejuni] gi|1170277|spP45493|HIPO_CAMJE NP_312920.1 similar to membrane transport proteins e.g. citrate-proton symporter [Klebsiella pneumoniae] gi|116482|sp|P16482|CIT1_KLEPN NP_312921.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis NP_312922.1 similar to YIJD_ECOLI gi|1790402 (conserved in Escherichia coli K-12) NP_312923.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs NP_312924.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space NP_312925.2 converts L-glutamate to D-glutamate, a component of peptidoglycan NP_312926.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_312927.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_312928.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis NP_312929.1 similar to B3975_ECOLI gi|1790411 NP_312930.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_312931.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_312932.1 Modulates Rho-dependent transcription termination NP_312933.1 binds directly to 23S ribosomal RNA NP_312934.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_312935.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_312936.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_312937.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_312938.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_312939.1 heat shock protein; similar to HTRC_ECOLI gi|1790422 NP_312940.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center NP_312941.2 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate NP_944578.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate NP_312942.2 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate NP_312943.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate NP_312944.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine NP_312945.1 binds specifically to the major sigma factor sigma 70; active in stationary phase NP_312946.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates NP_312947.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_312948.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures NP_312949.1 similar to YJAG_ECOLI gi|1790432 (conserved in Escherichia coli K-12) NP_312950.1 histone-like DNA-binding protein NP_312951.1 similar to YJAH_ECOLI gi|1790434 (conserved in Escherichia coli K-12) NP_312952.2 similar to YJAI_ECOLI gi|1790435 (conserved in Escherichia coli K-12) NP_312953.1 sensor kinase; similar to HYDH_ECOLI gi|1790436 (conserved in Escherichia coli K-12) NP_312954.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein NP_312955.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis NP_312956.1 involved in de novo purine biosynthesis NP_312957.1 similar to YJAB_ECOLI gi|1790442 (conserved in Escherichia coli K-12) NP_312958.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis NP_312959.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle NP_312960.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates NP_312961.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol NP_312962.1 similar to ARP_ECOLI gi|1790447 (conserved in Escherichia coli K-12) NP_312963.2 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase NP_312964.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity NP_312965.1 similar to YJBB_ECOLI gi|1790451 (conserved in Escherichia coli K-12) NP_312966.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family NP_312967.1 similar to hypothetical protein b3122 [Escherichia coli (strain K-12)] gi|7466507|pir||G65101 NP_312968.1 similar to L-sorbose 1-phosphate dehydrogenases, e.g. [Klebsiella pneumoniae] gi|586014|sp|P37084|SORE_KLEPN NP_312970.1 repressor; similar to hypothetical protein HI1476 [Haemophilus influenzae] gi|1175815|sp|P44207|YE76_HAEIN, probable repressor protein [Bacteriophage D1] NP_312971.1 similar to Ner-like DNA-binding proteins e.g. gi|6900348|emb|CAB71960.1| NP_312972.1 similar to transposases e.g. [Neisseria meningitidis] gi|7379960|emb|CAB84536.1| NP_312973.1 similar to DNA transposition protein B [Bacteriophage Mu] gi|139318|sp|P03763|VPB_BPMU NP_312974.1 similar to phosphoserine phosphatase [Neisseria meningitidis MC58] gi|7226221|gb|AAF41385.1| NP_312979.1 similar to host-nuclease inhibitor proteins (Gam) e.g. [Bacteriophage Mu] gi|138127|sp|P06023|VGAM_BPMU NP_312981.1 similar to Gp11 [Bacteriophage Mu] gi|6010385|gb|AAF01088.1|AF083977_7 NP_312982.1 similar to gp12 [Bacteriophage Mu] gi|215568|gb|AAA32400.1| NP_312983.1 similar to gp9 [Bacteriophage Mu] gi|6010430|gb|AAF01133.1|AF083977_54 NP_312985.1 similar to zinc finger proteins e.g. [Rattus norvegicus] gi|141712|sp|P18745|ZO22_XENLA NP_312987.1 similar to hypothetical proteins e.g. gp16 [Bacteriophage