-- dump date 20140619_091055 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002381183.1 218454960 7169423 250..1251 1 NC_011739.1 PI protein (Replication initiation protein) 1251 7169423 p2ECUMN_0001 Escherichia coli UMN026 PI protein (Replication initiation protein) YP_002381183.1 250 D 585056 CDS YP_002381184.1 218454961 7169448 1260..1703 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; Hypothetical protein; putative membrane protein 1703 7169448 p2ECUMN_0002 Escherichia coli UMN026 Hypothetical protein; putative membrane protein YP_002381184.1 1260 D 585056 CDS YP_002381185.1 218454962 7169461 1722..2186 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2186 7169461 p2ECUMN_0003 Escherichia coli UMN026 hypothetical protein YP_002381185.1 1722 D 585056 CDS YP_002381186.1 218454963 7169459 complement(2569..2784) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane protein 2784 7169459 p2ECUMN_0004 Escherichia coli UMN026 hypothetical protein, putative membrane protein YP_002381186.1 2569 R 585056 CDS YP_002381187.1 218454964 7169457 complement(2935..3216) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative membrane protein 3216 7169457 p2ECUMN_0005 Escherichia coli UMN026 hypothetical protein; putative membrane protein YP_002381187.1 2935 R 585056 CDS YP_002381188.1 218454965 7169449 complement(3378..3662) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane protein 3662 7169449 p2ECUMN_0006 Escherichia coli UMN026 hypothetical protein, putative membrane protein YP_002381188.1 3378 R 585056 CDS YP_002381189.1 218454966 7169467 complement(3699..4046) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative Methionine repressor-like protein 4046 7169467 p2ECUMN_0007 Escherichia coli UMN026 hypothetical protein, putative Methionine repressor-like protein YP_002381189.1 3699 R 585056 CDS YP_002381190.1 218454967 7169450 complement(4095..4757) 1 NC_011739.1 putative YafB protein 4757 7169450 p2ECUMN_0008 Escherichia coli UMN026 putative YafB protein YP_002381190.1 4095 R 585056 CDS YP_002381191.1 218454968 7169458 complement(4869..5759) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative resolvase (Protein D) 5759 7169458 p2ECUMN_0009 Escherichia coli UMN026 putative resolvase (Protein D) YP_002381191.1 4869 R 585056 CDS YP_002381192.1 218454969 7169447 complement(6240..6896) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein; putative exported protein 6896 7169447 p2ECUMN_0010 Escherichia coli UMN026 conserved hypothetical protein; putative exported protein YP_002381192.1 6240 R 585056 CDS YP_002381193.1 218454970 7169465 complement(7000..7464) 1 NC_011739.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; global nucleic acid-binding transcriptional dual regulator 7464 hns 7169465 hns Escherichia coli UMN026 global nucleic acid-binding transcriptional dual regulator YP_002381193.1 7000 R 585056 CDS YP_002381194.1 218454971 7169470 complement(7482..7688) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; Conserved hypothetical protein, putative haemolysin expression modulating protein 7688 7169470 p2ECUMN_0012 Escherichia coli UMN026 Conserved hypothetical protein, putative haemolysin expression modulating protein YP_002381194.1 7482 R 585056 CDS YP_002381195.1 218454972 7169464 complement(7685..9838) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA topoisomerase III 9838 7169464 p2ECUMN_0013 Escherichia coli UMN026 putative DNA topoisomerase III YP_002381195.1 7685 R 585056 CDS YP_002381196.1 218454973 7169451 complement(9850..10467) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 10467 7169451 p2ECUMN_0014 Escherichia coli UMN026 hypothetical protein YP_002381196.1 9850 R 585056 CDS YP_002381197.1 218454974 7169460 complement(10464..10784) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 10784 7169460 p2ECUMN_0015 Escherichia coli UMN026 hypothetical protein YP_002381197.1 10464 R 585056 CDS YP_002381198.1 218454975 7169463 complement(10844..11248) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 11248 7169463 p2ECUMN_0016 Escherichia coli UMN026 hypothetical protein YP_002381198.1 10844 R 585056 CDS YP_002381199.1 218454976 7169452 complement(11264..11779) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endonuclease precursor 11779 7169452 p2ECUMN_0017 Escherichia coli UMN026 putative endonuclease precursor YP_002381199.1 11264 R 585056 CDS YP_002381200.1 218454977 7169462 complement(11776..12210) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative exported protein, putative membrane protein 12210 7169462 p2ECUMN_0018 Escherichia coli UMN026 hypothetical protein; putative exported protein, putative membrane protein YP_002381200.1 11776 R 585056 CDS YP_002381201.1 218454978 7169453 complement(12292..12549) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 12549 7169453 p2ECUMN_0019 Escherichia coli UMN026 hypothetical protein YP_002381201.1 12292 R 585056 CDS YP_002381202.1 218454979 7169454 complement(12555..12857) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein, putative plasmid conjugation protein kikA, putative exported protein 12857 7169454 p2ECUMN_0020 Escherichia coli UMN026 conserved hypothetical protein, putative plasmid conjugation protein kikA, putative exported protein YP_002381202.1 12555 R 585056 CDS YP_002381203.1 218454980 7169455 complement(12854..13267) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein; putative exported protein, putative VirB/Tra/Trw family protein 13267 7169455 p2ECUMN_0021 Escherichia coli UMN026 conserved hypothetical protein; putative exported protein, putative VirB/Tra/Trw family protein YP_002381203.1 12854 R 585056 CDS YP_002381204.1 218454981 7169456 complement(13264..15105) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; Hypothetical protein, putative TraG/TraD family protein, putative membrane protein 15105 7169456 p2ECUMN_0022 Escherichia coli UMN026 Hypothetical protein, putative TraG/TraD family protein, putative membrane protein YP_002381204.1 13264 R 585056 CDS YP_002381205.1 218454982 7169469 complement(15102..16133) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative protein virB11, putative Type II/IV secretion system protein 16133 7169469 p2ECUMN_0023 Escherichia coli UMN026 Putative protein virB11, putative Type II/IV secretion system protein YP_002381205.1 15102 R 585056 CDS YP_002381206.1 218454983 7169468 complement(16135..17340) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx10 protein, putative bacterial conjugation TrbI-like protein 17340 7169468 p2ECUMN_0024 Escherichia coli UMN026 Putative pilx10 protein, putative bacterial conjugation TrbI-like protein YP_002381206.1 16135 R 585056 CDS YP_002381207.1 218454984 7169466 complement(17337..18266) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx9 protein, putative conjugal transfer protein, putative exported protein 18266 7169466 p2ECUMN_0025 Escherichia coli UMN026 Putative pilx9 protein, putative conjugal transfer protein, putative exported protein YP_002381207.1 17337 R 585056 CDS YP_002381208.1 218454985 7169422 complement(18271..18984) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative pilx8 protein 18984 7169422 p2ECUMN_0026 Escherichia coli UMN026 Putative pilx8 protein YP_002381208.1 18271 R 585056 CDS YP_002381209.1 218454986 7169424 complement(19229..20362) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative TrbL/VirB6 plasmid conjugal transfer protein 20362 7169424 p2ECUMN_0027 Escherichia coli UMN026 Putative TrbL/VirB6 plasmid conjugal transfer protein YP_002381209.1 19229 R 585056 CDS YP_002381210.1 218454987 7169444 complement(20372..20599) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein; putative exported protein 20599 7169444 p2ECUMN_0028 Escherichia coli UMN026 hypothetical protein; putative exported protein YP_002381210.1 20372 R 585056 CDS YP_002381211.1 218454988 7169443 complement(20600..21358) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx5/VirB5 protein, putative conjugal transfer protein, putative exported protein 21358 7169443 p2ECUMN_0029 Escherichia coli UMN026 putative Pilx5/VirB5 protein, putative conjugal transfer protein, putative exported protein YP_002381211.1 20600 R 585056 CDS YP_002381212.1 218454989 7169442 complement(21369..24122) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx3-4/VirB3-4 protein, putative conjugal transfer protein 24122 7169442 p2ECUMN_0030 Escherichia coli UMN026 putative Pilx3-4/VirB3-4 protein, putative conjugal transfer protein YP_002381212.1 21369 R 585056 CDS YP_002381213.1 218454990 7169441 complement(24144..24473) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; Putative Pilx2 protein 24473 7169441 p2ECUMN_0031 Escherichia coli UMN026 Putative Pilx2 protein YP_002381213.1 24144 R 585056 CDS YP_002381214.1 218454991 7169440 complement(24418..25065) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative Pilx1/VirB1 protein, putative conjugal transfer protein, putative exported protein 25065 7169440 p2ECUMN_0032 Escherichia coli UMN026 putative Pilx1/VirB1 protein, putative conjugal transfer protein, putative exported protein YP_002381214.1 24418 R 585056 CDS YP_002381215.1 218454992 7169439 complement(25111..25332) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 25332 7169439 p2ECUMN_0033 Escherichia coli UMN026 hypothetical protein YP_002381215.1 25111 R 585056 CDS YP_002381216.1 218454993 7169438 complement(25802..25975) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 25975 7169438 p2ECUMN_0034 Escherichia coli UMN026 hypothetical protein YP_002381216.1 25802 R 585056 CDS YP_002381217.1 218454994 7169437 complement(26122..27294) 1 NC_011739.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Nickase 27294 taxC 7169437 taxC Escherichia coli UMN026 Nickase YP_002381217.1 26122 R 585056 CDS YP_002381218.1 218454995 7169445 complement(27291..27938) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 27938 7169445 p2ECUMN_0036 Escherichia coli UMN026 hypothetical protein YP_002381218.1 27291 R 585056 CDS YP_002381219.1 218454996 7169436 complement(27942..28091) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 28091 7169436 p2ECUMN_0037 Escherichia coli UMN026 hypothetical protein YP_002381219.1 27942 R 585056 CDS YP_002381220.1 218454997 7169435 complement(28152..28424) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 28424 7169435 p2ECUMN_0038 Escherichia coli UMN026 hypothetical protein YP_002381220.1 28152 R 585056 CDS YP_002381221.1 218454998 7169434 complement(28437..28634) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 28634 7169434 p2ECUMN_0039 Escherichia coli UMN026 hypothetical protein YP_002381221.1 28437 R 585056 CDS YP_002381222.1 218454999 7169433 complement(28655..28966) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 28966 7169433 p2ECUMN_0040 Escherichia coli UMN026 hypothetical protein YP_002381222.1 28655 R 585056 CDS YP_002381223.1 218455000 7169432 complement(28963..29379) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 29379 7169432 p2ECUMN_0041 Escherichia coli UMN026 hypothetical protein YP_002381223.1 28963 R 585056 CDS YP_002381224.1 218455001 7169431 complement(29389..29730) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative GMP synthase 29730 7169431 p2ECUMN_0042 Escherichia coli UMN026 hypothetical protein, putative GMP synthase YP_002381224.1 29389 R 585056 CDS YP_002381225.1 218455002 7169430 complement(29690..30049) 1 NC_011739.1 Evidence 6 : Doubtful CDS; hypothetical protein 30049 7169430 p2ECUMN_0043 Escherichia coli UMN026 hypothetical protein YP_002381225.1 29690 R 585056 CDS YP_002381226.1 218455003 7169429 complement(30142..30369) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative YajA protein, putative regulator 30369 7169429 p2ECUMN_0045 Escherichia coli UMN026 putative YajA protein, putative regulator YP_002381226.1 30142 R 585056 CDS YP_002381227.1 218455004 7169428 complement(30356..30607) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 30607 7169428 p2ECUMN_0046 Escherichia coli UMN026 hypothetical protein YP_002381227.1 30356 R 585056 CDS YP_002381228.1 218455005 7169427 complement(30604..31146) 1 NC_011739.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 31146 7169427 p2ECUMN_0047 Escherichia coli UMN026 hypothetical protein YP_002381228.1 30604 R 585056 CDS YP_002381229.1 218455006 7169426 complement(31251..32129) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative DnaJ-class molecular chaperone 32129 7169426 p2ECUMN_0048 Escherichia coli UMN026 putative DnaJ-class molecular chaperone YP_002381229.1 31251 R 585056 CDS YP_002381230.1 218455007 7169425 complement(32406..32756) 1 NC_011739.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 32756 7169425 p2ECUMN_0049 Escherichia coli UMN026 putative transcriptional regulator YP_002381230.1 32406 R 585056 CDS YP_002381231.1 218455008 7169446 complement(32753..33088) 1 NC_011739.1 Evidence 4 : Homologs of previously reported genes of unknown function; conserved hypothetical protein, putative phage origin 33088 7169446 p2ECUMN_0050 Escherichia coli UMN026 conserved hypothetical protein, putative phage origin YP_002381231.1 32753 R 585056 CDS YP_002405907.1 218692795 7144300 101..1078 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8356112, 2651415, 8320218; Product type r : regulator; replication protein 1078 RepFIB 7144300 RepFIB Escherichia coli UMN026 replication protein YP_002405907.1 101 D 585056 CDS YP_002405908.1 218692796 7144240 complement(1321..2061) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; site-specific recombinase 2061 int 7144240 int Escherichia coli UMN026 site-specific recombinase YP_002405908.1 1321 R 585056 CDS YP_002405909.1 218692797 7144229 2737..3906 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3906 7144229 p1ECUMN_0003 Escherichia coli UMN026 hypothetical protein YP_002405909.1 2737 D 585056 CDS YP_002405910.1 218692798 7144302 complement(5621..6031) 1 NC_011749.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; hypothetical protein 6031 insC 7144302 insC Escherichia coli UMN026 hypothetical protein YP_002405910.1 5621 R 585056 CDS YP_002405911.1 218692799 7144227 6268..8238 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11179376, 7768795, 9393841, 9680204, 9157252; Product type prc : receptor; Hemin receptor precursor 8238 7144227 p1ECUMN_0005 Escherichia coli UMN026 Hemin receptor precursor YP_002405911.1 6268 D 585056 CDS YP_002405912.1 218692800 7144303 8245..9036 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 9036 7144303 p1ECUMN_0006 Escherichia coli UMN026 hypothetical protein YP_002405912.1 8245 D 585056 CDS YP_002405913.1 218692801 7144304 complement(9099..9617) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; transposase 9617 7144304 p1ECUMN_0007 Escherichia coli UMN026 transposase YP_002405913.1 9099 R 585056 CDS YP_002405914.1 218692802 7144305 complement(9775..10557) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase/IS protein 10557 7144305 p1ECUMN_0008 Escherichia coli UMN026 transposase/IS protein YP_002405914.1 9775 R 585056 CDS YP_002405915.1 218692803 7144306 complement(10554..11576) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2 IS100 11576 7144306 p1ECUMN_0009 Escherichia coli UMN026 transposase ORF2 IS100 YP_002405915.1 10554 R 585056 CDS YP_002405916.1 218692804 7144307 complement(11590..12348) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fragment of transposase ORF2, ISEc8, IS66 family 12348 7144307 p1ECUMN_0010 Escherichia coli UMN026 fragment of transposase ORF2, ISEc8, IS66 family YP_002405916.1 11590 R 585056 CDS YP_002405917.1 218692805 7144308 complement(12350..12607) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase IS66 family (part 1) 12607 7144308 p1ECUMN_0011 Escherichia coli UMN026 transposase IS66 family (part 1) YP_002405917.1 12350 R 585056 CDS YP_002405918.1 218692806 7144309 complement(12656..13003) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2, ISEc8, IS66 family 13003 7144309 p1ECUMN_0012 Escherichia coli UMN026 transposase ORF2, ISEc8, IS66 family YP_002405918.1 12656 R 585056 CDS YP_002405919.1 218692807 7144310 complement(13000..13404) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF 1, ISEc8, IS66 family 13404 7144310 p1ECUMN_0013 Escherichia coli UMN026 transposase ORF 1, ISEc8, IS66 family YP_002405919.1 13000 R 585056 CDS YP_002405920.1 218692808 7144312 complement(13906..15429) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; reverse transcriptase-like protein from prophage or plasmid 15429 7144312 p1ECUMN_0015 Escherichia coli UMN026 reverse transcriptase-like protein from prophage or plasmid YP_002405920.1 13906 R 585056 CDS YP_002405921.1 218692809 7144316 complement(17680..18954) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; Enterotoxin TieB protein 18954 senB 7144316 senB Escherichia coli UMN026 Enterotoxin TieB protein YP_002405921.1 17680 R 585056 CDS YP_002405922.1 218692810 7144245 complement(18924..21185) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11395459; Product type rc : receptor; outer membrane colicin Js receptor 21185 CjrC 7144245 CjrC Escherichia coli UMN026 outer membrane colicin Js receptor YP_002405922.1 18924 R 585056 CDS YP_002405923.1 218692811 7144212 complement(21354..22130) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11395459; Product type rc : receptor; periplasmic colicin Js sensitivity protein 22130 CjrB 7144212 CjrB Escherichia coli UMN026 periplasmic colicin Js sensitivity protein YP_002405923.1 21354 R 585056 CDS YP_002405924.1 218692812 7144211 complement(22138..23055) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11395459; iron-regulated protein cjrA 23055 7144211 p1ECUMN_0022 Escherichia coli UMN026 iron-regulated protein cjrA YP_002405924.1 22138 R 585056 CDS YP_002405925.1 218692813 7144317 complement(23345..23605) 1 NC_011749.1 hypothetical protein 23605 7144317 p1ECUMN_0023 Escherichia coli UMN026 hypothetical protein YP_002405925.1 23345 R 585056 CDS YP_002405926.1 218692814 7144318 complement(23602..23892) 1 NC_011749.1 Rep protein (fragment) 23892 7144318 p1ECUMN_0024 Escherichia coli UMN026 Rep protein (fragment) YP_002405926.1 23602 R 585056 CDS YP_002405927.1 218692815 7144319 25237..25446 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 25446 7144319 p1ECUMN_0025 Escherichia coli UMN026 hypothetical protein YP_002405927.1 25237 D 585056 CDS YP_002405928.1 218692816 7144320 complement(25464..25799) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3531169, 7972047; Product type m : membrane component; Colicin-Ia immunity protein 25799 imm 7144320 imm Escherichia coli UMN026 Colicin-Ia immunity protein YP_002405928.1 25464 R 585056 CDS YP_002405929.1 218692817 7144217 complement(25777..25995) 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 25995 7144217 p1ECUMN_0027 Escherichia coli UMN026 hypothetical protein YP_002405929.1 25777 R 585056 CDS YP_002405930.1 218692818 7144321 25928..26275 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 26275 ybaA 7144321 ybaA Escherichia coli UMN026 hypothetical protein YP_002405930.1 25928 D 585056 CDS YP_002405931.1 218692819 7144283 complement(26295..26804) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 26804 7144283 p1ECUMN_0029 Escherichia coli UMN026 hypothetical protein YP_002405931.1 26295 R 585056 CDS YP_002405932.1 218692820 7144322 complement(26801..27061) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 27061 ydfA 7144322 ydfA Escherichia coli UMN026 hypothetical protein YP_002405932.1 26801 R 585056 CDS YP_002405933.1 218692821 7144289 27163..27489 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS629 27489 7144289 p1ECUMN_0031 Escherichia coli UMN026 transposase IS629 YP_002405933.1 27163 D 585056 CDS YP_002405934.1 218692822 7144324 28560..29063 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; transposase 29063 7144324 p1ECUMN_0033 Escherichia coli UMN026 transposase YP_002405934.1 28560 D 585056 CDS YP_002405935.1 218692823 7144325 complement(29102..29701) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 29701 7144325 p1ECUMN_0034 Escherichia coli UMN026 hypothetical protein YP_002405935.1 29102 R 585056 CDS YP_002405936.1 218692824 7144326 complement(29397..29846) 1 NC_011749.1 glucose-1-phosphatase precursor 29846 7144326 p1ECUMN_0035 Escherichia coli UMN026 glucose-1-phosphatase precursor YP_002405936.1 29397 R 585056 CDS YP_002405937.1 218692825 7144327 complement(29968..30453) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 30453 7144327 p1ECUMN_0036 Escherichia coli UMN026 hypothetical protein YP_002405937.1 29968 R 585056 CDS YP_002405938.1 218692826 7144328 complement(30478..31032) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin-family protein 31032 7144328 p1ECUMN_0037 Escherichia coli UMN026 thioredoxin-family protein YP_002405938.1 30478 R 585056 CDS YP_002405939.1 218692827 7144329 complement(30950..31645) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; ABC transporter ATP-binding protein 31645 7144329 p1ECUMN_0038 Escherichia coli UMN026 ABC transporter ATP-binding protein YP_002405939.1 30950 R 585056 CDS YP_002405940.1 218692828 7144330 complement(31650..32810) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 32810 7144330 p1ECUMN_0039 Escherichia coli UMN026 hypothetical protein YP_002405940.1 31650 R 585056 CDS YP_002405941.1 218692829 7144331 complement(32770..34053) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 34053 7144331 p1ECUMN_0040 Escherichia coli UMN026 hypothetical protein YP_002405941.1 32770 R 585056 CDS YP_002405942.1 218692830 7144332 complement(34056..35435) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 35435 7144332 p1ECUMN_0041 Escherichia coli UMN026 hypothetical protein YP_002405942.1 34056 R 585056 CDS YP_002405943.1 218692831 7144333 complement(35539..36069) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 36069 7144333 p1ECUMN_0042 Escherichia coli UMN026 hypothetical protein YP_002405943.1 35539 R 585056 CDS YP_002405944.1 218692832 7144334 complement(36107..38053) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 38053 7144334 p1ECUMN_0043 Escherichia coli UMN026 hypothetical protein YP_002405944.1 36107 R 585056 CDS YP_002405945.1 218692833 7144335 complement(38340..39155) 1 NC_011749.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 39155 7144335 p1ECUMN_0045 Escherichia coli UMN026 Na(+)-translocating NADH-quinone reductase subunit C YP_002405945.1 38340 R 585056 CDS YP_002405946.1 218692834 7144336 complement(39338..39844) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; copper-sensitivity suppressor D 39844 scsD 7144336 scsD Escherichia coli UMN026 copper-sensitivity suppressor D YP_002405946.1 39338 R 585056 CDS YP_002405947.1 218692835 7144244 complement(39834..40061) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; copper-sensitivity suppressor C 40061 scsC 7144244 scsC Escherichia coli UMN026 copper-sensitivity suppressor C YP_002405947.1 39834 R 585056 CDS YP_002405948.1 218692836 7144243 complement(40142..40294) 1 NC_011749.1 Evidence 7 : Gene remnant; Product type e : enzyme; transposase IS26 fragment 40294 7144243 p1ECUMN_0048 Escherichia coli UMN026 transposase IS26 fragment YP_002405948.1 40142 R 585056 CDS YP_002405949.1 218692837 7144242 40455..40730 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 40730 insA 7144242 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002405949.1 40455 D 585056 CDS YP_002405950.1 218692838 7144221 40649..41152 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase 41152 insB 7144221 insB Escherichia coli UMN026 transposase YP_002405950.1 40649 D 585056 CDS YP_002405951.1 218692839 7144224 41203..42330 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase, IS4 family, IS10 42330 7144224 p1ECUMN_0051 Escherichia coli UMN026 transposase, IS4 family, IS10 YP_002405951.1 41203 D 585056 CDS YP_002405952.1 218692840 7144338 complement(42340..42756) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094472; Product type pr : regulator; transcriptionnal regulator involved in tetracycline resistance 42756 tetD 7144338 tetD Escherichia coli UMN026 transcriptionnal regulator involved in tetracycline resistance YP_002405952.1 42340 R 585056 CDS YP_002405953.1 218692841 7144249 42769..43437 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptionnal regulator involved in tetracycline resistance 43437 tetC 7144249 tetC Escherichia coli UMN026 transcriptionnal regulator involved in tetracycline resistance YP_002405953.1 42769 D 585056 CDS YP_002405954.1 218692842 7144248 complement(43550..44803) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6319234, 6298728, 1848846, 2168416, 8995300; Product type t : transporter; tetracycline efflux transporter 44803 tetA 7144248 tetA Escherichia coli UMN026 tetracycline efflux transporter YP_002405954.1 43550 R 585056 CDS YP_002405955.1 218692843 7144247 44834..45460 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330687, 6311683, 3062183; Product type r : regulator; TetR family transcriptional regulator 45460 tetR 7144247 tetR Escherichia coli UMN026 TetR family transcriptional regulator YP_002405955.1 44834 D 585056 CDS YP_002405956.1 218692844 7144250 complement(45438..46124) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; ArsR family regulatory protein 46124 jemC 7144250 jemC Escherichia coli UMN026 ArsR family regulatory protein YP_002405956.1 45438 R 585056 CDS YP_002405957.1 218692845 7144232 complement(46132..46629) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; regulatory protein in the aminoacid metabolism 46629 7144232 p1ECUMN_0057 Escherichia coli UMN026 regulatory protein in the aminoacid metabolism YP_002405957.1 46132 R 585056 CDS YP_002405958.1 218692846 7144340 complement(46771..47274) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase 47274 insB 7144340 insB Escherichia coli UMN026 transposase YP_002405958.1 46771 R 585056 CDS YP_002405959.1 218692847 7144225 complement(47193..47468) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 47468 insA 7144225 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002405959.1 47193 R 585056 CDS YP_002405960.1 218692848 7144341 complement(47802..48305) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; transposase 48305 insB 7144341 insB Escherichia coli UMN026 transposase YP_002405960.1 47802 R 585056 CDS YP_002405961.1 218692849 7144226 complement(48224..48499) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 48499 insA 7144226 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002405961.1 48224 R 585056 CDS YP_002405962.1 218692850 7144223 complement(48647..48751) 1 NC_011749.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 48751 7144223 p1ECUMN_0064 Escherichia coli UMN026 hypothetical protein YP_002405962.1 48647 R 585056 CDS YP_002405963.1 218692851 7144342 complement(48748..49212) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; Plasmid stable inheritance protein 49212 pemK 7144342 pemK Escherichia coli UMN026 Plasmid stable inheritance protein YP_002405963.1 48748 R 585056 CDS YP_002405964.1 218692852 7144235 complement(49082..49339) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2832364; Product type r : regulator; Plasmid stable inheritance repressor protein 49339 pemI 7144235 pemI Escherichia coli UMN026 Plasmid stable inheritance repressor protein YP_002405964.1 49082 R 585056 CDS YP_002405965.1 218692853 7144234 complement(49400..49621) 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 49621 7144234 p1ECUMN_0067 Escherichia coli UMN026 hypothetical protein YP_002405965.1 49400 R 585056 CDS YP_002405966.1 218692854 7144343 complement(49432..50085) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 50085 7144343 p1ECUMN_0068 Escherichia coli UMN026 hypothetical protein YP_002405966.1 49432 R 585056 CDS YP_002405967.1 218692855 7144344 complement(51023..51892) 1 NC_011749.1 RepA; replication protein 51892 repA 7144344 repA Escherichia coli UMN026 replication protein YP_002405967.1 51023 R 585056 CDS YP_002405968.1 218692856 7144220 complement(52180..52440) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; replication protein 52440 repB 7144220 repB Escherichia coli UMN026 replication protein YP_002405968.1 52180 R 585056 CDS YP_002405969.1 218692857 7144239 complement(52680..53270) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 53270 yihA 7144239 yihA Escherichia coli UMN026 hypothetical protein YP_002405969.1 52680 R 585056 CDS YP_002405970.1 218692858 7144294 complement(53308..53517) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; hemolysin expression-modulating protein hmo 53517 7144294 p1ECUMN_0072 Escherichia coli UMN026 hemolysin expression-modulating protein hmo YP_002405970.1 53308 R 585056 CDS YP_002405971.1 218692859 7144345 complement(53563..54099) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nuclease 54099 7144345 p1ECUMN_0073 Escherichia coli UMN026 nuclease YP_002405971.1 53563 R 585056 CDS YP_002405972.1 218692860 7144346 complement(54269..54481) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 54481 7144346 p1ECUMN_0074 Escherichia coli UMN026 hypothetical protein YP_002405972.1 54269 R 585056 CDS YP_002405973.1 218692861 7144347 complement(54610..55170) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3027040, 2951652; Product type r : regulator; conjugal transfer fertility inhibition protein FinO 55170 finO 7144347 finO Escherichia coli UMN026 conjugal transfer fertility inhibition protein FinO YP_002405973.1 54610 R 585056 CDS YP_002405974.1 218692862 7144213 complement(55273..56133) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; alpha/beta hydrolase 56133 7144213 p1ECUMN_0076 Escherichia coli UMN026 alpha/beta hydrolase YP_002405974.1 55273 R 585056 CDS YP_002405975.1 218692863 7144348 complement(56192..57409) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8444800, 7768788, 1916281, 7915817, 2164585; Product type e : enzyme; F pilin acetylase 57409 traX 7144348 traX Escherichia coli UMN026 F pilin acetylase YP_002405975.1 56192 R 585056 CDS YP_002405976.1 218692864 7144272 complement(56958..62228) 1 NC_011749.1 cleaves origin of transfer and unwinds; oriT relaxase; conjugal transfer protein TraI 62228 traI 7144272 traI Escherichia coli UMN026 conjugal transfer protein TraI YP_002405976.1 56958 R 585056 CDS YP_002405977.1 218692865 7144258 complement(62228..64525) 1 NC_011749.1 type IV secretion system coupling protein; similar to F plasmid TraD; conjugal transfer protein TraD 64525 7144258 p1ECUMN_0079 Escherichia coli UMN026 conjugal transfer protein TraD YP_002405977.1 62228 R 585056 CDS YP_002405978.1 218692866 7144349 complement(64576..65379) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 65379 7144349 p1ECUMN_0080 Escherichia coli UMN026 hypothetical protein YP_002405978.1 64576 R 585056 CDS YP_002405979.1 218692867 7144350 complement(65516..66250) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1359384, 3323526, 7915817, 2087219, 6995306, 9696748, 1730875, 6238226; Product type m : membrane component; conjugal transfer protein TraT 66250 traT 7144350 traT Escherichia coli UMN026 conjugal transfer protein TraT YP_002405979.1 65516 R 585056 CDS YP_002405980.1 218692868 7144268 complement(66296..66781) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3323526; Product type m : membrane component; hypothetical protein 66781 traS 7144268 traS Escherichia coli UMN026 hypothetical protein YP_002405980.1 66296 R 585056 CDS YP_002405981.1 218692869 7144267 complement(66797..69619) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817; Product type m : membrane component; conjugal transfer protein TraG 69619 traG 7144267 traG Escherichia coli UMN026 conjugal transfer protein TraG YP_002405981.1 66797 R 585056 CDS YP_002405982.1 218692870 7144256 complement(69616..70998) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1348105, 7915817, 2656408; Product type s : structure; conjugal transfer protein TraH 70998 traH 7144256 traH Escherichia coli UMN026 conjugal transfer protein TraH YP_002405982.1 69616 R 585056 CDS YP_002405983.1 218692871 7144257 complement(70976..71401) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2656408, 7915817, 2536655; Product type pm : membrane component; conjugal transfer protein TrbF 71401 trbF 7144257 trbF Escherichia coli UMN026 conjugal transfer protein TrbF YP_002405983.1 70976 R 585056 CDS YP_002405984.1 218692872 7144277 complement(71349..71729) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536655, 7915817; Product type pm : membrane component; conjugal transfer protein TrbJ 71729 trbJ 7144277 trbJ Escherichia coli UMN026 conjugal transfer protein TrbJ YP_002405984.1 71349 R 585056 CDS YP_002405985.1 218692873 7144279 complement(71626..72171) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2536655, 7915817; Product type pf : factor; conjugal transfer protein TrbB 72171 trbB 7144279 trbB Escherichia coli UMN026 conjugal transfer protein TrbB YP_002405985.1 71626 R 585056 CDS YP_002405986.1 218692874 7144274 complement(72158..72442) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2536655, 7915817; Product type m : membrane component; conjugal transfer protein TraQ 72442 TraQ 7144274 TraQ Escherichia coli UMN026 conjugal transfer protein TraQ YP_002405986.1 72158 R 585056 CDS YP_002405987.1 218692875 7144265 complement(73194..73967) 1 NC_011749.1 type IV secretion system pilus assembly protein; similar to F plasmid TraF; conjugal transfer protein TraF 73967 traF 7144265 traF Escherichia coli UMN026 conjugal transfer protein TraF YP_002405987.1 73194 R 585056 CDS YP_002405988.1 218692876 7144255 complement(73930..74190) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12533481, 1593622, 7915817; Product type m : membrane component; conjugal transfer protein TrbE 74190 trbE 7144255 trbE Escherichia coli UMN026 conjugal transfer protein TrbE YP_002405988.1 73930 R 585056 CDS YP_002405989.1 218692877 7144276 complement(74214..76064) 1 NC_011749.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell; conjugal transfer mating pair stabilization protein TraN 76064 traN 7144276 traN Escherichia coli UMN026 conjugal transfer mating pair stabilization protein TraN YP_002405989.1 74214 R 585056 CDS YP_002405990.1 218692878 7144263 complement(76061..76711) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2050638, 7915817, 2198250, 1593622; Product type s : structure; conjugal transfer protein TrbC 76711 trbC 7144263 trbC Escherichia coli UMN026 conjugal transfer protein TrbC YP_002405990.1 76061 R 585056 CDS YP_002405991.1 218692879 7144275 complement(76708..77019) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 77019 7144275 p1ECUMN_0094 Escherichia coli UMN026 hypothetical protein YP_002405991.1 76708 R 585056 CDS YP_002405992.1 218692880 7144351 complement(77043..78035) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2198250, 7915817, 2050638, 1355084; Product type s : structure; conjugal transfer protein TraU 78035 traU 7144351 traU Escherichia coli UMN026 conjugal transfer protein TraU YP_002405992.1 77043 R 585056 CDS YP_002405993.1 218692881 7144269 complement(78032..78778) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150, 1355084, 7915817, 2198250; Product type s : structure; conjugal transfer protein TraW 78778 traW 7144269 traW Escherichia coli UMN026 conjugal transfer protein TraW YP_002405993.1 78032 R 585056 CDS YP_002405994.1 218692882 7144271 complement(78661..79047) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292150; Product type m : membrane component; conjugal transfer protein TrbI 79047 trbI 7144271 trbI Escherichia coli UMN026 conjugal transfer protein TrbI YP_002405994.1 78661 R 585056 CDS YP_002405995.1 218692883 7144278 complement(79044..81674) 1 NC_011749.1 similar to VirB4; conjugal transfer protein TraC 81674 traC 7144278 traC Escherichia coli UMN026 conjugal transfer protein TraC YP_002405995.1 79044 R 585056 CDS YP_002405996.1 218692884 7144253 complement(81800..81973) 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 81973 7144253 p1ECUMN_0099 Escherichia coli UMN026 hypothetical protein YP_002405996.1 81800 R 585056 CDS YP_002405997.1 218692885 7144352 complement(82041..82259) 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 82259 7144352 p1ECUMN_0100 Escherichia coli UMN026 hypothetical protein YP_002405997.1 82041 R 585056 CDS YP_002405998.1 218692886 7144353 complement(82339..82854) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 82854 yfiA 7144353 yfiA Escherichia coli UMN026 hypothetical protein YP_002405998.1 82339 R 585056 CDS YP_002405999.1 218692887 7144293 complement(82805..83026) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8021201, 7915817; Product type pf : factor; conjugal transfer protein TraR 83026 traR 7144293 traR Escherichia coli UMN026 conjugal transfer protein TraR YP_002405999.1 82805 R 585056 CDS YP_002406000.1 218692888 7144266 complement(83161..83676) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021201, 7915817; Product type lp : lipoprotein; conjugal transfer protein TraV 83676 traV 7144266 traV Escherichia coli UMN026 conjugal transfer protein TraV YP_002406000.1 83161 R 585056 CDS YP_002406001.1 218692889 7144270 complement(83673..83906) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8021201, 7915817; conjugal transfer protein TrbG 83906 7144270 p1ECUMN_0104 Escherichia coli UMN026 conjugal transfer protein TrbG YP_002406001.1 83673 R 585056 CDS YP_002406002.1 218692890 7144354 complement(83918..84271) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; conjugal transfer protein TrbD 84271 7144354 p1ECUMN_0105 Escherichia coli UMN026 conjugal transfer protein TrbD YP_002406002.1 83918 R 585056 CDS YP_002406003.1 218692891 7144355 complement(84225..84815) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; conjugal transfer protein TraP 84815 traP 7144355 traP Escherichia coli UMN026 conjugal transfer protein TraP YP_002406003.1 84225 R 585056 CDS YP_002406004.1 218692892 7144264 complement(84805..86232) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7915817, 8655498; Product type s : structure; conjugal transfer protein TraB 86232 traB 7144264 traB Escherichia coli UMN026 conjugal transfer protein TraB YP_002406004.1 84805 R 585056 CDS YP_002406005.1 218692893 7144252 complement(86232..86960) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655498; Product type s : structure; conjugal transfer protein TraK 86960 traK 7144252 traK Escherichia coli UMN026 conjugal transfer protein TraK YP_002406005.1 86232 R 585056 CDS YP_002406006.1 218692894 7144260 complement(86947..87513) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817; Product type m : membrane component; conjugal transfer protein TraE 87513 traE 7144260 traE Escherichia coli UMN026 conjugal transfer protein TraE YP_002406006.1 86947 R 585056 CDS YP_002406007.1 218692895 7144254 complement(87535..87846) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2564189, 8655498; Product type m : membrane component; conjugal transfer protein TraL 87846 traL 7144254 traL Escherichia coli UMN026 conjugal transfer protein TraL YP_002406007.1 87535 R 585056 CDS YP_002406008.1 218692896 7144261 complement(87861..88220) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6090426, 7915817, 2999074; Product type s : structure; conjugal transfer pilin subunit TraA 88220 traA 7144261 traA Escherichia coli UMN026 conjugal transfer pilin subunit TraA YP_002406008.1 87861 R 585056 CDS YP_002406009.1 218692897 7144251 complement(88254..88430) 1 NC_011749.1 Evidence 6 : Doubtful CDS; hypothetical protein 88430 7144251 p1ECUMN_0112 Escherichia coli UMN026 hypothetical protein YP_002406009.1 88254 R 585056 CDS YP_002406010.1 218692898 7144301 88290..89306 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; transposase 89306 insH 7144301 insH Escherichia coli UMN026 transposase YP_002406010.1 88290 D 585056 CDS YP_002406011.1 218692899 7144228 complement(89453..89680) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; conjugal transfer protein TraY 89680 traY 7144228 traY Escherichia coli UMN026 conjugal transfer protein TraY YP_002406011.1 89453 R 585056 CDS YP_002406012.1 218692900 7144273 complement(89774..90520) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3012278, 2564189; Product type r : regulator; conjugation transfer regulator 90520 traJ 7144273 traJ Escherichia coli UMN026 conjugation transfer regulator YP_002406012.1 89774 R 585056 CDS YP_002406013.1 218692901 7144214 complement(90654..91037) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995191; Product type f : factor; conjugal transfer protein TraM 91037 traM 7144214 traM Escherichia coli UMN026 conjugal transfer protein TraM YP_002406013.1 90654 R 585056 CDS YP_002406014.1 218692902 7144262 91368..91970 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; lytic transglycosylase 91970 yubQ 7144262 yubQ Escherichia coli UMN026 lytic transglycosylase YP_002406014.1 91368 D 585056 CDS YP_002406015.1 218692903 7144299 complement(92266..93171) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 93171 yubP 7144299 yubP Escherichia coli UMN026 hypothetical protein YP_002406015.1 92266 R 585056 CDS YP_002406016.1 218692904 7144298 complement(93206..93493) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 93493 yubO 7144298 yubO Escherichia coli UMN026 hypothetical protein YP_002406016.1 93206 R 585056 CDS YP_002406017.1 218692905 7144297 complement(94413..94625) 1 NC_011749.1 Mok; similar to F leading maintenance protein C; modulator of post-segregation killing protein 94625 flmC 7144297 flmC Escherichia coli UMN026 modulator of post-segregation killing protein YP_002406017.1 94413 R 585056 CDS YP_002406018.1 218692906 7144215 complement(94843..95562) 1 NC_011749.1 PsiA; plasmid SOS inhibition protein A 95562 psiA 7144215 psiA Escherichia coli UMN026 plasmid SOS inhibition protein A YP_002406018.1 94843 R 585056 CDS YP_002406019.1 218692907 7144236 complement(95559..95996) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9987116, 10537187; Product type f : factor; plasmid SOS inhibition protein B 95996 psiB 7144236 psiB Escherichia coli UMN026 plasmid SOS inhibition protein B YP_002406019.1 95559 R 585056 CDS YP_002406020.1 218692908 7144237 complement(96048..98096) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; ParB-like nuclease 98096 ycjA 7144237 ycjA Escherichia coli UMN026 ParB-like nuclease YP_002406020.1 96048 R 585056 CDS YP_002406021.1 218692909 7144286 complement(98065..98325) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 98325 yubL 7144286 yubL Escherichia coli UMN026 hypothetical protein YP_002406021.1 98065 R 585056 CDS YP_002406022.1 218692910 7144296 complement(98355..98921) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; Product type cp : cell process; single-stranded DNA-binding protein 98921 ssb 7144296 ssb Escherichia coli UMN026 single-stranded DNA-binding protein YP_002406022.1 98355 R 585056 CDS YP_002406023.1 218692911 7144246 complement(99708..100271) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; adenine-specific DNA methylase 100271 ydcA 7144246 ydcA Escherichia coli UMN026 adenine-specific DNA methylase YP_002406023.1 99708 R 585056 CDS YP_002406024.1 218692912 7144288 complement(100318..101679) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 101679 ydbA 7144288 ydbA Escherichia coli UMN026 hypothetical protein YP_002406024.1 100318 R 585056 CDS YP_002406025.1 218692913 7144287 complement(102924..103115) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 103115 7144287 p1ECUMN_0130 Escherichia coli UMN026 hypothetical protein YP_002406025.1 102924 R 585056 CDS YP_002406026.1 218692914 7144200 complement(103112..103486) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 103486 7144200 p1ECUMN_0131 Escherichia coli UMN026 hypothetical protein YP_002406026.1 103112 R 585056 CDS YP_002406027.1 218692915 7144201 complement(103583..104008) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antirestriction protein 104008 7144201 p1ECUMN_0132 Escherichia coli UMN026 antirestriction protein YP_002406027.1 103583 R 585056 CDS YP_002406028.1 218692916 7144202 complement(104424..105194) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 105194 ycfA 7144202 ycfA Escherichia coli UMN026 hypothetical protein YP_002406028.1 104424 R 585056 CDS YP_002406029.1 218692917 7144285 complement(105239..105673) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 105673 yfcB 7144285 yfcB Escherichia coli UMN026 hypothetical protein YP_002406029.1 105239 R 585056 CDS YP_002406030.1 218692918 7144291 complement(105687..105908) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 105908 yfeB 7144291 yfeB Escherichia coli UMN026 hypothetical protein YP_002406030.1 105687 R 585056 CDS YP_002406031.1 218692919 7144292 complement(105909..106592) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylase 106592 7144292 p1ECUMN_0137 Escherichia coli UMN026 methylase YP_002406031.1 105909 R 585056 CDS YP_002406032.1 218692920 7144203 complement(106976..107947) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 107947 yccB 7144203 yccB Escherichia coli UMN026 hypothetical protein YP_002406032.1 106976 R 585056 CDS YP_002406033.1 218692921 7144284 complement(107916..108185) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 108185 yuaZ 7144284 yuaZ Escherichia coli UMN026 hypothetical protein YP_002406033.1 107916 R 585056 CDS YP_002406034.1 218692922 7144295 complement(108297..109517) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase 109517 7144295 p1ECUMN_0141 Escherichia coli UMN026 transposase YP_002406034.1 108297 R 585056 CDS YP_002406035.1 218692923 7144204 complement(109536..110054) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 110054 7144204 p1ECUMN_0142 Escherichia coli UMN026 hypothetical protein YP_002406035.1 109536 R 585056 CDS YP_002406036.1 218692924 7144205 110189..110437 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; UV protection and mutation protein 110437 impC 7144205 impC Escherichia coli UMN026 UV protection and mutation protein YP_002406036.1 110189 D 585056 CDS YP_002406037.1 218692925 7144219 110434..110871 1 NC_011749.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2129552; Product type f : factor; UV protection and mutation protein 110871 impA 7144219 impA Escherichia coli UMN026 UV protection and mutation protein YP_002406037.1 110434 D 585056 CDS YP_002406038.1 218692926 7144280 111994..113166 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF1, IS21 113166 istA 7144280 istA Escherichia coli UMN026 transposase ORF1, IS21 YP_002406038.1 111994 D 585056 CDS YP_002406039.1 218692927 7144230 113163..113963 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase ORF2, IS21, ATP-binding protein 113963 istB 7144230 istB Escherichia coli UMN026 transposase ORF2, IS21, ATP-binding protein YP_002406039.1 113163 D 585056 CDS YP_002406040.1 218692928 7144281 complement(114281..114709) 1 NC_011749.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; stable plasmid inheritance protein 114709 7144281 p1ECUMN_0150 Escherichia coli UMN026 stable plasmid inheritance protein YP_002406040.1 114281 R 585056 CDS YP_002406041.1 218692929 7144206 complement(114678..115649) 1 NC_011749.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3172224, 3023637, 12486014; Product type f : factor; Plasmid segregation protein 115649 parM 7144206 parM Escherichia coli UMN026 Plasmid segregation protein YP_002406041.1 114678 R 585056 CDS YP_002406042.1 218692930 7144233 115878..116522 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 116522 7144233 p1ECUMN_0152 Escherichia coli UMN026 hypothetical protein YP_002406042.1 115878 D 585056 CDS YP_002406043.1 218692931 7144207 116516..116791 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 116791 7144207 p1ECUMN_0153 Escherichia coli UMN026 hypothetical protein YP_002406043.1 116516 D 585056 CDS YP_002406044.1 218692932 7144208 complement(116929..117738) 1 NC_011749.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3027661, 3007930, 6327993; Product type e : enzyme; resolvase 117738 resD 7144208 resD Escherichia coli UMN026 resolvase YP_002406044.1 116929 R 585056 CDS YP_002406045.1 218692933 7144241 complement(117739..118071) 1 NC_011749.1 controlled cell death protein; post-segregation toxin; toxin addiction system; plasmid maintenance protein CcdB 118071 ccdB 7144241 ccdB Escherichia coli UMN026 plasmid maintenance protein CcdB YP_002406045.1 117739 R 585056 CDS YP_002406046.1 218692934 7144210 complement(118046..118324) 1 NC_011749.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; plasmid maintenance protein CcdA 118324 ccdA 7144210 ccdA Escherichia coli UMN026 plasmid maintenance protein CcdA YP_002406046.1 118046 R 585056 CDS YP_002406047.1 218692935 7144282 120586..121227 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 121227 ydiA 7144282 ydiA Escherichia coli UMN026 hypothetical protein YP_002406047.1 120586 D 585056 CDS YP_002406048.1 218692936 7144290 complement(121095..121415) 1 NC_011749.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 121415 7144290 p1ECUMN_0160 Escherichia coli UMN026 hypothetical protein YP_002406048.1 121095 R 585056 CDS YP_002410781.1 218703262 7159698 149..214 1 NC_011751.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 214 thrL 7159698 thrL Escherichia coli UMN026 thr operon leader peptide YP_002410781.1 149 D 585056 CDS YP_002410782.1 218703263 7158067 295..2757 1 NC_011751.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2757 thrA 7158067 thrA Escherichia coli UMN026 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002410782.1 295 D 585056 CDS YP_002410783.1 218703264 7158064 2759..3691 1 NC_011751.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3691 thrB 7158064 thrB Escherichia coli UMN026 homoserine kinase YP_002410783.1 2759 D 585056 CDS YP_002410784.1 218703265 7158065 3692..4978 1 NC_011751.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 4978 thrC 7158065 thrC Escherichia coli UMN026 threonine synthase YP_002410784.1 3692 D 585056 CDS YP_002410785.1 218703266 7158066 5192..5488 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5488 yaaX 7158066 yaaX Escherichia coli UMN026 hypothetical protein YP_002410785.1 5192 D 585056 CDS YP_002410786.1 218703267 7158263 complement(5641..6417) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 6417 yaaA 7158263 yaaA Escherichia coli UMN026 hypothetical protein YP_002410786.1 5641 R 585056 CDS YP_002410787.1 218703268 7158258 complement(6487..7917) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino acid sodium/proton transporter 7917 yaaJ 7158258 yaaJ Escherichia coli UMN026 putative amino acid sodium/proton transporter YP_002410787.1 6487 R 585056 CDS YP_002410788.1 218703269 7158261 8196..9149 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme; transaldolase B 9149 talB 7158261 talB Escherichia coli UMN026 transaldolase B YP_002410788.1 8196 D 585056 CDS YP_002410789.1 218703270 7158020 9264..9851 1 NC_011751.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9851 mogA 7158020 mogA Escherichia coli UMN026 molybdenum cofactor biosynthesis protein MogA YP_002410789.1 9264 D 585056 CDS YP_002410790.1 218703271 7157160 complement(9886..10452) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 10452 yaaH 7157160 yaaH Escherichia coli UMN026 hypothetical protein YP_002410790.1 9886 R 585056 CDS YP_002410791.1 218703272 7158259 complement(10601..11314) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8478327; Product type r : regulator; hypothetical protein 11314 htpY 7158259 htpY Escherichia coli UMN026 hypothetical protein YP_002410791.1 10601 R 585056 CDS YP_002410792.1 218703273 7156728 complement(11340..11744) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 11744 yaaI 7156728 yaaI Escherichia coli UMN026 hypothetical protein YP_002410792.1 11340 R 585056 CDS YP_002410793.1 218703274 7158260 12120..14036 1 NC_011751.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 14036 dnaK 7158260 dnaK Escherichia coli UMN026 molecular chaperone DnaK YP_002410793.1 12120 D 585056 CDS YP_002410794.1 218703275 7158099 14125..15255 1 NC_011751.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 15255 dnaJ 7158099 dnaJ Escherichia coli UMN026 chaperone protein DnaJ YP_002410794.1 14125 D 585056 CDS YP_002410795.1 218703276 7157951 16097..17263 1 NC_011751.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17263 nhaA 7157951 nhaA Escherichia coli UMN026 pH-dependent sodium/proton antiporter YP_002410795.1 16097 D 585056 CDS YP_002410796.1 218703277 7157271 17323..18228 1 NC_011751.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18228 nhaR 7157271 nhaR Escherichia coli UMN026 transcriptional activator NhaR YP_002410796.1 17323 D 585056 CDS YP_002410797.1 218703278 7157273 complement(18266..19225) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 19225 7157273 ECUMN_0018 Escherichia coli UMN026 hypothetical protein YP_002410797.1 18266 R 585056 CDS YP_002410798.1 218703279 7154603 complement(19238..21688) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative fimbrial biogenesis outer membrane usher protein 21688 7154603 ECUMN_0019 Escherichia coli UMN026 putative fimbrial biogenesis outer membrane usher protein YP_002410798.1 19238 R 585056 CDS YP_002410799.1 218703280 7154604 complement(21701..22384) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative membrane-associated pilin chaperone 22384 7154604 ECUMN_0020 Escherichia coli UMN026 putative membrane-associated pilin chaperone YP_002410799.1 21701 R 585056 CDS YP_002410800.1 218703281 7154605 complement(22434..22967) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like protein 22967 7154605 ECUMN_0021 Escherichia coli UMN026 putative fimbrial-like protein YP_002410800.1 22434 R 585056 CDS YP_002410801.1 218703282 7154606 complement(23268..24689) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 24689 7154606 ECUMN_0022 Escherichia coli UMN026 hypothetical protein YP_002410801.1 23268 R 585056 CDS YP_002410802.1 218703283 7154607 complement(25173..25436) 1 NC_011751.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 25436 rpsT 7154607 rpsT Escherichia coli UMN026 30S ribosomal protein S20 YP_002410802.1 25173 R 585056 CDS YP_002410803.1 218703284 7157786 25539..25757 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 25757 yaaY 7157786 yaaY Escherichia coli UMN026 hypothetical protein YP_002410803.1 25539 D 585056 CDS YP_002410804.1 218703285 7158264 25765..26706 1 NC_011751.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 26706 ribF 7158264 ribF Escherichia coli UMN026 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002410804.1 25765 D 585056 CDS YP_002410805.1 218703286 7157687 26749..29565 1 NC_011751.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 29565 ileS 7157687 ileS Escherichia coli UMN026 isoleucyl-tRNA synthetase YP_002410805.1 26749 D 585056 CDS YP_002410806.1 218703287 7156796 29565..30059 1 NC_011751.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 30059 lspA 7156796 lspA Escherichia coli UMN026 lipoprotein signal peptidase YP_002410806.1 29565 D 585056 CDS YP_002410807.1 218703288 7157019 30146..30595 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase 30595 fkpB 7157019 fkpB Escherichia coli UMN026 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002410807.1 30146 D 585056 CDS YP_002410808.1 218703289 7156374 30597..31547 1 NC_011751.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 31547 ispH 7156374 ispH Escherichia coli UMN026 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002410808.1 30597 D 585056 CDS YP_002410809.1 218703290 7156868 31613..32527 1 NC_011751.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 32527 rihC 7156868 rihC Escherichia coli UMN026 ribonucleoside hydrolase RihC YP_002410809.1 31613 D 585056 CDS YP_002410810.1 218703291 7157690 32694..33515 1 NC_011751.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 33515 dapB 7157690 dapB Escherichia coli UMN026 dihydrodipicolinate reductase YP_002410810.1 32694 D 585056 CDS YP_002410811.1 218703292 7156108 33971..35119 1 NC_011751.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 35119 carA 7156108 carA Escherichia coli UMN026 carbamoyl phosphate synthase small subunit YP_002410811.1 33971 D 585056 CDS YP_002410812.1 218703293 7155918 35137..38355 1 NC_011751.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 38355 carB 7155918 carB Escherichia coli UMN026 carbamoyl phosphate synthase large subunit YP_002410812.1 35137 D 585056 CDS YP_002410813.1 218703294 7155919 complement(38363..38581) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7815937, 6308632; hypothetical protein 38581 7155919 ECUMN_0035 Escherichia coli UMN026 hypothetical protein YP_002410813.1 38363 R 585056 CDS YP_002410814.1 218703295 7154608 38616..39011 1 NC_011751.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 39011 caiF 7154608 caiF Escherichia coli UMN026 DNA-binding transcriptional activator CaiF YP_002410814.1 38616 D 585056 CDS YP_002410815.1 218703296 7155915 complement(39217..39807) 1 NC_011751.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 39807 caiE 7155915 caiE Escherichia coli UMN026 carnitine operon protein CaiE YP_002410815.1 39217 R 585056 CDS YP_002410816.2 229598881 7155914 complement(39813..40598) 1 NC_011751.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 40598 caiD 7155914 caiD Escherichia coli UMN026 carnitinyl-CoA dehydratase YP_002410816.2 39813 R 585056 CDS YP_002410817.1 218703298 7155913 complement(40707..42275) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme; putative crotonobetaine/carnitine-CoA ligase 42275 caiC 7155913 caiC Escherichia coli UMN026 putative crotonobetaine/carnitine-CoA ligase YP_002410817.1 40707 R 585056 CDS YP_002410818.1 218703299 7155912 complement(42334..43551) 1 NC_011751.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 43551 caiB 7155912 caiB Escherichia coli UMN026 crotonobetainyl-CoA:carnitine CoA-transferase YP_002410818.1 42334 R 585056 CDS YP_002410819.1 218703300 7155911 complement(43680..44822) 1 NC_011751.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 44822 caiA 7155911 caiA Escherichia coli UMN026 crotonobetainyl-CoA dehydrogenase YP_002410819.1 43680 R 585056 CDS YP_002410820.1 218703301 7155910 complement(44853..46367) 1 NC_011751.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 46367 caiT 7155910 caiT Escherichia coli UMN026 L-carnitine/gamma-butyrobetaine antiporter YP_002410820.1 44853 R 585056 CDS YP_002410821.1 218703302 7155916 46840..47610 1 NC_011751.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 47610 fixA 7155916 fixA Escherichia coli UMN026 putative electron transfer flavoprotein FixA YP_002410821.1 46840 D 585056 CDS YP_002410822.1 218703303 7156368 47625..48566 1 NC_011751.1 involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 48566 fixB 7156368 fixB Escherichia coli UMN026 putative electron transfer flavoprotein FixB YP_002410822.1 47625 D 585056 CDS YP_002410823.1 218703304 7156369 48617..49903 1 NC_011751.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 49903 fixC 7156369 fixC Escherichia coli UMN026 putative oxidoreductase FixC YP_002410823.1 48617 D 585056 CDS YP_002410824.1 218703305 7156370 49900..50187 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : putative carrier; putative 4Fe-4S ferredoxin 50187 fixX 7156370 fixX Escherichia coli UMN026 putative 4Fe-4S ferredoxin YP_002410824.1 49900 D 585056 CDS YP_002410825.1 218703306 7156371 50246..51577 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 51577 yaaU 7156371 yaaU Escherichia coli UMN026 putative transporter YP_002410825.1 50246 D 585056 CDS YP_002410826.1 218703307 7158262 51685..52215 1 NC_011751.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 52215 kefF 7158262 kefF Escherichia coli UMN026 glutathione-regulated potassium-efflux system ancillary protein KefF YP_002410826.1 51685 D 585056 CDS YP_002410827.1 218703308 7156905 52208..54070 1 NC_011751.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 54070 kefC 7156905 kefC Escherichia coli UMN026 glutathione-regulated potassium-efflux system protein KefC YP_002410827.1 52208 D 585056 CDS YP_002410828.1 218703309 7156904 54262..54741 1 NC_011751.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 54741 folA 7156904 folA Escherichia coli UMN026 dihydrofolate reductase YP_002410828.1 54262 D 585056 CDS YP_002410829.1 218703310 7156423 complement(54819..55661) 1 NC_011751.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 55661 apaH 7156423 apaH Escherichia coli UMN026 diadenosine tetraphosphatase YP_002410829.1 54819 R 585056 CDS YP_002410830.1 218703311 7155749 complement(55668..56045) 1 NC_011751.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 56045 apaG 7155749 apaG Escherichia coli UMN026 ApaG protein YP_002410830.1 55668 R 585056 CDS YP_002410831.1 218703312 7155748 complement(56048..56869) 1 NC_011751.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 56869 ksgA 7155748 ksgA Escherichia coli UMN026 dimethyladenosine transferase YP_002410831.1 56048 R 585056 CDS YP_002410832.1 218703313 7156918 complement(56866..57855) 1 NC_011751.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 57855 pdxA 7156918 pdxA Escherichia coli UMN026 4-hydroxythreonine-4-phosphate dehydrogenase YP_002410832.1 56866 R 585056 CDS YP_002410833.1 218703314 7157404 complement(57855..59141) 1 NC_011751.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 59141 surA 7157404 surA Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase SurA YP_002410833.1 57855 R 585056 CDS YP_002410834.1 218703315 7158013 complement(59194..61548) 1 NC_011751.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 61548 imp 7158013 imp Escherichia coli UMN026 organic solvent tolerance protein YP_002410834.1 59194 R 585056 CDS YP_002410835.1 218703316 7156809 61803..62618 1 NC_011751.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 62618 djlA 7156809 djlA Escherichia coli UMN026 Dna-J like membrane chaperone protein YP_002410835.1 61803 D 585056 CDS YP_002410836.1 218703317 7156172 62913..63644 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 63644 7156172 ECUMN_0058 Escherichia coli UMN026 hypothetical protein YP_002410836.1 62913 D 585056 CDS YP_002410837.1 218703318 7154609 complement(64052..64711) 1 NC_011751.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 64711 rluA 7154609 rluA Escherichia coli UMN026 23S rRNA/tRNA pseudouridine synthase A YP_002410837.1 64052 R 585056 CDS YP_002410838.1 218703319 7157699 complement(64723..67629) 1 NC_011751.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 67629 hepA 7157699 hepA Escherichia coli UMN026 ATP-dependent helicase HepA YP_002410838.1 64723 R 585056 CDS YP_002410839.1 218703320 7156662 complement(67793..70144) 1 NC_011751.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 70144 polB 7156662 polB Escherichia coli UMN026 DNA polymerase II YP_002410839.1 67793 R 585056 CDS YP_002410840.1 218703321 7157486 complement(70219..70914) 1 NC_011751.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 70914 araD 7157486 araD Escherichia coli UMN026 L-ribulose-5-phosphate 4-epimerase YP_002410840.1 70219 R 585056 CDS YP_002410841.1 218703322 7155760 complement(71199..72701) 1 NC_011751.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 72701 araA 7155760 araA Escherichia coli UMN026 L-arabinose isomerase YP_002410841.1 71199 R 585056 CDS YP_002410842.1 218703323 7155757 complement(72712..74412) 1 NC_011751.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 74412 araB 7155757 araB Escherichia coli UMN026 ribulokinase YP_002410842.1 72712 R 585056 CDS YP_002410843.1 218703324 7155758 74751..75629 1 NC_011751.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 75629 araC 7155758 araC Escherichia coli UMN026 DNA-binding transcriptional regulator AraC YP_002410843.1 74751 D 585056 CDS YP_002410844.1 218703325 7155759 75715..76479 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 76479 yabI 7155759 yabI Escherichia coli UMN026 hypothetical protein YP_002410844.1 75715 D 585056 CDS YP_002410845.1 218703326 7158265 complement(76593..77291) 1 NC_011751.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 77291 thiQ 7158265 thiQ Escherichia coli UMN026 thiamine transporter ATP-binding subunit YP_002410845.1 76593 R 585056 CDS YP_002410846.1 218703327 7158062 complement(77275..78885) 1 NC_011751.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 78885 thiP 7158062 thiP Escherichia coli UMN026 thiamine transporter membrane protein YP_002410846.1 77275 R 585056 CDS YP_002410847.1 218703328 7158061 complement(78861..79844) 1 NC_011751.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 79844 tbpA 7158061 tbpA Escherichia coli UMN026 thiamine transporter substrate binding subunit YP_002410847.1 78861 R 585056 CDS YP_002410848.1 218703329 7158034 complement(79888..80112) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 80112 7158034 ECUMN_0070 Escherichia coli UMN026 hypothetical protein YP_002410848.1 79888 R 585056 CDS YP_002410849.1 218703330 7154610 80215..81051 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 81051 7154610 ECUMN_0071 Escherichia coli UMN026 hypothetical protein YP_002410849.1 80215 D 585056 CDS YP_002410850.1 218703331 7154611 complement(81548..83227) 1 NC_011751.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 83227 sgrR 7154611 sgrR Escherichia coli UMN026 transcriptional regulator SgrR YP_002410850.1 81548 R 585056 CDS YP_002410851.1 218703332 7157922 complement(83534..84139) 1 NC_011751.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 84139 leuD 7157922 leuD Escherichia coli UMN026 isopropylmalate isomerase small subunit YP_002410851.1 83534 R 585056 CDS YP_002410852.1 218703333 7156945 complement(84150..85550) 1 NC_011751.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 85550 leuC 7156945 leuC Escherichia coli UMN026 isopropylmalate isomerase large subunit YP_002410852.1 84150 R 585056 CDS YP_002410853.1 218703334 7156944 complement(85553..86644) 1 NC_011751.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 86644 leuB 7156944 leuB Escherichia coli UMN026 3-isopropylmalate dehydrogenase YP_002410853.1 85553 R 585056 CDS YP_002410854.1 218703335 7156943 complement(86644..88215) 1 NC_011751.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 88215 leuA 7156943 leuA Escherichia coli UMN026 2-isopropylmalate synthase YP_002410854.1 86644 R 585056 CDS YP_002410855.1 218703336 7156942 complement(88308..88394) 1 NC_011751.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 88394 leuL 7156942 leuL Escherichia coli UMN026 leu operon leader peptide YP_002410855.1 88308 R 585056 CDS YP_002410856.1 218703337 7156946 89053..89997 1 NC_011751.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 89997 leuO 7156946 leuO Escherichia coli UMN026 leucine transcriptional activator YP_002410856.1 89053 D 585056 CDS YP_002410857.1 218703338 7156947 90315..92039 1 NC_011751.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 92039 ilvI 7156947 ilvI Escherichia coli UMN026 acetolactate synthase 3 catalytic subunit YP_002410857.1 90315 D 585056 CDS YP_002410858.1 218703339 7156804 92042..92533 1 NC_011751.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 92533 ilvH 7156804 ilvH Escherichia coli UMN026 acetolactate synthase 3 regulatory subunit YP_002410858.1 92042 D 585056 CDS YP_002410859.1 218703340 7156803 92713..93717 1 NC_011751.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 93717 fruR 7156803 fruR Escherichia coli UMN026 DNA-binding transcriptional regulator FruR YP_002410859.1 92713 D 585056 CDS YP_002410860.1 218703341 7156448 94319..94777 1 NC_011751.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 94777 mraZ 7156448 mraZ Escherichia coli UMN026 cell division protein MraZ YP_002410860.1 94319 D 585056 CDS YP_002410861.1 218703342 7157174 94779..95720 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme; S-adenosyl-methyltransferase MraW 95720 mraW 7157174 mraW Escherichia coli UMN026 S-adenosyl-methyltransferase MraW YP_002410861.1 94779 D 585056 CDS YP_002410862.1 218703343 7157172 95717..96082 1 NC_011751.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 96082 ftsL 7157172 ftsL Escherichia coli UMN026 cell division protein FtsL YP_002410862.1 95717 D 585056 CDS YP_002410863.1 218703344 7156462 96098..97864 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme; septal peptidoglycan synthesis transpeptidase 97864 ftsI 7156462 ftsI Escherichia coli UMN026 septal peptidoglycan synthesis transpeptidase YP_002410863.1 96098 D 585056 CDS YP_002410864.1 218703345 7156460 97851..99338 1 NC_011751.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 99338 murE 7156460 murE Escherichia coli UMN026 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002410864.1 97851 D 585056 CDS YP_002410865.1 218703346 7157205 99335..100693 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 100693 murF 7157205 murF Escherichia coli UMN026 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002410865.1 99335 D 585056 CDS YP_002410866.1 218703347 7157206 100687..101769 1 NC_011751.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 101769 mraY 7157206 mraY Escherichia coli UMN026 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002410866.1 100687 D 585056 CDS YP_002410867.1 218703348 7157173 101772..103088 1 NC_011751.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 103088 murD 7157173 murD Escherichia coli UMN026 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002410867.1 101772 D 585056 CDS YP_002410868.1 218703349 7157204 103088..104332 1 NC_011751.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 104332 ftsW 7157204 ftsW Escherichia coli UMN026 cell division protein FtsW YP_002410868.1 103088 D 585056 CDS YP_002410869.1 218703350 7156465 104329..105396 1 NC_011751.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 105396 murG 7156465 murG Escherichia coli UMN026 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_002410869.1 104329 D 585056 CDS YP_002410870.1 218703351 7157207 105450..106925 1 NC_011751.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 106925 murC 7157207 murC Escherichia coli UMN026 UDP-N-acetylmuramate--L-alanine ligase YP_002410870.1 105450 D 585056 CDS YP_002410871.1 218703352 7157203 106918..107838 1 NC_011751.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 107838 ddl 7157203 ddl Escherichia coli UMN026 D-alanine--D-alanine ligase YP_002410871.1 106918 D 585056 CDS YP_002410872.1 218703353 7156126 107840..108670 1 NC_011751.1 involved in septum formation; cell division protein FtsQ 108670 ftsQ 7156126 ftsQ Escherichia coli UMN026 cell division protein FtsQ YP_002410872.1 107840 D 585056 CDS YP_002410873.1 218703354 7156464 108667..109929 1 NC_011751.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 109929 ftsA 7156464 ftsA Escherichia coli UMN026 cell division protein FtsA YP_002410873.1 108667 D 585056 CDS YP_002410874.1 218703355 7156456 109990..111141 1 NC_011751.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 111141 ftsZ 7156456 ftsZ Escherichia coli UMN026 cell division protein FtsZ YP_002410874.1 109990 D 585056 CDS YP_002410875.1 218703356 7156468 111242..112159 1 NC_011751.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 112159 lpxC 7156468 lpxC Escherichia coli UMN026 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002410875.1 111242 D 585056 CDS YP_002410876.1 218703357 7157011 112390..112902 1 NC_011751.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 112902 secM 7157011 secM Escherichia coli UMN026 SecA regulator SecM YP_002410876.1 112390 D 585056 CDS YP_002410877.1 218703358 7157891 112964..115669 1 NC_011751.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 115669 secA 7157891 secA Escherichia coli UMN026 preprotein translocase subunit SecA YP_002410877.1 112964 D 585056 CDS YP_002410878.1 218703359 7157885 115729..116127 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme; nucleoside triphosphate pyrophosphohydrolase 116127 mutT 7157885 mutT Escherichia coli UMN026 nucleoside triphosphate pyrophosphohydrolase YP_002410878.1 115729 D 585056 CDS YP_002410879.1 218703360 7157215 complement(116422..117165) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 117165 yacF 7157215 yacF Escherichia coli UMN026 hypothetical protein YP_002410879.1 116422 R 585056 CDS YP_002410880.1 218703361 7158267 complement(117165..117785) 1 NC_011751.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 117785 coaE 7158267 coaE Escherichia coli UMN026 dephospho-CoA kinase YP_002410880.1 117165 R 585056 CDS YP_002410881.1 218703362 7155990 118010..119053 1 NC_011751.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 119053 guaC 7155990 guaC Escherichia coli UMN026 guanosine 5'-monophosphate oxidoreductase YP_002410881.1 118010 D 585056 CDS YP_002410882.1 218703363 7156624 complement(119088..120290) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96099298, 2904262, 7959070; Product type s : structure; type IV pilin biogenesis protein 120290 hofC 7156624 hofC Escherichia coli UMN026 type IV pilin biogenesis protein YP_002410882.1 119088 R 585056 CDS YP_002410883.1 218703364 7156692 complement(120280..121665) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96099298, 7959070; Product type pt : putative transporter; hypothetical protein 121665 hofB 7156692 hofB Escherichia coli UMN026 hypothetical protein YP_002410883.1 120280 R 585056 CDS YP_002410884.1 218703365 7156691 complement(121675..122115) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : putative structure; putative major pilin subunit 122115 ppdD 7156691 ppdD Escherichia coli UMN026 putative major pilin subunit YP_002410884.1 121675 R 585056 CDS YP_002410885.1 218703366 7157502 complement(122318..123211) 1 NC_011751.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 123211 nadC 7157502 nadC Escherichia coli UMN026 quinolinate phosphoribosyltransferase YP_002410885.1 122318 R 585056 CDS YP_002410886.1 218703367 7157223 123299..123850 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme; N-acetyl-anhydromuranmyl-L-alanine amidase 123850 ampD 7157223 ampD Escherichia coli UMN026 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002410886.1 123299 D 585056 CDS YP_002410887.1 218703368 7155738 123847..124701 1 NC_011751.1 involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 124701 ampE 7155738 ampE Escherichia coli UMN026 regulatory protein AmpE YP_002410887.1 123847 D 585056 CDS YP_002410888.1 218703369 7155739 complement(124744..126117) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter; aromatic amino acid transporter 126117 aroP 7155739 aroP Escherichia coli UMN026 aromatic amino acid transporter YP_002410888.1 124744 R 585056 CDS YP_002410889.1 218703370 7155794 126658..127422 1 NC_011751.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 127422 pdhR 7155794 pdhR Escherichia coli UMN026 transcriptional regulator PdhR YP_002410889.1 126658 D 585056 CDS YP_002410890.1 218703371 7158097 127583..130246 1 NC_011751.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 130246 aceE 7158097 aceE Escherichia coli UMN026 pyruvate dehydrogenase subunit E1 YP_002410890.1 127583 D 585056 CDS YP_002410891.1 218703372 7155677 130261..132153 1 NC_011751.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 132153 aceF 7155677 aceF Escherichia coli UMN026 dihydrolipoamide acetyltransferase YP_002410891.1 130261 D 585056 CDS YP_002410892.1 218703373 7155678 132361..133785 1 NC_011751.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 133785 lpd 7155678 lpd Escherichia coli UMN026 dihydrolipoamide dehydrogenase YP_002410892.1 132361 D 585056 CDS YP_002410893.1 218703374 7157001 complement(133856..135709) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 135709 yacH 7157001 yacH Escherichia coli UMN026 hypothetical protein YP_002410893.1 133856 R 585056 CDS YP_002410894.1 218703375 7158268 136064..138661 1 NC_011751.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 138661 acnB 7158268 acnB Escherichia coli UMN026 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002410894.1 136064 D 585056 CDS YP_002410895.1 218703376 7155682 138858..139220 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469; hypothetical protein 139220 yacL 7155682 yacL Escherichia coli UMN026 hypothetical protein YP_002410895.1 138858 D 585056 CDS YP_002410896.1 218703377 7158269 complement(139258..140052) 1 NC_011751.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 140052 speD 7158269 speD Escherichia coli UMN026 S-adenosylmethionine decarboxylase YP_002410896.1 139258 R 585056 CDS YP_002410897.1 218703378 7157960 complement(140068..140934) 1 NC_011751.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 140934 speE 7157960 speE Escherichia coli UMN026 spermidine synthase YP_002410897.1 140068 R 585056 CDS YP_002410898.1 218703379 7157961 complement(141040..141558) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401; hypothetical protein 141558 yacC 7157961 yacC Escherichia coli UMN026 hypothetical protein YP_002410898.1 141040 R 585056 CDS YP_002410899.1 218703380 7158266 141553..143103 1 NC_011751.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 143103 cueO 7158266 cueO Escherichia coli UMN026 multicopper oxidase YP_002410899.1 141553 D 585056 CDS YP_002410900.1 218703381 7156048 complement(143150..145540) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme; glucose dehydrogenase 145540 gcd 7156048 gcd Escherichia coli UMN026 glucose dehydrogenase YP_002410900.1 143150 R 585056 CDS YP_002410901.1 218703382 7156517 145746..146282 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme; hypoxanthine phosphoribosyltransferase 146282 hpt 7156517 hpt Escherichia coli UMN026 hypoxanthine phosphoribosyltransferase YP_002410901.1 145746 D 585056 CDS YP_002410902.1 218703383 7156711 complement(146323..146985) 1 NC_011751.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 146985 can 7156711 can Escherichia coli UMN026 carbonic anhydrase YP_002410902.1 146323 R 585056 CDS YP_002410903.1 218703384 7155917 147094..148020 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 148020 yadG 7155917 yadG Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002410903.1 147094 D 585056 CDS YP_002410904.1 218703385 7158273 148017..148787 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : putative transporter; putative ABC transporter membrane protein 148787 yadH 7158273 yadH Escherichia coli UMN026 putative ABC transporter membrane protein YP_002410904.1 148017 D 585056 CDS YP_002410905.1 218703386 7158274 148892..149332 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS Enzyme IIA 149332 yadI 7158274 yadI Escherichia coli UMN026 putative PTS Enzyme IIA YP_002410905.1 148892 D 585056 CDS YP_002410906.1 218703387 7158275 149396..150625 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported polysaccharide deacetylase 150625 yadE 7158275 yadE Escherichia coli UMN026 putative exported polysaccharide deacetylase YP_002410906.1 149396 D 585056 CDS YP_002410907.1 218703388 7158272 complement(150629..151009) 1 NC_011751.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 151009 panD 7158272 panD Escherichia coli UMN026 aspartate alpha-decarboxylase YP_002410907.1 150629 R 585056 CDS YP_002410908.1 218703389 7157379 151283..152227 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : putative enzyme; putative transposase 152227 yadD 7157379 yadD Escherichia coli UMN026 putative transposase YP_002410908.1 151283 D 585056 CDS YP_002410909.1 218703390 7158271 complement(152593..153444) 1 NC_011751.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 153444 panC 7158271 panC Escherichia coli UMN026 pantoate--beta-alanine ligase YP_002410909.1 152593 R 585056 CDS YP_002410910.1 218703391 7157378 complement(153456..154250) 1 NC_011751.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 154250 panB 7157378 panB Escherichia coli UMN026 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002410910.1 153456 R 585056 CDS YP_002410911.1 218703392 7157377 complement(154364..155614) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative fimbrial-like adhesin protein 155614 7157377 ECUMN_0133 Escherichia coli UMN026 putative fimbrial-like adhesin protein YP_002410911.1 154364 R 585056 CDS YP_002410912.1 218703393 7154612 complement(155666..156265) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative fimbrial protein 156265 7154612 ECUMN_0134 Escherichia coli UMN026 putative fimbrial protein YP_002410912.1 155666 R 585056 CDS YP_002410913.1 218703394 7154613 complement(156279..156839) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 156839 7154613 ECUMN_0135 Escherichia coli UMN026 hypothetical protein YP_002410913.1 156279 R 585056 CDS YP_002410914.1 218703395 7154614 complement(156858..159533) 1 NC_011751.1 similar to the fimbrial usher protein PapC; putative outer membrane usher protein 159533 7154614 ECUMN_0136 Escherichia coli UMN026 putative outer membrane usher protein YP_002410914.1 156858 R 585056 CDS YP_002410915.1 218703396 7154615 complement(159493..160224) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8102362, 8202364, 9278503; Product type f : factor; putative chaperone protein EcpD 160224 7154615 ECUMN_0137 Escherichia coli UMN026 putative chaperone protein EcpD YP_002410915.1 159493 R 585056 CDS YP_002410916.1 218703397 7154616 complement(160317..160913) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 160913 7154616 ECUMN_0138 Escherichia coli UMN026 hypothetical protein YP_002410916.1 160317 R 585056 CDS YP_002410917.1 218703398 7154617 complement(161238..161717) 1 NC_011751.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase 161717 folK 7154617 folK Escherichia coli UMN026 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase YP_002410917.1 161238 R 585056 CDS YP_002410918.1 218703399 7156428 complement(161714..163132) 1 NC_011751.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 163132 pcnB 7156428 pcnB Escherichia coli UMN026 poly(A) polymerase I YP_002410918.1 161714 R 585056 CDS YP_002410919.1 218703400 7157398 complement(163171..164097) 1 NC_011751.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA (Asp) synthetase 164097 yadB 7157398 yadB Escherichia coli UMN026 glutamyl-Q tRNA (Asp) synthetase YP_002410919.1 163171 R 585056 CDS YP_002410920.1 218703401 7158270 complement(164134..164589) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator; RNA polymerase-binding transcription factor 164589 dksA 7158270 dksA Escherichia coli UMN026 RNA polymerase-binding transcription factor YP_002410920.1 164134 R 585056 CDS YP_002410921.1 218703402 7156177 complement(164767..165471) 1 NC_011751.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 165471 sfsA 7156177 sfsA Escherichia coli UMN026 sugar fermentation stimulation protein A YP_002410921.1 164767 R 585056 CDS YP_002410922.1 218703403 7157909 complement(165486..166016) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97094878; Product type e : enzyme; 2'-5' RNA ligase 166016 ligT 7157909 ligT Escherichia coli UMN026 2'-5' RNA ligase YP_002410922.1 165486 R 585056 CDS YP_002410923.1 218703404 7156981 166090..168519 1 NC_011751.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 168519 hrpB 7156981 hrpB Escherichia coli UMN026 ATP-dependent RNA helicase HrpB YP_002410923.1 166090 D 585056 CDS YP_002410924.1 218703405 7156713 168613..171147 1 NC_011751.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 171147 mrcB 7156713 mrcB Escherichia coli UMN026 penicillin-binding protein 1b YP_002410924.1 168613 D 585056 CDS YP_002410925.1 218703406 7157176 171367..173625 1 NC_011751.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 173625 fhuA 7157176 fhuA Escherichia coli UMN026 ferrichrome outer membrane transporter YP_002410925.1 171367 D 585056 CDS YP_002410926.1 218703407 7156344 173676..174473 1 NC_011751.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 174473 fhuC 7156344 fhuC Escherichia coli UMN026 iron-hydroxamate transporter ATP-binding subunit YP_002410926.1 173676 D 585056 CDS YP_002410927.1 218703408 7156346 174473..175363 1 NC_011751.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 175363 fhuD 7156346 fhuD Escherichia coli UMN026 iron-hydroxamate transporter substrate-binding subunit YP_002410927.1 174473 D 585056 CDS YP_002410928.1 218703409 7156347 175360..177342 1 NC_011751.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate permease 177342 fhuB 7156347 fhuB Escherichia coli UMN026 iron-hydroxamate permease YP_002410928.1 175360 D 585056 CDS YP_002410929.1 218703410 7156345 complement(177377..178657) 1 NC_011751.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 178657 hemL 7156345 hemL Escherichia coli UMN026 glutamate-1-semialdehyde aminotransferase YP_002410929.1 177377 R 585056 CDS YP_002410930.1 218703411 7156658 178882..180303 1 NC_011751.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 180303 clcA 7156658 clcA Escherichia coli UMN026 chloride channel protein YP_002410930.1 178882 D 585056 CDS YP_002410931.1 218703412 7155975 180385..180729 1 NC_011751.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 180729 yadR 7155975 yadR Escherichia coli UMN026 iron-sulfur cluster insertion protein ErpA YP_002410931.1 180385 D 585056 CDS YP_002410932.1 218703413 7158276 complement(180776..181399) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 181399 yadS 7158276 yadS Escherichia coli UMN026 hypothetical protein YP_002410932.1 180776 R 585056 CDS YP_002410933.1 218703414 7158277 complement(181437..182237) 1 NC_011751.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 182237 btuF 7158277 btuF Escherichia coli UMN026 vitamin B12-transporter protein BtuF YP_002410933.1 181437 R 585056 CDS YP_002410934.1 218703415 7155898 complement(182230..182928) 1 NC_011751.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 182928 pfs 7155898 pfs Escherichia coli UMN026 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002410934.1 182230 R 585056 CDS YP_002410935.1 218703416 7157425 183012..184529 1 NC_011751.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 184529 dgt 7157425 dgt Escherichia coli UMN026 deoxyguanosinetriphosphate triphosphohydrolase YP_002410935.1 183012 D 585056 CDS YP_002410936.1 218703417 7156155 184659..186083 1 NC_011751.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 186083 degP 7156155 degP Escherichia coli UMN026 serine endoprotease YP_002410936.1 184659 D 585056 CDS YP_002410937.1 218703418 7156137 186238..187395 1 NC_011751.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 187395 cdaR 7156137 cdaR Escherichia coli UMN026 carbohydrate diacid transcriptional activator CdaR YP_002410937.1 186238 D 585056 CDS YP_002410938.1 218703419 7155936 complement(187449..187835) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 187835 yaeH 7155936 yaeH Escherichia coli UMN026 hypothetical protein YP_002410938.1 187449 R 585056 CDS YP_002410939.1 218703420 7158280 complement(188148..188972) 1 NC_011751.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 188972 dapD 7158280 dapD Escherichia coli UMN026 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002410939.1 188148 R 585056 CDS YP_002410940.1 218703421 7156109 complement(189003..191675) 1 NC_011751.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 191675 glnD 7156109 glnD Escherichia coli UMN026 PII uridylyl-transferase YP_002410940.1 189003 R 585056 CDS YP_002410941.1 218703422 7156550 complement(191737..192531) 1 NC_011751.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 192531 map 7156550 map Escherichia coli UMN026 methionine aminopeptidase YP_002410941.1 191737 R 585056 CDS YP_002410942.1 218703423 7158016 192899..193624 1 NC_011751.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 193624 rpsB 7158016 rpsB Escherichia coli UMN026 30S ribosomal protein S2 YP_002410942.1 192899 D 585056 CDS YP_002410943.1 218703424 7157768 193882..194733 1 NC_011751.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 194733 tsf 7157768 tsf Escherichia coli UMN026 elongation factor Ts YP_002410943.1 193882 D 585056 CDS YP_002410944.1 218703425 7158132 194880..195605 1 NC_011751.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 195605 pyrH 7158132 pyrH Escherichia coli UMN026 uridylate kinase YP_002410944.1 194880 D 585056 CDS YP_002410945.1 218703426 7157603 195897..196454 1 NC_011751.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 196454 frr 7157603 frr Escherichia coli UMN026 ribosome recycling factor YP_002410945.1 195897 D 585056 CDS YP_002410946.1 218703427 7156443 196546..197742 1 NC_011751.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 197742 dxr 7156443 dxr Escherichia coli UMN026 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002410946.1 196546 D 585056 CDS YP_002410947.1 218703428 7156215 197928..198689 1 NC_011751.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 198689 ispU 7156215 ispU Escherichia coli UMN026 undecaprenyl pyrophosphate synthase YP_002410947.1 197928 D 585056 CDS YP_002410948.1 218703429 7156869 198702..199559 1 NC_011751.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 199559 cdsA 7156869 cdsA Escherichia coli UMN026 CDP-diglyceride synthase YP_002410948.1 198702 D 585056 CDS YP_002410949.1 218703430 7155939 199571..200923 1 NC_011751.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 200923 yaeL 7155939 yaeL Escherichia coli UMN026 zinc metallopeptidase RseP YP_002410949.1 199571 D 585056 CDS YP_002410950.1 218703431 7158282 200953..203385 1 NC_011751.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 203385 yaeT 7158282 yaeT Escherichia coli UMN026 outer membrane protein assembly factor YaeT YP_002410950.1 200953 D 585056 CDS YP_002410951.1 218703432 7158286 203507..203992 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor; periplasmic chaperone 203992 hlpA 7158286 hlpA Escherichia coli UMN026 periplasmic chaperone YP_002410951.1 203507 D 585056 CDS YP_002410952.1 218703433 7156687 203996..205021 1 NC_011751.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 205021 lpxD 7156687 lpxD Escherichia coli UMN026 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002410952.1 203996 D 585056 CDS YP_002410953.1 218703434 7157012 205126..205581 1 NC_011751.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 205581 fabZ 7157012 fabZ Escherichia coli UMN026 (3R)-hydroxymyristoyl-ACP dehydratase YP_002410953.1 205126 D 585056 CDS YP_002410954.1 218703435 7156301 205585..206373 1 NC_011751.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 206373 lpxA 7156301 lpxA Escherichia coli UMN026 UDP-N-acetylglucosamine acyltransferase YP_002410954.1 205585 D 585056 CDS YP_002410955.1 218703436 7157009 206373..207521 1 NC_011751.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 207521 lpxB 7157009 lpxB Escherichia coli UMN026 lipid-A-disaccharide synthase YP_002410955.1 206373 D 585056 CDS YP_002410956.1 218703437 7157010 207518..208114 1 NC_011751.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 208114 rnhB 7157010 rnhB Escherichia coli UMN026 ribonuclease HII YP_002410956.1 207518 D 585056 CDS YP_002410957.1 218703438 7157714 208151..211633 1 NC_011751.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 211633 dnaE 7157714 dnaE Escherichia coli UMN026 DNA polymerase III subunit alpha YP_002410957.1 208151 D 585056 CDS YP_002410958.1 218703439 7156186 211646..212605 1 NC_011751.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 212605 accA 7156186 accA Escherichia coli UMN026 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002410958.1 211646 D 585056 CDS YP_002410959.1 218703440 7155671 212704..214845 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme; lysine decarboxylase 2, constitutive 214845 ldcC 7155671 ldcC Escherichia coli UMN026 lysine decarboxylase 2, constitutive YP_002410959.1 212704 D 585056 CDS YP_002410960.1 218703441 7156936 214902..215291 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 215291 yaeR 7156936 yaeR Escherichia coli UMN026 hypothetical protein YP_002410960.1 214902 D 585056 CDS YP_002410961.1 218703442 7158285 215356..216651 1 NC_011751.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA (Ile)-lysidine synthetase 216651 tilS 7158285 tilS Escherichia coli UMN026 tRNA (Ile)-lysidine synthetase YP_002410961.1 215356 D 585056 CDS YP_002410962.1 218703443 7158072 complement(216700..216954) 1 NC_011751.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 216954 rof 7158072 rof Escherichia coli UMN026 Rho-binding antiterminator YP_002410962.1 216700 R 585056 CDS YP_002410963.1 218703444 7157721 complement(216947..217147) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 217147 yaeP 7157721 yaeP Escherichia coli UMN026 hypothetical protein YP_002410963.1 216947 R 585056 CDS YP_002410964.1 218703445 7158283 217313..217858 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 217858 yaeQ 7158283 yaeQ Escherichia coli UMN026 hypothetical protein YP_002410964.1 217313 D 585056 CDS YP_002410965.1 218703446 7158284 217855..218277 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; peptidyl-tRNA hydrolase domain protein 218277 yaeJ 7158284 yaeJ Escherichia coli UMN026 peptidyl-tRNA hydrolase domain protein YP_002410965.1 217855 D 585056 CDS YP_002410966.1 218703447 7158281 218291..219001 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein; lipoprotein involved with copper homeostasis and adhesion 219001 nlpE 7158281 nlpE Escherichia coli UMN026 lipoprotein involved with copper homeostasis and adhesion YP_002410966.1 218291 D 585056 CDS YP_002410967.1 218703448 7157289 complement(219031..219855) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 219855 yaeF 7157289 yaeF Escherichia coli UMN026 hypothetical protein YP_002410967.1 219031 R 585056 CDS YP_002410968.1 218703449 7158279 complement(219908..221626) 1 NC_011751.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 221626 proS 7158279 proS Escherichia coli UMN026 prolyl-tRNA synthetase YP_002410968.1 219908 R 585056 CDS YP_002410969.1 218703450 7157535 complement(221737..222444) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 222444 yaeB 7157535 yaeB Escherichia coli UMN026 hypothetical protein YP_002410969.1 221737 R 585056 CDS YP_002410970.1 218703451 7158278 complement(222441..222845) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : putative regulator; outer membrane lipoprotein 222845 rcsF 7158278 rcsF Escherichia coli UMN026 outer membrane lipoprotein YP_002410970.1 222441 R 585056 CDS YP_002410971.1 218703452 7157632 complement(222963..223778) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter; DL-methionine transporter substrate-binding subunit 223778 metQ 7157632 metQ Escherichia coli UMN026 DL-methionine transporter substrate-binding subunit YP_002410971.1 222963 R 585056 CDS YP_002410972.1 218703453 7157112 complement(223818..224471) 1 NC_011751.1 part of the MetNIQ methionine uptake system; DL-methionine permease 224471 metI 7157112 metI Escherichia coli UMN026 DL-methionine permease YP_002410972.1 223818 R 585056 CDS YP_002410973.1 218703454 7157107 complement(224464..225495) 1 NC_011751.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 225495 metN 7157107 metN Escherichia coli UMN026 DL-methionine transporter ATP-binding subunit YP_002410973.1 224464 R 585056 CDS YP_002410974.1 218703455 7157111 225683..226255 1 NC_011751.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 226255 gmhB 7157111 gmhB Escherichia coli UMN026 D,D-heptose 1,7-bisphosphate phosphatase YP_002410974.1 225683 D 585056 CDS YP_002410975.1 218703456 7155587 232018..232821 1 NC_011751.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 232821 dkgB 7155587 dkgB Escherichia coli UMN026 2,5-diketo-D-gluconate reductase B YP_002410975.1 232018 D 585056 CDS YP_002410976.1 218703457 7156176 complement(232818..233732) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 233732 yafC 7156176 yafC Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002410976.1 232818 R 585056 CDS YP_002410977.1 218703458 7158287 233973..234773 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890; hypothetical protein 234773 yafD 7158287 yafD Escherichia coli UMN026 hypothetical protein YP_002410977.1 233973 D 585056 CDS YP_002410978.1 218703459 7158288 234850..235620 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 235620 yafE 7158288 yafE Escherichia coli UMN026 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002410978.1 234850 D 585056 CDS YP_002410979.1 218703460 7158289 complement(235668..237026) 1 NC_011751.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 237026 mltD 7158289 mltD Escherichia coli UMN026 membrane-bound lytic murein transglycosylase D YP_002410979.1 235668 R 585056 CDS YP_002410980.1 218703461 7157142 complement(237098..237853) 1 NC_011751.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 237853 gloB 7157142 gloB Escherichia coli UMN026 hydroxyacylglutathione hydrolase YP_002410980.1 237098 R 585056 CDS YP_002410981.1 218703462 7156560 237887..238609 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 238609 yafS 7156560 yafS Escherichia coli UMN026 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002410981.1 237887 D 585056 CDS YP_002410982.1 218703463 7158298 complement(238606..239073) 1 NC_011751.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 239073 rnhA 7158298 rnhA Escherichia coli UMN026 ribonuclease H YP_002410982.1 238606 R 585056 CDS YP_002410983.1 218703464 7157713 239138..239869 1 NC_011751.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 239869 dnaQ 7157713 dnaQ Escherichia coli UMN026 DNA polymerase III subunit epsilon YP_002410983.1 239138 D 585056 CDS YP_002410984.1 218703465 7155598 240405..241190 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aminopeptidase 241190 yafT 7155598 yafT Escherichia coli UMN026 putative aminopeptidase YP_002410984.1 240405 D 585056 CDS YP_002410985.1 218703466 7158299 complement(241530..242009) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 242009 7158299 ECUMN_0214 Escherichia coli UMN026 hypothetical protein YP_002410985.1 241530 R 585056 CDS YP_002410986.1 218703467 7154618 complement(242027..243526) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 243526 7154618 ECUMN_0215 Escherichia coli UMN026 hypothetical protein YP_002410986.1 242027 R 585056 CDS YP_002410987.1 218703468 7154619 complement(243396..246923) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 246923 7154619 ECUMN_0216 Escherichia coli UMN026 hypothetical protein YP_002410987.1 243396 R 585056 CDS YP_002410988.1 218703469 7154620 complement(246943..248451) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 248451 7154620 ECUMN_0217 Escherichia coli UMN026 hypothetical protein YP_002410988.1 246943 R 585056 CDS YP_002410989.1 218703470 7154621 complement(248390..249133) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 249133 7154621 ECUMN_0218 Escherichia coli UMN026 hypothetical protein YP_002410989.1 248390 R 585056 CDS YP_002410990.1 218703471 7154622 complement(249130..251862) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity 251862 7154622 ECUMN_0219 Escherichia coli UMN026 putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity YP_002410990.1 249130 R 585056 CDS YP_002410991.1 218703472 7154623 complement(251872..252645) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 252645 7154623 ECUMN_0220 Escherichia coli UMN026 hypothetical protein YP_002410991.1 251872 R 585056 CDS YP_002410992.1 218703473 7154624 complement(252650..253996) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 253996 7154624 ECUMN_0221 Escherichia coli UMN026 hypothetical protein YP_002410992.1 252650 R 585056 CDS YP_002410993.1 218703474 7154625 complement(253999..254523) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 254523 7154625 ECUMN_0222 Escherichia coli UMN026 hypothetical protein YP_002410993.1 253999 R 585056 CDS YP_002410994.1 218703475 7154626 complement(254520..255908) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 255908 7154626 ECUMN_0223 Escherichia coli UMN026 hypothetical protein YP_002410994.1 254520 R 585056 CDS YP_002410995.1 218703476 7154627 complement(255817..256866) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 256866 7154627 ECUMN_0224 Escherichia coli UMN026 hypothetical protein YP_002410995.1 255817 R 585056 CDS YP_002410996.1 218703477 7154628 complement(256830..258689) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 258689 7154628 ECUMN_0225 Escherichia coli UMN026 hypothetical protein YP_002410996.1 256830 R 585056 CDS YP_002410997.1 218703478 7154629 complement(258677..259102) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 259102 7154629 ECUMN_0226 Escherichia coli UMN026 hypothetical protein YP_002410997.1 258677 R 585056 CDS YP_002410998.1 218703479 7154630 complement(259107..260591) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 260591 7154630 ECUMN_0227 Escherichia coli UMN026 hypothetical protein YP_002410998.1 259107 R 585056 CDS YP_002410999.1 218703480 7154631 complement(260614..261117) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 261117 7154631 ECUMN_0228 Escherichia coli UMN026 hypothetical protein YP_002410999.1 260614 R 585056 CDS YP_002411000.1 218703481 7154632 261820..262338 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 262338 7154632 ECUMN_0229 Escherichia coli UMN026 hypothetical protein YP_002411000.1 261820 D 585056 CDS YP_002411001.1 218703482 7154633 262559..264517 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative VgrG/E protein 264517 7154633 ECUMN_0230 Escherichia coli UMN026 putative VgrG/E protein YP_002411001.1 262559 D 585056 CDS YP_002411002.1 218703483 7154634 264514..265356 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 265356 7154634 ECUMN_0231 Escherichia coli UMN026 hypothetical protein YP_002411002.1 264514 D 585056 CDS YP_002411003.1 218703484 7154635 265378..266949 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 266949 7154635 ECUMN_0232 Escherichia coli UMN026 hypothetical protein YP_002411003.1 265378 D 585056 CDS YP_002411004.1 218703485 7154636 267016..268026 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 268026 7154636 ECUMN_0233 Escherichia coli UMN026 hypothetical protein YP_002411004.1 267016 D 585056 CDS YP_002411005.1 218703486 7154637 268336..269295 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase 269295 yhhI 7154637 yhhI Escherichia coli UMN026 putative transposase YP_002411005.1 268336 D 585056 CDS YP_002411006.1 218703487 7159174 complement(269323..269463) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 269463 7159174 ECUMN_0235 Escherichia coli UMN026 hypothetical protein YP_002411006.1 269323 R 585056 CDS YP_002411007.1 218703488 7154638 269827..271077 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative reverse transcriptase 271077 7154638 ECUMN_0236 Escherichia coli UMN026 putative reverse transcriptase YP_002411007.1 269827 D 585056 CDS YP_002411008.1 218703489 7154639 271524..272660 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase 272660 yhhI 7154639 yhhI Escherichia coli UMN026 putative transposase YP_002411008.1 271524 D 585056 CDS YP_002411009.1 218703490 7159175 272780..273283 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 273283 7159175 ECUMN_0238 Escherichia coli UMN026 hypothetical protein YP_002411009.1 272780 D 585056 CDS YP_002411010.1 218703491 7154640 273350..273862 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 273862 7154640 ECUMN_0239 Escherichia coli UMN026 hypothetical protein YP_002411010.1 273350 D 585056 CDS YP_002411011.1 218703492 7154641 complement(274134..274904) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : putative enzyme; hypothetical protein 274904 yafV 7154641 yafV Escherichia coli UMN026 hypothetical protein YP_002411011.1 274134 R 585056 CDS YP_002411012.1 218703493 7158300 275058..275531 1 NC_011751.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 275531 ivy 7158300 ivy Escherichia coli UMN026 C-lysozyme inhibitor YP_002411012.1 275058 D 585056 CDS YP_002411013.1 218703494 7156880 complement(275574..278018) 1 NC_011751.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 278018 fadE 7156880 fadE Escherichia coli UMN026 acyl-CoA dehydrogenase YP_002411013.1 275574 R 585056 CDS YP_002411014.1 218703495 7156305 278258..278836 1 NC_011751.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 278836 gmhA 7156305 gmhA Escherichia coli UMN026 phosphoheptose isomerase YP_002411014.1 278258 D 585056 CDS YP_002411015.1 218703496 7157000 279042..279809 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutamine amidotransferases class-II 279809 yafJ 7157000 yafJ Escherichia coli UMN026 putative glutamine amidotransferases class-II YP_002411015.1 279042 D 585056 CDS YP_002411016.1 218703497 7158290 complement(279780..280520) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 280520 yafK 7158290 yafK Escherichia coli UMN026 hypothetical protein YP_002411016.1 279780 R 585056 CDS YP_002411017.1 218703498 7158291 280812..281570 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported hydrolase 281570 yafL 7158291 yafL Escherichia coli UMN026 putative exported hydrolase YP_002411017.1 280812 D 585056 CDS YP_002411018.1 218703499 7158292 281747..282244 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 282244 yafM 7158292 yafM Escherichia coli UMN026 hypothetical protein YP_002411018.1 281747 D 585056 CDS YP_002411019.1 218703500 7158293 complement(282403..283449) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family 283449 7158293 ECUMN_0248 Escherichia coli UMN026 transposase ORF B, IS3 family YP_002411019.1 282403 R 585056 CDS YP_002411020.1 218703501 7154642 complement(283269..283616) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family 283616 7154642 ECUMN_0249 Escherichia coli UMN026 transposase ORF A, IS3 family YP_002411020.1 283269 R 585056 CDS YP_002411021.1 218703502 7154643 complement(283944..286037) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7783646, 15687208; Product type s : structure; flagellar system protein 286037 fhiA 7154643 fhiA Escherichia coli UMN026 flagellar system protein YP_002411021.1 283944 R 585056 CDS YP_002411022.1 218703503 7156342 complement(286021..287160) 1 NC_011751.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 287160 flhB 7156342 flhB Escherichia coli UMN026 flagellar biosynthesis protein FlhB YP_002411022.1 286021 R 585056 CDS YP_002411023.1 218703504 7156964 complement(287150..287932) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type pt : putative transporter; Flagellar biosynthetic protein fliR 287932 lfiR 7156964 lfiR Escherichia coli UMN026 Flagellar biosynthetic protein fliR YP_002411023.1 287150 R 585056 CDS YP_002411024.1 218703505 7156974 complement(287934..288206) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar export/assembly FliQ-like protein 288206 lfiQ 7156974 lfiQ Escherichia coli UMN026 lateral flagellar export/assembly FliQ-like protein YP_002411024.1 287934 R 585056 CDS YP_002411025.1 218703506 7156973 complement(288209..288961) 1 NC_011751.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 288961 fliP 7156973 fliP Escherichia coli UMN026 flagellar biosynthesis protein FliP YP_002411025.1 288209 R 585056 CDS YP_002411026.1 218703507 7156972 complement(288958..289329) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type cp : cell process; lateral flagellar motor switch C ring FliN-like protein 289329 lfiN 7156972 lfiN Escherichia coli UMN026 lateral flagellar motor switch C ring FliN-like protein YP_002411026.1 288958 R 585056 CDS YP_002411027.1 218703508 7156971 complement(289322..290173) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type cp : cell process; lateral flagellar motor switch C-ring FliM-like protein 290173 lfiM 7156971 lfiM Escherichia coli UMN026 lateral flagellar motor switch C-ring FliM-like protein YP_002411027.1 289322 R 585056 CDS YP_002411028.1 218703509 7156970 290561..291541 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar RpoN-interacting regulatory protein 291541 lafK 7156970 lafK Escherichia coli UMN026 lateral flagellar RpoN-interacting regulatory protein YP_002411028.1 290561 D 585056 CDS YP_002411029.1 218703510 7156929 291556..291897 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar basal body component FliE-like protein 291897 lfiE 7156929 lfiE Escherichia coli UMN026 lateral flagellar basal body component FliE-like protein YP_002411029.1 291556 D 585056 CDS YP_002411030.1 218703511 7156965 291902..293548 1 NC_011751.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar MS-ring protein 293548 fliF 7156965 fliF Escherichia coli UMN026 flagellar MS-ring protein YP_002411030.1 291902 D 585056 CDS YP_002411031.1 218703512 7156966 293526..294536 1 NC_011751.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 294536 fliG 7156966 fliG Escherichia coli UMN026 flagellar motor switch protein G YP_002411031.1 293526 D 585056 CDS YP_002411032.1 218703513 7156967 294539..295249 1 NC_011751.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 295249 fliH 7156967 fliH Escherichia coli UMN026 flagellar assembly protein H YP_002411032.1 294539 D 585056 CDS YP_002411033.1 218703514 7156968 295242..296579 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type e : enzyme; lateral flagellar export/assembly protein 296579 lgiI 7156968 lgiI Escherichia coli UMN026 lateral flagellar export/assembly protein YP_002411033.1 295242 D 585056 CDS YP_002411034.1 218703515 7156976 296582..297016 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar export/assembly LfiJ-like protein 297016 lfiJ 7156976 lfiJ Escherichia coli UMN026 lateral flagellar export/assembly LfiJ-like protein YP_002411034.1 296582 D 585056 CDS YP_002411035.1 218703516 7156969 297019..297423 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11882717, 1906926, 8393871, 9182537, 11487587, 10508782, 15687208; Product type e : enzyme; glycerol-3-phosphate cytidylyltransferase 297423 7156969 ECUMN_0264 Escherichia coli UMN026 glycerol-3-phosphate cytidylyltransferase YP_002411035.1 297019 D 585056 CDS YP_002411036.1 218703517 7154644 complement(297567..300110) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type pe : putative enzyme; putative glysosyltransferase 300110 7154644 ECUMN_0265 Escherichia coli UMN026 putative glysosyltransferase YP_002411036.1 297567 R 585056 CDS YP_002411037.1 218703518 7154645 complement(300217..301185) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type pe : putative enzyme; putative lysine-N-methylase 301185 lafV 7154645 lafV Escherichia coli UMN026 putative lysine-N-methylase YP_002411037.1 300217 R 585056 CDS YP_002411038.1 218703519 7156931 complement(301273..301701) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FlgN-like protein 301701 lfgN 7156931 lfgN Escherichia coli UMN026 lateral flagellar chaperone FlgN-like protein YP_002411038.1 301273 R 585056 CDS YP_002411039.1 218703520 7156963 complement(301714..301992) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar anti-sigma factor 28 FlgM-like protein 301992 lfgM 7156963 lfgM Escherichia coli UMN026 lateral flagellar anti-sigma factor 28 FlgM-like protein YP_002411039.1 301714 R 585056 CDS YP_002411040.1 218703521 7156962 complement(302073..302810) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar P-ring addition FlgA-like protein 302810 lfgA 7156962 lfgA Escherichia coli UMN026 lateral flagellar P-ring addition FlgA-like protein YP_002411040.1 302073 R 585056 CDS YP_002411041.1 218703522 7156951 302862..303227 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2129540, 15687208; Product type s : structure; lateral flagellar rod FlgB-like protein 303227 lfgB 7156951 lfgB Escherichia coli UMN026 lateral flagellar rod FlgB-like protein YP_002411041.1 302862 D 585056 CDS YP_002411042.1 218703523 7156952 303230..303661 1 NC_011751.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar basal body rod protein FlgC 303661 flgC 7156952 flgC Escherichia coli UMN026 flagellar basal body rod protein FlgC YP_002411042.1 303230 D 585056 CDS YP_002411043.1 218703524 7156953 303661..304374 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar rod FlgD-like protein 304374 lfdD 7156953 lfdD Escherichia coli UMN026 lateral flagellar rod FlgD-like protein YP_002411043.1 303661 D 585056 CDS YP_002411044.1 218703525 7156950 304518..305720 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook FlgE-like protein 305720 lfgE 7156950 lfgE Escherichia coli UMN026 lateral flagellar hook FlgE-like protein YP_002411044.1 304518 D 585056 CDS YP_002411045.1 218703526 7156954 305720..306457 1 NC_011751.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 306457 flgF 7156954 flgF Escherichia coli UMN026 flagellar basal body rod protein FlgF YP_002411045.1 305720 D 585056 CDS YP_002411046.1 218703527 7156955 306510..307421 1 NC_011751.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 307421 flgG 7156955 flgG Escherichia coli UMN026 flagellar basal body rod protein FlgG YP_002411046.1 306510 D 585056 CDS YP_002411047.1 218703528 7156956 307628..308293 1 NC_011751.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH; flagellar basal body L-ring protein 308293 flgH 7156956 flgH Escherichia coli UMN026 flagellar basal body L-ring protein YP_002411047.1 307628 D 585056 CDS YP_002411048.1 218703529 7156957 308293..309408 1 NC_011751.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 309408 flgI 7156957 flgI Escherichia coli UMN026 flagellar basal body P-ring protein YP_002411048.1 308293 D 585056 CDS YP_002411049.1 218703530 7156958 309408..309707 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type e : enzyme; lateral flagellar peptidoglycan hydrolase FlgJ-like protein 309707 lfgJ 7156958 lfgJ Escherichia coli UMN026 lateral flagellar peptidoglycan hydrolase FlgJ-like protein YP_002411049.1 309408 D 585056 CDS YP_002411050.1 218703531 7156959 309883..311259 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FlgK-like protein 311259 lfgK 7156959 lfgK Escherichia coli UMN026 lateral flagellar hook associated FlgK-like protein YP_002411050.1 309883 D 585056 CDS YP_002411051.1 218703532 7156960 311274..312203 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FlgL-like protein 312203 lfgL 7156960 lfgL Escherichia coli UMN026 lateral flagellar hook associated FlgL-like protein YP_002411051.1 311274 D 585056 CDS YP_002411052.1 218703533 7156961 312220..313197 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type s : structure; putative lateral flagellar hook associated protein 313197 lafW 7156961 lafW Escherichia coli UMN026 putative lateral flagellar hook associated protein YP_002411052.1 312220 D 585056 CDS YP_002411053.1 218703534 7156932 313270..313614 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15687208; hypothetical protein 313614 7156932 ECUMN_0282 Escherichia coli UMN026 hypothetical protein YP_002411053.1 313270 D 585056 CDS YP_002411054.1 218703535 7154646 313624..313923 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type pr : putative regulator; transcriptional regulator 313923 7154646 ECUMN_0283 Escherichia coli UMN026 transcriptional regulator YP_002411054.1 313624 D 585056 CDS YP_002411055.1 218703536 7154647 complement(313981..314874) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type r : regulator; lateral flagellar transmembrane regulator 314874 lafZ 7154647 lafZ Escherichia coli UMN026 lateral flagellar transmembrane regulator YP_002411055.1 313981 R 585056 CDS YP_002411056.1 218703537 7156933 315243..316223 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellin FliC-like protein 316223 lafA 7156933 lafA Escherichia coli UMN026 lateral flagellin FliC-like protein YP_002411056.1 315243 D 585056 CDS YP_002411057.1 218703538 7156923 316428..317744 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook associated FliD-like protein 317744 lafB 7156923 lafB Escherichia coli UMN026 lateral flagellar hook associated FliD-like protein YP_002411057.1 316428 D 585056 CDS YP_002411058.1 218703539 7156924 317767..318159 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FliS-like protein 318159 lafC 7156924 lafC Escherichia coli UMN026 lateral flagellar chaperone FliS-like protein YP_002411058.1 317767 D 585056 CDS YP_002411059.1 218703540 7156925 318164..318475 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type f : factor; lateral flagellar chaperone FliT-like protein 318475 lafD 7156925 lafD Escherichia coli UMN026 lateral flagellar chaperone FliT-like protein YP_002411059.1 318164 D 585056 CDS YP_002411060.1 218703541 7156926 318472..319530 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; lateral flagellar hook length control FliK-like protein 319530 lafE 7156926 lafE Escherichia coli UMN026 lateral flagellar hook length control FliK-like protein YP_002411060.1 318472 D 585056 CDS YP_002411061.1 218703542 7156927 319538..320005 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15687208; Product type s : structure; lateral flagellar associated FliL-like protein 320005 lafF 7156927 lafF Escherichia coli UMN026 lateral flagellar associated FliL-like protein YP_002411061.1 319538 D 585056 CDS YP_002411062.1 218703543 7156928 320025..320741 1 NC_011751.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 320741 7156928 ECUMN_0291 Escherichia coli UMN026 flagellar biosynthesis sigma factor YP_002411062.1 320025 D 585056 CDS YP_002411063.1 218703544 7154648 320754..321617 1 NC_011751.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 321617 lafT 7154648 lafT Escherichia coli UMN026 flagellar motor protein MotA YP_002411063.1 320754 D 585056 CDS YP_002411064.1 218703545 7156930 321620..322543 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; hypothetical protein 322543 mbhA 7156930 mbhA Escherichia coli UMN026 hypothetical protein YP_002411064.1 321620 D 585056 CDS YP_002411065.1 218703546 7157065 322614..323669 1 NC_011751.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 323669 dinB 7157065 dinB Escherichia coli UMN026 DNA polymerase IV YP_002411065.1 322614 D 585056 CDS YP_002411066.1 218703547 7156166 323721..324014 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : putative factor; putative antitoxin of the YafO-YafN toxin-antitoxin system 324014 yafN 7156166 yafN Escherichia coli UMN026 putative antitoxin of the YafO-YafN toxin-antitoxin system YP_002411066.1 323721 D 585056 CDS YP_002411067.1 218703548 7158296 324425..324877 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : putative enzyme; hypothetical protein 324877 yafP 7158296 yafP Escherichia coli UMN026 hypothetical protein YP_002411067.1 324425 D 585056 CDS YP_002411068.1 218703549 7158297 325056..326207 1 NC_011751.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 326207 7158297 ECUMN_0299 Escherichia coli UMN026 hypothetical protein YP_002411068.1 325056 D 585056 CDS YP_002411069.1 218703550 7154649 326318..326818 1 NC_011751.1 similar to release factor 1 and 2; peptide chain release factor-like protein 326818 prfH 7154649 prfH Escherichia coli UMN026 peptide chain release factor-like protein YP_002411069.1 326318 D 585056 CDS YP_002411070.1 218703551 7157520 326826..327389 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 327389 7157520 ECUMN_0301 Escherichia coli UMN026 hypothetical protein YP_002411070.1 326826 D 585056 CDS YP_002411071.1 218703552 7154650 complement(327406..327687) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 327687 7154650 ECUMN_0302 Escherichia coli UMN026 hypothetical protein YP_002411071.1 327406 R 585056 CDS YP_002411072.1 218703553 7154651 complement(327696..329153) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme; aminoacyl-histidine dipeptidase 329153 pepD 7154651 pepD Escherichia coli UMN026 aminoacyl-histidine dipeptidase YP_002411072.1 327696 R 585056 CDS YP_002411073.1 218703554 7157412 329414..329872 1 NC_011751.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 329872 gpt 7157412 gpt Escherichia coli UMN026 xanthine-guanine phosphoribosyltransferase YP_002411073.1 329414 D 585056 CDS YP_002411074.1 218703555 7156608 329964..331208 1 NC_011751.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 331208 frsA 7156608 frsA Escherichia coli UMN026 fermentation/respiration switch protein YP_002411074.1 329964 D 585056 CDS YP_002411075.1 218703556 7156444 331266..331667 1 NC_011751.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 331667 crl 7156444 crl Escherichia coli UMN026 DNA-binding transcriptional regulator Crl YP_002411075.1 331266 D 585056 CDS YP_002411076.1 218703557 7156014 complement(331706..332761) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter; outer membrane phosphoporin protein E 332761 phoE 7156014 phoE Escherichia coli UMN026 outer membrane phosphoporin protein E YP_002411076.1 331706 R 585056 CDS YP_002411077.1 218703558 7157457 333049..334152 1 NC_011751.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 334152 proB 7157457 proB Escherichia coli UMN026 gamma-glutamyl kinase YP_002411077.1 333049 D 585056 CDS YP_002411078.1 218703559 7157531 334164..335417 1 NC_011751.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 335417 proA 7157531 proA Escherichia coli UMN026 gamma-glutamyl phosphate reductase YP_002411078.1 334164 D 585056 CDS YP_002411079.1 218703560 7158301 complement(336526..337410) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator 337410 7158301 ECUMN_0311 Escherichia coli UMN026 putative LysR-like transcriptional regulator YP_002411079.1 336526 R 585056 CDS YP_002411080.1 218703561 7154652 337576..338733 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 338733 7154652 ECUMN_0312 Escherichia coli UMN026 hypothetical protein YP_002411080.1 337576 D 585056 CDS YP_002411081.1 218703562 7154653 338809..340002 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1427017; Product type r : regulator; transcription regulatory protein opdE 340002 opdE 7154653 opdE Escherichia coli UMN026 transcription regulatory protein opdE YP_002411081.1 338809 D 585056 CDS YP_002411082.1 218703563 7157356 complement(340183..341139) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 341139 yagQ 7157356 yagQ Escherichia coli UMN026 hypothetical protein YP_002411082.1 340183 R 585056 CDS YP_002411083.1 218703564 7158302 complement(341149..343347) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 343347 yagR 7158302 yagR Escherichia coli UMN026 putative oxidoreductase YP_002411083.1 341149 R 585056 CDS YP_002411084.1 218703565 7158303 complement(343344..344300) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 344300 yagS 7158303 yagS Escherichia coli UMN026 putative oxidoreductase YP_002411084.1 343344 R 585056 CDS YP_002411085.1 218703566 7158305 344825..345172 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family 345172 7158305 ECUMN_0318 Escherichia coli UMN026 transposase ORF A, IS3 family YP_002411085.1 344825 D 585056 CDS YP_002411086.1 218703567 7154654 344992..346038 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family 346038 7154654 ECUMN_0319 Escherichia coli UMN026 transposase ORF B, IS3 family YP_002411086.1 344992 D 585056 CDS YP_002411087.1 218703568 7158306 346654..347268 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 347268 yagU 7158306 yagU Escherichia coli UMN026 hypothetical protein YP_002411087.1 346654 D 585056 CDS YP_002411088.1 218703569 7158307 complement(348160..348870) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 348870 yagV 7158307 yagV Escherichia coli UMN026 hypothetical protein YP_002411088.1 348160 R 585056 CDS YP_002411089.1 218703570 7158308 complement(348839..350482) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative surface or exported protein 350482 yagW 7158308 yagW Escherichia coli UMN026 putative surface or exported protein YP_002411089.1 348839 R 585056 CDS YP_002411090.1 218703571 7158309 complement(350472..352997) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 352997 yagX 7158309 yagX Escherichia coli UMN026 hypothetical protein YP_002411090.1 350472 R 585056 CDS YP_002411091.1 218703572 7158310 complement(353023..353691) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 353691 yagY 7158310 yagY Escherichia coli UMN026 hypothetical protein YP_002411091.1 353023 R 585056 CDS YP_002411092.1 218703573 7158311 complement(353749..354336) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 17563352, 11466275; Product type s : structure; common pilus ECP 354336 ecpA 7158311 ecpA Escherichia coli UMN026 common pilus ECP YP_002411092.1 353749 R 585056 CDS YP_002411093.1 218703574 7156225 complement(354411..355001) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 355001 ykgK 7156225 ykgK Escherichia coli UMN026 putative transcriptional regulator YP_002411093.1 354411 R 585056 CDS YP_002411094.1 218703575 7159455 complement(356178..356441) 1 NC_011751.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 356441 rpmE2 7159455 rpmE2 Escherichia coli UMN026 50S ribosomal protein L31 type B YP_002411094.1 356178 R 585056 CDS YP_002411095.1 218703576 7159456 complement(356495..356728) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 356728 7159456 ECUMN_0330 Escherichia coli UMN026 hypothetical protein YP_002411095.1 356495 R 585056 CDS YP_002411096.1 218703577 7154656 complement(357381..358523) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NADH-dependent flavin oxidoreductase 358523 7154656 ECUMN_0331 Escherichia coli UMN026 putative NADH-dependent flavin oxidoreductase YP_002411096.1 357381 R 585056 CDS YP_002411097.1 218703578 7154657 complement(358768..359688) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 359688 7154657 ECUMN_0332 Escherichia coli UMN026 hypothetical protein YP_002411097.1 358768 R 585056 CDS YP_002411098.1 218703579 7154658 359782..360771 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator 360771 7154658 ECUMN_0333 Escherichia coli UMN026 putative LysR-like transcriptional regulator YP_002411098.1 359782 D 585056 CDS YP_002411099.1 218703580 7154659 360954..361889 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR family transcriptional regulator 361889 7154659 ECUMN_0334 Escherichia coli UMN026 putative LysR family transcriptional regulator YP_002411099.1 360954 D 585056 CDS YP_002411100.1 218703581 7154660 complement(361920..362909) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldo-keto reductase 362909 7154660 ECUMN_0335 Escherichia coli UMN026 putative aldo-keto reductase YP_002411100.1 361920 R 585056 CDS YP_002411101.1 218703582 7154661 complement(362936..363787) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17575004; Product type pe : putative enzyme; putative aldo-keto reductase 363787 7154661 ECUMN_0336 Escherichia coli UMN026 putative aldo-keto reductase YP_002411101.1 362936 R 585056 CDS YP_002411102.1 218703583 7154662 364353..368606 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative adhesin 368606 7154662 ECUMN_0337 Escherichia coli UMN026 putative adhesin YP_002411102.1 364353 D 585056 CDS YP_002411103.1 218703584 7154663 complement(368727..369617) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator ykgA 369617 ykgA 7154663 ykgA Escherichia coli UMN026 putative transcriptional regulator ykgA YP_002411103.1 368727 R 585056 CDS YP_002411104.1 218703585 7159446 369817..370701 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative reductase 370701 7159446 ECUMN_0339 Escherichia coli UMN026 putative reductase YP_002411104.1 369817 D 585056 CDS YP_002411105.1 218703586 7154664 complement(370861..371454) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 371454 ykgB 7154664 ykgB Escherichia coli UMN026 hypothetical protein YP_002411105.1 370861 R 585056 CDS YP_002411106.1 218703587 7159447 complement(371466..371702) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 371702 ykgI 7159447 ykgI Escherichia coli UMN026 hypothetical protein YP_002411106.1 371466 R 585056 CDS YP_002411107.1 218703588 7159454 complement(371811..373136) 1 NC_011751.1 Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 373136 ykgC 7159454 ykgC Escherichia coli UMN026 pyridine nucleotide-disulfide oxidoreductase YP_002411107.1 371811 R 585056 CDS YP_002411108.1 218703589 7159448 373363..374217 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative AraC-type DNA-binding transcriptional regulator 374217 ykgD 7159448 ykgD Escherichia coli UMN026 putative AraC-type DNA-binding transcriptional regulator YP_002411108.1 373363 D 585056 CDS YP_002411109.1 218703590 7159449 374745..375464 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydroxyacid oxidoreductase (Fe-S centre) 375464 ykgE 7159449 ykgE Escherichia coli UMN026 putative hydroxyacid oxidoreductase (Fe-S centre) YP_002411109.1 374745 D 585056 CDS YP_002411110.1 218703591 7159450 375475..376902 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 376902 ykgF 7159450 ykgF Escherichia coli UMN026 putative oxidoreductase YP_002411110.1 375475 D 585056 CDS YP_002411111.1 218703592 7159451 376895..377590 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 377590 ykgG 7159451 ykgG Escherichia coli UMN026 hypothetical protein YP_002411111.1 376895 D 585056 CDS YP_002411112.1 218703593 7159452 complement(377664..377861) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 377861 7159452 ECUMN_0347 Escherichia coli UMN026 hypothetical protein YP_002411112.1 377664 R 585056 CDS YP_002411113.1 218703594 7154665 complement(377833..378501) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 378501 ykgH 7154665 ykgH Escherichia coli UMN026 hypothetical protein YP_002411113.1 377833 R 585056 CDS YP_002411114.1 218703595 7159453 complement(378712..380382) 1 NC_011751.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 380382 betA 7159453 betA Escherichia coli UMN026 choline dehydrogenase YP_002411114.1 378712 R 585056 CDS YP_002411115.1 218703596 7155867 complement(380396..381868) 1 NC_011751.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 381868 betB 7155867 betB Escherichia coli UMN026 betaine aldehyde dehydrogenase YP_002411115.1 380396 R 585056 CDS YP_002411116.1 218703597 7155868 complement(381882..382469) 1 NC_011751.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 382469 betI 7155868 betI Escherichia coli UMN026 transcriptional regulator BetI YP_002411116.1 381882 R 585056 CDS YP_002411117.1 218703598 7155869 382598..384631 1 NC_011751.1 proton-motive-force-driven choline transporter; choline transport protein BetT 384631 betT 7155869 betT Escherichia coli UMN026 choline transport protein BetT YP_002411117.1 382598 D 585056 CDS YP_002411118.1 218703599 7155870 complement(385000..385188) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 385188 7155870 ECUMN_0353 Escherichia coli UMN026 hypothetical protein YP_002411118.1 385000 R 585056 CDS YP_002411119.1 218703600 7154666 385508..386596 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995192; Product type e : enzyme; cyclic di-GMP phosphodiesterase 386596 yahA 7154666 yahA Escherichia coli UMN026 cyclic di-GMP phosphodiesterase YP_002411119.1 385508 D 585056 CDS YP_002411120.1 218703601 7158312 complement(386638..387570) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 387570 yahB 7158312 yahB Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411120.1 386638 R 585056 CDS YP_002411121.1 218703602 7158313 complement(387662..388159) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 388159 yahC 7158313 yahC Escherichia coli UMN026 hypothetical protein YP_002411121.1 387662 R 585056 CDS YP_002411122.1 218703603 7158314 388417..389022 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 389022 yahD 7158314 yahD Escherichia coli UMN026 hypothetical protein YP_002411122.1 388417 D 585056 CDS YP_002411123.1 218703604 7158315 389062..389925 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 389925 yahE 7158315 yahE Escherichia coli UMN026 hypothetical protein YP_002411123.1 389062 D 585056 CDS YP_002411124.1 218703605 7158316 389915..391462 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 391462 yahF 7158316 yahF Escherichia coli UMN026 hypothetical protein YP_002411124.1 389915 D 585056 CDS YP_002411125.1 218703606 7158317 391462..392880 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 392880 yahG 7158317 yahG Escherichia coli UMN026 hypothetical protein YP_002411125.1 391462 D 585056 CDS YP_002411126.1 218703607 7158318 392976..393926 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : putative enzyme; putative carbamate kinase 393926 yahI 7158318 yahI Escherichia coli UMN026 putative carbamate kinase YP_002411126.1 392976 D 585056 CDS YP_002411127.1 218703608 7158319 393936..395318 1 NC_011751.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; putative deaminase 395318 yahJ 7158319 yahJ Escherichia coli UMN026 putative deaminase YP_002411127.1 393936 D 585056 CDS YP_002411128.1 218703609 7158320 395580..396023 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 396023 7158320 ECUMN_0363 Escherichia coli UMN026 hypothetical protein YP_002411128.1 395580 D 585056 CDS YP_002411129.1 218703610 7154667 396274..397260 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter periplasmic binding protein 397260 7154667 ECUMN_0364 Escherichia coli UMN026 putative sugar ABC transporter periplasmic binding protein YP_002411129.1 396274 D 585056 CDS YP_002411130.1 218703611 7154668 397294..398793 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar ABC transporter ATP-binding protein 398793 7154668 ECUMN_0365 Escherichia coli UMN026 putative sugar ABC transporter ATP-binding protein YP_002411130.1 397294 D 585056 CDS YP_002411131.1 218703612 7154669 398786..399757 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sugar ABC transporter permease 399757 7154669 ECUMN_0366 Escherichia coli UMN026 putative sugar ABC transporter permease YP_002411131.1 398786 D 585056 CDS YP_002411132.1 218703613 7154670 399724..400710 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sugar ABC transporter permease 400710 7154670 ECUMN_0367 Escherichia coli UMN026 putative sugar ABC transporter permease YP_002411132.1 399724 D 585056 CDS YP_002411133.1 218703614 7154671 400797..401846 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 401846 yahK 7154671 yahK Escherichia coli UMN026 putative oxidoreductase YP_002411133.1 400797 D 585056 CDS YP_002411134.1 218703615 7158321 402089..402904 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 402904 yahL 7158321 yahL Escherichia coli UMN026 hypothetical protein YP_002411134.1 402089 D 585056 CDS YP_002411135.1 218703616 7155620 403317..403562 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 403562 yahM 7155620 yahM Escherichia coli UMN026 hypothetical protein YP_002411135.1 403317 D 585056 CDS YP_002411136.1 218703617 7158325 404397..404672 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 404672 yahO 7158325 yahO Escherichia coli UMN026 hypothetical protein YP_002411136.1 404397 D 585056 CDS YP_002411137.1 218703618 7158326 complement(404773..406359) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator; DNA-binding transcriptional activator 406359 prpR 7158326 prpR Escherichia coli UMN026 DNA-binding transcriptional activator YP_002411137.1 404773 R 585056 CDS YP_002411138.1 218703619 7157544 406598..407488 1 NC_011751.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 407488 prpB 7157544 prpB Escherichia coli UMN026 2-methylisocitrate lyase YP_002411138.1 406598 D 585056 CDS YP_002411139.1 218703620 7157540 408021..409190 1 NC_011751.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 409190 prpC 7157540 prpC Escherichia coli UMN026 methylcitrate synthase YP_002411139.1 408021 D 585056 CDS YP_002411140.1 218703621 7157541 409224..410675 1 NC_011751.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 410675 prpD 7157541 prpD Escherichia coli UMN026 2-methylcitrate dehydratase YP_002411140.1 409224 D 585056 CDS YP_002411141.1 218703622 7157542 410715..412601 1 NC_011751.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 412601 prpE 7157542 prpE Escherichia coli UMN026 propionyl-CoA synthetase YP_002411141.1 410715 D 585056 CDS YP_002411142.1 218703623 7157543 413502..414761 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter; cytosine permease 414761 codB 7157543 codB Escherichia coli UMN026 cytosine permease YP_002411142.1 413502 D 585056 CDS YP_002411143.1 218703624 7155996 414751..416034 1 NC_011751.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 416034 codA 7155996 codA Escherichia coli UMN026 cytosine deaminase YP_002411143.1 414751 D 585056 CDS YP_002411144.1 218703625 7155995 complement(416167..417066) 1 NC_011751.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source; DNA-binding transcriptional regulator CynR 417066 cynR 7155995 cynR Escherichia coli UMN026 DNA-binding transcriptional regulator CynR YP_002411144.1 416167 R 585056 CDS YP_002411145.1 218703626 7156069 417176..417835 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91242169, 92156106, 94075239, 3049588; Product type e : enzyme; carbonic anhydrase 417835 cynT 7156069 cynT Escherichia coli UMN026 carbonic anhydrase YP_002411145.1 417176 D 585056 CDS YP_002411146.1 218703627 7156071 417866..418336 1 NC_011751.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 418336 cynS 7156071 cynS Escherichia coli UMN026 cyanate hydratase YP_002411146.1 417866 D 585056 CDS YP_002411147.1 218703628 7156070 418369..419523 1 NC_011751.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter 419523 cynX 7156070 cynX Escherichia coli UMN026 putative cyanate transporter YP_002411147.1 418369 D 585056 CDS YP_002411148.1 218703629 7156072 complement(419611..420222) 1 NC_011751.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase 420222 lacA 7156072 lacA Escherichia coli UMN026 galactoside O-acetyltransferase YP_002411148.1 419611 R 585056 CDS YP_002411149.1 218703630 7156919 complement(420288..421541) 1 NC_011751.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 421541 lacY 7156919 lacY Escherichia coli UMN026 galactoside permease YP_002411149.1 420288 R 585056 CDS YP_002411150.1 218703631 7156921 complement(421593..424667) 1 NC_011751.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 424667 lacZ 7156921 lacZ Escherichia coli UMN026 beta-D-galactosidase YP_002411150.1 421593 R 585056 CDS YP_002411151.1 218703632 7156922 complement(424790..425872) 1 NC_011751.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 425872 lacI 7156922 lacI Escherichia coli UMN026 lac repressor YP_002411151.1 424790 R 585056 CDS YP_002411152.1 218703633 7156920 complement(425949..426896) 1 NC_011751.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR 426896 mhpR 7156920 mhpR Escherichia coli UMN026 DNA-binding transcriptional activator MhpR YP_002411152.1 425949 R 585056 CDS YP_002411153.1 218703634 7157126 426973..428637 1 NC_011751.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 428637 mhpA 7157126 mhpA Escherichia coli UMN026 3-(3-hydroxyphenyl)propionate hydroxylase YP_002411153.1 426973 D 585056 CDS YP_002411154.1 218703635 7157120 428639..429583 1 NC_011751.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 429583 mhpB 7157120 mhpB Escherichia coli UMN026 3-(2,3-dihydroxyphenyl)propionate dioxygenase YP_002411154.1 428639 D 585056 CDS YP_002411155.1 218703636 7157121 429586..430467 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87008429, 94002258, 15663942; Product type e : enzyme; 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 430467 mhpC 7157121 mhpC Escherichia coli UMN026 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase YP_002411155.1 429586 D 585056 CDS YP_002411156.1 218703637 7157122 430477..431286 1 NC_011751.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid; 2-keto-4-pentenoate hydratase 431286 mhpD 7157122 mhpD Escherichia coli UMN026 2-keto-4-pentenoate hydratase YP_002411156.1 430477 D 585056 CDS YP_002411157.1 218703638 7157123 431283..432233 1 NC_011751.1 catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 432233 mhpF 7157123 mhpF Escherichia coli UMN026 acetaldehyde dehydrogenase YP_002411157.1 431283 D 585056 CDS YP_002411158.1 218703639 7157125 432230..433243 1 NC_011751.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 433243 mhpE 7157125 mhpE Escherichia coli UMN026 4-hydroxy-2-ketovalerate aldolase YP_002411158.1 432230 D 585056 CDS YP_002411159.1 218703640 7157124 433419..434630 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7961399; Product type t : transporter; putative 3-hydroxyphenylpropionic transporter MhpT 434630 mhpT 7157124 mhpT Escherichia coli UMN026 putative 3-hydroxyphenylpropionic transporter MhpT YP_002411159.1 433419 D 585056 CDS YP_002411160.1 218703641 7157127 434731..435270 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme; nucleoprotein/polynucleotide-associated enzyme 435270 yaiL 7157127 yaiL Escherichia coli UMN026 nucleoprotein/polynucleotide-associated enzyme YP_002411160.1 434731 D 585056 CDS YP_002411161.1 218703642 7158332 complement(435395..436228) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800, 15466022; Product type e : enzyme; S-formylglutathione hydrolase 436228 frmB 7158332 frmB Escherichia coli UMN026 S-formylglutathione hydrolase YP_002411161.1 435395 R 585056 CDS YP_002411162.1 218703643 7156440 complement(436320..437429) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme; alcohol dehydrogenase 437429 frmA 7156440 frmA Escherichia coli UMN026 alcohol dehydrogenase YP_002411162.1 436320 R 585056 CDS YP_002411163.1 218703644 7156439 complement(437464..437739) 1 NC_011751.1 formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR 437739 frmR 7156439 frmR Escherichia coli UMN026 regulator protein FrmR YP_002411163.1 437464 R 585056 CDS YP_002411164.1 218703645 7156442 complement(437927..438700) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 438700 yaiO 7156442 yaiO Escherichia coli UMN026 hypothetical protein YP_002411164.1 437927 R 585056 CDS YP_002411165.1 218703646 7158333 complement(438702..439412) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transferase 439412 yaiX 7158333 yaiX Escherichia coli UMN026 putative transferase YP_002411165.1 438702 R 585056 CDS YP_002411166.1 218703647 7158338 complement(439261..440457) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated glycosyltransferase 440457 yaiP 7158338 yaiP Escherichia coli UMN026 putative membrane-associated glycosyltransferase YP_002411166.1 439261 R 585056 CDS YP_002411167.1 218703648 7158334 complement(440467..441138) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 441138 yaiS 7158334 yaiS Escherichia coli UMN026 hypothetical protein YP_002411167.1 440467 R 585056 CDS YP_002411168.1 218703649 7158335 441747..442709 1 NC_011751.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 442709 tauA 7158335 tauA Escherichia coli UMN026 taurine transporter substrate binding subunit YP_002411168.1 441747 D 585056 CDS YP_002411169.1 218703650 7158030 442722..443489 1 NC_011751.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 443489 tauB 7158030 tauB Escherichia coli UMN026 taurine transporter ATP-binding subunit YP_002411169.1 442722 D 585056 CDS YP_002411170.1 218703651 7158031 443486..444313 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter; taurine transporter subunit 444313 tauC 7158031 tauC Escherichia coli UMN026 taurine transporter subunit YP_002411170.1 443486 D 585056 CDS YP_002411171.1 218703652 7158032 444310..445161 1 NC_011751.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 445161 tauD 7158032 tauD Escherichia coli UMN026 taurine dioxygenase YP_002411171.1 444310 D 585056 CDS YP_002411172.1 218703653 7158033 complement(445201..446175) 1 NC_011751.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 446175 hemB 7158033 hemB Escherichia coli UMN026 delta-aminolevulinic acid dehydratase YP_002411172.1 445201 R 585056 CDS YP_002411173.1 218703654 7156651 446701..449607 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative flagellin-like structural protein 449607 7156651 ECUMN_0410 Escherichia coli UMN026 putative flagellin-like structural protein YP_002411173.1 446701 D 585056 CDS YP_002411174.1 218703655 7154672 449648..450316 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative DNA-binding transcriptional regulator 450316 yaiV 7154672 yaiV Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411174.1 449648 D 585056 CDS YP_002411175.1 218703656 7158336 complement(450317..451474) 1 NC_011751.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 451474 ampH 7158336 ampH Escherichia coli UMN026 beta-lactam binding protein AmpH YP_002411175.1 450317 R 585056 CDS YP_002411176.1 218703657 7155741 451612..451806 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 451806 7155741 ECUMN_0413 Escherichia coli UMN026 hypothetical protein YP_002411176.1 451612 D 585056 CDS YP_002411177.1 218703658 7154673 451826..453046 1 NC_011751.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 453046 sbmA 7154673 sbmA Escherichia coli UMN026 transport protein YP_002411177.1 451826 D 585056 CDS YP_002411178.1 218703659 7157874 453059..454153 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein 454153 yaiW 7157874 yaiW Escherichia coli UMN026 putative lipoprotein YP_002411178.1 453059 D 585056 CDS YP_002411179.1 218703660 7158337 complement(454211..454519) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 454519 yaiY 7158337 yaiY Escherichia coli UMN026 hypothetical protein YP_002411179.1 454211 R 585056 CDS YP_002411180.1 218703661 7158339 454647..454991 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 454991 yaiZ 7158339 yaiZ Escherichia coli UMN026 hypothetical protein YP_002411180.1 454647 D 585056 CDS YP_002411181.1 218703662 7158340 complement(455194..456288) 1 NC_011751.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 456288 ddl 7158340 ddl Escherichia coli UMN026 D-alanyl-alanine synthetase A YP_002411181.1 455194 R 585056 CDS YP_002411182.1 218703663 7156125 456366..456524 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 456524 7156125 ECUMN_0419 Escherichia coli UMN026 hypothetical protein YP_002411182.1 456366 D 585056 CDS YP_002411183.1 218703664 7154674 456750..457010 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 457010 yaiB 7154674 yaiB Escherichia coli UMN026 hypothetical protein YP_002411183.1 456750 D 585056 CDS YP_002411184.1 218703665 7158328 457110..458525 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; alkaline phosphatase 458525 phoA 7158328 phoA Escherichia coli UMN026 alkaline phosphatase YP_002411184.1 457110 D 585056 CDS YP_002411185.1 218703666 7157455 458644..458964 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor; hypothetical protein 458964 psiF 7157455 psiF Escherichia coli UMN026 hypothetical protein YP_002411185.1 458644 D 585056 CDS YP_002411186.1 218703667 7157549 459066..460181 1 NC_011751.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 460181 adrA 7157549 adrA Escherichia coli UMN026 diguanylate cyclase AdrA YP_002411186.1 459066 D 585056 CDS YP_002411187.1 218703668 7158329 complement(460198..461007) 1 NC_011751.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 461007 proC 7158329 proC Escherichia coli UMN026 pyrroline-5-carboxylate reductase YP_002411187.1 460198 R 585056 CDS YP_002411188.1 218703669 7157532 461127..461585 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 461585 yaiI 7157532 yaiI Escherichia coli UMN026 hypothetical protein YP_002411188.1 461127 D 585056 CDS YP_002411189.1 218703670 7158331 461768..462292 1 NC_011751.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 462292 aroL 7158331 aroL Escherichia coli UMN026 shikimate kinase II YP_002411189.1 461768 D 585056 CDS YP_002411190.1 218703671 7155792 462342..462533 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 462533 yaiA 7155792 yaiA Escherichia coli UMN026 hypothetical protein YP_002411190.1 462342 D 585056 CDS YP_002411191.1 218703672 7158327 462791..463468 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 86085675, 3001025; hypothetical protein 463468 aroM 7158327 aroM Escherichia coli UMN026 hypothetical protein YP_002411191.1 462791 D 585056 CDS YP_002411192.1 218703673 7155793 463540..463824 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 463824 yaiE 7155793 yaiE Escherichia coli UMN026 hypothetical protein YP_002411192.1 463540 D 585056 CDS YP_002411193.1 218703674 7158330 464032..464313 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 464313 ykiA 7158330 ykiA Escherichia coli UMN026 hypothetical protein YP_002411193.1 464032 D 585056 CDS YP_002411194.1 218703675 7159457 complement(464471..465382) 1 NC_011751.1 Required for efficient pilin antigenic variation; recombination associated protein 465382 rdgC 7159457 rdgC Escherichia coli UMN026 recombination associated protein YP_002411194.1 464471 R 585056 CDS YP_002411195.1 218703676 7157633 465507..466415 1 NC_011751.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 466415 mak 7157633 mak Escherichia coli UMN026 fructokinase YP_002411195.1 465507 D 585056 CDS YP_002411196.1 218703677 7157040 complement(466558..467742) 1 NC_011751.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ 467742 araJ 7157040 araJ Escherichia coli UMN026 MFS transport protein AraJ YP_002411196.1 466558 R 585056 CDS YP_002411197.1 218703678 7155765 complement(467868..471011) 1 NC_011751.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 471011 sbcC 7155765 sbcC Escherichia coli UMN026 exonuclease subunit SbcC YP_002411197.1 467868 R 585056 CDS YP_002411198.1 218703679 7157872 complement(471008..472210) 1 NC_011751.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 472210 sbcD 7157872 sbcD Escherichia coli UMN026 exonuclease subunit SbcD YP_002411198.1 471008 R 585056 CDS YP_002411199.1 218703680 7157873 472400..473089 1 NC_011751.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 473089 phoB 7157873 phoB Escherichia coli UMN026 transcriptional regulator PhoB YP_002411199.1 472400 D 585056 CDS YP_002411200.1 218703681 7157456 473147..474442 1 NC_011751.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 474442 phoR 7157456 phoR Escherichia coli UMN026 phosphate regulon sensor protein YP_002411200.1 473147 D 585056 CDS YP_002411201.1 218703682 7157461 474849..476168 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter; branched chain amino acid transporter (LIV-II) 476168 brnQ 7157461 brnQ Escherichia coli UMN026 branched chain amino acid transporter (LIV-II) YP_002411201.1 474849 D 585056 CDS YP_002411202.1 218703683 7155891 476244..477617 1 NC_011751.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 477617 proY 7155891 proY Escherichia coli UMN026 putative proline-specific permease YP_002411202.1 476244 D 585056 CDS YP_002411203.1 218703684 7157539 477773..479590 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme; maltodextrin glucosidase 479590 malZ 7157539 malZ Escherichia coli UMN026 maltodextrin glucosidase YP_002411203.1 477773 D 585056 CDS YP_002411204.1 218703685 7157053 479701..481248 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 481248 7157053 ECUMN_0441 Escherichia coli UMN026 hypothetical protein YP_002411204.1 479701 D 585056 CDS YP_002411205.1 218703686 7154675 complement(481269..481850) 1 NC_011751.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 481850 acpH 7154675 acpH Escherichia coli UMN026 acyl carrier protein phosphodiesterase YP_002411205.1 481269 R 585056 CDS YP_002411206.1 218703687 7155683 482069..483139 1 NC_011751.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 483139 queA 7155683 queA Escherichia coli UMN026 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002411206.1 482069 D 585056 CDS YP_002411207.1 218703688 7157612 483195..484322 1 NC_011751.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA -ribosyltransferase 484322 tgt 7157612 tgt Escherichia coli UMN026 queuine tRNA -ribosyltransferase YP_002411207.1 483195 D 585056 CDS YP_002411208.1 218703689 7158051 484345..484677 1 NC_011751.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 484677 yajC 7158051 yajC Escherichia coli UMN026 preprotein translocase subunit YajC YP_002411208.1 484345 D 585056 CDS YP_002411209.1 218703690 7158341 484705..486552 1 NC_011751.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 486552 secD 7158341 secD Escherichia coli UMN026 preprotein translocase subunit SecD YP_002411209.1 484705 D 585056 CDS YP_002411210.1 218703691 7157887 486563..487534 1 NC_011751.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 487534 secF 7157887 secF Escherichia coli UMN026 preprotein translocase subunit SecF YP_002411210.1 486563 D 585056 CDS YP_002411211.1 218703692 7157889 487663..488010 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 488010 yajD 7157889 yajD Escherichia coli UMN026 hypothetical protein YP_002411211.1 487663 D 585056 CDS YP_002411212.1 218703693 7158342 complement(488048..488932) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component; nucleoside channel phage T6/colicin K receptor 488932 tsx 7158342 tsx Escherichia coli UMN026 nucleoside channel phage T6/colicin K receptor YP_002411212.1 488048 R 585056 CDS YP_002411213.1 218703694 7158135 complement(489231..489770) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 489770 yajI 7158135 yajI Escherichia coli UMN026 hypothetical protein YP_002411213.1 489231 R 585056 CDS YP_002411214.1 218703695 7158344 489921..490370 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator NrdR 490370 nrdR 7158344 nrdR Escherichia coli UMN026 transcriptional regulator NrdR YP_002411214.1 489921 D 585056 CDS YP_002411215.1 218703696 7157306 490374..491477 1 NC_011751.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 491477 ribD 7157306 ribD Escherichia coli UMN026 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_002411215.1 490374 D 585056 CDS YP_002411216.1 218703697 7157685 491566..492036 1 NC_011751.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 492036 ribH 7157685 ribH Escherichia coli UMN026 6,7-dimethyl-8-ribityllumazine synthase YP_002411216.1 491566 D 585056 CDS YP_002411217.1 218703698 7157686 492056..492475 1 NC_011751.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 492475 nusB 7157686 nusB Escherichia coli UMN026 transcription antitermination protein NusB YP_002411217.1 492056 D 585056 CDS YP_002411218.1 218703699 7157339 492553..493530 1 NC_011751.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 493530 thiL 7157339 thiL Escherichia coli UMN026 thiamine monophosphate kinase YP_002411218.1 492553 D 585056 CDS YP_002411219.1 218703700 7158059 493508..494023 1 NC_011751.