Mu] gi|6010390|gb|AAF01093.1|AF083977_12 NP_312988.1 probable positive regulator of late transcription; similar to transcription regulators e.g. positive regulator of late transcription (protein C) [Bacteriophage Mu] gi|139320|sp|P06022|VPC_BPMU NP_312989.1 endolysin (host cell lysis); similar to endolysins e.g. Lys [Bacteriophage Mu] |126600|sp|P27359|LYCV_BPP21 NP_312991.1 similar to P16 [Bacteriophage APSE-1] gi|6118011|gb|AAF03959.1|AF157835_16 NP_312992.1 similar to traR family, e.g. Orf82 [Bacteriophage P2] gi|732223|sp|Q06424|YO82_BPP2 NP_312993.1 similar to gp25 [Bacteriophage Mu] gi|6010400|gb|AAF01103.1|AF083977_22 NP_312994.1 similar to hypothetical proteins e.g. gp26 [Bacteriophage Mu] gi|6010401|gb|AAF01104.1|AF083977_23 NP_312995.1 similar to hypothetical proteins e.g. gp27 [Bacteriophage Mu] gi|6010402|gb|AAF01105.1|AF083977_24 NP_312996.1 similar to hypothetical proteins e.g. gp28 (possible portal protein H) [Bacteriophage Mu] gi|6010403|gb|AAF01106.1|AF083977_25 NP_312997.1 similar to hypothetical proteins e.g. gp29 [Bacteriophage Mu] gi|6010404|gb|AAF01107.1|AF083977_26 NP_312998.1 similar to hypothetical proteins e.g. gp30 [Bacteriophage Mu] gi|6010405|gb|AAF01108.1|AF083977_27 NP_312999.1 similar to G protein [Bacteriophage Mu] gi|267389|sp|Q01261|VPG_BPMU NP_313000.1 similar to gpI [Bacteriophage Mu] gi|7226336|gb|AAF41489.1|; contains potential internal start site for homologue of p20 (Z)- the postulated scaffold protein NP_313001.1 similar to protein T [Bacteriophage Mu] gi|6010409|gb|AAF01112.1|AF083977_31, hypothetical proteins e.g. [Neisseria meningitidis] gi|6900377|emb|CAB71989.1| NP_313002.1 similar to gp35 [Bacteriophage Mu] gi|6010410|gb|AAF01113.1|AF083977_32 NP_313003.1 similar to hypothetical proteins e.g. gp36 [Bacteriophage Mu] gi|6010411|gb|AAF01114.1|AF083977_33 NP_313004.1 similar to hypothetical proteins e.g. gp37 [Bacteriophage Mu] gi|1175870|sp|P44231|YF09_HAEIN NP_313005.1 similar to hypothetical proteins e.g. gp38 [Bacteriophage Mu] gi|6010413|gb|AAF01116.1|AF083977_35 NP_313006.1 similar to sheath protein GpL [Bacteriophage Mu] gi|1834291|dbj|BAA19195.1|, hypothetical proteins e.g. [Haemophilus influenzae Rd] gi|1175872|sp|P44233|YF11_HAEIN NP_313007.1 similar to hypothetical proteins e.g. GpM [Bacteriophage Mu] gi|1834292|dbj|BAA19196.1| NP_313008.1 similar to hypothetical proteins e.g. ORF3 [Bacteriophage Mu] gi|1834293|dbj|BAA19197.1| NP_313009.1 similar to hypothetical proteins e.g. Gp42 (probable tape measure protein) [Bacteriophage Mu] gi|6010417|gb|AAF01120.1|AF083977_39 NP_313010.1 similar to DNA circulation proteins e.g. protein N? [Bacteriophage Mu] gi|6010418|gb|AAF01121.1|AF083977_40 NP_313011.1 similar to tail proteins e.g. P protein [Bacteriophage Mu] gi|139353|sp|P08558|VPP_BPMU NP_313012.1 similar to hypothetical proteins e.g. gp45 [Bacteriophage Mu] gi|6010420|gb|AAF01123.1|AF083977_42; may be involved in base plate assemblyy NP_313013.1 similar to hypothetical proteins e.g. Gp46 [Bacteriophage Mu] gi|6010421|gb|AAF01124.1|AF083977_43 NP_313014.1 similar to hypothetical proteins e.g. Gp47 [Bacteriophage Mu] gi|6010422|gb|AAF01125.1|AF083977_44 NP_313015.1 similar to hypothetical proteins e.g. Gp48 [Bacteriophage Mu] gi|6010423|gb|AAF01126.1|AF083977_45 NP_313016.1 similar to S protein [Bacteriophage Mu] gi|6010424|gb|AAF01127.1|AF083977_46, hypothetical proteins e.g. Bcv [Shigella boydii] gi|96900|pir||A42463 NP_313017.1 similar to [Bacteriophage 186] gi|3522882|gb|AAC34165.1|, tail fiber assembly proteins e.g. U protein [Bacteriophage Mu] gi|6010425|gb|AAF01128.1 NP_313018.1 similar to carboxyl terminal part of tail fiber proteins e.g. S [Bacteriophage Mu] gi|6010424|gb|AAF01127.1|AF083977_46 NP_313019.1 similar to site-specific recombinases e.g. DNA-invertase Gin [Bacteriophage Mu] gi|6010426|gb|AAF01129.1|AF083977_50 NP_313020.1 similar to hypothetical proteins e.g. L0105 [Bacteriophage 933W] gi|4585419|gb|AAD25447.1|AF125520_42 NP_313021.1 similar to orf25 [Bacteriophage 933W] gi|4499806|emb|CAB39305.1| NP_313022.1 similar to hypothetical proteins e.g. L0106 [Bacteriophage 933W] gi|4585420|gb|AAD25448.1|AF125520_43 NP_313024.1 similar to translational regulators e.g. Com protein (translational regulator of Mom) [Bacteriophage Mu] gi|7388376|sp|Q53979|VCOM_SHIDY NP_313025.1 similar to DNA modification proteins e.g. Mom protein [Bacteriophage Mu] gi|138782|sp|P06018|VMOM_BPMU NP_313027.1 similar to sorbose-permease IIC components e.g. [Klebsiella pneumoniae] gi|548633|sp|P37082|PTRC_KLEPN NP_313028.1 similar to sorbose-permease IIB components e.g. [Klebsiella pneumoniae] gi|1142714|gb|AAB04152.1| NP_313029.1 similar to sorbose-permease IIA components, e.g. [Klebsiella pneumoniae] gi|548631|sp|P37080|PTRA_KLEPN NP_313030.