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 494023 pgpA 7158059 pgpA Escherichia coli UMN026 phosphatidylglycerophosphatase A YP_002411219.1 493508 D 585056 CDS YP_002411220.1 218703701 7157430 complement(494200..495771) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 495771 7157430 ECUMN_0457 Escherichia coli UMN026 hypothetical protein YP_002411220.1 494200 R 585056 CDS YP_002411221.1 218703702 7154676 complement(496002..496976) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme; aldoketo-oxidoreductase 496976 yajO 7154676 yajO Escherichia coli UMN026 aldoketo-oxidoreductase YP_002411221.1 496002 R 585056 CDS YP_002411222.1 218703703 7158346 complement(497031..498893) 1 NC_011751.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 498893 dxs 7158346 dxs Escherichia coli UMN026 1-deoxy-D-xylulose-5-phosphate synthase YP_002411222.1 497031 R 585056 CDS YP_002411223.1 218703704 7156216 complement(498918..499817) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme; geranyltranstransferase 499817 ispA 7156216 ispA Escherichia coli UMN026 geranyltranstransferase YP_002411223.1 498918 R 585056 CDS YP_002411224.1 218703705 7156862 complement(499817..500059) 1 NC_011751.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 500059 xseB 7156862 xseB Escherichia coli UMN026 exodeoxyribonuclease VII small subunit YP_002411224.1 499817 R 585056 CDS YP_002411225.1 218703706 7158250 500265..501713 1 NC_011751.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 501713 thiI 7158250 thiI Escherichia coli UMN026 thiamine biosynthesis protein ThiI YP_002411225.1 500265 D 585056 CDS YP_002411226.1 218703707 7158058 complement(501767..502357) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269; DJ-1 family protein 502357 yajL 7158058 yajL Escherichia coli UMN026 DJ-1 family protein YP_002411226.1 501767 R 585056 CDS YP_002411227.1 218703708 7158345 complement(502320..503231) 1 NC_011751.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 503231 panE 7158345 panE Escherichia coli UMN026 2-dehydropantoate 2-reductase YP_002411227.1 502320 R 585056 CDS YP_002411228.1 218703709 7157380 503399..503890 1 NC_011751.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 503890 yajQ 7157380 yajQ Escherichia coli UMN026 putative nucleotide-binding protein YP_002411228.1 503399 D 585056 CDS YP_002411229.1 218703710 7158347 complement(504018..505382) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter, major facilitator family 505382 yajR 7158347 yajR Escherichia coli UMN026 putative transporter, major facilitator family YP_002411229.1 504018 R 585056 CDS YP_002411230.1 218703711 7158348 complement(505531..506421) 1 NC_011751.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 506421 cyoE 7158348 cyoE Escherichia coli UMN026 protoheme IX farnesyltransferase YP_002411230.1 505531 R 585056 CDS YP_002411231.1 218703712 7156077 complement(506433..506762) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier; cytochrome o ubiquinol oxidase subunit IV 506762 cyoD 7156077 cyoD Escherichia coli UMN026 cytochrome o ubiquinol oxidase subunit IV YP_002411231.1 506433 R 585056 CDS YP_002411232.1 218703713 7156076 complement(506762..507376) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit III 507376 cyoC 7156076 cyoC Escherichia coli UMN026 cytochrome o ubiquinol oxidase subunit III YP_002411232.1 506762 R 585056 CDS YP_002411233.1 218703714 7156075 complement(507366..509357) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit I 509357 cyoB 7156075 cyoB Escherichia coli UMN026 cytochrome o ubiquinol oxidase subunit I YP_002411233.1 507366 R 585056 CDS YP_002411234.1 218703715 7156074 complement(509379..510326) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier; cytochrome o ubiquinol oxidase subunit II 510326 cyoA 7156074 cyoA Escherichia coli UMN026 cytochrome o ubiquinol oxidase subunit II YP_002411234.1 509379 R 585056 CDS YP_002411235.1 218703716 7156073 complement(510786..512261) 1 NC_011751.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 512261 ampG 7156073 ampG Escherichia coli UMN026 muropeptide transporter YP_002411235.1 510786 R 585056 CDS YP_002411236.1 218703717 7155740 complement(512305..512883) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 512883 yajG 7155740 yajG Escherichia coli UMN026 hypothetical protein YP_002411236.1 512305 R 585056 CDS YP_002411237.1 218703718 7158343 513188..513505 1 NC_011751.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 513505 bolA 7158343 bolA Escherichia coli UMN026 transcriptional regulator BolA YP_002411237.1 513188 D 585056 CDS YP_002411238.1 218703719 7155889 513439..513702 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 513702 7155889 ECUMN_0475 Escherichia coli UMN026 hypothetical protein YP_002411238.1 513439 D 585056 CDS YP_002411239.1 218703720 7154677 513849..515147 1 NC_011751.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 515147 tig 7154677 tig Escherichia coli UMN026 trigger factor YP_002411239.1 513849 D 585056 CDS YP_002411240.1 218703721 7158071 515393..516016 1 NC_011751.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 516016 clpP 7158071 clpP Escherichia coli UMN026 ATP-dependent Clp protease proteolytic subunit YP_002411240.1 515393 D 585056 CDS YP_002411241.1 218703722 7155980 516142..517416 1 NC_011751.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 517416 clpX 7155980 clpX Escherichia coli UMN026 ATP-dependent protease ATP-binding subunit ClpX YP_002411241.1 516142 D 585056 CDS YP_002411242.1 218703723 7157969 517604..519958 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme; DNA-binding ATP-dependent protease La 519958 lon 7157969 lon Escherichia coli UMN026 DNA-binding ATP-dependent protease La YP_002411242.1 517604 D 585056 CDS YP_002411243.1 218703724 7156999 520167..520439 1 NC_011751.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 520439 hupB 7156999 hupB Escherichia coli UMN026 transcriptional regulator HU subunit beta YP_002411243.1 520167 D 585056 CDS YP_002411244.1 218703725 7156733 520631..522502 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase 522502 ppiD 7156733 ppiD Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase YP_002411244.1 520631 D 585056 CDS YP_002411245.1 218703726 7157508 522653..523024 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 523024 ybaV 7157508 ybaV Escherichia coli UMN026 hypothetical protein YP_002411245.1 522653 D 585056 CDS YP_002411246.1 218703727 7158361 523118..523516 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 523516 ybaW 7158361 ybaW Escherichia coli UMN026 hypothetical protein YP_002411246.1 523118 D 585056 CDS YP_002411247.1 218703728 7158362 complement(523568..524263) 1 NC_011751.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 524263 queC 7158362 queC Escherichia coli UMN026 queuosine biosynthesis protein QueC YP_002411247.1 523568 R 585056 CDS YP_002411248.1 218703729 7157613 complement(524328..526028) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 526028 ybaE 7157613 ybaE Escherichia coli UMN026 hypothetical protein YP_002411248.1 524328 R 585056 CDS YP_002411249.1 218703730 7158351 526128..526946 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; thiamin pyrimidine pyrophosphate hydrolase 526946 cof 7158351 cof Escherichia coli UMN026 thiamin pyrimidine pyrophosphate hydrolase YP_002411249.1 526128 D 585056 CDS YP_002411250.1 218703731 7155997 527099..527557 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7904973, 10850996; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 527557 ybaO 7155997 ybaO Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411250.1 527099 D 585056 CDS YP_002411251.1 218703732 7158357 527587..529359 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : putative transporter; putative multidrug transporter membrane/ATP-binding protein 529359 mdlA 7158357 mdlA Escherichia coli UMN026 putative multidrug transporter membrane/ATP-binding protein YP_002411251.1 527587 D 585056 CDS YP_002411252.1 218703733 7157070 529352..531133 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : putative transporter; putative multidrug transporter membrane/ATP-binding protein 531133 mdlB 7157070 mdlB Escherichia coli UMN026 putative multidrug transporter membrane/ATP-binding protein YP_002411252.1 529352 D 585056 CDS YP_002411253.1 218703734 7157071 531314..531652 1 NC_011751.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 531652 glnK 7157071 glnK Escherichia coli UMN026 nitrogen regulatory protein P-II 2 YP_002411253.1 531314 D 585056 CDS YP_002411254.1 218703735 7156554 531682..532968 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter; ammonium transporter 532968 amtB 7156554 amtB Escherichia coli UMN026 ammonium transporter YP_002411254.1 531682 D 585056 CDS YP_002411255.1 218703736 7155742 complement(533017..533877) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme; acyl-CoA thioesterase II 533877 tesB 7155742 tesB Escherichia coli UMN026 acyl-CoA thioesterase II YP_002411255.1 533017 R 585056 CDS YP_002411256.1 218703737 7158048 534095..534667 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein 534667 ybaY 7158048 ybaY Escherichia coli UMN026 putative lipoprotein YP_002411256.1 534095 D 585056 CDS YP_002411257.1 218703738 7158363 complement(534698..535087) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methylated DNA-protein cysteine alkyltransferase 535087 ybaZ 7158363 ybaZ Escherichia coli UMN026 putative methylated DNA-protein cysteine alkyltransferase YP_002411257.1 534698 R 585056 CDS YP_002411258.1 218703739 7156341 535388..535741 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 535741 ybaA 7156341 ybaA Escherichia coli UMN026 hypothetical protein YP_002411258.1 535388 D 585056 CDS YP_002411259.1 218703740 7158349 complement(535783..537333) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 537333 ylaB 7158349 ylaB Escherichia coli UMN026 hypothetical protein YP_002411259.1 535783 R 585056 CDS YP_002411260.1 218703741 7159458 complement(537497..537967) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 537967 ylaC 7159458 ylaC Escherichia coli UMN026 hypothetical protein YP_002411260.1 537497 R 585056 CDS YP_002411261.1 218703742 7159459 complement(538083..538634) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82180540, 91310703, 9600841; Product type e : enzyme; maltose O-acetyltransferase 538634 maa 7159459 maa Escherichia coli UMN026 maltose O-acetyltransferase YP_002411261.1 538083 R 585056 CDS YP_002411262.1 218703743 7157036 complement(538806..539024) 1 NC_011751.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 539024 hha 7157036 hha Escherichia coli UMN026 hemolysin expression-modulating protein YP_002411262.1 538806 R 585056 CDS YP_002411263.1 218703744 7156669 complement(539050..539424) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275; hypothetical protein 539424 ybaJ 7156669 ybaJ Escherichia coli UMN026 hypothetical protein YP_002411263.1 539050 R 585056 CDS YP_002411264.1 218703745 7158352 complement(539970..543119) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system protein 543119 acrB 7158352 acrB Escherichia coli UMN026 multidrug efflux system protein YP_002411264.1 539970 R 585056 CDS YP_002411265.1 218703746 7155688 complement(543142..544335) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system 544335 acrA 7155688 acrA Escherichia coli UMN026 multidrug efflux system YP_002411265.1 543142 R 585056 CDS YP_002411266.1 218703747 7155687 544477..545124 1 NC_011751.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 545124 acrR 7155687 acrR Escherichia coli UMN026 DNA-binding transcriptional repressor AcrR YP_002411266.1 544477 D 585056 CDS YP_002411267.1 218703748 7155692 545252..548614 1 NC_011751.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 548614 kefA 7155692 kefA Escherichia coli UMN026 potassium efflux protein KefA YP_002411267.1 545252 D 585056 CDS YP_002411268.1 218703749 7156902 complement(548653..548817) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 548817 ybaM 7156902 ybaM Escherichia coli UMN026 hypothetical protein YP_002411268.1 548653 R 585056 CDS YP_002411269.1 218703750 7158355 complement(548831..549358) 1 NC_011751.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 549358 priC 7158355 priC Escherichia coli UMN026 primosomal replication protein N'' YP_002411269.1 548831 R 585056 CDS YP_002411270.1 218703751 7157524 549428..549805 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 549805 ybaN 7157524 ybaN Escherichia coli UMN026 hypothetical protein YP_002411270.1 549428 D 585056 CDS YP_002411271.1 218703752 7158356 549958..550509 1 NC_011751.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 550509 apt 7158356 apt Escherichia coli UMN026 adenine phosphoribosyltransferase YP_002411271.1 549958 D 585056 CDS YP_002411272.1 218703753 7155755 550638..552569 1 NC_011751.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 552569 dnaX 7155755 dnaX Escherichia coli UMN026 DNA polymerase III subunits gamma and tau YP_002411272.1 550638 D 585056 CDS YP_002411273.1 218703754 7156193 552622..552951 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903; hypothetical protein 552951 ybaB 7156193 ybaB Escherichia coli UMN026 hypothetical protein YP_002411273.1 552622 D 585056 CDS YP_002411274.1 218703755 7158350 552951..553556 1 NC_011751.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 553556 recR 7158350 recR Escherichia coli UMN026 recombination protein RecR YP_002411274.1 552951 D 585056 CDS YP_002411275.1 218703756 7157647 553666..555540 1 NC_011751.1 molecular chaperone; heat shock protein 90 555540 htpG 7157647 htpG Escherichia coli UMN026 heat shock protein 90 YP_002411275.1 553666 D 585056 CDS YP_002411276.1 218703757 7156726 555721..556365 1 NC_011751.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 556365 adk 7156726 adk Escherichia coli UMN026 adenylate kinase YP_002411276.1 555721 D 585056 CDS YP_002411277.1 218703758 7155703 556497..557459 1 NC_011751.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 557459 hemH 7155703 hemH Escherichia coli UMN026 ferrochelatase YP_002411277.1 556497 D 585056 CDS YP_002411278.1 218703759 7156657 complement(557456..558415) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme; acetyl esterase 558415 aes 7156657 aes Escherichia coli UMN026 acetyl esterase YP_002411278.1 557456 R 585056 CDS YP_002411279.1 218703760 7155707 558567..559871 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme; inosine/guanosine kinase 559871 gsk 7155707 gsk Escherichia coli UMN026 inosine/guanosine kinase YP_002411279.1 558567 D 585056 CDS YP_002411280.1 218703761 7156619 complement(560001..561677) 1 NC_011751.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein 561677 ybaL 7156619 ybaL Escherichia coli UMN026 putative cation:proton antiport protein YP_002411280.1 560001 R 585056 CDS YP_002411281.1 218703762 7158354 complement(561915..563135) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter; fosmidomycin efflux system, member of the major facilitator superfamily 563135 fsr 7158354 fsr Escherichia coli UMN026 fosmidomycin efflux system, member of the major facilitator superfamily YP_002411281.1 561915 R 585056 CDS YP_002411282.1 218703763 7156454 563353..565005 1 NC_011751.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 565005 ushA 7156454 ushA Escherichia coli UMN026 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_002411282.1 563353 D 585056 CDS YP_002411283.1 218703764 7157835 complement(565042..565521) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 565521 ybaK 7157835 ybaK Escherichia coli UMN026 hypothetical protein YP_002411283.1 565042 R 585056 CDS YP_002411284.1 218703765 7158353 complement(565537..565812) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 565812 7158353 ECUMN_0521 Escherichia coli UMN026 hypothetical protein YP_002411284.1 565537 R 585056 CDS YP_002411285.1 218703766 7157980 complement(565725..566519) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 566519 ybaP 7157980 ybaP Escherichia coli UMN026 hypothetical protein YP_002411285.1 565725 R 585056 CDS YP_002411286.1 218703767 7158358 complement(566691..569195) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter; copper exporting ATPase 569195 copA 7158358 copA Escherichia coli UMN026 copper exporting ATPase YP_002411286.1 566691 R 585056 CDS YP_002411287.1 218703768 7155998 569458..570390 1 NC_011751.1 catalyzes the formation of glutamate from glutamine; glutaminase 570390 ybaS 7155998 ybaS Escherichia coli UMN026 glutaminase YP_002411287.1 569458 D 585056 CDS YP_002411288.1 218703769 7158359 570393..571685 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative nitrogen-containing metabolite transporter 571685 ybaT 7158359 ybaT Escherichia coli UMN026 putative nitrogen-containing metabolite transporter YP_002411288.1 570393 D 585056 CDS YP_002411289.1 218703770 7158360 572023..573378 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane transport protein, type I secretion 573378 siiCA 7158360 siiCA Escherichia coli UMN026 outer membrane transport protein, type I secretion YP_002411289.1 572023 D 585056 CDS YP_002411290.1 218703771 7157926 573487..594264 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type f : factor; adhesin for cattle intestine colonization 594264 siiEA 7157926 siiEA Escherichia coli UMN026 adhesin for cattle intestine colonization YP_002411290.1 573487 D 585056 CDS YP_002411291.1 218703772 7157928 594268..596430 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein, ATP binding protein, protein export 596430 siiBA 7157928 siiBA Escherichia coli UMN026 type I secretion membrane protein, ATP binding protein, protein export YP_002411291.1 594268 D 585056 CDS YP_002411292.1 218703773 7157925 596427..597602 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; RtxD/HlyD/CyaD protein of type I secretion system 597602 siiDA 7157925 siiDA Escherichia coli UMN026 RtxD/HlyD/CyaD protein of type I secretion system YP_002411292.1 596427 D 585056 CDS YP_002411293.1 218703774 7157927 597599..598006 1 NC_011751.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 598006 cueR 7157927 cueR Escherichia coli UMN026 DNA-binding transcriptional regulator CueR YP_002411293.1 597599 D 585056 CDS YP_002411294.1 218703775 7156049 complement(598010..598213) 1 NC_011751.1 hypothetical protein 598213 7156049 ECUMN_0531 Escherichia coli UMN026 hypothetical protein YP_002411294.1 598010 R 585056 CDS YP_002411295.1 218703776 7154679 complement(598210..598632) 1 NC_011751.1 hypothetical protein 598632 7154679 ECUMN_0532 Escherichia coli UMN026 hypothetical protein YP_002411295.1 598210 R 585056 CDS YP_002411296.1 218703777 7154680 complement(598686..600488) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative adhesin/invasin-like protein 600488 7154680 ECUMN_0533 Escherichia coli UMN026 putative adhesin/invasin-like protein YP_002411296.1 598686 R 585056 CDS YP_002411297.1 218703778 7154681 600837..601199 1 NC_011751.1 hypothetical protein 601199 7154681 ECUMN_0534 Escherichia coli UMN026 hypothetical protein YP_002411297.1 600837 D 585056 CDS YP_002411298.1 218703779 7154682 complement(601384..601839) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 601839 ybbJ 7154682 ybbJ Escherichia coli UMN026 hypothetical protein YP_002411298.1 601384 R 585056 CDS YP_002411299.1 218703780 7158367 complement(601839..602756) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative protease, membrane anchored 602756 ybbK 7158367 ybbK Escherichia coli UMN026 putative protease, membrane anchored YP_002411299.1 601839 R 585056 CDS YP_002411300.1 218703781 7158368 602902..603579 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YbbL 603579 ybbL 7158368 ybbL Escherichia coli UMN026 putative ABC transporter ATP-binding protein YbbL YP_002411300.1 602902 D 585056 CDS YP_002411301.1 218703782 7158369 603566..604345 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative ABC transporter permease 604345 ybbM 7158369 ybbM Escherichia coli UMN026 putative ABC transporter permease YP_002411301.1 603566 D 585056 CDS YP_002411302.1 218703783 7158370 complement(604408..605262) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative thioredoxin domain-containing protein 605262 ybbN 7158370 ybbN Escherichia coli UMN026 putative thioredoxin domain-containing protein YP_002411302.1 604408 R 585056 CDS YP_002411303.1 218703784 7158371 complement(605323..606132) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; short chain dehydrogenase 606132 ybbO 7158371 ybbO Escherichia coli UMN026 short chain dehydrogenase YP_002411303.1 605323 R 585056 CDS YP_002411304.1 218703785 7158372 complement(606122..606748) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 606748 tesA 7158372 tesA Escherichia coli UMN026 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_002411304.1 606122 R 585056 CDS YP_002411305.1 218703786 7158047 606716..607402 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YbbA 607402 ybbA 7158047 ybbA Escherichia coli UMN026 putative ABC transporter ATP-binding protein YbbA YP_002411305.1 606716 D 585056 CDS YP_002411306.1 218703787 7158365 607399..609813 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; putative ABC transporter permease 609813 ybbP 7158365 ybbP Escherichia coli UMN026 putative ABC transporter permease YP_002411306.1 607399 D 585056 CDS YP_002411307.1 218703788 7158373 complement(610418..611512) 1 NC_011751.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 611512 ybbB 7158373 ybbB Escherichia coli UMN026 tRNA 2-selenouridine synthase YP_002411307.1 610418 R 585056 CDS YP_002411308.1 218703789 7158366 complement(611581..612507) 1 NC_011751.1 activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS 612507 ybbS 7158366 ybbS Escherichia coli UMN026 DNA-binding transcriptional activator AllS YP_002411308.1 611581 R 585056 CDS YP_002411309.1 218703790 7158374 612737..613219 1 NC_011751.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 613219 allA 7158374 allA Escherichia coli UMN026 ureidoglycolate hydrolase YP_002411309.1 612737 D 585056 CDS YP_002411310.1 218703791 7155726 613297..614112 1 NC_011751.1 regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 614112 allR 7155726 allR Escherichia coli UMN026 DNA-binding transcriptional repressor AllR YP_002411310.1 613297 D 585056 CDS YP_002411311.1 218703792 7155730 614202..615983 1 NC_011751.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 615983 gcl 7155730 gcl Escherichia coli UMN026 glyoxylate carboligase YP_002411311.1 614202 D 585056 CDS YP_002411312.1 218703793 7156518 615996..616772 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20029625, 8440684; Product type e : enzyme; hydroxypyruvate isomerase 616772 hyi 7156518 hyi Escherichia coli UMN026 hydroxypyruvate isomerase YP_002411312.1 615996 D 585056 CDS YP_002411313.1 218703794 7156769 616872..617750 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme; tartronate semialdehyde reductase, NADH-dependent 617750 glxR 7156769 glxR Escherichia coli UMN026 tartronate semialdehyde reductase, NADH-dependent YP_002411313.1 616872 D 585056 CDS YP_002411314.1 218703795 7156584 617920..619374 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1293888; Product type t : transporter; allantoin permease 619374 ybbW 7156584 ybbW Escherichia coli UMN026 allantoin permease YP_002411314.1 617920 D 585056 CDS YP_002411315.1 218703796 7158375 619434..620795 1 NC_011751.1 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 620795 allB 7158375 allB Escherichia coli UMN026 allantoinase YP_002411315.1 619434 D 585056 CDS YP_002411316.1 218703797 7155727 620852..622153 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative purine permease YbbY 622153 ybbY 7155727 ybbY Escherichia coli UMN026 putative purine permease YbbY YP_002411316.1 620852 D 585056 CDS YP_002411317.1 218703798 7158376 622175..623320 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme; glycerate kinase II 623320 glxK 7158376 glxK Escherichia coli UMN026 glycerate kinase II YP_002411317.1 622175 D 585056 CDS YP_002411318.1 218703799 7156583 complement(623450..624235) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 624235 ylbA 7156583 ylbA Escherichia coli UMN026 hypothetical protein YP_002411318.1 623450 R 585056 CDS YP_002411319.1 218703800 7159460 complement(624246..625481) 1 NC_011751.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 625481 allC 7159460 allC Escherichia coli UMN026 allantoate amidohydrolase YP_002411319.1 624246 R 585056 CDS YP_002411320.1 218703801 7155728 complement(625503..626552) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12460564, 20069628, 69151449; Product type e : enzyme; ureidoglycolate dehydrogenase 626552 allD 7155728 allD Escherichia coli UMN026 ureidoglycolate dehydrogenase YP_002411320.1 625503 R 585056 CDS YP_002411321.1 218703802 7155729 626869..628536 1 NC_011751.1 multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 628536 fdrA 7155729 fdrA Escherichia coli UMN026 membrane protein FdrA YP_002411321.1 626869 D 585056 CDS YP_002411322.1 218703803 7156322 628546..629805 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 629805 ylbE 7156322 ylbE Escherichia coli UMN026 hypothetical protein YP_002411322.1 628546 D 585056 CDS YP_002411323.1 218703804 7159461 629816..630631 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 630631 ylbF 7159461 ylbF Escherichia coli UMN026 hypothetical protein YP_002411323.1 629816 D 585056 CDS YP_002411324.1 218703805 7159462 630628..631521 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : putative enzyme; carbamate kinase 631521 ybcF 7159462 ybcF Escherichia coli UMN026 carbamate kinase YP_002411324.1 630628 D 585056 CDS YP_002411325.1 218703806 7158377 complement(631648..632715) 1 NC_011751.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 632715 purK 7158377 purK Escherichia coli UMN026 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002411325.1 631648 R 585056 CDS YP_002411326.1 218703807 7157579 complement(632712..633221) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase 633221 purE 7157579 purE Escherichia coli UMN026 N5-carboxyaminoimidazole ribonucleotide mutase YP_002411326.1 632712 R 585056 CDS YP_002411327.1 218703808 7157576 complement(633339..634061) 1 NC_011751.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 634061 lpxH 7157576 lpxH Escherichia coli UMN026 UDP-2,3-diacylglucosamine hydrolase YP_002411327.1 633339 R 585056 CDS YP_002411328.1 218703809 7157013 complement(634064..634558) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase B 634558 ppiB 7157013 ppiB Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase B YP_002411328.1 634064 R 585056 CDS YP_002411329.1 218703810 7157506 634732..636117 1 NC_011751.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 636117 cysS 7157506 cysS Escherichia coli UMN026 cysteinyl-tRNA synthetase YP_002411329.1 634732 D 585056 CDS YP_002411330.1 218703811 7156092 complement(636153..636674) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 636674 ybcI 7156092 ybcI Escherichia coli UMN026 hypothetical protein YP_002411330.1 636153 R 585056 CDS YP_002411331.1 218703812 7158379 complement(636782..636994) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : putative regulator; hypothetical protein 636994 ybcJ 7158379 ybcJ Escherichia coli UMN026 hypothetical protein YP_002411331.1 636782 R 585056 CDS YP_002411332.1 218703813 7158380 complement(636996..637862) 1 NC_011751.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 637862 folD 7158380 folD Escherichia coli UMN026 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002411332.1 636996 R 585056 CDS YP_002411333.1 218703814 7156426 638333..638875 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2890624; Product type ps : putative structure; putative fimbrial-like adhesin protein 638875 sfmA 7156426 sfmA Escherichia coli UMN026 putative fimbrial-like adhesin protein YP_002411333.1 638333 D 585056 CDS YP_002411334.1 218703815 7157904 639095..639787 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15372038, 2553674; Product type f : factor; pilin chaperone, periplasmic 639787 sfmC 7157904 sfmC Escherichia coli UMN026 pilin chaperone, periplasmic YP_002411334.1 639095 D 585056 CDS YP_002411335.1 218703816 7157905 639818..642427 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1970114; Product type pf : putative factor; putative outer membrane export usher protein 642427 sfmD 7157905 sfmD Escherichia coli UMN026 putative outer membrane export usher protein YP_002411335.1 639818 D 585056 CDS YP_002411336.1 218703817 7157906 642470..643447 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin protein 643447 sfmH 7157906 sfmH Escherichia coli UMN026 putative fimbrial-like adhesin protein YP_002411336.1 642470 D 585056 CDS YP_002411337.1 218703818 7157908 643458..643973 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2890624; Product type ps : putative structure; putative fimbrial protein 643973 sfmF 7157908 sfmF Escherichia coli UMN026 putative fimbrial protein YP_002411337.1 643458 D 585056 CDS YP_002411338.1 218703819 7157907 complement(643976..644608) 1 NC_011751.1 activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ 644608 fimZ 7157907 fimZ Escherichia coli UMN026 transcriptional regulator FimZ YP_002411338.1 643976 R 585056 CDS YP_002411339.1 218703820 7155631 complement(644943..646106) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90036709, 2183007; Product type pe : putative enzyme; putative integrase; DLP12 prophage 646106 intD 7155631 intD Escherichia coli UMN026 putative integrase; DLP12 prophage YP_002411339.1 644943 R 585056 CDS YP_002411340.1 218703821 7156844 complement(645962..646363) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Excisionase from phage origin 646363 7156844 ECUMN_0577 Escherichia coli UMN026 Excisionase from phage origin YP_002411340.1 645962 R 585056 CDS YP_002411341.1 218703822 7154683 complement(646305..646583) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 646583 7154683 ECUMN_0578 Escherichia coli UMN026 hypothetical protein YP_002411341.1 646305 R 585056 CDS YP_002411342.1 218703823 7154684 complement(646631..646849) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 646849 7154684 ECUMN_0579 Escherichia coli UMN026 hypothetical protein YP_002411342.1 646631 R 585056 CDS YP_002411343.1 218703824 7154685 complement(646942..647259) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 647259 7154685 ECUMN_0580 Escherichia coli UMN026 hypothetical protein YP_002411343.1 646942 R 585056 CDS YP_002411344.1 218703825 7154686 complement(647240..647431) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 647431 7154686 ECUMN_0581 Escherichia coli UMN026 hypothetical protein YP_002411344.1 647240 R 585056 CDS YP_002411345.1 218703826 7154687 complement(647583..648263) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin 648263 7154687 ECUMN_0582 Escherichia coli UMN026 exonuclease from phage origin YP_002411345.1 647583 R 585056 CDS YP_002411346.1 218703827 7154688 complement(648260..649045) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; recombination protein bet from phage origin 649045 7154688 ECUMN_0583 Escherichia coli UMN026 recombination protein bet from phage origin YP_002411346.1 648260 R 585056 CDS YP_002411347.1 218703828 7154689 complement(649051..649347) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative host-nuclease inhibitor protein Gam of bacteriophage 649347 7154689 ECUMN_0584 Escherichia coli UMN026 putative host-nuclease inhibitor protein Gam of bacteriophage YP_002411347.1 649051 R 585056 CDS YP_002411348.1 218703829 7154690 complement(649423..649629) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage Kil protein 649629 7154690 ECUMN_0585 Escherichia coli UMN026 prophage Kil protein YP_002411348.1 649423 R 585056 CDS YP_002411349.1 218703830 7154691 complement(650112..651044) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 651044 7154691 ECUMN_0586 Escherichia coli UMN026 hypothetical protein YP_002411349.1 650112 R 585056 CDS YP_002411350.1 218703831 7154692 complement(651041..651514) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 651514 7154692 ECUMN_0587 Escherichia coli UMN026 hypothetical protein YP_002411350.1 651041 R 585056 CDS YP_002411351.1 218703832 7154693 complement(651596..652351) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; regulatory protein CI from bacteriophage origin 652351 7154693 ECUMN_0588 Escherichia coli UMN026 regulatory protein CI from bacteriophage origin YP_002411351.1 651596 R 585056 CDS YP_002411352.1 218703833 7154694 652390..652620 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; hypothetical protein 652620 cro 7154694 cro Escherichia coli UMN026 hypothetical protein YP_002411352.1 652390 D 585056 CDS YP_002411353.1 218703834 7156015 652690..653229 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 612476; Product type h : extrachromosomal origin; regulatory protein CII from bacteriophage origin 653229 7156015 ECUMN_0590 Escherichia coli UMN026 regulatory protein CII from bacteriophage origin YP_002411353.1 652690 D 585056 CDS YP_002411354.1 218703835 7154695 653226..654245 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995831; Product type h : extrachromosomal origin; replication protein O frm phage origin 654245 7154695 ECUMN_0591 Escherichia coli UMN026 replication protein O frm phage origin YP_002411354.1 653226 D 585056 CDS YP_002411355.1 218703836 7154696 654242..654943 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative replication protein P of bacteriophage 654943 7154696 ECUMN_0592 Escherichia coli UMN026 putative replication protein P of bacteriophage YP_002411355.1 654242 D 585056 CDS YP_002411356.1 218703837 7154697 654940..655242 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; ren protein from phage origin 655242 7154697 ECUMN_0593 Escherichia coli UMN026 ren protein from phage origin YP_002411356.1 654940 D 585056 CDS YP_002411357.1 218703838 7154698 655173..655382 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 655382 7154698 ECUMN_0594 Escherichia coli UMN026 hypothetical protein YP_002411357.1 655173 D 585056 CDS YP_002411358.1 218703839 7154699 complement(655491..656993) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Chromosome segregation ATPase from phage origin, putative coiled-coil 656993 7154699 ECUMN_0595 Escherichia coli UMN026 Chromosome segregation ATPase from phage origin, putative coiled-coil YP_002411358.1 655491 R 585056 CDS YP_002411359.1 218703840 7154700 657369..657542 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 657542 7154700 ECUMN_0596 Escherichia coli UMN026 hypothetical protein YP_002411359.1 657369 D 585056 CDS YP_002411360.1 218703841 7154701 657806..658414 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 658414 7154701 ECUMN_0597 Escherichia coli UMN026 hypothetical protein YP_002411360.1 657806 D 585056 CDS YP_002411361.1 218703842 7154702 658650..659159 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 659159 7154702 ECUMN_0598 Escherichia coli UMN026 hypothetical protein YP_002411361.1 658650 D 585056 CDS YP_002411362.1 218703843 7154703 659354..659809 1 NC_011751.1 DLP12 prophage; hypothetical protein 659809 ybcN 7154703 ybcN Escherichia coli UMN026 hypothetical protein YP_002411362.1 659354 D 585056 CDS YP_002411363.1 218703844 7158381 659809..659979 1 NC_011751.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 659979 ninE 7158381 ninE Escherichia coli UMN026 prophage protein NinE YP_002411363.1 659809 D 585056 CDS YP_002411364.1 218703845 7157281 659972..660262 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 660262 ybcO 7157281 ybcO Escherichia coli UMN026 hypothetical protein YP_002411364.1 659972 D 585056 CDS YP_002411365.1 218703846 7158382 660259..660621 1 NC_011751.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 660621 rusA 7158382 rusA Escherichia coli UMN026 endodeoxyribonuclease RUS YP_002411365.1 660259 D 585056 CDS YP_002411366.1 218703847 7157819 660844..661227 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : putative factor; putative antitermination protein Q-like protein; DLP12 prophage 661227 ybcQ 7157819 ybcQ Escherichia coli UMN026 putative antitermination protein Q-like protein; DLP12 prophage YP_002411366.1 660844 D 585056 CDS YP_002411367.1 218703848 7158383 complement(661417..662499) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative outer membrane porin 662499 nmpC 7158383 nmpC Escherichia coli UMN026 putative outer membrane porin YP_002411367.1 661417 R 585056 CDS YP_002411368.1 218703849 7157291 663073..663288 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 663288 essD 7157291 essD Escherichia coli UMN026 putative phage lysis protein S; DLP12 prophage YP_002411368.1 663073 D 585056 CDS YP_002411369.1 218703850 7156269 663288..663785 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : putative enzyme; putative lysozyme; DLP12 prophage 663785 ybcS 7156269 ybcS Escherichia coli UMN026 putative lysozyme; DLP12 prophage YP_002411369.1 663288 D 585056 CDS YP_002411370.1 218703851 7158385 663770..664249 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Endopeptidase from phage origin 664249 Rz 7158385 Rz Escherichia coli UMN026 Endopeptidase from phage origin YP_002411370.1 663770 D 585056 CDS YP_002411371.1 218703852 7157860 complement(664531..664695) 1 NC_011751.1 Evidence 7 : Gene remnant; Product type h : extrachromosomal origin; Arginyl-tRNA synthetase 664695 7157860 ECUMN_0608 Escherichia coli UMN026 Arginyl-tRNA synthetase YP_002411371.1 664531 R 585056 CDS YP_002411372.1 218703853 7154704 complement(664741..665166) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 665166 7154704 ECUMN_0609 Escherichia coli UMN026 hypothetical protein YP_002411372.1 664741 R 585056 CDS YP_002411373.1 218703854 7154705 complement(665209..665442) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 665442 ynfO 7154705 ynfO Escherichia coli UMN026 hypothetical protein YP_002411373.1 665209 R 585056 CDS YP_002411374.1 218703855 7159528 665548..665691 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 665691 7159528 ECUMN_0611 Escherichia coli UMN026 hypothetical protein YP_002411374.1 665548 D 585056 CDS YP_002411375.1 218703856 7154706 665831..666376 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92334985; Product type h : extrachromosomal origin; DNA packaging protein; DLP12 prophage 666376 nohB 7154706 nohB Escherichia coli UMN026 DNA packaging protein; DLP12 prophage YP_002411375.1 665831 D 585056 CDS YP_002411376.1 218703857 7157292 666351..668276 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; terminase large subunit 668276 7157292 ECUMN_0613 Escherichia coli UMN026 terminase large subunit YP_002411376.1 666351 D 585056 CDS YP_002411377.1 218703858 7154707 668273..668479 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11302702; Product type h : extrachromosomal origin; Head-to-tail joining protein W (gpW) from bacteriophage origin 668479 W 7154707 W Escherichia coli UMN026 Head-to-tail joining protein W (gpW) from bacteriophage origin YP_002411377.1 668273 D 585056 CDS YP_002411378.1 218703859 7158213 668476..670077 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; portal protein B (Minor capsid protein B) from bacteriophage origin 670077 B 7158213 B Escherichia coli UMN026 portal protein B (Minor capsid protein B) from bacteriophage origin YP_002411378.1 668476 D 585056 CDS YP_002411379.1 218703860 7155846 669944..671389 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; Minor capsid protein C from bacteriophage origin 671389 C 7155846 C Escherichia coli UMN026 Minor capsid protein C from bacteriophage origin YP_002411379.1 669944 D 585056 CDS YP_002411380.1 218703861 7155900 671399..671731 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6233140; Product type h : extrachromosomal origin; head decoration protein (Major capsid protein D) from bacteriophage origin 671731 D 7155900 D Escherichia coli UMN026 head decoration protein (Major capsid protein D) from bacteriophage origin YP_002411380.1 671399 D 585056 CDS YP_002411381.1 218703862 7156097 671787..672812 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; major head protein (Major coat protein) from bacteriophage origin 672812 7156097 ECUMN_0618 Escherichia coli UMN026 major head protein (Major coat protein) from bacteriophage origin YP_002411381.1 671787 D 585056 CDS YP_002411382.1 218703863 7154708 672854..673249 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6279661; Product type h : extrachromosomal origin; DNA packaging protein FI from bacteriophage origin 673249 fI 7154708 fI Escherichia coli UMN026 DNA packaging protein FI from bacteriophage origin YP_002411382.1 672854 D 585056 CDS YP_002411383.1 218703864 7156350 673261..673614 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6221115; Product type h : extrachromosomal origin; Tail attachment protein (Minor capsid protein FII) from bacteriophage origin 673614 fII 7156350 fII Escherichia coli UMN026 Tail attachment protein (Minor capsid protein FII) from bacteriophage origin YP_002411383.1 673261 D 585056 CDS YP_002411384.1 218703865 7156354 673626..674204 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 674204 7156354 ECUMN_0621 Escherichia coli UMN026 Minor tail protein Z (GpZ) YP_002411384.1 673626 D 585056 CDS YP_002411385.1 218703866 7154709 674201..674596 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 674596 7154709 ECUMN_0622 Escherichia coli UMN026 Minor tail protein U YP_002411385.1 674201 D 585056 CDS YP_002411386.1 218703867 7154710 674574..675344 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 675344 7154710 ECUMN_0623 Escherichia coli UMN026 Major tail protein V YP_002411386.1 674574 D 585056 CDS YP_002411387.1 218703868 7154711 675360..675782 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 675782 7154711 ECUMN_0624 Escherichia coli UMN026 Minor tail protein G YP_002411387.1 675360 D 585056 CDS YP_002411388.1 218703869 7154712 675764..676198 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 676198 7154712 ECUMN_0625 Escherichia coli UMN026 Minor tail protein T YP_002411388.1 675764 D 585056 CDS YP_002411389.1 218703870 7154713 676191..678746 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 678746 7154713 ECUMN_0626 Escherichia coli UMN026 Minor tail protein H YP_002411389.1 676191 D 585056 CDS YP_002411390.1 218703871 7154714 678743..679072 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 679072 7154714 ECUMN_0627 Escherichia coli UMN026 Minor tail protein M YP_002411390.1 678743 D 585056 CDS YP_002411391.1 218703872 7154715 679072..679770 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 679770 7154715 ECUMN_0628 Escherichia coli UMN026 Minor tail protein L YP_002411391.1 679072 D 585056 CDS YP_002411392.1 218703873 7154716 679776..680519 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage 680519 7154716 ECUMN_0629 Escherichia coli UMN026 putative tail fiber component K of prophage YP_002411392.1 679776 D 585056 CDS YP_002411393.1 218703874 7154717 680417..681088 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 681088 7154717 ECUMN_0630 Escherichia coli UMN026 Tail assembly protein I YP_002411393.1 680417 D 585056 CDS YP_002411394.1 218703875 7154718 681148..684645 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 684645 7154718 ECUMN_0631 Escherichia coli UMN026 Host specificity protein J of prophage YP_002411394.1 681148 D 585056 CDS YP_002411395.1 218703876 7154719 684706..687075 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; putative side tail fiber protein from prophage 687075 7154719 ECUMN_0632 Escherichia coli UMN026 putative side tail fiber protein from prophage YP_002411395.1 684706 D 585056 CDS YP_002411396.1 218703877 7154720 687072..687353 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 687353 7154720 ECUMN_0633 Escherichia coli UMN026 hypothetical protein YP_002411396.1 687072 D 585056 CDS YP_002411397.1 218703878 7154721 687363..688067 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 688067 7154721 ECUMN_0634 Escherichia coli UMN026 hypothetical protein YP_002411397.1 687363 D 585056 CDS YP_002411398.1 218703879 7154722 688078..688371 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 688371 7154722 ECUMN_0635 Escherichia coli UMN026 hypothetical protein YP_002411398.1 688078 D 585056 CDS YP_002411399.1 218703880 7154723 689047..689796 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89155479, 94350824, 3295784, 2823063; Product type r : regulator; DNA-binding transcriptional activator; DLP12 prophage 689796 appY 7154723 appY Escherichia coli UMN026 DNA-binding transcriptional activator; DLP12 prophage YP_002411399.1 689047 D 585056 CDS YP_002411400.1 218703881 7155754 complement(690046..690999) 1 NC_011751.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 690999 ompT 7155754 ompT Escherichia coli UMN026 outer membrane protease YP_002411400.1 690046 R 585056 CDS YP_002411401.1 218703882 7157350 complement(691403..691519) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 691519 7157350 ECUMN_0638 Escherichia coli UMN026 hypothetical protein YP_002411401.1 691403 R 585056 CDS YP_002411402.1 218703883 7154724 complement(691513..692274) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6317653, 2536924; Product type r : regulator; DNA-binding transcriptional activator of porin biosynthesis 692274 envY 7154724 envY Escherichia coli UMN026 DNA-binding transcriptional activator of porin biosynthesis YP_002411402.1 691513 R 585056 CDS YP_002411403.1 218703884 7156256 complement(692457..693347) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 693347 ybcH 7156256 ybcH Escherichia coli UMN026 hypothetical protein YP_002411403.1 692457 R 585056 CDS YP_002411404.1 218703885 7158378 complement(693348..696320) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 receptor, outer membrane subunit 696320 nfrA 7158378 nfrA Escherichia coli UMN026 bacteriophage N4 receptor, outer membrane subunit YP_002411404.1 693348 R 585056 CDS YP_002411405.1 218703886 7157268 complement(696307..698544) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 adsorption protein B 698544 nfrB 7157268 nfrB Escherichia coli UMN026 bacteriophage N4 adsorption protein B YP_002411405.1 696307 R 585056 CDS YP_002411406.1 218703887 7157269 699092..699262 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 699262 7157269 ECUMN_0643 Escherichia coli UMN026 hypothetical protein YP_002411406.1 699092 D 585056 CDS YP_002411407.1 218703888 7154725 complement(699482..699910) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 699910 7154725 ECUMN_0644 Escherichia coli UMN026 hypothetical protein YP_002411407.1 699482 R 585056 CDS YP_002411408.1 218703889 7154726 complement(699938..700384) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 700384 7154726 ECUMN_0645 Escherichia coli UMN026 hypothetical protein YP_002411408.1 699938 R 585056 CDS YP_002411409.1 218703890 7154727 complement(700715..700957) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 700957 7154727 ECUMN_0646 Escherichia coli UMN026 hypothetical protein YP_002411409.1 700715 R 585056 CDS YP_002411410.1 218703891 7154728 complement(700991..701227) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 701227 7154728 ECUMN_0647 Escherichia coli UMN026 hypothetical protein YP_002411410.1 700991 R 585056 CDS YP_002411411.1 218703892 7154729 complement(701205..702341) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ph : phenotype; putative transposase 702341 yhhI 7154729 yhhI Escherichia coli UMN026 putative transposase YP_002411411.1 701205 R 585056 CDS YP_002411412.1 218703893 7159176 complement(702420..702689) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 702689 7159176 ECUMN_0649 Escherichia coli UMN026 hypothetical protein YP_002411412.1 702420 R 585056 CDS YP_002411413.1 218703894 7154730 complement(702707..703168) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 703168 7154730 ECUMN_0650 Escherichia coli UMN026 hypothetical protein YP_002411413.1 702707 R 585056 CDS YP_002411414.1 218703895 7154731 complement(703171..703371) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 703371 7154731 ECUMN_0651 Escherichia coli UMN026 hypothetical protein YP_002411414.1 703171 R 585056 CDS YP_002411415.1 218703896 7159178 complement(704732..705043) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 705043 7159178 ECUMN_0654 Escherichia coli UMN026 hypothetical protein YP_002411415.1 704732 R 585056 CDS YP_002411416.1 218703897 7154733 complement(705136..706146) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 706146 7154733 ECUMN_0655 Escherichia coli UMN026 hypothetical protein YP_002411416.1 705136 R 585056 CDS YP_002411417.1 218703898 7154734 complement(706178..706492) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 706492 7154734 ECUMN_0656 Escherichia coli UMN026 hypothetical protein YP_002411417.1 706178 R 585056 CDS YP_002411418.1 218703899 7154735 complement(706546..707586) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 707586 7154735 ECUMN_0657 Escherichia coli UMN026 hypothetical protein YP_002411418.1 706546 R 585056 CDS YP_002411419.1 218703900 7154736 complement(707698..708738) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 708738 7154736 ECUMN_0658 Escherichia coli UMN026 hypothetical protein YP_002411419.1 707698 R 585056 CDS YP_002411420.1 218703901 7154737 complement(708764..709063) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 709063 7154737 ECUMN_0659 Escherichia coli UMN026 hypothetical protein YP_002411420.1 708764 R 585056 CDS YP_002411421.1 218703902 7154738 complement(709432..710892) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator; sensor kinase CusS 710892 cusS 7154738 cusS Escherichia coli UMN026 sensor kinase CusS YP_002411421.1 709432 R 585056 CDS YP_002411422.1 218703903 7156055 complement(710870..711553) 1 NC_011751.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 711553 cusR 7156055 cusR Escherichia coli UMN026 DNA-binding transcriptional activator CusR YP_002411422.1 710870 R 585056 CDS YP_002411423.1 218703904 7156054 711704..713092 1 NC_011751.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 713092 cusC 7156054 cusC Escherichia coli UMN026 copper/silver efflux system outer membrane protein CusC YP_002411423.1 711704 D 585056 CDS YP_002411424.1 218703905 7156052 713116..713448 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor; periplasmic copper-binding protein 713448 cusF 7156052 cusF Escherichia coli UMN026 periplasmic copper-binding protein YP_002411424.1 713116 D 585056 CDS YP_002411425.1 218703906 7156053 713464..714687 1 NC_011751.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 714687 cusB 7156053 cusB Escherichia coli UMN026 copper/silver efflux system membrane fusion protein CusB YP_002411425.1 713464 D 585056 CDS YP_002411426.1 218703907 7156051 714699..717842 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter; copper/silver efflux system, membrane component 717842 cusA 7156051 cusA Escherichia coli UMN026 copper/silver efflux system, membrane component YP_002411426.1 714699 D 585056 CDS YP_002411427.1 218703908 7156050 717944..719320 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter; phenylalanine transporter 719320 pheP 7156050 pheP Escherichia coli UMN026 phenylalanine transporter YP_002411427.1 717944 D 585056 CDS YP_002411428.1 218703909 7157436 complement(719388..720635) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 720635 ybdG 7157436 ybdG Escherichia coli UMN026 hypothetical protein YP_002411428.1 719388 R 585056 CDS YP_002411429.1 218703910 7158394 complement(720743..721396) 1 NC_011751.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 721396 nfnB 7158394 nfnB Escherichia coli UMN026 dihydropteridine reductase YP_002411429.1 720743 R 585056 CDS YP_002411430.1 218703911 7157266 complement(721475..721978) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 721978 ybdF 7157266 ybdF Escherichia coli UMN026 hypothetical protein YP_002411430.1 721475 R 585056 CDS YP_002411431.1 218703912 7158393 complement(721923..722171) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 722171 ybdJ 7158393 ybdJ Escherichia coli UMN026 hypothetical protein YP_002411431.1 721923 R 585056 CDS YP_002411432.1 218703913 7158396 complement(722237..723355) 1 NC_011751.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 723355 ybdK 7158396 ybdK Escherichia coli UMN026 carboxylate-amine ligase YP_002411432.1 722237 R 585056 CDS YP_002411433.1 218703914 7158397 723367..723543 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 723543 7158397 ECUMN_0672 Escherichia coli UMN026 hypothetical protein YP_002411433.1 723367 D 585056 CDS YP_002411434.1 218703915 7154739 723773..723961 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor; toxic polypeptide, small 723961 hokE 7154739 hokE Escherichia coli UMN026 toxic polypeptide, small YP_002411434.1 723773 D 585056 CDS YP_002411435.1 218703916 7156694 724311..724463 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor; toxic polypeptide, small 724463 hokE 7156694 hokE Escherichia coli UMN026 toxic polypeptide, small YP_002411435.1 724311 D 585056 CDS YP_002411436.1 218703917 7156695 complement(724585..725355) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex 725355 entD 7156695 entD Escherichia coli UMN026 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_002411436.1 724585 R 585056 CDS YP_002411437.1 218703918 7156251 complement(725380..727620) 1 NC_011751.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 727620 fepA 7156251 fepA Escherichia coli UMN026 outer membrane receptor FepA YP_002411437.1 725380 R 585056 CDS YP_002411438.1 218703919 7156333 727941..729065 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme; enterobactin/ferric enterobactin esterase 729065 fes 7156333 fes Escherichia coli UMN026 enterobactin/ferric enterobactin esterase YP_002411438.1 727941 D 585056 CDS YP_002411439.1 218703920 7156339 729068..729286 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 729286 ybdZ 7156339 ybdZ Escherichia coli UMN026 hypothetical protein YP_002411439.1 729068 D 585056 CDS YP_002411440.1 218703921 7158400 729283..733164 1 NC_011751.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 733164 entF 7158400 entF Escherichia coli UMN026 enterobactin synthase subunit F YP_002411440.1 729283 D 585056 CDS YP_002411441.1 218703922 7156253 733260..734498 1 NC_011751.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 734498 fepE 7156253 fepE Escherichia coli UMN026 ferric enterobactin transport protein FepE YP_002411441.1 733260 D 585056 CDS YP_002411442.1 218703923 7156337 complement(734510..735325) 1 NC_011751.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 735325 fepC 7156337 fepC Escherichia coli UMN026 iron-enterobactin transporter ATP-binding protein YP_002411442.1 734510 R 585056 CDS YP_002411443.1 218703924 7156335 complement(735322..736314) 1 NC_011751.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 736314 fepG 7156335 fepG Escherichia coli UMN026 iron-enterobactin transporter permease YP_002411443.1 735322 R 585056 CDS YP_002411444.1 218703925 7156338 complement(736311..737315) 1 NC_011751.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 737315 fepD 7156338 fepD Escherichia coli UMN026 iron-enterobactin transporter membrane protein YP_002411444.1 736311 R 585056 CDS YP_002411445.1 218703926 7156336 737426..738676 1 NC_011751.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 738676 ybdA 7156336 ybdA Escherichia coli UMN026 enterobactin exporter EntS YP_002411445.1 737426 D 585056 CDS YP_002411446.1 218703927 7158390 complement(738680..739636) 1 NC_011751.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 739636 fepB 7158390 fepB Escherichia coli UMN026 iron-enterobactin transporter periplasmic binding protein YP_002411446.1 738680 R 585056 CDS YP_002411447.1 218703928 7156334 739825..741000 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme; isochorismate synthase 1 741000 entC 7156334 entC Escherichia coli UMN026 isochorismate synthase 1 YP_002411447.1 739825 D 585056 CDS YP_002411448.1 218703929 7156250 741010..742620 1 NC_011751.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 742620 entE 7156250 entE Escherichia coli UMN026 enterobactin synthase subunit E YP_002411448.1 741010 D 585056 CDS YP_002411449.1 218703930 7156252 742634..743491 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme; isochorismatase 743491 entB 7156252 entB Escherichia coli UMN026 isochorismatase YP_002411449.1 742634 D 585056 CDS YP_002411450.1 218703931 7156249 743491..744237 1 NC_011751.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 744237 entA 7156249 entA Escherichia coli UMN026 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002411450.1 743491 D 585056 CDS YP_002411451.1 218703932 7156248 744240..744653 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : putative enzyme; hypothetical protein 744653 ybdB 7156248 ybdB Escherichia coli UMN026 hypothetical protein YP_002411451.1 744240 D 585056 CDS YP_002411452.1 218703933 7158391 744834..746939 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91162636, 2521622; Product type pf : putative factor; carbon starvation protein 746939 cstA 7158391 cstA Escherichia coli UMN026 carbon starvation protein YP_002411452.1 744834 D 585056 CDS YP_002411453.1 218703934 7156047 747093..747290 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 747290 ybdD 7156047 ybdD Escherichia coli UMN026 hypothetical protein YP_002411453.1 747093 D 585056 CDS YP_002411454.1 218703935 7158392 complement(747300..748388) 1 NC_011751.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 748388 ybdH 7158392 ybdH Escherichia coli UMN026 hypothetical protein YP_002411454.1 747300 R 585056 CDS YP_002411455.1 218703936 7158395 748496..749656 1 NC_011751.1 catalyzes the transfer of an amino moiety; putative aminotransferase 749656 ybdL 7158395 ybdL Escherichia coli UMN026 putative aminotransferase YP_002411455.1 748496 D 585056 CDS YP_002411456.1 218703937 7158398 complement(749657..750286) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 750286 ibrB 7158398 ibrB Escherichia coli UMN026 immunoglobulin-binding regulator YP_002411456.1 749657 R 585056 CDS YP_002411457.1 218703938 7156783 complement(750259..751479) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 751479 ibrA 7156783 ibrA Escherichia coli UMN026 immunoglobulin-binding regulator YP_002411457.1 750259 R 585056 CDS YP_002411458.1 218703939 7156782 complement(751626..752564) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 752564 ybdO 7156782 ybdO Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411458.1 751626 R 585056 CDS YP_002411459.1 218703940 7158399 complement(752736..753482) 1 NC_011751.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 753482 dsbG 7158399 dsbG Escherichia coli UMN026 disulfide isomerase/thiol-disulfide oxidase YP_002411459.1 752736 R 585056 CDS YP_002411460.1 218703941 7156205 753854..754417 1 NC_011751.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 754417 ahpC 7156205 ahpC Escherichia coli UMN026 alkyl hydroperoxide reductase subunit C YP_002411460.1 753854 D 585056 CDS YP_002411461.1 218703942 7155717 754588..756153 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme; alkyl hydroperoxide reductase, F52a subunit 756153 ahpF 7155717 ahpF Escherichia coli UMN026 alkyl hydroperoxide reductase, F52a subunit YP_002411461.1 754588 D 585056 CDS YP_002411462.1 218703943 7155718 complement(756274..756702) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor; universal stress protein UP12 756702 uspG 7155718 uspG Escherichia coli UMN026 universal stress protein UP12 YP_002411462.1 756274 R 585056 CDS YP_002411463.1 218703944 7158196 complement(757058..757468) 1 NC_011751.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 757468 rnk 7158196 rnk Escherichia coli UMN026 nucleoside diphosphate kinase regulator YP_002411463.1 757058 R 585056 CDS YP_002411464.1 218703945 7157715 complement(757698..758504) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme; ribonuclease I 758504 rna 7157715 rna Escherichia coli UMN026 ribonuclease I YP_002411464.1 757698 R 585056 CDS YP_002411465.1 218703946 7157705 complement(758618..760081) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9696764; Product type t : transporter; citrate:succinate antiporter 760081 citT 7157705 citT Escherichia coli UMN026 citrate:succinate antiporter YP_002411465.1 758618 R 585056 CDS YP_002411466.1 218703947 7155973 complement(760131..761009) 1 NC_011751.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase 761009 citG 7155973 citG Escherichia coli UMN026 triphosphoribosyl-dephospho-CoA synthase YP_002411466.1 760131 R 585056 CDS YP_002411467.1 218703948 7155972 complement(760984..761535) 1 NC_011751.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase 761535 citX 7155972 citX Escherichia coli UMN026 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase YP_002411467.1 760984 R 585056 CDS YP_002411468.1 218703949 7155974 complement(761539..763071) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase, citrate-ACP transferase subunit alpha 763071 citF 7155974 citF Escherichia coli UMN026 citrate lyase, citrate-ACP transferase subunit alpha YP_002411468.1 761539 R 585056 CDS YP_002411469.1 218703950 7155971 complement(763082..763990) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase, citryl-ACP lyase subunit beta 763990 citE 7155971 citE Escherichia coli UMN026 citrate lyase, citryl-ACP lyase subunit beta YP_002411469.1 763082 R 585056 CDS YP_002411470.1 218703951 7155970 complement(763987..764283) 1 NC_011751.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 764283 citD 7155970 citD Escherichia coli UMN026 citrate lyase subunit gamma YP_002411470.1 763987 R 585056 CDS YP_002411471.1 218703952 7155969 complement(764298..765356) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme; citrate lyase synthetase 765356 citC 7155969 citC Escherichia coli UMN026 citrate lyase synthetase YP_002411471.1 764298 R 585056 CDS YP_002411472.1 218703953 7155968 765736..767394 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11889485, 21885746, 9701802; Product type r : regulator; sensory histidine kinase in two-component regulatory system with citB 767394 citA 7155968 citA Escherichia coli UMN026 sensory histidine kinase in two-component regulatory system with citB YP_002411472.1 765736 D 585056 CDS YP_002411473.1 218703954 7155966 767363..768043 1 NC_011751.1 regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 768043 dpiA 7155966 dpiA Escherichia coli UMN026 two-component response regulator DpiA YP_002411473.1 767363 D 585056 CDS YP_002411474.1 218703955 7155967 complement(768084..769469) 1 NC_011751.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 769469 dcuC 7155967 dcuC Escherichia coli UMN026 C4-dicarboxylate transporter DcuC YP_002411474.1 768084 R 585056 CDS YP_002411475.1 218703956 7156120 770058..770618 1 NC_011751.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 770618 pagP 7156120 pagP Escherichia coli UMN026 palmitoyl transferase YP_002411475.1 770058 D 585056 CDS YP_002411476.1 218703957 7156008 770793..771002 1 NC_011751.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 771002 cspE 7156008 cspE Escherichia coli UMN026 cold shock protein CspE YP_002411476.1 770793 D 585056 CDS YP_002411477.1 218703958 7156038 complement(771056..771439) 1 NC_011751.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 771439 crcB 7156038 crcB Escherichia coli UMN026 camphor resistance protein CrcB YP_002411477.1 771056 R 585056 CDS YP_002411478.1 218703959 7156009 771757..772320 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidase 772320 ybeM 7156009 ybeM Escherichia coli UMN026 putative amidase YP_002411478.1 771757 D 585056 CDS YP_002411479.1 218703960 7158406 772449..772652 1 NC_011751.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 772652 tatE 7158406 tatE Escherichia coli UMN026 twin arginine translocase protein E YP_002411479.1 772449 D 585056 CDS YP_002411480.1 218703961 7158029 complement(772753..773718) 1 NC_011751.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 773718 lipA 7158029 lipA Escherichia coli UMN026 lipoyl synthase YP_002411480.1 772753 R 585056 CDS YP_002411481.1 218703962 7156982 complement(773927..774880) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12218038; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 774880 ybeF 7156982 ybeF Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411481.1 773927 R 585056 CDS YP_002411482.1 218703963 7158404 774939..775088 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 775088 7158404 ECUMN_0722 Escherichia coli UMN026 hypothetical protein YP_002411482.1 774939 D 585056 CDS YP_002411483.1 218703964 7154740 complement(775140..775781) 1 NC_011751.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 775781 lipB 7154740 lipB Escherichia coli UMN026 lipoate-protein ligase B YP_002411483.1 775140 R 585056 CDS YP_002411484.1 218703965 7156983 complement(775882..776145) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795; hypothetical protein 776145 ybeD 7156983 ybeD Escherichia coli UMN026 hypothetical protein YP_002411484.1 775882 R 585056 CDS YP_002411485.1 218703966 7158403 complement(776255..777466) 1 NC_011751.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 777466 dacA 7158403 dacA Escherichia coli UMN026 D-alanyl-D-alanine carboxypeptidase fraction A YP_002411485.1 776255 R 585056 CDS YP_002411486.1 218703967 7156099 complement(777606..778694) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein; rare lipoprotein A 778694 rlpA 7156099 rlpA Escherichia coli UMN026 rare lipoprotein A YP_002411486.1 777606 R 585056 CDS YP_002411487.1 218703968 7157697 complement(778705..779817) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process; cell wall shape-determining protein 779817 mrdB 7157697 mrdB Escherichia coli UMN026 cell wall shape-determining protein YP_002411487.1 778705 R 585056 CDS YP_002411488.1 218703969 7157178 complement(779820..781721) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme; penicillin-binding protein 2 781721 mrdA 7157178 mrdA Escherichia coli UMN026 penicillin-binding protein 2 YP_002411488.1 779820 R 585056 CDS YP_002411489.1 218703970 7157177 complement(781752..782219) 1 NC_011751.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 782219 ybeA 7157177 ybeA Escherichia coli UMN026 rRNA large subunit methyltransferase YP_002411489.1 781752 R 585056 CDS YP_002411490.1 218703971 7158401 complement(782223..782540) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 782540 ybeB 7158401 ybeB Escherichia coli UMN026 hypothetical protein YP_002411490.1 782223 R 585056 CDS YP_002411491.1 218703972 7158402 complement(782800..783411) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7929373; Product type pe : putative enzyme; putative phosphatase with phosphoglycerate mutase domain 783411 phpB 7158402 phpB Escherichia coli UMN026 putative phosphatase with phosphoglycerate mutase domain YP_002411491.1 782800 R 585056 CDS YP_002411492.1 218703973 7157464 complement(783435..784076) 1 NC_011751.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 784076 nadD 7157464 nadD Escherichia coli UMN026 nicotinic acid mononucleotide adenylyltransferase YP_002411492.1 783435 R 585056 CDS YP_002411493.1 218703974 7157224 complement(784078..785109) 1 NC_011751.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 785109 holA 7157224 holA Escherichia coli UMN026 DNA polymerase III subunit delta YP_002411493.1 784078 R 585056 CDS YP_002411494.1 218703975 7156696 complement(785109..785690) 1 NC_011751.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 785690 rlpB 7156696 rlpB Escherichia coli UMN026 LPS-assembly lipoprotein RlpB YP_002411494.1 785109 R 585056 CDS YP_002411495.1 218703976 7157698 complement(785705..788287) 1 NC_011751.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 788287 leuS 7157698 leuS Escherichia coli UMN026 leucyl-tRNA synthetase YP_002411495.1 785705 R 585056 CDS YP_002411496.1 218703977 7156948 788522..789004 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469; hypothetical protein 789004 ybeL 7156948 ybeL Escherichia coli UMN026 hypothetical protein YP_002411496.1 788522 D 585056 CDS YP_002411497.1 218703978 7158405 complement(789075..790052) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 790052 ybeQ 7158405 ybeQ Escherichia coli UMN026 hypothetical protein YP_002411497.1 789075 R 585056 CDS YP_002411498.1 218703979 7158407 790216..790923 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 790923 ybeR 7158407 ybeR Escherichia coli UMN026 hypothetical protein YP_002411498.1 790216 D 585056 CDS YP_002411499.1 218703980 7158408 790920..792347 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12183460, 10574456; Product type pf : putative factor; putative DnaJ-class chaperone 792347 djlB 7158408 djlB Escherichia coli UMN026 putative DnaJ-class chaperone YP_002411499.1 790920 D 585056 CDS YP_002411500.1 218703981 7156173 complement(792357..792911) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 792911 ybeT 7156173 ybeT Escherichia coli UMN026 hypothetical protein YP_002411500.1 792357 R 585056 CDS YP_002411501.1 218703982 7158409 793013..793720 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 793720 ybeU 7158409 ybeU Escherichia coli UMN026 hypothetical protein YP_002411501.1 793013 D 585056 CDS YP_002411502.1 218703983 7158410 793717..795168 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 12054669; Product type f : factor; Hsc56 co-chaperone of HscC 795168 djlC 7158410 djlC Escherichia coli UMN026 Hsc56 co-chaperone of HscC YP_002411502.1 793717 D 585056 CDS YP_002411503.1 218703984 7156174 complement(795228..796898) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 14734171, 22055095, 9735342; Product type f : factor; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 796898 hscC 7156174 hscC Escherichia coli UMN026 Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription YP_002411503.1 795228 R 585056 CDS YP_002411504.1 218703985 7156716 complement(796982..797917) 1 NC_011751.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 797917 rihA 7156716 rihA Escherichia coli UMN026 ribonucleoside hydrolase 1 YP_002411504.1 796982 R 585056 CDS YP_002411505.1 218703986 7157688 complement(798035..798760) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter ATP-binding protein 798760 gltL 7157688 gltL Escherichia coli UMN026 glutamate and aspartate ABC transporter ATP-binding protein YP_002411505.1 798035 R 585056 CDS YP_002411506.1 218703987 7156579 complement(798760..799434) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 799434 gltK 7156579 gltK Escherichia coli UMN026 glutamate and aspartate ABC transporter membrane protein YP_002411506.1 798760 R 585056 CDS YP_002411507.1 218703988 7156578 complement(799434..800174) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 800174 gltJ 7156578 gltJ Escherichia coli UMN026 glutamate and aspartate ABC transporter membrane protein YP_002411507.1 799434 R 585056 CDS YP_002411508.1 218703989 7156577 complement(800344..801252) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter; glutamate and aspartate transporter subunit 801252 gltI 7156577 gltI Escherichia coli UMN026 glutamate and aspartate transporter subunit YP_002411508.1 800344 R 585056 CDS YP_002411509.1 218703990 7156576 complement(801649..803187) 1 NC_011751.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 803187 lnt 7156576 lnt Escherichia coli UMN026 apolipoprotein N-acyltransferase YP_002411509.1 801649 R 585056 CDS YP_002411510.1 218703991 7156993 complement(803212..804090) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : putative transporter; hypothetical protein 804090 ybeX 7156993 ybeX Escherichia coli UMN026 hypothetical protein YP_002411510.1 803212 R 585056 CDS YP_002411511.1 218703992 7158411 complement(804180..804647) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : putative enzyme; putative metalloprotease 804647 ybeY 7158411 ybeY Escherichia coli UMN026 putative metalloprotease YP_002411511.1 804180 R 585056 CDS YP_002411512.1 218703993 7158412 complement(804644..805723) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : putative enzyme; hypothetical protein 805723 ybeZ 7158412 ybeZ Escherichia coli UMN026 hypothetical protein YP_002411512.1 804644 R 585056 CDS YP_002411513.1 218703994 7158413 complement(805837..807261) 1 NC_011751.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 807261 miaB 7158413 miaB Escherichia coli UMN026 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002411513.1 805837 R 585056 CDS YP_002411514.1 218703995 7157129 807407..808582 1 NC_011751.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 808582 ubiF 7157129 ubiF Escherichia coli UMN026 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002411514.1 807407 D 585056 CDS YP_002411515.1 218703996 7155647 809269..809421 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 809421 7155647 ECUMN_0757 Escherichia coli UMN026 hypothetical protein YP_002411515.1 809269 D 585056 CDS YP_002411516.1 218703997 7155645 809774..810037 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 810037 7155645 ECUMN_0758 Escherichia coli UMN026 hypothetical protein YP_002411516.1 809774 D 585056 CDS YP_002411517.1 218703998 7154742 complement(810252..811916) 1 NC_011751.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 811916 asnB 7154742 asnB Escherichia coli UMN026 asparagine synthetase B YP_002411517.1 810252 R 585056 CDS YP_002411518.1 218703999 7155814 complement(812313..813065) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme; UMP phosphatase 813065 nagD 7155814 nagD Escherichia coli UMN026 UMP phosphatase YP_002411518.1 812313 R 585056 CDS YP_002411519.1 218704000 7157230 complement(813113..814333) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator; DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine 814333 nagC 7157230 nagC Escherichia coli UMN026 DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine YP_002411519.1 813113 R 585056 CDS YP_002411520.1 218704001 7157229 complement(814342..815490) 1 NC_011751.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 815490 nagA 7157229 nagA Escherichia coli UMN026 N-acetylglucosamine-6-phosphate deacetylase YP_002411520.1 814342 R 585056 CDS YP_002411521.1 218704002 7157227 complement(815550..816350) 1 NC_011751.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 816350 nagB 7157227 nagB Escherichia coli UMN026 glucosamine-6-phosphate deaminase YP_002411521.1 815550 R 585056 CDS YP_002411522.1 218704003 7157228 816683..818629 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 818629 nagE 7157228 nagE Escherichia coli UMN026 PTS system N-acetyl glucosamine specific transporter subunits IIABC YP_002411522.1 816683 D 585056 CDS YP_002411523.1 218704004 7157231 818832..820496 1 NC_011751.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 820496 glnS 7157231 glnS Escherichia coli UMN026 glutaminyl-tRNA synthetase YP_002411523.1 818832 D 585056 CDS YP_002411524.1 218704005 7156558 820944..822350 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : putative transporter; putative outer membrane porin 822350 ybfM 7156558 ybfM Escherichia coli UMN026 putative outer membrane porin YP_002411524.1 820944 D 585056 CDS YP_002411525.1 218704006 7158417 822400..822726 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 822726 ybfN 7158417 ybfN Escherichia coli UMN026 putative lipoprotein YP_002411525.1 822400 D 585056 CDS YP_002411526.1 218704007 7158418 complement(822811..823257) 1 NC_011751.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 823257 fur 7158418 fur Escherichia coli UMN026 ferric uptake regulator YP_002411526.1 822811 R 585056 CDS YP_002411527.1 218704008 7156479 823302..823556 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 823556 7156479 ECUMN_0769 Escherichia coli UMN026 hypothetical protein YP_002411527.1 823302 D 585056 CDS YP_002411528.1 218704009 7154743 complement(823546..824076) 1 NC_011751.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 824076 fldA 7154743 fldA Escherichia coli UMN026 flavodoxin FldA YP_002411528.1 823546 R 585056 CDS YP_002411529.1 218704010 7156375 complement(824216..824509) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process; LexA regulated protein 824509 ybfE 7156375 ybfE Escherichia coli UMN026 LexA regulated protein YP_002411529.1 824216 R 585056 CDS YP_002411530.1 218704011 7158415 complement(824649..825413) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; hypothetical protein 825413 ybfF 7158415 ybfF Escherichia coli UMN026 hypothetical protein YP_002411530.1 824649 R 585056 CDS YP_002411531.1 218704012 7158416 825598..826143 1 NC_011751.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 826143 seqA 7158416 seqA Escherichia coli UMN026 replication initiation regulator SeqA YP_002411531.1 825598 D 585056 CDS YP_002411532.1 218704013 7157896 826169..827809 1 NC_011751.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 827809 pgm 7157896 pgm Escherichia coli UMN026 phosphoglucomutase YP_002411532.1 826169 D 585056 CDS YP_002411533.1 218704014 7157429 828014..828508 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 828508 ybfP 7157429 ybfP Escherichia coli UMN026 hypothetical protein YP_002411533.1 828014 D 585056 CDS YP_002411534.1 218704015 7158419 complement(828620..829297) 1 NC_011751.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 829297 kdpE 7158419 kdpE Escherichia coli UMN026 DNA-binding transcriptional activator KdpE YP_002411534.1 828620 R 585056 CDS YP_002411535.1 218704016 7156894 complement(829294..831978) 1 NC_011751.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 831978 kdpD 7156894 kdpD Escherichia coli UMN026 sensor protein KdpD YP_002411535.1 829294 R 585056 CDS YP_002411536.1 218704017 7156893 complement(831971..832543) 1 NC_011751.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 832543 kdpC 7156893 kdpC Escherichia coli UMN026 potassium-transporting ATPase subunit C YP_002411536.1 831971 R 585056 CDS YP_002411537.1 218704018 7156892 complement(832552..834600) 1 NC_011751.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 834600 kdpB 7156892 kdpB Escherichia coli UMN026 potassium-transporting ATPase subunit B YP_002411537.1 832552 R 585056 CDS YP_002411538.1 218704019 7156891 complement(834623..836296) 1 NC_011751.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 836296 kdpA 7156891 kdpA Escherichia coli UMN026 potassium-transporting ATPase subunit A YP_002411538.1 834623 R 585056 CDS YP_002411539.1 218704020 7156890 836698..836904 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 836904 ybfA 7156890 ybfA Escherichia coli UMN026 hypothetical protein YP_002411539.1 836698 D 585056 CDS YP_002411540.1 218704021 7158414 837429..837782 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 837782 7158414 ECUMN_0782 Escherichia coli UMN026 hypothetical protein YP_002411540.1 837429 D 585056 CDS YP_002411541.1 218704022 7154744 837865..838149 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 838149 7154744 ECUMN_0783 Escherichia coli UMN026 hypothetical protein YP_002411541.1 837865 D 585056 CDS YP_002411542.1 218704023 7154745 838162..838569 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 838569 7154745 ECUMN_0784 Escherichia coli UMN026 hypothetical protein YP_002411542.1 838162 D 585056 CDS YP_002411543.1 218704024 7154746 838654..839163 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990; hypothetical protein 839163 ybgA 7154746 ybgA Escherichia coli UMN026 hypothetical protein YP_002411543.1 838654 D 585056 CDS YP_002411544.1 218704025 7158420 839160..840578 1 NC_011751.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 840578 phr 7158420 phr Escherichia coli UMN026 deoxyribodipyrimidine photolyase YP_002411544.1 839160 D 585056 CDS YP_002411545.1 218704026 7157465 complement(840620..842101) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : putative transporter; putative transporter 842101 ybgH 7157465 ybgH Escherichia coli UMN026 putative transporter YP_002411545.1 840620 R 585056 CDS YP_002411546.1 218704027 7158424 842372..843115 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207; putative hydrolase-oxidase 843115 ybgI 7158424 ybgI Escherichia coli UMN026 putative hydrolase-oxidase YP_002411546.1 842372 D 585056 CDS YP_002411547.1 218704028 7158425 843138..843794 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase subunit 843794 ybgJ 7158425 ybgJ Escherichia coli UMN026 putative hydrolase subunit YP_002411547.1 843138 D 585056 CDS YP_002411548.1 218704029 7158426 843788..844720 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase subunit 844720 ybgK 7158426 ybgK Escherichia coli UMN026 putative hydrolase subunit YP_002411548.1 843788 D 585056 CDS YP_002411549.1 218704030 7158427 844710..845444 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : putative enzyme; LamB/YcsF family protein 845444 ybgL 7158427 ybgL Escherichia coli UMN026 LamB/YcsF family protein YP_002411549.1 844710 D 585056 CDS YP_002411550.1 218704031 7158428 845480..846271 1 NC_011751.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 846271 nei 7158428 nei Escherichia coli UMN026 endonuclease VIII YP_002411550.1 845480 D 585056 CDS YP_002411551.1 218704032 7157263 complement(846268..847314) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype; hypothetical protein 847314 abrB 7157263 abrB Escherichia coli UMN026 hypothetical protein YP_002411551.1 846268 R 585056 CDS YP_002411552.1 218704033 7155670 complement(847466..848527) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 848527 ybgO 7155670 ybgO Escherichia coli UMN026 hypothetical protein YP_002411552.1 847466 R 585056 CDS YP_002411553.1 218704034 7158429 complement(848524..849255) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10049807; Product type pf : putative factor; putative exported chaperone, PapD family 849255 ybgP 7158429 ybgP Escherichia coli UMN026 putative exported chaperone, PapD family YP_002411553.1 848524 R 585056 CDS YP_002411554.1 218704035 7158430 complement(849271..851772) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 851772 ybgQ 7158430 ybgQ Escherichia coli UMN026 hypothetical protein YP_002411554.1 849271 R 585056 CDS YP_002411555.1 218704036 7158431 complement(851781..852434) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative fimbrial-like adhesin protein 852434 7158431 ECUMN_0797 Escherichia coli UMN026 putative fimbrial-like adhesin protein YP_002411555.1 851781 R 585056 CDS YP_002411556.1 218704037 7154747 complement(852737..854020) 1 NC_011751.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 854020 gltA 7154747 gltA Escherichia coli UMN026 type II citrate synthase YP_002411556.1 852737 R 585056 CDS YP_002411557.1 218704038 7156573 854729..855118 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component; succinate dehydrogenase cytochrome b556 large membrane subunit 855118 sdhC 7156573 sdhC Escherichia coli UMN026 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002411557.1 854729 D 585056 CDS YP_002411558.1 218704039 7157882 855112..855459 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component; succinate dehydrogenase cytochrome b556 small membrane subunit 855459 sdhD 7157882 sdhD Escherichia coli UMN026 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002411558.1 855112 D 585056 CDS YP_002411559.1 218704040 7157883 855459..857225 1 NC_011751.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 857225 sdhA 7157883 sdhA Escherichia coli UMN026 succinate dehydrogenase flavoprotein subunit YP_002411559.1 855459 D 585056 CDS YP_002411560.1 218704041 7157880 857241..857957 1 NC_011751.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 857957 sdhB 7157880 sdhB Escherichia coli UMN026 succinate dehydrogenase iron-sulfur subunit YP_002411560.1 857241 D 585056 CDS YP_002411561.1 218704042 7157881 858307..861108 1 NC_011751.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 861108 sucA 7157881 sucA Escherichia coli UMN026 2-oxoglutarate dehydrogenase E1 component YP_002411561.1 858307 D 585056 CDS YP_002411562.1 218704043 7157998 861123..862340 1 NC_011751.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 862340 sucB 7157998 sucB Escherichia coli UMN026 dihydrolipoamide succinyltransferase YP_002411562.1 861123 D 585056 CDS YP_002411563.1 218704044 7157999 862615..863781 1 NC_011751.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 863781 sucC 7157999 sucC Escherichia coli UMN026 succinyl-CoA synthetase subunit beta YP_002411563.1 862615 D 585056 CDS YP_002411564.1 218704045 7158000 863781..864650 1 NC_011751.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 864650 sucD 7158000 sucD Escherichia coli UMN026 succinyl-CoA synthetase subunit alpha YP_002411564.1 863781 D 585056 CDS YP_002411565.1 218704046 7157836 864695..865045 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 865045 7157836 ECUMN_0807 Escherichia coli UMN026 hypothetical protein YP_002411565.1 864695 D 585056 CDS YP_002411566.1 218704047 7154748 865316..866221 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-like transcriptional regulator 866221 7154748 ECUMN_0808 Escherichia coli UMN026 putative LysR-like transcriptional regulator YP_002411566.1 865316 D 585056 CDS YP_002411567.1 218704048 7154749 complement(866255..866857) 1 NC_011751.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 866857 7154749 ECUMN_0809 Escherichia coli UMN026 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002411567.1 866255 R 585056 CDS YP_002411568.1 218704049 7154750 complement(866867..868519) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Fumarate hydratase class I subunit beta 868519 7154750 ECUMN_0810 Escherichia coli UMN026 Fumarate hydratase class I subunit beta YP_002411568.1 866867 R 585056 CDS YP_002411569.1 218704050 7154751 complement(868627..869928) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative symport protein 869928 7154751 ECUMN_0811 Escherichia coli UMN026 putative symport protein YP_002411569.1 868627 R 585056 CDS YP_002411570.1 218704051 7154752 complement(870068..870385) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 870385 7154752 ECUMN_0812 Escherichia coli UMN026 hypothetical protein YP_002411570.1 870068 R 585056 CDS YP_002411571.1 218704052 7154753 complement(870382..871752) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11748244; Product type pe : putative enzyme; putative 3-methylaspartate ammonia-lyase, glutamate mutase 871752 7154753 ECUMN_0813 Escherichia coli UMN026 putative 3-methylaspartate ammonia-lyase, glutamate mutase YP_002411571.1 870382 R 585056 CDS YP_002411572.1 218704053 7154754 complement(871756..872997) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate ammonia-lyase 872997 7154754 ECUMN_0814 Escherichia coli UMN026 methylaspartate ammonia-lyase YP_002411572.1 871756 R 585056 CDS YP_002411573.1 218704054 7154755 complement(872997..874442) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate mutase E chain 874442 7154755 ECUMN_0815 Escherichia coli UMN026 methylaspartate mutase E chain YP_002411573.1 872997 R 585056 CDS YP_002411574.1 218704055 7154756 complement(874461..875849) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7880251; Product type e : enzyme; glutamate mutase, large subunit 875849 glmL 7154756 glmL Escherichia coli UMN026 glutamate mutase, large subunit YP_002411574.1 874461 R 585056 CDS YP_002411575.1 218704056 7156544 complement(875849..876361) 1 NC_011751.1 converts methylaspartate to L-glutamate; methylaspartate mutase subunit S 876361 7156544 ECUMN_0817 Escherichia coli UMN026 methylaspartate mutase subunit S YP_002411575.1 875849 R 585056 CDS YP_002411576.1 218704057 7154757 complement(876485..876652) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 876652 7154757 ECUMN_0818 Escherichia coli UMN026 hypothetical protein YP_002411576.1 876485 R 585056 CDS YP_002411577.1 218704058 7154758 complement(876846..877268) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 877268 7154758 ECUMN_0819 Escherichia coli UMN026 hypothetical protein YP_002411577.1 876846 R 585056 CDS YP_002411578.1 218704059 7154759 complement(877349..878293) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 878293 7154759 ECUMN_0820 Escherichia coli UMN026 hypothetical protein YP_002411578.1 877349 R 585056 CDS YP_002411579.1 218704060 7154760 879099..880667 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase, subunit I 880667 cydA 7154760 cydA Escherichia coli UMN026 cytochrome d terminal oxidase, subunit I YP_002411579.1 879099 D 585056 CDS YP_002411580.1 218704061 7156065 880683..881822 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase, subunit II 881822 cydB 7156065 cydB Escherichia coli UMN026 cytochrome d terminal oxidase, subunit II YP_002411580.1 880683 D 585056 CDS YP_002411581.1 218704062 7156066 881950..882243 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 882243 ybgE 7156066 ybgE Escherichia coli UMN026 hypothetical protein YP_002411581.1 881950 D 585056 CDS YP_002411582.1 218704063 7158422 882393..882797 1 NC_011751.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 882797 ybgC 7158422 ybgC Escherichia coli UMN026 acyl-CoA thioester hydrolase YbgC YP_002411582.1 882393 D 585056 CDS YP_002411583.1 218704064 7158421 882794..883486 1 NC_011751.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 883486 tolQ 7158421 tolQ Escherichia coli UMN026 colicin uptake protein TolQ YP_002411583.1 882794 D 585056 CDS YP_002411584.1 218704065 7158084 883490..883918 1 NC_011751.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 883918 tolR 7158084 tolR Escherichia coli UMN026 colicin uptake protein TolR YP_002411584.1 883490 D 585056 CDS YP_002411585.1 218704066 7158085 883983..885248 1 NC_011751.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 885248 tolA 7158085 tolA Escherichia coli UMN026 cell envelope integrity inner membrane protein TolA YP_002411585.1 883983 D 585056 CDS YP_002411586.1 218704067 7158081 885381..886673 1 NC_011751.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 886673 tolB 7158081 tolB Escherichia coli UMN026 translocation protein TolB YP_002411586.1 885381 D 585056 CDS YP_002411587.1 218704068 7158082 886708..887229 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein; peptidoglycan-associated outer membrane lipoprotein 887229 pal 7158082 pal Escherichia coli UMN026 peptidoglycan-associated outer membrane lipoprotein YP_002411587.1 886708 D 585056 CDS YP_002411588.1 218704069 7157376 887239..888030 1 NC_011751.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 888030 ybgF 7157376 ybgF Escherichia coli UMN026 tol-pal system protein YbgF YP_002411588.1 887239 D 585056 CDS YP_002411589.1 218704070 7155570 889686..890729 1 NC_011751.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 890729 nadA 7155570 nadA Escherichia coli UMN026 quinolinate synthetase YP_002411589.1 889686 D 585056 CDS YP_002411590.1 218704071 7157220 890767..891486 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter; nicotinamide mononucleotide transporter 891486 pnuC 7157220 pnuC Escherichia coli UMN026 nicotinamide mononucleotide transporter YP_002411590.1 890767 D 585056 CDS YP_002411591.1 218704072 7157483 complement(891483..892424) 1 NC_011751.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 892424 zitB 7157483 zitB Escherichia coli UMN026 zinc transporter ZitB YP_002411591.1 891483 R 585056 CDS YP_002411592.1 218704073 7159686 complement(892538..892918) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 892918 ybgS 7159686 ybgS Escherichia coli UMN026 hypothetical protein YP_002411592.1 892538 R 585056 CDS YP_002411593.1 218704074 7158432 893234..894286 1 NC_011751.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 894286 aroG 7158432 aroG Escherichia coli UMN026 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002411593.1 893234 D 585056 CDS YP_002411594.1 218704075 7155789 complement(894452..895204) 1 NC_011751.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 895204 gpmA 7155789 gpmA Escherichia coli UMN026 phosphoglyceromutase YP_002411594.1 894452 R 585056 CDS YP_002411595.1 218704076 7156604 complement(895407..896447) 1 NC_011751.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 896447 galM 7156604 galM Escherichia coli UMN026 aldose 1-epimerase YP_002411595.1 895407 R 585056 CDS YP_002411596.1 218704077 7156496 complement(896441..897589) 1 NC_011751.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 897589 galK 7156496 galK Escherichia coli UMN026 galactokinase YP_002411596.1 896441 R 585056 CDS YP_002411597.1 218704078 7156495 complement(897593..898639) 1 NC_011751.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 898639 galT 7156495 galT Escherichia coli UMN026 galactose-1-phosphate uridylyltransferase YP_002411597.1 897593 R 585056 CDS YP_002411598.1 218704079 7156500 complement(898649..899665) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme; UDP-galactose-4-epimerase 899665 galE 7156500 galE Escherichia coli UMN026 UDP-galactose-4-epimerase YP_002411598.1 898649 R 585056 CDS YP_002411599.1 218704080 7156493 complement(899928..901400) 1 NC_011751.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF 901400 modF 7156493 modF Escherichia coli UMN026 putative molybdenum transport ATP-binding protein ModF YP_002411599.1 899928 R 585056 CDS YP_002411600.1 218704081 7157157 complement(901328..901474) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 901474 7157157 ECUMN_0845 Escherichia coli UMN026 hypothetical protein YP_002411600.1 901328 R 585056 CDS YP_002411601.1 218704082 7154761 complement(901468..902256) 1 NC_011751.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 902256 modE 7154761 modE Escherichia coli UMN026 DNA-binding transcriptional regulator ModE YP_002411601.1 901468 R 585056 CDS YP_002411602.1 218704083 7157156 902385..902534 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 902534 ybhT 7157156 ybhT Escherichia coli UMN026 hypothetical protein YP_002411602.1 902385 D 585056 CDS YP_002411603.1 218704084 7158450 902701..903474 1 NC_011751.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 903474 modA 7158450 modA Escherichia coli UMN026 molybdate transporter periplasmic protein YP_002411603.1 902701 D 585056 CDS YP_002411604.1 218704085 7157152 903474..904163 1 NC_011751.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease protein 904163 modB 7157152 modB Escherichia coli UMN026 molybdate ABC transporter permease protein YP_002411604.1 903474 D 585056 CDS YP_002411605.1 218704086 7157153 904166..905224 1 NC_011751.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 905224 modC 7157153 modC Escherichia coli UMN026 molybdate transporter ATP-binding protein YP_002411605.1 904166 D 585056 CDS YP_002411606.1 218704087 7157154 complement(905225..906043) 1 NC_011751.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 906043 ybhA 7157154 ybhA Escherichia coli UMN026 phosphotransferase YP_002411606.1 905225 R 585056 CDS YP_002411607.1 218704088 7158433 906198..907193 1 NC_011751.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 907193 pgl 7158433 pgl Escherichia coli UMN026 6-phosphogluconolactonase YP_002411607.1 906198 D 585056 CDS YP_002411608.1 218704089 7157428 complement(907234..908250) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 908250 ybhD 7157428 ybhD Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411608.1 907234 R 585056 CDS YP_002411609.1 218704090 7158436 908371..909423 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 909423 ybhH 7158436 ybhH Escherichia coli UMN026 hypothetical protein YP_002411609.1 908371 D 585056 CDS YP_002411610.1 218704091 7158439 909499..910932 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative anion transporter 910932 ybhI 7158439 ybhI Escherichia coli UMN026 putative anion transporter YP_002411610.1 909499 D 585056 CDS YP_002411611.1 218704092 7158440 911115..913376 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11782506; Product type pe : putative enzyme; hypothetical protein 913376 ybhJ 7158440 ybhJ Escherichia coli UMN026 hypothetical protein YP_002411611.1 911115 D 585056 CDS YP_002411612.1 218704093 7158441 complement(913517..914800) 1 NC_011751.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase 914800 ybhC 7158441 ybhC Escherichia coli UMN026 putative pectinesterase YP_002411612.1 913517 R 585056 CDS YP_002411613.1 218704094 7158435 complement(914935..916005) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6446713; Product type h : extrachromosomal origin; Integrase from phage 916005 int 7158435 int Escherichia coli UMN026 Integrase from phage YP_002411613.1 914935 R 585056 CDS YP_002411614.1 218704095 7156838 complement(916316..916660) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 916660 yfdT 7156838 yfdT Escherichia coli UMN026 hypothetical protein YP_002411614.1 916316 R 585056 CDS YP_002411615.1 218704096 7158928 complement(916657..917535) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phosphoadenosine phosphosulfate reductase from phage origin 917535 7158928 ECUMN_0860 Escherichia coli UMN026 putative phosphoadenosine phosphosulfate reductase from phage origin YP_002411615.1 916657 R 585056 CDS YP_002411616.1 218704097 7154762 complement(917526..918062) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 918062 yfdR 7154762 yfdR Escherichia coli UMN026 hypothetical protein YP_002411616.1 917526 R 585056 CDS YP_002411617.1 218704098 7158927 complement(918190..919014) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 919014 yfdQ 7158927 yfdQ Escherichia coli UMN026 hypothetical protein YP_002411617.1 918190 R 585056 CDS YP_002411618.1 218704099 7158926 complement(919080..919442) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 919442 yfdP 7158926 yfdP Escherichia coli UMN026 hypothetical protein YP_002411618.1 919080 R 585056 CDS YP_002411619.1 218704100 7158925 919515..919739 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 919739 7158925 ECUMN_0864 Escherichia coli UMN026 hypothetical protein YP_002411619.1 919515 D 585056 CDS YP_002411620.1 218704101 7154763 919911..920345 1 NC_011751.1 Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 920345 7154763 ECUMN_0865 Escherichia coli UMN026 hypothetical protein YP_002411620.1 919911 D 585056 CDS YP_002411621.1 218704102 7154764 complement(920317..920538) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 920538 7154764 ECUMN_0866 Escherichia coli UMN026 hypothetical protein YP_002411621.1 920317 R 585056 CDS YP_002411622.1 218704103 7154765 complement(920871..921563) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative transcriptional regulator from phage origin 921563 7154765 ECUMN_0867 Escherichia coli UMN026 putative transcriptional regulator from phage origin YP_002411622.1 920871 R 585056 CDS YP_002411623.1 218704104 7154766 921661..921921 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative lambda repressor-like DNA-binding domain-containing protein 921921 7154766 ECUMN_0868 Escherichia coli UMN026 putative lambda repressor-like DNA-binding domain-containing protein YP_002411623.1 921661 D 585056 CDS YP_002411624.1 218704105 7154767 921914..922465 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative nucleic acid-binding protein; e14 prophage 922465 ymfL 7154767 ymfL Escherichia coli UMN026 putative nucleic acid-binding protein; e14 prophage YP_002411624.1 921914 D 585056 CDS YP_002411625.1 218704106 7159482 922462..922800 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 922800 ymfM 7159482 ymfM Escherichia coli UMN026 hypothetical protein YP_002411625.1 922462 D 585056 CDS YP_002411626.1 218704107 7159483 922810..923751 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage replication protein O 923751 7159483 ECUMN_0872 Escherichia coli UMN026 putative phage replication protein O YP_002411626.1 922810 D 585056 CDS YP_002411627.1 218704108 7154768 923748..924236 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 924236 yfdN 7154768 yfdN Escherichia coli UMN026 hypothetical protein YP_002411627.1 923748 D 585056 CDS YP_002411628.1 218704109 7158924 924203..924562 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 924562 7158924 ECUMN_0874 Escherichia coli UMN026 hypothetical protein YP_002411628.1 924203 D 585056 CDS YP_002411629.1 218704110 7154769 924559..924948 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 924948 rusA 7154769 rusA Escherichia coli UMN026 Crossover junction endodeoxyribonuclease YP_002411629.1 924559 D 585056 CDS YP_002411630.1 218704111 7157820 924866..925777 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 925777 7157820 ECUMN_0876 Escherichia coli UMN026 hypothetical protein YP_002411630.1 924866 D 585056 CDS YP_002411631.1 218704112 7154770 925779..926774 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 926774 7154770 ECUMN_0877 Escherichia coli UMN026 hypothetical protein YP_002411631.1 925779 D 585056 CDS YP_002411632.1 218704113 7154771 926792..927148 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; antitermination protein from phage origin 927148 Q 7154771 Q Escherichia coli UMN026 antitermination protein from phage origin YP_002411632.1 926792 D 585056 CDS YP_002411633.1 218704114 7157606 complement(927128..928342) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 928342 7157606 ECUMN_0879 Escherichia coli UMN026 hypothetical protein YP_002411633.1 927128 R 585056 CDS YP_002411634.1 218704115 7154772 complement(928345..929520) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 929520 7154772 ECUMN_0880 Escherichia coli UMN026 hypothetical protein YP_002411634.1 928345 R 585056 CDS YP_002411635.1 218704116 7154773 929542..929694 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 929694 7154773 ECUMN_0881 Escherichia coli UMN026 hypothetical protein YP_002411635.1 929542 D 585056 CDS YP_002411636.1 218704117 7154774 929812..930138 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2998005; Product type h : extrachromosomal origin; Holin 930138 S 7154774 S Escherichia coli UMN026 Holin YP_002411636.1 929812 D 585056 CDS YP_002411637.1 218704118 7157863 930142..930618 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysozyme inhibitor 930618 r 7157863 r Escherichia coli UMN026 lysozyme inhibitor YP_002411637.1 930142 D 585056 CDS YP_002411638.1 218704119 7157615 930602..930994 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Rz lytic protein from phage origin 930994 7157615 ECUMN_0884 Escherichia coli UMN026 putative Rz lytic protein from phage origin YP_002411638.1 930602 D 585056 CDS YP_002411639.1 218704120 7154775 930813..931136 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Rz1 lytic protein from bacteriophage origin 931136 7154775 ECUMN_0885 Escherichia coli UMN026 putative Rz1 lytic protein from bacteriophage origin YP_002411639.1 930813 D 585056 CDS YP_002411640.1 218704121 7154776 complement(931176..931481) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 931481 7154776 ECUMN_0886 Escherichia coli UMN026 hypothetical protein YP_002411640.1 931176 R 585056 CDS YP_002411641.1 218704122 7154777 931555..931905 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative endonuclease 931905 7154777 ECUMN_0887 Escherichia coli UMN026 putative endonuclease YP_002411641.1 931555 D 585056 CDS YP_002411642.1 218704123 7154778 932022..932525 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage terminase, small subunit 932525 7154778 ECUMN_0888 Escherichia coli UMN026 putative phage terminase, small subunit YP_002411642.1 932022 D 585056 CDS YP_002411643.1 218704124 7154779 932522..934255 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage terminase 934255 7154779 ECUMN_0889 Escherichia coli UMN026 putative phage terminase YP_002411643.1 932522 D 585056 CDS YP_002411644.1 218704125 7154780 934267..934449 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 934449 ymfR 7154780 ymfR Escherichia coli UMN026 hypothetical protein YP_002411644.1 934267 D 585056 CDS YP_002411645.1 218704126 7159485 934449..935690 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage portal protein 935690 7159485 ECUMN_0891 Escherichia coli UMN026 putative phage portal protein YP_002411645.1 934449 D 585056 CDS YP_002411646.1 218704127 7154781 935632..936318 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage pro-head protease 936318 7154781 ECUMN_0892 Escherichia coli UMN026 putative phage pro-head protease YP_002411646.1 935632 D 585056 CDS YP_002411647.1 218704128 7154782 936333..937538 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative major capsid protein 937538 7154782 ECUMN_0893 Escherichia coli UMN026 putative major capsid protein YP_002411647.1 936333 D 585056 CDS YP_002411648.1 218704129 7154783 937587..937787 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 937787 7154783 ECUMN_0894 Escherichia coli UMN026 hypothetical protein YP_002411648.1 937587 D 585056 CDS YP_002411649.1 218704130 7154784 937790..938113 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 938113 7154784 ECUMN_0895 Escherichia coli UMN026 hypothetical protein YP_002411649.1 937790 D 585056 CDS YP_002411650.1 218704131 7154785 938110..938520 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage head-tail adaptor 938520 7154785 ECUMN_0896 Escherichia coli UMN026 putative phage head-tail adaptor YP_002411650.1 938110 D 585056 CDS YP_002411651.1 218704132 7154786 938495..939001 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 939001 7154786 ECUMN_0897 Escherichia coli UMN026 hypothetical protein YP_002411651.1 938495 D 585056 CDS YP_002411652.1 218704133 7154787 938998..939558 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 939558 7154787 ECUMN_0898 Escherichia coli UMN026 hypothetical protein YP_002411652.1 938998 D 585056 CDS YP_002411653.1 218704134 7154788 939567..939737 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 939737 7154788 ECUMN_0899 Escherichia coli UMN026 hypothetical protein YP_002411653.1 939567 D 585056 CDS YP_002411654.1 218704135 7154789 939721..941217 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail sheath protein 941217 7154789 ECUMN_0900 Escherichia coli UMN026 Tail sheath protein YP_002411654.1 939721 D 585056 CDS YP_002411655.1 218704136 7154790 941217..941573 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage tail protein 941573 7154790 ECUMN_0901 Escherichia coli UMN026 putative phage tail protein YP_002411655.1 941217 D 585056 CDS YP_002411656.1 218704137 7154791 941570..941893 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 941893 7154791 ECUMN_0902 Escherichia coli UMN026 hypothetical protein YP_002411656.1 941570 D 585056 CDS YP_002411657.1 218704138 7154792 941978..943885 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative phage tail tape measure protein 943885 7154792 ECUMN_0903 Escherichia coli UMN026 putative phage tail tape measure protein YP_002411657.1 941978 D 585056 CDS YP_002411658.1 218704139 7154793 943910..945286 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail/DNA circulation protein 945286 7154793 ECUMN_0904 Escherichia coli UMN026 Tail/DNA circulation protein YP_002411658.1 943910 D 585056 CDS YP_002411659.1 218704140 7154794 945283..946362 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail protein 946362 7154794 ECUMN_0905 Escherichia coli UMN026 Tail protein YP_002411659.1 945283 D 585056 CDS YP_002411660.1 218704141 7154795 946362..946910 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative baseplate assembly phage protein 946910 7154795 ECUMN_0906 Escherichia coli UMN026 putative baseplate assembly phage protein YP_002411660.1 946362 D 585056 CDS YP_002411661.1 218704142 7154796 946907..947335 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail protein 947335 7154796 ECUMN_0907 Escherichia coli UMN026 putative tail protein YP_002411661.1 946907 D 585056 CDS YP_002411662.1 218704143 7154797 947322..948380 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative baseplate J-like phage protein 948380 7154797 ECUMN_0908 Escherichia coli UMN026 putative baseplate J-like phage protein YP_002411662.1 947322 D 585056 CDS YP_002411663.1 218704144 7154798 948371..948955 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 948955 ymfQ 7154798 ymfQ Escherichia coli UMN026 hypothetical protein YP_002411663.1 948371 D 585056 CDS YP_002411664.1 218704145 7159484 948959..949891 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; putative carbohydrate kinase; bacteriophage origin 949891 7159484 ECUMN_0910 Escherichia coli UMN026 putative carbohydrate kinase; bacteriophage origin YP_002411664.1 948959 D 585056 CDS YP_002411665.1 218704146 7154799 949892..950296 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 950296 7154799 ECUMN_0911 Escherichia coli UMN026 hypothetical protein YP_002411665.1 949892 D 585056 CDS YP_002411666.1 218704147 7154800 complement(950598..952085) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 952085 7154800 ECUMN_0912 Escherichia coli UMN026 hypothetical protein YP_002411666.1 950598 R 585056 CDS YP_002411667.1 218704148 7154801 complement(952072..953001) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage 953001 yfdH 7154801 yfdH Escherichia coli UMN026 bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage YP_002411667.1 952072 R 585056 CDS YP_002411668.1 218704149 7158923 complement(952998..953360) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage 953360 yfdG 7158923 yfdG Escherichia coli UMN026 bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage YP_002411668.1 952998 R 585056 CDS YP_002411669.1 218704150 7158922 complement(953809..954285) 1 NC_011751.1 YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein 954285 ybhB 7158922 ybhB Escherichia coli UMN026 putative kinase inhibitor protein YP_002411669.1 953809 R 585056 CDS YP_002411670.1 218704151 7158434 complement(954344..955633) 1 NC_011751.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase 955633 bioA 7158434 bioA Escherichia coli UMN026 adenosylmethionine--8-amino-7-oxononanoate transaminase YP_002411670.1 954344 R 585056 CDS YP_002411671.1 218704152 7155876 955720..956760 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme; biotin synthase 956760 bioB 7155876 bioB Escherichia coli UMN026 biotin synthase YP_002411671.1 955720 D 585056 CDS YP_002411672.1 218704153 7155877 956757..957911 1 NC_011751.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 957911 bioF 7155877 bioF Escherichia coli UMN026 8-amino-7-oxononanoate synthase YP_002411672.1 956757 D 585056 CDS YP_002411673.1 218704154 7155880 957898..958653 1 NC_011751.1 putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 958653 bioC 7155880 bioC Escherichia coli UMN026 biotin biosynthesis protein BioC YP_002411673.1 957898 D 585056 CDS YP_002411674.1 218704155 7155878 958646..959323 1 NC_011751.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 959323 bioD 7155878 bioD Escherichia coli UMN026 dithiobiotin synthetase YP_002411674.1 958646 D 585056 CDS YP_002411675.1 218704156 7155879 959902..961923 1 NC_011751.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 961923 uvrB 7155879 uvrB Escherichia coli UMN026 excinuclease ABC subunit B YP_002411675.1 959902 D 585056 CDS YP_002411676.1 218704157 7158199 complement(962070..962978) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : putative enzyme; putative transferase 962978 ybhK 7158199 ybhK Escherichia coli UMN026 putative transferase YP_002411676.1 962070 R 585056 CDS YP_002411677.1 218704158 7158442 complement(963221..963376) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 963376 7158442 ECUMN_0923 Escherichia coli UMN026 hypothetical protein YP_002411677.1 963221 R 585056 CDS YP_002411678.1 218704159 7154802 963375..964364 1 NC_011751.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 964364 moaA 7154802 moaA Escherichia coli UMN026 molybdenum cofactor biosynthesis protein A YP_002411678.1 963375 D 585056 CDS YP_002411679.1 218704160 7157145 964386..964898 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : putative factor; molybdopterin biosynthesis protein B 964898 moaB 7157145 moaB Escherichia coli UMN026 molybdopterin biosynthesis protein B YP_002411679.1 964386 D 585056 CDS YP_002411680.1 218704161 7157146 964901..965386 1 NC_011751.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 965386 moaC 7157146 moaC Escherichia coli UMN026 molybdenum cofactor biosynthesis protein MoaC YP_002411680.1 964901 D 585056 CDS YP_002411681.1 218704162 7157147 965379..965624 1 NC_011751.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 965624 moaD 7157147 moaD Escherichia coli UMN026 molybdopterin synthase small subunit YP_002411681.1 965379 D 585056 CDS YP_002411682.1 218704163 7157148 965626..966078 1 NC_011751.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 966078 moaE 7157148 moaE Escherichia coli UMN026 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_002411682.1 965626 D 585056 CDS YP_002411683.1 218704164 7157149 966215..966919 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 966919 ybhL 7157149 ybhL Escherichia coli UMN026 hypothetical protein YP_002411683.1 966215 D 585056 CDS YP_002411684.1 218704165 7158443 967124..967513 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 967513 7158443 ECUMN_0931 Escherichia coli UMN026 hypothetical protein YP_002411684.1 967124 D 585056 CDS YP_002411685.1 218704166 7154803 complement(967549..968505) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 968505 ybhN 7154803 ybhN Escherichia coli UMN026 hypothetical protein YP_002411685.1 967549 R 585056 CDS YP_002411686.1 218704167 7158444 complement(968505..969746) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme; cardiolipin synthase 2 969746 ybhO 7158444 ybhO Escherichia coli UMN026 cardiolipin synthase 2 YP_002411686.1 968505 R 585056 CDS YP_002411687.1 218704168 7158445 complement(969743..970504) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal-dependent hydrolase 970504 ybhP 7158445 ybhP Escherichia coli UMN026 putative metal-dependent hydrolase YP_002411687.1 969743 R 585056 CDS YP_002411688.1 218704169 7158446 970637..971047 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 971047 ybhQ 7158446 ybhQ Escherichia coli UMN026 hypothetical protein YP_002411688.1 970637 D 585056 CDS YP_002411689.1 218704170 7158447 complement(971009..972115) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease 972115 ybhR 7158447 ybhR Escherichia coli UMN026 putative ABC transporter permease YP_002411689.1 971009 R 585056 CDS YP_002411690.1 218704171 7158448 complement(972126..973259) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease 973259 ybhS 7158448 ybhS Escherichia coli UMN026 putative ABC transporter permease YP_002411690.1 972126 R 585056 CDS YP_002411691.1 218704172 7158449 complement(973252..974988) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 974988 ybhF 7158449 ybhF Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002411691.1 973252 R 585056 CDS YP_002411692.1 218704173 7158437 complement(974981..975979) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : putative transporter; hypothetical protein 975979 ybhG 7158437 ybhG Escherichia coli UMN026 hypothetical protein YP_002411692.1 974981 R 585056 CDS YP_002411693.1 218704174 7158438 complement(975979..976650) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 976650 ybiH 7158438 ybiH Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411693.1 975979 R 585056 CDS YP_002411694.1 218704175 7158454 976879..978243 1 NC_011751.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 978243 rhlE 7158454 rhlE Escherichia coli UMN026 ATP-dependent RNA helicase RhlE YP_002411694.1 976879 D 585056 CDS YP_002411695.1 218704176 7157676 complement(978479..978961) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 978961 ybiA 7157676 ybiA Escherichia coli UMN026 hypothetical protein YP_002411695.1 978479 R 585056 CDS YP_002411696.1 218704177 7158451 979081..981231 1 NC_011751.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 981231 dinG 7158451 dinG Escherichia coli UMN026 ATP-dependent DNA helicase DinG YP_002411696.1 979081 D 585056 CDS YP_002411697.1 218704178 7156169 981259..982221 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glycosyl transferase family protein 982221 ybiB 7156169 ybiB Escherichia coli UMN026 glycosyl transferase family protein YP_002411697.1 981259 D 585056 CDS YP_002411698.1 218704179 7158452 982362..983447 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : putative enzyme; hypothetical protein 983447 ybiC 7158452 ybiC Escherichia coli UMN026 hypothetical protein YP_002411698.1 982362 D 585056 CDS YP_002411699.1 218704180 7158453 complement(983676..983936) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 983936 ybiJ 7158453 ybiJ Escherichia coli UMN026 hypothetical protein YP_002411699.1 983676 R 585056 CDS YP_002411700.1 218704181 7158456 complement(984201..984467) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 984467 ybiI 7158456 ybiI Escherichia coli UMN026 hypothetical protein YP_002411700.1 984201 R 585056 CDS YP_002411701.1 218704182 7158455 complement(984541..985218) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative hydroxylase 985218 ybiX 7158455 ybiX Escherichia coli UMN026 putative hydroxylase YP_002411701.1 984541 R 585056 CDS YP_002411702.1 218704183 7158467 complement(985260..987542) 1 NC_011751.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 987542 fiu 7158467 fiu Escherichia coli UMN026 catecholate siderophore receptor Fiu YP_002411702.1 985260 R 585056 CDS YP_002411703.1 218704184 7156367 complement(987807..988211) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 988211 ybiM 7156367 ybiM Escherichia coli UMN026 hypothetical protein YP_002411703.1 987807 R 585056 CDS YP_002411704.1 218704185 7158457 988343..989269 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative SAM-dependent methyltransferase 989269 ybiN 7158457 ybiN Escherichia coli UMN026 putative SAM-dependent methyltransferase YP_002411704.1 988343 D 585056 CDS YP_002411705.1 218704186 7158458 complement(989266..991491) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 991491 ybiO 7158458 ybiO Escherichia coli UMN026 hypothetical protein YP_002411705.1 989266 R 585056 CDS YP_002411706.1 218704187 7158459 complement(991752..992474) 1 NC_011751.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 992474 glnQ 7158459 glnQ Escherichia coli UMN026 glutamine ABC transporter ATP-binding protein YP_002411706.1 991752 R 585056 CDS YP_002411707.1 218704188 7156557 complement(992471..993130) 1 NC_011751.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease protein 993130 glnP 7156557 glnP Escherichia coli UMN026 glutamine ABC transporter permease protein YP_002411707.1 992471 R 585056 CDS YP_002411708.1 218704189 7156556 complement(993269..994015) 1 NC_011751.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 994015 glnH 7156556 glnH Escherichia coli UMN026 glutamine ABC transporter periplasmic protein YP_002411708.1 993269 R 585056 CDS YP_002411709.1 218704190 7156553 complement(994419..994922) 1 NC_011751.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 994922 dps 7156553 dps Escherichia coli UMN026 DNA starvation/stationary phase protection protein Dps YP_002411709.1 994419 R 585056 CDS YP_002411710.1 218704191 7156200 complement(995221..996108) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12648727, 8021175; Product type t : transporter; threonine and homoserine efflux system 996108 rhtA 7156200 rhtA Escherichia coli UMN026 threonine and homoserine efflux system YP_002411710.1 995221 R 585056 CDS YP_002411711.1 218704192 7157679 996461..996976 1 NC_011751.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 996976 ompX 7157679 ompX Escherichia coli UMN026 outer membrane protein X YP_002411711.1 996461 D 585056 CDS YP_002411712.1 218704193 7157352 complement(997025..998608) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : putative enzyme; hypothetical protein 998608 ybiP 7157352 ybiP Escherichia coli UMN026 hypothetical protein YP_002411712.1 997025 R 585056 CDS YP_002411713.1 218704194 7157833 999459..1000040 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1000040 7157833 ECUMN_0960 Escherichia coli UMN026 hypothetical protein YP_002411713.1 999459 D 585056 CDS YP_002411714.1 218704195 7154804 complement(1000061..1001116) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3806670; Product type h : extrachromosomal origin; Integrase from bacteriophage origin 1001116 int 7154804 int Escherichia coli UMN026 Integrase from bacteriophage origin YP_002411714.1 1000061 R 585056 CDS YP_002411715.1 218704196 7156839 complement(1001118..1001699) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2370665; Product type h : extrachromosomal origin; repressor protein from bacteriophage origin 1001699 cI 7156839 cI Escherichia coli UMN026 repressor protein from bacteriophage origin YP_002411715.1 1001118 R 585056 CDS YP_002411716.1 218704197 7155962 1001835..1002056 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulator from bacteriophage origin 1002056 7155962 ECUMN_0963 Escherichia coli UMN026 putative regulator from bacteriophage origin YP_002411716.1 1001835 D 585056 CDS YP_002411717.1 218704198 7154805 1002087..1002590 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin 1002590 cII 7154805 cII Escherichia coli UMN026 regulatory protein from bacteriophage origin YP_002411717.1 1002087 D 585056 CDS YP_002411718.1 218704199 7155964 1002600..1002773 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1002773 7155964 ECUMN_0965 Escherichia coli UMN026 hypothetical protein YP_002411718.1 1002600 D 585056 CDS YP_002411719.1 218704200 7154806 1002782..1003210 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1003210 7154806 ECUMN_0966 Escherichia coli UMN026 hypothetical protein YP_002411719.1 1002782 D 585056 CDS YP_002411720.1 218704201 7154807 1003210..1003611 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1003611 7154807 ECUMN_0967 Escherichia coli UMN026 hypothetical protein YP_002411720.1 1003210 D 585056 CDS YP_002411721.1 218704202 7154808 1003679..1003912 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1003912 7154808 ECUMN_0968 Escherichia coli UMN026 hypothetical protein YP_002411721.1 1003679 D 585056 CDS YP_002411722.1 218704203 7154809 1003903..1004772 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; adenine-specific DNA-methyltransferase 1004772 7154809 ECUMN_0969 Escherichia coli UMN026 adenine-specific DNA-methyltransferase YP_002411722.1 1003903 D 585056 CDS YP_002411723.1 218704204 7154810 1004769..1004981 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1004981 7154810 ECUMN_0970 Escherichia coli UMN026 hypothetical protein YP_002411723.1 1004769 D 585056 CDS YP_002411724.1 218704205 7154811 1004947..1006998 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2352277; Product type h : extrachromosomal origin; replication gene A protein from bacteriophage origin 1006998 A 7154811 A Escherichia coli UMN026 replication gene A protein from bacteriophage origin YP_002411724.1 1004947 D 585056 CDS YP_002411725.1 218704206 7155653 1007118..1007324 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1007324 7155653 ECUMN_0972 Escherichia coli UMN026 hypothetical protein YP_002411725.1 1007118 D 585056 CDS YP_002411726.1 218704207 7154812 complement(1007298..1007621) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1007621 7154812 ECUMN_0973 Escherichia coli UMN026 hypothetical protein YP_002411726.1 1007298 R 585056 CDS YP_002411727.1 218704208 7154813 complement(1007618..1008679) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative portal vertex protein from bacteriophage origin 1008679 Q 7154813 Q Escherichia coli UMN026 putative portal vertex protein from bacteriophage origin YP_002411727.1 1007618 R 585056 CDS YP_002411728.1 218704209 7157607 complement(1008676..1010451) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Terminase, ATPase subunit from bacteriophage origin 1010451 P 7157607 P Escherichia coli UMN026 putative Terminase, ATPase subunit from bacteriophage origin YP_002411728.1 1008676 R 585056 CDS YP_002411729.1 218704210 7157372 1010613..1011416 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1837355; Product type h : extrachromosomal origin; putative capsid scaffolding protein from bacteriophage origin 1011416 7157372 ECUMN_0976 Escherichia coli UMN026 putative capsid scaffolding protein from bacteriophage origin YP_002411729.1 1010613 D 585056 CDS YP_002411730.1 218704211 7154814 1011478..1012500 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8874520; Product type h : extrachromosomal origin; putative major capsid protein from phage origin 1012500 7154814 ECUMN_0977 Escherichia coli UMN026 putative major capsid protein from phage origin YP_002411730.1 1011478 D 585056 CDS YP_002411731.1 218704212 7154815 1012504..1013205 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1837355; Product type h : extrachromosomal origin; putative terminase, endonuclease subunit from bacteriophage origin 1013205 7154815 ECUMN_0978 Escherichia coli UMN026 putative terminase, endonuclease subunit from bacteriophage origin YP_002411731.1 1012504 D 585056 CDS YP_002411732.1 218704213 7154816 1013251..1013754 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Head completion/stabilization protein (GpL) from bacteriophage origin 1013754 7154816 ECUMN_0979 Escherichia coli UMN026 putative Head completion/stabilization protein (GpL) from bacteriophage origin YP_002411732.1 1013251 D 585056 CDS YP_002411733.1 218704214 7154817 1013751..1014257 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1014257 7154817 ECUMN_0980 Escherichia coli UMN026 hypothetical protein YP_002411733.1 1013751 D 585056 CDS YP_002411734.1 218704215 7154818 1014254..1014961 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1014961 7154818 ECUMN_0981 Escherichia coli UMN026 hypothetical protein YP_002411734.1 1014254 D 585056 CDS YP_002411735.1 218704216 7154819 1014958..1016085 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail sheath protein from bacteriophage origin 1016085 7154819 ECUMN_0982 Escherichia coli UMN026 putative tail sheath protein from bacteriophage origin YP_002411735.1 1014958 D 585056 CDS YP_002411736.1 218704217 7154820 1016082..1016537 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail tube protein from bacteriophage origin 1016537 7154820 ECUMN_0983 Escherichia coli UMN026 putative tail tube protein from bacteriophage origin YP_002411736.1 1016082 D 585056 CDS YP_002411737.1 218704218 7154821 1016548..1016850 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8051010; Product type h : extrachromosomal origin; Holin from bacteriophage origin 1016850 7154821 ECUMN_0984 Escherichia coli UMN026 Holin from bacteriophage origin YP_002411737.1 1016548 D 585056 CDS YP_002411738.1 218704219 7154822 1016837..1017178 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1017178 7154822 ECUMN_0985 Escherichia coli UMN026 hypothetical protein YP_002411738.1 1016837 D 585056 CDS YP_002411739.1 218704220 7154823 1017178..1017558 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1017558 7154823 ECUMN_0986 Escherichia coli UMN026 hypothetical protein YP_002411739.1 1017178 D 585056 CDS YP_002411740.1 218704221 7154824 1017654..1017920 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1017920 7154824 ECUMN_0987 Escherichia coli UMN026 hypothetical protein YP_002411740.1 1017654 D 585056 CDS YP_002411741.1 218704222 7154825 1018108..1020168 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail tape measure protein from bacteriophage origin 1020168 7154825 ECUMN_0988 Escherichia coli UMN026 putative tail tape measure protein from bacteriophage origin YP_002411741.1 1018108 D 585056 CDS YP_002411742.1 218704223 7154826 1020165..1020494 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1020494 7154826 ECUMN_0989 Escherichia coli UMN026 hypothetical protein YP_002411742.1 1020165 D 585056 CDS YP_002411743.1 218704224 7154827 1020491..1021675 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1021675 7154827 ECUMN_0990 Escherichia coli UMN026 hypothetical protein YP_002411743.1 1020491 D 585056 CDS YP_002411744.1 218704225 7154828 1021662..1022255 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1022255 7154828 ECUMN_0991 Escherichia coli UMN026 hypothetical protein YP_002411744.1 1021662 D 585056 CDS YP_002411745.1 218704226 7154829 1022266..1024314 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1024314 7154829 ECUMN_0992 Escherichia coli UMN026 hypothetical protein YP_002411745.1 1022266 D 585056 CDS YP_002411746.1 218704227 7154830 1024281..1024733 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber assembly protein from bacteriophage origin 1024733 7154830 ECUMN_0993 Escherichia coli UMN026 putative tail fiber assembly protein from bacteriophage origin YP_002411746.1 1024281 D 585056 CDS YP_002411747.1 218704228 7154831 1024723..1025448 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1025448 7154831 ECUMN_0994 Escherichia coli UMN026 hypothetical protein YP_002411747.1 1024723 D 585056 CDS YP_002411748.1 218704229 7154832 1025420..1025965 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1025965 7154832 ECUMN_0995 Escherichia coli UMN026 hypothetical protein YP_002411748.1 1025420 D 585056 CDS YP_002411749.1 218704230 7154833 1025965..1027668 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1027668 7154833 ECUMN_0996 Escherichia coli UMN026 hypothetical protein YP_002411749.1 1025965 D 585056 CDS YP_002411750.1 218704231 7154834 complement(1028213..1028437) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1028437 7154834 ECUMN_0997 Escherichia coli UMN026 hypothetical protein YP_002411750.1 1028213 R 585056 CDS YP_002411751.1 218704232 7154835 complement(1028376..1029014) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1029014 7154835 ECUMN_0998 Escherichia coli UMN026 hypothetical protein YP_002411751.1 1028376 R 585056 CDS YP_002411752.1 218704233 7154836 complement(1029060..1029323) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1029323 7154836 ECUMN_0999 Escherichia coli UMN026 hypothetical protein YP_002411752.1 1029060 R 585056 CDS YP_002411753.1 218704234 7154837 complement(1029361..1029960) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1029960 7154837 ECUMN_1000 Escherichia coli UMN026 hypothetical protein YP_002411753.1 1029361 R 585056 CDS YP_002411754.1 218704235 7154838 1030164..1030631 1 NC_011751.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 1030631 mntR 7154838 mntR Escherichia coli UMN026 manganese transport regulator MntR YP_002411754.1 1030164 D 585056 CDS YP_002411755.1 218704236 7157144 1030628..1031746 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 1031746 ybiR 7157144 ybiR Escherichia coli UMN026 putative transporter YP_002411755.1 1030628 D 585056 CDS YP_002411756.1 218704237 7158461 complement(1031804..1032724) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646; hypothetical protein 1032724 ybiS 7158461 ybiS Escherichia coli UMN026 hypothetical protein YP_002411756.1 1031804 R 585056 CDS YP_002411757.1 218704238 7158462 1032943..1034538 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 1034538 ybiT 7158462 ybiT Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002411757.1 1032943 D 585056 CDS YP_002411758.1 218704239 7158463 complement(1034718..1037093) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glucosidase 1037093 7158463 ECUMN_1005 Escherichia coli UMN026 putative glucosidase YP_002411758.1 1034718 R 585056 CDS YP_002411759.1 218704240 7154839 complement(1037096..1038403) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12795379; Product type pt : putative transporter; putative hexuronate transporter 1038403 7154839 ECUMN_1006 Escherichia coli UMN026 putative hexuronate transporter YP_002411759.1 1037096 R 585056 CDS YP_002411760.1 218704241 7154840 complement(1038437..1038589) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1038589 7154840 ECUMN_1007 Escherichia coli UMN026 hypothetical protein YP_002411760.1 1038437 R 585056 CDS YP_002411761.1 218704242 7154841 1038614..1039795 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative transcriptional regulator 1039795 7154841 ECUMN_1008 Escherichia coli UMN026 putative transcriptional regulator YP_002411761.1 1038614 D 585056 CDS YP_002411762.1 218704243 7154842 complement(1039762..1041027) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1041027 ybiU 7154842 ybiU Escherichia coli UMN026 hypothetical protein YP_002411762.1 1039762 R 585056 CDS YP_002411763.1 218704244 7158464 complement(1041179..1041994) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme; type II HAD phosphatase 1041994 ybiV 7158464 ybiV Escherichia coli UMN026 type II HAD phosphatase YP_002411763.1 1041179 R 585056 CDS YP_002411764.1 218704245 7158465 complement(1042140..1044572) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : putative enzyme; putative glycyl radical cofactor protein 1044572 ybiW 7158465 ybiW Escherichia coli UMN026 putative glycyl radical cofactor protein YP_002411764.1 1042140 R 585056 CDS YP_002411765.1 218704246 7158466 complement(1044578..1045504) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : putative enzyme; putative AdoMet-dependent glycyl radical activating enzyme 1045504 ybiY 7158466 ybiY Escherichia coli UMN026 putative AdoMet-dependent glycyl radical activating enzyme YP_002411765.1 1044578 R 585056 CDS YP_002411766.1 218704247 7158468 1045608..1046270 1 NC_011751.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 1046270 fsaA 7158468 fsaA Escherichia coli UMN026 fructose-6-phosphate aldolase YP_002411766.1 1045608 D 585056 CDS YP_002411767.1 218704248 7156452 complement(1046346..1047095) 1 NC_011751.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1047095 moeB 7156452 moeB Escherichia coli UMN026 molybdopterin biosynthesis protein MoeB YP_002411767.1 1046346 R 585056 CDS YP_002411768.1 218704249 7157159 complement(1047095..1048330) 1 NC_011751.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 1048330 moeA 7157159 moeA Escherichia coli UMN026 molybdopterin biosynthesis protein MoeA YP_002411768.1 1047095 R 585056 CDS YP_002411769.1 218704250 7157158 1048534..1049499 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15159592, 20508248, 3045084, 7984428; Product type e : enzyme; L-asparaginase 1049499 iaaA 7157158 iaaA Escherichia coli UMN026 L-asparaginase YP_002411769.1 1048534 D 585056 CDS YP_002411770.1 218704251 7156777 1049519..1051357 1 NC_011751.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 1051357 yliA 7156777 yliA Escherichia coli UMN026 glutathione transporter ATP-binding protein YP_002411770.1 1049519 D 585056 CDS YP_002411771.1 218704252 7159463 1051377..1052915 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : putative transporter; putative peptide ABC transporter periplasmic-binding protein 1052915 yliB 7159463 yliB Escherichia coli UMN026 putative peptide ABC transporter periplasmic-binding protein YP_002411771.1 1051377 D 585056 CDS YP_002411772.1 218704253 7159464 1052933..1053853 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative peptide ABC transporter permease 1053853 yliC 7159464 yliC Escherichia coli UMN026 putative peptide ABC transporter permease YP_002411772.1 1052933 D 585056 CDS YP_002411773.1 218704254 7159465 1053856..1054767 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative peptide ABC transporter permease 1054767 yliD 7159465 yliD Escherichia coli UMN026 putative peptide ABC transporter permease YP_002411773.1 1053856 D 585056 CDS YP_002411774.1 218704255 7159466 1054945..1057293 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1057293 yliE 7159466 yliE Escherichia coli UMN026 hypothetical protein YP_002411774.1 1054945 D 585056 CDS YP_002411775.1 218704256 7159467 1057301..1058629 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pe : putative enzyme; putative diguanylate cyclase 1058629 yliF 7159467 yliF Escherichia coli UMN026 putative diguanylate cyclase YP_002411775.1 1057301 D 585056 CDS YP_002411776.1 218704257 7159468 complement(1058699..1059028) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1059028 7159468 ECUMN_1023 Escherichia coli UMN026 hypothetical protein YP_002411776.1 1058699 R 585056 CDS YP_002411777.1 218704258 7154843 complement(1059018..1059404) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1059404 7154843 ECUMN_1024 Escherichia coli UMN026 hypothetical protein YP_002411777.1 1059018 R 585056 CDS YP_002411778.1 218704259 7154844 complement(1059630..1060955) 1 NC_011751.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 1060955 rimO 7154844 rimO Escherichia coli UMN026 ribosomal protein S12 methylthiotransferase YP_002411778.1 1059630 R 585056 CDS YP_002411779.1 218704260 7159469 1061168..1061551 1 NC_011751.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1061551 bssR 7159469 bssR Escherichia coli UMN026 biofilm formation regulatory protein BssR YP_002411779.1 1061168 D 585056 CDS YP_002411780.1 218704261 7155892 1061662..1062777 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase (asd) 1062777 yliI 7155892 yliI Escherichia coli UMN026 PQQ-dependent aldose sugar dehydrogenase (asd) YP_002411780.1 1061662 D 585056 CDS YP_002411781.1 218704262 7159470 complement(1062774..1063400) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glutathione S-transferase 1063400 yliJ 7159470 yliJ Escherichia coli UMN026 putative glutathione S-transferase YP_002411781.1 1062774 R 585056 CDS YP_002411782.1 218704263 7159471 1063647..1064849 1 NC_011751.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 1064849 dacC 7159471 dacC Escherichia coli UMN026 D-alanyl-D-alanine carboxypeptidase fraction C YP_002411782.1 1063647 D 585056 CDS YP_002411783.1 218704264 7156101 complement(1064896..1065654) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator; DNA-binding transcriptional repressor DeoR 1065654 deoR 7156101 deoR Escherichia coli UMN026 DNA-binding transcriptional repressor DeoR YP_002411783.1 1064896 R 585056 CDS YP_002411784.1 218704265 7156144 complement(1065712..1066308) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 1066308 ybjG 7156144 ybjG Escherichia coli UMN026 undecaprenyl pyrophosphate phosphatase YP_002411784.1 1065712 R 585056 CDS YP_002411785.1 218704266 7158472 1066593..1067825 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter; multidrug efflux system protein 1067825 cmr 7158472 cmr Escherichia coli UMN026 multidrug efflux system protein YP_002411785.1 1066593 D 585056 CDS YP_002411786.1 218704267 7155985 complement(1067866..1068150) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1068150 ybjH 7155985 ybjH Escherichia coli UMN026 hypothetical protein YP_002411786.1 1067866 R 585056 CDS YP_002411787.1 218704268 7158473 complement(1068235..1069050) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; putative phosphatase 1069050 ybjI 7158473 ybjI Escherichia coli UMN026 putative phosphatase YP_002411787.1 1068235 R 585056 CDS YP_002411788.1 218704269 7158474 complement(1069050..1070258) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 1070258 ybjJ 7158474 ybjJ Escherichia coli UMN026 putative transporter YP_002411788.1 1069050 R 585056 CDS YP_002411789.1 218704270 7158475 1070342..1070878 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1070878 ybjK 7158475 ybjK Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002411789.1 1070342 D 585056 CDS YP_002411790.1 218704271 7157834 complement(1071053..1072738) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 1072738 ybjL 7157834 ybjL Escherichia coli UMN026 hypothetical protein YP_002411790.1 1071053 R 585056 CDS YP_002411791.1 218704272 7158477 1073008..1073385 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1073385 ybjM 7158477 ybjM Escherichia coli UMN026 hypothetical protein YP_002411791.1 1073008 D 585056 CDS YP_002411792.1 218704273 7158478 complement(1073415..1073672) 1 NC_011751.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 1073672 grxA 7158478 grxA Escherichia coli UMN026 glutaredoxin 1 YP_002411792.1 1073415 R 585056 CDS YP_002411793.1 218704274 7156614 1073832..1074119 1 NC_011751.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1074119 ybjC 7156614 ybjC Escherichia coli UMN026 hypothetical protein YP_002411793.1 1073832 D 585056 CDS YP_002411794.1 218704275 7158469 1074103..1074825 1 NC_011751.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1074825 nfsA 7158469 nfsA Escherichia coli UMN026 nitroreductase A YP_002411794.1 1074103 D 585056 CDS YP_002411795.1 218704276 7157270 1074886..1075788 1 NC_011751.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1075788 rimK 7157270 rimK Escherichia coli UMN026 ribosomal protein S6 modification protein YP_002411795.1 1074886 D 585056 CDS YP_002411796.1 218704277 7157693 1075876..1076352 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1076352 ybjN 7157693 ybjN Escherichia coli UMN026 hypothetical protein YP_002411796.1 1075876 D 585056 CDS YP_002411797.1 218704278 7158479 1076703..1077815 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter; putrescine ABC transporter periplasmic-binding protein 1077815 potF 7158479 potF Escherichia coli UMN026 putrescine ABC transporter periplasmic-binding protein YP_002411797.1 1076703 D 585056 CDS YP_002411798.1 218704279 7157491 1077910..1079043 1 NC_011751.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 1079043 potG 7157491 potG Escherichia coli UMN026 putrescine transporter ATP-binding subunit YP_002411798.1 1077910 D 585056 CDS YP_002411799.1 218704280 7157492 1079053..1079997 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1079997 potH 7157492 potH Escherichia coli UMN026 putrescine ABC transporter membrane protein YP_002411799.1 1079053 D 585056 CDS YP_002411800.1 218704281 7157493 1079994..1080839 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1080839 potI 7157493 potI Escherichia coli UMN026 putrescine ABC transporter membrane protein YP_002411800.1 1079994 D 585056 CDS YP_002411801.1 218704282 7157494 1080899..1081387 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1081387 ybjO 7157494 ybjO Escherichia coli UMN026 hypothetical protein YP_002411801.1 1080899 D 585056 CDS YP_002411802.1 218704283 7158480 1081428..1082555 1 NC_011751.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1082555 rumB 7158480 rumB Escherichia coli UMN026 23S rRNA methyluridine methyltransferase YP_002411802.1 1081428 D 585056 CDS YP_002411803.1 218704284 7157818 1082836..1084179 1 NC_011751.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 1084179 7157818 ECUMN_1050 Escherichia coli UMN026 PTS system ascorbate-specific transporter subunit IIC YP_002411803.1 1082836 D 585056 CDS YP_002411804.1 218704285 7154845 1084201..1084521 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase enzyme II, B component 1084521 7154845 ECUMN_1051 Escherichia coli UMN026 putative phosphotransferase enzyme II, B component YP_002411804.1 1084201 D 585056 CDS YP_002411805.1 218704286 7154846 1084534..1086015 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase 1086015 7154846 ECUMN_1052 Escherichia coli UMN026 putative sulfatase YP_002411805.1 1084534 D 585056 CDS YP_002411806.1 218704287 7154847 complement(1086066..1086797) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter; arginine ABC transporter periplasmic-binding protein 1086797 artJ 7154847 artJ Escherichia coli UMN026 arginine ABC transporter periplasmic-binding protein YP_002411806.1 1086066 R 585056 CDS YP_002411807.1 218704288 7155802 complement(1087023..1087691) 1 NC_011751.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine permease ArtM 1087691 artM 7155802 artM Escherichia coli UMN026 arginine permease ArtM YP_002411807.1 1087023 R 585056 CDS YP_002411808.1 218704289 7155803 complement(1087691..1088407) 1 NC_011751.1 with ArtPMJI transports arginine across the inner membrane; arginine permease ArtQ 1088407 artQ 7155803 artQ Escherichia coli UMN026 arginine permease ArtQ YP_002411808.1 1087691 R 585056 CDS YP_002411809.1 218704290 7155805 complement(1088414..1089145) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter; arginine ABC transporter periplasmic-binding protein 1089145 artI 7155805 artI Escherichia coli UMN026 arginine ABC transporter periplasmic-binding protein YP_002411809.1 1088414 R 585056 CDS YP_002411810.1 218704291 7155801 complement(1089163..1089891) 1 NC_011751.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1089891 artP 7155801 artP Escherichia coli UMN026 arginine transporter ATP-binding subunit YP_002411810.1 1089163 R 585056 CDS YP_002411811.1 218704292 7155804 complement(1090109..1090624) 1 NC_011751.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein 1090624 ybjP 7155804 ybjP Escherichia coli UMN026 putative lipoprotein YP_002411811.1 1090109 R 585056 CDS YP_002411812.1 218704293 7158481 complement(1090638..1090820) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1090820 7158481 ECUMN_1059 Escherichia coli UMN026 hypothetical protein YP_002411812.1 1090638 R 585056 CDS YP_002411813.1 218704294 7154848 1091239..1093041 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1093041 7154848 ECUMN_1060 Escherichia coli UMN026 hypothetical protein YP_002411813.1 1091239 D 585056 CDS YP_002411814.1 218704295 7154849 1093252..1093575 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1093575 ybjQ 7154849 ybjQ Escherichia coli UMN026 hypothetical protein YP_002411814.1 1093252 D 585056 CDS YP_002411815.1 218704296 7158482 1093572..1094402 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative cell wall amidase and lipoprotein 1094402 ybjR 7158482 ybjR Escherichia coli UMN026 putative cell wall amidase and lipoprotein YP_002411815.1 1093572 D 585056 CDS YP_002411816.1 218704297 7158483 complement(1094399..1095412) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain 1095412 ybjS 7158483 ybjS Escherichia coli UMN026 putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain YP_002411816.1 1094399 R 585056 CDS YP_002411817.1 218704298 7158484 complement(1095511..1096941) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1096941 ybjT 7158484 ybjT Escherichia coli UMN026 hypothetical protein YP_002411817.1 1095511 R 585056 CDS YP_002411818.1 218704299 7158485 complement(1096952..1097953) 1 NC_011751.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 1097953 ltaE 7158485 ltaE Escherichia coli UMN026 L-threonine aldolase YP_002411818.1 1096952 R 585056 CDS YP_002411819.1 218704300 7157027 complement(1097990..1099708) 1 NC_011751.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1099708 poxB 7157027 poxB Escherichia coli UMN026 pyruvate dehydrogenase YP_002411819.1 1097990 R 585056 CDS YP_002411820.1 218704301 7157496 complement(1099841..1100809) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme; HCP oxidoreductase, NADH-dependent 1100809 hcr 7157496 hcr Escherichia coli UMN026 HCP oxidoreductase, NADH-dependent YP_002411820.1 1099841 R 585056 CDS YP_002411821.1 218704302 7156642 complement(1100821..1102473) 1 NC_011751.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1102473 hcp 7156642 hcp Escherichia coli UMN026 hydroxylamine reductase YP_002411821.1 1100821 R 585056 CDS YP_002411822.1 218704303 7156641 complement(1102617..1103516) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 1103516 ybjE 7156641 ybjE Escherichia coli UMN026 putative transporter YP_002411822.1 1102617 R 585056 CDS YP_002411823.1 218704304 7158471 complement(1104000..1104695) 1 NC_011751.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1104695 aqpZ 7158471 aqpZ Escherichia coli UMN026 aquaporin Z YP_002411823.1 1104000 R 585056 CDS YP_002411824.1 218704305 7155756 1105121..1106779 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1106779 ybjD 7155756 ybjD Escherichia coli UMN026 hypothetical protein YP_002411824.1 1105121 D 585056 CDS YP_002411825.1 218704306 7158470 complement(1106776..1107768) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1107768 ybjX 7158470 ybjX Escherichia coli UMN026 hypothetical protein YP_002411825.1 1106776 R 585056 CDS YP_002411826.1 218704307 7158486 1107883..1108998 1 NC_011751.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1108998 macA 7158486 macA Escherichia coli UMN026 macrolide transporter subunit MacA YP_002411826.1 1107883 D 585056 CDS YP_002411827.1 218704308 7157037 1108995..1110941 1 NC_011751.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease protein 1110941 macB 7157037 macB Escherichia coli UMN026 macrolide transporter ATP-binding /permease protein YP_002411827.1 1108995 D 585056 CDS YP_002411828.1 218704309 7157038 complement(1111013..1111237) 1 NC_011751.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD 1111237 cspD 7157038 cspD Escherichia coli UMN026 stationary phase/starvation inducible regulatory protein CspD YP_002411828.1 1111013 R 585056 CDS YP_002411829.1 218704310 7156037 1111560..1111880 1 NC_011751.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1111880 clpS 7156037 clpS Escherichia coli UMN026 ATP-dependent Clp protease adaptor protein ClpS YP_002411829.1 1111560 D 585056 CDS YP_002411830.1 218704311 7155981 1111911..1114187 1 NC_011751.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1114187 clpA 7155981 clpA Escherichia coli UMN026 ATP-dependent Clp protease ATP-binding subunit YP_002411830.1 1111911 D 585056 CDS YP_002411831.1 218704312 7155978 complement(1114305..1114703) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1114703 7155978 ECUMN_1078 Escherichia coli UMN026 hypothetical protein YP_002411831.1 1114305 R 585056 CDS YP_002411832.1 218704313 7155644 complement(1115348..1115566) 1 NC_011751.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1115566 infA 7155644 infA Escherichia coli UMN026 translation initiation factor IF-1 YP_002411832.1 1115348 R 585056 CDS YP_002411833.1 218704314 7156811 complement(1115851..1116555) 1 NC_011751.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA --protein transferase 1116555 aat 7156811 aat Escherichia coli UMN026 leucyl/phenylalanyl-tRNA --protein transferase YP_002411833.1 1115851 R 585056 CDS YP_002411834.1 218704315 7155665 complement(1116597..1118318) 1 NC_011751.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 1118318 cydC 7155665 cydC Escherichia coli UMN026 cysteine/glutathione ABC transporter membrane/ATP-binding component YP_002411834.1 1116597 R 585056 CDS YP_002411835.1 218704316 7156067 complement(1118319..1120085) 1 NC_011751.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component 1120085 cydD 7156067 cydD Escherichia coli UMN026 cysteine/glutathione ABC transporter membrane/ATP-binding component YP_002411835.1 1118319 R 585056 CDS YP_002411836.1 218704317 7156068 complement(1120208..1121173) 1 NC_011751.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 1121173 trxB 7156068 trxB Escherichia coli UMN026 thioredoxin reductase YP_002411836.1 1120208 R 585056 CDS YP_002411837.1 218704318 7158130 1121719..1122213 1 NC_011751.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1122213 lrp 7158130 lrp Escherichia coli UMN026 leucine-responsive transcriptional regulator YP_002411837.1 1121719 D 585056 CDS YP_002411838.1 218704319 7157018 1122348..1126454 1 NC_011751.1 DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 1126454 ftsK 7157018 ftsK Escherichia coli UMN026 DNA translocase FtsK YP_002411838.1 1122348 D 585056 CDS YP_002411839.1 218704320 7156461 1126610..1127224 1 NC_011751.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1127224 lolA 7156461 lolA Escherichia coli UMN026 outer-membrane lipoprotein carrier protein YP_002411839.1 1126610 D 585056 CDS YP_002411840.1 218704321 7156994 1127235..1128578 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process; recombination factor protein RarA 1128578 ycaJ 7156994 ycaJ Escherichia coli UMN026 recombination factor protein RarA YP_002411840.1 1127235 D 585056 CDS YP_002411841.1 218704322 7158491 1128669..1129961 1 NC_011751.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1129961 serS 7158491 serS Escherichia coli UMN026 seryl-tRNA synthetase YP_002411841.1 1128669 D 585056 CDS YP_002411842.1 218704323 7157900 1130200..1132644 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 94171715, 10801884, 3062312; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit A 1132644 dmsA 7157900 dmsA Escherichia coli UMN026 dimethyl sulfoxide reductase, anaerobic, subunit A YP_002411842.1 1130200 D 585056 CDS YP_002411843.1 218704324 7156179 1132655..1133272 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91070067, 91355180, 92011349, 3062312; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit B 1133272 dmsB 7156179 dmsB Escherichia coli UMN026 dimethyl sulfoxide reductase, anaerobic, subunit B YP_002411843.1 1132655 D 585056 CDS YP_002411844.1 218704325 7156180 1133274..1134137 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 3062312, 8429002; Product type e : enzyme; dimethyl sulfoxide reductase, anaerobic, subunit C 1134137 dmsC 7156180 dmsC Escherichia coli UMN026 dimethyl sulfoxide reductase, anaerobic, subunit C YP_002411844.1 1133274 D 585056 CDS YP_002411845.1 218704326 7156181 complement(1134173..1134799) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : putative enzyme; putative hydrolase 1134799 ycaC 7156181 ycaC Escherichia coli UMN026 putative hydrolase YP_002411845.1 1134173 R 585056 CDS YP_002411846.1 218704327 7158488 1135114..1136262 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS family transporter protein 1136262 ycaD 7158488 ycaD Escherichia coli UMN026 putative MFS family transporter protein YP_002411846.1 1135114 D 585056 CDS YP_002411847.1 218704328 7158489 1136472..1137902 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pt : putative transporter; putative transporter 1137902 ycaM 7158489 ycaM Escherichia coli UMN026 putative transporter YP_002411847.1 1136472 D 585056 CDS YP_002411848.1 218704329 7158493 complement(1138112..1138852) 1 NC_011751.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1138852 pflA 7158493 pflA Escherichia coli UMN026 pyruvate formate lyase-activating enzyme 1 YP_002411848.1 1138112 R 585056 CDS YP_002411849.1 218704330 7157421 complement(1139044..1141326) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme; pyruvate formate lyase I 1141326 pflB 7157421 pflB Escherichia coli UMN026 pyruvate formate lyase I YP_002411849.1 1139044 R 585056 CDS YP_002411850.1 218704331 7157422 complement(1141381..1142238) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter; formate transporter 1142238 focA 7157422 focA Escherichia coli UMN026 formate transporter YP_002411850.1 1141381 R 585056 CDS YP_002411851.1 218704332 7156421 complement(1142644..1144404) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1144404 ycaO 7156421 ycaO Escherichia coli UMN026 hypothetical protein YP_002411851.1 1142644 R 585056 CDS YP_002411852.1 218704333 7158494 1144534..1145226 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1145226 ycaP 7158494 ycaP Escherichia coli UMN026 hypothetical protein YP_002411852.1 1144534 D 585056 CDS YP_002411853.1 218704334 7158495 1145425..1146513 1 NC_011751.