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate NP_313031.2 similar to sor-operon regulators (SorC family) [Klebsiella pneumoniae] gi|548950|sp|P37078|SORC_KLEPN NP_313032.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA NP_313033.1 similar to YJBD_ECOLI gi|1790454 (conserved in Escherichia coli K-12) NP_313034.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive NP_313035.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_313036.1 similar to YJBE_ECOLI gi|1790458 (conserved in Escherichia coli K-12) NP_313037.2 similar to YJBF_ECOLI gi|1790459 (conserved in Escherichia coli K-12) NP_313038.1 similar to YJBG_ECOLI gi|1790460 (conserved in Escherichia coli K-12) NP_313039.1 similar to YJBH_ECOLI gi|1790461 (conserved in Escherichia coli K-12) NP_313040.1 similar to YJBA_ECOLI gi|1790462 (conserved in Escherichia coli K-12) NP_313041.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter NP_313042.1 with MalKFE is involved in the transport of maltose into the cell NP_313043.1 with MalKGE is involved in maltose transport into the cell NP_313044.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis NP_313045.1 with malEFG is involved in import of maltose/maltodextrin NP_313046.1 porin involved in the transport of maltose and maltodextrins NP_313047.1 similar to MALM_ECOLI gi|1790470 (conserved in Escherichia coli K-12) NP_313048.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations NP_313049.2 catalyzes the formation of 4-hydroxybenzoate from chorismate NP_313050.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway NP_313051.2 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA NP_313052.1 similar to DGKA_ECOLI gi|1790475 (conserved in Escherichia coli K-12) NP_313053.1 Represses a number of genes involved in the response to DNA damage NP_313054.2 similar to DINF_ECOLI gi|1790477 (conserved in Escherichia coli K-12) NP_313055.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential NP_313056.2 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB NP_313057.1 similar to YJBL_ECOLI gi|1790481, YJBM_ECOLI gi|1790482 NP_313058.1 similar to YJBN_ECOLI gi|1790483 (conserved in Escherichia coli K-12) NP_313059.2 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia NP_313060.1 similar to QOR_ECOLI gi|1790485 (conserved in Escherichia coli K-12) NP_313061.1 unwinds double stranded DNA NP_313062.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer NP_313063.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate NP_313064.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity NP_313065.1 similar to YJBQ_ECOLI gi|1790491 (conserved in Escherichia coli K-12) NP_313066.1 similar to YJBR_ECOLI gi|2367342 (conserved in Escherichia coli K-12) NP_313067.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_313068.1 binds to single stranded DNA and PriA helcase facilitate replication restart NP_313069.2 similar to YJCB_ECOLI gi|1790495 (conserved in Escherichia coli K-12) NP_313070.1 similar to YJCC_ECOLI gi|1790496 (conserved in Escherichia coli K-12) NP_313071.1 regulates genes involved in response to oxidative stress NP_313072.1 similar to SOXR_ECOLI gi|1790498 (conserved in Escherichia coli K-12) NP_313073.1 similar to YJCD_ECOLI gi|1790499 (conserved in Escherichia coli K-12) NP_313074.1 similar to YJCE_ECOLI gi|1790501 (conserved in Escherichia coli K-12) NP_313075.1 similar to YJCF_ECOLI gi|1790502 (conserved in Escherichia coli K-12) NP_313076.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake NP_313077.1 similar to YJCH_ECOLI gi|1790504 (conserved in Escherichia coli K-12) NP_313078.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA NP_313079.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 NP_313080.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia NP_313081.1 similar to NRFC_ECOLI gi|2367345 (conserved in Escherichia coli K-12); formate-dependent nitrite reductase NP_313082.1 similar to NRFD_ECOLI gi|1790509 (conserved in Escherichia coli K-12) NP_313083.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 NP_313084.1 similar to NRFF_ECOLI gi|1790512 (conserved in Escherichia coli K-12) NP_313085.1 component of formate-dependent nitrite reductase complex; similar to NRFG_ECOLI gi|1790513 (conserved in Escherichia coli K-12) NP_313086.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system NP_313087.1 similar to YJCO_ECOLI gi|1790515 (conserved in Escherichia coli K-12) NP_313088.1 similar to FDHF_ECOLI gi|3868721 (conserved in Escherichia coli K-12) NP_313089.