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1146513 serC 7158495 serC Escherichia coli UMN026 phosphoserine aminotransferase YP_002411853.1 1145425 D 585056 CDS YP_002411854.1 218704335 7157899 1146584..1147867 1 NC_011751.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1147867 aroA 7157899 aroA Escherichia coli UMN026 3-phosphoshikimate 1-carboxyvinyltransferase YP_002411854.1 1146584 D 585056 CDS YP_002411855.1 218704336 7155783 1148037..1148801 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative lipoprotein with metallohydrolase domain 1148801 ycaL 7155783 ycaL Escherichia coli UMN026 putative lipoprotein with metallohydrolase domain YP_002411855.1 1148037 D 585056 CDS YP_002411856.1 218704337 7158492 1148974..1149657 1 NC_011751.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1149657 cmk 7158492 cmk Escherichia coli UMN026 cytidylate kinase YP_002411856.1 1148974 D 585056 CDS YP_002411857.1 218704338 7155984 1149768..1151441 1 NC_011751.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1151441 rpsA 7155984 rpsA Escherichia coli UMN026 30S ribosomal protein S1 YP_002411857.1 1149768 D 585056 CDS YP_002411858.1 218704339 7157767 1151601..1151885 1 NC_011751.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1151885 ihfB 7157767 ihfB Escherichia coli UMN026 integration host factor subunit beta YP_002411858.1 1151601 D 585056 CDS YP_002411859.1 218704340 7156795 1152092..1154356 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1154356 ycaI 7156795 ycaI Escherichia coli UMN026 hypothetical protein YP_002411859.1 1152092 D 585056 CDS YP_002411860.1 218704341 7158490 1154393..1156141 1 NC_011751.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease protein 1156141 msbA 7158490 msbA Escherichia coli UMN026 lipid transporter ATP-binding/permease protein YP_002411860.1 1154393 D 585056 CDS YP_002411861.1 218704342 7157184 1156138..1157124 1 NC_011751.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1157124 lpxK 7157184 lpxK Escherichia coli UMN026 tetraacyldisaccharide 4'-kinase YP_002411861.1 1156138 D 585056 CDS YP_002411862.1 218704343 7157014 1157161..1158393 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1158393 ycaQ 7157014 ycaQ Escherichia coli UMN026 hypothetical protein YP_002411862.1 1157161 D 585056 CDS YP_002411863.1 218704344 7158496 1158445..1158627 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1158627 ycaR 7158496 ycaR Escherichia coli UMN026 hypothetical protein YP_002411863.1 1158445 D 585056 CDS YP_002411864.1 218704345 7158497 1158624..1159370 1 NC_011751.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1159370 kdsB 7158497 kdsB Escherichia coli UMN026 3-deoxy-manno-octulosonate cytidylyltransferase YP_002411864.1 1158624 D 585056 CDS YP_002411865.1 218704346 7156896 1159524..1160417 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1160417 ycbJ 7156896 ycbJ Escherichia coli UMN026 hypothetical protein YP_002411865.1 1159524 D 585056 CDS YP_002411866.1 218704347 7158501 complement(1160394..1161173) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1161173 ycbC 7158501 ycbC Escherichia coli UMN026 hypothetical protein YP_002411866.1 1160394 R 585056 CDS YP_002411867.1 218704348 7158499 complement(1161076..1161240) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1161240 7158499 ECUMN_1114 Escherichia coli UMN026 hypothetical protein YP_002411867.1 1161076 R 585056 CDS YP_002411868.1 218704349 7154851 1161309..1162094 1 NC_011751.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 1162094 smtA 7154851 smtA Escherichia coli UMN026 putative metallothionein SmtA YP_002411868.1 1161309 D 585056 CDS YP_002411869.1 218704350 7157944 1162091..1163413 1 NC_011751.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1163413 mukF 7157944 mukF Escherichia coli UMN026 condesin subunit F YP_002411869.1 1162091 D 585056 CDS YP_002411870.1 218704351 7157200 1163421..1164098 1 NC_011751.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1164098 mukE 7157200 mukE Escherichia coli UMN026 condesin subunit E YP_002411870.1 1163421 D 585056 CDS YP_002411871.1 218704352 7157199 1164098..1168558 1 NC_011751.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1168558 mukB 7157199 mukB Escherichia coli UMN026 cell division protein MukB YP_002411871.1 1164098 D 585056 CDS YP_002411872.1 218704353 7157198 1168819..1170666 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 1170666 ycbB 7157198 ycbB Escherichia coli UMN026 hypothetical protein YP_002411872.1 1168819 D 585056 CDS YP_002411873.1 218704354 7158498 1170847..1171395 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1171395 ycbK 7158498 ycbK Escherichia coli UMN026 hypothetical protein YP_002411873.1 1170847 D 585056 CDS YP_002411874.1 218704355 7158502 1171422..1172069 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : putative enzyme; putative metal-binding hydrolase 1172069 ycbL 7158502 ycbL Escherichia coli UMN026 putative metal-binding hydrolase YP_002411874.1 1171422 D 585056 CDS YP_002411875.1 218704356 7158503 complement(1172120..1173310) 1 NC_011751.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1173310 aspC 7158503 aspC Escherichia coli UMN026 aromatic amino acid aminotransferase YP_002411875.1 1172120 R 585056 CDS YP_002411876.1 218704357 7155818 complement(1173495..1174583) 1 NC_011751.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1174583 ompF 7155818 ompF Escherichia coli UMN026 outer membrane protein F YP_002411876.1 1173495 R 585056 CDS YP_002411877.1 218704358 7157346 complement(1175186..1176586) 1 NC_011751.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1176586 asnC 7157346 asnC Escherichia coli UMN026 asparaginyl-tRNA synthetase YP_002411877.1 1175186 R 585056 CDS YP_002411878.1 218704359 7155816 complement(1176755..1177957) 1 NC_011751.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1177957 pncB 7155816 pncB Escherichia coli UMN026 nicotinate phosphoribosyltransferase YP_002411878.1 1176755 R 585056 CDS YP_002411879.1 218704360 7157479 1178223..1180835 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme; aminopeptidase N 1180835 pepN 7157479 pepN Escherichia coli UMN026 aminopeptidase N YP_002411879.1 1178223 D 585056 CDS YP_002411880.1 218704361 7157414 1180914..1181444 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 1181444 7157414 ECUMN_1127 Escherichia coli UMN026 transposase ORF A, IS1397 YP_002411880.1 1180914 D 585056 CDS YP_002411881.1 218704362 7154852 1181549..1182271 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 1182271 7154852 ECUMN_1128 Escherichia coli UMN026 transposase ORF B, IS3 family, IS150 group YP_002411881.1 1181549 D 585056 CDS YP_002411882.1 218704363 7154853 complement(1182477..1183244) 1 NC_011751.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1183244 ssuB 7154853 ssuB Escherichia coli UMN026 aliphatic sulfonates transport ATP-binding subunit YP_002411882.1 1182477 R 585056 CDS YP_002411883.1 218704364 7157992 complement(1183241..1184032) 1 NC_011751.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate permease 1184032 ssuC 7157992 ssuC Escherichia coli UMN026 alkanesulfonate permease YP_002411883.1 1183241 R 585056 CDS YP_002411884.1 218704365 7157993 complement(1184044..1185189) 1 NC_011751.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1185189 ssuD 7157993 ssuD Escherichia coli UMN026 alkanesulfonate monooxygenase YP_002411884.1 1184044 R 585056 CDS YP_002411885.1 218704366 7157994 complement(1185186..1186145) 1 NC_011751.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1186145 ssuA 7157994 ssuA Escherichia coli UMN026 alkanesulfonate transporter substrate-binding subunit YP_002411885.1 1185186 R 585056 CDS YP_002411886.1 218704367 7157991 complement(1186138..1186713) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme; NAD(P)H-dependent FMN reductase 1186713 ssuE 7157991 ssuE Escherichia coli UMN026 NAD(P)H-dependent FMN reductase YP_002411886.1 1186138 R 585056 CDS YP_002411887.1 218704368 7157995 1186950..1187960 1 NC_011751.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1187960 pyrD 7157995 pyrD Escherichia coli UMN026 dihydroorotate dehydrogenase 2 YP_002411887.1 1186950 D 585056 CDS YP_002411888.1 218704369 7157599 1188134..1188676 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1188676 ycbW 7157599 ycbW Escherichia coli UMN026 hypothetical protein YP_002411888.1 1188134 D 585056 CDS YP_002411889.1 218704370 7158504 complement(1188673..1189782) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : putative enzyme; putative 2Fe-2S cluster-containing protein 1189782 ycbX 7158504 ycbX Escherichia coli UMN026 putative 2Fe-2S cluster-containing protein YP_002411889.1 1188673 R 585056 CDS YP_002411890.1 218704371 7158505 1190026..1192134 1 NC_011751.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1192134 rlmL 7158505 rlmL Escherichia coli UMN026 23S rRNA m(2)G2445 methyltransferase YP_002411890.1 1190026 D 585056 CDS YP_002411891.1 218704372 7158506 1192146..1194053 1 NC_011751.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1194053 uup 7158506 uup Escherichia coli UMN026 ABC transporter ATPase YP_002411891.1 1192146 D 585056 CDS YP_002411892.1 218704373 7158197 1194183..1195436 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible membrane protein A 1195436 pqiA 7158197 pqiA Escherichia coli UMN026 paraquat-inducible membrane protein A YP_002411892.1 1194183 D 585056 CDS YP_002411893.1 218704374 7157513 1195441..1197081 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible protein B 1197081 pqiB 7157513 pqiB Escherichia coli UMN026 paraquat-inducible protein B YP_002411893.1 1195441 D 585056 CDS YP_002411894.1 218704375 7157514 1197093..1197641 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1197641 ymbA 7157514 ymbA Escherichia coli UMN026 hypothetical protein YP_002411894.1 1197093 D 585056 CDS YP_002411895.1 218704376 7159473 1197897..1198064 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor; ribosome modulation factor 1198064 rmf 7159473 rmf Escherichia coli UMN026 ribosome modulation factor YP_002411895.1 1197897 D 585056 CDS YP_002411896.1 218704377 7157703 complement(1198134..1198652) 1 NC_011751.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 1198652 fabA 7157703 fabA Escherichia coli UMN026 3-hydroxydecanoyl-(acyl carrier protein) dehydratase YP_002411896.1 1198134 R 585056 CDS YP_002411897.1 218704378 7156293 complement(1198721..1200481) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-dependent protease 1200481 ycbZ 7156293 ycbZ Escherichia coli UMN026 putative ATP-dependent protease YP_002411897.1 1198721 R 585056 CDS YP_002411898.1 218704379 7158507 1200667..1201119 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1201119 ycbG 7158507 ycbG Escherichia coli UMN026 hypothetical protein YP_002411898.1 1200667 D 585056 CDS YP_002411899.1 218704380 7158500 complement(1201195..1202235) 1 NC_011751.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1202235 ompA 7158500 ompA Escherichia coli UMN026 outer membrane protein A YP_002411899.1 1201195 R 585056 CDS YP_002411900.1 218704381 7157344 1202389..1202607 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1202607 7157344 ECUMN_1147 Escherichia coli UMN026 hypothetical protein YP_002411900.1 1202389 D 585056 CDS YP_002411901.1 218704382 7156861 complement(1202591..1203100) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process; SOS cell division inhibitor 1203100 sulA 7156861 sulA Escherichia coli UMN026 SOS cell division inhibitor YP_002411901.1 1202591 R 585056 CDS YP_002411902.1 218704383 7158011 1203319..1203948 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1203948 yccR 7158011 yccR Escherichia coli UMN026 hypothetical protein YP_002411902.1 1203319 D 585056 CDS YP_002411903.1 218704384 7158513 complement(1203911..1206064) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1206064 yccS 7158513 yccS Escherichia coli UMN026 hypothetical protein YP_002411903.1 1203911 R 585056 CDS YP_002411904.1 218704385 7158514 complement(1206083..1206529) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1206529 yccF 7158514 yccF Escherichia coli UMN026 hypothetical protein YP_002411904.1 1206083 R 585056 CDS YP_002411905.1 218704386 7158510 1206652..1208706 1 NC_011751.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1208706 helD 7158510 helD Escherichia coli UMN026 DNA helicase IV YP_002411905.1 1206652 D 585056 CDS YP_002411906.1 218704387 7156649 complement(1208738..1209196) 1 NC_011751.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1209196 mgsA 7156649 mgsA Escherichia coli UMN026 methylglyoxal synthase YP_002411906.1 1208738 R 585056 CDS YP_002411907.1 218704388 7157118 complement(1209292..1209954) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1209954 yccT 7157118 yccT Escherichia coli UMN026 hypothetical protein YP_002411907.1 1209292 R 585056 CDS YP_002411908.1 218704389 7158515 1210127..1210540 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative CoA-binding protein 1210540 yccU 7158515 yccU Escherichia coli UMN026 putative CoA-binding protein YP_002411908.1 1210127 D 585056 CDS YP_002411909.1 218704390 7158516 complement(1210585..1210902) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor; heat shock protein HspQ 1210902 yccV 7158516 yccV Escherichia coli UMN026 heat shock protein HspQ YP_002411909.1 1210585 R 585056 CDS YP_002411910.1 218704391 7158517 complement(1210960..1212063) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AdoMet-dependent methyltransferase, UPF0064 family 1212063 yccW 7158517 yccW Escherichia coli UMN026 putative AdoMet-dependent methyltransferase, UPF0064 family YP_002411910.1 1210960 R 585056 CDS YP_002411911.1 218704392 7158518 1212032..1212523 1 NC_011751.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1212523 yccX 7158518 yccX Escherichia coli UMN026 acylphosphatase YP_002411911.1 1212032 D 585056 CDS YP_002411912.1 218704393 7158519 complement(1212520..1212849) 1 NC_011751.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1212849 tusE 7158519 tusE Escherichia coli UMN026 sulfur transfer protein TusE YP_002411912.1 1212520 R 585056 CDS YP_002411913.1 218704394 7158146 complement(1212940..1213599) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component; hypothetical protein 1213599 yccA 7158146 yccA Escherichia coli UMN026 hypothetical protein YP_002411913.1 1212940 R 585056 CDS YP_002411914.1 218704395 7158508 complement(1213801..1213977) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1213977 7158508 ECUMN_1161 Escherichia coli UMN026 hypothetical protein YP_002411914.1 1213801 R 585056 CDS YP_002411915.1 218704396 7155643 1214320..1215438 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme; hydrogenase 1, small subunit 1215438 hyaA 7155643 hyaA Escherichia coli UMN026 hydrogenase 1, small subunit YP_002411915.1 1214320 D 585056 CDS YP_002411916.1 218704397 7156734 1215435..1217228 1 NC_011751.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1217228 hyaB 7156734 hyaB Escherichia coli UMN026 hydrogenase 1 large subunit YP_002411916.1 1215435 D 585056 CDS YP_002411917.1 218704398 7156735 1217247..1217954 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier; hydrogenase 1 b-type cytochrome subunit 1217954 hyaC 7156735 hyaC Escherichia coli UMN026 hydrogenase 1 b-type cytochrome subunit YP_002411917.1 1217247 D 585056 CDS YP_002411918.1 218704399 7156736 1217951..1218538 1 NC_011751.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1218538 hyaD 7156736 hyaD Escherichia coli UMN026 hydrogenase 1 maturation protease YP_002411918.1 1217951 D 585056 CDS YP_002411919.1 218704400 7156737 1218535..1218933 1 NC_011751.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1218933 hyaE 7156737 hyaE Escherichia coli UMN026 hydrogenase-1 operon protein HyaE YP_002411919.1 1218535 D 585056 CDS YP_002411920.1 218704401 7156738 1218930..1219787 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor; protein involved in nickel incorporation into hydrogenase-1 proteins 1219787 hyaF 7156738 hyaF Escherichia coli UMN026 protein involved in nickel incorporation into hydrogenase-1 proteins YP_002411920.1 1218930 D 585056 CDS YP_002411921.1 218704402 7156739 1219921..1221465 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase, subunit I 1221465 appC 7156739 appC Escherichia coli UMN026 cytochrome bd-II oxidase, subunit I YP_002411921.1 1219921 D 585056 CDS YP_002411922.1 218704403 7155753 1221477..1222613 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase, subunit II 1222613 appB 7155753 appB Escherichia coli UMN026 cytochrome bd-II oxidase, subunit II YP_002411922.1 1221477 D 585056 CDS YP_002411923.1 218704404 7155752 1222810..1224108 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20122624, 92049231, 93054596, 10696472, 2168385, 3038201, 8387749; Product type e : enzyme; phosphoanhydride phosphorylase 1224108 appA 7155752 appA Escherichia coli UMN026 phosphoanhydride phosphorylase YP_002411923.1 1222810 D 585056 CDS YP_002411924.1 218704405 7155751 complement(1224096..1224308) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9484881, 9439003; Product type f : factor; stress protein, member of the CspA-family 1224308 cspH 7155751 cspH Escherichia coli UMN026 stress protein, member of the CspA-family YP_002411924.1 1224096 R 585056 CDS YP_002411925.1 218704406 7156041 1224594..1224806 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 15466053, 8631696, 9439003; Product type r : regulator; cold shock protein CspG 1224806 cspG 7156041 cspG Escherichia coli UMN026 cold shock protein CspG YP_002411925.1 1224594 D 585056 CDS YP_002411926.1 218704407 7156040 1225200..1225373 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15317805, 11544213; Product type pr : putative regulator; putative regulator of phosphatidylethanolamine synthesis 1225373 gnsA 7156040 gnsA Escherichia coli UMN026 putative regulator of phosphatidylethanolamine synthesis YP_002411926.1 1225200 D 585056 CDS YP_002411927.1 218704408 7156593 complement(1225422..1226495) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S membrane protein 1226495 yccM 7156593 yccM Escherichia coli UMN026 putative 4Fe-4S membrane protein YP_002411927.1 1225422 R 585056 CDS YP_002411928.1 218704409 7158512 complement(1226578..1229430) 1 NC_011751.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1229430 torS 7158512 torS Escherichia coli UMN026 hybrid sensory histidine kinase TorS YP_002411928.1 1226578 R 585056 CDS YP_002411929.1 218704410 7158093 1229393..1230421 1 NC_011751.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1230421 torT 7158093 torT Escherichia coli UMN026 TMAO reductase system periplasmic protein TorT YP_002411929.1 1229393 D 585056 CDS YP_002411930.1 218704411 7158094 complement(1230394..1231086) 1 NC_011751.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1231086 torR 7158094 torR Escherichia coli UMN026 DNA-binding transcriptional regulator TorR YP_002411930.1 1230394 R 585056 CDS YP_002411931.1 218704412 7158092 1231216..1232388 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1232388 torC 7158092 torC Escherichia coli UMN026 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit YP_002411931.1 1231216 D 585056 CDS YP_002411932.1 218704413 7158090 1232388..1234934 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1234934 torA 7158090 torA Escherichia coli UMN026 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit YP_002411932.1 1232388 D 585056 CDS YP_002411933.1 218704414 7158089 1234931..1235530 1 NC_011751.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1235530 torD 7158089 torD Escherichia coli UMN026 chaperone protein TorD YP_002411933.1 1234931 D 585056 CDS YP_002411934.1 218704415 7158091 complement(1235623..1235928) 1 NC_011751.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1235928 cbpM 7158091 cbpM Escherichia coli UMN026 chaperone-modulator protein CbpM YP_002411934.1 1235623 R 585056 CDS YP_002411935.1 218704416 7155923 complement(1235928..1236848) 1 NC_011751.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1236848 cbpA 7155923 cbpA Escherichia coli UMN026 curved DNA-binding protein CbpA YP_002411935.1 1235928 R 585056 CDS YP_002411936.1 218704417 7155922 1237108..1238364 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8302830; hypothetical protein 1238364 yccE 7155922 yccE Escherichia coli UMN026 hypothetical protein YP_002411936.1 1237108 D 585056 CDS YP_002411937.1 218704418 7158509 1238657..1239898 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12455612, 90368616, 91297199, 2153660, 9298646; Product type e : enzyme; glucose-1-phosphatase/inositol phosphatase 1239898 agp 7158509 agp Escherichia coli UMN026 glucose-1-phosphatase/inositol phosphatase YP_002411937.1 1238657 D 585056 CDS YP_002411938.1 218704419 7155716 complement(1239936..1240163) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1240163 yccJ 7155716 yccJ Escherichia coli UMN026 hypothetical protein YP_002411938.1 1239936 R 585056 CDS YP_002411939.1 218704420 7158511 complement(1240184..1240780) 1 NC_011751.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1240780 wrbA 7158511 wrbA Escherichia coli UMN026 TrpR binding protein WrbA YP_002411939.1 1240184 R 585056 CDS YP_002411940.1 218704421 7158234 1240984..1241220 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1241220 7158234 ECUMN_1187 Escherichia coli UMN026 hypothetical protein YP_002411940.1 1240984 D 585056 CDS YP_002411941.1 218704422 7154856 1241153..1241326 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1241326 ymdF 7154856 ymdF Escherichia coli UMN026 hypothetical protein YP_002411941.1 1241153 D 585056 CDS YP_002411942.1 218704423 7159477 complement(1241415..1242851) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type t : transporter; pyrimidine transporter 1242851 rutG 7159477 rutG Escherichia coli UMN026 pyrimidine transporter YP_002411942.1 1241415 R 585056 CDS YP_002411943.1 218704424 7157828 complement(1242758..1243252) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542, 10633095; Product type e : enzyme; flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway 1243252 rutF 7157828 rutF Escherichia coli UMN026 flavin:NADH oxidoreductase subunit of alternative pyrimidine degradation pathway YP_002411943.1 1242758 R 585056 CDS YP_002411944.1 218704425 7157827 complement(1243263..1243853) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; hypothetical protein 1243853 rutE 7157827 rutE Escherichia coli UMN026 hypothetical protein YP_002411944.1 1243263 R 585056 CDS YP_002411945.1 218704426 7157826 complement(1243850..1244689) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein 1244689 rutD 7157826 rutD Escherichia coli UMN026 alternative pyrimidine degradation pathway protein YP_002411945.1 1243850 R 585056 CDS YP_002411946.1 218704427 7157825 complement(1244670..1245056) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein 1245056 rutC 7157825 rutC Escherichia coli UMN026 alternative pyrimidine degradation pathway protein YP_002411946.1 1244670 R 585056 CDS YP_002411947.1 218704428 7157824 complement(1245068..1245760) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; alternative pyrimidine degradation pathway protein 1245760 rutB 7157824 rutB Escherichia coli UMN026 alternative pyrimidine degradation pathway protein YP_002411947.1 1245068 R 585056 CDS YP_002411948.1 218704429 7157823 complement(1245760..1246908) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme; monooxygenase of the alternative pyrimidine degradation pathway 1246908 rutA 7157823 rutA Escherichia coli UMN026 monooxygenase of the alternative pyrimidine degradation pathway YP_002411948.1 1245760 R 585056 CDS YP_002411949.1 218704430 7157822 1247139..1247777 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator; DNA-binding transcriptional regulator 1247777 rutR 7157822 rutR Escherichia coli UMN026 DNA-binding transcriptional regulator YP_002411949.1 1247139 D 585056 CDS YP_002411950.1 218704431 7157829 complement(1247817..1251779) 1 NC_011751.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1251779 putA 7157829 putA Escherichia coli UMN026 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002411950.1 1247817 R 585056 CDS YP_002411951.1 218704432 7157586 1252202..1253710 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter; proline:sodium symporter 1253710 putP 7157586 putP Escherichia coli UMN026 proline:sodium symporter YP_002411951.1 1252202 D 585056 CDS YP_002411952.1 218704433 7157587 complement(1253858..1255201) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1255201 7157587 ECUMN_1199 Escherichia coli UMN026 hypothetical protein YP_002411952.1 1253858 R 585056 CDS YP_002411953.1 218704434 7154857 complement(1256210..1256356) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1256356 7154857 ECUMN_1200 Escherichia coli UMN026 hypothetical protein YP_002411953.1 1256210 R 585056 CDS YP_002411954.1 218704435 7154858 1256383..1257222 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ferrous iron permease 1257222 efeU 7154858 efeU Escherichia coli UMN026 ferrous iron permease YP_002411954.1 1256383 D 585056 CDS YP_002411955.1 218704436 7156230 1257280..1258407 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter; hypothetical protein 1258407 efeO 7156230 efeO Escherichia coli UMN026 hypothetical protein YP_002411955.1 1257280 D 585056 CDS YP_002411956.1 218704437 7156229 1258413..1259684 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter; iron transport heme-binding periplasmic protein 1259684 efeB 7156229 efeB Escherichia coli UMN026 iron transport heme-binding periplasmic protein YP_002411956.1 1258413 D 585056 CDS YP_002411957.1 218704438 7156228 complement(1259799..1259954) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1259954 7156228 ECUMN_1204 Escherichia coli UMN026 hypothetical protein YP_002411957.1 1259799 R 585056 CDS YP_002411958.1 218704439 7154859 1260034..1261098 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : putative enzyme; hypothetical protein 1261098 phoH 7154859 phoH Escherichia coli UMN026 hypothetical protein YP_002411958.1 1260034 D 585056 CDS YP_002411959.1 218704440 7157458 1261685..1262371 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1262371 7157458 ECUMN_1206 Escherichia coli UMN026 hypothetical protein YP_002411959.1 1261685 D 585056 CDS YP_002411960.1 218704441 7155641 1262786..1263724 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme; 2-ketoacid reductase 1263724 ycdW 7155641 ycdW Escherichia coli UMN026 2-ketoacid reductase YP_002411960.1 1262786 D 585056 CDS YP_002411961.1 218704442 7158520 1263779..1264516 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : putative enzyme; putative hydrolase 1264516 ycdX 7158520 ycdX Escherichia coli UMN026 putative hydrolase YP_002411961.1 1263779 D 585056 CDS YP_002411962.1 218704443 7158521 1264540..1265094 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1265094 ycdY 7158521 ycdY Escherichia coli UMN026 hypothetical protein YP_002411962.1 1264540 D 585056 CDS YP_002411963.1 218704444 7158522 1265196..1265687 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1265687 ycdZ 7158522 ycdZ Escherichia coli UMN026 hypothetical protein YP_002411963.1 1265196 D 585056 CDS YP_002411964.1 218704445 7158523 complement(1265751..1266584) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein; putative outer membrane lipoprotein involved in curli production assembly/transport 1266584 csgG 7158523 csgG Escherichia coli UMN026 putative outer membrane lipoprotein involved in curli production assembly/transport YP_002411964.1 1265751 R 585056 CDS YP_002411965.1 218704446 7156031 complement(1266611..1267027) 1 NC_011751.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1267027 csgF 7156031 csgF Escherichia coli UMN026 curli assembly protein CsgF YP_002411965.1 1266611 R 585056 CDS YP_002411966.1 218704447 7156030 complement(1267052..1267441) 1 NC_011751.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1267441 csgE 7156030 csgE Escherichia coli UMN026 curli assembly protein CsgE YP_002411966.1 1267052 R 585056 CDS YP_002411967.1 218704448 7156029 complement(1267446..1268096) 1 NC_011751.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1268096 csgD 7156029 csgD Escherichia coli UMN026 DNA-binding transcriptional regulator CsgD YP_002411967.1 1267446 R 585056 CDS YP_002411968.1 218704449 7156028 1268851..1269306 1 NC_011751.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1269306 csgB 7156028 csgB Escherichia coli UMN026 curlin minor subunit YP_002411968.1 1268851 D 585056 CDS YP_002411969.1 218704450 7156026 1269347..1269802 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure; cryptic curlin major subunit 1269802 csgA 7156026 csgA Escherichia coli UMN026 cryptic curlin major subunit YP_002411969.1 1269347 D 585056 CDS YP_002411970.1 218704451 7156025 1269702..1270193 1 NC_011751.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1270193 csgC 7156025 csgC Escherichia coli UMN026 putative autoagglutination protein YP_002411970.1 1269702 D 585056 CDS YP_002411971.1 218704452 7156027 1270314..1270625 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1270625 ymdA 7156027 ymdA Escherichia coli UMN026 hypothetical protein YP_002411971.1 1270314 D 585056 CDS YP_002411972.1 218704453 7159474 1270720..1271253 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1271253 ymdB 7159474 ymdB Escherichia coli UMN026 hypothetical protein YP_002411972.1 1270720 D 585056 CDS YP_002411973.1 218704454 7159475 1271255..1272676 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 1272676 ymdC 7159475 ymdC Escherichia coli UMN026 putative hydrolase YP_002411973.1 1271255 D 585056 CDS YP_002411974.1 218704455 7159476 complement(1272684..1273841) 1 NC_011751.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1273841 mdoC 7159476 mdoC Escherichia coli UMN026 glucans biosynthesis protein YP_002411974.1 1272684 R 585056 CDS YP_002411975.1 218704456 7157073 complement(1273886..1274029) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1274029 7157073 ECUMN_1222 Escherichia coli UMN026 hypothetical protein YP_002411975.1 1273886 R 585056 CDS YP_002411976.1 218704457 7154861 complement(1274033..1274191) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1274191 7154861 ECUMN_1223 Escherichia coli UMN026 hypothetical protein YP_002411976.1 1274033 R 585056 CDS YP_002411977.1 218704458 7154862 1274235..1275770 1 NC_011751.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1275770 mdoG 7154862 mdoG Escherichia coli UMN026 glucan biosynthesis protein G YP_002411977.1 1274235 D 585056 CDS YP_002411978.1 218704459 7157075 1275763..1278306 1 NC_011751.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1278306 mdoH 7157075 mdoH Escherichia coli UMN026 glucosyltransferase MdoH YP_002411978.1 1275763 D 585056 CDS YP_002411979.1 218704460 7157076 1278479..1278706 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1278706 yceK 7157076 yceK Escherichia coli UMN026 hypothetical protein YP_002411979.1 1278479 D 585056 CDS YP_002411980.1 218704461 7158532 complement(1278707..1279081) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719; hypothetical protein 1279081 msyB 7158532 msyB Escherichia coli UMN026 hypothetical protein YP_002411980.1 1278707 R 585056 CDS YP_002411981.1 218704462 7157189 complement(1279164..1280390) 1 NC_011751.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1280390 mdtG 7157189 mdtG Escherichia coli UMN026 drug efflux system protein MdtG YP_002411981.1 1279164 R 585056 CDS YP_002411982.1 218704463 7157083 complement(1280562..1281482) 1 NC_011751.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1281482 lpxL 7157083 lpxL Escherichia coli UMN026 lipid A biosynthesis lauroyl acyltransferase YP_002411982.1 1280562 R 585056 CDS YP_002411983.1 218704464 7157015 1281707..1282759 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644; hypothetical protein 1282759 yceA 7157015 yceA Escherichia coli UMN026 hypothetical protein YP_002411983.1 1281707 D 585056 CDS YP_002411984.1 218704465 7158524 complement(1282801..1283376) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier; hypothetical protein 1283376 yceI 7158524 yceI Escherichia coli UMN026 hypothetical protein YP_002411984.1 1282801 R 585056 CDS YP_002411985.1 218704466 7158530 complement(1283380..1283946) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome b561 1283946 yceJ 7158530 yceJ Escherichia coli UMN026 putative cytochrome b561 YP_002411985.1 1283380 R 585056 CDS YP_002411986.1 218704467 7158531 complement(1284368..1285486) 1 NC_011751.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1285486 solA 7158531 solA Escherichia coli UMN026 N-methyltryptophan oxidase YP_002411986.1 1284368 R 585056 CDS YP_002411987.1 218704468 7157952 complement(1285601..1285855) 1 NC_011751.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1285855 bssS 7157952 bssS Escherichia coli UMN026 biofilm formation regulatory protein BssS YP_002411987.1 1285601 R 585056 CDS YP_002411988.1 218704469 7155893 complement(1286145..1286390) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9606202, 11152126, 11230150, 8682790; Product type f : factor; DNA damage-inducible protein I 1286390 dinI 7155893 dinI Escherichia coli UMN026 DNA damage-inducible protein I YP_002411988.1 1286145 R 585056 CDS YP_002411989.1 218704470 7156170 complement(1286464..1287510) 1 NC_011751.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1287510 pyrC 7156170 pyrC Escherichia coli UMN026 dihydroorotase YP_002411989.1 1286464 R 585056 CDS YP_002411990.1 218704471 7157598 complement(1287616..1288176) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1288176 yceB 7157598 yceB Escherichia coli UMN026 hypothetical protein YP_002411990.1 1287616 R 585056 CDS YP_002411991.1 218704472 7158525 complement(1288310..1288957) 1 NC_011751.1 cofactor involved in the reduction of disulfides; glutaredoxin 2 1288957 grxB 7158525 grxB Escherichia coli UMN026 glutaredoxin 2 YP_002411991.1 1288310 R 585056 CDS YP_002411992.1 218704473 7156615 complement(1289021..1290229) 1 NC_011751.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1290229 mdtH 7156615 mdtH Escherichia coli UMN026 multidrug resistance protein MdtH YP_002411992.1 1289021 R 585056 CDS YP_002411993.1 218704474 7157084 1290465..1291049 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme; ribosomal-protein-S5-alanine N-acetyltransferase 1291049 rimJ 7157084 rimJ Escherichia coli UMN026 ribosomal-protein-S5-alanine N-acetyltransferase YP_002411993.1 1290465 D 585056 CDS YP_002411994.1 218704475 7157692 1291060..1291707 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880; hypothetical protein 1291707 yceH 7157692 yceH Escherichia coli UMN026 hypothetical protein YP_002411994.1 1291060 D 585056 CDS YP_002411995.1 218704476 7158529 1291709..1292632 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1292632 mviM 7158529 mviM Escherichia coli UMN026 putative oxidoreductase YP_002411995.1 1291709 D 585056 CDS YP_002411996.1 218704477 7157217 1292742..1294277 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1294277 mviN 7157217 mviN Escherichia coli UMN026 hypothetical protein YP_002411996.1 1292742 D 585056 CDS YP_002411997.1 218704478 7157218 complement(1294317..1294733) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10320579; Product type f : factor; export chaperone for FlgK and FlgL 1294733 flgN 7157218 flgN Escherichia coli UMN026 export chaperone for FlgK and FlgL YP_002411997.1 1294317 R 585056 CDS YP_002411998.1 218704479 7156390 complement(1294738..1295031) 1 NC_011751.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 1295031 flgM 7156390 flgM Escherichia coli UMN026 anti-sigma28 factor FlgM YP_002411998.1 1294738 R 585056 CDS YP_002411999.1 218704480 7156389 complement(1295107..1295766) 1 NC_011751.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1295766 flgA 7156389 flgA Escherichia coli UMN026 flagellar basal body P-ring biosynthesis protein FlgA YP_002411999.1 1295107 R 585056 CDS YP_002412000.1 218704481 7156377 1295921..1296337 1 NC_011751.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1296337 flgB 7156377 flgB Escherichia coli UMN026 flagellar basal body rod protein FlgB YP_002412000.1 1295921 D 585056 CDS YP_002412001.1 218704482 7156378 1296341..1296745 1 NC_011751.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1296745 flgC 7156378 flgC Escherichia coli UMN026 flagellar basal body rod protein FlgC YP_002412001.1 1296341 D 585056 CDS YP_002412002.1 218704483 7156379 1296757..1297452 1 NC_011751.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1297452 flgD 7156379 flgD Escherichia coli UMN026 flagellar basal body rod modification protein YP_002412002.1 1296757 D 585056 CDS YP_002412003.1 218704484 7156380 1297477..1298682 1 NC_011751.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1298682 flgE 7156380 flgE Escherichia coli UMN026 flagellar hook protein FlgE YP_002412003.1 1297477 D 585056 CDS YP_002412004.1 218704485 7156381 1298702..1299457 1 NC_011751.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1299457 flgF 7156381 flgF Escherichia coli UMN026 flagellar basal body rod protein FlgF YP_002412004.1 1298702 D 585056 CDS YP_002412005.1 218704486 7156382 1299594..1300376 1 NC_011751.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1300376 flgG 7156382 flgG Escherichia coli UMN026 flagellar basal body rod protein FlgG YP_002412005.1 1299594 D 585056 CDS YP_002412006.1 218704487 7156383 1300429..1301127 1 NC_011751.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1301127 flgH 7156383 flgH Escherichia coli UMN026 flagellar basal body L-ring protein YP_002412006.1 1300429 D 585056 CDS YP_002412007.1 218704488 7156384 1301139..1302236 1 NC_011751.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1302236 flgI 7156384 flgI Escherichia coli UMN026 flagellar basal body P-ring protein YP_002412007.1 1301139 D 585056 CDS YP_002412008.1 218704489 7156385 1302236..1303177 1 NC_011751.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1303177 flgJ 7156385 flgJ Escherichia coli UMN026 flagellar rod assembly protein/muramidase FlgJ YP_002412008.1 1302236 D 585056 CDS YP_002412009.1 218704490 7156386 1303243..1304886 1 NC_011751.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1304886 flgK 7156386 flgK Escherichia coli UMN026 flagellar hook-associated protein FlgK YP_002412009.1 1303243 D 585056 CDS YP_002412010.1 218704491 7156387 1304898..1305851 1 NC_011751.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1305851 flgL 7156387 flgL Escherichia coli UMN026 flagellar hook-associated protein FlgL YP_002412010.1 1304898 D 585056 CDS YP_002412011.1 218704492 7156388 complement(1305946..1306455) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1306455 7156388 ECUMN_1258 Escherichia coli UMN026 hypothetical protein YP_002412011.1 1305946 R 585056 CDS YP_002412012.1 218704493 7154863 complement(1306437..1306775) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1306775 7154863 ECUMN_1259 Escherichia coli UMN026 hypothetical protein YP_002412012.1 1306437 R 585056 CDS YP_002412013.1 218704494 7154864 complement(1306863..1310048) 1 NC_011751.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1310048 rne 7154864 rne Escherichia coli UMN026 ribonuclease E YP_002412013.1 1306863 R 585056 CDS YP_002412014.1 218704495 7157711 1310621..1311580 1 NC_011751.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1311580 rluC 7157711 rluC Escherichia coli UMN026 23S rRNA pseudouridylate synthase C YP_002412014.1 1310621 D 585056 CDS YP_002412015.1 218704496 7157701 complement(1311692..1312276) 1 NC_011751.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1312276 yceF 7157701 yceF Escherichia coli UMN026 Maf-like protein YP_002412015.1 1311692 R 585056 CDS YP_002412016.1 218704497 7157970 1312475..1312996 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160; hypothetical protein 1312996 yceD 7157970 yceD Escherichia coli UMN026 hypothetical protein YP_002412016.1 1312475 D 585056 CDS YP_002412017.1 218704498 7158526 1313048..1313221 1 NC_011751.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1313221 rpmF 7158526 rpmF Escherichia coli UMN026 50S ribosomal protein L32 YP_002412017.1 1313048 D 585056 CDS YP_002412018.1 218704499 7157753 1313302..1314372 1 NC_011751.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1314372 plsX 7157753 plsX Escherichia coli UMN026 putative glycerol-3-phosphate acyltransferase PlsX YP_002412018.1 1313302 D 585056 CDS YP_002412019.1 218704500 7157474 1314440..1315393 1 NC_011751.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III 1315393 fabH 7157474 fabH Escherichia coli UMN026 3-oxoacyl-(acyl carrier protein) synthase III YP_002412019.1 1314440 D 585056 CDS YP_002412020.1 218704501 7156298 1315409..1316338 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme; malonyl-CoA-[acyl-carrier-protein] transacylase 1316338 fabD 7156298 fabD Escherichia coli UMN026 malonyl-CoA-[acyl-carrier-protein] transacylase YP_002412020.1 1315409 D 585056 CDS YP_002412021.1 218704502 7156295 1316351..1317085 1 NC_011751.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 1317085 fabG 7156295 fabG Escherichia coli UMN026 3-ketoacyl-(acyl-carrier-protein) reductase YP_002412021.1 1316351 D 585056 CDS YP_002412022.1 218704503 7156297 1317296..1317532 1 NC_011751.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1317532 acpP 7156297 acpP Escherichia coli UMN026 acyl carrier protein YP_002412022.1 1317296 D 585056 CDS YP_002412023.1 218704504 7155684 1317620..1318861 1 NC_011751.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1318861 fabF 7155684 fabF Escherichia coli UMN026 3-oxoacyl-(acyl carrier protein) synthase II YP_002412023.1 1317620 D 585056 CDS YP_002412024.1 218704505 7156296 1318910..1319098 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1319098 7156296 ECUMN_1271 Escherichia coli UMN026 hypothetical protein YP_002412024.1 1318910 D 585056 CDS YP_002412025.1 218704506 7154865 1319004..1319513 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 1319513 7154865 ECUMN_1272 Escherichia coli UMN026 transposase IS605 family, IS200 group YP_002412025.1 1319004 D 585056 CDS YP_002412026.1 218704507 7154866 1319693..1320502 1 NC_011751.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1320502 pabC 7154866 pabC Escherichia coli UMN026 4-amino-4-deoxychorismate lyase YP_002412026.1 1319693 D 585056 CDS YP_002412027.1 218704508 7157375 1320505..1321527 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 1321527 yceG 7157375 yceG Escherichia coli UMN026 hypothetical protein YP_002412027.1 1320505 D 585056 CDS YP_002412028.1 218704509 7158528 1321517..1322158 1 NC_011751.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1322158 tmk 7158528 tmk Escherichia coli UMN026 thymidylate kinase YP_002412028.1 1321517 D 585056 CDS YP_002412029.1 218704510 7158077 1322155..1323159 1 NC_011751.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1323159 holB 7158077 holB Escherichia coli UMN026 DNA polymerase III subunit delta' YP_002412029.1 1322155 D 585056 CDS YP_002412030.1 218704511 7156697 1323170..1323967 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : putative enzyme; putative metallodependent hydrolase 1323967 ycfH 7156697 ycfH Escherichia coli UMN026 putative metallodependent hydrolase YP_002412030.1 1323170 D 585056 CDS YP_002412031.1 218704512 7158534 1324262..1325695 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1325695 ptsG 7158534 ptsG Escherichia coli UMN026 PTS system glucose-specific transporter subunits IIBC YP_002412031.1 1324262 D 585056 CDS YP_002412032.1 218704513 7157566 complement(1325755..1327944) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90286919, 3032906, 10529396; Product type t : transporter; ferric-rhodotorulic acid outer membrane transporter 1327944 fhuE 7157566 fhuE Escherichia coli UMN026 ferric-rhodotorulic acid outer membrane transporter YP_002412032.1 1325755 R 585056 CDS YP_002412033.1 218704514 7156348 1328278..1328637 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme; purine nucleoside phosphoramidase 1328637 hinT 7156348 hinT Escherichia coli UMN026 purine nucleoside phosphoramidase YP_002412033.1 1328278 D 585056 CDS YP_002412034.1 218704515 7156670 1328640..1329017 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1329017 ycfL 7156670 ycfL Escherichia coli UMN026 hypothetical protein YP_002412034.1 1328640 D 585056 CDS YP_002412035.1 218704516 7158536 1329031..1329672 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 1329672 ycfM 7158536 ycfM Escherichia coli UMN026 putative outer membrane lipoprotein YP_002412035.1 1329031 D 585056 CDS YP_002412036.1 218704517 7158537 1329653..1330477 1 NC_011751.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1330477 thiK 7158537 thiK Escherichia coli UMN026 thiamine kinase YP_002412036.1 1329653 D 585056 CDS YP_002412037.1 218704518 7158538 1330488..1331513 1 NC_011751.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1331513 nagZ 7158538 nagZ Escherichia coli UMN026 beta-hexosaminidase YP_002412037.1 1330488 D 585056 CDS YP_002412038.1 218704519 7157232 1331536..1332078 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1332078 ycfP 7157232 ycfP Escherichia coli UMN026 hypothetical protein YP_002412038.1 1331536 D 585056 CDS YP_002412039.1 218704520 7158539 1332478..1333782 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme; respiratory NADH dehydrogenase 2/cupric reductase 1333782 ndh 7158539 ndh Escherichia coli UMN026 respiratory NADH dehydrogenase 2/cupric reductase YP_002412039.1 1332478 D 585056 CDS YP_002412040.1 218704521 7157261 1334009..1334548 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428; hypothetical protein 1334548 ycfJ 7157261 ycfJ Escherichia coli UMN026 hypothetical protein YP_002412040.1 1334009 D 585056 CDS YP_002412041.1 218704522 7158535 complement(1334610..1335242) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1335242 ycfQ 7158535 ycfQ Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412041.1 1334610 R 585056 CDS YP_002412042.1 218704523 7158540 1335483..1335740 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; hypothetical protein 1335740 ycfR 7158540 ycfR Escherichia coli UMN026 hypothetical protein YP_002412042.1 1335483 D 585056 CDS YP_002412043.1 218704524 7158541 complement(1335823..1336785) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1336785 ycfS 7158541 ycfS Escherichia coli UMN026 hypothetical protein YP_002412043.1 1335823 R 585056 CDS YP_002412044.1 218704525 7158542 complement(1336930..1340376) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor; transcription-repair coupling factor 1340376 mfd 7158542 mfd Escherichia coli UMN026 transcription-repair coupling factor YP_002412044.1 1336930 R 585056 CDS YP_002412045.1 218704526 7157114 complement(1340504..1341577) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1341577 ycfT 7157114 ycfT Escherichia coli UMN026 hypothetical protein YP_002412045.1 1340504 R 585056 CDS YP_002412046.1 218704527 7158543 1341838..1343037 1 NC_011751.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1343037 lolC 7158543 lolC Escherichia coli UMN026 outer membrane-specific lipoprotein transporter subunit LolC YP_002412046.1 1341838 D 585056 CDS YP_002412047.1 218704528 7156996 1343030..1343731 1 NC_011751.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1343731 lolD 7156996 lolD Escherichia coli UMN026 lipoprotein transporter ATP-binding subunit YP_002412047.1 1343030 D 585056 CDS YP_002412048.1 218704529 7156997 1343731..1344975 1 NC_011751.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1344975 lolE 7156997 lolE Escherichia coli UMN026 outer membrane-specific lipoprotein transporter subunit LolE YP_002412048.1 1343731 D 585056 CDS YP_002412049.1 218704530 7156998 1345004..1345915 1 NC_011751.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1345915 ycfX 7156998 ycfX Escherichia coli UMN026 N-acetyl-D-glucosamine kinase YP_002412049.1 1345004 D 585056 CDS YP_002412050.1 218704531 7158544 1345931..1346752 1 NC_011751.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1346752 cobB 7158544 cobB Escherichia coli UMN026 NAD-dependent deacetylase YP_002412050.1 1345931 D 585056 CDS YP_002412051.1 218704532 7155991 complement(1346890..1347675) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1347675 ycfZ 7155991 ycfZ Escherichia coli UMN026 hypothetical protein YP_002412051.1 1346890 R 585056 CDS YP_002412052.1 218704533 7158545 complement(1347672..1348133) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1348133 ymfA 7158545 ymfA Escherichia coli UMN026 hypothetical protein YP_002412052.1 1347672 R 585056 CDS YP_002412053.1 218704534 7159478 complement(1348191..1349237) 1 NC_011751.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein 1349237 potD 7159478 potD Escherichia coli UMN026 spermidine/putrescine ABC transporter periplasmic substrate-binding protein YP_002412053.1 1348191 R 585056 CDS YP_002412054.1 218704535 7157490 complement(1349234..1350028) 1 NC_011751.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1350028 potC 7157490 potC Escherichia coli UMN026 spermidine/putrescine ABC transporter membrane protein YP_002412054.1 1349234 R 585056 CDS YP_002412055.1 218704536 7157489 complement(1350195..1351313) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Integrase from bacteriophage origin 1351313 int 7157489 int Escherichia coli UMN026 Integrase from bacteriophage origin YP_002412055.1 1350195 R 585056 CDS YP_002412056.1 218704537 7156840 complement(1351282..1351560) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative excisionase for bacteriophage origin 1351560 7156840 ECUMN_1304 Escherichia coli UMN026 putative excisionase for bacteriophage origin YP_002412056.1 1351282 R 585056 CDS YP_002412057.1 218704538 7154867 complement(1351613..1354069) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2199308; Product type h : extrachromosomal origin; Exodeoxyribonuclease VIII from bacteriophage origin 1354069 7154867 ECUMN_1305 Escherichia coli UMN026 Exodeoxyribonuclease VIII from bacteriophage origin YP_002412057.1 1351613 R 585056 CDS YP_002412058.1 218704539 7154868 complement(1354147..1354350) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1354350 7154868 ECUMN_1306 Escherichia coli UMN026 hypothetical protein YP_002412058.1 1354147 R 585056 CDS YP_002412059.1 218704540 7154869 complement(1354347..1354535) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3041373; Product type h : extrachromosomal origin; Cell division inhibition protein dicB from bacteriophage origin 1354535 dicB 7154869 dicB Escherichia coli UMN026 Cell division inhibition protein dicB from bacteriophage origin YP_002412059.1 1354347 R 585056 CDS YP_002412060.1 218704541 7156163 complement(1354546..1355400) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1355400 7156163 ECUMN_1308 Escherichia coli UMN026 hypothetical protein YP_002412060.1 1354546 R 585056 CDS YP_002412061.1 218704542 7154870 complement(1355931..1356317) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1356317 7154870 ECUMN_1309 Escherichia coli UMN026 hypothetical protein YP_002412061.1 1355931 R 585056 CDS YP_002412062.1 218704543 7158644 complement(1356676..1357083) 1 NC_011751.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1357083 dicA 7158644 dicA Escherichia coli UMN026 transcriptional repressor DicA YP_002412062.1 1356676 R 585056 CDS YP_002412063.1 218704544 7156161 1357160..1357387 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88232418, 3532030; Product type h : extrachromosomal origin; DNA-binding transcriptional regulator DicC 1357387 dicC 7156161 dicC Escherichia coli UMN026 DNA-binding transcriptional regulator DicC YP_002412063.1 1357160 D 585056 CDS YP_002412064.1 218704545 7156164 1357371..1357922 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1357922 7156164 ECUMN_1313 Escherichia coli UMN026 hypothetical protein YP_002412064.1 1357371 D 585056 CDS YP_002412065.1 218704546 7154872 1357819..1358934 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1358934 7154872 ECUMN_1314 Escherichia coli UMN026 hypothetical protein YP_002412065.1 1357819 D 585056 CDS YP_002412066.1 218704547 7154873 1358927..1359388 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1359388 7154873 ECUMN_1315 Escherichia coli UMN026 hypothetical protein YP_002412066.1 1358927 D 585056 CDS YP_002412067.1 218704548 7154874 1359404..1360192 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360192 7154874 ECUMN_1316 Escherichia coli UMN026 hypothetical protein YP_002412067.1 1359404 D 585056 CDS YP_002412068.1 218704549 7154875 1360193..1360600 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360600 7154875 ECUMN_1317 Escherichia coli UMN026 hypothetical protein YP_002412068.1 1360193 D 585056 CDS YP_002412069.1 218704550 7154876 1360597..1360893 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1360893 7154876 ECUMN_1318 Escherichia coli UMN026 hypothetical protein YP_002412069.1 1360597 D 585056 CDS YP_002412070.1 218704551 7154877 1360890..1361351 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1361351 7154877 ECUMN_1319 Escherichia coli UMN026 hypothetical protein YP_002412070.1 1360890 D 585056 CDS YP_002412071.1 218704552 7154878 1361329..1361685 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1361685 7154878 ECUMN_1320 Escherichia coli UMN026 hypothetical protein YP_002412071.1 1361329 D 585056 CDS YP_002412072.1 218704553 7154879 1361781..1362188 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1362188 7154879 ECUMN_1321 Escherichia coli UMN026 hypothetical protein YP_002412072.1 1361781 D 585056 CDS YP_002412073.1 218704554 7154880 1362190..1362555 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative HNH endonuclease from bacteriophage origin 1362555 7154880 ECUMN_1322 Escherichia coli UMN026 putative HNH endonuclease from bacteriophage origin YP_002412073.1 1362190 D 585056 CDS YP_002412074.1 218704555 7154881 1362552..1363538 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1363538 7154881 ECUMN_1323 Escherichia coli UMN026 hypothetical protein YP_002412074.1 1362552 D 585056 CDS YP_002412075.1 218704556 7154882 1364469..1364720 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2990907; Product type h : extrachromosomal origin; hypothetical protein 1364720 rem 7154882 rem Escherichia coli UMN026 hypothetical protein YP_002412075.1 1364469 D 585056 CDS YP_002412076.1 218704557 7157650 1364787..1365065 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1365065 7157650 ECUMN_1325 Escherichia coli UMN026 hypothetical protein YP_002412076.1 1364787 D 585056 CDS YP_002412077.1 218704558 7154883 1365067..1366125 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1366125 ydfU 7154883 ydfU Escherichia coli UMN026 hypothetical protein YP_002412077.1 1365067 D 585056 CDS YP_002412078.1 218704559 7158656 1366126..1366494 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative crossover junction endodeoxyribonuclease rusA 1366494 7158656 ECUMN_1327 Escherichia coli UMN026 putative crossover junction endodeoxyribonuclease rusA YP_002412078.1 1366126 D 585056 CDS YP_002412079.1 218704560 7154884 1366481..1367176 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Antitermination protein Q 1367176 Q 7154884 Q Escherichia coli UMN026 Antitermination protein Q YP_002412079.1 1366481 D 585056 CDS YP_002412080.1 218704561 7157608 1367254..1367586 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1367586 7157608 ECUMN_1329 Escherichia coli UMN026 hypothetical protein YP_002412080.1 1367254 D 585056 CDS YP_002412081.1 218704562 7154885 1367528..1367824 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1367824 7154885 ECUMN_1330 Escherichia coli UMN026 hypothetical protein YP_002412081.1 1367528 D 585056 CDS YP_002412082.1 218704563 7154887 1368737..1368898 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1368898 7154887 ECUMN_1332 Escherichia coli UMN026 hypothetical protein YP_002412082.1 1368737 D 585056 CDS YP_002412083.1 218704564 7154888 1369048..1369263 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 1369263 essD 7154888 essD Escherichia coli UMN026 putative phage lysis protein S; DLP12 prophage YP_002412083.1 1369048 D 585056 CDS YP_002412084.1 218704565 7156270 1369265..1370158 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1370158 7156270 ECUMN_1334 Escherichia coli UMN026 hypothetical protein YP_002412084.1 1369265 D 585056 CDS YP_002412085.1 218704566 7154889 1370195..1370728 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated lysozyme; Qin prophage 1370728 ydfQ 7154889 ydfQ Escherichia coli UMN026 putative membrane-associated lysozyme; Qin prophage YP_002412085.1 1370195 D 585056 CDS YP_002412086.1 218704567 7158652 1370852..1371067 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1371067 7158652 ECUMN_1336 Escherichia coli UMN026 hypothetical protein YP_002412086.1 1370852 D 585056 CDS YP_002412087.1 218704568 7154890 1371210..1371683 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Endopeptidase from bacteriophage origin 1371683 rz 7154890 rz Escherichia coli UMN026 Endopeptidase from bacteriophage origin YP_002412087.1 1371210 D 585056 CDS YP_002412088.1 218704569 7157861 1371940..1372320 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tonB-like membrane protein encoded within prophage 1372320 7157861 ECUMN_1338 Escherichia coli UMN026 putative tonB-like membrane protein encoded within prophage YP_002412088.1 1371940 D 585056 CDS YP_002412089.1 218704570 7154891 complement(1372443..1372796) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1372796 7154891 ECUMN_1339 Escherichia coli UMN026 hypothetical protein YP_002412089.1 1372443 R 585056 CDS YP_002412090.1 218704571 7154893 complement(1372684..1373004) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1373004 7154893 ECUMN_1341 Escherichia coli UMN026 hypothetical protein YP_002412090.1 1372684 R 585056 CDS YP_002412091.1 218704572 7154894 1373279..1373788 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Terminase small subunit (DNA packaging protein Nu1) from bacteriophage origin 1373788 7154894 ECUMN_1342 Escherichia coli UMN026 putative Terminase small subunit (DNA packaging protein Nu1) from bacteriophage origin YP_002412091.1 1373279 D 585056 CDS YP_002412092.1 218704573 7154895 1373790..1375688 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Terminase large subunit (Gp2) 1375688 7154895 ECUMN_1343 Escherichia coli UMN026 Terminase large subunit (Gp2) YP_002412092.1 1373790 D 585056 CDS YP_002412093.1 218704574 7154896 1375672..1375878 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head stabilization protein (Head protein GP3) 1375878 7154896 ECUMN_1344 Escherichia coli UMN026 Head stabilization protein (Head protein GP3) YP_002412093.1 1375672 D 585056 CDS YP_002412094.1 218704575 7154897 1375875..1377467 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; portal protein (Head protein GP4) 1377467 7154897 ECUMN_1345 Escherichia coli UMN026 portal protein (Head protein GP4) YP_002412094.1 1375875 D 585056 CDS YP_002412095.1 218704576 7154898 1377457..1378905 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head-tail preconnector protein GP5 1378905 7154898 ECUMN_1346 Escherichia coli UMN026 Head-tail preconnector protein GP5 YP_002412095.1 1377457 D 585056 CDS YP_002412096.1 218704577 7154899 1378942..1379289 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Head decoration protein (Head protein GPshp) 1379289 7154899 ECUMN_1347 Escherichia coli UMN026 Head decoration protein (Head protein GPshp) YP_002412096.1 1378942 D 585056 CDS YP_002412097.1 218704578 7154900 1379347..1380375 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major head protein (Head protein gp7) 1380375 7154900 ECUMN_1348 Escherichia coli UMN026 Major head protein (Head protein gp7) YP_002412097.1 1379347 D 585056 CDS YP_002412098.1 218704579 7154901 1380379..1380801 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1380801 7154901 ECUMN_1349 Escherichia coli UMN026 hypothetical protein YP_002412098.1 1380379 D 585056 CDS YP_002412099.1 218704580 7154902 1380794..1381147 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail attachment protein (Minor capsid protein FII) 1381147 7154902 ECUMN_1350 Escherichia coli UMN026 Tail attachment protein (Minor capsid protein FII) YP_002412099.1 1380794 D 585056 CDS YP_002412100.1 218704581 7154903 1381163..1381696 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 1381696 7154903 ECUMN_1351 Escherichia coli UMN026 Minor tail protein Z (GpZ) YP_002412100.1 1381163 D 585056 CDS YP_002412101.1 218704582 7154904 1381693..1382088 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 1382088 7154904 ECUMN_1352 Escherichia coli UMN026 Minor tail protein U YP_002412101.1 1381693 D 585056 CDS YP_002412102.1 218704583 7154905 1382096..1382845 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 1382845 7154905 ECUMN_1353 Escherichia coli UMN026 Major tail protein V YP_002412102.1 1382096 D 585056 CDS YP_002412103.1 218704584 7154906 1382864..1383295 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 1383295 7154906 ECUMN_1354 Escherichia coli UMN026 Minor tail protein G YP_002412103.1 1382864 D 585056 CDS YP_002412104.1 218704585 7154907 1383322..1383735 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 1383735 7154907 ECUMN_1355 Escherichia coli UMN026 Minor tail protein T YP_002412104.1 1383322 D 585056 CDS YP_002412105.1 218704586 7154908 1383716..1386277 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 1386277 7154908 ECUMN_1356 Escherichia coli UMN026 Minor tail protein H YP_002412105.1 1383716 D 585056 CDS YP_002412106.1 218704587 7154909 1386274..1386603 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 1386603 7154909 ECUMN_1357 Escherichia coli UMN026 Minor tail protein M YP_002412106.1 1386274 D 585056 CDS YP_002412107.1 218704588 7154910 complement(1386501..1386617) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1386617 7154910 ECUMN_1358 Escherichia coli UMN026 hypothetical protein YP_002412107.1 1386501 R 585056 CDS YP_002412108.1 218704589 7154911 1386603..1387301 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 1387301 7154911 ECUMN_1359 Escherichia coli UMN026 Minor tail protein L YP_002412108.1 1386603 D 585056 CDS YP_002412109.1 218704590 7154912 1387312..1388055 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail fiber component K 1388055 7154912 ECUMN_1360 Escherichia coli UMN026 tail fiber component K YP_002412109.1 1387312 D 585056 CDS YP_002412110.1 218704591 7154913 1387953..1388633 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 1388633 7154913 ECUMN_1361 Escherichia coli UMN026 Tail assembly protein I YP_002412110.1 1387953 D 585056 CDS YP_002412111.1 218704592 7154914 1388977..1392669 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J 1392669 7154914 ECUMN_1362 Escherichia coli UMN026 Host specificity protein J YP_002412111.1 1388977 D 585056 CDS YP_002412112.1 218704593 7154915 1392737..1393336 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Lom-like outer membrane protein of phage origin 1393336 7154915 ECUMN_1363 Escherichia coli UMN026 putative Lom-like outer membrane protein of phage origin YP_002412112.1 1392737 D 585056 CDS YP_002412113.1 218704594 7154916 1393488..1396514 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Side tail fiber protein from bacteriophage origin 1396514 7154916 ECUMN_1364 Escherichia coli UMN026 Side tail fiber protein from bacteriophage origin YP_002412113.1 1393488 D 585056 CDS YP_002412114.1 218704595 7154917 1396514..1397098 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative tail fiber chaperone; Qin prophage 1397098 tfaQ 7154917 tfaQ Escherichia coli UMN026 putative tail fiber chaperone; Qin prophage YP_002412114.1 1396514 D 585056 CDS YP_002412115.1 218704596 7158049 complement(1397153..1397737) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative AdoMet-dependent methyltransferase; DLP12 prophage 1397737 ybcY 7158049 ybcY Escherichia coli UMN026 putative AdoMet-dependent methyltransferase; DLP12 prophage YP_002412115.1 1397153 R 585056 CDS YP_002412116.1 218704597 7158389 1397878..1398144 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber assembly protein 1398144 7158389 ECUMN_1367 Escherichia coli UMN026 putative tail fiber assembly protein YP_002412116.1 1397878 D 585056 CDS YP_002412117.1 218704598 7154918 complement(1398376..1399239) 1 NC_011751.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1399239 potB 7154918 potB Escherichia coli UMN026 spermidine/putrescine ABC transporter membrane protein YP_002412117.1 1398376 R 585056 CDS YP_002412118.1 218704599 7157488 complement(1399223..1400359) 1 NC_011751.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein 1400359 potA 7157488 potA Escherichia coli UMN026 putrescine/spermidine ABC transporter ATPase protein YP_002412118.1 1399223 R 585056 CDS YP_002412119.1 218704600 7157487 complement(1400338..1400589) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1400589 7157487 ECUMN_1370 Escherichia coli UMN026 hypothetical protein YP_002412119.1 1400338 R 585056 CDS YP_002412120.1 218704601 7154919 1400609..1401835 1 NC_011751.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1401835 pepT 7154919 pepT Escherichia coli UMN026 peptidase T YP_002412120.1 1400609 D 585056 CDS YP_002412121.1 218704602 7157417 complement(1401884..1403005) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1403005 ycfD 7157417 ycfD Escherichia coli UMN026 hypothetical protein YP_002412121.1 1401884 R 585056 CDS YP_002412122.1 218704603 7158533 complement(1403081..1404541) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator; sensor protein PhoQ 1404541 phoQ 7158533 phoQ Escherichia coli UMN026 sensor protein PhoQ YP_002412122.1 1403081 R 585056 CDS YP_002412123.1 218704604 7157460 complement(1404541..1405212) 1 NC_011751.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1405212 phoP 7157460 phoP Escherichia coli UMN026 DNA-binding transcriptional regulator PhoP YP_002412123.1 1404541 R 585056 CDS YP_002412124.1 218704605 7157459 complement(1405381..1406751) 1 NC_011751.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1406751 purB 7157459 purB Escherichia coli UMN026 adenylosuccinate lyase YP_002412124.1 1405381 R 585056 CDS YP_002412125.1 218704606 7157573 complement(1406755..1407396) 1 NC_011751.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1407396 hflD 7157573 hflD Escherichia coli UMN026 hypothetical protein YP_002412125.1 1406755 R 585056 CDS YP_002412126.1 218704607 7156664 complement(1407432..1408538) 1 NC_011751.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA -specific 2-thiouridylase MnmA 1408538 mnmA 7156664 mnmA Escherichia coli UMN026 tRNA -specific 2-thiouridylase MnmA YP_002412126.1 1407432 R 585056 CDS YP_002412127.1 218704608 7158116 complement(1408592..1409053) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase 1409053 ymfB 7158116 ymfB Escherichia coli UMN026 bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase YP_002412127.1 1408592 R 585056 CDS YP_002412128.1 218704609 7159479 complement(1409063..1409716) 1 NC_011751.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1409716 ymfC 7159479 ymfC Escherichia coli UMN026 23S rRNA pseudouridine synthase E YP_002412128.1 1409063 R 585056 CDS YP_002412129.1 218704610 7159480 1409888..1411138 1 NC_011751.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1411138 icd 7159480 icd Escherichia coli UMN026 isocitrate dehydrogenase YP_002412129.1 1409888 D 585056 CDS YP_002412130.1 218704611 7156784 complement(1411252..1412394) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase 1412394 int 7156784 int Escherichia coli UMN026 phage integrase YP_002412130.1 1411252 R 585056 CDS YP_002412131.1 218704612 7156841 complement(1412384..1412620) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative excisionase 1412620 ymfG 7156841 ymfG Escherichia coli UMN026 putative excisionase YP_002412131.1 1412384 R 585056 CDS YP_002412132.1 218704613 7159481 complement(1412760..1412999) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1412999 7159481 ECUMN_1383 Escherichia coli UMN026 hypothetical protein YP_002412132.1 1412760 R 585056 CDS YP_002412133.1 218704614 7154920 complement(1413047..1413265) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1413265 7154920 ECUMN_1384 Escherichia coli UMN026 hypothetical protein YP_002412133.1 1413047 R 585056 CDS YP_002412134.1 218704615 7154921 complement(1413364..1413663) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1413663 7154921 ECUMN_1385 Escherichia coli UMN026 hypothetical protein YP_002412134.1 1413364 R 585056 CDS YP_002412135.1 218704616 7154922 complement(1413656..1413847) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1413847 7154922 ECUMN_1386 Escherichia coli UMN026 hypothetical protein YP_002412135.1 1413656 R 585056 CDS YP_002412136.1 218704617 7154923 complement(1413999..1414679) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin 1414679 7154923 ECUMN_1387 Escherichia coli UMN026 exonuclease from phage origin YP_002412136.1 1413999 R 585056 CDS YP_002412137.1 218704618 7154924 complement(1414676..1415461) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; recombination protein bet from phage origin 1415461 7154924 ECUMN_1388 Escherichia coli UMN026 recombination protein bet from phage origin YP_002412137.1 1414676 R 585056 CDS YP_002412138.1 218704619 7154925 complement(1415467..1415883) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Host-nuclease inhibitor protein gam from bacteriophage origin 1415883 gam 7154925 gam Escherichia coli UMN026 Host-nuclease inhibitor protein gam from bacteriophage origin YP_002412138.1 1415467 R 585056 CDS YP_002412139.1 218704620 7156502 complement(1415838..1416107) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host killing protein from bacteriophage origin 1416107 kil 7156502 kil Escherichia coli UMN026 Host killing protein from bacteriophage origin YP_002412139.1 1415838 R 585056 CDS YP_002412140.1 218704621 7156908 complement(1416187..1416555) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative single-stranded DNA binding protein of prophage 1416555 7156908 ECUMN_1391 Escherichia coli UMN026 putative single-stranded DNA binding protein of prophage YP_002412140.1 1416187 R 585056 CDS YP_002412141.1 218704622 7154926 1416816..1417397 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8335629; Product type h : extrachromosomal origin; Superinfection exclusion protein B 1417397 7154926 ECUMN_1392 Escherichia coli UMN026 Superinfection exclusion protein B YP_002412141.1 1416816 D 585056 CDS YP_002412142.1 218704623 7154927 complement(1417414..1417806) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulatory protein N 1417806 7154927 ECUMN_1393 Escherichia coli UMN026 putative regulatory protein N YP_002412142.1 1417414 R 585056 CDS YP_002412143.1 218704624 7154928 complement(1417808..1417981) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 1417981 7154928 ECUMN_1394 Escherichia coli UMN026 hypothetical protein YP_002412143.1 1417808 R 585056 CDS YP_002412144.1 218704625 7154929 complement(1418165..1419064) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1419064 7154929 ECUMN_1395 Escherichia coli UMN026 hypothetical protein YP_002412144.1 1418165 R 585056 CDS YP_002412145.1 218704626 7154930 complement(1419194..1419901) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; repressor protein of bacteriophage origin 1419901 cI 7154930 cI Escherichia coli UMN026 repressor protein of bacteriophage origin YP_002412145.1 1419194 R 585056 CDS YP_002412146.1 218704627 7155963 1419980..1420207 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin 1420207 cro 7155963 cro Escherichia coli UMN026 regulatory protein from bacteriophage origin YP_002412146.1 1419980 D 585056 CDS YP_002412147.1 218704628 7156016 1420314..1420613 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin; regulatory protein CII from phage origin 1420613 7156016 ECUMN_1398 Escherichia coli UMN026 regulatory protein CII from phage origin YP_002412147.1 1420314 D 585056 CDS YP_002412148.1 218704629 7157355 1420646..1421545 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; replication protein from bacteriophage origin 1421545 O 7157355 O Escherichia coli UMN026 replication protein from bacteriophage origin YP_002412148.1 1420646 D 585056 CDS YP_002412149.1 218704630 7157341 1421542..1422243 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative replication protein P of bacteriophage 1422243 7157341 ECUMN_1400 Escherichia coli UMN026 putative replication protein P of bacteriophage YP_002412149.1 1421542 D 585056 CDS YP_002412150.1 218704631 7154932 1422240..1422530 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; ren protein from phage origin 1422530 7154932 ECUMN_1401 Escherichia coli UMN026 ren protein from phage origin YP_002412150.1 1422240 D 585056 CDS YP_002412151.1 218704632 7154933 1422586..1423044 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; recombination protein ninB from phage origin 1423044 7154933 ECUMN_1402 Escherichia coli UMN026 recombination protein ninB from phage origin YP_002412151.1 1422586 D 585056 CDS YP_002412152.1 218704633 7154934 1422981..1423568 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative DNA N-6-adenine-methyltransferase from phage origin 1423568 7154934 ECUMN_1403 Escherichia coli UMN026 putative DNA N-6-adenine-methyltransferase from phage origin YP_002412152.1 1422981 D 585056 CDS YP_002412153.1 218704634 7154935 1423702..1424085 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1424085 7154935 ECUMN_1404 Escherichia coli UMN026 hypothetical protein YP_002412153.1 1423702 D 585056 CDS YP_002412154.1 218704635 7154936 1424292..1424654 1 NC_011751.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1424654 rusA 7154936 rusA Escherichia coli UMN026 endodeoxyribonuclease RUS YP_002412154.1 1424292 D 585056 CDS YP_002412155.1 218704636 7157821 1424862..1425254 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : putative factor; putative antitermination protein Q-like protein; DLP12 prophage 1425254 ybcQ 7157821 ybcQ Escherichia coli UMN026 putative antitermination protein Q-like protein; DLP12 prophage YP_002412155.1 1424862 D 585056 CDS YP_002412156.1 218704637 7158384 complement(1425411..1425935) 1 NC_011751.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 1425935 blc 7158384 blc Escherichia coli UMN026 outer membrane lipoprotein Blc YP_002412156.1 1425411 R 585056 CDS YP_002412157.1 218704638 7155886 1426128..1427087 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1427087 7155886 ECUMN_1408 Escherichia coli UMN026 hypothetical protein YP_002412157.1 1426128 D 585056 CDS YP_002412158.1 218704639 7154937 1427397..1428137 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative araC-type regulatory protein from bacteriophage origin 1428137 7154937 ECUMN_1409 Escherichia coli UMN026 putative araC-type regulatory protein from bacteriophage origin YP_002412158.1 1427397 D 585056 CDS YP_002412159.1 218704640 7154938 1428305..1428520 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative phage lysis protein S; DLP12 prophage 1428520 essD 7154938 essD Escherichia coli UMN026 putative phage lysis protein S; DLP12 prophage YP_002412159.1 1428305 D 585056 CDS YP_002412160.1 218704641 7156271 1428520..1429017 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : putative enzyme; putative lysozyme; DLP12 prophage 1429017 ybcS 7156271 ybcS Escherichia coli UMN026 putative lysozyme; DLP12 prophage YP_002412160.1 1428520 D 585056 CDS YP_002412161.1 218704642 7158386 1429014..1429475 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme; putative murein endopeptidase; DLP12 prophage 1429475 rzpD 7158386 rzpD Escherichia coli UMN026 putative murein endopeptidase; DLP12 prophage YP_002412161.1 1429014 D 585056 CDS YP_002412162.1 218704643 7157862 complement(1429507..1429800) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 95173101; Product type pm : putative membrane component; putative lipoprotein; DLP12 prophage 1429800 borD 7157862 borD Escherichia coli UMN026 putative lipoprotein; DLP12 prophage YP_002412162.1 1429507 R 585056 CDS YP_002412163.1 218704644 7155890 complement(1430160..1430354) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1430354 ynfO 7155890 ynfO Escherichia coli UMN026 hypothetical protein YP_002412163.1 1430160 R 585056 CDS YP_002412164.1 218704645 7159529 1430743..1431288 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92334985; Product type h : extrachromosomal origin; DNA packaging protein; DLP12 prophage 1431288 nohB 7159529 nohB Escherichia coli UMN026 DNA packaging protein; DLP12 prophage YP_002412164.1 1430743 D 585056 CDS YP_002412165.1 218704646 7157293 1431263..1433188 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Terminase large subunit from bacteriophage origin 1433188 A 7157293 A Escherichia coli UMN026 Terminase large subunit from bacteriophage origin YP_002412165.1 1431263 D 585056 CDS YP_002412166.1 218704647 7155654 1433185..1433391 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11302702; Product type h : extrachromosomal origin; Head-to-tail joining protein W (gpW) from bacteriophage origin 1433391 W 7155654 W Escherichia coli UMN026 Head-to-tail joining protein W (gpW) from bacteriophage origin YP_002412166.1 1433185 D 585056 CDS YP_002412167.1 218704648 7158214 1433388..1434989 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; portal protein; minor capsid protein 1434989 B 7158214 B Escherichia coli UMN026 portal protein; minor capsid protein YP_002412167.1 1433388 D 585056 CDS YP_002412168.1 218704649 7155847 1434970..1436289 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Minor capsid protein 1436289 C 7155847 C Escherichia coli UMN026 Minor capsid protein YP_002412168.1 1434970 D 585056 CDS YP_002412169.1 218704650 7155901 1436293..1436631 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Head decoration protein from bacteriophage origin 1436631 D 7155901 D Escherichia coli UMN026 Head decoration protein from bacteriophage origin YP_002412169.1 1436293 D 585056 CDS YP_002412170.1 218704651 7156098 1436660..1437712 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Major head coat protein from bacteriophage origin 1437712 E 7156098 E Escherichia coli UMN026 Major head coat protein from bacteriophage origin YP_002412170.1 1436660 D 585056 CDS YP_002412171.1 218704652 7156217 1437715..1438149 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; DNA packaging protein from bacteriophage origin 1438149 fI 7156217 fI Escherichia coli UMN026 DNA packaging protein from bacteriophage origin YP_002412171.1 1437715 D 585056 CDS YP_002412172.1 218704653 7156351 1438161..1438514 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; Tail attachment protein from bacteriophage origin 1438514 fII 7156351 fII Escherichia coli UMN026 Tail attachment protein from bacteriophage origin YP_002412172.1 1438161 D 585056 CDS YP_002412173.1 218704654 7156355 1438526..1439104 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GpZ) 1439104 7156355 ECUMN_1424 Escherichia coli UMN026 Minor tail protein Z (GpZ) YP_002412173.1 1438526 D 585056 CDS YP_002412174.1 218704655 7154939 1439101..1439496 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 1439496 7154939 ECUMN_1425 Escherichia coli UMN026 Minor tail protein U YP_002412174.1 1439101 D 585056 CDS YP_002412175.1 218704656 7154940 1439474..1440244 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 1440244 7154940 ECUMN_1426 Escherichia coli UMN026 Major tail protein V YP_002412175.1 1439474 D 585056 CDS YP_002412176.1 218704657 7154941 1440260..1440682 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein G 1440682 7154941 ECUMN_1427 Escherichia coli UMN026 Minor tail protein G YP_002412176.1 1440260 D 585056 CDS YP_002412177.1 218704658 7154942 1440664..1441098 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein T 1441098 7154942 ECUMN_1428 Escherichia coli UMN026 Minor tail protein T YP_002412177.1 1440664 D 585056 CDS YP_002412178.1 218704659 7154943 1441091..1443670 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein H 1443670 7154943 ECUMN_1429 Escherichia coli UMN026 Minor tail protein H YP_002412178.1 1441091 D 585056 CDS YP_002412179.1 218704660 7154944 1443667..1443996 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 1443996 7154944 ECUMN_1430 Escherichia coli UMN026 Minor tail protein M YP_002412179.1 1443667 D 585056 CDS YP_002412180.1 218704661 7154945 1443996..1444694 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 1444694 7154945 ECUMN_1431 Escherichia coli UMN026 Minor tail protein L YP_002412180.1 1443996 D 585056 CDS YP_002412181.1 218704662 7154946 1444700..1445443 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage 1445443 7154946 ECUMN_1432 Escherichia coli UMN026 putative tail fiber component K of prophage YP_002412181.1 1444700 D 585056 CDS YP_002412182.1 218704663 7154947 1445341..1446012 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 1446012 7154947 ECUMN_1433 Escherichia coli UMN026 Tail assembly protein I YP_002412182.1 1445341 D 585056 CDS YP_002412183.1 218704664 7154948 1446073..1449555 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 1449555 7154948 ECUMN_1434 Escherichia coli UMN026 Host specificity protein J of prophage YP_002412183.1 1446073 D 585056 CDS YP_002412184.1 218704665 7154950 1451632..1451910 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1451910 7154950 ECUMN_1436 Escherichia coli UMN026 hypothetical protein YP_002412184.1 1451632 D 585056 CDS YP_002412185.1 218704666 7154951 1451923..1452216 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1452216 7154951 ECUMN_1437 Escherichia coli UMN026 hypothetical protein YP_002412185.1 1451923 D 585056 CDS YP_002412186.1 218704667 7154952 complement(1452308..1453165) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, inner membrane component 1453165 sitD 7154952 sitD Escherichia coli UMN026 iron transport protein, inner membrane component YP_002412186.1 1452308 R 585056 CDS YP_002412187.1 218704668 7157932 complement(1453162..1454019) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, inner membrane component 1454019 sitC 7157932 sitC Escherichia coli UMN026 iron transport protein, inner membrane component YP_002412187.1 1453162 R 585056 CDS YP_002412188.1 218704669 7157931 complement(1454016..1454843) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component; iron transport protein, ATP-binding component 1454843 sitB 7157931 sitB Escherichia coli UMN026 iron transport protein, ATP-binding component YP_002412188.1 1454016 R 585056 CDS YP_002412189.1 218704670 7157930 complement(1454843..1455757) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type t : transporter; iron transport protein, periplasmic-binding protein 1455757 sitA 7157930 sitA Escherichia coli UMN026 iron transport protein, periplasmic-binding protein YP_002412189.1 1454843 R 585056 CDS YP_002412190.1 218704671 7157929 1456445..1457215 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1457215 7157929 ECUMN_1442 Escherichia coli UMN026 hypothetical protein YP_002412190.1 1456445 D 585056 CDS YP_002412191.1 218704672 7154953 1457338..1457493 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1457493 7154953 ECUMN_1443 Escherichia coli UMN026 hypothetical protein YP_002412191.1 1457338 D 585056 CDS YP_002412192.1 218704673 7156785 complement(1457942..1458265) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9603997; hypothetical protein 1458265 elbA 7156785 elbA Escherichia coli UMN026 hypothetical protein YP_002412192.1 1457942 R 585056 CDS YP_002412193.1 218704674 7156238 complement(1458968..1459372) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1459372 ycgX 7156238 ycgX Escherichia coli UMN026 hypothetical protein YP_002412193.1 1458968 R 585056 CDS YP_002412194.1 218704675 7158557 complement(1459593..1460324) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1460324 ycgE 7158557 ycgE Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412194.1 1459593 R 585056 CDS YP_002412195.1 218704676 7158547 complement(1460529..1461740) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16533062, 15453820; Product type pe : putative enzyme; putative cyclic-di-GMP phosphodiesterase 1461740 ycgF 7158547 ycgF Escherichia coli UMN026 putative cyclic-di-GMP phosphodiesterase YP_002412195.1 1460529 R 585056 CDS YP_002412196.1 218704677 7158548 1462054..1462290 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462290 ycgZ 7158548 ycgZ Escherichia coli UMN026 hypothetical protein YP_002412196.1 1462054 D 585056 CDS YP_002412197.1 218704678 7158558 1462333..1462605 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462605 ymgA 7158558 ymgA Escherichia coli UMN026 hypothetical protein YP_002412197.1 1462333 D 585056 CDS YP_002412198.1 218704679 7159486 1462634..1462900 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462900 ymgB 7159486 ymgB Escherichia coli UMN026 hypothetical protein YP_002412198.1 1462634 D 585056 CDS YP_002412199.1 218704680 7159487 1463013..1463261 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1463261 ymgC 7159487 ymgC Escherichia coli UMN026 hypothetical protein YP_002412199.1 1463013 D 585056 CDS YP_002412200.1 218704681 7159488 complement(1463564..1463737) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1463737 7159488 ECUMN_1453 Escherichia coli UMN026 hypothetical protein YP_002412200.1 1463564 R 585056 CDS YP_002412201.1 218704682 7158549 1465252..1465470 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1465470 ymgF 7158549 ymgF Escherichia coli UMN026 hypothetical protein YP_002412201.1 1465252 D 585056 CDS YP_002412202.1 218704683 7159491 complement(1465475..1465618) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1465618 7159491 ECUMN_1456 Escherichia coli UMN026 hypothetical protein YP_002412202.1 1465475 R 585056 CDS YP_002412203.1 218704684 7154956 1465870..1466853 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1466853 7154956 ECUMN_1458 Escherichia coli UMN026 hypothetical protein YP_002412203.1 1465870 D 585056 CDS YP_002412204.1 218704685 7154957 1466883..1468532 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1468532 7154957 ECUMN_1459 Escherichia coli UMN026 hypothetical protein YP_002412204.1 1466883 D 585056 CDS YP_002412205.1 218704686 7154958 complement(1468588..1468917) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1468917 ymgD 7154958 ymgD Escherichia coli UMN026 hypothetical protein YP_002412205.1 1468588 R 585056 CDS YP_002412206.1 218704687 7159489 complement(1468927..1469202) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1469202 ymgG 7159489 ymgG Escherichia coli UMN026 hypothetical protein YP_002412206.1 1468927 R 585056 CDS YP_002412207.1 218704688 7159492 1469748..1470191 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1470191 7159492 ECUMN_1462 Escherichia coli UMN026 hypothetical protein YP_002412207.1 1469748 D 585056 CDS YP_002412208.1 218704689 7154959 complement(1470556..1470822) 1 NC_011751.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1470822 minE 7154959 minE Escherichia coli UMN026 cell division topological specificity factor MinE YP_002412208.1 1470556 R 585056 CDS YP_002412209.1 218704690 7157135 complement(1470826..1471638) 1 NC_011751.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1471638 minD 7157135 minD Escherichia coli UMN026 cell division inhibitor MinD YP_002412209.1 1470826 R 585056 CDS YP_002412210.1 218704691 7157134 complement(1471662..1472357) 1 NC_011751.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1472357 minC 7157134 minC Escherichia coli UMN026 septum formation inhibitor YP_002412210.1 1471662 R 585056 CDS YP_002412211.1 218704692 7157133 1472877..1473245 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1473245 ycgJ 7157133 ycgJ Escherichia coli UMN026 hypothetical protein YP_002412211.1 1472877 D 585056 CDS YP_002412212.1 218704693 7158550 complement(1473348..1473749) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1473749 ycgK 7158550 ycgK Escherichia coli UMN026 hypothetical protein YP_002412212.1 1473348 R 585056 CDS YP_002412213.1 218704694 7158551 1473957..1474283 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1474283 ycgL 7158551 ycgL Escherichia coli UMN026 hypothetical protein YP_002412213.1 1473957 D 585056 CDS YP_002412214.1 218704695 7158552 1474355..1475014 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : putative enzyme; hypothetical protein 1475014 ycgM 7158552 ycgM Escherichia coli UMN026 hypothetical protein YP_002412214.1 1474355 D 585056 CDS YP_002412215.1 218704696 7158553 1475106..1475552 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1475552 ycgN 7158553 ycgN Escherichia coli UMN026 hypothetical protein YP_002412215.1 1475106 D 585056 CDS YP_002412216.1 218704697 7158554 complement(1475759..1476670) 1 NC_011751.1 Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E 1476670 hlyE 7158554 hlyE Escherichia coli UMN026 hemolysin E YP_002412216.1 1475759 R 585056 CDS YP_002412217.1 218704698 7156688 1477042..1477461 1 NC_011751.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1477461 umuD 7156688 umuD Escherichia coli UMN026 DNA polymerase V subunit UmuD YP_002412217.1 1477042 D 585056 CDS YP_002412218.1 218704699 7158187 1477461..1478729 1 NC_011751.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1478729 umuC 7158187 umuC Escherichia coli UMN026 DNA polymerase V subunit UmuC YP_002412218.1 1477461 D 585056 CDS YP_002412219.1 218704700 7158186 complement(1478775..1479305) 1 NC_011751.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1479305 dsbB 7158186 dsbB Escherichia coli UMN026 disulfide bond formation protein B YP_002412219.1 1478775 R 585056 CDS YP_002412220.1 218704701 7156203 complement(1479451..1480992) 1 NC_011751.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1480992 nhaB 7156203 nhaB Escherichia coli UMN026 sodium/proton antiporter YP_002412220.1 1479451 R 585056 CDS YP_002412221.1 218704702 7157272 1481214..1481933 1 NC_011751.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1481933 fadR 7157272 fadR Escherichia coli UMN026 fatty acid metabolism regulator YP_002412221.1 1481214 D 585056 CDS YP_002412222.1 218704703 7156308 complement(1481984..1483516) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; SpoVR family protein 1483516 ycgB 7156308 ycgB Escherichia coli UMN026 SpoVR family protein YP_002412222.1 1481984 R 585056 CDS YP_002412223.1 218704704 7158546 1483846..1485144 1 NC_011751.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1485144 dadA 7158546 dadA Escherichia coli UMN026 D-amino acid dehydrogenase small subunit YP_002412223.1 1483846 D 585056 CDS YP_002412224.1 218704705 7156103 1485154..1486224 1 NC_011751.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1486224 dadX 7156103 dadX Escherichia coli UMN026 alanine racemase YP_002412224.1 1485154 D 585056 CDS YP_002412225.1 218704706 7156104 complement(1486392..1487828) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1487828 7156104 ECUMN_1480 Escherichia coli UMN026 hypothetical protein YP_002412225.1 1486392 R 585056 CDS YP_002412226.1 218704707 7154960 1488154..1488375 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1488375 7154960 ECUMN_1481 Escherichia coli UMN026 hypothetical protein YP_002412226.1 1488154 D 585056 CDS YP_002412227.1 218704708 7154961 complement(1488477..1490213) 1 NC_011751.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1490213 cvrA 7154961 cvrA Escherichia coli UMN026 potassium/proton antiporter YP_002412227.1 1488477 R 585056 CDS YP_002412228.1 218704709 7156059 complement(1490308..1491222) 1 NC_011751.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1491222 ldcA 7156059 ldcA Escherichia coli UMN026 L,D-carboxypeptidase A YP_002412228.1 1490308 R 585056 CDS YP_002412229.1 218704710 7156935 1491322..1491933 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme; lytic murein endotransglycosylase E 1491933 emtA 7156935 emtA Escherichia coli UMN026 lytic murein endotransglycosylase E YP_002412229.1 1491322 D 585056 CDS YP_002412230.1 218704711 7156245 complement(1491935..1492669) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 11031114; Product type cp : cell process; protein involved in flagellar function 1492669 ycgR 7156245 ycgR Escherichia coli UMN026 protein involved in flagellar function YP_002412230.1 1491935 R 585056 CDS YP_002412231.1 218704712 7158555 1492870..1493124 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative inner membrane protein with transglycosylase-associated domain 1493124 ymgE 7158555 ymgE Escherichia coli UMN026 putative inner membrane protein with transglycosylase-associated domain YP_002412231.1 1492870 D 585056 CDS YP_002412232.1 218704713 7159490 complement(1493174..1495165) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative outer membrane receptor 1495165 prrA 7159490 prrA Escherichia coli UMN026 putative outer membrane receptor YP_002412232.1 1493174 R 585056 CDS YP_002412233.1 218704714 7157545 complement(1495170..1496024) 1 NC_011751.1 involved in molybdenum transport; molybdenum transport protein ModD 1496024 modD 7157545 modD Escherichia coli UMN026 molybdenum transport protein ModD YP_002412233.1 1495170 R 585056 CDS YP_002412234.1 218704715 7157155 complement(1496021..1496833) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative SAM-dependent methyltransferase 1496833 7157155 ECUMN_1489 Escherichia coli UMN026 putative SAM-dependent methyltransferase YP_002412234.1 1496021 R 585056 CDS YP_002412235.1 218704716 7154962 complement(1496843..1497739) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ABC transporter ATP-binding protein 1497739 7154962 ECUMN_1490 Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002412235.1 1496843 R 585056 CDS YP_002412236.1 218704717 7154963 complement(1497598..1498578) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative ABC transporter permease protein 1498578 7154963 ECUMN_1491 Escherichia coli UMN026 putative ABC transporter permease protein YP_002412236.1 1497598 R 585056 CDS YP_002412237.1 218704718 7154964 complement(1498578..1499642) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter periplasmic binding protein 1499642 7154964 ECUMN_1492 Escherichia coli UMN026 putative ABC transporter periplasmic binding protein YP_002412237.1 1498578 R 585056 CDS YP_002412238.1 218704719 7154965 complement(1499929..1501626) 1 NC_011751.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1501626 treA 7154965 treA Escherichia coli UMN026 trehalase YP_002412238.1 1499929 R 585056 CDS YP_002412239.1 218704720 7158102 complement(1501945..1503363) 1 NC_011751.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M 1503363 dhaH 7158102 dhaH Escherichia coli UMN026 dihydroxyacetone kinase subunit M YP_002412239.1 1501945 R 585056 CDS YP_002412240.1 218704721 7156156 complement(1503374..1504006) 1 NC_011751.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL 1504006 dhaL 7156156 dhaL Escherichia coli UMN026 dihydroxyacetone kinase subunit DhaL YP_002412240.1 1503374 R 585056 CDS YP_002412241.1 218704722 7156158 complement(1504017..1505087) 1 NC_011751.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 1505087 dhaK 7156158 dhaK Escherichia coli UMN026 dihydroxyacetone kinase subunit DhaK YP_002412241.1 1504017 R 585056 CDS YP_002412242.1 218704723 7156157 1505315..1507234 1 NC_011751.1 Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1507234 dhaR 7156157 dhaR Escherichia coli UMN026 DNA-binding transcriptional regulator DhaR YP_002412242.1 1505315 D 585056 CDS YP_002412243.1 218704724 7156159 complement(1507334..1510201) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pf : putative factor; putative adhesin 1510201 ycgV 7156159 ycgV Escherichia coli UMN026 putative adhesin YP_002412243.1 1507334 R 585056 CDS YP_002412244.1 218704725 7158556 complement(1511046..1512137) 1 NC_011751.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1512137 ychF 7158556 ychF Escherichia coli UMN026 GTP-dependent nucleic acid-binding protein EngD YP_002412244.1 1511046 R 585056 CDS YP_002412245.1 218704726 7158561 complement(1512254..1512838) 1 NC_011751.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1512838 pth 7158561 pth Escherichia coli UMN026 peptidyl-tRNA hydrolase YP_002412245.1 1512254 R 585056 CDS YP_002412246.1 218704727 7157562 1513116..1513394 1 NC_011751.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1513394 ychH 7157562 ychH Escherichia coli UMN026 hypothetical protein YP_002412246.1 1513116 D 585056 CDS YP_002412247.1 218704728 7158562 complement(1513449..1515128) 1 NC_011751.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM 1515128 ychM 7158562 ychM Escherichia coli UMN026 putative sulfate transporter YchM YP_002412247.1 1513449 R 585056 CDS YP_002412248.1 218704729 7158564 complement(1515253..1516200) 1 NC_011751.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1516200 prsA 7158564 prsA Escherichia coli UMN026 ribose-phosphate pyrophosphokinase YP_002412248.1 1515253 R 585056 CDS YP_002412249.1 218704730 7157546 complement(1516351..1517202) 1 NC_011751.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1517202 ipk 7157546 ipk Escherichia coli UMN026 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002412249.1 1516351 R 585056 CDS YP_002412250.1 218704731 7156865 complement(1517202..1517825) 1 NC_011751.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1517825 lolB 7156865 lolB Escherichia coli UMN026 outer membrane lipoprotein LolB YP_002412250.1 1517202 R 585056 CDS YP_002412251.1 218704732 7156995 1518039..1519295 1 NC_011751.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1519295 hemA 7156995 hemA Escherichia coli UMN026 glutamyl-tRNA reductase YP_002412251.1 1518039 D 585056 CDS YP_002412252.1 218704733 7156650 1519336..1520418 1 NC_011751.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1520418 prfA 7156650 prfA Escherichia coli UMN026 peptide chain release factor 1 YP_002412252.1 1519336 D 585056 CDS YP_002412253.1 218704734 7157517 1520418..1521251 1 NC_011751.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1521251 prmC 7157517 prmC Escherichia coli UMN026 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002412253.1 1520418 D 585056 CDS YP_002412254.1 218704735 7157529 1521248..1521640 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator; putative transcriptional regulator 1521640 ychQ 7157529 ychQ Escherichia coli UMN026 putative transcriptional regulator YP_002412254.1 1521248 D 585056 CDS YP_002412255.1 218704736 7158567 1521644..1522453 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator; putative transcriptional regulator 1522453 ychA 7158567 ychA Escherichia coli UMN026 putative transcriptional regulator YP_002412255.1 1521644 D 585056 CDS YP_002412256.1 218704737 7158559 1522489..1523343 1 NC_011751.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1523343 kdsA 7158559 kdsA Escherichia coli UMN026 2-dehydro-3-deoxyphosphooctonate aldolase YP_002412256.1 1522489 D 585056 CDS YP_002412257.1 218704738 7156895 complement(1523491..1523598) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; toxic polypeptide, small 1523598 ldrB 7156895 ldrB Escherichia coli UMN026 toxic polypeptide, small YP_002412257.1 1523491 R 585056 CDS YP_002412258.1 218704739 7157635 complement(1524026..1524193) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type f : factor; small toxic polypeptide 1524193 ldrB 7157635 ldrB Escherichia coli UMN026 small toxic polypeptide YP_002412258.1 1524026 R 585056 CDS YP_002412259.1 218704740 7157634 complement(1524539..1525639) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter; calcium/sodium:proton antiporter 1525639 chaA 7157634 chaA Escherichia coli UMN026 calcium/sodium:proton antiporter YP_002412259.1 1524539 R 585056 CDS YP_002412260.1 218704741 7155942 1525909..1526139 1 NC_011751.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1526139 chaB 7155942 chaB Escherichia coli UMN026 cation transport regulator YP_002412260.1 1525909 D 585056 CDS YP_002412261.1 218704742 7155943 1526276..1526992 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; regulatory protein for cation transport 1526992 chaC 7155943 chaC Escherichia coli UMN026 regulatory protein for cation transport YP_002412261.1 1526276 D 585056 CDS YP_002412262.1 218704743 7155944 complement(1527036..1527389) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1527389 ychN 7155944 ychN Escherichia coli UMN026 hypothetical protein YP_002412262.1 1527036 R 585056 CDS YP_002412263.1 218704744 7158565 1527716..1528969 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : putative factor; hypothetical protein 1528969 ychP 7158565 ychP Escherichia coli UMN026 hypothetical protein YP_002412263.1 1527716 D 585056 CDS YP_002412264.1 218704745 7158566 complement(1528970..1529620) 1 NC_011751.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1529620 narL 7158566 narL Escherichia coli UMN026 transcriptional regulator NarL YP_002412264.1 1528970 R 585056 CDS YP_002412265.1 218704746 7157252 complement(1529613..1531409) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator; nitrate/nitrite sensor protein NarX 1531409 narX 7157252 narX Escherichia coli UMN026 nitrate/nitrite sensor protein NarX YP_002412265.1 1529613 R 585056 CDS YP_002412266.1 218704747 7157258 1531748..1533139 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter; nitrate/nitrite transporter 1533139 narK 7157258 narK Escherichia coli UMN026 nitrate/nitrite transporter YP_002412266.1 1531748 D 585056 CDS YP_002412267.1 218704748 7157251 1533534..1537277 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme; nitrate reductase 1 subunit alpha 1537277 narG 7157251 narG Escherichia coli UMN026 nitrate reductase 1 subunit alpha YP_002412267.1 1533534 D 585056 CDS YP_002412268.1 218704749 7157247 1537274..1538812 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier; nitrate reductase 1, beta (Fe-S) subunit 1538812 narH 7157247 narH Escherichia coli UMN026 nitrate reductase 1, beta (Fe-S) subunit YP_002412268.1 1537274 D 585056 CDS YP_002412269.1 218704750 7157248 1538809..1539519 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor; molybdenum-cofactor-assembly chaperone subunit delta 1539519 narJ 7157248 narJ Escherichia coli UMN026 molybdenum-cofactor-assembly chaperone subunit delta YP_002412269.1 1538809 D 585056 CDS YP_002412270.1 218704751 7157250 1539519..1540196 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier; nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1540196 narI 7157250 narI Escherichia coli UMN026 nitrate reductase 1, gamma (cytochrome b(NR)) subunit YP_002412270.1 1539519 D 585056 CDS YP_002412271.1 218704752 7158568 1540555..1541004 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1541004 7158568 ECUMN_1528 Escherichia coli UMN026 hypothetical protein YP_002412271.1 1540555 D 585056 CDS YP_002412272.1 218704753 7155639 complement(1541100..1541942) 1 NC_011751.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1541942 purU 7155639 purU Escherichia coli UMN026 formyltetrahydrofolate deformylase YP_002412272.1 1541100 R 585056 CDS YP_002412273.1 218704754 7157585 complement(1541992..1542450) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1542450 ychJ 7157585 ychJ Escherichia coli UMN026 hypothetical protein YP_002412273.1 1541992 R 585056 CDS YP_002412274.1 218704755 7158563 1542563..1543468 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 1543468 rssA 7158563 rssA Escherichia coli UMN026 hypothetical protein YP_002412274.1 1542563 D 585056 CDS YP_002412275.1 218704756 7157801 1543560..1544573 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator; response regulator of RpoS 1544573 rssB 7157801 rssB Escherichia coli UMN026 response regulator of RpoS YP_002412275.1 1543560 D 585056 CDS YP_002412276.1 218704757 7157802 1544775..1545683 1 NC_011751.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1545683 galU 7157802 galU Escherichia coli UMN026 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_002412276.1 1544775 D 585056 CDS YP_002412277.1 218704758 7156501 1545737..1545925 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1545925 7156501 ECUMN_1534 Escherichia coli UMN026 hypothetical protein YP_002412277.1 1545737 D 585056 CDS YP_002412278.1 218704759 7154967 1545831..1546340 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 1546340 7154967 ECUMN_1535 Escherichia coli UMN026 transposase IS605 family, IS200 group YP_002412278.1 1545831 D 585056 CDS YP_002412279.1 218704760 7154968 complement(1546540..1546953) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator; global DNA-binding transcriptional dual regulator H-NS 1546953 hns 7154968 hns Escherichia coli UMN026 global DNA-binding transcriptional dual regulator H-NS YP_002412279.1 1546540 R 585056 CDS YP_002412280.1 218704761 7156690 1547557..1548174 1 NC_011751.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1548174 tdk 7156690 tdk Escherichia coli UMN026 thymidine kinase YP_002412280.1 1547557 D 585056 CDS YP_002412281.1 218704762 7158044 complement(1548477..1551152) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1551152 adhE 7158044 adhE Escherichia coli UMN026 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002412281.1 1548477 R 585056 CDS YP_002412282.1 218704763 7155698 1551629..1552276 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1552276 ychE 7155698 ychE Escherichia coli UMN026 hypothetical protein YP_002412282.1 1551629 D 585056 CDS YP_002412283.1 218704764 7158560 1553014..1554645 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter; oligopeptide ABC transporter periplasmic-binding protein 1554645 oppA 7158560 oppA Escherichia coli UMN026 oligopeptide ABC transporter periplasmic-binding protein YP_002412283.1 1553014 D 585056 CDS YP_002412284.1 218704765 7157357 1554731..1555651 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter; oligopeptide transporter permease 1555651 oppB 7157357 oppB Escherichia coli UMN026 oligopeptide transporter permease YP_002412284.1 1554731 D 585056 CDS YP_002412285.1 218704766 7157358 1555666..1556574 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter membrane protein 1556574 oppC 7157358 oppC Escherichia coli UMN026 oligopeptide ABC transporter membrane protein YP_002412285.1 1555666 D 585056 CDS YP_002412286.1 218704767 7157359 1556586..1557599 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide transporter ATP-binding component 1557599 oppD 7157359 oppD Escherichia coli UMN026 oligopeptide transporter ATP-binding component YP_002412286.1 1556586 D 585056 CDS YP_002412287.1 218704768 7157360 1557596..1558600 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter ATP-binding protein 1558600 oppF 7157360 oppF Escherichia coli UMN026 oligopeptide ABC transporter ATP-binding protein YP_002412287.1 1557596 D 585056 CDS YP_002412288.1 218704769 7157361 complement(1558653..1558982) 1 NC_011751.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1558982 yciU 7157361 yciU Escherichia coli UMN026 dsDNA-mimic protein YP_002412288.1 1558653 R 585056 CDS YP_002412289.1 218704770 7158583 complement(1559017..1560477) 1 NC_011751.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1560477 cls 7158583 cls Escherichia coli UMN026 cardiolipin synthetase YP_002412289.1 1559017 R 585056 CDS YP_002412290.1 218704771 7155983 1560509..1560793 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1560793 7155983 ECUMN_1547 Escherichia coli UMN026 hypothetical protein YP_002412290.1 1560509 D 585056 CDS YP_002412291.1 218704772 7154969 1560739..1560906 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1560906 7154969 ECUMN_1548 Escherichia coli UMN026 hypothetical protein YP_002412291.1 1560739 D 585056 CDS YP_002412292.1 218704773 7154970 complement(1560848..1562101) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12220501, 12912904, 94224769, 98319474; Product type t : transporter; voltage-gated potassium channel 1562101 kch 7154970 kch Escherichia coli UMN026 voltage-gated potassium channel YP_002412292.1 1560848 R 585056 CDS YP_002412293.1 218704774 7156886 complement(1562402..1562698) 1 NC_011751.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1562698 yciI 7156886 yciI Escherichia coli UMN026 YciI-like protein YP_002412293.1 1562402 R 585056 CDS YP_002412294.1 218704775 7158576 1562922..1563641 1 NC_011751.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1563641 tonB 7158576 tonB Escherichia coli UMN026 transport protein TonB YP_002412294.1 1562922 D 585056 CDS YP_002412295.1 218704776 7158086 complement(1563681..1564079) 1 NC_011751.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1564079 yciA 7158086 yciA Escherichia coli UMN026 acyl-CoA thioester hydrolase YP_002412295.1 1563681 R 585056 CDS YP_002412296.1 218704777 7158569 complement(1564184..1564723) 1 NC_011751.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1564723 yciB 7158569 yciB Escherichia coli UMN026 intracellular septation protein A YP_002412296.1 1564184 R 585056 CDS YP_002412297.1 218704778 7158570 complement(1564753..1565496) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1565496 yciC 7158570 yciC Escherichia coli UMN026 hypothetical protein YP_002412297.1 1564753 R 585056 CDS YP_002412298.1 218704779 7158571 1565853..1566491 1 NC_011751.1 receptor for colicin S4; outer membrane protein W 1566491 ompW 7158571 ompW Escherichia coli UMN026 outer membrane protein W YP_002412298.1 1565853 D 585056 CDS YP_002412299.1 218704780 7157351 complement(1566551..1567057) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15388941, 3058546, 8455549; hypothetical protein 1567057 yciE 7157351 yciE Escherichia coli UMN026 hypothetical protein YP_002412299.1 1566551 R 585056 CDS YP_002412300.1 218704781 7158572 complement(1567103..1567603) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3058546, 8455549; hypothetical protein 1567603 yciF 7158572 yciF Escherichia coli UMN026 hypothetical protein YP_002412300.1 1567103 R 585056 CDS YP_002412301.1 218704782 7158573 complement(1567689..1567868) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1567868 yciG 7158573 yciG Escherichia coli UMN026 hypothetical protein YP_002412301.1 1567689 R 585056 CDS YP_002412302.1 218704783 7158574 complement(1568249..1569055) 1 NC_011751.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1569055 trpA 7158574 trpA Escherichia coli UMN026 tryptophan synthase subunit alpha YP_002412302.1 1568249 R 585056 CDS YP_002412303.1 218704784 7158117 complement(1569055..1570248) 1 NC_011751.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1570248 trpB 7158117 trpB Escherichia coli UMN026 tryptophan synthase subunit beta YP_002412303.1 1569055 R 585056 CDS YP_002412304.1 218704785 7158118 complement(1570260..1571618) 1 NC_011751.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1571618 trpC 7158118 trpC Escherichia coli UMN026 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002412304.1 1570260 R 585056 CDS YP_002412305.1 218704786 7158119 complement(1571622..1573217) 1 NC_011751.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1573217 trpD 7158119 trpD Escherichia coli UMN026 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_002412305.1 1571622 R 585056 CDS YP_002412306.1 218704787 7158120 complement(1573217..1574779) 1 NC_011751.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1574779 trpE 7158120 trpE Escherichia coli UMN026 anthranilate synthase component I YP_002412306.1 1573217 R 585056 CDS YP_002412308.1 218704789 7158122 1575053..1575934 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1575934 yciV 7158122 yciV Escherichia coli UMN026 hypothetical protein YP_002412308.1 1575053 D 585056 CDS YP_002412309.1 218704790 7158584 1575931..1576551 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1576551 yciO 7158584 yciO Escherichia coli UMN026 hypothetical protein YP_002412309.1 1575931 D 585056 CDS YP_002412310.1 218704791 7158580 1576579..1578474 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1578474 yciQ 7158580 yciQ Escherichia coli UMN026 hypothetical protein YP_002412310.1 1576579 D 585056 CDS YP_002412311.1 218704792 7158581 1578685..1579560 1 NC_011751.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1579560 rluB 7158581 rluB Escherichia coli UMN026 23S rRNA pseudouridylate synthase B YP_002412311.1 1578685 D 585056 CDS YP_002412312.1 218704793 7157700 complement(1579600..1580190) 1 NC_011751.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1580190 btuR 7157700 btuR Escherichia coli UMN026 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002412312.1 1579600 R 585056 CDS YP_002412313.1 218704794 7155899 complement(1580187..1580945) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; short chain dehydrogenase 1580945 yciK 7155899 yciK Escherichia coli UMN026 short chain dehydrogenase YP_002412313.1 1580187 R 585056 CDS YP_002412314.1 218704795 7158577 1581165..1582214 1 NC_011751.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1582214 sohB 7158577 sohB Escherichia coli UMN026 putative periplasmic protease YP_002412314.1 1581165 D 585056 CDS YP_002412315.1 218704796 7157949 complement(1582250..1582501) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784; hypothetical protein 1582501 yciN 7157949 yciN Escherichia coli UMN026 hypothetical protein YP_002412315.1 1582250 R 585056 CDS YP_002412316.1 218704797 7158579 1582546..1582758 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1582758 7158579 ECUMN_1572 Escherichia coli UMN026 hypothetical protein YP_002412316.1 1582546 D 585056 CDS YP_002412317.1 218704798 7154971 1582881..1585478 1 NC_011751.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1585478 topA 7154971 topA Escherichia coli UMN026 DNA topoisomerase I YP_002412317.1 1582881 D 585056 CDS YP_002412318.1 218704799 7158087 1585688..1586662 1 NC_011751.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1586662 cysB 7158087 cysB Escherichia coli UMN026 transcriptional regulator CysB YP_002412318.1 1585688 D 585056 CDS YP_002412319.1 218704800 7156079 1586957..1587121 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1587121 7156079 ECUMN_1575 Escherichia coli UMN026 hypothetical protein YP_002412319.1 1586957 D 585056 CDS YP_002412320.1 218704801 7154972 1587103..1587291 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1587291 7154972 ECUMN_1576 Escherichia coli UMN026 hypothetical protein YP_002412320.1 1587103 D 585056 CDS YP_002412321.1 218704802 7154973 1587428..1587610 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1587610 7154973 ECUMN_1577 Escherichia coli UMN026 hypothetical protein YP_002412321.1 1587428 D 585056 CDS YP_002412322.1 218704803 7154974 1587664..1590339 1 NC_011751.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1590339 acnA 7154974 acnA Escherichia coli UMN026 aconitate hydratase YP_002412322.1 1587664 D 585056 CDS YP_002412323.1 218704804 7155681 complement(1590403..1590993) 1 NC_011751.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1590993 ribA 7155681 ribA Escherichia coli UMN026 GTP cyclohydrolase II YP_002412323.1 1590403 R 585056 CDS YP_002412324.1 218704805 7157682 1591163..1591927 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme; phosphatidylglycerophosphatase B 1591927 pgpB 7157682 pgpB Escherichia coli UMN026 phosphatidylglycerophosphatase B YP_002412324.1 1591163 D 585056 CDS YP_002412325.1 218704806 7157431 1592076..1592384 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1592384 yciS 7157431 yciS Escherichia coli UMN026 hypothetical protein YP_002412325.1 1592076 D 585056 CDS YP_002412326.1 218704807 7158582 1592391..1593560 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; tetratricopeptide repeat-containing protein 1593560 yciM 7158582 yciM Escherichia coli UMN026 tetratricopeptide repeat-containing protein YP_002412326.1 1592391 D 585056 CDS YP_002412327.1 218704808 7158578 1593752..1594489 1 NC_011751.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1594489 pyrF 7158578 pyrF Escherichia coli UMN026 orotidine 5'-phosphate decarboxylase YP_002412327.1 1593752 D 585056 CDS YP_002412328.1 218704809 7157601 1594489..1594815 1 NC_011751.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1594815 yciH 7157601 yciH Escherichia coli UMN026 translation initiation factor Sui1 YP_002412328.1 1594489 D 585056 CDS YP_002412329.1 218704810 7158575 complement(1594941..1595159) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein; lipoprotein 1595159 osmB 7158575 osmB Escherichia coli UMN026 lipoprotein YP_002412329.1 1594941 R 585056 CDS YP_002412330.1 218704811 7157363 complement(1595428..1596177) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16451192; Product type r : regulator; DNA-binding transcriptional repressor 1596177 deoT 7157363 deoT Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002412330.1 1595428 R 585056 CDS YP_002412331.1 218704812 7156145 complement(1596267..1596482) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1596482 7156145 ECUMN_1588 Escherichia coli UMN026 hypothetical protein YP_002412331.1 1596267 R 585056 CDS YP_002412332.1 218704813 7154975 complement(1596587..1598572) 1 NC_011751.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1598572 gmr 7154975 gmr Escherichia coli UMN026 RNase II stability modulator YP_002412332.1 1596587 R 585056 CDS YP_002412333.1 218704814 7156591 complement(1598807..1600741) 1 NC_011751.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1600741 rnb 7156591 rnb Escherichia coli UMN026 exoribonuclease II YP_002412333.1 1598807 R 585056 CDS YP_002412334.1 218704815 7157707 complement(1600809..1601936) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amidase or amidotransferase 1601936 yciW 7157707 yciW Escherichia coli UMN026 putative amidase or amidotransferase YP_002412334.1 1600809 R 585056 CDS YP_002412335.1 218704816 7158585 complement(1602080..1602868) 1 NC_011751.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 1602868 fabI 7158585 fabI Escherichia coli UMN026 enoyl-(acyl carrier protein) reductase YP_002412335.1 1602080 R 585056 CDS YP_002412336.1 218704817 7156299 complement(1603038..1603205) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1603205 7156299 ECUMN_1593 Escherichia coli UMN026 hypothetical protein YP_002412336.1 1603038 R 585056 CDS YP_002412337.1 218704818 7154976 complement(1603252..1603617) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1603617 ycjD 7154976 ycjD Escherichia coli UMN026 hypothetical protein YP_002412337.1 1603252 R 585056 CDS YP_002412338.1 218704819 7158586 complement(1603685..1604491) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein transporter 1604491 sapF 7158586 sapF Escherichia coli UMN026 antimicrobial peptide ABC transporter ATP-binding protein transporter YP_002412338.1 1603685 R 585056 CDS YP_002412339.1 218704820 7157869 complement(1604493..1605485) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein 1605485 sapD 7157869 sapD Escherichia coli UMN026 antimicrobial peptide ABC transporter ATP-binding protein YP_002412339.1 1604493 R 585056 CDS YP_002412340.1 218704821 7157868 complement(1605485..1606375) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1606375 sapC 7157868 sapC Escherichia coli UMN026 antimicrobial peptide ABC transporter permease YP_002412340.1 1605485 R 585056 CDS YP_002412341.1 218704822 7157867 complement(1606362..1607327) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1607327 sapB 7157867 sapB Escherichia coli UMN026 antimicrobial peptide ABC transporter permease YP_002412341.1 1606362 R 585056 CDS YP_002412342.1 218704823 7157866 complement(1607324..1608967) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter periplasmic-binding protein 1608967 sapA 7157866 sapA Escherichia coli UMN026 antimicrobial peptide ABC transporter periplasmic-binding protein YP_002412342.1 1607324 R 585056 CDS YP_002412343.1 218704824 7157865 complement(1609010..1609210) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1609210 7157865 ECUMN_1600 Escherichia coli UMN026 hypothetical protein YP_002412343.1 1609010 R 585056 CDS YP_002412344.1 218704825 7154977 complement(1609280..1609525) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1609525 ymjA 7154977 ymjA Escherichia coli UMN026 hypothetical protein YP_002412344.1 1609280 R 585056 CDS YP_002412345.1 218704826 7159493 complement(1609659..1611044) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15590624; Product type t : transporter; putrescine importer 1611044 puuP 7159493 puuP Escherichia coli UMN026 putrescine importer YP_002412345.1 1609659 R 585056 CDS YP_002412346.1 218704827 7157593 complement(1611347..1612765) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15590624; Product type e : enzyme; gamma-Glu-putrescine synthase 1612765 puuA 7157593 puuA Escherichia coli UMN026 gamma-Glu-putrescine synthase YP_002412346.1 1611347 R 585056 CDS YP_002412347.1 218704828 7157588 1612977..1613741 1 NC_011751.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1613741 puuD 7157588 puuD Escherichia coli UMN026 gamma-glutamyl-gamma-aminobutyrate hydrolase YP_002412347.1 1612977 D 585056 CDS YP_002412348.1 218704829 7157591 1613768..1614325 1 NC_011751.1 regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1614325 puuR 7157591 puuR Escherichia coli UMN026 DNA-binding transcriptional repressor PuuR YP_002412348.1 1613768 D 585056 CDS YP_002412349.1 218704830 7157594 1614475..1615962 1 NC_011751.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1615962 puuC 7157594 puuC Escherichia coli UMN026 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase YP_002412349.1 1614475 D 585056 CDS YP_002412350.1 218704831 7157590 1615964..1617244 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150200, 15590624; Product type e : enzyme; gamma-Glu-putrescine oxidase 1617244 puuB 7157590 puuB Escherichia coli UMN026 gamma-Glu-putrescine oxidase YP_002412350.1 1615964 D 585056 CDS YP_002412351.1 218704832 7157589 1617282..1618547 1 NC_011751.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1618547 puuE 7157589 puuE Escherichia coli UMN026 4-aminobutyrate transaminase YP_002412351.1 1617282 D 585056 CDS YP_002412352.1 218704833 7157592 complement(1618667..1619644) 1 NC_011751.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1619644 pspF 7157592 pspF Escherichia coli UMN026 phage shock protein operon transcriptional activator YP_002412352.1 1618667 R 585056 CDS YP_002412353.1 218704834 7157555 1619811..1620479 1 NC_011751.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1620479 pspA 7157555 pspA Escherichia coli UMN026 phage shock protein PspA YP_002412353.1 1619811 D 585056 CDS YP_002412354.1 218704835 7157550 1620533..1620757 1 NC_011751.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1620757 pspB 7157550 pspB Escherichia coli UMN026 phage shock protein B YP_002412354.1 1620533 D 585056 CDS YP_002412355.1 218704836 7157551 1620757..1621116 1 NC_011751.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1621116 pspC 7157551 pspC Escherichia coli UMN026 DNA-binding transcriptional activator PspC YP_002412355.1 1620757 D 585056 CDS YP_002412356.1 218704837 7157552 1621125..1621346 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype; peripheral inner membrane phage-shock protein 1621346 pspD 7157552 pspD Escherichia coli UMN026 peripheral inner membrane phage-shock protein YP_002412356.1 1621125 D 585056 CDS YP_002412357.1 218704838 7157553 1621421..1621735 1 NC_011751.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1621735 pspE 7157553 pspE Escherichia coli UMN026 thiosulfate:cyanide sulfurtransferase YP_002412357.1 1621421 D 585056 CDS YP_002412358.1 218704839 7157554 1621854..1623251 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1623251 ycjX 7157554 ycjX Escherichia coli UMN026 hypothetical protein YP_002412358.1 1621854 D 585056 CDS YP_002412359.1 218704840 7158589 1623248..1624309 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1624309 ycjF 7158589 ycjF Escherichia coli UMN026 hypothetical protein YP_002412359.1 1623248 D 585056 CDS YP_002412360.1 218704841 7158587 1624457..1625998 1 NC_011751.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1625998 tyrR 7158587 tyrR Escherichia coli UMN026 DNA-binding transcriptional regulator TyrR YP_002412360.1 1624457 D 585056 CDS YP_002412361.1 218704842 7158150 complement(1626042..1626548) 1 NC_011751.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1626548 tpx 7158150 tpx Escherichia coli UMN026 thiol peroxidase YP_002412361.1 1626042 R 585056 CDS YP_002412362.1 218704843 7158101 1626667..1627632 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme; L-Ala-D/L-Glu epimerase 1627632 ycjG 7158101 ycjG Escherichia coli UMN026 L-Ala-D/L-Glu epimerase YP_002412362.1 1626667 D 585056 CDS YP_002412363.1 218704844 7158588 complement(1627607..1628395) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme; murein peptide amidase A 1628395 mpaA 7158588 mpaA Escherichia coli UMN026 murein peptide amidase A YP_002412363.1 1627607 R 585056 CDS YP_002412364.1 218704845 7157164 complement(1628626..1629264) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P) binding enzyme 1629264 ymjC 7157164 ymjC Escherichia coli UMN026 putative NAD(P) binding enzyme YP_002412364.1 1628626 R 585056 CDS YP_002412365.1 218704846 7159494 complement(1629335..1630267) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 1630267 ycjY 7159494 ycjY Escherichia coli UMN026 putative hydrolase YP_002412365.1 1629335 R 585056 CDS YP_002412366.1 218704847 7158590 1630393..1631292 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pr : putative regulator; putative nucleic acid-binding regulator 1631292 ycjZ 7158590 ycjZ Escherichia coli UMN026 putative nucleic acid-binding regulator YP_002412366.1 1630393 D 585056 CDS YP_002412367.1 218704848 7158591 1631629..1633242 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter; murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein 1633242 mppA 7158591 mppA Escherichia coli UMN026 murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) ABC transporter periplasmic-binding protein YP_002412367.1 1631629 D 585056 CDS YP_002412368.1 218704849 7157168 complement(1633293..1634324) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1634324 ynaI 7157168 ynaI Escherichia coli UMN026 hypothetical protein YP_002412368.1 1633293 R 585056 CDS YP_002412369.1 218704850 7159495 1634568..1634825 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1634825 ynaJ 7159495 ynaJ Escherichia coli UMN026 hypothetical protein YP_002412369.1 1634568 D 585056 CDS YP_002412370.1 218704851 7159496 complement(1634875..1635825) 1 NC_011751.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1635825 uspE 7159496 uspE Escherichia coli UMN026 universal stress protein UspE YP_002412370.1 1634875 R 585056 CDS YP_002412371.1 218704852 7158194 complement(1635977..1636729) 1 NC_011751.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1636729 fnr 7158194 fnr Escherichia coli UMN026 fumarate/nitrate reduction transcriptional regulator YP_002412371.1 1635977 R 585056 CDS YP_002412372.1 218704853 7156420 complement(1636924..1637439) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1637439 ogt 7156420 ogt Escherichia coli UMN026 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_002412372.1 1636924 R 585056 CDS YP_002412373.1 218704854 7157343 complement(1637450..1638976) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9829935, 2825131, 7567469; Product type t : transporter; putative aminobenzoyl-glutamate transporter 1638976 abgT 7157343 abgT Escherichia coli UMN026 putative aminobenzoyl-glutamate transporter YP_002412373.1 1637450 R 585056 CDS YP_002412374.1 218704855 7155669 complement(1638906..1639100) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1639100 7155669 ECUMN_1632 Escherichia coli UMN026 hypothetical protein YP_002412374.1 1638906 R 585056 CDS YP_002412375.1 218704856 7154978 complement(1639013..1640458) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9829935; Product type pe : putative enzyme; putative peptidase, aminobenzoyl-glutamate utilization protein 1640458 abgB 7154978 abgB Escherichia coli UMN026 putative peptidase, aminobenzoyl-glutamate utilization protein YP_002412375.1 1639013 R 585056 CDS YP_002412376.1 218704857 7155667 complement(1640458..1641768) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9829935; Product type pe : putative enzyme; putative peptidase, para-aminobenzoyl-glutamate utilization protein 1641768 abgA 7155667 abgA Escherichia coli UMN026 putative peptidase, para-aminobenzoyl-glutamate utilization protein YP_002412376.1 1640458 R 585056 CDS YP_002412377.1 218704858 7155666 1641944..1642852 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9829935; Product type r : regulator; putative DNA-binding transcriptional regulator 1642852 abgR 7155666 abgR Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412377.1 1641944 D 585056 CDS YP_002412378.1 218704859 7156870 1643182..1643745 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1643745 ydaL 7156870 ydaL Escherichia coli UMN026 hypothetical protein YP_002412378.1 1643182 D 585056 CDS YP_002412379.1 218704860 7158592 complement(1643766..1644998) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16045609; Product type pe : putative enzyme; putative diguanylate cyclase, GG[D/E]EF domain signalling protein 1644998 ydaM 7158592 ydaM Escherichia coli UMN026 putative diguanylate cyclase, GG[D/E]EF domain signalling protein YP_002412379.1 1643766 R 585056 CDS YP_002412380.1 218704861 7158593 1645253..1646236 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; zinc transporter 1646236 zntB 7158593 zntB Escherichia coli UMN026 zinc transporter YP_002412380.1 1645253 D 585056 CDS YP_002412381.1 218704862 7158594 1646512..1646685 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1646685 7158594 ECUMN_1639 Escherichia coli UMN026 hypothetical protein YP_002412381.1 1646512 D 585056 CDS YP_002412382.1 218704863 7155903 1646715..1648088 1 NC_011751.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1648088 dbpA 7155903 dbpA Escherichia coli UMN026 ATP-dependent RNA helicase DbpA YP_002412382.1 1646715 D 585056 CDS YP_002412383.1 218704864 7156112 complement(1648217..1649152) 1 NC_011751.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1649152 ydaO 7156112 ydaO Escherichia coli UMN026 C32 tRNA thiolase YP_002412383.1 1648217 R 585056 CDS YP_002412384.1 218704865 7158595 complement(1649328..1649762) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor; stress-induced protein, ATP-binding protein 1649762 uspF 7158595 uspF Escherichia coli UMN026 stress-induced protein, ATP-binding protein YP_002412384.1 1649328 R 585056 CDS YP_002412385.1 218704866 7158195 complement(1649903..1651036) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642192; Product type t : transporter; outer membrane pore protein N, non-specific 1651036 ompN 7158195 ompN Escherichia coli UMN026 outer membrane pore protein N, non-specific YP_002412385.1 1649903 R 585056 CDS YP_002412386.1 218704867 7157131 complement(1651398..1654922) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : putative enzyme; putative 2-oxoacid-flavodoxin 1654922 ydbK 7157131 ydbK Escherichia coli UMN026 putative 2-oxoacid-flavodoxin YP_002412386.1 1651398 R 585056 CDS YP_002412387.1 218704868 7158601 1655196..1655462 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1655462 ydbJ 7158601 ydbJ Escherichia coli UMN026 hypothetical protein YP_002412387.1 1655196 D 585056 CDS YP_002412388.1 218704869 7158600 complement(1655459..1655881) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12892888, 8349564, 9025293; Product type f : factor; heat-inducible protein 1655881 hslJ 7158600 hslJ Escherichia coli UMN026 heat-inducible protein YP_002412388.1 1655459 R 585056 CDS YP_002412389.1 218704870 7156720 complement(1655992..1656981) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme; fermentative D-lactate dehydrogenase 1656981 ldhA 7156720 ldhA Escherichia coli UMN026 fermentative D-lactate dehydrogenase YP_002412389.1 1655992 R 585056 CDS YP_002412390.1 218704871 7156937 1657189..1659828 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1659828 ydbH 7156937 ydbH Escherichia coli UMN026 hypothetical protein YP_002412390.1 1657189 D 585056 CDS YP_002412391.1 218704872 7158599 1659825..1660010 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 1660010 ynbE 7158599 ynbE Escherichia coli UMN026 putative lipoprotein YP_002412391.1 1659825 D 585056 CDS YP_002412392.1 218704873 7159501 1660018..1660341 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1660341 ydbL 7159501 ydbL Escherichia coli UMN026 hypothetical protein YP_002412392.1 1660018 D 585056 CDS YP_002412393.1 218704874 7158602 1660767..1666586 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative autotransported outer membrane protein involved in cell adhesion 1666586 ydbA 7158602 ydbA Escherichia coli UMN026 putative autotransported outer membrane protein involved in cell adhesion YP_002412393.1 1660767 D 585056 CDS YP_002412394.1 218704875 7158596 1666794..1667654 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1667654 ydbC 7158596 ydbC Escherichia coli UMN026 putative oxidoreductase YP_002412394.1 1666794 D 585056 CDS YP_002412395.1 218704876 7158597 1667718..1670024 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1670024 ydbD 7158597 ydbD Escherichia coli UMN026 hypothetical protein YP_002412395.1 1667718 D 585056 CDS YP_002412396.1 218704877 7158598 1670193..1670798 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1670798 ynbA 7158598 ynbA Escherichia coli UMN026 hypothetical protein YP_002412396.1 1670193 D 585056 CDS YP_002412397.1 218704878 7159497 1670798..1671694 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane associated CTP-phosphosubstrate transferase 1671694 ynbB 7159497 ynbB Escherichia coli UMN026 putative membrane associated CTP-phosphosubstrate transferase YP_002412397.1 1670798 D 585056 CDS YP_002412398.1 218704879 7159498 1671710..1673467 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 1673467 ynbC 7159498 ynbC Escherichia coli UMN026 putative hydrolase YP_002412398.1 1671710 D 585056 CDS YP_002412399.1 218704880 7159499 1673481..1674773 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane associated phosphatase 1674773 ynbD 7159499 ynbD Escherichia coli UMN026 putative membrane associated phosphatase YP_002412399.1 1673481 D 585056 CDS YP_002412400.1 218704881 7159500 complement(1674827..1675432) 1 NC_011751.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1675432 azoR 7159500 azoR Escherichia coli UMN026 azoreductase YP_002412400.1 1674827 R 585056 CDS YP_002412401.1 218704882 7155845 1675690..1679535 1 NC_011751.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1679535 hrpA 7155845 hrpA Escherichia coli UMN026 ATP-dependent RNA helicase HrpA YP_002412401.1 1675690 D 585056 CDS YP_002412402.1 218704883 7156712 complement(1679937..1680431) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1680431 7156712 ECUMN_1661 Escherichia coli UMN026 hypothetical protein YP_002412402.1 1679937 R 585056 CDS YP_002412403.1 218704884 7154980 1680821..1681621 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1681621 ydcF 7154980 ydcF Escherichia coli UMN026 hypothetical protein YP_002412403.1 1680821 D 585056 CDS YP_002412404.1 218704885 7158604 1681818..1683257 1 NC_011751.1 NAD-linked; aldehyde dehydrogenase A 1683257 aldA 7158604 aldA Escherichia coli UMN026 aldehyde dehydrogenase A YP_002412404.1 1681818 D 585056 CDS YP_002412405.1 218704886 7155722 complement(1683299..1684300) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase C 1684300 gapC 7155722 gapC Escherichia coli UMN026 glyceraldehyde-3-phosphate dehydrogenase C YP_002412405.1 1683299 R 585056 CDS YP_002412406.1 218704887 7156504 1684489..1685019 1 NC_011751.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1685019 cybB 7156504 cybB Escherichia coli UMN026 cytochrome b561 YP_002412406.1 1684489 D 585056 CDS YP_002412407.1 218704888 7157838 1685264..1685437 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1685437 ydcA 7157838 ydcA Escherichia coli UMN026 hypothetical protein YP_002412407.1 1685264 D 585056 CDS YP_002412408.1 218704889 7158603 complement(1685549..1685716) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type r : regulator; regulatory peptide 1685716 mokB 7158603 mokB Escherichia coli UMN026 regulatory peptide YP_002412408.1 1685549 R 585056 CDS YP_002412409.1 218704890 7157950 1686048..1687688 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90008892, 92390356, 93259131, 6374654; Product type r : regulator; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1687688 trg 7157950 trg Escherichia coli UMN026 methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor YP_002412409.1 1686048 D 585056 CDS YP_002412410.1 218704891 7158107 complement(1687727..1688650) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1688650 ydcI 7158107 ydcI Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412410.1 1687727 R 585056 CDS YP_002412411.1 218704892 7158606 1688867..1690210 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1690210 ydcJ 7158606 ydcJ Escherichia coli UMN026 hypothetical protein YP_002412411.1 1688867 D 585056 CDS YP_002412412.1 218704893 7158607 1690465..1692090 1 NC_011751.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1692090 mdoD 7158607 mdoD Escherichia coli UMN026 glucan biosynthesis protein D YP_002412412.1 1690465 D 585056 CDS YP_002412413.1 218704894 7157074 complement(1692011..1692214) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1692214 7157074 ECUMN_1673 Escherichia coli UMN026 hypothetical protein YP_002412413.1 1692011 R 585056 CDS YP_002412414.1 218704895 7154981 1692230..1692454 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1692454 ydcH 7154981 ydcH Escherichia coli UMN026 hypothetical protein YP_002412414.1 1692230 D 585056 CDS YP_002412415.1 218704896 7158605 1692517..1693056 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89364711; Product type e : enzyme; ribosomal-protein-L7/L12-serine acetyltransferase 1693056 rimL 7158605 rimL Escherichia coli UMN026 ribosomal-protein-L7/L12-serine acetyltransferase YP_002412415.1 1692517 D 585056 CDS YP_002412416.1 218704897 7157694 complement(1693048..1694028) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 1694028 ydcK 7157694 ydcK Escherichia coli UMN026 hypothetical protein YP_002412416.1 1693048 R 585056 CDS YP_002412417.1 218704898 7158608 1694152..1695144 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94222856, 2060788; Product type t : transporter; potassium-tellurite ethidium and proflavin transporter 1695144 tehA 7158608 tehA Escherichia coli UMN026 potassium-tellurite ethidium and proflavin transporter YP_002412417.1 1694152 D 585056 CDS YP_002412418.1 218704899 7158045 1695141..1695734 1 NC_011751.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1695734 tehB 7158045 tehB Escherichia coli UMN026 tellurite resistance protein TehB YP_002412418.1 1695141 D 585056 CDS YP_002412419.1 218704900 7158046 1696036..1696704 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 1696704 ydcL 7158046 ydcL Escherichia coli UMN026 putative lipoprotein YP_002412419.1 1696036 D 585056 CDS YP_002412420.1 218704901 7158609 complement(1696739..1698034) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1885518; Product type pt : putative transporter; putative benzoate transporter 1698034 ydcO 7158609 ydcO Escherichia coli UMN026 putative benzoate transporter YP_002412420.1 1696739 R 585056 CDS YP_002412421.1 218704902 7158613 1698003..1698539 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1698539 ydcN 7158613 ydcN Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412421.1 1698003 D 585056 CDS YP_002412422.1 218704903 7158612 1698612..1700573 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 1700573 ydcP 7158612 ydcP Escherichia coli UMN026 putative peptidase YP_002412422.1 1698612 D 585056 CDS YP_002412423.1 218704904 7158614 complement(1700665..1700895) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1700895 yncJ 7158614 yncJ Escherichia coli UMN026 hypothetical protein YP_002412423.1 1700665 R 585056 CDS YP_002412424.1 218704905 7159508 1701117..1701293 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1701293 yncN 7159508 yncN Escherichia coli UMN026 hypothetical protein YP_002412424.1 1701117 D 585056 CDS YP_002412425.1 218704906 7159509 1701318..1701755 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1701755 ydcQ 7159509 ydcQ Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412425.1 1701318 D 585056 CDS YP_002412426.1 218704907 7158615 1701834..1703240 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1703240 ydcR 7158615 ydcR Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412426.1 1701834 D 585056 CDS YP_002412427.1 218704908 7158616 1703485..1704630 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter periplasmic-binding protein 1704630 ydcS 7158616 ydcS Escherichia coli UMN026 putative spermidine/putrescine ABC transporter periplasmic-binding protein YP_002412427.1 1703485 D 585056 CDS YP_002412428.1 218704909 7158617 1704648..1705661 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter ATP-binding protein 1705661 ydcT 7158617 ydcT Escherichia coli UMN026 putative spermidine/putrescine ABC transporter ATP-binding protein YP_002412428.1 1704648 D 585056 CDS YP_002412429.1 218704910 7158618 1705662..1706603 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter permease 1706603 ydcU 7158618 ydcU Escherichia coli UMN026 putative spermidine/putrescine ABC transporter permease YP_002412429.1 1705662 D 585056 CDS YP_002412430.1 218704911 7158619 1706593..1707387 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative spermidine/putrescine ABC transporter permease 1707387 ydcV 7158619 ydcV Escherichia coli UMN026 putative spermidine/putrescine ABC transporter permease YP_002412430.1 1706593 D 585056 CDS YP_002412431.1 218704912 7158620 1707409..1708833 1 NC_011751.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1708833 ydcW 7158620 ydcW Escherichia coli UMN026 gamma-aminobutyraldehyde dehydrogenase YP_002412431.1 1707409 D 585056 CDS YP_002412432.1 218704913 7158621 1709056..1709865 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8257133, 11841212, 12771141; Product type pe : putative enzyme; putative acetyltransferase 1709865 7158621 ECUMN_1693 Escherichia coli UMN026 putative acetyltransferase YP_002412432.1 1709056 D 585056 CDS YP_002412433.1 218704914 7154982 1710482..1710730 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1710730 ydcX 7154982 ydcX Escherichia coli UMN026 hypothetical protein YP_002412433.1 1710482 D 585056 CDS YP_002412434.1 218704915 7158622 1710816..1711049 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1711049 ydcY 7158622 ydcY Escherichia coli UMN026 hypothetical protein YP_002412434.1 1710816 D 585056 CDS YP_002412435.1 218704916 7158623 complement(1711050..1711499) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1711499 ydcZ 7158623 ydcZ Escherichia coli UMN026 hypothetical protein YP_002412435.1 1711050 R 585056 CDS YP_002412436.1 218704917 7158624 complement(1711496..1712014) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 1712014 yncA 7158624 yncA Escherichia coli UMN026 putative acyltransferase YP_002412436.1 1711496 R 585056 CDS YP_002412437.1 218704918 7159502 1712195..1713232 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1713232 yncB 7159502 yncB Escherichia coli UMN026 putative oxidoreductase, Zn-dependent and NAD(P)-binding YP_002412437.1 1712195 D 585056 CDS YP_002412438.1 218704919 7159503 1713430..1714095 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11004173; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1714095 yncC 7159503 yncC Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412438.1 1713430 D 585056 CDS YP_002412439.1 218704920 7159504 complement(1714131..1716233) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor; putative iron outer membrane receptor 1716233 yncD 7159504 yncD Escherichia coli UMN026 putative iron outer membrane receptor YP_002412439.1 1714131 R 585056 CDS YP_002412440.1 218704921 7159505 1716475..1717536 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1717536 yncE 7159505 yncE Escherichia coli UMN026 hypothetical protein YP_002412440.1 1716475 D 585056 CDS YP_002412441.1 218704922 7159506 complement(1717649..1719148) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter; L-asparagine transporter 1719148 ansP 7159506 ansP Escherichia coli UMN026 L-asparagine transporter YP_002412441.1 1717649 R 585056 CDS YP_002412442.1 218704923 7155747 1719415..1720032 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glutathione S-transferase-like protein 1720032 yncG 7155747 yncG Escherichia coli UMN026 glutathione S-transferase-like protein YP_002412442.1 1719415 D 585056 CDS YP_002412443.1 218704924 7159507 1720572..1720856 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1720856 7159507 ECUMN_1704 Escherichia coli UMN026 hypothetical protein YP_002412443.1 1720572 D 585056 CDS YP_002412444.1 218704925 7154990 1720875..1723280 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative VgrG/E protein associated with Rhs elements 1723280 7154990 ECUMN_1705 Escherichia coli UMN026 putative VgrG/E protein associated with Rhs elements YP_002412444.1 1720875 D 585056 CDS YP_002412445.1 218704926 7154991 1723234..1724061 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative zinc-dependent metallopeptidase 1724061 7154991 ECUMN_1706 Escherichia coli UMN026 putative zinc-dependent metallopeptidase YP_002412445.1 1723234 D 585056 CDS YP_002412446.1 218704927 7154992 1724085..1724744 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1724744 7154992 ECUMN_1707 Escherichia coli UMN026 hypothetical protein YP_002412446.1 1724085 D 585056 CDS YP_002412447.1 218704928 7154993 1724725..1724907 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1724907 7154993 ECUMN_1708 Escherichia coli UMN026 hypothetical protein YP_002412447.1 1724725 D 585056 CDS YP_002412448.1 218704929 7159179 1725524..1726084 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1726084 7159179 ECUMN_1710 Escherichia coli UMN026 hypothetical protein YP_002412448.1 1725524 D 585056 CDS YP_002412449.1 218704930 7154995 1726444..1727079 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1727079 7154995 ECUMN_1711 Escherichia coli UMN026 hypothetical protein YP_002412449.1 1726444 D 585056 CDS YP_002412450.1 218704931 7154996 1727232..1727405 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1727405 7154996 ECUMN_1712 Escherichia coli UMN026 hypothetical protein YP_002412450.1 1727232 D 585056 CDS YP_002412451.1 218704932 7154997 complement(1727472..1728041) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1728041 yddH 7154997 yddH Escherichia coli UMN026 hypothetical protein YP_002412451.1 1727472 R 585056 CDS YP_002412452.1 218704933 7158629 1728216..1729061 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1729061 nhoA 7158629 nhoA Escherichia coli UMN026 N-hydroxyarylamine O-acetyltransferase YP_002412452.1 1728216 D 585056 CDS YP_002412453.1 218704934 7157274 1729133..1729663 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 1729663 7157274 ECUMN_1715 Escherichia coli UMN026 transposase ORF A, IS1397 YP_002412453.1 1729133 D 585056 CDS YP_002412454.1 218704935 7154998 1729768..1730490 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 1730490 7154998 ECUMN_1716 Escherichia coli UMN026 transposase ORF B, IS3 family, IS150 group YP_002412454.1 1729768 D 585056 CDS YP_002412455.1 218704936 7154999 complement(1730579..1731472) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673; hypothetical protein 1731472 yddE 7154999 yddE Escherichia coli UMN026 hypothetical protein YP_002412455.1 1730579 R 585056 CDS YP_002412456.1 218704937 7158627 complement(1731551..1732231) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme; nitrate reductase 2 subunit gamma 1732231 narV 7158627 narV Escherichia coli UMN026 nitrate reductase 2 subunit gamma YP_002412456.1 1731551 R 585056 CDS YP_002412457.1 218704938 7157256 complement(1732228..1732923) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410, 92186712; Product type f : factor; nitrate reductase 2 subunit delta (assembly subunit) 1732923 narW 7157256 narW Escherichia coli UMN026 nitrate reductase 2 subunit delta (assembly subunit) YP_002412457.1 1732228 R 585056 CDS YP_002412458.1 218704939 7157257 complement(1732923..1734467) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type c : carrier; nitrate reductase 2 subunit beta 1734467 narY 7157257 narY Escherichia coli UMN026 nitrate reductase 2 subunit beta YP_002412458.1 1732923 R 585056 CDS YP_002412459.1 218704940 7157259 complement(1734464..1738204) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme; nitrate reductase 2 subunit alpha 1738204 narZ 7157259 narZ Escherichia coli UMN026 nitrate reductase 2 subunit alpha YP_002412459.1 1734464 R 585056 CDS YP_002412460.1 218704941 7157260 complement(1738299..1739687) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95266795, 2233673; Product type t : transporter; nitrate/nitrite transporter 1739687 narU 7157260 narU Escherichia coli UMN026 nitrate/nitrite transporter YP_002412460.1 1738299 R 585056 CDS YP_002412461.1 218704942 7157255 complement(1739999..1741294) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1741294 7157255 ECUMN_1723 Escherichia coli UMN026 hypothetical protein YP_002412461.1 1739999 R 585056 CDS YP_002412462.1 218704943 7155000 complement(1741317..1742582) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1742582 7155000 ECUMN_1724 Escherichia coli UMN026 hypothetical protein YP_002412462.1 1741317 R 585056 CDS YP_002412463.1 218704944 7155001 complement(1742746..1743846) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; Outer membrane porin protein ompD 1743846 7155001 ECUMN_1725 Escherichia coli UMN026 Outer membrane porin protein ompD YP_002412463.1 1742746 R 585056 CDS YP_002412464.1 218704945 7155002 complement(1744105..1744929) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter; hypothetical protein 1744929 yddG 7155002 yddG Escherichia coli UMN026 hypothetical protein YP_002412464.1 1744105 R 585056 CDS YP_002412465.1 218704946 7158628 1745218..1748265 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-N subunit alpha, nitrate-inducible 1748265 fdnG 7158628 fdnG Escherichia coli UMN026 formate dehydrogenase-N subunit alpha, nitrate-inducible YP_002412465.1 1745218 D 585056 CDS YP_002412466.1 218704947 7156316 1748278..1749162 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier; formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible 1749162 fdnH 7156316 fdnH Escherichia coli UMN026 formate dehydrogenase-N, Fe-S subunit beta, nitrate-inducible YP_002412466.1 1748278 D 585056 CDS YP_002412467.1 218704948 7156317 1749155..1749808 1 NC_011751.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1749808 fdnI 7156317 fdnI Escherichia coli UMN026 formate dehydrogenase-N subunit gamma YP_002412467.1 1749155 D 585056 CDS YP_002412468.1 218704949 7158630 complement(1750320..1750598) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative plasmid maintenance system killer protein 1750598 7158630 ECUMN_1732 Escherichia coli UMN026 putative plasmid maintenance system killer protein YP_002412468.1 1750320 R 585056 CDS YP_002412469.1 218704950 7155003 complement(1750784..1751794) 1 NC_011751.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1751794 adhP 7155003 adhP Escherichia coli UMN026 alcohol dehydrogenase YP_002412469.1 1750784 R 585056 CDS YP_002412470.1 218704951 7155699 complement(1751928..1753625) 1 NC_011751.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1753625 sfcA 7155699 sfcA Escherichia coli UMN026 malate dehydrogenase YP_002412470.1 1751928 R 585056 CDS YP_002412471.1 218704952 7157903 complement(1754021..1754236) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor; biofilm-dependent modulation protein 1754236 bdm 7157903 bdm Escherichia coli UMN026 biofilm-dependent modulation protein YP_002412471.1 1754021 R 585056 CDS YP_002412472.1 218704953 7155866 1754581..1755012 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component; osmotically inducible, stress-inducible membrane protein 1755012 osmC 7155866 osmC Escherichia coli UMN026 osmotically inducible, stress-inducible membrane protein YP_002412472.1 1754581 D 585056 CDS YP_002412473.1 218704954 7157364 complement(1755068..1755994) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter ATP-binding protein 1755994 ddpF 7157364 ddpF Escherichia coli UMN026 D-ala-D-ala ABC transporter ATP-binding protein YP_002412473.1 1755068 R 585056 CDS YP_002412474.1 218704955 7156131 complement(1755987..1756973) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter ATP-binding protein 1756973 ddpD 7156131 ddpD Escherichia coli UMN026 D-ala-D-ala ABC transporter ATP-binding protein YP_002412474.1 1755987 R 585056 CDS YP_002412475.1 218704956 7156130 complement(1756970..1757866) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; ATP-dependent peptide transporter membrane subunit 1757866 ddpC 7156130 ddpC Escherichia coli UMN026 ATP-dependent peptide transporter membrane subunit YP_002412475.1 1756970 R 585056 CDS YP_002412476.1 218704957 7156129 complement(1757863..1758885) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-ala ABC transporter membrane protein 1758885 ddpB 7156129 ddpB Escherichia coli UMN026 D-ala-D-ala ABC transporter membrane protein YP_002412476.1 1757863 R 585056 CDS YP_002412477.1 218704958 7156128 complement(1758887..1760437) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99432174; Product type t : transporter; D-ala-D-a la ABC transporter periplasmic-binding protein 1760437 ddpA 7156128 ddpA Escherichia coli UMN026 D-ala-D-a la ABC transporter periplasmic-binding protein YP_002412477.1 1758887 R 585056 CDS YP_002412478.1 218704959 7156127 complement(1760451..1761032) 1 NC_011751.