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family NP_313090.2 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride NP_313091.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride NP_313093.1 similar to YJCS_ECOLI gi|2367350 (conserved in Escherichia coli K-12) NP_313094.1 similar to regulatory proteins e.g. aerobic respiration control protein [Zymomonas mobilis] gi|4511977|gb|AAD21537.1| NP_313095.1 similar to sugar kinases e.g. fructokinase homolog ydjE [Bacillus subtilis] gi|3915420|sp|O34768|YDJE_BACSU NP_313096.1 similar to aldolases e.g. fructose-bisphosphate aldolase (EC 4.1.2.13) FbaA [Bacillus subtilis] gi|543796|sp|P13243|ALF1_BACSU NP_313097.1 similar to hypothetical protein ydaE [Bacillus subtilis] gi|7474928|pir||E69768 NP_313098.1 similar to carbohydrate binding protein, C-terminal part of bifunctional carbohydrate binding and transport protein Streptomyces coelicolor A3(2) CAB66286 NP_313099.1 similar to carbohydrate ABC transporters (permease) e.g. ribose ABC transporter (permease) rbsC [Bacillus subtilis] gi|7446897|pir||B69690 NP_313100.1 similar to sugar ABC transporter, ATP-binding proteins e.g. ribose ABC transporter (ATP-binding protein) rbsA [Bacillus subtilis] gi|7404442|sp|P36947|RBSA_BACSU NP_313101.1 similar to histidine protein kinases e.g. histidine protein kinase-response regulator hybrid protein CvgSY [Pseudomonas syringae pv. syringae] gi|5019771|gb|AAD37857.1|AF133263_2 NP_313102.1 required for the use of phosphonates and phosphite as phosphorus sources NP_313103.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role NP_313104.1 similar to PHNN_ECOLI gi|1790532 (conserved in Escherichia coli K-12) NP_313105.1 similar to PHNM_ECOLI gi|1790533 (conserved in Escherichia coli K-12) NP_313106.1 similar to PHNL_ECOLI gi|1790534 (conserved in Escherichia coli K-12) NP_313107.1 similar to PHNK_ECOLI gi|1790535 (conserved in Escherichia coli K-12) NP_313108.1 similar to PHNJ_ECOLI gi|1790536 (conserved in Escherichia coli K-12) NP_313109.1 similar to PHNI_ECOLI gi|1790537 (conserved in Escherichia coli K-12) NP_313110.1 similar to PHNH_ECOLI gi|1790538 (conserved in Escherichia coli K-12) NP_313111.1 similar to PHNG_ECOLI gi|1790539 (conserved in Escherichia coli K-12) NP_313112.1 may be involved in phosphonate uptake and biodegradation NP_313113.1 similar to PHNE_ECOLI (Strain B) SW: P16683, PHNE_ECOLI (strain K-12) gi|1790542, b4103_ECOLI (strain K-12) gi|179054 NP_313114.1 similar to PHND_ECOLI gi|1790543 (conserved in Escherichia coli K-12) NP_313115.1 similar to PHNC_ECOLI gi|1790544 (conserved in Escherichia coli K-12) NP_313116.1 similar to PHNB_ECOLI gi|1790546 (conserved in Escherichia coli K-12) NP_313117.1 similar to PHNA_ECOLI gi|1790547 (conserved in Escherichia coli K-12) NP_313118.1 similar to YJDA_ECOLI gi|1790548 (conserved in Escherichia coli K-12) NP_313119.2 similar to YJCZ_ECOLI gi|1790549 (conserved in Escherichia coli K-12) NP_313120.1 similar to PROP_ECOLI gi|1790550 (conserved in Escherichia coli K-12) NP_313121.1 similar to BASS_ECOLI gi|1790551 (conserved in Escherichia coli K-12) NP_313122.1 response regulator in two-component regulatory system with BasS NP_313123.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division NP_313124.1 similar to YJDE_ECOLI gi|2367353 (conserved in Escherichia coli K-12) NP_313125.1 similar to ADIY_ECOLI gi|1790557 (conserved in Escherichia coli K-12) NP_313126.1 similar to ADIA_ECOLI gi|1790558 (conserved in Escherichia coli K-12) NP_313127.1 similar to MELR_ECOLI gi|1790559 (conserved in Escherichia coli K-12) NP_313128.1 similar to MELA_ECOLI gi|1790560 (conserved in Escherichia coli K-12) NP_313129.1 similar to MELB_ECOLI gi|1790561 (conserved in Escherichia coli K-12) NP_313130.1 similar to YJDF_ECOLI gi|1790562 (conserved in Escherichia coli K-12) NP_313131.1 similar to FUMA_ECOLI gi|1787897 (conserved in Escherichia coli K-12) NP_313132.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters NP_313133.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration NP_313134.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration NP_313135.1 similar to YJDI_ECOLI gi|1790568 (conserved in Escherichia coli K-12) NP_313136.1 similar to YJDJ_ECOLI gi|1790569 (conserved in Escherichia coli K-12) NP_313137.1 similar to YJDK_ECOLI gi|1790570 (conserved in Escherichia coli K-12) NP_313138.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_313139.1 similar to YJDL_ECOLI gi|1790572 (conserved in Escherichia coli K-12) NP_313140.1 similar to CADA_ECOLI gi|1790573 (conserved in Escherichia coli K-12) NP_313141.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein NP_313142.1 regulates the cadBA operon NP_313143.1 similar to YJDC_ECOLI gi|1790577 (conserved in Escherichia coli K-12) NP_313144.