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase 1761032 ddpX 7156127 ddpX Escherichia coli UMN026 D-alanyl-D-alanine dipeptidase YP_002412478.1 1760451 R 585056 CDS YP_002412479.1 218704960 7156132 complement(1761290..1763689) 1 NC_011751.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1763689 dos 7156132 dos Escherichia coli UMN026 cAMP phosphodiesterase YP_002412479.1 1761290 R 585056 CDS YP_002412480.1 218704961 7156194 complement(1763714..1764757) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 1764757 yddV 7156194 yddV Escherichia coli UMN026 putative diguanylate cyclase YP_002412480.1 1763714 R 585056 CDS YP_002412481.1 218704962 7158631 complement(1765472..1766791) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein; putative lipoprotein 1766791 yddW 7158631 yddW Escherichia coli UMN026 putative lipoprotein YP_002412481.1 1765472 R 585056 CDS YP_002412482.1 218704963 7158632 complement(1766922..1768457) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter; glutamate:gamma-aminobutyric acid antiporter 1768457 gadC 7158632 gadC Escherichia coli UMN026 glutamate:gamma-aminobutyric acid antiporter YP_002412482.1 1766922 R 585056 CDS YP_002412483.1 218704964 7156488 complement(1768613..1770013) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme; glutamate decarboxylase B, PLP-dependent 1770013 gadB 7156488 gadB Escherichia coli UMN026 glutamate decarboxylase B, PLP-dependent YP_002412483.1 1768613 R 585056 CDS YP_002412484.1 218704965 7156487 complement(1770376..1773171) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1659611, 11514505; Product type pe : putative enzyme; putative membrane-associated peptidase 1773171 pqqL 7156487 pqqL Escherichia coli UMN026 putative membrane-associated peptidase YP_002412484.1 1770376 R 585056 CDS YP_002412485.1 218704966 7157515 complement(1773216..1775588) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative porin protein 1775588 yddB 7157515 yddB Escherichia coli UMN026 putative porin protein YP_002412485.1 1773216 R 585056 CDS YP_002412486.1 218704967 7158626 complement(1775626..1777311) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative multidrug ABC transporter permease/ATP-binding protein 1777311 yddA 7158626 yddA Escherichia coli UMN026 putative multidrug ABC transporter permease/ATP-binding protein YP_002412486.1 1775626 R 585056 CDS YP_002412487.1 218704968 7158625 complement(1777602..1778759) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pr : putative regulator; hypothetical protein 1778759 ydeM 7158625 ydeM Escherichia coli UMN026 hypothetical protein YP_002412487.1 1777602 R 585056 CDS YP_002412488.1 218704969 7158637 complement(1778811..1780493) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase 1780493 ydeN 7158637 ydeN Escherichia coli UMN026 putative sulfatase YP_002412488.1 1778811 R 585056 CDS YP_002412489.1 218704970 7158638 complement(1780896..1781657) 1 NC_011751.1 regulates the cellular response to acid resistance; transcriptional regulator YdeO 1781657 ydeO 7158638 ydeO Escherichia coli UMN026 transcriptional regulator YdeO YP_002412489.1 1780896 R 585056 CDS YP_002412490.1 218704971 7158639 complement(1781732..1781965) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1781965 7158639 ECUMN_1754 Escherichia coli UMN026 hypothetical protein YP_002412490.1 1781732 R 585056 CDS YP_002412491.1 218704972 7155004 complement(1782177..1784456) 1 NC_011751.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase 1784456 ydeP 7155004 ydeP Escherichia coli UMN026 putative oxidoreductase YP_002412491.1 1782177 R 585056 CDS YP_002412492.1 218704973 7158640 complement(1784789..1785703) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like exported adhesin protein 1785703 ydeQ 7158640 ydeQ Escherichia coli UMN026 putative fimbrial-like exported adhesin protein YP_002412492.1 1784789 R 585056 CDS YP_002412493.1 218704974 7158641 complement(1785762..1786265) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin exported protein 1786265 ydeR 7158641 ydeR Escherichia coli UMN026 putative fimbrial-like adhesin exported protein YP_002412493.1 1785762 R 585056 CDS YP_002412494.1 218704975 7158642 complement(1786278..1786808) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin exported protein 1786808 ydeS 7158642 ydeS Escherichia coli UMN026 putative fimbrial-like adhesin exported protein YP_002412494.1 1786278 R 585056 CDS YP_002412495.1 218704976 7158643 complement(1786822..1789473) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative fimbrial outer membrane usher protein 1789473 7158643 ECUMN_1759 Escherichia coli UMN026 putative fimbrial outer membrane usher protein YP_002412495.1 1786822 R 585056 CDS YP_002412496.1 218704977 7155005 complement(1789515..1790234) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type f : factor; Periplasmic chaperone 1790234 7155005 ECUMN_1760 Escherichia coli UMN026 Periplasmic chaperone YP_002412496.1 1789515 R 585056 CDS YP_002412497.1 218704978 7155006 complement(1790588..1791199) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative major fimbrial subunit FmlA 1791199 7155006 ECUMN_1761 Escherichia coli UMN026 putative major fimbrial subunit FmlA YP_002412497.1 1790588 R 585056 CDS YP_002412498.1 218704979 7155007 complement(1791585..1791839) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative HTH-type transcriptional regulator yqhC (fragment) 1791839 7155007 ECUMN_1762 Escherichia coli UMN026 putative HTH-type transcriptional regulator yqhC (fragment) YP_002412498.1 1791585 R 585056 CDS YP_002412499.1 218704980 7155008 complement(1792254..1793057) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carboxymuconolactone decarboxylase 1793057 7155008 ECUMN_1763 Escherichia coli UMN026 putative carboxymuconolactone decarboxylase YP_002412499.1 1792254 R 585056 CDS YP_002412500.1 218704981 7155009 complement(1793073..1793798) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative lipoprotein 1793798 7155009 ECUMN_1764 Escherichia coli UMN026 putative lipoprotein YP_002412500.1 1793073 R 585056 CDS YP_002412501.1 218704982 7155010 complement(1793914..1794933) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Aryl-alcohol dehydrogenase (NADP(+)) 1794933 7155010 ECUMN_1766 Escherichia coli UMN026 putative Aryl-alcohol dehydrogenase (NADP(+)) YP_002412501.1 1793914 R 585056 CDS YP_002412502.1 218704983 7155011 complement(1794936..1795508) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)H oxidoreductase 1795508 7155011 ECUMN_1767 Escherichia coli UMN026 putative NAD(P)H oxidoreductase YP_002412502.1 1794936 R 585056 CDS YP_002412503.1 218704984 7155012 complement(1795659..1795850) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1795850 7155012 ECUMN_1768 Escherichia coli UMN026 hypothetical protein YP_002412503.1 1795659 R 585056 CDS YP_002412504.1 218704985 7155013 complement(1795801..1796271) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1796271 7155013 ECUMN_1769 Escherichia coli UMN026 hypothetical protein YP_002412504.1 1795801 R 585056 CDS YP_002412505.1 218704986 7155014 complement(1796180..1796350) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1796350 7155014 ECUMN_1770 Escherichia coli UMN026 hypothetical protein YP_002412505.1 1796180 R 585056 CDS YP_002412506.1 218704987 7155015 complement(1796438..1797385) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Tas protein 1797385 7155015 ECUMN_1771 Escherichia coli UMN026 putative Tas protein YP_002412506.1 1796438 R 585056 CDS YP_002412507.1 218704988 7155016 complement(1797459..1798160) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1798160 7155016 ECUMN_1772 Escherichia coli UMN026 hypothetical protein YP_002412507.1 1797459 R 585056 CDS YP_002412508.1 218704989 7155017 complement(1798157..1798468) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1798468 7155017 ECUMN_1773 Escherichia coli UMN026 hypothetical protein YP_002412508.1 1798157 R 585056 CDS YP_002412509.1 218704990 7155018 1798605..1799504 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative LysR-family transcriptional regulator 1799504 7155018 ECUMN_1774 Escherichia coli UMN026 putative LysR-family transcriptional regulator YP_002412509.1 1798605 D 585056 CDS YP_002412510.1 218704991 7155019 complement(1799748..1799891) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1799891 7155019 ECUMN_1775 Escherichia coli UMN026 hypothetical protein YP_002412510.1 1799748 R 585056 CDS YP_002412511.1 218704992 7155020 complement(1799902..1801224) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765; Product type r : regulator; regulator with hipB 1801224 hipA 7155020 hipA Escherichia coli UMN026 regulator with hipB YP_002412511.1 1799902 R 585056 CDS YP_002412512.1 218704993 7156671 complement(1801224..1801490) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765, 8021189; Product type r : regulator; DNA-binding transcriptional regulator HipB 1801490 hipB 7156671 hipB Escherichia coli UMN026 DNA-binding transcriptional regulator HipB YP_002412512.1 1801224 R 585056 CDS YP_002412513.1 218704994 7156672 complement(1801701..1807121) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative lipoprotein/autotransporter domain-containing protein 1807121 7156672 ECUMN_1778 Escherichia coli UMN026 putative lipoprotein/autotransporter domain-containing protein YP_002412513.1 1801701 R 585056 CDS YP_002412514.1 218704995 7155021 complement(1807643..1809235) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15601708, 14622426; Product type e : enzyme; autoinducer-2 (AI-2) kinase 1809235 lsrK 7155021 lsrK Escherichia coli UMN026 autoinducer-2 (AI-2) kinase YP_002412514.1 1807643 R 585056 CDS YP_002412515.1 218704996 7157025 complement(1809314..1810267) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16321939, 15601708, 14622426; Product type r : regulator; DNA-binding transcriptional regulator 1810267 lsrR 7157025 lsrR Escherichia coli UMN026 DNA-binding transcriptional regulator YP_002412515.1 1809314 R 585056 CDS YP_002412516.1 218704997 7157026 1810516..1812051 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12657059, 11722742; Product type t : transporter; AI2 ABC transporter ATP-binding protein 1812051 ego 7157026 ego Escherichia coli UMN026 AI2 ABC transporter ATP-binding protein YP_002412516.1 1810516 D 585056 CDS YP_002412517.1 218704998 7156232 1812045..1813073 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1813073 lsrC 7156232 lsrC Escherichia coli UMN026 AI2 ABC transporter membrane protein YP_002412517.1 1812045 D 585056 CDS YP_002412518.1 218704999 7157021 1813073..1814065 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1814065 lsrD 7157021 lsrD Escherichia coli UMN026 AI2 ABC transporter membrane protein YP_002412518.1 1813073 D 585056 CDS YP_002412519.1 218705000 7157022 1814077..1815099 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter periplasmic-binding protein 1815099 lsrB 7157022 lsrB Escherichia coli UMN026 AI2 ABC transporter periplasmic-binding protein YP_002412519.1 1814077 D 585056 CDS YP_002412520.1 218705001 7157020 1815126..1816001 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aldolase 1816001 lsrF 7157020 lsrF Escherichia coli UMN026 aldolase YP_002412520.1 1815126 D 585056 CDS YP_002412521.1 218705002 7157023 1816025..1816315 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; autoinducer-2 (AI-2) modifying protein LsrG 1816315 lsrG 7157023 lsrG Escherichia coli UMN026 autoinducer-2 (AI-2) modifying protein LsrG YP_002412521.1 1816025 D 585056 CDS YP_002412522.1 218705003 7157024 1816372..1817130 1 NC_011751.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1817130 tam 7157024 tam Escherichia coli UMN026 trans-aconitate 2-methyltransferase YP_002412522.1 1816372 D 585056 CDS YP_002412523.1 218705004 7158021 complement(1817134..1818048) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1818048 yneE 7158021 yneE Escherichia coli UMN026 hypothetical protein YP_002412523.1 1817134 R 585056 CDS YP_002412524.1 218705005 7159510 complement(1818245..1819696) 1 NC_011751.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1819696 uxaB 7159510 uxaB Escherichia coli UMN026 altronate oxidoreductase YP_002412524.1 1818245 R 585056 CDS YP_002412525.1 218705006 7158204 complement(1819923..1821341) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated diguanylate cyclase (GGDEF domain) 1821341 yneF 7158204 yneF Escherichia coli UMN026 putative membrane-associated diguanylate cyclase (GGDEF domain) YP_002412525.1 1819923 R 585056 CDS YP_002412526.1 218705007 7159511 complement(1821480..1821839) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1821839 yneG 7159511 yneG Escherichia coli UMN026 hypothetical protein YP_002412526.1 1821480 R 585056 CDS YP_002412527.1 218705008 7159512 complement(1821839..1822765) 1 NC_011751.1 catalyzes the formation of glutamate from glutamine; glutaminase 1822765 yneH 7159512 yneH Escherichia coli UMN026 glutaminase YP_002412527.1 1821839 R 585056 CDS YP_002412528.1 218705009 7159513 complement(1822829..1824217) 1 NC_011751.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate semialdehyde dehydrogenase 1824217 yneI 7159513 yneI Escherichia coli UMN026 putative succinate semialdehyde dehydrogenase YP_002412528.1 1822829 R 585056 CDS YP_002412529.1 218705010 7159514 1824318..1825193 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1825193 yneJ 7159514 yneJ Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412529.1 1824318 D 585056 CDS YP_002412530.1 218705011 7159515 1825277..1826392 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1826392 yneK 7159515 yneK Escherichia coli UMN026 hypothetical protein YP_002412530.1 1825277 D 585056 CDS YP_002412531.1 218705012 7159516 1826542..1827732 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter; sugar efflux transporter 1827732 ydeA 7159516 ydeA Escherichia coli UMN026 sugar efflux transporter YP_002412531.1 1826542 D 585056 CDS YP_002412532.1 218705013 7158633 complement(1827757..1828422) 1 NC_011751.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1828422 marC 7158633 marC Escherichia coli UMN026 multiple drug resistance protein MarC YP_002412532.1 1827757 R 585056 CDS YP_002412533.1 218705014 7157062 1828634..1829068 1 NC_011751.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1829068 marR 7157062 marR Escherichia coli UMN026 DNA-binding transcriptional repressor MarR YP_002412533.1 1828634 D 585056 CDS YP_002412534.1 218705015 7157063 1829088..1829471 1 NC_011751.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1829471 marA 7157063 marA Escherichia coli UMN026 DNA-binding transcriptional activator MarA YP_002412534.1 1829088 D 585056 CDS YP_002412535.1 218705016 7157060 1829503..1829721 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8383113; hypothetical protein 1829721 marB 7157060 marB Escherichia coli UMN026 hypothetical protein YP_002412535.1 1829503 D 585056 CDS YP_002412536.1 218705017 7157061 complement(1829752..1830651) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter; O-acetylserine/cysteine export protein 1830651 eamA 7157061 eamA Escherichia coli UMN026 O-acetylserine/cysteine export protein YP_002412536.1 1829752 R 585056 CDS YP_002412537.1 218705018 7156218 1830846..1832033 1 NC_011751.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1832033 ydeE 7156218 ydeE Escherichia coli UMN026 putative MFS-type transporter YdeE YP_002412537.1 1830846 D 585056 CDS YP_002412538.1 218705019 7158634 complement(1832474..1833364) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1833364 ydeH 7158634 ydeH Escherichia coli UMN026 hypothetical protein YP_002412538.1 1832474 R 585056 CDS YP_002412539.1 218705020 7158635 complement(1833619..1834011) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1834011 ydeI 7158635 ydeI Escherichia coli UMN026 hypothetical protein YP_002412539.1 1833619 R 585056 CDS YP_002412540.1 218705021 7158636 complement(1834376..1836421) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme; dipeptidyl carboxypeptidase II 1836421 dcp 7158636 dcp Escherichia coli UMN026 dipeptidyl carboxypeptidase II YP_002412540.1 1834376 R 585056 CDS YP_002412541.1 218705022 7156115 1836558..1837304 1 NC_011751.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1837304 ydfG 7156115 ydfG Escherichia coli UMN026 3-hydroxy acid dehydrogenase YP_002412541.1 1836558 D 585056 CDS YP_002412542.1 218705023 7158646 1837393..1838079 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1838079 ydfH 7158646 ydfH Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412542.1 1837393 D 585056 CDS YP_002412543.1 218705024 7158647 1838256..1838459 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12084818; Product type pc : putative carrier; putative selenium carrying protein 1838459 ydfZ 7158647 ydfZ Escherichia coli UMN026 putative selenium carrying protein YP_002412543.1 1838256 D 585056 CDS YP_002412544.1 218705025 7158658 complement(1838495..1839955) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mannonate dehydrogenase 1839955 ydfI 7158658 ydfI Escherichia coli UMN026 putative mannonate dehydrogenase YP_002412544.1 1838495 R 585056 CDS YP_002412545.1 218705026 7158648 complement(1840045..1841328) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 1841328 ydfJ 7158648 ydfJ Escherichia coli UMN026 putative transporter YP_002412545.1 1840045 R 585056 CDS YP_002412546.1 218705027 7158649 1842081..1842347 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative DNA-binding transcriptional regulator; Qin prophage 1842347 ydfK 7158649 ydfK Escherichia coli UMN026 putative DNA-binding transcriptional regulator; Qin prophage YP_002412546.1 1842081 D 585056 CDS YP_002412547.1 218705028 7158650 1842664..1843254 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14687564; Product type pe : putative enzyme; putative site-specific recombinase; DNA invertase; Rac prophage 1843254 pinR 7158650 pinR Escherichia coli UMN026 putative site-specific recombinase; DNA invertase; Rac prophage YP_002412547.1 1842664 D 585056 CDS YP_002412548.1 218705029 7157467 complement(1843352..1843927) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative tail fiber chaperone; Qin prophage 1843927 tfaQ 7157467 tfaQ Escherichia coli UMN026 putative tail fiber chaperone; Qin prophage YP_002412548.1 1843352 R 585056 CDS YP_002412549.1 218705030 7158050 complement(1843927..1846848) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber protein 1846848 7158050 ECUMN_1814 Escherichia coli UMN026 putative tail fiber protein YP_002412549.1 1843927 R 585056 CDS YP_002412550.1 218705031 7155022 complement(1846907..1847506) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Lom-like outer membrane protein of phage origin 1847506 7155022 ECUMN_1815 Escherichia coli UMN026 putative Lom-like outer membrane protein of phage origin YP_002412550.1 1846907 R 585056 CDS YP_002412551.1 218705032 7155023 complement(1847573..1850971) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J 1850971 7155023 ECUMN_1816 Escherichia coli UMN026 Host specificity protein J YP_002412551.1 1847573 R 585056 CDS YP_002412552.1 218705033 7155024 complement(1851032..1851679) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Tail assembly protein I 1851679 7155024 ECUMN_1817 Escherichia coli UMN026 Tail assembly protein I YP_002412552.1 1851032 R 585056 CDS YP_002412553.1 218705034 7155025 complement(1851577..1852329) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail fiber component K of prophage 1852329 7155025 ECUMN_1818 Escherichia coli UMN026 putative tail fiber component K of prophage YP_002412553.1 1851577 R 585056 CDS YP_002412554.1 218705035 7155026 complement(1852326..1853024) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 1853024 7155026 ECUMN_1819 Escherichia coli UMN026 Minor tail protein L YP_002412554.1 1852326 R 585056 CDS YP_002412555.1 218705036 7155027 complement(1853034..1853363) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 1853363 7155027 ECUMN_1820 Escherichia coli UMN026 Minor tail protein M YP_002412555.1 1853034 R 585056 CDS YP_002412556.1 218705037 7155028 complement(1853363..1856458) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative tail length tape measure protein 1856458 7155028 ECUMN_1821 Escherichia coli UMN026 putative tail length tape measure protein YP_002412556.1 1853363 R 585056 CDS YP_002412557.1 218705038 7155029 complement(1856400..1856729) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative minor tail protein T of putative prophage 1856729 7155029 ECUMN_1822 Escherichia coli UMN026 putative minor tail protein T of putative prophage YP_002412557.1 1856400 R 585056 CDS YP_002412558.1 218705039 7155030 complement(1856738..1857166) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative minor tail component of putative prophage 1857166 7155030 ECUMN_1823 Escherichia coli UMN026 putative minor tail component of putative prophage YP_002412558.1 1856738 R 585056 CDS YP_002412559.1 218705040 7155031 complement(1857185..1857934) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 1857934 7155031 ECUMN_1824 Escherichia coli UMN026 Major tail protein V YP_002412559.1 1857185 R 585056 CDS YP_002412560.1 218705041 7155032 complement(1857940..1858353) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 1858353 7155032 ECUMN_1825 Escherichia coli UMN026 Minor tail protein U YP_002412560.1 1857940 R 585056 CDS YP_002412561.1 218705042 7155033 complement(1858338..1858916) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GPZ) of prophage 1858916 7155033 ECUMN_1826 Escherichia coli UMN026 Minor tail protein Z (GPZ) of prophage YP_002412561.1 1858338 R 585056 CDS YP_002412562.1 218705043 7155034 complement(1858928..1859203) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1859203 7155034 ECUMN_1827 Escherichia coli UMN026 hypothetical protein YP_002412562.1 1858928 R 585056 CDS YP_002412563.1 218705044 7155035 complement(1859196..1859564) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1859564 7155035 ECUMN_1828 Escherichia coli UMN026 hypothetical protein YP_002412563.1 1859196 R 585056 CDS YP_002412564.1 218705045 7155036 complement(1859606..1861726) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) 1861726 7155036 ECUMN_1829 Escherichia coli UMN026 putative ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) YP_002412564.1 1859606 R 585056 CDS YP_002412565.1 218705046 7155037 complement(1861578..1863158) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative portal protein 1863158 7155037 ECUMN_1830 Escherichia coli UMN026 putative portal protein YP_002412565.1 1861578 R 585056 CDS YP_002412566.1 218705047 7155038 complement(1863086..1863304) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1863304 7155038 ECUMN_1831 Escherichia coli UMN026 hypothetical protein YP_002412566.1 1863086 R 585056 CDS YP_002412567.1 218705048 7155039 complement(1863295..1865397) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative DNA packaging protein 1865397 7155039 ECUMN_1832 Escherichia coli UMN026 putative DNA packaging protein YP_002412567.1 1863295 R 585056 CDS YP_002412568.1 218705049 7155040 complement(1865397..1865891) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1865891 7155040 ECUMN_1833 Escherichia coli UMN026 hypothetical protein YP_002412568.1 1865397 R 585056 CDS YP_002412569.1 218705050 7155041 complement(1866454..1866660) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1866660 ybcW 7155041 ybcW Escherichia coli UMN026 hypothetical protein YP_002412569.1 1866454 R 585056 CDS YP_002412570.1 218705051 7158388 1866946..1867371 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1867371 ybcV 7158388 ybcV Escherichia coli UMN026 hypothetical protein YP_002412570.1 1866946 D 585056 CDS YP_002412571.1 218705052 7158387 complement(1867523..1867696) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21429224; Product type h : extrachromosomal origin; hypothetical protein 1867696 gnsB 7158387 gnsB Escherichia coli UMN026 hypothetical protein YP_002412571.1 1867523 R 585056 CDS YP_002412572.1 218705053 7156594 complement(1867868..1868140) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1868140 7156594 ECUMN_1838 Escherichia coli UMN026 hypothetical protein YP_002412572.1 1867868 R 585056 CDS YP_002412573.1 218705054 7155042 complement(1868370..1868582) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 1868582 cspI 7155042 cspI Escherichia coli UMN026 cold shock protein; Qin prophage YP_002412573.1 1868370 R 585056 CDS YP_002412574.1 218705055 7156042 complement(1868946..1869443) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1869443 ydfP 7156042 ydfP Escherichia coli UMN026 hypothetical protein YP_002412574.1 1868946 R 585056 CDS YP_002412575.1 218705056 7158651 complement(1869440..1869973) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated lysozyme; Qin prophage 1869973 ydfQ 7158651 ydfQ Escherichia coli UMN026 putative membrane-associated lysozyme; Qin prophage YP_002412575.1 1869440 R 585056 CDS YP_002412576.1 218705057 7158653 complement(1869970..1870257) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1870257 ydfR 7158653 ydfR Escherichia coli UMN026 hypothetical protein YP_002412576.1 1869970 R 585056 CDS YP_002412577.1 218705058 7158654 complement(1870286..1870501) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative S lysis protein; Qin prophage 1870501 essQ 7158654 essQ Escherichia coli UMN026 putative S lysis protein; Qin prophage YP_002412577.1 1870286 R 585056 CDS YP_002412578.1 218705059 7156272 complement(1871255..1871470) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293754, 94293756, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 1871470 cspB 7156272 cspB Escherichia coli UMN026 cold shock protein; Qin prophage YP_002412578.1 1871255 R 585056 CDS YP_002412579.1 218705060 7156035 1871771..1871983 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 8022261, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 1871983 cspF 7156035 cspF Escherichia coli UMN026 cold shock protein; Qin prophage YP_002412579.1 1871771 D 585056 CDS YP_002412580.1 218705061 7156039 complement(1872405..1873157) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative antitermination protein Q; Qin prophage 1873157 ydfT 7156039 ydfT Escherichia coli UMN026 putative antitermination protein Q; Qin prophage YP_002412580.1 1872405 R 585056 CDS YP_002412581.1 218705062 7158655 complement(1873171..1874220) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1874220 ydfU 7158655 ydfU Escherichia coli UMN026 hypothetical protein YP_002412581.1 1873171 R 585056 CDS YP_002412582.1 218705063 7158657 complement(1874567..1874818) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2990907; Product type h : extrachromosomal origin; hypothetical protein 1874818 rem 7158657 rem Escherichia coli UMN026 hypothetical protein YP_002412582.1 1874567 R 585056 CDS YP_002412583.1 218705064 7157651 complement(1875406..1875609) 1 NC_011751.1 hypothetical protein 1875609 7157651 ECUMN_1849 Escherichia coli UMN026 hypothetical protein YP_002412583.1 1875406 R 585056 CDS YP_002412584.1 218705065 7155043 1875865..1877652 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1877652 7155043 ECUMN_1850 Escherichia coli UMN026 hypothetical protein YP_002412584.1 1875865 D 585056 CDS YP_002412585.1 218705066 7155044 complement(1877871..1878272) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1878272 7155044 ECUMN_1851 Escherichia coli UMN026 hypothetical protein YP_002412585.1 1877871 R 585056 CDS YP_002412586.1 218705067 7155045 complement(1878313..1879332) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1879332 7155045 ECUMN_1852 Escherichia coli UMN026 hypothetical protein YP_002412586.1 1878313 R 585056 CDS YP_002412587.1 218705068 7155046 complement(1879259..1879780) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1879780 7155046 ECUMN_1853 Escherichia coli UMN026 hypothetical protein YP_002412587.1 1879259 R 585056 CDS YP_002412588.1 218705069 7155047 complement(1879764..1880018) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA-binding transcriptional regulator DicC 1880018 7155047 ECUMN_1854 Escherichia coli UMN026 DNA-binding transcriptional regulator DicC YP_002412588.1 1879764 R 585056 CDS YP_002412589.1 218705070 7155048 1880018..1880476 1 NC_011751.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1880476 dicA 7155048 dicA Escherichia coli UMN026 transcriptional repressor DicA YP_002412589.1 1880018 D 585056 CDS YP_002412590.1 218705071 7156162 1880513..1880824 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1880824 7156162 ECUMN_1856 Escherichia coli UMN026 hypothetical protein YP_002412590.1 1880513 D 585056 CDS YP_002412591.1 218705072 7155049 1880784..1881401 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1881401 7155049 ECUMN_1857 Escherichia coli UMN026 hypothetical protein YP_002412591.1 1880784 D 585056 CDS YP_002412592.1 218705073 7156165 1881783..1882076 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative regulator of cell division encoded by prophage 1882076 7156165 ECUMN_1859 Escherichia coli UMN026 putative regulator of cell division encoded by prophage YP_002412592.1 1881783 D 585056 CDS YP_002412593.1 218705074 7155051 1882073..1882264 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 1882264 ydfD 7155051 ydfD Escherichia coli UMN026 hypothetical protein YP_002412593.1 1882073 D 585056 CDS YP_002412594.1 218705075 7158645 1882358..1884829 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative exonuclease from phage origin 1884829 7158645 ECUMN_1861 Escherichia coli UMN026 putative exonuclease from phage origin YP_002412594.1 1882358 D 585056 CDS YP_002412595.1 218705076 7155052 1884902..1885153 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage excisionase 1885153 xis 7155052 xis Escherichia coli UMN026 prophage excisionase YP_002412595.1 1884902 D 585056 CDS YP_002412596.1 218705077 7158248 1885173..1886468 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative defective integrase; Qin prophage 1886468 intQ 7158248 intQ Escherichia coli UMN026 putative defective integrase; Qin prophage YP_002412596.1 1885173 D 585056 CDS YP_002412597.1 218705078 7156845 complement(1886488..1886598) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1886598 ynfP 7156845 ynfP Escherichia coli UMN026 hypothetical protein YP_002412597.1 1886488 R 585056 CDS YP_002412598.1 218705079 7159530 complement(1886656..1887675) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : putative enzyme; putative dehydrogenase 1887675 rspB 7159530 rspB Escherichia coli UMN026 putative dehydrogenase YP_002412598.1 1886656 R 585056 CDS YP_002412599.1 218705080 7157800 complement(1887687..1888901) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme; putative enolase/dehydratase 1888901 rspA 7157800 rspA Escherichia coli UMN026 putative enolase/dehydratase YP_002412599.1 1887687 R 585056 CDS YP_002412600.1 218705081 7157799 complement(1889107..1889433) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1889433 ynfA 7157799 ynfA Escherichia coli UMN026 hypothetical protein YP_002412600.1 1889107 R 585056 CDS YP_002412601.1 218705082 7159517 1889568..1889909 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1889909 ynfB 7159517 ynfB Escherichia coli UMN026 hypothetical protein YP_002412601.1 1889568 D 585056 CDS YP_002412602.1 218705083 7159518 1889944..1890504 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme; spermidine N1-acetyltransferase 1890504 speG 7159518 speG Escherichia coli UMN026 spermidine N1-acetyltransferase YP_002412602.1 1889944 D 585056 CDS YP_002412603.1 218705084 7157962 complement(1890507..1891217) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1891217 ynfC 7157962 ynfC Escherichia coli UMN026 hypothetical protein YP_002412603.1 1890507 R 585056 CDS YP_002412604.1 218705085 7159519 1891325..1891630 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; hypothetical protein 1891630 ynfD 7159519 ynfD Escherichia coli UMN026 hypothetical protein YP_002412604.1 1891325 D 585056 CDS YP_002412605.1 218705086 7159520 1891829..1894255 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme; oxidoreductase subunit 1894255 ynfE 7159520 ynfE Escherichia coli UMN026 oxidoreductase subunit YP_002412605.1 1891829 D 585056 CDS YP_002412606.1 218705087 7159521 1894316..1896739 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme; oxidoreductase subunit 1896739 ynfF 7159521 ynfF Escherichia coli UMN026 oxidoreductase subunit YP_002412606.1 1894316 D 585056 CDS YP_002412607.1 218705088 7159522 1896750..1897367 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type c : carrier; oxidoreductase, Fe-S subunit 1897367 ynfG 7159522 ynfG Escherichia coli UMN026 oxidoreductase, Fe-S subunit YP_002412607.1 1896750 D 585056 CDS YP_002412608.1 218705089 7159523 1897369..1898223 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type m : membrane component; oxidoreductase, membrane subunit 1898223 ynfH 7159523 ynfH Escherichia coli UMN026 oxidoreductase, membrane subunit YP_002412608.1 1897369 D 585056 CDS YP_002412609.1 218705090 7159524 1898266..1898880 1 NC_011751.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1898880 dmsD 7159524 dmsD Escherichia coli UMN026 twin-argninine leader-binding protein DmsD YP_002412609.1 1898266 D 585056 CDS YP_002412610.1 218705091 7156182 1899074..1900330 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12384697; Product type pt : putative transporter; putative voltage-gated ClC-type chloride channel ClcB 1900330 clcB 7156182 clcB Escherichia coli UMN026 putative voltage-gated ClC-type chloride channel ClcB YP_002412610.1 1899074 D 585056 CDS YP_002412611.1 218705092 7155976 complement(1900283..1900978) 1 NC_011751.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase 1900978 ynfK 7155976 ynfK Escherichia coli UMN026 putative dithiobiotin synthetase YP_002412611.1 1900283 R 585056 CDS YP_002412612.1 218705093 7159525 complement(1901103..1902323) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator; DNA-binding transcriptional repressor 1902323 dgsA 7159525 dgsA Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002412612.1 1901103 R 585056 CDS YP_002412613.1 218705094 7156154 complement(1902458..1903351) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1903351 ynfL 7156154 ynfL Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412613.1 1902458 R 585056 CDS YP_002412614.1 218705095 7159526 1903458..1904711 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 1904711 ynfM 7159526 ynfM Escherichia coli UMN026 putative MFS superfamily transporter YP_002412614.1 1903458 D 585056 CDS YP_002412615.1 218705096 7159527 1905135..1905443 1 NC_011751.1 required for growth and survival under moderately acid conditions; acid shock protein 1905443 asr 7159527 asr Escherichia coli UMN026 acid shock protein YP_002412615.1 1905135 D 585056 CDS YP_002412616.1 218705097 7155820 1905719..1906540 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported metallopeptidase 1906540 ydgD 7155820 ydgD Escherichia coli UMN026 putative exported metallopeptidase YP_002412616.1 1905719 D 585056 CDS YP_002412617.1 218705098 7158661 complement(1906579..1906908) 1 NC_011751.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 1906908 mdtI 7158661 mdtI Escherichia coli UMN026 multidrug efflux system protein MdtI YP_002412617.1 1906579 R 585056 CDS YP_002412618.1 218705099 7157086 complement(1907089..1907265) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 1907265 7157086 ECUMN_1886 Escherichia coli UMN026 hypothetical protein YP_002412618.1 1907089 R 585056 CDS YP_002412619.1 218705100 7155053 1907125..1908141 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 1908141 insH 7155053 insH Escherichia coli UMN026 IS5 transposase and trans-activator; CP4-44 prophage YP_002412619.1 1907125 D 585056 CDS YP_002412620.1 218705101 7157087 1908871..1909905 1 NC_011751.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1909905 tqsA 7157087 tqsA Escherichia coli UMN026 putative transport protein YP_002412620.1 1908871 D 585056 CDS YP_002412621.1 218705102 7158662 complement(1909930..1911318) 1 NC_011751.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1911318 pntB 7158662 pntB Escherichia coli UMN026 pyridine nucleotide transhydrogenase YP_002412621.1 1909930 R 585056 CDS YP_002412622.1 218705103 7157482 complement(1911329..1912861) 1 NC_011751.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1912861 pntA 7157482 pntA Escherichia coli UMN026 NAD(P) transhydrogenase subunit alpha YP_002412622.1 1911329 R 585056 CDS YP_002412623.1 218705104 7157481 1913385..1914329 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1914329 ydgH 7157481 ydgH Escherichia coli UMN026 hypothetical protein YP_002412623.1 1913385 D 585056 CDS YP_002412624.1 218705105 7158663 1914515..1915897 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : putative transporter; putative arginine/ornithine antiporter transporter 1915897 ydgI 7158663 ydgI Escherichia coli UMN026 putative arginine/ornithine antiporter transporter YP_002412624.1 1914515 D 585056 CDS YP_002412625.1 218705106 7158664 1915934..1916656 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme; short chain dehydrogenase 1916656 folM 7158664 folM Escherichia coli UMN026 short chain dehydrogenase YP_002412625.1 1915934 D 585056 CDS YP_002412626.1 218705107 7156429 complement(1916653..1916988) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1916988 ydgC 7156429 ydgC Escherichia coli UMN026 hypothetical protein YP_002412626.1 1916653 R 585056 CDS YP_002412627.1 218705108 7158660 1917108..1917836 1 NC_011751.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1917836 rstA 7158660 rstA Escherichia coli UMN026 DNA-binding transcriptional regulator RstA YP_002412627.1 1917108 D 585056 CDS YP_002412628.1 218705109 7157803 1917840..1919141 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator; sensor protein RstB 1919141 rstB 7157803 rstB Escherichia coli UMN026 sensor protein RstB YP_002412628.1 1917840 D 585056 CDS YP_002412629.1 218705110 7157804 1919217..1920146 1 NC_011751.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1920146 tus 7157804 tus Escherichia coli UMN026 DNA replication terminus site-binding protein YP_002412629.1 1919217 D 585056 CDS YP_002412630.1 218705111 7158141 complement(1920143..1921546) 1 NC_011751.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1921546 fumC 7158141 fumC Escherichia coli UMN026 fumarate hydratase YP_002412630.1 1920143 R 585056 CDS YP_002412631.1 218705112 7156478 complement(1921689..1923335) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme; fumarate hydratase 1923335 fumA 7156478 fumA Escherichia coli UMN026 fumarate hydratase YP_002412631.1 1921689 R 585056 CDS YP_002412632.1 218705113 7156476 1923534..1924709 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme; mannose-6-phosphate isomerase 1924709 manA 7156476 manA Escherichia coli UMN026 mannose-6-phosphate isomerase YP_002412632.1 1923534 D 585056 CDS YP_002412633.1 218705114 7157054 1924810..1926318 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1926318 ydgA 7157054 ydgA Escherichia coli UMN026 hypothetical protein YP_002412633.1 1924810 D 585056 CDS YP_002412634.1 218705115 7158659 complement(1926363..1927628) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15774881; Product type t : transporter; putative outer membrane porin protein 1927628 uidC 7158659 uidC Escherichia coli UMN026 putative outer membrane porin protein YP_002412634.1 1926363 R 585056 CDS YP_002412635.1 218705116 7158176 complement(1927667..1929040) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3534890; Product type t : transporter; glucuronide transporter 1929040 uidB 7158176 uidB Escherichia coli UMN026 glucuronide transporter YP_002412635.1 1927667 R 585056 CDS YP_002412636.1 218705117 7158175 complement(1929037..1930848) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87041472, 88038341, 2103475, 8125312; Product type e : enzyme; beta-D-glucuronidase 1930848 uidA 7158175 uidA Escherichia coli UMN026 beta-D-glucuronidase YP_002412636.1 1929037 R 585056 CDS YP_002412637.1 218705118 7158174 complement(1931239..1931829) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88038341, 2823062, 3934044, 11115104; Product type r : regulator; DNA-binding transcriptional repressor 1931829 uidR 7158174 uidR Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002412637.1 1931239 R 585056 CDS YP_002412638.1 218705119 7158177 complement(1932050..1932817) 1 NC_011751.1 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1932817 hdhA 7158177 hdhA Escherichia coli UMN026 7-alpha-hydroxysteroid dehydrogenase YP_002412638.1 1932050 R 585056 CDS YP_002412639.1 218705120 7156648 complement(1932929..1933957) 1 NC_011751.1 regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI 1933957 malI 7156648 malI Escherichia coli UMN026 DNA-binding transcriptional repressor MalI YP_002412639.1 1932929 R 585056 CDS YP_002412640.1 218705121 7157044 1934132..1935724 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1935724 malX 7157044 malX Escherichia coli UMN026 bifunctional PTS system maltose and glucose-specific transporter subunits IICB YP_002412640.1 1934132 D 585056 CDS YP_002412641.1 218705122 7157051 1935734..1936906 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20164451, 7665481, 91310596; Product type e : enzyme; bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon 1936906 malY 7157051 malY Escherichia coli UMN026 bifunctional beta-cystathionase, PLP-dependent and regulator of maltose regulon YP_002412641.1 1935734 D 585056 CDS YP_002412642.1 218705123 7157052 1937010..1938011 1 NC_011751.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1938011 add 7157052 add Escherichia coli UMN026 adenosine deaminase YP_002412642.1 1937010 D 585056 CDS YP_002412643.1 218705124 7155696 complement(1938047..1939087) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1939087 ydgJ 7155696 ydgJ Escherichia coli UMN026 putative oxidoreductase YP_002412643.1 1938047 R 585056 CDS YP_002412644.1 218705125 7158665 1939255..1939455 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392465, 10931331; Product type m : membrane component; beta-lactam resistance membrane protein 1939455 blr 7158665 blr Escherichia coli UMN026 beta-lactam resistance membrane protein YP_002412644.1 1939255 D 585056 CDS YP_002412645.1 218705126 7155888 1939728..1939943 1 NC_011751.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1939943 ydgT 7155888 ydgT Escherichia coli UMN026 oriC-binding nucleoid-associated protein YP_002412645.1 1939728 D 585056 CDS YP_002412646.1 218705127 7158668 1940029..1940469 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1940469 ydgK 7158668 ydgK Escherichia coli UMN026 hypothetical protein YP_002412646.1 1940029 D 585056 CDS YP_002412647.1 218705128 7158666 1940546..1941127 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : putative membrane component; Na(+)-translocating NADH-quinone reductase subunit E 1941127 rsxA 7158666 rsxA Escherichia coli UMN026 Na(+)-translocating NADH-quinone reductase subunit E YP_002412647.1 1940546 D 585056 CDS YP_002412648.1 218705129 7157806 1941127..1941705 1 NC_011751.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1941705 rsxB 7157806 rsxB Escherichia coli UMN026 electron transport complex protein RnfB YP_002412648.1 1941127 D 585056 CDS YP_002412649.1 218705130 7157807 1941698..1943920 1 NC_011751.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1943920 rsxC 7157807 rsxC Escherichia coli UMN026 electron transport complex protein RnfC YP_002412649.1 1941698 D 585056 CDS YP_002412650.1 218705131 7157808 1943921..1944979 1 NC_011751.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1944979 rnfD 7157808 rnfD Escherichia coli UMN026 electron transport complex protein RnfD YP_002412650.1 1943921 D 585056 CDS YP_002412651.1 218705132 7157809 1944983..1945603 1 NC_011751.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1945603 rsxG 7157809 rsxG Escherichia coli UMN026 electron transport complex protein RnfG YP_002412651.1 1944983 D 585056 CDS YP_002412652.1 218705133 7157811 1945607..1946302 1 NC_011751.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1946302 rsxE 7157811 rsxE Escherichia coli UMN026 electron transport complex RsxE subunit YP_002412652.1 1945607 D 585056 CDS YP_002412653.1 218705134 7157810 1946302..1946937 1 NC_011751.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1946937 nth 7157810 nth Escherichia coli UMN026 endonuclease III YP_002412653.1 1946302 D 585056 CDS YP_002412654.1 218705135 7157315 1947548..1949050 1 NC_011751.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1949050 tppB 7157315 tppB Escherichia coli UMN026 putative tripeptide transporter permease YP_002412654.1 1947548 D 585056 CDS YP_002412655.1 218705136 7158667 1949156..1949761 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme; glutathionine S-transferase 1949761 gst 7158667 gst Escherichia coli UMN026 glutathionine S-transferase YP_002412655.1 1949156 D 585056 CDS YP_002412656.1 218705137 7156621 complement(1949805..1950668) 1 NC_011751.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1950668 pdxY 7156621 pdxY Escherichia coli UMN026 pyridoxamine kinase YP_002412656.1 1949805 R 585056 CDS YP_002412657.1 218705138 7157409 complement(1950727..1952001) 1 NC_011751.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1952001 tyrS 7157409 tyrS Escherichia coli UMN026 tyrosyl-tRNA synthetase YP_002412657.1 1950727 R 585056 CDS YP_002412658.1 218705139 7158151 complement(1952130..1952786) 1 NC_011751.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1952786 pdxH 7158151 pdxH Escherichia coli UMN026 pyridoxamine 5'-phosphate oxidase YP_002412658.1 1952130 R 585056 CDS YP_002412659.1 218705140 7157406 complement(1952845..1953174) 1 NC_011751.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1953174 ydhA 7157406 ydhA Escherichia coli UMN026 lysozyme inhibitor YP_002412659.1 1952845 R 585056 CDS YP_002412660.1 218705141 7158669 complement(1953272..1954381) 1 NC_011751.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1954381 anmK 7158669 anmK Escherichia coli UMN026 anhydro-N-acetylmuramic acid kinase YP_002412660.1 1953272 R 585056 CDS YP_002412661.1 218705142 7155744 1954655..1955122 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein; putative outer membrane lipoprotein 1955122 slyB 7155744 slyB Escherichia coli UMN026 putative outer membrane lipoprotein YP_002412661.1 1954655 D 585056 CDS YP_002412662.1 218705143 7157937 complement(1955169..1955603) 1 NC_011751.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1955603 slyA 7157937 slyA Escherichia coli UMN026 transcriptional regulator SlyA YP_002412662.1 1955169 R 585056 CDS YP_002412663.1 218705144 7157936 1955804..1956040 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1956040 ydhI 7157936 ydhI Escherichia coli UMN026 hypothetical protein YP_002412663.1 1955804 D 585056 CDS YP_002412664.1 218705145 7158674 1956043..1956900 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 1956900 ydhJ 7158674 ydhJ Escherichia coli UMN026 undecaprenyl pyrophosphate phosphatase YP_002412664.1 1956043 D 585056 CDS YP_002412665.1 218705146 7158675 1956900..1958912 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 1958912 ydhK 7158675 ydhK Escherichia coli UMN026 hypothetical protein YP_002412665.1 1956900 D 585056 CDS YP_002412666.1 218705147 7158676 complement(1958913..1959434) 1 NC_011751.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1959434 sodC 7158676 sodC Escherichia coli UMN026 superoxide dismutase YP_002412666.1 1958913 R 585056 CDS YP_002412667.1 218705148 7157947 complement(1959515..1960411) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1960411 ydhF 7157947 ydhF Escherichia coli UMN026 putative oxidoreductase YP_002412667.1 1959515 R 585056 CDS YP_002412668.1 218705149 7158673 1960887..1961402 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1961402 ydhM 7158673 ydhM Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412668.1 1960887 D 585056 CDS YP_002412669.1 218705150 7158677 1961439..1962536 1 NC_011751.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1962536 nemA 7158677 nemA Escherichia coli UMN026 N-ethylmaleimide reductase YP_002412669.1 1961439 D 585056 CDS YP_002412670.1 218705151 7157264 1962617..1963024 1 NC_011751.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1963024 gloA 7157264 gloA Escherichia coli UMN026 glyoxalase I YP_002412670.1 1962617 D 585056 CDS YP_002412671.1 218705152 7156559 1963127..1963774 1 NC_011751.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1963774 rnt 7156559 rnt Escherichia coli UMN026 ribonuclease T YP_002412671.1 1963127 D 585056 CDS YP_002412672.1 218705153 7157719 1963867..1968483 1 NC_011751.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1968483 lhr 7157719 lhr Escherichia coli UMN026 putative ATP-dependent helicase Lhr YP_002412672.1 1963867 D 585056 CDS YP_002412673.1 218705154 7156978 complement(1968534..1968881) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme; hypothetical protein 1968881 ydhD 7156978 ydhD Escherichia coli UMN026 hypothetical protein YP_002412673.1 1968534 R 585056 CDS YP_002412674.1 218705155 7158672 1969216..1970043 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported hydrolase 1970043 ydhO 7158672 ydhO Escherichia coli UMN026 putative exported hydrolase YP_002412674.1 1969216 D 585056 CDS YP_002412675.1 218705156 7158678 1970171..1970752 1 NC_011751.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1970752 sodB 7158678 sodB Escherichia coli UMN026 superoxide dismutase YP_002412675.1 1970171 D 585056 CDS YP_002412676.1 218705157 7157946 complement(1970898..1972067) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative efflux protein; MFS family 1972067 ydhP 7157946 ydhP Escherichia coli UMN026 putative efflux protein; MFS family YP_002412676.1 1970898 R 585056 CDS YP_002412677.1 218705158 7158679 1972621..1973646 1 NC_011751.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1973646 purR 7158679 purR Escherichia coli UMN026 DNA-binding transcriptional repressor PurR YP_002412677.1 1972621 D 585056 CDS YP_002412678.1 218705159 7157583 complement(1973643..1974575) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 1974575 ydhB 7157583 ydhB Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412678.1 1973643 R 585056 CDS YP_002412679.1 218705160 7158670 1974688..1975899 1 NC_011751.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1975899 ydhC 7158670 ydhC Escherichia coli UMN026 inner membrane transport protein YdhC YP_002412679.1 1974688 D 585056 CDS YP_002412680.1 218705161 7158671 1976190..1977338 1 NC_011751.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1977338 cfa 7158671 cfa Escherichia coli UMN026 cyclopropane fatty acyl phospholipid synthase YP_002412680.1 1976190 D 585056 CDS YP_002412681.1 218705162 7155941 complement(1977378..1978019) 1 NC_011751.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1978019 ribC 7155941 ribC Escherichia coli UMN026 riboflavin synthase subunit alpha YP_002412681.1 1977378 R 585056 CDS YP_002412682.1 218705163 7157684 1978234..1979607 1 NC_011751.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1979607 mdtK 7157684 mdtK Escherichia coli UMN026 multidrug efflux protein YP_002412682.1 1978234 D 585056 CDS YP_002412683.1 218705164 7157088 complement(1979648..1980904) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1980904 ydhQ 7157088 ydhQ Escherichia coli UMN026 hypothetical protein YP_002412683.1 1979648 R 585056 CDS YP_002412684.1 218705165 7155572 1981478..1981783 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1981783 ydhR 7155572 ydhR Escherichia coli UMN026 hypothetical protein YP_002412684.1 1981478 D 585056 CDS YP_002412685.1 218705166 7158681 1981909..1983513 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1983513 ydhS 7158681 ydhS Escherichia coli UMN026 hypothetical protein YP_002412685.1 1981909 D 585056 CDS YP_002412686.1 218705167 7158682 complement(1983525..1984337) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1984337 ydhT 7158682 ydhT Escherichia coli UMN026 hypothetical protein YP_002412686.1 1983525 R 585056 CDS YP_002412687.1 218705168 7158683 complement(1984341..1985126) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative cytochrome b subunit of a reductase 1985126 ydhU 7158683 ydhU Escherichia coli UMN026 putative cytochrome b subunit of a reductase YP_002412687.1 1984341 R 585056 CDS YP_002412688.1 218705169 7158684 complement(1985123..1985791) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S ferridoxin-type subunit of oxidoreductase 1985791 ydhX 7158684 ydhX Escherichia coli UMN026 putative 4Fe-4S ferridoxin-type subunit of oxidoreductase YP_002412688.1 1985123 R 585056 CDS YP_002412689.1 218705170 7158687 complement(1985855..1986502) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1986502 ydhW 7158687 ydhW Escherichia coli UMN026 hypothetical protein YP_002412689.1 1985855 R 585056 CDS YP_002412690.1 218705171 7158686 complement(1986506..1988608) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 1988608 ydhV 7158686 ydhV Escherichia coli UMN026 putative oxidoreductase YP_002412690.1 1986506 R 585056 CDS YP_002412691.1 218705172 7158685 complement(1988629..1989255) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; hypothetical protein 1989255 ydhY 7158685 ydhY Escherichia coli UMN026 hypothetical protein YP_002412691.1 1988629 R 585056 CDS YP_002412692.1 218705173 7158688 complement(1989711..1989920) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1989920 ydhZ 7158688 ydhZ Escherichia coli UMN026 hypothetical protein YP_002412692.1 1989711 R 585056 CDS YP_002412693.1 218705174 7158689 1990477..1991889 1 NC_011751.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1991889 pykF 7158689 pykF Escherichia coli UMN026 pyruvate kinase YP_002412693.1 1990477 D 585056 CDS YP_002412694.1 218705175 7157596 1992200..1992436 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein; murein lipoprotein 1992436 lpp 7157596 lpp Escherichia coli UMN026 murein lipoprotein YP_002412694.1 1992200 D 585056 CDS YP_002412695.1 218705176 7157006 complement(1992500..1993504) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1993504 ynhG 7157006 ynhG Escherichia coli UMN026 hypothetical protein YP_002412695.1 1992500 R 585056 CDS YP_002412696.1 218705177 7159531 complement(1993653..1994069) 1 NC_011751.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1994069 sufE 7159531 sufE Escherichia coli UMN026 cysteine desufuration protein SufE YP_002412696.1 1993653 R 585056 CDS YP_002412697.1 218705178 7158006 complement(1994082..1995302) 1 NC_011751.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1995302 sufS 7158006 sufS Escherichia coli UMN026 bifunctional cysteine desulfurase/selenocysteine lyase YP_002412697.1 1994082 R 585056 CDS YP_002412698.1 218705179 7158008 complement(1995299..1996570) 1 NC_011751.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1996570 sufD 7158008 sufD Escherichia coli UMN026 cysteine desulfurase activator complex subunit SufD YP_002412698.1 1995299 R 585056 CDS YP_002412699.1 218705180 7158005 complement(1996545..1997291) 1 NC_011751.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase 1997291 sufC 7158005 sufC Escherichia coli UMN026 cysteine desulfurase ATPase YP_002412699.1 1996545 R 585056 CDS YP_002412700.1 218705181 7158004 complement(1997301..1998788) 1 NC_011751.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1998788 sufB 7158004 sufB Escherichia coli UMN026 cysteine desulfurase activator complex subunit SufB YP_002412700.1 1997301 R 585056 CDS YP_002412701.1 218705182 7158003 complement(1998797..1999165) 1 NC_011751.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1999165 sufA 7158003 sufA Escherichia coli UMN026 iron-sulfur cluster assembly scaffold protein YP_002412701.1 1998797 R 585056 CDS YP_002412702.1 218705183 7157837 complement(1999714..1999983) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1999983 ydiH 7157837 ydiH Escherichia coli UMN026 hypothetical protein YP_002412702.1 1999714 R 585056 CDS YP_002412703.1 218705184 7158695 complement(2000002..2000412) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme; hypothetical protein 2000412 ydiI 7158695 ydiI Escherichia coli UMN026 hypothetical protein YP_002412703.1 2000002 R 585056 CDS YP_002412704.1 218705185 7158696 complement(2000409..2003465) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : putative enzyme; putative FAD-linked oxidoreductase 2003465 ydiJ 7158696 ydiJ Escherichia coli UMN026 putative FAD-linked oxidoreductase YP_002412704.1 2000409 R 585056 CDS YP_002412705.1 218705186 7158697 2003854..2004966 1 NC_011751.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 2004966 ydiK 7158697 ydiK Escherichia coli UMN026 putative inner membrane protein YP_002412705.1 2003854 D 585056 CDS YP_002412706.1 218705187 7157766 2005395..2005751 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2005751 ydiL 7157766 ydiL Escherichia coli UMN026 hypothetical protein YP_002412706.1 2005395 D 585056 CDS YP_002412707.1 218705188 7158699 2005850..2007064 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2007064 ydiM 7158699 ydiM Escherichia coli UMN026 putative MFS superfamily transporter YP_002412707.1 2005850 D 585056 CDS YP_002412708.1 218705189 7158700 2007291..2008556 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 2008556 ydiN 7158700 ydiN Escherichia coli UMN026 putative transporter YP_002412708.1 2007291 D 585056 CDS YP_002412709.1 218705190 7158701 2008568..2009434 1 NC_011751.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 2009434 ydiB 7158701 ydiB Escherichia coli UMN026 quinate/shikimate dehydrogenase YP_002412709.1 2008568 D 585056 CDS YP_002412710.1 218705191 7158691 2009465..2010223 1 NC_011751.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2010223 aroD 7158691 aroD Escherichia coli UMN026 3-dehydroquinate dehydratase YP_002412710.1 2009465 D 585056 CDS YP_002412711.1 218705192 7155786 2010368..2011963 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16253988; Product type e : enzyme; short chain acyl-CoA transferase subunit alpha/beta 2011963 ydiF 7155786 ydiF Escherichia coli UMN026 short chain acyl-CoA transferase subunit alpha/beta YP_002412711.1 2010368 D 585056 CDS YP_002412712.1 218705193 7158694 2011977..2013128 1 NC_011751.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 2013128 ydiO 7158694 ydiO Escherichia coli UMN026 putative acyl-CoA dehydrogenase YP_002412712.1 2011977 D 585056 CDS YP_002412713.1 218705194 7158702 complement(2013171..2014082) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2014082 ydiP 7158702 ydiP Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412713.1 2013171 R 585056 CDS YP_002412714.1 218705195 7158703 complement(2014185..2014361) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2014361 7158703 ECUMN_1986 Escherichia coli UMN026 hypothetical protein YP_002412714.1 2014185 R 585056 CDS YP_002412715.1 218705196 7155054 2014398..2015162 1 NC_011751.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 2015162 ydiQ 7155054 ydiQ Escherichia coli UMN026 putative electron transfer flavoprotein YdiQ YP_002412715.1 2014398 D 585056 CDS YP_002412716.1 218705197 7158704 2015182..2016120 1 NC_011751.1 May play a role in a redox process; electron transfer flavoprotein subunit YdiR 2016120 ydiR 7158704 ydiR Escherichia coli UMN026 electron transfer flavoprotein subunit YdiR YP_002412716.1 2015182 D 585056 CDS YP_002412717.1 218705198 7158705 2016176..2017465 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; hypothetical protein 2017465 ydiS 7158705 ydiS Escherichia coli UMN026 hypothetical protein YP_002412717.1 2016176 D 585056 CDS YP_002412718.1 218705199 7158706 2017462..2017755 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S ferredoxin-type oxidoreductase subunit 2017755 ydiT 7158706 ydiT Escherichia coli UMN026 putative 4Fe-4S ferredoxin-type oxidoreductase subunit YP_002412718.1 2017462 D 585056 CDS YP_002412719.1 218705200 7158707 2017758..2019458 1 NC_011751.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 2019458 ydiD 7158707 ydiD Escherichia coli UMN026 short chain acyl-CoA synthetase YP_002412719.1 2017758 D 585056 CDS YP_002412720.1 218705201 7158692 complement(2019515..2021893) 1 NC_011751.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2021893 pps 7158692 pps Escherichia coli UMN026 phosphoenolpyruvate synthase YP_002412720.1 2019515 R 585056 CDS YP_002412721.1 218705202 7157511 complement(2021947..2022114) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2022114 7157511 ECUMN_1993 Escherichia coli UMN026 hypothetical protein YP_002412721.1 2021947 R 585056 CDS YP_002412722.1 218705203 7155055 2022226..2023059 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2023059 ydiA 7155055 ydiA Escherichia coli UMN026 hypothetical protein YP_002412722.1 2022226 D 585056 CDS YP_002412723.1 218705204 7158690 2023216..2024262 1 NC_011751.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2024262 aroH 7158690 aroH Escherichia coli UMN026 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002412723.1 2023216 D 585056 CDS YP_002412724.1 218705205 7155790 2024394..2024585 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15039350; hypothetical protein 2024585 ydiE 7155790 ydiE Escherichia coli UMN026 hypothetical protein YP_002412724.1 2024394 D 585056 CDS YP_002412725.1 218705206 7158693 complement(2024589..2026025) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2026025 ydiU 7158693 ydiU Escherichia coli UMN026 hypothetical protein YP_002412725.1 2024589 R 585056 CDS YP_002412726.1 218705207 7158708 complement(2026088..2026801) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2026801 ydiV 7158708 ydiV Escherichia coli UMN026 hypothetical protein YP_002412726.1 2026088 R 585056 CDS YP_002412727.1 218705208 7158709 complement(2027048..2027512) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein; putative peptidase lipoprotein 2027512 nlpC 7158709 nlpC Escherichia coli UMN026 putative peptidase lipoprotein YP_002412727.1 2027048 R 585056 CDS YP_002412728.1 218705209 7157287 complement(2027590..2028339) 1 NC_011751.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2028339 btuD 7157287 btuD Escherichia coli UMN026 vitamin B12-transporter ATPase YP_002412728.1 2027590 R 585056 CDS YP_002412729.1 218705210 7155896 complement(2028339..2028890) 1 NC_011751.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase 2028890 btuE 7155896 btuE Escherichia coli UMN026 putative glutathione peroxidase YP_002412729.1 2028339 R 585056 CDS YP_002412730.1 218705211 7155897 complement(2028953..2029933) 1 NC_011751.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2029933 btuC 7155897 btuC Escherichia coli UMN026 vtamin B12-transporter permease YP_002412730.1 2028953 R 585056 CDS YP_002412731.1 218705212 7155895 complement(2030034..2030333) 1 NC_011751.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2030333 ihfA 7155895 ihfA Escherichia coli UMN026 integration host factor subunit alpha YP_002412731.1 2030034 R 585056 CDS YP_002412732.1 218705213 7156794 complement(2030338..2032725) 1 NC_011751.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2032725 pheT 7156794 pheT Escherichia coli UMN026 phenylalanyl-tRNA synthetase subunit beta YP_002412732.1 2030338 R 585056 CDS YP_002412733.1 218705214 7157438 complement(2032740..2033723) 1 NC_011751.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2033723 pheS 7157438 pheS Escherichia coli UMN026 phenylalanyl-tRNA synthetase subunit alpha YP_002412733.1 2032740 R 585056 CDS YP_002412735.1 218705216 7157435 complement(2034029..2034385) 1 NC_011751.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2034385 rplT 7157435 rplT Escherichia coli UMN026 50S ribosomal protein L20 YP_002412735.1 2034029 R 585056 CDS YP_002412736.1 218705217 7157742 complement(2034438..2034635) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure; 50S ribosomal protein L35 2034635 rpmI 7157742 rpmI Escherichia coli UMN026 50S ribosomal protein L35 YP_002412736.1 2034438 R 585056 CDS YP_002412737.1 218705218 7156813 complement(2035278..2037206) 1 NC_011751.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2037206 thrS 7156813 thrS Escherichia coli UMN026 threonyl-tRNA synthetase YP_002412737.1 2035278 R 585056 CDS YP_002412738.1 218705219 7158068 2037729..2039627 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative ankyrin repeat regulatory protein 2039627 7158068 ECUMN_2010 Escherichia coli UMN026 putative ankyrin repeat regulatory protein YP_002412738.1 2037729 D 585056 CDS YP_002412739.1 218705220 7155056 complement(2039954..2040712) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2040712 ydiY 7155056 ydiY Escherichia coli UMN026 hypothetical protein YP_002412739.1 2039954 R 585056 CDS YP_002412740.1 218705221 7158710 2040999..2041928 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme; 6-phosphofructokinase 2 2041928 pfkB 7158710 pfkB Escherichia coli UMN026 6-phosphofructokinase 2 YP_002412740.1 2040999 D 585056 CDS YP_002412741.1 218705222 7157420 2042029..2042319 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2042319 ydiZ 7157420 ydiZ Escherichia coli UMN026 hypothetical protein YP_002412741.1 2042029 D 585056 CDS YP_002412742.1 218705223 7158711 2042425..2043285 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase/kinase 2043285 yniA 7158711 yniA Escherichia coli UMN026 putative phosphotransferase/kinase YP_002412742.1 2042425 D 585056 CDS YP_002412743.1 218705224 7159532 complement(2043326..2043862) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2043862 yniB 7159532 yniB Escherichia coli UMN026 hypothetical protein YP_002412743.1 2043326 R 585056 CDS YP_002412744.1 218705225 7159533 2044009..2044677 1 NC_011751.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2044677 yniC 7159533 yniC Escherichia coli UMN026 2-deoxyglucose-6-phosphatase YP_002412744.1 2044009 D 585056 CDS YP_002412745.1 218705226 7159534 2044840..2045430 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : putative membrane component; hypothetical protein 2045430 ydjM 7159534 ydjM Escherichia coli UMN026 hypothetical protein YP_002412745.1 2044840 D 585056 CDS YP_002412746.1 218705227 7158721 2045563..2046954 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative cation-acid symporter 2046954 ydjN 7158721 ydjN Escherichia coli UMN026 putative cation-acid symporter YP_002412746.1 2045563 D 585056 CDS YP_002412747.1 218705228 7158722 complement(2046958..2047773) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2047773 ydjO 7158722 ydjO Escherichia coli UMN026 hypothetical protein YP_002412747.1 2046958 R 585056 CDS YP_002412748.1 218705229 7158723 complement(2048050..2048313) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process; cell division modulator 2048313 cedA 7158723 cedA Escherichia coli UMN026 cell division modulator YP_002412748.1 2048050 R 585056 CDS YP_002412749.1 218705230 7155940 2048496..2050757 1 NC_011751.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 2050757 katE 7155940 katE Escherichia coli UMN026 hydroperoxidase II YP_002412749.1 2048496 D 585056 CDS YP_002412750.1 218705231 7156881 complement(2050804..2051553) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618; hypothetical protein 2051553 chbG 7156881 chbG Escherichia coli UMN026 hypothetical protein YP_002412750.1 2050804 R 585056 CDS YP_002412751.1 218705232 7155949 complement(2051566..2052918) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme; cryptic phospho-beta-glucosidase 2052918 chbF 7155949 chbF Escherichia coli UMN026 cryptic phospho-beta-glucosidase YP_002412751.1 2051566 R 585056 CDS YP_002412752.1 218705233 7155948 complement(2053023..2053865) 1 NC_011751.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 2053865 chbR 7155948 chbR Escherichia coli UMN026 DNA-binding transcriptional regulator ChbR YP_002412752.1 2053023 R 585056 CDS YP_002412753.1 218705234 7155950 complement(2053873..2054223) 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 2054223 chbA 7155950 chbA Escherichia coli UMN026 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_002412753.1 2053873 R 585056 CDS YP_002412754.1 218705235 7155945 complement(2054274..2055632) 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 2055632 chbC 7155945 chbC Escherichia coli UMN026 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_002412754.1 2054274 R 585056 CDS YP_002412755.1 218705236 7155947 complement(2055717..2056037) 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 2056037 chbB 7155947 chbB Escherichia coli UMN026 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_002412755.1 2055717 R 585056 CDS YP_002412756.1 218705237 7155946 complement(2056336..2056674) 1 NC_011751.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 2056674 osmE 7155946 osmE Escherichia coli UMN026 DNA-binding transcriptional activator OsmE YP_002412756.1 2056336 R 585056 CDS YP_002412757.1 218705238 7157365 2056876..2057703 1 NC_011751.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2057703 nadE 7157365 nadE Escherichia coli UMN026 NAD synthetase YP_002412757.1 2056876 D 585056 CDS YP_002412758.1 218705239 7157225 2057933..2058820 1 NC_011751.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 2058820 ydjQ 7157225 ydjQ Escherichia coli UMN026 nucleotide excision repair endonuclease YP_002412758.1 2057933 D 585056 CDS YP_002412759.1 218705240 7158724 complement(2058780..2059355) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596; hypothetical protein 2059355 ydjR 7158724 ydjR Escherichia coli UMN026 hypothetical protein YP_002412759.1 2058780 R 585056 CDS YP_002412760.1 218705241 7158725 complement(2059558..2060043) 1 NC_011751.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein 2060043 spy 7158725 spy Escherichia coli UMN026 periplasmic protein YP_002412760.1 2059558 R 585056 CDS YP_002412761.1 218705242 7157968 complement(2060373..2061341) 1 NC_011751.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2061341 astE 7157968 astE Escherichia coli UMN026 succinylglutamate desuccinylase YP_002412761.1 2060373 R 585056 CDS YP_002412762.1 218705243 7155826 complement(2061334..2062677) 1 NC_011751.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2062677 astB 7155826 astB Escherichia coli UMN026 succinylarginine dihydrolase YP_002412762.1 2061334 R 585056 CDS YP_002412763.1 218705244 7155823 complement(2062674..2064152) 1 NC_011751.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2064152 astD 7155823 astD Escherichia coli UMN026 succinylglutamic semialdehyde dehydrogenase YP_002412763.1 2062674 R 585056 CDS YP_002412764.1 218705245 7155825 complement(2064149..2065183) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme; arginine succinyltransferase 2065183 astA 7155825 astA Escherichia coli UMN026 arginine succinyltransferase YP_002412764.1 2064149 R 585056 CDS YP_002412765.1 218705246 7155822 complement(2065180..2066400) 1 NC_011751.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2066400 astC 7155822 astC Escherichia coli UMN026 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002412765.1 2065180 R 585056 CDS YP_002412766.1 218705247 7155824 2066846..2067652 1 NC_011751.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2067652 xthA 7155824 xthA Escherichia coli UMN026 exonuclease III YP_002412766.1 2066846 D 585056 CDS YP_002412767.1 218705248 7158251 2067819..2068529 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2068529 ydjX 7158251 ydjX Escherichia coli UMN026 hypothetical protein YP_002412767.1 2067819 D 585056 CDS YP_002412768.1 218705249 7158726 2068534..2069211 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2069211 ydjY 7158726 ydjY Escherichia coli UMN026 hypothetical protein YP_002412768.1 2068534 D 585056 CDS YP_002412769.1 218705250 7158727 2069226..2069933 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2069933 ydjZ 7158727 ydjZ Escherichia coli UMN026 hypothetical protein YP_002412769.1 2069226 D 585056 CDS YP_002412770.1 218705251 7158728 2069933..2070481 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2070481 ynjA 7158728 ynjA Escherichia coli UMN026 hypothetical protein YP_002412770.1 2069933 D 585056 CDS YP_002412771.1 218705252 7159535 2070491..2071657 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative ABC transporter solute-binding protein 2071657 ynjB 7159535 ynjB Escherichia coli UMN026 putative ABC transporter solute-binding protein YP_002412771.1 2070491 D 585056 CDS YP_002412772.1 218705253 7159536 2071675..2073165 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter membrane protein 2073165 ynjC 7159536 ynjC Escherichia coli UMN026 putative ABC transporter membrane protein YP_002412772.1 2071675 D 585056 CDS YP_002412773.1 218705254 7159537 2073078..2073815 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sulfate/thiosulfate ABC transporter ATP-binding protein 2073815 ynjD 7159537 ynjD Escherichia coli UMN026 putative sulfate/thiosulfate ABC transporter ATP-binding protein YP_002412773.1 2073078 D 585056 CDS YP_002412774.1 218705255 7159538 2073885..2075192 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative exported thiosulfate sulfur transferase / thiosulfate binding protein 2075192 ynjE 7159538 ynjE Escherichia coli UMN026 putative exported thiosulfate sulfur transferase / thiosulfate binding protein YP_002412774.1 2073885 D 585056 CDS YP_002412775.1 218705256 7159539 complement(2075201..2075821) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; putative phosphatidyl transferase, inner membrane protein 2075821 ynjF 7159539 ynjF Escherichia coli UMN026 putative phosphatidyl transferase, inner membrane protein YP_002412775.1 2075201 R 585056 CDS YP_002412776.1 218705257 7159540 2075908..2076315 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2076315 nudG 7159540 nudG Escherichia coli UMN026 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_002412776.1 2075908 D 585056 CDS YP_002412777.1 218705258 7157321 2076789..2078132 1 NC_011751.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 2078132 gdhA 7157321 gdhA Escherichia coli UMN026 glutamate dehydrogenase YP_002412777.1 2076789 D 585056 CDS YP_002412778.1 218705259 7156526 complement(2078209..2080221) 1 NC_011751.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2080221 topB 7156526 topB Escherichia coli UMN026 DNA topoisomerase III YP_002412778.1 2078209 R 585056 CDS YP_002412779.1 218705260 7158088 complement(2080169..2081212) 1 NC_011751.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2081212 selD 7158088 selD Escherichia coli UMN026 selenophosphate synthetase YP_002412779.1 2080169 R 585056 CDS YP_002412780.1 218705261 7157895 complement(2081154..2081303) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2081303 7157895 ECUMN_2052 Escherichia coli UMN026 hypothetical protein YP_002412780.1 2081154 R 585056 CDS YP_002412781.1 218705262 7155057 complement(2081329..2081880) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2081880 ydjA 7155057 ydjA Escherichia coli UMN026 hypothetical protein YP_002412781.1 2081329 R 585056 CDS YP_002412782.1 218705263 7158712 2081934..2082098 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2082098 7158712 ECUMN_2054 Escherichia coli UMN026 hypothetical protein YP_002412782.1 2081934 D 585056 CDS YP_002412783.1 218705264 7155058 2082041..2083897 1 NC_011751.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2083897 sppA 7155058 sppA Escherichia coli UMN026 protease 4 YP_002412783.1 2082041 D 585056 CDS YP_002412784.1 218705265 7157965 2084063..2085079 1 NC_011751.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2085079 ansA 7157965 ansA Escherichia coli UMN026 cytoplasmic asparaginase I YP_002412784.1 2084063 D 585056 CDS YP_002412785.1 218705266 7155745 2085090..2085731 1 NC_011751.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2085731 pncA 7155745 pncA Escherichia coli UMN026 nicotinamidase/pyrazinamidase YP_002412785.1 2085090 D 585056 CDS YP_002412786.1 218705267 7157478 complement(2085824..2087182) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2087182 ydjE 7157478 ydjE Escherichia coli UMN026 putative MFS superfamily transporter YP_002412786.1 2085824 R 585056 CDS YP_002412787.1 218705268 7158713 complement(2087300..2088058) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2088058 ydjF 7158713 ydjF Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412787.1 2087300 R 585056 CDS YP_002412788.1 218705269 7158714 complement(2088195..2089175) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2089175 ydjG 7158714 ydjG Escherichia coli UMN026 putative oxidoreductase YP_002412788.1 2088195 R 585056 CDS YP_002412789.1 218705270 7158715 complement(2089185..2090132) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar kinase 2090132 ydjH 7158715 ydjH Escherichia coli UMN026 putative sugar kinase YP_002412789.1 2089185 R 585056 CDS YP_002412790.1 218705271 7158716 complement(2090137..2090973) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldolase 2090973 ydjI 7158716 ydjI Escherichia coli UMN026 putative aldolase YP_002412790.1 2090137 R 585056 CDS YP_002412791.1 218705272 7158717 complement(2090994..2092037) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12897001; Product type pe : putative enzyme; putative iditol dehydrogenase 2092037 ydjJ 7158717 ydjJ Escherichia coli UMN026 putative iditol dehydrogenase YP_002412791.1 2090994 R 585056 CDS YP_002412792.1 218705273 7158718 complement(2092054..2093433) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2093433 ydjK 7158718 ydjK Escherichia coli UMN026 putative MFS superfamily transporter YP_002412792.1 2092054 R 585056 CDS YP_002412793.1 218705274 7158719 complement(2093460..2094536) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2094536 ydjL 7158719 ydjL Escherichia coli UMN026 putative oxidoreductase YP_002412793.1 2093460 R 585056 CDS YP_002412794.1 218705275 7158720 complement(2094906..2095178) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2095178 yeaC 7158720 yeaC Escherichia coli UMN026 hypothetical protein YP_002412794.1 2094906 R 585056 CDS YP_002412795.1 218705276 7158730 complement(2095220..2095633) 1 NC_011751.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2095633 msrB 7158730 msrB Escherichia coli UMN026 methionine sulfoxide reductase B YP_002412795.1 2095220 R 585056 CDS YP_002412796.1 218705277 7157188 2095975..2096970 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase A 2096970 gapA 7157188 gapA Escherichia coli UMN026 glyceraldehyde-3-phosphate dehydrogenase A YP_002412796.1 2095975 D 585056 CDS YP_002412797.1 218705278 7156503 2097054..2097938 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2097938 yeaD 7156503 yeaD Escherichia coli UMN026 hypothetical protein YP_002412797.1 2097054 D 585056 CDS YP_002412798.1 218705279 7158731 complement(2097989..2098843) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2098843 yeaE 7158731 yeaE Escherichia coli UMN026 putative oxidoreductase YP_002412798.1 2097989 R 585056 CDS YP_002412799.1 218705280 7158732 complement(2098933..2099679) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor; scaffolding protein for murein synthesizing machinery 2099679 mipA 7158732 mipA Escherichia coli UMN026 scaffolding protein for murein synthesizing machinery YP_002412799.1 2098933 R 585056 CDS YP_002412800.1 218705281 7157137 2100115..2102049 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2102049 yeaG 7157137 yeaG Escherichia coli UMN026 hypothetical protein YP_002412800.1 2100115 D 585056 CDS YP_002412801.1 218705282 7158733 2102162..2103445 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2103445 yeaH 7158733 yeaH Escherichia coli UMN026 hypothetical protein YP_002412801.1 2102162 D 585056 CDS YP_002412802.1 218705283 7158734 2103592..2105067 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2105067 yeaI 7158734 yeaI Escherichia coli UMN026 putative diguanylate cyclase YP_002412802.1 2103592 D 585056 CDS YP_002412803.1 218705284 7158735 2105248..2106738 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2106738 yeaJ 7158735 yeaJ Escherichia coli UMN026 putative diguanylate cyclase YP_002412803.1 2105248 D 585056 CDS YP_002412804.1 218705285 7158736 2106781..2107284 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2107284 yeaK 7158736 yeaK Escherichia coli UMN026 hypothetical protein YP_002412804.1 2106781 D 585056 CDS YP_002412805.1 218705286 7158737 complement(2107285..2107437) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2107437 7158737 ECUMN_2077 Escherichia coli UMN026 hypothetical protein YP_002412805.1 2107285 R 585056 CDS YP_002412806.1 218705287 7155059 2107559..2108005 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2108005 yeaL 7155059 yeaL Escherichia coli UMN026 hypothetical protein YP_002412806.1 2107559 D 585056 CDS YP_002412807.1 218705288 7158738 complement(2107962..2108783) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2108783 yeaM 7158738 yeaM Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412807.1 2107962 R 585056 CDS YP_002412808.1 218705289 7158739 2108880..2110061 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2110061 yeaN 7158739 yeaN Escherichia coli UMN026 putative MFS superfamily transporter YP_002412808.1 2108880 D 585056 CDS YP_002412809.1 218705290 7158740 2110116..2110463 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2110463 yeaO 7158740 yeaO Escherichia coli UMN026 hypothetical protein YP_002412809.1 2110116 D 585056 CDS YP_002412810.1 218705291 7158741 complement(2110485..2110739) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2110739 yoaF 7158741 yoaF Escherichia coli UMN026 hypothetical protein YP_002412810.1 2110485 R 585056 CDS YP_002412811.1 218705292 7159545 2110922..2111947 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2111947 yeaP 7159545 yeaP Escherichia coli UMN026 putative diguanylate cyclase YP_002412811.1 2110922 D 585056 CDS YP_002412812.1 218705293 7158742 complement(2112214..2112462) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2112462 yeaQ 7158742 yeaQ Escherichia coli UMN026 hypothetical protein YP_002412812.1 2112214 R 585056 CDS YP_002412813.1 218705294 7158743 complement(2112610..2112792) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2112792 yoaG 7158743 yoaG Escherichia coli UMN026 hypothetical protein YP_002412813.1 2112610 R 585056 CDS YP_002412814.1 218705295 7159546 complement(2112796..2113155) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2113155 yeaR 7159546 yeaR Escherichia coli UMN026 hypothetical protein YP_002412814.1 2112796 R 585056 CDS YP_002412815.1 218705296 7158744 complement(2113328..2113966) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; leucine export protein LeuE 2113966 yeaS 7158744 yeaS Escherichia coli UMN026 leucine export protein LeuE YP_002412815.1 2113328 R 585056 CDS YP_002412816.1 218705297 7158745 complement(2114093..2115016) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2115016 yeaT 7158745 yeaT Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002412816.1 2114093 R 585056 CDS YP_002412817.1 218705298 7158746 2115119..2116204 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative tartrate dehydrogenase 2116204 yeaU 7158746 yeaU Escherichia coli UMN026 putative tartrate dehydrogenase YP_002412817.1 2115119 D 585056 CDS YP_002412818.1 218705299 7158747 2116455..2116769 1 NC_011751.1 Evidence 7 : Gene remnant; Product type pt : putative transporter; putative quarternary ammonium transport protein (fragment) 2116769 7158747 ECUMN_2092 Escherichia coli UMN026 putative quarternary ammonium transport protein (fragment) YP_002412818.1 2116455 D 585056 CDS YP_002412819.1 218705300 7158748 2118097..2119221 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 2Fe-2S cluster-containing dioxygenase subunit 2119221 yeaW 7158748 yeaW Escherichia coli UMN026 putative 2Fe-2S cluster-containing dioxygenase subunit YP_002412819.1 2118097 D 585056 CDS YP_002412820.1 218705301 7158749 2119277..2120242 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dioxygenase subunit 2120242 yeaX 7158749 yeaX Escherichia coli UMN026 putative dioxygenase subunit YP_002412820.1 2119277 D 585056 CDS YP_002412821.1 218705302 7158750 complement(2120296..2121423) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme; ribonuclease D 2121423 rnd 7158750 rnd Escherichia coli UMN026 ribonuclease D YP_002412821.1 2120296 R 585056 CDS YP_002412822.1 218705303 7157710 complement(2121493..2123178) 1 NC_011751.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2123178 fadD 7157710 fadD Escherichia coli UMN026 long-chain-fatty-acid--CoA ligase YP_002412822.1 2121493 R 585056 CDS YP_002412823.1 218705304 7156304 complement(2123383..2123964) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein; putative outer membrane-associated lipoprotein 2123964 yeaY 7156304 yeaY Escherichia coli UMN026 putative outer membrane-associated lipoprotein YP_002412823.1 2123383 R 585056 CDS YP_002412824.1 218705305 7158751 complement(2124003..2124698) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2124698 yeaZ 7158751 yeaZ Escherichia coli UMN026 putative peptidase YP_002412824.1 2124003 R 585056 CDS YP_002412825.1 218705306 7158752 complement(2124756..2126666) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATP-dependent helicase 2126666 yoaA 7158752 yoaA Escherichia coli UMN026 putative ATP-dependent helicase YP_002412825.1 2124756 R 585056 CDS YP_002412826.1 218705307 7159541 2126798..2127142 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2127142 yoaB 7159541 yoaB Escherichia coli UMN026 hypothetical protein YP_002412826.1 2126798 D 585056 CDS YP_002412827.1 218705308 7159542 2127504..2127863 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2127863 yoaC 7159542 yoaC Escherichia coli UMN026 hypothetical protein YP_002412827.1 2127504 D 585056 CDS YP_002412828.1 218705309 7159543 complement(2127983..2128162) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2128162 yoaH 7159543 yoaH Escherichia coli UMN026 hypothetical protein YP_002412828.1 2127983 R 585056 CDS YP_002412829.1 218705310 7159547 2128236..2129597 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme; aminodeoxychorismate synthase, subunit I 2129597 pabB 7159547 pabB Escherichia coli UMN026 aminodeoxychorismate synthase, subunit I YP_002412829.1 2128236 D 585056 CDS YP_002412830.1 218705311 7157374 2129601..2130179 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme; hypothetical protein 2130179 yeaB 7157374 yeaB Escherichia coli UMN026 hypothetical protein YP_002412830.1 2129601 D 585056 CDS YP_002412831.1 218705312 7158729 2130363..2131727 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme; L-serine deaminase I 2131727 sdaA 7158729 sdaA Escherichia coli UMN026 L-serine deaminase I YP_002412831.1 2130363 D 585056 CDS YP_002412832.1 218705313 7157877 2131858..2133456 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : putative enzyme; putative cyclic di-GMP phosphodiesterase 2133456 adrB 7157877 adrB Escherichia coli UMN026 putative cyclic di-GMP phosphodiesterase YP_002412832.1 2131858 D 585056 CDS YP_002412833.1 218705314 7155704 complement(2133460..2135016) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 2135016 yoaE 7155704 yoaE Escherichia coli UMN026 hypothetical protein YP_002412833.1 2133460 R 585056 CDS YP_002412834.1 218705315 7159544 2135479..2136450 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter; PTS system mannose-specific transporter subunit IIAB 2136450 manX 7159544 manX Escherichia coli UMN026 PTS system mannose-specific transporter subunit IIAB YP_002412834.1 2135479 D 585056 CDS YP_002412835.1 218705316 7157056 2136513..2137313 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter; mannose-specific enzyme IIC component of PTS 2137313 manY 7157056 manY Escherichia coli UMN026 mannose-specific enzyme IIC component of PTS YP_002412835.1 2136513 D 585056 CDS YP_002412836.1 218705317 7157057 2137317..2138177 1 NC_011751.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2138177 manZ 7157057 manZ Escherichia coli UMN026 PTS system mannose-specific transporter subunit IID YP_002412836.1 2137317 D 585056 CDS YP_002412837.1 218705318 7157058 2138232..2138690 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2138690 yobD 7157058 yobD Escherichia coli UMN026 hypothetical protein YP_002412837.1 2138232 D 585056 CDS YP_002412838.1 218705319 7159550 2138877..2139122 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2139122 7159550 ECUMN_2113 Escherichia coli UMN026 hypothetical protein YP_002412838.1 2138877 D 585056 CDS YP_002412839.1 218705320 7155061 2139119..2139685 1 NC_011751.1 membrane protein YebN; hypothetical protein 2139685 yebN 7155061 yebN Escherichia coli UMN026 hypothetical protein YP_002412839.1 2139119 D 585056 CDS YP_002412840.1 218705321 7158760 complement(2139682..2140491) 1 NC_011751.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2140491 rrmA 7158760 rrmA Escherichia coli UMN026 23S rRNA methyltransferase A YP_002412840.1 2139682 R 585056 CDS YP_002412841.1 218705322 7157789 complement(2140657..2140866) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor; cold shock-like protein CspC 2140866 cspC 7157789 cspC Escherichia coli UMN026 cold shock-like protein CspC YP_002412841.1 2140657 R 585056 CDS YP_002412842.1 218705323 7156036 complement(2140879..2141022) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2141022 yobF 7156036 yobF Escherichia coli UMN026 hypothetical protein YP_002412842.1 2140879 R 585056 CDS YP_002412843.1 218705324 7159551 complement(2141692..2141979) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2141979 yebO 7159551 yebO Escherichia coli UMN026 hypothetical protein YP_002412843.1 2141692 R 585056 CDS YP_002412844.1 218705325 7158761 complement(2142054..2142197) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2142197 yobG 7158761 yobG Escherichia coli UMN026 hypothetical protein YP_002412844.1 2142054 R 585056 CDS YP_002412845.1 218705326 7159553 complement(2142738..2143529) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator; DNA-binding transcriptional repressor KdgR 2143529 kdgR 7159553 kdgR Escherichia coli UMN026 DNA-binding transcriptional repressor KdgR YP_002412845.1 2142738 R 585056 CDS YP_002412846.1 218705327 7156888 2143706..2145079 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative MFS superfamily transporter 2145079 yebQ 7156888 yebQ Escherichia coli UMN026 putative MFS superfamily transporter YP_002412846.1 2143706 D 585056 CDS YP_002412847.1 218705328 7158762 complement(2145125..2146006) 1 NC_011751.1 putative metalloprotease; heat shock protein HtpX 2146006 htpX 7158762 htpX Escherichia coli UMN026 heat shock protein HtpX YP_002412847.1 2145125 R 585056 CDS YP_002412848.1 218705329 7156727 complement(2146198..2148246) 1 NC_011751.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 2148246 prc 7156727 prc Escherichia coli UMN026 carboxy-terminal protease YP_002412848.1 2146198 R 585056 CDS YP_002412849.1 218705330 7157516 complement(2148266..2148964) 1 NC_011751.1 affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector 2148964 proQ 7157516 proQ Escherichia coli UMN026 putative solute/DNA competence effector YP_002412849.1 2148266 R 585056 CDS YP_002412850.1 218705331 7157534 complement(2149061..2149612) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2149612 yebR 7157534 yebR Escherichia coli UMN026 hypothetical protein YP_002412850.1 2149061 R 585056 CDS YP_002412851.1 218705332 7158763 2149688..2150971 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2150971 yebS 7158763 yebS Escherichia coli UMN026 hypothetical protein YP_002412851.1 2149688 D 585056 CDS YP_002412852.1 218705333 7158764 2150940..2153573 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2153573 yebT 7158764 yebT Escherichia coli UMN026 hypothetical protein YP_002412852.1 2150940 D 585056 CDS YP_002412853.1 218705334 7158765 2153653..2155092 1 NC_011751.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2155092 yebU 7158765 yebU Escherichia coli UMN026 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_002412853.1 2153653 D 585056 CDS YP_002412854.1 218705335 7158766 2155210..2155446 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2155446 yebV 7158766 yebV Escherichia coli UMN026 hypothetical protein YP_002412854.1 2155210 D 585056 CDS YP_002412855.1 218705336 7158767 2155467..2155742 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2155742 yebW 7158767 yebW Escherichia coli UMN026 hypothetical protein YP_002412855.1 2155467 D 585056 CDS YP_002412856.1 218705337 7158768 complement(2155743..2156399) 1 NC_011751.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 2156399 pphA 7158768 pphA Escherichia coli UMN026 serine/threonine protein phosphatase 1 YP_002412856.1 2155743 R 585056 CDS YP_002412857.1 218705338 7155062 complement(2156795..2157136) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2157136 yebY 7155062 yebY Escherichia coli UMN026 hypothetical protein YP_002412857.1 2156795 R 585056 CDS YP_002412858.1 218705339 7158769 complement(2157149..2158021) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2158021 yebZ 7158769 yebZ Escherichia coli UMN026 hypothetical protein YP_002412858.1 2157149 R 585056 CDS YP_002412859.1 218705340 7158770 complement(2158025..2158399) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2158399 yobA 7158770 yobA Escherichia coli UMN026 hypothetical protein YP_002412859.1 2158025 R 585056 CDS YP_002412860.1 218705341 7159548 2158538..2158768 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15090519, 92147649, 92156151, 94131961, 1575709, 8341603, 8505306; Product type e : enzyme; DNA polymerase III subunit theta 2158768 holE 7159548 holE Escherichia coli UMN026 DNA polymerase III subunit theta YP_002412860.1 2158538 D 585056 CDS YP_002412861.1 218705342 7156700 2158870..2159526 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2159526 yobB 7156700 yobB Escherichia coli UMN026 hypothetical protein YP_002412861.1 2158870 D 585056 CDS YP_002412862.1 218705343 7159549 2159550..2160212 1 NC_011751.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2160212 exoX 7159549 exoX Escherichia coli UMN026 exodeoxyribonuclease X YP_002412862.1 2159550 D 585056 CDS YP_002412863.1 218705344 7156290 complement(2160209..2162269) 1 NC_011751.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 2162269 ptrB 7156290 ptrB Escherichia coli UMN026 protease 2 YP_002412863.1 2160209 R 585056 CDS YP_002412864.1 218705345 7157564 complement(2162426..2162851) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS200, part of IS605 with following ORF 2162851 7157564 ECUMN_2141 Escherichia coli UMN026 transposase, IS200, part of IS605 with following ORF YP_002412864.1 2162426 R 585056 CDS YP_002412865.1 218705346 7155063 2162908..2164077 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, part of IS605 with preceding ORF 2164077 7155063 ECUMN_2142 Escherichia coli UMN026 transposase, part of IS605 with preceding ORF YP_002412865.1 2162908 D 585056 CDS YP_002412866.1 218705347 7155064 complement(2164241..2164900) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2164900 yebE 7155064 yebE Escherichia coli UMN026 hypothetical protein YP_002412866.1 2164241 R 585056 CDS YP_002412867.1 218705348 7158756 complement(2165227..2165595) 1 NC_011751.1 secreted protein; unknown function; hypothetical protein 2165595 yebF 7158756 yebF Escherichia coli UMN026 hypothetical protein YP_002412867.1 2165227 R 585056 CDS YP_002412868.1 218705349 7158757 complement(2165650..2165940) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9368369, 99403401; Product type cp : cell process; DNA damage-inducible protein YebG 2165940 yebG 7158757 yebG Escherichia coli UMN026 DNA damage-inducible protein YebG YP_002412868.1 2165650 R 585056 CDS YP_002412869.1 218705350 7158758 2166074..2167252 1 NC_011751.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2167252 purT 7158758 purT Escherichia coli UMN026 phosphoribosylglycinamide formyltransferase 2 YP_002412869.1 2166074 D 585056 CDS YP_002412870.1 218705351 7157584 complement(2167307..2167948) 1 NC_011751.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2167948 eda 7157584 eda Escherichia coli UMN026 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002412870.1 2167307 R 585056 CDS YP_002412871.1 218705352 7156226 complement(2167985..2169796) 1 NC_011751.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2169796 edd 7156226 edd Escherichia coli UMN026 phosphogluconate dehydratase YP_002412871.1 2167985 R 585056 CDS YP_002412872.1 218705353 7156227 complement(2170031..2171506) 1 NC_011751.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2171506 zwf 7156227 zwf Escherichia coli UMN026 glucose-6-phosphate 1-dehydrogenase YP_002412872.1 2170031 R 585056 CDS YP_002412873.1 218705354 7159697 2171844..2172713 1 NC_011751.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2172713 yebK 7159697 yebK Escherichia coli UMN026 DNA-binding transcriptional regulator HexR YP_002412873.1 2171844 D 585056 CDS YP_002412874.1 218705355 7158759 2172841..2174283 1 NC_011751.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2174283 pykA 7158759 pykA Escherichia coli UMN026 pyruvate kinase YP_002412874.1 2172841 D 585056 CDS YP_002412875.1 218705356 7157595 complement(2174415..2175386) 1 NC_011751.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2175386 lpxM 7157595 lpxM Escherichia coli UMN026 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002412875.1 2174415 R 585056 CDS YP_002412876.1 218705357 7157016 complement(2175506..2176828) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : putative enzyme; hypothetical protein 2176828 yebA 7157016 yebA Escherichia coli UMN026 hypothetical protein YP_002412876.1 2175506 R 585056 CDS YP_002412877.1 218705358 7158753 complement(2176844..2177776) 1 NC_011751.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component 2177776 znuA 7158753 znuA Escherichia coli UMN026 high-affinity zinc transporter periplasmic component YP_002412877.1 2176844 R 585056 CDS YP_002412878.1 218705359 7159689 2177855..2178610 1 NC_011751.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2178610 znuC 7159689 znuC Escherichia coli UMN026 high-affinity zinc transporter ATPase YP_002412878.1 2177855 D 585056 CDS YP_002412879.1 218705360 7159691 2178607..2179392 1 NC_011751.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2179392 znuB 7159691 znuB Escherichia coli UMN026 high-affinity zinc transporter membrane component YP_002412879.1 2178607 D 585056 CDS YP_002412880.1 218705361 7159690 complement(2179544..2180554) 1 NC_011751.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2180554 ruvB 7159690 ruvB Escherichia coli UMN026 Holliday junction DNA helicase RuvB YP_002412880.1 2179544 R 585056 CDS YP_002412881.1 218705362 7157831 complement(2180563..2181174) 1 NC_011751.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2181174 ruvA 7157831 ruvA Escherichia coli UMN026 Holliday junction DNA helicase RuvA YP_002412881.1 2180563 R 585056 CDS YP_002412882.1 218705363 7157830 2181449..2182051 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2182051 yebB 7157830 yebB Escherichia coli UMN026 hypothetical protein YP_002412882.1 2181449 D 585056 CDS YP_002412883.1 218705364 7158754 complement(2182053..2182574) 1 NC_011751.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2182574 ruvC 7158754 ruvC Escherichia coli UMN026 Holliday junction resolvase YP_002412883.1 2182053 R 585056 CDS YP_002412884.1 218705365 7157832 complement(2182609..2183349) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2183349 yebC 7157832 yebC Escherichia coli UMN026 hypothetical protein YP_002412884.1 2182609 R 585056 CDS YP_002412885.1 218705366 7158755 complement(2183378..2183821) 1 NC_011751.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2183821 ntpA 7158755 ntpA Escherichia coli UMN026 dATP pyrophosphohydrolase YP_002412885.1 2183378 R 585056 CDS YP_002412886.1 218705367 7157316 complement(2183823..2185595) 1 NC_011751.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2185595 aspS 7157316 aspS Escherichia coli UMN026 aspartyl-tRNA synthetase YP_002412886.1 2183823 R 585056 CDS YP_002412887.1 218705368 7155819 2185905..2186471 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2186471 yecD 7155819 yecD Escherichia coli UMN026 hypothetical protein YP_002412887.1 2185905 D 585056 CDS YP_002412888.1 218705369 7158773 2186468..2187286 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428; hypothetical protein 2187286 yecE 7158773 yecE Escherichia coli UMN026 hypothetical protein YP_002412888.1 2186468 D 585056 CDS YP_002412889.1 218705370 7158774 2187339..2187734 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2187734 yecN 7158774 yecN Escherichia coli UMN026 hypothetical protein YP_002412889.1 2187339 D 585056 CDS YP_002412890.1 218705371 7158781 2187775..2188518 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme; AdoMet-dependent methyltransferase 2188518 yecO 7158781 yecO Escherichia coli UMN026 AdoMet-dependent methyltransferase YP_002412890.1 2187775 D 585056 CDS YP_002412891.1 218705372 7158782 2188515..2189486 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2189486 yecP 7158782 yecP Escherichia coli UMN026 hypothetical protein YP_002412891.1 2188515 D 585056 CDS YP_002412892.1 218705373 7158783 complement(2189521..2191950) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97077292, 11004177; Product type e : enzyme; trimethylamine N-oxide reductase system III, catalytic subunit 2191950 torZ 7158783 torZ Escherichia coli UMN026 trimethylamine N-oxide reductase system III, catalytic subunit YP_002412892.1 2189521 R 585056 CDS YP_002412893.1 218705374 7158096 complement(2191975..2193075) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461225, 8919859; Product type c : carrier; TMAO reductase III (TorYZ), cytochrome c-type subunit 2193075 torY 7158096 torY Escherichia coli UMN026 TMAO reductase III (TorYZ), cytochrome c-type subunit YP_002412893.1 2191975 R 585056 CDS YP_002412894.1 218705375 7158095 complement(2193461..2194207) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter; copper homeostasis protein CutC 2194207 cutC 7158095 cutC Escherichia coli UMN026 copper homeostasis protein CutC YP_002412894.1 2193461 R 585056 CDS YP_002412895.1 218705376 7156057 complement(2194221..2194787) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : putative enzyme; hypothetical protein 2194787 yecM 7156057 yecM Escherichia coli UMN026 hypothetical protein YP_002412895.1 2194221 R 585056 CDS YP_002412896.1 218705377 7158780 2195003..2196736 1 NC_011751.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2196736 argS 7158780 argS Escherichia coli UMN026 arginyl-tRNA synthetase YP_002412896.1 2195003 D 585056 CDS YP_002412897.1 218705378 7155780 complement(2196789..2197181) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349; hypothetical protein 2197181 flhE 7155780 flhE Escherichia coli UMN026 hypothetical protein YP_002412897.1 2196789 R 585056 CDS YP_002412898.1 218705379 7156395 complement(2197181..2199259) 1 NC_011751.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2199259 flhA 7156395 flhA Escherichia coli UMN026 flagellar biosynthesis protein FlhA YP_002412898.1 2197181 R 585056 CDS YP_002412899.1 218705380 7156391 complement(2199252..2200400) 1 NC_011751.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 2200400 flhB 7156391 flhB Escherichia coli UMN026 flagellar biosynthesis protein FlhB YP_002412899.1 2199252 R 585056 CDS YP_002412900.1 218705381 7156392 complement(2200602..2201246) 1 NC_011751.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 2201246 cheZ 7156392 cheZ Escherichia coli UMN026 chemotaxis regulator CheZ YP_002412900.1 2200602 R 585056 CDS YP_002412901.1 218705382 7155956 complement(2201257..2201646) 1 NC_011751.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 2201646 cheY 7155956 cheY Escherichia coli UMN026 chemotaxis regulatory protein CheY YP_002412901.1 2201257 R 585056 CDS YP_002412902.1 218705383 7155955 complement(2201661..2202710) 1 NC_011751.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 2202710 cheB 7155955 cheB Escherichia coli UMN026 chemotaxis-specific methylesterase YP_002412902.1 2201661 R 585056 CDS YP_002412903.1 218705384 7155952 complement(2202713..2203573) 1 NC_011751.1 methylates the MCP; chemotaxis methyltransferase CheR 2203573 cheR 7155952 cheR Escherichia coli UMN026 chemotaxis methyltransferase CheR YP_002412903.1 2202713 R 585056 CDS YP_002412904.1 218705385 7155953 complement(2203592..2205193) 1 NC_011751.1 mediates taxis toward dipeptides; methyl-accepting protein IV 2205193 tap 7155953 tap Escherichia coli UMN026 methyl-accepting protein IV YP_002412904.1 2203592 R 585056 CDS YP_002412905.1 218705386 7158022 complement(2205239..2206900) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator; methyl-accepting chemotaxis protein II 2206900 tar 7158022 tar Escherichia coli UMN026 methyl-accepting chemotaxis protein II YP_002412905.1 2205239 R 585056 CDS YP_002412906.1 218705387 7155905 complement(2207045..2207548) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator; purine-binding chemotaxis protein 2207548 cheW 7155905 cheW Escherichia coli UMN026 purine-binding chemotaxis protein YP_002412906.1 2207045 R 585056 CDS YP_002412907.1 218705388 7155954 complement(2207569..2209533) 1 NC_011751.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 2209533 cheA 7155954 cheA Escherichia coli UMN026 chemotaxis protein CheA YP_002412907.1 2207569 R 585056 CDS YP_002412908.1 218705389 7155951 complement(2209538..2210464) 1 NC_011751.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 2210464 motB 7155951 motB Escherichia coli UMN026 flagellar motor protein MotB YP_002412908.1 2209538 R 585056 CDS YP_002412909.1 218705390 7157163 complement(2210461..2211348) 1 NC_011751.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 2211348 motA 7157163 motA Escherichia coli UMN026 flagellar motor protein MotA YP_002412909.1 2210461 R 585056 CDS YP_002412910.1 218705391 7157162 complement(2211475..2212053) 1 NC_011751.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 2212053 flhC 7157162 flhC Escherichia coli UMN026 transcriptional activator FlhC YP_002412910.1 2211475 R 585056 CDS YP_002412911.1 218705392 7156393 complement(2212056..2212415) 1 NC_011751.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 2212415 flhD 7156393 flhD Escherichia coli UMN026 transcriptional activator FlhD YP_002412911.1 2212056 R 585056 CDS YP_002412912.1 218705393 7156394 2213187..2213615 1 NC_011751.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2213615 yecG 7156394 yecG Escherichia coli UMN026 universal stress protein UspC YP_002412912.1 2213187 D 585056 CDS YP_002412913.1 218705394 7158776 complement(2213622..2215046) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme; trehalose-6-phosphate synthase 2215046 otsA 7158776 otsA Escherichia coli UMN026 trehalose-6-phosphate synthase YP_002412913.1 2213622 R 585056 CDS YP_002412914.1 218705395 7157367 complement(2215021..2215821) 1 NC_011751.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 2215821 otsB 7157367 otsB Escherichia coli UMN026 trehalose-6-phosphate phosphatase YP_002412914.1 2215021 R 585056 CDS YP_002412915.1 218705396 7157368 complement(2215988..2216977) 1 NC_011751.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease protein 2216977 araH 7157368 araH Escherichia coli UMN026 L-arabinose transporter permease protein YP_002412915.1 2215988 R 585056 CDS YP_002412916.1 218705397 7155764 complement(2216989..2218503) 1 NC_011751.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2218503 araG 7155764 araG Escherichia coli UMN026 L-arabinose transporter ATP-binding protein YP_002412916.1 2216989 R 585056 CDS YP_002412917.1 218705398 7155763 complement(2218573..2219562) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter; L-arabinose ABC transporter periplasmic-binding protein 2219562 araF 7155763 araF Escherichia coli UMN026 L-arabinose ABC transporter periplasmic-binding protein YP_002412917.1 2218573 R 585056 CDS YP_002412918.1 218705399 7155762 2220359..2220862 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative ferritin-like protein 2220862 yecI 7155762 yecI Escherichia coli UMN026 putative ferritin-like protein YP_002412918.1 2220359 D 585056 CDS YP_002412919.1 218705400 7158778 complement(2220942..2221193) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2221193 yecJ 7158778 yecJ Escherichia coli UMN026 hypothetical protein YP_002412919.1 2220942 R 585056 CDS YP_002412920.1 218705401 7156871 2221305..2221451 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2221451 7156871 ECUMN_2198 Escherichia coli UMN026 hypothetical protein YP_002412920.1 2221305 D 585056 CDS YP_002412921.1 218705402 7155065 2221657..2221980 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2221980 yecR 7155065 yecR Escherichia coli UMN026 hypothetical protein YP_002412921.1 2221657 D 585056 CDS YP_002412922.1 218705403 7158784 2222151..2222648 1 NC_011751.1 cytoplasmic iron storage protein; ferritin 2222648 ftn 7158784 ftn Escherichia coli UMN026 ferritin YP_002412922.1 2222151 D 585056 CDS YP_002412923.1 218705404 7156455 complement(2222686..2222925) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2222925 yecH 7156455 yecH Escherichia coli UMN026 hypothetical protein YP_002412923.1 2222686 R 585056 CDS YP_002412924.1 218705405 7158777 2223116..2224327 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter; tyrosine transporter 2224327 tyrP 7158777 tyrP Escherichia coli UMN026 tyrosine transporter YP_002412924.1 2223116 D 585056 CDS YP_002412925.1 218705406 7158149 complement(2224389..2225054) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2225054 yecA 7158149 yecA Escherichia coli UMN026 hypothetical protein YP_002412925.1 2224389 R 585056 CDS YP_002412926.1 218705407 7155636 complement(2225704..2226252) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme; phosphatidylglycerophosphate synthetase 2226252 pgsA 7155636 pgsA Escherichia coli UMN026 phosphatidylglycerophosphate synthetase YP_002412926.1 2225704 R 585056 CDS YP_002412927.1 218705408 7157432 complement(2226309..2228141) 1 NC_011751.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2228141 uvrC 7157432 uvrC Escherichia coli UMN026 excinuclease ABC subunit C YP_002412927.1 2226309 R 585056 CDS YP_002412928.1 218705409 7158200 complement(2228138..2228794) 1 NC_011751.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2228794 uvrY 7158200 uvrY Escherichia coli UMN026 response regulator YP_002412928.1 2228138 R 585056 CDS YP_002412929.1 218705410 7158202 2229253..2229477 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469; hypothetical protein 2229477 yecF 7158202 yecF Escherichia coli UMN026 hypothetical protein YP_002412929.1 2229253 D 585056 CDS YP_002412930.1 218705411 7158775 complement(2229545..2230267) 1 NC_011751.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 2230267 sdiA 7158775 sdiA Escherichia coli UMN026 DNA-binding transcriptional activator SdiA YP_002412930.1 2229545 R 585056 CDS YP_002412931.1 218705412 7157884 complement(2230497..2231249) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino-acid ABC transporter ATP-binding protein YecC 2231249 yecC 7157884 yecC Escherichia coli UMN026 putative amino-acid ABC transporter ATP-binding protein YecC YP_002412931.1 2230497 R 585056 CDS YP_002412932.1 218705413 7158772 complement(2231246..2231914) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease 2231914 yecS 7158772 yecS Escherichia coli UMN026 putative ABC transporter permease YP_002412932.1 2231246 R 585056 CDS YP_002412933.1 218705414 7158785 complement(2231929..2232915) 1 NC_011751.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2232915 yedO 7158785 yedO Escherichia coli UMN026 D-cysteine desulfhydrase YP_002412933.1 2231929 R 585056 CDS YP_002412934.1 218705415 7158794 complement(2233020..2233820) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter; cystine transporter subunit 2233820 fliY 7158794 fliY Escherichia coli UMN026 cystine transporter subunit YP_002412934.1 2233020 R 585056 CDS YP_002412935.1 218705416 7156414 complement(2233908..2234459) 1 NC_011751.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2234459 fliZ 7156414 fliZ Escherichia coli UMN026 flagella biosynthesis protein FliZ YP_002412935.1 2233908 R 585056 CDS YP_002412936.1 218705417 7156415 complement(2234505..2235224) 1 NC_011751.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2235224 fliA 7156415 fliA Escherichia coli UMN026 flagellar biosynthesis sigma factor YP_002412936.1 2234505 R 585056 CDS YP_002412937.1 218705418 7156396 complement(2235544..2237208) 1 NC_011751.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin 2237208 7156396 ECUMN_2215 Escherichia coli UMN026 flagellin YP_002412937.1 2235544 R 585056 CDS YP_002412938.1 218705419 7155066 2237474..2238880 1 NC_011751.1 involved in flagellin assembly; flagellar capping protein 2238880 fliD 7155066 fliD Escherichia coli UMN026 flagellar capping protein YP_002412938.1 2237474 D 585056 CDS YP_002412939.1 218705420 7156397 2238905..2239315 1 NC_011751.1 flagellin specific chaperone; flagellar protein FliS 2239315 fliS 7156397 fliS Escherichia coli UMN026 flagellar protein FliS YP_002412939.1 2238905 D 585056 CDS YP_002412940.1 218705421 7156412 2239315..2239680 1 NC_011751.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2239680 fliT 7156412 fliT Escherichia coli UMN026 flagellar biosynthesis protein FliT YP_002412940.1 2239315 D 585056 CDS YP_002412941.1 218705422 7156413 2239758..2241245 1 NC_011751.1 converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2241245 amyA 7156413 amyA Escherichia coli UMN026 cytoplasmic alpha-amylase YP_002412941.1 2239758 D 585056 CDS YP_002412942.1 218705423 7155743 complement(2241279..2241692) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2241692 yedD 7155743 yedD Escherichia coli UMN026 hypothetical protein YP_002412942.1 2241279 R 585056 CDS YP_002412943.1 218705424 7158787 2241879..2243084 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; putative inner membrane protein 2243084 yedE 7158787 yedE Escherichia coli UMN026 putative inner membrane protein YP_002412943.1 2241879 D 585056 CDS YP_002412944.1 218705425 7158788 2243081..2243314 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2243314 yedF 7158788 yedF Escherichia coli UMN026 hypothetical protein YP_002412944.1 2243081 D 585056 CDS YP_002412945.1 218705426 7158789 2243421..2244089 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2244089 yedK 7158789 yedK Escherichia coli UMN026 hypothetical protein YP_002412945.1 2243421 D 585056 CDS YP_002412946.1 218705427 7158792 2244200..2244595 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 2244595 yedL 7158792 yedL Escherichia coli UMN026 putative acyltransferase YP_002412946.1 2244200 D 585056 CDS YP_002412947.1 218705428 7158793 complement(2244818..2245033) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2245033 7158793 ECUMN_2226 Escherichia coli UMN026 hypothetical protein YP_002412947.1 2244818 R 585056 CDS YP_002412948.1 218705429 7155067 complement(2245129..2245932) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2245932 7155067 ECUMN_2227 Escherichia coli UMN026 hypothetical protein YP_002412948.1 2245129 R 585056 CDS YP_002412949.1 218705430 7155068 complement(2246292..2246606) 1 NC_011751.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2246606 fliE 7155068 fliE Escherichia coli UMN026 flagellar hook-basal body protein FliE YP_002412949.1 2246292 R 585056 CDS YP_002412950.1 218705431 7156398 2246821..2248479 1 NC_011751.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2248479 fliF 7156398 fliF Escherichia coli UMN026 flagellar MS-ring protein YP_002412950.1 2246821 D 585056 CDS YP_002412951.1 218705432 7156399 2248472..2249467 1 NC_011751.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2249467 fliG 7156399 fliG Escherichia coli UMN026 flagellar motor switch protein G YP_002412951.1 2248472 D 585056 CDS YP_002412952.1 218705433 7156400 2249460..2250146 1 NC_011751.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2250146 fliH 7156400 fliH Escherichia coli UMN026 flagellar assembly protein H YP_002412952.1 2249460 D 585056 CDS YP_002412953.1 218705434 7156401 2250146..2251519 1 NC_011751.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2251519 fliI 7156401 fliI Escherichia coli UMN026 flagellum-specific ATP synthase YP_002412953.1 2250146 D 585056 CDS YP_002412954.1 218705435 7156402 2251538..2251981 1 NC_011751.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2251981 fliJ 7156402 fliJ Escherichia coli UMN026 flagellar biosynthesis chaperone YP_002412954.1 2251538 D 585056 CDS YP_002412955.1 218705436 7156403 2251978..2253105 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 8631687; Product type s : structure; flagellar hook-length control protein 2253105 fliK 7156403 fliK Escherichia coli UMN026 flagellar hook-length control protein YP_002412955.1 2251978 D 585056 CDS YP_002412956.1 218705437 7156404 2253210..2253674 1 NC_011751.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2253674 fliL 7156404 fliL Escherichia coli UMN026 flagellar basal body-associated protein FliL YP_002412956.1 2253210 D 585056 CDS YP_002412957.1 218705438 7156405 2253679..2254683 1 NC_011751.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2254683 fliM 7156405 fliM Escherichia coli UMN026 flagellar motor switch protein FliM YP_002412957.1 2253679 D 585056 CDS YP_002412958.1 218705439 7156406 2254680..2255093 1 NC_011751.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2255093 fliN 7156406 fliN Escherichia coli UMN026 flagellar motor switch protein FliN YP_002412958.1 2254680 D 585056 CDS YP_002412959.1 218705440 7156407 2255096..2255461 1 NC_011751.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2255461 fliO 7156407 fliO Escherichia coli UMN026 flagellar biosynthesis protein FliO YP_002412959.1 2255096 D 585056 CDS YP_002412960.1 218705441 7156408 2255461..2256198 1 NC_011751.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2256198 fliP 7156408 fliP Escherichia coli UMN026 flagellar biosynthesis protein FliP YP_002412960.1 2255461 D 585056 CDS YP_002412961.1 218705442 7156409 2256208..2256477 1 NC_011751.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2256477 fliQ 7156409 fliQ Escherichia coli UMN026 flagellar biosynthesis protein FliQ YP_002412961.1 2256208 D 585056 CDS YP_002412962.1 218705443 7156410 2256486..2257271 1 NC_011751.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2257271 fliR 7156410 fliR Escherichia coli UMN026 flagellar biosynthesis protein FliR YP_002412962.1 2256486 D 585056 CDS YP_002412963.1 218705444 7156411 2257561..2258184 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator; DNA-binding transcriptional activator, co-regulator with RcsB 2258184 rcsA 7156411 rcsA Escherichia coli UMN026 DNA-binding transcriptional activator, co-regulator with RcsB YP_002412963.1 2257561 D 585056 CDS YP_002412964.1 218705445 7157628 complement(2258228..2258416) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408; hypothetical protein 2258416 dsrB 7157628 dsrB Escherichia coli UMN026 hypothetical protein YP_002412964.1 2258228 R 585056 CDS YP_002412965.1 218705446 7156210 2258579..2258806 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2258806 yodD 7156210 yodD Escherichia coli UMN026 hypothetical protein YP_002412965.1 2258579 D 585056 CDS YP_002412966.1 218705447 7156208 2259104..2259919 1 NC_011751.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2259919 yedP 7156208 yedP Escherichia coli UMN026 mannosyl-3-phosphoglycerate phosphatase YP_002412966.1 2259104 D 585056 CDS YP_002412967.1 218705448 7158795 complement(2259916..2261610) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465; Product type pe : putative enzyme; putative diguanylate cyclase 2261610 yedQ 7158795 yedQ Escherichia coli UMN026 putative diguanylate cyclase YP_002412967.1 2259916 R 585056 CDS YP_002412968.1 218705449 7158796 complement(2261531..2261719) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2261719 7158796 ECUMN_2248 Escherichia coli UMN026 hypothetical protein YP_002412968.1 2261531 R 585056 CDS YP_002412969.1 218705450 7155069 complement(2261781..2261963) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2261963 yodC 7155069 yodC Escherichia coli UMN026 hypothetical protein YP_002412969.1 2261781 R 585056 CDS YP_002412970.1 218705451 7159555 complement(2262042..2262959) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2262959 yedI 7159555 yedI Escherichia coli UMN026 hypothetical protein YP_002412970.1 2262042 R 585056 CDS YP_002412971.1 218705452 7158790 2263132..2264052 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2264052 yedA 7158790 yedA Escherichia coli UMN026 hypothetical protein YP_002412971.1 2263132 D 585056 CDS YP_002412972.1 218705453 7158786 complement(2264041..2264511) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme; DNA mismatch endonuclease of very short patch repair 2264511 vsr 7158786 vsr Escherichia coli UMN026 DNA mismatch endonuclease of very short patch repair YP_002412972.1 2264041 R 585056 CDS YP_002412973.1 218705454 7158212 complement(2264492..2265910) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90280700, 91285397, 93367813, 2198248, 2527357; Product type e : enzyme; DNA cytosine methylase 2265910 dcm 7158212 dcm Escherichia coli UMN026 DNA cytosine methylase YP_002412973.1 2264492 R 585056 CDS YP_002412974.1 218705455 7156114 complement(2265977..2266672) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme; hypothetical protein 2266672 yedJ 7156114 yedJ Escherichia coli UMN026 hypothetical protein YP_002412974.1 2265977 R 585056 CDS YP_002412975.1 218705456 7158791 complement(2266712..2267077) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2267077 yedR 7158791 yedR Escherichia coli UMN026 hypothetical protein YP_002412975.1 2266712 R 585056 CDS YP_002412976.1 218705457 7157795 2267613..2268821 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9642192; Product type m : membrane component; porin OmpN 2268821 7157795 ECUMN_2256 Escherichia coli UMN026 porin OmpN YP_002412976.1 2267613 D 585056 CDS YP_002412977.1 218705458 7155070 2269413..2270264 1 NC_011751.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2270264 hchA 7155070 hchA Escherichia coli UMN026 chaperone protein HchA YP_002412977.1 2269413 D 585056 CDS YP_002412978.1 218705459 7156640 complement(2270372..2271730) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865; Product type rc : receptor; sensory kinase in two-component regulatory system with YedW 2271730 yedV 7156640 yedV Escherichia coli UMN026 sensory kinase in two-component regulatory system with YedW YP_002412978.1 2270372 R 585056 CDS YP_002412979.1 218705460 7158798 complement(2271730..2272401) 1 NC_011751.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW 2272401 yedW 7158798 yedW Escherichia coli UMN026 transcriptional regulatory protein YedW YP_002412979.1 2271730 R 585056 CDS YP_002412980.1 218705461 7158799 2272534..2272947 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2272947 yedX 7158799 yedX Escherichia coli UMN026 hypothetical protein YP_002412980.1 2272534 D 585056 CDS YP_002412981.1 218705462 7158800 2273056..2274060 1 NC_011751.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 2274060 yedY 7158800 yedY Escherichia coli UMN026 putative sulfite oxidase subunit YedY YP_002412981.1 2273056 D 585056 CDS YP_002412982.1 218705463 7158801 2274061..2274696 1 NC_011751.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2274696 yedZ 7158801 yedZ Escherichia coli UMN026 putative sulfite oxidase subunit YedZ YP_002412982.1 2274061 D 585056 CDS YP_002412983.1 218705464 7158802 2274953..2275603 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12077457, 12480884, 12909634, 9579078; hypothetical protein 2275603 yodA 7158802 yodA Escherichia coli UMN026 hypothetical protein YP_002412983.1 2274953 D 585056 CDS YP_002412984.1 218705465 7155635 2276457..2277254 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2277254 yeeI 7155635 yeeI Escherichia coli UMN026 hypothetical protein YP_002412984.1 2276457 D 585056 CDS YP_002412985.1 218705466 7155573 2277592..2278854 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase 2278854 int 7155573 int Escherichia coli UMN026 integrase YP_002412985.1 2277592 D 585056 CDS YP_002412986.1 218705467 7156842 complement(2279048..2280352) 1 NC_011751.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 2280352 irp 7156842 irp Escherichia coli UMN026 salicylate synthase Irp9 YP_002412986.1 2279048 R 585056 CDS YP_002412987.1 218705468 7156847 complement(2280380..2281783) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; yersiniabactin-iron transporter permease YbtX 2281783 irp 7156847 irp Escherichia coli UMN026 yersiniabactin-iron transporter permease YbtX YP_002412987.1 2280380 R 585056 CDS YP_002412988.1 218705469 7156848 complement(2281653..2283482) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter; yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtQ 2283482 irp 7156848 irp Escherichia coli UMN026 yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtQ YP_002412988.1 2281653 R 585056 CDS YP_002412989.1 218705470 7156849 complement(2283442..2285244) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter; yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtP 2285244 irp 7156849 irp Escherichia coli UMN026 yersiniabactin-iron ABC transporter permease and ATP-binding protein YbtP YP_002412989.1 2283442 R 585056 CDS YP_002412990.1 218705471 7156850 2285411..2286370 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8930916; Product type r : regulator; AraC family transcriptional regulator 2286370 ybtA 7156850 ybtA Escherichia coli UMN026 AraC family transcriptional regulator YP_002412990.1 2285411 D 585056 CDS YP_002412991.1 218705472 7158487 2286543..2292668 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 8366034, 11927258, 9709002; Product type e : enzyme; High-molecular-weight nonribosomal peptide/polyketide synthetase 2 2292668 irp 7158487 irp Escherichia coli UMN026 High-molecular-weight nonribosomal peptide/polyketide synthetase 2 YP_002412991.1 2286543 D 585056 CDS YP_002412992.1 218705473 7156851 2292756..2302247 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 11927258; Product type e : enzyme; High-molecular-weight nonribosomal peptide/polyketide synthetase 1 2302247 irp 7156851 irp Escherichia coli UMN026 High-molecular-weight nonribosomal peptide/polyketide synthetase 1 YP_002412992.1 2292756 D 585056 CDS YP_002412993.1 218705474 7156852 2302184..2303344 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme; Thiazolinyl-S-HMWP1 reductase YbtU 2303344 irp 7156852 irp Escherichia coli UMN026 Thiazolinyl-S-HMWP1 reductase YbtU YP_002412993.1 2302184 D 585056 CDS YP_002412994.1 218705475 7156853 2303341..2304144 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioesterase YbtT 2304144 irp 7156853 irp Escherichia coli UMN026 putative thioesterase YbtT YP_002412994.1 2303341 D 585056 CDS YP_002412995.1 218705476 7156854 2304148..2305725 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9818149, 11927258, 9709002; Product type e : enzyme; salicyl-AMP ligase YbtE 2305725 irp 7156854 irp Escherichia coli UMN026 salicyl-AMP ligase YbtE YP_002412995.1 2304148 D 585056 CDS YP_002412996.1 218705477 7156855 2305856..2307877 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7896707, 7984105; Product type rc : receptor; Yersiniabactin/pesticin outer membrane receptor (IRPC) 2307877 fyuA 7156855 fyuA Escherichia coli UMN026 Yersiniabactin/pesticin outer membrane receptor (IRPC) YP_002412996.1 2305856 D 585056 CDS YP_002412997.1 218705478 7156482 2308691..2309674 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2309674 7156482 ECUMN_2279 Escherichia coli UMN026 hypothetical protein YP_002412997.1 2308691 D 585056 CDS YP_002412998.1 218705479 7155071 2310018..2310203 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2310203 7155071 ECUMN_2280 Escherichia coli UMN026 hypothetical protein YP_002412998.1 2310018 D 585056 CDS YP_002412999.1 218705480 7155072 2310188..2310769 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2310769 7155072 ECUMN_2281 Escherichia coli UMN026 hypothetical protein YP_002412999.1 2310188 D 585056 CDS YP_002413000.1 218705481 7155073 2310759..2310968 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative lambdoid prophage protein 2310968 7155073 ECUMN_2282 Escherichia coli UMN026 putative lambdoid prophage protein YP_002413000.1 2310759 D 585056 CDS YP_002413001.1 218705482 7155074 2311211..2311339 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2311339 7155074 ECUMN_2283 Escherichia coli UMN026 hypothetical protein YP_002413001.1 2311211 D 585056 CDS YP_002413002.1 218705483 7155075 2312196..2312924 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB1 component 2312924 7155075 ECUMN_2284 Escherichia coli UMN026 putative type IV secretory pathway VirB1 component YP_002413002.1 2312196 D 585056 CDS YP_002413003.1 218705484 7155076 2312924..2313217 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB2 component 2313217 7155076 ECUMN_2285 Escherichia coli UMN026 putative type IV secretory pathway VirB2 component YP_002413003.1 2312924 D 585056 CDS YP_002413004.1 218705485 7155077 2313230..2315968 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB4 component 2315968 7155077 ECUMN_2286 Escherichia coli UMN026 putative type IV secretory pathway VirB4 component YP_002413004.1 2313230 D 585056 CDS YP_002413005.1 218705486 7155078 2315987..2316700 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB5 component 2316700 7155078 ECUMN_2287 Escherichia coli UMN026 putative type IV secretory pathway VirB5 component YP_002413005.1 2315987 D 585056 CDS YP_002413006.1 218705487 7155079 2316708..2316950 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283, 15546668, 16428391; hypothetical protein 2316950 7155079 ECUMN_2288 Escherichia coli UMN026 hypothetical protein YP_002413006.1 2316708 D 585056 CDS YP_002413007.1 218705488 7155080 2316954..2317298 1 NC_011751.1 Evidence 7 : Gene remnant; Product type m : membrane component; type IV secretory pathway VirB6 component (fragment) 2317298 7155080 ECUMN_2289 Escherichia coli UMN026 type IV secretory pathway VirB6 component (fragment) YP_002413007.1 2316954 D 585056 CDS YP_002413008.1 218705489 7155081 complement(2317336..2318352) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 2318352 insH 7155081 insH Escherichia coli UMN026 IS5 transposase and trans-activator; CP4-44 prophage YP_002413008.1 2317336 R 585056 CDS YP_002413009.1 218705490 7156831 2318315..2319226 1 NC_011751.1 Evidence 7 : Gene remnant; Product type m : membrane component; type IV secretory pathway VirB6 component (fragment) 2319226 7156831 ECUMN_2291 Escherichia coli UMN026 type IV secretory pathway VirB6 component (fragment) YP_002413009.1 2318315 D 585056 CDS YP_002413010.1 218705491 7155082 2319444..2320127 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB8 component 2320127 7155082 ECUMN_2292 Escherichia coli UMN026 putative type IV secretory pathway VirB8 component YP_002413010.1 2319444 D 585056 CDS YP_002413011.1 218705492 7155083 2320124..2321032 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB9 component 2321032 7155083 ECUMN_2293 Escherichia coli UMN026 putative type IV secretory pathway VirB9 component YP_002413011.1 2320124 D 585056 CDS YP_002413012.1 218705493 7155084 2321070..2322338 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure; putative type IV secretory pathway VirB10 component 2322338 7155084 ECUMN_2294 Escherichia coli UMN026 putative type IV secretory pathway VirB10 component YP_002413012.1 2321070 D 585056 CDS YP_002413013.1 218705494 7155085 2322328..2323353 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391, 2370849, 2233252; Product type ps : putative structure; putative type IV secretory pathway VirB11 component 2323353 7155085 ECUMN_2295 Escherichia coli UMN026 putative type IV secretory pathway VirB11 component YP_002413013.1 2322328 D 585056 CDS YP_002413014.1 218705495 7155087 2323789..2324091 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; kikA from plasmid origin 2324091 7155087 ECUMN_2297 Escherichia coli UMN026 kikA from plasmid origin YP_002413014.1 2323789 D 585056 CDS YP_002413015.1 218705496 7155088 2324136..2324441 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283; hypothetical protein 2324441 7155088 ECUMN_2298 Escherichia coli UMN026 hypothetical protein YP_002413015.1 2324136 D 585056 CDS YP_002413016.1 218705497 7155089 2325151..2327010 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031; Product type h : extrachromosomal origin; putative MobB mobilization protein 2327010 7155089 ECUMN_2299 Escherichia coli UMN026 putative MobB mobilization protein YP_002413016.1 2325151 D 585056 CDS YP_002413017.1 218705498 7155090 2327014..2327766 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031, 11251827; Product type h : extrachromosomal origin; putative MobC mobilization protein 2327766 7155090 ECUMN_2300 Escherichia coli UMN026 putative MobC mobilization protein YP_002413017.1 2327014 D 585056 CDS YP_002413018.1 218705499 7155091 complement(2327959..2329098) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10686096; Product type pc : putative carrier; putative Antirestriction protein ardC 2329098 7155091 ECUMN_2301 Escherichia coli UMN026 putative Antirestriction protein ardC YP_002413018.1 2327959 R 585056 CDS YP_002413019.1 218705500 7155092 2329140..2329373 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2329373 7155092 ECUMN_2302 Escherichia coli UMN026 hypothetical protein YP_002413019.1 2329140 D 585056 CDS YP_002413020.1 218705501 7155093 2329496..2329807 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2329807 7155093 ECUMN_2303 Escherichia coli UMN026 hypothetical protein YP_002413020.1 2329496 D 585056 CDS YP_002413021.1 218705502 7155094 2329909..2330904 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2330904 7155094 ECUMN_2304 Escherichia coli UMN026 hypothetical protein YP_002413021.1 2329909 D 585056 CDS YP_002413022.1 218705503 7155095 2330901..2331989 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2331989 7155095 ECUMN_2305 Escherichia coli UMN026 hypothetical protein YP_002413022.1 2330901 D 585056 CDS YP_002413023.1 218705504 7155096 2331974..2332480 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2332480 7155096 ECUMN_2306 Escherichia coli UMN026 hypothetical protein YP_002413023.1 2331974 D 585056 CDS YP_002413024.1 218705505 7155097 2332477..2334357 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2334357 7155097 ECUMN_2307 Escherichia coli UMN026 hypothetical protein YP_002413024.1 2332477 D 585056 CDS YP_002413025.1 218705506 7155098 complement(2334641..2335660) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2335660 7155098 ECUMN_2308 Escherichia coli UMN026 hypothetical protein YP_002413025.1 2334641 R 585056 CDS YP_002413026.1 218705507 7155099 complement(2335692..2335829) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2335829 7155099 ECUMN_2309 Escherichia coli UMN026 hypothetical protein YP_002413026.1 2335692 R 585056 CDS YP_002413027.1 218705508 7155100 2337029..2339305 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2339305 7155100 ECUMN_2310 Escherichia coli UMN026 hypothetical protein YP_002413027.1 2337029 D 585056 CDS YP_002413028.1 218705509 7155101 2339420..2340520 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Retron-type reverse transcriptase 2340520 7155101 ECUMN_2312 Escherichia coli UMN026 putative Retron-type reverse transcriptase YP_002413028.1 2339420 D 585056 CDS YP_002413029.1 218705510 7155102 complement(2341176..2341670) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2341670 7155102 ECUMN_2313 Escherichia coli UMN026 hypothetical protein YP_002413029.1 2341176 R 585056 CDS YP_002413030.1 218705511 7155103 complement(2342042..2342320) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2342320 7155103 ECUMN_2314 Escherichia coli UMN026 hypothetical protein YP_002413030.1 2342042 R 585056 CDS YP_002413031.1 218705512 7155104 complement(2342428..2342571) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2342571 7155104 ECUMN_2315 Escherichia coli UMN026 hypothetical protein YP_002413031.1 2342428 R 585056 CDS YP_002413032.1 218705513 7155105 complement(2342466..2342945) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase 2342945 7155105 ECUMN_2316 Escherichia coli UMN026 putative transposase YP_002413032.1 2342466 R 585056 CDS YP_002413033.1 218705514 7155106 2343400..2351457 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component; putative invasin 2351457 7155106 ECUMN_2317 Escherichia coli UMN026 putative invasin YP_002413033.1 2343400 D 585056 CDS YP_002413034.1 218705515 7155107 complement(2351719..2352771) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2352771 7155107 ECUMN_2318 Escherichia coli UMN026 hypothetical protein YP_002413034.1 2351719 R 585056 CDS YP_002413035.1 218705516 7155108 2353086..2354402 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter; shikimate transporter 2354402 shiA 7155108 shiA Escherichia coli UMN026 shikimate transporter YP_002413035.1 2353086 D 585056 CDS YP_002413036.1 218705517 7157923 2354504..2355958 1 NC_011751.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2355958 amn 7157923 amn Escherichia coli UMN026 AMP nucleosidase YP_002413036.1 2354504 D 585056 CDS YP_002413037.1 218705518 7155736 2356300..2357016 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2357016 yeeN 7155736 yeeN Escherichia coli UMN026 hypothetical protein YP_002413037.1 2356300 D 585056 CDS YP_002413038.1 218705519 7158806 2357252..2357431 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2357431 7158806 ECUMN_2322 Escherichia coli UMN026 hypothetical protein YP_002413038.1 2357252 D 585056 CDS YP_002413039.1 218705520 7155634 complement(2357647..2359287) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : putative transporter; hypothetical protein 2359287 yeeO 7155634 yeeO Escherichia coli UMN026 hypothetical protein YP_002413039.1 2357647 R 585056 CDS YP_002413040.1 218705521 7155574 complement(2359408..2360358) 1 NC_011751.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2360358 cbl 7155574 cbl Escherichia coli UMN026 transcriptional regulator Cbl YP_002413040.1 2359408 R 585056 CDS YP_002413041.1 218705522 7155921 complement(2360460..2361377) 1 NC_011751.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2361377 nac 7155921 nac Escherichia coli UMN026 nitrogen assimilation transcriptional regulator YP_002413041.1 2360460 R 585056 CDS YP_002413042.1 218705523 7155575 complement(2361834..2362766) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein 2362766 erfK 7155575 erfK Escherichia coli UMN026 hypothetical protein YP_002413042.1 2361834 R 585056 CDS YP_002413043.1 218705524 7156268 complement(2362831..2363910) 1 NC_011751.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2363910 cobT 7156268 cobT Escherichia coli UMN026 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_002413043.1 2362831 R 585056 CDS YP_002413044.1 218705525 7155993 complement(2363922..2364665) 1 NC_011751.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 2364665 cobS 7155993 cobS Escherichia coli UMN026 cobalamin synthase YP_002413044.1 2363922 R 585056 CDS YP_002413045.1 218705526 7155992 complement(2364662..2365207) 1 NC_011751.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 2365207 cobU 7155992 cobU Escherichia coli UMN026 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase YP_002413045.1 2364662 R 585056 CDS YP_002413046.1 218705527 7155994 complement(2365340..2365846) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative Cobalamin biosynthesis protein CbiG 2365846 7155994 ECUMN_2330 Escherichia coli UMN026 putative Cobalamin biosynthesis protein CbiG YP_002413046.1 2365340 R 585056 CDS YP_002413047.1 218705528 7155110 2365994..2366170 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2366170 7155110 ECUMN_2331 Escherichia coli UMN026 hypothetical protein YP_002413047.1 2365994 D 585056 CDS YP_002413048.1 218705529 7155111 complement(2366262..2367176) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8071226; Product type f : factor; propanediol utilization: transcriptional regulation 2367176 pocR 7155111 pocR Escherichia coli UMN026 propanediol utilization: transcriptional regulation YP_002413048.1 2366262 R 585056 CDS YP_002413049.1 218705530 7157484 complement(2367379..2368227) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9352910; Product type m : membrane component; propanediol diffusion facilitator 2368227 pduF 7157484 pduF Escherichia coli UMN026 propanediol diffusion facilitator YP_002413049.1 2367379 R 585056 CDS YP_002413050.1 218705531 7157403 2368700..2368984 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduA-like protein 2368984 7157403 ECUMN_2334 Escherichia coli UMN026 putative propanediol utilization polyhedral bodies PduA-like protein YP_002413050.1 2368700 D 585056 CDS YP_002413051.1 218705532 7155112 2368981..2369793 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduB 2369793 7155112 ECUMN_2335 Escherichia coli UMN026 putative propanediol utilization polyhedral bodies PduB YP_002413051.1 2368981 D 585056 CDS YP_002413052.1 218705533 7155113 2369812..2371476 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; glycerol dehydratase large subunit 2371476 pduC 7155113 pduC Escherichia coli UMN026 glycerol dehydratase large subunit YP_002413052.1 2369812 D 585056 CDS YP_002413053.1 218705534 7157400 2371486..2372154 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7706251, 12788698; Product type e : enzyme; propanediol utilization: diol dehydratase, medium subunit 2372154 PduD 7157400 PduD Escherichia coli UMN026 propanediol utilization: diol dehydratase, medium subunit YP_002413053.1 2371486 D 585056 CDS YP_002413054.1 218705535 7157401 2372169..2372687 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; propanediol utilization diol dehydratase, small subunit 2372687 pduE 7157401 pduE Escherichia coli UMN026 propanediol utilization diol dehydratase, small subunit YP_002413054.1 2372169 D 585056 CDS YP_002413055.1 218705536 7157402 2372697..2374529 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708, 12788698; Product type pe : putative enzyme; putative propanediol utilization diol dehydratase reactivation PduG 2374529 7157402 ECUMN_2339 Escherichia coli UMN026 putative propanediol utilization diol dehydratase reactivation PduG YP_002413055.1 2372697 D 585056 CDS YP_002413056.1 218705537 7155114 2374519..2374869 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diol dehydratase reactivation pduH 2374869 7155114 ECUMN_2340 Escherichia coli UMN026 putative diol dehydratase reactivation pduH YP_002413056.1 2374519 D 585056 CDS YP_002413057.1 218705538 7155116 2375188..2375610 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduK 2375610 7155116 ECUMN_2342 Escherichia coli UMN026 putative propanediol utilization protein PduK YP_002413057.1 2375188 D 585056 CDS YP_002413058.1 218705539 7155117 2375613..2376245 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduL 2376245 7155117 ECUMN_2343 Escherichia coli UMN026 putative propanediol utilization protein PduL YP_002413058.1 2375613 D 585056 CDS YP_002413059.1 218705540 7155118 2376242..2376733 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization pduM 2376733 7155118 ECUMN_2344 Escherichia coli UMN026 putative propanediol utilization pduM YP_002413059.1 2376242 D 585056 CDS YP_002413060.1 218705541 7155119 2376737..2377012 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduN 2377012 7155119 ECUMN_2345 Escherichia coli UMN026 putative propanediol utilization polyhedral bodies PduN YP_002413060.1 2376737 D 585056 CDS YP_002413061.1 218705542 7155120 2377024..2378031 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization B12-like protein 2378031 7155120 ECUMN_2346 Escherichia coli UMN026 putative propanediol utilization B12-like protein YP_002413061.1 2377024 D 585056 CDS YP_002413062.1 218705543 7155121 2378028..2379413 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : putative enzyme; putative CoA-dependent proprionaldehyde dehydrogenase pduP 2379413 7155121 ECUMN_2347 Escherichia coli UMN026 putative CoA-dependent proprionaldehyde dehydrogenase pduP YP_002413062.1 2378028 D 585056 CDS YP_002413063.1 218705544 7155122 2379424..2380536 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : putative enzyme; putative propanediol utilization propanol dehydrogenase pduQ 2380536 7155122 ECUMN_2348 Escherichia coli UMN026 putative propanediol utilization propanol dehydrogenase pduQ YP_002413063.1 2379424 D 585056 CDS YP_002413064.1 218705545 7155123 2380533..2381876 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization ferredoxin PduS 2381876 7155123 ECUMN_2349 Escherichia coli UMN026 putative propanediol utilization ferredoxin PduS YP_002413064.1 2380533 D 585056 CDS YP_002413065.1 218705546 7155124 2381879..2382433 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduT 2382433 7155124 ECUMN_2350 Escherichia coli UMN026 putative propanediol utilization polyhedral bodies PduT YP_002413065.1 2381879 D 585056 CDS YP_002413066.1 218705547 7155125 2382409..2382783 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure; putative propanediol utilization polyhedral bodies PduU 2382783 7155125 ECUMN_2351 Escherichia coli UMN026 putative propanediol utilization polyhedral bodies PduU YP_002413066.1 2382409 D 585056 CDS YP_002413067.1 218705548 7155126 2382788..2383231 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative propanediol utilization protein PduV 2383231 7155126 ECUMN_2352 Escherichia coli UMN026 putative propanediol utilization protein PduV YP_002413067.1 2382788 D 585056 CDS YP_002413068.1 218705549 7155127 complement(2383332..2383727) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2383727 yeeX 7155127 yeeX Escherichia coli UMN026 hypothetical protein YP_002413068.1 2383332 R 585056 CDS YP_002413069.1 218705550 7158813 complement(2383833..2384891) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2384891 yeeA 7158813 yeeA Escherichia coli UMN026 hypothetical protein YP_002413069.1 2383833 R 585056 CDS YP_002413070.1 218705551 7158803 complement(2385090..2385563) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11850398, 9442027, 8709849; Product type r : regulator; DNA gyrase inhibitor 2385563 sbmC 7158803 sbmC Escherichia coli UMN026 DNA gyrase inhibitor YP_002413070.1 2385090 R 585056 CDS YP_002413071.1 218705552 7157875 complement(2385682..2386848) 1 NC_011751.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 2386848 dacD 7157875 dacD Escherichia coli UMN026 D-alanyl-D-alanine carboxypeptidase YP_002413071.1 2385682 R 585056 CDS YP_002413072.1 218705553 7156102 2387057..2388484 1 NC_011751.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2388484 sbcB 7156102 sbcB Escherichia coli UMN026 exonuclease I YP_002413072.1 2387057 D 585056 CDS YP_002413073.1 218705554 7157871 complement(2388559..2389917) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative amino-acid/amine transporter 2389917 yeeF 7157871 yeeF Escherichia coli UMN026 putative amino-acid/amine transporter YP_002413073.1 2388559 R 585056 CDS YP_002413074.1 218705555 7158804 complement(2390184..2391113) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2391113 yeeY 7158804 yeeY Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413074.1 2390184 R 585056 CDS YP_002413075.1 218705556 7158814 complement(2391159..2391983) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative epimerase, with NAD(P)-binding Rossmann-fold domain 2391983 yeeZ 7158814 yeeZ Escherichia coli UMN026 putative epimerase, with NAD(P)-binding Rossmann-fold domain YP_002413075.1 2391159 R 585056 CDS YP_002413077.1 218705558 7156682 2392606..2393505 1 NC_011751.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2393505 hisG 7156682 hisG Escherichia coli UMN026 ATP phosphoribosyltransferase YP_002413077.1 2392606 D 585056 CDS YP_002413078.1 218705559 7156678 2393511..2394815 1 NC_011751.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2394815 hisD 7156678 hisD Escherichia coli UMN026 histidinol dehydrogenase YP_002413078.1 2393511 D 585056 CDS YP_002413079.1 218705560 7156676 2394812..2395882 1 NC_011751.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2395882 hisC 7156676 hisC Escherichia coli UMN026 histidinol-phosphate aminotransferase YP_002413079.1 2394812 D 585056 CDS YP_002413080.1 218705561 7156675 2395882..2396949 1 NC_011751.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2396949 hisB 7156675 hisB Escherichia coli UMN026 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002413080.1 2395882 D 585056 CDS YP_002413081.1 218705562 7156674 2396949..2397539 1 NC_011751.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2397539 hisH 7156674 hisH Escherichia coli UMN026 imidazole glycerol phosphate synthase subunit HisH YP_002413081.1 2396949 D 585056 CDS YP_002413082.1 218705563 7156679 2397539..2398276 1 NC_011751.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2398276 hisA 7156679 hisA Escherichia coli UMN026 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002413082.1 2397539 D 585056 CDS YP_002413083.1 218705564 7156673 2398258..2399034 1 NC_011751.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2399034 hisF 7156673 hisF Escherichia coli UMN026 imidazole glycerol phosphate synthase subunit HisF YP_002413083.1 2398258 D 585056 CDS YP_002413084.1 218705565 7156677 2399028..2399639 1 NC_011751.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2399639 hisI 7156677 hisI Escherichia coli UMN026 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein YP_002413084.1 2399028 D 585056 CDS YP_002413085.1 218705566 7156680 complement(2399822..2400802) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98241528; Product type r : regulator; regulator of length of O-antigen component of lipopolysaccharide chains 2400802 cld 7156680 cld Escherichia coli UMN026 regulator of length of O-antigen component of lipopolysaccharide chains YP_002413085.1 2399822 R 585056 CDS YP_002413086.1 218705567 7155977 complement(2400945..2402111) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme; UDP-glucose 6-dehydrogenase 2402111 ugd 7155977 ugd Escherichia coli UMN026 UDP-glucose 6-dehydrogenase YP_002413086.1 2400945 R 585056 CDS YP_002413087.1 218705568 7158164 complement(2402361..2403767) 1 NC_011751.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2403767 gnd 7158164 gnd Escherichia coli UMN026 6-phosphogluconate dehydrogenase YP_002413087.1 2402361 R 585056 CDS YP_002413088.1 218705569 7156592 complement(2403920..2405155) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative O antigen transporter Wzx 2405155 7156592 ECUMN_2372 Escherichia coli UMN026 putative O antigen transporter Wzx YP_002413088.1 2403920 R 585056 CDS YP_002413089.1 218705570 7155128 complement(2405197..2406528) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative O antigen polymerase wzy 2406528 7155128 ECUMN_2373 Escherichia coli UMN026 putative O antigen polymerase wzy YP_002413089.1 2405197 R 585056 CDS YP_002413090.1 218705571 7155129 complement(2406712..2408175) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Phosphomannomutase (PMM) 2408175 manB 7155129 manB Escherichia coli UMN026 Phosphomannomutase (PMM) YP_002413090.1 2406712 R 585056 CDS YP_002413091.1 218705572 7157055 complement(2408144..2409559) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; mannose-1-phosphate guanyltransferase 2409559 cpsB 7157055 cpsB Escherichia coli UMN026 mannose-1-phosphate guanyltransferase YP_002413091.1 2408144 R 585056 CDS YP_002413092.1 218705573 7156002 complement(2409561..2410763) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Mannosyl transferase wbaD 2410763 wbaD 7156002 wbaD Escherichia coli UMN026 Mannosyl transferase wbaD YP_002413092.1 2409561 R 585056 CDS YP_002413093.1 218705574 7158222 complement(2410756..2411793) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Mannosyl transferase WbaC 2411793 wbaC 7158222 wbaC Escherichia coli UMN026 Mannosyl transferase WbaC YP_002413093.1 2410756 R 585056 CDS YP_002413094.1 218705575 7158221 complement(2412154..2413047) 1 NC_011751.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2413047 galF 7158221 galF Escherichia coli UMN026 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_002413094.1 2412154 R 585056 CDS YP_002413095.1 218705576 7156494 complement(2413222..2414616) 1 NC_011751.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein 2414616 wcaM 7156494 wcaM Escherichia coli UMN026 putative colanic acid biosynthesis protein YP_002413095.1 2413222 R 585056 CDS YP_002413096.1 218705577 7158233 complement(2414627..2415847) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase 2415847 wcaL 7158233 wcaL Escherichia coli UMN026 putative glycosyl transferase YP_002413096.1 2414627 R 585056 CDS YP_002413097.1 218705578 7158232 complement(2415844..2417124) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : putative enzyme; putative pyruvyl transferase 2417124 wcaK 7158232 wcaK Escherichia coli UMN026 putative pyruvyl transferase YP_002413097.1 2415844 R 585056 CDS YP_002413098.1 218705579 7158231 complement(2417400..2418878) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : putative transporter; colanic acid exporter 2418878 wzxC 7158231 wzxC Escherichia coli UMN026 colanic acid exporter YP_002413098.1 2417400 R 585056 CDS YP_002413099.1 218705580 7158238 complement(2418880..2420274) 1 NC_011751.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase 2420274 wcaJ 7158238 wcaJ Escherichia coli UMN026 putative UDP-glucose lipid carrier transferase YP_002413099.1 2418880 R 585056 CDS YP_002413100.1 218705581 7158230 complement(2420329..2421699) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase 2421699 cpsG 7158230 cpsG Escherichia coli UMN026 phosphomannomutase YP_002413100.1 2420329 R 585056 CDS YP_002413101.1 218705582 7156004 complement(2421892..2423328) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme; mannose-1-phosphate guanyltransferase 2423328 cpsB 7156004 cpsB Escherichia coli UMN026 mannose-1-phosphate guanyltransferase YP_002413101.1 2421892 R 585056 CDS YP_002413102.1 218705583 7156003 complement(2423331..2424554) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : putative enzyme; putative glycosyl transferase 2424554 wcaI 7156003 wcaI Escherichia coli UMN026 putative glycosyl transferase YP_002413102.1 2423331 R 585056 CDS YP_002413103.1 218705584 7158229 complement(2424551..2425030) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase 2425030 nudD 7158229 nudD Escherichia coli UMN026 GDP-mannose mannosyl hydrolase YP_002413103.1 2424551 R 585056 CDS YP_002413104.1 218705585 7157318 complement(2425033..2425998) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase 2425998 fcl 7157318 fcl Escherichia coli UMN026 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase YP_002413104.1 2425033 R 585056 CDS YP_002413105.1 218705586 7156312 complement(2426001..2427122) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase 2427122 gmd 7156312 gmd Escherichia coli UMN026 GDP-D-mannose dehydratase YP_002413105.1 2426001 R 585056 CDS YP_002413106.1 218705587 7156588 complement(2427149..2427697) 1 NC_011751.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF 2427697 wcaF 7156588 wcaF Escherichia coli UMN026 putative colanic acid biosynthesis acetyltransferase WcaF YP_002413106.1 2427149 R 585056 CDS YP_002413107.1 218705588 7158228 complement(2427713..2428459) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : putative enzyme; putative glycosyl transferase 2428459 wcaE 7158228 wcaE Escherichia coli UMN026 putative glycosyl transferase YP_002413107.1 2427713 R 585056 CDS YP_002413108.1 218705589 7158227 complement(2428470..2429687) 1 NC_011751.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein 2429687 wcaD 7158227 wcaD Escherichia coli UMN026 putative colanic acid biosynthesis protein YP_002413108.1 2428470 R 585056 CDS YP_002413109.1 218705590 7158226 complement(2429662..2430879) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase 2430879 wcaC 7158226 wcaC Escherichia coli UMN026 putative glycosyl transferase YP_002413109.1 2429662 R 585056 CDS YP_002413110.1 218705591 7158225 complement(2430876..2431364) 1 NC_011751.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB 2431364 wcaB 7158225 wcaB Escherichia coli UMN026 putative colanic acid biosynthesis acetyltransferase WcaB YP_002413110.1 2430876 R 585056 CDS YP_002413111.1 218705592 7158224 complement(2431367..2432206) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme; putative glycosyl transferase 2432206 wcaA 7158224 wcaA Escherichia coli UMN026 putative glycosyl transferase YP_002413111.1 2431367 R 585056 CDS YP_002413112.1 218705593 7158223 complement(2432299..2434461) 1 NC_011751.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2434461 wzc 7158223 wzc Escherichia coli UMN026 tyrosine kinase YP_002413112.1 2432299 R 585056 CDS YP_002413113.1 218705594 7158237 complement(2434464..2434907) 1 NC_011751.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2434907 wzb 7158237 wzb Escherichia coli UMN026 tyrosine phosphatase YP_002413113.1 2434464 R 585056 CDS YP_002413114.1 218705595 7158236 complement(2434913..2436052) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein; lipoprotein 2436052 wza 7158236 wza Escherichia coli UMN026 lipoprotein YP_002413114.1 2434913 R 585056 CDS YP_002413115.1 218705596 7158235 2436711..2438294 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 2438294 yegH 7158235 yegH Escherichia coli UMN026 hypothetical protein YP_002413115.1 2436711 D 585056 CDS YP_002413116.1 218705597 7158818 2438369..2438707 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438707 7158818 ECUMN_2400 Escherichia coli UMN026 hypothetical protein YP_002413116.1 2438369 D 585056 CDS YP_002413117.1 218705598 7155137 2438679..2438987 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438987 7155137 ECUMN_2401 Escherichia coli UMN026 hypothetical protein YP_002413117.1 2438679 D 585056 CDS YP_002413118.1 218705599 7155138 complement(2439040..2440893) 1 NC_011751.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein 2440893 asmA 7155138 asmA Escherichia coli UMN026 putative assembly protein YP_002413118.1 2439040 R 585056 CDS YP_002413119.1 218705600 7155812 complement(2440915..2441496) 1 NC_011751.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2441496 dcd 7155812 dcd Escherichia coli UMN026 deoxycytidine triphosphate deaminase YP_002413119.1 2440915 R 585056 CDS YP_002413120.1 218705601 7156113 complement(2441588..2442229) 1 NC_011751.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2442229 udk 7156113 udk Escherichia coli UMN026 uridine kinase YP_002413120.1 2441588 R 585056 CDS YP_002413121.1 218705602 7158162 2442547..2445864 1 NC_011751.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2445864 yegE 7158162 yegE Escherichia coli UMN026 putative sensor protein YP_002413121.1 2442547 D 585056 CDS YP_002413122.1 218705603 7158817 complement(2445902..2446759) 1 NC_011751.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase II 2446759 alkA 7158817 alkA Escherichia coli UMN026 3-methyl-adenine DNA glycosylase II YP_002413122.1 2445902 R 585056 CDS YP_002413123.1 218705604 7155724 2446893..2448245 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : putative factor; putative chaperone 2448245 yegD 7155724 yegD Escherichia coli UMN026 putative chaperone YP_002413123.1 2446893 D 585056 CDS YP_002413124.1 218705605 7158816 complement(2448258..2450204) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2450204 yegI 7158816 yegI Escherichia coli UMN026 hypothetical protein YP_002413124.1 2448258 R 585056 CDS YP_002413125.1 218705606 7158819 2450405..2450866 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2450866 yegJ 7158819 yegJ Escherichia coli UMN026 hypothetical protein YP_002413125.1 2450405 D 585056 CDS YP_002413126.1 218705607 7158820 complement(2450931..2451692) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2451692 yegK 7158820 yegK Escherichia coli UMN026 hypothetical protein YP_002413126.1 2450931 R 585056 CDS YP_002413127.1 218705608 7158821 complement(2451689..2452348) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2452348 yegL 7158821 yegL Escherichia coli UMN026 hypothetical protein YP_002413127.1 2451689 R 585056 CDS YP_002413128.1 218705609 7157842 2453892..2455139 1 NC_011751.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2455139 mdtA 7157842 mdtA Escherichia coli UMN026 multidrug efflux system subunit MdtA YP_002413128.1 2453892 D 585056 CDS YP_002413129.1 218705610 7157077 2455139..2458261 1 NC_011751.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2458261 mdtB 7157077 mdtB Escherichia coli UMN026 multidrug efflux system subunit MdtB YP_002413129.1 2455139 D 585056 CDS YP_002413130.1 218705611 7157078 2458262..2461339 1 NC_011751.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2461339 mdtC 7157078 mdtC Escherichia coli UMN026 multidrug efflux system subunit MdtC YP_002413130.1 2458262 D 585056 CDS YP_002413131.1 218705612 7157079 2461340..2462755 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter; multidrug efflux system protein MdtE 2462755 mdtD 7157079 mdtD Escherichia coli UMN026 multidrug efflux system protein MdtE YP_002413131.1 2461340 D 585056 CDS YP_002413132.1 218705613 7157080 2462752..2464155 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; signal transduction histidine-protein kinase BaeS 2464155 baeS 7157080 baeS Escherichia coli UMN026 signal transduction histidine-protein kinase BaeS YP_002413132.1 2462752 D 585056 CDS YP_002413133.1 218705614 7155850 2464152..2464874 1 NC_011751.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2464874 baeR 7155850 baeR Escherichia coli UMN026 DNA-binding transcriptional regulator BaeR YP_002413133.1 2464152 D 585056 CDS YP_002413134.1 218705615 7155849 2465054..2465386 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2465386 yegP 7155849 yegP Escherichia coli UMN026 hypothetical protein YP_002413134.1 2465054 D 585056 CDS YP_002413135.1 218705616 7158823 2465534..2466895 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2466895 yegQ 7158823 yegQ Escherichia coli UMN026 putative peptidase YP_002413135.1 2465534 D 585056 CDS YP_002413136.1 218705617 7157843 complement(2467224..2467541) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2467541 yegR 7157843 yegR Escherichia coli UMN026 hypothetical protein YP_002413136.1 2467224 R 585056 CDS YP_002413137.1 218705618 7158825 2467956..2468855 1 NC_011751.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2468855 yegS 7158825 yegS Escherichia coli UMN026 lipid kinase YP_002413137.1 2467956 D 585056 CDS YP_002413138.1 218705619 7158826 complement(2468937..2469716) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7772602; Product type r : regulator; Galactitol utilization operon repressor 2469716 gatR 7158826 gatR Escherichia coli UMN026 Galactitol utilization operon repressor YP_002413138.1 2468937 R 585056 CDS YP_002413139.1 218705620 7156514 complement(2469816..2470856) 1 NC_011751.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase 2470856 gatD 7156514 gatD Escherichia coli UMN026 galactitol-1-phosphate dehydrogenase YP_002413139.1 2469816 R 585056 CDS YP_002413140.1 218705621 7156513 complement(2470904..2472259) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76024805, 77192083, 97113438, 7772602; Product type t : transporter; galactitol-specific enzyme IIC component of PTS 2472259 gatC 7156513 gatC Escherichia coli UMN026 galactitol-specific enzyme IIC component of PTS YP_002413140.1 2470904 R 585056 CDS YP_002413141.1 218705622 7156512 complement(2472263..2472547) 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB 2472547 gatB 7156512 gatB Escherichia coli UMN026 PTS system galactitol-specific transporter subunit IIB YP_002413141.1 2472263 R 585056 CDS YP_002413142.1 218705623 7156511 complement(2472578..2473030) 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA 2473030 gatA 7156511 gatA Escherichia coli UMN026 PTS system galactitol-specific transporter subunit IIA YP_002413142.1 2472578 R 585056 CDS YP_002413143.1 218705624 7156510 complement(2473040..2474302) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 97113438, 7772602, 8932697; Product type e : enzyme; D-tagatose 1,6-bisphosphate aldolase 2, subunit 2474302 gatZ 7156510 gatZ Escherichia coli UMN026 D-tagatose 1,6-bisphosphate aldolase 2, subunit YP_002413143.1 2473040 R 585056 CDS YP_002413144.1 218705625 7156516 complement(2474331..2475185) 1 NC_011751.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 2475185 gatY 7156516 gatY Escherichia coli UMN026 tagatose-bisphosphate aldolase YP_002413144.1 2474331 R 585056 CDS YP_002413145.1 218705626 7156515 complement(2475413..2476465) 1 NC_011751.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2476465 fbaB 7156515 fbaB Escherichia coli UMN026 fructose-bisphosphate aldolase YP_002413145.1 2475413 R 585056 CDS YP_002413146.1 218705627 7156310 2476722..2477999 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hydrophilic substrate MFS superfamily transporter 2477999 yegT 7156310 yegT Escherichia coli UMN026 putative hydrophilic substrate MFS superfamily transporter YP_002413146.1 2476722 D 585056 CDS YP_002413147.1 218705628 7158827 2477996..2479000 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative (phospho)hydrolase 2479000 yegU 7158827 yegU Escherichia coli UMN026 putative (phospho)hydrolase YP_002413147.1 2477996 D 585056 CDS YP_002413148.1 218705629 7158828 2478997..2479962 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative kinase 2479962 yegV 7158828 yegV Escherichia coli UMN026 putative kinase YP_002413148.1 2478997 D 585056 CDS YP_002413149.1 218705630 7158829 complement(2479936..2480682) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2480682 yegW 7158829 yegW Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413149.1 2479936 R 585056 CDS YP_002413150.1 218705631 7158830 complement(2480734..2481552) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-bound hydrolase 2481552 yegX 7158830 yegX Escherichia coli UMN026 putative membrane-bound hydrolase YP_002413150.1 2480734 R 585056 CDS YP_002413151.1 218705632 7158831 complement(2481617..2482417) 1 NC_011751.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2482417 thiD 7158831 thiD Escherichia coli UMN026 phosphomethylpyrimidine kinase YP_002413151.1 2481617 R 585056 CDS YP_002413152.1 218705633 7158053 complement(2482414..2483202) 1 NC_011751.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2483202 thiM 7158053 thiM Escherichia coli UMN026 hydroxyethylthiazole kinase YP_002413152.1 2482414 R 585056 CDS YP_002413153.1 218705634 7158060 complement(2483425..2483697) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2483697 yohL 7158060 yohL Escherichia coli UMN026 hypothetical protein YP_002413153.1 2483425 R 585056 CDS YP_002413154.1 218705635 7159563 2483818..2484642 1 NC_011751.1 membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2484642 rncA 7159563 rncA Escherichia coli UMN026 nickel/cobalt efflux protein RcnA YP_002413154.1 2483818 D 585056 CDS YP_002413155.1 218705636 7157709 2484681..2485199 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2485199 yohN 7157709 yohN Escherichia coli UMN026 hypothetical protein YP_002413155.1 2484681 D 585056 CDS YP_002413156.1 218705637 7159564 complement(2485281..2486315) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative exported fimbrial-like adhesin protein 2486315 yehA 7159564 yehA Escherichia coli UMN026 putative exported fimbrial-like adhesin protein YP_002413156.1 2485281 R 585056 CDS YP_002413157.1 218705638 7158832 complement(2486331..2488811) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2488811 yehB 7158832 yehB Escherichia coli UMN026 hypothetical protein YP_002413157.1 2486331 R 585056 CDS YP_002413158.1 218705639 7158833 complement(2488827..2489501) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative membrane-associated pilin chaperone 2489501 yehC 7158833 yehC Escherichia coli UMN026 putative membrane-associated pilin chaperone YP_002413158.1 2488827 R 585056 CDS YP_002413159.1 218705640 7158834 complement(2489582..2490124) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial-like adhesin protein 2490124 yehD 7158834 yehD Escherichia coli UMN026 putative fimbrial-like adhesin protein YP_002413159.1 2489582 R 585056 CDS YP_002413160.1 218705641 7158835 complement(2490419..2490700) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2490700 yehE 7158835 yehE Escherichia coli UMN026 hypothetical protein YP_002413160.1 2490419 R 585056 CDS YP_002413161.1 218705642 7158836 complement(2490963..2492072) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter; putative ATPase 2492072 mrp 7158836 mrp Escherichia coli UMN026 putative ATPase YP_002413161.1 2490963 R 585056 CDS YP_002413162.1 218705643 7157182 2492204..2494237 1 NC_011751.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2494237 metG 7157182 metG Escherichia coli UMN026 methionyl-tRNA synthetase YP_002413162.1 2492204 D 585056 CDS YP_002413163.1 218705644 7157105 2494378..2498175 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type ph : phenotype; molybdate metabolism protein 2498175 7157105 ECUMN_2447 Escherichia coli UMN026 molybdate metabolism protein YP_002413163.1 2494378 D 585056 CDS YP_002413164.1 218705645 7155139 2498188..2501949 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810, 12480890; Product type pr : putative regulator; putative molybdate metabolism regulator (molR-like) 2501949 7155139 ECUMN_2448 Escherichia coli UMN026 putative molybdate metabolism regulator (molR-like) YP_002413164.1 2498188 D 585056 CDS YP_002413165.1 218705646 7155140 2501959..2505591 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2505591 yehI 7155140 yehI Escherichia coli UMN026 hypothetical protein YP_002413165.1 2501959 D 585056 CDS YP_002413166.1 218705647 7158837 2505652..2505957 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2505957 yehK 7158837 yehK Escherichia coli UMN026 hypothetical protein YP_002413166.1 2505652 D 585056 CDS YP_002413167.1 218705648 7158838 2507141..2508229 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : putative factor; putative ABC superfamily protein 2508229 yehL 7158838 yehL Escherichia coli UMN026 putative ABC superfamily protein YP_002413167.1 2507141 D 585056 CDS YP_002413168.1 218705649 7158839 2508240..2510519 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2510519 yehM 7158839 yehM Escherichia coli UMN026 hypothetical protein YP_002413168.1 2508240 D 585056 CDS YP_002413169.1 218705650 7158840 2510512..2511648 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2511648 yehP 7158840 yehP Escherichia coli UMN026 hypothetical protein YP_002413169.1 2510512 D 585056 CDS YP_002413170.1 218705651 7158841 2511645..2513645 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2513645 yehQ 7158841 yehQ Escherichia coli UMN026 hypothetical protein YP_002413170.1 2511645 D 585056 CDS YP_002413171.1 218705652 7158842 2513770..2514231 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type lp : lipoprotein; hypothetical protein 2514231 yehR 7158842 yehR Escherichia coli UMN026 hypothetical protein YP_002413171.1 2513770 D 585056 CDS YP_002413172.1 218705653 7158843 complement(2514273..2514743) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2514743 yehS 7158843 yehS Escherichia coli UMN026 hypothetical protein YP_002413172.1 2514273 R 585056 CDS YP_002413173.1 218705654 7158844 complement(2514790..2515509) 1 NC_011751.1 unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT 2515509 yehT 7158844 yehT Escherichia coli UMN026 putative two-component response-regulatory protein YehT YP_002413173.1 2514790 R 585056 CDS YP_002413174.1 218705655 7158845 complement(2515506..2517191) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor; sensory kinase in two-component system with YehT 2517191 yehU 7158845 yehU Escherichia coli UMN026 sensory kinase in two-component system with YehT YP_002413174.1 2515506 R 585056 CDS YP_002413175.1 218705656 7158846 2517413..2518144 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator; DNA-binding transcriptional regulator 2518144 mlrA 7158846 mlrA Escherichia coli UMN026 DNA-binding transcriptional regulator YP_002413175.1 2517413 D 585056 CDS YP_002413176.1 218705657 7157138 complement(2518292..2519023) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease 2519023 yehW 7157138 yehW Escherichia coli UMN026 putative ABC transporter permease YP_002413176.1 2518292 R 585056 CDS YP_002413177.1 218705658 7158847 complement(2519028..2519954) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 2519954 yehX 7158847 yehX Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002413177.1 2519028 R 585056 CDS YP_002413178.1 218705659 7158848 complement(2519947..2521104) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter permease 2521104 yehY 7158848 yehY Escherichia coli UMN026 putative ABC transporter permease YP_002413178.1 2519947 R 585056 CDS YP_002413179.1 218705660 7158849 complement(2521111..2522028) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : putative transporter; putative ABC transporter periplasmic-binding protein 2522028 yehZ 7158849 yehZ Escherichia coli UMN026 putative ABC transporter periplasmic-binding protein YP_002413179.1 2521111 R 585056 CDS YP_002413180.1 218705661 7158850 complement(2522177..2524474) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme; beta-D-glucoside glucohydrolase, periplasmic 2524474 bglX 7158850 bglX Escherichia coli UMN026 beta-D-glucoside glucohydrolase, periplasmic YP_002413180.1 2522177 R 585056 CDS YP_002413181.1 218705662 7155875 2524670..2526385 1 NC_011751.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2526385 dld 7155875 dld Escherichia coli UMN026 D-lactate dehydrogenase YP_002413181.1 2524670 D 585056 CDS YP_002413182.1 218705663 7156178 complement(2526423..2527355) 1 NC_011751.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2527355 pbpG 7156178 pbpG Escherichia coli UMN026 D-alanyl-D-alanine endopeptidase YP_002413182.1 2526423 R 585056 CDS YP_002413183.1 218705664 7157395 complement(2527529..2528116) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2528116 yohC 7157395 yohC Escherichia coli UMN026 hypothetical protein YP_002413183.1 2527529 R 585056 CDS YP_002413184.1 218705665 7159557 2528286..2528864 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2528864 yohD 7159557 yohD Escherichia coli UMN026 hypothetical protein YP_002413184.1 2528286 D 585056 CDS YP_002413185.1 218705666 7159558 complement(2528983..2529744) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; acetoin dehydrogenase 2529744 yohF 7159558 yohF Escherichia coli UMN026 acetoin dehydrogenase YP_002413185.1 2528983 R 585056 CDS YP_002413186.1 218705667 7159559 complement(2529797..2530885) 1 NC_011751.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ 2530885 yohG 7159559 yohG Escherichia coli UMN026 multidrug resistance outer membrane protein MdtQ YP_002413186.1 2529797 R 585056 CDS YP_002413187.1 218705668 7159560 complement(2531913..2532860) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA -dihydrouridine synthase C 2532860 dusC 7159560 dusC Escherichia coli UMN026 tRNA -dihydrouridine synthase C YP_002413187.1 2531913 R 585056 CDS YP_002413188.1 218705669 7156213 2533099..2533497 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2533497 yohJ 7156213 yohJ Escherichia coli UMN026 hypothetical protein YP_002413188.1 2533099 D 585056 CDS YP_002413189.1 218705670 7159561 2533494..2534189 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2534189 yohK 7159561 yohK Escherichia coli UMN026 hypothetical protein YP_002413189.1 2533494 D 585056 CDS YP_002413190.1 218705671 7159562 2534319..2535203 1 NC_011751.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2535203 cdd 7159562 cdd Escherichia coli UMN026 cytidine deaminase YP_002413190.1 2534319 D 585056 CDS YP_002413191.1 218705672 7155937 2535353..2536072 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448; hypothetical protein 2536072 sanA 7155937 sanA Escherichia coli UMN026 hypothetical protein YP_002413191.1 2535353 D 585056 CDS YP_002413192.1 218705673 7157864 2536075..2536314 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2536314 yeiS 7157864 yeiS Escherichia coli UMN026 hypothetical protein YP_002413192.1 2536075 D 585056 CDS YP_002413193.1 218705674 7158863 2536633..2537871 1 NC_011751.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2537871 yeiT 7158863 yeiT Escherichia coli UMN026 putative oxidoreductase YP_002413193.1 2536633 D 585056 CDS YP_002413194.1 218705675 7158864 2537865..2539100 1 NC_011751.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2539100 yeiA 7158864 yeiA Escherichia coli UMN026 dihydropyrimidine dehydrogenase YP_002413194.1 2537865 D 585056 CDS YP_002413195.1 218705676 7158851 complement(2539171..2540181) 1 NC_011751.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 2540181 mglC 7158851 mglC Escherichia coli UMN026 beta-methylgalactoside transporter inner membrane component YP_002413195.1 2539171 R 585056 CDS YP_002413196.1 218705677 7157117 complement(2540197..2541717) 1 NC_011751.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2541717 mglA 7157117 mglA Escherichia coli UMN026 galactose/methyl galaxtoside transporter ATP-binding protein YP_002413196.1 2540197 R 585056 CDS YP_002413197.1 218705678 7157115 complement(2541778..2542776) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter; methyl-galactoside ABC transporter periplasmic-binding protein 2542776 mglB 7157115 mglB Escherichia coli UMN026 methyl-galactoside ABC transporter periplasmic-binding protein YP_002413197.1 2541778 R 585056 CDS YP_002413198.1 218705679 7157116 complement(2543056..2544096) 1 NC_011751.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2544096 galS 7157116 galS Escherichia coli UMN026 DNA-binding transcriptional regulator GalS YP_002413198.1 2543056 R 585056 CDS YP_002413199.1 218705680 7156499 2544086..2544289 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2544289 7156499 ECUMN_2485 Escherichia coli UMN026 hypothetical protein YP_002413199.1 2544086 D 585056 CDS YP_002413200.1 218705681 7155141 complement(2544238..2545395) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2545395 yeiB 7155141 yeiB Escherichia coli UMN026 hypothetical protein YP_002413200.1 2544238 R 585056 CDS YP_002413201.1 218705682 7158852 complement(2545412..2546080) 1 NC_011751.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2546080 folE 7158852 folE Escherichia coli UMN026 GTP cyclohydrolase I YP_002413201.1 2545412 R 585056 CDS YP_002413202.1 218705683 7156427 2546234..2546410 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2546410 7156427 ECUMN_2488 Escherichia coli UMN026 hypothetical protein YP_002413202.1 2546234 D 585056 CDS YP_002413203.1 218705684 7155142 2546338..2547174 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme; S-formylglutathione hydrolase 2547174 frmC 7155142 frmC Escherichia coli UMN026 S-formylglutathione hydrolase YP_002413203.1 2546338 D 585056 CDS YP_002413204.1 218705685 7156441 complement(2547206..2549185) 1 NC_011751.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2549185 cirA 7156441 cirA Escherichia coli UMN026 colicin I receptor YP_002413204.1 2547206 R 585056 CDS YP_002413205.1 218705686 7155965 complement(2549178..2549381) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2549381 7155965 ECUMN_2491 Escherichia coli UMN026 hypothetical protein YP_002413205.1 2549178 R 585056 CDS YP_002413206.1 218705687 7155143 complement(2549478..2550947) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter; lysine transporter 2550947 lysP 7155143 lysP Escherichia coli UMN026 lysine transporter YP_002413206.1 2549478 R 585056 CDS YP_002413207.1 218705688 7157031 complement(2551152..2552033) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2552033 yeiE 7157031 yeiE Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413207.1 2551152 R 585056 CDS YP_002413208.1 218705689 7158854 2552132..2553181 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2553181 yeiH 7158854 yeiH Escherichia coli UMN026 hypothetical protein YP_002413208.1 2552132 D 585056 CDS YP_002413209.1 218705690 7158855 2553255..2554112 1 NC_011751.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2554112 nfo 7158855 nfo Escherichia coli UMN026 endonuclease IV YP_002413209.1 2553255 D 585056 CDS YP_002413210.1 218705691 7157267 2554115..2555203 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2555203 yeiI 7157267 yeiI Escherichia coli UMN026 hypothetical protein YP_002413210.1 2554115 D 585056 CDS YP_002413211.1 218705692 7158856 complement(2555310..2556560) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/proton nucleoside transporter 2556560 yeiJ 7158856 yeiJ Escherichia coli UMN026 putative sodium/proton nucleoside transporter YP_002413211.1 2555310 R 585056 CDS YP_002413212.1 218705693 7158857 complement(2556660..2557601) 1 NC_011751.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2557601 rihB 7158857 rihB Escherichia coli UMN026 ribonucleoside hydrolase 2 YP_002413212.1 2556660 R 585056 CDS YP_002413213.1 218705694 7157689 2557770..2558429 1 NC_011751.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2558429 yeiL 7157689 yeiL Escherichia coli UMN026 DNA-binding transcriptional activator YeiL YP_002413213.1 2557770 D 585056 CDS YP_002413214.1 218705695 7158858 complement(2558497..2559747) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sodium/proton nucleoside transporter 2559747 yeiM 7158858 yeiM Escherichia coli UMN026 putative sodium/proton nucleoside transporter YP_002413214.1 2558497 R 585056 CDS YP_002413215.1 218705696 7158859 complement(2559841..2560779) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2560779 yeiN 7158859 yeiN Escherichia coli UMN026 hypothetical protein YP_002413215.1 2559841 R 585056 CDS YP_002413216.1 218705697 7158860 complement(2560767..2561708) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2561708 yeiC 7158860 yeiC Escherichia coli UMN026 hypothetical protein YP_002413216.1 2560767 R 585056 CDS YP_002413217.1 218705698 7158853 complement(2562132..2563823) 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 2563823 fruA 7158853 fruA Escherichia coli UMN026 PTS system fructose-specific transporter subunits IIBC YP_002413217.1 2562132 R 585056 CDS YP_002413218.1 218705699 7156445 complement(2563840..2564778) 1 NC_011751.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2564778 fruK 7156445 fruK Escherichia coli UMN026 1-phosphofructokinase YP_002413218.1 2563840 R 585056 CDS YP_002413219.1 218705700 7156447 complement(2564778..2565908) 1 NC_011751.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 2565908 fruB 7156447 fruB Escherichia coli UMN026 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_002413219.1 2564778 R 585056 CDS YP_002413220.1 218705701 7156446 2566276..2567457 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; lactose/glucose efflux system 2567457 setB 7156446 setB Escherichia coli UMN026 lactose/glucose efflux system YP_002413220.1 2566276 D 585056 CDS YP_002413221.1 218705702 7157901 complement(2567454..2567840) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2567840 7157901 ECUMN_2507 Escherichia coli UMN026 hypothetical protein YP_002413221.1 2567454 R 585056 CDS YP_002413222.1 218705703 7155144 2567608..2568435 1 NC_011751.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2568435 7155144 ECUMN_2508 Escherichia coli UMN026 elongation factor P YP_002413222.1 2567608 D 585056 CDS YP_002413223.1 218705704 7155145 2568658..2570124 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar dehydrogenase 2570124 yeiQ 7155145 yeiQ Escherichia coli UMN026 putative sugar dehydrogenase YP_002413223.1 2568658 D 585056 CDS YP_002413224.1 218705705 7158861 2570242..2571228 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2571228 yeiR 7158861 yeiR Escherichia coli UMN026 hypothetical protein YP_002413224.1 2570242 D 585056 CDS YP_002413225.1 218705706 7158862 2571267..2571980 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 2571980 yeiU 7158862 yeiU Escherichia coli UMN026 undecaprenyl pyrophosphate phosphatase YP_002413225.1 2571267 D 585056 CDS YP_002413226.1 218705707 7158865 2572392..2572958 1 NC_011751.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2572958 spr 7158865 spr Escherichia coli UMN026 putative outer membrane lipoprotein YP_002413226.1 2572392 D 585056 CDS YP_002413227.1 218705708 7157966 2573139..2574695 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2574695 rtn 7157966 rtn Escherichia coli UMN026 hypothetical protein YP_002413227.1 2573139 D 585056 CDS YP_002413228.1 218705709 7157815 2574777..2576591 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter periplasmic-binding protein 2576591 yejA 7157815 yejA Escherichia coli UMN026 putative oligopeptide ABC transporter periplasmic-binding protein YP_002413228.1 2574777 D 585056 CDS YP_002413229.1 218705710 7158866 2576592..2577686 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter permease 2577686 yejB 7158866 yejB Escherichia coli UMN026 putative oligopeptide ABC transporter permease YP_002413229.1 2576592 D 585056 CDS YP_002413230.1 218705711 7158867 2577686..2578711 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter permease 2578711 yejE 7158867 yejE Escherichia coli UMN026 putative oligopeptide ABC transporter permease YP_002413230.1 2577686 D 585056 CDS YP_002413231.1 218705712 7158868 2578713..2580302 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative oligopeptide ABC transporter ATP-binding protein 2580302 yejF 7158868 yejF Escherichia coli UMN026 putative oligopeptide ABC transporter ATP-binding protein YP_002413231.1 2578713 D 585056 CDS YP_002413232.1 218705713 7158869 complement(2580306..2580650) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2580650 yejG 7158869 yejG Escherichia coli UMN026 hypothetical protein YP_002413232.1 2580306 R 585056 CDS YP_002413233.1 218705714 7158870 complement(2580983..2582173) 1 NC_011751.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 2582173 bcr 7158870 bcr Escherichia coli UMN026 bicyclomycin/multidrug efflux system YP_002413233.1 2580983 R 585056 CDS YP_002413234.1 218705715 7155856 complement(2582201..2582896) 1 NC_011751.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2582896 rsuA 7155856 rsuA Escherichia coli UMN026 16S rRNA pseudouridylate synthase A YP_002413234.1 2582201 R 585056 CDS YP_002413235.1 218705716 7157805 2583046..2584806 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleic acid ATP-dependent helicase 2584806 yejH 7157805 yejH Escherichia coli UMN026 putative nucleic acid ATP-dependent helicase YP_002413235.1 2583046 D 585056 CDS YP_002413236.1 218705717 7158871 2584931..2585215 1 NC_011751.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2585215 rplY 7158871 rplY Escherichia coli UMN026 50S ribosomal protein L25 YP_002413236.1 2584931 D 585056 CDS YP_002413237.1 218705718 7157747 complement(2585354..2586361) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor; nucleoid-associated protein NdpA 2586361 yejK 7157747 yejK Escherichia coli UMN026 nucleoid-associated protein NdpA YP_002413237.1 2585354 R 585056 CDS YP_002413238.1 218705719 7158872 2586543..2586770 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2586770 yejL 7158872 yejL Escherichia coli UMN026 hypothetical protein YP_002413238.1 2586543 D 585056 CDS YP_002413239.1 218705720 7158873 2586790..2588550 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 2588550 yejM 7158873 yejM Escherichia coli UMN026 putative hydrolase YP_002413239.1 2586790 D 585056 CDS YP_002413240.1 218705721 7155577 complement(2588804..2591314) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pt : putative transporter; putative autotransporter outer membrane protein; type V secretion 2591314 yejO 7155577 yejO Escherichia coli UMN026 putative autotransporter outer membrane protein; type V secretion YP_002413240.1 2588804 R 585056 CDS YP_002413241.1 218705722 7158875 2591715..2592362 1 NC_011751.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2592362 narP 7158875 narP Escherichia coli UMN026 transcriptional regulator NarP YP_002413241.1 2591715 D 585056 CDS YP_002413242.1 218705723 7157253 complement(2592397..2593449) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : putative enzyme; heme lyase, CcmH subunit 2593449 ccmH 7157253 ccmH Escherichia coli UMN026 heme lyase, CcmH subunit YP_002413242.1 2592397 R 585056 CDS YP_002413243.1 218705724 7155935 complement(2593446..2594003) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme; periplasmic thioredoxin of cytochrome c-type biogenesis 2594003 ccmG 7155935 ccmG Escherichia coli UMN026 periplasmic thioredoxin of cytochrome c-type biogenesis YP_002413243.1 2593446 R 585056 CDS YP_002413244.1 218705725 7155934 complement(2594000..2595943) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme; heme lyase, CcmF subunit 2595943 ccmF 7155934 ccmF Escherichia coli UMN026 heme lyase, CcmF subunit YP_002413244.1 2594000 R 585056 CDS YP_002413245.1 218705726 7155933 complement(2595940..2596419) 1 NC_011751.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2596419 ccmE 7155933 ccmE Escherichia coli UMN026 cytochrome c-type biogenesis protein CcmE YP_002413245.1 2595940 R 585056 CDS YP_002413246.1 218705727 7155932 complement(2596416..2596625) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor; cytochrome c biogenesis protein 2596625 ccmD 7155932 ccmD Escherichia coli UMN026 cytochrome c biogenesis protein YP_002413246.1 2596416 R 585056 CDS YP_002413247.1 218705728 7155931 complement(2596622..2597359) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter; heme exporter membrane protein 2597359 ccmC 7155931 ccmC Escherichia coli UMN026 heme exporter membrane protein YP_002413247.1 2596622 R 585056 CDS YP_002413248.1 218705729 7155930 complement(2597401..2598063) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter; heme exporter membrane protein 2598063 ccmB 7155930 ccmB Escherichia coli UMN026 heme exporter membrane protein YP_002413248.1 2597401 R 585056 CDS YP_002413249.1 218705730 7155929 complement(2598060..2598683) 1 NC_011751.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2598683 ccmA 7155929 ccmA Escherichia coli UMN026 cytochrome c biogenesis protein CcmA YP_002413249.1 2598060 R 585056 CDS YP_002413250.1 218705731 7155928 complement(2598696..2599298) 1 NC_011751.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2599298 napC 7155928 napC Escherichia coli UMN026 cytochrome c-type protein NapC YP_002413250.1 2598696 R 585056 CDS YP_002413251.1 218705732 7157242 complement(2599308..2599757) 1 NC_011751.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2599757 napB 7157242 napB Escherichia coli UMN026 citrate reductase cytochrome c-type subunit YP_002413251.1 2599308 R 585056 CDS YP_002413252.1 218705733 7157241 complement(2599754..2600617) 1 NC_011751.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2600617 napH 7157241 napH Escherichia coli UMN026 quinol dehydrogenase membrane component YP_002413252.1 2599754 R 585056 CDS YP_002413253.1 218705734 7157246 complement(2600604..2601299) 1 NC_011751.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2601299 napG 7157246 napG Escherichia coli UMN026 quinol dehydrogenase periplasmic component YP_002413253.1 2600604 R 585056 CDS YP_002413254.1 218705735 7157245 complement(2601306..2603792) 1 NC_011751.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2603792 napA 7157245 napA Escherichia coli UMN026 nitrate reductase catalytic subunit YP_002413254.1 2601306 R 585056 CDS YP_002413255.1 218705736 7157240 complement(2603789..2604052) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor; assembly protein for periplasmic nitrate reductase 2604052 napD 7157240 napD Escherichia coli UMN026 assembly protein for periplasmic nitrate reductase YP_002413255.1 2603789 R 585056 CDS YP_002413256.1 218705737 7157243 complement(2604042..2604536) 1 NC_011751.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2604536 napF 7157243 napF Escherichia coli UMN026 ferredoxin-type protein YP_002413256.1 2604042 R 585056 CDS YP_002413257.1 218705738 7157244 2604636..2604809 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2604809 7157244 ECUMN_2544 Escherichia coli UMN026 hypothetical protein YP_002413257.1 2604636 D 585056 CDS YP_002413258.1 218705739 7155146 2604944..2605432 1 NC_011751.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2605432 eco 7155146 eco Escherichia coli UMN026 ecotin YP_002413258.1 2604944 D 585056 CDS YP_002413259.1 218705740 7156224 complement(2605580..2607226) 1 NC_011751.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2607226 mqo 7156224 mqo Escherichia coli UMN026 malate:quinone oxidoreductase YP_002413259.1 2605580 R 585056 CDS YP_002413260.1 218705741 7157170 complement(2607444..2609087) 1 NC_011751.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding component 2609087 yojI 7157170 yojI Escherichia coli UMN026 multidrug transporter membrane component/ATP-binding component YP_002413260.1 2607444 R 585056 CDS YP_002413261.1 218705742 7159565 complement(2609163..2609813) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme; oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions 2609813 alkB 7159565 alkB Escherichia coli UMN026 oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions YP_002413261.1 2609163 R 585056 CDS YP_002413262.1 218705743 7155725 complement(2609813..2610877) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 2610877 ada 7155725 ada Escherichia coli UMN026 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase YP_002413262.1 2609813 R 585056 CDS YP_002413263.1 218705744 7155695 complement(2610951..2612006) 1 NC_011751.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 2612006 yojL 7155695 yojL Escherichia coli UMN026 thiamine biosynthesis lipoprotein ApbE YP_002413263.1 2610951 R 585056 CDS YP_002413264.1 218705745 7159566 complement(2612118..2613221) 1 NC_011751.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 2613221 ompC 7159566 ompC Escherichia coli UMN026 outer membrane porin protein C YP_002413264.1 2612118 R 585056 CDS YP_002413265.1 218705746 7157132 2613960..2616632 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2616632 rcsD 7157132 rcsD Escherichia coli UMN026 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_002413265.1 2613960 D 585056 CDS YP_002413266.1 218705747 7157631 2616649..2617299 1 NC_011751.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2617299 rcsB 7157631 rcsB Escherichia coli UMN026 transcriptional regulator RcsB YP_002413266.1 2616649 D 585056 CDS YP_002413267.1 218705748 7157629 complement(2617499..2620300) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 2620300 rcsC 7157629 rcsC Escherichia coli UMN026 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002413267.1 2617499 R 585056 CDS YP_002413268.1 218705749 7157630 2620418..2620621 1 NC_011751.1 hypothetical protein 2620621 7157630 ECUMN_2556 Escherichia coli UMN026 hypothetical protein YP_002413268.1 2620418 D 585056 CDS YP_002413269.1 218705750 7155147 2620515..2622341 1 NC_011751.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2622341 atoS 7155147 atoS Escherichia coli UMN026 sensory histidine kinase AtoS YP_002413269.1 2620515 D 585056 CDS YP_002413270.1 218705751 7155832 2622338..2623723 1 NC_011751.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2623723 atoC 7155832 atoC Escherichia coli UMN026 acetoacetate metabolism regulatory protein AtoC YP_002413270.1 2622338 D 585056 CDS YP_002413271.1 218705752 7155829 2623919..2624581 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2624581 atoD 7155829 atoD Escherichia coli UMN026 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_002413271.1 2623919 D 585056 CDS YP_002413272.1 218705753 7155830 2624581..2625231 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit beta 2625231 atoA 7155830 atoA Escherichia coli UMN026 acetyl-CoA:acetoacetyl-CoA transferase subunit beta YP_002413272.1 2624581 D 585056 CDS YP_002413273.1 218705754 7155827 2625228..2626550 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter; short chain fatty acid transporter 2626550 atoE 7155827 atoE Escherichia coli UMN026 short chain fatty acid transporter YP_002413273.1 2625228 D 585056 CDS YP_002413274.1 218705755 7155831 2626581..2627765 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA acetyltransferase 2627765 atoB 7155831 atoB Escherichia coli UMN026 acetyl-CoA acetyltransferase YP_002413274.1 2626581 D 585056 CDS YP_002413275.1 218705756 7155828 complement(2627839..2628615) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2628615 yfaP 7155828 yfaP Escherichia coli UMN026 hypothetical protein YP_002413275.1 2627839 R 585056 CDS YP_002413276.1 218705757 7158881 complement(2628620..2630269) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2630269 yfaQ 7158881 yfaQ Escherichia coli UMN026 hypothetical protein YP_002413276.1 2628620 R 585056 CDS YP_002413277.1 218705758 7158882 complement(2630270..2634889) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative large extracellular alpha-helical protein 2634889 7158882 ECUMN_2565 Escherichia coli UMN026 putative large extracellular alpha-helical protein YP_002413277.1 2630270 R 585056 CDS YP_002413278.1 218705759 7155148 complement(2634808..2635431) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2635431 yfaT 7155148 yfaT Escherichia coli UMN026 hypothetical protein YP_002413278.1 2634808 R 585056 CDS YP_002413279.1 218705760 7158883 complement(2635428..2637116) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2637116 yfaA 7158883 yfaA Escherichia coli UMN026 hypothetical protein YP_002413279.1 2635428 R 585056 CDS YP_002413280.1 218705761 7158876 complement(2637265..2639892) 1 NC_011751.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 2639892 gyrA 7158876 gyrA Escherichia coli UMN026 DNA gyrase subunit A YP_002413280.1 2637265 R 585056 CDS YP_002413281.1 218705762 7156631 2640039..2640761 1 NC_011751.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2640761 ubiG 7156631 ubiG Escherichia coli UMN026 3-demethylubiquinone-9 3-methyltransferase YP_002413281.1 2640039 D 585056 CDS YP_002413282.1 218705763 7158158 complement(2640822..2644535) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor; adhesin 2644535 yfaL 7158158 yfaL Escherichia coli UMN026 adhesin YP_002413282.1 2640822 R 585056 CDS YP_002413283.1 218705764 7158879 2645231..2647516 1 NC_011751.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2647516 nrdA 7158879 nrdA Escherichia coli UMN026 ribonucleotide-diphosphate reductase subunit alpha YP_002413283.1 2645231 D 585056 CDS YP_002413284.1 218705765 7157298 2647750..2648880 1 NC_011751.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2648880 nrdB 7157298 nrdB Escherichia coli UMN026 ribonucleotide-diphosphate reductase subunit beta YP_002413284.1 2647750 D 585056 CDS YP_002413285.1 218705766 7157299 2648880..2649134 1 NC_011751.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin YfaE 2649134 yfaE 7157299 yfaE Escherichia coli UMN026 2Fe-2S ferredoxin YfaE YP_002413285.1 2648880 D 585056 CDS YP_002413286.1 218705767 7158878 complement(2649188..2649838) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316; hypothetical protein 2649838 inaA 7158878 inaA Escherichia coli UMN026 hypothetical protein YP_002413286.1 2649188 R 585056 CDS YP_002413287.1 218705768 7156810 complement(2649919..2651109) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11206551, 11258796; Product type pt : putative transporter; putative antibiotic efflux protein 2651109 7156810 ECUMN_2575 Escherichia coli UMN026 putative antibiotic efflux protein YP_002413287.1 2649919 R 585056 CDS YP_002413288.1 218705769 7155149 2651261..2652139 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 2652139 7155149 ECUMN_2576 Escherichia coli UMN026 putative transcriptional regulator YP_002413288.1 2651261 D 585056 CDS YP_002413289.1 218705770 7155150 2652569..2653675 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2653675 7155150 ECUMN_2578 Escherichia coli UMN026 hypothetical protein YP_002413289.1 2652569 D 585056 CDS YP_002413290.1 218705771 7155151 complement(2653896..2654972) 1 NC_011751.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 2654972 glpQ 7155151 glpQ Escherichia coli UMN026 glycerophosphodiester phosphodiesterase YP_002413290.1 2653896 R 585056 CDS YP_002413291.1 218705772 7156569 complement(2654977..2656335) 1 NC_011751.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 2656335 glpT 7156569 glpT Escherichia coli UMN026 sn-glycerol-3-phosphate transporter YP_002413291.1 2654977 R 585056 CDS YP_002413292.1 218705773 7156571 2656608..2658236 1 NC_011751.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2658236 glpA 7156571 glpA Escherichia coli UMN026 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002413292.1 2656608 D 585056 CDS YP_002413293.1 218705774 7156561 2658226..2659485 1 NC_011751.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2659485 glpB 7156561 glpB Escherichia coli UMN026 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002413293.1 2658226 D 585056 CDS YP_002413294.1 218705775 7156562 2659482..2660672 1 NC_011751.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2660672 glpC 7156562 glpC Escherichia coli UMN026 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002413294.1 2659482 D 585056 CDS YP_002413295.1 218705776 7156563 2660865..2661824 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2661824 yfaD 7156563 yfaD Escherichia coli UMN026 hypothetical protein YP_002413295.1 2660865 D 585056 CDS YP_002413296.1 218705777 7158877 2661837..2662034 1 NC_011751.1 Evidence 7 : Gene remnant; hypothetical protein 2662034 ypaA 7158877 ypaA Escherichia coli UMN026 hypothetical protein YP_002413296.1 2661837 D 585056 CDS YP_002413297.1 218705778 7159567 complement(2662075..2662878) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12454498, 16511168, 8550403; Product type pe : putative enzyme; putative aldolase 2662878 yfaU 7159567 yfaU Escherichia coli UMN026 putative aldolase YP_002413297.1 2662075 R 585056 CDS YP_002413298.1 218705779 7158884 complement(2662895..2664136) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative carboxylate transporter; phthalate permease family 2664136 yfaV 7158884 yfaV Escherichia coli UMN026 putative carboxylate transporter; phthalate permease family YP_002413298.1 2662895 R 585056 CDS YP_002413299.1 218705780 7158885 complement(2664166..2665374) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase 2665374 ydcM 7158885 ydcM Escherichia coli UMN026 putative transposase YP_002413299.1 2664166 R 585056 CDS YP_002413300.1 218705781 7158610 complement(2665352..2665498) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2665498 7158610 ECUMN_2589 Escherichia coli UMN026 hypothetical protein YP_002413300.1 2665352 R 585056 CDS YP_002413301.1 218705782 7155152 complement(2665857..2667065) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 2667065 yfaY 7155152 yfaY Escherichia coli UMN026 competence damage-inducible protein A YP_002413301.1 2665857 R 585056 CDS YP_002413302.1 218705783 7158886 complement(2667165..2667707) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane porin protein 2667707 yfaZ 7158886 yfaZ Escherichia coli UMN026 putative outer membrane porin protein YP_002413302.1 2667165 R 585056 CDS YP_002413303.1 218705784 7158887 2667986..2668411 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme; putative NUDIX hydrolase 2668411 yfaO 7158887 yfaO Escherichia coli UMN026 putative NUDIX hydrolase YP_002413303.1 2667986 D 585056 CDS YP_002413304.1 218705785 7158880 complement(2668450..2669052) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2669052 ais 7158880 ais Escherichia coli UMN026 hypothetical protein YP_002413304.1 2668450 R 585056 CDS YP_002413305.1 218705786 7155720 2669342..2670499 1 NC_011751.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2670499 yfbE 7155720 yfbE Escherichia coli UMN026 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_002413305.1 2669342 D 585056 CDS YP_002413306.1 218705787 7158889 2670503..2671471 1 NC_011751.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2671471 yfbF 7158889 yfbF Escherichia coli UMN026 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002413306.1 2670503 D 585056 CDS YP_002413307.1 218705788 7158890 2671471..2673453 1 NC_011751.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2673453 yfbG 7158890 yfbG Escherichia coli UMN026 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_002413307.1 2671471 D 585056 CDS YP_002413308.1 218705789 7158891 2673450..2674340 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2674340 yfbH 7158891 yfbH Escherichia coli UMN026 hypothetical protein YP_002413308.1 2673450 D 585056 CDS YP_002413309.1 218705790 7158892 2674340..2675992 1 NC_011751.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2675992 arnT 7158892 arnT Escherichia coli UMN026 4-amino-4-deoxy-L-arabinose transferase YP_002413309.1 2674340 D 585056 CDS YP_002413310.1 218705791 7155782 2675989..2676324 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2676324 yfbW 7155782 yfbW Escherichia coli UMN026 hypothetical protein YP_002413310.1 2675989 D 585056 CDS YP_002413311.1 218705792 7158902 2676042..2676710 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2676710 yfbJ 7158902 yfbJ Escherichia coli UMN026 hypothetical protein YP_002413311.1 2676042 D 585056 CDS YP_002413312.1 218705793 7158893 complement(2676704..2676970) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : putative transporter; polymyxin resistance protein B 2676970 pmrD 7158893 pmrD Escherichia coli UMN026 polymyxin resistance protein B YP_002413312.1 2676704 R 585056 CDS YP_002413313.1 218705794 7157477 complement(2677080..2678435) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme; O-succinylbenzoic acid--CoA ligase 2678435 menE 7157477 menE Escherichia coli UMN026 O-succinylbenzoic acid--CoA ligase YP_002413313.1 2677080 R 585056 CDS YP_002413314.1 218705795 7157097 complement(2678432..2679394) 1 NC_011751.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2679394 menC 7157097 menC Escherichia coli UMN026 O-succinylbenzoate synthase YP_002413314.1 2678432 R 585056 CDS YP_002413315.1 218705796 7157095 complement(2679394..2680251) 1 NC_011751.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2680251 menB 7157095 menB Escherichia coli UMN026 naphthoate synthase YP_002413315.1 2679394 R 585056 CDS YP_002413316.1 218705797 7157094 complement(2680266..2681024) 1 NC_011751.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 2681024 yfbB 7157094 yfbB Escherichia coli UMN026 acyl-CoA thioester hydrolase YfbB YP_002413316.1 2680266 R 585056 CDS YP_002413317.1 218705798 7158888 complement(2681021..2682691) 1 NC_011751.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2682691 menD 7158888 menD Escherichia coli UMN026 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002413317.1 2681021 R 585056 CDS YP_002413318.1 218705799 7157096 complement(2682780..2684075) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme; isochorismate synthase 2 2684075 menF 7157096 menF Escherichia coli UMN026 isochorismate synthase 2 YP_002413318.1 2682780 R 585056 CDS YP_002413319.1 218705800 7157098 complement(2684154..2684459) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2684459 elaB 7157098 elaB Escherichia coli UMN026 hypothetical protein YP_002413319.1 2684154 R 585056 CDS YP_002413320.1 218705801 7156235 complement(2684514..2684975) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2684975 elaA 7156235 elaA Escherichia coli UMN026 hypothetical protein YP_002413320.1 2684514 R 585056 CDS YP_002413321.1 218705802 7156234 2685040..2685957 1 NC_011751.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2685957 elaC 7156234 elaC Escherichia coli UMN026 ribonuclease Z YP_002413321.1 2685040 D 585056 CDS YP_002413322.1 218705803 7156236 2686148..2687356 1 NC_011751.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2687356 elaD 7156236 elaD Escherichia coli UMN026 deubiquitinase YP_002413322.1 2686148 D 585056 CDS YP_002413323.1 218705804 7156237 2687746..2688717 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane-associated peptidase 2688717 yfbL 7156237 yfbL Escherichia coli UMN026 putative membrane-associated peptidase YP_002413323.1 2687746 D 585056 CDS YP_002413324.1 218705805 7158894 2688820..2689323 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2689323 yfbM 7158894 yfbM Escherichia coli UMN026 hypothetical protein YP_002413324.1 2688820 D 585056 CDS YP_002413325.1 218705806 7158895 complement(2689391..2690668) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2690668 nuoN 7158895 nuoN Escherichia coli UMN026 NADH dehydrogenase subunit N YP_002413325.1 2689391 R 585056 CDS YP_002413326.1 218705807 7157335 complement(2690855..2692384) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2692384 nuoM 7157335 nuoM Escherichia coli UMN026 NADH dehydrogenase subunit M YP_002413326.1 2690855 R 585056 CDS YP_002413327.1 218705808 7157334 complement(2692548..2694389) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2694389 nuoL 7157334 nuoL Escherichia coli UMN026 NADH dehydrogenase subunit L YP_002413327.1 2692548 R 585056 CDS YP_002413328.1 218705809 7157333 complement(2694386..2694688) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2694688 nuoK 7157333 nuoK Escherichia coli UMN026 NADH dehydrogenase subunit K YP_002413328.1 2694386 R 585056 CDS YP_002413329.1 218705810 7157332 complement(2694685..2695239) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2695239 nuoJ 7157332 nuoJ Escherichia coli UMN026 NADH dehydrogenase subunit J YP_002413329.1 2694685 R 585056 CDS YP_002413330.1 218705811 7157331 complement(2695251..2695793) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2695793 nuoI 7157331 nuoI Escherichia coli UMN026 NADH dehydrogenase subunit I YP_002413330.1 2695251 R 585056 CDS YP_002413331.1 218705812 7157330 complement(2695808..2696785) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2696785 nuoH 7157330 nuoH Escherichia coli UMN026 NADH dehydrogenase subunit H YP_002413331.1 2695808 R 585056 CDS YP_002413332.1 218705813 7157329 complement(2696782..2699514) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2699514 nuoG 7157329 nuoG Escherichia coli UMN026 NADH dehydrogenase subunit G YP_002413332.1 2696782 R 585056 CDS YP_002413333.1 218705814 7157328 complement(2699561..2700898) 1 NC_011751.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2700898 nuoF 7157328 nuoF Escherichia coli UMN026 NADH dehydrogenase I subunit F YP_002413333.1 2699561 R 585056 CDS YP_002413334.1 218705815 7157327 complement(2700895..2701395) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2701395 nuoE 7157327 nuoE Escherichia coli UMN026 NADH dehydrogenase subunit E YP_002413334.1 2700895 R 585056 CDS YP_002413335.1 218705816 7157326 complement(2701398..2703200) 1 NC_011751.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2703200 nuoC 7157326 nuoC Escherichia coli UMN026 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_002413335.1 2701398 R 585056 CDS YP_002413336.1 218705817 7157325 complement(2703294..2703956) 1 NC_011751.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2703956 nuoB 7157325 nuoB Escherichia coli UMN026 NADH dehydrogenase subunit B YP_002413336.1 2703294 R 585056 CDS YP_002413337.1 218705818 7157324 complement(2703972..2704415) 1 NC_011751.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2704415 nuoA 7157324 nuoA Escherichia coli UMN026 NADH dehydrogenase subunit A YP_002413337.1 2703972 R 585056 CDS YP_002413338.1 218705819 7157323 complement(2705045..2705983) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator; flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor 2705983 lrhA 7157323 lrhA Escherichia coli UMN026 flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor YP_002413338.1 2705045 R 585056 CDS YP_002413339.1 218705820 7157017 2706903..2708120 1 NC_011751.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2708120 yfbQ 7157017 yfbQ Escherichia coli UMN026 aminotransferase AlaT YP_002413339.1 2706903 D 585056 CDS YP_002413340.1 218705821 7158896 2708204..2708803 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme; hypothetical protein 2708803 yfbR 7158896 yfbR Escherichia coli UMN026 hypothetical protein YP_002413340.1 2708204 D 585056 CDS YP_002413341.1 218705822 7158897 complement(2708862..2710694) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 2710694 yfbS 7158897 yfbS Escherichia coli UMN026 putative transporter YP_002413341.1 2708862 R 585056 CDS YP_002413342.1 218705823 7158898 complement(2710781..2711431) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphatase 2711431 yfbT 7158898 yfbT Escherichia coli UMN026 putative phosphatase YP_002413342.1 2710781 R 585056 CDS YP_002413343.1 218705824 7158899 complement(2711442..2711936) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2711936 yfbU 7158899 yfbU Escherichia coli UMN026 hypothetical protein YP_002413343.1 2711442 R 585056 CDS YP_002413344.1 218705825 7158900 complement(2712019..2712474) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2712474 yfbV 7158900 yfbV Escherichia coli UMN026 hypothetical protein YP_002413344.1 2712019 R 585056 CDS YP_002413345.1 218705826 7158901 2712812..2714014 1 NC_011751.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2714014 ackA 7158901 ackA Escherichia coli UMN026 acetate kinase YP_002413345.1 2712812 D 585056 CDS YP_002413346.1 218705827 7155680 2714089..2716233 1 NC_011751.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2716233 pta 7155680 pta Escherichia coli UMN026 phosphate acetyltransferase YP_002413346.1 2714089 D 585056 CDS YP_002413347.1 218705828 7157561 2716423..2717943 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pc : putative carrier; hypothetical protein 2717943 yfcC 7157561 yfcC Escherichia coli UMN026 hypothetical protein YP_002413347.1 2716423 D 585056 CDS YP_002413348.1 218705829 7158904 complement(2717976..2718518) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme; putative NUDIX hydrolase 2718518 yfcD 7158904 yfcD Escherichia coli UMN026 putative NUDIX hydrolase YP_002413348.1 2717976 R 585056 CDS YP_002413349.1 218705830 7158905 complement(2718576..2719130) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; phosphodiesterase 2719130 yfcE 7158905 yfcE Escherichia coli UMN026 phosphodiesterase YP_002413349.1 2718576 R 585056 CDS YP_002413350.1 218705831 7158906 complement(2719183..2719827) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2719827 yfcF 7158906 yfcF Escherichia coli UMN026 hypothetical protein YP_002413350.1 2719183 R 585056 CDS YP_002413351.1 218705832 7158907 2719963..2720610 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; glutathione S-transferase 2720610 yfcG 7158907 yfcG Escherichia coli UMN026 glutathione S-transferase YP_002413351.1 2719963 D 585056 CDS YP_002413352.1 218705833 7158908 2720667..2721029 1 NC_011751.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2721029 folX 7158908 folX Escherichia coli UMN026 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_002413352.1 2720667 D 585056 CDS YP_002413353.1 218705834 7156431 2721050..2721943 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; hypothetical protein 2721943 yfcH 7156431 yfcH Escherichia coli UMN026 hypothetical protein YP_002413353.1 2721050 D 585056 CDS YP_002413354.1 218705835 7158909 complement(2721991..2722881) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase 2722881 yfcI 7158909 yfcI Escherichia coli UMN026 putative transposase YP_002413354.1 2721991 R 585056 CDS YP_002413355.1 218705836 7158910 complement(2723077..2723850) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter; histidine/lysine/arginine/ornithine transporter subunit 2723850 hisP 7158910 hisP Escherichia coli UMN026 histidine/lysine/arginine/ornithine transporter subunit YP_002413355.1 2723077 R 585056 CDS YP_002413356.1 218705837 7156684 complement(2723858..2724574) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 2724574 hisM 7156684 hisM Escherichia coli UMN026 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_002413356.1 2723858 R 585056 CDS YP_002413357.1 218705838 7156683 complement(2724571..2725257) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 2725257 hisQ 7156683 hisQ Escherichia coli UMN026 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_002413357.1 2724571 R 585056 CDS YP_002413358.1 218705839 7156685 complement(2725347..2726129) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein 2726129 hisJ 7156685 hisJ Escherichia coli UMN026 histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_002413358.1 2725347 R 585056 CDS YP_002413359.1 218705840 7156681 complement(2726350..2727132) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter; lysine/arginine/ornithine ABC transporter periplasmic-binding protein 2727132 argT 7156681 argT Escherichia coli UMN026 lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_002413359.1 2726350 R 585056 CDS YP_002413360.1 218705841 7155781 complement(2727398..2727967) 1 NC_011751.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 2727967 ubiX 7155781 ubiX Escherichia coli UMN026 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002413360.1 2727398 R 585056 CDS YP_002413361.1 218705842 7158160 complement(2728062..2729579) 1 NC_011751.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 2729579 purF 7158160 purF Escherichia coli UMN026 amidophosphoribosyltransferase YP_002413361.1 2728062 R 585056 CDS YP_002413362.1 218705843 7157577 complement(2729616..2730104) 1 NC_011751.1 membrane protein required for colicin V production; colicin V production protein 2730104 cvpA 7157577 cvpA Escherichia coli UMN026 colicin V production protein YP_002413362.1 2729616 R 585056 CDS YP_002413363.1 218705844 7156058 complement(2730363..2731025) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734; hypothetical protein 2731025 dedD 7156058 dedD Escherichia coli UMN026 hypothetical protein YP_002413363.1 2730363 R 585056 CDS YP_002413364.1 218705845 7156135 complement(2731015..2732283) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 2732283 folC 7156135 folC Escherichia coli UMN026 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_002413364.1 2731015 R 585056 CDS YP_002413365.1 218705846 7156425 complement(2732353..2733267) 1 NC_011751.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2733267 accD 7156425 accD Escherichia coli UMN026 acetyl-CoA carboxylase subunit beta YP_002413365.1 2732353 R 585056 CDS YP_002413366.1 218705847 7155674 complement(2733423..2734082) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : putative membrane component; hypothetical protein 2734082 dedA 7155674 dedA Escherichia coli UMN026 hypothetical protein YP_002413366.1 2733423 R 585056 CDS YP_002413367.1 218705848 7156134 complement(2734165..2734977) 1 NC_011751.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2734977 truA 7156134 truA Escherichia coli UMN026 tRNA pseudouridine synthase A YP_002413367.1 2734165 R 585056 CDS YP_002413368.1 218705849 7158125 complement(2734977..2735990) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : putative enzyme; putative semialdehyde dehydrogenase 2735990 usg 7158125 usg Escherichia coli UMN026 putative semialdehyde dehydrogenase YP_002413368.1 2734977 R 585056 CDS YP_002413369.1 218705850 7158191 complement(2736056..2737192) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme; erythronate-4-phosphate dehydrogenase 2737192 pdxB 7158191 pdxB Escherichia coli UMN026 erythronate-4-phosphate dehydrogenase YP_002413369.1 2736056 R 585056 CDS YP_002413370.1 218705851 7157405 2737291..2738286 1 NC_011751.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2738286 flk 7157405 flk Escherichia coli UMN026 flagella biosynthesis regulator YP_002413370.1 2737291 D 585056 CDS YP_002413371.1 218705852 7156416 complement(2738283..2739461) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 2739461 yfcJ 7156416 yfcJ Escherichia coli UMN026 hypothetical protein YP_002413371.1 2738283 R 585056 CDS YP_002413372.1 218705853 7158911 complement(2739746..2740966) 1 NC_011751.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 2740966 fabB 7158911 fabB Escherichia coli UMN026 3-oxoacyl-(acyl carrier protein) synthase I YP_002413372.1 2739746 R 585056 CDS YP_002413373.1 218705854 7156294 2741125..2743131 1 NC_011751.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2743131 mnmC 7156294 mnmC Escherichia coli UMN026 5-methylaminomethyl-2-thiouridine methyltransferase YP_002413373.1 2741125 D 585056 CDS YP_002413374.1 218705855 7158112 complement(2743252..2743530) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2743530 yfcL 7158112 yfcL Escherichia coli UMN026 hypothetical protein YP_002413374.1 2743252 R 585056 CDS YP_002413375.1 218705856 7158912 complement(2743564..2744112) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2744112 yfcM 7158912 yfcM Escherichia coli UMN026 hypothetical protein YP_002413375.1 2743564 R 585056 CDS YP_002413376.1 218705857 7158913 complement(2744112..2744921) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2744921 yfcA 7158913 yfcA Escherichia coli UMN026 hypothetical protein YP_002413376.1 2744112 R 585056 CDS YP_002413377.1 218705858 7158903 complement(2744921..2745745) 1 NC_011751.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 2745745 mepA 7158903 mepA Escherichia coli UMN026 penicillin-insensitive murein endopeptidase YP_002413377.1 2744921 R 585056 CDS YP_002413378.1 218705859 7157099 complement(2745749..2746834) 1 NC_011751.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2746834 aroC 7157099 aroC Escherichia coli UMN026 chorismate synthase YP_002413378.1 2745749 R 585056 CDS YP_002413379.1 218705860 7155785 complement(2746869..2747801) 1 NC_011751.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2747801 prmB 7155785 prmB Escherichia coli UMN026 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002413379.1 2746869 R 585056 CDS YP_002413380.1 218705861 7157528 2747967..2748518 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2748518 yfcN 7157528 yfcN Escherichia coli UMN026 hypothetical protein YP_002413380.1 2747967 D 585056 CDS YP_002413381.1 218705862 7158914 complement(2748659..2749522) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2749522 7158914 ECUMN_2672 Escherichia coli UMN026 hypothetical protein YP_002413381.1 2748659 R 585056 CDS YP_002413382.1 218705863 7155153 complement(2749509..2750033) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial protein 2750033 7155153 ECUMN_2673 Escherichia coli UMN026 putative fimbrial protein YP_002413382.1 2749509 R 585056 CDS YP_002413383.1 218705864 7155154 complement(2750030..2750500) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial protein 2750500 7155154 ECUMN_2674 Escherichia coli UMN026 putative fimbrial protein YP_002413383.1 2750030 R 585056 CDS YP_002413384.1 218705865 7155155 complement(2750497..2751111) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative minor fimbrial subunit 2751111 7155155 ECUMN_2675 Escherichia coli UMN026 putative minor fimbrial subunit YP_002413384.1 2750497 R 585056 CDS YP_002413385.1 218705866 7155156 complement(2751020..2751769) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative periplasmic pilus exported chaperone 2751769 yfcS 7155156 yfcS Escherichia coli UMN026 putative periplasmic pilus exported chaperone YP_002413385.1 2751020 R 585056 CDS YP_002413386.1 218705867 7158915 complement(2751789..2754440) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2754440 7158915 ECUMN_2677 Escherichia coli UMN026 hypothetical protein YP_002413386.1 2751789 R 585056 CDS YP_002413387.1 218705868 7155157 complement(2754512..2755078) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2755078 7155157 ECUMN_2678 Escherichia coli UMN026 hypothetical protein YP_002413387.1 2754512 R 585056 CDS YP_002413388.1 218705869 7155158 complement(2755740..2756225) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme; phosphohistidine phosphatase 2756225 sixA 7155158 sixA Escherichia coli UMN026 phosphohistidine phosphatase YP_002413388.1 2755740 R 585056 CDS YP_002413389.1 218705870 7157933 complement(2756428..2758572) 1 NC_011751.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 2758572 fadJ 7157933 fadJ Escherichia coli UMN026 multifunctional fatty acid oxidation complex subunit alpha YP_002413389.1 2756428 R 585056 CDS YP_002413390.1 218705871 7158916 complement(2758572..2759882) 1 NC_011751.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 2759882 fadI 7158916 fadI Escherichia coli UMN026 3-ketoacyl-CoA thiolase YP_002413390.1 2758572 R 585056 CDS YP_002413391.1 218705872 7158917 complement(2760063..2760347) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2760347 yfcZ 7158917 yfcZ Escherichia coli UMN026 hypothetical protein YP_002413391.1 2760063 R 585056 CDS YP_002413392.1 218705873 7158918 2760713..2762059 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter; long-chain fatty acid outer membrane transporter 2762059 fadL 7158918 fadL Escherichia coli UMN026 long-chain fatty acid outer membrane transporter YP_002413392.1 2760713 D 585056 CDS YP_002413393.1 218705874 7156307 2762426..2763673 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2763673 yfdF 7156307 yfdF Escherichia coli UMN026 hypothetical protein YP_002413393.1 2762426 D 585056 CDS YP_002413394.1 218705875 7158921 complement(2763852..2764607) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein; putative lipoprotein 2764607 vacJ 7158921 vacJ Escherichia coli UMN026 putative lipoprotein YP_002413394.1 2763852 R 585056 CDS YP_002413395.1 218705876 7158209 complement(2764633..2764803) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2764803 7158209 ECUMN_2687 Escherichia coli UMN026 hypothetical protein YP_002413395.1 2764633 R 585056 CDS YP_002413396.1 218705877 7155159 2764901..2765833 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2765833 yfdC 7155159 yfdC Escherichia coli UMN026 hypothetical protein YP_002413396.1 2764901 D 585056 CDS YP_002413397.1 218705878 7155578 2766193..2766345 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2766345 7155578 ECUMN_2689 Escherichia coli UMN026 hypothetical protein YP_002413397.1 2766193 D 585056 CDS YP_002413398.1 218705879 7155160 complement(2766425..2767672) 1 NC_011751.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease 2767672 lacY 7155160 lacY Escherichia coli UMN026 galactoside permease YP_002413398.1 2766425 R 585056 CDS YP_002413399.1 218705880 7156021 complement(2767734..2768657) 1 NC_011751.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase 2768657 cscK 7156021 cscK Escherichia coli UMN026 aminoimidazole riboside kinase YP_002413399.1 2767734 R 585056 CDS YP_002413400.1 218705881 7156022 2768864..2770306 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12218016; Product type e : enzyme; Sucrose-6-phosphate hydrolase 2770306 cscA 7156022 cscA Escherichia coli UMN026 Sucrose-6-phosphate hydrolase YP_002413400.1 2768864 D 585056 CDS YP_002413401.1 218705882 7156020 complement(2770314..2771507) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; Sucrose operon repressor 2771507 cscR 7156020 cscR Escherichia coli UMN026 Sucrose operon repressor YP_002413401.1 2770314 R 585056 CDS YP_002413402.1 218705883 7156207 2771788..2773119 1 NC_011751.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2773119 dsdA 7156207 dsdA Escherichia coli UMN026 D-serine dehydratase YP_002413402.1 2771788 D 585056 CDS YP_002413403.1 218705884 7156206 complement(2773225..2774763) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20378313; Product type pt : putative transporter; putative multidrug efflux system 2774763 emrY 7156206 emrY Escherichia coli UMN026 putative multidrug efflux system YP_002413403.1 2773225 R 585056 CDS YP_002413404.1 218705885 7156244 complement(2774763..2775926) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20378313; Product type t : transporter; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component 2775926 emrK 7156244 emrK Escherichia coli UMN026 EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component YP_002413404.1 2774763 R 585056 CDS YP_002413405.1 218705886 7156243 2776342..2776956 1 NC_011751.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2776956 evgA 7156243 evgA Escherichia coli UMN026 DNA-binding transcriptional activator EvgA YP_002413405.1 2776342 D 585056 CDS YP_002413406.1 218705887 7156285 2776961..2780554 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14523115, 93173621, 9501520, 10923791, 1289796, 8125343, 9535079; Product type r : regulator; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2780554 evgS 7156285 evgS Escherichia coli UMN026 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_002413406.1 2776961 D 585056 CDS YP_002413407.1 218705888 7156286 complement(2780609..2781754) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 2781754 yfdE 7156286 yfdE Escherichia coli UMN026 hypothetical protein YP_002413407.1 2780609 R 585056 CDS YP_002413408.1 218705889 7158920 complement(2781828..2782772) 1 NC_011751.1 member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV 2782772 yfdV 7158920 yfdV Escherichia coli UMN026 putative transporter YfdV YP_002413408.1 2781828 R 585056 CDS YP_002413409.1 218705890 7158929 complement(2782841..2784535) 1 NC_011751.1 catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase 2784535 oxc 7158929 oxc Escherichia coli UMN026 putative oxalyl-CoA decarboxylase YP_002413409.1 2782841 R 585056 CDS YP_002413410.1 218705891 7157369 complement(2784589..2785839) 1 NC_011751.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase 2785839 frc 7157369 frc Escherichia coli UMN026 formyl-coenzyme A transferase YP_002413410.1 2784589 R 585056 CDS YP_002413411.1 218705892 7156433 complement(2786351..2786983) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11157960; hypothetical protein 2786983 yfdX 7156433 yfdX Escherichia coli UMN026 hypothetical protein YP_002413411.1 2786351 R 585056 CDS YP_002413412.1 218705893 7158930 2787279..2787554 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15183873; Product type lp : lipoprotein; putative lipoprotein 2787554 ypdI 7158930 ypdI Escherichia coli UMN026 putative lipoprotein YP_002413412.1 2787279 D 585056 CDS YP_002413413.1 218705894 7159576 complement(2787631..2787873) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; Product type pm : putative membrane component; hypothetical protein 2787873 yfdY 7159576 yfdY Escherichia coli UMN026 hypothetical protein YP_002413413.1 2787631 R 585056 CDS YP_002413415.1 218705896 7155161 2788226..2789146 1 NC_011751.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2789146 ddg 7155161 ddg Escherichia coli UMN026 lipid A biosynthesis palmitoleoyl acyltransferase YP_002413415.1 2788226 D 585056 CDS YP_002413416.1 218705897 7158100 complement(2789638..2790876) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; aminotransferase 2790876 yfdZ 7158100 yfdZ Escherichia coli UMN026 aminotransferase YP_002413416.1 2789638 R 585056 CDS YP_002413417.1 218705898 7158932 2791253..2792950 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : putative receptor; putative sensory kinase in two-component system with YpdB 2792950 ypdA 7158932 ypdA Escherichia coli UMN026 putative sensory kinase in two-component system with YpdB YP_002413417.1 2791253 D 585056 CDS YP_002413418.1 218705899 7159568 2792965..2793699 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : putative regulator; putative response regulator in two-component system with YpdA 2793699 ypdB 7159568 ypdB Escherichia coli UMN026 putative response regulator in two-component system with YpdA YP_002413418.1 2792965 D 585056 CDS YP_002413419.1 218705900 7159569 2793712..2794569 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding protein 2794569 ypdC 7159569 ypdC Escherichia coli UMN026 putative DNA-binding protein YP_002413419.1 2793712 D 585056 CDS YP_002413420.1 218705901 7159570 complement(2794572..2797067) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative fused PTS system Hpr component/enzyme I component/enzyme IIA component 2797067 ypdD 7159570 ypdD Escherichia coli UMN026 putative fused PTS system Hpr component/enzyme I component/enzyme IIA component YP_002413420.1 2794572 R 585056 CDS YP_002413421.1 218705902 7159571 complement(2797092..2798129) 1 NC_011751.1 metalloprotein; exoaminopeptidase 2798129 ypdE 7159571 ypdE Escherichia coli UMN026 exoaminopeptidase YP_002413421.1 2797092 R 585056 CDS YP_002413422.1 218705903 7159572 complement(2798129..2799214) 1 NC_011751.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 2799214 ypdF 7159572 ypdF Escherichia coli UMN026 aminopeptidase YP_002413422.1 2798129 R 585056 CDS YP_002413423.1 218705904 7159573 complement(2799229..2800476) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIC component of PTS 2800476 ypdG 7159573 ypdG Escherichia coli UMN026 putative enzyme IIC component of PTS YP_002413423.1 2799229 R 585056 CDS YP_002413424.1 218705905 7159574 complement(2800498..2800824) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIB component of PTS 2800824 ypdH 7159574 ypdH Escherichia coli UMN026 putative enzyme IIB component of PTS YP_002413424.1 2800498 R 585056 CDS YP_002413425.1 218705906 7159575 complement(2801044..2802009) 1 NC_011751.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 2802009 glk 7159575 glk Escherichia coli UMN026 glucokinase YP_002413425.1 2801044 R 585056 CDS YP_002413426.1 218705907 7156543 2802213..2803469 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 2803469 yfeO 7156543 yfeO Escherichia coli UMN026 hypothetical protein YP_002413426.1 2802213 D 585056 CDS YP_002413427.1 218705908 7158939 2803584..2803910 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2803910 ypeC 7158939 ypeC Escherichia coli UMN026 hypothetical protein YP_002413427.1 2803584 D 585056 CDS YP_002413428.1 218705909 7159578 complement(2804052..2805290) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter; manganese transport protein MntH 2805290 mntH 7159578 mntH Escherichia coli UMN026 manganese transport protein MntH YP_002413428.1 2804052 R 585056 CDS YP_002413429.1 218705910 7157143 2805626..2806828 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter; nucleoside (except guanosine) transporter 2806828 nupC 7157143 nupC Escherichia coli UMN026 nucleoside (except guanosine) transporter YP_002413429.1 2805626 D 585056 CDS YP_002413430.1 218705911 7157336 complement(2806878..2809067) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative diguanylate cyclase 2809067 yfeA 7157336 yfeA Escherichia coli UMN026 putative diguanylate cyclase YP_002413430.1 2806878 R 585056 CDS YP_002413431.1 218705912 7155632 2809701..2810045 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative nucleic acid-binding transcriptional regulator 2810045 yfeC 7155632 yfeC Escherichia coli UMN026 putative nucleic acid-binding transcriptional regulator YP_002413431.1 2809701 D 585056 CDS YP_002413432.1 218705913 7158934 2810047..2810439 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative nucleic acid-binding transcriptional regulator 2810439 yfeD 7158934 yfeD Escherichia coli UMN026 putative nucleic acid-binding transcriptional regulator YP_002413432.1 2810047 D 585056 CDS YP_002413433.1 218705914 7158935 complement(2810490..2811905) 1 NC_011751.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 2811905 gltX 7158935 gltX Escherichia coli UMN026 glutamyl-tRNA synthetase YP_002413433.1 2810490 R 585056 CDS YP_002413434.1 218705915 7155582 2812681..2813022 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative flxA protein 2813022 7155582 ECUMN_2729 Escherichia coli UMN026 putative flxA protein YP_002413434.1 2812681 D 585056 CDS YP_002413435.1 218705916 7155162 complement(2813013..2813939) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2813939 yfeR 7155162 yfeR Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413435.1 2813013 R 585056 CDS YP_002413436.1 218705917 7158940 2814029..2815027 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative sodium/bile acid symporter family protein 2815027 yfeH 7158940 yfeH Escherichia coli UMN026 putative sodium/bile acid symporter family protein YP_002413436.1 2814029 D 585056 CDS YP_002413437.1 218705918 7158937 complement(2815024..2815335) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2815335 7158937 ECUMN_2732 Escherichia coli UMN026 hypothetical protein YP_002413437.1 2815024 R 585056 CDS YP_002413438.1 218705919 7155163 complement(2815244..2817259) 1 NC_011751.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 2817259 ligA 7155163 ligA Escherichia coli UMN026 NAD-dependent DNA ligase LigA YP_002413438.1 2815244 R 585056 CDS YP_002413439.1 218705920 7156979 complement(2817330..2818316) 1 NC_011751.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 2818316 zipA 7156979 zipA Escherichia coli UMN026 cell division protein ZipA YP_002413439.1 2817330 R 585056 CDS YP_002413440.1 218705921 7159685 2818558..2819319 1 NC_011751.1 putative role in sulfur assimilation; putative sulfate transport protein CysZ 2819319 cysZ 7159685 cysZ Escherichia coli UMN026 putative sulfate transport protein CysZ YP_002413440.1 2818558 D 585056 CDS YP_002413441.1 218705922 7156095 2819504..2820475 1 NC_011751.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2820475 cysK 7156095 cysK Escherichia coli UMN026 cysteine synthase A YP_002413441.1 2819504 D 585056 CDS YP_002413442.1 218705923 7156087 2820859..2821116 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2821116 ptsH 7156087 ptsH Escherichia coli UMN026 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr YP_002413442.1 2820859 D 585056 CDS YP_002413443.1 218705924 7157568 2821161..2822888 1 NC_011751.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2822888 ptsI 7157568 ptsI Escherichia coli UMN026 phosphoenolpyruvate-protein phosphotransferase YP_002413443.1 2821161 D 585056 CDS YP_002413444.1 218705925 7157569 2822929..2823438 1 NC_011751.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2823438 crr 7157569 crr Escherichia coli UMN026 PTS system glucose-specific transporter subunit YP_002413444.1 2822929 D 585056 CDS YP_002413445.1 218705926 7156019 complement(2823480..2824331) 1 NC_011751.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 2824331 pdxK 7156019 pdxK Escherichia coli UMN026 pyridoxal kinase YP_002413445.1 2823480 R 585056 CDS YP_002413446.1 218705927 7157408 2824436..2824804 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2824804 yfeK 7157408 yfeK Escherichia coli UMN026 hypothetical protein YP_002413446.1 2824436 D 585056 CDS YP_002413447.1 218705928 7158938 complement(2824807..2825718) 1 NC_011751.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 2825718 cysM 7158938 cysM Escherichia coli UMN026 cysteine synthase B YP_002413447.1 2824807 R 585056 CDS YP_002413448.1 218705929 7156088 complement(2825852..2826949) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter; sulfate/thiosulfate transporter subunit 2826949 cysA 7156088 cysA Escherichia coli UMN026 sulfate/thiosulfate transporter subunit YP_002413448.1 2825852 R 585056 CDS YP_002413449.1 218705930 7156078 complement(2826939..2827814) 1 NC_011751.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate permease 2827814 cysW 7156078 cysW Escherichia coli UMN026 sulfate/thiosulfate permease YP_002413449.1 2826939 R 585056 CDS YP_002413450.1 218705931 7156094 complement(2827814..2828647) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter; sulfate/thiosulfate transporter subunit 2828647 cysU 7156094 cysU Escherichia coli UMN026 sulfate/thiosulfate transporter subunit YP_002413450.1 2827814 R 585056 CDS YP_002413451.1 218705932 7156093 complement(2828647..2829663) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter; thiosulfate transporter subunit 2829663 cysP 7156093 cysP Escherichia coli UMN026 thiosulfate transporter subunit YP_002413451.1 2828647 R 585056 CDS YP_002413452.1 218705933 7156090 complement(2829834..2830625) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : putative enzyme; short chain dehydrogenase 2830625 ucpA 7156090 ucpA Escherichia coli UMN026 short chain dehydrogenase YP_002413452.1 2829834 R 585056 CDS YP_002413453.1 218705934 7158161 complement(2830754..2831611) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2831611 yfeT 7158161 yfeT Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413453.1 2830754 R 585056 CDS YP_002413454.1 218705935 7158941 2831775..2832671 1 NC_011751.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2832671 murQ 7158941 murQ Escherichia coli UMN026 N-acetylmuramic acid-6-phosphate etherase YP_002413454.1 2831775 D 585056 CDS YP_002413455.1 218705936 7158942 2832675..2834099 1 NC_011751.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2834099 murP 7158942 murP Escherichia coli UMN026 PTS system N-acetylmuramic acid transporter subunits EIIBC YP_002413455.1 2832675 D 585056 CDS YP_002413456.1 218705937 7157209 2834017..2835405 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15983044, 15060041; Product type e : enzyme; hypothetical protein 2835405 murQ 7157209 murQ Escherichia coli UMN026 hypothetical protein YP_002413456.1 2834017 D 585056 CDS YP_002413457.1 218705938 7157210 complement(2835463..2836362) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2836362 yfeX 7157210 yfeX Escherichia coli UMN026 hypothetical protein YP_002413457.1 2835463 R 585056 CDS YP_002413458.1 218705939 7158943 complement(2836458..2837033) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507; hypothetical protein 2837033 yfeY 7158943 yfeY Escherichia coli UMN026 hypothetical protein YP_002413458.1 2836458 R 585056 CDS YP_002413459.1 218705940 7158944 complement(2837094..2837543) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2837543 yfeZ 7158944 yfeZ Escherichia coli UMN026 hypothetical protein YP_002413459.1 2837094 R 585056 CDS YP_002413460.1 218705941 7158945 complement(2837530..2837955) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 2837955 ypeA 7158945 ypeA Escherichia coli UMN026 putative acetyltransferase YP_002413460.1 2837530 R 585056 CDS YP_002413461.1 218705942 7159577 2838169..2839038 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase I 2839038 amiA 7159577 amiA Escherichia coli UMN026 N-acetylmuramoyl-l-alanine amidase I YP_002413461.1 2838169 D 585056 CDS YP_002413462.1 218705943 7155733 2839042..2839941 1 NC_011751.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2839941 hemF 7155733 hemF Escherichia coli UMN026 coproporphyrinogen III oxidase YP_002413462.1 2839042 D 585056 CDS YP_002413463.1 218705944 7156655 complement(2839947..2840999) 1 NC_011751.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 2840999 yfeG 7156655 yfeG Escherichia coli UMN026 transcriptional regulator EutR YP_002413463.1 2839947 R 585056 CDS YP_002413464.1 218705945 7158936 complement(2841045..2841545) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : putative structure; putative ethanolaminosome structural protein 2841545 yffI 7158936 yffI Escherichia coli UMN026 putative ethanolaminosome structural protein YP_002413464.1 2841045 R 585056 CDS YP_002413465.1 218705946 7158948 complement(2841558..2842217) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein 2842217 eutL 7158948 eutL Escherichia coli UMN026 putative carboxysome-like ethanolaminosome structural protein YP_002413465.1 2841558 R 585056 CDS YP_002413466.1 218705947 7156281 complement(2842227..2843114) 1 NC_011751.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 2843114 eutC 7156281 eutC Escherichia coli UMN026 ethanolamine ammonia-lyase small subunit YP_002413466.1 2842227 R 585056 CDS YP_002413467.1 218705948 7156275 complement(2843135..2844496) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme; ethanolamine ammonia-lyase, large subunit, heavy chain 2844496 eutB 7156275 eutB Escherichia coli UMN026 ethanolamine ammonia-lyase, large subunit, heavy chain YP_002413467.1 2843135 R 585056 CDS YP_002413468.1 218705949 7156274 complement(2844508..2845911) 1 NC_011751.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 2845911 eutA 7156274 eutA Escherichia coli UMN026 reactivating factor for ethanolamine ammonia lyase YP_002413468.1 2844508 R 585056 CDS YP_002413469.1 218705950 7156273 complement(2845908..2847134) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : putative transporter; putative ethanolamine transporter 2847134 eutH 7156273 eutH Escherichia coli UMN026 putative ethanolamine transporter YP_002413469.1 2845908 R 585056 CDS YP_002413470.1 218705951 7156278 complement(2847650..2848837) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative alcohol dehydrogenase in ethanolamine utilization; ethanolaminosome 2848837 eutG 7156278 eutG Escherichia coli UMN026 putative alcohol dehydrogenase in ethanolamine utilization; ethanolaminosome YP_002413470.1 2847650 R 585056 CDS YP_002413471.1 218705952 7156277 complement(2848827..2849663) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : putative factor; putative chaperonin, ethanolamine utilization protein 2849663 eutJ 7156277 eutJ Escherichia coli UMN026 putative chaperonin, ethanolamine utilization protein YP_002413471.1 2848827 R 585056 CDS YP_002413472.1 218705953 7156280 complement(2849674..2851077) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative aldehyde dehydrogenase, ethanolamine utilization protein 2851077 eutE 7156280 eutE Escherichia coli UMN026 putative aldehyde dehydrogenase, ethanolamine utilization protein YP_002413472.1 2849674 R 585056 CDS YP_002413473.1 218705954 7156276 complement(2851089..2851376) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein 2851376 cchB 7156276 cchB Escherichia coli UMN026 putative carboxysome-like ethanolaminosome structural protein YP_002413473.1 2851089 R 585056 CDS YP_002413474.1 218705955 7155927 complement(2851483..2851776) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein 2851776 cchA 7155927 cchA Escherichia coli UMN026 putative carboxysome-like ethanolaminosome structural protein YP_002413474.1 2851483 R 585056 CDS YP_002413475.1 218705956 7155926 complement(2851815..2852831) 1 NC_011751.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 2852831 eutD 7155926 eutD Escherichia coli UMN026 phosphotransacetylase YP_002413475.1 2851815 R 585056 CDS YP_002413476.1 218705957 7156279 complement(2852828..2853631) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative cobalamin adenosyltransferase 2853631 eutT 7156279 eutT Escherichia coli UMN026 putative cobalamin adenosyltransferase YP_002413476.1 2852828 R 585056 CDS YP_002413477.1 218705958 7156284 complement(2853628..2854329) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203; hypothetical protein 2854329 eutQ 7156284 eutQ Escherichia coli UMN026 hypothetical protein YP_002413477.1 2853628 R 585056 CDS YP_002413478.1 218705959 7156283 complement(2854304..2854783) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme; putative nucleoside triphosphate hydrolase domain protein 2854783 eutP 7156283 eutP Escherichia coli UMN026 putative nucleoside triphosphate hydrolase domain protein YP_002413478.1 2854304 R 585056 CDS YP_002413479.1 218705960 7156282 complement(2854796..2855131) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure; putative carboxysome-like ethanolaminosome structural protein 2855131 ypfE 7156282 ypfE Escherichia coli UMN026 putative carboxysome-like ethanolaminosome structural protein YP_002413479.1 2854796 R 585056 CDS YP_002413480.1 218705961 7159579 complement(2855424..2857703) 1 NC_011751.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 2857703 maeB 7159579 maeB Escherichia coli UMN026 malic enzyme YP_002413480.1 2855424 R 585056 CDS YP_002413481.1 218705962 7157039 2857992..2858942 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme; transaldolase A 2858942 talA 7157039 talA Escherichia coli UMN026 transaldolase A YP_002413481.1 2857992 D 585056 CDS YP_002413482.1 218705963 7158019 2858962..2860965 1 NC_011751.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2860965 tktB 7158019 tktB Escherichia coli UMN026 transketolase YP_002413482.1 2858962 D 585056 CDS YP_002413483.1 218705964 7158075 complement(2861068..2862111) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2862111 ypfG 7158075 ypfG Escherichia coli UMN026 hypothetical protein YP_002413483.1 2861068 R 585056 CDS YP_002413484.1 218705965 7159580 complement(2862237..2862812) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NUDIX hydrolase 2862812 yffH 7159580 yffH Escherichia coli UMN026 putative NUDIX hydrolase YP_002413484.1 2862237 R 585056 CDS YP_002413485.1 218705966 7158947 complement(2862880..2864859) 1 NC_011751.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 2864859 aegA 7158947 aegA Escherichia coli UMN026 putative oxidoreductase Fe-S binding subunit YP_002413485.1 2862880 R 585056 CDS YP_002413486.1 218705967 7155705 2865065..2866765 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator; nitrate/nitrite sensor protein NarQ 2866765 narQ 7155705 narQ Escherichia coli UMN026 nitrate/nitrite sensor protein NarQ YP_002413486.1 2865065 D 585056 CDS YP_002413487.1 218705968 7157254 2866929..2870042 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter; aminoglycoside/multidrug efflux system 2870042 acrD 7157254 acrD Escherichia coli UMN026 aminoglycoside/multidrug efflux system YP_002413487.1 2866929 D 585056 CDS YP_002413488.1 218705969 7155689 2870581..2870937 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2870937 yffB 7155689 yffB Escherichia coli UMN026 hypothetical protein YP_002413488.1 2870581 D 585056 CDS YP_002413489.1 218705970 7158946 2870941..2872068 1 NC_011751.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2872068 dapE 7158946 dapE Escherichia coli UMN026 succinyl-diaminopimelate desuccinylase YP_002413489.1 2870941 D 585056 CDS YP_002413490.1 218705971 7156110 2872096..2872296 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2872296 ypfN 7156110 ypfN Escherichia coli UMN026 hypothetical protein YP_002413490.1 2872096 D 585056 CDS YP_002413491.1 218705972 7159584 complement(2872377..2873075) 1 NC_011751.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 2873075 ypfH 7159584 ypfH Escherichia coli UMN026 esterase YpfH YP_002413491.1 2872377 R 585056 CDS YP_002413492.1 218705973 7159581 complement(2873149..2875164) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 2875164 ypfI 7159581 ypfI Escherichia coli UMN026 putative hydrolase YP_002413492.1 2873149 R 585056 CDS YP_002413493.1 218705974 7159582 complement(2875179..2876042) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2876042 ypfJ 7159582 ypfJ Escherichia coli UMN026 hypothetical protein YP_002413493.1 2875179 R 585056 CDS YP_002413494.1 218705975 7159583 complement(2876210..2876923) 1 NC_011751.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 2876923 purC 7159583 purC Escherichia coli UMN026 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002413494.1 2876210 R 585056 CDS YP_002413495.1 218705976 7157574 complement(2877136..2878170) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein; lipoprotein 2878170 nlpB 7157574 nlpB Escherichia coli UMN026 lipoprotein YP_002413495.1 2877136 R 585056 CDS YP_002413496.1 218705977 7157286 complement(2878187..2879065) 1 NC_011751.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 2879065 dapA 7157286 dapA Escherichia coli UMN026 dihydrodipicolinate synthase YP_002413496.1 2878187 R 585056 CDS YP_002413497.1 218705978 7156107 2879211..2879783 1 NC_011751.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2879783 gcvR 7156107 gcvR Escherichia coli UMN026 glycine cleavage system transcriptional repressor YP_002413497.1 2879211 D 585056 CDS YP_002413498.1 218705979 7156524 2879783..2880253 1 NC_011751.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2880253 bcp 7156524 bcp Escherichia coli UMN026 thioredoxin-dependent thiol peroxidase YP_002413498.1 2879783 D 585056 CDS YP_002413499.1 218705980 7155855 2880506..2881123 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241, 2016588; Product type c : carrier; hydrogenase 4, 4Fe-4S subunit 2881123 hyfA 7155855 hyfA Escherichia coli UMN026 hydrogenase 4, 4Fe-4S subunit YP_002413499.1 2880506 D 585056 CDS YP_002413500.1 218705981 7156758 2881123..2883141 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit B 2883141 hyfB 7156758 hyfB Escherichia coli UMN026 hydrogenase 4 subunit B YP_002413500.1 2881123 D 585056 CDS YP_002413501.1 218705982 7156759 2883152..2884099 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4, membrane subunit 2884099 hyfC 7156759 hyfC Escherichia coli UMN026 hydrogenase 4, membrane subunit YP_002413501.1 2883152 D 585056 CDS YP_002413502.1 218705983 7156760 2884116..2885555 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit D 2885555 hyfD 7156760 hyfD Escherichia coli UMN026 hydrogenase 4 subunit D YP_002413502.1 2884116 D 585056 CDS YP_002413503.1 218705984 7156761 2885567..2886217 1 NC_011751.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2886217 hyfE 7156761 hyfE Escherichia coli UMN026 hydrogenase 4 membrane subunit YP_002413503.1 2885567 D 585056 CDS YP_002413504.1 218705985 7156762 2886222..2887802 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit F 2887802 hyfF 7156762 hyfF Escherichia coli UMN026 hydrogenase 4 subunit F YP_002413504.1 2886222 D 585056 CDS YP_002413505.1 218705986 7156763 2887840..2889507 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, subunit 2889507 hyfG 7156763 hyfG Escherichia coli UMN026 hydrogenase 4, subunit YP_002413505.1 2887840 D 585056 CDS YP_002413506.1 218705987 7156764 2889517..2890062 1 NC_011751.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2890062 hyfH 7156764 hyfH Escherichia coli UMN026 hydrogenase 4 subunit H YP_002413506.1 2889517 D 585056 CDS YP_002413507.1 218705988 7156765 2890059..2890817 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, Fe-S subunit 2890817 hyfI 7156765 hyfI Escherichia coli UMN026 hydrogenase 4, Fe-S subunit YP_002413507.1 2890059 D 585056 CDS YP_002413508.1 218705989 7156766 2890810..2891223 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9387241; Product type pf : putative factor; putative processing element hydrogenase 4 2891223 hyfJ 7156766 hyfJ Escherichia coli UMN026 putative processing element hydrogenase 4 YP_002413508.1 2890810 D 585056 CDS YP_002413509.1 218705990 7156767 2891253..2893265 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type r : regulator; DNA-binding transcriptional activator, formate sensing 2893265 hyfR 7156767 hyfR Escherichia coli UMN026 DNA-binding transcriptional activator, formate sensing YP_002413509.1 2891253 D 585056 CDS YP_002413510.1 218705991 7156768 2893287..2894135 1 NC_011751.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2894135 focB 7156768 focB Escherichia coli UMN026 putative formate transporter YP_002413510.1 2893287 D 585056 CDS YP_002413511.1 218705992 7156422 complement(2894172..2895233) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 2895233 perM 7156422 perM Escherichia coli UMN026 putative permease YP_002413511.1 2894172 R 585056 CDS YP_002413512.1 218705993 7157418 2895446..2896909 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2896909 yfgC 7157418 yfgC Escherichia coli UMN026 putative peptidase YP_002413512.1 2895446 D 585056 CDS YP_002413513.1 218705994 7158951 2896930..2897289 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2897289 yfgD 7158951 yfgD Escherichia coli UMN026 putative oxidoreductase YP_002413513.1 2896930 D 585056 CDS YP_002413514.1 218705995 7158952 complement(2897395..2898141) 1 NC_011751.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 2898141 hda 7158952 hda Escherichia coli UMN026 DNA replication initiation factor YP_002413514.1 2897395 R 585056 CDS YP_002413515.1 218705996 7156643 complement(2898191..2899480) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter; uracil transporter 2899480 uraA 7156643 uraA Escherichia coli UMN026 uracil transporter YP_002413515.1 2898191 R 585056 CDS YP_002413516.1 218705997 7158190 complement(2899566..2900192) 1 NC_011751.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2900192 upp 7158190 upp Escherichia coli UMN026 uracil phosphoribosyltransferase YP_002413516.1 2899566 R 585056 CDS YP_002413517.1 218705998 7158189 2900517..2901554 1 NC_011751.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2901554 purM 7158189 purM Escherichia coli UMN026 phosphoribosylaminoimidazole synthetase YP_002413517.1 2900517 D 585056 CDS YP_002413518.1 218705999 7157581 2901554..2902192 1 NC_011751.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2902192 purN 7157581 purN Escherichia coli UMN026 phosphoribosylglycinamide formyltransferase YP_002413518.1 2901554 D 585056 CDS YP_002413519.1 218706000 7157582 2902364..2904430 1 NC_011751.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2904430 ppk 7157582 ppk Escherichia coli UMN026 polyphosphate kinase YP_002413519.1 2902364 D 585056 CDS YP_002413520.1 218706001 7157509 2904435..2905976 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme; exopolyphosphatase 2905976 ppx 7157509 ppx Escherichia coli UMN026 exopolyphosphatase YP_002413520.1 2904435 D 585056 CDS YP_002413521.1 218706002 7157512 complement(2906015..2908258) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2908258 yfgF 7157512 yfgF Escherichia coli UMN026 hypothetical protein YP_002413521.1 2906015 R 585056 CDS YP_002413522.1 218706003 7158953 complement(2908475..2908765) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2908765 7158953 ECUMN_2818 Escherichia coli UMN026 hypothetical protein YP_002413522.1 2908475 R 585056 CDS YP_002413523.1 218706004 7155164 2909112..2909630 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 2909630 yfgH 7155164 yfgH Escherichia coli UMN026 putative outer membrane lipoprotein YP_002413523.1 2909112 D 585056 CDS YP_002413524.1 218706005 7158954 2909646..2910185 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2910185 yfgI 7158954 yfgI Escherichia coli UMN026 hypothetical protein YP_002413524.1 2909646 D 585056 CDS YP_002413525.1 218706006 7158955 complement(2910333..2910842) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 2910842 7158955 ECUMN_2821 Escherichia coli UMN026 transposase IS605 family, IS200 group YP_002413525.1 2910333 R 585056 CDS YP_002413526.1 218706007 7155165 complement(2910748..2910936) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 2910936 7155165 ECUMN_2822 Escherichia coli UMN026 hypothetical protein YP_002413526.1 2910748 R 585056 CDS YP_002413527.1 218706008 7155166 complement(2910989..2912566) 1 NC_011751.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 2912566 guaA 7155166 guaA Escherichia coli UMN026 GMP synthase YP_002413527.1 2910989 R 585056 CDS YP_002413528.1 218706009 7156622 complement(2912635..2914101) 1 NC_011751.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 2914101 guaB 7156622 guaB Escherichia coli UMN026 inosine 5'-monophosphate dehydrogenase YP_002413528.1 2912635 R 585056 CDS YP_002413529.1 218706010 7156623 2914263..2915639 1 NC_011751.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2915639 xseA 7156623 xseA Escherichia coli UMN026 exodeoxyribonuclease VII large subunit YP_002413529.1 2914263 D 585056 CDS YP_002413530.1 218706011 7155168 complement(2923862..2924839) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12540539; Product type pm : putative membrane component; putative outer membrane protein (sivI-like) 2924839 7155168 ECUMN_2828 Escherichia coli UMN026 putative outer membrane protein (sivI-like) YP_002413530.1 2923862 R 585056 CDS YP_002413531.1 218706012 7155169 complement(2924894..2927101) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : putative factor; putative intimin 2927101 7155169 ECUMN_2829 Escherichia coli UMN026 putative intimin YP_002413531.1 2924894 R 585056 CDS YP_002413532.1 218706013 7155170 complement(2927281..2927496) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2927496 7155170 ECUMN_2830 Escherichia coli UMN026 hypothetical protein YP_002413532.1 2927281 R 585056 CDS YP_002413533.1 218706014 7155171 complement(2927559..2929031) 1 NC_011751.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 2929031 engA 7155171 engA Escherichia coli UMN026 GTP-binding protein EngA YP_002413533.1 2927559 R 585056 CDS YP_002413534.1 218706015 7156146 complement(2929149..2930327) 1 NC_011751.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 2930327 yfgL 7156146 yfgL Escherichia coli UMN026 outer membrane protein assembly complex subunit YfgL YP_002413534.1 2929149 R 585056 CDS YP_002413535.1 218706016 7158956 complement(2930338..2930958) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2930958 yfgM 7158956 yfgM Escherichia coli UMN026 hypothetical protein YP_002413535.1 2930338 R 585056 CDS YP_002413536.1 218706017 7158957 complement(2930976..2932250) 1 NC_011751.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 2932250 hisS 7158957 hisS Escherichia coli UMN026 histidyl-tRNA synthetase YP_002413536.1 2930976 R 585056 CDS YP_002413537.1 218706018 7156686 complement(2932361..2933479) 1 NC_011751.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2933479 ispG 7156686 ispG Escherichia coli UMN026 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002413537.1 2932361 R 585056 CDS YP_002413538.1 218706019 7156867 complement(2933506..2934519) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; cytoskeletal protein RodZ 2934519 yfgA 7156867 yfgA Escherichia coli UMN026 cytoskeletal protein RodZ YP_002413538.1 2933506 R 585056 CDS YP_002413539.1 218706020 7158949 complement(2934804..2935958) 1 NC_011751.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 2935958 yfgB 7158949 yfgB Escherichia coli UMN026 ribosomal RNA large subunit methyltransferase N YP_002413539.1 2934804 R 585056 CDS YP_002413540.1 218706021 7158950 complement(2936108..2936539) 1 NC_011751.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2936539 ndk 7158950 ndk Escherichia coli UMN026 nucleoside diphosphate kinase YP_002413540.1 2936108 R 585056 CDS YP_002413541.1 218706022 7157262 complement(2936688..2939000) 1 NC_011751.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 2939000 pbpC 7157262 pbpC Escherichia coli UMN026 penicillin-binding protein 1C YP_002413541.1 2936688 R 585056 CDS YP_002413542.1 218706023 7157394 complement(2939001..2943962) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2943962 yfhM 7157394 yfhM Escherichia coli UMN026 hypothetical protein YP_002413542.1 2939001 R 585056 CDS YP_002413543.1 218706024 7158966 2944169..2945014 1 NC_011751.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2945014 sseA 7158966 sseA Escherichia coli UMN026 3-mercaptopyruvate sulfurtransferase YP_002413543.1 2944169 D 585056 CDS YP_002413544.1 218706025 7157844 complement(2945774..2946550) 1 NC_011751.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 2946550 sseB 7157844 sseB Escherichia coli UMN026 enhanced serine sensitivity protein SseB YP_002413544.1 2945774 R 585056 CDS YP_002413545.1 218706026 7157984 complement(2946692..2947975) 1 NC_011751.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 2947975 pepB 7157984 pepB Escherichia coli UMN026 aminopeptidase B YP_002413545.1 2946692 R 585056 CDS YP_002413546.1 218706027 7157411 complement(2948220..2948420) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : putative factor; hypothetical protein 2948420 yfhJ 7157411 yfhJ Escherichia coli UMN026 hypothetical protein YP_002413546.1 2948220 R 585056 CDS YP_002413547.1 218706028 7158963 complement(2948432..2948767) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier; [2Fe-2S] ferredoxin 2948767 fdx 7158963 fdx Escherichia coli UMN026 [2Fe-2S] ferredoxin YP_002413547.1 2948432 R 585056 CDS YP_002413548.1 218706029 7156323 complement(2948769..2950619) 1 NC_011751.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 2950619 hscA 7156323 hscA Escherichia coli UMN026 chaperone protein HscA YP_002413548.1 2948769 R 585056 CDS YP_002413549.1 218706030 7156714 complement(2950636..2951151) 1 NC_011751.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 2951151 hscB 7156714 hscB Escherichia coli UMN026 co-chaperone HscB YP_002413549.1 2950636 R 585056 CDS YP_002413550.1 218706031 7156715 complement(2951247..2951570) 1 NC_011751.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 2951570 iscA 7156715 iscA Escherichia coli UMN026 iron-sulfur cluster assembly protein YP_002413550.1 2951247 R 585056 CDS YP_002413551.1 218706032 7156857 complement(2951587..2951973) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor; scaffold protein 2951973 iscU 7156857 iscU Escherichia coli UMN026 scaffold protein YP_002413551.1 2951587 R 585056 CDS YP_002413552.1 218706033 7156860 complement(2952001..2953215) 1 NC_011751.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 2953215 iscS 7156860 iscS Escherichia coli UMN026 cysteine desulfurase YP_002413552.1 2952001 R 585056 CDS YP_002413553.1 218706034 7156859 complement(2953327..2953815) 1 NC_011751.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 2953815 iscR 7156859 iscR Escherichia coli UMN026 DNA-binding transcriptional regulator IscR YP_002413553.1 2953327 R 585056 CDS YP_002413554.1 218706035 7156858 complement(2954085..2954825) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : putative enzyme; putative methyltransferase 2954825 yfhQ 7156858 yfhQ Escherichia coli UMN026 putative methyltransferase YP_002413554.1 2954085 R 585056 CDS YP_002413555.1 218706036 7158967 2954944..2955747 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme; inositol monophosphatase 2955747 suhB 7158967 suhB Escherichia coli UMN026 inositol monophosphatase YP_002413555.1 2954944 D 585056 CDS YP_002413556.1 218706037 7158010 2955892..2956746 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidase 2956746 yfhR 7158010 yfhR Escherichia coli UMN026 putative peptidase YP_002413556.1 2955892 D 585056 CDS YP_002413557.1 218706038 7158968 2956937..2958217 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95020540, 96154950; Product type cp : cell process; stationary phase inducible protein CsiE 2958217 csiE 7158968 csiE Escherichia coli UMN026 stationary phase inducible protein CsiE YP_002413557.1 2956937 D 585056 CDS YP_002413558.1 218706039 7156032 complement(2958209..2959348) 1 NC_011751.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 2959348 hcaT 7156032 hcaT Escherichia coli UMN026 putative 3-phenylpropionic acid transporter YP_002413558.1 2958209 R 585056 CDS YP_002413559.1 218706040 7156639 complement(2959508..2960398) 1 NC_011751.1 activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR 2960398 hcaR 7156639 hcaR Escherichia coli UMN026 DNA-binding transcriptional regulator HcaR YP_002413559.1 2959508 R 585056 CDS YP_002413560.1 218706041 7156638 2960534..2961895 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83238171, 87008429, 98269008; Product type e : enzyme; 3-phenylpropionate dioxygenase, large subunit alpha 2961895 hcaE 7156638 hcaE Escherichia coli UMN026 3-phenylpropionate dioxygenase, large subunit alpha YP_002413560.1 2960534 D 585056 CDS YP_002413561.1 218706042 7156636 2961892..2962410 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83238171, 87008429, 98269008, 9603882; Product type e : enzyme; 3-phenylpropionate dioxygenase subunit beta 2962410 hcaF 7156636 hcaF Escherichia coli UMN026 3-phenylpropionate dioxygenase subunit beta YP_002413561.1 2961892 D 585056 CDS YP_002413562.1 218706043 7156637 2962410..2962730 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98269008, 9603882; Product type pc : putative carrier; 3-phenylpropionate dioxygenase ferredoxin subunit 2962730 hcaC 7156637 hcaC Escherichia coli UMN026 3-phenylpropionate dioxygenase ferredoxin subunit YP_002413562.1 2962410 D 585056 CDS YP_002413563.1 218706044 7156634 2962727..2963539 1 NC_011751.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2963539 hcaB 7156634 hcaB Escherichia coli UMN026 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase YP_002413563.1 2962727 D 585056 CDS YP_002413564.1 218706045 7156633 2963549..2964751 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98269008, 9603882; Product type e : enzyme; phenylpropionate dioxygenase ferredoxin reductase subunit 2964751 hcaD 7156633 hcaD Escherichia coli UMN026 phenylpropionate dioxygenase ferredoxin reductase subunit YP_002413564.1 2963549 D 585056 CDS YP_002413565.1 218706046 7156635 2964803..2965270 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 2965270 yphA 7156635 yphA Escherichia coli UMN026 hypothetical protein YP_002413565.1 2964803 D 585056 CDS YP_002413566.1 218706047 7159585 complement(2965317..2966189) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2966189 yphB 7159585 yphB Escherichia coli UMN026 hypothetical protein YP_002413566.1 2965317 R 585056 CDS YP_002413567.1 218706048 7159586 complement(2966201..2967262) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 2967262 yphC 7159586 yphC Escherichia coli UMN026 putative oxidoreductase YP_002413567.1 2966201 R 585056 CDS YP_002413568.1 218706049 7159587 complement(2967328..2968326) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter membrane protein 2968326 yphD 7159587 yphD Escherichia coli UMN026 putative sugar ABC transporter membrane protein YP_002413568.1 2967328 R 585056 CDS YP_002413569.1 218706050 7159588 complement(2968351..2969862) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter ATP-binding protein 2969862 yphE 7159588 yphE Escherichia coli UMN026 putative sugar ABC transporter ATP-binding protein YP_002413569.1 2968351 R 585056 CDS YP_002413570.1 218706051 7159589 complement(2969885..2970868) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter; putative sugar ABC transporter periplasmic-binding protein 2970868 yphF 7159589 yphF Escherichia coli UMN026 putative sugar ABC transporter periplasmic-binding protein YP_002413570.1 2969885 R 585056 CDS YP_002413571.1 218706052 7159590 complement(2970965..2974246) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2974246 yphG 7159590 yphG Escherichia coli UMN026 hypothetical protein YP_002413571.1 2970965 R 585056 CDS YP_002413572.1 218706053 7159591 2974364..2975557 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2975557 yphH 7159591 yphH Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413572.1 2974364 D 585056 CDS YP_002413573.1 218706054 7159592 complement(2975755..2977008) 1 NC_011751.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2977008 glyA 7159592 glyA Escherichia coli UMN026 serine hydroxymethyltransferase YP_002413573.1 2975755 R 585056 CDS YP_002413574.1 218706055 7156585 2977337..2978527 1 NC_011751.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2978527 hmp 7156585 hmp Escherichia coli UMN026 nitric oxide dioxygenase YP_002413574.1 2977337 D 585056 CDS YP_002413575.1 218706056 7156689 complement(2978572..2978910) 1 NC_011751.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 2978910 glnB 7156689 glnB Escherichia coli UMN026 nitrogen regulatory protein P-II 1 YP_002413575.1 2978572 R 585056 CDS YP_002413576.1 218706057 7156549 complement(2978971..2980305) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : putative regulator; putative DNA-binding response regulator in two-component system 2980305 yfhA 7156549 yfhA Escherichia coli UMN026 putative DNA-binding response regulator in two-component system YP_002413576.1 2978971 R 585056 CDS YP_002413577.1 218706058 7158958 complement(2980295..2981008) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2981008 yfhG 7158958 yfhG Escherichia coli UMN026 hypothetical protein YP_002413577.1 2980295 R 585056 CDS YP_002413578.1 218706059 7158961 complement(2981173..2982600) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative sensory kinase in two-component system 2982600 yfhK 7158961 yfhK Escherichia coli UMN026 putative sensory kinase in two-component system YP_002413578.1 2981173 R 585056 CDS YP_002413579.1 218706060 7158073 complement(2983176..2987063) 1 NC_011751.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 2987063 purL 7158073 purL Escherichia coli UMN026 phosphoribosylformylglycinamidine synthase YP_002413579.1 2983176 R 585056 CDS YP_002413580.1 218706061 7157580 2987459..2988877 1 NC_011751.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2988877 yfhD 7157580 yfhD Escherichia coli UMN026 putative transglycosylase YP_002413580.1 2987459 D 585056 CDS YP_002413581.1 218706062 7158960 complement(2988874..2989410) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme; tRNA -specific adenosine deaminase 2989410 tadA 7158960 tadA Escherichia coli UMN026 tRNA -specific adenosine deaminase YP_002413581.1 2988874 R 585056 CDS YP_002413582.1 218706063 7158017 complement(2989435..2990070) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2990070 yfhB 7158017 yfhB Escherichia coli UMN026 hypothetical protein YP_002413582.1 2989435 R 585056 CDS YP_002413583.1 218706064 7158959 2990279..2991127 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 2991127 yfhH 7158959 yfhH Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413583.1 2990279 D 585056 CDS YP_002413584.1 218706065 7158962 2991183..2991443 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier; ferredoxin 2991443 yfhL 7158962 yfhL Escherichia coli UMN026 ferredoxin YP_002413584.1 2991183 D 585056 CDS YP_002413585.1 218706066 7157845 complement(2991715..2991879) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2991879 7157845 ECUMN_2883 Escherichia coli UMN026 hypothetical protein YP_002413585.1 2991715 R 585056 CDS YP_002413586.1 218706067 7157846 complement(2992138..2992518) 1 NC_011751.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2992518 acpS 7157846 acpS Escherichia coli UMN026 4'-phosphopantetheinyl transferase YP_002413586.1 2992138 R 585056 CDS YP_002413587.1 218706068 7155685 complement(2992518..2993249) 1 NC_011751.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 2993249 pdxJ 7155685 pdxJ Escherichia coli UMN026 pyridoxine 5'-phosphate synthase YP_002413587.1 2992518 R 585056 CDS YP_002413588.1 218706069 7157407 complement(2993261..2993989) 1 NC_011751.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2993989 recO 7157407 recO Escherichia coli UMN026 DNA repair protein RecO YP_002413588.1 2993261 R 585056 CDS YP_002413589.1 218706070 7157645 complement(2994001..2994906) 1 NC_011751.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 2994906 era 7157645 era Escherichia coli UMN026 GTP-binding protein Era YP_002413589.1 2994001 R 585056 CDS YP_002413590.1 218706071 7156267 complement(2994903..2995583) 1 NC_011751.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 2995583 rnc 7156267 rnc Escherichia coli UMN026 ribonuclease III YP_002413590.1 2994903 R 585056 CDS YP_002413591.1 218706072 7157708 complement(2995856..2996830) 1 NC_011751.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 2996830 lepB 7157708 lepB Escherichia coli UMN026 signal peptidase I YP_002413591.1 2995856 R 585056 CDS YP_002413592.1 218706073 7156941 complement(2996846..2998645) 1 NC_011751.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 2998645 lepA 7156941 lepA Escherichia coli UMN026 GTP-binding protein LepA YP_002413592.1 2996846 R 585056 CDS YP_002413593.1 218706074 7156940 complement(2998843..2999322) 1 NC_011751.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 2999322 rseC 7156940 rseC Escherichia coli UMN026 SoxR reducing system protein RseC YP_002413593.1 2998843 R 585056 CDS YP_002413594.1 218706075 7157794 complement(2999319..3000275) 1 NC_011751.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 3000275 rseB 7157794 rseB Escherichia coli UMN026 periplasmic negative regulator of sigmaE YP_002413594.1 2999319 R 585056 CDS YP_002413595.1 218706076 7157793 complement(3000275..3000925) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor; anti-RNA polymerase sigma factor SigE 3000925 rseA 7157793 rseA Escherichia coli UMN026 anti-RNA polymerase sigma factor SigE YP_002413595.1 3000275 R 585056 CDS YP_002413596.1 218706077 7157792 complement(3000958..3001533) 1 NC_011751.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3001533 rpoE 7157792 rpoE Escherichia coli UMN026 RNA polymerase sigma factor RpoE YP_002413596.1 3000958 R 585056 CDS YP_002413597.1 218706078 7157222 complement(3003549..3004286) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative S-adenosyl-L-methionine-dependent methyltransferase 3004286 yfiC 7157222 yfiC Escherichia coli UMN026 putative S-adenosyl-L-methionine-dependent methyltransferase YP_002413597.1 3003549 R 585056 CDS YP_002413598.1 218706079 7158971 3004418..3005752 1 NC_011751.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3005752 srmB 7158971 srmB Escherichia coli UMN026 ATP-dependent RNA helicase SrmB YP_002413598.1 3004418 D 585056 CDS YP_002413599.1 218706080 7157979 3005931..3006461 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 3006461 7157979 ECUMN_2900 Escherichia coli UMN026 transposase ORF A, IS1397 YP_002413599.1 3005931 D 585056 CDS YP_002413600.1 218706081 7155173 3006566..3007288 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 3007288 7155173 ECUMN_2901 Escherichia coli UMN026 transposase ORF B, IS3 family, IS150 group YP_002413600.1 3006566 D 585056 CDS YP_002413601.1 218706082 7155174 complement(3007397..3008278) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3008278 yfiE 7155174 yfiE Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413601.1 3007397 R 585056 CDS YP_002413602.1 218706083 7158973 3008381..3008968 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12562784; Product type t : transporter; neutral amino-acid efflux protein 3008968 yfiK 7158973 yfiK Escherichia coli UMN026 neutral amino-acid efflux protein YP_002413602.1 3008381 D 585056 CDS YP_002413603.1 218706084 7158976 complement(3009022..3009405) 1 NC_011751.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 3009405 yfiD 7158976 yfiD Escherichia coli UMN026 autonomous glycyl radical cofactor GrcA YP_002413603.1 3009022 R 585056 CDS YP_002413604.1 218706085 7158972 3009710..3010399 1 NC_011751.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3010399 ung 7158972 ung Escherichia coli UMN026 uracil-DNA glycosylase YP_002413604.1 3009710 D 585056 CDS YP_002413605.1 218706086 7158188 complement(3010447..3011484) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 3011484 yfiF 7158188 yfiF Escherichia coli UMN026 putative methyltransferase YP_002413605.1 3010447 R 585056 CDS YP_002413606.1 218706087 7158974 complement(3011474..3011677) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3011677 7158974 ECUMN_2907 Escherichia coli UMN026 hypothetical protein YP_002413606.1 3011474 R 585056 CDS YP_002413607.1 218706088 7155175 3011691..3012110 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier; thioredoxin 2 3012110 trxC 7155175 trxC Escherichia coli UMN026 thioredoxin 2 YP_002413607.1 3011691 D 585056 CDS YP_002413608.1 218706089 7158131 3012179..3012877 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3012877 yfiP 7158131 yfiP Escherichia coli UMN026 hypothetical protein YP_002413608.1 3012179 D 585056 CDS YP_002413609.1 218706090 7158981 3012909..3015569 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acyl-CoA synthetase NAD(P)-binding/ATP-binding subunit 3015569 yfiQ 7158981 yfiQ Escherichia coli UMN026 acyl-CoA synthetase NAD(P)-binding/ATP-binding subunit YP_002413609.1 3012909 D 585056 CDS YP_002413610.1 218706091 7158982 3015683..3017038 1 NC_011751.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3017038 pssA 7158982 pssA Escherichia coli UMN026 phosphatidylserine synthase YP_002413610.1 3015683 D 585056 CDS YP_002413611.1 218706092 7157556 3017063..3017407 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3017407 yfiM 7157556 yfiM Escherichia coli UMN026 hypothetical protein YP_002413611.1 3017063 D 585056 CDS YP_002413612.1 218706093 7158978 complement(3017404..3018702) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter; alpha-ketoglutarate transporter 3018702 kgtP 7158978 kgtP Escherichia coli UMN026 alpha-ketoglutarate transporter YP_002413612.1 3017404 R 585056 CDS YP_002413613.1 218706094 7154984 complement(3024508..3027081) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor; protein disaggregation chaperone 3027081 clpB 7154984 clpB Escherichia coli UMN026 protein disaggregation chaperone YP_002413613.1 3024508 R 585056 CDS YP_002413614.1 218706095 7157847 complement(3027211..3027942) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329; hypothetical protein 3027942 yfiH 7157847 yfiH Escherichia coli UMN026 hypothetical protein YP_002413614.1 3027211 R 585056 CDS YP_002413615.1 218706096 7158975 complement(3027939..3028919) 1 NC_011751.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 3028919 rluD 7158975 rluD Escherichia coli UMN026 23S rRNA pseudouridine synthase D YP_002413615.1 3027939 R 585056 CDS YP_002413616.1 218706097 7157702 3029054..3029791 1 NC_011751.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3029791 yfiO 7157702 yfiO Escherichia coli UMN026 outer membrane protein assembly complex subunit YfiO YP_002413616.1 3029054 D 585056 CDS YP_002413617.1 218706098 7158980 3030062..3030403 1 NC_011751.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 3030403 yfiA 7158980 yfiA Escherichia coli UMN026 translation inhibitor protein RaiA YP_002413617.1 3030062 D 585056 CDS YP_002413619.1 218706100 7157434 3030653..3031813 1 NC_011751.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3031813 pheA 7157434 pheA Escherichia coli UMN026 bifunctional chorismate mutase/prephenate dehydratase YP_002413619.1 3030653 D 585056 CDS YP_002413620.1 218706101 7157433 complement(3031856..3032977) 1 NC_011751.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 3032977 tyrA 7157433 tyrA Escherichia coli UMN026 bifunctional chorismate mutase/prephenate dehydrogenase YP_002413620.1 3031856 R 585056 CDS YP_002413621.1 218706102 7158147 complement(3032988..3034058) 1 NC_011751.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3034058 aroF 7158147 aroF Escherichia coli UMN026 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002413621.1 3032988 R 585056 CDS YP_002413622.1 218706103 7155788 3034267..3034632 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6396419; hypothetical protein 3034632 yfiL 7155788 yfiL Escherichia coli UMN026 hypothetical protein YP_002413622.1 3034267 D 585056 CDS YP_002413623.1 218706104 7158977 3034779..3035297 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3035297 yfiR 7158977 yfiR Escherichia coli UMN026 hypothetical protein YP_002413623.1 3034779 D 585056 CDS YP_002413624.1 218706105 7158983 3035287..3036513 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; hypothetical protein 3036513 yfiN 7158983 yfiN Escherichia coli UMN026 hypothetical protein YP_002413624.1 3035287 D 585056 CDS YP_002413625.1 218706106 7158979 3036529..3037011 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96032391; Product type pm : putative membrane component; putative outer membrane lipoprotein 3037011 yfiB 7158979 yfiB Escherichia coli UMN026 putative outer membrane lipoprotein YP_002413625.1 3036529 D 585056 CDS YP_002413626.1 218706107 7158970 complement(3037087..3037434) 1 NC_011751.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3037434 rplS 7158970 rplS Escherichia coli UMN026 50S ribosomal protein L19 YP_002413626.1 3037087 R 585056 CDS YP_002413627.1 218706108 7157741 complement(3037476..3038243) 1 NC_011751.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3038243 trmD 7157741 trmD Escherichia coli UMN026 tRNA (guanine-N(1)-)-methyltransferase YP_002413627.1 3037476 R 585056 CDS YP_002413628.1 218706109 7158113 complement(3038274..3038822) 1 NC_011751.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3038822 rimM 7158113 rimM Escherichia coli UMN026 16S rRNA-processing protein RimM YP_002413628.1 3038274 R 585056 CDS YP_002413629.1 218706110 7157695 complement(3038841..3039089) 1 NC_011751.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3039089 rpsP 7157695 rpsP Escherichia coli UMN026 30S ribosomal protein S16 YP_002413629.1 3038841 R 585056 CDS YP_002413630.1 218706111 7157782 complement(3039338..3040699) 1 NC_011751.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 3040699 ffh 7157782 ffh Escherichia coli UMN026 signal recognition particle protein YP_002413630.1 3039338 R 585056 CDS YP_002413631.1 218706112 7156340 3040791..3041657 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3041657 ypjD 7156340 ypjD Escherichia coli UMN026 hypothetical protein YP_002413631.1 3040791 D 585056 CDS YP_002413632.1 218706113 7159594 3041768..3042964 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3042964 yfjD 7159594 yfjD Escherichia coli UMN026 hypothetical protein YP_002413632.1 3041768 D 585056 CDS YP_002413633.1 218706114 7158985 complement(3043019..3043612) 1 NC_011751.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 3043612 grpE 7158985 grpE Escherichia coli UMN026 heat shock protein GrpE YP_002413633.1 3043019 R 585056 CDS YP_002413634.1 218706115 7156613 3043735..3044613 1 NC_011751.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3044613 ppnK 7156613 ppnK Escherichia coli UMN026 inorganic polyphosphate/ATP-NAD kinase YP_002413634.1 3043735 D 585056 CDS YP_002413635.1 218706116 7158984 3044699..3046360 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process; recombination and repair protein 3046360 recN 7158984 recN Escherichia coli UMN026 recombination and repair protein YP_002413635.1 3044699 D 585056 CDS YP_002413636.1 218706117 7157644 3046509..3046850 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein; hypothetical protein 3046850 smpA 7157644 smpA Escherichia coli UMN026 hypothetical protein YP_002413636.1 3046509 D 585056 CDS YP_002413637.1 218706118 7157942 complement(3046912..3047202) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3047202 yfjF 7157942 yfjF Escherichia coli UMN026 hypothetical protein YP_002413637.1 3046912 R 585056 CDS YP_002413638.1 218706119 7158986 complement(3047192..3047668) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3047668 yfjG 7158986 yfjG Escherichia coli UMN026 hypothetical protein YP_002413638.1 3047192 R 585056 CDS YP_002413639.1 218706120 7158987 3047800..3048282 1 NC_011751.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3048282 smpB 7158987 smpB Escherichia coli UMN026 SsrA-binding protein YP_002413639.1 3047800 D 585056 CDS YP_002413640.1 218706121 7157988 3049026..3050273 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; prophage CP4-57 integrase 3050273 7157988 ECUMN_2945 Escherichia coli UMN026 prophage CP4-57 integrase YP_002413640.1 3049026 D 585056 CDS YP_002413641.1 218706122 7155176 3050320..3050919 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3050919 7155176 ECUMN_2946 Escherichia coli UMN026 hypothetical protein YP_002413641.1 3050320 D 585056 CDS YP_002413642.1 218706123 7155177 complement(3051269..3052441) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3052441 7155177 ECUMN_2947 Escherichia coli UMN026 hypothetical protein YP_002413642.1 3051269 R 585056 CDS YP_002413643.1 218706124 7155178 3052815..3053432 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3053432 7155178 ECUMN_2948 Escherichia coli UMN026 hypothetical protein YP_002413643.1 3052815 D 585056 CDS YP_002413644.1 218706125 7155179 3053407..3054033 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3054033 7155179 ECUMN_2949 Escherichia coli UMN026 hypothetical protein YP_002413644.1 3053407 D 585056 CDS YP_002413645.1 218706126 7155180 3054619..3056688 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3056688 7155180 ECUMN_2951 Escherichia coli UMN026 hypothetical protein YP_002413645.1 3054619 D 585056 CDS YP_002413646.1 218706127 7155181 3057361..3058347 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3058347 7155181 ECUMN_2952 Escherichia coli UMN026 hypothetical protein YP_002413646.1 3057361 D 585056 CDS YP_002413647.1 218706128 7155182 3058340..3059563 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3059563 7155182 ECUMN_2953 Escherichia coli UMN026 hypothetical protein YP_002413647.1 3058340 D 585056 CDS YP_002413648.1 218706129 7155183 3059590..3059805 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 3059805 7155183 ECUMN_2954 Escherichia coli UMN026 hypothetical protein YP_002413648.1 3059590 D 585056 CDS YP_002413649.1 218706130 7155184 3059798..3061000 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; putative ERCC4-like helicase 3061000 7155184 ECUMN_2955 Escherichia coli UMN026 putative ERCC4-like helicase YP_002413649.1 3059798 D 585056 CDS YP_002413650.1 218706131 7155185 3061039..3062322 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; putative Signal transduction histidine kinase 3062322 7155185 ECUMN_2956 Escherichia coli UMN026 putative Signal transduction histidine kinase YP_002413650.1 3061039 D 585056 CDS YP_002413651.1 218706132 7155186 complement(3062477..3062956) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3062956 7155186 ECUMN_2957 Escherichia coli UMN026 hypothetical protein YP_002413651.1 3062477 R 585056 CDS YP_002413652.1 218706133 7155187 3063317..3063838 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; glucitol/sorbitol permease IIC component from bacteriophage origin 3063838 7155187 ECUMN_2958 Escherichia coli UMN026 glucitol/sorbitol permease IIC component from bacteriophage origin YP_002413652.1 3063317 D 585056 CDS YP_002413653.1 218706134 7155188 3063988..3064209 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glucitol/sorbitol-specific phosphotransferase enzyme IIA component 3064209 7155188 ECUMN_2959 Escherichia coli UMN026 glucitol/sorbitol-specific phosphotransferase enzyme IIA component YP_002413653.1 3063988 D 585056 CDS YP_002413654.1 218706135 7155189 3064206..3065186 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9435786; Product type m : membrane component; glucitol/sorbitol-specific phosphotransferase enzyme IIB component 3065186 srlE 7155189 srlE Escherichia coli UMN026 glucitol/sorbitol-specific phosphotransferase enzyme IIB component YP_002413654.1 3064206 D 585056 CDS YP_002413655.1 218706136 7157976 3065197..3066210 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; putative dehydrogenase from bacteriophage origin 3066210 7157976 ECUMN_2961 Escherichia coli UMN026 putative dehydrogenase from bacteriophage origin YP_002413655.1 3065197 D 585056 CDS YP_002413656.1 218706137 7155190 3066453..3067706 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3067706 7155190 ECUMN_2962 Escherichia coli UMN026 hypothetical protein YP_002413656.1 3066453 D 585056 CDS YP_002413657.1 218706138 7155191 complement(3067778..3068413) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10572115; Product type pe : putative enzyme; putative 3-hexulose-6-phosphate synthase from bacteriophage origin 3068413 7155191 ECUMN_2963 Escherichia coli UMN026 putative 3-hexulose-6-phosphate synthase from bacteriophage origin YP_002413657.1 3067778 R 585056 CDS YP_002413658.1 218706139 7155192 complement(3068437..3069003) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10572115; Product type pe : putative enzyme; putative 3-hexulose-6-phosphate isomerase (PHI) from bacteriophage origin 3069003 7155192 ECUMN_2964 Escherichia coli UMN026 putative 3-hexulose-6-phosphate isomerase (PHI) from bacteriophage origin YP_002413658.1 3068437 R 585056 CDS YP_002413659.1 218706140 7155193 complement(3069000..3069842) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative Glucose-6-phosphate isomerase from bacteriophage origin 3069842 7155193 ECUMN_2965 Escherichia coli UMN026 putative Glucose-6-phosphate isomerase from bacteriophage origin YP_002413659.1 3069000 R 585056 CDS YP_002413660.1 218706141 7155194 complement(3069839..3071365) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; PTS system glucose-specific EIIABC component from bacteriophage origin 3071365 ptsG 7155194 ptsG Escherichia coli UMN026 PTS system glucose-specific EIIABC component from bacteriophage origin YP_002413660.1 3069839 R 585056 CDS YP_002413661.1 218706142 7157567 3071573..3073267 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component from bacteriophage origin 3073267 7157567 ECUMN_2967 Escherichia coli UMN026 putative dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic component from bacteriophage origin YP_002413661.1 3071573 D 585056 CDS YP_002413662.1 218706143 7155195 complement(3073619..3074158) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Bifunctional deaminase-reductase 3074158 7155195 ECUMN_2968 Escherichia coli UMN026 putative Bifunctional deaminase-reductase YP_002413662.1 3073619 R 585056 CDS YP_002413663.1 218706144 7155196 3074332..3075402 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3075402 7155196 ECUMN_2969 Escherichia coli UMN026 hypothetical protein YP_002413663.1 3074332 D 585056 CDS YP_002413664.1 218706145 7155197 complement(3075474..3075698) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3075698 7155197 ECUMN_2970 Escherichia coli UMN026 hypothetical protein YP_002413664.1 3075474 R 585056 CDS YP_002413665.1 218706146 7155198 complement(3075733..3076830) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3076830 7155198 ECUMN_2971 Escherichia coli UMN026 hypothetical protein YP_002413665.1 3075733 R 585056 CDS YP_002413666.1 218706147 7155199 complement(3077184..3077864) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; site-specific recombinase, phage integrase family 3077864 7155199 ECUMN_2972 Escherichia coli UMN026 site-specific recombinase, phage integrase family YP_002413666.1 3077184 R 585056 CDS YP_002413667.1 218706148 7155200 3078096..3078722 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3078722 7155200 ECUMN_2973 Escherichia coli UMN026 hypothetical protein YP_002413667.1 3078096 D 585056 CDS YP_002413668.1 218706149 7155201 3078747..3079022 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3079022 7155201 ECUMN_2974 Escherichia coli UMN026 hypothetical protein YP_002413668.1 3078747 D 585056 CDS YP_002413669.1 218706150 7155202 complement(3079355..3079693) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3079693 7155202 ECUMN_2975 Escherichia coli UMN026 hypothetical protein YP_002413669.1 3079355 R 585056 CDS YP_002413670.1 218706151 7155203 complement(3080198..3084901) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type t : transporter; adhesin-like autotransporter 3084901 ypjA 7155203 ypjA Escherichia coli UMN026 adhesin-like autotransporter YP_002413670.1 3080198 R 585056 CDS YP_002413671.1 218706152 7157466 complement(3085706..3087160) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3087160 7157466 ECUMN_2978 Escherichia coli UMN026 hypothetical protein YP_002413671.1 3085706 R 585056 CDS YP_002413672.1 218706153 7155204 complement(3087481..3087657) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3087657 7155204 ECUMN_2979 Escherichia coli UMN026 hypothetical protein YP_002413672.1 3087481 R 585056 CDS YP_002413673.1 218706154 7155205 3087517..3088533 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 3088533 insH 7155205 insH Escherichia coli UMN026 IS5 transposase and trans-activator; CP4-44 prophage YP_002413673.1 3087517 D 585056 CDS YP_002413674.1 218706155 7156832 complement(3089012..3089209) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3089209 7156832 ECUMN_2981 Escherichia coli UMN026 hypothetical protein YP_002413674.1 3089012 R 585056 CDS YP_002413675.1 218706156 7155629 3089751..3092003 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Alpha-amylase 3092003 7155629 ECUMN_2982 Escherichia coli UMN026 putative Alpha-amylase YP_002413675.1 3089751 D 585056 CDS YP_002413676.1 218706157 7155207 3092339..3093316 1 NC_011751.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3093316 ygaT 7155207 ygaT Escherichia coli UMN026 hypothetical protein YP_002413676.1 3092339 D 585056 CDS YP_002413677.1 218706158 7158994 3093336..3094604 1 NC_011751.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3094604 ygaF 7158994 ygaF Escherichia coli UMN026 hydroxyglutarate oxidase YP_002413677.1 3093336 D 585056 CDS YP_002413678.1 218706159 7158990 3094627..3096075 1 NC_011751.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3096075 gabD 7158990 gabD Escherichia coli UMN026 succinate-semialdehyde dehydrogenase I YP_002413678.1 3094627 D 585056 CDS YP_002413679.1 218706160 7156483 3096089..3097369 1 NC_011751.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3097369 gabT 7156483 gabT Escherichia coli UMN026 4-aminobutyrate aminotransferase YP_002413679.1 3096089 D 585056 CDS YP_002413680.1 218706161 7156485 3097680..3099080 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter; gamma-aminobutyrate transporter 3099080 gabP 7156485 gabP Escherichia coli UMN026 gamma-aminobutyrate transporter YP_002413680.1 3097680 D 585056 CDS YP_002413681.1 218706162 7156484 3099101..3099763 1 NC_011751.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3099763 csiR 7156484 csiR Escherichia coli UMN026 DNA-binding transcriptional regulator CsiR YP_002413681.1 3099101 D 585056 CDS YP_002413682.1 218706163 7156033 complement(3099764..3100213) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; LysM domain/BON superfamily protein 3100213 ygaU 7156033 ygaU Escherichia coli UMN026 LysM domain/BON superfamily protein YP_002413682.1 3099764 R 585056 CDS YP_002413683.1 218706164 7158995 complement(3100297..3100455) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3100455 yqaE 7158995 yqaE Escherichia coli UMN026 hypothetical protein YP_002413683.1 3100297 R 585056 CDS YP_002413684.1 218706165 7159597 3100638..3100937 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3100937 ygaV 7159597 ygaV Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413684.1 3100638 D 585056 CDS YP_002413685.1 218706166 7158996 3100947..3101471 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme; hypothetical protein 3101471 ygaP 7158996 ygaP Escherichia coli UMN026 hypothetical protein YP_002413685.1 3100947 D 585056 CDS YP_002413686.1 218706167 7158993 complement(3101518..3101922) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator; DNA binding protein, nucleoid-associated 3101922 stpA 7158993 stpA Escherichia coli UMN026 DNA binding protein, nucleoid-associated YP_002413686.1 3101518 R 585056 CDS YP_002413687.1 218706168 7157997 3102590..3103039 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3103039 ygaW 7157997 ygaW Escherichia coli UMN026 hypothetical protein YP_002413687.1 3102590 D 585056 CDS YP_002413688.1 218706169 7158997 complement(3103076..3103420) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433; hypothetical protein 3103420 ygaC 7158997 ygaC Escherichia coli UMN026 hypothetical protein YP_002413688.1 3103076 R 585056 CDS YP_002413689.1 218706170 7158988 3103560..3103901 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3103901 ygaM 7158988 ygaM Escherichia coli UMN026 hypothetical protein YP_002413689.1 3103560 D 585056 CDS YP_002413690.1 218706171 7158992 complement(3103958..3105292) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative fused protein: aminotransaminase/transcriptional regulator, GntR family 3105292 7158992 ECUMN_2997 Escherichia coli UMN026 putative fused protein: aminotransaminase/transcriptional regulator, GntR family YP_002413690.1 3103958 R 585056 CDS YP_002413691.1 218706172 7155208 3105380..3105811 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3105811 7155208 ECUMN_2998 Escherichia coli UMN026 hypothetical protein YP_002413691.1 3105380 D 585056 CDS YP_002413692.1 218706173 7155209 3106020..3106265 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : putative carrier; glutaredoxin-like protein 3106265 nrdH 7155209 nrdH Escherichia coli UMN026 glutaredoxin-like protein YP_002413692.1 3106020 D 585056 CDS YP_002413693.1 218706174 7157304 3106262..3106663 1 NC_011751.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3106663 nrdI 7157304 nrdI Escherichia coli UMN026 ribonucleotide reductase stimulatory protein YP_002413693.1 3106262 D 585056 CDS YP_002413694.1 218706175 7157305 3106645..3108789 1 NC_011751.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3108789 nrdE 7157305 nrdE Escherichia coli UMN026 ribonucleotide-diphosphate reductase subunit alpha YP_002413694.1 3106645 D 585056 CDS YP_002413695.1 218706176 7157301 3108799..3109758 1 NC_011751.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3109758 nrdF 7157301 nrdF Escherichia coli UMN026 ribonucleotide-diphosphate reductase subunit beta YP_002413695.1 3108799 D 585056 CDS YP_002413696.1 218706177 7157302 3110115..3111317 1 NC_011751.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3111317 proV 7157302 proV Escherichia coli UMN026 glycine betaine transporter ATP-binding subunit YP_002413696.1 3110115 D 585056 CDS YP_002413697.1 218706178 7157536 3111310..3112374 1 NC_011751.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3112374 proW 7157536 proW Escherichia coli UMN026 glycine betaine transporter membrane protein YP_002413697.1 3111310 D 585056 CDS YP_002413698.1 218706179 7157537 3112431..3113423 1 NC_011751.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3113423 proX 7157537 proX Escherichia coli UMN026 glycine betaine transporter periplasmic subunit YP_002413698.1 3112431 D 585056 CDS YP_002413699.1 218706180 7157538 3113876..3115060 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : putative transporter; putative transport protein 3115060 7157538 ECUMN_3006 Escherichia coli UMN026 putative transport protein YP_002413699.1 3113876 D 585056 CDS YP_002413700.1 218706181 7155210 3115184..3115921 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3115921 ygaZ 7155210 ygaZ Escherichia coli UMN026 putative transporter YP_002413700.1 3115184 D 585056 CDS YP_002413701.1 218706182 7158998 3115911..3116246 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3116246 ygaH 7158998 ygaH Escherichia coli UMN026 hypothetical protein YP_002413701.1 3115911 D 585056 CDS YP_002413702.1 218706183 7158991 3116337..3116867 1 NC_011751.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3116867 mprA 7158991 mprA Escherichia coli UMN026 transcriptional repressor MprA YP_002413702.1 3116337 D 585056 CDS YP_002413703.1 218706184 7157169 3116994..3118166 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter; multidrug efflux system 3118166 emrA 7157169 emrA Escherichia coli UMN026 multidrug efflux system YP_002413703.1 3116994 D 585056 CDS YP_002413704.1 218706185 7156240 3118183..3119721 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter; multidrug efflux system protein 3119721 emrB 7156240 emrB Escherichia coli UMN026 multidrug efflux system protein YP_002413704.1 3118183 D 585056 CDS YP_002413705.1 218706186 7156241 complement(3119785..3120300) 1 NC_011751.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 3120300 luxS 7156241 luxS Escherichia coli UMN026 S-ribosylhomocysteinase YP_002413705.1 3119785 R 585056 CDS YP_002413706.1 218706187 7157130 complement(3120450..3122006) 1 NC_011751.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 3122006 gshA 7157130 gshA Escherichia coli UMN026 glutamate--cysteine ligase YP_002413706.1 3120450 R 585056 CDS YP_002413707.1 218706188 7156617 complement(3122079..3122507) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3122507 yqaA 7156617 yqaA Escherichia coli UMN026 hypothetical protein YP_002413707.1 3122079 R 585056 CDS YP_002413708.1 218706189 7159595 complement(3122504..3123070) 1 NC_011751.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 3123070 yqaB 7159595 yqaB Escherichia coli UMN026 fructose-1-phosphatase YP_002413708.1 3122504 R 585056 CDS YP_002413709.1 218706190 7155624 complement(3124662..3124847) 1 NC_011751.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3124847 csrA 7155624 csrA Escherichia coli UMN026 carbon storage regulator YP_002413709.1 3124662 R 585056 CDS YP_002413710.1 218706191 7156043 complement(3125082..3127712) 1 NC_011751.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3127712 alaS 7156043 alaS Escherichia coli UMN026 alanyl-tRNA synthetase YP_002413710.1 3125082 R 585056 CDS YP_002413711.1 218706192 7155721 complement(3127840..3128340) 1 NC_011751.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3128340 recX 7155721 recX Escherichia coli UMN026 recombination regulator RecX YP_002413711.1 3127840 R 585056 CDS YP_002413712.1 218706193 7157648 complement(3128409..3129470) 1 NC_011751.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3129470 recA 7157648 recA Escherichia coli UMN026 recombinase A YP_002413712.1 3128409 R 585056 CDS YP_002413713.1 218706194 7157637 complement(3129550..3130047) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 3130047 ygaD 7157637 ygaD Escherichia coli UMN026 competence damage-inducible protein A YP_002413713.1 3129550 R 585056 CDS YP_002413714.1 218706195 7158989 complement(3130192..3131277) 1 NC_011751.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 3131277 mltB 7158989 mltB Escherichia coli UMN026 murein hydrolase B YP_002413714.1 3130192 R 585056 CDS YP_002413715.1 218706196 7157140 3131533..3132096 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87194727, 1334233, 3553176; Product type t : transporter; glucitol/sorbitol-specific enzyme IIC component of PTS 3132096 srlA 7157140 srlA Escherichia coli UMN026 glucitol/sorbitol-specific enzyme IIC component of PTS YP_002413715.1 3131533 D 585056 CDS YP_002413716.1 218706197 7157973 3132093..3133052 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1100602, 3553176; Product type t : transporter; glucitol/sorbitol-specific enzyme IIB component of PTS 3133052 srlE 7157973 srlE Escherichia coli UMN026 glucitol/sorbitol-specific enzyme IIB component of PTS YP_002413716.1 3132093 D 585056 CDS YP_002413717.1 218706198 7157977 3133063..3133434 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3133434 srlB 7157977 srlB Escherichia coli UMN026 PTS system glucitol/sorbitol-specific transporter subunit IIA YP_002413717.1 3133063 D 585056 CDS YP_002413718.1 218706199 7157974 3133438..3134217 1 NC_011751.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3134217 srlD 7157974 srlD Escherichia coli UMN026 sorbitol-6-phosphate dehydrogenase YP_002413718.1 3133438 D 585056 CDS YP_002413719.1 218706200 7157975 3134323..3134682 1 NC_011751.1 regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3134682 gutM 7157975 gutM Escherichia coli UMN026 DNA-binding transcriptional activator GutM YP_002413719.1 3134323 D 585056 CDS YP_002413720.1 218706201 7156629 3134749..3135522 1 NC_011751.1 regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3135522 srlR 7156629 srlR Escherichia coli UMN026 DNA-binding transcriptional repressor SrlR YP_002413720.1 3134749 D 585056 CDS YP_002413721.1 218706202 7157978 3135515..3136480 1 NC_011751.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3136480 gutQ 7157978 gutQ Escherichia coli UMN026 D-arabinose 5-phosphate isomerase YP_002413721.1 3135515 D 585056 CDS YP_002413722.1 218706203 7156630 complement(3136477..3137991) 1 NC_011751.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator 3137991 norR 7156630 norR Escherichia coli UMN026 anaerobic nitric oxide reductase transcription regulator YP_002413722.1 3136477 R 585056 CDS YP_002413723.1 218706204 7157294 3138178..3139617 1 NC_011751.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 3139617 norV 7157294 norV Escherichia coli UMN026 anaerobic nitric oxide reductase flavorubredoxin YP_002413723.1 3138178 D 585056 CDS YP_002413724.1 218706205 7157295 3139614..3140747 1 NC_011751.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3140747 norW 7157295 norW Escherichia coli UMN026 nitric oxide reductase YP_002413724.1 3139614 D 585056 CDS YP_002413725.1 218706206 7157296 complement(3140825..3143137) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme; carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases 3143137 hypF 7157296 hypF Escherichia coli UMN026 carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases YP_002413725.1 3140825 R 585056 CDS YP_002413726.1 218706207 7156775 complement(3143218..3143745) 1 NC_011751.