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm NP_313145.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals NP_313146.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB NP_313147.2 catalyzes the formation of fumarate from aspartate NP_313148.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein NP_313149.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function NP_313150.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_313151.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_313152.1 similar to YJEI_ECOLI gi|1790587 (conserved in Escherichia coli K-12) NP_313153.1 similar to YJEJ_ECOLI gi|1790588 (conserved in Escherichia coli K-12) NP_313154.1 similar to YJEK_ECOLI gi|1790589 (conserved in Escherichia coli K-12) NP_313155.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_313156.1 similar to SUGE_ECOLI gi|1790591 (conserved in Escherichia coli K-12) NP_313157.1 lipocalin; globomycin-sensitive outer membrane lipoprotein NP_313158.1 similar to AMPC_ECOLI gi|1790593 (conserved in Escherichia coli K-12) NP_313159.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane NP_313160.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB NP_313161.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB NP_313162.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB NP_313163.2 lysine--tRNA ligase subunit beta; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA NP_313164.1 similar to YJEM_ECOLI gi|1790600 (conserved in Escherichia coli K-12) NP_313165.1 similar to YJEP_ECOLI gi|2367355 (conserved in Escherichia coli K-12) NP_313166.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine NP_313167.2 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity NP_313168.2 3'-5' exoribonuclease specific for small oligoribonuclotides NP_313169.1 similar to YJES_ECOLI gi|1790608 (conserved in Escherichia coli K-12) NP_313170.1 similar to YJEF_ECOLI gi|1790609 (conserved in Escherichia coli K-12) NP_313171.1 possibly involved in cell wall synthesis NP_313172.1 similar to AMIB_ECOLI gi|1790611 (conserved in Escherichia coli K-12) NP_313173.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex NP_313174.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_313175.1 Stimulates the elongation of poly(A) tails NP_313176.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein NP_313177.1 with HflC inhibits proteolysis of lambda cII protein by FtsH NP_313178.1 with HflK inhibits proteolysis of lambda cII protein by FtsH NP_313179.1 similar to YJET_ECOLI gi|1790619 (conserved in Escherichia coli K-12) NP_313180.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis NP_313181.1 negatively regulates the transcription of genes upregulated by nitrosative stress NP_313182.2 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs NP_313183.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA NP_313184.1 similar to YJFI_ECOLI gi|1790624 (conserved in Escherichia coli K-12) NP_313185.1 similar to YJFJ_ECOLI gi|1790625 (conserved in Escherichia coli K-12) NP_313186.1 similar to YJFK_ECOLI gi|1790626 (conserved in Escherichia coli K-12) NP_313187.1 similar to YJFL_ECOLI gi|1790627 (conserved in Escherichia coli K-12) NP_313188.1 similar to YJFM_ECOLI gi|1790628 (conserved in Escherichia coli K-12) NP_313189.1 similar to YJFC_ECOLI gi|1790629 (conserved in Escherichia coli K-12) NP_313190.3 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA NP_313191.2 similar to YJFN_ECOLI gi|1790631 (conserved in Escherichia coli K-12) NP_313192.2 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility NP_313193.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo NP_313194.1 negative regulator of ulaG and ulaABCDEF NP_313195.1 similar to YJFR_ECOLI gi|1790636 (conserved in Escherichia coli K-12) NP_313196.2 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr NP_313197.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake NP_313198.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake NP_313199.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization NP_313200.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway NP_313201.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source NP_313202.1 similar to YJFY_ECOLI gi|1790643 (conserved in Escherichia coli K-12) NP_313203.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_313204.1 binds single-stranded DNA at the primosome assembly site NP_313205.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_313206.