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 3143745 hydN 7156775 hydN Escherichia coli UMN026 electron transport protein HydN YP_002413726.1 3143218 R 585056 CDS YP_002413727.1 218706208 7156757 complement(3143894..3144907) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type r : regulator; DNA-binding transcriptional repressor 3144907 ascG 7156757 ascG Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002413727.1 3143894 R 585056 CDS YP_002413728.1 218706209 7155808 3145164..3146621 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC 3146621 ascF 7155808 ascF Escherichia coli UMN026 PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC YP_002413728.1 3145164 D 585056 CDS YP_002413729.1 218706210 7155807 3146630..3148054 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type e : enzyme; cryptic 6-phospho-beta-glucosidase 3148054 ascB 7155807 ascB Escherichia coli UMN026 cryptic 6-phospho-beta-glucosidase YP_002413729.1 3146630 D 585056 CDS YP_002413730.1 218706211 7155806 complement(3148212..3148682) 1 NC_011751.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 3148682 hycI 7155806 hycI Escherichia coli UMN026 hydrogenase 3 maturation protease YP_002413730.1 3148212 R 585056 CDS YP_002413731.1 218706212 7156756 complement(3148675..3149085) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor; protein required for maturation of hydrogenase 3 3149085 hycH 7156756 hycH Escherichia coli UMN026 protein required for maturation of hydrogenase 3 YP_002413731.1 3148675 R 585056 CDS YP_002413732.1 218706213 7156755 complement(3149082..3149849) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme; hydrogenase 3 and formate hydrogenase complex, HycG subunit 3149849 hycG 7156755 hycG Escherichia coli UMN026 hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_002413732.1 3149082 R 585056 CDS YP_002413733.1 218706214 7156754 complement(3149849..3150391) 1 NC_011751.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 3150391 hycF 7156754 hycF Escherichia coli UMN026 formate hydrogenlyase complex iron-sulfur subunit YP_002413733.1 3149849 R 585056 CDS YP_002413734.1 218706215 7156753 complement(3150401..3152110) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme; hydrogenase 3, large subunit 3152110 hycE 7156753 hycE Escherichia coli UMN026 hydrogenase 3, large subunit YP_002413734.1 3150401 R 585056 CDS YP_002413735.1 218706216 7156752 complement(3152128..3153051) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component; hydrogenase 3, membrane subunit 3153051 hycD 7156752 hycD Escherichia coli UMN026 hydrogenase 3, membrane subunit YP_002413735.1 3152128 R 585056 CDS YP_002413736.1 218706217 7156751 complement(3153054..3154880) 1 NC_011751.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 3154880 hycC 7156751 hycC Escherichia coli UMN026 formate hydrogenlyase subunit 3 YP_002413736.1 3153054 R 585056 CDS YP_002413737.1 218706218 7156750 complement(3154877..3155488) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier; hydrogenase 3, Fe-S subunit 3155488 hycB 7156750 hycB Escherichia coli UMN026 hydrogenase 3, Fe-S subunit YP_002413737.1 3154877 R 585056 CDS YP_002413738.1 218706219 7156749 complement(3155613..3156074) 1 NC_011751.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 3156074 hycA 7156749 hycA Escherichia coli UMN026 formate hydrogenlyase regulatory protein HycA YP_002413738.1 3155613 R 585056 CDS YP_002413739.1 218706220 7156748 3156286..3156636 1 NC_011751.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3156636 hypA 7156748 hypA Escherichia coli UMN026 hydrogenase nickel incorporation protein YP_002413739.1 3156286 D 585056 CDS YP_002413740.1 218706221 7156770 3156640..3157512 1 NC_011751.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3157512 hypB 7156770 hypB Escherichia coli UMN026 hydrogenase nickel incorporation protein HypB YP_002413740.1 3156640 D 585056 CDS YP_002413741.1 218706222 7156771 3157503..3157775 1 NC_011751.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3157775 hypC 7156771 hypC Escherichia coli UMN026 hydrogenase assembly chaperone YP_002413741.1 3157503 D 585056 CDS YP_002413742.1 218706223 7156772 3157775..3158896 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor; protein required for maturation of hydrogenases 3158896 hypD 7156772 hypD Escherichia coli UMN026 protein required for maturation of hydrogenases YP_002413742.1 3157775 D 585056 CDS YP_002413743.1 218706224 7156773 3158935..3159903 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 3159903 hypE 7156773 hypE Escherichia coli UMN026 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_002413743.1 3158935 D 585056 CDS YP_002413744.1 218706225 7156774 3159977..3162055 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator; DNA-binding transcriptional activator 3162055 fhlA 7156774 fhlA Escherichia coli UMN026 DNA-binding transcriptional activator YP_002413744.1 3159977 D 585056 CDS YP_002413745.1 218706226 7156343 3162061..3162528 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative molybdenum-pterin-binding-protein 3162528 7156343 ECUMN_3055 Escherichia coli UMN026 putative molybdenum-pterin-binding-protein YP_002413745.1 3162061 D 585056 CDS YP_002413746.1 218706227 7155211 complement(3162567..3162911) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3162911 ygbA 7155211 ygbA Escherichia coli UMN026 hypothetical protein YP_002413746.1 3162567 R 585056 CDS YP_002413747.1 218706228 7158999 3163198..3165759 1 NC_011751.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3165759 mutS 7158999 mutS Escherichia coli UMN026 DNA mismatch repair protein MutS YP_002413747.1 3163198 D 585056 CDS YP_002413748.1 218706229 7157214 3165864..3166727 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3166727 7157214 ECUMN_3058 Escherichia coli UMN026 hypothetical protein YP_002413748.1 3165864 D 585056 CDS YP_002413749.1 218706230 7155212 3166740..3167408 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme; serine/threonine-specific protein phosphatase 2 3167408 pphB 7155212 pphB Escherichia coli UMN026 serine/threonine-specific protein phosphatase 2 YP_002413749.1 3166740 D 585056 CDS YP_002413750.1 218706231 7157504 complement(3167450..3167686) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; non-oxidative reversible hydroxyarylic acid decarboxylase 3167686 7157504 ECUMN_3060 Escherichia coli UMN026 non-oxidative reversible hydroxyarylic acid decarboxylase YP_002413750.1 3167450 R 585056 CDS YP_002413751.1 218706232 7155213 complement(3167697..3169124) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; putative non-oxidative hydroxyarylic acid decarboxylase 3169124 7155213 ECUMN_3061 Escherichia coli UMN026 putative non-oxidative hydroxyarylic acid decarboxylase YP_002413751.1 3167697 R 585056 CDS YP_002413752.1 218706233 7155214 complement(3169124..3169717) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; non-oxidative reversible hydroxyarylic acid decarboxylase 3169717 7155214 ECUMN_3062 Escherichia coli UMN026 non-oxidative reversible hydroxyarylic acid decarboxylase YP_002413752.1 3169124 R 585056 CDS YP_002413753.1 218706234 7155215 3169831..3170271 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15731069; Product type r : regulator; transcriptional regulator hosA 3170271 7155215 ECUMN_3063 Escherichia coli UMN026 transcriptional regulator hosA YP_002413753.1 3169831 D 585056 CDS YP_002413754.1 218706235 7155216 complement(3170392..3171384) 1 NC_011751.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3171384 rpoS 7155216 rpoS Escherichia coli UMN026 RNA polymerase sigma factor RpoS YP_002413754.1 3170392 R 585056 CDS YP_002413755.1 218706236 7157764 complement(3171447..3172586) 1 NC_011751.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3172586 nlpD 7157764 nlpD Escherichia coli UMN026 lipoprotein NlpD YP_002413755.1 3171447 R 585056 CDS YP_002413756.1 218706237 7157288 complement(3172726..3173352) 1 NC_011751.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3173352 pcm 7157288 pcm Escherichia coli UMN026 protein-L-isoaspartate O-methyltransferase YP_002413756.1 3172726 R 585056 CDS YP_002413757.1 218706238 7157397 complement(3173346..3174107) 1 NC_011751.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3174107 surE 7157397 surE Escherichia coli UMN026 stationary phase survival protein SurE YP_002413757.1 3173346 R 585056 CDS YP_002413758.1 218706239 7158014 complement(3174088..3175137) 1 NC_011751.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3175137 truD 7158014 truD Escherichia coli UMN026 tRNA pseudouridine synthase D YP_002413758.1 3174088 R 585056 CDS YP_002413759.1 218706240 7158128 complement(3175134..3175613) 1 NC_011751.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3175613 ispF 7158128 ispF Escherichia coli UMN026 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002413759.1 3175134 R 585056 CDS YP_002413760.1 218706241 7156866 complement(3175613..3176323) 1 NC_011751.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3176323 ispD 7156866 ispD Escherichia coli UMN026 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002413760.1 3175613 R 585056 CDS YP_002413761.1 218706242 7156864 complement(3176342..3176653) 1 NC_011751.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3176653 ftsB 7156864 ftsB Escherichia coli UMN026 cell division protein FtsB YP_002413761.1 3176342 R 585056 CDS YP_002413762.1 218706243 7156457 complement(3176847..3177170) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3177170 ygbE 7156457 ygbE Escherichia coli UMN026 hypothetical protein YP_002413762.1 3176847 R 585056 CDS YP_002413763.1 218706244 7159000 complement(3177220..3177825) 1 NC_011751.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3177825 cysC 7159000 cysC Escherichia coli UMN026 adenylylsulfate kinase YP_002413763.1 3177220 R 585056 CDS YP_002413764.1 218706245 7156080 complement(3177825..3179252) 1 NC_011751.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3179252 cysN 7156080 cysN Escherichia coli UMN026 sulfate adenylyltransferase subunit 1 YP_002413764.1 3177825 R 585056 CDS YP_002413765.1 218706246 7156089 complement(3179254..3180162) 1 NC_011751.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3180162 cysD 7156089 cysD Escherichia coli UMN026 sulfate adenylyltransferase subunit 2 YP_002413765.1 3179254 R 585056 CDS YP_002413766.1 218706247 7156081 3180414..3181451 1 NC_011751.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 3181451 iap 7156081 iap Escherichia coli UMN026 alkaline phosphatase isozyme conversion aminopeptidase YP_002413766.1 3180414 D 585056 CDS YP_002413769.1 218706250 7155218 complement(3182695..3182988) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3182988 ygbF 7155218 ygbF Escherichia coli UMN026 hypothetical protein YP_002413769.1 3182695 R 585056 CDS YP_002413770.1 218706251 7159003 complement(3183905..3184693) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3184693 7159003 ECUMN_3083 Escherichia coli UMN026 hypothetical protein YP_002413770.1 3183905 R 585056 CDS YP_002413771.1 218706252 7155219 complement(3184537..3185283) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3185283 7155219 ECUMN_3084 Escherichia coli UMN026 hypothetical protein YP_002413771.1 3184537 R 585056 CDS YP_002413772.1 218706253 7155220 complement(3185294..3186349) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3186349 7155220 ECUMN_3085 Escherichia coli UMN026 hypothetical protein YP_002413772.1 3185294 R 585056 CDS YP_002413773.1 218706254 7155221 complement(3186364..3186900) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3186900 7155221 ECUMN_3086 Escherichia coli UMN026 hypothetical protein YP_002413773.1 3186364 R 585056 CDS YP_002413774.1 218706255 7155222 complement(3186897..3188465) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3188465 7155222 ECUMN_3087 Escherichia coli UMN026 hypothetical protein YP_002413774.1 3186897 R 585056 CDS YP_002413775.1 218706256 7155223 complement(3188557..3191256) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3191256 7155223 ECUMN_3088 Escherichia coli UMN026 hypothetical protein YP_002413775.1 3188557 R 585056 CDS YP_002413776.1 218706257 7155224 complement(3191451..3191603) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : putative membrane component; small toxic peptide 3191603 7155224 ECUMN_3089 Escherichia coli UMN026 small toxic peptide YP_002413776.1 3191451 R 585056 CDS YP_002413777.1 218706258 7155225 complement(3191868..3192602) 1 NC_011751.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 3192602 cysH 7155225 cysH Escherichia coli UMN026 phosphoadenosine phosphosulfate reductase YP_002413777.1 3191868 R 585056 CDS YP_002413778.1 218706259 7156084 complement(3192676..3194388) 1 NC_011751.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3194388 cysI 7156084 cysI Escherichia coli UMN026 sulfite reductase subunit beta YP_002413778.1 3192676 R 585056 CDS YP_002413779.1 218706260 7156085 complement(3194388..3196187) 1 NC_011751.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3196187 cysJ 7156085 cysJ Escherichia coli UMN026 sulfite reductase subunit alpha YP_002413779.1 3194388 R 585056 CDS YP_002413780.1 218706261 7156086 3196503..3196868 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme; 6-pyruvoyl tetrahydrobiopterin synthase 3196868 ygcM 7156086 ygcM Escherichia coli UMN026 6-pyruvoyl tetrahydrobiopterin synthase YP_002413780.1 3196503 D 585056 CDS YP_002413781.1 218706262 7159007 3196946..3198217 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 3198217 ygcN 7159007 ygcN Escherichia coli UMN026 putative oxidoreductase YP_002413781.1 3196946 D 585056 CDS YP_002413782.1 218706263 7159008 3198208..3198468 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative 4Fe-4S cluster-containing protein 3198468 ygcO 7159008 ygcO Escherichia coli UMN026 putative 4Fe-4S cluster-containing protein YP_002413782.1 3198208 D 585056 CDS YP_002413783.1 218706264 7159009 3198485..3199060 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative anti-terminator regulatory protein 3199060 ygcP 7159009 ygcP Escherichia coli UMN026 putative anti-terminator regulatory protein YP_002413783.1 3198485 D 585056 CDS YP_002413784.1 218706265 7159010 complement(3199207..3200067) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative flavoprotein 3200067 ygcQ 7159010 ygcQ Escherichia coli UMN026 putative flavoprotein YP_002413784.1 3199207 R 585056 CDS YP_002413785.1 218706266 7159011 complement(3200064..3200843) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative flavoprotein 3200843 ygcR 7159011 ygcR Escherichia coli UMN026 putative flavoprotein YP_002413785.1 3200064 R 585056 CDS YP_002413786.1 218706267 7159012 complement(3200821..3202158) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3202158 ygcS 7159012 ygcS Escherichia coli UMN026 putative transporter YP_002413786.1 3200821 R 585056 CDS YP_002413787.1 218706268 7159013 complement(3202252..3203706) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative FAD containing dehydrogenase 3203706 ygcU 7159013 ygcU Escherichia coli UMN026 putative FAD containing dehydrogenase YP_002413787.1 3202252 R 585056 CDS YP_002413788.1 218706269 7159014 complement(3203776..3204561) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative deoxygluconate dehydrogenase 3204561 ygcW 7159014 ygcW Escherichia coli UMN026 putative deoxygluconate dehydrogenase YP_002413788.1 3203776 R 585056 CDS YP_002413789.1 218706270 7159015 3204880..3206157 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3206157 yqcE 7159015 yqcE Escherichia coli UMN026 putative transporter YP_002413789.1 3204880 D 585056 CDS YP_002413790.1 218706271 7159600 3206184..3207662 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative kinase 3207662 ygcE 7159600 ygcE Escherichia coli UMN026 putative kinase YP_002413790.1 3206184 D 585056 CDS YP_002413791.1 218706272 7159004 complement(3209218..3209889) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3209889 ygcF 7159004 ygcF Escherichia coli UMN026 hypothetical protein YP_002413791.1 3209218 R 585056 CDS YP_002413792.1 218706273 7159005 3210062..3210664 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3210664 7159005 ECUMN_3105 Escherichia coli UMN026 hypothetical protein YP_002413792.1 3210062 D 585056 CDS YP_002413793.1 218706274 7155226 3210648..3211571 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3211571 ygcG 7155226 ygcG Escherichia coli UMN026 hypothetical protein YP_002413793.1 3210648 D 585056 CDS YP_002413794.1 218706275 7159006 3211586..3212734 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3212734 7159006 ECUMN_3107 Escherichia coli UMN026 hypothetical protein YP_002413794.1 3211586 D 585056 CDS YP_002413795.1 218706276 7155227 3212728..3213645 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3213645 7155227 ECUMN_3109 Escherichia coli UMN026 hypothetical protein YP_002413795.1 3212728 D 585056 CDS YP_002413796.1 218706277 7155228 complement(3213705..3215003) 1 NC_011751.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3215003 eno 7155228 eno Escherichia coli UMN026 phosphopyruvate hydratase YP_002413796.1 3213705 R 585056 CDS YP_002413797.1 218706278 7156247 complement(3215090..3216727) 1 NC_011751.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3216727 pyrG 7156247 pyrG Escherichia coli UMN026 CTP synthetase YP_002413797.1 3215090 R 585056 CDS YP_002413798.1 218706279 7157602 complement(3216955..3217746) 1 NC_011751.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3217746 mazG 7157602 mazG Escherichia coli UMN026 nucleoside triphosphate pyrophosphohydrolase YP_002413798.1 3216955 R 585056 CDS YP_002413799.1 218706280 7157064 complement(3217842..3220076) 1 NC_011751.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3220076 relA 7157064 relA Escherichia coli UMN026 GDP/GTP pyrophosphokinase YP_002413799.1 3217842 R 585056 CDS YP_002413800.1 218706281 7157649 complement(3220124..3221425) 1 NC_011751.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 3221425 rumA 7157649 rumA Escherichia coli UMN026 23S rRNA 5-methyluridine methyltransferase YP_002413800.1 3220124 R 585056 CDS YP_002413801.1 218706282 7157817 3221482..3224238 1 NC_011751.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3224238 barA 7157817 barA Escherichia coli UMN026 hybrid sensory histidine kinase BarA YP_002413801.1 3221482 D 585056 CDS YP_002413802.1 218706283 7155851 complement(3224469..3225809) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme; (D)-glucarate dehydratase 1 3225809 gudD 7155851 gudD Escherichia coli UMN026 (D)-glucarate dehydratase 1 YP_002413802.1 3224469 R 585056 CDS YP_002413803.1 218706284 7156626 complement(3225830..3227170) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme; glucarate dehydratase 3227170 gudX 7156626 gudX Escherichia coli UMN026 glucarate dehydratase YP_002413803.1 3225830 R 585056 CDS YP_002413804.1 218706285 7156628 complement(3227172..3228524) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278; Product type pt : putative transporter; putative D-glucarate transporter 3228524 gudP 7156628 gudP Escherichia coli UMN026 putative D-glucarate transporter YP_002413804.1 3227172 R 585056 CDS YP_002413805.1 218706286 7156627 complement(3228999..3229448) 1 NC_011751.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 3229448 yqcA 7156627 yqcA Escherichia coli UMN026 flavodoxin YP_002413805.1 3228999 R 585056 CDS YP_002413806.1 218706287 7159598 complement(3229466..3230248) 1 NC_011751.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 3230248 truC 7159598 truC Escherichia coli UMN026 tRNA pseudouridine synthase C YP_002413806.1 3229466 R 585056 CDS YP_002413807.1 218706288 7158127 complement(3230248..3230577) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3230577 yqcC 7158127 yqcC Escherichia coli UMN026 hypothetical protein YP_002413807.1 3230248 R 585056 CDS YP_002413808.1 218706289 7156044 complement(3231199..3231744) 1 NC_011751.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 3231744 syd 7156044 syd Escherichia coli UMN026 SecY interacting protein Syd YP_002413808.1 3231199 R 585056 CDS YP_002413809.1 218706290 7158015 3231812..3232660 1 NC_011751.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3232660 queF 7158015 queF Escherichia coli UMN026 7-cyano-7-deazaguanine reductase YP_002413809.1 3231812 D 585056 CDS YP_002413810.1 218706291 7157614 3232772..3234136 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3234136 ygdH 7157614 ygdH Escherichia coli UMN026 hypothetical protein YP_002413810.1 3232772 D 585056 CDS YP_002413811.1 218706292 7159019 3234693..3235982 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : putative transporter; putative serine transporter 3235982 sdaC 7159019 sdaC Escherichia coli UMN026 putative serine transporter YP_002413811.1 3234693 D 585056 CDS YP_002413812.1 218706293 7157879 3236040..3237407 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme; L-serine deaminase II 3237407 sdaB 7157879 sdaB Escherichia coli UMN026 L-serine deaminase II YP_002413812.1 3236040 D 585056 CDS YP_002413813.1 218706294 7157878 3237428..3238273 1 NC_011751.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3238273 xni 7157878 xni Escherichia coli UMN026 exonuclease IX YP_002413813.1 3237428 D 585056 CDS YP_002413814.1 218706295 7156289 complement(3238378..3239529) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 89291720, 2553671, 2661535, 2664711, 8385012; Product type e : enzyme; L-1,2-propanediol oxidoreductase 3239529 fucO 7156289 fucO Escherichia coli UMN026 L-1,2-propanediol oxidoreductase YP_002413814.1 3238378 R 585056 CDS YP_002413815.1 218706296 7156472 complement(3239554..3240201) 1 NC_011751.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 3240201 fucA 7156472 fucA Escherichia coli UMN026 L-fuculose phosphate aldolase YP_002413815.1 3239554 R 585056 CDS YP_002413816.1 218706297 7156469 3240748..3242064 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2553671, 2664711, 7783647; Product type t : transporter; L-fucose transporter 3242064 fucP 7156469 fucP Escherichia coli UMN026 L-fucose transporter YP_002413816.1 3240748 D 585056 CDS YP_002413817.1 218706298 7156473 3242097..3243872 1 NC_011751.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3243872 fucI 7156473 fucI Escherichia coli UMN026 L-fucose isomerase YP_002413817.1 3242097 D 585056 CDS YP_002413818.1 218706299 7156470 3243951..3245399 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2664711, 13905785; Product type e : enzyme; L-fuculokinase 3245399 fucK 7156470 fucK Escherichia coli UMN026 L-fuculokinase YP_002413818.1 3243951 D 585056 CDS YP_002413819.1 218706300 7156471 3245401..3245823 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078, 12738765, 80049526, 2664711; Product type e : enzyme; L-fucose mutarotase 3245823 fucU 7156471 fucU Escherichia coli UMN026 L-fucose mutarotase YP_002413819.1 3245401 D 585056 CDS YP_002413820.1 218706301 7156475 3245881..3246612 1 NC_011751.1 regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3246612 fucR 7156475 fucR Escherichia coli UMN026 DNA-binding transcriptional activator FucR YP_002413820.1 3245881 D 585056 CDS YP_002413821.1 218706302 7156474 complement(3246656..3247756) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : putative enzyme; putative RNA 2'-O-ribose methyltransferase 3247756 ygdE 7156474 ygdE Escherichia coli UMN026 putative RNA 2'-O-ribose methyltransferase YP_002413821.1 3246656 R 585056 CDS YP_002413822.1 218706303 7159018 complement(3247749..3248144) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : putative membrane component; hypothetical protein 3248144 ygdD 7159018 ygdD Escherichia coli UMN026 hypothetical protein YP_002413822.1 3247749 R 585056 CDS YP_002413823.1 218706304 7159017 complement(3248163..3249080) 1 NC_011751.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 3249080 gcvA 7159017 gcvA Escherichia coli UMN026 DNA-binding transcriptional activator GcvA YP_002413823.1 3248163 R 585056 CDS YP_002413824.1 218706305 7156521 3249375..3249692 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3249692 7156521 ECUMN_3138 Escherichia coli UMN026 hypothetical protein YP_002413824.1 3249375 D 585056 CDS YP_002413825.1 218706306 7155229 complement(3249432..3249659) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3249659 ygdI 7155229 ygdI Escherichia coli UMN026 hypothetical protein YP_002413825.1 3249432 R 585056 CDS YP_002413826.1 218706307 7159020 3249851..3251056 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme; cysteine sulfinate desulfinase 3251056 csdA 7159020 csdA Escherichia coli UMN026 cysteine sulfinate desulfinase YP_002413826.1 3249851 D 585056 CDS YP_002413827.1 218706308 7156024 3251056..3251499 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Fe-S metabolism protein (sufE-like) 3251499 ygdK 7156024 ygdK Escherichia coli UMN026 putative Fe-S metabolism protein (sufE-like) YP_002413827.1 3251056 D 585056 CDS YP_002413828.1 218706309 7159021 complement(3251550..3252356) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3252356 ygdL 7159021 ygdL Escherichia coli UMN026 hypothetical protein YP_002413828.1 3251550 R 585056 CDS YP_002413829.1 218706310 7159022 complement(3252595..3253692) 1 NC_011751.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 3253692 mltA 7159022 mltA Escherichia coli UMN026 murein transglycosylase A YP_002413829.1 3252595 R 585056 CDS YP_002413830.1 218706311 7155586 complement(3254380..3255633) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase 3255633 amiC 7155586 amiC Escherichia coli UMN026 N-acetylmuramoyl-L-alanine amidase YP_002413830.1 3254380 R 585056 CDS YP_002413831.1 218706312 7155735 3255865..3257196 1 NC_011751.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3257196 argA 7155735 argA Escherichia coli UMN026 N-acetylglutamate synthase YP_002413831.1 3255865 D 585056 CDS YP_002413832.1 218706313 7155768 complement(3257258..3259084) 1 NC_011751.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 3259084 recD 7155768 recD Escherichia coli UMN026 exonuclease V subunit alpha YP_002413832.1 3257258 R 585056 CDS YP_002413833.1 218706314 7157640 complement(3259084..3262626) 1 NC_011751.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 3262626 recB 7157640 recB Escherichia coli UMN026 exonuclease V subunit beta YP_002413833.1 3259084 R 585056 CDS YP_002413834.1 218706315 7157638 complement(3262619..3265507) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme; protease III 3265507 ptr 7157638 ptr Escherichia coli UMN026 protease III YP_002413834.1 3262619 R 585056 CDS YP_002413835.1 218706316 7157563 complement(3265683..3269051) 1 NC_011751.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 3269051 recC 7157563 recC Escherichia coli UMN026 exonuclease V subunit gamma YP_002413835.1 3265683 R 585056 CDS YP_002413836.1 218706317 7157639 complement(3269064..3269387) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein 3269387 ppdC 7157639 ppdC Escherichia coli UMN026 hypothetical protein YP_002413836.1 3269064 R 585056 CDS YP_002413837.1 218706318 7157501 complement(3269372..3269779) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3269779 ygdB 7157501 ygdB Escherichia coli UMN026 hypothetical protein YP_002413837.1 3269372 R 585056 CDS YP_002413838.1 218706319 7159016 complement(3269776..3270339) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein 3270339 ppdB 7159016 ppdB Escherichia coli UMN026 hypothetical protein YP_002413838.1 3269776 R 585056 CDS YP_002413839.1 218706320 7157500 complement(3270330..3270800) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme; hypothetical protein 3270800 ppdA 7157500 ppdA Escherichia coli UMN026 hypothetical protein YP_002413839.1 3270330 R 585056 CDS YP_002413840.1 218706321 7157499 complement(3270985..3271779) 1 NC_011751.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 3271779 thyA 7157499 thyA Escherichia coli UMN026 thymidylate synthase YP_002413840.1 3270985 R 585056 CDS YP_002413841.1 218706322 7158069 complement(3271786..3272661) 1 NC_011751.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3272661 lgt 7158069 lgt Escherichia coli UMN026 prolipoprotein diacylglyceryl transferase YP_002413841.1 3271786 R 585056 CDS YP_002413842.1 218706323 7156977 complement(3272812..3275058) 1 NC_011751.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein 3275058 ptsP 7156977 ptsP Escherichia coli UMN026 bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein YP_002413842.1 3272812 R 585056 CDS YP_002413843.1 218706324 7157571 complement(3275071..3275601) 1 NC_011751.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 3275601 nudH 7157571 nudH Escherichia coli UMN026 dinucleoside polyphosphate hydrolase YP_002413843.1 3275071 R 585056 CDS YP_002413844.1 218706325 7157322 3276286..3276975 1 NC_011751.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3276975 mutH 7157322 mutH Escherichia coli UMN026 DNA mismatch repair protein YP_002413844.1 3276286 D 585056 CDS YP_002413845.1 218706326 7157211 3277044..3277757 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3277757 ygdQ 7157211 ygdQ Escherichia coli UMN026 hypothetical protein YP_002413845.1 3277044 D 585056 CDS YP_002413846.1 218706327 7159023 3277895..3278113 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3278113 ygdR 7159023 ygdR Escherichia coli UMN026 hypothetical protein YP_002413846.1 3277895 D 585056 CDS YP_002413847.1 218706328 7159024 3278221..3279261 1 NC_011751.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 3279261 tas 7159024 tas Escherichia coli UMN026 putative aldo-keto reductase YP_002413847.1 3278221 D 585056 CDS YP_002413848.1 218706329 7158024 complement(3279293..3280486) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : putative membrane component; lysophospholipid transporter LplT 3280486 ygeD 7158024 ygeD Escherichia coli UMN026 lysophospholipid transporter LplT YP_002413848.1 3279293 R 585056 CDS YP_002413849.1 218706330 7159025 complement(3280479..3282638) 1 NC_011751.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 3282638 aas 7159025 aas Escherichia coli UMN026 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_002413849.1 3280479 R 585056 CDS YP_002413850.1 218706331 7157354 3283224..3284255 1 NC_011751.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3284255 galR 7157354 galR Escherichia coli UMN026 DNA-binding transcriptional regulator GalR YP_002413850.1 3283224 D 585056 CDS YP_002413851.1 218706332 7156498 complement(3284262..3285524) 1 NC_011751.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 3285524 lysA 7156498 lysA Escherichia coli UMN026 diaminopimelate decarboxylase YP_002413851.1 3284262 R 585056 CDS YP_002413852.1 218706333 7157029 3285646..3286581 1 NC_011751.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3286581 lysR 7157029 lysR Escherichia coli UMN026 DNA-binding transcriptional regulator LysR YP_002413852.1 3285646 D 585056 CDS YP_002413853.1 218706334 7157032 complement(3286568..3287635) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative racemase 3287635 7157032 ECUMN_3168 Escherichia coli UMN026 putative racemase YP_002413853.1 3286568 R 585056 CDS YP_002413854.1 218706335 7155230 complement(3287389..3288807) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7030324, 90239116, 91154204, 2836407, 3543693, 6319708; Product type t : transporter; arabinose transporter 3288807 araE 7155230 araE Escherichia coli UMN026 arabinose transporter YP_002413854.1 3287389 R 585056 CDS YP_002413855.1 218706336 7155761 complement(3289122..3289883) 1 NC_011751.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 3289883 kduD 7155761 kduD Escherichia coli UMN026 2-deoxy-D-gluconate 3-dehydrogenase YP_002413855.1 3289122 R 585056 CDS YP_002413856.1 218706337 7156900 complement(3289913..3290749) 1 NC_011751.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 3290749 kduI 7156900 kduI Escherichia coli UMN026 5-keto-4-deoxyuronate isomerase YP_002413856.1 3289913 R 585056 CDS YP_002413857.1 218706338 7156901 complement(3291037..3292218) 1 NC_011751.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 3292218 yqeF 7156901 yqeF Escherichia coli UMN026 acetyl-CoA acetyltransferase YP_002413857.1 3291037 R 585056 CDS YP_002413858.1 218706339 7159604 3292474..3293703 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3293703 yqeG 7159604 yqeG Escherichia coli UMN026 putative transporter YP_002413858.1 3292474 D 585056 CDS YP_002413859.1 218706340 7159605 3294163..3294795 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3294795 yqeH 7159605 yqeH Escherichia coli UMN026 hypothetical protein YP_002413859.1 3294163 D 585056 CDS YP_002413860.1 218706341 7159606 3295129..3295938 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3295938 yqeI 7159606 yqeI Escherichia coli UMN026 putative transcriptional regulator YP_002413860.1 3295129 D 585056 CDS YP_002413861.1 218706342 7159607 3295931..3296413 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3296413 yqeJ 7159607 yqeJ Escherichia coli UMN026 hypothetical protein YP_002413861.1 3295931 D 585056 CDS YP_002413862.1 218706343 7159608 complement(3296562..3296987) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3296987 yqeK 7159608 yqeK Escherichia coli UMN026 hypothetical protein YP_002413862.1 3296562 R 585056 CDS YP_002413863.1 218706344 7159609 complement(3297027..3297176) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3297176 7159609 ECUMN_3179 Escherichia coli UMN026 hypothetical protein YP_002413863.1 3297027 R 585056 CDS YP_002413864.1 218706345 7155231 3297417..3297908 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3297908 ygeF 7155231 ygeF Escherichia coli UMN026 hypothetical protein YP_002413864.1 3297417 D 585056 CDS YP_002413865.1 218706346 7159026 3298134..3298625 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative chaperone 3298625 ygeG 7159026 ygeG Escherichia coli UMN026 putative chaperone YP_002413865.1 3298134 D 585056 CDS YP_002413866.1 218706347 7159027 3298960..3300336 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15150243; Product type pr : putative regulator; transcriptional regulator 3300336 ygeH 7159027 ygeH Escherichia coli UMN026 transcriptional regulator YP_002413866.1 3298960 D 585056 CDS YP_002413867.1 218706348 7159028 3300462..3300722 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3300722 ygeI 7159028 ygeI Escherichia coli UMN026 hypothetical protein YP_002413867.1 3300462 D 585056 CDS YP_002413868.1 218706349 7159029 3300806..3301309 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative peptidoglycan-binding-like protein 3301309 7159029 ECUMN_3184 Escherichia coli UMN026 putative peptidoglycan-binding-like protein YP_002413868.1 3300806 D 585056 CDS YP_002413869.1 218706350 7155232 complement(3301328..3301960) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3301960 7155232 ECUMN_3185 Escherichia coli UMN026 hypothetical protein YP_002413869.1 3301328 R 585056 CDS YP_002413870.1 218706351 7155233 complement(3302183..3302953) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3302953 7155233 ECUMN_3186 Escherichia coli UMN026 hypothetical protein YP_002413870.1 3302183 R 585056 CDS YP_002413871.1 218706352 7155234 complement(3302832..3303413) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; hypothetical protein 3303413 7155234 ECUMN_3187 Escherichia coli UMN026 hypothetical protein YP_002413871.1 3302832 R 585056 CDS YP_002413872.1 218706353 7155235 complement(3303429..3304163) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component; putative type III secretion system lipoprotein EprK 3304163 eprK 7155235 eprK Escherichia coli UMN026 putative type III secretion system lipoprotein EprK YP_002413872.1 3303429 R 585056 CDS YP_002413873.1 218706354 7156261 complement(3304160..3304492) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative type III secretion apparatus protein 3304492 7156261 ECUMN_3189 Escherichia coli UMN026 putative type III secretion apparatus protein YP_002413873.1 3304160 R 585056 CDS YP_002413874.1 218706355 7155236 complement(3304512..3304751) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16501225; Product type f : factor; type III secretion system needle protein 3304751 prgI 7155236 prgI Escherichia coli UMN026 type III secretion system needle protein YP_002413874.1 3304512 R 585056 CDS YP_002413875.1 218706356 7157521 complement(3304765..3305955) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative type III secretion EprH protein 3305955 eprH 7157521 eprH Escherichia coli UMN026 putative type III secretion EprH protein YP_002413875.1 3304765 R 585056 CDS YP_002413876.1 218706357 7156260 3306205..3306705 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; putative response regulator 3306705 7156260 ECUMN_3192 Escherichia coli UMN026 putative response regulator YP_002413876.1 3306205 D 585056 CDS YP_002413877.1 218706358 7155237 3306707..3307000 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12791847; hypothetical protein 3307000 7155237 ECUMN_3193 Escherichia coli UMN026 hypothetical protein YP_002413877.1 3306707 D 585056 CDS YP_002413878.1 218706359 7155238 complement(3307071..3308183) 1 NC_011751.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; surface presentation of antigens protein SpaS 3308183 spaS 7155238 spaS Escherichia coli UMN026 surface presentation of antigens protein SpaS YP_002413878.1 3307071 R 585056 CDS YP_002413879.1 218706360 7157956 complement(3308192..3308959) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component; putative type III secretion protein EpaR 3308959 7157956 ECUMN_3195 Escherichia coli UMN026 putative type III secretion protein EpaR YP_002413879.1 3308192 R 585056 CDS YP_002413880.1 218706361 7155239 complement(3308961..3309308) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component; surface presentation of antigens protein 3309308 spaQ 7155239 spaQ Escherichia coli UMN026 surface presentation of antigens protein YP_002413880.1 3308961 R 585056 CDS YP_002413881.1 218706362 7157955 complement(3309232..3309897) 1 NC_011751.1 part of a type III secretory system probably involved in invasion into eukaryotic cells; surface presentation of antigens protein SpaP 3309897 spaP 7157955 spaP Escherichia coli UMN026 surface presentation of antigens protein SpaP YP_002413881.1 3309232 R 585056 CDS YP_002413882.1 218706363 7155240 complement(3309887..3310834) 1 NC_011751.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells; surface presentation of antigens protein SpaO 3310834 epaO 7155240 epaO Escherichia coli UMN026 surface presentation of antigens protein SpaO YP_002413882.1 3309887 R 585056 CDS YP_002413883.1 218706364 7156258 complement(3310834..3311709) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; type III secretion protein 3311709 eivJ 7156258 eivJ Escherichia coli UMN026 type III secretion protein YP_002413883.1 3310834 R 585056 CDS YP_002413884.1 218706365 7156233 complement(3311687..3312154) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pt : putative transporter; type III secretion apparatus protein 3312154 7156233 ECUMN_3200 Escherichia coli UMN026 type III secretion apparatus protein YP_002413884.1 3311687 R 585056 CDS YP_002413885.1 218706366 7155241 complement(3312135..3313454) 1 NC_011751.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase; ATP synthase SpaL 3313454 7155241 ECUMN_3201 Escherichia coli UMN026 ATP synthase SpaL YP_002413885.1 3312135 R 585056 CDS YP_002413886.1 218706367 7155242 complement(3313459..3315519) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1624429; Product type t : transporter; invasion protein 3315519 invA 7155242 invA Escherichia coli UMN026 invasion protein YP_002413886.1 3313459 R 585056 CDS YP_002413887.1 218706368 7156846 complement(3315512..3316681) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type f : factor; hypothetical protein 3316681 7156846 ECUMN_3203 Escherichia coli UMN026 hypothetical protein YP_002413887.1 3315512 R 585056 CDS YP_002413888.1 218706369 7155243 complement(3316662..3318365) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; protein invG 3318365 7155243 ECUMN_3204 Escherichia coli UMN026 protein invG YP_002413888.1 3316662 R 585056 CDS YP_002413889.1 218706370 7155244 complement(3318362..3319111) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pr : putative regulator; Invasion protein invF 3319111 7155244 ECUMN_3205 Escherichia coli UMN026 Invasion protein invF YP_002413889.1 3318362 R 585056 CDS YP_002413890.1 218706371 7155245 complement(3319702..3321354) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3321354 7155245 ECUMN_3207 Escherichia coli UMN026 hypothetical protein YP_002413890.1 3319702 R 585056 CDS YP_002413891.1 218706372 7155623 complement(3321697..3322473) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15150243; Product type r : regulator; Tetratricopeptide repeat transcriptional regulator 3322473 ygeR 7155623 ygeR Escherichia coli UMN026 Tetratricopeptide repeat transcriptional regulator YP_002413891.1 3321697 R 585056 CDS YP_002413892.1 218706373 7159030 3322904..3325162 1 NC_011751.1 putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3325162 xdhA 7159030 xdhA Escherichia coli UMN026 xanthine dehydrogenase subunit XdhA YP_002413892.1 3322904 D 585056 CDS YP_002413893.1 218706374 7158242 3325173..3326051 1 NC_011751.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3326051 xdhB 7158242 xdhB Escherichia coli UMN026 xanthine dehydrogenase subunit XdhB YP_002413893.1 3325173 D 585056 CDS YP_002413894.1 218706375 7158243 3326048..3326527 1 NC_011751.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3326527 xdhC 7158243 xdhC Escherichia coli UMN026 xanthine dehydrogenase subunit XdhC YP_002413894.1 3326048 D 585056 CDS YP_002413895.1 218706376 7158244 complement(3326567..3328345) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3328345 ygeV 7158244 ygeV Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413895.1 3326567 R 585056 CDS YP_002413896.1 218706377 7159031 3328822..3330012 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; aspartate/ornithine carbamoyltransferase family protein 3330012 ygeW 7159031 ygeW Escherichia coli UMN026 aspartate/ornithine carbamoyltransferase family protein YP_002413896.1 3328822 D 585056 CDS YP_002413897.1 218706378 7159032 3330070..3331266 1 NC_011751.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3331266 ygeX 7159032 ygeX Escherichia coli UMN026 diaminopropionate ammonia-lyase YP_002413897.1 3330070 D 585056 CDS YP_002413898.1 218706379 7159033 3331324..3332535 1 NC_011751.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3332535 ygeY 7159033 ygeY Escherichia coli UMN026 peptidase YP_002413898.1 3331324 D 585056 CDS YP_002413899.1 218706380 7159034 3332588..3333973 1 NC_011751.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3333973 hyuA 7159034 hyuA Escherichia coli UMN026 phenylhydantoinase YP_002413899.1 3332588 D 585056 CDS YP_002413900.1 218706381 7156776 3334021..3334953 1 NC_011751.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3334953 yqeA 7156776 yqeA Escherichia coli UMN026 carbamate kinase YP_002413900.1 3334021 D 585056 CDS YP_002413901.1 218706382 7159601 complement(3335173..3336798) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3336798 yqeB 7159601 yqeB Escherichia coli UMN026 hypothetical protein YP_002413901.1 3335173 R 585056 CDS YP_002413902.1 218706383 7159602 complement(3336846..3337616) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3337616 yqeC 7159602 yqeC Escherichia coli UMN026 hypothetical protein YP_002413902.1 3336846 R 585056 CDS YP_002413903.1 218706384 7159603 3337719..3338297 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3338297 ygfJ 7159603 ygfJ Escherichia coli UMN026 hypothetical protein YP_002413903.1 3337719 D 585056 CDS YP_002413904.1 218706385 7159040 3338619..3341717 1 NC_011751.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 3341717 ygfK 7159040 ygfK Escherichia coli UMN026 putative selenate reductase subunit YgfK YP_002413904.1 3338619 D 585056 CDS YP_002413905.1 218706386 7159041 3341720..3343048 1 NC_011751.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 3343048 ssnA 7159041 ssnA Escherichia coli UMN026 putative chlorohydrolase/aminohydrolase YP_002413905.1 3341720 D 585056 CDS YP_002413906.1 218706387 7157985 3343099..3343878 1 NC_011751.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 3343878 ygfM 7157985 ygfM Escherichia coli UMN026 putative selenate reductase subunit YgfM YP_002413906.1 3343099 D 585056 CDS YP_002413907.1 218706388 7159042 3343875..3346745 1 NC_011751.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 3346745 xdhD 7159042 xdhD Escherichia coli UMN026 putative selenate reductase subunit YgfN YP_002413907.1 3343875 D 585056 CDS YP_002413908.1 218706389 7158245 3346910..3348310 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20372655, 98213740; Product type pt : putative transporter; putative transporter 3348310 ygfO 7158245 ygfO Escherichia coli UMN026 putative transporter YP_002413908.1 3346910 D 585056 CDS YP_002413909.1 218706390 7159043 3348325..3349644 1 NC_011751.1 Catalyzes the deamination of guanine; guanine deaminase 3349644 guaD 7159043 guaD Escherichia coli UMN026 guanine deaminase YP_002413909.1 3348325 D 585056 CDS YP_002413910.1 218706391 7156625 3349680..3351047 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3351047 ygfQ 7156625 ygfQ Escherichia coli UMN026 putative transporter YP_002413910.1 3349680 D 585056 CDS YP_002413911.1 218706392 7159044 complement(3351083..3351571) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative oxidoreductase 3351571 ygfS 7159044 ygfS Escherichia coli UMN026 putative oxidoreductase YP_002413911.1 3351083 R 585056 CDS YP_002413912.1 218706393 7159045 complement(3351571..3353490) 1 NC_011751.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit 3353490 ygfT 7159045 ygfT Escherichia coli UMN026 putative oxidoreductase Fe-S binding subunit YP_002413912.1 3351571 R 585056 CDS YP_002413913.1 218706394 7159046 3353926..3355374 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9098051; Product type t : transporter; transporter 3355374 ygfU 7159046 ygfU Escherichia coli UMN026 transporter YP_002413913.1 3353926 D 585056 CDS YP_002413914.1 218706395 7159047 3355624..3356172 1 NC_011751.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3356172 idi 7159047 idi Escherichia coli UMN026 isopentenyl-diphosphate delta-isomerase YP_002413914.1 3355624 D 585056 CDS YP_002413915.1 218706396 7156787 complement(3356215..3357732) 1 NC_011751.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 3357732 lysS 7156787 lysS Escherichia coli UMN026 lysyl-tRNA synthetase YP_002413915.1 3356215 R 585056 CDS YP_002413916.1 218706397 7157033 complement(join(3357742..3358764,3358766..3358840)) 1 NC_011751.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 3358840 prfB 7157033 prfB Escherichia coli UMN026 peptide chain release factor 2 YP_002413916.1 3357742 R 585056 CDS YP_002413917.1 218706398 7157518 complement(3358931..3360664) 1 NC_011751.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 3360664 recJ 7157518 recJ Escherichia coli UMN026 ssDNA exonuclease RecJ YP_002413917.1 3358931 R 585056 CDS YP_002413918.1 218706399 7157643 complement(3360670..3361380) 1 NC_011751.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 3361380 dsbC 7157643 dsbC Escherichia coli UMN026 thiol:disulfide interchange protein DsbC YP_002413918.1 3360670 R 585056 CDS YP_002413919.1 218706400 7156204 complement(3361405..3362301) 1 NC_011751.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 3362301 xerD 7156204 xerD Escherichia coli UMN026 site-specific tyrosine recombinase XerD YP_002413919.1 3361405 R 585056 CDS YP_002413920.1 218706401 7158247 3362413..3362934 1 NC_011751.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3362934 fldB 7158247 fldB Escherichia coli UMN026 flavodoxin FldB YP_002413920.1 3362413 D 585056 CDS YP_002413921.1 218706402 7156376 complement(3362974..3363381) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3363381 ygfX 7156376 ygfX Escherichia coli UMN026 hypothetical protein YP_002413921.1 3362974 R 585056 CDS YP_002413922.1 218706403 7159048 complement(3363362..3363628) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3363628 ygfY 7159048 ygfY Escherichia coli UMN026 hypothetical protein YP_002413922.1 3363362 R 585056 CDS YP_002413923.1 218706404 7159049 3363871..3364851 1 NC_011751.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 3364851 ygfZ 7159049 ygfZ Escherichia coli UMN026 putative global regulator YP_002413923.1 3363871 D 585056 CDS YP_002413924.1 218706405 7159050 complement(3364928..3365587) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative hemolysin, inner membrane subunit 3365587 yqfA 7159050 yqfA Escherichia coli UMN026 putative hemolysin, inner membrane subunit YP_002413924.1 3364928 R 585056 CDS YP_002413925.1 218706406 7159610 complement(3365751..3366062) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3366062 yqfB 7159610 yqfB Escherichia coli UMN026 hypothetical protein YP_002413925.1 3365751 R 585056 CDS YP_002413926.1 218706407 7159611 3366101..3367540 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme; 6-phospho-beta-glucosidase A 3367540 bglA 7159611 bglA Escherichia coli UMN026 6-phospho-beta-glucosidase A YP_002413926.1 3366101 D 585056 CDS YP_002413927.1 218706408 7155873 complement(3367706..3370579) 1 NC_011751.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 3370579 gcvP 7155873 gcvP Escherichia coli UMN026 glycine dehydrogenase YP_002413927.1 3367706 R 585056 CDS YP_002413928.1 218706409 7156523 complement(3370698..3371087) 1 NC_011751.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 3371087 gcvH 7156523 gcvH Escherichia coli UMN026 glycine cleavage system protein H YP_002413928.1 3370698 R 585056 CDS YP_002413929.1 218706410 7156522 complement(3371111..3372205) 1 NC_011751.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 3372205 gcvT 7156522 gcvT Escherichia coli UMN026 glycine cleavage system aminomethyltransferase T YP_002413929.1 3371111 R 585056 CDS YP_002413930.1 218706411 7156525 complement(3372653..3373855) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : putative enzyme; hypothetical protein 3373855 visC 7156525 visC Escherichia coli UMN026 hypothetical protein YP_002413930.1 3372653 R 585056 CDS YP_002413931.1 218706412 7158211 complement(3373878..3375056) 1 NC_011751.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 3375056 ubiH 7158211 ubiH Escherichia coli UMN026 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002413931.1 3373878 R 585056 CDS YP_002413932.1 218706413 7158159 complement(3375053..3376378) 1 NC_011751.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 3376378 pepP 7158159 pepP Escherichia coli UMN026 proline aminopeptidase P II YP_002413932.1 3375053 R 585056 CDS YP_002413933.1 218706414 7157415 complement(3376404..3376982) 1 NC_011751.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 3376982 ygfB 7157415 ygfB Escherichia coli UMN026 hypothetical protein YP_002413933.1 3376404 R 585056 CDS YP_002413934.1 218706415 7159036 3377150..3377479 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process; Z-ring-associated protein 3377479 zapA 7159036 zapA Escherichia coli UMN026 Z-ring-associated protein YP_002413934.1 3377150 D 585056 CDS YP_002413935.1 218706416 7157989 3377779..3378327 1 NC_011751.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 3378327 ygfA 7157989 ygfA Escherichia coli UMN026 putative ligase YP_002413935.1 3377779 D 585056 CDS YP_002413936.1 218706417 7157852 complement(3378716..3379948) 1 NC_011751.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 3379948 serA 7157852 serA Escherichia coli UMN026 D-3-phosphoglycerate dehydrogenase YP_002413936.1 3378716 R 585056 CDS YP_002413937.1 218706418 7157897 complement(3380204..3380863) 1 NC_011751.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 3380863 rpiA 7157897 rpiA Escherichia coli UMN026 ribose-5-phosphate isomerase A YP_002413937.1 3380204 R 585056 CDS YP_002413938.1 218706419 7157724 complement(3380919..3381815) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3381815 7157724 ECUMN_3256 Escherichia coli UMN026 hypothetical protein YP_002413938.1 3380919 R 585056 CDS YP_002413939.1 218706420 7155247 3381916..3382545 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; FMN-dependent NADH-azoreductase 3382545 7155247 ECUMN_3257 Escherichia coli UMN026 FMN-dependent NADH-azoreductase YP_002413939.1 3381916 D 585056 CDS YP_002413940.1 218706421 7155248 3382562..3382822 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3382822 7155248 ECUMN_3258 Escherichia coli UMN026 hypothetical protein YP_002413940.1 3382562 D 585056 CDS YP_002413941.1 218706422 7155249 3382884..3384209 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Flavodoxin oxidoreductase 3384209 7155249 ECUMN_3259 Escherichia coli UMN026 putative Flavodoxin oxidoreductase YP_002413941.1 3382884 D 585056 CDS YP_002413942.1 218706423 7155250 3384280..3385173 1 NC_011751.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3385173 argP 7155250 argP Escherichia coli UMN026 chromosome replication initiation inhibitor protein YP_002413942.1 3384280 D 585056 CDS YP_002413943.1 218706424 7155778 3385377..3387521 1 NC_011751.1 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 3387521 yliK 7155778 yliK Escherichia coli UMN026 methylmalonyl-CoA mutase YP_002413943.1 3385377 D 585056 CDS YP_002413944.1 218706425 7159472 3387514..3388509 1 NC_011751.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3388509 argK 7159472 argK Escherichia coli UMN026 arginine/ornithine transport system ATPase YP_002413944.1 3387514 D 585056 CDS YP_002413945.1 218706426 7155776 3388520..3389305 1 NC_011751.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3389305 ygfG 7155776 ygfG Escherichia coli UMN026 methylmalonyl-CoA decarboxylase YP_002413945.1 3388520 D 585056 CDS YP_002413946.1 218706427 7159037 3389329..3390807 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233703; Product type e : enzyme; propionyl-CoA:succinate-CoA transferase 3390807 ygfH 7159037 ygfH Escherichia coli UMN026 propionyl-CoA:succinate-CoA transferase YP_002413946.1 3389329 D 585056 CDS YP_002413947.1 218706428 7159038 complement(3390804..3391700) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3391700 ygfI 7159038 ygfI Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413947.1 3390804 R 585056 CDS YP_002413948.1 218706429 7159039 complement(3391868..3392608) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3392608 yggE 7159039 yggE Escherichia coli UMN026 hypothetical protein YP_002413948.1 3391868 R 585056 CDS YP_002413949.1 218706430 7159053 complement(3392701..3393336) 1 NC_011751.1 Involved in the export of arginine; arginine exporter protein 3393336 argO 7159053 argO Escherichia coli UMN026 arginine exporter protein YP_002413949.1 3392701 R 585056 CDS YP_002413950.1 218706431 7155777 3393452..3394495 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3394495 7155777 ECUMN_3268 Escherichia coli UMN026 hypothetical protein YP_002413950.1 3393452 D 585056 CDS YP_002413951.1 218706432 7155251 complement(3394537..3395412) 1 NC_011751.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 3395412 mscS 7155251 mscS Escherichia coli UMN026 mechanosensitive channel MscS YP_002413951.1 3394537 R 585056 CDS YP_002413952.1 218706433 7157186 complement(3395770..3396849) 1 NC_011751.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 3396849 fbaA 7157186 fbaA Escherichia coli UMN026 fructose-bisphosphate aldolase YP_002413952.1 3395770 R 585056 CDS YP_002413953.1 218706434 7156309 complement(3397063..3398226) 1 NC_011751.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3398226 pgk 7156309 pgk Escherichia coli UMN026 phosphoglycerate kinase YP_002413953.1 3397063 R 585056 CDS YP_002413954.1 218706435 7157427 complement(3398276..3399295) 1 NC_011751.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 3399295 epd 7157427 epd Escherichia coli UMN026 erythrose 4-phosphate dehydrogenase YP_002413954.1 3398276 R 585056 CDS YP_002413955.1 218706436 7156259 3399667..3400098 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3400098 7156259 ECUMN_3273 Escherichia coli UMN026 hypothetical protein YP_002413955.1 3399667 D 585056 CDS YP_002413956.1 218706437 7155252 3400022..3400699 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC-type transport system 3400699 7155252 ECUMN_3274 Escherichia coli UMN026 putative ABC-type transport system YP_002413956.1 3400022 D 585056 CDS YP_002413957.1 218706438 7155253 3400700..3401407 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC-type transport system 3401407 7155253 ECUMN_3275 Escherichia coli UMN026 putative ABC-type transport system YP_002413957.1 3400700 D 585056 CDS YP_002413958.1 218706439 7155254 3401389..3402072 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3402072 7155254 ECUMN_3276 Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002413958.1 3401389 D 585056 CDS YP_002413959.1 218706440 7155255 3402033..3402743 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3402743 7155255 ECUMN_3277 Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002413959.1 3402033 D 585056 CDS YP_002413960.1 218706441 7155256 complement(3402715..3403428) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative fructose transport system kinase 3403428 frcK 7155256 frcK Escherichia coli UMN026 putative fructose transport system kinase YP_002413960.1 3402715 R 585056 CDS YP_002413961.1 218706442 7159051 complement(3403425..3403934) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3403934 yggD 7159051 yggD Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002413961.1 3403425 R 585056 CDS YP_002413962.1 218706443 7159052 complement(3403956..3404921) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; fructose-1,6-bisphosphatase II-like protein 3404921 yggF 7159052 yggF Escherichia coli UMN026 fructose-1,6-bisphosphatase II-like protein YP_002413962.1 3403956 R 585056 CDS YP_002413963.1 218706444 7159054 complement(3404918..3406195) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative dehydrogenase 3406195 yggP 7159054 yggP Escherichia coli UMN026 putative dehydrogenase YP_002413963.1 3404918 R 585056 CDS YP_002413964.1 218706445 7159061 complement(3406210..3407598) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter; PTS system mannitol-specific transporter subunit IIBC 3407598 cmtA 7159061 cmtA Escherichia coli UMN026 PTS system mannitol-specific transporter subunit IIBC YP_002413964.1 3406210 R 585056 CDS YP_002413965.1 218706446 7155986 complement(3407626..3408069) 1 NC_011751.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA 3408069 cmtB 7155986 cmtB Escherichia coli UMN026 putative mannitol phosphotransferase subunit EIIA YP_002413965.1 3407626 R 585056 CDS YP_002413966.1 218706447 7155987 3408410..3409354 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative membrane protease 3409354 7155987 ECUMN_3284 Escherichia coli UMN026 putative membrane protease YP_002413966.1 3408410 D 585056 CDS YP_002413967.1 218706448 7155257 complement(3409748..3411739) 1 NC_011751.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 3411739 tktA 7155257 tktA Escherichia coli UMN026 transketolase YP_002413967.1 3409748 R 585056 CDS YP_002413968.1 218706449 7158074 3412017..3412775 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : putative enzyme; putative peptidase 3412775 yggG 7158074 yggG Escherichia coli UMN026 putative peptidase YP_002413968.1 3412017 D 585056 CDS YP_002413969.1 218706450 7159055 complement(3412861..3414423) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3414423 7159055 ECUMN_3287 Escherichia coli UMN026 hypothetical protein YP_002413969.1 3412861 R 585056 CDS YP_002413970.1 218706451 7155258 complement(3414573..3415493) 1 NC_011751.1 catalyzes the formation of putrescine from agmatine; agmatinase 3415493 speB 7155258 speB Escherichia coli UMN026 agmatinase YP_002413970.1 3414573 R 585056 CDS YP_002413971.1 218706452 7157958 complement(3415629..3416360) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3416360 7157958 ECUMN_3289 Escherichia coli UMN026 hypothetical protein YP_002413971.1 3415629 R 585056 CDS YP_002413972.1 218706453 7155259 complement(3416506..3418482) 1 NC_011751.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 3418482 speA 7155259 speA Escherichia coli UMN026 arginine decarboxylase YP_002413972.1 3416506 R 585056 CDS YP_002413973.1 218706454 7157957 complement(3418491..3418637) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3418637 yqgB 7157957 yqgB Escherichia coli UMN026 hypothetical protein YP_002413973.1 3418491 R 585056 CDS YP_002413974.1 218706455 7159613 3418758..3418973 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3418973 yqgC 7159613 yqgC Escherichia coli UMN026 hypothetical protein YP_002413974.1 3418758 D 585056 CDS YP_002413975.1 218706456 7159614 complement(3418970..3419221) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3419221 yqgD 7159614 yqgD Escherichia coli UMN026 hypothetical protein YP_002413975.1 3418970 R 585056 CDS YP_002413976.1 218706457 7159615 3419277..3420431 1 NC_011751.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3420431 metK 7159615 metK Escherichia coli UMN026 S-adenosylmethionine synthetase YP_002413976.1 3419277 D 585056 CDS YP_002413977.1 218706458 7157109 3420868..3422262 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter; D-galactose transporter 3422262 galP 7157109 galP Escherichia coli UMN026 D-galactose transporter YP_002413977.1 3420868 D 585056 CDS YP_002413978.1 218706459 7156497 3422339..3422836 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204; hypothetical protein 3422836 sprT 7156497 sprT Escherichia coli UMN026 hypothetical protein YP_002413978.1 3422339 D 585056 CDS YP_002413979.1 218706460 7157967 3422931..3423638 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme; DNA-specific endonuclease I 3423638 endA 7157967 endA Escherichia coli UMN026 DNA-specific endonuclease I YP_002413979.1 3422931 D 585056 CDS YP_002413980.1 218706461 7156246 3423718..3424449 1 NC_011751.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3424449 yggJ 7156246 yggJ Escherichia coli UMN026 16S ribosomal RNA methyltransferase RsmE YP_002413980.1 3423718 D 585056 CDS YP_002413981.1 218706462 7159057 3424462..3425412 1 NC_011751.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3425412 gshB 7159057 gshB Escherichia coli UMN026 glutathione synthetase YP_002413981.1 3424462 D 585056 CDS YP_002413982.1 218706463 7156618 3425521..3426084 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3426084 yqgE 7156618 yqgE Escherichia coli UMN026 hypothetical protein YP_002413982.1 3425521 D 585056 CDS YP_002413983.1 218706464 7159616 3426084..3426500 1 NC_011751.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3426500 yqgF 7159616 yqgF Escherichia coli UMN026 Holliday junction resolvase-like protein YP_002413983.1 3426084 D 585056 CDS YP_002413984.1 218706465 7159617 complement(3426615..3427595) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter; transporter 3427595 yggR 7159617 yggR Escherichia coli UMN026 transporter YP_002413984.1 3426615 R 585056 CDS YP_002413985.1 218706466 7159062 3427613..3428317 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3428317 yggS 7159062 yggS Escherichia coli UMN026 hypothetical protein YP_002413985.1 3427613 D 585056 CDS YP_002413986.1 218706467 7159063 3428335..3428901 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3428901 yggT 7159063 yggT Escherichia coli UMN026 hypothetical protein YP_002413986.1 3428335 D 585056 CDS YP_002413987.1 218706468 7159064 3428898..3429188 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589; hypothetical protein 3429188 yggU 7159064 yggU Escherichia coli UMN026 hypothetical protein YP_002413987.1 3428898 D 585056 CDS YP_002413988.1 218706469 7159065 3429196..3429789 1 NC_011751.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 3429789 yggV 7159065 yggV Escherichia coli UMN026 putative deoxyribonucleotide triphosphate pyrophosphatase YP_002413988.1 3429196 D 585056 CDS YP_002413989.1 218706470 7159066 3429782..3430918 1 NC_011751.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3430918 yggW 7159066 yggW Escherichia coli UMN026 coproporphyrinogen III oxidase YP_002413989.1 3429782 D 585056 CDS YP_002413990.1 218706471 7159067 3431231..3432217 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative c4-dicarboxylate transport system binding protein 3432217 7159067 ECUMN_3308 Escherichia coli UMN026 putative c4-dicarboxylate transport system binding protein YP_002413990.1 3431231 D 585056 CDS YP_002413991.1 218706472 7155260 3432253..3432765 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative TRAP-type C4-dicarboxylate transport system, small permease 3432765 7155260 ECUMN_3309 Escherichia coli UMN026 putative TRAP-type C4-dicarboxylate transport system, small permease YP_002413991.1 3432253 D 585056 CDS YP_002413992.1 218706473 7155261 3432765..3434066 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 3434066 ygiK 7155261 ygiK Escherichia coli UMN026 c4-dicarboxylate permease YP_002413992.1 3432765 D 585056 CDS YP_002413993.1 218706474 7159088 complement(3434122..3435129) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3435129 yggM 7159088 yggM Escherichia coli UMN026 hypothetical protein YP_002413993.1 3434122 R 585056 CDS YP_002413994.1 218706475 7159059 complement(3435246..3436292) 1 NC_011751.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 3436292 ansB 7159059 ansB Escherichia coli UMN026 L-asparaginase II YP_002413994.1 3435246 R 585056 CDS YP_002413995.1 218706476 7155746 complement(3436468..3437187) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 3437187 yggN 7155746 yggN Escherichia coli UMN026 hypothetical protein YP_002413995.1 3436468 R 585056 CDS YP_002413996.1 218706477 7159060 complement(3437371..3437697) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3437697 yggL 7159060 yggL Escherichia coli UMN026 hypothetical protein YP_002413996.1 3437371 R 585056 CDS YP_002413997.1 218706478 7159058 complement(3437697..3438416) 1 NC_011751.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3438416 trmB 7159058 trmB Escherichia coli UMN026 tRNA (guanine-N(7)-)-methyltransferase YP_002413997.1 3437697 R 585056 CDS YP_002413998.1 218706479 7159056 3438577..3439629 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme; adenine DNA glycosylase 3439629 mutY 7159056 mutY Escherichia coli UMN026 adenine DNA glycosylase YP_002413998.1 3438577 D 585056 CDS YP_002413999.1 218706480 7157216 3439657..3439932 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor; hypothetical protein 3439932 yggX 7157216 yggX Escherichia coli UMN026 hypothetical protein YP_002413999.1 3439657 D 585056 CDS YP_002414000.1 218706481 7159068 3439997..3441076 1 NC_011751.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3441076 mltC 7159068 mltC Escherichia coli UMN026 murein transglycosylase C YP_002414000.1 3439997 D 585056 CDS YP_002414001.1 218706482 7157141 3441278..3442534 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter; nucleoside transporter 3442534 nupG 7157141 nupG Escherichia coli UMN026 nucleoside transporter YP_002414001.1 3441278 D 585056 CDS YP_002414002.1 218706483 7157337 complement(3442583..3444718) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme; ornithine decarboxylase 3444718 speC 7157337 speC Escherichia coli UMN026 ornithine decarboxylase YP_002414002.1 3442583 R 585056 CDS YP_002414003.1 218706484 7157959 3445111..3445818 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3445818 yqgA 7157959 yqgA Escherichia coli UMN026 hypothetical protein YP_002414003.1 3445111 D 585056 CDS YP_002414004.1 218706485 7155588 3446197..3447462 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase 3447462 7155588 ECUMN_3322 Escherichia coli UMN026 integrase YP_002414004.1 3446197 D 585056 CDS YP_002414005.1 218706486 7155262 3447688..3448761 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pe : putative enzyme; SHI-2 pathogenicity island protein 3448761 7155262 ECUMN_3323 Escherichia coli UMN026 SHI-2 pathogenicity island protein YP_002414005.1 3447688 D 585056 CDS YP_002414006.1 218706487 7155265 3450184..3450588 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 3450588 7155265 ECUMN_3326 Escherichia coli UMN026 putative transposase YP_002414006.1 3450184 D 585056 CDS YP_002414007.1 218706488 7155266 3450585..3450932 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 3450932 7155266 ECUMN_3327 Escherichia coli UMN026 putative transposase ORF2, IS66 family YP_002414007.1 3450585 D 585056 CDS YP_002414008.1 218706489 7155269 complement(3452869..3453420) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative HTH-type transcriptional regulator 3453420 7155269 ECUMN_3330 Escherichia coli UMN026 putative HTH-type transcriptional regulator YP_002414008.1 3452869 R 585056 CDS YP_002414009.1 218706490 7155270 complement(3453683..3454693) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 2895103, 11440716; Product type s : structure; Fimbrial PapG protein 3454693 papG 7155270 papG Escherichia coli UMN026 Fimbrial PapG protein YP_002414009.1 3453683 R 585056 CDS YP_002414010.1 218706491 7157387 complement(3454737..3455267) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2869489, 2895103, 1357526, 8096174, 10049807; Product type s : structure; Fimbrial adapter PapF 3455267 papF 7157387 papF Escherichia coli UMN026 Fimbrial adapter PapF YP_002414010.1 3454737 R 585056 CDS YP_002414011.1 218706492 7157386 complement(3455312..3455857) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; Fimbrial protein 3455857 prsE 7157386 prsE Escherichia coli UMN026 Fimbrial protein YP_002414011.1 3455312 R 585056 CDS YP_002414012.1 218706493 7157547 complement(3455866..3456405) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 8096174, 10049807, 10446050; Product type s : structure; Fimbrial adapter PapK 3456405 papK 7157547 papK Escherichia coli UMN026 Fimbrial adapter PapK YP_002414012.1 3455866 R 585056 CDS YP_002414013.1 218706494 7157391 complement(3456412..3456993) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1975085, 1357526; Product type f : factor; protein PapJ , P pilus assembly 3456993 papJ 7157391 papJ Escherichia coli UMN026 protein PapJ , P pilus assembly YP_002414013.1 3456412 R 585056 CDS YP_002414014.1 218706495 7157390 complement(3457030..3457764) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1357526, 10049807, 2478891, 10446050; Product type f : factor; Chaperone protein PapD 3457764 papD 7157390 papD Escherichia coli UMN026 Chaperone protein PapD YP_002414014.1 3457030 R 585056 CDS YP_002414015.1 218706496 7157385 complement(3457835..3460366) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2897064, 1357526, 12399496, 2572580, 7909802, 9501230; Product type f : factor; Outer membrane usher protein PapC 3460366 papC 7157385 papC Escherichia coli UMN026 Outer membrane usher protein PapC YP_002414015.1 3457835 R 585056 CDS YP_002414016.1 218706497 7157384 complement(3460404..3460991) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2882856, 1357526, 2897064; Product type s : structure; minor pilin protein PapH 3460991 papH 7157384 papH Escherichia coli UMN026 minor pilin protein PapH YP_002414016.1 3460404 R 585056 CDS YP_002414017.1 218706498 7157388 complement(3461061..3461597) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10678978; Product type s : structure; P-fimbriae major subunit 3461597 papA 7157388 papA Escherichia coli UMN026 P-fimbriae major subunit YP_002414017.1 3461061 R 585056 CDS YP_002414018.1 218706499 7157382 complement(3461804..3462118) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2656260, 2868893; Product type r : regulator; pap operon regulatory protein PapB 3462118 papB 7157382 papB Escherichia coli UMN026 pap operon regulatory protein PapB YP_002414018.1 3461804 R 585056 CDS YP_002414019.1 218706500 7157383 3462523..3462756 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2868893, 1357526; Product type r : regulator; pap operon regulatory protein PapI 3462756 papI 7157383 papI Escherichia coli UMN026 pap operon regulatory protein PapI YP_002414019.1 3462523 D 585056 CDS YP_002414020.1 218706501 7155272 complement(3464206..3464532) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS629 3464532 7155272 ECUMN_3344 Escherichia coli UMN026 transposase ORF A, IS629 YP_002414020.1 3464206 R 585056 CDS YP_002414021.1 218706502 7155273 complement(3464805..3464981) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3464981 7155273 ECUMN_3345 Escherichia coli UMN026 hypothetical protein YP_002414021.1 3464805 R 585056 CDS YP_002414022.1 218706503 7155274 complement(3465378..3466010) 1 NC_011751.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; putative transposase (fragment) 3466010 7155274 ECUMN_3346 Escherichia coli UMN026 putative transposase (fragment) YP_002414022.1 3465378 R 585056 CDS YP_002414023.1 218706504 7155275 3466562..3466822 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3466822 7155275 ECUMN_3347 Escherichia coli UMN026 hypothetical protein YP_002414023.1 3466562 D 585056 CDS YP_002414024.1 218706505 7155276 3466864..3467424 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 3467424 7155276 ECUMN_3348 Escherichia coli UMN026 putative transcriptional regulator YP_002414024.1 3466864 D 585056 CDS YP_002414025.1 218706506 7155277 3467434..3467892 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3467892 7155277 ECUMN_3349 Escherichia coli UMN026 hypothetical protein YP_002414025.1 3467434 D 585056 CDS YP_002414026.1 218706507 7155278 complement(3468176..3468448) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type rc : receptor; Neurotensin receptor R8 3468448 7155278 ECUMN_3350 Escherichia coli UMN026 Neurotensin receptor R8 YP_002414026.1 3468176 R 585056 CDS YP_002414027.1 218706508 7155279 complement(3468445..3468660) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3468660 7155279 ECUMN_3351 Escherichia coli UMN026 hypothetical protein YP_002414027.1 3468445 R 585056 CDS YP_002414028.1 218706509 7155280 complement(3468664..3469047) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3469047 7155280 ECUMN_3352 Escherichia coli UMN026 hypothetical protein YP_002414028.1 3468664 R 585056 CDS YP_002414029.1 218706510 7155281 complement(3469044..3469235) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3469235 7155281 ECUMN_3353 Escherichia coli UMN026 hypothetical protein YP_002414029.1 3469044 R 585056 CDS YP_002414030.1 218706511 7155282 complement(3469323..3469643) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3469643 7155282 ECUMN_3354 Escherichia coli UMN026 hypothetical protein YP_002414030.1 3469323 R 585056 CDS YP_002414031.1 218706512 7155283 complement(3469969..3470193) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3470193 7155283 ECUMN_3355 Escherichia coli UMN026 hypothetical protein YP_002414031.1 3469969 R 585056 CDS YP_002414032.1 218706513 7155284 complement(3470427..3472517) 1 NC_011751.1 IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein 3472517 7155284 ECUMN_3356 Escherichia coli UMN026 bifunctional enterobactin receptor/adhesin protein YP_002414032.1 3470427 R 585056 CDS YP_002414033.1 218706514 7155285 complement(3473017..3473922) 1 NC_011751.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3473922 insD 7155285 insD Escherichia coli UMN026 insertion element IS2 transposase InsD YP_002414033.1 3473017 R 585056 CDS YP_002414034.1 218706515 7156826 complement(3473915..3474289) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type r : regulator; IS2 insertion element repressor InsA; KpLE2 phage-like element 3474289 insC 7156826 insC Escherichia coli UMN026 IS2 insertion element repressor InsA; KpLE2 phage-like element YP_002414034.1 3473915 R 585056 CDS YP_002414035.1 218706516 7156825 3474461..3474619 1 NC_011751.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; transposase ORF A (fragment), IS3 family 3474619 7156825 ECUMN_3360 Escherichia coli UMN026 transposase ORF A (fragment), IS3 family YP_002414035.1 3474461 D 585056 CDS YP_002414036.1 218706517 7155287 3474872..3476005 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS110 family 3476005 7155287 ECUMN_3362 Escherichia coli UMN026 transposase, IS110 family YP_002414036.1 3474872 D 585056 CDS YP_002414037.1 218706518 7155289 complement(3477714..3478064) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 3478064 7155289 ECUMN_3364 Escherichia coli UMN026 putative transposase ORF2, IS66 family YP_002414037.1 3477714 R 585056 CDS YP_002414038.1 218706519 7155290 complement(3478061..3478498) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 3478498 7155290 ECUMN_3365 Escherichia coli UMN026 putative transposase YP_002414038.1 3478061 R 585056 CDS YP_002414039.1 218706520 7155291 complement(3478833..3479582) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3479582 7155291 ECUMN_3366 Escherichia coli UMN026 hypothetical protein YP_002414039.1 3478833 R 585056 CDS YP_002414040.1 218706521 7155292 complement(3479461..3483360) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Serine protease 3483360 sat 7155292 sat Escherichia coli UMN026 Serine protease YP_002414040.1 3479461 R 585056 CDS YP_002414041.1 218706522 7157870 3484109..3484306 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3484306 7157870 ECUMN_3369 Escherichia coli UMN026 hypothetical protein YP_002414041.1 3484109 D 585056 CDS YP_002414042.1 218706523 7155293 complement(3484292..3486571) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4313071, 6456229, 7044820, 7042696, 6749806; Product type rc : receptor; Ferric aerobactin receptor 3486571 iutA 7155293 iutA Escherichia coli UMN026 Ferric aerobactin receptor YP_002414042.1 3484292 R 585056 CDS YP_002414043.1 218706524 7156878 complement(3486493..3487830) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme; L-lysine 6-monooxygenase 3487830 iucD 7156878 iucD Escherichia coli UMN026 L-lysine 6-monooxygenase YP_002414043.1 3486493 R 585056 CDS YP_002414044.1 218706525 7156877 complement(3487827..3489569) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; Aerobactin siderophore biosynthesis protein 3489569 iucC 7156877 iucC Escherichia coli UMN026 Aerobactin siderophore biosynthesis protein YP_002414044.1 3487827 R 585056 CDS YP_002414045.1 218706526 7156876 complement(3489569..3490516) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase 3490516 iucB 7156876 iucB Escherichia coli UMN026 aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase YP_002414045.1 3489569 R 585056 CDS YP_002414046.1 218706527 7156875 complement(3490517..3492304) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme; aerobactin siderophore biosynthesis protein 3492304 iucA 7156875 iucA Escherichia coli UMN026 aerobactin siderophore biosynthesis protein YP_002414046.1 3490517 R 585056 CDS YP_002414047.1 218706528 7156874 3492377..3493570 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pt : putative transporter; putative membrane transport protein, major facilitator superfamily 3493570 shiF 7156874 shiF Escherichia coli UMN026 putative membrane transport protein, major facilitator superfamily YP_002414047.1 3492377 D 585056 CDS YP_002414048.1 218706529 7157924 complement(3493729..3494718) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3494718 7157924 ECUMN_3377 Escherichia coli UMN026 hypothetical protein YP_002414048.1 3493729 R 585056 CDS YP_002414049.1 218706530 7155294 3494815..3495549 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; transcriptional regulator 3495549 nanR 7155294 nanR Escherichia coli UMN026 transcriptional regulator YP_002414049.1 3494815 D 585056 CDS YP_002414050.1 218706531 7157237 complement(3495585..3496520) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 3496520 7157237 ECUMN_3379 Escherichia coli UMN026 putative hydrolase YP_002414050.1 3495585 R 585056 CDS YP_002414051.1 218706532 7155295 complement(3496570..3497688) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; N-acetylneuraminic acid mutarotase 3497688 7155295 ECUMN_3380 Escherichia coli UMN026 N-acetylneuraminic acid mutarotase YP_002414051.1 3496570 R 585056 CDS YP_002414052.1 218706533 7155296 complement(3497692..3498432) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15743943; Product type pm : putative membrane component; putative N-acetylneuraminic acid outer membrane channel protein nanC 3498432 7155296 ECUMN_3381 Escherichia coli UMN026 putative N-acetylneuraminic acid outer membrane channel protein nanC YP_002414052.1 3497692 R 585056 CDS YP_002414053.1 218706534 7155297 complement(3498448..3499278) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3499278 7155297 ECUMN_3382 Escherichia coli UMN026 hypothetical protein YP_002414053.1 3498448 R 585056 CDS YP_002414054.1 218706535 7155298 complement(3499282..3500790) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; putative sialic acid transporter 3500790 7155298 ECUMN_3383 Escherichia coli UMN026 putative sialic acid transporter YP_002414054.1 3499282 R 585056 CDS YP_002414055.1 218706536 7155299 complement(3500803..3501678) 1 NC_011751.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3501678 nanK 7155299 nanK Escherichia coli UMN026 N-acetylmannosamine kinase YP_002414055.1 3500803 R 585056 CDS YP_002414056.1 218706537 7157235 complement(3501712..3502629) 1 NC_011751.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3502629 7157235 ECUMN_3385 Escherichia coli UMN026 N-acetylneuraminate lyase YP_002414056.1 3501712 R 585056 CDS YP_002414057.1 218706538 7155300 complement(3502822..3503085) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3503085 7155300 ECUMN_3386 Escherichia coli UMN026 hypothetical protein YP_002414057.1 3502822 R 585056 CDS YP_002414058.1 218706539 7155301 complement(3503060..3503263) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3503263 7155301 ECUMN_3387 Escherichia coli UMN026 hypothetical protein YP_002414058.1 3503060 R 585056 CDS YP_002414059.1 218706540 7155302 3503291..3503716 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 3503716 7155302 ECUMN_3388 Escherichia coli UMN026 putative transposase YP_002414059.1 3503291 D 585056 CDS YP_002414060.1 218706541 7155303 3503713..3504063 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 3504063 7155303 ECUMN_3389 Escherichia coli UMN026 putative transposase ORF2, IS66 family YP_002414060.1 3503713 D 585056 CDS YP_002414061.1 218706542 7155305 3505155..3506729 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase ORF 1, IS66 family 3506729 7155305 ECUMN_3391 Escherichia coli UMN026 putative transposase ORF 1, IS66 family YP_002414061.1 3505155 D 585056 CDS YP_002414062.1 218706543 7155306 complement(3506950..3507333) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3507333 7155306 ECUMN_3392 Escherichia coli UMN026 hypothetical protein YP_002414062.1 3506950 R 585056 CDS YP_002414063.1 218706544 7155307 complement(3507500..3508105) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3508105 7155307 ECUMN_3393 Escherichia coli UMN026 hypothetical protein YP_002414063.1 3507500 R 585056 CDS YP_002414064.1 218706545 7155310 3510155..3510754 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3510754 7155310 ECUMN_3396 Escherichia coli UMN026 hypothetical protein YP_002414064.1 3510155 D 585056 CDS YP_002414065.1 218706546 7155311 complement(3510875..3512383) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3512383 7155311 ECUMN_3397 Escherichia coli UMN026 hypothetical protein YP_002414065.1 3510875 R 585056 CDS YP_002414066.1 218706547 7155312 3513658..3514569 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3514569 7155312 ECUMN_3399 Escherichia coli UMN026 hypothetical protein YP_002414066.1 3513658 D 585056 CDS YP_002414067.1 218706548 7156872 3514897..3518022 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392470, 97257509, 99212225, 2661530, 9298646; Product type h : extrachromosomal origin; antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage 3518022 flu 7156872 flu Escherichia coli UMN026 antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage YP_002414067.1 3514897 D 585056 CDS YP_002414068.1 218706549 7156417 3518137..3520659 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3520659 7156417 ECUMN_3401 Escherichia coli UMN026 hypothetical protein YP_002414068.1 3518137 D 585056 CDS YP_002414069.1 218706550 7155314 3520735..3521190 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3521190 7155314 ECUMN_3402 Escherichia coli UMN026 hypothetical protein YP_002414069.1 3520735 D 585056 CDS YP_002414070.1 218706551 7155315 complement(3521309..3521497) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3521497 7155315 ECUMN_3403 Escherichia coli UMN026 hypothetical protein YP_002414070.1 3521309 R 585056 CDS YP_002414071.1 218706552 7155316 3521601..3522422 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3522422 7155316 ECUMN_3404 Escherichia coli UMN026 hypothetical protein YP_002414071.1 3521601 D 585056 CDS YP_002414072.1 218706553 7155318 3523205..3523651 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor; putative DNA repair protein; CP4-44 prophage 3523651 yeeS 7155318 yeeS Escherichia coli UMN026 putative DNA repair protein; CP4-44 prophage YP_002414072.1 3523205 D 585056 CDS YP_002414073.1 218706554 7158808 3523714..3523935 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 3523935 yeeT 7158808 yeeT Escherichia coli UMN026 hypothetical protein YP_002414073.1 3523714 D 585056 CDS YP_002414074.1 218706555 7158810 3523954..3524598 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3524598 7158810 ECUMN_3409 Escherichia coli UMN026 hypothetical protein YP_002414074.1 3523954 D 585056 CDS YP_002414075.1 218706556 7155319 3524540..3525028 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3525028 7155319 ECUMN_3410 Escherichia coli UMN026 hypothetical protein YP_002414075.1 3524540 D 585056 CDS YP_002414076.1 218706557 7155320 3524946..3525482 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3525482 7155320 ECUMN_3411 Escherichia coli UMN026 hypothetical protein YP_002414076.1 3524946 D 585056 CDS YP_002414077.1 218706558 7155321 3525479..3525967 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3525967 yeeW 7155321 yeeW Escherichia coli UMN026 hypothetical protein YP_002414077.1 3525479 D 585056 CDS YP_002414078.1 218706559 7158812 3525750..3526181 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3526181 7158812 ECUMN_3413 Escherichia coli UMN026 hypothetical protein YP_002414078.1 3525750 D 585056 CDS YP_002414079.1 218706560 7155322 3526263..3527111 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9987116; hypothetical protein 3527111 7155322 ECUMN_3414 Escherichia coli UMN026 hypothetical protein YP_002414079.1 3526263 D 585056 CDS YP_002414080.1 218706561 7155323 3527180..3527575 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3527575 7155323 ECUMN_3415 Escherichia coli UMN026 hypothetical protein YP_002414080.1 3527180 D 585056 CDS YP_002414081.1 218706562 7155324 3527568..3528308 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3528308 7155324 ECUMN_3416 Escherichia coli UMN026 hypothetical protein YP_002414081.1 3527568 D 585056 CDS YP_002414082.1 218706563 7155325 3528280..3528501 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3528501 7155325 ECUMN_3417 Escherichia coli UMN026 hypothetical protein YP_002414082.1 3528280 D 585056 CDS YP_002414083.1 218706564 7155326 3528933..3529088 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3529088 7155326 ECUMN_3418 Escherichia coli UMN026 hypothetical protein YP_002414083.1 3528933 D 585056 CDS YP_002414084.1 218706565 7155327 3529863..3530882 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8253690; Product type e : enzyme; polysialic acid capsule expression protein 3530882 kpsF 7155327 kpsF Escherichia coli UMN026 polysialic acid capsule expression protein YP_002414084.1 3529863 D 585056 CDS YP_002414085.1 218706566 7156912 3530954..3532102 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8253690; Product type t : transporter; Capsule polysaccharide export inner-membrane protein 3532102 kpsE 7156912 kpsE Escherichia coli UMN026 Capsule polysaccharide export inner-membrane protein YP_002414085.1 3530954 D 585056 CDS YP_002414086.1 218706567 7156911 3532123..3533802 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021185; Product type t : transporter; polysialic acid transport protein 3533802 kpsD 7156911 kpsD Escherichia coli UMN026 polysialic acid transport protein YP_002414086.1 3532123 D 585056 CDS YP_002414087.1 218706568 7156910 3533812..3534552 1 NC_011751.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3534552 kpsU 7156910 kpsU Escherichia coli UMN026 3-deoxy-manno-octulosonate cytidylyltransferase YP_002414087.1 3533812 D 585056 CDS YP_002414088.1 218706569 7156916 3534549..3536576 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter; Capsule polysaccharide export protein 3536576 kpsC 7156916 kpsC Escherichia coli UMN026 Capsule polysaccharide export protein YP_002414088.1 3534549 D 585056 CDS YP_002414089.1 218706570 7156909 3536611..3537843 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter; Capsule polysaccharide export protein 3537843 kpsS 7156909 kpsS Escherichia coli UMN026 Capsule polysaccharide export protein YP_002414089.1 3536611 D 585056 CDS YP_002414090.1 218706571 7156914 complement(3538491..3538763) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3538763 7156914 ECUMN_3425 Escherichia coli UMN026 hypothetical protein YP_002414090.1 3538491 R 585056 CDS YP_002414091.1 218706572 7155328 3538833..3538934 1 NC_011751.1 putative integrase core domain protein (fragment) 3538934 7155328 ECUMN_3426 Escherichia coli UMN026 putative integrase core domain protein (fragment) YP_002414091.1 3538833 D 585056 CDS YP_002414092.1 218706573 7155329 complement(3539416..3540993) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein 3540993 7155329 ECUMN_3427 Escherichia coli UMN026 hypothetical protein YP_002414092.1 3539416 R 585056 CDS YP_002414093.1 218706574 7155330 complement(3540990..3541430) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein 3541430 7155330 ECUMN_3428 Escherichia coli UMN026 hypothetical protein YP_002414093.1 3540990 R 585056 CDS YP_002414094.1 218706575 7155331 complement(3541342..3542088) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10699509, 11230405; hypothetical protein 3542088 7155331 ECUMN_3429 Escherichia coli UMN026 hypothetical protein YP_002414094.1 3541342 R 585056 CDS YP_002414095.1 218706576 7155332 complement(3542126..3544627) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3544627 7155332 ECUMN_3430 Escherichia coli UMN026 hypothetical protein YP_002414095.1 3542126 R 585056 CDS YP_002414096.1 218706577 7155333 complement(3544835..3545521) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 8051103, 2082146; Product type e : enzyme; polysialic acid transport ATP-binding protein 3545521 kpsT 7155333 kpsT Escherichia coli UMN026 polysialic acid transport ATP-binding protein YP_002414096.1 3544835 R 585056 CDS YP_002414097.1 218706578 7156915 complement(3545687..3549433) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3549433 7156915 ECUMN_3432 Escherichia coli UMN026 hypothetical protein YP_002414097.1 3545687 R 585056 CDS YP_002414098.1 218706579 7155334 complement(3549453..3550445) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative Capsule biosynthesis protein 3550445 7155334 ECUMN_3433 Escherichia coli UMN026 putative Capsule biosynthesis protein YP_002414098.1 3549453 R 585056 CDS YP_002414099.1 218706580 7155335 complement(3550545..3551381) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 7715449; Product type t : transporter; polysialic acid transport protein 3551381 kpsM 7155335 kpsM Escherichia coli UMN026 polysialic acid transport protein YP_002414099.1 3550545 R 585056 CDS YP_002414100.1 218706581 7156913 complement(3552378..3552914) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein YghD 3552914 yghD 7156913 yghD Escherichia coli UMN026 putative general secretion pathway protein YghD YP_002414100.1 3552378 R 585056 CDS YP_002414101.1 218706582 7159071 complement(3552916..3554094) 1 NC_011751.1 similar to general secretory pathway protein L; GspL-like protein 3554094 yghE 7159071 yghE Escherichia coli UMN026 GspL-like protein YP_002414101.1 3552916 R 585056 CDS YP_002414102.1 218706583 7159072 complement(3554091..3555068) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type II secretion protein 3555068 7159072 ECUMN_3437 Escherichia coli UMN026 putative type II secretion protein YP_002414102.1 3554091 R 585056 CDS YP_002414103.1 218706584 7155336 complement(3555065..3555670) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3555670 7155336 ECUMN_3438 Escherichia coli UMN026 hypothetical protein YP_002414103.1 3555065 R 585056 CDS YP_002414104.1 218706585 7155337 complement(3555667..3556038) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative type II secretion protein 3556038 7155337 ECUMN_3439 Escherichia coli UMN026 putative type II secretion protein YP_002414104.1 3555667 R 585056 CDS YP_002414105.1 218706586 7155338 complement(3556035..3556598) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3556598 7155338 ECUMN_3440 Escherichia coli UMN026 hypothetical protein YP_002414105.1 3556035 R 585056 CDS YP_002414106.1 218706587 7155339 complement(3556602..3557084) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative general secretion pathway protein G (epsG-like) 3557084 7155339 ECUMN_3441 Escherichia coli UMN026 putative general secretion pathway protein G (epsG-like) YP_002414106.1 3556602 R 585056 CDS YP_002414107.1 218706588 7155340 complement(3557074..3558297) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General secretion pathway protein F 3558297 epsF 7155340 epsF Escherichia coli UMN026 General secretion pathway protein F YP_002414107.1 3557074 R 585056 CDS YP_002414108.1 218706589 7156264 complement(3558297..3559790) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein E 3559790 epsE 7156264 epsE Escherichia coli UMN026 general secretion pathway protein E YP_002414108.1 3558297 R 585056 CDS YP_002414109.1 218706590 7156263 complement(3559790..3561850) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein D 3561850 epsD 7156263 epsD Escherichia coli UMN026 general secretion pathway protein D YP_002414109.1 3559790 R 585056 CDS YP_002414110.1 218706591 7156262 complement(3561880..3562839) 1 NC_011751.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; putative type II secretion protein GspC 3562839 yghF 7156262 yghF Escherichia coli UMN026 putative type II secretion protein GspC YP_002414110.1 3561880 R 585056 CDS YP_002414111.1 218706592 7159073 complement(3562857..3563267) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3563267 yghG 7159073 yghG Escherichia coli UMN026 hypothetical protein YP_002414111.1 3562857 R 585056 CDS YP_002414112.1 218706593 7159074 complement(3563333..3564142) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme; bifunctional prepilin leader peptidase and methylase 3564142 pppA 7159074 pppA Escherichia coli UMN026 bifunctional prepilin leader peptidase and methylase YP_002414112.1 3563333 R 585056 CDS YP_002414113.1 218706594 7157510 complement(3564272..3568834) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein; inner membrane lipoprotein 3568834 yghJ 7157510 yghJ Escherichia coli UMN026 inner membrane lipoprotein YP_002414113.1 3564272 R 585056 CDS YP_002414114.1 218706595 7159075 3568985..3569194 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3569194 7159075 ECUMN_3449 Escherichia coli UMN026 hypothetical protein YP_002414114.1 3568985 D 585056 CDS YP_002414115.1 218706596 7155341 complement(3569320..3571002) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11785976, 21178909, 11283302; Product type t : transporter; glycolate transporter 3571002 yghK 7155341 yghK Escherichia coli UMN026 glycolate transporter YP_002414115.1 3569320 R 585056 CDS YP_002414116.1 218706597 7155902 complement(3571357..3573528) 1 NC_011751.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 3573528 glcB 7155902 glcB Escherichia coli UMN026 malate synthase G YP_002414116.1 3571357 R 585056 CDS YP_002414117.1 218706598 7156530 complement(3573550..3573954) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3573954 glcG 7156530 glcG Escherichia coli UMN026 hypothetical protein YP_002414117.1 3573550 R 585056 CDS YP_002414118.1 218706599 7156535 complement(3573959..3575182) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type c : carrier; glycolate oxidase iron-sulfur subunit 3575182 glcF 7156535 glcF Escherichia coli UMN026 glycolate oxidase iron-sulfur subunit YP_002414118.1 3573959 R 585056 CDS YP_002414119.1 218706600 7156534 complement(3575193..3576245) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme; glycolate oxidase FAD binding subunit 3576245 glcE 7156534 glcE Escherichia coli UMN026 glycolate oxidase FAD binding subunit YP_002414119.1 3575193 R 585056 CDS YP_002414120.1 218706601 7156533 complement(3576245..3577744) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme; glycolate oxidase subunit GlcD 3577744 glcD 7156533 glcD Escherichia coli UMN026 glycolate oxidase subunit GlcD YP_002414120.1 3576245 R 585056 CDS YP_002414121.1 218706602 7156532 3577995..3578759 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 9880556, 8606183; Product type r : regulator; DNA-binding transcriptional regulator GlcC 3578759 glcC 7156532 glcC Escherichia coli UMN026 DNA-binding transcriptional regulator GlcC YP_002414121.1 3577995 D 585056 CDS YP_002414122.1 218706603 7156531 complement(3578766..3579908) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3579908 yghO 7156531 yghO Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414122.1 3578766 R 585056 CDS YP_002414123.1 218706604 7159077 3580253..3582934 1 NC_011751.1 activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3582934 7159077 ECUMN_3458 Escherichia coli UMN026 acyl-CoA synthetase YP_002414123.1 3580253 D 585056 CDS YP_002414124.1 218706605 7155342 3582966..3583214 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3583214 7155342 ECUMN_3460 Escherichia coli UMN026 hypothetical protein YP_002414124.1 3582966 D 585056 CDS YP_002414125.1 218706606 7155343 3583214..3584386 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 8-amino-7-oxononanoate synthase 3584386 7155343 ECUMN_3461 Escherichia coli UMN026 putative 8-amino-7-oxononanoate synthase YP_002414125.1 3583214 D 585056 CDS YP_002414126.1 218706607 7155346 complement(3585497..3586567) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3586567 7155346 ECUMN_3464 Escherichia coli UMN026 hypothetical protein YP_002414126.1 3585497 R 585056 CDS YP_002414127.1 218706608 7155347 complement(3586598..3587161) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3587161 7155347 ECUMN_3465 Escherichia coli UMN026 putative transcriptional regulator YP_002414127.1 3586598 R 585056 CDS YP_002414128.1 218706609 7155348 complement(3587170..3587994) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3587994 7155348 ECUMN_3466 Escherichia coli UMN026 hypothetical protein YP_002414128.1 3587170 R 585056 CDS YP_002414129.1 218706610 7155349 complement(3587994..3589343) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 3589343 7155349 ECUMN_3467 Escherichia coli UMN026 hypothetical protein YP_002414129.1 3587994 R 585056 CDS YP_002414130.1 218706611 7155350 complement(3589389..3590147) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3590147 yghR 7155350 yghR Escherichia coli UMN026 hypothetical protein YP_002414130.1 3589389 R 585056 CDS YP_002414131.1 218706612 7159078 complement(3590179..3590892) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3590892 yghS 7159078 yghS Escherichia coli UMN026 hypothetical protein YP_002414131.1 3590179 R 585056 CDS YP_002414132.1 218706613 7159079 3591066..3591758 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3591758 yghT 7159079 yghT Escherichia coli UMN026 hypothetical protein YP_002414132.1 3591066 D 585056 CDS YP_002414133.1 218706614 7159080 complement(3591807..3593306) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21336523, 21382172, 7775463; Product type t : transporter; phosphate transporter 3593306 pitB 7159080 pitB Escherichia coli UMN026 phosphate transporter YP_002414133.1 3591807 R 585056 CDS YP_002414134.1 218706615 7157469 complement(3593598..3595457) 1 NC_011751.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 3595457 gss 7157469 gss Escherichia coli UMN026 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_002414134.1 3593598 R 585056 CDS YP_002414135.1 218706616 7156620 3595662..3596528 1 NC_011751.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3596528 yghU 7156620 yghU Escherichia coli UMN026 putative glutathione S-transferase YghU YP_002414135.1 3595662 D 585056 CDS YP_002414136.1 218706617 7159081 complement(3596760..3597008) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : putative factor; hydrogenase 2 accessory protein HypG 3597008 hybG 7159081 hybG Escherichia coli UMN026 hydrogenase 2 accessory protein HypG YP_002414136.1 3596760 R 585056 CDS YP_002414137.1 218706618 7156746 complement(3597021..3597362) 1 NC_011751.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3597362 hybF 7156746 hybF Escherichia coli UMN026 hydrogenase nickel incorporation protein HybF YP_002414137.1 3597021 R 585056 CDS YP_002414138.1 218706619 7156745 complement(3597355..3597843) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor; hydrogenase 2-specific chaperone 3597843 hybE 7156745 hybE Escherichia coli UMN026 hydrogenase 2-specific chaperone YP_002414138.1 3597355 R 585056 CDS YP_002414139.1 218706620 7156744 complement(3597836..3598330) 1 NC_011751.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3598330 hybD 7156744 hybD Escherichia coli UMN026 hydrogenase 2 maturation endopeptidase YP_002414139.1 3597836 R 585056 CDS YP_002414140.1 218706621 7156743 complement(3598330..3600033) 1 NC_011751.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3600033 hybC 7156743 hybC Escherichia coli UMN026 hydrogenase 2 large subunit YP_002414140.1 3598330 R 585056 CDS YP_002414141.1 218706622 7156742 complement(3600030..3601208) 1 NC_011751.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit 3601208 hybB 7156742 hybB Escherichia coli UMN026 putative hydrogenase 2 b cytochrome subunit YP_002414141.1 3600030 R 585056 CDS YP_002414142.1 218706623 7156741 complement(3601198..3602184) 1 NC_011751.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3602184 hybA 7156741 hybA Escherichia coli UMN026 hydrogenase 2 protein HybA YP_002414142.1 3601198 R 585056 CDS YP_002414143.1 218706624 7156740 complement(3602187..3603305) 1 NC_011751.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3603305 hybO 7156740 hybO Escherichia coli UMN026 hydrogenase 2 small subunit YP_002414143.1 3602187 R 585056 CDS YP_002414144.1 218706625 7156747 complement(3603312..3603497) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3603497 7156747 ECUMN_3482 Escherichia coli UMN026 hypothetical protein YP_002414144.1 3603312 R 585056 CDS YP_002414145.1 218706626 7155351 complement(3603494..3603781) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3603781 yghW 7155351 yghW Escherichia coli UMN026 hypothetical protein YP_002414145.1 3603494 R 585056 CDS YP_002414146.1 218706627 7159082 complement(3603900..3604826) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3604826 7159082 ECUMN_3484 Escherichia coli UMN026 hypothetical protein YP_002414146.1 3603900 R 585056 CDS YP_002414147.1 218706628 7155352 3604944..3605984 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme; aldo-keto reductase 3605984 yghZ 7155352 yghZ Escherichia coli UMN026 aldo-keto reductase YP_002414147.1 3604944 D 585056 CDS YP_002414148.1 218706629 7159083 complement(3606024..3606518) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3606518 yqhA 7159083 yqhA Escherichia coli UMN026 hypothetical protein YP_002414148.1 3606024 R 585056 CDS YP_002414149.1 218706630 7159618 3606709..3607593 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; oxidoreductase 3607593 yghA 7159618 yghA Escherichia coli UMN026 oxidoreductase YP_002414149.1 3606709 D 585056 CDS YP_002414150.1 218706631 7159069 complement(3607703..3608212) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 3608212 7159069 ECUMN_3488 Escherichia coli UMN026 transposase IS605 family, IS200 group YP_002414150.1 3607703 R 585056 CDS YP_002414151.1 218706632 7155353 complement(3608118..3608306) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3608306 7155353 ECUMN_3489 Escherichia coli UMN026 hypothetical protein YP_002414151.1 3608118 R 585056 CDS YP_002414152.1 218706633 7155354 complement(3608576..3609001) 1 NC_011751.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3609001 exbD 7155354 exbD Escherichia coli UMN026 biopolymer transport protein ExbD YP_002414152.1 3608576 R 585056 CDS YP_002414153.1 218706634 7156288 complement(3609008..3609742) 1 NC_011751.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3609742 exbB 7156288 exbB Escherichia coli UMN026 biopolymer transport protein ExbB YP_002414153.1 3609008 R 585056 CDS YP_002414154.1 218706635 7156287 3609994..3611181 1 NC_011751.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3611181 metC 7156287 metC Escherichia coli UMN026 cystathionine beta-lyase YP_002414154.1 3609994 D 585056 CDS YP_002414155.1 218706636 7157102 3611321..3611980 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3611980 yghB 7157102 yghB Escherichia coli UMN026 hypothetical protein YP_002414155.1 3611321 D 585056 CDS YP_002414156.1 218706637 7159070 complement(3612020..3612976) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3612976 yqhC 7159070 yqhC Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414156.1 3612020 R 585056 CDS YP_002414157.1 218706638 7159619 3613113..3614276 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme; alcohol dehydrogenase 3614276 yqhD 7159619 yqhD Escherichia coli UMN026 alcohol dehydrogenase YP_002414157.1 3613113 D 585056 CDS YP_002414158.1 218706639 7159620 3614381..3615208 1 NC_011751.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3615208 dkgA 7159620 dkgA Escherichia coli UMN026 2,5-diketo-D-gluconate reductase A YP_002414158.1 3614381 D 585056 CDS YP_002414159.1 218706640 7156175 3615408..3616334 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3616334 yqhG 7156175 yqhG Escherichia coli UMN026 hypothetical protein YP_002414159.1 3615408 D 585056 CDS YP_002414160.1 218706641 7159621 3616385..3616642 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative outer membrane lipoprotein 3616642 yqhH 7159621 yqhH Escherichia coli UMN026 putative outer membrane lipoprotein YP_002414160.1 3616385 D 585056 CDS YP_002414161.1 218706642 7159622 complement(3616685..3618904) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3618904 ygiQ 7159622 ygiQ Escherichia coli UMN026 hypothetical protein YP_002414161.1 3616685 R 585056 CDS YP_002414162.1 218706643 7159091 complement(3619015..3620427) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator; repressor protein for FtsI 3620427 sufI 7159091 sufI Escherichia coli UMN026 repressor protein for FtsI YP_002414162.1 3619015 R 585056 CDS YP_002414163.1 218706644 7158007 complement(3620502..3621239) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3621239 plsC 7158007 plsC Escherichia coli UMN026 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002414163.1 3620502 R 585056 CDS YP_002414164.1 218706645 7157473 complement(3621287..3621442) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3621442 7157473 ECUMN_3502 Escherichia coli UMN026 hypothetical protein YP_002414164.1 3621287 R 585056 CDS YP_002414165.1 218706646 7155355 complement(3621473..3623731) 1 NC_011751.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3623731 parC 7155355 parC Escherichia coli UMN026 DNA topoisomerase IV subunit A YP_002414165.1 3621473 R 585056 CDS YP_002414166.1 218706647 7157392 complement(3623869..3625476) 1 NC_011751.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein 3625476 ygiS 7157392 ygiS Escherichia coli UMN026 putative binding protein YP_002414166.1 3623869 R 585056 CDS YP_002414167.1 218706648 7159092 complement(3625609..3626004) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3626004 ygiT 7159092 ygiT Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414167.1 3625609 R 585056 CDS YP_002414168.1 218706649 7159093 complement(3626006..3626302) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16352847, 12952533, 14727089; Product type r : regulator; motility quorum-sensing regulator 3626302 mqsR 7159093 mqsR Escherichia coli UMN026 motility quorum-sensing regulator YP_002414168.1 3626006 R 585056 CDS YP_002414169.1 218706650 7157171 complement(3626507..3626989) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3626989 ygiV 7157171 ygiV Escherichia coli UMN026 putative transcriptional regulator YP_002414169.1 3626507 R 585056 CDS YP_002414170.1 218706651 7159094 complement(3627042..3627434) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein 3627434 ygiW 7159094 ygiW Escherichia coli UMN026 hypothetical protein YP_002414170.1 3627042 R 585056 CDS YP_002414171.1 218706652 7159095 3627586..3628245 1 NC_011751.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3628245 qseB 7159095 qseB Escherichia coli UMN026 DNA-binding transcriptional regulator QseB YP_002414171.1 3627586 D 585056 CDS YP_002414172.1 218706653 7157610 3628242..3629591 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21927389; Product type r : regulator; sensor protein QseC 3629591 qseC 7157610 qseC Escherichia coli UMN026 sensor protein QseC YP_002414172.1 3628242 D 585056 CDS YP_002414173.1 218706654 7157611 complement(3629637..3629969) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3629969 ygiZ 7157611 ygiZ Escherichia coli UMN026 hypothetical protein YP_002414173.1 3629637 R 585056 CDS YP_002414174.1 218706655 7159096 3630297..3630878 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier; NADPH quinone reductase 3630878 mdaB 7159096 mdaB Escherichia coli UMN026 NADPH quinone reductase YP_002414174.1 3630297 D 585056 CDS YP_002414175.1 218706656 7157068 3630909..3631223 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme; quinol monooxygenase 3631223 ygiN 7157068 ygiN Escherichia coli UMN026 quinol monooxygenase YP_002414175.1 3630909 D 585056 CDS YP_002414176.1 218706657 7159089 complement(3631271..3633163) 1 NC_011751.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3633163 parE 7159089 parE Escherichia coli UMN026 DNA topoisomerase IV subunit B YP_002414176.1 3631271 R 585056 CDS YP_002414177.1 218706658 7157393 complement(3633192..3633773) 1 NC_011751.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3633773 yqiA 7157393 yqiA Escherichia coli UMN026 esterase YqiA YP_002414177.1 3633192 R 585056 CDS YP_002414178.1 218706659 7159623 complement(3633773..3634600) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme; cyclic 3',5'-adenosine monophosphate phosphodiesterase 3634600 cpdA 7159623 cpdA Escherichia coli UMN026 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002414178.1 3633773 R 585056 CDS YP_002414179.1 218706660 7156000 complement(3634625..3635047) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3635047 yqiB 7156000 yqiB Escherichia coli UMN026 hypothetical protein YP_002414179.1 3634625 R 585056 CDS YP_002414180.1 218706661 7159624 complement(3635048..3635677) 1 NC_011751.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 3635677 nudF 7159624 nudF Escherichia coli UMN026 ADP-ribose pyrophosphatase NudF YP_002414180.1 3635048 R 585056 CDS YP_002414181.1 218706662 7157320 3635882..3637363 1 NC_011751.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3637363 tolC 7157320 tolC Escherichia coli UMN026 outer membrane channel protein YP_002414181.1 3635882 D 585056 CDS YP_002414182.1 218706663 7158083 3637607..3638182 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3638182 ygiB 7158083 ygiB Escherichia coli UMN026 hypothetical protein YP_002414182.1 3637607 D 585056 CDS YP_002414183.1 218706664 7159084 3638188..3639348 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3639348 ygiC 7159084 ygiC Escherichia coli UMN026 hypothetical protein YP_002414183.1 3638188 D 585056 CDS YP_002414184.1 218706665 7159085 3639833..3641629 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme; arylsulfate sulfotransferase 3641629 assT 7159085 assT Escherichia coli UMN026 arylsulfate sulfotransferase YP_002414184.1 3639833 D 585056 CDS YP_002414185.1 218706666 7155821 3641647..3642315 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme; Thiol:disulfide interchange protein dsbA 3642315 dsbA 7155821 dsbA Escherichia coli UMN026 Thiol:disulfide interchange protein dsbA YP_002414185.1 3641647 D 585056 CDS YP_002414186.1 218706667 7156201 3642330..3643001 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : putative enzyme; putative disulfide oxidoreductase 3643001 7156201 ECUMN_3525 Escherichia coli UMN026 putative disulfide oxidoreductase YP_002414186.1 3642330 D 585056 CDS YP_002414187.1 218706668 7155356 complement(3643047..3643862) 1 NC_011751.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3643862 zupT 7155356 zupT Escherichia coli UMN026 hypothetical protein YP_002414187.1 3643047 R 585056 CDS YP_002414188.1 218706669 7159695 3643978..3644751 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter; zinc transporter ZupT 3644751 ygiE 7159695 ygiE Escherichia coli UMN026 zinc transporter ZupT YP_002414188.1 3643978 D 585056 CDS YP_002414189.1 218706670 7159086 complement(3644809..3645003) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3645003 7159086 ECUMN_3528 Escherichia coli UMN026 hypothetical protein YP_002414189.1 3644809 R 585056 CDS YP_002414190.1 218706671 7155357 complement(3645241..3645894) 1 NC_011751.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3645894 ribB 7155357 ribB Escherichia coli UMN026 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002414190.1 3645241 R 585056 CDS YP_002414191.1 218706672 7157683 3646208..3646567 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3646567 yqiC 7157683 yqiC Escherichia coli UMN026 hypothetical protein YP_002414191.1 3646208 D 585056 CDS YP_002414192.1 218706673 7159625 complement(3646602..3646802) 1 NC_011751.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3646802 glgS 7159625 glgS Escherichia coli UMN026 glycogen synthesis protein GlgS YP_002414192.1 3646602 R 585056 CDS YP_002414193.1 218706674 7156541 3647071..3647700 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3647700 yqiJ 7156541 yqiJ Escherichia coli UMN026 hypothetical protein YP_002414193.1 3647071 D 585056 CDS YP_002414194.1 218706675 7159626 3647727..3649388 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3649388 yqiK 7159626 yqiK Escherichia coli UMN026 hypothetical protein YP_002414194.1 3647727 D 585056 CDS YP_002414195.1 218706676 7157850 complement(3650184..3651617) 1 NC_011751.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3651617 rfaE 7157850 rfaE Escherichia coli UMN026 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002414195.1 3650184 R 585056 CDS YP_002414196.1 218706677 7157653 complement(3651665..3654505) 1 NC_011751.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3654505 glnE 7157653 glnE Escherichia coli UMN026 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002414196.1 3651665 R 585056 CDS YP_002414197.1 218706678 7156551 complement(3654528..3655829) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : putative enzyme; putative adenylate cyclase 3655829 ygiF 7156551 ygiF Escherichia coli UMN026 putative adenylate cyclase YP_002414197.1 3654528 R 585056 CDS YP_002414198.1 218706679 7159087 complement(3655846..3656052) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3656052 7159087 ECUMN_3537 Escherichia coli UMN026 hypothetical protein YP_002414198.1 3655846 R 585056 CDS YP_002414199.1 218706680 7155358 3656071..3656691 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : putative regulator; putative signal transduction protein 3656691 htrG 7155358 htrG Escherichia coli UMN026 putative signal transduction protein YP_002414199.1 3656071 D 585056 CDS YP_002414200.1 218706681 7156730 3656755..3657993 1 NC_011751.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3657993 cca 7156730 cca Escherichia coli UMN026 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002414200.1 3656755 D 585056 CDS YP_002414201.1 218706682 7155925 complement(3658084..3658905) 1 NC_011751.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3658905 bacA 7155925 bacA Escherichia coli UMN026 undecaprenyl pyrophosphate phosphatase YP_002414201.1 3658084 R 585056 CDS YP_002414202.1 218706683 7155848 complement(3658996..3659364) 1 NC_011751.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3659364 folB 7155848 folB Escherichia coli UMN026 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_002414202.1 3658996 R 585056 CDS YP_002414203.1 218706684 7156424 3659469..3660086 1 NC_011751.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3660086 plsY 7156424 plsY Escherichia coli UMN026 putative glycerol-3-phosphate acyltransferase PlsY YP_002414203.1 3659469 D 585056 CDS YP_002414204.1 218706685 7157475 complement(3660099..3661031) 1 NC_011751.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR 3661031 ygiP 7157475 ygiP Escherichia coli UMN026 transcriptional activator TtdR YP_002414204.1 3660099 R 585056 CDS YP_002414205.1 218706686 7159090 3661238..3662149 1 NC_011751.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3662149 ttdA 7159090 ttdA Escherichia coli UMN026 tartrate dehydratase subunit alpha YP_002414205.1 3661238 D 585056 CDS YP_002414206.1 218706687 7158136 3662146..3662751 1 NC_011751.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3662751 ttdB 7158136 ttdB Escherichia coli UMN026 L(+)-tartrate dehydratase subunit beta YP_002414206.1 3662146 D 585056 CDS YP_002414207.1 218706688 7158137 3662800..3664263 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative tartrate:succinate antiporter 3664263 ygjE 7158137 ygjE Escherichia coli UMN026 putative tartrate:succinate antiporter YP_002414207.1 3662800 D 585056 CDS YP_002414208.1 218706689 7159097 complement(3664306..3665319) 1 NC_011751.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 3665319 gcp 7159097 gcp Escherichia coli UMN026 putative DNA-binding/iron metalloprotein/AP endonuclease YP_002414208.1 3664306 R 585056 CDS YP_002414209.1 218706690 7156519 3665557..3665772 1 NC_011751.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3665772 rpsU 7156519 rpsU Escherichia coli UMN026 30S ribosomal protein S21 YP_002414209.1 3665557 D 585056 CDS YP_002414210.1 218706691 7157787 3665883..3667628 1 NC_011751.1 synthesizes RNA primers at the replication forks; DNA primase 3667628 dnaG 7157787 dnaG Escherichia coli UMN026 DNA primase YP_002414210.1 3665883 D 585056 CDS YP_002414211.1 218706692 7156187 3667823..3669664 1 NC_011751.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3669664 rpoD 7156187 rpoD Escherichia coli UMN026 RNA polymerase sigma factor RpoD YP_002414211.1 3667823 D 585056 CDS YP_002414212.1 218706693 7157760 complement(3669743..3670249) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme; G/U mismatch-specific DNA glycosylase 3670249 ygjF 7157760 ygjF Escherichia coli UMN026 G/U mismatch-specific DNA glycosylase YP_002414212.1 3669743 R 585056 CDS YP_002414213.1 218706694 7155589 complement(3670503..3671267) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative siderophore interacting protein 3671267 yqjH 7155589 yqjH Escherichia coli UMN026 putative siderophore interacting protein YP_002414213.1 3670503 R 585056 CDS YP_002414214.1 218706695 7159635 3671544..3672167 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 3672167 yqjI 7159635 yqjI Escherichia coli UMN026 putative transcriptional regulator YP_002414214.1 3671544 D 585056 CDS YP_002414215.1 218706696 7159636 complement(3672272..3673792) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator; fused signal transducer/methyl accepting chemotaxis protein 3673792 aer 7159636 aer Escherichia coli UMN026 fused signal transducer/methyl accepting chemotaxis protein YP_002414215.1 3672272 R 585056 CDS YP_002414216.1 218706697 7155706 3674183..3675589 1 NC_011751.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3675589 ygjG 7155706 ygjG Escherichia coli UMN026 putrescine--2-oxoglutarate aminotransferase YP_002414216.1 3674183 D 585056 CDS YP_002414217.1 218706698 7159099 complement(3675631..3675963) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 11101501; hypothetical protein 3675963 ygjH 7159099 ygjH Escherichia coli UMN026 hypothetical protein YP_002414217.1 3675631 R 585056 CDS YP_002414218.1 218706699 7159100 3676182..3677165 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89128452, 2515108, 3939708; Product type r : regulator; DNA-binding transcriptional repressor EbgR 3677165 ebgR 7159100 ebgR Escherichia coli UMN026 DNA-binding transcriptional repressor EbgR YP_002414218.1 3676182 D 585056 CDS YP_002414219.1 218706700 7156221 3677349..3680441 1 NC_011751.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3680441 ebgA 7156221 ebgA Escherichia coli UMN026 cryptic beta-D-galactosidase subunit alpha YP_002414219.1 3677349 D 585056 CDS YP_002414220.1 218706701 7156219 3680438..3680887 1 NC_011751.1 in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3680887 ebgC 7156219 ebgC Escherichia coli UMN026 cryptic beta-D-galactosidase subunit beta YP_002414220.1 3680438 D 585056 CDS YP_002414221.1 218706702 7156220 3680950..3682383 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3682383 ygjI 7156220 ygjI Escherichia coli UMN026 putative transporter YP_002414221.1 3680950 D 585056 CDS YP_002414222.1 218706703 7159101 3682517..3683587 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3683587 ygjJ 7159101 ygjJ Escherichia coli UMN026 hypothetical protein YP_002414222.1 3682517 D 585056 CDS YP_002414223.1 218706704 7159102 3683604..3685955 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213393; Product type pe : putative enzyme; putative glycosyl hydrolase 3685955 ygjK 7159102 ygjK Escherichia coli UMN026 putative glycosyl hydrolase YP_002414223.1 3683604 D 585056 CDS YP_002414224.1 218706705 7159103 3686126..3688144 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme; 2,4-dienoyl-CoA reductase, NADH and FMN-linked 3688144 fadH 7159103 fadH Escherichia coli UMN026 2,4-dienoyl-CoA reductase, NADH and FMN-linked YP_002414224.1 3686126 D 585056 CDS YP_002414225.1 218706706 7156306 complement(3688189..3688605) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3688605 ygjM 7156306 ygjM Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414225.1 3688189 R 585056 CDS YP_002414226.1 218706707 7159104 complement(3688602..3688916) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3688916 ygjN 7159104 ygjN Escherichia coli UMN026 hypothetical protein YP_002414226.1 3688602 R 585056 CDS YP_002414227.1 218706708 7159105 complement(3689201..3690337) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase small domain 3690337 ygjO 7159105 ygjO Escherichia coli UMN026 putative methyltransferase small domain YP_002414227.1 3689201 R 585056 CDS YP_002414228.1 218706709 7159106 3690422..3690925 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative metal dependent hydrolase 3690925 ygjP 7159106 ygjP Escherichia coli UMN026 putative metal dependent hydrolase YP_002414228.1 3690422 D 585056 CDS YP_002414229.1 218706710 7159107 3691002..3691685 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative thioredoxin-like 3691685 ygjQ 7159107 ygjQ Escherichia coli UMN026 putative thioredoxin-like YP_002414229.1 3691002 D 585056 CDS YP_002414230.1 218706711 7159108 3691746..3692750 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative NAD(P)-binding dehydrogenase 3692750 ygjR 7159108 ygjR Escherichia coli UMN026 putative NAD(P)-binding dehydrogenase YP_002414230.1 3691746 D 585056 CDS YP_002414231.1 218706712 7157971 3693033..3693998 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : putative membrane component; hypothetical protein 3693998 alx 7157971 alx Escherichia coli UMN026 hypothetical protein YP_002414231.1 3693033 D 585056 CDS YP_002414232.1 218706713 7155732 3694614..3695858 1 NC_011751.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3695858 sstT 7155732 sstT Escherichia coli UMN026 serine/threonine transporter SstT YP_002414232.1 3694614 D 585056 CDS YP_002414233.1 218706714 7157990 complement(3695863..3696414) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3696414 ygjV 7157990 ygjV Escherichia coli UMN026 hypothetical protein YP_002414233.1 3695863 R 585056 CDS YP_002414234.1 218706715 7159110 complement(3696497..3697984) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme; altronate hydrolase 3697984 uxaA 7159110 uxaA Escherichia coli UMN026 altronate hydrolase YP_002414234.1 3696497 R 585056 CDS YP_002414235.1 218706716 7158203 complement(3697999..3699411) 1 NC_011751.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 3699411 uxaC 7158203 uxaC Escherichia coli UMN026 glucuronate isomerase YP_002414235.1 3697999 R 585056 CDS YP_002414236.1 218706717 7158205 3699774..3701192 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83218546, 98190790; Product type t : transporter; hexuronate transporter 3701192 exuT 7158205 exuT Escherichia coli UMN026 hexuronate transporter YP_002414236.1 3699774 D 585056 CDS YP_002414237.1 218706718 7156292 3701322..3702098 1 NC_011751.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3702098 exuR 7156292 exuR Escherichia coli UMN026 DNA-binding transcriptional repressor ExuR YP_002414237.1 3701322 D 585056 CDS YP_002414238.1 218706719 7156291 3702443..3703105 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3703105 yqjA 7156291 yqjA Escherichia coli UMN026 hypothetical protein YP_002414238.1 3702443 D 585056 CDS YP_002414239.1 218706720 7159628 3703109..3703492 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 3703492 yqjB 7159628 yqjB Escherichia coli UMN026 hypothetical protein YP_002414239.1 3703109 D 585056 CDS YP_002414240.1 218706721 7159629 3703639..3704007 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3704007 yqjC 7159629 yqjC Escherichia coli UMN026 hypothetical protein YP_002414240.1 3703639 D 585056 CDS YP_002414241.1 218706722 7159630 3704045..3704350 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3704350 yqjD 7159630 yqjD Escherichia coli UMN026 hypothetical protein YP_002414241.1 3704045 D 585056 CDS YP_002414242.1 218706723 7159631 3704353..3704757 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3704757 yqjE 7159631 yqjE Escherichia coli UMN026 hypothetical protein YP_002414242.1 3704353 D 585056 CDS YP_002414243.1 218706724 7159632 3704747..3705046 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3705046 yqjK 7159632 yqjK Escherichia coli UMN026 hypothetical protein YP_002414243.1 3704747 D 585056 CDS YP_002414244.1 218706725 7159637 3705233..3705625 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative quinol oxidase subunit 3705625 yqjF 7159637 yqjF Escherichia coli UMN026 putative quinol oxidase subunit YP_002414244.1 3705233 D 585056 CDS YP_002414245.1 218706726 7159633 3705695..3706681 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme; S-transferase 3706681 yqjG 7159633 yqjG Escherichia coli UMN026 S-transferase YP_002414245.1 3705695 D 585056 CDS YP_002414246.1 218706727 7159634 3706973..3707338 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3707338 yhaH 7159634 yhaH Escherichia coli UMN026 hypothetical protein YP_002414246.1 3706973 D 585056 CDS YP_002414247.1 218706728 7159113 3707580..3707936 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3707936 yhaI 7159113 yhaI Escherichia coli UMN026 hypothetical protein YP_002414247.1 3707580 D 585056 CDS YP_002414248.1 218706729 7159114 3708026..3708301 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 3708301 insA 7159114 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002414248.1 3708026 D 585056 CDS YP_002414249.1 218706730 7156814 3708220..3708723 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 3708723 insB 7156814 insB Escherichia coli UMN026 IS1 transposase InsAB'; CP4-6 prophage YP_002414249.1 3708220 D 585056 CDS YP_002414250.1 218706731 7156819 complement(3708764..3709660) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3709660 yhaJ 7156819 yhaJ Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414250.1 3708764 R 585056 CDS YP_002414251.1 218706732 7159115 3709765..3710466 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative pirin-like protein 3710466 yhaK 7159115 yhaK Escherichia coli UMN026 putative pirin-like protein YP_002414251.1 3709765 D 585056 CDS YP_002414252.1 218706733 7159116 3710489..3710653 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3710653 yhaL 7159116 yhaL Escherichia coli UMN026 hypothetical protein YP_002414252.1 3710489 D 585056 CDS YP_002414253.1 218706734 7159117 complement(3710786..3712096) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3712096 yhaM 7159117 yhaM Escherichia coli UMN026 hypothetical protein YP_002414253.1 3710786 R 585056 CDS YP_002414254.1 218706735 7159118 complement(3712124..3713392) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 3713392 yhaO 7159118 yhaO Escherichia coli UMN026 putative transporter YP_002414254.1 3712124 R 585056 CDS YP_002414255.1 218706736 7159119 complement(3713731..3715095) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme; L-serine dehydratase 3 3715095 tdcG 7159119 tdcG Escherichia coli UMN026 L-serine dehydratase 3 YP_002414255.1 3713731 R 585056 CDS YP_002414256.1 218706737 7158041 complement(3715167..3715556) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12777779, 9484901; Product type e : enzyme; hypothetical protein 3715556 tdcF 7158041 tdcF Escherichia coli UMN026 hypothetical protein YP_002414256.1 3715167 R 585056 CDS YP_002414257.1 218706738 7158040 complement(3715570..3717864) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase 3717864 tdcE 7158040 tdcE Escherichia coli UMN026 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase YP_002414257.1 3715570 R 585056 CDS YP_002414258.1 218706739 7158039 complement(3717898..3719118) 1 NC_011751.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 3719118 tdcD 7158039 tdcD Escherichia coli UMN026 propionate/acetate kinase YP_002414258.1 3717898 R 585056 CDS YP_002414259.1 218706740 7158038 complement(3719132..3720463) 1 NC_011751.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3720463 tdcC 7158038 tdcC Escherichia coli UMN026 threonine/serine transporter TdcC YP_002414259.1 3719132 R 585056 CDS YP_002414260.1 218706741 7158037 complement(3720485..3721474) 1 NC_011751.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3721474 tdcB 7158037 tdcB Escherichia coli UMN026 threonine dehydratase YP_002414260.1 3720485 R 585056 CDS YP_002414261.1 218706742 7158036 complement(3721573..3722511) 1 NC_011751.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA 3722511 tdcA 7158036 tdcA Escherichia coli UMN026 DNA-binding transcriptional activator TdcA YP_002414261.1 3721573 R 585056 CDS YP_002414262.1 218706743 7158035 3722688..3723044 1 NC_011751.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3723044 tdcR 7158035 tdcR Escherichia coli UMN026 DNA-binding transcriptional activator TdcR YP_002414262.1 3722688 D 585056 CDS YP_002414263.1 218706744 7158042 3723300..3723839 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3723839 yhaB 7158042 yhaB Escherichia coli UMN026 hypothetical protein YP_002414263.1 3723300 D 585056 CDS YP_002414264.1 218706745 7159111 3723861..3725048 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1705543, 2573820, 2660107, 6351058; hypothetical protein 3725048 yhaC 7159111 yhaC Escherichia coli UMN026 hypothetical protein YP_002414264.1 3723861 D 585056 CDS YP_002414265.1 218706746 7157717 complement(3725565..3726791) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 69151449, 9772162; Product type e : enzyme; glycerate kinase I 3726791 garK 7157717 garK Escherichia coli UMN026 glycerate kinase I YP_002414265.1 3725565 R 585056 CDS YP_002414266.1 218706747 7156506 complement(3726807..3727697) 1 NC_011751.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 3727697 garR 7156506 garR Escherichia coli UMN026 tartronate semialdehyde reductase YP_002414266.1 3726807 R 585056 CDS YP_002414267.1 218706748 7156509 complement(3727727..3728497) 1 NC_011751.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 3728497 garL 7156509 garL Escherichia coli UMN026 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_002414267.1 3727727 R 585056 CDS YP_002414268.1 218706749 7156507 complement(3728513..3729847) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278, 9772162; Product type pt : putative transporter; putative (D)-galactarate transporter 3729847 garP 7156507 garP Escherichia coli UMN026 putative (D)-galactarate transporter YP_002414268.1 3728513 R 585056 CDS YP_002414269.1 218706750 7156508 3730222..3731793 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme; (D)-galactarate dehydrogenase 3731793 garD 7156508 garD Escherichia coli UMN026 (D)-galactarate dehydrogenase YP_002414269.1 3730222 D 585056 CDS YP_002414270.1 218706751 7156505 3731942..3732277 1 NC_011751.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3732277 sohA 7156505 sohA Escherichia coli UMN026 putative regulator PrlF YP_002414270.1 3731942 D 585056 CDS YP_002414271.1 218706752 7157948 3732277..3732741 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3732741 yhaV 7157948 yhaV Escherichia coli UMN026 hypothetical protein YP_002414271.1 3732277 D 585056 CDS YP_002414272.1 218706753 7159120 complement(3732796..3733605) 1 NC_011751.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 3733605 agaR 7159120 agaR Escherichia coli UMN026 DNA-binding transcriptional regulator AgaR YP_002414272.1 3732796 R 585056 CDS YP_002414273.1 218706754 7155713 3733854..3735134 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme; tagatose 6-phosphate aldolase 1, kbaZ subunit 3735134 kbaZ 7155713 kbaZ Escherichia coli UMN026 tagatose 6-phosphate aldolase 1, kbaZ subunit YP_002414273.1 3733854 D 585056 CDS YP_002414274.1 218706755 7156884 3735157..3735630 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3735630 agaV 7156884 agaV Escherichia coli UMN026 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002414274.1 3735157 D 585056 CDS YP_002414275.1 218706756 7155715 3735641..3736420 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIC component of PTS 3736420 7155715 ECUMN_3616 Escherichia coli UMN026 putative enzyme IIC component of PTS YP_002414275.1 3735641 D 585056 CDS YP_002414276.1 218706757 7155359 3736404..3737288 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hexose/hexosamine family PTS permease IID component 3737288 7155359 ECUMN_3617 Escherichia coli UMN026 putative hexose/hexosamine family PTS permease IID component YP_002414276.1 3736404 D 585056 CDS YP_002414277.1 218706758 7155360 3737306..3737740 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme subunit (N-acetyl-galactosamine / galactosamine PTS system enzyme IIA component) 3737740 7155360 ECUMN_3618 Escherichia coli UMN026 putative phosphotransferase system enzyme subunit (N-acetyl-galactosamine / galactosamine PTS system enzyme IIA component) YP_002414277.1 3737306 D 585056 CDS YP_002414278.1 218706759 7155361 3737716..3738870 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-acetylglucosamine-6-phosphate deacetylase 3738870 agaA 7155361 agaA Escherichia coli UMN026 N-acetylglucosamine-6-phosphate deacetylase YP_002414278.1 3737716 D 585056 CDS YP_002414279.1 218706760 7155708 3739220..3740374 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme; tagatose-6-phosphate ketose/aldose isomerase 3740374 agaS 7155708 agaS Escherichia coli UMN026 tagatose-6-phosphate ketose/aldose isomerase YP_002414279.1 3739220 D 585056 CDS YP_002414280.1 218706761 7155714 3740387..3741247 1 NC_011751.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3741247 kbaY 7155714 kbaY Escherichia coli UMN026 tagatose-bisphosphate aldolase YP_002414280.1 3740387 D 585056 CDS YP_002414281.1 218706762 7156883 3741414..3741890 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3741890 agaB 7156883 agaB Escherichia coli UMN026 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002414281.1 3741414 D 585056 CDS YP_002414282.1 218706763 7155709 3741929..3742732 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3742732 agaC 7155709 agaC Escherichia coli UMN026 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_002414282.1 3741929 D 585056 CDS YP_002414283.1 218706764 7155710 3742722..3743513 1 NC_011751.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3743513 agaD 7155710 agaD Escherichia coli UMN026 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_002414283.1 3742722 D 585056 CDS YP_002414284.1 218706765 7155711 3743514..3744281 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme; galactosamine-6-phosphate isomerase 3744281 agaI 7155711 agaI Escherichia coli UMN026 galactosamine-6-phosphate isomerase YP_002414284.1 3743514 D 585056 CDS YP_002414285.1 218706766 7155712 complement(3744331..3745194) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 3745194 yraL 7155712 yraL Escherichia coli UMN026 putative methyltransferase YP_002414285.1 3744331 R 585056 CDS YP_002414286.1 218706767 7159638 3745259..3747295 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3747295 yraM 7159638 yraM Escherichia coli UMN026 hypothetical protein YP_002414286.1 3745259 D 585056 CDS YP_002414287.1 218706768 7159639 3747253..3747648 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3747648 yraN 7159639 yraN Escherichia coli UMN026 hypothetical protein YP_002414287.1 3747253 D 585056 CDS YP_002414288.1 218706769 7159640 3747668..3748258 1 NC_011751.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3748258 yraO 7159640 yraO Escherichia coli UMN026 DnaA initiator-associating protein DiaA YP_002414288.1 3747668 D 585056 CDS YP_002414289.1 218706770 7159641 3748268..3748843 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 3748843 ecfH 7159641 ecfH Escherichia coli UMN026 hypothetical protein YP_002414289.1 3748268 D 585056 CDS YP_002414290.1 218706771 7156223 complement(3748965..3750005) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 3750005 yraQ 7156223 yraQ Escherichia coli UMN026 putative permease YP_002414290.1 3748965 R 585056 CDS YP_002414291.1 218706772 7159642 complement(3750078..3750713) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleoside-diphosphate-sugar epimerase 3750713 yraR 7159642 yraR Escherichia coli UMN026 putative nucleoside-diphosphate-sugar epimerase YP_002414291.1 3750078 R 585056 CDS YP_002414292.1 218706773 7159643 3750841..3751359 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative intracellular protease 3751359 yhbO 7159643 yhbO Escherichia coli UMN026 putative intracellular protease YP_002414292.1 3750841 D 585056 CDS YP_002414293.1 218706774 7159125 complement(3751339..3751782) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3751782 yhbP 7159125 yhbP Escherichia coli UMN026 hypothetical protein YP_002414293.1 3751339 R 585056 CDS YP_002414294.1 218706775 7159126 3751833..3752135 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; GIY-YIG nuclease superfamily protein 3752135 yhbQ 7159126 yhbQ Escherichia coli UMN026 GIY-YIG nuclease superfamily protein YP_002414294.1 3751833 D 585056 CDS YP_002414295.1 218706776 7159127 complement(3752122..3752625) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 3752625 yhbS 7159127 yhbS Escherichia coli UMN026 putative acyltransferase YP_002414295.1 3752122 R 585056 CDS YP_002414296.1 218706777 7159128 complement(3752619..3753143) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative lipid carrier protein 3753143 yhbT 7159128 yhbT Escherichia coli UMN026 putative lipid carrier protein YP_002414296.1 3752619 R 585056 CDS YP_002414297.1 218706778 7159129 3753352..3754347 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; peptidase (collagenase-like) 3754347 yhbU 7159129 yhbU Escherichia coli UMN026 peptidase (collagenase-like) YP_002414297.1 3753352 D 585056 CDS YP_002414298.1 218706779 7159130 3754356..3755234 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; protease 3755234 yhbV 7159130 yhbV Escherichia coli UMN026 protease YP_002414298.1 3754356 D 585056 CDS YP_002414299.1 218706780 7159131 3755315..3756322 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 3756322 yhbW 7159131 yhbW Escherichia coli UMN026 hypothetical protein YP_002414299.1 3755315 D 585056 CDS YP_002414300.1 218706781 7159132 complement(3756300..3757019) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3757019 7159132 ECUMN_3641 Escherichia coli UMN026 hypothetical protein YP_002414300.1 3756300 R 585056 CDS YP_002414301.1 218706782 7155362 3757177..3757707 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pf : putative factor; putative cytoplasmic protein 3757707 7155362 ECUMN_3642 Escherichia coli UMN026 putative cytoplasmic protein YP_002414301.1 3757177 D 585056 CDS YP_002414302.1 218706783 7155363 complement(3757768..3759012) 1 NC_011751.1 tryptophan transporter of high affinity; tryptophan permease 3759012 mtr 7155363 mtr Escherichia coli UMN026 tryptophan permease YP_002414302.1 3757768 R 585056 CDS YP_002414303.1 218706784 7157197 complement(3759166..3761133) 1 NC_011751.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3761133 deaD 7157197 deaD Escherichia coli UMN026 ATP-dependent RNA helicase DeaD YP_002414303.1 3759166 R 585056 CDS YP_002414304.1 218706785 7156133 complement(3761247..3762131) 1 NC_011751.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3762131 nlpI 7156133 nlpI Escherichia coli UMN026 lipoprotein NlpI YP_002414304.1 3761247 R 585056 CDS YP_002414305.1 218706786 7157290 complement(3762240..3764444) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase 3764444 pnp 7157290 pnp Escherichia coli UMN026 polynucleotide phosphorylase/polyadenylase YP_002414305.1 3762240 R 585056 CDS YP_002414306.1 218706787 7157972 complement(3764622..3764891) 1 NC_011751.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3764891 rpsO 7157972 rpsO Escherichia coli UMN026 30S ribosomal protein S15 YP_002414306.1 3764622 R 585056 CDS YP_002414307.1 218706788 7157781 complement(3765040..3765984) 1 NC_011751.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3765984 truB 7157781 truB Escherichia coli UMN026 tRNA pseudouridine synthase B YP_002414307.1 3765040 R 585056 CDS YP_002414308.1 218706789 7158126 complement(3765984..3766385) 1 NC_011751.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3766385 rbfA 7158126 rbfA Escherichia coli UMN026 ribosome-binding factor A YP_002414308.1 3765984 R 585056 CDS YP_002414309.1 218706790 7157620 complement(3766544..3769216) 1 NC_011751.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3769216 infB 7157620 infB Escherichia coli UMN026 translation initiation factor IF-2 YP_002414309.1 3766544 R 585056 CDS YP_002414310.1 218706791 7156812 complement(3769241..3770728) 1 NC_011751.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3770728 nusA 7156812 nusA Escherichia coli UMN026 transcription elongation factor NusA YP_002414310.1 3769241 R 585056 CDS YP_002414311.1 218706792 7157338 complement(3770756..3771208) 1 NC_011751.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3771208 yhbC 7157338 yhbC Escherichia coli UMN026 hypothetical protein YP_002414311.1 3770756 R 585056 CDS YP_002414312.1 218706793 7155622 3771839..3773182 1 NC_011751.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3773182 argG 7155622 argG Escherichia coli UMN026 argininosuccinate synthase YP_002414312.1 3771839 D 585056 CDS YP_002414313.1 218706794 7155773 complement(3773190..3774815) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 3774815 yhbX 7155773 yhbX Escherichia coli UMN026 putative hydrolase YP_002414313.1 3773190 R 585056 CDS YP_002414314.1 218706795 7155621 complement(3775375..3775707) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter; preprotein translocase subunit SecG 3775707 secG 7155621 secG Escherichia coli UMN026 preprotein translocase subunit SecG YP_002414314.1 3775375 R 585056 CDS YP_002414315.1 218706796 7157890 complement(3775935..3777272) 1 NC_011751.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3777272 glmM 7157890 glmM Escherichia coli UMN026 phosphoglucosamine mutase YP_002414315.1 3775935 R 585056 CDS YP_002414316.1 218706797 7156545 complement(3777265..3778113) 1 NC_011751.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3778113 folP 7156545 folP Escherichia coli UMN026 dihydropteroate synthase YP_002414316.1 3777265 R 585056 CDS YP_002414317.1 218706798 7156430 complement(3778203..3780137) 1 NC_011751.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3780137 hflB 7156430 hflB Escherichia coli UMN026 ATP-dependent metalloprotease YP_002414317.1 3778203 R 585056 CDS YP_002414318.1 218706799 7156459 complement(3780237..3780866) 1 NC_011751.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 3780866 rrmJ 7156459 rrmJ Escherichia coli UMN026 23S rRNA methyltransferase J YP_002414318.1 3780237 R 585056 CDS YP_002414319.1 218706800 7157790 3780992..3781285 1 NC_011751.1 RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3781285 yhbY 7157790 yhbY Escherichia coli UMN026 RNA-binding protein YhbY YP_002414319.1 3780992 D 585056 CDS YP_002414320.1 218706801 7159134 complement(3781441..3781917) 1 NC_011751.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3781917 greA 7159134 greA Escherichia coli UMN026 transcription elongation factor GreA YP_002414320.1 3781441 R 585056 CDS YP_002414321.1 218706802 7156609 3782165..3783598 1 NC_011751.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3783598 dacB 7156609 dacB Escherichia coli UMN026 D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_002414321.1 3782165 D 585056 CDS YP_002414322.1 218706803 7156100 complement(3783638..3784810) 1 NC_011751.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3784810 obgE 7156100 obgE Escherichia coli UMN026 GTPase ObgE YP_002414322.1 3783638 R 585056 CDS YP_002414323.1 218706804 7157342 complement(3784826..3785791) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3785791 yhbE 7157342 yhbE Escherichia coli UMN026 hypothetical protein YP_002414323.1 3784826 R 585056 CDS YP_002414324.1 218706805 7159122 complement(3785918..3786175) 1 NC_011751.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3786175 rpmA 7159122 rpmA Escherichia coli UMN026 50S ribosomal protein L27 YP_002414324.1 3785918 R 585056 CDS YP_002414325.1 218706806 7157748 complement(3786196..3786507) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure; 50S ribosomal protein L21 3786507 rplU 7157748 rplU Escherichia coli UMN026 50S ribosomal protein L21 YP_002414325.1 3786196 R 585056 CDS YP_002414326.1 218706807 7157743 3786766..3787737 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme; octaprenyl diphosphate synthase 3787737 ispB 7157743 ispB Escherichia coli UMN026 octaprenyl diphosphate synthase YP_002414326.1 3786766 D 585056 CDS YP_002414327.1 218706808 7156863 3787964..3788242 1 NC_011751.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3788242 sfsB 7156863 sfsB Escherichia coli UMN026 DNA-binding transcriptional regulator Nlp YP_002414327.1 3787964 D 585056 CDS YP_002414328.1 218706809 7157910 complement(3788290..3789549) 1 NC_011751.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3789549 murA 7157910 murA Escherichia coli UMN026 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002414328.1 3788290 R 585056 CDS YP_002414329.1 218706810 7157201 complement(3789604..3789858) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3789858 yrbA 7157201 yrbA Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414329.1 3789604 R 585056 CDS YP_002414330.1 218706811 7159644 complement(3790017..3790310) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3790310 yrbB 7159644 yrbB Escherichia coli UMN026 hypothetical protein YP_002414330.1 3790017 R 585056 CDS YP_002414331.1 218706812 7159645 complement(3790310..3790945) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3790945 yrbC 7159645 yrbC Escherichia coli UMN026 toluene ABC transporter membrane protein YP_002414331.1 3790310 R 585056 CDS YP_002414332.1 218706813 7159646 complement(3790964..3791515) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3791515 yrbD 7159646 yrbD Escherichia coli UMN026 toluene ABC transporter membrane protein YP_002414332.1 3790964 R 585056 CDS YP_002414333.1 218706814 7159647 complement(3791520..3792302) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3792302 yrbE 7159647 yrbE Escherichia coli UMN026 toluene ABC transporter membrane protein YP_002414333.1 3791520 R 585056 CDS YP_002414334.1 218706815 7159648 complement(3792310..3793119) 1 NC_011751.1 ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF 3793119 yrbF 7159648 yrbF Escherichia coli UMN026 putative ABC transporter ATP-binding protein YrbF YP_002414334.1 3792310 R 585056 CDS YP_002414335.1 218706816 7159649 3793329..3794306 1 NC_011751.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3794306 yrbG 7159649 yrbG Escherichia coli UMN026 putative calcium/sodium:proton antiporter YP_002414335.1 3793329 D 585056 CDS YP_002414336.1 218706817 7159650 3794320..3795306 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme; D-arabinose 5-phosphate isomerase 3795306 kdsD 7159650 kdsD Escherichia coli UMN026 D-arabinose 5-phosphate isomerase YP_002414336.1 3794320 D 585056 CDS YP_002414337.1 218706818 7156898 3795327..3795893 1 NC_011751.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3795893 kdsC 7156898 kdsC Escherichia coli UMN026 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002414337.1 3795327 D 585056 CDS YP_002414338.1 218706819 7156897 3795890..3796465 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3796465 yrbK 7156897 yrbK Escherichia coli UMN026 hypothetical protein YP_002414338.1 3795890 D 585056 CDS YP_002414339.1 218706820 7159651 3796434..3796991 1 NC_011751.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3796991 lptA 7159651 lptA Escherichia coli UMN026 lipopolysaccharide transport periplasmic protein LptA YP_002414339.1 3796434 D 585056 CDS YP_002414340.1 218706821 7157007 3796998..3797723 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : putative transporter; putative ABC transporter ATP-binding protein YhbG 3797723 lptB 7157007 lptB Escherichia coli UMN026 putative ABC transporter ATP-binding protein YhbG YP_002414340.1 3796998 D 585056 CDS YP_002414341.1 218706822 7157008 3797771..3799204 1 NC_011751.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3799204 rpoN 7157008 rpoN Escherichia coli UMN026 RNA polymerase factor sigma-54 YP_002414341.1 3797771 D 585056 CDS YP_002414342.1 218706823 7157763 3799227..3799514 1 NC_011751.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3799514 yhbH 7157763 yhbH Escherichia coli UMN026 putative sigma(54) modulation protein YP_002414342.1 3799227 D 585056 CDS YP_002414343.1 218706824 7159123 3799632..3800123 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3800123 ptsN 7159123 ptsN Escherichia coli UMN026 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002414343.1 3799632 D 585056 CDS YP_002414344.1 218706825 7157570 3800169..3801023 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3801023 yhbJ 7157570 yhbJ Escherichia coli UMN026 hypothetical protein YP_002414344.1 3800169 D 585056 CDS YP_002414345.1 218706826 7159124 3801020..3801292 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3801292 npr 7159124 npr Escherichia coli UMN026 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_002414345.1 3801020 D 585056 CDS YP_002414346.1 218706827 7157297 3801505..3802137 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480; hypothetical protein 3802137 yrbL 7157297 yrbL Escherichia coli UMN026 hypothetical protein YP_002414346.1 3801505 D 585056 CDS YP_002414347.1 218706828 7159652 complement(3802134..3802862) 1 NC_011751.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3802862 mtgA 7159652 mtgA Escherichia coli UMN026 monofunctional biosynthetic peptidoglycan transglycosylase YP_002414347.1 3802134 R 585056 CDS YP_002414348.1 218706829 7157190 complement(3802859..3803512) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : putative enzyme; isoprenoid biosynthesis protein 3803512 elbB 7157190 elbB Escherichia coli UMN026 isoprenoid biosynthesis protein YP_002414348.1 3802859 R 585056 CDS YP_002414349.1 218706830 7157854 complement(3803742..3806078) 1 NC_011751.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3806078 arcB 7157854 arcB Escherichia coli UMN026 aerobic respiration control sensor protein ArcB YP_002414349.1 3803742 R 585056 CDS YP_002414350.1 218706831 7155767 complement(3806174..3807103) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Fe-S oxidoreductase 3807103 yhcC 7155767 yhcC Escherichia coli UMN026 putative Fe-S oxidoreductase YP_002414350.1 3806174 R 585056 CDS YP_002414351.1 218706832 7159136 3807686..3812239 1 NC_011751.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3812239 gltB 7159136 gltB Escherichia coli UMN026 glutamate synthase subunit alpha YP_002414351.1 3807686 D 585056 CDS YP_002414352.1 218706833 7156574 3812252..3813670 1 NC_011751.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3813670 gltD 7156574 gltD Escherichia coli UMN026 glutamate synthase subunit beta YP_002414352.1 3812252 D 585056 CDS YP_002414353.1 218706834 7156575 3813854..3814981 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3814981 yhcG 7156575 yhcG Escherichia coli UMN026 hypothetical protein YP_002414353.1 3813854 D 585056 CDS YP_002414354.1 218706835 7159137 complement(3815041..3815505) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3815505 yhcH 7159137 yhcH Escherichia coli UMN026 hypothetical protein YP_002414354.1 3815041 R 585056 CDS YP_002414355.1 218706836 7159138 complement(3815502..3816377) 1 NC_011751.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3816377 nanK 7159138 nanK Escherichia coli UMN026 N-acetylmannosamine kinase YP_002414355.1 3815502 R 585056 CDS YP_002414356.1 218706837 7157236 complement(3816374..3817063) 1 NC_011751.