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_313207.1 similar to YJFZ_ECOLI gi|1790648 (conserved in Escherichia coli K-12) NP_313208.1 similar to YTFA_ECOLI gi|1790650 NP_313209.1 TnpA of insertion sequence IS609; similar to transposase homolog A [Helicobacter pylori] gi|2114470|gb|AAD11513.1 NP_313210.2 TnpB of insertion sequence IS609; similar to B1432_ECOLI gi|1787702, transposases Xylella fastidiosa AAF83346 NP_313211.1 similar to YTFB_ECOLI gi|1790651 (conserved in Escherichia coli K-12) NP_313212.2 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides NP_313213.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine NP_313214.1 Involved in anaerobic NO protection and iron metabolism NP_313215.1 similar to YTFF_ECOLI gi|1790655 (conserved in Escherichia coli K-12) NP_313216.1 similar to YTFG_ECOLI gi|1790656 (conserved in Escherichia coli K-12) NP_313217.2 similar to YTFH_ECOLI gi|1790657 (conserved in Escherichia coli K-12) NP_313218.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate NP_313219.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate NP_313220.1 similar to YTFI_ECOLI gi|1790661 NP_313221.1 similar to YTFJ_ECOLI gi|1790662 (conserved in Escherichia coli K-12) NP_313222.1 similar to YTFK_ECOLI gi|1790663 (conserved in Escherichia coli K-12) NP_313223.1 similar to YTFL_ECOLI gi|1790664 (conserved in Escherichia coli K-12) NP_313224.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress NP_313225.1 similar to YTFM_ECOLI gi|1790666 (conserved in Escherichia coli K-12) NP_313226.1 similar to YTFN_ECOLI gi|1790667 (conserved in Escherichia coli K-12) NP_313227.1 similar to YTFP_ECOLI gi|1790668 (conserved in Escherichia coli K-12) NP_313228.1 similar to YJFA_ECOLI gi|1790669 (conserved in Escherichia coli K-12) NP_313229.1 part of the toxin-antitoxin ChpB-ChpS system NP_313230.1 toxin of the ChpB-ChpS toxin-antitoxin system NP_313231.1 catalyzes the hydrolysis of pyrophosphate to phosphate NP_313232.1 similar to YTFQ_ECOLI gi|1790674 (conserved in Escherichia coli K-12) NP_313233.1 similar to YTFR_ECOLI gi|1790675, YTFS_ECOLI gi|1790676 NP_313234.1 similar to YTFT_ECOLI gi|1790677 (conserved in Escherichia coli K-12) NP_313235.1 membrane component of a sugar ABC transporter system NP_313236.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate NP_313237.1 similar to YJFG_ECOLI gi|1790680 (conserved in Escherichia coli K-12) NP_313238.1 similar to YJGA_ECOLI gi|1790681 (conserved in Escherichia coli K-12) NP_313239.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD NP_313240.2 similar to CYBC_ECOLI gi|1790684 (conserved in Escherichia coli K-12) NP_313241.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions NP_313242.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates NP_313243.1 similar to TREC_ECOLI gi|1790687 (conserved in Escherichia coli K-12) NP_313244.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel NP_313245.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon NP_313246.1 P-type ATPase involved in magnesium influx NP_313247.1 similar to YJGF_ECOLI gi|1790691 (conserved in Escherichia coli K-12) NP_313248.1 involved in the allosteric regulation of aspartate carbamoyltransferase NP_313249.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis NP_313250.1 similar to PYRL_ECOLI gi|1790694 (conserved in Escherichia coli K-12) NP_313252.1 similar to YJGH_ECOLI gi|1790696 (conserved in Escherichia coli K-12) NP_313253.1 similar to YJGI_ECOLI gi|2367365 (conserved in Escherichia coli K-12) NP_313255.2 similar to YJGJ_ECOLI gi|1790700 (conserved in Escherichia coli K-12) NP_313256.2 similar to YJGK_ECOLI gi|1790701 (conserved in Escherichia coli K-12) NP_313257.1 similar to YJGL_ECOLI gi|1790702 NP_313258.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. NP_313259.1 similar to YJGD_ECOLI gi|1790704 (conserved in Escherichia coli K-12) NP_313260.2 similar to B4256_ECOLI gi|1790705 (conserved in Escherichia coli K-12) NP_313261.1 similar to YJGN_ECOLI gi|2367367 (conserved in Escherichia coli K-12) NP_313262.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_313263.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB NP_313264.