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3817063 nanE 7157236 nanE Escherichia coli UMN026 N-acetylmannosamine-6-phosphate 2-epimerase YP_002414356.1 3816374 R 585056 CDS YP_002414357.1 218706838 7157234 complement(3817111..3818601) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter; putative sialic acid transporter 3818601 nanT 7157234 nanT Escherichia coli UMN026 putative sialic acid transporter YP_002414357.1 3817111 R 585056 CDS YP_002414358.1 218706839 7157239 complement(3818710..3819603) 1 NC_011751.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3819603 nanA 7157239 nanA Escherichia coli UMN026 N-acetylneuraminate lyase YP_002414358.1 3818710 R 585056 CDS YP_002414359.1 218706840 7157233 complement(3819726..3820517) 1 NC_011751.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3820517 nanR 7157233 nanR Escherichia coli UMN026 transcriptional regulator NanR YP_002414359.1 3819726 R 585056 CDS YP_002414360.1 218706841 7157238 3820897..3822264 1 NC_011751.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3822264 dcuD 7157238 dcuD Escherichia coli UMN026 putative cryptic C4-dicarboxylate transporter DcuD YP_002414360.1 3820897 D 585056 CDS YP_002414361.1 218706842 7156121 complement(3822308..3822805) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor; ClpXP protease specificity-enhancing factor 3822805 sspB 7156121 sspB Escherichia coli UMN026 ClpXP protease specificity-enhancing factor YP_002414361.1 3822308 R 585056 CDS YP_002414362.1 218706843 7157987 complement(3822811..3823449) 1 NC_011751.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3823449 sspA 7157987 sspA Escherichia coli UMN026 stringent starvation protein A YP_002414362.1 3822811 R 585056 CDS YP_002414363.1 218706844 7157986 complement(3823844..3824236) 1 NC_011751.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3824236 rpsI 7157986 rpsI Escherichia coli UMN026 30S ribosomal protein S9 YP_002414363.1 3823844 R 585056 CDS YP_002414364.1 218706845 7157775 complement(3824252..3824680) 1 NC_011751.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3824680 rplM 7157775 rplM Escherichia coli UMN026 50S ribosomal protein L13 YP_002414364.1 3824252 R 585056 CDS YP_002414365.1 218706846 7157735 complement(3824899..3826026) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3826026 yhcM 7157735 yhcM Escherichia coli UMN026 hypothetical protein YP_002414365.1 3824899 R 585056 CDS YP_002414366.1 218706847 7159139 3826220..3826618 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : putative enzyme; cytochrome d ubiquinol oxidase subunit III 3826618 yhcB 7159139 yhcB Escherichia coli UMN026 cytochrome d ubiquinol oxidase subunit III YP_002414366.1 3826220 D 585056 CDS YP_002414367.1 218706848 7159135 3826772..3828139 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme; serine endoprotease 3828139 degQ 7159135 degQ Escherichia coli UMN026 serine endoprotease YP_002414367.1 3826772 D 585056 CDS YP_002414368.1 218706849 7156138 3828229..3829296 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme; serine endoprotease 3829296 degS 7156138 degS Escherichia coli UMN026 serine endoprotease YP_002414368.1 3828229 D 585056 CDS YP_002414369.1 218706850 7156139 complement(3829359..3830297) 1 NC_011751.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3830297 mdh 7156139 mdh Escherichia coli UMN026 malate dehydrogenase YP_002414369.1 3829359 R 585056 CDS YP_002414370.1 218706851 7157069 3830732..3831202 1 NC_011751.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3831202 argR 7157069 argR Escherichia coli UMN026 arginine repressor YP_002414370.1 3830732 D 585056 CDS YP_002414371.1 218706852 7155779 3831567..3831830 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3831830 yhcN 7155779 yhcN Escherichia coli UMN026 hypothetical protein YP_002414371.1 3831567 D 585056 CDS YP_002414372.1 218706853 7159140 complement(3831886..3832158) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative barnase inhibitor 3832158 yhcO 7159140 yhcO Escherichia coli UMN026 putative barnase inhibitor YP_002414372.1 3831886 R 585056 CDS YP_002414373.1 218706854 7159141 complement(3832250..3834217) 1 NC_011751.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3834217 aaeB 7159141 aaeB Escherichia coli UMN026 p-hydroxybenzoic acid efflux subunit AaeB YP_002414373.1 3832250 R 585056 CDS YP_002414374.1 218706855 7155657 complement(3834223..3835155) 1 NC_011751.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3835155 aaeA 7155657 aaeA Escherichia coli UMN026 p-hydroxybenzoic acid efflux subunit AaeA YP_002414374.1 3834223 R 585056 CDS YP_002414375.1 218706856 7155656 complement(3835163..3835366) 1 NC_011751.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3835366 aaeX 7155656 aaeX Escherichia coli UMN026 hypothetical protein YP_002414375.1 3835163 R 585056 CDS YP_002414376.1 218706857 7155659 3835549..3836478 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator; putative DNA-binding transcriptional regulator 3836478 aaeR 7155659 aaeR Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414376.1 3835549 D 585056 CDS YP_002414377.1 218706858 7155658 complement(3836606..3838051) 1 NC_011751.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3838051 tldD 7155658 tldD Escherichia coli UMN026 protease TldD YP_002414377.1 3836606 R 585056 CDS YP_002414378.1 218706859 7158076 complement(3838207..3842007) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : putative membrane component; hypothetical protein 3842007 yhdP 7158076 yhdP Escherichia coli UMN026 hypothetical protein YP_002414378.1 3838207 R 585056 CDS YP_002414379.1 218706860 7159147 complement(3842075..3843544) 1 NC_011751.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3843544 rng 7159147 rng Escherichia coli UMN026 ribonuclease G YP_002414379.1 3842075 R 585056 CDS YP_002414380.1 218706861 7157712 complement(3843534..3844127) 1 NC_011751.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3844127 yhdE 7157712 yhdE Escherichia coli UMN026 Maf-like protein YP_002414380.1 3843534 R 585056 CDS YP_002414381.1 218706862 7159142 complement(3844136..3844624) 1 NC_011751.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3844624 mreD 7159142 mreD Escherichia coli UMN026 rod shape-determining protein MreD YP_002414381.1 3844136 R 585056 CDS YP_002414382.1 218706863 7157181 complement(3844624..3845640) 1 NC_011751.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3845640 mreC 7157181 mreC Escherichia coli UMN026 rod shape-determining protein MreC YP_002414382.1 3844624 R 585056 CDS YP_002414383.1 218706864 7157180 complement(3845706..3846749) 1 NC_011751.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3846749 mreB 7157180 mreB Escherichia coli UMN026 rod shape-determining protein MreB YP_002414383.1 3845706 R 585056 CDS YP_002414384.1 218706865 7157179 3846857..3847045 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3847045 7157179 ECUMN_3725 Escherichia coli UMN026 hypothetical protein YP_002414384.1 3846857 D 585056 CDS YP_002414385.1 218706866 7155364 complement(3847054..3848994) 1 NC_011751.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3848994 csrD 7155364 csrD Escherichia coli UMN026 regulatory protein CsrD YP_002414385.1 3847054 R 585056 CDS YP_002414386.1 218706867 7156046 3849146..3850120 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 3850120 yhdH 7156046 yhdH Escherichia coli UMN026 putative oxidoreductase YP_002414386.1 3849146 D 585056 CDS YP_002414387.1 218706868 7159143 3850157..3850987 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3850987 7159143 ECUMN_3728 Escherichia coli UMN026 hypothetical protein YP_002414387.1 3850157 D 585056 CDS YP_002414388.1 218706869 7155365 3851853..3852323 1 NC_011751.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3852323 accB 7155365 accB Escherichia coli UMN026 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002414388.1 3851853 D 585056 CDS YP_002414389.1 218706870 7155672 3852334..3853683 1 NC_011751.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3853683 accC 7155672 accC Escherichia coli UMN026 acetyl-CoA carboxylase biotin carboxylase subunit YP_002414389.1 3852334 D 585056 CDS YP_002414390.1 218706871 7155673 3853792..3854034 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3854034 yhdT 7155673 yhdT Escherichia coli UMN026 hypothetical protein YP_002414390.1 3853792 D 585056 CDS YP_002414391.1 218706872 7159148 3854024..3855475 1 NC_011751.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3855475 panF 7159148 panF Escherichia coli UMN026 sodium/panthothenate symporter YP_002414391.1 3854024 D 585056 CDS YP_002414392.1 218706873 7157381 3855487..3856368 1 NC_011751.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3856368 prmA 7157381 prmA Escherichia coli UMN026 ribosomal protein L11 methyltransferase YP_002414392.1 3855487 D 585056 CDS YP_002414393.1 218706874 7157527 3856697..3857662 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme; tRNA -dihydrouridine synthase B 3857662 dusB 7157527 dusB Escherichia coli UMN026 tRNA -dihydrouridine synthase B YP_002414393.1 3856697 D 585056 CDS YP_002414394.1 218706875 7156212 3857688..3857984 1 NC_011751.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3857984 fis 7156212 fis Escherichia coli UMN026 DNA-binding protein Fis YP_002414394.1 3857688 D 585056 CDS YP_002414395.1 218706876 7156366 3858070..3858954 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme; putative methyltransferase 3858954 yhdJ 7156366 yhdJ Escherichia coli UMN026 putative methyltransferase YP_002414395.1 3858070 D 585056 CDS YP_002414396.1 218706877 7159144 3859038..3859217 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3859217 yhdU 7159144 yhdU Escherichia coli UMN026 hypothetical protein YP_002414396.1 3859038 D 585056 CDS YP_002414397.1 218706878 7159149 complement(3859220..3859882) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8203018, 11257026, 8407802, 1720861; Product type r : regulator; DNA-binding transcriptional regulator EnvR 3859882 envR 7159149 envR Escherichia coli UMN026 DNA-binding transcriptional regulator EnvR YP_002414397.1 3859220 R 585056 CDS YP_002414398.1 218706879 7156255 3860281..3861438 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein; cytoplasmic membrane lipoprotein 3861438 acrE 7156255 acrE Escherichia coli UMN026 cytoplasmic membrane lipoprotein YP_002414398.1 3860281 D 585056 CDS YP_002414399.1 218706880 7155690 3861450..3864554 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter; multidrug efflux system protein 3864554 acrF 7155690 acrF Escherichia coli UMN026 multidrug efflux system protein YP_002414399.1 3861450 D 585056 CDS YP_002414400.1 218706881 7155691 3864807..3865028 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3865028 yhdV 7155691 yhdV Escherichia coli UMN026 hypothetical protein YP_002414400.1 3864807 D 585056 CDS YP_002414401.1 218706882 7159150 3865254..3865430 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3865430 7159150 ECUMN_3742 Escherichia coli UMN026 hypothetical protein YP_002414401.1 3865254 D 585056 CDS YP_002414402.1 218706883 7155366 3865567..3866484 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter periplasmic-binding protein 3866484 aapJ 7155366 aapJ Escherichia coli UMN026 amino-acid ABC transporter periplasmic-binding protein YP_002414402.1 3865567 D 585056 CDS YP_002414403.1 218706884 7155660 3866552..3867733 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3867733 aapQ 7155660 aapQ Escherichia coli UMN026 amino-acid ABC transporter membrane protein YP_002414403.1 3866552 D 585056 CDS YP_002414404.1 218706885 7155663 3867743..3868846 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3868846 aapM 7155663 aapM Escherichia coli UMN026 amino-acid ABC transporter membrane protein YP_002414404.1 3867743 D 585056 CDS YP_002414405.1 218706886 7155661 3868854..3869612 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter; amino-acid ABC transporter ATP-binding protein 3869612 aapP 7155661 aapP Escherichia coli UMN026 amino-acid ABC transporter ATP-binding protein YP_002414405.1 3868854 D 585056 CDS YP_002414406.1 218706887 7154983 3875168..3876049 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3876049 yrdA 7154983 yrdA Escherichia coli UMN026 hypothetical protein YP_002414406.1 3875168 D 585056 CDS YP_002414407.1 218706888 7159653 complement(3876025..3876282) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3876282 yrdB 7159653 yrdB Escherichia coli UMN026 hypothetical protein YP_002414407.1 3876025 R 585056 CDS YP_002414408.1 218706889 7159654 complement(3876279..3877097) 1 NC_011751.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3877097 aroE 7159654 aroE Escherichia coli UMN026 shikimate 5-dehydrogenase YP_002414408.1 3876279 R 585056 CDS YP_002414409.1 218706890 7155787 complement(3877102..3877674) 1 NC_011751.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor 3877674 yrdC 7155787 yrdC Escherichia coli UMN026 putative ribosome maturation factor YP_002414409.1 3877102 R 585056 CDS YP_002414410.1 218706891 7159655 complement(3877679..3878221) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative DNA topoisomerase 3878221 yrdD 7159655 yrdD Escherichia coli UMN026 putative DNA topoisomerase YP_002414410.1 3877679 R 585056 CDS YP_002414411.1 218706892 7159656 complement(3878250..3878723) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722; hypothetical protein 3878723 smg 7159656 smg Escherichia coli UMN026 hypothetical protein YP_002414411.1 3878250 R 585056 CDS YP_002414412.1 218706893 7157941 complement(3878695..3879819) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722; DNA protecting protein DprA 3879819 smf 7157941 smf Escherichia coli UMN026 DNA protecting protein DprA YP_002414412.1 3878695 R 585056 CDS YP_002414413.1 218706894 7157940 3879949..3880458 1 NC_011751.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3880458 def 7157940 def Escherichia coli UMN026 peptide deformylase YP_002414413.1 3879949 D 585056 CDS YP_002414414.1 218706895 7156136 3880473..3881420 1 NC_011751.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3881420 fmt 7156136 fmt Escherichia coli UMN026 methionyl-tRNA formyltransferase YP_002414414.1 3880473 D 585056 CDS YP_002414415.1 218706896 7156419 3881466..3882755 1 NC_011751.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3882755 rsmB 7156419 rsmB Escherichia coli UMN026 16S rRNA methyltransferase B YP_002414415.1 3881466 D 585056 CDS YP_002414416.1 218706897 7157797 3882777..3884153 1 NC_011751.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3884153 trkA 7157797 trkA Escherichia coli UMN026 potassium transporter peripheral membrane component YP_002414416.1 3882777 D 585056 CDS YP_002414417.1 218706898 7158108 3884283..3884693 1 NC_011751.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3884693 mscL 7158108 mscL Escherichia coli UMN026 large-conductance mechanosensitive channel YP_002414417.1 3884283 D 585056 CDS YP_002414418.1 218706899 7157185 complement(3884690..3884908) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3884908 yhdL 7157185 yhdL Escherichia coli UMN026 hypothetical protein YP_002414418.1 3884690 R 585056 CDS YP_002414419.1 218706900 7159145 complement(3884964..3885389) 1 NC_011751.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3885389 zntR 7159145 zntR Escherichia coli UMN026 zinc-responsive transcriptional regulator YP_002414419.1 3884964 R 585056 CDS YP_002414420.1 218706901 7159688 complement(3885400..3885768) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3885768 yhdN 7159688 yhdN Escherichia coli UMN026 hypothetical protein YP_002414420.1 3885400 R 585056 CDS YP_002414421.1 218706902 7159146 complement(3885875..3886258) 1 NC_011751.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3886258 rplQ 7159146 rplQ Escherichia coli UMN026 50S ribosomal protein L17 YP_002414421.1 3885875 R 585056 CDS YP_002414422.1 218706903 7157739 complement(3886299..3887288) 1 NC_011751.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3887288 rpoA 7157739 rpoA Escherichia coli UMN026 DNA-directed RNA polymerase subunit alpha YP_002414422.1 3886299 R 585056 CDS YP_002414423.1 218706904 7157757 complement(3887314..3887934) 1 NC_011751.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3887934 rpsD 7157757 rpsD Escherichia coli UMN026 30S ribosomal protein S4 YP_002414423.1 3887314 R 585056 CDS YP_002414424.1 218706905 7157770 complement(3887968..3888357) 1 NC_011751.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3888357 rpsK 7157770 rpsK Escherichia coli UMN026 30S ribosomal protein S11 YP_002414424.1 3887968 R 585056 CDS YP_002414425.1 218706906 7157777 complement(3888374..3888730) 1 NC_011751.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3888730 rpsM 7157777 rpsM Escherichia coli UMN026 30S ribosomal protein S13 YP_002414425.1 3888374 R 585056 CDS YP_002414426.1 218706907 7157779 complement(3889025..3890356) 1 NC_011751.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3890356 secY 7157779 secY Escherichia coli UMN026 preprotein translocase subunit SecY YP_002414426.1 3889025 R 585056 CDS YP_002414427.1 218706908 7157892 complement(3890364..3890798) 1 NC_011751.1 late assembly protein; 50S ribosomal protein L15 3890798 rplO 7157892 rplO Escherichia coli UMN026 50S ribosomal protein L15 YP_002414427.1 3890364 R 585056 CDS YP_002414428.1 218706909 7157737 complement(3890802..3890981) 1 NC_011751.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3890981 rpmD 7157737 rpmD Escherichia coli UMN026 50S ribosomal protein L30 YP_002414428.1 3890802 R 585056 CDS YP_002414429.1 218706910 7157751 complement(3890985..3891488) 1 NC_011751.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3891488 rpsE 7157751 rpsE Escherichia coli UMN026 30S ribosomal protein S5 YP_002414429.1 3890985 R 585056 CDS YP_002414430.1 218706911 7157771 complement(3891503..3891856) 1 NC_011751.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3891856 rplR 7157771 rplR Escherichia coli UMN026 50S ribosomal protein L18 YP_002414430.1 3891503 R 585056 CDS YP_002414431.1 218706912 7157740 complement(3891866..3892399) 1 NC_011751.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3892399 rplF 7157740 rplF Escherichia coli UMN026 50S ribosomal protein L6 YP_002414431.1 3891866 R 585056 CDS YP_002414432.1 218706913 7157730 complement(3892412..3892804) 1 NC_011751.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3892804 rpsH 7157730 rpsH Escherichia coli UMN026 30S ribosomal protein S8 YP_002414432.1 3892412 R 585056 CDS YP_002414433.1 218706914 7157774 complement(3892838..3893143) 1 NC_011751.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3893143 rpsN 7157774 rpsN Escherichia coli UMN026 30S ribosomal protein S14 YP_002414433.1 3892838 R 585056 CDS YP_002414434.1 218706915 7157780 complement(3893158..3893697) 1 NC_011751.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3893697 rplE 7157780 rplE Escherichia coli UMN026 50S ribosomal protein L5 YP_002414434.1 3893158 R 585056 CDS YP_002414435.1 218706916 7157729 complement(3893712..3894026) 1 NC_011751.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3894026 rplX 7157729 rplX Escherichia coli UMN026 50S ribosomal protein L24 YP_002414435.1 3893712 R 585056 CDS YP_002414436.1 218706917 7157746 complement(3894037..3894408) 1 NC_011751.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3894408 rplN 7157746 rplN Escherichia coli UMN026 50S ribosomal protein L14 YP_002414436.1 3894037 R 585056 CDS YP_002414437.1 218706918 7157736 complement(3894573..3894827) 1 NC_011751.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3894827 rpsQ 7157736 rpsQ Escherichia coli UMN026 30S ribosomal protein S17 YP_002414437.1 3894573 R 585056 CDS YP_002414438.1 218706919 7157783 complement(3894827..3895018) 1 NC_011751.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3895018 rpmC 7157783 rpmC Escherichia coli UMN026 50S ribosomal protein L29 YP_002414438.1 3894827 R 585056 CDS YP_002414439.1 218706920 7157750 complement(3895018..3895428) 1 NC_011751.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3895428 rplP 7157750 rplP Escherichia coli UMN026 50S ribosomal protein L16 YP_002414439.1 3895018 R 585056 CDS YP_002414440.1 218706921 7157738 complement(3895441..3896142) 1 NC_011751.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3896142 rpsC 7157738 rpsC Escherichia coli UMN026 30S ribosomal protein S3 YP_002414440.1 3895441 R 585056 CDS YP_002414441.1 218706922 7157769 complement(3896160..3896492) 1 NC_011751.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3896492 rplV 7157769 rplV Escherichia coli UMN026 50S ribosomal protein L22 YP_002414441.1 3896160 R 585056 CDS YP_002414442.1 218706923 7157744 complement(3896507..3896785) 1 NC_011751.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3896785 rpsS 7157744 rpsS Escherichia coli UMN026 30S ribosomal protein S19 YP_002414442.1 3896507 R 585056 CDS YP_002414443.1 218706924 7157785 complement(3896802..3897623) 1 NC_011751.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3897623 rplB 7157785 rplB Escherichia coli UMN026 50S ribosomal protein L2 YP_002414443.1 3896802 R 585056 CDS YP_002414444.1 218706925 7157726 complement(3897641..3897943) 1 NC_011751.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3897943 rplW 7157726 rplW Escherichia coli UMN026 50S ribosomal protein L23 YP_002414444.1 3897641 R 585056 CDS YP_002414445.1 218706926 7157745 complement(3897940..3898545) 1 NC_011751.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3898545 rplD 7157745 rplD Escherichia coli UMN026 50S ribosomal protein L4 YP_002414445.1 3897940 R 585056 CDS YP_002414446.1 218706927 7157728 complement(3898556..3899185) 1 NC_011751.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3899185 rplC 7157728 rplC Escherichia coli UMN026 50S ribosomal protein L3 YP_002414446.1 3898556 R 585056 CDS YP_002414447.1 218706928 7157727 complement(3899218..3899529) 1 NC_011751.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3899529 rpsJ 7157727 rpsJ Escherichia coli UMN026 30S ribosomal protein S10 YP_002414447.1 3899218 R 585056 CDS YP_002414448.1 218706929 7157776 complement(3899658..3899819) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3899819 7157776 ECUMN_3795 Escherichia coli UMN026 hypothetical protein YP_002414448.1 3899658 R 585056 CDS YP_002414449.1 218706930 7155367 3899908..3900375 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative bifunctional prepilin peptidase HopD 3900375 7155367 ECUMN_3796 Escherichia coli UMN026 putative bifunctional prepilin peptidase HopD YP_002414449.1 3899908 D 585056 CDS YP_002414450.1 218706931 7155368 complement(3900372..3900848) 1 NC_011751.1 iron storage protein; bacterioferritin 3900848 bfr 7155368 bfr Escherichia coli UMN026 bacterioferritin YP_002414450.1 3900372 R 585056 CDS YP_002414451.1 218706932 7155872 complement(3900921..3901115) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8954950, 9889981, 2661540, 8639572; Product type c : carrier; bacterioferritin-associated ferredoxin 3901115 bfd 7155872 bfd Escherichia coli UMN026 bacterioferritin-associated ferredoxin YP_002414451.1 3900921 R 585056 CDS YP_002414452.1 218706933 7155871 complement(3901298..3902482) 1 NC_011751.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3902482 tufA 7155871 tufA Escherichia coli UMN026 elongation factor Tu YP_002414452.1 3901298 R 585056 CDS YP_002414453.1 218706934 7158139 complement(3902553..3904667) 1 NC_011751.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3904667 fusA 7158139 fusA Escherichia coli UMN026 elongation factor G YP_002414453.1 3902553 R 585056 CDS YP_002414454.1 218706935 7156480 complement(3904764..3905234) 1 NC_011751.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3905234 rpsG 7156480 rpsG Escherichia coli UMN026 30S ribosomal protein S7 YP_002414454.1 3904764 R 585056 CDS YP_002414455.1 218706936 7157773 complement(3905331..3905705) 1 NC_011751.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3905705 rpsL 7157773 rpsL Escherichia coli UMN026 30S ribosomal protein S12 YP_002414455.1 3905331 R 585056 CDS YP_002414456.1 218706937 7157778 complement(3905831..3906118) 1 NC_011751.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3906118 tusB 7157778 tusB Escherichia coli UMN026 sulfur transfer complex subunit TusB YP_002414456.1 3905831 R 585056 CDS YP_002414457.1 218706938 7158143 complement(3906126..3906485) 1 NC_011751.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3906485 tusC 7158143 tusC Escherichia coli UMN026 sulfur relay protein TusC YP_002414457.1 3906126 R 585056 CDS YP_002414458.1 218706939 7158144 complement(3906485..3906871) 1 NC_011751.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3906871 tusD 7158144 tusD Escherichia coli UMN026 sulfur transfer complex subunit TusD YP_002414458.1 3906485 R 585056 CDS YP_002414459.1 218706940 7158145 complement(3906871..3907593) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3907593 yheO 7158145 yheO Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414459.1 3906871 R 585056 CDS YP_002414460.1 218706941 7159151 complement(3907760..3908572) 1 NC_011751.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3908572 fkpA 7159151 fkpA Escherichia coli UMN026 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002414460.1 3907760 R 585056 CDS YP_002414461.1 218706942 7156373 3908793..3909011 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3909011 slyX 7156373 slyX Escherichia coli UMN026 hypothetical protein YP_002414461.1 3908793 D 585056 CDS YP_002414462.1 218706943 7157939 complement(3909060..3909650) 1 NC_011751.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3909650 slyD 7157939 slyD Escherichia coli UMN026 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002414462.1 3909060 R 585056 CDS YP_002414463.1 218706944 7157938 complement(3909745..3909945) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3909945 yheV 7157938 yheV Escherichia coli UMN026 hypothetical protein YP_002414463.1 3909745 R 585056 CDS YP_002414464.1 218706945 7159155 complement(3909955..3911760) 1 NC_011751.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3911760 kefB 7159155 kefB Escherichia coli UMN026 glutathione-regulated potassium-efflux system protein KefB YP_002414464.1 3909955 R 585056 CDS YP_002414465.1 218706946 7156903 complement(3911760..3912314) 1 NC_011751.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3912314 kefG 7156903 kefG Escherichia coli UMN026 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002414465.1 3911760 R 585056 CDS YP_002414466.1 218706947 7156906 3912442..3914355 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter ATP-binding protein 3914355 yheS 7156906 yheS Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002414466.1 3912442 D 585056 CDS YP_002414467.1 218706948 7159152 3914355..3915377 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : putative enzyme; putative hydrolase 3915377 yheT 7159152 yheT Escherichia coli UMN026 putative hydrolase YP_002414467.1 3914355 D 585056 CDS YP_002414468.1 218706949 7159153 3915371..3915589 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3915589 yheU 7159153 yheU Escherichia coli UMN026 hypothetical protein YP_002414468.1 3915371 D 585056 CDS YP_002414469.1 218706950 7159154 3915643..3916512 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme; phosphoribulokinase 3916512 prkB 7159154 prkB Escherichia coli UMN026 phosphoribulokinase YP_002414469.1 3915643 D 585056 CDS YP_002414470.1 218706951 7157525 complement(3916567..3916971) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3916971 yhfA 7157525 yhfA Escherichia coli UMN026 hypothetical protein YP_002414470.1 3916567 R 585056 CDS YP_002414471.1 218706952 7156018 3917051..3917266 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3917266 7156018 ECUMN_3819 Escherichia coli UMN026 hypothetical protein YP_002414471.1 3917051 D 585056 CDS YP_002414472.1 218706953 7155369 3917273..3917905 1 NC_011751.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3917905 crp 7155369 crp Escherichia coli UMN026 cAMP-regulatory protein YP_002414472.1 3917273 D 585056 CDS YP_002414473.1 218706954 7156017 3917944..3920046 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3920046 yhfK 7156017 yhfK Escherichia coli UMN026 hypothetical protein YP_002414473.1 3917944 D 585056 CDS YP_002414474.1 218706955 7159158 complement(3920113..3921333) 1 NC_011751.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 3921333 argD 7159158 argD Escherichia coli UMN026 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_002414474.1 3920113 R 585056 CDS YP_002414475.1 218706956 7155771 complement(3921419..3921982) 1 NC_011751.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3921982 pabA 7155771 pabA Escherichia coli UMN026 para-aminobenzoate synthase component II YP_002414475.1 3921419 R 585056 CDS YP_002414476.1 218706957 7157373 complement(3922014..3922616) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process; cell filamentation protein Fic 3922616 fic 7157373 fic Escherichia coli UMN026 cell filamentation protein Fic YP_002414476.1 3922014 R 585056 CDS YP_002414477.1 218706958 7156352 complement(3922606..3922773) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3922773 yhfG 7156352 yhfG Escherichia coli UMN026 hypothetical protein YP_002414477.1 3922606 R 585056 CDS YP_002414478.1 218706959 7159157 complement(3922878..3923450) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase A 3923450 ppiA 7159157 ppiA Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase A YP_002414478.1 3922878 R 585056 CDS YP_002414479.1 218706960 7157505 3923721..3924902 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20509826; Product type pt : putative transporter; hypothetical protein 3924902 tsgA 7157505 tsgA Escherichia coli UMN026 hypothetical protein YP_002414479.1 3923721 D 585056 CDS YP_002414480.1 218706961 7158133 3925164..3927707 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme; nitrite reductase, large subunit, NAD(P) H-binding 3927707 nirB 7158133 nirB Escherichia coli UMN026 nitrite reductase, large subunit, NAD(P) H-binding YP_002414480.1 3925164 D 585056 CDS YP_002414481.1 218706962 7157282 3927704..3928030 1 NC_011751.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3928030 nirD 7157282 nirD Escherichia coli UMN026 nitrite reductase small subunit YP_002414481.1 3927704 D 585056 CDS YP_002414482.1 218706963 7157284 3928156..3928962 1 NC_011751.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3928962 nirC 7157284 nirC Escherichia coli UMN026 nitrite transporter NirC YP_002414482.1 3928156 D 585056 CDS YP_002414483.1 218706964 7157283 3928981..3930354 1 NC_011751.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3930354 cysG 7157283 cysG Escherichia coli UMN026 siroheme synthase YP_002414483.1 3928981 D 585056 CDS YP_002414484.1 218706965 7156083 3930606..3930773 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3930773 yhfL 7156083 yhfL Escherichia coli UMN026 hypothetical protein YP_002414484.1 3930606 D 585056 CDS YP_002414485.1 218706966 7159159 complement(3930880..3931965) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3931965 yhfS 7159159 yhfS Escherichia coli UMN026 hypothetical protein YP_002414485.1 3930880 R 585056 CDS YP_002414486.1 218706967 7159160 complement(3931977..3933281) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3933281 yhfT 7159160 yhfT Escherichia coli UMN026 hypothetical protein YP_002414486.1 3931977 R 585056 CDS YP_002414487.1 218706968 7159161 complement(3933293..3933646) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3933646 yhfU 7159161 yhfU Escherichia coli UMN026 hypothetical protein YP_002414487.1 3933293 R 585056 CDS YP_002414488.1 218706969 7159162 complement(3933657..3934535) 1 NC_011751.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase 3934535 php 7159162 php Escherichia coli UMN026 putative hydrolase YP_002414488.1 3933657 R 585056 CDS YP_002414489.1 218706970 7157463 complement(3934532..3935758) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mutase 3935758 yhfW 7157463 yhfW Escherichia coli UMN026 putative mutase YP_002414489.1 3934532 R 585056 CDS YP_002414490.1 218706971 7159163 complement(3935758..3936921) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative amino acid racemase 3936921 yhfX 7159163 yhfX Escherichia coli UMN026 putative amino acid racemase YP_002414490.1 3935758 R 585056 CDS YP_002414491.1 218706972 7159164 complement(3937005..3937367) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3937367 yhfY 7159164 yhfY Escherichia coli UMN026 hypothetical protein YP_002414491.1 3937005 R 585056 CDS YP_002414492.1 218706973 7159165 complement(3937384..3938289) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3938289 yhfZ 7159165 yhfZ Escherichia coli UMN026 hypothetical protein YP_002414492.1 3937384 R 585056 CDS YP_002414493.1 218706974 7159166 complement(3938449..3939453) 1 NC_011751.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3939453 trpS 7159166 trpS Escherichia coli UMN026 tryptophanyl-tRNA synthetase YP_002414493.1 3938449 R 585056 CDS YP_002414494.1 218706975 7158124 complement(3939446..3940204) 1 NC_011751.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3940204 gph 7158124 gph Escherichia coli UMN026 phosphoglycolate phosphatase YP_002414494.1 3939446 R 585056 CDS YP_002414495.1 218706976 7156603 complement(3940197..3940874) 1 NC_011751.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3940874 rpe 7156603 rpe Escherichia coli UMN026 ribulose-phosphate 3-epimerase YP_002414495.1 3940197 R 585056 CDS YP_002414496.1 218706977 7157722 complement(3940892..3941728) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme; DNA adenine methylase 3941728 dam 7157722 dam Escherichia coli UMN026 DNA adenine methylase YP_002414496.1 3940892 R 585056 CDS YP_002414497.1 218706978 7156105 complement(3941835..3943121) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3943121 damX 7156105 damX Escherichia coli UMN026 hypothetical protein YP_002414497.1 3941835 R 585056 CDS YP_002414498.1 218706979 7156106 complement(3943213..3944301) 1 NC_011751.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3944301 aroB 7156106 aroB Escherichia coli UMN026 3-dehydroquinate synthase YP_002414498.1 3943213 R 585056 CDS YP_002414499.1 218706980 7155784 complement(3944358..3944879) 1 NC_011751.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3944879 aroK 7155784 aroK Escherichia coli UMN026 shikimate kinase I YP_002414499.1 3944358 R 585056 CDS YP_002414500.1 218706981 7155791 complement(3945280..3946518) 1 NC_011751.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3946518 hofQ 7155791 hofQ Escherichia coli UMN026 outer membrane porin HofQ YP_002414500.1 3945280 R 585056 CDS YP_002414501.1 218706982 7156693 complement(3946430..3946834) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3946834 yrfA 7156693 yrfA Escherichia coli UMN026 hypothetical protein YP_002414501.1 3946430 R 585056 CDS YP_002414502.1 218706983 7159657 complement(3946824..3947264) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 3947264 yrfB 7159657 yrfB Escherichia coli UMN026 hypothetical protein YP_002414502.1 3946824 R 585056 CDS YP_002414503.1 218706984 7159658 complement(3947248..3947787) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial assembly protein (pilN-like) 3947787 yrfC 7159658 yrfC Escherichia coli UMN026 putative fimbrial assembly protein (pilN-like) YP_002414503.1 3947248 R 585056 CDS YP_002414504.1 218706985 7159659 complement(3947787..3948566) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative pilus assembly protein 3948566 yrfD 7159659 yrfD Escherichia coli UMN026 putative pilus assembly protein YP_002414504.1 3947787 R 585056 CDS YP_002414505.1 218706986 7159660 3948686..3951238 1 NC_011751.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3951238 mrcA 7159660 mrcA Escherichia coli UMN026 peptidoglycan synthetase YP_002414505.1 3948686 D 585056 CDS YP_002414506.1 218706987 7157175 complement(3951406..3951966) 1 NC_011751.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3951966 nudE 7157175 nudE Escherichia coli UMN026 ADP-ribose diphosphatase NudE YP_002414506.1 3951406 R 585056 CDS YP_002414507.1 218706988 7157319 3952286..3954421 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator; intracellular growth attenuator protein 3954421 igaA 7157319 igaA Escherichia coli UMN026 intracellular growth attenuator protein YP_002414507.1 3952286 D 585056 CDS YP_002414508.1 218706989 7156793 3954486..3955154 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative hydrolase 3955154 yrfG 7156793 yrfG Escherichia coli UMN026 putative hydrolase YP_002414508.1 3954486 D 585056 CDS YP_002414509.1 218706990 7159661 3955165..3955566 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor; ribosome-associated heat shock protein Hsp15 3955566 hslR 7159661 hslR Escherichia coli UMN026 ribosome-associated heat shock protein Hsp15 YP_002414509.1 3955165 D 585056 CDS YP_002414510.1 218706991 7156722 3955591..3956469 1 NC_011751.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3956469 hslO 7156722 hslO Escherichia coli UMN026 Hsp33-like chaperonin YP_002414510.1 3955591 D 585056 CDS YP_002414511.1 218706992 7156721 complement(3956532..3958256) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20223645; Product type pm : putative membrane component; hypothetical protein 3958256 yhgE 7156721 yhgE Escherichia coli UMN026 hypothetical protein YP_002414511.1 3956532 R 585056 CDS YP_002414512.1 218706993 7159168 complement(3958332..3958463) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 3958463 7159168 ECUMN_3861 Escherichia coli UMN026 hypothetical protein YP_002414512.1 3958332 R 585056 CDS YP_002414513.1 218706994 7155370 3958635..3960257 1 NC_011751.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3960257 pck 7155370 pck Escherichia coli UMN026 phosphoenolpyruvate carboxykinase YP_002414513.1 3958635 D 585056 CDS YP_002414514.1 218706995 7157396 complement(3960333..3961685) 1 NC_011751.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3961685 envZ 7157396 envZ Escherichia coli UMN026 osmolarity sensor protein YP_002414514.1 3960333 R 585056 CDS YP_002414515.1 218706996 7156257 complement(3961682..3962401) 1 NC_011751.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3962401 ompR 7156257 ompR Escherichia coli UMN026 osmolarity response regulator YP_002414515.1 3961682 R 585056 CDS YP_002414516.1 218706997 7157349 3962629..3963105 1 NC_011751.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3963105 greB 7157349 greB Escherichia coli UMN026 transcription elongation factor GreB YP_002414516.1 3962629 D 585056 CDS YP_002414517.1 218706998 7156610 3963202..3965523 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor; transcriptional accessory protein 3965523 yhgF 7156610 yhgF Escherichia coli UMN026 transcriptional accessory protein YP_002414517.1 3963202 D 585056 CDS YP_002414518.1 218706999 7159169 3965980..3966207 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter; ferrous iron transport protein A 3966207 feoA 7159169 feoA Escherichia coli UMN026 ferrous iron transport protein A YP_002414518.1 3965980 D 585056 CDS YP_002414519.1 218707000 7156331 3966224..3968545 1 NC_011751.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3968545 feoB 7156331 feoB Escherichia coli UMN026 ferrous iron transport protein B YP_002414519.1 3966224 D 585056 CDS YP_002414520.1 218707001 7156332 3968545..3968781 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 3968781 yhgG 7156332 yhgG Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414520.1 3968545 D 585056 CDS YP_002414521.1 218707002 7159170 3968983..3969876 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2678009; Product type ph : phenotype; hypothetical protein 3969876 yhgA 7159170 yhgA Escherichia coli UMN026 hypothetical protein YP_002414521.1 3968983 D 585056 CDS YP_002414522.1 218707003 7159167 complement(3970096..3970866) 1 NC_011751.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3970866 bioH 7159167 bioH Escherichia coli UMN026 carboxylesterase BioH YP_002414522.1 3970096 R 585056 CDS YP_002414523.1 218707004 7155881 3970904..3971587 1 NC_011751.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3971587 gntX 7155881 gntX Escherichia coli UMN026 gluconate periplasmic binding protein YP_002414523.1 3970904 D 585056 CDS YP_002414524.1 218707005 7156600 3971646..3972221 1 NC_011751.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3972221 gntY 7156600 gntY Escherichia coli UMN026 putative DNA uptake protein YP_002414524.1 3971646 D 585056 CDS YP_002414525.1 218707006 7156601 3972582..3973898 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter; gluconate transporter 3973898 gntT 7156601 gntT Escherichia coli UMN026 gluconate transporter YP_002414525.1 3972582 D 585056 CDS YP_002414526.1 218707007 7156598 complement(3973946..3976027) 1 NC_011751.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3976027 malQ 7156598 malQ Escherichia coli UMN026 4-alpha-glucanotransferase YP_002414526.1 3973946 R 585056 CDS YP_002414527.1 218707008 7157048 complement(3976037..3978430) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme; maltodextrin phosphorylase 3978430 malP 7157048 malP Escherichia coli UMN026 maltodextrin phosphorylase YP_002414527.1 3976037 R 585056 CDS YP_002414528.1 218707009 7157047 3979053..3981758 1 NC_011751.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3981758 malT 7157047 malT Escherichia coli UMN026 transcriptional regulator MalT YP_002414528.1 3979053 D 585056 CDS YP_002414529.1 218707010 7157050 complement(3981801..3982817) 1 NC_011751.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3982817 rtcA 7157050 rtcA Escherichia coli UMN026 RNA 3'-terminal-phosphate cyclase YP_002414529.1 3981801 R 585056 CDS YP_002414530.1 218707011 7157812 complement(3982821..3984047) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023; hypothetical protein 3984047 rtcB 7157812 rtcB Escherichia coli UMN026 hypothetical protein YP_002414530.1 3982821 R 585056 CDS YP_002414531.1 218707012 7157813 3984236..3985834 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9738023, 3045764, 7920643, 7984428; Product type r : regulator; sigma 54-dependent transcriptional regulator of rtcBA expression 3985834 rtcR 7157813 rtcR Escherichia coli UMN026 sigma 54-dependent transcriptional regulator of rtcBA expression YP_002414531.1 3984236 D 585056 CDS YP_002414532.1 218707013 7157814 complement(3985816..3986574) 1 NC_011751.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3986574 glpR 7157814 glpR Escherichia coli UMN026 DNA-binding transcriptional repressor GlpR YP_002414532.1 3985816 R 585056 CDS YP_002414533.1 218707014 7156570 complement(3986591..3987421) 1 NC_011751.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3987421 glpG 7156570 glpG Escherichia coli UMN026 intramembrane serine protease GlpG YP_002414533.1 3986591 R 585056 CDS YP_002414534.1 218707015 7156567 complement(3987466..3987792) 1 NC_011751.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3987792 glpE 7156567 glpE Escherichia coli UMN026 thiosulfate sulfurtransferase YP_002414534.1 3987466 R 585056 CDS YP_002414535.1 218707016 7156565 3987982..3989487 1 NC_011751.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3989487 glpD 7156565 glpD Escherichia coli UMN026 glycerol-3-phosphate dehydrogenase YP_002414535.1 3987982 D 585056 CDS YP_002414536.1 218707017 7156564 complement(3989994..3991145) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial adhesin 3991145 7156564 ECUMN_3885 Escherichia coli UMN026 putative fimbrial adhesin YP_002414536.1 3989994 R 585056 CDS YP_002414537.1 218707018 7155371 complement(3991138..3991941) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative periplasmic pilin chaperone 3991941 7155371 ECUMN_3886 Escherichia coli UMN026 putative periplasmic pilin chaperone YP_002414537.1 3991138 R 585056 CDS YP_002414538.1 218707019 7155372 complement(3991883..3992407) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative exported fimbrial-like adhesin protein 3992407 7155372 ECUMN_3887 Escherichia coli UMN026 putative exported fimbrial-like adhesin protein YP_002414538.1 3991883 R 585056 CDS YP_002414539.1 218707020 7155373 complement(3992415..3992987) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure; putative fimbrial minor structural subunit 3992987 7155373 ECUMN_3888 Escherichia coli UMN026 putative fimbrial minor structural subunit YP_002414539.1 3992415 R 585056 CDS YP_002414540.1 218707021 7155374 complement(3992978..3995569) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor; putative outer membrane export usher protein AufC 3995569 aufC 7155374 aufC Escherichia coli UMN026 putative outer membrane export usher protein AufC YP_002414540.1 3992978 R 585056 CDS YP_002414541.1 218707022 7155843 complement(3995611..3996363) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor; putative fimbria chaperone protein 3996363 7155843 ECUMN_3890 Escherichia coli UMN026 putative fimbria chaperone protein YP_002414541.1 3995611 R 585056 CDS YP_002414542.1 218707023 7155375 complement(3996484..3997188) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15213132; Product type s : structure; Auf fimbriae major fimbrial subunit AufA 3997188 aufA 7155375 aufA Escherichia coli UMN026 Auf fimbriae major fimbrial subunit AufA YP_002414542.1 3996484 R 585056 CDS YP_002414543.1 218707024 7155842 complement(3997672..4000119) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme; glycogen phosphorylase 4000119 glgP 7155842 glgP Escherichia coli UMN026 glycogen phosphorylase YP_002414543.1 3997672 R 585056 CDS YP_002414544.1 218707025 7156540 complement(4000138..4001571) 1 NC_011751.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4001571 glgA 7156540 glgA Escherichia coli UMN026 glycogen synthase YP_002414544.1 4000138 R 585056 CDS YP_002414545.1 218707026 7156537 complement(4001571..4002866) 1 NC_011751.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4002866 glgC 7156537 glgC Escherichia coli UMN026 glucose-1-phosphate adenylyltransferase YP_002414545.1 4001571 R 585056 CDS YP_002414546.1 218707027 7156539 complement(4002884..4004857) 1 NC_011751.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme 4004857 glgX 7156539 glgX Escherichia coli UMN026 glycogen debranching enzyme YP_002414546.1 4002884 R 585056 CDS YP_002414547.1 218707028 7156542 complement(4004854..4007040) 1 NC_011751.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 4007040 glgB 7156542 glgB Escherichia coli UMN026 glycogen branching enzyme YP_002414547.1 4004854 R 585056 CDS YP_002414548.1 218707029 7156538 complement(4007313..4008416) 1 NC_011751.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4008416 asd 7156538 asd Escherichia coli UMN026 aspartate-semialdehyde dehydrogenase YP_002414548.1 4007313 R 585056 CDS YP_002414549.1 218707030 7155809 4008608..4009201 1 NC_011751.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 4009201 yhgN 7155809 yhgN Escherichia coli UMN026 putative dITP- and XTP- hydrolase YP_002414549.1 4008608 D 585056 CDS YP_002414550.1 218707031 7159171 complement(4009258..4010598) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter; low affinity gluconate transporter 4010598 gntU 7159171 gntU Escherichia coli UMN026 low affinity gluconate transporter YP_002414550.1 4009258 R 585056 CDS YP_002414551.1 218707032 7156599 complement(4010602..4011129) 1 NC_011751.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 4011129 gntK 7156599 gntK Escherichia coli UMN026 gluconate kinase 1 YP_002414551.1 4010602 R 585056 CDS YP_002414552.1 218707033 7156595 complement(4011268..4012263) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator; DNA-binding transcriptional repressor 4012263 gntR 7156595 gntR Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002414552.1 4011268 R 585056 CDS YP_002414553.1 218707034 7156597 complement(4012487..4013182) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4013182 yhhW 7156597 yhhW Escherichia coli UMN026 hypothetical protein YP_002414553.1 4012487 R 585056 CDS YP_002414554.1 218707035 7159187 complement(4013305..4014342) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : putative enzyme; putative dehydrogenase 4014342 yhhX 7159187 yhhX Escherichia coli UMN026 putative dehydrogenase YP_002414554.1 4013305 R 585056 CDS YP_002414555.1 218707036 7159188 complement(4014376..4014561) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4014561 7159188 ECUMN_3904 Escherichia coli UMN026 hypothetical protein YP_002414555.1 4014376 R 585056 CDS YP_002414556.1 218707037 7157855 4014677..4015165 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 4015165 yhhY 7157855 yhhY Escherichia coli UMN026 putative acetyltransferase YP_002414556.1 4014677 D 585056 CDS YP_002414557.1 218707038 7159189 4015401..4016579 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4016579 yhhZ 7159189 yhhZ Escherichia coli UMN026 hypothetical protein YP_002414557.1 4015401 D 585056 CDS YP_002414558.1 218707039 7159190 4016576..4017070 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4017070 yrhA 7159190 yrhA Escherichia coli UMN026 hypothetical protein YP_002414558.1 4016576 D 585056 CDS YP_002414559.1 218707040 7159662 4017520..4017804 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4017804 yrhB 7159662 yrhB Escherichia coli UMN026 hypothetical protein YP_002414559.1 4017520 D 585056 CDS YP_002414560.1 218707041 7159663 complement(4017842..4019584) 1 NC_011751.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 4019584 ggt 7159663 ggt Escherichia coli UMN026 gamma-glutamyltranspeptidase YP_002414560.1 4017842 R 585056 CDS YP_002414561.1 218707042 7156527 4019704..4020144 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4020144 yhhA 7156527 yhhA Escherichia coli UMN026 hypothetical protein YP_002414561.1 4019704 D 585056 CDS YP_002414562.1 218707043 7159172 complement(4020131..4020874) 1 NC_011751.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 4020874 ugpQ 7159172 ugpQ Escherichia coli UMN026 cytoplasmic glycerophosphodiester phosphodiesterase YP_002414562.1 4020131 R 585056 CDS YP_002414563.1 218707044 7158169 complement(4020871..4021941) 1 NC_011751.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 4021941 ugpC 7158169 ugpC Escherichia coli UMN026 glycerol-3-phosphate transporter ATP-binding subunit YP_002414563.1 4020871 R 585056 CDS YP_002414564.1 218707045 7158167 complement(4021943..4022788) 1 NC_011751.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4022788 ugpE 7158167 ugpE Escherichia coli UMN026 glycerol-3-phosphate transporter membrane protein YP_002414564.1 4021943 R 585056 CDS YP_002414565.1 218707046 7158168 complement(4022785..4023672) 1 NC_011751.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4023672 ugpA 7158168 ugpA Escherichia coli UMN026 glycerol-3-phosphate transporter permease YP_002414565.1 4022785 R 585056 CDS YP_002414566.1 218707047 7158165 complement(4023770..4025086) 1 NC_011751.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 4025086 ugpB 7158165 ugpB Escherichia coli UMN026 glycerol-3-phosphate transporter periplasmic binding protein YP_002414566.1 4023770 R 585056 CDS YP_002414567.1 218707048 7158166 complement(4025484..4026197) 1 NC_011751.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4026197 livF 7158166 livF Escherichia coli UMN026 leucine/isoleucine/valine transporter ATP-binding subunit YP_002414567.1 4025484 R 585056 CDS YP_002414568.1 218707049 7156984 complement(4026199..4026966) 1 NC_011751.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 4026966 livG 7156984 livG Escherichia coli UMN026 leucine/isoleucine/valine transporter ATP-binding subunit YP_002414568.1 4026199 R 585056 CDS YP_002414569.1 218707050 7156985 complement(4026963..4028240) 1 NC_011751.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine permease 4028240 livM 7156985 livM Escherichia coli UMN026 leucine/isoleucine/valine permease YP_002414569.1 4026963 R 585056 CDS YP_002414570.1 218707051 7156989 complement(4028237..4029163) 1 NC_011751.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid permease LivH 4029163 livH 7156989 livH Escherichia coli UMN026 branched-chain amino acid permease LivH YP_002414570.1 4028237 R 585056 CDS YP_002414571.1 218707052 7156986 complement(4029211..4030320) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter; leucine ABC transporter periplasmic-binding protein 4030320 livK 7156986 livK Escherichia coli UMN026 leucine ABC transporter periplasmic-binding protein YP_002414571.1 4029211 R 585056 CDS YP_002414572.1 218707053 7156988 4030744..4031127 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4031127 yhhK 7156988 yhhK Escherichia coli UMN026 hypothetical protein YP_002414572.1 4030744 D 585056 CDS YP_002414573.1 218707054 7159181 complement(4031327..4032430) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter; leucine/isoleucine/valine ABC transporter periplasmic-binding protein 4032430 livJ 7159181 livJ Escherichia coli UMN026 leucine/isoleucine/valine ABC transporter periplasmic-binding protein YP_002414573.1 4031327 R 585056 CDS YP_002414574.1 218707055 7156987 complement(4032702..4033556) 1 NC_011751.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4033556 rpoH 7156987 rpoH Escherichia coli UMN026 RNA polymerase factor sigma-32 YP_002414574.1 4032702 R 585056 CDS YP_002414575.1 218707056 7157762 complement(4033801..4034859) 1 NC_011751.1 putative ABC transporter, membrane protein; cell division protein FtsX 4034859 ftsX 7157762 ftsX Escherichia coli UMN026 cell division protein FtsX YP_002414575.1 4033801 R 585056 CDS YP_002414576.1 218707057 7156466 complement(4034852..4035520) 1 NC_011751.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4035520 ftsE 7156466 ftsE Escherichia coli UMN026 cell division protein FtsE YP_002414576.1 4034852 R 585056 CDS YP_002414577.1 218707058 7156458 complement(4035523..4037019) 1 NC_011751.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 4037019 ftsY 7156458 ftsY Escherichia coli UMN026 cell division protein FtsY YP_002414577.1 4035523 R 585056 CDS YP_002414578.1 218707059 7156467 4037169..4037765 1 NC_011751.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4037765 rsmD 7156467 rsmD Escherichia coli UMN026 16S rRNA m(2)G966-methyltransferase YP_002414578.1 4037169 D 585056 CDS YP_002414579.1 218707060 7159173 4037632..4038024 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4038024 7159173 ECUMN_3928 Escherichia coli UMN026 hypothetical protein YP_002414579.1 4037632 D 585056 CDS YP_002414580.1 218707061 7155377 complement(4038027..4038386) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4038386 yhhM 7155377 yhhM Escherichia coli UMN026 hypothetical protein YP_002414580.1 4038027 R 585056 CDS YP_002414581.1 218707062 7159182 4038527..4039153 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4039153 yhhN 7159182 yhhN Escherichia coli UMN026 hypothetical protein YP_002414581.1 4038527 D 585056 CDS YP_002414582.1 218707063 7159183 4039227..4041425 1 NC_011751.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4041425 zntA 7159183 zntA Escherichia coli UMN026 zinc/cadmium/mercury/lead-transporting ATPase YP_002414582.1 4039227 D 585056 CDS YP_002414583.1 218707064 7159687 complement(4041458..4041766) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4041766 7159687 ECUMN_3932 Escherichia coli UMN026 hypothetical protein YP_002414583.1 4041458 R 585056 CDS YP_002414584.1 218707065 7155378 complement(4041981..4042226) 1 NC_011751.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4042226 tusA 7155378 tusA Escherichia coli UMN026 sulfur transfer protein SirA YP_002414584.1 4041981 R 585056 CDS YP_002414585.1 218707066 7158142 4042447..4043112 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4043112 yhhQ 7158142 yhhQ Escherichia coli UMN026 hypothetical protein YP_002414585.1 4042447 D 585056 CDS YP_002414586.1 218707067 7159184 4043185..4043742 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter; hypothetical protein 4043742 dcrB 7159184 dcrB Escherichia coli UMN026 hypothetical protein YP_002414586.1 4043185 D 585056 CDS YP_002414587.1 218707068 7156116 complement(4043746..4044963) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; major facilitator superfamily transporter 4044963 yhhS 7156116 yhhS Escherichia coli UMN026 major facilitator superfamily transporter YP_002414587.1 4043746 R 585056 CDS YP_002414588.1 218707069 7159185 4045095..4046144 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4046144 yhhT 7159185 yhhT Escherichia coli UMN026 hypothetical protein YP_002414588.1 4045095 D 585056 CDS YP_002414589.1 218707070 7159186 4046524..4046913 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4046913 7159186 ECUMN_3938 Escherichia coli UMN026 putative lipoprotein YP_002414589.1 4046524 D 585056 CDS YP_002414590.1 218707071 7155379 4046973..4048040 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase 4048040 7155379 ECUMN_3939 Escherichia coli UMN026 putative methyltransferase YP_002414590.1 4046973 D 585056 CDS YP_002414591.1 218707072 7155380 4048057..4048803 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4048803 7155380 ECUMN_3940 Escherichia coli UMN026 hypothetical protein YP_002414591.1 4048057 D 585056 CDS YP_002414592.1 218707073 7155381 4048782..4049621 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 1-acylglycerol-3-phosphate O-acyltransferase 4049621 7155381 ECUMN_3941 Escherichia coli UMN026 putative 1-acylglycerol-3-phosphate O-acyltransferase YP_002414592.1 4048782 D 585056 CDS YP_002414593.1 218707074 7155382 4049596..4049853 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative acyl carrier protein 4049853 7155382 ECUMN_3942 Escherichia coli UMN026 putative acyl carrier protein YP_002414593.1 4049596 D 585056 CDS YP_002414594.1 218707075 7155383 4049865..4050116 1 NC_011751.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 4050116 7155383 ECUMN_3943 Escherichia coli UMN026 acyl carrier protein YP_002414594.1 4049865 D 585056 CDS YP_002414595.1 218707076 7155384 4050121..4050702 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 4050702 7155384 ECUMN_3944 Escherichia coli UMN026 hypothetical protein YP_002414595.1 4050121 D 585056 CDS YP_002414596.1 218707077 7155385 4050660..4052060 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fatty acid degradation enzyme 4052060 7155385 ECUMN_3945 Escherichia coli UMN026 putative fatty acid degradation enzyme YP_002414596.1 4050660 D 585056 CDS YP_002414597.1 218707078 7155386 4052017..4052400 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative fatty acid degradation enzyme 4052400 7155386 ECUMN_3946 Escherichia coli UMN026 putative fatty acid degradation enzyme YP_002414597.1 4052017 D 585056 CDS YP_002414598.1 218707079 7155387 4052391..4054067 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 4054067 7155387 ECUMN_3947 Escherichia coli UMN026 putative acyltransferase YP_002414598.1 4052391 D 585056 CDS YP_002414599.1 218707080 7155388 4054071..4054493 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative thioesterase 4054493 7155388 ECUMN_3948 Escherichia coli UMN026 putative thioesterase YP_002414599.1 4054071 D 585056 CDS YP_002414600.1 218707081 7155389 4054490..4055095 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative outer membrane lipoprotein carrier protein 4055095 7155389 ECUMN_3949 Escherichia coli UMN026 putative outer membrane lipoprotein carrier protein YP_002414600.1 4054490 D 585056 CDS YP_002414601.1 218707082 7155390 4055064..4057382 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4057382 7155390 ECUMN_3950 Escherichia coli UMN026 putative transporter YP_002414601.1 4055064 D 585056 CDS YP_002414602.1 218707083 7155391 4057379..4057963 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4057963 7155391 ECUMN_3951 Escherichia coli UMN026 putative lipoprotein YP_002414602.1 4057379 D 585056 CDS YP_002414603.1 218707084 7155392 4057956..4059134 1 NC_011751.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase I 4059134 7155392 ECUMN_3952 Escherichia coli UMN026 3-oxoacyl-(acyl carrier protein) synthase I YP_002414603.1 4057956 D 585056 CDS YP_002414604.1 218707085 7155393 4059131..4059595 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase 4059595 7155393 ECUMN_3953 Escherichia coli UMN026 putative 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase YP_002414604.1 4059131 D 585056 CDS YP_002414605.1 218707086 7155394 4059595..4060326 1 NC_011751.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-(acyl-carrier-protein) reductase 4060326 fabG 7155394 fabG Escherichia coli UMN026 3-ketoacyl-(acyl-carrier-protein) reductase YP_002414605.1 4059595 D 585056 CDS YP_002414606.1 218707087 7155395 4060323..4061552 1 NC_011751.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 4061552 7155395 ECUMN_3955 Escherichia coli UMN026 3-oxoacyl-(acyl carrier protein) synthase II YP_002414606.1 4060323 D 585056 CDS YP_002414607.1 218707088 7155396 4061554..4062141 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20092861, 10625633, 8939709; Product type e : enzyme; holo-(acyl carrier protein) synthase 2 4062141 acpT 7155396 acpT Escherichia coli UMN026 holo-(acyl carrier protein) synthase 2 YP_002414607.1 4061554 D 585056 CDS YP_002414608.1 218707089 7155686 4062252..4063826 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12960164, 7934931, 92077434, 7867647; Product type t : transporter; nickel ABC transporter periplasmic-binding protein 4063826 nikA 7155686 nikA Escherichia coli UMN026 nickel ABC transporter periplasmic-binding protein YP_002414608.1 4062252 D 585056 CDS YP_002414609.1 218707090 7157275 4063826..4064770 1 NC_011751.1 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4064770 nikB 7157275 nikB Escherichia coli UMN026 nickel transporter permease NikB YP_002414609.1 4063826 D 585056 CDS YP_002414610.1 218707091 7157276 4064767..4065600 1 NC_011751.1 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4065600 nikC 7157276 nikC Escherichia coli UMN026 nickel transporter permease NikC YP_002414610.1 4064767 D 585056 CDS YP_002414611.1 218707092 7157277 4065600..4066364 1 NC_011751.1 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4066364 nikD 7157277 nikD Escherichia coli UMN026 nickel transporter ATP-binding protein NikD YP_002414611.1 4065600 D 585056 CDS YP_002414612.1 218707093 7157278 4066361..4067167 1 NC_011751.1 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4067167 nikE 7157278 nikE Escherichia coli UMN026 nickel transporter ATP-binding protein NikE YP_002414612.1 4066361 D 585056 CDS YP_002414613.1 218707094 7157279 4067172..4067573 1 NC_011751.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4067573 nikR 7157279 nikR Escherichia coli UMN026 nickel responsive regulator YP_002414613.1 4067172 D 585056 CDS YP_002414614.1 218707095 7157280 4067763..4068518 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4068518 7157280 ECUMN_3963 Escherichia coli UMN026 putative transcriptional regulator YP_002414614.1 4067763 D 585056 CDS YP_002414615.1 218707096 7155397 4068531..4069016 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme subunit IIA 4069016 7155397 ECUMN_3964 Escherichia coli UMN026 putative phosphotransferase system enzyme subunit IIA YP_002414615.1 4068531 D 585056 CDS YP_002414616.1 218707097 7155398 4069013..4069294 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphotransferase system enzyme IIB 4069294 7155398 ECUMN_3965 Escherichia coli UMN026 putative phosphotransferase system enzyme IIB YP_002414616.1 4069013 D 585056 CDS YP_002414617.1 218707098 7155399 4069341..4070729 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase system permease IIC 4070729 7155399 ECUMN_3966 Escherichia coli UMN026 putative phosphotransferase system permease IIC YP_002414617.1 4069341 D 585056 CDS YP_002414618.1 218707099 7155400 4070722..4072230 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative carbohydrate kinase 4072230 7155400 ECUMN_3967 Escherichia coli UMN026 putative carbohydrate kinase YP_002414618.1 4070722 D 585056 CDS YP_002414619.1 218707100 7155401 4072220..4072489 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system 4072489 7155401 ECUMN_3968 Escherichia coli UMN026 putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system YP_002414619.1 4072220 D 585056 CDS YP_002414620.1 218707101 7155402 4072520..4073371 1 NC_011751.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; putative fructose-1,6-bisphosphate aldolase 4073371 gatY 7155402 gatY Escherichia coli UMN026 putative fructose-1,6-bisphosphate aldolase YP_002414620.1 4072520 D 585056 CDS YP_002414621.1 218707102 7155403 complement(4073462..4074586) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative ABC transporter membrane protein 4074586 yhhJ 7155403 yhhJ Escherichia coli UMN026 putative ABC transporter membrane protein YP_002414621.1 4073462 R 585056 CDS YP_002414622.1 218707103 7159180 complement(4074586..4077321) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme; fused ribosome-associated ATPase/membrane protein 4077321 rbbA 7159180 rbbA Escherichia coli UMN026 fused ribosome-associated ATPase/membrane protein YP_002414622.1 4074586 R 585056 CDS YP_002414623.1 218707104 7157619 complement(4077318..4078385) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative HlyD family secretion protein 4078385 yhiI 7157619 yhiI Escherichia coli UMN026 putative HlyD family secretion protein YP_002414623.1 4077318 R 585056 CDS YP_002414624.1 218707105 7159193 complement(4078751..4080373) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4080373 yhiJ 7159193 yhiJ Escherichia coli UMN026 hypothetical protein YP_002414624.1 4078751 R 585056 CDS YP_002414625.1 218707106 7159194 complement(4080635..4082308) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4082308 7159194 ECUMN_3974 Escherichia coli UMN026 hypothetical protein YP_002414625.1 4080635 R 585056 CDS YP_002414626.1 218707107 7155404 complement(4082199..4082408) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4082408 7155404 ECUMN_3975 Escherichia coli UMN026 hypothetical protein YP_002414626.1 4082199 R 585056 CDS YP_002414627.1 218707108 7155405 4082607..4083659 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4083659 yhiM 7155405 yhiM Escherichia coli UMN026 hypothetical protein YP_002414627.1 4082607 D 585056 CDS YP_002414628.1 218707109 7159195 complement(4083974..4085176) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 4085176 yhiN 7159195 yhiN Escherichia coli UMN026 putative oxidoreductase YP_002414628.1 4083974 R 585056 CDS YP_002414629.1 218707110 7159196 4085408..4086907 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter; phosphate transporter, low-affinity 4086907 pitA 7159196 pitA Escherichia coli UMN026 phosphate transporter, low-affinity YP_002414629.1 4085408 D 585056 CDS YP_002414630.1 218707111 7157468 complement(4086978..4087313) 1 NC_011751.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4087313 yhiO 7157468 yhiO Escherichia coli UMN026 universal stress protein UspB YP_002414630.1 4086978 R 585056 CDS YP_002414631.1 218707112 7159197 4087704..4088138 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor; universal stress global response regulator 4088138 uspA 7159197 uspA Escherichia coli UMN026 universal stress global response regulator YP_002414631.1 4087704 D 585056 CDS YP_002414632.1 218707113 7158193 4088454..4089923 1 NC_011751.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4089923 yhiP 7158193 yhiP Escherichia coli UMN026 inner membrane transporter YhiP YP_002414632.1 4088454 D 585056 CDS YP_002414633.1 218707114 7159198 complement(4089972..4090724) 1 NC_011751.1 predicted SAM-dependent methyltransferase; putative methyltransferase 4090724 yhiQ 7159198 yhiQ Escherichia coli UMN026 putative methyltransferase YP_002414633.1 4089972 R 585056 CDS YP_002414634.1 218707115 7159199 complement(4090732..4092774) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme; oligopeptidase A 4092774 prlC 7159199 prlC Escherichia coli UMN026 oligopeptidase A YP_002414634.1 4090732 R 585056 CDS YP_002414635.1 218707116 7157526 4092977..4093819 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : putative enzyme; putative DNA (exogenous) processing protein 4093819 yhiR 7157526 yhiR Escherichia coli UMN026 putative DNA (exogenous) processing protein YP_002414635.1 4092977 D 585056 CDS YP_002414636.1 218707117 7159200 4093891..4095243 1 NC_011751.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4095243 gor 7159200 gor Escherichia coli UMN026 glutathione reductase YP_002414636.1 4093891 D 585056 CDS YP_002414637.1 218707118 7156602 4095402..4095581 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4095581 7156602 ECUMN_3987 Escherichia coli UMN026 hypothetical protein YP_002414637.1 4095402 D 585056 CDS YP_002414638.1 218707119 7155406 4096120..4096473 1 NC_011751.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 4096473 arsR 7155406 arsR Escherichia coli UMN026 DNA-binding transcriptional repressor ArsR YP_002414638.1 4096120 D 585056 CDS YP_002414639.1 218707120 7155800 4096521..4096883 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8674982; Product type r : regulator; Arsenical resistance operon trans-acting repressor 4096883 arsD 7155800 arsD Escherichia coli UMN026 Arsenical resistance operon trans-acting repressor YP_002414639.1 4096521 D 585056 CDS YP_002414640.1 218707121 7155799 4096877..4098652 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8674982; Product type e : enzyme; Arsenical pump-driving ATPase 4098652 arsA 7155799 arsA Escherichia coli UMN026 Arsenical pump-driving ATPase YP_002414640.1 4096877 D 585056 CDS YP_002414641.1 218707122 7155796 4098695..4099984 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter; arsenite/antimonite transporter 4099984 arsB 7155796 arsB Escherichia coli UMN026 arsenite/antimonite transporter YP_002414641.1 4098695 D 585056 CDS YP_002414642.1 218707123 7155797 4099997..4100422 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme; arsenate reductase 4100422 arsC 7155797 arsC Escherichia coli UMN026 arsenate reductase YP_002414642.1 4099997 D 585056 CDS YP_002414643.1 218707124 7155798 complement(4100556..4100852) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4100852 7155798 ECUMN_3994 Escherichia coli UMN026 hypothetical protein YP_002414643.1 4100556 R 585056 CDS YP_002414644.1 218707125 7155407 4100948..4101961 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; hypothetical protein 4101961 7155407 ECUMN_3995 Escherichia coli UMN026 hypothetical protein YP_002414644.1 4100948 D 585056 CDS YP_002414645.1 218707126 7155408 4102542..4103765 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4103765 7155408 ECUMN_3996 Escherichia coli UMN026 hypothetical protein YP_002414645.1 4102542 D 585056 CDS YP_002414646.1 218707127 7155409 4104010..4104576 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein; outer membrane lipoprotein 4104576 slp 7155409 slp Escherichia coli UMN026 outer membrane lipoprotein YP_002414646.1 4104010 D 585056 CDS YP_002414647.1 218707128 7157934 4104729..4105259 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4105259 yhiF 7157934 yhiF Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414647.1 4104729 D 585056 CDS YP_002414648.1 218707129 7159192 complement(4105320..4106348) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16275907; Product type e : enzyme; Heme oxygenase 4106348 chuS 7159192 chuS Escherichia coli UMN026 Heme oxygenase YP_002414648.1 4105320 R 585056 CDS YP_002414649.1 218707130 7155958 complement(4106397..4108379) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11179376, 7768795, 9393841, 9680204, 9157252; Product type t : transporter; outer membrane hemin receptor 4108379 chuA 7155958 chuA Escherichia coli UMN026 outer membrane hemin receptor YP_002414649.1 4106397 R 585056 CDS YP_002414650.1 218707131 7155957 4108985..4109977 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7768795, 9393841, 9680204; Product type pt : putative transporter; putative periplasmic binding protein 4109977 chuT 7155957 chuT Escherichia coli UMN026 putative periplasmic binding protein YP_002414650.1 4108985 D 585056 CDS YP_002414651.1 218707132 7155959 4109997..4111334 1 NC_011751.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4111334 7155959 ECUMN_4003 Escherichia coli UMN026 coproporphyrinogen III oxidase YP_002414651.1 4109997 D 585056 CDS YP_002414652.1 218707133 7155410 4111347..4111841 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4111841 7155410 ECUMN_4004 Escherichia coli UMN026 hypothetical protein YP_002414652.1 4111347 D 585056 CDS YP_002414653.1 218707134 7155411 4111841..4112464 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4112464 7155411 ECUMN_4005 Escherichia coli UMN026 hypothetical protein YP_002414653.1 4111841 D 585056 CDS YP_002414654.1 218707135 7155412 4112513..4113505 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative hemin transport system permease 4113505 chuU 7155412 chuU Escherichia coli UMN026 putative hemin transport system permease YP_002414654.1 4112513 D 585056 CDS YP_002414655.1 218707136 7155960 4113349..4114272 1 NC_011751.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4114272 hmuV 7155960 hmuV Escherichia coli UMN026 hemin importer ATP-binding subunit YP_002414655.1 4113349 D 585056 CDS YP_002414656.1 218707137 7155961 complement(4114324..4114971) 1 NC_011751.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase 4114971 yhiD 7155961 yhiD Escherichia coli UMN026 putative Mg(2+) transport ATPase YP_002414656.1 4114324 R 585056 CDS YP_002414657.1 218707138 7159191 complement(4115035..4115361) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8885264, 12071744, 8244952, 8455549, 9298646, 9868784; Product type pf : putative factor; acid-resistance protein 4115361 hdeB 7159191 hdeB Escherichia coli UMN026 acid-resistance protein YP_002414657.1 4115035 R 585056 CDS YP_002414658.1 218707139 7156645 complement(4115477..4115809) 1 NC_011751.1 inactive form; acid-resistance protein 4115809 hdeA 7156645 hdeA Escherichia coli UMN026 acid-resistance protein YP_002414658.1 4115477 R 585056 CDS YP_002414659.1 218707140 7156644 4116064..4116636 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8244952, 8455549; Product type pm : putative membrane component; acid-resistance membrane protein 4116636 hdeD 7156644 hdeD Escherichia coli UMN026 acid-resistance membrane protein YP_002414659.1 4116064 D 585056 CDS YP_002414660.1 218707141 7156646 4117433..4117960 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399493, 12940989, 14702398; Product type r : regulator; DNA-binding transcriptional activator 4117960 gadE 7156646 gadE Escherichia coli UMN026 DNA-binding transcriptional activator YP_002414660.1 4117433 D 585056 CDS YP_002414661.1 218707142 7156489 4118299..4119456 1 NC_011751.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4119456 mdtE 7156489 mdtE Escherichia coli UMN026 multidrug efflux system protein MdtE YP_002414661.1 4118299 D 585056 CDS YP_002414662.1 218707143 7157081 4119481..4122594 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug transporter, RpoS-dependent 4122594 mdtF 7157081 mdtF Escherichia coli UMN026 multidrug transporter, RpoS-dependent YP_002414662.1 4119481 D 585056 CDS YP_002414663.1 218707144 7157082 complement(4122957..4123685) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12446650; Product type r : regulator; DNA-binding transcriptional activator 4123685 gadW 7157082 gadW Escherichia coli UMN026 DNA-binding transcriptional activator YP_002414663.1 4122957 R 585056 CDS YP_002414664.1 218707145 7156492 complement(4124054..4124878) 1 NC_011751.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 4124878 gadX 7156492 gadX Escherichia coli UMN026 DNA-binding transcriptional regulator GadX YP_002414664.1 4124054 R 585056 CDS YP_002414665.1 218707146 7156491 complement(4125238..4126638) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme; glutamate decarboxylase A, PLP-dependent 4126638 gadA 7156491 gadA Escherichia coli UMN026 glutamate decarboxylase A, PLP-dependent YP_002414665.1 4125238 R 585056 CDS YP_002414666.1 218707147 7156486 complement(4126849..4128246) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8163487, 14563563; Product type e : enzyme; cytochrome C peroxidase 4128246 yhjA 7156486 yhjA Escherichia coli UMN026 cytochrome C peroxidase YP_002414666.1 4126849 R 585056 CDS YP_002414667.1 218707148 7159201 4128651..4130300 1 NC_011751.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4130300 treF 7159201 treF Escherichia coli UMN026 trehalase YP_002414667.1 4128651 D 585056 CDS YP_002414668.1 218707149 7158105 complement(4130351..4130953) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding response regulator in two-component regulatory system 4130953 yhjB 7158105 yhjB Escherichia coli UMN026 putative DNA-binding response regulator in two-component regulatory system YP_002414668.1 4130351 R 585056 CDS YP_002414669.1 218707150 7159202 4131401..4132372 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4132372 yhjC 7159202 yhjC Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414669.1 4131401 D 585056 CDS YP_002414670.1 218707151 7159203 4132421..4133434 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4133434 yhjD 7159203 yhjD Escherichia coli UMN026 hypothetical protein YP_002414670.1 4132421 D 585056 CDS YP_002414671.1 218707152 7159204 4133826..4135148 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4135148 yhjE 7159204 yhjE Escherichia coli UMN026 putative transporter YP_002414671.1 4133826 D 585056 CDS YP_002414672.1 218707153 7159205 complement(4135330..4137405) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane biogenesis protein 4137405 yhjG 7159205 yhjG Escherichia coli UMN026 putative outer membrane biogenesis protein YP_002414672.1 4135330 R 585056 CDS YP_002414673.1 218707154 7159206 complement(4137460..4138227) 1 NC_011751.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 4138227 yhjH 7159206 yhjH Escherichia coli UMN026 EAL domain-containing protein YP_002414673.1 4137460 R 585056 CDS YP_002414674.1 218707155 7159207 4138196..4138375 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4138375 7159207 ECUMN_4027 Escherichia coli UMN026 hypothetical protein YP_002414674.1 4138196 D 585056 CDS YP_002414675.1 218707156 7155413 4138459..4139388 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme; ketodeoxygluconokinase 4139388 kdgK 7155413 kdgK Escherichia coli UMN026 ketodeoxygluconokinase YP_002414675.1 4138459 D 585056 CDS YP_002414676.1 218707157 7156887 complement(4139360..4139944) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4139944 7156887 ECUMN_4029 Escherichia coli UMN026 hypothetical protein YP_002414676.1 4139360 R 585056 CDS YP_002414677.1 218707158 7155414 complement(4140006..4140326) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4140326 7155414 ECUMN_4030 Escherichia coli UMN026 hypothetical protein YP_002414677.1 4140006 R 585056 CDS YP_002414678.1 218707159 7155415 complement(4140330..4140809) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4140809 7155415 ECUMN_4031 Escherichia coli UMN026 hypothetical protein YP_002414678.1 4140330 R 585056 CDS YP_002414679.1 218707160 7155416 complement(4141163..4141612) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4141612 7155416 ECUMN_4033 Escherichia coli UMN026 hypothetical protein YP_002414679.1 4141163 R 585056 CDS YP_002414680.1 218707161 7155417 complement(4141792..4143288) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : putative enzyme; putative zinc-dependent peptidase 4143288 yhjJ 7155417 yhjJ Escherichia coli UMN026 putative zinc-dependent peptidase YP_002414680.1 4141792 R 585056 CDS YP_002414681.1 218707162 7159208 complement(4143508..4144794) 1 NC_011751.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4144794 dctA 7159208 dctA Escherichia coli UMN026 C4-dicarboxylate transporter DctA YP_002414681.1 4143508 R 585056 CDS YP_002414682.1 218707163 7156117 complement(4144977..4146926) 1 NC_011751.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase 4146926 yhjK 7156117 yhjK Escherichia coli UMN026 putative phosphodiesterase YP_002414682.1 4144977 R 585056 CDS YP_002414683.1 218707164 7155861 complement(4150502..4151608) 1 NC_011751.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 4151608 bcsZ 7155861 bcsZ Escherichia coli UMN026 endo-1,4-D-glucanase YP_002414683.1 4150502 R 585056 CDS YP_002414684.1 218707165 7155865 complement(4151615..4153954) 1 NC_011751.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 4153954 bcsB 7155865 bcsB Escherichia coli UMN026 cellulose synthase regulator protein YP_002414684.1 4151615 R 585056 CDS YP_002414685.1 218707166 7155858 complement(4156579..4157331) 1 NC_011751.1 cell division protein 4157331 7155858 ECUMN_4043 Escherichia coli UMN026 cell division protein YP_002414685.1 4156579 R 585056 CDS YP_002414686.1 218707167 7155418 complement(4157343..4157531) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4157531 yhjR 7155418 yhjR Escherichia coli UMN026 hypothetical protein YP_002414686.1 4157343 R 585056 CDS YP_002414687.1 218707168 7159210 4157803..4159374 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme; putative cellulose biosynthesis protease 4159374 bcsE 7159210 bcsE Escherichia coli UMN026 putative cellulose biosynthesis protease YP_002414687.1 4157803 D 585056 CDS YP_002414688.1 218707169 7155862 4159371..4159562 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4159562 bcsF 7155862 bcsF Escherichia coli UMN026 hypothetical protein YP_002414688.1 4159371 D 585056 CDS YP_002414689.1 218707170 7155863 4159559..4161238 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme; putative cellulose biosynthesis endoglucanase 4161238 bcsG 7155863 bcsG Escherichia coli UMN026 putative cellulose biosynthesis endoglucanase YP_002414689.1 4159559 D 585056 CDS YP_002414690.1 218707171 7157636 complement(4162080..4162241) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4162241 7157636 ECUMN_4048 Escherichia coli UMN026 hypothetical protein YP_002414690.1 4162080 R 585056 CDS YP_002414691.1 218707172 7155419 4162391..4163662 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter; transporter 4163662 yhjV 7155419 yhjV Escherichia coli UMN026 transporter YP_002414691.1 4162391 D 585056 CDS YP_002414692.1 218707173 7159211 complement(4163692..4164696) 1 NC_011751.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 4164696 dppF 7159211 dppF Escherichia coli UMN026 dipeptide transporter ATP-binding subunit YP_002414692.1 4163692 R 585056 CDS YP_002414693.1 218707174 7156199 complement(4164693..4165676) 1 NC_011751.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 4165676 dppD 7156199 dppD Escherichia coli UMN026 dipeptide transporter ATP-binding subunit YP_002414693.1 4164693 R 585056 CDS YP_002414694.1 218707175 7156198 complement(4165687..4166589) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter; dipeptide transporter 4166589 dppC 7156198 dppC Escherichia coli UMN026 dipeptide transporter YP_002414694.1 4165687 R 585056 CDS YP_002414695.1 218707176 7156197 complement(4166599..4167618) 1 NC_011751.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4167618 dppB 7156197 dppB Escherichia coli UMN026 dipeptide transporter permease DppB YP_002414695.1 4166599 R 585056 CDS YP_002414696.1 218707177 7156196 4167636..4167779 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4167779 7156196 ECUMN_4054 Escherichia coli UMN026 hypothetical protein YP_002414696.1 4167636 D 585056 CDS YP_002414697.1 218707178 7155420 complement(4167769..4169376) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter; dipeptide ABC transporter periplasmic-binding protein 4169376 dppA 7155420 dppA Escherichia coli UMN026 dipeptide ABC transporter periplasmic-binding protein YP_002414697.1 4167769 R 585056 CDS YP_002414698.1 218707179 7156195 complement(4170045..4170767) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 4170767 7156195 ECUMN_4056 Escherichia coli UMN026 transposase ORF B, IS3 family, IS150 group YP_002414698.1 4170045 R 585056 CDS YP_002414699.1 218707180 7155421 complement(4170872..4171402) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 4171402 7155421 ECUMN_4057 Escherichia coli UMN026 transposase ORF A, IS1397 YP_002414699.1 4170872 R 585056 CDS YP_002414700.1 218707181 7155616 complement(4171725..4173416) 1 NC_011751.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4173416 eptB 7155616 eptB Escherichia coli UMN026 phosphoethanolamine transferase YP_002414700.1 4171725 R 585056 CDS YP_002414701.1 218707182 7156266 complement(4173740..4174948) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4174948 yhjX 7156266 yhjX Escherichia coli UMN026 putative transporter YP_002414701.1 4173740 R 585056 CDS YP_002414702.1 218707183 7159212 complement(4175177..4175875) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4175875 yhjY 7159212 yhjY Escherichia coli UMN026 hypothetical protein YP_002414702.1 4175177 R 585056 CDS YP_002414703.1 218707184 7159213 4176033..4176596 1 NC_011751.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4176596 tag 7159213 tag Escherichia coli UMN026 3-methyl-adenine DNA glycosylase I YP_002414703.1 4176033 D 585056 CDS YP_002414704.1 218707185 7158018 4176593..4177033 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11237876; Product type pe : putative enzyme; hypothetical protein 4177033 yiaC 7158018 yiaC Escherichia coli UMN026 hypothetical protein YP_002414704.1 4176593 D 585056 CDS YP_002414705.1 218707186 7159216 complement(4177002..4179281) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme; biotin sulfoxide reductase 4179281 bisC 7159216 bisC Escherichia coli UMN026 biotin sulfoxide reductase YP_002414705.1 4177002 R 585056 CDS YP_002414706.1 218707187 7155884 4179488..4180147 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative outer membrane lipoprotein 4180147 yiaD 7155884 yiaD Escherichia coli UMN026 putative outer membrane lipoprotein YP_002414706.1 4179488 D 585056 CDS YP_002414707.1 218707188 7159217 4180251..4181225 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme; 2-oxo-carboxylic acid reductase 4181225 tiaE 7159217 tiaE Escherichia coli UMN026 2-oxo-carboxylic acid reductase YP_002414707.1 4180251 D 585056 CDS YP_002414708.1 218707189 7158070 complement(4181275..4181985) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4181985 yiaF 7158070 yiaF Escherichia coli UMN026 hypothetical protein YP_002414708.1 4181275 R 585056 CDS YP_002414709.1 218707190 7159218 4182419..4182709 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4182709 yiaG 7159218 yiaG Escherichia coli UMN026 putative transcriptional regulator YP_002414709.1 4182419 D 585056 CDS YP_002414710.1 218707191 7159219 4182990..4183202 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor; major cold shock protein 4183202 cspA 7159219 cspA Escherichia coli UMN026 major cold shock protein YP_002414710.1 4182990 D 585056 CDS YP_002414711.1 218707192 7156034 complement(4183864..4185933) 1 NC_011751.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4185933 glyS 7156034 glyS Escherichia coli UMN026 glycyl-tRNA synthetase subunit beta YP_002414711.1 4183864 R 585056 CDS YP_002414712.1 218707193 7156587 complement(4185943..4186854) 1 NC_011751.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4186854 glyQ 7156587 glyQ Escherichia coli UMN026 glycyl-tRNA synthetase subunit alpha YP_002414712.1 4185943 R 585056 CDS YP_002414713.1 218707194 7156586 complement(4186949..4187257) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4187257 ysaB 7156586 ysaB Escherichia coli UMN026 hypothetical protein YP_002414713.1 4186949 R 585056 CDS YP_002414714.1 218707195 7159664 4187432..4188427 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4188427 yiaH 7159664 yiaH Escherichia coli UMN026 hypothetical protein YP_002414714.1 4187432 D 585056 CDS YP_002414715.1 218707196 7159220 complement(4188469..4188906) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4188906 yiaA 7159220 yiaA Escherichia coli UMN026 hypothetical protein YP_002414715.1 4188469 R 585056 CDS YP_002414716.1 218707197 7159214 complement(4188951..4189292) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6320721; Product type pm : putative membrane component; hypothetical protein 4189292 yiaB 7159214 yiaB Escherichia coli UMN026 hypothetical protein YP_002414716.1 4188951 R 585056 CDS YP_002414717.1 218707198 7159215 complement(4189461..4190915) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme; xylulokinase 4190915 xylB 7159215 xylB Escherichia coli UMN026 xylulokinase YP_002414717.1 4189461 R 585056 CDS YP_002414718.1 218707199 7158253 complement(4190987..4192309) 1 NC_011751.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4192309 xylA 7158253 xylA Escherichia coli UMN026 xylose isomerase YP_002414718.1 4190987 R 585056 CDS YP_002414719.1 218707200 7158252 4192675..4193667 1 NC_011751.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4193667 xylF 7158252 xylF Escherichia coli UMN026 D-xylose transporter subunit XylF YP_002414719.1 4192675 D 585056 CDS YP_002414720.1 218707201 7158254 4193745..4195286 1 NC_011751.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4195286 xylG 7158254 xylG Escherichia coli UMN026 xylose transporter ATP-binding subunit YP_002414720.1 4193745 D 585056 CDS YP_002414721.1 218707202 7158255 4195264..4196445 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500; Product type t : transporter; D-xylose ABC transporter membrane protein 4196445 xylH 7158255 xylH Escherichia coli UMN026 D-xylose ABC transporter membrane protein YP_002414721.1 4195264 D 585056 CDS YP_002414722.1 218707203 7158256 4196357..4196533 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4196533 7158256 ECUMN_4080 Escherichia coli UMN026 hypothetical protein YP_002414722.1 4196357 D 585056 CDS YP_002414723.1 218707204 7155423 4196523..4197701 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator; DNA-binding transcriptional activator, xylose-binding 4197701 xylR 7155423 xylR Escherichia coli UMN026 DNA-binding transcriptional activator, xylose-binding YP_002414723.1 4196523 D 585056 CDS YP_002414724.1 218707205 7158257 complement(4197809..4198633) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897; hypothetical protein 4198633 bax 7158257 bax Escherichia coli UMN026 hypothetical protein YP_002414724.1 4197809 R 585056 CDS YP_002414725.1 218707206 7155854 4198953..4200983 1 NC_011751.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4200983 malS 7155854 malS Escherichia coli UMN026 periplasmic alpha-amylase YP_002414725.1 4198953 D 585056 CDS YP_002414726.1 218707207 7157049 4201161..4202414 1 NC_011751.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4202414 avtA 7157049 avtA Escherichia coli UMN026 valine--pyruvate transaminase YP_002414726.1 4201161 D 585056 CDS YP_002414727.1 218707208 7155844 complement(4202453..4202926) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative hydrogenase, 4Fe-4S ferredoxin-type component 4202926 yiaI 7155844 yiaI Escherichia coli UMN026 putative hydrogenase, 4Fe-4S ferredoxin-type component YP_002414727.1 4202453 R 585056 CDS YP_002414728.1 218707209 7159221 complement(4203028..4203876) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator; DNA-binding transcriptional repressor 4203876 yiaJ 7159221 yiaJ Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002414728.1 4203028 R 585056 CDS YP_002414729.1 218707210 7159222 4204078..4205076 1 NC_011751.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4205076 yiaK 7159222 yiaK Escherichia coli UMN026 2,3-diketo-L-gulonate reductase YP_002414729.1 4204078 D 585056 CDS YP_002414730.1 218707211 7159223 4205087..4205554 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392; hypothetical protein 4205554 yiaL 7159223 yiaL Escherichia coli UMN026 hypothetical protein YP_002414730.1 4205087 D 585056 CDS YP_002414731.1 218707212 7159224 4205672..4206145 1 NC_011751.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM 4206145 yiaM 7159224 yiaM Escherichia coli UMN026 2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM YP_002414731.1 4205672 D 585056 CDS YP_002414732.1 218707213 7159225 4206148..4207425 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 4207425 yiaN 7159225 yiaN Escherichia coli UMN026 transporter YP_002414732.1 4206148 D 585056 CDS YP_002414733.1 218707214 7159226 4207438..4208424 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 4208424 yiaO 7159226 yiaO Escherichia coli UMN026 transporter YP_002414733.1 4207438 D 585056 CDS YP_002414734.1 218707215 7159227 4208428..4209924 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme; L-xylulose kinase 4209924 lyxK 7159227 lyxK Escherichia coli UMN026 L-xylulose kinase YP_002414734.1 4208428 D 585056 CDS YP_002414735.1 218707216 7157035 4209921..4210583 1 NC_011751.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4210583 sgbH 7157035 sgbH Escherichia coli UMN026 3-keto-L-gulonate-6-phosphate decarboxylase YP_002414735.1 4209921 D 585056 CDS YP_002414736.1 218707217 7157912 4210576..4211436 1 NC_011751.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 4211436 sgbU 7157912 sgbU Escherichia coli UMN026 putative L-xylulose 5-phosphate 3-epimerase YP_002414736.1 4210576 D 585056 CDS YP_002414737.1 218707218 7157913 4211430..4212125 1 NC_011751.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4212125 sgbE 7157913 sgbE Escherichia coli UMN026 L-ribulose-5-phosphate 4-epimerase YP_002414737.1 4211430 D 585056 CDS YP_002414738.1 218707219 7157911 complement(4212157..4212972) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator protein 4212972 7157911 ECUMN_4097 Escherichia coli UMN026 putative transcriptional regulator protein YP_002414738.1 4212157 R 585056 CDS YP_002414739.1 218707220 7155424 4213198..4214598 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative major facilitator superfamily permease 4214598 7155424 ECUMN_4098 Escherichia coli UMN026 putative major facilitator superfamily permease YP_002414739.1 4213198 D 585056 CDS YP_002414740.1 218707221 7155425 4214609..4216573 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4216573 7155425 ECUMN_4099 Escherichia coli UMN026 hypothetical protein YP_002414740.1 4214609 D 585056 CDS YP_002414741.1 218707222 7155426 complement(4216645..4217055) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4217055 7155426 ECUMN_4100 Escherichia coli UMN026 hypothetical protein YP_002414741.1 4216645 R 585056 CDS YP_002414742.1 218707223 7155427 complement(4217072..4217257) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4217257 7155427 ECUMN_4101 Escherichia coli UMN026 hypothetical protein YP_002414742.1 4217072 R 585056 CDS YP_002414743.1 218707224 7155428 4217232..4217405 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4217405 7155428 ECUMN_4102 Escherichia coli UMN026 hypothetical protein YP_002414743.1 4217232 D 585056 CDS YP_002414744.1 218707225 7155429 complement(4217535..4219073) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme; aldehyde dehydrogenase B 4219073 aldB 7155429 aldB Escherichia coli UMN026 aldehyde dehydrogenase B YP_002414744.1 4217535 R 585056 CDS YP_002414745.1 218707226 7155723 complement(4219274..4220425) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme; putative alcohol dehydrogenase 4220425 yiaY 7155723 yiaY Escherichia coli UMN026 putative alcohol dehydrogenase YP_002414745.1 4219274 R 585056 CDS YP_002414746.1 218707227 7159228 complement(4220615..4222459) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor; selenocysteinyl-tRNA -specific translation factor 4222459 selB 7159228 selB Escherichia coli UMN026 selenocysteinyl-tRNA -specific translation factor YP_002414746.1 4220615 R 585056 CDS YP_002414747.1 218707228 7157894 complement(4222456..4223847) 1 NC_011751.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4223847 selA 7157894 selA Escherichia coli UMN026 selenocysteine synthase YP_002414747.1 4222456 R 585056 CDS YP_002414748.1 218707229 7157893 complement(4223945..4224553) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8387990; Product type pe : putative enzyme; putative glutathione S-transferase 4224553 yibF 7157893 yibF Escherichia coli UMN026 putative glutathione S-transferase YP_002414748.1 4223945 R 585056 CDS YP_002414749.1 218707230 7159230 complement(4224624..4225760) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4225760 yibH 7159230 yibH Escherichia coli UMN026 hypothetical protein YP_002414749.1 4224624 R 585056 CDS YP_002414750.1 218707231 7159231 complement(4225763..4226125) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4226125 yibI 7159231 yibI Escherichia coli UMN026 hypothetical protein YP_002414750.1 4225763 R 585056 CDS YP_002414751.1 218707232 7159232 4226662..4228575 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter; PTS system mannitol-specific transporter subunit IIABC 4228575 mtlA 7159232 mtlA Escherichia coli UMN026 PTS system mannitol-specific transporter subunit IIABC YP_002414751.1 4226662 D 585056 CDS YP_002414752.1 218707233 7157191 4228804..4229952 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme; mannitol-1-phosphate 5-dehydrogenase 4229952 mtlD 7157191 mtlD Escherichia coli UMN026 mannitol-1-phosphate 5-dehydrogenase YP_002414752.1 4228804 D 585056 CDS YP_002414753.1 218707234 7157192 4229952..4230539 1 NC_011751.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4230539 mtlR 7157192 mtlR Escherichia coli UMN026 mannitol repressor protein YP_002414753.1 4229952 D 585056 CDS YP_002414754.1 218707235 7157193 complement(4230551..4230760) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4230760 yibT 7157193 yibT Escherichia coli UMN026 hypothetical protein YP_002414754.1 4230551 R 585056 CDS YP_002414755.1 218707236 7159237 4231044..4231406 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4231406 yibL 7159237 yibL Escherichia coli UMN026 hypothetical protein YP_002414755.1 4231044 D 585056 CDS YP_002414756.1 218707237 7159234 4231967..4232650 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4232650 7159234 ECUMN_4115 Escherichia coli UMN026 hypothetical protein YP_002414756.1 4231967 D 585056 CDS YP_002414757.1 218707238 7155432 4238337..4239992 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter; L-lactate permease 4239992 lldP 7155432 lldP Escherichia coli UMN026 L-lactate permease YP_002414757.1 4238337 D 585056 CDS YP_002414758.1 218707239 7156991 4239992..4240768 1 NC_011751.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4240768 lldR 7156991 lldR Escherichia coli UMN026 DNA-binding transcriptional repressor LldR YP_002414758.1 4239992 D 585056 CDS YP_002414759.1 218707240 7156992 4240765..4241955 1 NC_011751.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4241955 lldD 7156992 lldD Escherichia coli UMN026 L-lactate dehydrogenase YP_002414759.1 4240765 D 585056 CDS YP_002414760.1 218707241 7156990 4242028..4242501 1 NC_011751.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA /rRNA methyltransferase YibK 4242501 yibK 7156990 yibK Escherichia coli UMN026 putative tRNA /rRNA methyltransferase YibK YP_002414760.1 4242028 D 585056 CDS YP_002414761.1 218707242 7159233 complement(4242558..4243280) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family, IS150 group 4243280 7159233 ECUMN_4122 Escherichia coli UMN026 transposase ORF B, IS3 family, IS150 group YP_002414761.1 4242558 R 585056 CDS YP_002414762.1 218707243 7155433 complement(4243385..4243915) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS1397 4243915 7155433 ECUMN_4123 Escherichia coli UMN026 transposase ORF A, IS1397 YP_002414762.1 4243385 R 585056 CDS YP_002414763.1 218707244 7155434 complement(4243989..4244810) 1 NC_011751.1 catalyzes the O-acetylation of serine; serine acetyltransferase 4244810 cysE 7155434 cysE Escherichia coli UMN026 serine acetyltransferase YP_002414763.1 4243989 R 585056 CDS YP_002414764.1 218707245 7156082 complement(4244890..4245909) 1 NC_011751.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 4245909 gpsA 7156082 gpsA Escherichia coli UMN026 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002414764.1 4244890 R 585056 CDS YP_002414765.1 218707246 7156607 complement(4245909..4246376) 1 NC_011751.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 4246376 secB 7156607 secB Escherichia coli UMN026 preprotein translocase subunit SecB YP_002414765.1 4245909 R 585056 CDS YP_002414766.1 218707247 7157886 complement(4246439..4246690) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier; glutaredoxin 3 4246690 grxC 7157886 grxC Escherichia coli UMN026 glutaredoxin 3 YP_002414766.1 4246439 R 585056 CDS YP_002414767.1 218707248 7156616 complement(4246833..4247264) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative rhodanese-related sulfurtransferase 4247264 yibN 7156616 yibN Escherichia coli UMN026 putative rhodanese-related sulfurtransferase YP_002414767.1 4246833 R 585056 CDS YP_002414768.1 218707249 7159235 4247509..4249053 1 NC_011751.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4249053 gpmI 7159235 gpmI Escherichia coli UMN026 phosphoglyceromutase YP_002414768.1 4247509 D 585056 CDS YP_002414769.1 218707250 7156605 4249087..4250346 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process; hypothetical protein 4250346 envC 7156605 envC Escherichia coli UMN026 hypothetical protein YP_002414769.1 4249087 D 585056 CDS YP_002414770.1 218707251 7156254 4250350..4251309 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative polysaccharide deacetylase 4251309 yibQ 7156254 yibQ Escherichia coli UMN026 putative polysaccharide deacetylase YP_002414770.1 4250350 D 585056 CDS YP_002414771.1 218707252 7159236 complement(4251296..4252330) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : putative enzyme; putative glycosyl transferase 4252330 yibD 7159236 yibD Escherichia coli UMN026 putative glycosyl transferase YP_002414771.1 4251296 R 585056 CDS YP_002414772.1 218707253 7159229 complement(4252569..4253594) 1 NC_011751.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4253594 tdh 7159229 tdh Escherichia coli UMN026 L-threonine 3-dehydrogenase YP_002414772.1 4252569 R 585056 CDS YP_002414773.1 218707254 7158043 complement(4253604..4254800) 1 NC_011751.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 4254800 kbl 7158043 kbl Escherichia coli UMN026 2-amino-3-ketobutyrate coenzyme A ligase YP_002414773.1 4253604 R 585056 CDS YP_002414774.1 218707255 7156885 complement(4255076..4255933) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4255933 htrL 7156885 htrL Escherichia coli UMN026 hypothetical protein YP_002414774.1 4255076 R 585056 CDS YP_002414775.1 218707256 7156731 4256237..4257169 1 NC_011751.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase 4257169 rfaD 7156731 rfaD Escherichia coli UMN026 ADP-L-glycero-D-mannoheptose-6-epimerase YP_002414775.1 4256237 D 585056 CDS YP_002414776.1 218707257 7158216 4257179..4258225 1 NC_011751.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4258225 waaF 7158216 waaF Escherichia coli UMN026 ADP-heptose:LPS heptosyltransferase II YP_002414776.1 4257179 D 585056 CDS YP_002414777.1 218707258 7158217 4258229..4259221 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme; ADP-heptose:LPS heptosyl transferase I 4259221 waaC 7158217 waaC Escherichia coli UMN026 ADP-heptose:LPS heptosyl transferase I YP_002414777.1 4258229 D 585056 CDS YP_002414778.1 218707259 7158215 4259218..4260426 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; O-antigen ligase 4260426 rfaL 7158215 rfaL Escherichia coli UMN026 O-antigen ligase YP_002414778.1 4259218 D 585056 CDS YP_002414779.1 218707260 7157658 complement(4260464..4261606) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase 4261606 rfaK 7157658 rfaK Escherichia coli UMN026 Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase YP_002414779.1 4260464 R 585056 CDS YP_002414780.1 218707261 7157657 complement(4261615..4262628) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 99251135, 1624461; Product type e : enzyme; Lipopolysaccharide 1,2-glucosyltransferase 4262628 rfaJ 7157657 rfaJ Escherichia coli UMN026 Lipopolysaccharide 1,2-glucosyltransferase YP_002414780.1 4261615 R 585056 CDS YP_002414781.1 218707262 7157656 complement(4262653..4263360) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1624462, 8041620, 9278503, 92250420, 92325067, 9756860; Product type e : enzyme; lipopolysaccharide core biosynthesis protein 4263360 rfaY 7157656 rfaY Escherichia coli UMN026 lipopolysaccharide core biosynthesis protein YP_002414781.1 4262653 R 585056 CDS YP_002414782.1 218707263 7157659 complement(4263386..4264393) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 9765561, 1624461; Product type e : enzyme; Lipopolysaccharide 1,3-galactosyltransferase 4264393 rfaI 7157659 rfaI Escherichia coli UMN026 Lipopolysaccharide 1,3-galactosyltransferase YP_002414782.1 4263386 R 585056 CDS YP_002414783.1 218707264 7157655 complement(4264436..4265242) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme; kinase that phosphorylates core heptose of lipopolysaccharide 4265242 waaP 7157655 waaP Escherichia coli UMN026 kinase that phosphorylates core heptose of lipopolysaccharide YP_002414783.1 4264436 R 585056 CDS YP_002414784.1 218707265 7158219 complement(4265226..4266350) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme; glucosyltransferase I 4266350 waaG 7158219 waaG Escherichia coli UMN026 glucosyltransferase I YP_002414784.1 4265226 R 585056 CDS YP_002414785.1 218707266 7158218 complement(4266347..4267405) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9756860, 1447141, 1732225; Product type e : enzyme; lipopolysaccharide core biosynthesis protein 4267405 waaQ 7158218 waaQ Escherichia coli UMN026 lipopolysaccharide core biosynthesis protein YP_002414785.1 4266347 R 585056 CDS YP_002414786.1 218707267 7158220 4267818..4269095 1 NC_011751.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4269095 kdtA 7158220 kdtA Escherichia coli UMN026 3-deoxy-D-manno-octulosonic-acid transferase YP_002414786.1 4267818 D 585056 CDS YP_002414787.1 218707268 7156899 4269103..4269582 1 NC_011751.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4269582 coaD 7156899 coaD Escherichia coli UMN026 phosphopantetheine adenylyltransferase YP_002414787.1 4269103 D 585056 CDS YP_002414788.1 218707269 7155989 complement(4269621..4270430) 1 NC_011751.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4270430 mutM 7155989 mutM Escherichia coli UMN026 formamidopyrimidine-DNA glycosylase YP_002414788.1 4269621 R 585056 CDS YP_002414789.1 218707270 7157213 complement(4270528..4270695) 1 NC_011751.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4270695 rpmG 7157213 rpmG Escherichia coli UMN026 50S ribosomal protein L33 YP_002414789.1 4270528 R 585056 CDS YP_002414790.1 218707271 7157754 complement(4270716..4270952) 1 NC_011751.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4270952 rpmB 7157754 rpmB Escherichia coli UMN026 50S ribosomal protein L28 YP_002414790.1 4270716 R 585056 CDS YP_002414791.1 218707272 7157749 complement(4271169..4271837) 1 NC_011751.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4271837 radC 7157749 radC Escherichia coli UMN026 DNA repair protein RadC YP_002414791.1 4271169 R 585056 CDS YP_002414792.1 218707273 7159249 4272009..4273229 1 NC_011751.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4273229 dfp 7159249 dfp Escherichia coli UMN026 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002414792.1 4272009 D 585056 CDS YP_002414793.1 218707274 7156147 4273210..4273665 1 NC_011751.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4273665 dut 7156147 dut Escherichia coli UMN026 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002414793.1 4273210 D 585056 CDS YP_002414794.1 218707275 7156214 4273772..4274368 1 NC_011751.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4274368 slmA 7156214 slmA Escherichia coli UMN026 nucleoid occlusion protein YP_002414794.1 4273772 D 585056 CDS YP_002414795.1 218707276 7158138 complement(4274405..4275046) 1 NC_011751.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4275046 pyrE 7158138 pyrE Escherichia coli UMN026 orotate phosphoribosyltransferase YP_002414795.1 4274405 R 585056 CDS YP_002414796.1 218707277 7157600 complement(4275112..4275852) 1 NC_011751.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4275852 rph 7157600 rph Escherichia coli UMN026 ribonuclease PH YP_002414796.1 4275112 R 585056 CDS YP_002414797.1 218707278 7157723 4275955..4276818 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4276818 yicC 7157723 yicC Escherichia coli UMN026 hypothetical protein YP_002414797.1 4275955 D 585056 CDS YP_002414798.1 218707279 7159238 4277040..4277864 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 913680, 94334998, 95095962, 1925027, 2158980, 2664418, 8002613, 8057377, 8195095; Product type cp : cell process; DNA-damage-inducible protein D 4277864 dinD 7159238 dinD Escherichia coli UMN026 DNA-damage-inducible protein D YP_002414798.1 4277040 D 585056 CDS YP_002414799.1 218707280 7156167 4278155..4278772 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4278772 yicG 7156167 yicG Escherichia coli UMN026 hypothetical protein YP_002414799.1 4278155 D 585056 CDS YP_002414800.1 218707281 7159240 complement(4278769..4280451) 1 NC_011751.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 4280451 ligB 7159240 ligB Escherichia coli UMN026 NAD-dependent DNA ligase LigB YP_002414800.1 4278769 R 585056 CDS YP_002414801.1 218707282 7156980 4280709..4281332 1 NC_011751.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4281332 gmk 7156980 gmk Escherichia coli UMN026 guanylate kinase YP_002414801.1 4280709 D 585056 CDS YP_002414802.1 218707283 7156590 4281387..4281662 1 NC_011751.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4281662 rpoZ 7156590 rpoZ Escherichia coli UMN026 DNA-directed RNA polymerase subunit omega YP_002414802.1 4281387 D 585056 CDS YP_002414803.1 218707284 7157765 4281681..4283789 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4283789 spoT 7157765 spoT Escherichia coli UMN026 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002414803.1 4281681 D 585056 CDS YP_002414804.1 218707285 7157964 4283796..4284485 1 NC_011751.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4284485 trmH 7157964 trmH Escherichia coli UMN026 tRNA guanosine-2'-O-methyltransferase YP_002414804.1 4283796 D 585056 CDS YP_002414805.1 218707286 7158115 4284491..4286572 1 NC_011751.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4286572 recG 7158115 recG Escherichia coli UMN026 ATP-dependent DNA helicase RecG YP_002414805.1 4284491 D 585056 CDS YP_002414806.1 218707287 7157642 complement(4286606..4287811) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter; glutamate transporter 4287811 gltS 7157642 gltS Escherichia coli UMN026 glutamate transporter YP_002414806.1 4286606 R 585056 CDS YP_002414807.1 218707288 7156581 4288090..4289481 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4289481 yicE 7156581 yicE Escherichia coli UMN026 putative transporter YP_002414807.1 4288090 D 585056 CDS YP_002414808.1 218707289 7159239 4289602..4291311 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4291311 yicH 7159239 yicH Escherichia coli UMN026 hypothetical protein YP_002414808.1 4289602 D 585056 CDS YP_002414809.1 218707290 7159242 4292627..4293955 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element 4293955 insG 7159242 insG Escherichia coli UMN026 putative IS4 transposase; KpLE2 phage-like element YP_002414809.1 4292627 D 585056 CDS YP_002414810.1 218707291 7159243 complement(4295130..4296512) 1 NC_011751.1 may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter 4296512 yicJ 7159243 yicJ Escherichia coli UMN026 putative transporter YP_002414810.1 4295130 R 585056 CDS YP_002414811.1 218707292 7155590 4297537..4298721 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10438463, 10209755; Product type pt : putative transporter; putative sugar efflux system 4298721 setC 7155590 setC Escherichia coli UMN026 putative sugar efflux system YP_002414811.1 4297537 D 585056 CDS YP_002414812.1 218707293 7157902 4298832..4299755 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4299755 yicL 7157902 yicL Escherichia coli UMN026 hypothetical protein YP_002414812.1 4298832 D 585056 CDS YP_002414813.1 218707294 7159245 complement(4299759..4300577) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88298691, 89359178, 9914480, 3003106; Product type lp : lipoprotein; cytoplasmic membrane lipoprotein-28 4300577 nlpA 7159245 nlpA Escherichia coli UMN026 cytoplasmic membrane lipoprotein-28 YP_002414813.1 4299759 R 585056 CDS YP_002414814.1 218707295 7157285 4300718..4301080 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4301080 yicS 7157285 yicS Escherichia coli UMN026 hypothetical protein YP_002414814.1 4300718 D 585056 CDS YP_002414815.1 218707296 7159250 4301382..4301879 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative type III secretion chaperone 4301879 7159250 ECUMN_4181 Escherichia coli UMN026 putative type III secretion chaperone YP_002414815.1 4301382 D 585056 CDS YP_002414816.1 218707297 7155435 4302126..4303907 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4303907 7155435 ECUMN_4182 Escherichia coli UMN026 hypothetical protein YP_002414816.1 4302126 D 585056 CDS YP_002414817.1 218707298 7155436 4303920..4305071 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4305071 7155436 ECUMN_4183 Escherichia coli UMN026 hypothetical protein YP_002414817.1 4303920 D 585056 CDS YP_002414818.1 218707299 7155437 4305115..4306464 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4306464 7155437 ECUMN_4184 Escherichia coli UMN026 hypothetical protein YP_002414818.1 4305115 D 585056 CDS YP_002414819.1 218707300 7155438 4306667..4308364 1 NC_011751.1 Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system; invasion protein regulator 4308364 7155438 ECUMN_4185 Escherichia coli UMN026 invasion protein regulator YP_002414819.1 4306667 D 585056 CDS YP_002414820.1 218707301 7155439 complement(4308416..4318672) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4318672 7155439 ECUMN_4186 Escherichia coli UMN026 hypothetical protein YP_002414820.1 4308416 R 585056 CDS YP_002414821.1 218707302 7155440 complement(4318874..4320232) 1 NC_011751.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter 4320232 nepI 7155440 nepI Escherichia coli UMN026 ribonucleoside transporter YP_002414821.1 4318874 R 585056 CDS YP_002414822.1 218707303 7159246 4320285..4320644 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4320644 7159246 ECUMN_4188 Escherichia coli UMN026 hypothetical protein YP_002414822.1 4320285 D 585056 CDS YP_002414823.1 218707304 7155441 4320628..4320951 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptional regulator 4320951 7155441 ECUMN_4189 Escherichia coli UMN026 putative transcriptional regulator YP_002414823.1 4320628 D 585056 CDS YP_002414824.1 218707305 7155442 complement(4321067..4321519) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4321519 yicN 7155442 yicN Escherichia coli UMN026 hypothetical protein YP_002414824.1 4321067 R 585056 CDS YP_002414825.1 218707306 7159247 complement(4321572..4322906) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative xanthine/uracil permease 4322906 yicO 7159247 yicO Escherichia coli UMN026 putative xanthine/uracil permease YP_002414825.1 4321572 R 585056 CDS YP_002414826.1 218707307 7159248 4323081..4324847 1 NC_011751.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4324847 ade 7159248 ade Escherichia coli UMN026 cryptic adenine deaminase YP_002414826.1 4323081 D 585056 CDS YP_002414827.1 218707308 7155697 complement(4324959..4325468) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transposase IS605 family, IS200 group 4325468 7155697 ECUMN_4193 Escherichia coli UMN026 transposase IS605 family, IS200 group YP_002414827.1 4324959 R 585056 CDS YP_002414828.1 218707309 7155443 complement(4325374..4325595) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4325595 7155443 ECUMN_4194 Escherichia coli UMN026 hypothetical protein YP_002414828.1 4325374 R 585056 CDS YP_002414829.1 218707310 7155444 complement(4325605..4326996) 1 NC_011751.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4326996 uhpT 7155444 uhpT Escherichia coli UMN026 sugar phosphate antiporter YP_002414829.1 4325605 R 585056 CDS YP_002414830.1 218707311 7158173 complement(4327134..4328453) 1 NC_011751.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4328453 uhpC 7158173 uhpC Escherichia coli UMN026 regulatory protein UhpC YP_002414830.1 4327134 R 585056 CDS YP_002414831.1 218707312 7158172 complement(4328463..4329965) 1 NC_011751.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4329965 uhpB 7158172 uhpB Escherichia coli UMN026 sensory histidine kinase UhpB YP_002414831.1 4328463 R 585056 CDS YP_002414832.1 218707313 7158171 complement(4329965..4330555) 1 NC_011751.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4330555 uhpA 7158171 uhpA Escherichia coli UMN026 DNA-binding transcriptional activator UhpA YP_002414832.1 4329965 R 585056 CDS YP_002414833.1 218707314 7158170 complement(4330717..4332207) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4332207 7158170 ECUMN_4199 Escherichia coli UMN026 hypothetical protein YP_002414833.1 4330717 R 585056 CDS YP_002414834.1 218707315 7155445 complement(4332462..4333769) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4333769 7155445 ECUMN_4200 Escherichia coli UMN026 hypothetical protein YP_002414834.1 4332462 R 585056 CDS YP_002414835.1 218707316 7155446 complement(4334022..4334312) 1 NC_011751.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4334312 ilvN 7155446 ilvN Escherichia coli UMN026 acetolactate synthase 1 regulatory subunit YP_002414835.1 4334022 R 585056 CDS YP_002414836.1 218707317 7156807 complement(4334316..4336004) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme; acetolactate synthase catalytic subunit 4336004 ilvB 7156807 ilvB Escherichia coli UMN026 acetolactate synthase catalytic subunit YP_002414836.1 4334316 R 585056 CDS YP_002414837.1 218707318 7156798 complement(4336110..4336208) 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvB operon leader peptide 4336208 ivbL 7156798 ivbL Escherichia coli UMN026 ilvB operon leader peptide YP_002414837.1 4336110 R 585056 CDS YP_002414838.1 218707319 7156873 4336482..4336640 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4336640 7156873 ECUMN_4204 Escherichia coli UMN026 hypothetical protein YP_002414838.1 4336482 D 585056 CDS YP_002414839.1 218707320 7155447 4337142..4338326 1 NC_011751.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4338326 emrD 7155447 emrD Escherichia coli UMN026 multidrug resistance protein D YP_002414839.1 4337142 D 585056 CDS YP_002414840.1 218707321 7156242 complement(4338334..4338831) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4338831 yidF 7156242 yidF Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414840.1 4338334 R 585056 CDS YP_002414841.1 218707322 7159256 complement(4338828..4339190) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4339190 yidG 7159256 yidG Escherichia coli UMN026 hypothetical protein YP_002414841.1 4338828 R 585056 CDS YP_002414842.1 218707323 7159257 complement(4339180..4339527) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4339527 yidH 7159257 yidH Escherichia coli UMN026 hypothetical protein YP_002414842.1 4339180 R 585056 CDS YP_002414843.1 218707324 7159258 4339635..4340084 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4340084 yidI 7159258 yidI Escherichia coli UMN026 hypothetical protein YP_002414843.1 4339635 D 585056 CDS YP_002414844.1 218707325 7159259 complement(4340131..4341624) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sulfatase/phosphatase 4341624 yidJ 7159259 yidJ Escherichia coli UMN026 putative sulfatase/phosphatase YP_002414844.1 4340131 R 585056 CDS YP_002414845.1 218707326 7159260 complement(4341621..4343336) 1 NC_011751.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK 4343336 yidK 7159260 yidK Escherichia coli UMN026 putative symporter YidK YP_002414845.1 4341621 R 585056 CDS YP_002414846.1 218707327 7159261 4343473..4344396 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4344396 yidL 7159261 yidL Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414846.1 4343473 D 585056 CDS YP_002414847.1 218707328 7159262 complement(4344393..4345715) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 6-phospho-glucosidase 4345715 7159262 ECUMN_4213 Escherichia coli UMN026 6-phospho-glucosidase YP_002414847.1 4344393 R 585056 CDS YP_002414848.1 218707329 7155448 complement(4345715..4347592) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative PTS system alpha-glucoside-specific EIICB component 4347592 7155448 ECUMN_4214 Escherichia coli UMN026 putative PTS system alpha-glucoside-specific EIICB component YP_002414848.1 4345715 R 585056 CDS YP_002414849.1 218707330 7155449 4347627..4348343 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4348343 yidP 7155449 yidP Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414849.1 4347627 D 585056 CDS YP_002414850.1 218707331 7159263 complement(4348340..4350001) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : putative transporter; hypothetical protein 4350001 yidE 7159263 yidE Escherichia coli UMN026 hypothetical protein YP_002414850.1 4348340 R 585056 CDS YP_002414851.1 218707332 7159255 complement(4350197..4350625) 1 NC_011751.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4350625 ibpB 7159255 ibpB Escherichia coli UMN026 heat shock chaperone IbpB YP_002414851.1 4350197 R 585056 CDS YP_002414852.1 218707333 7156781 complement(4350737..4351150) 1 NC_011751.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4351150 ibpA 7156781 ibpA Escherichia coli UMN026 heat shock protein IbpA YP_002414852.1 4350737 R 585056 CDS YP_002414853.1 218707334 7156780 4351456..4351788 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4351788 yidQ 7156780 yidQ Escherichia coli UMN026 hypothetical protein YP_002414853.1 4351456 D 585056 CDS YP_002414854.1 218707335 7159264 complement(4351790..4353004) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4353004 yidR 7159264 yidR Escherichia coli UMN026 hypothetical protein YP_002414854.1 4351790 R 585056 CDS YP_002414855.1 218707336 7159265 4353084..4354205 1 NC_011751.1 FAD/NAD(P)-binding domain; putative oxidoreductase 4354205 cbrA 7159265 cbrA Escherichia coli UMN026 putative oxidoreductase YP_002414855.1 4353084 D 585056 CDS YP_002414856.1 218707337 7155924 complement(4354166..4355458) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter; D-galactonate transporter 4355458 dgoT 7155924 dgoT Escherichia coli UMN026 D-galactonate transporter YP_002414856.1 4354166 R 585056 CDS YP_002414857.1 218707338 7156153 complement(4355578..4356726) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; galactonate dehydratase 4356726 dgoD 7156153 dgoD Escherichia coli UMN026 galactonate dehydratase YP_002414857.1 4355578 R 585056 CDS YP_002414858.1 218707339 7156150 complement(4356723..4357340) 1 NC_011751.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4357340 dgoA 7156150 dgoA Escherichia coli UMN026 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002414858.1 4356723 R 585056 CDS YP_002414859.1 218707340 7156149 complement(4357324..4358202) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; 2-oxo-3-deoxygalactonate kinase 4358202 dgoK 7156149 dgoK Escherichia coli UMN026 2-oxo-3-deoxygalactonate kinase YP_002414859.1 4357324 R 585056 CDS YP_002414860.1 218707341 7156151 complement(4358199..4358888) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4358888 dgoR 7156151 dgoR Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002414860.1 4358199 R 585056 CDS YP_002414861.1 218707342 7156152 4359049..4359822 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 4359822 yidX 7156152 yidX Escherichia coli UMN026 hypothetical protein YP_002414861.1 4359049 D 585056 CDS YP_002414862.1 218707343 7159266 complement(4359866..4360678) 1 NC_011751.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4360678 yidA 7159266 yidA Escherichia coli UMN026 sugar phosphatase YP_002414862.1 4359866 R 585056 CDS YP_002414863.1 218707344 7159251 complement(4360793..4361191) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4361191 yidB 7159251 yidB Escherichia coli UMN026 hypothetical protein YP_002414863.1 4360793 R 585056 CDS YP_002414864.1 218707345 7159252 complement(4361431..4363845) 1 NC_011751.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4363845 gyrB 7159252 gyrB Escherichia coli UMN026 DNA gyrase subunit B YP_002414864.1 4361431 R 585056 CDS YP_002414865.1 218707346 7156632 complement(4363874..4364947) 1 NC_011751.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4364947 recF 7156632 recF Escherichia coli UMN026 recombination protein F YP_002414865.1 4363874 R 585056 CDS YP_002414866.1 218707347 7157641 complement(4364947..4366047) 1 NC_011751.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4366047 dnaN 7157641 dnaN Escherichia coli UMN026 DNA polymerase III subunit beta YP_002414866.1 4364947 R 585056 CDS YP_002414867.1 218707348 7156190 complement(4366052..4367455) 1 NC_011751.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4367455 dnaA 7156190 dnaA Escherichia coli UMN026 chromosomal replication initiation protein YP_002414867.1 4366052 R 585056 CDS YP_002414868.1 218707349 7156183 4368062..4368202 1 NC_011751.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4368202 rpmH 7156183 rpmH Escherichia coli UMN026 50S ribosomal protein L34 YP_002414868.1 4368062 D 585056 CDS YP_002414869.1 218707350 7157755 4368219..4368578 1 NC_011751.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4368578 rnpA 7157755 rnpA Escherichia coli UMN026 ribonuclease P YP_002414869.1 4368219 D 585056 CDS YP_002414870.1 218707351 7157716 4368542..4368799 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4368799 yidD 7157716 yidD Escherichia coli UMN026 hypothetical protein YP_002414870.1 4368542 D 585056 CDS YP_002414871.1 218707352 7159254 4368802..4370448 1 NC_011751.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 4370448 yidC 7159254 yidC Escherichia coli UMN026 putative inner membrane protein translocase component YidC YP_002414871.1 4368802 D 585056 CDS YP_002414872.1 218707353 7159253 4370554..4371918 1 NC_011751.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4371918 trmE 7159253 trmE Escherichia coli UMN026 tRNA modification GTPase TrmE YP_002414872.1 4370554 D 585056 CDS YP_002414873.1 218707354 7158114 4372160..4372234 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; tryptophanase leader peptide 4372234 tnaC 7158114 tnaC Escherichia coli UMN026 tryptophanase leader peptide YP_002414873.1 4372160 D 585056 CDS YP_002414874.1 218707355 7158080 4372455..4373870 1 NC_011751.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4373870 tnaA 7158080 tnaA Escherichia coli UMN026 tryptophanase YP_002414874.1 4372455 D 585056 CDS YP_002414875.1 218707356 7158078 4373961..4375208 1 NC_011751.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4375208 tnaB 7158078 tnaB Escherichia coli UMN026 tryptophan permease TnaB YP_002414875.1 4373961 D 585056 CDS YP_002414876.1 218707357 7158079 4375341..4376516 1 NC_011751.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4376516 mdtL 7158079 mdtL Escherichia coli UMN026 multidrug efflux system protein MdtL YP_002414876.1 4375341 D 585056 CDS YP_002414877.1 218707358 7157089 4376491..4377450 1 NC_011751.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4377450 yidZ 7157089 yidZ Escherichia coli UMN026 DNA-binding transcriptional regulator YidZ YP_002414877.1 4376491 D 585056 CDS YP_002414878.1 218707359 7159267 4377595..4378356 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphopantetheinyl transferase 4378356 yieE 7159267 yieE Escherichia coli UMN026 putative phosphopantetheinyl transferase YP_002414878.1 4377595 D 585056 CDS YP_002414879.1 218707360 7159268 4378378..4378944 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme; chromate reductase, Class I, flavoprotein 4378944 yieF 7159268 yieF Escherichia coli UMN026 chromate reductase, Class I, flavoprotein YP_002414879.1 4378378 D 585056 CDS YP_002414880.1 218707361 7159269 complement(4378998..4380335) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4380335 yieG 7159269 yieG Escherichia coli UMN026 hypothetical protein YP_002414880.1 4378998 R 585056 CDS YP_002414881.1 218707362 7159270 4380502..4381167 1 NC_011751.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4381167 yieH 7159270 yieH Escherichia coli UMN026 6-phosphogluconate phosphatase YP_002414881.1 4380502 D 585056 CDS YP_002414882.1 218707363 7159271 complement(4381304..4383712) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4383712 7159271 ECUMN_4247 Escherichia coli UMN026 hypothetical protein YP_002414882.1 4381304 R 585056 CDS YP_002414883.1 218707364 7155450 4384018..4385205 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4385205 7155450 ECUMN_4248 Escherichia coli UMN026 hypothetical protein YP_002414883.1 4384018 D 585056 CDS YP_002414884.1 218707365 7155451 complement(4385675..4388194) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4388194 7155451 ECUMN_4249 Escherichia coli UMN026 hypothetical protein YP_002414884.1 4385675 R 585056 CDS YP_002414885.1 218707366 7155452 complement(4388592..4389317) 1 NC_011751.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4389317 phoU 7155452 phoU Escherichia coli UMN026 transcriptional regulator PhoU YP_002414885.1 4388592 R 585056 CDS YP_002414886.1 218707367 7157462 complement(4389332..4390105) 1 NC_011751.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4390105 pstB 7157462 pstB Escherichia coli UMN026 phosphate transporter ATP-binding protein YP_002414886.1 4389332 R 585056 CDS YP_002414887.1 218707368 7157558 complement(4390196..4391086) 1 NC_011751.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate permease PtsA 4391086 pstA 7157558 pstA Escherichia coli UMN026 phosphate permease PtsA YP_002414887.1 4390196 R 585056 CDS YP_002414888.1 218707369 7157557 complement(4391086..4392045) 1 NC_011751.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate permease PstC 4392045 pstC 7157557 pstC Escherichia coli UMN026 phosphate permease PstC YP_002414888.1 4391086 R 585056 CDS YP_002414889.1 218707370 7157559 complement(4392133..4393173) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter; phosphate ABC transporter periplasmic substrate-binding protein PstS 4393173 pstS 7157559 pstS Escherichia coli UMN026 phosphate ABC transporter periplasmic substrate-binding protein PstS YP_002414889.1 4392133 R 585056 CDS YP_002414890.1 218707371 7157560 complement(4393421..4394491) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12438351, 7721701, 16128397; Product type ps : putative structure; putative fimbrial protein LpfD 4394491 lpfD 7157560 lpfD Escherichia coli UMN026 putative fimbrial protein LpfD YP_002414890.1 4393421 R 585056 CDS YP_002414891.1 218707372 7157004 complement(4394502..4397024) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7721701, 16128397; Product type pt : putative transporter; putative fimbrial usher 4397024 lpfC 7157004 lpfC Escherichia coli UMN026 putative fimbrial usher YP_002414891.1 4394502 R 585056 CDS YP_002414892.1 218707373 7157003 complement(4397049..4397780) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16128397, 12438351; Product type pc : putative carrier; putative fimbrial chaperone protein 4397780 lfpB 7157003 lfpB Escherichia coli UMN026 putative fimbrial chaperone protein YP_002414892.1 4397049 R 585056 CDS YP_002414893.1 218707374 7156975 complement(4397828..4398400) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16125910, 12438351; Product type ps : putative structure; putative major fimbrial subunit 4398400 lpfA 7156975 lpfA Escherichia coli UMN026 putative major fimbrial subunit YP_002414893.1 4397828 R 585056 CDS YP_002414894.1 218707375 7157002 complement(4398708..4400537) 1 NC_011751.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4400537 glmS 7157002 glmS Escherichia coli UMN026 glucosamine--fructose-6-phosphate aminotransferase YP_002414894.1 4398708 R 585056 CDS YP_002414895.1 218707376 7156546 complement(4400699..4402069) 1 NC_011751.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4402069 glmU 7156546 glmU Escherichia coli UMN026 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002414895.1 4400699 R 585056 CDS YP_002414896.1 218707377 7156547 complement(4402420..4402839) 1 NC_011751.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4402839 atpC 7156547 atpC Escherichia coli UMN026 F0F1 ATP synthase subunit epsilon YP_002414896.1 4402420 R 585056 CDS YP_002414897.1 218707378 7155835 complement(4402860..4404242) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4404242 atpD 7155835 atpD Escherichia coli UMN026 F0F1 ATP synthase subunit beta YP_002414897.1 4402860 R 585056 CDS YP_002414898.1 218707379 7155836 complement(4404269..4405132) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4405132 atpG 7155836 atpG Escherichia coli UMN026 F0F1 ATP synthase subunit gamma YP_002414898.1 4404269 R 585056 CDS YP_002414899.1 218707380 7155839 complement(4405183..4406724) 1 NC_011751.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4406724 atpA 7155839 atpA Escherichia coli UMN026 F0F1 ATP synthase subunit alpha YP_002414899.1 4405183 R 585056 CDS YP_002414900.1 218707381 7155833 complement(4406737..4407270) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4407270 atpH 7155833 atpH Escherichia coli UMN026 F0F1 ATP synthase subunit delta YP_002414900.1 4406737 R 585056 CDS YP_002414901.1 218707382 7155840 complement(4407285..4407755) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4407755 atpF 7155840 atpF Escherichia coli UMN026 F0F1 ATP synthase subunit B YP_002414901.1 4407285 R 585056 CDS YP_002414902.1 218707383 7155838 complement(4407817..4408056) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4408056 atpE 7155838 atpE Escherichia coli UMN026 F0F1 ATP synthase subunit C YP_002414902.1 4407817 R 585056 CDS YP_002414903.1 218707384 7155837 complement(4408103..4408918) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4408918 atpB 7155837 atpB Escherichia coli UMN026 F0F1 ATP synthase subunit A YP_002414903.1 4408103 R 585056 CDS YP_002414904.1 218707385 7155834 complement(4408927..4409307) 1 NC_011751.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4409307 atpI 7155834 atpI Escherichia coli UMN026 F0F1 ATP synthase subunit I YP_002414904.1 4408927 R 585056 CDS YP_002414905.1 218707386 7155841 complement(4409924..4410547) 1 NC_011751.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4410547 gidB 7155841 gidB Escherichia coli UMN026 16S rRNA methyltransferase GidB YP_002414905.1 4409924 R 585056 CDS YP_002414906.1 218707387 7156529 complement(4410611..4412500) 1 NC_011751.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4412500 gidA 7156529 gidA Escherichia coli UMN026 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_002414906.1 4410611 R 585056 CDS YP_002414907.1 218707388 7156528 complement(4412879..4413322) 1 NC_011751.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4413322 mioC 7156528 mioC Escherichia coli UMN026 flavodoxin YP_002414907.1 4412879 R 585056 CDS YP_002414908.1 218707389 7157136 complement(4413412..4413870) 1 NC_011751.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4413870 asnC 7157136 asnC Escherichia coli UMN026 DNA-binding transcriptional regulator AsnC YP_002414908.1 4413412 R 585056 CDS YP_002414909.1 218707390 7155815 4414022..4415014 1 NC_011751.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4415014 asnA 7155815 asnA Escherichia coli UMN026 asparagine synthetase AsnA YP_002414909.1 4414022 D 585056 CDS YP_002414910.1 218707391 7155813 complement(4415019..4416470) 1 NC_011751.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4416470 yieM 7155813 yieM Escherichia coli UMN026 hypothetical protein YP_002414910.1 4415019 R 585056 CDS YP_002414911.1 218707392 7159272 complement(4416464..4417960) 1 NC_011751.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4417960 ravA 7159272 ravA Escherichia coli UMN026 regulatory ATPase RavA YP_002414911.1 4416464 R 585056 CDS YP_002414912.1 218707393 7157618 4418183..4420051 1 NC_011751.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4420051 trkD 7157618 trkD Escherichia coli UMN026 potassium transport protein Kup YP_002414912.1 4418183 D 585056 CDS YP_002414913.1 218707394 7158109 4420218..4420637 1 NC_011751.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4420637 rbsD 7158109 rbsD Escherichia coli UMN026 D-ribose pyranase YP_002414913.1 4420218 D 585056 CDS YP_002414914.1 218707395 7157625 4420645..4422150 1 NC_011751.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4422150 rbsA 7157625 rbsA Escherichia coli UMN026 D-ribose transporter ATP binding protein YP_002414914.1 4420645 D 585056 CDS YP_002414915.1 218707396 7157622 4422155..4423120 1 NC_011751.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 4423120 rbsC 7157622 rbsC Escherichia coli UMN026 ribose ABC transporter permease protein YP_002414915.1 4422155 D 585056 CDS YP_002414916.1 218707397 7157624 4423145..4424035 1 NC_011751.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4424035 rbsB 7157624 rbsB Escherichia coli UMN026 D-ribose transporter subunit RbsB YP_002414916.1 4423145 D 585056 CDS YP_002414917.1 218707398 7157623 4424161..4425090 1 NC_011751.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4425090 rbsK 7157623 rbsK Escherichia coli UMN026 ribokinase YP_002414917.1 4424161 D 585056 CDS YP_002414918.1 218707399 7157626 4425094..4426086 1 NC_011751.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4426086 rbsR 7157626 rbsR Escherichia coli UMN026 transcriptional repressor RbsR YP_002414918.1 4425094 D 585056 CDS YP_002414919.1 218707400 7157627 complement(4426052..4427479) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 20218988, 12107133; Product type t : transporter; multidrug or homocysteine efflux system 4427479 hsrA 7157627 hsrA Escherichia coli UMN026 multidrug or homocysteine efflux system YP_002414919.1 4426052 R 585056 CDS YP_002414920.1 218707401 7156725 complement(4427502..4428194) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4428194 yieP 7156725 yieP Escherichia coli UMN026 putative transcriptional regulator YP_002414920.1 4427502 R 585056 CDS YP_002414921.1 218707402 7155593 complement(4433993..4434832) 1 NC_011751.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4434832 hdfR 7155593 hdfR Escherichia coli UMN026 transcriptional regulator HdfR YP_002414921.1 4433993 R 585056 CDS YP_002414922.1 218707403 7156647 4434951..4435289 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4435289 yifE 7156647 yifE Escherichia coli UMN026 hypothetical protein YP_002414922.1 4434951 D 585056 CDS YP_002414923.1 218707404 7159275 complement(4435315..4436865) 1 NC_011751.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease 4436865 yifB 7159275 yifB Escherichia coli UMN026 putative ATP-dependent protease YP_002414923.1 4435315 R 585056 CDS YP_002414924.1 218707405 7159274 4437188..4437286 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvG operon leader peptide 4437286 ilvL 7159274 ilvL Escherichia coli UMN026 ilvG operon leader peptide YP_002414924.1 4437188 D 585056 CDS YP_002414925.1 218707406 7156805 4437426..4439072 1 NC_011751.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4439072 ilvG 7156805 ilvG Escherichia coli UMN026 acetolactate synthase 2 catalytic subunit YP_002414925.1 4437426 D 585056 CDS YP_002414926.1 218707407 7156802 4439069..4439332 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme; acetolactate synthase 2 regulatory subunit 4439332 ilvM 7156802 ilvM Escherichia coli UMN026 acetolactate synthase 2 regulatory subunit YP_002414926.1 4439069 D 585056 CDS YP_002414927.1 218707408 7156806 4439352..4440281 1 NC_011751.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4440281 ilvE 7156806 ilvE Escherichia coli UMN026 branched-chain amino acid aminotransferase YP_002414927.1 4439352 D 585056 CDS YP_002414928.1 218707409 7156801 4440346..4442196 1 NC_011751.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4442196 ilvD 7156801 ilvD Escherichia coli UMN026 dihydroxy-acid dehydratase YP_002414928.1 4440346 D 585056 CDS YP_002414929.1 218707410 7156800 4442199..4443743 1 NC_011751.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4443743 ilvA 7156800 ilvA Escherichia coli UMN026 threonine dehydratase YP_002414929.1 4442199 D 585056 CDS YP_002414930.1 218707411 7156797 complement(4443740..4444714) 1 NC_011751.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4444714 ilvY 7156797 ilvY Escherichia coli UMN026 DNA-binding transcriptional regulator IlvY YP_002414930.1 4443740 R 585056 CDS YP_002414931.1 218707412 7156808 4444780..4446255 1 NC_011751.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4446255 ilvC 7156808 ilvC Escherichia coli UMN026 ketol-acid reductoisomerase YP_002414931.1 4444780 D 585056 CDS YP_002414932.1 218707413 7156799 complement(4446301..4446582) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C 4446582 ppiC 7156799 ppiC Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase C YP_002414932.1 4446301 R 585056 CDS YP_002414933.1 218707414 7157507 4446669..4448690 1 NC_011751.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4448690 rep 7157507 rep Escherichia coli UMN026 ATP-dependent DNA helicase Rep YP_002414933.1 4446669 D 585056 CDS YP_002414934.1 218707415 7157652 complement(4448737..4450221) 1 NC_011751.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 4450221 gpp 7157652 gpp Escherichia coli UMN026 guanosine pentaphosphate phosphohydrolase YP_002414934.1 4448737 R 585056 CDS YP_002414935.1 218707416 7156606 complement(4450357..4451622) 1 NC_011751.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4451622 rhlB 7156606 rhlB Escherichia coli UMN026 ATP-dependent RNA helicase RhlB YP_002414935.1 4450357 R 585056 CDS YP_002414936.1 218707417 7157675 4451753..4452082 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier; thioredoxin 4452082 trxA 7157675 trxA Escherichia coli UMN026 thioredoxin YP_002414936.1 4451753 D 585056 CDS YP_002414937.1 218707418 7158129 4452223..4452324 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; putative rho operon leader peptide 4452324 rhoL 7158129 rhoL Escherichia coli UMN026 putative rho operon leader peptide YP_002414937.1 4452223 D 585056 CDS YP_002414938.1 218707419 7157678 4452409..4453668 1 NC_011751.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4453668 rho 7157678 rho Escherichia coli UMN026 transcription termination factor Rho YP_002414938.1 4452409 D 585056 CDS YP_002414939.1 218707420 7157677 4453678..4453896 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4453896 7157677 ECUMN_4308 Escherichia coli UMN026 hypothetical protein YP_002414939.1 4453678 D 585056 CDS YP_002414940.1 218707421 7155453 4453908..4455011 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme; UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase 4455011 rfe 7155453 rfe Escherichia coli UMN026 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase YP_002414940.1 4453908 D 585056 CDS YP_002414941.1 218707422 7157660 4455023..4456069 1 NC_011751.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4456069 wzzE 7157660 wzzE Escherichia coli UMN026 lipopolysaccharide biosynthesis protein WzzE YP_002414941.1 4455023 D 585056 CDS YP_002414942.1 218707423 7158241 4456125..4457255 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme; UDP-N-acetyl glucosamine-2-epimerase 4457255 rffE 7158241 rffE Escherichia coli UMN026 UDP-N-acetyl glucosamine-2-epimerase YP_002414942.1 4456125 D 585056 CDS YP_002414943.1 218707424 7157664 4457252..4458514 1 NC_011751.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4458514 wecC 7157664 wecC Escherichia coli UMN026 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002414943.1 4457252 D 585056 CDS YP_002414944.1 218707425 7157663 4458514..4459581 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase 4459581 rffG 7157663 rffG Escherichia coli UMN026 dTDP-glucose 4,6-dehydratase YP_002414944.1 4458514 D 585056 CDS YP_002414945.1 218707426 7157665 4459600..4460481 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme; glucose-1-phosphate thymidylyltransferase 4460481 rffH 7157665 rffH Escherichia coli UMN026 glucose-1-phosphate thymidylyltransferase YP_002414945.1 4459600 D 585056 CDS YP_002414946.1 218707427 7157666 4460459..4461133 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme; TDP-fucosamine acetyltransferase 4461133 rffC 7157666 rffC Escherichia coli UMN026 TDP-fucosamine acetyltransferase YP_002414946.1 4460459 D 585056 CDS YP_002414947.1 218707428 7157662 4461138..4462268 1 NC_011751.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4462268 rffA 7157662 rffA Escherichia coli UMN026 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002414947.1 4461138 D 585056 CDS YP_002414948.1 218707429 7157661 4462270..4463520 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter; O-antigen translocase 4463520 wzxE 7157661 wzxE Escherichia coli UMN026 O-antigen translocase YP_002414948.1 4462270 D 585056 CDS YP_002414949.1 218707430 7158239 4463517..4464596 1 NC_011751.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4464596 rffT 7158239 rffT Escherichia coli UMN026 4-alpha-L-fucosyltransferase YP_002414949.1 4463517 D 585056 CDS YP_002414950.1 218707431 7157668 4464593..4465945 1 NC_011751.1 enterobacterial common antigen polymerase; putative common antigen polymerase 4465945 wzyE 7157668 wzyE Escherichia coli UMN026 putative common antigen polymerase YP_002414950.1 4464593 D 585056 CDS YP_002414951.1 218707432 7158240 4465948..4466688 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 4466688 rffM 7158240 rffM Escherichia coli UMN026 putative UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002414951.1 4465948 D 585056 CDS YP_002414952.1 218707433 7157667 4466879..4468264 1 NC_011751.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 4468264 yifK 7157667 yifK Escherichia coli UMN026 putative transport protein YifK YP_002414952.1 4466879 D 585056 CDS YP_002414953.1 218707434 7155597 4468950..4470185 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : putative regulator; regulator of arylsulfatase activity 4470185 aslB 7155597 aslB Escherichia coli UMN026 regulator of arylsulfatase activity YP_002414953.1 4468950 D 585056 CDS YP_002414954.1 218707435 7155811 complement(4470287..4471942) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme; arylsulfatase-like enzyme 4471942 aslA 7155811 aslA Escherichia coli UMN026 arylsulfatase-like enzyme YP_002414954.1 4470287 R 585056 CDS YP_002414955.1 218707436 7157856 complement(4472621..4473817) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : putative enzyme; putative protoheme IX biogenesis protein 4473817 hemY 7157856 hemY Escherichia coli UMN026 putative protoheme IX biogenesis protein YP_002414955.1 4472621 R 585056 CDS YP_002414956.1 218707437 7156661 complement(4473820..4475031) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : putative enzyme; putative uroporphyrinogen III C-methyltransferase 4475031 hemX 7156661 hemX Escherichia coli UMN026 putative uroporphyrinogen III C-methyltransferase YP_002414956.1 4473820 R 585056 CDS YP_002414957.1 218707438 7156660 complement(4475053..4475793) 1 NC_011751.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4475793 hemD 7156660 hemD Escherichia coli UMN026 uroporphyrinogen-III synthase YP_002414957.1 4475053 R 585056 CDS YP_002414958.1 218707439 7156653 complement(4475790..4476731) 1 NC_011751.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4476731 hemC 7156653 hemC Escherichia coli UMN026 porphobilinogen deaminase YP_002414958.1 4475790 R 585056 CDS YP_002414959.1 218707440 7156652 4477118..4479664 1 NC_011751.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4479664 cyaA 7156652 cyaA Escherichia coli UMN026 adenylate cyclase YP_002414959.1 4477118 D 585056 CDS YP_002414960.1 218707441 7156060 complement(4479704..4480024) 1 NC_011751.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4480024 cyaY 7156060 cyaY Escherichia coli UMN026 frataxin-like protein YP_002414960.1 4479704 R 585056 CDS YP_002414961.1 218707442 7156061 4480490..4480693 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4480693 yifL 7156061 yifL Escherichia coli UMN026 putative lipoprotein YP_002414961.1 4480490 D 585056 CDS YP_002414962.1 218707443 7159277 4480730..4481554 1 NC_011751.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4481554 dapF 7159277 dapF Escherichia coli UMN026 diaminopimelate epimerase YP_002414962.1 4480730 D 585056 CDS YP_002414963.1 218707444 7156111 4481551..4482258 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4482258 yigA 7156111 yigA Escherichia coli UMN026 hypothetical protein YP_002414963.1 4481551 D 585056 CDS YP_002414964.1 218707445 7159278 4482255..4483151 1 NC_011751.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4483151 xerC 7159278 xerC Escherichia coli UMN026 site-specific tyrosine recombinase XerC YP_002414964.1 4482255 D 585056 CDS YP_002414965.1 218707446 7158246 4483151..4483867 1 NC_011751.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4483867 yigB 7158246 yigB Escherichia coli UMN026 flavin mononucleotide phosphatase YP_002414965.1 4483151 D 585056 CDS YP_002414966.1 218707447 7159279 4483951..4486113 1 NC_011751.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4486113 uvrD 7159279 uvrD Escherichia coli UMN026 DNA-dependent helicase II YP_002414966.1 4483951 D 585056 CDS YP_002414967.1 218707448 7155455 complement(4487143..4487907) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4487907 yigE 7155455 yigE Escherichia coli UMN026 hypothetical protein YP_002414967.1 4487143 R 585056 CDS YP_002414968.1 218707449 7159280 4488277..4489227 1 NC_011751.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4489227 corA 7159280 corA Escherichia coli UMN026 magnesium/nickel/cobalt transporter CorA YP_002414968.1 4488277 D 585056 CDS YP_002414969.1 218707450 7155999 complement(4489270..4489650) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; Product type pm : putative membrane component; hypothetical protein 4489650 yigF 7155999 yigF Escherichia coli UMN026 hypothetical protein YP_002414969.1 4489270 R 585056 CDS YP_002414970.1 218707451 7159281 complement(4489664..4490044) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4490044 yigG 7159281 yigG Escherichia coli UMN026 hypothetical protein YP_002414970.1 4489664 R 585056 CDS YP_002414971.1 218707452 7159282 complement(4490139..4491029) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chloramphenicol resistance permease 4491029 rarD 7159282 rarD Escherichia coli UMN026 putative chloramphenicol resistance permease YP_002414971.1 4490139 R 585056 CDS YP_002414972.1 218707453 7157617 complement(4491081..4491548) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4491548 yigI 7157617 yigI Escherichia coli UMN026 hypothetical protein YP_002414972.1 4491081 R 585056 CDS YP_002414973.1 218707454 7159283 4491713..4492582 1 NC_011751.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4492582 pldA 7159283 pldA Escherichia coli UMN026 phospholipase A YP_002414973.1 4491713 D 585056 CDS YP_002414974.1 218707455 7157470 4492715..4494544 1 NC_011751.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4494544 recQ 7157470 recQ Escherichia coli UMN026 ATP-dependent DNA helicase RecQ YP_002414974.1 4492715 D 585056 CDS YP_002414975.1 218707456 7157646 4494608..4495228 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter; threonine efflux system 4495228 rhtC 7157646 rhtC Escherichia coli UMN026 threonine efflux system YP_002414975.1 4494608 D 585056 CDS YP_002414976.1 218707457 7157681 complement(4495290..4495910) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter; homoserine/homoserine lactone efflux protein 4495910 rhtB 7157681 rhtB Escherichia coli UMN026 homoserine/homoserine lactone efflux protein YP_002414976.1 4495290 R 585056 CDS YP_002414977.1 218707458 7157680 4496021..4497043 1 NC_011751.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4497043 pldB 7157680 pldB Escherichia coli UMN026 lysophospholipase L2 YP_002414977.1 4496021 D 585056 CDS YP_002414978.1 218707459 7157471 4497051..4497851 1 NC_011751.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 4497851 yigL 7157471 yigL Escherichia coli UMN026 putative sugar phosphatase YP_002414978.1 4497051 D 585056 CDS YP_002414979.1 218707460 7159284 4497927..4498826 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4498826 yigM 7159284 yigM Escherichia coli UMN026 hypothetical protein YP_002414979.1 4497927 D 585056 CDS YP_002414980.1 218707461 7159285 complement(4498714..4499667) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator; DNA-binding transcriptional activator, homocysteine-binding 4499667 metR 7159285 metR Escherichia coli UMN026 DNA-binding transcriptional activator, homocysteine-binding YP_002414980.1 4498714 R 585056 CDS YP_002414981.1 218707462 7157113 4499903..4502164 1 NC_011751.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4502164 metE 7157113 metE Escherichia coli UMN026 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_002414981.1 4499903 D 585056 CDS YP_002414982.1 218707463 7157103 complement(4502203..4503018) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : putative enzyme; putative hydrolase 4503018 ysgA 7157103 ysgA Escherichia coli UMN026 putative hydrolase YP_002414982.1 4502203 R 585056 CDS YP_002414983.1 218707464 7159665 4503280..4504041 1 NC_011751.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4504041 udp 7159665 udp Escherichia coli UMN026 uridine phosphorylase YP_002414983.1 4503280 D 585056 CDS YP_002414984.1 218707465 7158163 4504182..4505609 1 NC_011751.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4505609 rmuC 7158163 rmuC Escherichia coli UMN026 DNA recombination protein RmuC YP_002414984.1 4504182 D 585056 CDS YP_002414985.1 218707466 7157704 4505704..4506459 1 NC_011751.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4506459 ubiE 7157704 ubiE Escherichia coli UMN026 ubiquinone/menaquinone biosynthesis methyltransferase YP_002414985.1 4505704 D 585056 CDS YP_002414986.1 218707467 7158156 4506473..4507078 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4507078 yigP 7158156 yigP Escherichia coli UMN026 hypothetical protein YP_002414986.1 4506473 D 585056 CDS YP_002414987.1 218707468 7159286 4507075..4508715 1 NC_011751.