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_313265.1 similar to YJGP_ECOLI gi|1790712 (conserved in Escherichia coli K-12) NP_313266.2 similar to YJGQ_ECOLI gi|1790713 (conserved in Escherichia coli K-12) NP_313267.1 similar to YJGR_ECOLI gi|1790714 (conserved in Escherichia coli K-12) NP_313268.2 similar to YJGB_ECOLI gi|1790720 (conserved in Escherichia coli K-12) NP_313269.1 similar to integrases e.g. integrase [Bacteriophage TPW22] gi|6465906|gb|AAF12706.1|AF066865_4 NP_313270.1 OrfA protein of insertion sequence IS629; similar to gi|7444868|pir||T00241 NP_313271.1 OrfB protein of insertion sequence IS629; similar to [Escherichia coli plasmid pO157] gi|7443862|pir||T00240 NP_313275.1 similar to hypothetical proteins [Staphylococcus aureus] e.g. gi|7594765|dbj|BAA94663.1|, hypothetical proteins [Neisseria meningitidis] gi|5051461|emb|CAB44981.1| NP_313276.1 similar to resolvases e.g. resolvase [Escherichia coli transposon Tn2501] gi|135944|sp|P05823|TNP0_ECOLI NP_313279.1 similar to transcription regulators e.g. BamH I control element [Bacillus amyloliquefaciens] gi|116073|sp|P23939|CEBA_BACAM NP_313280.1 similar to integrases e.g. [prophage P4] gi|732036|sp|P39347|INTB_ECOLI NP_313282.1 similar to hypothetical proteins e.g. YjH [Escherichia coli] gi|7404491|sp|P39371|YJHT_ECOLI NP_313284.1 similar to periplasmic protein [Campylobacter jejuni]gi|6968066|emb|CAB75235.1| NP_313285.1 similar to myosin heavy chains e.g. [Cyprinus carpio] gi|2351223|dbj|BAA22069.1| NP_313286.1 similar to YjiT [Escherichia coli] gi|732099|sp|P39391|YJIT_ECOLI NP_313287.1 similar to probable RNA helicase Deinococcus radiodurans strain R1 B75633, hypothetical YjiV protein Escherichia coli NP_313288.1 similar to ATP-dependent helicases e.g. [Halobacterium sp. (strain NRC-1) plasmid pNRC100] gi|7484100|pir||T08316 NP_313289.1 similar to hypothetical proteins e.g. H1130 [Halobacterium sp. (strain NRC-1) plasmid pNRC100] gi|7484076|pir||T08313, restriction /modification enzyme [Campylobacter jejuni] gi|6968147|e NP_313290.1 probable RNA helicase, similar to probable RNA helicases e.g. [Deinococcus radiodurans (strain R1)] gi|7473663|pir||B75633 NP_313291.1 similar to DNA helicases e.g. probable DNA helicase H91_ORF529 [Mycoplasma pneumoniae] gi|2495150|sp|P75438|YH91_MYCPN, helicase IV [Escherichia coli] gi|146328|gb|AAA23952.1| NP_313292.1 similar to hypothetical protein YchG [Escherichia coli] gi|267475|sp|P30192|YCHG_ECOLI NP_313293.1 similar to hypothetical proteins e.g. YchG [Escherichia coli] gi|267475|sp|P30192|YCHG_ECOLI NP_313294.1 similar to hypothetical protein b1240 [Escherichia coli] gi|7466155|pir||C64871 NP_313295.1 similar to YJHS_ECOLI gi|1790763 (conserved in Escherichia coli K-12) NP_313296.1 similar to YJHT_ECOLI gi|1790764 (conserved in Escherichia coli K-12) NP_313297.2 similar to YJHA_ECOLI gi|1790765 (conserved in Escherichia coli K-12) NP_313298.1 inversion of on/off regulator of fimA NP_313299.1 inversion of on/off regulator of fimA NP_313300.1 similar to FIMA_ECOLI gi|1790769 (conserved in Escherichia coli K-12); major type 1 subunit fimbrin NP_313301.1 fimbrial protein; similar to FIMI_ECOLI gi|1790770 (conserved in Escherichia coli K-12) NP_313302.2 periplasmic chaperone required for type 1 fimbriae; similar to FIMC_ECOLI gi|1790771 (conserved in Escherichia coli K-12) NP_313303.1 similar to FIMD_ECOLI gi|1790772 (conserved in Escherichia coli K-12) NP_313304.1 similar to FIMF_ECOLI gi|1790773 (conserved in Escherichia coli K-12) NP_313305.1 similar to FIMG_ECOLI gi|1790774 (conserved in Escherichia coli K-12) NP_313306.1 similar to FIMH_ECOLI gi|1790775 (conserved in Escherichia coli K-12); FimH; minor fimbrial subunit NP_313307.1 similar to GNTP_ECOLI gi|1790776 (conserved in Escherichia coli K-12) NP_313308.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate NP_313309.1 similar to UXUB_ECOLI gi|1790779 (conserved in Escherichia coli K-12) NP_313310.1 regulates the expression of uxuBA NP_313311.2 similar to YJIC_ECOLI gi|1790781 (conserved in Escherichia coli K-12) NP_313312.2 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS NP_313313.1 similar to IADA_ECOLI gi|1790784 (conserved in Escherichia coli K-12) NP_313314.1 similar to YJIG_ECOLI gi|1790785 (conserved in Escherichia coli K-12) NP_313315.1 similar to YJIH_ECOLI gi|1790786 (conserved in Escherichia coli K-12) NP_313316.2 similar to N-terminal part of YJII_ECOLI gi|1790787 NP_313317.1 similar toinvasin [Yersinia pseudotuberculosis] gi|79202|pir||A29646, probable membrane protein b1978 [Escherichia coli K-12] gi|1736642|dbj|BAA15799.1| NP_313319.1 similar to probable membrane protein b1978 [Escherichia coli K-12] gi|1736642|dbj|BAA15799.1| NP_313320.1 similar to YJIJ_ECOLI gi|1790788 (conserved in Escherichia coli K-12) NP_313321.1 similar to YJIK_ECOLI gi|1790790 (conserved in Escherichia coli K-12) NP_313324.1 similar to YJIL_ECOLI gi|1790791 (conserved in Escherichia coli K-12) NP_313325.2 similar to YJIM_ECOLI gi|1790792 (conserved in Escherichia coli K-12) NP_313326.1 similar to YJIN_ECOLI gi|1790793 (conserved in Escherichia coli K-12) NP_313327.1 similar to YJIO_ECOLI gi|1790794 (conserved in Escherichia coli K-12) NP_313328.1 similar to YJIP_ECOLI gi|1790795, YJIQ_ECOLI gi|1790796 NP_313329.1 similar to YJIR_ECOLI gi|1790797 (conserved in Escherichia coli K-12) NP_313330.1 similar to YJIS_ECOLI gi|1790798 (conserved in Escherichia coli K-12) NP_313331.1 similar to hypothetical proteins e.g. jhp0462 [Helicobacter pylori (strain J99)] gi|7464730|pir||C71929, jhp0572 [Helicobacter pylori (strain J99)] gi|7464757|pir||H71914 NP_313332.1 similar to hypothetical protein e.g. jhp0462 [Helicobacter pylori (strain J99)] gi|7464730|pir||C71929, HP0513 [Helicobacter pylori (strain 26695)] gi|7464291|pir||A64584 NP_944586.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response NP_313333.1 type I restriction-modification enzyme S subunits e.g. [Citrobacter freundii] pir|S06097| NP_313334.1 similar to type I restriction modification enzyme M subunits e.g. [EcoA system] gi|421016|pir||A47200 NP_313335.1 similar to type I restriction-modification enzyme R subunits e.g. [EcoA] gi|2121113|pir||I41291 NP_313336.1 similar to hypothetical proteins e.g. [Helicobacter pylori] gi|7464531|pir||E64694 NP_313337.1 similar to hypothetical protein [Streptomyces coelicolor A3(2)] gi|7479715|pir||T35601 NP_313338.2 similar to YJIA_ECOLI gi|1790812 (conserved in Escherichia coli K-12) NP_313339.1 similar to YJIX_ECOLI gi|1790813 (conserved in Escherichia coli K-12) NP_313340.1 similar to YJIY_ECOLI gi|1790814 (conserved in Escherichia coli K-12) NP_313342.1 similar to TSR_ECOLI gi|2367378 (conserved in Escherichia coli K-12) NP_313343.1 similar to YJIZ_ECOLI gi|2367379 (conserved in Escherichia coli K-12) NP_313344.1 similar to YJJM_ECOLI gi|1790818 (conserved in Escherichia coli K-12) NP_313345.1 similar to YJJN_ECOLI gi|1790819 (conserved in Escherichia coli K-12) NP_313346.2 catalyzes the transfer of phosphoglycerol to the glucan backbone NP_313347.1 similar to YJJA_ECOLI gi|1790822 (conserved in Escherichia coli K-12) NP_313348.1 acts to load the DnaB helicase onto the initiation site during DNA replication NP_313349.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' NP_313350.2 similar to YJJB_ECOLI gi|1790825 (conserved in Escherichia coli K-12) NP_313351.2 similar to YJJP_ECOLI gi|1790826 (conserved in Escherichia coli K-12) NP_313352.1 similar to YJJQ_ECOLI gi|1790827 (conserved in Escherichia coli K-12) NP_313353.2 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin NP_313354.1 similar to FHUF_ECOLI gi|1790829 (conserved in Escherichia coli K-12) NP_313355.2 similar to YJJZ_ECOLI gi|2495668|sp|P55914 (conserved in Escherichia coli K-12) NP_313356.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit NP_313357.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB NP_313358.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 NP_313359.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily NP_313360.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein NP_313361.1 similar to OSMY_ECOLI gi|1790836 (conserved in Escherichia coli K-12) NP_313362.1 similar to YJJU_ECOLI gi|1790837 (conserved in Escherichia coli K-12) NP_313363.1 similar to YJJV_ECOLI gi|1790838 NP_313364.1 similar to YJJW_ECOLI gi|1790839 (conserved in Escherichia coli K-12) NP_313367.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate NP_313368.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate NP_313369.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose NP_313370.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate NP_313372.1 in E. coli the lipoate ligase A catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes; creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins NP_313373.1 catalyzes the formation of serine from O-phosphoserine NP_313374.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_313375.2 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide NP_313376.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence NP_313377.2 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan NP_313378.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription NP_313379.2 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog NP_313380.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate NP_313381.1 similar to ROB_ECOLI gi|1790857 (conserved in Escherichia coli K-12) NP_313382.1 similar to CREA_ECOLI gi|1790859 (conserved in Escherichia coli K-12) NP_313383.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation NP_313384.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation NP_313385.1 similar to CRED_ECOLI gi|1790862 (conserved in Escherichia coli K-12) NP_313386.1 similar to ARCA_ECOLI gi|1790863 (conserved in Escherichia coli K-12) NP_313387.1 similar to YJJY_ECOLI gi|1790864 (conserved in Escherichia coli K-12) NP_313388.1 member of the SPOUT superfamily of methyltransferases