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 4508715 ubiB 7159286 ubiB Escherichia coli UMN026 putative ubiquinone biosynthesis protein UbiB YP_002414987.1 4507075 D 585056 CDS YP_002414988.1 218707469 7158153 4508794..4509063 1 NC_011751.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4509063 tatA 7158153 tatA Escherichia coli UMN026 twin arginine translocase protein A YP_002414988.1 4508794 D 585056 CDS YP_002414989.1 218707470 7158025 4509067..4509582 1 NC_011751.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4509582 tatB 7158025 tatB Escherichia coli UMN026 sec-independent translocase YP_002414989.1 4509067 D 585056 CDS YP_002414990.1 218707471 7158026 4509585..4510361 1 NC_011751.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4510361 tatC 7158026 tatC Escherichia coli UMN026 twin-arginine protein translocation system subunit TatC YP_002414990.1 4509585 D 585056 CDS YP_002414991.1 218707472 7158027 4510403..4511185 1 NC_011751.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4511185 tatD 7158027 tatD Escherichia coli UMN026 DNase TatD YP_002414991.1 4510403 D 585056 CDS YP_002414992.1 218707473 7158028 complement(4511182..4511670) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator; transcriptional activator RfaH 4511670 rfaH 7158028 rfaH Escherichia coli UMN026 transcriptional activator RfaH YP_002414992.1 4511182 R 585056 CDS YP_002414993.1 218707474 7157654 4511837..4513330 1 NC_011751.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate decarboxylase 4513330 ubiD 7157654 ubiD Escherichia coli UMN026 3-octaprenyl-4-hydroxybenzoate decarboxylase YP_002414993.1 4511837 D 585056 CDS YP_002414994.1 218707475 7158155 4513376..4514077 1 NC_011751.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4514077 fre 7158155 fre Escherichia coli UMN026 FMN reductase YP_002414994.1 4513376 D 585056 CDS YP_002414995.1 218707476 7156438 complement(4514268..4515431) 1 NC_011751.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4515431 fadA 7156438 fadA Escherichia coli UMN026 3-ketoacyl-CoA thiolase YP_002414995.1 4514268 R 585056 CDS YP_002414996.1 218707477 7156302 complement(4515441..4517630) 1 NC_011751.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4517630 fadB 7156302 fadB Escherichia coli UMN026 multifunctional fatty acid oxidation complex subunit alpha YP_002414996.1 4515441 R 585056 CDS YP_002414997.1 218707478 7156303 4517820..4519151 1 NC_011751.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4519151 pepQ 7156303 pepQ Escherichia coli UMN026 proline dipeptidase YP_002414997.1 4517820 D 585056 CDS YP_002414998.1 218707479 7157416 4519151..4519765 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : putative factor; hypothetical protein 4519765 yigZ 7157416 yigZ Escherichia coli UMN026 hypothetical protein YP_002414998.1 4519151 D 585056 CDS YP_002414999.1 218707480 7159287 4519804..4521255 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter; potassium transporter 4521255 trkH 7159287 trkH Escherichia coli UMN026 potassium transporter YP_002414999.1 4519804 D 585056 CDS YP_002415000.1 218707481 7158110 4521267..4521812 1 NC_011751.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4521812 hemG 7158110 hemG Escherichia coli UMN026 protoporphyrinogen oxidase YP_002415000.1 4521267 D 585056 CDS YP_002415001.1 218707482 7155562 complement(4527390..4527902) 1 NC_011751.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 4527902 mobB 7155562 mobB Escherichia coli UMN026 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002415001.1 4527390 R 585056 CDS YP_002415002.1 218707483 7157151 complement(4527899..4528483) 1 NC_011751.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 4528483 mobA 7157151 mobA Escherichia coli UMN026 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002415002.1 4527899 R 585056 CDS YP_002415003.1 218707484 7157150 4528553..4528822 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4528822 yihD 7157150 yihD Escherichia coli UMN026 hypothetical protein YP_002415003.1 4528553 D 585056 CDS YP_002415004.1 218707485 7159289 4528899..4529885 1 NC_011751.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4529885 yihE 7159289 yihE Escherichia coli UMN026 serine/threonine protein kinase YP_002415004.1 4528899 D 585056 CDS YP_002415005.1 218707486 7159290 4529902..4530528 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme; periplasmic protein disulfide isomerase I 4530528 dsbA 7159290 dsbA Escherichia coli UMN026 periplasmic protein disulfide isomerase I YP_002415005.1 4529902 D 585056 CDS YP_002415006.1 218707487 7156202 4530683..4532113 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4532113 yihF 7156202 yihF Escherichia coli UMN026 hypothetical protein YP_002415006.1 4530683 D 585056 CDS YP_002415007.1 218707488 7159291 complement(4532154..4533086) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 4533086 yihG 7159291 yihG Escherichia coli UMN026 putative acyltransferase YP_002415007.1 4532154 R 585056 CDS YP_002415008.1 218707489 7159292 4533450..4536236 1 NC_011751.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4536236 polA 7159292 polA Escherichia coli UMN026 DNA polymerase I YP_002415008.1 4533450 D 585056 CDS YP_002415009.1 218707490 7157963 complement(4536618..4537214) 1 NC_011751.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 4537214 engB 7157963 engB Escherichia coli UMN026 ribosome biogenesis GTP-binding protein YsxC YP_002415009.1 4536618 R 585056 CDS YP_002415010.1 218707491 7156045 4537832..4538341 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4538341 yihI 7156045 yihI Escherichia coli UMN026 hypothetical protein YP_002415010.1 4537832 D 585056 CDS YP_002415011.1 218707492 7159293 4538530..4539903 1 NC_011751.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4539903 hemN 7159293 hemN Escherichia coli UMN026 coproporphyrinogen III oxidase YP_002415011.1 4538530 D 585056 CDS YP_002415012.1 218707493 7156659 complement(4540315..4541724) 1 NC_011751.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4541724 glnG 7156659 glnG Escherichia coli UMN026 nitrogen regulation protein NR(I) YP_002415012.1 4540315 R 585056 CDS YP_002415013.1 218707494 7156552 complement(4541736..4542785) 1 NC_011751.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4542785 glnL 7156552 glnL Escherichia coli UMN026 nitrogen regulation protein NR(II) YP_002415013.1 4541736 R 585056 CDS YP_002415014.1 218707495 7156555 complement(4542959..4544368) 1 NC_011751.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4544368 glnA 7156555 glnA Escherichia coli UMN026 glutamine synthetase YP_002415014.1 4542959 R 585056 CDS YP_002415015.1 218707496 7156548 complement(4544502..4544648) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4544648 7156548 ECUMN_4394 Escherichia coli UMN026 hypothetical protein YP_002415015.1 4544502 R 585056 CDS YP_002415016.1 218707497 7155456 4544741..4546564 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor; GTP-binding protein 4546564 bipA 7155456 bipA Escherichia coli UMN026 GTP-binding protein YP_002415016.1 4544741 D 585056 CDS YP_002415017.1 218707498 7155882 4546781..4547491 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4547491 yihL 7155882 yihL Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415017.1 4546781 D 585056 CDS YP_002415018.1 218707499 7159295 complement(4547864..4548910) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS3 family 4548910 7159295 ECUMN_4398 Escherichia coli UMN026 transposase ORF B, IS3 family YP_002415018.1 4547864 R 585056 CDS YP_002415019.1 218707500 7155457 complement(4548730..4549077) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS3 family 4549077 7155457 ECUMN_4399 Escherichia coli UMN026 transposase ORF A, IS3 family YP_002415019.1 4548730 R 585056 CDS YP_002415020.1 218707501 7159296 4549842..4551107 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4551107 yihN 7159296 yihN Escherichia coli UMN026 putative transporter YP_002415020.1 4549842 D 585056 CDS YP_002415021.1 218707502 7159297 complement(4551199..4551891) 1 NC_011751.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L 4551891 ompL 7159297 ompL Escherichia coli UMN026 outer membrane porin L YP_002415021.1 4551199 R 585056 CDS YP_002415022.1 218707503 7157347 complement(4551958..4553361) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4553361 yihO 7157347 yihO Escherichia coli UMN026 putative transporter YP_002415022.1 4551958 R 585056 CDS YP_002415023.1 218707504 7159298 complement(4553402..4554808) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4554808 yihP 7159298 yihP Escherichia coli UMN026 putative transporter YP_002415023.1 4553402 R 585056 CDS YP_002415024.1 218707505 7159299 complement(4554833..4556869) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294295; Product type e : enzyme; alpha-glucosidase 4556869 yihQ 7159299 yihQ Escherichia coli UMN026 alpha-glucosidase YP_002415024.1 4554833 R 585056 CDS YP_002415025.1 218707506 7159300 complement(4557074..4557985) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldose-1-epimerase 4557985 yihR 7159300 yihR Escherichia coli UMN026 putative aldose-1-epimerase YP_002415025.1 4557074 R 585056 CDS YP_002415026.1 218707507 7159301 complement(4558044..4559285) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative glucosamine isomerase 4559285 yihS 7159301 yihS Escherichia coli UMN026 putative glucosamine isomerase YP_002415026.1 4558044 R 585056 CDS YP_002415027.1 218707508 7159302 complement(4559301..4560179) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative aldolase 4560179 yihT 7159302 yihT Escherichia coli UMN026 putative aldolase YP_002415027.1 4559301 R 585056 CDS YP_002415028.1 218707509 7159303 complement(4560203..4561099) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 4561099 yihU 7159303 yihU Escherichia coli UMN026 putative oxidoreductase YP_002415028.1 4560203 R 585056 CDS YP_002415029.1 218707510 7159304 4561267..4562163 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative sugar kinase 4562163 yihV 7159304 yihV Escherichia coli UMN026 putative sugar kinase YP_002415029.1 4561267 D 585056 CDS YP_002415030.1 218707511 7159305 4562197..4562982 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4562982 yihW 7159305 yihW Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415030.1 4562197 D 585056 CDS YP_002415031.1 218707512 7159306 4563081..4563680 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; phosphatase 4563680 yihX 7159306 yihX Escherichia coli UMN026 phosphatase YP_002415031.1 4563081 D 585056 CDS YP_002415032.1 218707513 7159307 4563674..4564546 1 NC_011751.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4564546 rbn 7159307 rbn Escherichia coli UMN026 ribonuclease BN YP_002415032.1 4563674 D 585056 CDS YP_002415033.1 218707514 7157621 4564543..4564980 1 NC_011751.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA (Tyr) deacylase 4564980 dtd 7157621 dtd Escherichia coli UMN026 D-tyrosyl-tRNA (Tyr) deacylase YP_002415033.1 4564543 D 585056 CDS YP_002415034.1 218707515 7156211 4564977..4565966 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 4565966 yiiD 7156211 yiiD Escherichia coli UMN026 putative acetyltransferase YP_002415034.1 4564977 D 585056 CDS YP_002415035.1 218707516 7159308 4566343..4568196 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4568196 7159308 ECUMN_4416 Escherichia coli UMN026 hypothetical protein YP_002415035.1 4566343 D 585056 CDS YP_002415036.1 218707517 7155459 4568246..4568347 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4568347 7155459 ECUMN_4417 Escherichia coli UMN026 hypothetical protein YP_002415036.1 4568246 D 585056 CDS YP_002415037.1 218707518 7155460 4568892..4569110 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4569110 yiiE 7155460 yiiE Escherichia coli UMN026 putative transcriptional regulator YP_002415037.1 4568892 D 585056 CDS YP_002415038.1 218707519 7159309 4569329..4569571 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4569571 yiiF 7159309 yiiF Escherichia coli UMN026 hypothetical protein YP_002415038.1 4569329 D 585056 CDS YP_002415039.1 218707520 7159310 complement(4569753..4570682) 1 NC_011751.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4570682 fdhE 7159310 fdhE Escherichia coli UMN026 formate dehydrogenase accessory protein FdhE YP_002415039.1 4569753 R 585056 CDS YP_002415040.1 218707521 7156314 complement(4570679..4571314) 1 NC_011751.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4571314 fdoI 7156314 fdoI Escherichia coli UMN026 formate dehydrogenase-O subunit gamma YP_002415040.1 4570679 R 585056 CDS YP_002415041.1 218707522 7156321 complement(4571311..4572213) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier; formate dehydrogenase-O, Fe-S subunit 4572213 fdoH 7156321 fdoH Escherichia coli UMN026 formate dehydrogenase-O, Fe-S subunit YP_002415041.1 4571311 R 585056 CDS YP_002415042.1 218707523 7156320 complement(4572226..4575276) 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-O, large subunit 4575276 fdoG 7156320 fdoG Escherichia coli UMN026 formate dehydrogenase-O, large subunit YP_002415042.1 4572226 R 585056 CDS YP_002415043.1 218707524 7156319 4575470..4576303 1 NC_011751.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4576303 fdhD 7156319 fdhD Escherichia coli UMN026 formate dehydrogenase accessory protein YP_002415043.1 4575470 D 585056 CDS YP_002415044.1 218707525 7159311 4577436..4578830 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component; putative glycoporin 4578830 7159311 ECUMN_4428 Escherichia coli UMN026 putative glycoporin YP_002415044.1 4577436 D 585056 CDS YP_002415045.1 218707526 7155461 complement(4578871..4579185) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme; L-rhamnose mutarotase 4579185 yiiL 7155461 yiiL Escherichia coli UMN026 L-rhamnose mutarotase YP_002415045.1 4578871 R 585056 CDS YP_002415046.1 218707527 7159312 complement(4579195..4580019) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme; rhamnulose-1-phosphate aldolase 4580019 rhaD 7159312 rhaD Escherichia coli UMN026 rhamnulose-1-phosphate aldolase YP_002415046.1 4579195 R 585056 CDS YP_002415047.1 218707528 7157671 complement(4580102..4581361) 1 NC_011751.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 4581361 rhaA 7157671 rhaA Escherichia coli UMN026 L-rhamnose isomerase YP_002415047.1 4580102 R 585056 CDS YP_002415048.1 218707529 7157669 complement(4581358..4582827) 1 NC_011751.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 4582827 rhaB 7157669 rhaB Escherichia coli UMN026 rhamnulokinase YP_002415048.1 4581358 R 585056 CDS YP_002415049.1 218707530 7157670 4583115..4583951 1 NC_011751.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4583951 rhaS 7157670 rhaS Escherichia coli UMN026 transcriptional activator RhaS YP_002415049.1 4583115 D 585056 CDS YP_002415050.1 218707531 7157673 4583935..4584873 1 NC_011751.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4584873 rhaR 7157673 rhaR Escherichia coli UMN026 transcriptional activator RhaR YP_002415050.1 4583935 D 585056 CDS YP_002415051.1 218707532 7157672 complement(4584870..4585904) 1 NC_011751.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 4585904 rhaT 7157672 rhaT Escherichia coli UMN026 rhamnose-proton symporter YP_002415051.1 4584870 R 585056 CDS YP_002415052.1 218707533 7157674 4586189..4586809 1 NC_011751.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4586809 sodA 7157674 sodA Escherichia coli UMN026 superoxide dismutase YP_002415052.1 4586189 D 585056 CDS YP_002415053.1 218707534 7157945 4587087..4588052 1 NC_011751.1 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4588052 kdgT 7157945 kdgT Escherichia coli UMN026 2-keto-3-deoxygluconate permease YP_002415053.1 4587087 D 585056 CDS YP_002415054.1 218707535 7156889 4588201..4588875 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4588875 yiiM 7156889 yiiM Escherichia coli UMN026 hypothetical protein YP_002415054.1 4588201 D 585056 CDS YP_002415055.1 218707536 7159313 complement(4588980..4590353) 1 NC_011751.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 4590353 cpxA 7159313 cpxA Escherichia coli UMN026 two-component sensor protein YP_002415055.1 4588980 R 585056 CDS YP_002415056.1 218707537 7156005 complement(4590350..4591048) 1 NC_011751.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 4591048 cpxR 7156005 cpxR Escherichia coli UMN026 DNA-binding transcriptional regulator CpxR YP_002415056.1 4590350 R 585056 CDS YP_002415057.1 218707538 7156007 4591198..4591698 1 NC_011751.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4591698 cpxP 7156007 cpxP Escherichia coli UMN026 periplasmic repressor CpxP YP_002415057.1 4591198 D 585056 CDS YP_002415058.1 218707539 7156006 4591847..4592749 1 NC_011751.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4592749 fieF 7156006 fieF Escherichia coli UMN026 ferrous iron efflux protein F YP_002415058.1 4591847 D 585056 CDS YP_002415059.1 218707540 7156353 4592930..4593892 1 NC_011751.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4593892 pfkA 7156353 pfkA Escherichia coli UMN026 6-phosphofructokinase YP_002415059.1 4592930 D 585056 CDS YP_002415060.1 218707541 7157419 4594212..4595201 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter; sulfate transporter subunit 4595201 sbp 7157419 sbp Escherichia coli UMN026 sulfate transporter subunit YP_002415060.1 4594212 D 585056 CDS YP_002415061.1 218707542 7157876 4595308..4596063 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase 4596063 cdh 7157876 cdh Escherichia coli UMN026 CDP-diacylglycerol pyrophosphatase YP_002415061.1 4595308 D 585056 CDS YP_002415062.1 218707543 7155938 complement(4596118..4596885) 1 NC_011751.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 4596885 tpiA 7155938 tpiA Escherichia coli UMN026 triosephosphate isomerase YP_002415062.1 4596118 R 585056 CDS YP_002415063.1 218707544 7158098 complement(4596993..4597592) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4597592 yiiQ 7158098 yiiQ Escherichia coli UMN026 hypothetical protein YP_002415063.1 4596993 R 585056 CDS YP_002415064.1 218707545 7159314 4597693..4598133 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4598133 yiiR 7159314 yiiR Escherichia coli UMN026 hypothetical protein YP_002415064.1 4597693 D 585056 CDS YP_002415065.1 218707546 7159315 4598345..4598644 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4598644 yiiS 7159315 yiiS Escherichia coli UMN026 hypothetical protein YP_002415065.1 4598345 D 585056 CDS YP_002415066.1 218707547 7159316 4598671..4599099 1 NC_011751.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4599099 yiiT 7159316 yiiT Escherichia coli UMN026 universal stress protein UspD YP_002415066.1 4598671 D 585056 CDS YP_002415067.1 218707548 7159317 complement(4599104..4599850) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme; ferredoxin-NADP reductase 4599850 fpr 7159317 fpr Escherichia coli UMN026 ferredoxin-NADP reductase YP_002415067.1 4599104 R 585056 CDS YP_002415068.1 218707549 7156432 complement(4599947..4600957) 1 NC_011751.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 4600957 glpX 7156432 glpX Escherichia coli UMN026 fructose 1,6-bisphosphatase II YP_002415068.1 4599947 R 585056 CDS YP_002415069.1 218707550 7156572 complement(4601092..4602600) 1 NC_011751.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 4602600 glpK 7156572 glpK Escherichia coli UMN026 glycerol kinase YP_002415069.1 4601092 R 585056 CDS YP_002415070.1 218707551 7156568 complement(4602623..4603468) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter; glycerol facilitator 4603468 glpF 7156568 glpF Escherichia coli UMN026 glycerol facilitator YP_002415070.1 4602623 R 585056 CDS YP_002415071.1 218707552 7156566 4603893..4604138 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4604138 yiiU 7156566 yiiU Escherichia coli UMN026 hypothetical protein YP_002415071.1 4603893 D 585056 CDS YP_002415072.1 218707553 7159318 complement(4604177..4604893) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4604893 7159318 ECUMN_4457 Escherichia coli UMN026 hypothetical protein YP_002415072.1 4604177 R 585056 CDS YP_002415073.1 218707554 7155462 complement(4604926..4605612) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4605612 7155462 ECUMN_4458 Escherichia coli UMN026 hypothetical protein YP_002415073.1 4604926 R 585056 CDS YP_002415074.1 218707555 7155463 complement(4605660..4606145) 1 NC_011751.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 4606145 rraA 7155463 rraA Escherichia coli UMN026 ribonuclease activity regulator protein RraA YP_002415074.1 4605660 R 585056 CDS YP_002415075.1 218707556 7157788 complement(4606238..4607164) 1 NC_011751.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4607164 menA 7157788 menA Escherichia coli UMN026 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002415075.1 4606238 R 585056 CDS YP_002415076.1 218707557 7157093 complement(4607231..4608562) 1 NC_011751.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 4608562 hslU 7157093 hslU Escherichia coli UMN026 ATP-dependent protease ATP-binding subunit HslU YP_002415076.1 4607231 R 585056 CDS YP_002415077.1 218707558 7156723 complement(4608572..4609102) 1 NC_011751.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 4609102 hslV 7156723 hslV Escherichia coli UMN026 ATP-dependent protease peptidase subunit YP_002415077.1 4608572 R 585056 CDS YP_002415078.1 218707559 7156724 complement(4609195..4610154) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process; essential cell division protein FtsN 4610154 ftsN 7156724 ftsN Escherichia coli UMN026 essential cell division protein FtsN YP_002415078.1 4609195 R 585056 CDS YP_002415079.1 218707560 7156463 complement(4610246..4611271) 1 NC_011751.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 4611271 cytR 7156463 cytR Escherichia coli UMN026 DNA-binding transcriptional regulator CytR YP_002415079.1 4610246 R 585056 CDS YP_002415080.1 218707561 7156096 complement(4611427..4613625) 1 NC_011751.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 4613625 priA 7156096 priA Escherichia coli UMN026 primosome assembly protein PriA YP_002415080.1 4611427 R 585056 CDS YP_002415081.1 218707562 7157522 4613828..4614040 1 NC_011751.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4614040 rpmE 7157522 rpmE Escherichia coli UMN026 50S ribosomal protein L31 YP_002415081.1 4613828 D 585056 CDS YP_002415082.1 218707563 7157752 complement(4614101..4614709) 1 NC_011751.1 member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase 4614709 yiiX 7157752 yiiX Escherichia coli UMN026 putative peptidoglycan peptidase YP_002415082.1 4614101 R 585056 CDS YP_002415083.1 218707564 7159319 complement(4614769..4615224) 1 NC_011751.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 4615224 metJ 7159319 metJ Escherichia coli UMN026 transcriptional repressor protein MetJ YP_002415083.1 4614769 R 585056 CDS YP_002415084.1 218707565 7157108 4615363..4616523 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87326410, 90148970, 3307782, 6361020, 9843488; Product type e : enzyme; cystathionine gamma-synthase, PLP-dependent 4616523 metB 7157108 metB Escherichia coli UMN026 cystathionine gamma-synthase, PLP-dependent YP_002415084.1 4615363 D 585056 CDS YP_002415085.1 218707566 7157101 4616526..4618958 1 NC_011751.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4618958 metL 7157101 metL Escherichia coli UMN026 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002415085.1 4616526 D 585056 CDS YP_002415086.1 218707567 7157110 complement(4618922..4620052) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4620052 7157110 ECUMN_4471 Escherichia coli UMN026 hypothetical protein YP_002415086.1 4618922 R 585056 CDS YP_002415087.1 218707568 7155464 4620185..4621738 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative phosphoesterase 4621738 7155464 ECUMN_4472 Escherichia coli UMN026 putative phosphoesterase YP_002415087.1 4620185 D 585056 CDS YP_002415088.1 218707569 7155465 4622120..4623010 1 NC_011751.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4623010 metF 7155465 metF Escherichia coli UMN026 5,10-methylenetetrahydrofolate reductase YP_002415088.1 4622120 D 585056 CDS YP_002415089.1 218707570 7157104 4623339..4625519 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme; catalase/hydroperoxidase HPI(I) 4625519 katG 7157104 katG Escherichia coli UMN026 catalase/hydroperoxidase HPI(I) YP_002415089.1 4623339 D 585056 CDS YP_002415090.1 218707571 7156882 4625612..4626517 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 4626517 yijE 7156882 yijE Escherichia coli UMN026 putative permease YP_002415090.1 4625612 D 585056 CDS YP_002415091.1 218707572 7159321 complement(4626544..4627161) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4627161 yijF 7159321 yijF Escherichia coli UMN026 hypothetical protein YP_002415091.1 4626544 R 585056 CDS YP_002415092.1 218707573 7159322 complement(4627492..4628595) 1 NC_011751.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 4628595 gldA 7159322 gldA Escherichia coli UMN026 glycerol dehydrogenase YP_002415092.1 4627492 R 585056 CDS YP_002415093.1 218707574 7156536 complement(4628606..4629268) 1 NC_011751.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 4629268 fsaB 7156536 fsaB Escherichia coli UMN026 fructose-6-phosphate aldolase YP_002415093.1 4628606 R 585056 CDS YP_002415094.1 218707575 7156453 complement(4629280..4631781) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter; putative PTS system Hpr component/enzyme I component/enzyme IIA component 4631781 ptsA 7156453 ptsA Escherichia coli UMN026 putative PTS system Hpr component/enzyme I component/enzyme IIA component YP_002415094.1 4629280 R 585056 CDS YP_002415095.1 218707576 7157565 4632090..4633169 1 NC_011751.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4633169 frwC 7157565 frwC Escherichia coli UMN026 putative fructose-like permease EIIC subunit 2 YP_002415095.1 4632090 D 585056 CDS YP_002415096.1 218707577 7156450 4633184..4633504 1 NC_011751.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4633504 frwB 7156450 frwB Escherichia coli UMN026 putative PTS system fructose-like transporter subunit EIIB YP_002415096.1 4633184 D 585056 CDS YP_002415097.1 218707578 7156449 4633555..4635852 1 NC_011751.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4635852 pflD 7156449 pflD Escherichia coli UMN026 putative formate acetyltransferase 2 YP_002415097.1 4633555 D 585056 CDS YP_002415098.1 218707579 7157424 4635818..4636696 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme; pyruvate formate lyase II activase 4636696 pflC 7157424 pflC Escherichia coli UMN026 pyruvate formate lyase II activase YP_002415098.1 4635818 D 585056 CDS YP_002415099.1 218707580 7157423 4636698..4637039 1 NC_011751.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4637039 frwD 7157423 frwD Escherichia coli UMN026 putative fructose-like phosphotransferase EIIB subunit 3 YP_002415099.1 4636698 D 585056 CDS YP_002415100.1 218707581 7156451 complement(4637026..4637877) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 4637877 yijO 7156451 yijO Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415100.1 4637026 R 585056 CDS YP_002415101.1 218707582 7159323 complement(4638103..4639836) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : putative membrane component; hypothetical protein 4639836 yijP 7159323 yijP Escherichia coli UMN026 hypothetical protein YP_002415101.1 4638103 R 585056 CDS YP_002415102.1 218707583 7159324 complement(4640019..4642670) 1 NC_011751.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4642670 ppc 7159324 ppc Escherichia coli UMN026 phosphoenolpyruvate carboxylase YP_002415102.1 4640019 R 585056 CDS YP_002415103.1 218707584 7157498 complement(4643082..4644233) 1 NC_011751.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4644233 argE 7157498 argE Escherichia coli UMN026 acetylornithine deacetylase YP_002415103.1 4643082 R 585056 CDS YP_002415104.1 218707585 7155772 4644387..4645391 1 NC_011751.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4645391 argC 7155772 argC Escherichia coli UMN026 N-acetyl-gamma-glutamyl-phosphate reductase YP_002415104.1 4644387 D 585056 CDS YP_002415105.1 218707586 7155770 4645402..4646175 1 NC_011751.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4646175 argB 7155770 argB Escherichia coli UMN026 acetylglutamate kinase YP_002415105.1 4645402 D 585056 CDS YP_002415106.1 218707587 7155769 4646236..4647609 1 NC_011751.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4647609 argH 7155769 argH Escherichia coli UMN026 argininosuccinate lyase YP_002415106.1 4646236 D 585056 CDS YP_002415107.1 218707588 7157371 4647876..4648793 1 NC_011751.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4648793 oxyR 7157371 oxyR Escherichia coli UMN026 DNA-binding transcriptional regulator OxyR YP_002415107.1 4647876 D 585056 CDS YP_002415108.1 218707589 7157370 complement(4648776..4650176) 1 NC_011751.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4650176 sthA 7157370 sthA Escherichia coli UMN026 soluble pyridine nucleotide transhydrogenase YP_002415108.1 4648776 R 585056 CDS YP_002415109.1 218707590 7157996 4650454..4651158 1 NC_011751.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4651158 fabR 7157996 fabR Escherichia coli UMN026 DNA-binding transcriptional repressor FabR YP_002415109.1 4650454 D 585056 CDS YP_002415110.1 218707591 7156300 4651158..4651517 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4651517 yijD 7156300 yijD Escherichia coli UMN026 hypothetical protein YP_002415110.1 4651158 D 585056 CDS YP_002415111.1 218707592 7159320 complement(4651557..4652657) 1 NC_011751.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4652657 trmA 7159320 trmA Escherichia coli UMN026 tRNA (uracil-5-)-methyltransferase YP_002415111.1 4651557 R 585056 CDS YP_002415112.1 218707593 7158111 4653026..4654870 1 NC_011751.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4654870 btuB 7158111 btuB Escherichia coli UMN026 vitamin B12/cobalamin outer membrane transporter YP_002415112.1 4653026 D 585056 CDS YP_002415113.1 218707594 7155894 4654803..4655672 1 NC_011751.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4655672 murI 7155894 murI Escherichia coli UMN026 glutamate racemase YP_002415113.1 4654803 D 585056 CDS YP_002415114.1 218707595 7155563 4661194..4662222 1 NC_011751.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4662222 murB 7155563 murB Escherichia coli UMN026 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002415114.1 4661194 D 585056 CDS YP_002415115.1 218707596 7157202 4662219..4663184 1 NC_011751.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4663184 birA 7157202 birA Escherichia coli UMN026 biotin--protein ligase YP_002415115.1 4662219 D 585056 CDS YP_002415116.1 218707597 7155883 complement(4663213..4664163) 1 NC_011751.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4664163 coaA 7155883 coaA Escherichia coli UMN026 pantothenate kinase YP_002415116.1 4663213 R 585056 CDS YP_002415117.1 218707598 7155605 4665081..4666265 1 NC_011751.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4666265 tufB 7155605 tufB Escherichia coli UMN026 elongation factor Tu YP_002415117.1 4665081 D 585056 CDS YP_002415118.1 218707599 7158140 4666495..4666878 1 NC_011751.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4666878 secE 7158140 secE Escherichia coli UMN026 preprotein translocase subunit SecE YP_002415118.1 4666495 D 585056 CDS YP_002415119.1 218707600 7157888 4666880..4667425 1 NC_011751.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4667425 nusG 7157888 nusG Escherichia coli UMN026 transcription antitermination protein NusG YP_002415119.1 4666880 D 585056 CDS YP_002415120.1 218707601 7157340 4667584..4668012 1 NC_011751.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4668012 rplK 7157340 rplK Escherichia coli UMN026 50S ribosomal protein L11 YP_002415120.1 4667584 D 585056 CDS YP_002415121.1 218707602 7157733 4668016..4668720 1 NC_011751.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4668720 rplA 7157733 rplA Escherichia coli UMN026 50S ribosomal protein L1 YP_002415121.1 4668016 D 585056 CDS YP_002415122.1 218707603 7157725 4669012..4669509 1 NC_011751.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4669509 rplJ 7157725 rplJ Escherichia coli UMN026 50S ribosomal protein L10 YP_002415122.1 4669012 D 585056 CDS YP_002415123.1 218707604 7157732 4669576..4669941 1 NC_011751.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4669941 rplL 7157732 rplL Escherichia coli UMN026 50S ribosomal protein L7/L12 YP_002415123.1 4669576 D 585056 CDS YP_002415124.1 218707605 7157734 4670261..4674289 1 NC_011751.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4674289 rpoB 7157734 rpoB Escherichia coli UMN026 DNA-directed RNA polymerase subunit beta YP_002415124.1 4670261 D 585056 CDS YP_002415125.1 218707606 7157758 4674366..4678589 1 NC_011751.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4678589 rpoC 7157758 rpoC Escherichia coli UMN026 DNA-directed RNA polymerase subunit beta' YP_002415125.1 4674366 D 585056 CDS YP_002415126.1 218707607 7157759 4678803..4679342 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264341, 92021792, 2160943; Product type f : factor; heat shock protein 4679342 htrC 7157759 htrC Escherichia coli UMN026 heat shock protein YP_002415126.1 4678803 D 585056 CDS YP_002415127.1 218707608 7157981 complement(4679752..4680885) 1 NC_011751.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4680885 thiH 7157981 thiH Escherichia coli UMN026 thiamine biosynthesis protein ThiH YP_002415127.1 4679752 R 585056 CDS YP_002415128.1 218707609 7158057 complement(4680882..4681652) 1 NC_011751.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4681652 thiG 7158057 thiG Escherichia coli UMN026 thiazole synthase YP_002415128.1 4680882 R 585056 CDS YP_002415129.1 218707610 7158056 complement(4681654..4681854) 1 NC_011751.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 4681854 thiS 7158056 thiS Escherichia coli UMN026 sulfur carrier protein ThiS YP_002415129.1 4681654 R 585056 CDS YP_002415130.1 218707611 7158063 complement(4681838..4682593) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme; thiamin (thiazole moiety) biosynthesis protein 4682593 thiF 7158063 thiF Escherichia coli UMN026 thiamin (thiazole moiety) biosynthesis protein YP_002415130.1 4681838 R 585056 CDS YP_002415131.1 218707612 7158055 complement(4682586..4683221) 1 NC_011751.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4683221 thiE 7158055 thiE Escherichia coli UMN026 thiamine-phosphate pyrophosphorylase YP_002415131.1 4682586 R 585056 CDS YP_002415132.1 218707613 7158054 complement(4683221..4685116) 1 NC_011751.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4685116 thiC 7158054 thiC Escherichia coli UMN026 thiamine biosynthesis protein ThiC YP_002415132.1 4683221 R 585056 CDS YP_002415133.1 218707614 7158052 complement(4685349..4685825) 1 NC_011751.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4685825 rsd 7158052 rsd Escherichia coli UMN026 anti-RNA polymerase sigma 70 factor YP_002415133.1 4685349 R 585056 CDS YP_002415134.1 218707615 7157791 4685920..4686693 1 NC_011751.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4686693 nudC 7157791 nudC Escherichia coli UMN026 NADH pyrophosphatase YP_002415134.1 4685920 D 585056 CDS YP_002415135.1 218707616 7157317 4686733..4687797 1 NC_011751.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4687797 hemE 7157317 hemE Escherichia coli UMN026 uroporphyrinogen decarboxylase YP_002415135.1 4686733 D 585056 CDS YP_002415136.1 218707617 7156654 4687807..4688478 1 NC_011751.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4688478 nfi 7156654 nfi Escherichia coli UMN026 endonuclease V YP_002415136.1 4687807 D 585056 CDS YP_002415137.1 218707618 7157265 4688521..4689111 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4689111 yjaG 7157265 yjaG Escherichia coli UMN026 hypothetical protein YP_002415137.1 4688521 D 585056 CDS YP_002415138.1 218707619 7159326 4689298..4689570 1 NC_011751.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4689570 hupA 7159326 hupA Escherichia coli UMN026 transcriptional regulator HU subunit alpha YP_002415138.1 4689298 D 585056 CDS YP_002415139.1 218707620 7156732 4689583..4690278 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4690278 yjaH 7156732 yjaH Escherichia coli UMN026 hypothetical protein YP_002415139.1 4689583 D 585056 CDS YP_002415140.1 218707621 7159327 complement(4690280..4690699) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : putative factor; zinc resistance protein 4690699 zraP 7159327 zraP Escherichia coli UMN026 zinc resistance protein YP_002415140.1 4690280 R 585056 CDS YP_002415141.1 218707622 7159692 4690937..4692313 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator; sensor protein ZraS 4692313 zraS 7159692 zraS Escherichia coli UMN026 sensor protein ZraS YP_002415141.1 4690937 D 585056 CDS YP_002415142.1 218707623 7159694 4692310..4693635 1 NC_011751.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4693635 zraR 7159694 zraR Escherichia coli UMN026 transcriptional regulatory protein ZraR YP_002415142.1 4692310 D 585056 CDS YP_002415143.1 218707624 7159693 complement(4693632..4694921) 1 NC_011751.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4694921 purD 7159693 purD Escherichia coli UMN026 phosphoribosylamine--glycine ligase YP_002415143.1 4693632 R 585056 CDS YP_002415144.1 218707625 7157575 complement(4694933..4696522) 1 NC_011751.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4696522 purH 7157575 purH Escherichia coli UMN026 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002415144.1 4694933 R 585056 CDS YP_002415145.1 218707626 7155564 complement(4702436..4702879) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; hypothetical protein 4702879 yjaB 7155564 yjaB Escherichia coli UMN026 hypothetical protein YP_002415145.1 4702436 R 585056 CDS YP_002415146.1 218707627 7159325 4703036..4703965 1 NC_011751.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4703965 metA 7159325 metA Escherichia coli UMN026 homoserine O-succinyltransferase YP_002415146.1 4703036 D 585056 CDS YP_002415147.1 218707628 7157100 4704234..4705835 1 NC_011751.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4705835 aceB 7157100 aceB Escherichia coli UMN026 malate synthase YP_002415147.1 4704234 D 585056 CDS YP_002415148.1 218707629 7155676 4705865..4707169 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme; isocitrate lyase 4707169 aceA 7155676 aceA Escherichia coli UMN026 isocitrate lyase YP_002415148.1 4705865 D 585056 CDS YP_002415149.1 218707630 7155675 4707218..4708954 1 NC_011751.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4708954 aceK 7155675 aceK Escherichia coli UMN026 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_002415149.1 4707218 D 585056 CDS YP_002415150.1 218707631 7155679 complement(4708923..4711109) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1995429, 8014990; Product type r : regulator; regulator of acetyl CoA synthetase 4711109 arpA 7155679 arpA Escherichia coli UMN026 regulator of acetyl CoA synthetase YP_002415150.1 4708923 R 585056 CDS YP_002415151.1 218707632 7155795 complement(4711426..4712250) 1 NC_011751.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR 4712250 iclR 7155795 iclR Escherichia coli UMN026 transcriptional repressor IclR YP_002415151.1 4711426 R 585056 CDS YP_002415152.1 218707633 7156786 4712450..4716133 1 NC_011751.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4716133 metH 7156786 metH Escherichia coli UMN026 B12-dependent methionine synthase YP_002415152.1 4712450 D 585056 CDS YP_002415153.1 218707634 7157106 4716353..4717984 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4717984 yjbB 7157106 yjbB Escherichia coli UMN026 putative transporter YP_002415153.1 4716353 D 585056 CDS YP_002415154.1 218707635 7159329 complement(4718074..4718763) 1 NC_011751.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E 4718763 pepE 7159329 pepE Escherichia coli UMN026 peptidase E YP_002415154.1 4718074 R 585056 CDS YP_002415155.1 218707636 7157413 complement(4719145..4720386) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme; L-sorbose 1-phosphate reductase 4720386 7157413 ECUMN_4548 Escherichia coli UMN026 L-sorbose 1-phosphate reductase YP_002415155.1 4719145 R 585056 CDS YP_002415156.1 218707637 7155466 complement(4720426..4721280) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IID component 4721280 7155466 ECUMN_4549 Escherichia coli UMN026 sorbose permease IID component YP_002415156.1 4720426 R 585056 CDS YP_002415157.1 218707638 7155467 complement(4721261..4722058) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IIC component (PTS system) 4722058 7155467 ECUMN_4550 Escherichia coli UMN026 sorbose permease IIC component (PTS system) YP_002415157.1 4721261 R 585056 CDS YP_002415158.1 218707639 7155468 complement(4722124..4722618) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter; sorbose-specific phosphotransferase enzyme IIB component (PTS system) 4722618 7155468 ECUMN_4551 Escherichia coli UMN026 sorbose-specific phosphotransferase enzyme IIB component (PTS system) YP_002415158.1 4722124 R 585056 CDS YP_002415159.1 218707640 7155469 complement(4722618..4723025) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter; sorbose-specific phosphotransferase enzyme IIA component (PTS system) 4723025 7155469 ECUMN_4552 Escherichia coli UMN026 sorbose-specific phosphotransferase enzyme IIA component (PTS system) YP_002415159.1 4722618 R 585056 CDS YP_002415160.1 218707641 7155470 complement(4723035..4723841) 1 NC_011751.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4723841 7155470 ECUMN_4553 Escherichia coli UMN026 sorbitol-6-phosphate 2-dehydrogenase YP_002415160.1 4723035 R 585056 CDS YP_002415161.1 218707642 7155471 complement(4723911..4724942) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator; sorbitol/sorbose operon activator 4724942 7155471 ECUMN_4554 Escherichia coli UMN026 sorbitol/sorbose operon activator YP_002415161.1 4723911 R 585056 CDS YP_002415162.1 218707643 7155472 4725206..4726078 1 NC_011751.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4726078 yjbC 7155472 yjbC Escherichia coli UMN026 23S rRNA pseudouridine synthase F YP_002415162.1 4725206 D 585056 CDS YP_002415163.1 218707644 7159330 complement(4726079..4726351) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4726351 yjbD 7159330 yjbD Escherichia coli UMN026 hypothetical protein YP_002415163.1 4726079 R 585056 CDS YP_002415164.1 218707645 7159331 complement(4726603..4727952) 1 NC_011751.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4727952 lysC 7159331 lysC Escherichia coli UMN026 aspartate kinase III YP_002415164.1 4726603 R 585056 CDS YP_002415165.1 218707646 7157030 4728477..4730126 1 NC_011751.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4730126 pgi 7157030 pgi Escherichia coli UMN026 glucose-6-phosphate isomerase YP_002415165.1 4728477 D 585056 CDS YP_002415166.1 218707647 7157426 complement(4730575..4730823) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4730823 7157426 ECUMN_4559 Escherichia coli UMN026 hypothetical protein YP_002415166.1 4730575 R 585056 CDS YP_002415167.1 218707648 7155473 4730950..4731588 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; putative lipoprotein 4731588 yjbF 7155473 yjbF Escherichia coli UMN026 putative lipoprotein YP_002415167.1 4730950 D 585056 CDS YP_002415168.1 218707649 7159332 4731585..4732322 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4732322 yjbG 7159332 yjbG Escherichia coli UMN026 hypothetical protein YP_002415168.1 4731585 D 585056 CDS YP_002415169.1 218707650 7159333 4732322..4734418 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative porin 4734418 yjbH 7159333 yjbH Escherichia coli UMN026 putative porin YP_002415169.1 4732322 D 585056 CDS YP_002415170.1 218707651 7159334 4734422..4734583 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4734583 7159334 ECUMN_4563 Escherichia coli UMN026 hypothetical protein YP_002415170.1 4734422 D 585056 CDS YP_002415171.1 218707652 7155474 complement(4734465..4734743) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4734743 7155474 ECUMN_4564 Escherichia coli UMN026 hypothetical protein YP_002415171.1 4734465 R 585056 CDS YP_002415172.1 218707653 7155475 4734957..4735367 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : putative membrane component; phosphate-starvation-inducible protein PsiE 4735367 yjbA 7155475 yjbA Escherichia coli UMN026 phosphate-starvation-inducible protein PsiE YP_002415172.1 4734957 D 585056 CDS YP_002415173.1 218707654 7159328 complement(4735461..4736351) 1 NC_011751.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4736351 malG 7159328 malG Escherichia coli UMN026 maltose transporter permease YP_002415173.1 4735461 R 585056 CDS YP_002415174.1 218707655 7157043 complement(4736366..4737910) 1 NC_011751.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4737910 malF 7157043 malF Escherichia coli UMN026 maltose transporter membrane protein YP_002415174.1 4736366 R 585056 CDS YP_002415175.1 218707656 7157042 complement(4738064..4739254) 1 NC_011751.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4739254 malE 7157042 malE Escherichia coli UMN026 maltose ABC transporter periplasmic protein YP_002415175.1 4738064 R 585056 CDS YP_002415176.1 218707657 7157041 4739619..4740734 1 NC_011751.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4740734 malK 7157041 malK Escherichia coli UMN026 maltose/maltodextrin transporter ATP-binding protein YP_002415176.1 4739619 D 585056 CDS YP_002415177.1 218707658 7157045 4740806..4742146 1 NC_011751.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4742146 lamB 7157045 lamB Escherichia coli UMN026 maltoporin YP_002415177.1 4740806 D 585056 CDS YP_002415178.1 218707659 7156934 4742296..4743216 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : putative transporter; maltose regulon periplasmic protein 4743216 malM 7156934 malM Escherichia coli UMN026 maltose regulon periplasmic protein YP_002415178.1 4742296 D 585056 CDS YP_002415179.1 218707660 7157046 4743445..4745025 1 NC_011751.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 4745025 yjbI 7157046 yjbI Escherichia coli UMN026 hypothetical protein YP_002415179.1 4743445 D 585056 CDS YP_002415180.1 218707661 7159335 4745248..4745745 1 NC_011751.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4745745 ubiC 7159335 ubiC Escherichia coli UMN026 chorismate pyruvate lyase YP_002415180.1 4745248 D 585056 CDS YP_002415181.1 218707662 7158154 4745758..4746630 1 NC_011751.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4746630 ubiA 7158154 ubiA Escherichia coli UMN026 4-hydroxybenzoate octaprenyltransferase YP_002415181.1 4745758 D 585056 CDS YP_002415182.1 218707663 7158152 complement(4746785..4749208) 1 NC_011751.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4749208 plsB 7158152 plsB Escherichia coli UMN026 glycerol-3-phosphate acyltransferase YP_002415182.1 4746785 R 585056 CDS YP_002415183.1 218707664 7157472 4749379..4749747 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme; diacylglycerol kinase 4749747 dgkA 7157472 dgkA Escherichia coli UMN026 diacylglycerol kinase YP_002415183.1 4749379 D 585056 CDS YP_002415184.1 218707665 7156148 4749857..4750465 1 NC_011751.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4750465 lexA 7156148 lexA Escherichia coli UMN026 LexA repressor YP_002415184.1 4749857 D 585056 CDS YP_002415185.1 218707666 7156949 4750484..4751863 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process; DNA-damage-inducible SOS response protein 4751863 dinF 7156949 dinF Escherichia coli UMN026 DNA-damage-inducible SOS response protein YP_002415185.1 4750484 D 585056 CDS YP_002415186.1 218707667 7156168 4751979..4752188 1 NC_011751.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4752188 yjbJ 7156168 yjbJ Escherichia coli UMN026 putative stress-response protein YP_002415186.1 4751979 D 585056 CDS YP_002415187.1 218707668 7159336 complement(4752230..4752745) 1 NC_011751.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4752745 zur 7159336 zur Escherichia coli UMN026 zinc uptake transcriptional repressor YP_002415187.1 4752230 R 585056 CDS YP_002415188.1 218707669 7159696 4753063..4754025 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4754025 7159696 ECUMN_4582 Escherichia coli UMN026 hypothetical protein YP_002415188.1 4753063 D 585056 CDS YP_002415189.1 218707670 7155476 4754388..4755425 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA -dihydrouridine synthase A 4755425 yjbN 7155476 yjbN Escherichia coli UMN026 tRNA -dihydrouridine synthase A YP_002415189.1 4754388 D 585056 CDS YP_002415190.1 218707671 7159337 4755349..4755801 1 NC_011751.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4755801 pspG 7159337 pspG Escherichia coli UMN026 phage shock protein G YP_002415190.1 4755349 D 585056 CDS YP_002415191.1 218707672 7159338 complement(4755967..4756950) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme; quinone oxidoreductase, NADPH-dependent 4756950 qor 7159338 qor Escherichia coli UMN026 quinone oxidoreductase, NADPH-dependent YP_002415191.1 4755967 R 585056 CDS YP_002415192.1 218707673 7157609 4757033..4758448 1 NC_011751.1 unwinds double stranded DNA; replicative DNA helicase 4758448 dnaB 7157609 dnaB Escherichia coli UMN026 replicative DNA helicase YP_002415192.1 4757033 D 585056 CDS YP_002415193.1 218707674 7156184 4758501..4759580 1 NC_011751.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4759580 alr 7156184 alr Escherichia coli UMN026 alanine racemase YP_002415193.1 4758501 D 585056 CDS YP_002415194.1 218707675 7155731 4759833..4761026 1 NC_011751.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4761026 tyrB 7155731 tyrB Escherichia coli UMN026 aromatic amino acid aminotransferase YP_002415194.1 4759833 D 585056 CDS YP_002415195.1 218707676 7158148 complement(4761248..4761790) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4761790 7158148 ECUMN_4590 Escherichia coli UMN026 hypothetical protein YP_002415195.1 4761248 R 585056 CDS YP_002415196.1 218707677 7155477 4762152..4762865 1 NC_011751.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4762865 aphA 7155477 aphA Escherichia coli UMN026 acid phosphatase/phosphotransferase YP_002415196.1 4762152 D 585056 CDS YP_002415197.1 218707678 7155750 4762976..4763392 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052; hypothetical protein 4763392 yjbQ 7155750 yjbQ Escherichia coli UMN026 hypothetical protein YP_002415197.1 4762976 D 585056 CDS YP_002415198.1 218707679 7159339 4763396..4763752 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4763752 yjbR 7159339 yjbR Escherichia coli UMN026 hypothetical protein YP_002415198.1 4763396 D 585056 CDS YP_002415199.1 218707680 7159340 complement(4763787..4766609) 1 NC_011751.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4766609 uvrA 7159340 uvrA Escherichia coli UMN026 excinuclease ABC subunit A YP_002415199.1 4763787 R 585056 CDS YP_002415200.1 218707681 7158198 4766864..4767400 1 NC_011751.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4767400 ssb 7158198 ssb Escherichia coli UMN026 single-stranded DNA-binding protein YP_002415200.1 4766864 D 585056 CDS YP_002415201.1 218707682 7157982 complement(4767499..4767780) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4767780 yjcB 7157982 yjcB Escherichia coli UMN026 hypothetical protein YP_002415201.1 4767499 R 585056 CDS YP_002415202.1 218707683 7159341 4768200..4769792 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative signal transduction protein 4769792 yjcC 7159341 yjcC Escherichia coli UMN026 putative signal transduction protein YP_002415202.1 4768200 D 585056 CDS YP_002415203.1 218707684 7159342 complement(4769798..4770121) 1 NC_011751.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4770121 soxS 7159342 soxS Escherichia coli UMN026 DNA-binding transcriptional regulator SoxS YP_002415203.1 4769798 R 585056 CDS YP_002415204.1 218707685 7157954 4770207..4770671 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator; DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4770671 soxR 7157954 soxR Escherichia coli UMN026 DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing YP_002415204.1 4770207 D 585056 CDS YP_002415205.1 218707686 7157857 4771395..4772744 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative permease 4772744 yjcD 7157857 yjcD Escherichia coli UMN026 putative permease YP_002415205.1 4771395 D 585056 CDS YP_002415206.1 218707687 7159343 4772895..4774544 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : putative transporter; putative cation/proton antiporter 4774544 yjcE 7159343 yjcE Escherichia coli UMN026 putative cation/proton antiporter YP_002415206.1 4772895 D 585056 CDS YP_002415207.1 218707688 7159344 complement(4774698..4775990) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4775990 yjcF 7159344 yjcF Escherichia coli UMN026 hypothetical protein YP_002415207.1 4774698 R 585056 CDS YP_002415208.1 218707689 7159345 complement(4776168..4777817) 1 NC_011751.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4777817 actP 7159345 actP Escherichia coli UMN026 acetate permease YP_002415208.1 4776168 R 585056 CDS YP_002415209.1 218707690 7155694 complement(4777814..4778128) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14563880; Product type pm : putative membrane component; hypothetical protein 4778128 yjcH 7155694 yjcH Escherichia coli UMN026 hypothetical protein YP_002415209.1 4777814 R 585056 CDS YP_002415210.1 218707691 7159346 complement(4778601..4780559) 1 NC_011751.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4780559 acs 7159346 acs Escherichia coli UMN026 acetyl-CoA synthetase YP_002415210.1 4778601 R 585056 CDS YP_002415211.1 218707692 7155693 4780951..4782387 1 NC_011751.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4782387 nrfA 7155693 nrfA Escherichia coli UMN026 cytochrome c552 YP_002415211.1 4780951 D 585056 CDS YP_002415212.1 218707693 7157307 4782432..4782998 1 NC_011751.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4782998 nrfB 7157307 nrfB Escherichia coli UMN026 cytochrome c nitrite reductase pentaheme subunit YP_002415212.1 4782432 D 585056 CDS YP_002415213.1 218707694 7157308 4782995..4783666 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94335626, 8057835; Product type c : carrier; formate-dependent nitrite reductase, 4Fe4S subunit 4783666 nrfC 7157308 nrfC Escherichia coli UMN026 formate-dependent nitrite reductase, 4Fe4S subunit YP_002415213.1 4782995 D 585056 CDS YP_002415214.1 218707695 7157309 4783663..4784619 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 8057835; Product type e : enzyme; formate-dependent nitrite reductase, membrane subunit 4784619 nrfD 7157309 nrfD Escherichia coli UMN026 formate-dependent nitrite reductase, membrane subunit YP_002415214.1 4783663 D 585056 CDS YP_002415215.1 218707696 7157310 4784699..4786357 1 NC_011751.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4786357 nrfE 7157310 nrfE Escherichia coli UMN026 heme lyase subunit NrfE YP_002415215.1 4784699 D 585056 CDS YP_002415216.1 218707697 7157311 4786350..4786733 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor; formate-dependent nitrite reductase complex subunit NrfF 4786733 nrfF 7157311 nrfF Escherichia coli UMN026 formate-dependent nitrite reductase complex subunit NrfF YP_002415216.1 4786350 D 585056 CDS YP_002415217.1 218707698 7157312 4786730..4787326 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor; formate-dependent nitrite reductase complex subunit NrfG 4787326 nrfG 7157312 nrfG Escherichia coli UMN026 formate-dependent nitrite reductase complex subunit NrfG YP_002415217.1 4786730 D 585056 CDS YP_002415218.1 218707699 7157313 4787668..4788981 1 NC_011751.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4788981 gltP 7157313 gltP Escherichia coli UMN026 glutamate/aspartate:proton symporter YP_002415218.1 4787668 D 585056 CDS YP_002415219.1 218707700 7156580 complement(4789286..4789975) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4789975 yjcO 7156580 yjcO Escherichia coli UMN026 hypothetical protein YP_002415219.1 4789286 R 585056 CDS YP_002415220.1 218707701 7159347 complement(4790069..4792216) 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-H, selenopolypeptide subunit 4792216 fdhF 7159347 fdhF Escherichia coli UMN026 formate dehydrogenase-H, selenopolypeptide subunit YP_002415220.1 4790069 R 585056 CDS YP_002415221.1 218707702 7156315 complement(4792414..4793880) 1 NC_011751.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP 4793880 yjcP 7156315 yjcP Escherichia coli UMN026 putative outer membrane efflux protein MdtP YP_002415221.1 4792414 R 585056 CDS YP_002415222.1 218707703 7159348 complement(4793877..4795928) 1 NC_011751.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4795928 yjcQ 7159348 yjcQ Escherichia coli UMN026 multidrug efflux system protein MdtO YP_002415222.1 4793877 R 585056 CDS YP_002415223.1 218707704 7159349 complement(4795928..4796959) 1 NC_011751.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4796959 yjcR 7159349 yjcR Escherichia coli UMN026 multidrug resistance protein MdtN YP_002415223.1 4795928 R 585056 CDS YP_002415224.1 218707705 7159350 complement(4797462..4799447) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : putative enzyme; putative alkyl sulfatase 4799447 yjcS 7159350 yjcS Escherichia coli UMN026 putative alkyl sulfatase YP_002415224.1 4797462 R 585056 CDS YP_002415225.1 218707706 7159351 4799700..4800017 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ribose-5-phosphate isomerase B 4800017 7159351 ECUMN_4621 Escherichia coli UMN026 putative ribose-5-phosphate isomerase B YP_002415225.1 4799700 D 585056 CDS YP_002415226.1 218707707 7155478 4800086..4800415 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4800415 yjdP 7155478 yjdP Escherichia coli UMN026 hypothetical protein YP_002415226.1 4800086 D 585056 CDS YP_002415227.1 218707708 7159362 complement(4800450..4801208) 1 NC_011751.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 4801208 phnP 7159362 phnP Escherichia coli UMN026 carbon-phosphorus lyase complex accessory protein YP_002415227.1 4800450 R 585056 CDS YP_002415228.1 218707709 7157454 complement(4801210..4801644) 1 NC_011751.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase 4801644 phnO 7157454 phnO Escherichia coli UMN026 aminoalkylphosphonic acid N-acetyltransferase YP_002415228.1 4801210 R 585056 CDS YP_002415229.1 218707710 7157453 complement(4801631..4802188) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700258, 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; ribose 1,5-bisphosphokinase 4802188 phnN 7157453 phnN Escherichia coli UMN026 ribose 1,5-bisphosphokinase YP_002415229.1 4801631 R 585056 CDS YP_002415230.1 218707711 7157452 complement(4802188..4803324) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4803324 phnM 7157452 phnM Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415230.1 4802188 R 585056 CDS YP_002415231.1 218707712 7157451 complement(4803321..4804001) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4804001 phnL 7157451 phnL Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415231.1 4803321 R 585056 CDS YP_002415232.1 218707713 7157450 complement(4804112..4804870) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; phosphonate C-P lyase system protein PhnK 4804870 phnK 7157450 phnK Escherichia coli UMN026 phosphonate C-P lyase system protein PhnK YP_002415232.1 4804112 R 585056 CDS YP_002415233.1 218707714 7157449 complement(4804867..4805712) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4805712 phnJ 7157449 phnJ Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415233.1 4804867 R 585056 CDS YP_002415234.1 218707715 7157448 complement(4805705..4806769) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4806769 phnI 7157448 phnI Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415234.1 4805705 R 585056 CDS YP_002415235.1 218707716 7157447 complement(4806769..4807353) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4807353 phnH 7157447 phnH Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415235.1 4806769 R 585056 CDS YP_002415236.1 218707717 7157446 complement(4807350..4807802) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme; carbon-phosphorus lyase complex subunit 4807802 phnG 7157446 phnG Escherichia coli UMN026 carbon-phosphorus lyase complex subunit YP_002415236.1 4807350 R 585056 CDS YP_002415237.1 218707718 7157445 complement(4807803..4808528) 1 NC_011751.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 4808528 phnF 7157445 phnF Escherichia coli UMN026 phosphonate metabolism transcriptional regulator PhnF YP_002415237.1 4807803 R 585056 CDS YP_002415238.1 218707719 7157444 complement(4808549..4809328) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; phosphonates transport system, permease protein 4809328 phnE 7157444 phnE Escherichia coli UMN026 phosphonates transport system, permease protein YP_002415238.1 4808549 R 585056 CDS YP_002415239.1 218707720 7157443 complement(4809389..4810405) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter; phosphonate/organophosphate ester ABC transporter periplasmic binding protein 4810405 phnD 7157443 phnD Escherichia coli UMN026 phosphonate/organophosphate ester ABC transporter periplasmic binding protein YP_002415239.1 4809389 R 585056 CDS YP_002415240.1 218707721 7157442 complement(4810430..4811218) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter; phosphonate/organophosphate ester transporter subunit 4811218 phnC 7157442 phnC Escherichia coli UMN026 phosphonate/organophosphate ester transporter subunit YP_002415240.1 4810430 R 585056 CDS YP_002415241.1 218707722 7157441 complement(4811351..4811794) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein 4811794 phnB 7157441 phnB Escherichia coli UMN026 hypothetical protein YP_002415241.1 4811351 R 585056 CDS YP_002415242.1 218707723 7157440 complement(4811954..4812289) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein 4812289 phnA 7157440 phnA Escherichia coli UMN026 hypothetical protein YP_002415242.1 4811954 R 585056 CDS YP_002415243.1 218707724 7157439 4812691..4814919 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4814919 yjdA 7157439 yjdA Escherichia coli UMN026 hypothetical protein YP_002415243.1 4812691 D 585056 CDS YP_002415244.1 218707725 7159353 4814916..4815794 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4815794 yjcZ 7159353 yjcZ Escherichia coli UMN026 hypothetical protein YP_002415244.1 4814916 D 585056 CDS YP_002415245.1 218707726 7159352 4816058..4817560 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter; proline/glycine betaine transporter 4817560 proP 7159352 proP Escherichia coli UMN026 proline/glycine betaine transporter YP_002415245.1 4816058 D 585056 CDS YP_002415246.1 218707727 7157533 complement(4817737..4818828) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; sensor protein BasS/PmrB 4818828 basS 7157533 basS Escherichia coli UMN026 sensor protein BasS/PmrB YP_002415246.1 4817737 R 585056 CDS YP_002415247.1 218707728 7155853 complement(4818838..4819506) 1 NC_011751.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4819506 basR 7155853 basR Escherichia coli UMN026 DNA-binding transcriptional regulator BasR YP_002415247.1 4818838 R 585056 CDS YP_002415248.1 218707729 7155852 complement(4819503..4821146) 1 NC_011751.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein 4821146 eptA 7155852 eptA Escherichia coli UMN026 putative cell division protein YP_002415248.1 4819503 R 585056 CDS YP_002415249.1 218707730 7156265 complement(4821250..4822587) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12867448; Product type t : transporter; arginine:agmatin antiporter 4822587 adiC 7156265 adiC Escherichia coli UMN026 arginine:agmatin antiporter YP_002415249.1 4821250 R 585056 CDS YP_002415250.1 218707731 7155701 complement(4822724..4823485) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator; DNA-binding transcriptional activator 4823485 adiY 7155701 adiY Escherichia coli UMN026 DNA-binding transcriptional activator YP_002415250.1 4822724 R 585056 CDS YP_002415251.1 218707732 7155702 complement(4823821..4826091) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93186686, 2830169, 4204273, 8383109; Product type e : enzyme; biodegradative arginine decarboxylase 4826091 adiA 7155702 adiA Escherichia coli UMN026 biodegradative arginine decarboxylase YP_002415251.1 4823821 R 585056 CDS YP_002415252.1 218707733 7155700 complement(4826287..4827195) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90060832, 9108148, 1445207, 2684786, 2830169; Product type r : regulator; DNA-binding transcriptional regulator MelR 4827195 melR 7155700 melR Escherichia coli UMN026 DNA-binding transcriptional regulator MelR YP_002415252.1 4826287 R 585056 CDS YP_002415253.1 218707734 7157092 4827478..4828833 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174747, 88162811, 90248411, 2831880, 3031590, 6329200; Product type e : enzyme; alpha-galactosidase 4828833 melA 7157092 melA Escherichia coli UMN026 alpha-galactosidase YP_002415253.1 4827478 D 585056 CDS YP_002415254.1 218707735 7157090 4828948..4830357 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14757226, 90241878, 92297631, 93155159, 1730719, 1872836, 6323466, 8672452; Product type t : transporter; melibiose:sodium symporter 4830357 melB 7157090 melB Escherichia coli UMN026 melibiose:sodium symporter YP_002415254.1 4828948 D 585056 CDS YP_002415255.1 218707736 7157091 complement(4830496..4831125) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4831125 yjdF 7157091 yjdF Escherichia coli UMN026 hypothetical protein YP_002415255.1 4830496 R 585056 CDS YP_002415256.1 218707737 7159356 complement(4831248..4832894) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme; anaerobic class I fumarate hydratase 4832894 fumB 7159356 fumB Escherichia coli UMN026 anaerobic class I fumarate hydratase YP_002415256.1 4831248 R 585056 CDS YP_002415257.1 218707738 7156477 complement(4832972..4834312) 1 NC_011751.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4834312 dcuB 7156477 dcuB Escherichia coli UMN026 anaerobic C4-dicarboxylate transporter YP_002415257.1 4832972 R 585056 CDS YP_002415258.1 218707739 7156119 complement(4834883..4835602) 1 NC_011751.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4835602 dcuR 7156119 dcuR Escherichia coli UMN026 DNA-binding transcriptional activator DcuR YP_002415258.1 4834883 R 585056 CDS YP_002415259.1 218707740 7156122 complement(4835599..4837230) 1 NC_011751.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4837230 dcuS 7156122 dcuS Escherichia coli UMN026 sensory histidine kinase DcuS YP_002415259.1 4835599 R 585056 CDS YP_002415260.1 218707741 7156123 4837411..4837641 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4837641 yjdI 7156123 yjdI Escherichia coli UMN026 hypothetical protein YP_002415260.1 4837411 D 585056 CDS YP_002415261.1 218707742 7159357 4837653..4837925 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acyltransferase 4837925 yjdJ 7159357 yjdJ Escherichia coli UMN026 putative acyltransferase YP_002415261.1 4837653 D 585056 CDS YP_002415262.1 218707743 7159358 4838154..4838450 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4838450 yjdK 7159358 yjdK Escherichia coli UMN026 hypothetical protein YP_002415262.1 4838154 D 585056 CDS YP_002415263.1 218707744 7159359 4838478..4838651 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4838651 yjdO 7159359 yjdO Escherichia coli UMN026 hypothetical protein YP_002415263.1 4838478 D 585056 CDS YP_002415264.1 218707745 7159361 complement(4838769..4840286) 1 NC_011751.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 4840286 lysU 7159361 lysU Escherichia coli UMN026 lysyl-tRNA synthetase YP_002415264.1 4838769 R 585056 CDS YP_002415265.1 218707746 7157034 complement(4840523..4841980) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4841980 yjdL 7157034 yjdL Escherichia coli UMN026 putative transporter YP_002415265.1 4840523 R 585056 CDS YP_002415266.1 218707747 7159360 complement(4842039..4844186) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme; lysine decarboxylase 1 4844186 cadA 7159360 cadA Escherichia coli UMN026 lysine decarboxylase 1 YP_002415266.1 4842039 R 585056 CDS YP_002415267.1 218707748 7155907 complement(4844266..4845600) 1 NC_011751.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 4845600 cadB 7155907 cadB Escherichia coli UMN026 lysine/cadaverine antiporter YP_002415267.1 4844266 R 585056 CDS YP_002415268.1 218707749 7155908 complement(4845966..4847504) 1 NC_011751.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 4847504 cadC 7155908 cadC Escherichia coli UMN026 DNA-binding transcriptional activator CadC YP_002415268.1 4845966 R 585056 CDS YP_002415269.1 218707750 7155909 4847740..4848009 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4848009 7155909 ECUMN_4668 Escherichia coli UMN026 hypothetical protein YP_002415269.1 4847740 D 585056 CDS YP_002415270.1 218707751 7159355 complement(4848905..4850602) 1 NC_011751.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4850602 dipZ 7159355 dipZ Escherichia coli UMN026 thiol:disulfide interchange protein YP_002415270.1 4848905 R 585056 CDS YP_002415271.1 218707752 7156171 complement(4850578..4850916) 1 NC_011751.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4850916 cutA 7156171 cutA Escherichia coli UMN026 divalent-cation tolerance protein CutA YP_002415271.1 4850578 R 585056 CDS YP_002415272.1 218707753 7156056 complement(4851031..4852332) 1 NC_011751.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4852332 dcuA 7156056 dcuA Escherichia coli UMN026 anaerobic C4-dicarboxylate transporter YP_002415272.1 4851031 R 585056 CDS YP_002415273.1 218707754 7156118 complement(4852450..4853886) 1 NC_011751.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4853886 aspA 7156118 aspA Escherichia coli UMN026 aspartate ammonia-lyase YP_002415273.1 4852450 R 585056 CDS YP_002415274.1 218707755 7155817 4854223..4854699 1 NC_011751.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 4854699 fxsA 7155817 fxsA Escherichia coli UMN026 FxsA YP_002415274.1 4854223 D 585056 CDS YP_002415275.1 218707756 7156481 complement(4854715..4855971) 1 NC_011751.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4855971 yjeH 7156481 yjeH Escherichia coli UMN026 inner membrane protein YjeH YP_002415275.1 4854715 R 585056 CDS YP_002415276.1 218707757 7159365 4856247..4856540 1 NC_011751.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4856540 groES 7159365 groES Escherichia coli UMN026 co-chaperonin GroES YP_002415276.1 4856247 D 585056 CDS YP_002415277.1 218707758 7156612 4856584..4858230 1 NC_011751.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4858230 groEL 7156612 groEL Escherichia coli UMN026 chaperonin GroEL YP_002415277.1 4856584 D 585056 CDS YP_002415278.1 218707759 7156611 4858368..4858721 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4858721 yjeI 7156611 yjeI Escherichia coli UMN026 hypothetical protein YP_002415278.1 4858368 D 585056 CDS YP_002415279.1 218707760 7159366 complement(4858771..4859640) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4859640 yjeJ 7159366 yjeJ Escherichia coli UMN026 hypothetical protein YP_002415279.1 4858771 R 585056 CDS YP_002415280.1 218707761 7159367 complement(4859875..4860903) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : putative enzyme; putative lysine aminomutase 4860903 yjeK 7159367 yjeK Escherichia coli UMN026 putative lysine aminomutase YP_002415280.1 4859875 R 585056 CDS YP_002415281.1 218707762 7159368 4860945..4861511 1 NC_011751.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4861511 efp 7159368 efp Escherichia coli UMN026 elongation factor P YP_002415281.1 4860945 D 585056 CDS YP_002415282.1 218707763 7156231 complement(4861783..4862034) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4862034 7156231 ECUMN_4683 Escherichia coli UMN026 hypothetical protein YP_002415282.1 4861783 R 585056 CDS YP_002415283.1 218707764 7155480 4862120..4862437 1 NC_011751.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4862437 sugE 7155480 sugE Escherichia coli UMN026 quaternary ammonium compound-resistance protein SugE YP_002415283.1 4862120 D 585056 CDS YP_002415284.1 218707765 7158009 complement(4862434..4862967) 1 NC_011751.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4862967 blc 7158009 blc Escherichia coli UMN026 outer membrane lipoprotein Blc YP_002415284.1 4862434 R 585056 CDS YP_002415285.1 218707766 7155887 complement(4863056..4864189) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme; beta-lactamase 4864189 ampC 7155887 ampC Escherichia coli UMN026 beta-lactamase YP_002415285.1 4863056 R 585056 CDS YP_002415286.1 218707767 7155737 complement(4864252..4864611) 1 NC_011751.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4864611 frdD 7155737 frdD Escherichia coli UMN026 fumarate reductase subunit D YP_002415286.1 4864252 R 585056 CDS YP_002415287.1 218707768 7156437 complement(4864622..4865017) 1 NC_011751.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4865017 frdC 7156437 frdC Escherichia coli UMN026 fumarate reductase subunit C YP_002415287.1 4864622 R 585056 CDS YP_002415288.1 218707769 7156436 complement(4865028..4865762) 1 NC_011751.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4865762 frdB 7156436 frdB Escherichia coli UMN026 fumarate reductase iron-sulfur subunit YP_002415288.1 4865028 R 585056 CDS YP_002415289.1 218707770 7156435 complement(4865755..4867563) 1 NC_011751.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4867563 frdA 7156435 frdA Escherichia coli UMN026 fumarate reductase flavoprotein subunit YP_002415289.1 4865755 R 585056 CDS YP_002415290.1 218707771 7156434 4867888..4868865 1 NC_011751.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4868865 poxA 7156434 poxA Escherichia coli UMN026 lysyl-tRNA synthetase YP_002415290.1 4867888 D 585056 CDS YP_002415291.1 218707772 7157495 4869084..4870586 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter 4870586 yjeM 7157495 yjeM Escherichia coli UMN026 putative transporter YP_002415291.1 4869084 D 585056 CDS YP_002415292.1 218707773 7159369 complement(4870737..4874060) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; hypothetical protein 4874060 yjeP 7159369 yjeP Escherichia coli UMN026 hypothetical protein YP_002415292.1 4870737 R 585056 CDS YP_002415293.1 218707774 7159370 complement(4874082..4875050) 1 NC_011751.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4875050 psd 7159370 psd Escherichia coli UMN026 phosphatidylserine decarboxylase YP_002415293.1 4874082 R 585056 CDS YP_002415294.1 218707775 7157548 complement(4875147..4876199) 1 NC_011751.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4876199 rsgA 7157548 rsgA Escherichia coli UMN026 ribosome-associated GTPase YP_002415294.1 4875147 R 585056 CDS YP_002415295.1 218707776 7157796 4876294..4876839 1 NC_011751.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4876839 orn 7157796 orn Escherichia coli UMN026 oligoribonuclease YP_002415295.1 4876294 D 585056 CDS YP_002415296.1 218707777 7155610 complement(4877739..4878878) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier; putative Fe-S electron transport protein 4878878 yjeS 7155610 yjeS Escherichia coli UMN026 putative Fe-S electron transport protein YP_002415296.1 4877739 R 585056 CDS YP_002415297.1 218707778 7159371 4878877..4880424 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 4880424 yjeF 7159371 yjeF Escherichia coli UMN026 hypothetical protein YP_002415297.1 4878877 D 585056 CDS YP_002415298.1 218707779 7159364 4880396..4880857 1 NC_011751.1 possibly involved in cell wall synthesis; putative ATPase 4880857 yjeE 7159364 yjeE Escherichia coli UMN026 putative ATPase YP_002415298.1 4880396 D 585056 CDS YP_002415299.1 218707780 7159363 4880876..4882213 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase II 4882213 amiB 7159363 amiB Escherichia coli UMN026 N-acetylmuramoyl-l-alanine amidase II YP_002415299.1 4880876 D 585056 CDS YP_002415300.1 218707781 7155734 4882223..4884070 1 NC_011751.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4884070 mutL 7155734 mutL Escherichia coli UMN026 DNA mismatch repair protein YP_002415300.1 4882223 D 585056 CDS YP_002415301.1 218707782 7157212 4884063..4885013 1 NC_011751.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4885013 miaA 7157212 miaA Escherichia coli UMN026 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002415301.1 4884063 D 585056 CDS YP_002415302.1 218707783 7157128 4885099..4885407 1 NC_011751.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4885407 hfq 7157128 hfq Escherichia coli UMN026 RNA-binding protein Hfq YP_002415302.1 4885099 D 585056 CDS YP_002415303.1 218707784 7156667 4885484..4886764 1 NC_011751.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4886764 hflX 7156667 hflX Escherichia coli UMN026 putative GTPase HflX YP_002415303.1 4885484 D 585056 CDS YP_002415304.1 218707785 7156666 4886850..4888109 1 NC_011751.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4888109 hflK 7156666 hflK Escherichia coli UMN026 FtsH protease regulator HflK YP_002415304.1 4886850 D 585056 CDS YP_002415305.1 218707786 7156665 4888112..4889116 1 NC_011751.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4889116 hflC 7156665 hflC Escherichia coli UMN026 FtsH protease regulator HflC YP_002415305.1 4888112 D 585056 CDS YP_002415306.1 218707787 7156663 4889198..4889395 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4889395 yjeT 7156663 yjeT Escherichia coli UMN026 hypothetical protein YP_002415306.1 4889198 D 585056 CDS YP_002415307.1 218707788 7159372 4889499..4890797 1 NC_011751.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4890797 purA 7159372 purA Escherichia coli UMN026 adenylosuccinate synthetase YP_002415307.1 4889499 D 585056 CDS YP_002415308.1 218707789 7157572 4891002..4891427 1 NC_011751.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4891427 nsrR 7157572 nsrR Escherichia coli UMN026 transcriptional repressor NsrR YP_002415308.1 4891002 D 585056 CDS YP_002415309.1 218707790 7157314 4891466..4893907 1 NC_011751.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4893907 rnr 7157314 rnr Escherichia coli UMN026 exoribonuclease R YP_002415309.1 4891466 D 585056 CDS YP_002415310.1 218707791 7157718 4893998..4894729 1 NC_011751.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4894729 rlmB 7157718 rlmB Escherichia coli UMN026 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002415310.1 4893998 D 585056 CDS YP_002415311.1 218707792 7157696 4894856..4895257 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4895257 yjfI 7157696 yjfI Escherichia coli UMN026 hypothetical protein YP_002415311.1 4894856 D 585056 CDS YP_002415312.1 218707793 7159375 4895276..4895974 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator effector protein 4895974 yjfJ 7159375 yjfJ Escherichia coli UMN026 putative transcriptional regulator effector protein YP_002415312.1 4895276 D 585056 CDS YP_002415313.1 218707794 7159376 4896025..4896684 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4896684 yjfK 7159376 yjfK Escherichia coli UMN026 hypothetical protein YP_002415313.1 4896025 D 585056 CDS YP_002415314.1 218707795 7159377 4896702..4897100 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4897100 yjfL 7159377 yjfL Escherichia coli UMN026 hypothetical protein YP_002415314.1 4896702 D 585056 CDS YP_002415315.1 218707796 7159378 4897110..4897748 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4897748 yjfM 7159378 yjfM Escherichia coli UMN026 hypothetical protein YP_002415315.1 4897110 D 585056 CDS YP_002415316.1 218707797 7159379 4897751..4898914 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative synthetase/amidase 4898914 yjfC 7159379 yjfC Escherichia coli UMN026 putative synthetase/amidase YP_002415316.1 4897751 D 585056 CDS YP_002415317.1 218707798 7159373 4898998..4900623 1 NC_011751.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4900623 aidB 7159373 aidB Escherichia coli UMN026 isovaleryl CoA dehydrogenase YP_002415317.1 4898998 D 585056 CDS YP_002415318.1 218707799 7155719 complement(4900740..4901015) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4901015 yjfN 7155719 yjfN Escherichia coli UMN026 hypothetical protein YP_002415318.1 4900740 R 585056 CDS YP_002415319.1 218707800 7159380 complement(4901164..4901493) 1 NC_011751.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A 4901493 yjfO 7159380 yjfO Escherichia coli UMN026 putative biofilm stress and motility protein A YP_002415319.1 4901164 R 585056 CDS YP_002415320.1 218707801 7159381 4901675..4902424 1 NC_011751.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4902424 yjfP 7159381 yjfP Escherichia coli UMN026 esterase YP_002415320.1 4901675 D 585056 CDS YP_002415321.1 218707802 7159382 complement(4902421..4903176) 1 NC_011751.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4903176 ulaR 7159382 ulaR Escherichia coli UMN026 transcriptional repressor UlaR YP_002415321.1 4902421 R 585056 CDS YP_002415322.1 218707803 7158185 complement(4903284..4904348) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : putative enzyme; putative L-ascorbate 6-phosphate lactonase 4904348 ulaG 7158185 ulaG Escherichia coli UMN026 putative L-ascorbate 6-phosphate lactonase YP_002415322.1 4903284 R 585056 CDS YP_002415323.1 218707804 7158184 4904703..4906100 1 NC_011751.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4906100 ulaA 7158184 ulaA Escherichia coli UMN026 PTS system ascorbate-specific transporter subunit IIC YP_002415323.1 4904703 D 585056 CDS YP_002415324.1 218707805 7158178 4906116..4906421 1 NC_011751.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4906421 ulaB 7158178 ulaB Escherichia coli UMN026 PTS system L-ascorbate-specific transporter subunit IIB YP_002415324.1 4906116 D 585056 CDS YP_002415325.1 218707806 7158179 4906431..4906895 1 NC_011751.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4906895 ulaC 7158179 ulaC Escherichia coli UMN026 PTS system L-ascorbate-specific transporter subunit IIA YP_002415325.1 4906431 D 585056 CDS YP_002415326.1 218707807 7158180 4906909..4907559 1 NC_011751.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4907559 ulaD 7158180 ulaD Escherichia coli UMN026 3-keto-L-gulonate-6-phosphate decarboxylase YP_002415326.1 4906909 D 585056 CDS YP_002415327.1 218707808 7158181 4907569..4908423 1 NC_011751.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4908423 ulaE 7158181 ulaE Escherichia coli UMN026 L-xylulose 5-phosphate 3-epimerase YP_002415327.1 4907569 D 585056 CDS YP_002415328.1 218707809 7158182 4908423..4909109 1 NC_011751.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4909109 sgaE 7158182 sgaE Escherichia coli UMN026 L-ribulose-5-phosphate 4-epimerase YP_002415328.1 4908423 D 585056 CDS YP_002415329.1 218707810 7158183 complement(4909239..4909514) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4909514 yjfY 7158183 yjfY Escherichia coli UMN026 hypothetical protein YP_002415329.1 4909239 R 585056 CDS YP_002415330.1 218707811 7159383 4909841..4910236 1 NC_011751.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4910236 rpsF 7159383 rpsF Escherichia coli UMN026 30S ribosomal protein S6 YP_002415330.1 4909841 D 585056 CDS YP_002415331.1 218707812 7157772 4910243..4910557 1 NC_011751.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4910557 priB 7157772 priB Escherichia coli UMN026 primosomal replication protein N YP_002415331.1 4910243 D 585056 CDS YP_002415332.1 218707813 7157523 4910562..4910789 1 NC_011751.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4910789 rpsR 7157523 rpsR Escherichia coli UMN026 30S ribosomal protein S18 YP_002415332.1 4910562 D 585056 CDS YP_002415333.1 218707814 7157784 4910831..4911280 1 NC_011751.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4911280 rplI 7157784 rplI Escherichia coli UMN026 50S ribosomal protein L9 YP_002415333.1 4910831 D 585056 CDS YP_002415334.1 218707815 7157731 complement(4911351..4912145) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4912145 yjfZ 7157731 yjfZ Escherichia coli UMN026 hypothetical protein YP_002415334.1 4911351 R 585056 CDS YP_002415335.1 218707816 7159666 4913086..4913232 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4913232 7159666 ECUMN_4739 Escherichia coli UMN026 hypothetical protein YP_002415335.1 4913086 D 585056 CDS YP_002415336.1 218707817 7155481 4913210..4914406 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative transposase 4914406 ydcM 7155481 ydcM Escherichia coli UMN026 putative transposase YP_002415336.1 4913210 D 585056 CDS YP_002415337.1 218707818 7158611 complement(4914553..4915191) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : putative structure; putative cell envelope opacity-associated protein 4915191 ytfB 7158611 ytfB Escherichia coli UMN026 putative cell envelope opacity-associated protein YP_002415337.1 4914553 R 585056 CDS YP_002415338.1 218707819 7159667 4915409..4916029 1 NC_011751.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4916029 fklB 7159667 fklB Escherichia coli UMN026 peptidyl-prolyl cis-trans isomerase YP_002415338.1 4915409 D 585056 CDS YP_002415339.1 218707820 7156372 4916338..4917741 1 NC_011751.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4917741 cycA 7156372 cycA Escherichia coli UMN026 D-alanine/D-serine/glycine permease YP_002415339.1 4916338 D 585056 CDS YP_002415340.1 218707821 7156064 4917875..4919038 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4919038 7156064 ECUMN_4744 Escherichia coli UMN026 hypothetical protein YP_002415340.1 4917875 D 585056 CDS YP_002415341.1 218707822 7155482 4919072..4920556 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4920556 7155482 ECUMN_4745 Escherichia coli UMN026 hypothetical protein YP_002415341.1 4919072 D 585056 CDS YP_002415342.1 218707823 7155483 complement(4920601..4921263) 1 NC_011751.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4921263 ytfE 7155483 ytfE Escherichia coli UMN026 iron-sulfur cluster repair di-iron protein YP_002415342.1 4920601 R 585056 CDS YP_002415343.1 218707824 7159668 complement(4921371..4922345) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4922345 ytfF 7159668 ytfF Escherichia coli UMN026 hypothetical protein YP_002415343.1 4921371 R 585056 CDS YP_002415344.1 218707825 7159669 complement(4922445..4923305) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme; NAD(P)H:quinone oxidoreductase 4923305 ytfG 7159669 ytfG Escherichia coli UMN026 NAD(P)H:quinone oxidoreductase YP_002415344.1 4922445 R 585056 CDS YP_002415345.1 218707826 7159670 4923393..4923773 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : putative regulator; putative transcriptional regulator 4923773 ytfH 7159670 ytfH Escherichia coli UMN026 putative transcriptional regulator YP_002415345.1 4923393 D 585056 CDS YP_002415346.1 218707827 7159671 complement(4923902..4925845) 1 NC_011751.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4925845 cpdB 7159671 cpdB Escherichia coli UMN026 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_002415346.1 4923902 R 585056 CDS YP_002415347.1 218707828 7156001 4926035..4926775 1 NC_011751.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4926775 cysQ 7156001 cysQ Escherichia coli UMN026 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_002415347.1 4926035 D 585056 CDS YP_002415348.1 218707829 7156091 complement(4926765..4927322) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : putative regulator; putative transcriptional regulator 4927322 ytfJ 7156091 ytfJ Escherichia coli UMN026 putative transcriptional regulator YP_002415348.1 4926765 R 585056 CDS YP_002415349.1 218707830 7159672 4927647..4927853 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4927853 ytfK 7159672 ytfK Escherichia coli UMN026 hypothetical protein YP_002415349.1 4927647 D 585056 CDS YP_002415350.1 218707831 7159673 complement(4927914..4929257) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4929257 ytfL 7159673 ytfL Escherichia coli UMN026 hypothetical protein YP_002415350.1 4927914 R 585056 CDS YP_002415351.1 218707832 7159674 complement(4929580..4930218) 1 NC_011751.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4930218 msrA 7159674 msrA Escherichia coli UMN026 methionine sulfoxide reductase A YP_002415351.1 4929580 R 585056 CDS YP_002415352.1 218707833 7157187 4930424..4932157 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4932157 ytfM 7157187 ytfM Escherichia coli UMN026 hypothetical protein YP_002415352.1 4930424 D 585056 CDS YP_002415353.1 218707834 7159675 4932154..4935933 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4935933 ytfN 7159675 ytfN Escherichia coli UMN026 hypothetical protein YP_002415353.1 4932154 D 585056 CDS YP_002415354.1 218707835 7159676 4935936..4936277 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4936277 ytfP 7159676 ytfP Escherichia coli UMN026 hypothetical protein YP_002415354.1 4935936 D 585056 CDS YP_002415355.1 218707836 7159677 complement(4936657..4937187) 1 NC_011751.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4937187 ppa 7159677 ppa Escherichia coli UMN026 inorganic pyrophosphatase YP_002415355.1 4936657 R 585056 CDS YP_002415356.1 218707837 7157497 4937497..4938453 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter; putative sugar ABC transporter periplasmic-binding protein 4938453 ytfQ 7157497 ytfQ Escherichia coli UMN026 putative sugar ABC transporter periplasmic-binding protein YP_002415356.1 4937497 D 585056 CDS YP_002415357.1 218707838 7159678 4938763..4940265 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter ATP-binding protein 4940265 ytfR 7159678 ytfR Escherichia coli UMN026 putative sugar ABC transporter ATP-binding protein YP_002415357.1 4938763 D 585056 CDS YP_002415358.1 218707839 7159679 4940279..4941301 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sugar ABC transporter membrane protein 4941301 ytfT 7159679 ytfT Escherichia coli UMN026 putative sugar ABC transporter membrane protein YP_002415358.1 4940279 D 585056 CDS YP_002415359.1 218707840 7159680 4941288..4942283 1 NC_011751.1 membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease protein YjfF 4942283 yjfF 7159680 yjfF Escherichia coli UMN026 inner membrane ABC transporter permease protein YjfF YP_002415359.1 4941288 D 585056 CDS YP_002415360.1 218707841 7159374 complement(4942316..4943314) 1 NC_011751.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4943314 fbp 7159374 fbp Escherichia coli UMN026 fructose-1,6-bisphosphatase YP_002415360.1 4942316 R 585056 CDS YP_002415361.1 218707842 7156311 4943490..4944863 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4944863 mpl 7156311 mpl Escherichia coli UMN026 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002415361.1 4943490 D 585056 CDS YP_002415362.1 218707843 7157167 complement(4945014..4945565) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4945565 yjgA 7157167 yjgA Escherichia coli UMN026 hypothetical protein YP_002415362.1 4945014 R 585056 CDS YP_002415363.1 218707844 7159385 4945659..4947011 1 NC_011751.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4947011 pmbA 7159385 pmbA Escherichia coli UMN026 peptidase PmbA YP_002415363.1 4945659 D 585056 CDS YP_002415364.1 218707845 7157476 4947194..4947580 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier; soluble cytochrome b562 4947580 cybC 7157476 cybC Escherichia coli UMN026 soluble cytochrome b562 YP_002415364.1 4947194 D 585056 CDS YP_002415365.1 218707846 7156063 complement(4947625..4948089) 1 NC_011751.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4948089 nrdG 7156063 nrdG Escherichia coli UMN026 anaerobic ribonucleotide reductase-activating protein YP_002415365.1 4947625 R 585056 CDS YP_002415366.1 218707847 7157303 complement(4948247..4950385) 1 NC_011751.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4950385 nrdD 7157303 nrdD Escherichia coli UMN026 anaerobic ribonucleoside triphosphate reductase YP_002415366.1 4948247 R 585056 CDS YP_002415367.1 218707848 7157300 complement(4950779..4952434) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme; trehalose-6-phosphate hydrolase 4952434 treC 7157300 treC Escherichia coli UMN026 trehalose-6-phosphate hydrolase YP_002415367.1 4950779 R 585056 CDS YP_002415368.1 218707849 7158104 complement(4952484..4953905) 1 NC_011751.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 4953905 treB 7158104 treB Escherichia coli UMN026 PTS system trehalose(maltose)-specific transporter subunits IIBC YP_002415368.1 4952484 R 585056 CDS YP_002415369.1 218707850 7158103 complement(4954024..4954971) 1 NC_011751.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4954971 treR 7158103 treR Escherichia coli UMN026 trehalose repressor YP_002415369.1 4954024 R 585056 CDS YP_002415370.1 218707851 7158106 4955350..4958046 1 NC_011751.1 P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4958046 mgtA 7158106 mgtA Escherichia coli UMN026 magnesium-transporting ATPase MgtA YP_002415370.1 4955350 D 585056 CDS YP_002415371.1 218707852 7157119 complement(4958252..4958638) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : putative enzyme; ketoacid-binding protein 4958638 yjgF 7157119 yjgF Escherichia coli UMN026 ketoacid-binding protein YP_002415371.1 4958252 R 585056 CDS YP_002415372.1 218707853 7159388 complement(4958711..4959172) 1 NC_011751.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4959172 pyrI 7159388 pyrI Escherichia coli UMN026 aspartate carbamoyltransferase regulatory subunit YP_002415372.1 4958711 R 585056 CDS YP_002415373.1 218707854 7157604 complement(4959185..4960120) 1 NC_011751.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4960120 pyrB 7157604 pyrB Escherichia coli UMN026 aspartate carbamoyltransferase catalytic subunit YP_002415373.1 4959185 R 585056 CDS YP_002415374.1 218707855 7157597 complement(4960124..4960258) 1 NC_011751.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; pyrBI operon leader peptide 4960258 pyrL 7157597 pyrL Escherichia coli UMN026 pyrBI operon leader peptide YP_002415374.1 4960124 R 585056 CDS YP_002415375.1 218707856 7157605 complement(4960539..4960934) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative mRNA endoribonuclease 4960934 yjgH 7157605 yjgH Escherichia coli UMN026 putative mRNA endoribonuclease YP_002415375.1 4960539 R 585056 CDS YP_002415376.1 218707857 7159389 complement(4961065..4961778) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; oxidoreductase 4961778 yjgI 7159389 yjgI Escherichia coli UMN026 oxidoreductase YP_002415376.1 4961065 R 585056 CDS YP_002415377.1 218707858 7159390 4961849..4962442 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative transcriptional regulator 4962442 yjgJ 7159390 yjgJ Escherichia coli UMN026 putative transcriptional regulator YP_002415377.1 4961849 D 585056 CDS YP_002415378.1 218707859 7159391 4962587..4963039 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104; hypothetical protein 4963039 yjgK 7159391 yjgK Escherichia coli UMN026 hypothetical protein YP_002415378.1 4962587 D 585056 CDS YP_002415379.1 218707860 7159395 complement(4964822..4965826) 1 NC_011751.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 4965826 argI 7159395 argI Escherichia coli UMN026 ornithine carbamoyltransferase subunit I YP_002415379.1 4964822 R 585056 CDS YP_002415380.1 218707861 7155775 4965988..4966404 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4966404 yjgD 7155775 yjgD Escherichia coli UMN026 hypothetical protein YP_002415380.1 4965988 D 585056 CDS YP_002415381.1 218707862 7159387 complement(4966450..4966953) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase 4966953 yjgM 7159387 yjgM Escherichia coli UMN026 putative acetyltransferase YP_002415381.1 4966450 R 585056 CDS YP_002415382.1 218707863 7159396 4967146..4968342 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4968342 yjgN 7159396 yjgN Escherichia coli UMN026 hypothetical protein YP_002415382.1 4967146 D 585056 CDS YP_002415383.1 218707864 7159397 complement(4968398..4971253) 1 NC_011751.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4971253 valS 7159397 valS Escherichia coli UMN026 valyl-tRNA synthetase YP_002415383.1 4968398 R 585056 CDS YP_002415384.1 218707865 7158210 complement(4971253..4971696) 1 NC_011751.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4971696 holC 7158210 holC Escherichia coli UMN026 DNA polymerase III subunit chi YP_002415384.1 4971253 R 585056 CDS YP_002415385.1 218707866 7156698 complement(4971952..4973463) 1 NC_011751.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4973463 pepA 7156698 pepA Escherichia coli UMN026 leucyl aminopeptidase YP_002415385.1 4971952 R 585056 CDS YP_002415386.1 218707867 7157410 4973730..4974830 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4974830 yjgP 7157410 yjgP Escherichia coli UMN026 hypothetical protein YP_002415386.1 4973730 D 585056 CDS YP_002415387.1 218707868 7159398 4974830..4975912 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 4975912 yjgQ 7159398 yjgQ Escherichia coli UMN026 hypothetical protein YP_002415387.1 4974830 D 585056 CDS YP_002415388.1 218707869 7159399 complement(4976073..4977575) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative ATPase 4977575 yjgR 7159399 yjgR Escherichia coli UMN026 putative ATPase YP_002415388.1 4976073 R 585056 CDS YP_002415389.1 218707870 7159400 complement(4977653..4978651) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9119199, 98324983, 9658018; Product type r : regulator; DNA-binding transcriptional repressor 4978651 idnR 7159400 idnR Escherichia coli UMN026 DNA-binding transcriptional repressor YP_002415389.1 4977653 R 585056 CDS YP_002415390.1 218707871 7156791 complement(4978718..4980037) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9119199, 93139975, 98324983, 9658018; Product type t : transporter; L-idonate and D-gluconate transporter 4980037 idnT 7156791 idnT Escherichia coli UMN026 L-idonate and D-gluconate transporter YP_002415390.1 4978718 R 585056 CDS YP_002415391.1 218707872 7156792 complement(4980099..4980863) 1 NC_011751.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 4980863 idnO 7156792 idnO Escherichia coli UMN026 gluconate 5-dehydrogenase YP_002415391.1 4980099 R 585056 CDS YP_002415392.1 218707873 7156790 complement(4980887..4981918) 1 NC_011751.1 NAD-binding; L-idonate 5-dehydrogenase 4981918 idnD 7156790 idnD Escherichia coli UMN026 L-idonate 5-dehydrogenase YP_002415392.1 4980887 R 585056 CDS YP_002415393.1 218707874 7156788 4982135..4982698 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87310381, 93139975, 98324983, 9658018, 14832279; Product type e : enzyme; D-gluconate kinase 4982698 idnK 7156788 idnK Escherichia coli UMN026 D-gluconate kinase YP_002415393.1 4982135 D 585056 CDS YP_002415394.1 218707875 7156789 complement(4982702..4983721) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : putative enzyme; putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding 4983721 yjgB 7156789 yjgB Escherichia coli UMN026 putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding YP_002415394.1 4982702 R 585056 CDS YP_002415395.1 218707876 7159386 complement(4983796..4984023) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4984023 7159386 ECUMN_4802 Escherichia coli UMN026 hypothetical protein YP_002415395.1 4983796 R 585056 CDS YP_002415396.1 218707877 7155611 4984262..4985452 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative integrase; KpLE2 phage-like element 4985452 intB 7155611 intB Escherichia coli UMN026 putative integrase; KpLE2 phage-like element YP_002415396.1 4984262 D 585056 CDS YP_002415397.1 218707878 7156843 complement(4985626..4986129) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 4986129 insB 7156843 insB Escherichia coli UMN026 IS1 transposase InsAB'; CP4-6 prophage YP_002415397.1 4985626 R 585056 CDS YP_002415398.1 218707879 7156820 complement(4986048..4986323) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 4986323 insA 7156820 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002415398.1 4986048 R 585056 CDS YP_002415399.1 218707880 7156815 complement(4986477..4987136) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 390404, 390403, 7353655; Product type e : enzyme; chloramphenicol acetyltransferase 4987136 cat 7156815 cat Escherichia coli UMN026 chloramphenicol acetyltransferase YP_002415399.1 4986477 R 585056 CDS YP_002415400.1 218707881 7155920 4987190..4987381 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 4987381 7155920 ECUMN_4807 Escherichia coli UMN026 hypothetical protein YP_002415400.1 4987190 D 585056 CDS YP_002415401.1 218707882 7155485 4987415..4987690 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 4987690 insA 7155485 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002415401.1 4987415 D 585056 CDS YP_002415402.1 218707883 7156816 4987609..4988097 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 4988097 insB 7156816 insB Escherichia coli UMN026 IS1 transposase InsAB'; CP4-6 prophage YP_002415402.1 4987609 D 585056 CDS YP_002415403.1 218707884 7156821 4988126..4988848 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 4988848 7156821 ECUMN_4810 Escherichia coli UMN026 transposase, IS26 YP_002415403.1 4988126 D 585056 CDS YP_002415404.1 218707885 7155486 complement(4988794..4991865) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase TnpA, Tn21 4991865 7155486 ECUMN_4811 Escherichia coli UMN026 transposase TnpA, Tn21 YP_002415404.1 4988794 R 585056 CDS YP_002415405.1 218707886 7155487 complement(4991868..4992428) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; resolvase transposon Tn21 4992428 7155487 ECUMN_4812 Escherichia coli UMN026 resolvase transposon Tn21 YP_002415405.1 4991868 R 585056 CDS YP_002415406.1 218707887 7155488 complement(4992554..4993168) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; protein TnpM, transposon Tn21 4993168 7155488 ECUMN_4813 Escherichia coli UMN026 protein TnpM, transposon Tn21 YP_002415406.1 4992554 R 585056 CDS YP_002415407.1 218707888 7155489 complement(4993107..4994120) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Integrase/recombinase (E2 protein) 4994120 7155489 ECUMN_4814 Escherichia coli UMN026 Integrase/recombinase (E2 protein) YP_002415407.1 4993107 R 585056 CDS YP_002415408.1 218707889 7156160 4994882..4995670 1 NC_011751.1 streptomycin 3'-adenyltransferase; aminoglycoside resistance protein 4995670 aadA 7156160 aadA Escherichia coli UMN026 aminoglycoside resistance protein YP_002415408.1 4994882 D 585056 CDS YP_002415409.1 218707890 7155655 4995885..4996607 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 4996607 7155655 ECUMN_4817 Escherichia coli UMN026 transposase, IS26 YP_002415409.1 4995885 D 585056 CDS YP_002415410.1 218707891 7155491 complement(4996740..4997945) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative chromate ion transporter 4997945 7155491 ECUMN_4818 Escherichia coli UMN026 putative chromate ion transporter YP_002415410.1 4996740 R 585056 CDS YP_002415411.1 218707892 7155493 complement(4998432..4999271) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2662140, 11544236; Product type e : enzyme; dihydropteroate synthase 4999271 sulI 7155493 sulI Escherichia coli UMN026 dihydropteroate synthase YP_002415411.1 4998432 R 585056 CDS YP_002415412.1 218707893 7158012 complement(4999265..4999612) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3054482, 1314803, 8195081; Product type pm : putative membrane component; putative ethidium bromide resistance protein 4999612 ebr 7158012 ebr Escherichia coli UMN026 putative ethidium bromide resistance protein YP_002415412.1 4999265 R 585056 CDS YP_002415413.1 218707894 7156222 complement(4999709..5000431) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 5000431 7156222 ECUMN_4822 Escherichia coli UMN026 transposase, IS26 YP_002415413.1 4999709 R 585056 CDS YP_002415414.1 218707895 7155495 complement(5000932..5001288) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5001288 7155495 ECUMN_4824 Escherichia coli UMN026 hypothetical protein YP_002415414.1 5000932 R 585056 CDS YP_002415415.1 218707896 7155496 complement(5001234..5001818) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8619599, 10960087; Product type r : regulator; regulator of macrolide 2'-phosphotransferase I 5001818 mphR 7155496 mphR Escherichia coli UMN026 regulator of macrolide 2'-phosphotransferase I YP_002415415.1 5001234 R 585056 CDS YP_002415416.1 218707897 7157166 complement(5001818..5003056) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5003056 7157166 ECUMN_4826 Escherichia coli UMN026 hypothetical protein YP_002415416.1 5001818 R 585056 CDS YP_002415417.1 218707898 7155497 complement(5003053..5003958) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8619599, 10960087; Product type e : enzyme; macrolide 2'-phosphotransferase I 5003958 mphA 7155497 mphA Escherichia coli UMN026 macrolide 2'-phosphotransferase I YP_002415417.1 5003053 R 585056 CDS YP_002415418.1 218707899 7157165 complement(5004080..5004802) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, IS26 5004802 7157165 ECUMN_4828 Escherichia coli UMN026 transposase, IS26 YP_002415418.1 5004080 R 585056 CDS YP_002415419.1 218707900 7155499 5005369..5006229 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; beta-lactamase 5006229 bla 7155499 bla Escherichia coli UMN026 beta-lactamase YP_002415419.1 5005369 D 585056 CDS YP_002415420.1 218707901 7155500 complement(5006786..5007289) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type e : enzyme; IS1 transposase InsAB'; CP4-6 prophage 5007289 insB 7155500 insB Escherichia coli UMN026 IS1 transposase InsAB'; CP4-6 prophage YP_002415420.1 5006786 R 585056 CDS YP_002415421.1 218707902 7156822 complement(5007208..5007483) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS1 repressor protein InsA 5007483 insA 7156822 insA Escherichia coli UMN026 IS1 repressor protein InsA YP_002415421.1 5007208 R 585056 CDS YP_002415422.1 218707903 7155502 complement(5008544..5009011) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5009011 7155502 ECUMN_4836 Escherichia coli UMN026 hypothetical protein YP_002415422.1 5008544 R 585056 CDS YP_002415423.1 218707904 7155503 5009146..5009340 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5009340 7155503 ECUMN_4837 Escherichia coli UMN026 hypothetical protein YP_002415423.1 5009146 D 585056 CDS YP_002415424.1 218707905 7155504 5009394..5009615 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5009615 7155504 ECUMN_4838 Escherichia coli UMN026 hypothetical protein YP_002415424.1 5009394 D 585056 CDS YP_002415425.1 218707906 7155505 5010044..5010187 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5010187 7155505 ECUMN_4839 Escherichia coli UMN026 hypothetical protein YP_002415425.1 5010044 D 585056 CDS YP_002415426.1 218707907 7155506 complement(5010215..5011561) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element 5011561 insG 7155506 insG Escherichia coli UMN026 putative IS4 transposase; KpLE2 phage-like element YP_002415426.1 5010215 R 585056 CDS YP_002415427.1 218707908 7156828 5012170..5013387 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative sialic acid transporter 5013387 yjhB 7156828 yjhB Escherichia coli UMN026 putative sialic acid transporter YP_002415427.1 5012170 D 585056 CDS YP_002415428.1 218707909 7159403 5013399..5014517 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase; KpLE2 phage-like element 5014517 yjhC 7159403 yjhC Escherichia coli UMN026 putative oxidoreductase; KpLE2 phage-like element YP_002415428.1 5013399 D 585056 CDS YP_002415429.1 218707910 7159404 complement(5014738..5015133) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5015133 7159404 ECUMN_4843 Escherichia coli UMN026 hypothetical protein YP_002415429.1 5014738 R 585056 CDS YP_002415430.1 218707911 7155507 5014973..5015221 1 NC_011751.1 hypothetical protein 5015221 7155507 ECUMN_4844 Escherichia coli UMN026 hypothetical protein YP_002415430.1 5014973 D 585056 CDS YP_002415431.1 218707912 7155509 5015637..5016476 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS911 5016476 7155509 ECUMN_4846 Escherichia coli UMN026 transposase ORF B, IS911 YP_002415431.1 5015637 D 585056 CDS YP_002415432.1 218707913 7155510 complement(5016887..5018890) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702297; Product type t : transporter; betaine-carnitine-choline transporter family member BetU 5018890 7155510 ECUMN_4848 Escherichia coli UMN026 betaine-carnitine-choline transporter family member BetU YP_002415432.1 5016887 R 585056 CDS YP_002415433.1 218707914 7155511 complement(5019038..5019856) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF B, IS600 5019856 7155511 ECUMN_4849 Escherichia coli UMN026 transposase ORF B, IS600 YP_002415433.1 5019038 R 585056 CDS YP_002415434.1 218707915 7155512 complement(5019941..5021092) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094, 6092059; Product type e : enzyme; IS30 transposase; KpLE2 phage-like element 5021092 insI 7155512 insI Escherichia coli UMN026 IS30 transposase; KpLE2 phage-like element YP_002415434.1 5019941 R 585056 CDS YP_002415435.1 218707916 7157706 complement(5021049..5021417) 1 NC_011751.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase ORF A, IS600 5021417 insM 7157706 insM Escherichia coli UMN026 transposase ORF A, IS600 YP_002415435.1 5021049 R 585056 CDS YP_002415436.1 218707917 7156835 5021433..5022029 1 NC_011751.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; transposase ORF B (fragment), IS911 5022029 insO 7156835 insO Escherichia coli UMN026 transposase ORF B (fragment), IS911 YP_002415436.1 5021433 D 585056 CDS YP_002415437.1 218707918 7156837 5022195..5022608 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5022608 yjhV 7156837 yjhV Escherichia coli UMN026 hypothetical protein YP_002415437.1 5022195 D 585056 CDS YP_002415438.1 218707919 7159415 complement(5023165..5023932) 1 NC_011751.1 Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit 5023932 fecE 7159415 fecE Escherichia coli UMN026 iron-dicitrate transporter ATP-binding subunit YP_002415438.1 5023165 R 585056 CDS YP_002415439.1 218707920 7156328 5023736..5023900 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5023900 7156328 ECUMN_4856 Escherichia coli UMN026 hypothetical protein YP_002415439.1 5023736 D 585056 CDS YP_002415440.1 218707921 7155513 complement(5023933..5024889) 1 NC_011751.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD 5024889 fecD 7155513 fecD Escherichia coli UMN026 iron-dicitrate transporter subunit FecD YP_002415440.1 5023933 R 585056 CDS YP_002415441.1 218707922 7156327 complement(5024886..5025884) 1 NC_011751.1 part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate permease 5025884 fecC 7156327 fecC Escherichia coli UMN026 iron-dicitrate permease YP_002415441.1 5024886 R 585056 CDS YP_002415442.1 218707923 7156326 complement(5025881..5026783) 1 NC_011751.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit 5026783 fecB 7156326 fecB Escherichia coli UMN026 iron-dicitrate transporter substrate-binding subunit YP_002415442.1 5025881 R 585056 CDS YP_002415443.1 218707924 7156325 complement(5026828..5029152) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90105402, 91072220, 92269759, 2836368; Product type t : transporter; ferric citrate outer membrane transporter; KpLE2 phage-like element 5029152 fecA 7156325 fecA Escherichia coli UMN026 ferric citrate outer membrane transporter; KpLE2 phage-like element YP_002415443.1 5026828 R 585056 CDS YP_002415444.1 218707925 7156324 complement(5029239..5030192) 1 NC_011751.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR 5030192 fecR 7156324 fecR Escherichia coli UMN026 fec operon regulator FecR YP_002415444.1 5029239 R 585056 CDS YP_002415445.1 218707926 7156330 complement(5030189..5030710) 1 NC_011751.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI 5030710 fecI 7156330 fecI Escherichia coli UMN026 RNA polymerase sigma factor FecI YP_002415445.1 5030189 R 585056 CDS YP_002415446.1 218707927 7156329 5031002..5031277 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1849492; Product type r : regulator; IS1 repressor protein InsA; KpLE2 phage-like element 5031277 insA 7156329 insA Escherichia coli UMN026 IS1 repressor protein InsA; KpLE2 phage-like element YP_002415446.1 5031002 D 585056 CDS YP_002415447.1 218707928 7156824 complement(5032881..5033072) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5033072 7156824 ECUMN_4866 Escherichia coli UMN026 hypothetical protein YP_002415447.1 5032881 R 585056 CDS YP_002415448.1 218707929 7155514 5033436..5034809 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5034809 7155514 ECUMN_4867 Escherichia coli UMN026 hypothetical protein YP_002415448.1 5033436 D 585056 CDS YP_002415449.1 218707930 7155515 complement(5035048..5036433) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 5036433 7155515 ECUMN_4868 Escherichia coli UMN026 putative transposase YP_002415449.1 5035048 R 585056 CDS YP_002415450.1 218707931 7155516 complement(5036483..5036830) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase ORF2, IS66 family 5036830 7155516 ECUMN_4869 Escherichia coli UMN026 putative transposase ORF2, IS66 family YP_002415450.1 5036483 R 585056 CDS YP_002415451.1 218707932 7155517 complement(5036827..5037228) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase, IS3 family 5037228 7155517 ECUMN_4870 Escherichia coli UMN026 putative transposase, IS3 family YP_002415451.1 5036827 R 585056 CDS YP_002415452.1 218707933 7155518 complement(5037562..5038083) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5038083 7155518 ECUMN_4871 Escherichia coli UMN026 hypothetical protein YP_002415452.1 5037562 R 585056 CDS YP_002415453.1 218707934 7155519 complement(5037984..5038391) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5038391 7155519 ECUMN_4872 Escherichia coli UMN026 hypothetical protein YP_002415453.1 5037984 R 585056 CDS YP_002415454.1 218707935 7155520 complement(5038645..5039250) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5039250 7155520 ECUMN_4873 Escherichia coli UMN026 hypothetical protein YP_002415454.1 5038645 R 585056 CDS YP_002415455.1 218707936 7155521 complement(5039828..5039995) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5039995 7155521 ECUMN_4875 Escherichia coli UMN026 hypothetical protein YP_002415455.1 5039828 R 585056 CDS YP_002415456.1 218707937 7155522 5040543..5040944 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5040944 7155522 ECUMN_4876 Escherichia coli UMN026 hypothetical protein YP_002415456.1 5040543 D 585056 CDS YP_002415457.1 218707938 7155523 5041024..5041641 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5041641 7155523 ECUMN_4877 Escherichia coli UMN026 hypothetical protein YP_002415457.1 5041024 D 585056 CDS YP_002415458.1 218707939 7155524 complement(5041963..5043516) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5043516 7155524 ECUMN_4878 Escherichia coli UMN026 hypothetical protein YP_002415458.1 5041963 R 585056 CDS YP_002415459.1 218707940 7155525 5044091..5044351 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 5044351 7155525 ECUMN_4879 Escherichia coli UMN026 hypothetical protein YP_002415459.1 5044091 D 585056 CDS YP_002415460.1 218707941 7155526 5044639..5045550 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5045550 7155526 ECUMN_4880 Escherichia coli UMN026 hypothetical protein YP_002415460.1 5044639 D 585056 CDS YP_002415461.1 218707942 7155527 5045922..5049041 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392470, 97257509, 99212225, 2661530, 9298646; Product type h : extrachromosomal origin; antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage 5049041 flu 7155527 flu Escherichia coli UMN026 antigen 43 (Ag43) phase-variable biofilm formation autotransporter; CP4-44 prophage YP_002415461.1 5045922 D 585056 CDS YP_002415462.1 218707943 7156418 5049076..5049270 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5049270 7156418 ECUMN_4882 Escherichia coli UMN026 hypothetical protein YP_002415462.1 5049076 D 585056 CDS YP_002415463.1 218707944 7155528 5049425..5050243 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5050243 7155528 ECUMN_4883 Escherichia coli UMN026 hypothetical protein YP_002415463.1 5049425 D 585056 CDS YP_002415464.1 218707945 7155529 5050204..5051058 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5051058 7155529 ECUMN_4884 Escherichia coli UMN026 hypothetical protein YP_002415464.1 5050204 D 585056 CDS YP_002415465.1 218707946 7155530 5051059..5051550 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor; putative DNA repair protein; CP4-44 prophage 5051550 yeeS 7155530 yeeS Escherichia coli UMN026 putative DNA repair protein; CP4-44 prophage YP_002415465.1 5051059 D 585056 CDS YP_002415466.1 218707947 7158809 5051613..5051834 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 5051834 yeeT 7158809 yeeT Escherichia coli UMN026 hypothetical protein YP_002415466.1 5051613 D 585056 CDS YP_002415467.1 218707948 7158811 5051834..5051947 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5051947 7158811 ECUMN_4887 Escherichia coli UMN026 hypothetical protein YP_002415467.1 5051834 D 585056 CDS YP_002415468.1 218707949 7155531 5051889..5052365 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5052365 7155531 ECUMN_4888 Escherichia coli UMN026 hypothetical protein YP_002415468.1 5051889 D 585056 CDS YP_002415469.1 218707950 7155532 5053293..5054552 1 NC_011751.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase 5054552 mtnK 7155532 mtnK Escherichia coli UMN026 methylthioribose kinase YP_002415469.1 5053293 D 585056 CDS YP_002415470.1 218707951 7157196 5054562..5055677 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15102328; Product type e : enzyme; methyl-thioribose-1-phosphate isomerase 5055677 mtnA 7157196 mtnA Escherichia coli UMN026 methyl-thioribose-1-phosphate isomerase YP_002415470.1 5054562 D 585056 CDS YP_002415471.1 218707952 7157194 5055708..5056349 1 NC_011751.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase 5056349 mtnB 7157194 mtnB Escherichia coli UMN026 L-fuculose phosphate aldolase YP_002415471.1 5055708 D 585056 CDS YP_002415472.1 218707953 7157195 5056453..5057457 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative integral membrane protein 5057457 7157195 ECUMN_4892 Escherichia coli UMN026 putative integral membrane protein YP_002415472.1 5056453 D 585056 CDS YP_002415473.1 218707954 7155533 complement(5057498..5058484) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element 5058484 yjhU 7155533 yjhU Escherichia coli UMN026 putative DNA-binding transcriptional regulator; KpLE2 phage-like element YP_002415473.1 5057498 R 585056 CDS YP_002415474.1 218707955 7159414 complement(5058584..5058775) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5058775 7159414 ECUMN_4894 Escherichia coli UMN026 hypothetical protein YP_002415474.1 5058584 R 585056 CDS YP_002415475.1 218707956 7155534 complement(5058831..5060180) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative transporter; KpLE2 phage-like element 5060180 yjhF 7155534 yjhF Escherichia coli UMN026 putative transporter; KpLE2 phage-like element YP_002415475.1 5058831 R 585056 CDS YP_002415476.1 218707957 7159405 complement(5060287..5062254) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; hypothetical protein 5062254 yjhG 7159405 yjhG Escherichia coli UMN026 hypothetical protein YP_002415476.1 5060287 R 585056 CDS YP_002415477.1 218707958 7159406 complement(5062265..5063170) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11425723; Product type pe : putative enzyme; putative lyase/synthase (dapA-like); KpLE2 phage-like element 5063170 yjhH 7159406 yjhH Escherichia coli UMN026 putative lyase/synthase (dapA-like); KpLE2 phage-like element YP_002415477.1 5062265 R 585056 CDS YP_002415478.1 218707959 7159407 complement(5063175..5063963) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element 5063963 yjhI 7159407 yjhI Escherichia coli UMN026 putative DNA-binding transcriptional regulator; KpLE2 phage-like element YP_002415478.1 5063175 R 585056 CDS YP_002415479.1 218707960 7159408 complement(5064266..5065048) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator; KpLE2 phage-like element 5065048 sgcR 7159408 sgcR Escherichia coli UMN026 putative DNA-binding transcriptional regulator; KpLE2 phage-like element YP_002415479.1 5064266 R 585056 CDS YP_002415480.1 218707961 7157919 complement(5065065..5065697) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; epimerase 5065697 sgcE 7157919 sgcE Escherichia coli UMN026 epimerase YP_002415480.1 5065065 R 585056 CDS YP_002415481.1 218707962 7157917 complement(5065709..5066140) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase enzyme IIA component; KpLE2 phage-like element 5066140 sgcA 7157917 sgcA Escherichia coli UMN026 putative phosphotransferase enzyme IIA component; KpLE2 phage-like element YP_002415481.1 5065709 R 585056 CDS YP_002415482.1 218707963 7157858 complement(5066271..5067077) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative nucleoside triphosphatase; KpLE2 phage-like element 5067077 sgcQ 7157858 sgcQ Escherichia coli UMN026 putative nucleoside triphosphatase; KpLE2 phage-like element YP_002415482.1 5066271 R 585056 CDS YP_002415483.1 218707964 7157918 complement(5067090..5068403) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative phosphotransferase enzyme IIC component; KpLE2 phage-like element 5068403 sgcC 7157918 sgcC Escherichia coli UMN026 putative phosphotransferase enzyme IIC component; KpLE2 phage-like element YP_002415483.1 5067090 R 585056 CDS YP_002415484.1 218707965 7157916 complement(5068415..5068693) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter; putative enzyme IIB component of PTS; KpLE2 phage-like element 5068693 sgcB 7157916 sgcB Escherichia coli UMN026 putative enzyme IIB component of PTS; KpLE2 phage-like element YP_002415484.1 5068415 R 585056 CDS YP_002415485.1 218707966 7157915 complement(5068690..5069811) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative endoglucanase with Zn-dependent exopeptidase domain; KpLE2 phage-like element 5069811 sgcX 7157915 sgcX Escherichia coli UMN026 putative endoglucanase with Zn-dependent exopeptidase domain; KpLE2 phage-like element YP_002415485.1 5068690 R 585056 CDS YP_002415486.1 218707967 7157920 complement(5070597..5071343) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative methyltransferase; KpLE2 phage-like element 5071343 yjhP 7157920 yjhP Escherichia coli UMN026 putative methyltransferase; KpLE2 phage-like element YP_002415486.1 5070597 R 585056 CDS YP_002415487.1 218707968 7159409 complement(5071399..5071944) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative acetyltransferase; KpLE2 phage-like element 5071944 yjhQ 7159409 yjhQ Escherichia coli UMN026 putative acetyltransferase; KpLE2 phage-like element YP_002415487.1 5071399 R 585056 CDS YP_002415488.1 218707969 7159410 complement(5071956..5072213) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5072213 yjhX 7159410 yjhX Escherichia coli UMN026 hypothetical protein YP_002415488.1 5071956 R 585056 CDS YP_002415489.1 218707970 7159416 complement(5072704..5072835) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5072835 7159416 ECUMN_4909 Escherichia coli UMN026 hypothetical protein YP_002415489.1 5072704 R 585056 CDS YP_002415490.1 218707971 7155536 5073175..5074191 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96367099; Product type pf : putative factor; putative frameshift suppressor; KpLE2 phage-like element 5074191 yjhR 7155536 yjhR Escherichia coli UMN026 putative frameshift suppressor; KpLE2 phage-like element YP_002415490.1 5073175 D 585056 CDS YP_002415491.1 218707972 7159411 complement(5074306..5074482) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5074482 7159411 ECUMN_4912 Escherichia coli UMN026 hypothetical protein YP_002415491.1 5074306 R 585056 CDS YP_002415492.1 218707973 7155537 5074342..5075358 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin; IS5 transposase and trans-activator; CP4-44 prophage 5075358 insH 7155537 insH Escherichia coli UMN026 IS5 transposase and trans-activator; CP4-44 prophage YP_002415492.1 5074342 D 585056 CDS YP_002415493.1 218707974 7156833 complement(5075973..5076953) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5076953 yjhS 7156833 yjhS Escherichia coli UMN026 hypothetical protein YP_002415493.1 5075973 R 585056 CDS YP_002415494.1 218707975 7159412 complement(5077018..5078124) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; N-acetylneuraminic acid mutarotase 5078124 yjhT 7159412 yjhT Escherichia coli UMN026 N-acetylneuraminic acid mutarotase YP_002415494.1 5077018 R 585056 CDS YP_002415495.1 218707976 7159413 complement(5078144..5078860) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15743943; Product type t : transporter; N-acetylnuraminic acid outer membrane channel protein 5078860 yjhA 7159413 yjhA Escherichia coli UMN026 N-acetylnuraminic acid outer membrane channel protein YP_002415495.1 5078144 R 585056 CDS YP_002415496.1 218707977 7159402 5079229..5079378 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5079378 7159402 ECUMN_4917 Escherichia coli UMN026 hypothetical protein YP_002415496.1 5079229 D 585056 CDS YP_002415497.1 218707978 7155538 complement(5079660..5080055) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5080055 7155538 ECUMN_4918 Escherichia coli UMN026 hypothetical protein YP_002415497.1 5079660 R 585056 CDS YP_002415498.1 218707979 7155539 5080316..5080918 1 NC_011751.1 inversion of on/off regulator of fimA; tyrosine recombinase 5080918 fimB 7155539 fimB Escherichia coli UMN026 tyrosine recombinase YP_002415498.1 5080316 D 585056 CDS YP_002415499.1 218707980 7156357 5081396..5081992 1 NC_011751.1 inversion of on/off regulator of fimA; tyrosine recombinase 5081992 fimE 7156357 fimE Escherichia coli UMN026 tyrosine recombinase YP_002415499.1 5081396 D 585056 CDS YP_002415500.1 218707981 7156360 5082474..5083022 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6146599, 6147250, 90220509, 93106965, 2858471, 6123483; Product type s : structure; major type 1 subunit fimbrin 5083022 fimA 7156360 fimA Escherichia coli UMN026 major type 1 subunit fimbrin YP_002415500.1 5082474 D 585056 CDS YP_002415501.1 218707982 7156356 5083087..5083626 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12897022, 11673421, 6147250; Product type s : structure; type 1 pilus biosynthesis fimbrial protein 5083626 fimI 7156356 fimI Escherichia coli UMN026 type 1 pilus biosynthesis fimbrial protein YP_002415501.1 5083087 D 585056 CDS YP_002415502.1 218707983 7156364 5083663..5084388 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20450729, 90220509, 93155127, 93391362, 1363735, 8104335, 8636962, 9783748; Product type f : factor; chaperone, periplasmic 5084388 fimC 7156364 fimC Escherichia coli UMN026 chaperone, periplasmic YP_002415502.1 5083663 D 585056 CDS YP_002415503.1 218707984 7156358 5084455..5087091 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12842468, 90220509, 1970114; Product type f : factor; outer membrane usher protein, type 1 fimbrial synthesis 5087091 fimD 7156358 fimD Escherichia coli UMN026 outer membrane usher protein, type 1 fimbrial synthesis YP_002415503.1 5084455 D 585056 CDS YP_002415504.1 218707985 7156359 5087101..5087631 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 1970114, 2890081; Product type s : structure; minor component of type 1 fimbriae 5087631 fimF 7156359 fimF Escherichia coli UMN026 minor component of type 1 fimbriae YP_002415504.1 5087101 D 585056 CDS YP_002415505.1 218707986 7156361 5087644..5088147 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 92394896, 2890081; Product type s : structure; minor component of type 1 fimbriae 5088147 fimG 7156361 fimG Escherichia coli UMN026 minor component of type 1 fimbriae YP_002415505.1 5087644 D 585056 CDS YP_002415506.1 218707987 7156362 5088167..5089069 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 93155127, 93391362, 1971261, 2890081, 2900235; Product type s : structure; minor component of type 1 fimbriae 5089069 fimH 7156362 fimH Escherichia coli UMN026 minor component of type 1 fimbriae YP_002415506.1 5088167 D 585056 CDS YP_002415507.1 218707988 7156363 complement(5089312..5090655) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125229, 15516583, 8550444; Product type t : transporter; fructuronate transporter 5090655 gntP 7156363 gntP Escherichia coli UMN026 fructuronate transporter YP_002415507.1 5089312 R 585056 CDS YP_002415508.1 218707989 7156596 5090735..5091043 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5091043 7156596 ECUMN_4929 Escherichia coli UMN026 hypothetical protein YP_002415508.1 5090735 D 585056 CDS YP_002415509.1 218707990 7155540 5090995..5092179 1 NC_011751.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5092179 uxuA 7155540 uxuA Escherichia coli UMN026 mannonate dehydratase YP_002415509.1 5090995 D 585056 CDS YP_002415510.1 218707991 7158206 5092260..5093720 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme; D-mannonate oxidoreductase, NAD-binding 5093720 uxuB 7158206 uxuB Escherichia coli UMN026 D-mannonate oxidoreductase, NAD-binding YP_002415510.1 5092260 D 585056 CDS YP_002415511.1 218707992 7158207 5093935..5094708 1 NC_011751.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5094708 uxuR 7158207 uxuR Escherichia coli UMN026 DNA-binding transcriptional repressor UxuR YP_002415511.1 5093935 D 585056 CDS YP_002415512.1 218707993 7158208 complement(5094849..5095679) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5095679 yjiC 7158208 yjiC Escherichia coli UMN026 hypothetical protein YP_002415512.1 5094849 R 585056 CDS YP_002415513.1 218707994 7159418 5096243..5096386 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5096386 7159418 ECUMN_4934 Escherichia coli UMN026 hypothetical protein YP_002415513.1 5096243 D 585056 CDS YP_002415514.1 218707995 7155541 5096352..5096744 1 NC_011751.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5096744 iraD 7155541 iraD Escherichia coli UMN026 DNA replication/recombination/repair protein YP_002415514.1 5096352 D 585056 CDS YP_002415515.1 218707996 7159419 complement(5096737..5097648) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 5097648 yjiE 7159419 yjiE Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415515.1 5096737 R 585056 CDS YP_002415516.1 218707997 7159420 complement(5097713..5098885) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95181377, 7876157; Product type e : enzyme; isoaspartyl dipeptidase 5098885 iadA 7159420 iadA Escherichia coli UMN026 isoaspartyl dipeptidase YP_002415516.1 5097713 R 585056 CDS YP_002415517.1 218707998 7156778 complement(5098898..5099359) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5099359 yjiG 7156778 yjiG Escherichia coli UMN026 hypothetical protein YP_002415517.1 5098898 R 585056 CDS YP_002415518.1 218707999 7159421 complement(5099356..5100039) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5100039 yjiH 7159421 yjiH Escherichia coli UMN026 hypothetical protein YP_002415518.1 5099356 R 585056 CDS YP_002415519.1 218708000 7159422 5100289..5100843 1 NC_011751.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 5100843 kptA 7159422 kptA Escherichia coli UMN026 RNA 2'-phosphotransferase-like protein YP_002415519.1 5100289 D 585056 CDS YP_002415520.1 218708001 7156917 complement(5100856..5102034) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5102034 yjiJ 7156917 yjiJ Escherichia coli UMN026 hypothetical protein YP_002415520.1 5100856 R 585056 CDS YP_002415521.1 218708002 7159423 complement(5102102..5103070) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5103070 yjiK 7159423 yjiK Escherichia coli UMN026 hypothetical protein YP_002415521.1 5102102 R 585056 CDS YP_002415522.1 218708003 7159424 complement(5103027..5103284) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5103284 7159424 ECUMN_4944 Escherichia coli UMN026 hypothetical protein YP_002415522.1 5103027 R 585056 CDS YP_002415523.1 218708004 7155542 complement(5103281..5104048) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8365476, 7607244, 15654892; Product type e : enzyme; ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 5104048 hgdC 7155542 hgdC Escherichia coli UMN026 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase YP_002415523.1 5103281 R 585056 CDS YP_002415524.1 218708005 7156668 complement(5104058..5105209) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3691501, 11106419; Product type pe : putative enzyme; putative 2-hydroxyglutaryl-CoA dehydratase (hgdB-like) 5105209 yjiM 7156668 yjiM Escherichia coli UMN026 putative 2-hydroxyglutaryl-CoA dehydratase (hgdB-like) YP_002415524.1 5104058 R 585056 CDS YP_002415525.1 218708006 7159425 complement(5105325..5106605) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5106605 yjiN 7159425 yjiN Escherichia coli UMN026 hypothetical protein YP_002415525.1 5105325 R 585056 CDS YP_002415526.1 218708007 7159426 complement(5106646..5107878) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug efflux system protein 5107878 yjiO 7159426 yjiO Escherichia coli UMN026 multidrug efflux system protein YP_002415526.1 5106646 R 585056 CDS YP_002415527.1 218708008 7159427 5108357..5109277 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transposase 5109277 7159427 ECUMN_4949 Escherichia coli UMN026 putative transposase YP_002415527.1 5108357 D 585056 CDS YP_002415528.1 218708009 7155543 complement(5109521..5110933) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator/putative aminotransferase 5110933 yjiR 7155543 yjiR Escherichia coli UMN026 putative DNA-binding transcriptional regulator/putative aminotransferase YP_002415528.1 5109521 R 585056 CDS YP_002415529.1 218708010 7159428 5111725..5115063 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5115063 yjgt 7159428 yjgt Escherichia coli UMN026 hypothetical protein YP_002415529.1 5111725 D 585056 CDS YP_002415530.1 218708011 7159401 5115076..5121420 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative DEAD-box helicase-like protein 5121420 7159401 ECUMN_4953 Escherichia coli UMN026 putative DEAD-box helicase-like protein YP_002415530.1 5115076 D 585056 CDS YP_002415531.1 218708012 7155544 complement(5121477..5122523) 1 NC_011751.1 McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC 5122523 mcrC 7155544 mcrC Escherichia coli UMN026 5-methylcytosine-specific restriction enzyme subunit McrC YP_002415531.1 5121477 R 585056 CDS YP_002415532.1 218708013 7157067 complement(5122523..5123902) 1 NC_011751.1 McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB 5123902 mcrB 7157067 mcrB Escherichia coli UMN026 5-methylcytosine-specific restriction enzyme subunit McrB YP_002415532.1 5122523 R 585056 CDS YP_002415533.1 218708014 7157066 complement(5124064..5124462) 1 NC_011751.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 5124462 yjiW 7157066 yjiW Escherichia coli UMN026 endoribonuclease SymE YP_002415533.1 5124064 R 585056 CDS YP_002415534.1 218708015 7157859 complement(5124633..5126027) 1 NC_011751.1 specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS 5126027 hsdS 7157859 hsdS Escherichia coli UMN026 EcoKI restriction-modification system protein HsdS YP_002415534.1 5124633 R 585056 CDS YP_002415535.1 218708016 7156719 complement(5126024..5127613) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88118919, 91216450, 3323532; Product type e : enzyme; DNA methylase M 5127613 hsdM 7156719 hsdM Escherichia coli UMN026 DNA methylase M YP_002415535.1 5126024 R 585056 CDS YP_002415536.1 218708017 7156717 complement(5127814..5131326) 1 NC_011751.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 5131326 hsdR 7156717 hsdR Escherichia coli UMN026 type I restriction enzyme EcoKI subunit R YP_002415536.1 5127814 R 585056 CDS YP_002415537.1 218708018 7156718 5131514..5132428 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193234, 91317743, 1650347; Product type e : enzyme; methylated adenine and cytosine restriction protein 5132428 mrr 7156718 mrr Escherichia coli UMN026 methylated adenine and cytosine restriction protein YP_002415537.1 5131514 D 585056 CDS YP_002415538.1 218708019 7157183 complement(5132474..5133430) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : putative enzyme; putative GTP-binding protein YjiA 5133430 yjiA 7157183 yjiA Escherichia coli UMN026 putative GTP-binding protein YjiA YP_002415538.1 5132474 R 585056 CDS YP_002415539.1 218708020 7159417 complement(5133441..5133644) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5133644 yjiX 7159417 yjiX Escherichia coli UMN026 hypothetical protein YP_002415539.1 5133441 R 585056 CDS YP_002415540.1 218708021 7159430 complement(5133694..5135844) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5135844 yjiY 7159430 yjiY Escherichia coli UMN026 hypothetical protein YP_002415540.1 5133694 R 585056 CDS YP_002415541.1 218708022 7159431 complement(5136012..5136158) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5136158 7159431 ECUMN_4964 Escherichia coli UMN026 hypothetical protein YP_002415541.1 5136012 R 585056 CDS YP_002415542.1 218708023 7155545 complement(5136237..5136749) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10633095; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase small component 5136749 hpaC 7155545 hpaC Escherichia coli UMN026 4-hydroxyphenylacetate 3-monooxygenase small component YP_002415542.1 5136237 R 585056 CDS YP_002415543.1 218708024 7156703 complement(5136767..5138329) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10653707; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase large component 5138329 hpaB 7156703 hpaB Escherichia coli UMN026 4-hydroxyphenylacetate 3-monooxygenase large component YP_002415543.1 5136767 R 585056 CDS YP_002415544.1 218708025 7156702 complement(5138580..5139470) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403; Product type r : regulator; regulator of the 4HPA-hydroxylase operon 5139470 hpaA 7156702 hpaA Escherichia coli UMN026 regulator of the 4HPA-hydroxylase operon YP_002415544.1 5138580 R 585056 CDS YP_002415545.1 218708026 7156701 complement(5139480..5140916) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8550403, 14744977; Product type pt : putative transporter; putative 4-hydroxyphenylacetate permease hpaX 5140916 7156701 ECUMN_4968 Escherichia coli UMN026 putative 4-hydroxyphenylacetate permease hpaX YP_002415545.1 5139480 R 585056 CDS YP_002415546.1 218708027 7155546 complement(5141031..5141837) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8529896, 8550403; Product type e : enzyme; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 5141837 hpaI 7155546 hpaI Escherichia coli UMN026 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_002415546.1 5141031 R 585056 CDS YP_002415547.1 218708028 7156709 complement(5141868..5143214) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative IS4 transposase; KpLE2 phage-like element 5143214 insG 7156709 insG Escherichia coli UMN026 putative IS4 transposase; KpLE2 phage-like element YP_002415547.1 5141868 R 585056 CDS YP_002415548.1 218708029 7156829 complement(5143253..5144089) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403, 9492273; Product type e : enzyme; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 5144089 hpaH 7156829 hpaH Escherichia coli UMN026 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_002415548.1 5143253 R 585056 CDS YP_002415549.1 218708030 7156708 complement(5144139..5144519) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2194841; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 5144519 hpaF 7156708 hpaF Escherichia coli UMN026 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_002415549.1 5144139 R 585056 CDS YP_002415550.1 218708031 7156706 complement(5144529..5145380) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403; Product type e : enzyme; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 5145380 hpaD 7156706 hpaD Escherichia coli UMN026 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_002415550.1 5144529 R 585056 CDS YP_002415551.1 218708032 7156704 complement(5145382..5146848) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737515, 2061311, 8550403; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 5146848 hpaE 7156704 hpaE Escherichia coli UMN026 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_002415551.1 5145382 R 585056 CDS YP_002415552.1 218708033 7156705 complement(5146845..5148140) 1 NC_011751.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223600, 8384293, 11863436; Product type e : enzyme; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase 5148140 hpaG 7156705 hpaG Escherichia coli UMN026 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase YP_002415552.1 5146845 R 585056 CDS YP_002415553.1 218708034 7156707 5148352..5148852 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8384293, 8550403; Product type r : regulator; 4-hydroxyphenylacetate degradative operon repressor 5148852 hpaR 7156707 hpaR Escherichia coli UMN026 4-hydroxyphenylacetate degradative operon repressor YP_002415553.1 5148352 D 585056 CDS YP_002415554.1 218708035 7156710 5148971..5150635 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator; methyl-accepting chemotaxis protein I, serine sensor receptor 5150635 tsr 7156710 tsr Escherichia coli UMN026 methyl-accepting chemotaxis protein I, serine sensor receptor YP_002415554.1 5148971 D 585056 CDS YP_002415555.1 218708036 7159433 complement(5152260..5153174) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 5153174 yjjM 7159433 yjjM Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415555.1 5152260 R 585056 CDS YP_002415556.1 218708037 7159438 5153313..5154335 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative oxidoreductase 5154335 yjjN 7159438 yjjN Escherichia coli UMN026 putative oxidoreductase YP_002415556.1 5153313 D 585056 CDS YP_002415557.1 218708038 7159439 complement(5154475..5156766) 1 NC_011751.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 5156766 mdoB 7159439 mdoB Escherichia coli UMN026 phosphoglycerol transferase I YP_002415557.1 5154475 R 585056 CDS YP_002415558.1 218708039 7157072 complement(5157020..5157514) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5157514 yjjA 7157072 yjjA Escherichia coli UMN026 hypothetical protein YP_002415558.1 5157020 R 585056 CDS YP_002415559.1 218708040 7159434 complement(5157563..5158300) 1 NC_011751.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 5158300 dnaC 7159434 dnaC Escherichia coli UMN026 DNA replication protein DnaC YP_002415559.1 5157563 R 585056 CDS YP_002415560.1 218708041 7156185 complement(5158303..5158842) 1 NC_011751.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 5158842 dnaT 7156185 dnaT Escherichia coli UMN026 primosomal protein DnaI YP_002415560.1 5158303 R 585056 CDS YP_002415561.2 229598882 7156192 complement(5158949..5159422) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5159422 7156192 ECUMN_4986 Escherichia coli UMN026 hypothetical protein YP_002415561.2 5158949 R 585056 CDS YP_002415562.1 218708043 7155547 complement(5159413..5160183) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component; hypothetical protein 5160183 yjjP 7155547 yjjP Escherichia coli UMN026 hypothetical protein YP_002415562.1 5159413 R 585056 CDS YP_002415563.1 218708044 7159440 5160802..5161527 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative DNA-binding transcriptional regulator 5161527 yjjQ 7159440 yjjQ Escherichia coli UMN026 putative DNA-binding transcriptional regulator YP_002415563.1 5160802 D 585056 CDS YP_002415564.1 218708045 7159441 5161539..5162162 1 NC_011751.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5162162 bglJ 7159441 bglJ Escherichia coli UMN026 DNA-binding transcriptional activator BglJ YP_002415564.1 5161539 D 585056 CDS YP_002415565.1 218708046 7155874 complement(5162200..5162988) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier; ferric iron reductase 5162988 fhuF 7155874 fhuF Escherichia coli UMN026 ferric iron reductase YP_002415565.1 5162200 R 585056 CDS YP_002415566.1 218708047 7156349 5163018..5163365 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5163365 7156349 ECUMN_4991 Escherichia coli UMN026 hypothetical protein YP_002415566.1 5163018 D 585056 CDS YP_002415567.1 218708048 7155612 complement(5164105..5165136) 1 NC_011751.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 5165136 rsmC 7155612 rsmC Escherichia coli UMN026 16S ribosomal RNA m2G1207 methyltransferase YP_002415567.1 5164105 R 585056 CDS YP_002415568.1 218708049 7157798 5165239..5165652 1 NC_011751.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5165652 holD 7157798 holD Escherichia coli UMN026 DNA polymerase III subunit psi YP_002415568.1 5165239 D 585056 CDS YP_002415569.1 218708050 7156699 5165621..5166067 1 NC_011751.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5166067 rimI 7156699 rimI Escherichia coli UMN026 ribosomal-protein-alanine N-acetyltransferase YP_002415569.1 5165621 D 585056 CDS YP_002415570.1 218708051 7157691 5166082..5166759 1 NC_011751.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5166759 yjjG 7157691 yjjG Escherichia coli UMN026 nucleotidase YP_002415570.1 5166082 D 585056 CDS YP_002415571.1 218708052 7159435 5166850..5168439 1 NC_011751.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5168439 prfC 7159435 prfC Escherichia coli UMN026 peptide chain release factor 3 YP_002415571.1 5166850 D 585056 CDS YP_002415572.1 218708053 7157519 5168832..5169437 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process; periplasmic protein 5169437 osmY 7157519 osmY Escherichia coli UMN026 periplasmic protein YP_002415572.1 5168832 D 585056 CDS YP_002415573.1 218708054 7157366 5169546..5169725 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5169725 ytjA 7157366 ytjA Escherichia coli UMN026 hypothetical protein YP_002415573.1 5169546 D 585056 CDS YP_002415574.1 218708055 7159681 5169847..5170920 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative esterase 5170920 yjjU 7159681 yjjU Escherichia coli UMN026 putative esterase YP_002415574.1 5169847 D 585056 CDS YP_002415575.1 218708056 7159442 5170917..5171696 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative deoxyribonuclease YjjV 5171696 yjjV 7159442 yjjV Escherichia coli UMN026 putative deoxyribonuclease YjjV YP_002415575.1 5170917 D 585056 CDS YP_002415576.1 218708057 7159443 complement(5172215..5173078) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative pyruvate formate lyase activating enzyme 5173078 yjjW 7159443 yjjW Escherichia coli UMN026 putative pyruvate formate lyase activating enzyme YP_002415576.1 5172215 R 585056 CDS YP_002415577.1 218708058 7159444 complement(5173050..5174600) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5174600 yjjI 7159444 yjjI Escherichia coli UMN026 hypothetical protein YP_002415577.1 5173050 R 585056 CDS YP_002415578.1 218708059 7159436 5174858..5175637 1 NC_011751.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5175637 deoC 7159436 deoC Escherichia coli UMN026 deoxyribose-phosphate aldolase YP_002415578.1 5174858 D 585056 CDS YP_002415579.1 218708060 7156142 5175863..5177185 1 NC_011751.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5177185 deoA 7156142 deoA Escherichia coli UMN026 thymidine phosphorylase YP_002415579.1 5175863 D 585056 CDS YP_002415580.1 218708061 7156140 5177237..5178460 1 NC_011751.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5178460 deoB 7156140 deoB Escherichia coli UMN026 phosphopentomutase YP_002415580.1 5177237 D 585056 CDS YP_002415581.1 218708062 7156141 5178517..5179236 1 NC_011751.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5179236 deoD 7156141 deoD Escherichia coli UMN026 purine nucleoside phosphorylase YP_002415581.1 5178517 D 585056 CDS YP_002415582.1 218708063 7156143 complement(5179420..5179647) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; putative transcriptionnal regulator 5179647 7156143 ECUMN_5009 Escherichia coli UMN026 putative transcriptionnal regulator YP_002415582.1 5179420 R 585056 CDS YP_002415583.1 218708064 7155549 complement(5179679..5180695) 1 NC_011751.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 5180695 lplA 7155549 lplA Escherichia coli UMN026 lipoate-protein ligase A YP_002415583.1 5179679 R 585056 CDS YP_002415584.1 218708065 7157005 complement(5180723..5181367) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780; hypothetical protein 5181367 ytjB 7157005 ytjB Escherichia coli UMN026 hypothetical protein YP_002415584.1 5180723 R 585056 CDS YP_002415585.1 218708066 7159682 5181473..5182441 1 NC_011751.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5182441 serB 7159682 serB Escherichia coli UMN026 phosphoserine phosphatase YP_002415585.1 5181473 D 585056 CDS YP_002415586.1 218708067 7157898 5182490..5183872 1 NC_011751.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5183872 radA 7157898 radA Escherichia coli UMN026 DNA repair protein RadA YP_002415586.1 5182490 D 585056 CDS YP_002415587.1 218708068 7157616 5183893..5185125 1 NC_011751.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5185125 nadR 7157616 nadR Escherichia coli UMN026 nicotinamide-nucleotide adenylyltransferase YP_002415587.1 5183893 D 585056 CDS YP_002415588.1 218708069 7157226 complement(5185312..5185437) 1 NC_011751.1 Evidence 6 : Doubtful CDS; hypothetical protein 5185437 7157226 ECUMN_5015 Escherichia coli UMN026 hypothetical protein YP_002415588.1 5185312 R 585056 CDS YP_002415589.1 218708070 7155550 complement(5185352..5185537) 1 NC_011751.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 5185537 7155550 ECUMN_5016 Escherichia coli UMN026 hypothetical protein YP_002415589.1 5185352 R 585056 CDS YP_002415590.1 218708071 7155551 complement(5185586..5185798) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5185798 7155551 ECUMN_5017 Escherichia coli UMN026 hypothetical protein YP_002415590.1 5185586 R 585056 CDS YP_002415591.1 218708072 7155552 complement(5185956..5186372) 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5186372 7155552 ECUMN_5018 Escherichia coli UMN026 hypothetical protein YP_002415591.1 5185956 R 585056 CDS YP_002415592.1 218708073 7155553 complement(5186398..5187297) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9537320; Product type pe : putative enzyme; putative 3-oxoacyl-[acyl-carrier-protein] reductase 5187297 7155553 ECUMN_5019 Escherichia coli UMN026 putative 3-oxoacyl-[acyl-carrier-protein] reductase YP_002415592.1 5186398 R 585056 CDS YP_002415593.1 218708074 7155554 complement(5187215..5188225) 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; putative Aldo/keto reductase 5188225 7155554 ECUMN_5020 Escherichia coli UMN026 putative Aldo/keto reductase YP_002415593.1 5187215 R 585056 CDS YP_002415594.1 218708075 7155555 5188266..5189246 1 NC_011751.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; putative HTH-type transcriptional regulator alsR 5189246 7155555 ECUMN_5021 Escherichia coli UMN026 putative HTH-type transcriptional regulator alsR YP_002415594.1 5188266 D 585056 CDS YP_002415595.1 218708076 7155556 complement(5189402..5191069) 1 NC_011751.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 5191069 yjjK 7155556 yjjK Escherichia coli UMN026 putative ABC transporter ATP-binding protein YP_002415595.1 5189402 R 585056 CDS YP_002415596.1 218708077 7159437 5191280..5193217 1 NC_011751.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5193217 slt 7159437 slt Escherichia coli UMN026 lytic murein transglycosylase YP_002415596.1 5191280 D 585056 CDS YP_002415597.1 218708078 7157935 5193307..5193633 1 NC_011751.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5193633 trpR 7157935 trpR Escherichia coli UMN026 Trp operon repressor YP_002415597.1 5193307 D 585056 CDS YP_002415598.1 218708079 7158123 complement(5193627..5194151) 1 NC_011751.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 5194151 yjjX 7158123 yjjX Escherichia coli UMN026 NTPase YP_002415598.1 5193627 R 585056 CDS YP_002415599.1 218708080 7159445 5194194..5194841 1 NC_011751.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5194841 ytjC 7159445 ytjC Escherichia coli UMN026 phosphoglycerate mutase YP_002415599.1 5194194 D 585056 CDS YP_002415600.1 218708081 7159683 complement(5194838..5195707) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator; DNA-binding transcriptional activator 5195707 rob 7159683 rob Escherichia coli UMN026 DNA-binding transcriptional activator YP_002415600.1 5194838 R 585056 CDS YP_002415601.1 218708082 7157720 5195918..5196391 1 NC_011751.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900; hypothetical protein 5196391 creA 7157720 creA Escherichia coli UMN026 hypothetical protein YP_002415601.1 5195918 D 585056 CDS YP_002415602.1 218708083 7156010 5196404..5197093 1 NC_011751.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5197093 creB 7156010 creB Escherichia coli UMN026 DNA-binding response regulator CreB YP_002415602.1 5196404 D 585056 CDS YP_002415603.1 218708084 7156011 5197093..5198517 1 NC_011751.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5198517 creC 7156011 creC Escherichia coli UMN026 sensory histidine kinase CreC YP_002415603.1 5197093 D 585056 CDS YP_002415604.1 218708085 7156012 5198575..5199927 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88216172, 2835585, 2984198, 3531171; Product type m : membrane component; hypothetical protein 5199927 creD 7156012 creD Escherichia coli UMN026 hypothetical protein YP_002415604.1 5198575 D 585056 CDS YP_002415605.1 218708086 7156013 complement(5199987..5200703) 1 NC_011751.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator; two-component response regulator 5200703 arcA 7156013 arcA Escherichia coli UMN026 two-component response regulator YP_002415605.1 5199987 R 585056 CDS YP_002415606.1 218708087 7155766 5201339..5202025 1 NC_011751.1 member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 5202025 yjtD 7155766 yjtD Escherichia coli UMN026 putative RNA methyltransferase YP_002415606.1 5201339 D 585056 CDS